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Search of human proteins with 9257180
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|9257180 adducin 2 isoform c [Homo sapiens]
(420 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|9257180 adducin 2 isoform c [Homo sapiens] 820 0.0
gi|9257192 adducin 2 isoform a [Homo sapiens] 452 e-127
gi|89276790 adducin 2 isoform d [Homo sapiens] 445 e-125
gi|9257190 adducin 2 isoform e [Homo sapiens] 374 e-103
gi|89276787 adducin 2 isoform b [Homo sapiens] 374 e-103
gi|9951927 adducin 3 (gamma) isoform b [Homo sapiens] 222 4e-58
gi|62912453 adducin 3 (gamma) isoform b [Homo sapiens] 222 4e-58
gi|9943848 adducin 3 (gamma) isoform a [Homo sapiens] 222 4e-58
gi|29826325 adducin 1 (alpha) isoform d [Homo sapiens] 208 6e-54
gi|29826323 adducin 1 (alpha) isoform c [Homo sapiens] 208 6e-54
gi|29826321 adducin 1 (alpha) isoform b [Homo sapiens] 208 6e-54
gi|29826319 adducin 1 (alpha) isoform a [Homo sapiens] 208 6e-54
gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens] 62 1e-09
gi|5174573 myeloid/lymphoid or mixed-lineage leukemia trithorax ... 50 3e-06
gi|168229156 NFKB activating protein [Homo sapiens] 50 4e-06
gi|42518068 trans-golgi network protein 2 [Homo sapiens] 49 9e-06
gi|148596949 nucleolar and coiled-body phosphoprotein 1 [Homo sa... 48 1e-05
gi|117935038 cylicin, basic protein of sperm head cytoskeleton 1... 48 1e-05
gi|157738649 neurofilament, medium polypeptide 150kDa isoform 1 ... 47 2e-05
gi|157738641 neurofilament, medium polypeptide 150kDa isoform 2 ... 47 2e-05
gi|117414137 retinitis pigmentosa 1-like 1 [Homo sapiens] 47 2e-05
gi|118498359 ribosomal L1 domain containing 1 [Homo sapiens] 47 3e-05
gi|155030232 proline, glutamic acid and leucine rich protein 1 [... 47 4e-05
gi|157738619 smoothelin-like 1 [Homo sapiens] 45 9e-05
gi|7662238 apoptotic chromatin condensation inducer 1 [Homo sapi... 45 1e-04
gi|153945728 microtubule-associated protein 1B [Homo sapiens] 45 1e-04
gi|189181724 proteoglycan 4 isoform D [Homo sapiens] 45 2e-04
gi|189181722 proteoglycan 4 isoform C [Homo sapiens] 45 2e-04
gi|189181720 proteoglycan 4 isoform B [Homo sapiens] 45 2e-04
gi|67190163 proteoglycan 4 isoform A [Homo sapiens] 45 2e-04
>gi|9257180 adducin 2 isoform c [Homo sapiens]
Length = 420
Score = 820 bits (2117), Expect = 0.0
Identities = 420/420 (100%), Positives = 420/420 (100%)
Query: 1 MSEETVPEAASPPPPQGQPYFDRFSEDDPEYMRLRNRAADLRQDFNLMEQKKRVTMILQS 60
MSEETVPEAASPPPPQGQPYFDRFSEDDPEYMRLRNRAADLRQDFNLMEQKKRVTMILQS
Sbjct: 1 MSEETVPEAASPPPPQGQPYFDRFSEDDPEYMRLRNRAADLRQDFNLMEQKKRVTMILQS 60
Query: 61 PSFREELEGLIQEQMKKGNNSSNIWALRQIADFMASTSHAVFPTSSMNVSMMTPINDLHT 120
PSFREELEGLIQEQMKKGNNSSNIWALRQIADFMASTSHAVFPTSSMNVSMMTPINDLHT
Sbjct: 61 PSFREELEGLIQEQMKKGNNSSNIWALRQIADFMASTSHAVFPTSSMNVSMMTPINDLHT 120
Query: 121 ADSLNLAKGERLMRCKISSVYRLLDLYGWAQLSDTYVTLRVSKEQDHFLISPKGVSCSEV 180
ADSLNLAKGERLMRCKISSVYRLLDLYGWAQLSDTYVTLRVSKEQDHFLISPKGVSCSEV
Sbjct: 121 ADSLNLAKGERLMRCKISSVYRLLDLYGWAQLSDTYVTLRVSKEQDHFLISPKGVSCSEV 180
Query: 181 TASSLIKEVLEMRNKIREQNRQDVKSAGPQSQLLASVIAEKSRSPSTESQLMSKGDEDTK 240
TASSLIKEVLEMRNKIREQNRQDVKSAGPQSQLLASVIAEKSRSPSTESQLMSKGDEDTK
Sbjct: 181 TASSLIKEVLEMRNKIREQNRQDVKSAGPQSQLLASVIAEKSRSPSTESQLMSKGDEDTK 240
Query: 241 DDSEETVPNPFSQLTDQELEEYKKEVERKKLELDGEKETAPEEPGSPAKSAPASPVQSPA 300
DDSEETVPNPFSQLTDQELEEYKKEVERKKLELDGEKETAPEEPGSPAKSAPASPVQSPA
Sbjct: 241 DDSEETVPNPFSQLTDQELEEYKKEVERKKLELDGEKETAPEEPGSPAKSAPASPVQSPA 300
Query: 301 KEAETKSPLVSPSKSLEEGTKKTETSKAATTEPETTQPEGVVVNGREEEQTAEEILSKGL 360
KEAETKSPLVSPSKSLEEGTKKTETSKAATTEPETTQPEGVVVNGREEEQTAEEILSKGL
Sbjct: 301 KEAETKSPLVSPSKSLEEGTKKTETSKAATTEPETTQPEGVVVNGREEEQTAEEILSKGL 360
Query: 361 SQMTTSADTDVDTSKDKTESVTSGPMSPEGSPSKSPSKKKKKFRTPSFLKKSKKKEKVES 420
SQMTTSADTDVDTSKDKTESVTSGPMSPEGSPSKSPSKKKKKFRTPSFLKKSKKKEKVES
Sbjct: 361 SQMTTSADTDVDTSKDKTESVTSGPMSPEGSPSKSPSKKKKKFRTPSFLKKSKKKEKVES 420
>gi|9257192 adducin 2 isoform a [Homo sapiens]
Length = 726
Score = 452 bits (1162), Expect = e-127
Identities = 244/294 (82%), Positives = 252/294 (85%), Gaps = 22/294 (7%)
Query: 149 WAQLSDTYVTLRVSKEQDHFLISPKG----VSCSEVTASSL------------------I 186
W +TY+ + V+ E + SP+ + EV SS
Sbjct: 433 WLNTPNTYLRVNVADEVQRSMGSPRPKTTWMKADEVEKSSSGMPIRIENPNQFVPLYTDP 492
Query: 187 KEVLEMRNKIREQNRQDVKSAGPQSQLLASVIAEKSRSPSTESQLMSKGDEDTKDDSEET 246
+EVLEMRNKIREQNRQDVKSAGPQSQLLASVIAEKSRSPSTESQLMSKGDEDTKDDSEET
Sbjct: 493 QEVLEMRNKIREQNRQDVKSAGPQSQLLASVIAEKSRSPSTESQLMSKGDEDTKDDSEET 552
Query: 247 VPNPFSQLTDQELEEYKKEVERKKLELDGEKETAPEEPGSPAKSAPASPVQSPAKEAETK 306
VPNPFSQLTDQELEEYKKEVERKKLELDGEKETAPEEPGSPAKSAPASPVQSPAKEAETK
Sbjct: 553 VPNPFSQLTDQELEEYKKEVERKKLELDGEKETAPEEPGSPAKSAPASPVQSPAKEAETK 612
Query: 307 SPLVSPSKSLEEGTKKTETSKAATTEPETTQPEGVVVNGREEEQTAEEILSKGLSQMTTS 366
SPLVSPSKSLEEGTKKTETSKAATTEPETTQPEGVVVNGREEEQTAEEILSKGLSQMTTS
Sbjct: 613 SPLVSPSKSLEEGTKKTETSKAATTEPETTQPEGVVVNGREEEQTAEEILSKGLSQMTTS 672
Query: 367 ADTDVDTSKDKTESVTSGPMSPEGSPSKSPSKKKKKFRTPSFLKKSKKKEKVES 420
ADTDVDTSKDKTESVTSGPMSPEGSPSKSPSKKKKKFRTPSFLKKSKKKEKVES
Sbjct: 673 ADTDVDTSKDKTESVTSGPMSPEGSPSKSPSKKKKKFRTPSFLKKSKKKEKVES 726
Score = 374 bits (959), Expect = e-103
Identities = 187/187 (100%), Positives = 187/187 (100%)
Query: 1 MSEETVPEAASPPPPQGQPYFDRFSEDDPEYMRLRNRAADLRQDFNLMEQKKRVTMILQS 60
MSEETVPEAASPPPPQGQPYFDRFSEDDPEYMRLRNRAADLRQDFNLMEQKKRVTMILQS
Sbjct: 1 MSEETVPEAASPPPPQGQPYFDRFSEDDPEYMRLRNRAADLRQDFNLMEQKKRVTMILQS 60
Query: 61 PSFREELEGLIQEQMKKGNNSSNIWALRQIADFMASTSHAVFPTSSMNVSMMTPINDLHT 120
PSFREELEGLIQEQMKKGNNSSNIWALRQIADFMASTSHAVFPTSSMNVSMMTPINDLHT
Sbjct: 61 PSFREELEGLIQEQMKKGNNSSNIWALRQIADFMASTSHAVFPTSSMNVSMMTPINDLHT 120
Query: 121 ADSLNLAKGERLMRCKISSVYRLLDLYGWAQLSDTYVTLRVSKEQDHFLISPKGVSCSEV 180
ADSLNLAKGERLMRCKISSVYRLLDLYGWAQLSDTYVTLRVSKEQDHFLISPKGVSCSEV
Sbjct: 121 ADSLNLAKGERLMRCKISSVYRLLDLYGWAQLSDTYVTLRVSKEQDHFLISPKGVSCSEV 180
Query: 181 TASSLIK 187
TASSLIK
Sbjct: 181 TASSLIK 187
>gi|89276790 adducin 2 isoform d [Homo sapiens]
Length = 253
Score = 445 bits (1144), Expect = e-125
Identities = 229/237 (96%), Positives = 230/237 (97%), Gaps = 1/237 (0%)
Query: 1 MSEETVPEAASPPPPQGQPYFDRFSEDDPEYMRLRNRAADLRQDFNLMEQKKRVTMILQS 60
MSEETVPEAASPPPPQGQPYFDRFSEDDPEYMRLRNRAADLRQDFNLMEQKKRVTMILQS
Sbjct: 1 MSEETVPEAASPPPPQGQPYFDRFSEDDPEYMRLRNRAADLRQDFNLMEQKKRVTMILQS 60
Query: 61 PSFREELEGLIQEQMKKGNNSSNIWALRQIADFMASTSHAVFPTSSMNVSMMTPINDLHT 120
PSFREELEGLIQEQMKKGNNSSNIWALRQIADFMASTSHAVFPTSSMNVSMMTPINDLHT
Sbjct: 61 PSFREELEGLIQEQMKKGNNSSNIWALRQIADFMASTSHAVFPTSSMNVSMMTPINDLHT 120
Query: 121 ADSLNLAKGERLMRCKISSVYRLLDLYGWAQLSDTYVTLRVSKEQDHFLISPKGVSCSEV 180
ADSLNLAKGERLMRCKISSVYRLLDLYGWAQLSDTYVTLRVSKEQDHFLISPKGVSCSEV
Sbjct: 121 ADSLNLAKGERLMRCKISSVYRLLDLYGWAQLSDTYVTLRVSKEQDHFLISPKGVSCSEV 180
Query: 181 TASSLIKEVLEMRNKIREQNRQDVKSAGPQSQLLASVIAEKSRSPSTESQLMSKGDE 237
TASSLIKEVLEMRNKIREQNRQDVKSAGPQSQLLASVIAEKSRSP E +L G E
Sbjct: 181 TASSLIKEVLEMRNKIREQNRQDVKSAGPQSQLLASVIAEKSRSP-VEQRLPLTGGE 236
>gi|9257190 adducin 2 isoform e [Homo sapiens]
Length = 643
Score = 374 bits (959), Expect = e-103
Identities = 187/187 (100%), Positives = 187/187 (100%)
Query: 1 MSEETVPEAASPPPPQGQPYFDRFSEDDPEYMRLRNRAADLRQDFNLMEQKKRVTMILQS 60
MSEETVPEAASPPPPQGQPYFDRFSEDDPEYMRLRNRAADLRQDFNLMEQKKRVTMILQS
Sbjct: 1 MSEETVPEAASPPPPQGQPYFDRFSEDDPEYMRLRNRAADLRQDFNLMEQKKRVTMILQS 60
Query: 61 PSFREELEGLIQEQMKKGNNSSNIWALRQIADFMASTSHAVFPTSSMNVSMMTPINDLHT 120
PSFREELEGLIQEQMKKGNNSSNIWALRQIADFMASTSHAVFPTSSMNVSMMTPINDLHT
Sbjct: 61 PSFREELEGLIQEQMKKGNNSSNIWALRQIADFMASTSHAVFPTSSMNVSMMTPINDLHT 120
Query: 121 ADSLNLAKGERLMRCKISSVYRLLDLYGWAQLSDTYVTLRVSKEQDHFLISPKGVSCSEV 180
ADSLNLAKGERLMRCKISSVYRLLDLYGWAQLSDTYVTLRVSKEQDHFLISPKGVSCSEV
Sbjct: 121 ADSLNLAKGERLMRCKISSVYRLLDLYGWAQLSDTYVTLRVSKEQDHFLISPKGVSCSEV 180
Query: 181 TASSLIK 187
TASSLIK
Sbjct: 181 TASSLIK 187
Score = 175 bits (444), Expect = 6e-44
Identities = 105/161 (65%), Positives = 113/161 (70%), Gaps = 26/161 (16%)
Query: 149 WAQLSDTYVTLRVSKEQDHFLISPKG----VSCSEVTASSL------------------I 186
W +TY+ + V+ E + SP+ + EV SS
Sbjct: 433 WLNTPNTYLRVNVADEVQRSMGSPRPKTTWMKADEVEKSSSGMPIRIENPNQFVPLYTDP 492
Query: 187 KEVLEMRNKIREQNRQDVKSAGPQSQLLASVIAEKSRSPSTESQLMSKGDEDTKDDSEET 246
+EVLEMRNKIREQNRQDVKSAGPQSQLLASVIAEKSRSPSTESQLMSKGDEDTKDDSEET
Sbjct: 493 QEVLEMRNKIREQNRQDVKSAGPQSQLLASVIAEKSRSPSTESQLMSKGDEDTKDDSEET 552
Query: 247 VPNPFSQLTDQELEEYKKEVERKKLELDGEKETAPE-EPGS 286
VPNPFSQLTDQELEEYKKEVERKKLELD ET E EPGS
Sbjct: 553 VPNPFSQLTDQELEEYKKEVERKKLELD---ETGQEREPGS 590
>gi|89276787 adducin 2 isoform b [Homo sapiens]
Length = 559
Score = 374 bits (959), Expect = e-103
Identities = 187/187 (100%), Positives = 187/187 (100%)
Query: 1 MSEETVPEAASPPPPQGQPYFDRFSEDDPEYMRLRNRAADLRQDFNLMEQKKRVTMILQS 60
MSEETVPEAASPPPPQGQPYFDRFSEDDPEYMRLRNRAADLRQDFNLMEQKKRVTMILQS
Sbjct: 1 MSEETVPEAASPPPPQGQPYFDRFSEDDPEYMRLRNRAADLRQDFNLMEQKKRVTMILQS 60
Query: 61 PSFREELEGLIQEQMKKGNNSSNIWALRQIADFMASTSHAVFPTSSMNVSMMTPINDLHT 120
PSFREELEGLIQEQMKKGNNSSNIWALRQIADFMASTSHAVFPTSSMNVSMMTPINDLHT
Sbjct: 61 PSFREELEGLIQEQMKKGNNSSNIWALRQIADFMASTSHAVFPTSSMNVSMMTPINDLHT 120
Query: 121 ADSLNLAKGERLMRCKISSVYRLLDLYGWAQLSDTYVTLRVSKEQDHFLISPKGVSCSEV 180
ADSLNLAKGERLMRCKISSVYRLLDLYGWAQLSDTYVTLRVSKEQDHFLISPKGVSCSEV
Sbjct: 121 ADSLNLAKGERLMRCKISSVYRLLDLYGWAQLSDTYVTLRVSKEQDHFLISPKGVSCSEV 180
Query: 181 TASSLIK 187
TASSLIK
Sbjct: 181 TASSLIK 187
Score = 77.4 bits (189), Expect = 2e-14
Identities = 53/111 (47%), Positives = 62/111 (55%), Gaps = 23/111 (20%)
Query: 149 WAQLSDTYVTLRVSKEQDHFLISPKG----VSCSEVTASSL------------------I 186
W +TY+ + V+ E + SP+ + EV SS
Sbjct: 433 WLNTPNTYLRVNVADEVQRSMGSPRPKTTWMKADEVEKSSSGMPIRIENPNQFVPLYTDP 492
Query: 187 KEVLEMRNKIREQNRQDVKSAGPQSQLLASVIAEKSRSPSTESQLMSKGDE 237
+EVLEMRNKIREQNRQDVKSAGPQSQLLASVIAEKSRSP E +L G E
Sbjct: 493 QEVLEMRNKIREQNRQDVKSAGPQSQLLASVIAEKSRSP-VEQRLPLTGGE 542
>gi|9951927 adducin 3 (gamma) isoform b [Homo sapiens]
Length = 674
Score = 222 bits (566), Expect = 4e-58
Identities = 106/191 (55%), Positives = 148/191 (77%), Gaps = 4/191 (2%)
Query: 1 MSEETVPEAASPPPPQGQP----YFDRFSEDDPEYMRLRNRAADLRQDFNLMEQKKRVTM 56
MS + + PPP P YFDR +E+DPEY+R RN + DLRQDFN+MEQ+KRVT
Sbjct: 1 MSSDASQGVITTPPPPSMPHKERYFDRINENDPEYIRERNMSPDLRQDFNMMEQRKRVTQ 60
Query: 57 ILQSPSFREELEGLIQEQMKKGNNSSNIWALRQIADFMASTSHAVFPTSSMNVSMMTPIN 116
ILQSP+FRE+LE LIQEQMKKG+N + + AL+QIAD++ + S + F + +++ M+TPIN
Sbjct: 61 ILQSPAFREDLECLIQEQMKKGHNPTGLLALQQIADYIMANSFSGFSSPPLSLGMVTPIN 120
Query: 117 DLHTADSLNLAKGERLMRCKISSVYRLLDLYGWAQLSDTYVTLRVSKEQDHFLISPKGVS 176
DL AD+ + KGE+L RCK++S+YRL+DL+GWA L++TY+++R+SKEQDH +I P+G+S
Sbjct: 121 DLPGADTSSYVKGEKLTRCKLASLYRLVDLFGWAHLANTYISVRISKEQDHIIIIPRGLS 180
Query: 177 CSEVTASSLIK 187
SE TAS+L+K
Sbjct: 181 FSEATASNLVK 191
Score = 129 bits (325), Expect = 4e-30
Identities = 108/294 (36%), Positives = 137/294 (46%), Gaps = 80/294 (27%)
Query: 149 WAQLSDTYVTLRVSKEQDHFLISP-------KGVSCSEVTASSLIK-------------- 187
W +TY+ + V +E + SP K S+V+ + IK
Sbjct: 439 WLNSPNTYMKVNVPEESRNGETSPRTKITWMKAEDSSKVSGGTPIKIEDPNQFVPLNTNP 498
Query: 188 -EVLEMRNKIREQNRQDVKSAGPQSQLLASVIAEKSRSPSTESQLMSKGDEDTKDDSEET 246
EVLE RNKIREQNR D+K+AGPQSQLLA ++ +K PST M D+ D
Sbjct: 499 NEVLEKRNKIREQNRYDLKTAGPQSQLLAGIVVDK--PPST----MQFEDD---DHGPPA 549
Query: 247 VPNPFSQLTDQELEEYKKEVERKKLELDGEKETAPEEPGSPAKSAPASPVQSPAKEAETK 306
PNPFS LT+ ELEEYK+ +ERK+ L+ E S ++ P K
Sbjct: 550 PPNPFSHLTEGELEEYKRTIERKQQGLEENHELF---------SKSFISMEVPVMVVNGK 600
Query: 307 SPLVSPSKSLEEGTKKTETSKAATTEPETTQPEGVVVNGREEEQTAEEILSKGLSQMTTS 366
+ L + + TS T E + EI K
Sbjct: 601 DDMHDVEDELAKRVSRLSTS---------TTIENI------------EITIK-------- 631
Query: 367 ADTDVDTSKDKTESVTSGPMSPEGSPSKSPSKKKKKFRTPSFLKKSKKKEKVES 420
S +K E V +SPEGSPSKSPSKKKKKFRTPSFLKK+KKKEKVE+
Sbjct: 632 -------SPEKIEEV----LSPEGSPSKSPSKKKKKFRTPSFLKKNKKKEKVEA 674
>gi|62912453 adducin 3 (gamma) isoform b [Homo sapiens]
Length = 674
Score = 222 bits (566), Expect = 4e-58
Identities = 106/191 (55%), Positives = 148/191 (77%), Gaps = 4/191 (2%)
Query: 1 MSEETVPEAASPPPPQGQP----YFDRFSEDDPEYMRLRNRAADLRQDFNLMEQKKRVTM 56
MS + + PPP P YFDR +E+DPEY+R RN + DLRQDFN+MEQ+KRVT
Sbjct: 1 MSSDASQGVITTPPPPSMPHKERYFDRINENDPEYIRERNMSPDLRQDFNMMEQRKRVTQ 60
Query: 57 ILQSPSFREELEGLIQEQMKKGNNSSNIWALRQIADFMASTSHAVFPTSSMNVSMMTPIN 116
ILQSP+FRE+LE LIQEQMKKG+N + + AL+QIAD++ + S + F + +++ M+TPIN
Sbjct: 61 ILQSPAFREDLECLIQEQMKKGHNPTGLLALQQIADYIMANSFSGFSSPPLSLGMVTPIN 120
Query: 117 DLHTADSLNLAKGERLMRCKISSVYRLLDLYGWAQLSDTYVTLRVSKEQDHFLISPKGVS 176
DL AD+ + KGE+L RCK++S+YRL+DL+GWA L++TY+++R+SKEQDH +I P+G+S
Sbjct: 121 DLPGADTSSYVKGEKLTRCKLASLYRLVDLFGWAHLANTYISVRISKEQDHIIIIPRGLS 180
Query: 177 CSEVTASSLIK 187
SE TAS+L+K
Sbjct: 181 FSEATASNLVK 191
Score = 129 bits (325), Expect = 4e-30
Identities = 108/294 (36%), Positives = 137/294 (46%), Gaps = 80/294 (27%)
Query: 149 WAQLSDTYVTLRVSKEQDHFLISP-------KGVSCSEVTASSLIK-------------- 187
W +TY+ + V +E + SP K S+V+ + IK
Sbjct: 439 WLNSPNTYMKVNVPEESRNGETSPRTKITWMKAEDSSKVSGGTPIKIEDPNQFVPLNTNP 498
Query: 188 -EVLEMRNKIREQNRQDVKSAGPQSQLLASVIAEKSRSPSTESQLMSKGDEDTKDDSEET 246
EVLE RNKIREQNR D+K+AGPQSQLLA ++ +K PST M D+ D
Sbjct: 499 NEVLEKRNKIREQNRYDLKTAGPQSQLLAGIVVDK--PPST----MQFEDD---DHGPPA 549
Query: 247 VPNPFSQLTDQELEEYKKEVERKKLELDGEKETAPEEPGSPAKSAPASPVQSPAKEAETK 306
PNPFS LT+ ELEEYK+ +ERK+ L+ E S ++ P K
Sbjct: 550 PPNPFSHLTEGELEEYKRTIERKQQGLEENHELF---------SKSFISMEVPVMVVNGK 600
Query: 307 SPLVSPSKSLEEGTKKTETSKAATTEPETTQPEGVVVNGREEEQTAEEILSKGLSQMTTS 366
+ L + + TS T E + EI K
Sbjct: 601 DDMHDVEDELAKRVSRLSTS---------TTIENI------------EITIK-------- 631
Query: 367 ADTDVDTSKDKTESVTSGPMSPEGSPSKSPSKKKKKFRTPSFLKKSKKKEKVES 420
S +K E V +SPEGSPSKSPSKKKKKFRTPSFLKK+KKKEKVE+
Sbjct: 632 -------SPEKIEEV----LSPEGSPSKSPSKKKKKFRTPSFLKKNKKKEKVEA 674
>gi|9943848 adducin 3 (gamma) isoform a [Homo sapiens]
Length = 706
Score = 222 bits (566), Expect = 4e-58
Identities = 106/191 (55%), Positives = 148/191 (77%), Gaps = 4/191 (2%)
Query: 1 MSEETVPEAASPPPPQGQP----YFDRFSEDDPEYMRLRNRAADLRQDFNLMEQKKRVTM 56
MS + + PPP P YFDR +E+DPEY+R RN + DLRQDFN+MEQ+KRVT
Sbjct: 1 MSSDASQGVITTPPPPSMPHKERYFDRINENDPEYIRERNMSPDLRQDFNMMEQRKRVTQ 60
Query: 57 ILQSPSFREELEGLIQEQMKKGNNSSNIWALRQIADFMASTSHAVFPTSSMNVSMMTPIN 116
ILQSP+FRE+LE LIQEQMKKG+N + + AL+QIAD++ + S + F + +++ M+TPIN
Sbjct: 61 ILQSPAFREDLECLIQEQMKKGHNPTGLLALQQIADYIMANSFSGFSSPPLSLGMVTPIN 120
Query: 117 DLHTADSLNLAKGERLMRCKISSVYRLLDLYGWAQLSDTYVTLRVSKEQDHFLISPKGVS 176
DL AD+ + KGE+L RCK++S+YRL+DL+GWA L++TY+++R+SKEQDH +I P+G+S
Sbjct: 121 DLPGADTSSYVKGEKLTRCKLASLYRLVDLFGWAHLANTYISVRISKEQDHIIIIPRGLS 180
Query: 177 CSEVTASSLIK 187
SE TAS+L+K
Sbjct: 181 FSEATASNLVK 191
Score = 163 bits (413), Expect = 2e-40
Identities = 120/295 (40%), Positives = 161/295 (54%), Gaps = 50/295 (16%)
Query: 149 WAQLSDTYVTLRVSKEQDHFLISP-------KGVSCSEVTASSLIK-------------- 187
W +TY+ + V +E + SP K S+V+ + IK
Sbjct: 439 WLNSPNTYMKVNVPEESRNGETSPRTKITWMKAEDSSKVSGGTPIKIEDPNQFVPLNTNP 498
Query: 188 -EVLEMRNKIREQNRQDVKSAGPQSQLLASVIAEKSRSPSTESQLMSKGDEDTKDDSEET 246
EVLE RNKIREQNR D+K+AGPQSQLLA ++ +K PST M D+D
Sbjct: 499 NEVLEKRNKIREQNRYDLKTAGPQSQLLAGIVVDKP--PST----MQFEDDD---HGPPA 549
Query: 247 VPNPFSQLTDQELEEYKKEVERKKLEL-DGEKETAPEEPGSPAKSAPASPVQSPAKEAET 305
PNPFS LT+ ELEEYK+ +ERK+ L D E+E ++ S S +QS +T
Sbjct: 550 PPNPFSHLTEGELEEYKRTIERKQQGLEDAEQELLSDDASS------VSQIQS-----QT 598
Query: 306 KSPLVSPSKSLEEGTKKTETSKAATTEPETTQPEGVVVNGREEEQTAEEILSKGLSQMTT 365
+SP P K LEE + S + P +VVNG+++ E+ L+K +S+++T
Sbjct: 599 QSPQNVPEK-LEENHELFSKSFISMEVPV------MVVNGKDDMHDVEDELAKRVSRLST 651
Query: 366 SADTDVDTSKDKTESVTSGPMSPEGSPSKSPSKKKKKFRTPSFLKKSKKKEKVES 420
S + K+ +SPEGSPSKSPSKKKKKFRTPSFLKK+KKKEKVE+
Sbjct: 652 STTIENIEITIKSPEKIEEVLSPEGSPSKSPSKKKKKFRTPSFLKKNKKKEKVEA 706
>gi|29826325 adducin 1 (alpha) isoform d [Homo sapiens]
Length = 662
Score = 208 bits (530), Expect = 6e-54
Identities = 110/209 (52%), Positives = 145/209 (69%), Gaps = 11/209 (5%)
Query: 11 SPPP---PQGQPYFDRFSEDDPEYMRLRNRAADLRQDFNLMEQKKRVTMILQSPSFREEL 67
SPPP P + YFDR E++PEY+R RN A DLRQDFN+MEQKKRV+MILQSP+F EEL
Sbjct: 12 SPPPTTAPHKERYFDRVDENNPEYLRERNMAPDLRQDFNMMEQKKRVSMILQSPAFCEEL 71
Query: 68 EGLIQEQMKKGNNSSNIWALRQIADFMASTSHAVFPTS--------SMNVSMMTPINDLH 119
E +IQEQ KKG N + + AL+QIADFM + V+P + +M++ M+TP+NDL
Sbjct: 72 ESMIQEQFKKGKNPTGLLALQQIADFMTTNVPNVYPAAPQGGMAALNMSLGMVTPVNDLR 131
Query: 120 TADSLNLAKGERLMRCKISSVYRLLDLYGWAQLSDTYVTLRVSKEQDHFLISPKGVSCSE 179
+DS+ KGE+L+RCK+++ YRL DL+GW+QL ++T RV+ EQ+HFLI P G+ SE
Sbjct: 132 GSDSIAYDKGEKLLRCKLAAFYRLADLFGWSQLIYNHITTRVNSEQEHFLIVPFGLLYSE 191
Query: 180 VTASSLIKEVLEMRNKIREQNRQDVKSAG 208
VTASSL+K L+ R V AG
Sbjct: 192 VTASSLVKINLQGDIVDRGSTNLGVNQAG 220
Score = 89.7 bits (221), Expect = 4e-18
Identities = 60/136 (44%), Positives = 77/136 (56%), Gaps = 14/136 (10%)
Query: 187 KEVLEMRNKIREQNRQDVKSAGPQSQLLASVIAEKSRSPS---TESQLMSKGDEDTKDDS 243
KEV EMRNKIREQN QD+K+AGPQSQ+L V+ ++S T S+ + + +
Sbjct: 528 KEVQEMRNKIREQNLQDIKTAGPQSQVLCGVVMDRSLVQGELVTASKAIIEKEYQPHVIV 587
Query: 244 EETVPNPFSQLTDQELEEYKKEVERKKLELDGEKETAPEEPGSPAKSAPASPVQSPAKEA 303
T PNPF+ LTD+ELEEY++EVERK+ G +E E KS P P A
Sbjct: 588 STTGPNPFTTLTDRELEEYRREVERKQ---KGSEENLDEAREQKEKSPPDQP-------A 637
Query: 304 ETKSPLVSPSKSLEEG 319
P +P K LEEG
Sbjct: 638 VPHPPPSTPIK-LEEG 652
>gi|29826323 adducin 1 (alpha) isoform c [Homo sapiens]
Length = 631
Score = 208 bits (530), Expect = 6e-54
Identities = 110/209 (52%), Positives = 145/209 (69%), Gaps = 11/209 (5%)
Query: 11 SPPP---PQGQPYFDRFSEDDPEYMRLRNRAADLRQDFNLMEQKKRVTMILQSPSFREEL 67
SPPP P + YFDR E++PEY+R RN A DLRQDFN+MEQKKRV+MILQSP+F EEL
Sbjct: 12 SPPPTTAPHKERYFDRVDENNPEYLRERNMAPDLRQDFNMMEQKKRVSMILQSPAFCEEL 71
Query: 68 EGLIQEQMKKGNNSSNIWALRQIADFMASTSHAVFPTS--------SMNVSMMTPINDLH 119
E +IQEQ KKG N + + AL+QIADFM + V+P + +M++ M+TP+NDL
Sbjct: 72 ESMIQEQFKKGKNPTGLLALQQIADFMTTNVPNVYPAAPQGGMAALNMSLGMVTPVNDLR 131
Query: 120 TADSLNLAKGERLMRCKISSVYRLLDLYGWAQLSDTYVTLRVSKEQDHFLISPKGVSCSE 179
+DS+ KGE+L+RCK+++ YRL DL+GW+QL ++T RV+ EQ+HFLI P G+ SE
Sbjct: 132 GSDSIAYDKGEKLLRCKLAAFYRLADLFGWSQLIYNHITTRVNSEQEHFLIVPFGLLYSE 191
Query: 180 VTASSLIKEVLEMRNKIREQNRQDVKSAG 208
VTASSL+K L+ R V AG
Sbjct: 192 VTASSLVKINLQGDIVDRGSTNLGVNQAG 220
Score = 89.7 bits (221), Expect = 4e-18
Identities = 60/136 (44%), Positives = 77/136 (56%), Gaps = 14/136 (10%)
Query: 187 KEVLEMRNKIREQNRQDVKSAGPQSQLLASVIAEKSRSPS---TESQLMSKGDEDTKDDS 243
KEV EMRNKIREQN QD+K+AGPQSQ+L V+ ++S T S+ + + +
Sbjct: 497 KEVQEMRNKIREQNLQDIKTAGPQSQVLCGVVMDRSLVQGELVTASKAIIEKEYQPHVIV 556
Query: 244 EETVPNPFSQLTDQELEEYKKEVERKKLELDGEKETAPEEPGSPAKSAPASPVQSPAKEA 303
T PNPF+ LTD+ELEEY++EVERK+ G +E E KS P P A
Sbjct: 557 STTGPNPFTTLTDRELEEYRREVERKQ---KGSEENLDEAREQKEKSPPDQP-------A 606
Query: 304 ETKSPLVSPSKSLEEG 319
P +P K LEEG
Sbjct: 607 VPHPPPSTPIK-LEEG 621
>gi|29826321 adducin 1 (alpha) isoform b [Homo sapiens]
Length = 768
Score = 208 bits (530), Expect = 6e-54
Identities = 110/209 (52%), Positives = 145/209 (69%), Gaps = 11/209 (5%)
Query: 11 SPPP---PQGQPYFDRFSEDDPEYMRLRNRAADLRQDFNLMEQKKRVTMILQSPSFREEL 67
SPPP P + YFDR E++PEY+R RN A DLRQDFN+MEQKKRV+MILQSP+F EEL
Sbjct: 12 SPPPTTAPHKERYFDRVDENNPEYLRERNMAPDLRQDFNMMEQKKRVSMILQSPAFCEEL 71
Query: 68 EGLIQEQMKKGNNSSNIWALRQIADFMASTSHAVFPTS--------SMNVSMMTPINDLH 119
E +IQEQ KKG N + + AL+QIADFM + V+P + +M++ M+TP+NDL
Sbjct: 72 ESMIQEQFKKGKNPTGLLALQQIADFMTTNVPNVYPAAPQGGMAALNMSLGMVTPVNDLR 131
Query: 120 TADSLNLAKGERLMRCKISSVYRLLDLYGWAQLSDTYVTLRVSKEQDHFLISPKGVSCSE 179
+DS+ KGE+L+RCK+++ YRL DL+GW+QL ++T RV+ EQ+HFLI P G+ SE
Sbjct: 132 GSDSIAYDKGEKLLRCKLAAFYRLADLFGWSQLIYNHITTRVNSEQEHFLIVPFGLLYSE 191
Query: 180 VTASSLIKEVLEMRNKIREQNRQDVKSAG 208
VTASSL+K L+ R V AG
Sbjct: 192 VTASSLVKINLQGDIVDRGSTNLGVNQAG 220
Score = 132 bits (332), Expect = 6e-31
Identities = 87/238 (36%), Positives = 124/238 (52%), Gaps = 9/238 (3%)
Query: 187 KEVLEMRNKIREQNRQDVKSAGPQSQLLASVIAEKSRSPS---TESQLMSKGDEDTKDDS 243
KEV EMRNKIREQN QD+K+AGPQSQ+L V+ ++S T S+ + + +
Sbjct: 528 KEVQEMRNKIREQNLQDIKTAGPQSQVLCGVVMDRSLVQGELVTASKAIIEKEYQPHVIV 587
Query: 244 EETVPNPFSQLTDQELEEYKKEVERKKLELDGEKETAPEEPGSPAKSAPASPVQSPAKEA 303
T PNPF+ LTD+ELEEY++EVERK+ + + A E+ PA P P+
Sbjct: 588 STTGPNPFTTLTDRELEEYRREVERKQKGSEENLDEAREQKEKSPPDQPAVPHPPPSTPI 647
Query: 304 ETKSPLVSPSKSLEEGTKKTETSKAATTEP-ETTQPEGVVVNGREEEQTAEEILSKGLSQ 362
+ + LV + ++ T P E ++ G + +EEE ++ ++
Sbjct: 648 KLEEDLVPEPTTGDDSDAATFKPTLPDLSPDEPSEALGFPMLEKEEEAHRPPSPTEAPTE 707
Query: 363 MTTSADTD-----VDTSKDKTESVTSGPMSPEGSPSKSPSKKKKKFRTPSFLKKSKKK 415
+ D + + E + +GSP KSPSKKKKKFRTPSFLKKSKKK
Sbjct: 708 ASPEPAPDPAPVAEEAAPSAVEEGAAADPGSDGSPGKSPSKKKKKFRTPSFLKKSKKK 765
>gi|29826319 adducin 1 (alpha) isoform a [Homo sapiens]
Length = 737
Score = 208 bits (530), Expect = 6e-54
Identities = 110/209 (52%), Positives = 145/209 (69%), Gaps = 11/209 (5%)
Query: 11 SPPP---PQGQPYFDRFSEDDPEYMRLRNRAADLRQDFNLMEQKKRVTMILQSPSFREEL 67
SPPP P + YFDR E++PEY+R RN A DLRQDFN+MEQKKRV+MILQSP+F EEL
Sbjct: 12 SPPPTTAPHKERYFDRVDENNPEYLRERNMAPDLRQDFNMMEQKKRVSMILQSPAFCEEL 71
Query: 68 EGLIQEQMKKGNNSSNIWALRQIADFMASTSHAVFPTS--------SMNVSMMTPINDLH 119
E +IQEQ KKG N + + AL+QIADFM + V+P + +M++ M+TP+NDL
Sbjct: 72 ESMIQEQFKKGKNPTGLLALQQIADFMTTNVPNVYPAAPQGGMAALNMSLGMVTPVNDLR 131
Query: 120 TADSLNLAKGERLMRCKISSVYRLLDLYGWAQLSDTYVTLRVSKEQDHFLISPKGVSCSE 179
+DS+ KGE+L+RCK+++ YRL DL+GW+QL ++T RV+ EQ+HFLI P G+ SE
Sbjct: 132 GSDSIAYDKGEKLLRCKLAAFYRLADLFGWSQLIYNHITTRVNSEQEHFLIVPFGLLYSE 191
Query: 180 VTASSLIKEVLEMRNKIREQNRQDVKSAG 208
VTASSL+K L+ R V AG
Sbjct: 192 VTASSLVKINLQGDIVDRGSTNLGVNQAG 220
Score = 132 bits (332), Expect = 6e-31
Identities = 87/238 (36%), Positives = 124/238 (52%), Gaps = 9/238 (3%)
Query: 187 KEVLEMRNKIREQNRQDVKSAGPQSQLLASVIAEKSRSPS---TESQLMSKGDEDTKDDS 243
KEV EMRNKIREQN QD+K+AGPQSQ+L V+ ++S T S+ + + +
Sbjct: 497 KEVQEMRNKIREQNLQDIKTAGPQSQVLCGVVMDRSLVQGELVTASKAIIEKEYQPHVIV 556
Query: 244 EETVPNPFSQLTDQELEEYKKEVERKKLELDGEKETAPEEPGSPAKSAPASPVQSPAKEA 303
T PNPF+ LTD+ELEEY++EVERK+ + + A E+ PA P P+
Sbjct: 557 STTGPNPFTTLTDRELEEYRREVERKQKGSEENLDEAREQKEKSPPDQPAVPHPPPSTPI 616
Query: 304 ETKSPLVSPSKSLEEGTKKTETSKAATTEP-ETTQPEGVVVNGREEEQTAEEILSKGLSQ 362
+ + LV + ++ T P E ++ G + +EEE ++ ++
Sbjct: 617 KLEEDLVPEPTTGDDSDAATFKPTLPDLSPDEPSEALGFPMLEKEEEAHRPPSPTEAPTE 676
Query: 363 MTTSADTD-----VDTSKDKTESVTSGPMSPEGSPSKSPSKKKKKFRTPSFLKKSKKK 415
+ D + + E + +GSP KSPSKKKKKFRTPSFLKKSKKK
Sbjct: 677 ASPEPAPDPAPVAEEAAPSAVEEGAAADPGSDGSPGKSPSKKKKKFRTPSFLKKSKKK 734
>gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens]
Length = 1020
Score = 61.6 bits (148), Expect = 1e-09
Identities = 64/228 (28%), Positives = 98/228 (42%), Gaps = 22/228 (9%)
Query: 205 KSAGPQSQLLASVIAEKSRSPS---------TESQLMSKGDEDTKDDSEETVPNPFSQLT 255
++A P+ + S + E+++SP+ +S K E K ++E +P +
Sbjct: 508 EAASPEKE-AKSPVKEEAKSPAEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSP-PEAK 565
Query: 256 DQELEEYKKEVERKKLELDGEKETAPEEPGSPAKSAPASPVQSPAKE-----AETKSPLV 310
E EE K E K E K A EE SPA++ +SP KE AE KSP+
Sbjct: 566 SPEKEEAKSPAEVKSPE--KAKSPAKEEAKSPAEAKSPEKAKSPVKEEAKSPAEAKSPVK 623
Query: 311 SPSKSLEEGTKKTETSKAATTEPETTQPEGVVVNGREEEQTAEEILS--KGLSQMTTSAD 368
+KS E K E +K+ T E E PE +EE ++ E+ S K ++ A
Sbjct: 624 EEAKSPAE-VKSPEKAKSPTKE-EAKSPEKAKSPEKEEAKSPEKAKSPVKAEAKSPEKAK 681
Query: 369 TDVDTSKDKTESVTSGPMSPEGSPSKSPSKKKKKFRTPSFLKKSKKKE 416
+ V E S SP K+ S K++ ++P K K+E
Sbjct: 682 SPVKAEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKSPEKAKSPVKEE 729
Score = 58.2 bits (139), Expect = 1e-08
Identities = 62/236 (26%), Positives = 104/236 (44%), Gaps = 17/236 (7%)
Query: 191 EMRNKIREQNRQDVKSAGPQSQLLASVIA----EKSRSPSTESQLMSKGDEDTKDDSEET 246
E ++ ++E+ + ++ P+ + S EK++SP+ E +K + K +E
Sbjct: 515 EAKSPVKEEAKSPAEAKSPEKEEAKSPAEVKSPEKAKSPAKEE---AKSPPEAKSPEKEE 571
Query: 247 VPNPFSQLTDQELEEYKKEVERKKLELDG-EKETAP--EEPGSPAKSAPASPVQSPAKE- 302
+P + ++ + KE + E EK +P EE SPA++ SPV+ AK
Sbjct: 572 AKSPAEVKSPEKAKSPAKEEAKSPAEAKSPEKAKSPVKEEAKSPAEAK--SPVKEEAKSP 629
Query: 303 AETKSPLVSPSKSLEEGTKKTETSKAATTEPETTQPEGVVVNGREEEQTAEEILS--KGL 360
AE KSP + S + EE K E +K+ E E PE + E ++ E+ S K
Sbjct: 630 AEVKSPEKAKSPTKEE-AKSPEKAKSPEKE-EAKSPEKAKSPVKAEAKSPEKAKSPVKAE 687
Query: 361 SQMTTSADTDVDTSKDKTESVTSGPMSPEGSPSKSPSKKKKKFRTPSFLKKSKKKE 416
++ A + V E S SP K+ S K++ +TP K K+E
Sbjct: 688 AKSPEKAKSPVKEEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKTPEKAKSPVKEE 743
Score = 56.2 bits (134), Expect = 5e-08
Identities = 66/259 (25%), Positives = 108/259 (41%), Gaps = 26/259 (10%)
Query: 181 TASSLIKEVLEMRNKIREQNRQD---VKSAGPQSQLLASVIAEKSRSPSTESQLMSKG-- 235
+ S+ IK E + K+ E++ ++ V+ ++Q+ V E+ + E +G
Sbjct: 431 SVSTHIKVKSEEKIKVVEKSEKETVIVEEQTEETQVTEEVTEEEEKEAKEEEGKEEEGGE 490
Query: 236 DEDTKDDSEETVPNPFSQLTDQELEEYKKEVERKKLELDGEKETAPEEPGSPAKSAPASP 295
+E+ + EET P + E +E K V+ + K EE SPA+
Sbjct: 491 EEEAEGGEEETKSPPAEEAASPE-KEAKSPVKEEAKSPAEAKSPEKEEAKSPAEVKSPEK 549
Query: 296 VQSPAKEA-----ETKSPLVSPSKSLEEGTKKTETSKA-----ATTEPETTQPEGVVVNG 345
+SPAKE E KSP +KS E K E +K+ A + E PE
Sbjct: 550 AKSPAKEEAKSPPEAKSPEKEEAKSPAE-VKSPEKAKSPAKEEAKSPAEAKSPEKAKSPV 608
Query: 346 REEEQTAEEILSKGLSQMTTSADT-DVDTSKDKTESVTSGP---MSPEGSPSKSPSKKKK 401
+EE ++ E S + + A+ + +K T+ P SPE +KSP K K
Sbjct: 609 KEEAKSPAEAKSPVKEEAKSPAEVKSPEKAKSPTKEEAKSPEKAKSPEKEEAKSPEKAKS 668
Query: 402 KFRTPSFLKKSKKKEKVES 420
+ ++K EK +S
Sbjct: 669 PVKA-----EAKSPEKAKS 682
Score = 52.0 bits (123), Expect = 1e-06
Identities = 51/229 (22%), Positives = 93/229 (40%), Gaps = 23/229 (10%)
Query: 182 ASSLIKEVLEMRNK----IREQNRQDVKSAGPQSQLLASVIAEKSRSPSTESQLMSKGDE 237
A S +KE + K ++E+ + K+ P + S EK++SP L K E
Sbjct: 708 AKSPVKEEAKSPEKAKSPVKEEAKTPEKAKSPVKEEAKS--PEKAKSPEKAKTLDVKSPE 765
Query: 238 DTKDDSEETVPNPFSQLTDQELEEYKKEVERKKLELDGEKETAPEEPGSPAKSAPASPVQ 297
K ++E +P + ++ K+EV+ +PE+ SP K +P +
Sbjct: 766 -AKTPAKEEARSPADKFPEKAKSPVKEEVK------------SPEKAKSPLKEDAKAPEK 812
Query: 298 SPAKEAETKSPLVSPSK----SLEEGTKKTETSKAATTEPETTQPEGVVVNGREEEQTAE 353
K+ E KSP+ K ++E KK E KA T + + ++E
Sbjct: 813 EIPKKEEVKSPVKEEEKPQEVKVKEPPKKAEEEKAPATPKTEEKKDSKKEEAPKKEAPKP 872
Query: 354 EILSKGLSQMTTSADTDVDTSKDKTESVTSGPMSPEGSPSKSPSKKKKK 402
++ K + ++ V+ K++ E P + +P+K K+ K
Sbjct: 873 KVEEKKEPAVEKPKESKVEAKKEEAEDKKKVPTPEKEAPAKVEVKEDAK 921
Score = 48.1 bits (113), Expect = 1e-05
Identities = 52/259 (20%), Positives = 94/259 (36%), Gaps = 42/259 (16%)
Query: 187 KEVLEMRNKIREQNRQDVKSAGPQSQLLASVIAEKSRSPSTESQLMSKGDEDTKDDSEET 246
K E ++ ++E+ + + P EK++SP+ E +K E K +E
Sbjct: 613 KSPAEAKSPVKEEAKSPAEVKSP----------EKAKSPTKEE---AKSPEKAKSPEKEE 659
Query: 247 VPNPFSQLTDQELEEYKKEVERKKLELDG-----------EKETAPEEPGSPAKSAPASP 295
+P + + E E + ++ + E+ +PE+ SP K SP
Sbjct: 660 AKSPEKAKSPVKAEAKSPEKAKSPVKAEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKSP 719
Query: 296 --VQSPAKE-----AETKSPLVSPSKSLEEGTKKTETSKAATTEPETTQPEGVVVNG--- 345
+SP KE + KSP+ +KS E+ + PE P
Sbjct: 720 EKAKSPVKEEAKTPEKAKSPVKEEAKSPEKAKSPEKAKTLDVKSPEAKTPAKEEARSPAD 779
Query: 346 ----REEEQTAEEILSKGLSQMTTSADTDVDTSKDKTESVTSGPMSPEGSPS----KSPS 397
+ + EE+ S ++ D + + P+ E P K P
Sbjct: 780 KFPEKAKSPVKEEVKSPEKAKSPLKEDAKAPEKEIPKKEEVKSPVKEEEKPQEVKVKEPP 839
Query: 398 KKKKKFRTPSFLKKSKKKE 416
KK ++ + P+ K +KK+
Sbjct: 840 KKAEEEKAPATPKTEEKKD 858
Score = 47.0 bits (110), Expect = 3e-05
Identities = 59/226 (26%), Positives = 95/226 (42%), Gaps = 52/226 (23%)
Query: 191 EMRNKIREQNR-QDVKSAGPQSQLLASVIAEKSRSPSTESQLMSKGDEDTKDDSEETVPN 249
E+++ ++E+ + Q+VK P + AE+ ++P+T E+ KD +E P
Sbjct: 819 EVKSPVKEEEKPQEVKVKEPPKK------AEEEKAPATPKT------EEKKDSKKEEAP- 865
Query: 250 PFSQLTDQELEEYKKEVERKKLELDGEKETAPEEPGSPAKSAPASPVQSPAKEAETKSPL 309
KKE + K+E +KE A E+P S V++ +EAE K +
Sbjct: 866 -------------KKEAPKPKVE--EKKEPAVEKP-------KESKVEAKKEEAEDKKKV 903
Query: 310 VSPSK------SLEEGTKKTETSKAATTEP------ETTQPEGVVVNGREEEQTAEEILS 357
+P K ++E K E ++ A EP E ++P E++ T EE
Sbjct: 904 PTPEKEAPAKVEVKEDAKPKEKTEVAKKEPDDAKAKEPSKPAEKKEAAPEKKDTKEEKAK 963
Query: 358 KGLSQMTTSADTDVDTSKDKTES-VTSGPMSPEGSPSKSPSKKKKK 402
K + T A D DKT S S P + + S S +K K
Sbjct: 964 KPEEKPKTEAKAKED---DKTLSKEPSKPKAEKAEKSSSTDQKDSK 1006
>gi|5174573 myeloid/lymphoid or mixed-lineage leukemia trithorax
homolog 2 [Homo sapiens]
Length = 1210
Score = 50.4 bits (119), Expect = 3e-06
Identities = 70/279 (25%), Positives = 119/279 (42%), Gaps = 36/279 (12%)
Query: 161 VSKEQDHFLISPKGVSCSEVTASSLIKEVLEMRNKIREQNRQDVK----SAGPQS--QLL 214
V++ Q + S K S S+ SS++++ L++ + + Q + S+ P S Q L
Sbjct: 398 VTQNQKQYDTSSKTHSNSQQGTSSMLEDDLQLSDSEDSDSEQTPEKPPSSSAPPSAPQSL 457
Query: 215 ASVIAEKSRSPSTESQLMSKGD-------EDTKDDSEET------VPNPFSQLTDQ-ELE 260
+A + S S ES+ S D E + DSEE P P T++ +L+
Sbjct: 458 PEPVAS-AHSSSAESESTSDSDSSSDSESESSSSDSEENEPLETPAPEPEPPTTNKWQLD 516
Query: 261 EYKKEVERKKLELDGEKETAP-----EEPGSP--AKSAPASPVQSPAKEAETKSPLVSPS 313
+ +V + +G + T P E GS A S S + P ++ +K+P +P
Sbjct: 517 NWLTKVSQPAAPPEGPRSTEPPRRHPESKGSSDSATSQEHSESKDPPPKSSSKAPR-APP 575
Query: 314 KSLEEGTKKTETSKAATTEPE-----TTQPEGVV-VNGREEEQTA-EEILSKGLSQMTTS 366
++ G + + S A P+ T QP+ V + R +T+ + GL +
Sbjct: 576 EAPHPGKRSCQKSPAQQEPPQRQTVGTKQPKKPVKASARAGSRTSLQGEREPGLLPYGSR 635
Query: 367 ADTDVDTSKDKTESVTSGPMSPEGSPSKSPSKKKKKFRT 405
T D K KT+ S E P+ PS +KKK ++
Sbjct: 636 DQTSKDKPKVKTKGRPRAAASNEPKPAVPPSSEKKKHKS 674
>gi|168229156 NFKB activating protein [Homo sapiens]
Length = 415
Score = 50.1 bits (118), Expect = 4e-06
Identities = 46/172 (26%), Positives = 73/172 (42%), Gaps = 24/172 (13%)
Query: 250 PFSQLTDQELEEYKKEVERKKLELDGEKETAPEEPG-SPAKSAPASPVQSPAKEAETKSP 308
P+ L D+E EE ++ + E GE APE G SP P S +P ++ E K
Sbjct: 113 PWPSLLDKEREESLRQKRLSERERIGELG-APEVWGLSPKNPEPDSDEHTPVEDEEPKKS 171
Query: 309 LVSPSKSLEEGTKKTETSKAATTEPETTQPEGVVVNGREEEQTAEEILSKGLSQMTTSAD 368
S S S EE KK+ SK R +++ ++ + + + +D
Sbjct: 172 TTSASTSEEEKKKKSSRSKE-----------------RSKKRRKKKSSKRKHKKYSEDSD 214
Query: 369 TDVDTSKDKTESVTSGPMSPEGSPSKSPSKKKKKFRTPSFLKKSKKKEKVES 420
+D D+ D +S + + +KKKK R+ + KK KK + ES
Sbjct: 215 SDSDSETD-----SSDEDNKRRAKKAKKKEKKKKHRSKKYKKKRSKKSRKES 261
Score = 30.0 bits (66), Expect = 4.1
Identities = 31/140 (22%), Positives = 58/140 (41%), Gaps = 20/140 (14%)
Query: 176 SCSEVTASSLIKEVLEMRNKIREQNRQDVKSAGPQSQLLASVIAEKSRSPSTESQLMSKG 235
S + + S K+ R+K R + R+ KS+ K + S +S S
Sbjct: 171 STTSASTSEEEKKKKSSRSKERSKKRRKKKSS-----------KRKHKKYSEDSDSDSDS 219
Query: 236 DEDTKDDSEETVPNPFSQLTDQELEEYKKEVERKKLELDGEKETAPEEPGSPAKSAPASP 295
+ D+ D+ + + + +E KK+ KK + K++ E S +K +
Sbjct: 220 ETDSSDEDNKR------RAKKAKKKEKKKKHRSKKYKKKRSKKSRKESSDSSSKESQEEF 273
Query: 296 VQSPAKE---AETKSPLVSP 312
+++P K+ AE S L+ P
Sbjct: 274 LENPWKDRTKAEEPSDLIGP 293
>gi|42518068 trans-golgi network protein 2 [Homo sapiens]
Length = 437
Score = 48.9 bits (115), Expect = 9e-06
Identities = 39/129 (30%), Positives = 64/129 (49%), Gaps = 13/129 (10%)
Query: 282 EEPGSPAKS--APASPVQSPAKE-AETKSPLVSPSKSLEEGTKKTETSKAATTEPETTQP 338
+ PG KS P +P SP+K AE ++P +P+KS E + ++S + E +T +
Sbjct: 48 QRPGGSTKSHPEPQTPKDSPSKSSAEAQTPEDTPNKSGAEAKTQKDSSNKSGAEAKTQK- 106
Query: 339 EGVVVNGREEEQTAEEILSKGLSQMTTSADTDVDTSKDKTESVTSGPMSPEGSPSKSPSK 398
G E QT ++ SK ++ T D+ T K E+ T PE SP++S ++
Sbjct: 107 -GSTSKSGSEAQTTKDSTSKSHPELQTPKDS---TGKSGAEAQT-----PEDSPNRSGAE 157
Query: 399 KKKKFRTPS 407
K + +PS
Sbjct: 158 AKTQKDSPS 166
Score = 35.8 bits (81), Expect = 0.075
Identities = 47/207 (22%), Positives = 83/207 (40%), Gaps = 19/207 (9%)
Query: 224 SPSTES-QLMSKGDEDTKDDSEETVPNPFSQLTDQELEEYKKEVERKKLELDGEKETAPE 282
SPS S + + D K +E S + E + K + E K+
Sbjct: 66 SPSKSSAEAQTPEDTPNKSGAEAKTQKDSSNKSGAEAKTQKGSTSKSGSEAQTTKD---- 121
Query: 283 EPGSPAKSAPA--SPVQSPAKE-AETKSPLVSPSKSLEEGTKKTETSKAATTEPETTQPE 339
S +KS P +P S K AE ++P SP++S E + ++ + +E +TT +
Sbjct: 122 ---STSKSHPELQTPKDSTGKSGAEAQTPEDSPNRSGAEAKTQKDSPSKSGSEAQTT--K 176
Query: 340 GVVVNGREEEQTAEEILSKGLSQMTTSAD------TDVDTSKDKTESVTSGPMSPEGSPS 393
V + QT ++ SK ++ T D + T KD + + P PS
Sbjct: 177 DVPNKSGADGQTPKDGSSKSGAEDQTPKDVPNKSGAEKQTPKDGSNKSGAEEQGPIDGPS 236
Query: 394 KSPSKKKKKFRTPSFLKKSKKKEKVES 420
KS ++++ +P+ + + K S
Sbjct: 237 KSGAEEQTSKDSPNKVVPEQPSRKDHS 263
Score = 32.7 bits (73), Expect = 0.63
Identities = 24/97 (24%), Positives = 41/97 (42%), Gaps = 6/97 (6%)
Query: 308 PLVSPSKSLEEGTKKTETSKAATTEPETTQPEGVVVNGREEEQTAEEILSKGLSQMTTSA 367
PL++ +E ++ +T P +Q G E QT ++ SK ++ T
Sbjct: 19 PLLATESVKQEEAGVRPSAGNVSTHPSLSQRPGGSTKSHPEPQTPKDSPSKSSAEAQTPE 78
Query: 368 DT------DVDTSKDKTESVTSGPMSPEGSPSKSPSK 398
DT + T KD + + + +GS SKS S+
Sbjct: 79 DTPNKSGAEAKTQKDSSNKSGAEAKTQKGSTSKSGSE 115
>gi|148596949 nucleolar and coiled-body phosphoprotein 1 [Homo
sapiens]
Length = 699
Score = 48.1 bits (113), Expect = 1e-05
Identities = 52/212 (24%), Positives = 84/212 (39%), Gaps = 20/212 (9%)
Query: 221 KSRSPSTESQLMSKGDEDTKDDSEETVPNPFSQLTDQELEEYKKEVERKKLELDGEKETA 280
K+ + ++ES + +D DD E+ P + + + K ++ K ++
Sbjct: 118 KAAAKASESSSSEESSDD--DDEEDQKKQPVQKGVKPQAKAAKAPPKKAKSSDSDSDSSS 175
Query: 281 PEEPGSPAK------------SAPASPVQSPAKEAETKSPLVSPSKSLEEGTKKTETSKA 328
+EP K AP P ++ K A K+ S S S + +E KA
Sbjct: 176 EDEPPKNQKPKITPVTVKAQTKAPPKPARAAPKIANGKAASSSSSSSSSSSSDDSEEEKA 235
Query: 329 ATTEPETTQPEGVVVNGREEEQTAEEILSKGLSQMTTSADTDVDTSKDKTESVTSGPMSP 388
A T P+ T P+ VV + + A K S +S+D + + K GP S
Sbjct: 236 AAT-PKKTVPKKQVV-AKAPVKAATTPTRKSSSSEDSSSDEEEEQKKPMKNK--PGPYSS 291
Query: 389 EGSPSKSPSKKKKKFRTPSFLKKSKKKEKVES 420
PS P KK + P K +K++ VES
Sbjct: 292 VPPPSAPPPKKSLGTQPPK--KAVEKQQPVES 321
Score = 44.7 bits (104), Expect = 2e-04
Identities = 59/260 (22%), Positives = 97/260 (37%), Gaps = 43/260 (16%)
Query: 192 MRNKIREQNRQDVKSAGPQSQLLASVIAEKSRSPSTESQLMSKGDEDTKDDS----EETV 247
M+NK + SA P + L + +K+ E Q + ED+ D+S EE
Sbjct: 282 MKNKPGPYSSVPPPSAPPPKKSLGTQPPKKA----VEKQQPVESSEDSSDESDSSSEEEK 337
Query: 248 PNPFSQLTDQELEEYKKEVERKKLELDGEKETAPEEPGSPAKSAPASPVQSPAKEAETKS 307
P + + + + + D + E+ +P+K A + S TKS
Sbjct: 338 KPPTKAVVSKATTKPPPAKKAAESSSDSSDSDSSEDDEAPSKPAGTTKNSSNKPAVTTKS 397
Query: 308 PLVSP--------------------SKSLEEGTKKTETSK----AATTEPETTQPEGVVV 343
P V P S S EE + +E K ATT+P+ T + +
Sbjct: 398 PAVKPAAAPKQPVGGGQKLLTRKADSSSSEEESSSSEEEKTKKMVATTKPKATAKAALSL 457
Query: 344 NGREEEQTAEEILSKGLSQMTTSADTDVDTSKD----KTESVTSGPMSPEGSPSKSPSKK 399
++ Q + + S S ++S + + TSK K + V G +PSK S K
Sbjct: 458 PAKQAPQGSRD--SSSDSDSSSSEEEEEKTSKSAVKKKPQKVAGG-----AAPSKPASAK 510
Query: 400 KKKFRTPSFLKKSKKKEKVE 419
K K + + E+ E
Sbjct: 511 KGKAESSNSSSSDDSSEEEE 530
Score = 41.6 bits (96), Expect = 0.001
Identities = 40/196 (20%), Positives = 73/196 (37%), Gaps = 11/196 (5%)
Query: 216 SVIAEKSRSPSTESQLMSKGDEDTKDDSEETVPNPFSQLTDQELEEYKKEVERKKLELDG 275
+V+++ + P + + + DS E P + K V K +
Sbjct: 343 AVVSKATTKPPPAKKAAESSSDSSDSDSSEDDEAPSKPAGTTKNSSNKPAVTTKSPAV-- 400
Query: 276 EKETAPEEPGSPAKSAPASPVQSPAKEAETKSPLVSPSKSLEEGTKKTETSKAATTEPET 335
+ AP++P + S + E E+ S +K + TK T+KAA + P
Sbjct: 401 KPAAAPKQPVGGGQKLLTRKADSSSSEEESSSSEEEKTKKMVATTKPKATAKAALSLPAK 460
Query: 336 TQPEG---------VVVNGREEEQTAEEILSKGLSQMTTSADTDVDTSKDKTESVTSGPM 386
P+G + EEE+T++ + K ++ A S K ++ +S
Sbjct: 461 QAPQGSRDSSSDSDSSSSEEEEEKTSKSAVKKKPQKVAGGAAPSKPASAKKGKAESSNSS 520
Query: 387 SPEGSPSKSPSKKKKK 402
S + S + K K K
Sbjct: 521 SSDDSSEEEEEKLKGK 536
Score = 33.5 bits (75), Expect = 0.37
Identities = 43/176 (24%), Positives = 70/176 (39%), Gaps = 24/176 (13%)
Query: 264 KEVERKKLELDGEKETAPEEP--GSPAKSA--PAS-----PVQSPAKEAETKSPLVSPSK 314
K+ ++K D E + EE G PAK A PA P ++ AK +E+ S S
Sbjct: 76 KKAKKKASSSDSEDSSEEEEEVQGPPAKKAAVPAKRVGLPPGKAAAKASESSSSEESSDD 135
Query: 315 SLEEGTKKTETSKAATTEPETTQ--PEGVVVNGREEEQTAEEILSKG----LSQMTTSAD 368
EE KK K + + + P+ + + + ++E+ K ++ +T A
Sbjct: 136 DDEEDQKKQPVQKGVKPQAKAAKAPPKKAKSSDSDSDSSSEDEPPKNQKPKITPVTVKAQ 195
Query: 369 TDVD------TSKDKTESVTSGPMSPEGSPSKSPSKKKKKFRTPSFLKKSKKKEKV 418
T K S S S S S+++K TP KK+ K++V
Sbjct: 196 TKAPPKPARAAPKIANGKAASSSSSSSSSSSSDDSEEEKAAATP---KKTVPKKQV 248
>gi|117935038 cylicin, basic protein of sperm head cytoskeleton 1
[Homo sapiens]
Length = 651
Score = 48.1 bits (113), Expect = 1e-05
Identities = 55/241 (22%), Positives = 101/241 (41%), Gaps = 17/241 (7%)
Query: 187 KEVLEMRNKIREQNRQDVKSAGPQSQLLASVIAEKSRSPSTESQLMSKGDEDTKDDSEET 246
K+ + + K+++ +++ P+S S A+ +R+ S + SK D+ KD + T
Sbjct: 345 KDTKKDKKKLKKDDKKKDTKKYPESTDTESGDAKDARNDSRNLKKASKNDDKKKDAKKIT 404
Query: 247 VPNPFSQLTDQELEEYKKEVERKK----LELDGEKETAPEEPGSPAKSAPASPVQSPAKE 302
FS ++ ELE + + + KK + D +K +E + A S P + K+
Sbjct: 405 ----FSTDSESELESKESQKDEKKDKKDSKTDNKKSVKNDEESTDADSEPKGDSKKGKKD 460
Query: 303 AETKSPLVSPSKSLEEGTKKTETSKAATTEPETTQPEGVVVNGREEEQTAEEILSKGLSQ 362
+ S ++ KK A +TE E+ +E++ +++ + K +
Sbjct: 461 EKK-----GKKDSKKDDKKKDAKKNAESTEMESDLELKKDKKHSKEKKGSKKDIKKDARK 515
Query: 363 MTTSADTDVDTSKDKTESVTSGPMSPEGSPSKSPSKK---KKKFRTPSFLKKSKKKEKVE 419
T S D + D S KT TS + + S+ K KKK + K E +E
Sbjct: 516 DTESTDAEFDES-SKTGFKTSTKIKGSDTESEESLYKPGAKKKIDESDGTSANSKMEGLE 574
Query: 420 S 420
S
Sbjct: 575 S 575
>gi|157738649 neurofilament, medium polypeptide 150kDa isoform 1
[Homo sapiens]
Length = 916
Score = 47.4 bits (111), Expect = 2e-05
Identities = 52/199 (26%), Positives = 79/199 (39%), Gaps = 22/199 (11%)
Query: 237 EDTKDDSEETVPNPFSQLTDQELEEYKKEVERKKLELDGEKETAPEEPGSPAKSAPASPV 296
ED K + EE + +L EE K+ E K+ E + E+E + +AP
Sbjct: 463 EDEKSEMEEALTAITEELAVSMKEEKKEAAEEKEEEPEAEEEEVAAKKSPVKATAPEVKE 522
Query: 297 QSPAKEAE------------TKSPLVSPSKSLEEGTKKTETSKAATTEPETTQPEGVVVN 344
+ KE E KS S +EG+ + E + E E + EG
Sbjct: 523 EEGEKEEEEGQEEEEEEDEGAKSDQAEEGGSEKEGSSEKEEGEQEEGETE-AEAEGEEAE 581
Query: 345 GREE---EQTAEEILSKGLSQMTTSADTDVDTSKDKTESVTSGPMSPEG-SP-SKSPSKK 399
+EE E+ +EE+ +K AD V+ + V P+ +G SP KSP ++
Sbjct: 582 AKEEKKVEEKSEEVATK----EELVADAKVEKPEKAKSPVPKSPVEEKGKSPVPKSPVEE 637
Query: 400 KKKFRTPSFLKKSKKKEKV 418
K K P + K K V
Sbjct: 638 KGKSPVPKSPVEEKGKSPV 656
Score = 46.2 bits (108), Expect = 6e-05
Identities = 61/238 (25%), Positives = 105/238 (44%), Gaps = 23/238 (9%)
Query: 190 LEMRNKIREQNRQDVKSAGPQSQL---LASVIAEKSRSPSTESQLMSKGDEDTKDDSEET 246
L++++K E+ ++ K +S++ L ++ E + S E + ++ E+ + EE
Sbjct: 446 LKVQHKFVEEIIEETKVEDEKSEMEEALTAITEELAVSMKEEKKEAAEEKEEEPEAEEEE 505
Query: 247 VPNPFSQLTDQELEEYKKEVERKKLELDGEKETAPEEPGSPAKSAPASPVQSPAKEAETK 306
V S + E KE E +K E +G++E E+ G AKS A S + + K
Sbjct: 506 VAAKKSPVKATAPEV--KEEEGEKEEEEGQEEEEEEDEG--AKSDQAEEGGSEKEGSSEK 561
Query: 307 SPLVSPSKSLEEGTKKT-ETSKAATTEPETTQPEGVVVNGREEEQTAEEILSKGLSQMTT 365
EEG ++ ET A E + E V EE T EE+++ +
Sbjct: 562 ----------EEGEQEEGETEAEAEGEEAEAKEEKKVEEKSEEVATKEELVADAKVEKPE 611
Query: 366 SADTDVDTSKDKTESVTSGPMSPEGSPSKSPSKK---KKKFRTPSFLKKSKKKEKVES 420
A + V S + + + P SP KSP K ++K ++P + KS +EK +S
Sbjct: 612 KAKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSP--VPKSPVEEKGKS 667
Score = 45.8 bits (107), Expect = 7e-05
Identities = 51/240 (21%), Positives = 93/240 (38%), Gaps = 17/240 (7%)
Query: 186 IKEVLEMRNKIREQNRQDVKSAGPQSQLLASVIAEKSRSPSTESQLMSKGDEDTKDDSEE 245
+KE + + Q ++ + G +S +EK S E +G+ + + + EE
Sbjct: 520 VKEEEGEKEEEEGQEEEEEEDEGAKSDQAEEGGSEKEGSSEKEEGEQEEGETEAEAEGEE 579
Query: 246 TVPNPFSQLTDQELEEYKKEVERKKLELDGEKETAPEE-----PGSPAKSA-----PASP 295
++++EE +EV K+ + K PE+ P SP + P SP
Sbjct: 580 AEAKE-----EKKVEEKSEEVATKEELVADAKVEKPEKAKSPVPKSPVEEKGKSPVPKSP 634
Query: 296 VQSPAKEAETKSPLVSPSKSLEEGTKKTETSKAATTE-PETTQPEGVVVNGREEEQTAEE 354
V+ K KSP+ KS + E K+ ++ P + + V EE ++
Sbjct: 635 VEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVSKSPVEEKAKSPVPKSPVEEAKSKA 694
Query: 355 ILSKGLSQMTTSADTDVDTSKDKTESVTSGPMS-PEGSPSKSPSKKKKKFRTPSFLKKSK 413
+ KG + + ++K E P PE ++SP K++ + K K
Sbjct: 695 EVGKGEQKEEEEKEVKEAPKEEKVEKKEEKPKDVPEKKKAESPVKEEAVAEVVTITKSVK 754
Score = 43.1 bits (100), Expect = 5e-04
Identities = 51/241 (21%), Positives = 94/241 (39%), Gaps = 18/241 (7%)
Query: 187 KEVLEMRNKIREQNRQDVKSAGPQSQLLASVIAEKSRSPSTESQLMSKGDEDTKDDSEET 246
KE E + + E ++V + + A + E+ E + +ED S++
Sbjct: 489 KEAAEEKEEEPEAEEEEVAAKKSPVKATAPEVKEEEGEKEEEEGQEEEEEEDEGAKSDQA 548
Query: 247 VPNPFSQLTDQELEEYKKEVERKKLELDGEKETAPEEPGSPAKSAPASPVQSPAKEAETK 306
+ E EE ++E + E +GE+ A EE V+ ++E TK
Sbjct: 549 EEGGSEKEGSSEKEEGEQEEGETEAEAEGEEAEAKEE----------KKVEEKSEEVATK 598
Query: 307 SPLVSPSKSLEEGTKKTETSKAATTEP-ETTQPEGVVVNGREEEQTAEEILSKGLSQMTT 365
LV+ +K + K+ K+ E ++ P+ V + + KG S +
Sbjct: 599 EELVADAKVEKPEKAKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPK 658
Query: 366 S-----ADTDVDTSKDKTESVTSGPMSP--EGSPSKSPSKKKKKFRTPSFLKKSKKKEKV 418
S + V S + ++ + P SP E K ++K +K++ K+EKV
Sbjct: 659 SPVEEKGKSPVSKSPVEEKAKSPVPKSPVEEAKSKAEVGKGEQKEEEEKEVKEAPKEEKV 718
Query: 419 E 419
E
Sbjct: 719 E 719
>gi|157738641 neurofilament, medium polypeptide 150kDa isoform 2
[Homo sapiens]
Length = 540
Score = 47.4 bits (111), Expect = 2e-05
Identities = 52/199 (26%), Positives = 79/199 (39%), Gaps = 22/199 (11%)
Query: 237 EDTKDDSEETVPNPFSQLTDQELEEYKKEVERKKLELDGEKETAPEEPGSPAKSAPASPV 296
ED K + EE + +L EE K+ E K+ E + E+E + +AP
Sbjct: 87 EDEKSEMEEALTAITEELAVSMKEEKKEAAEEKEEEPEAEEEEVAAKKSPVKATAPEVKE 146
Query: 297 QSPAKEAE------------TKSPLVSPSKSLEEGTKKTETSKAATTEPETTQPEGVVVN 344
+ KE E KS S +EG+ + E + E E + EG
Sbjct: 147 EEGEKEEEEGQEEEEEEDEGAKSDQAEEGGSEKEGSSEKEEGEQEEGETE-AEAEGEEAE 205
Query: 345 GREE---EQTAEEILSKGLSQMTTSADTDVDTSKDKTESVTSGPMSPEG-SP-SKSPSKK 399
+EE E+ +EE+ +K AD V+ + V P+ +G SP KSP ++
Sbjct: 206 AKEEKKVEEKSEEVATK----EELVADAKVEKPEKAKSPVPKSPVEEKGKSPVPKSPVEE 261
Query: 400 KKKFRTPSFLKKSKKKEKV 418
K K P + K K V
Sbjct: 262 KGKSPVPKSPVEEKGKSPV 280
Score = 46.2 bits (108), Expect = 6e-05
Identities = 61/238 (25%), Positives = 105/238 (44%), Gaps = 23/238 (9%)
Query: 190 LEMRNKIREQNRQDVKSAGPQSQL---LASVIAEKSRSPSTESQLMSKGDEDTKDDSEET 246
L++++K E+ ++ K +S++ L ++ E + S E + ++ E+ + EE
Sbjct: 70 LKVQHKFVEEIIEETKVEDEKSEMEEALTAITEELAVSMKEEKKEAAEEKEEEPEAEEEE 129
Query: 247 VPNPFSQLTDQELEEYKKEVERKKLELDGEKETAPEEPGSPAKSAPASPVQSPAKEAETK 306
V S + E KE E +K E +G++E E+ G AKS A S + + K
Sbjct: 130 VAAKKSPVKATAPEV--KEEEGEKEEEEGQEEEEEEDEG--AKSDQAEEGGSEKEGSSEK 185
Query: 307 SPLVSPSKSLEEGTKKT-ETSKAATTEPETTQPEGVVVNGREEEQTAEEILSKGLSQMTT 365
EEG ++ ET A E + E V EE T EE+++ +
Sbjct: 186 ----------EEGEQEEGETEAEAEGEEAEAKEEKKVEEKSEEVATKEELVADAKVEKPE 235
Query: 366 SADTDVDTSKDKTESVTSGPMSPEGSPSKSPSKK---KKKFRTPSFLKKSKKKEKVES 420
A + V S + + + P SP KSP K ++K ++P + KS +EK +S
Sbjct: 236 KAKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSP--VPKSPVEEKGKS 291
Score = 45.8 bits (107), Expect = 7e-05
Identities = 51/240 (21%), Positives = 93/240 (38%), Gaps = 17/240 (7%)
Query: 186 IKEVLEMRNKIREQNRQDVKSAGPQSQLLASVIAEKSRSPSTESQLMSKGDEDTKDDSEE 245
+KE + + Q ++ + G +S +EK S E +G+ + + + EE
Sbjct: 144 VKEEEGEKEEEEGQEEEEEEDEGAKSDQAEEGGSEKEGSSEKEEGEQEEGETEAEAEGEE 203
Query: 246 TVPNPFSQLTDQELEEYKKEVERKKLELDGEKETAPEE-----PGSPAKSA-----PASP 295
++++EE +EV K+ + K PE+ P SP + P SP
Sbjct: 204 AEAKE-----EKKVEEKSEEVATKEELVADAKVEKPEKAKSPVPKSPVEEKGKSPVPKSP 258
Query: 296 VQSPAKEAETKSPLVSPSKSLEEGTKKTETSKAATTE-PETTQPEGVVVNGREEEQTAEE 354
V+ K KSP+ KS + E K+ ++ P + + V EE ++
Sbjct: 259 VEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVSKSPVEEKAKSPVPKSPVEEAKSKA 318
Query: 355 ILSKGLSQMTTSADTDVDTSKDKTESVTSGPMS-PEGSPSKSPSKKKKKFRTPSFLKKSK 413
+ KG + + ++K E P PE ++SP K++ + K K
Sbjct: 319 EVGKGEQKEEEEKEVKEAPKEEKVEKKEEKPKDVPEKKKAESPVKEEAVAEVVTITKSVK 378
Score = 43.1 bits (100), Expect = 5e-04
Identities = 51/241 (21%), Positives = 94/241 (39%), Gaps = 18/241 (7%)
Query: 187 KEVLEMRNKIREQNRQDVKSAGPQSQLLASVIAEKSRSPSTESQLMSKGDEDTKDDSEET 246
KE E + + E ++V + + A + E+ E + +ED S++
Sbjct: 113 KEAAEEKEEEPEAEEEEVAAKKSPVKATAPEVKEEEGEKEEEEGQEEEEEEDEGAKSDQA 172
Query: 247 VPNPFSQLTDQELEEYKKEVERKKLELDGEKETAPEEPGSPAKSAPASPVQSPAKEAETK 306
+ E EE ++E + E +GE+ A EE V+ ++E TK
Sbjct: 173 EEGGSEKEGSSEKEEGEQEEGETEAEAEGEEAEAKEE----------KKVEEKSEEVATK 222
Query: 307 SPLVSPSKSLEEGTKKTETSKAATTEP-ETTQPEGVVVNGREEEQTAEEILSKGLSQMTT 365
LV+ +K + K+ K+ E ++ P+ V + + KG S +
Sbjct: 223 EELVADAKVEKPEKAKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPK 282
Query: 366 S-----ADTDVDTSKDKTESVTSGPMSP--EGSPSKSPSKKKKKFRTPSFLKKSKKKEKV 418
S + V S + ++ + P SP E K ++K +K++ K+EKV
Sbjct: 283 SPVEEKGKSPVSKSPVEEKAKSPVPKSPVEEAKSKAEVGKGEQKEEEEKEVKEAPKEEKV 342
Query: 419 E 419
E
Sbjct: 343 E 343
>gi|117414137 retinitis pigmentosa 1-like 1 [Homo sapiens]
Length = 2400
Score = 47.4 bits (111), Expect = 2e-05
Identities = 46/200 (23%), Positives = 87/200 (43%), Gaps = 22/200 (11%)
Query: 205 KSAGPQSQLLASVIAEKSRSPSTESQLMSKGDEDTKDDSEETVPNPF---SQLTDQELEE 261
K A P+++ + ++ E P +E + +E ++ +T P SQ ++E +
Sbjct: 1913 KEAQPETESVEALETEGEDEPESEGAEAQEAEEAAQEAEGQTQPESEVIESQEAEEEAQP 1972
Query: 262 YKKEVERKKLELDGEKETAPEEPGSPAKSAPASPVQSPAKEAETKSPLVSPSKSLEEGTK 321
++VE ++E++ ++ +P S AP + + +EAE ++ P E
Sbjct: 1973 ESEDVEALEVEVETQEAEGEAQPESEDVEAPEA--EGEMQEAEEEA---QPESDGVEAQP 2027
Query: 322 KTETSKAATTEPET------TQPEGVVVNGREEEQTAEEILSKGLSQMT------TSADT 369
K+E +A E ET QPE V E E+ A+E ++G Q S D
Sbjct: 2028 KSEGEEAQEVEGETQKTEGDAQPESDGVEAPEAEEEAQE--AEGEVQEAEGEAHPESEDV 2085
Query: 370 DVDTSKDKTESVTSGPMSPE 389
D ++ + + + G +PE
Sbjct: 2086 DAQEAEGEAQPESEGVEAPE 2105
Score = 43.5 bits (101), Expect = 4e-04
Identities = 50/208 (24%), Positives = 83/208 (39%), Gaps = 24/208 (11%)
Query: 198 EQNRQDVKSAGPQSQLLASVIAEKSRSPSTESQLM--SKGDE--DTKDDSEETVPNPFSQ 253
E N Q +AG S AE +P E + S+G E + + D++E +
Sbjct: 1811 EDNLQGEAAAGGDQDPGQSDGAEGIEAPEAEGEAQPESEGVEAPEAEGDAQEAEGEAQPE 1870
Query: 254 LTDQELEEYKKEVERKKLELD---GEKETAPEEPGSPAKSAP--ASPVQSPAKEAETKSP 308
D E E + E + + +++ E E PE G+ A A A P + ET+
Sbjct: 1871 SEDVEAPEAEGEAQPESEDVETPEAEWEVQPESEGAEAPEAEKEAQPETESVEALETEGE 1930
Query: 309 LVSPSKSLEEGTKKTETSKAATTEPETTQPEGVVVNGREEEQTAEEILSKGLSQMTTSAD 368
+ EG + E +AA TQPE V+ +E E+ A+ S+ + +
Sbjct: 1931 ----DEPESEGAEAQEAEEAAQEAEGQTQPESEVIESQEAEEEAQP-----ESEDVEALE 1981
Query: 369 TDVDTSKDKTESVTSGPMSPEGSPSKSP 396
+V+T + G PE ++P
Sbjct: 1982 VEVETQE------AEGEAQPESEDVEAP 2003
Score = 38.5 bits (88), Expect = 0.012
Identities = 47/192 (24%), Positives = 78/192 (40%), Gaps = 20/192 (10%)
Query: 219 AEKSRSPSTESQLMSKGDEDTKDDSEETVPNPFSQLTDQELEEYKKEVERKKLEL-DGEK 277
AE +P TE + + E + E P S+ + + E + + E + +E + E+
Sbjct: 2113 AEGIEAPETEGEAQPES-EGIEAPEAEGEAQPESEGVEAQDAEGEAQPESEGIEAQEAEE 2171
Query: 278 ETAPEEPG--SPAKSAPASP----VQSPAKEAETKSPLVSPSKSLEEGTKKTETSKAATT 331
E PE G +P A P +++P E E + L EG + E + A
Sbjct: 2172 EAQPELEGVEAPEAEGEAQPESEGIEAPEAEGEAQPEL--------EGVEAPEAEEEAQP 2223
Query: 332 EP---ETTQPEGVVVNGREEEQTAEEILSKGLSQMTTSADTDVDTSKDKTESVTSGPMSP 388
EP ET + EG E E E+ S +S ++ ++S E + P SP
Sbjct: 2224 EPEGVETPEAEGEAQPESEGETQGEKKGSPQVSLGDGQSEEASESSSPVPEDRPTPPPSP 2283
Query: 389 EG-SPSKSPSKK 399
G +P + P +
Sbjct: 2284 GGDTPHQRPGSQ 2295
Score = 37.4 bits (85), Expect = 0.026
Identities = 45/230 (19%), Positives = 89/230 (38%), Gaps = 20/230 (8%)
Query: 179 EVTASSLIKEVLEMRNKIREQNRQDVKSAGPQSQLLASVIAEKSRSPSTESQLMSKGDED 238
+V A + E E + + ++ +DV++ + ++ + + S E+Q S+G+E
Sbjct: 1976 DVEALEVEVETQEAEGEAQPES-EDVEAPEAEGEMQEAEEEAQPESDGVEAQPKSEGEEA 2034
Query: 239 TKDDSEETVPNPFSQ-----LTDQELEEYKKEVERKKLELDGEKETAPEEPGSPAKSAPA 293
+ + E +Q + E EE +E E + E +GE E+ + A
Sbjct: 2035 QEVEGETQKTEGDAQPESDGVEAPEAEEEAQEAEGEVQEAEGEAHPESEDVDAQEAEGEA 2094
Query: 294 SP----VQSPAKEAETKSPLVSPSKSLEEGTKKTETSKAATTEPETTQPEGVVVNGREEE 349
P V++P E E + EG + ET A E E + + E
Sbjct: 2095 QPESEGVEAPEAEGEAQK---------AEGIEAPETEGEAQPESEGIEAPEAEGEAQPES 2145
Query: 350 QTAEEILSKGLSQMTTSADTDVDTSKDKTESVTSGPMSPEGSPSKSPSKK 399
+ E ++G +Q S + ++++ + G +PE P +
Sbjct: 2146 EGVEAQDAEGEAQ-PESEGIEAQEAEEEAQPELEGVEAPEAEGEAQPESE 2194
Score = 33.5 bits (75), Expect = 0.37
Identities = 33/141 (23%), Positives = 50/141 (35%), Gaps = 12/141 (8%)
Query: 244 EETVPNPFSQLTDQELEEYKKEV-----------ERKKLELDGEKETAPEEPGSPAKSAP 292
EE P L + LEE KE E + K + ++P ++
Sbjct: 1375 EEVKEGPEGGLQGEALEEGLKEEGLPEEGSVHGQELSEASSPDGKGSQEDDPVQEEEAGR 1434
Query: 293 ASPVQSPAKEAETKSPLVSPSKSLEEGTKKTETSKAATTEPETTQPEGVVVNGREEEQT- 351
AS P T+ P PS E +E + EP +P G + G+E Q
Sbjct: 1435 ASASAEPCPAEGTEEPTEPPSHLSETDPSASERQSGSQLEPGLEKPPGATMMGQEHTQAQ 1494
Query: 352 AEEILSKGLSQMTTSADTDVD 372
+ ++ S + SA D D
Sbjct: 1495 PTQGAAERSSSVACSAALDCD 1515
Score = 32.0 bits (71), Expect = 1.1
Identities = 42/174 (24%), Positives = 68/174 (39%), Gaps = 30/174 (17%)
Query: 209 PQSQLLASVIAEKSRSPSTESQLMSKGDEDTKDDSEETVPN------PFSQLTDQELEEY 262
P+S+++ S AE+ P +E + + +T++ E P P ++ QE EE
Sbjct: 1956 PESEVIESQEAEEEAQPESEDVEALEVEVETQEAEGEAQPESEDVEAPEAEGEMQEAEEE 2015
Query: 263 ------------KKEVERKKLELDGE--KETAPEEPGSPAKSAPAS---------PVQSP 299
K E E + E++GE K +P S AP + VQ
Sbjct: 2016 AQPESDGVEAQPKSEGEEAQ-EVEGETQKTEGDAQPESDGVEAPEAEEEAQEAEGEVQEA 2074
Query: 300 AKEAETKSPLVSPSKSLEEGTKKTETSKAATTEPETTQPEGVVVNGREEEQTAE 353
EA +S V ++ E ++E +A E E + EG+ E E E
Sbjct: 2075 EGEAHPESEDVDAQEAEGEAQPESEGVEAPEAEGEAQKAEGIEAPETEGEAQPE 2128
>gi|118498359 ribosomal L1 domain containing 1 [Homo sapiens]
Length = 490
Score = 47.0 bits (110), Expect = 3e-05
Identities = 54/223 (24%), Positives = 84/223 (37%), Gaps = 32/223 (14%)
Query: 210 QSQLLASVIAEKSRSPSTESQLMSKGDEDTKDDSEETVPNPFSQLTDQELEEYKKEVERK 269
+S L V EKS + S +S DE TK L + KKE RK
Sbjct: 246 ESVKLLFVKTEKSAALPIFSSFVSNWDEATKRSL---------------LNKKKKEARRK 290
Query: 270 KLELDGEKETAPEEPGSPAKSAPA----SPVQSPAKEAETKSPLVSPSKSLEEGTKKTET 325
+ E + EK+ ++ A+ + V + + K P ++ E G KK
Sbjct: 291 RRERNFEKQKERKKKRQQARKTASVLSKDDVAPESGDTTVKKPESKKEQTPEHGKKKRGR 350
Query: 326 SKA---ATTEPETTQPEGVVVNGREEEQTAEEILSKGLSQMTTSADTDVDTSKDKTESVT 382
KA AT E E P+ V + + EI + + + + T + K
Sbjct: 351 GKAQVKATNESEDEIPQLVPIGKKTPANEKVEIQKHATGKKSPAKSPNPSTPRGKKRKAL 410
Query: 383 SGPMSPEG----SPSKSPSKKKK------KFRTPSFLKKSKKK 415
+P+ +P KSP KK K K ++PS KK ++
Sbjct: 411 PASETPKAAESETPGKSPEKKPKIKEEAVKEKSPSLGKKDARQ 453
>gi|155030232 proline, glutamic acid and leucine rich protein 1 [Homo
sapiens]
Length = 1130
Score = 46.6 bits (109), Expect = 4e-05
Identities = 47/200 (23%), Positives = 75/200 (37%), Gaps = 31/200 (15%)
Query: 220 EKSRSPSTESQLMSKGDEDTKDDSEETVPNPFSQLTDQELEEYKKEVERKKLELDGEKET 279
E+ E + + +E+ + EE + + ++E EE+++E E ++ EL+ E+E
Sbjct: 889 EEEEEEEEEEEEEEEEEEEEDFEEEEEDEEEYFEEEEEEEEEFEEEFEEEEGELEEEEEE 948
Query: 280 APEEP----------------GSPAKSAPASPVQSPAKEAETKSPLVSPSKSLEEG---- 319
EE G + AP P PA P V P E G
Sbjct: 949 EDEEEEEELEEVEDLEFGTAGGEVEEGAPPPPTLPPALPPPESPPKVQPEPEPEPGLLLE 1008
Query: 320 --TKKTETSKAATTEPETTQPEGVVVNG---REEEQTA-----EEILSKGLSQMTTSADT 369
TE + A T P T PE + G RE E A +E++ + S T +
Sbjct: 1009 VEEPGTEEERGADTAP-TLAPEALPSQGEVEREGESPAAGPPPQELVEEEPSAPPTLLEE 1067
Query: 370 DVDTSKDKTESVTSGPMSPE 389
+ + DK + P E
Sbjct: 1068 ETEDGSDKVQPPPETPAEEE 1087
Score = 28.9 bits (63), Expect = 9.1
Identities = 26/100 (26%), Positives = 44/100 (44%), Gaps = 15/100 (15%)
Query: 181 TASSLIKEVLEMRNKIREQNRQDVKSAGPQSQLLASVIAEKSRSPSTESQLMSKGDEDTK 240
TA +L E L + ++ + +AGP Q L PS L+ +E+T+
Sbjct: 1022 TAPTLAPEALPSQGEVEREGESP--AAGPPPQELVE------EEPSAPPTLL---EEETE 1070
Query: 241 DDSEETVPNPFSQLTDQELEEYKKEVERKKLELDGEKETA 280
D S++ P P + EE + E E + L+ + +TA
Sbjct: 1071 DGSDKVQPPPETPAE----EEMETETEAEALQEKEQDDTA 1106
>gi|157738619 smoothelin-like 1 [Homo sapiens]
Length = 512
Score = 45.4 bits (106), Expect = 9e-05
Identities = 47/212 (22%), Positives = 81/212 (38%), Gaps = 18/212 (8%)
Query: 198 EQNRQDVKSAGPQSQLLASVIAEKSRSP--STESQLMSKGDEDTKDDSEETVPNPFSQLT 255
E+ + + K A P+S A P + E + ++ +E P + T
Sbjct: 153 EKQKAEEKEAKPESGQKADANDRDKPEPKATVEEEDAKTASQEETGQRKECSTEPKEKAT 212
Query: 256 DQELEEYKKEVERKKLELDGEKETAPEEPGSPAKSAPASPVQSPAKEAETKSPLVSPSKS 315
D+E + E +K ++ E + P+EP ++ + ++ AKE ++
Sbjct: 213 DEEAK-----AESQKAVVEDEAKAEPKEPDGKEEAKHGAKEEADAKEE------AEDAEE 261
Query: 316 LEEGTKKTETSKAATTEPETTQPEGVVVNGREEEQTAEEILSKGLSQMTTSADTDVDTSK 375
E G+ E + EPE G V E+ E +G + T D S
Sbjct: 262 AEPGSPSEEQEQDVEKEPE----GGAGVIPSSPEEWPESPTGEGHNLSTDGLGPDCVASG 317
Query: 376 DKTESVT-SGPMSPEGSPSKSPSKKKKKFRTP 406
+ S + S P SP +SPS +KK + P
Sbjct: 318 QTSPSASESSPSDVPQSPPESPSSGEKKEKAP 349
Score = 38.5 bits (88), Expect = 0.012
Identities = 46/191 (24%), Positives = 71/191 (37%), Gaps = 13/191 (6%)
Query: 222 SRSPSTESQLMSKGD-EDTKDDSEETVPNPFSQLTDQELEEY--KKEVERKKLELDGEKE 278
+ P TES K ED + N ++ + E K++ E + + DGEKE
Sbjct: 61 NEGPPTESGKQEKAPAEDGMSAELQGEANGLDEVKVESQREAGGKEDAEAELKKEDGEKE 120
Query: 279 TAPEEPGSPAKSAPASPVQSPAKEAETK-SPLVSPSKSLEEGTKKTETSKAATT------ 331
GS + +S KEAE K S L S + EE K E+ + A
Sbjct: 121 ETTV--GSQEMTGRKEETKSEPKEAEEKESTLASEKQKAEEKEAKPESGQKADANDRDKP 178
Query: 332 EPETTQPEGVVVNGREEEQTAEEILSKGLSQMTTSADTDVDTSKDKTE-SVTSGPMSPEG 390
EP+ T E +EE + S + T + ++ K E + P P+G
Sbjct: 179 EPKATVEEEDAKTASQEETGQRKECSTEPKEKATDEEAKAESQKAVVEDEAKAEPKEPDG 238
Query: 391 SPSKSPSKKKK 401
K++
Sbjct: 239 KEEAKHGAKEE 249
>gi|7662238 apoptotic chromatin condensation inducer 1 [Homo
sapiens]
Length = 1341
Score = 45.1 bits (105), Expect = 1e-04
Identities = 54/260 (20%), Positives = 111/260 (42%), Gaps = 31/260 (11%)
Query: 162 SKEQDHFLISPKGVSC--SEVTASSLIKEVLEM-RNKIREQNRQDVKSAGPQSQLLASVI 218
S E + +I P+GV+ SSL + LE+ R+ R+ + + +
Sbjct: 166 SAESEDEMIHPEGVASLLPPDFQSSLERPELELSRHSPRKSSSISEEKGDSDDEKPRKGE 225
Query: 219 AEKSRSPSTESQLMSKGDEDTKDDSEETVPNPFSQL-TDQELEEYKKEVERKKLELDGEK 277
SR + +S+G + +++ ++ P+ ++ D+ L+ ++E E ++ E D E+
Sbjct: 226 RRSSRVRQARAAKLSEGSQPAEEEEDQETPSRNLRVRADRNLKTEEEEEEEEEEEEDDEE 285
Query: 278 ETAPEEPGSPAKSAPASPVQSPAKEAETKSPLVSPSKSLEEGTKKTETSKAATTEPETTQ 337
E +E G ++ AP + KE + P V P + ++E K +Q
Sbjct: 286 EEGDDE-GQKSREAP---ILKEFKEEGEEIPRVKPEEMMDERPK------------TRSQ 329
Query: 338 PEGVVVNGREEEQTAEEILSKGLSQMTTSADTDVDTSKDKTESVTSGPMSPEGSPSKSPS 397
+ V+ G ++ EE L++ + + E T+ P+ E KS
Sbjct: 330 EQEVLERGGRFTRSQEEARKSHLAR-----------QQQEKEMKTTSPLEEEEREIKSSQ 378
Query: 398 KKKKKFRTPSFLKKSKKKEK 417
K+K ++PS + ++ ++K
Sbjct: 379 GLKEKSKSPSPPRLTEDRKK 398
Score = 29.6 bits (65), Expect = 5.4
Identities = 25/87 (28%), Positives = 41/87 (47%), Gaps = 6/87 (6%)
Query: 333 PETTQPEGVVVNGREEEQTAEEILSKGLSQMTTSADTDVDTSKDKTESVTSGPMSPEGSP 392
P P+ RE+E+ E ++ +M T + D+ + V GP S
Sbjct: 1123 PPVQPPQHPRAEQREQERAVREQWAEREREMERRERTRSEREWDR-DKVREGPRSR---- 1177
Query: 393 SKSPSKKKKKFRTPSFLKKSKKKEKVE 419
S+S +++K+ R S KKS+KKEK +
Sbjct: 1178 SRSRDRRRKE-RAKSKEKKSEKKEKAQ 1203
>gi|153945728 microtubule-associated protein 1B [Homo sapiens]
Length = 2468
Score = 45.1 bits (105), Expect = 1e-04
Identities = 52/197 (26%), Positives = 82/197 (41%), Gaps = 12/197 (6%)
Query: 215 ASVIAEKSRSPSTESQLMSKGDEDTKDDSEE-TVPNPFSQLTDQELEEYKKEVERKKLEL 273
AS I +++ +ES+ + +E+ +D EE T + ++Q T + E E
Sbjct: 1082 ASSIHDETLPGGSESEATASDEENREDQPEEFTATSGYTQSTIEISSEPTPMDEMSTPRD 1141
Query: 274 DGEKETAPEEPGSPAKS-APASPVQSPAKEAETKSPL-VSPSKSLEEGTKKTETS-KAAT 330
ET EE SP++ + +S E P V+P EG+K T K
Sbjct: 1142 VMSDETNNEETESPSQEFVNITKYESSLYSQEYSKPADVTPLNGFSEGSKTDATDGKDYN 1201
Query: 331 TEPETTQPEGVVVNGREEEQTAEEILSKGL-SQMTTSADTDVDTSKDKTESVTSGPMSPE 389
T P + EE++ + L S++ S D+ KD +V+S +SP
Sbjct: 1202 ASASTISPP----SSMEEDKFSRSALRDAYCSEVKASTTLDI---KDSISAVSSEKVSPS 1254
Query: 390 GSPSKSPSKKKKKFRTP 406
SPS SPS +TP
Sbjct: 1255 KSPSLSPSPPSPLEKTP 1271
Score = 42.4 bits (98), Expect = 8e-04
Identities = 40/184 (21%), Positives = 69/184 (37%), Gaps = 8/184 (4%)
Query: 239 TKDDSEETVPNPFSQLTDQELEEYKKEVERKKLELDGEKETAPEEPGSPAKSAPASPVQS 298
T+ D VP P + T + +E + + K E + + V+
Sbjct: 517 TQKDLTGQVPTPVVKQTKLKQRADSRESLKPAAKPLPSKSVRKESKEETPEVTKVNHVEK 576
Query: 299 PAKEAETKSPLVSPSKSLEEGTKKTETSKAATTEPETTQPEGVVVNGREEEQTAEEILSK 358
P K + +V K + KTET + T + ++ E V E+ A ++ K
Sbjct: 577 PPKVESKEKVMVKKDKPI-----KTETKPSVTEKEVPSKEEPSPVKAEVAEKQATDVKPK 631
Query: 359 GLSQMTTSADTDV---DTSKDKTESVTSGPMSPEGSPSKSPSKKKKKFRTPSFLKKSKKK 415
+ T +T V D ++K + + +P K K KK+ K+ KK+
Sbjct: 632 AAKEKTVKKETKVKPEDKKEEKEKPKKEVAKKEDKTPIKKEEKPKKEEVKKEVKKEIKKE 691
Query: 416 EKVE 419
EK E
Sbjct: 692 EKKE 695
Score = 40.4 bits (93), Expect = 0.003
Identities = 42/179 (23%), Positives = 80/179 (44%), Gaps = 15/179 (8%)
Query: 216 SVIAEKSRSPSTESQLMSKGDEDTKDDSEETVPNPFSQLTDQELEEYKKEVERKKLELDG 275
S AE + + ++ GD+ ++D +E + ++ +++E +E K + ++ E +
Sbjct: 977 SAKAEADAYIREKRESVASGDDRAEEDMDEAIEKGEAEQSEEEADEEDKAEDAREEEYEP 1036
Query: 276 EKETAPEEPGSPA-KSAPASPVQ-------SPAKEAETKSPLVSPSKSLEEGTKKTETSK 327
EK A + + K+A A + +P K+ +SP P+ S+ + T +
Sbjct: 1037 EKMEAEDYVMAVVDKAAEAGGAEEQYGFLTTPTKQLGAQSPGREPASSIHDETLPGGSES 1096
Query: 328 AATTEPETT---QPEGVVVNGREEEQTAEEILSK--GLSQMTTSADTDVD-TSKDKTES 380
AT E QPE + T EI S+ + +M+T D D T+ ++TES
Sbjct: 1097 EATASDEENREDQPEEFTATSGYTQSTI-EISSEPTPMDEMSTPRDVMSDETNNEETES 1154
Score = 36.6 bits (83), Expect = 0.044
Identities = 42/222 (18%), Positives = 87/222 (39%), Gaps = 28/222 (12%)
Query: 219 AEKSRSPSTESQLMSKGDEDTKDDSEETVPNPFSQLTDQELEEYKKEVERKKLELDGEKE 278
A K ++ E+++ + ++ K+ ++ V + ++ E+ KKE +K+++ + +KE
Sbjct: 632 AAKEKTVKKETKVKPEDKKEEKEKPKKEVAKKEDKTPIKKEEKPKKEEVKKEVKKEIKKE 691
Query: 279 TAPEEPGSPAKSAPASPVQSPAKEAETKSPLVS-----------PSKSLEEGTKKTETSK 327
E K P V+ K+ E K P + + T +E K
Sbjct: 692 EKKEPKKEVKKETPPKEVKKEVKKEEKKEVKKEEKEPKKEIKKLPKDAKKSSTPLSEAKK 751
Query: 328 AATTEP------ETTQPEGVVVNGREEEQTAEEILSKGLSQMTTSADTDVDTSKDKTESV 381
A +P E+ + + V +E+ + I +G + +A T +
Sbjct: 752 PAALKPKVPKKEESVKKDSVAAGKPKEKGKIKVIKKEGKAAEAVAAAVG-------TGAT 804
Query: 382 TSGPMSPEG----SPSKSPSKKKKKFRTPSFLKKSKKKEKVE 419
T+ M+ G P+K ++ +P L K ++ K E
Sbjct: 805 TAAVMAAAGIAAIGPAKELEAERSLMSSPEDLTKDFEELKAE 846
Score = 33.9 bits (76), Expect = 0.28
Identities = 34/130 (26%), Positives = 55/130 (42%), Gaps = 23/130 (17%)
Query: 269 KKLELDGEKETAPEEPGSPAKSAP-------------ASPVQSPAKEAETKSPLVSPSKS 315
K L+ D +++T ++PG+ KS+ ASP + KE+ K V+ K
Sbjct: 2233 KALKKDLKEKTKTKKPGTKTKSSSPVKKSDGKSKPLAASPKPAGLKESSDKVSRVASPK- 2291
Query: 316 LEEGTKKTETSKAATTEPETTQPEGVVVNGREEEQTAEEILSKGLSQMTTSADTDVDTSK 375
KK KAA TT PE G E+++ + + S+ +A T+K
Sbjct: 2292 -----KKESVEKAA---KPTTTPEVKAARGEEKDKETKNAANASASKSAKTATAGPGTTK 2343
Query: 376 -DKTESVTSG 384
K+ +V G
Sbjct: 2344 TTKSSAVPPG 2353
>gi|189181724 proteoglycan 4 isoform D [Homo sapiens]
Length = 1270
Score = 44.7 bits (104), Expect = 2e-04
Identities = 47/212 (22%), Positives = 83/212 (39%), Gaps = 14/212 (6%)
Query: 221 KSRSPSTESQLMSKGDEDTKDDSEETVPNPFSQL----TDQELEEYKKEVERKKLELDGE 276
K +P+T + + + ET P S++ T +E K + EL E
Sbjct: 690 KETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAE 749
Query: 277 K-----ETAPEEPGSPAKSAPASP---VQSPAKEAETKSPLVSPSKSLEEGTKKTETSKA 328
E +P+EPG P PA+ + + AK+ T+ L + ++ K T+ +
Sbjct: 750 PTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRTTPETTTAAPKMTK--ET 807
Query: 329 ATTEPETTQPEGVVVNGREEEQTAEEILSKGLSQMTTSADTDVDTSKDKTESVTSGPMSP 388
ATT +TT+ + + T ++ ++ + T+ T+ KT + T P
Sbjct: 808 ATTTEKTTESKITATTTQVTSTTTQDTTPFKITTLKTTTLAPKVTTTKKTITTTEIMNKP 867
Query: 389 EGSPSKSPSKKKKKFRTPSFLKKSKKKEKVES 420
E + K TP K +K +K S
Sbjct: 868 EETAKPKDRATNSKATTPKPQKPTKAPKKPTS 899
Score = 41.6 bits (96), Expect = 0.001
Identities = 35/133 (26%), Positives = 52/133 (39%), Gaps = 8/133 (6%)
Query: 277 KETAPEEPGSPAKSAPASPVQSPAKEAETKSPLVSPSKSLEEGTKKTETS----KAATTE 332
KE AP P PA + P + KE +P K L T K TS K A T
Sbjct: 629 KEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTT 688
Query: 333 PETTQP----EGVVVNGREEEQTAEEILSKGLSQMTTSADTDVDTSKDKTESVTSGPMSP 388
P+ T P E ++ T E S+++T T T+ K+ ++ +S
Sbjct: 689 PKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSA 748
Query: 389 EGSPSKSPSKKKK 401
E +P + K+
Sbjct: 749 EPTPKALENSPKE 761
Score = 41.2 bits (95), Expect = 0.002
Identities = 39/149 (26%), Positives = 53/149 (35%), Gaps = 16/149 (10%)
Query: 263 KKEVERKKLELDGEKETAPEEPGSPAKSAPASPVQSPAKEAETKSPLVSPSKSLEEGTKK 322
K E K L KE P P PA + P P + K A T +P+ + T
Sbjct: 200 KAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTP 259
Query: 323 TETSKAATTEPETTQPEGVVVNGREEEQTAEEILSKGLSQMTTSADTDVDTSKDKTESVT 382
E + T EP T P ++ A + T SA T T K E
Sbjct: 260 KEPAPTTTKEPAPTTP----------KEPAPTTTKEPAPTTTKSAPT---TPK---EPAP 303
Query: 383 SGPMSPEGSPSKSPSKKKKKFRTPSFLKK 411
+ P P + K P+ K TP+ K+
Sbjct: 304 TTPKKPAPTTPKEPAPTTPKEPTPTTPKE 332
Score = 39.3 bits (90), Expect = 0.007
Identities = 60/273 (21%), Positives = 98/273 (35%), Gaps = 25/273 (9%)
Query: 158 TLRVSKEQDHFLISPKGVSCSEVTASSLIKEVLEMRNKIREQNRQDVKSAGPQSQLLASV 217
+L V+KE + K + + S+ KE + + + K P S++LA
Sbjct: 141 SLTVNKETT---VETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAK- 196
Query: 218 IAEKSRSPSTESQLMSKGDE-DTKDDSEETVPNPFSQLTDQELEE--YKKEVERKKLELD 274
P+ +++ +KG T + T P + T +E K K
Sbjct: 197 -------PTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAP 249
Query: 275 GEKETAPEEPGSPAKSAPASPVQSPAKE---AETKSPLVSPSKSLEEGTKK---TETSKA 328
++AP P PA + P + KE TK P + +KS K+ T K
Sbjct: 250 TTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKP 309
Query: 329 ATTEPE----TTQPEGVVVNGREEEQTAEEILSKGLSQMTTSADTDVDTSKDKTESVTSG 384
A T P+ TT E +E T +E + +A + K + T+
Sbjct: 310 APTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTT- 368
Query: 385 PMSPEGSPSKSPSKKKKKFRTPSFLKKSKKKEK 417
P P + +K PS K P+ K + K
Sbjct: 369 PKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTK 401
Score = 39.3 bits (90), Expect = 0.007
Identities = 36/137 (26%), Positives = 50/137 (36%), Gaps = 11/137 (8%)
Query: 277 KETAPEEPGSPAKSAPASPVQSPAKEAETKSPLVSPSKSLEEGTKKTETSKAATT--EPE 334
KE AP P PA +AP P + KE +P + +E + T A TT
Sbjct: 338 KEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAP 397
Query: 335 TTQPEGVVVNGREEEQTAEEILSKGLSQMTTSADTDVDTSKDKTESVTSGPMSPEGSPSK 394
TT E + T +E TT+ + T K E + P P + K
Sbjct: 398 TTTKEPAPTTTKSAPTTPKE------PSPTTTKEPAPTTPK---EPAPTTPKKPAPTTPK 448
Query: 395 SPSKKKKKFRTPSFLKK 411
P+ K P+ KK
Sbjct: 449 EPAPTTPKEPAPTTTKK 465
Score = 39.3 bits (90), Expect = 0.007
Identities = 45/211 (21%), Positives = 71/211 (33%), Gaps = 24/211 (11%)
Query: 205 KSAGPQSQLLASVIAEKSRSPSTESQLMSKGDED----TKDDSEETVPNPFSQLTDQELE 260
K P + + K +P+T +L E T + T P + T +E
Sbjct: 464 KKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPT 523
Query: 261 EYKKEVERKKLELDGEKETAPEEPGSPAKSAPASPVQSPAKEAETKSPLVSPSKSLEEGT 320
E K AP P PA + P P + KE +P + + +GT
Sbjct: 524 PTTPEEPAPTTP----KAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTP-KETAPTTPKGT 578
Query: 321 KKTETSKAATTEPETTQPEGVVVNGREEEQTAEEILSKGLSQMTTSADTDVDTSKDKTES 380
T + A T P+ P+ + +E +T+ D T+ T
Sbjct: 579 APTTLKEPAPTTPKKPAPKELAPTTTKE-------------PTSTTCDKPAPTTPKGTAP 625
Query: 381 VTSGPMSPEGSPSKSPSKKKKKFRTPSFLKK 411
T P P + K P+ K P+ LK+
Sbjct: 626 TT--PKEPAPTTPKEPAPTTPKGTAPTTLKE 654
Score = 37.0 bits (84), Expect = 0.034
Identities = 51/231 (22%), Positives = 88/231 (38%), Gaps = 22/231 (9%)
Query: 171 SPK--GVSCSEVTASSLIKEVLEMRNKIREQNRQ---DVKSAGPQSQLLASVIAEKSRSP 225
SPK GV ++ A++ + ++K E++ + + +A P+ + EK+
Sbjct: 758 SPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEKT--- 814
Query: 226 STESQLMSKGDEDTKDDSEETVPNPFSQLTDQELEEYKKEVERKKLELDGEKETAPEEPG 285
TES++ + + T +++T P + L L K KK E PEE
Sbjct: 815 -TESKITATTTQVTSTTTQDTTPFKITTLKTTTLAP--KVTTTKKTITTTEIMNKPEETA 871
Query: 286 SPAKSAPASPVQSPAKEAETKSPLVSPSKSLEEGTKKTETSKAATTEPETTQPEGVVVNG 345
P A S +P + TK+P S TKK +T T P +
Sbjct: 872 KPKDRATNSKATTPKPQKPTKAPKKPTS------TKKPKTMPRVRKPKTTPTPRKMTSTM 925
Query: 346 REEEQTAEEILSKGLSQMTTSADTDVDTSKDKTESVTSGPMSPEGSPSKSP 396
E T+ +++ + Q TT + T K V G+ ++P
Sbjct: 926 PELNPTSR--IAEAMLQTTTRPN---QTPNSKLVEVNPKSEDAGGAEGETP 971
Score = 36.6 bits (83), Expect = 0.044
Identities = 34/148 (22%), Positives = 56/148 (37%), Gaps = 7/148 (4%)
Query: 277 KETAPEEPGSPAKSAPASPVQSPAKEAETKSPLVSPSKSLEEGTKKTETSKAATTEPETT 336
K T P+ + SP + AK + L S + +E + T+ TT
Sbjct: 98 KVTTPDTSTTQHNKVSTSPKITTAKPINPRPSLPPNSDTSKETSLTVNKETTVETKETTT 157
Query: 337 QPEGVVVNGREEEQTAEEILSKGLSQMTTSADTDVDTSK--DKTESVTSG-----PMSPE 389
+ +G+E+ +A+E S + A T +K K E+ T G P P
Sbjct: 158 TNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPT 217
Query: 390 GSPSKSPSKKKKKFRTPSFLKKSKKKEK 417
+ K P+ K TP+ +K + K
Sbjct: 218 PTTPKEPASTTPKEPTPTTIKSAPTTPK 245
Score = 36.6 bits (83), Expect = 0.044
Identities = 38/144 (26%), Positives = 51/144 (35%), Gaps = 9/144 (6%)
Query: 277 KETAPEEPGSPAKSAPASPVQSPAKEAETKSPLVSPSKSLEEGTKKTETSKAATTEPETT 336
K TAP PA + P P TK P + S T K ET+ EP T
Sbjct: 645 KGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPK-ETAPTTPKEPAPT 703
Query: 337 QPEGVVVNGREEEQTAEEILSKGLSQMTTSADTDVDTSKDKTESVTSGPMSP---EGSPS 393
P+ E T S+ + TT T + S D++ S +P E SP
Sbjct: 704 TPKKPAPTTPE---TPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPK 760
Query: 394 KS--PSKKKKKFRTPSFLKKSKKK 415
+ P+ K P +K K
Sbjct: 761 EPGVPTTKTPAATKPEMTTTAKDK 784
Score = 30.0 bits (66), Expect = 4.1
Identities = 28/138 (20%), Positives = 48/138 (34%), Gaps = 10/138 (7%)
Query: 279 TAPEEPG-----SPAKSAPASPVQSPAKEAETKSPLVSPSKSLEEGTKKTETSKAATTEP 333
T P+EP PA + P P + K+ +P P+ + + T T K A T P
Sbjct: 413 TTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTP-KEPAPTTPKEPAPTTTKKPAPTTP 471
Query: 334 ETTQPEGVVVNGREEEQTAEEILSKGLSQMTTSADTDVDTSKDKTESVTSGPMSPEGSPS 393
+ P +E T + L+ + + E + P P +
Sbjct: 472 KEPAP----TTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTP 527
Query: 394 KSPSKKKKKFRTPSFLKK 411
+ P+ K P+ K+
Sbjct: 528 EEPAPTTPKAAAPNTPKE 545
Score = 30.0 bits (66), Expect = 4.1
Identities = 28/139 (20%), Positives = 48/139 (34%), Gaps = 10/139 (7%)
Query: 279 TAPEEPG-----SPAKSAPASPVQSPAKEAETKSPLVSPSKSLEEGTKKTETSKAATTEP 333
T P++P PA + P P + K+ +P P+ + + T T K T P
Sbjct: 437 TTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTP-KEPAPTTPKETAPTTPKKLTPTTP 495
Query: 334 ETTQPEGVVVNGREEEQTAEEILSKGLSQMTTSADTDVDTSKDKTESVTSGPMSPEGSPS 393
E P + T E L+ + T + + + P P +
Sbjct: 496 EKLAP----TTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTP 551
Query: 394 KSPSKKKKKFRTPSFLKKS 412
K P+ K P+ K++
Sbjct: 552 KEPAPTTPKEPAPTTPKET 570
>gi|189181722 proteoglycan 4 isoform C [Homo sapiens]
Length = 1311
Score = 44.7 bits (104), Expect = 2e-04
Identities = 47/212 (22%), Positives = 83/212 (39%), Gaps = 14/212 (6%)
Query: 221 KSRSPSTESQLMSKGDEDTKDDSEETVPNPFSQL----TDQELEEYKKEVERKKLELDGE 276
K +P+T + + + ET P S++ T +E K + EL E
Sbjct: 731 KETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAE 790
Query: 277 K-----ETAPEEPGSPAKSAPASP---VQSPAKEAETKSPLVSPSKSLEEGTKKTETSKA 328
E +P+EPG P PA+ + + AK+ T+ L + ++ K T+ +
Sbjct: 791 PTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRTTPETTTAAPKMTK--ET 848
Query: 329 ATTEPETTQPEGVVVNGREEEQTAEEILSKGLSQMTTSADTDVDTSKDKTESVTSGPMSP 388
ATT +TT+ + + T ++ ++ + T+ T+ KT + T P
Sbjct: 849 ATTTEKTTESKITATTTQVTSTTTQDTTPFKITTLKTTTLAPKVTTTKKTITTTEIMNKP 908
Query: 389 EGSPSKSPSKKKKKFRTPSFLKKSKKKEKVES 420
E + K TP K +K +K S
Sbjct: 909 EETAKPKDRATNSKATTPKPQKPTKAPKKPTS 940
Score = 41.6 bits (96), Expect = 0.001
Identities = 35/133 (26%), Positives = 52/133 (39%), Gaps = 8/133 (6%)
Query: 277 KETAPEEPGSPAKSAPASPVQSPAKEAETKSPLVSPSKSLEEGTKKTETS----KAATTE 332
KE AP P PA + P + KE +P K L T K TS K A T
Sbjct: 670 KEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTT 729
Query: 333 PETTQP----EGVVVNGREEEQTAEEILSKGLSQMTTSADTDVDTSKDKTESVTSGPMSP 388
P+ T P E ++ T E S+++T T T+ K+ ++ +S
Sbjct: 730 PKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSA 789
Query: 389 EGSPSKSPSKKKK 401
E +P + K+
Sbjct: 790 EPTPKALENSPKE 802
Score = 41.2 bits (95), Expect = 0.002
Identities = 39/149 (26%), Positives = 53/149 (35%), Gaps = 16/149 (10%)
Query: 263 KKEVERKKLELDGEKETAPEEPGSPAKSAPASPVQSPAKEAETKSPLVSPSKSLEEGTKK 322
K E K L KE P P PA + P P + K A T +P+ + T
Sbjct: 241 KAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTP 300
Query: 323 TETSKAATTEPETTQPEGVVVNGREEEQTAEEILSKGLSQMTTSADTDVDTSKDKTESVT 382
E + T EP T P ++ A + T SA T T K E
Sbjct: 301 KEPAPTTTKEPAPTTP----------KEPAPTTTKEPAPTTTKSAPT---TPK---EPAP 344
Query: 383 SGPMSPEGSPSKSPSKKKKKFRTPSFLKK 411
+ P P + K P+ K TP+ K+
Sbjct: 345 TTPKKPAPTTPKEPAPTTPKEPTPTTPKE 373
Score = 39.3 bits (90), Expect = 0.007
Identities = 60/273 (21%), Positives = 98/273 (35%), Gaps = 25/273 (9%)
Query: 158 TLRVSKEQDHFLISPKGVSCSEVTASSLIKEVLEMRNKIREQNRQDVKSAGPQSQLLASV 217
+L V+KE + K + + S+ KE + + + K P S++LA
Sbjct: 182 SLTVNKETT---VETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAK- 237
Query: 218 IAEKSRSPSTESQLMSKGDE-DTKDDSEETVPNPFSQLTDQELEE--YKKEVERKKLELD 274
P+ +++ +KG T + T P + T +E K K
Sbjct: 238 -------PTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAP 290
Query: 275 GEKETAPEEPGSPAKSAPASPVQSPAKE---AETKSPLVSPSKSLEEGTKK---TETSKA 328
++AP P PA + P + KE TK P + +KS K+ T K
Sbjct: 291 TTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKP 350
Query: 329 ATTEPE----TTQPEGVVVNGREEEQTAEEILSKGLSQMTTSADTDVDTSKDKTESVTSG 384
A T P+ TT E +E T +E + +A + K + T+
Sbjct: 351 APTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTT- 409
Query: 385 PMSPEGSPSKSPSKKKKKFRTPSFLKKSKKKEK 417
P P + +K PS K P+ K + K
Sbjct: 410 PKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTK 442
Score = 39.3 bits (90), Expect = 0.007
Identities = 36/137 (26%), Positives = 50/137 (36%), Gaps = 11/137 (8%)
Query: 277 KETAPEEPGSPAKSAPASPVQSPAKEAETKSPLVSPSKSLEEGTKKTETSKAATT--EPE 334
KE AP P PA +AP P + KE +P + +E + T A TT
Sbjct: 379 KEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAP 438
Query: 335 TTQPEGVVVNGREEEQTAEEILSKGLSQMTTSADTDVDTSKDKTESVTSGPMSPEGSPSK 394
TT E + T +E TT+ + T K E + P P + K
Sbjct: 439 TTTKEPAPTTTKSAPTTPKE------PSPTTTKEPAPTTPK---EPAPTTPKKPAPTTPK 489
Query: 395 SPSKKKKKFRTPSFLKK 411
P+ K P+ KK
Sbjct: 490 EPAPTTPKEPAPTTTKK 506
Score = 39.3 bits (90), Expect = 0.007
Identities = 45/211 (21%), Positives = 71/211 (33%), Gaps = 24/211 (11%)
Query: 205 KSAGPQSQLLASVIAEKSRSPSTESQLMSKGDED----TKDDSEETVPNPFSQLTDQELE 260
K P + + K +P+T +L E T + T P + T +E
Sbjct: 505 KKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPT 564
Query: 261 EYKKEVERKKLELDGEKETAPEEPGSPAKSAPASPVQSPAKEAETKSPLVSPSKSLEEGT 320
E K AP P PA + P P + KE +P + + +GT
Sbjct: 565 PTTPEEPAPTTP----KAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTP-KETAPTTPKGT 619
Query: 321 KKTETSKAATTEPETTQPEGVVVNGREEEQTAEEILSKGLSQMTTSADTDVDTSKDKTES 380
T + A T P+ P+ + +E +T+ D T+ T
Sbjct: 620 APTTLKEPAPTTPKKPAPKELAPTTTKE-------------PTSTTCDKPAPTTPKGTAP 666
Query: 381 VTSGPMSPEGSPSKSPSKKKKKFRTPSFLKK 411
T P P + K P+ K P+ LK+
Sbjct: 667 TT--PKEPAPTTPKEPAPTTPKGTAPTTLKE 695
Score = 37.0 bits (84), Expect = 0.034
Identities = 51/231 (22%), Positives = 88/231 (38%), Gaps = 22/231 (9%)
Query: 171 SPK--GVSCSEVTASSLIKEVLEMRNKIREQNRQ---DVKSAGPQSQLLASVIAEKSRSP 225
SPK GV ++ A++ + ++K E++ + + +A P+ + EK+
Sbjct: 799 SPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEKT--- 855
Query: 226 STESQLMSKGDEDTKDDSEETVPNPFSQLTDQELEEYKKEVERKKLELDGEKETAPEEPG 285
TES++ + + T +++T P + L L K KK E PEE
Sbjct: 856 -TESKITATTTQVTSTTTQDTTPFKITTLKTTTLAP--KVTTTKKTITTTEIMNKPEETA 912
Query: 286 SPAKSAPASPVQSPAKEAETKSPLVSPSKSLEEGTKKTETSKAATTEPETTQPEGVVVNG 345
P A S +P + TK+P S TKK +T T P +
Sbjct: 913 KPKDRATNSKATTPKPQKPTKAPKKPTS------TKKPKTMPRVRKPKTTPTPRKMTSTM 966
Query: 346 REEEQTAEEILSKGLSQMTTSADTDVDTSKDKTESVTSGPMSPEGSPSKSP 396
E T+ +++ + Q TT + T K V G+ ++P
Sbjct: 967 PELNPTSR--IAEAMLQTTTRPN---QTPNSKLVEVNPKSEDAGGAEGETP 1012
Score = 36.6 bits (83), Expect = 0.044
Identities = 34/148 (22%), Positives = 56/148 (37%), Gaps = 7/148 (4%)
Query: 277 KETAPEEPGSPAKSAPASPVQSPAKEAETKSPLVSPSKSLEEGTKKTETSKAATTEPETT 336
K T P+ + SP + AK + L S + +E + T+ TT
Sbjct: 139 KVTTPDTSTTQHNKVSTSPKITTAKPINPRPSLPPNSDTSKETSLTVNKETTVETKETTT 198
Query: 337 QPEGVVVNGREEEQTAEEILSKGLSQMTTSADTDVDTSK--DKTESVTSG-----PMSPE 389
+ +G+E+ +A+E S + A T +K K E+ T G P P
Sbjct: 199 TNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPT 258
Query: 390 GSPSKSPSKKKKKFRTPSFLKKSKKKEK 417
+ K P+ K TP+ +K + K
Sbjct: 259 PTTPKEPASTTPKEPTPTTIKSAPTTPK 286
Score = 36.6 bits (83), Expect = 0.044
Identities = 38/144 (26%), Positives = 51/144 (35%), Gaps = 9/144 (6%)
Query: 277 KETAPEEPGSPAKSAPASPVQSPAKEAETKSPLVSPSKSLEEGTKKTETSKAATTEPETT 336
K TAP PA + P P TK P + S T K ET+ EP T
Sbjct: 686 KGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPK-ETAPTTPKEPAPT 744
Query: 337 QPEGVVVNGREEEQTAEEILSKGLSQMTTSADTDVDTSKDKTESVTSGPMSP---EGSPS 393
P+ E T S+ + TT T + S D++ S +P E SP
Sbjct: 745 TPKKPAPTTPE---TPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPK 801
Query: 394 KS--PSKKKKKFRTPSFLKKSKKK 415
+ P+ K P +K K
Sbjct: 802 EPGVPTTKTPAATKPEMTTTAKDK 825
Score = 30.0 bits (66), Expect = 4.1
Identities = 28/138 (20%), Positives = 48/138 (34%), Gaps = 10/138 (7%)
Query: 279 TAPEEPG-----SPAKSAPASPVQSPAKEAETKSPLVSPSKSLEEGTKKTETSKAATTEP 333
T P+EP PA + P P + K+ +P P+ + + T T K A T P
Sbjct: 454 TTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTP-KEPAPTTPKEPAPTTTKKPAPTTP 512
Query: 334 ETTQPEGVVVNGREEEQTAEEILSKGLSQMTTSADTDVDTSKDKTESVTSGPMSPEGSPS 393
+ P +E T + L+ + + E + P P +
Sbjct: 513 KEPAP----TTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTP 568
Query: 394 KSPSKKKKKFRTPSFLKK 411
+ P+ K P+ K+
Sbjct: 569 EEPAPTTPKAAAPNTPKE 586
Score = 30.0 bits (66), Expect = 4.1
Identities = 28/139 (20%), Positives = 48/139 (34%), Gaps = 10/139 (7%)
Query: 279 TAPEEPG-----SPAKSAPASPVQSPAKEAETKSPLVSPSKSLEEGTKKTETSKAATTEP 333
T P++P PA + P P + K+ +P P+ + + T T K T P
Sbjct: 478 TTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTP-KEPAPTTPKETAPTTPKKLTPTTP 536
Query: 334 ETTQPEGVVVNGREEEQTAEEILSKGLSQMTTSADTDVDTSKDKTESVTSGPMSPEGSPS 393
E P + T E L+ + T + + + P P +
Sbjct: 537 EKLAP----TTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTP 592
Query: 394 KSPSKKKKKFRTPSFLKKS 412
K P+ K P+ K++
Sbjct: 593 KEPAPTTPKEPAPTTPKET 611
>gi|189181720 proteoglycan 4 isoform B [Homo sapiens]
Length = 1363
Score = 44.7 bits (104), Expect = 2e-04
Identities = 47/212 (22%), Positives = 83/212 (39%), Gaps = 14/212 (6%)
Query: 221 KSRSPSTESQLMSKGDEDTKDDSEETVPNPFSQL----TDQELEEYKKEVERKKLELDGE 276
K +P+T + + + ET P S++ T +E K + EL E
Sbjct: 783 KETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAE 842
Query: 277 K-----ETAPEEPGSPAKSAPASP---VQSPAKEAETKSPLVSPSKSLEEGTKKTETSKA 328
E +P+EPG P PA+ + + AK+ T+ L + ++ K T+ +
Sbjct: 843 PTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRTTPETTTAAPKMTK--ET 900
Query: 329 ATTEPETTQPEGVVVNGREEEQTAEEILSKGLSQMTTSADTDVDTSKDKTESVTSGPMSP 388
ATT +TT+ + + T ++ ++ + T+ T+ KT + T P
Sbjct: 901 ATTTEKTTESKITATTTQVTSTTTQDTTPFKITTLKTTTLAPKVTTTKKTITTTEIMNKP 960
Query: 389 EGSPSKSPSKKKKKFRTPSFLKKSKKKEKVES 420
E + K TP K +K +K S
Sbjct: 961 EETAKPKDRATNSKATTPKPQKPTKAPKKPTS 992
Score = 42.7 bits (99), Expect = 6e-04
Identities = 49/238 (20%), Positives = 87/238 (36%), Gaps = 17/238 (7%)
Query: 187 KEVLEMRNKIREQNRQDVKSAGPQSQLLASVIAEKSRSPSTESQLMSKGDEDTKDDSEET 246
+E+ E + Q S+ S + + + K+ + + E Q K +D K + +
Sbjct: 111 EEITEEHSVSENQESSSSSSSSSSSSTIRKIKSSKNSAANRELQKKLKV-KDNKKNRTKK 169
Query: 247 VPNPFSQLTDQELEEYKKEVERKKLELDGEKETAPEEPGSPAKSAPASPVQSPAKEAETK 306
P P + D+ L+ K T P+ + SP + AK +
Sbjct: 170 KPTPKPPVVDEA---------GSGLDNGDFKVTTPDTSTTQHNKVSTSPKITTAKPINPR 220
Query: 307 SPLVSPSKSLEEGTKKTETSKAATTEPETTQPEGVVVNGREEEQTAEEILSKGLSQMTTS 366
L S + +E + T+ TT + +G+E+ +A+E S +
Sbjct: 221 PSLPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDL 280
Query: 367 ADTDVDTSK--DKTESVTSG-----PMSPEGSPSKSPSKKKKKFRTPSFLKKSKKKEK 417
A T +K K E+ T G P P + K P+ K TP+ +K + K
Sbjct: 281 APTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPK 338
Score = 41.6 bits (96), Expect = 0.001
Identities = 35/133 (26%), Positives = 52/133 (39%), Gaps = 8/133 (6%)
Query: 277 KETAPEEPGSPAKSAPASPVQSPAKEAETKSPLVSPSKSLEEGTKKTETS----KAATTE 332
KE AP P PA + P + KE +P K L T K TS K A T
Sbjct: 722 KEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTT 781
Query: 333 PETTQP----EGVVVNGREEEQTAEEILSKGLSQMTTSADTDVDTSKDKTESVTSGPMSP 388
P+ T P E ++ T E S+++T T T+ K+ ++ +S
Sbjct: 782 PKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSA 841
Query: 389 EGSPSKSPSKKKK 401
E +P + K+
Sbjct: 842 EPTPKALENSPKE 854
Score = 41.2 bits (95), Expect = 0.002
Identities = 39/149 (26%), Positives = 53/149 (35%), Gaps = 16/149 (10%)
Query: 263 KKEVERKKLELDGEKETAPEEPGSPAKSAPASPVQSPAKEAETKSPLVSPSKSLEEGTKK 322
K E K L KE P P PA + P P + K A T +P+ + T
Sbjct: 293 KAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTP 352
Query: 323 TETSKAATTEPETTQPEGVVVNGREEEQTAEEILSKGLSQMTTSADTDVDTSKDKTESVT 382
E + T EP T P ++ A + T SA T T K E
Sbjct: 353 KEPAPTTTKEPAPTTP----------KEPAPTTTKEPAPTTTKSAPT---TPK---EPAP 396
Query: 383 SGPMSPEGSPSKSPSKKKKKFRTPSFLKK 411
+ P P + K P+ K TP+ K+
Sbjct: 397 TTPKKPAPTTPKEPAPTTPKEPTPTTPKE 425
Score = 39.3 bits (90), Expect = 0.007
Identities = 60/273 (21%), Positives = 98/273 (35%), Gaps = 25/273 (9%)
Query: 158 TLRVSKEQDHFLISPKGVSCSEVTASSLIKEVLEMRNKIREQNRQDVKSAGPQSQLLASV 217
+L V+KE + K + + S+ KE + + + K P S++LA
Sbjct: 234 SLTVNKETT---VETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAK- 289
Query: 218 IAEKSRSPSTESQLMSKGDE-DTKDDSEETVPNPFSQLTDQELEE--YKKEVERKKLELD 274
P+ +++ +KG T + T P + T +E K K
Sbjct: 290 -------PTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAP 342
Query: 275 GEKETAPEEPGSPAKSAPASPVQSPAKE---AETKSPLVSPSKSLEEGTKK---TETSKA 328
++AP P PA + P + KE TK P + +KS K+ T K
Sbjct: 343 TTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKP 402
Query: 329 ATTEPE----TTQPEGVVVNGREEEQTAEEILSKGLSQMTTSADTDVDTSKDKTESVTSG 384
A T P+ TT E +E T +E + +A + K + T+
Sbjct: 403 APTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTT- 461
Query: 385 PMSPEGSPSKSPSKKKKKFRTPSFLKKSKKKEK 417
P P + +K PS K P+ K + K
Sbjct: 462 PKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTK 494
Score = 39.3 bits (90), Expect = 0.007
Identities = 36/137 (26%), Positives = 50/137 (36%), Gaps = 11/137 (8%)
Query: 277 KETAPEEPGSPAKSAPASPVQSPAKEAETKSPLVSPSKSLEEGTKKTETSKAATT--EPE 334
KE AP P PA +AP P + KE +P + +E + T A TT
Sbjct: 431 KEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAP 490
Query: 335 TTQPEGVVVNGREEEQTAEEILSKGLSQMTTSADTDVDTSKDKTESVTSGPMSPEGSPSK 394
TT E + T +E TT+ + T K E + P P + K
Sbjct: 491 TTTKEPAPTTTKSAPTTPKE------PSPTTTKEPAPTTPK---EPAPTTPKKPAPTTPK 541
Query: 395 SPSKKKKKFRTPSFLKK 411
P+ K P+ KK
Sbjct: 542 EPAPTTPKEPAPTTTKK 558
Score = 39.3 bits (90), Expect = 0.007
Identities = 45/211 (21%), Positives = 71/211 (33%), Gaps = 24/211 (11%)
Query: 205 KSAGPQSQLLASVIAEKSRSPSTESQLMSKGDED----TKDDSEETVPNPFSQLTDQELE 260
K P + + K +P+T +L E T + T P + T +E
Sbjct: 557 KKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPT 616
Query: 261 EYKKEVERKKLELDGEKETAPEEPGSPAKSAPASPVQSPAKEAETKSPLVSPSKSLEEGT 320
E K AP P PA + P P + KE +P + + +GT
Sbjct: 617 PTTPEEPAPTTP----KAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTP-KETAPTTPKGT 671
Query: 321 KKTETSKAATTEPETTQPEGVVVNGREEEQTAEEILSKGLSQMTTSADTDVDTSKDKTES 380
T + A T P+ P+ + +E +T+ D T+ T
Sbjct: 672 APTTLKEPAPTTPKKPAPKELAPTTTKE-------------PTSTTCDKPAPTTPKGTAP 718
Query: 381 VTSGPMSPEGSPSKSPSKKKKKFRTPSFLKK 411
T P P + K P+ K P+ LK+
Sbjct: 719 TT--PKEPAPTTPKEPAPTTPKGTAPTTLKE 747
Score = 37.0 bits (84), Expect = 0.034
Identities = 51/231 (22%), Positives = 88/231 (38%), Gaps = 22/231 (9%)
Query: 171 SPK--GVSCSEVTASSLIKEVLEMRNKIREQNRQ---DVKSAGPQSQLLASVIAEKSRSP 225
SPK GV ++ A++ + ++K E++ + + +A P+ + EK+
Sbjct: 851 SPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEKT--- 907
Query: 226 STESQLMSKGDEDTKDDSEETVPNPFSQLTDQELEEYKKEVERKKLELDGEKETAPEEPG 285
TES++ + + T +++T P + L L K KK E PEE
Sbjct: 908 -TESKITATTTQVTSTTTQDTTPFKITTLKTTTLAP--KVTTTKKTITTTEIMNKPEETA 964
Query: 286 SPAKSAPASPVQSPAKEAETKSPLVSPSKSLEEGTKKTETSKAATTEPETTQPEGVVVNG 345
P A S +P + TK+P S TKK +T T P +
Sbjct: 965 KPKDRATNSKATTPKPQKPTKAPKKPTS------TKKPKTMPRVRKPKTTPTPRKMTSTM 1018
Query: 346 REEEQTAEEILSKGLSQMTTSADTDVDTSKDKTESVTSGPMSPEGSPSKSP 396
E T+ +++ + Q TT + T K V G+ ++P
Sbjct: 1019 PELNPTSR--IAEAMLQTTTRPN---QTPNSKLVEVNPKSEDAGGAEGETP 1064
Score = 36.6 bits (83), Expect = 0.044
Identities = 38/144 (26%), Positives = 51/144 (35%), Gaps = 9/144 (6%)
Query: 277 KETAPEEPGSPAKSAPASPVQSPAKEAETKSPLVSPSKSLEEGTKKTETSKAATTEPETT 336
K TAP PA + P P TK P + S T K ET+ EP T
Sbjct: 738 KGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPK-ETAPTTPKEPAPT 796
Query: 337 QPEGVVVNGREEEQTAEEILSKGLSQMTTSADTDVDTSKDKTESVTSGPMSP---EGSPS 393
P+ E T S+ + TT T + S D++ S +P E SP
Sbjct: 797 TPKKPAPTTPE---TPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPK 853
Query: 394 KS--PSKKKKKFRTPSFLKKSKKK 415
+ P+ K P +K K
Sbjct: 854 EPGVPTTKTPAATKPEMTTTAKDK 877
Score = 30.0 bits (66), Expect = 4.1
Identities = 28/138 (20%), Positives = 48/138 (34%), Gaps = 10/138 (7%)
Query: 279 TAPEEPG-----SPAKSAPASPVQSPAKEAETKSPLVSPSKSLEEGTKKTETSKAATTEP 333
T P+EP PA + P P + K+ +P P+ + + T T K A T P
Sbjct: 506 TTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTP-KEPAPTTPKEPAPTTTKKPAPTTP 564
Query: 334 ETTQPEGVVVNGREEEQTAEEILSKGLSQMTTSADTDVDTSKDKTESVTSGPMSPEGSPS 393
+ P +E T + L+ + + E + P P +
Sbjct: 565 KEPAP----TTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTP 620
Query: 394 KSPSKKKKKFRTPSFLKK 411
+ P+ K P+ K+
Sbjct: 621 EEPAPTTPKAAAPNTPKE 638
Score = 30.0 bits (66), Expect = 4.1
Identities = 28/139 (20%), Positives = 48/139 (34%), Gaps = 10/139 (7%)
Query: 279 TAPEEPG-----SPAKSAPASPVQSPAKEAETKSPLVSPSKSLEEGTKKTETSKAATTEP 333
T P++P PA + P P + K+ +P P+ + + T T K T P
Sbjct: 530 TTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTP-KEPAPTTPKETAPTTPKKLTPTTP 588
Query: 334 ETTQPEGVVVNGREEEQTAEEILSKGLSQMTTSADTDVDTSKDKTESVTSGPMSPEGSPS 393
E P + T E L+ + T + + + P P +
Sbjct: 589 EKLAP----TTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTP 644
Query: 394 KSPSKKKKKFRTPSFLKKS 412
K P+ K P+ K++
Sbjct: 645 KEPAPTTPKEPAPTTPKET 663
>gi|67190163 proteoglycan 4 isoform A [Homo sapiens]
Length = 1404
Score = 44.7 bits (104), Expect = 2e-04
Identities = 47/212 (22%), Positives = 83/212 (39%), Gaps = 14/212 (6%)
Query: 221 KSRSPSTESQLMSKGDEDTKDDSEETVPNPFSQL----TDQELEEYKKEVERKKLELDGE 276
K +P+T + + + ET P S++ T +E K + EL E
Sbjct: 824 KETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAE 883
Query: 277 K-----ETAPEEPGSPAKSAPASP---VQSPAKEAETKSPLVSPSKSLEEGTKKTETSKA 328
E +P+EPG P PA+ + + AK+ T+ L + ++ K T+ +
Sbjct: 884 PTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRTTPETTTAAPKMTK--ET 941
Query: 329 ATTEPETTQPEGVVVNGREEEQTAEEILSKGLSQMTTSADTDVDTSKDKTESVTSGPMSP 388
ATT +TT+ + + T ++ ++ + T+ T+ KT + T P
Sbjct: 942 ATTTEKTTESKITATTTQVTSTTTQDTTPFKITTLKTTTLAPKVTTTKKTITTTEIMNKP 1001
Query: 389 EGSPSKSPSKKKKKFRTPSFLKKSKKKEKVES 420
E + K TP K +K +K S
Sbjct: 1002 EETAKPKDRATNSKATTPKPQKPTKAPKKPTS 1033
Score = 42.7 bits (99), Expect = 6e-04
Identities = 49/238 (20%), Positives = 87/238 (36%), Gaps = 17/238 (7%)
Query: 187 KEVLEMRNKIREQNRQDVKSAGPQSQLLASVIAEKSRSPSTESQLMSKGDEDTKDDSEET 246
+E+ E + Q S+ S + + + K+ + + E Q K +D K + +
Sbjct: 152 EEITEEHSVSENQESSSSSSSSSSSSTIRKIKSSKNSAANRELQKKLKV-KDNKKNRTKK 210
Query: 247 VPNPFSQLTDQELEEYKKEVERKKLELDGEKETAPEEPGSPAKSAPASPVQSPAKEAETK 306
P P + D+ L+ K T P+ + SP + AK +
Sbjct: 211 KPTPKPPVVDEA---------GSGLDNGDFKVTTPDTSTTQHNKVSTSPKITTAKPINPR 261
Query: 307 SPLVSPSKSLEEGTKKTETSKAATTEPETTQPEGVVVNGREEEQTAEEILSKGLSQMTTS 366
L S + +E + T+ TT + +G+E+ +A+E S +
Sbjct: 262 PSLPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDL 321
Query: 367 ADTDVDTSK--DKTESVTSG-----PMSPEGSPSKSPSKKKKKFRTPSFLKKSKKKEK 417
A T +K K E+ T G P P + K P+ K TP+ +K + K
Sbjct: 322 APTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPK 379
Score = 41.6 bits (96), Expect = 0.001
Identities = 35/133 (26%), Positives = 52/133 (39%), Gaps = 8/133 (6%)
Query: 277 KETAPEEPGSPAKSAPASPVQSPAKEAETKSPLVSPSKSLEEGTKKTETS----KAATTE 332
KE AP P PA + P + KE +P K L T K TS K A T
Sbjct: 763 KEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTT 822
Query: 333 PETTQP----EGVVVNGREEEQTAEEILSKGLSQMTTSADTDVDTSKDKTESVTSGPMSP 388
P+ T P E ++ T E S+++T T T+ K+ ++ +S
Sbjct: 823 PKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSA 882
Query: 389 EGSPSKSPSKKKK 401
E +P + K+
Sbjct: 883 EPTPKALENSPKE 895
Score = 41.2 bits (95), Expect = 0.002
Identities = 39/149 (26%), Positives = 53/149 (35%), Gaps = 16/149 (10%)
Query: 263 KKEVERKKLELDGEKETAPEEPGSPAKSAPASPVQSPAKEAETKSPLVSPSKSLEEGTKK 322
K E K L KE P P PA + P P + K A T +P+ + T
Sbjct: 334 KAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTP 393
Query: 323 TETSKAATTEPETTQPEGVVVNGREEEQTAEEILSKGLSQMTTSADTDVDTSKDKTESVT 382
E + T EP T P ++ A + T SA T T K E
Sbjct: 394 KEPAPTTTKEPAPTTP----------KEPAPTTTKEPAPTTTKSAPT---TPK---EPAP 437
Query: 383 SGPMSPEGSPSKSPSKKKKKFRTPSFLKK 411
+ P P + K P+ K TP+ K+
Sbjct: 438 TTPKKPAPTTPKEPAPTTPKEPTPTTPKE 466
Score = 39.3 bits (90), Expect = 0.007
Identities = 60/273 (21%), Positives = 98/273 (35%), Gaps = 25/273 (9%)
Query: 158 TLRVSKEQDHFLISPKGVSCSEVTASSLIKEVLEMRNKIREQNRQDVKSAGPQSQLLASV 217
+L V+KE + K + + S+ KE + + + K P S++LA
Sbjct: 275 SLTVNKETT---VETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAK- 330
Query: 218 IAEKSRSPSTESQLMSKGDE-DTKDDSEETVPNPFSQLTDQELEE--YKKEVERKKLELD 274
P+ +++ +KG T + T P + T +E K K
Sbjct: 331 -------PTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAP 383
Query: 275 GEKETAPEEPGSPAKSAPASPVQSPAKE---AETKSPLVSPSKSLEEGTKK---TETSKA 328
++AP P PA + P + KE TK P + +KS K+ T K
Sbjct: 384 TTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKP 443
Query: 329 ATTEPE----TTQPEGVVVNGREEEQTAEEILSKGLSQMTTSADTDVDTSKDKTESVTSG 384
A T P+ TT E +E T +E + +A + K + T+
Sbjct: 444 APTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTT- 502
Query: 385 PMSPEGSPSKSPSKKKKKFRTPSFLKKSKKKEK 417
P P + +K PS K P+ K + K
Sbjct: 503 PKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTK 535
Score = 39.3 bits (90), Expect = 0.007
Identities = 36/137 (26%), Positives = 50/137 (36%), Gaps = 11/137 (8%)
Query: 277 KETAPEEPGSPAKSAPASPVQSPAKEAETKSPLVSPSKSLEEGTKKTETSKAATT--EPE 334
KE AP P PA +AP P + KE +P + +E + T A TT
Sbjct: 472 KEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAP 531
Query: 335 TTQPEGVVVNGREEEQTAEEILSKGLSQMTTSADTDVDTSKDKTESVTSGPMSPEGSPSK 394
TT E + T +E TT+ + T K E + P P + K
Sbjct: 532 TTTKEPAPTTTKSAPTTPKE------PSPTTTKEPAPTTPK---EPAPTTPKKPAPTTPK 582
Query: 395 SPSKKKKKFRTPSFLKK 411
P+ K P+ KK
Sbjct: 583 EPAPTTPKEPAPTTTKK 599
Score = 39.3 bits (90), Expect = 0.007
Identities = 45/211 (21%), Positives = 71/211 (33%), Gaps = 24/211 (11%)
Query: 205 KSAGPQSQLLASVIAEKSRSPSTESQLMSKGDED----TKDDSEETVPNPFSQLTDQELE 260
K P + + K +P+T +L E T + T P + T +E
Sbjct: 598 KKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPT 657
Query: 261 EYKKEVERKKLELDGEKETAPEEPGSPAKSAPASPVQSPAKEAETKSPLVSPSKSLEEGT 320
E K AP P PA + P P + KE +P + + +GT
Sbjct: 658 PTTPEEPAPTTP----KAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTP-KETAPTTPKGT 712
Query: 321 KKTETSKAATTEPETTQPEGVVVNGREEEQTAEEILSKGLSQMTTSADTDVDTSKDKTES 380
T + A T P+ P+ + +E +T+ D T+ T
Sbjct: 713 APTTLKEPAPTTPKKPAPKELAPTTTKE-------------PTSTTCDKPAPTTPKGTAP 759
Query: 381 VTSGPMSPEGSPSKSPSKKKKKFRTPSFLKK 411
T P P + K P+ K P+ LK+
Sbjct: 760 TT--PKEPAPTTPKEPAPTTPKGTAPTTLKE 788
Score = 37.0 bits (84), Expect = 0.034
Identities = 51/231 (22%), Positives = 88/231 (38%), Gaps = 22/231 (9%)
Query: 171 SPK--GVSCSEVTASSLIKEVLEMRNKIREQNRQ---DVKSAGPQSQLLASVIAEKSRSP 225
SPK GV ++ A++ + ++K E++ + + +A P+ + EK+
Sbjct: 892 SPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEKT--- 948
Query: 226 STESQLMSKGDEDTKDDSEETVPNPFSQLTDQELEEYKKEVERKKLELDGEKETAPEEPG 285
TES++ + + T +++T P + L L K KK E PEE
Sbjct: 949 -TESKITATTTQVTSTTTQDTTPFKITTLKTTTLAP--KVTTTKKTITTTEIMNKPEETA 1005
Query: 286 SPAKSAPASPVQSPAKEAETKSPLVSPSKSLEEGTKKTETSKAATTEPETTQPEGVVVNG 345
P A S +P + TK+P S TKK +T T P +
Sbjct: 1006 KPKDRATNSKATTPKPQKPTKAPKKPTS------TKKPKTMPRVRKPKTTPTPRKMTSTM 1059
Query: 346 REEEQTAEEILSKGLSQMTTSADTDVDTSKDKTESVTSGPMSPEGSPSKSP 396
E T+ +++ + Q TT + T K V G+ ++P
Sbjct: 1060 PELNPTSR--IAEAMLQTTTRPN---QTPNSKLVEVNPKSEDAGGAEGETP 1105
Score = 36.6 bits (83), Expect = 0.044
Identities = 38/144 (26%), Positives = 51/144 (35%), Gaps = 9/144 (6%)
Query: 277 KETAPEEPGSPAKSAPASPVQSPAKEAETKSPLVSPSKSLEEGTKKTETSKAATTEPETT 336
K TAP PA + P P TK P + S T K ET+ EP T
Sbjct: 779 KGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPK-ETAPTTPKEPAPT 837
Query: 337 QPEGVVVNGREEEQTAEEILSKGLSQMTTSADTDVDTSKDKTESVTSGPMSP---EGSPS 393
P+ E T S+ + TT T + S D++ S +P E SP
Sbjct: 838 TPKKPAPTTPE---TPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPK 894
Query: 394 KS--PSKKKKKFRTPSFLKKSKKK 415
+ P+ K P +K K
Sbjct: 895 EPGVPTTKTPAATKPEMTTTAKDK 918
Score = 30.0 bits (66), Expect = 4.1
Identities = 28/138 (20%), Positives = 48/138 (34%), Gaps = 10/138 (7%)
Query: 279 TAPEEPG-----SPAKSAPASPVQSPAKEAETKSPLVSPSKSLEEGTKKTETSKAATTEP 333
T P+EP PA + P P + K+ +P P+ + + T T K A T P
Sbjct: 547 TTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTP-KEPAPTTPKEPAPTTTKKPAPTTP 605
Query: 334 ETTQPEGVVVNGREEEQTAEEILSKGLSQMTTSADTDVDTSKDKTESVTSGPMSPEGSPS 393
+ P +E T + L+ + + E + P P +
Sbjct: 606 KEPAP----TTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTP 661
Query: 394 KSPSKKKKKFRTPSFLKK 411
+ P+ K P+ K+
Sbjct: 662 EEPAPTTPKAAAPNTPKE 679
Score = 30.0 bits (66), Expect = 4.1
Identities = 28/139 (20%), Positives = 48/139 (34%), Gaps = 10/139 (7%)
Query: 279 TAPEEPG-----SPAKSAPASPVQSPAKEAETKSPLVSPSKSLEEGTKKTETSKAATTEP 333
T P++P PA + P P + K+ +P P+ + + T T K T P
Sbjct: 571 TTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTP-KEPAPTTPKETAPTTPKKLTPTTP 629
Query: 334 ETTQPEGVVVNGREEEQTAEEILSKGLSQMTTSADTDVDTSKDKTESVTSGPMSPEGSPS 393
E P + T E L+ + T + + + P P +
Sbjct: 630 EKLAP----TTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTP 685
Query: 394 KSPSKKKKKFRTPSFLKKS 412
K P+ K P+ K++
Sbjct: 686 KEPAPTTPKEPAPTTPKET 704
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.304 0.121 0.322
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 17,378,191
Number of Sequences: 37866
Number of extensions: 873229
Number of successful extensions: 8902
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 168
Number of HSP's successfully gapped in prelim test: 889
Number of HSP's that attempted gapping in prelim test: 6252
Number of HSP's gapped (non-prelim): 2762
length of query: 420
length of database: 18,247,518
effective HSP length: 105
effective length of query: 315
effective length of database: 14,271,588
effective search space: 4495550220
effective search space used: 4495550220
T: 11
A: 40
X1: 16 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 43 (21.9 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.