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Search of human proteins with 90669931
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|90669931 tetratricopeptide repeat domain 12 [Homo sapiens]
(705 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|90669931 tetratricopeptide repeat domain 12 [Homo sapiens] 1368 0.0
gi|225735593 RNA polymerase II associated protein 3 isoform 2 [H... 79 1e-14
gi|225735591 RNA polymerase II associated protein 3 isoform 1 [H... 79 1e-14
gi|5803181 stress-induced-phosphoprotein 1 (Hsp70/Hsp90-organizi... 79 1e-14
gi|4507711 tetratricopeptide repeat domain 1 [Homo sapiens] 78 2e-14
gi|21361356 translocase of outer mitochondrial membrane 34 [Homo... 78 3e-14
gi|24308141 small glutamine-rich tetratricopeptide repeat (TPR)-... 77 4e-14
gi|27262638 sperm associated antigen 1 [Homo sapiens] 72 2e-12
gi|27262636 sperm associated antigen 1 [Homo sapiens] 72 2e-12
gi|4506921 small glutamine-rich tetratricopeptide [Homo sapiens] 70 5e-12
gi|225735595 RNA polymerase II associated protein 3 isoform 3 [H... 68 3e-11
gi|56181387 STIP1 homology and U-box containing protein 1 [Homo ... 67 4e-11
gi|224809329 FK506 binding protein 5 isoform 1 [Homo sapiens] 66 1e-10
gi|224809327 FK506 binding protein 5 isoform 1 [Homo sapiens] 66 1e-10
gi|4758384 FK506 binding protein 5 isoform 1 [Homo sapiens] 66 1e-10
gi|5453958 protein phosphatase 5, catalytic subunit [Homo sapiens] 64 4e-10
gi|4503729 FK506 binding protein 52 [Homo sapiens] 64 5e-10
gi|221219056 DnaJ (Hsp40) homolog, subfamily C, member 7 isoform... 62 2e-09
gi|54607135 translocase of outer mitochondrial membrane 70 homol... 62 2e-09
gi|221219053 DnaJ (Hsp40) homolog, subfamily C, member 7 isoform... 61 4e-09
gi|224028289 tetratricopeptide repeat domain 28 [Homo sapiens] 59 1e-08
gi|73747840 LON peptidase N-terminal domain and ring finger 3 is... 56 1e-07
gi|156627581 tetratricopeptide repeat domain 4 [Homo sapiens] 54 5e-07
gi|75750484 cardiomyopathy associated 4 isoform 2 [Homo sapiens] 54 5e-07
gi|27477061 cardiomyopathy associated 4 isoform 1 [Homo sapiens] 54 5e-07
gi|75677570 dyslexia susceptibility 1 candidate 1 isoform a [Hom... 54 6e-07
gi|22095349 WD and tetratricopeptide repeats 1 [Homo sapiens] 53 8e-07
gi|37622896 LON peptidase N-terminal domain and ring finger 3 is... 52 1e-06
gi|89179321 smooth muscle cell associated protein-1 isoform 3 [H... 52 2e-06
gi|29725607 smooth muscle cell associated protein-1 isoform 2 [H... 52 2e-06
>gi|90669931 tetratricopeptide repeat domain 12 [Homo sapiens]
Length = 705
Score = 1368 bits (3542), Expect = 0.0
Identities = 705/705 (100%), Positives = 705/705 (100%)
Query: 1 MDADKEKDLQKFLKNVDEISNLIQEMNSDDPVVQQKAVLETEKRLLLMEEDQEEDECRTT 60
MDADKEKDLQKFLKNVDEISNLIQEMNSDDPVVQQKAVLETEKRLLLMEEDQEEDECRTT
Sbjct: 1 MDADKEKDLQKFLKNVDEISNLIQEMNSDDPVVQQKAVLETEKRLLLMEEDQEEDECRTT 60
Query: 61 LNKTMISPPQTAMKSAEEINSEAFLASVEKDAKERAKRRRENKVLADALKEKGNEAFAEG 120
LNKTMISPPQTAMKSAEEINSEAFLASVEKDAKERAKRRRENKVLADALKEKGNEAFAEG
Sbjct: 61 LNKTMISPPQTAMKSAEEINSEAFLASVEKDAKERAKRRRENKVLADALKEKGNEAFAEG 120
Query: 121 NYETAILRYSEGLEKLKDMKVLYTNRAQAYMKLEDYEKALVDCEWALKCDEKCTKAYFHM 180
NYETAILRYSEGLEKLKDMKVLYTNRAQAYMKLEDYEKALVDCEWALKCDEKCTKAYFHM
Sbjct: 121 NYETAILRYSEGLEKLKDMKVLYTNRAQAYMKLEDYEKALVDCEWALKCDEKCTKAYFHM 180
Query: 181 GKANLALKNYSVSRECYKKILEINPKLQTQVKGYLNQVDLQEKADLQEKEAHELLDSGKN 240
GKANLALKNYSVSRECYKKILEINPKLQTQVKGYLNQVDLQEKADLQEKEAHELLDSGKN
Sbjct: 181 GKANLALKNYSVSRECYKKILEINPKLQTQVKGYLNQVDLQEKADLQEKEAHELLDSGKN 240
Query: 241 TAVTTKNLLETLSKPDQIPLFYAGGIEILTEMINECTEQTLFRMHNGFSIISDNEVIRRC 300
TAVTTKNLLETLSKPDQIPLFYAGGIEILTEMINECTEQTLFRMHNGFSIISDNEVIRRC
Sbjct: 241 TAVTTKNLLETLSKPDQIPLFYAGGIEILTEMINECTEQTLFRMHNGFSIISDNEVIRRC 300
Query: 301 FSTAGNDAVEEMVCVSVLKLWQAVCSRNEENQRVLVIHHDRARLLAALLSSKVLAIRQQS 360
FSTAGNDAVEEMVCVSVLKLWQAVCSRNEENQRVLVIHHDRARLLAALLSSKVLAIRQQS
Sbjct: 301 FSTAGNDAVEEMVCVSVLKLWQAVCSRNEENQRVLVIHHDRARLLAALLSSKVLAIRQQS 360
Query: 361 FALLLHLAQTESGRSLIINHLDLTRLLEALVSFLDFSDKEANTAMGLFTDLALEERFQVW 420
FALLLHLAQTESGRSLIINHLDLTRLLEALVSFLDFSDKEANTAMGLFTDLALEERFQVW
Sbjct: 361 FALLLHLAQTESGRSLIINHLDLTRLLEALVSFLDFSDKEANTAMGLFTDLALEERFQVW 420
Query: 421 FQANLPGVLPALTGVLKTDPKVSSSSALCQCIAIMGNLSAEPTTRRHMAACEEFGDGCLS 480
FQANLPGVLPALTGVLKTDPKVSSSSALCQCIAIMGNLSAEPTTRRHMAACEEFGDGCLS
Sbjct: 421 FQANLPGVLPALTGVLKTDPKVSSSSALCQCIAIMGNLSAEPTTRRHMAACEEFGDGCLS 480
Query: 481 LLARCEEDVDLFREVIYTLLGLMMNLCLQAPFVSEVWAVEVSRRCLSLLNSQDGGILTRA 540
LLARCEEDVDLFREVIYTLLGLMMNLCLQAPFVSEVWAVEVSRRCLSLLNSQDGGILTRA
Sbjct: 481 LLARCEEDVDLFREVIYTLLGLMMNLCLQAPFVSEVWAVEVSRRCLSLLNSQDGGILTRA 540
Query: 541 AGVLSRTLSSSLKIVEEALRAGVVKKMMKFLKTGGETASRYAIKILAICTNSYHEAREEV 600
AGVLSRTLSSSLKIVEEALRAGVVKKMMKFLKTGGETASRYAIKILAICTNSYHEAREEV
Sbjct: 541 AGVLSRTLSSSLKIVEEALRAGVVKKMMKFLKTGGETASRYAIKILAICTNSYHEAREEV 600
Query: 601 IRLDKKLSVMMKLLSSEDEVLVGNAALCLGNCMEVPNVASSLLKTDLLQVLLKLAGSDTQ 660
IRLDKKLSVMMKLLSSEDEVLVGNAALCLGNCMEVPNVASSLLKTDLLQVLLKLAGSDTQ
Sbjct: 601 IRLDKKLSVMMKLLSSEDEVLVGNAALCLGNCMEVPNVASSLLKTDLLQVLLKLAGSDTQ 660
Query: 661 KTAVQVNAGIALGKLCTAEPRFAAQLRKLHGLEILNSTMKYISDS 705
KTAVQVNAGIALGKLCTAEPRFAAQLRKLHGLEILNSTMKYISDS
Sbjct: 661 KTAVQVNAGIALGKLCTAEPRFAAQLRKLHGLEILNSTMKYISDS 705
>gi|225735593 RNA polymerase II associated protein 3 isoform 2 [Homo
sapiens]
Length = 631
Score = 79.3 bits (194), Expect = 1e-14
Identities = 72/295 (24%), Positives = 143/295 (48%), Gaps = 34/295 (11%)
Query: 3 ADKEKDLQKFLK-NVDEISNLIQEMNSDDPVVQQKAVLETEKRLLLMEED---------- 51
A+K +LQ +K N +E+ + ++++ + + ++QK +E ++ + EE+
Sbjct: 4 ANKAIELQLQVKQNAEELQDFMRDLENWEKDIKQKD-MELRRQNGVPEENLPPIRNGNFR 62
Query: 52 -QEEDECRTTLNKTMISPPQTAMKSAE-----EINSEAFLASVEKDAKERAKRRRENKVL 105
+++ + + + KT + +KS + +++ + L ++KD +E++
Sbjct: 63 KKKKGKAKESSKKTREENTKNRIKSYDYEAWAKLDVDRILDELDKDDSTHESLSQESESE 122
Query: 106 ADA----------LKEKGNEAFAEGNYETAILRYSEGLEKLKDMKVLYTNRAQAYMKLED 155
D LKEKGN+ F +G Y+ AI Y++G++ VL TNRA AY +L+
Sbjct: 123 EDGIHVDSQKALVLKEKGNKYFKQGKYDEAIDCYTKGMDADPYNPVLPTNRASAYFRLKK 182
Query: 156 YEKALVDCEWALKCDEKCTKAYFHMGKANLALKNYSVSRECYKKILEINPKLQTQVKGYL 215
+ A DC A+ + TKAY G A AL+ +++ Y+++LE+ P + L
Sbjct: 183 FAVAESDCNLAVALNRSYTKAYSRRGAARFALQKLEEAKKDYERVLELEPN-NFEATNEL 241
Query: 216 NQVD--LQEKADLQEKEAHELLDS--GKNTAV-TTKNLLETLSKPDQIPLFYAGG 265
++ L K + KEA ++ S G+ + +N + +S+ D+ F+ G
Sbjct: 242 RKISQALASKENSYPKEADIVIKSTEGERKQIEAQQNKQQAISEKDRGNGFFKEG 296
Score = 70.1 bits (170), Expect = 7e-12
Identities = 47/175 (26%), Positives = 86/175 (49%), Gaps = 15/175 (8%)
Query: 82 EAFLASVEKDAKERAKRRRENKVLADALKEKGNEAFAEGNYETAILRYSEGLEKLKDMKV 141
EA + + + + ++NK A + K++GN F EG YE AI Y+ G+ +
Sbjct: 258 EADIVIKSTEGERKQIEAQQNKQQAISEKDRGNGFFKEGKYERAIECYTRGIAADGANAL 317
Query: 142 LYTNRAQAYMKLEDYEKALVDCEWALKCDEKCTKAYFHMGKANLALKNYSVSRECYKKIL 201
L NRA AY+K++ YE+A DC A+ D +KA+ G A L + +++ ++ +L
Sbjct: 318 LPANRAMAYLKIQKYEEAEKDCTQAILLDGSYSKAFARRGTARTFLGKLNEAKQDFETVL 377
Query: 202 EINPKLQTQVKGYLNQVDLQEKADLQEKEAHELLDSGKNTAVTTKNLLETLSKPD 256
+ P N+ + E + +++K +++ T NL++T+ PD
Sbjct: 378 LLEPG---------NKQAVTELSKIKKKPLKKVI------IEETGNLIQTIDVPD 417
>gi|225735591 RNA polymerase II associated protein 3 isoform 1 [Homo
sapiens]
Length = 665
Score = 79.3 bits (194), Expect = 1e-14
Identities = 72/295 (24%), Positives = 143/295 (48%), Gaps = 34/295 (11%)
Query: 3 ADKEKDLQKFLK-NVDEISNLIQEMNSDDPVVQQKAVLETEKRLLLMEED---------- 51
A+K +LQ +K N +E+ + ++++ + + ++QK +E ++ + EE+
Sbjct: 4 ANKAIELQLQVKQNAEELQDFMRDLENWEKDIKQKD-MELRRQNGVPEENLPPIRNGNFR 62
Query: 52 -QEEDECRTTLNKTMISPPQTAMKSAE-----EINSEAFLASVEKDAKERAKRRRENKVL 105
+++ + + + KT + +KS + +++ + L ++KD +E++
Sbjct: 63 KKKKGKAKESSKKTREENTKNRIKSYDYEAWAKLDVDRILDELDKDDSTHESLSQESESE 122
Query: 106 ADA----------LKEKGNEAFAEGNYETAILRYSEGLEKLKDMKVLYTNRAQAYMKLED 155
D LKEKGN+ F +G Y+ AI Y++G++ VL TNRA AY +L+
Sbjct: 123 EDGIHVDSQKALVLKEKGNKYFKQGKYDEAIDCYTKGMDADPYNPVLPTNRASAYFRLKK 182
Query: 156 YEKALVDCEWALKCDEKCTKAYFHMGKANLALKNYSVSRECYKKILEINPKLQTQVKGYL 215
+ A DC A+ + TKAY G A AL+ +++ Y+++LE+ P + L
Sbjct: 183 FAVAESDCNLAVALNRSYTKAYSRRGAARFALQKLEEAKKDYERVLELEPN-NFEATNEL 241
Query: 216 NQVD--LQEKADLQEKEAHELLDS--GKNTAV-TTKNLLETLSKPDQIPLFYAGG 265
++ L K + KEA ++ S G+ + +N + +S+ D+ F+ G
Sbjct: 242 RKISQALASKENSYPKEADIVIKSTEGERKQIEAQQNKQQAISEKDRGNGFFKEG 296
Score = 67.8 bits (164), Expect = 3e-11
Identities = 52/197 (26%), Positives = 90/197 (45%), Gaps = 25/197 (12%)
Query: 82 EAFLASVEKDAKERAKRRRENKVLADALKEKGNEAFAEGNYETAILRYSEGLEKLKDMKV 141
EA + + + + ++NK A + K++GN F EG YE AI Y+ G+ +
Sbjct: 258 EADIVIKSTEGERKQIEAQQNKQQAISEKDRGNGFFKEGKYERAIECYTRGIAADGANAL 317
Query: 142 LYTNRAQAYMKLEDYEKALVDCEWALKCDEKCTKAYFHMGKANLALKNYSVSRECYKKIL 201
L NRA AY+K++ YE+A DC A+ D +KA+ G A L + +++ ++ +L
Sbjct: 318 LPANRAMAYLKIQKYEEAEKDCTQAILLDGSYSKAFARRGTARTFLGKLNEAKQDFETVL 377
Query: 202 EINP------------KLQTQVKGYLNQVDLQEKADLQEKEAHELLDSGKNTAVT----- 244
+ P K + KG+ + V L Q + + +D+ + T
Sbjct: 378 LLEPGNKQAVTELSKIKKELIEKGHWDDVFLD---STQRQNVVKPIDNPPHPGSTKPLKK 434
Query: 245 -----TKNLLETLSKPD 256
T NL++T+ PD
Sbjct: 435 VIIEETGNLIQTIDVPD 451
>gi|5803181 stress-induced-phosphoprotein 1 (Hsp70/Hsp90-organizing
protein) [Homo sapiens]
Length = 543
Score = 79.0 bits (193), Expect = 1e-14
Identities = 47/167 (28%), Positives = 83/167 (49%), Gaps = 7/167 (4%)
Query: 89 EKDAKERAKRRRENKVLADALKEKGNEAFAEGNYETAILRYSEGLEKLKDMKVLYTNRAQ 148
EK KE+ + N LA K KGNE F +G+Y A+ Y+E +++ LY+NRA
Sbjct: 343 EKILKEQERLAYINPDLALEEKNKGNECFQKGDYPQAMKHYTEAIKRNPKDAKLYSNRAA 402
Query: 149 AYMKLEDYEKALVDCEWALKCDEKCTKAYFHMGKANLALKNYSVSRECYKKILEINPKLQ 208
Y KL +++ AL DCE ++ + K Y A A+K+Y+ + + Y+K L+++ +
Sbjct: 403 CYTKLLEFQLALKDCEECIQLEPTFIKGYTRKAAALEAMKDYTKAMDVYQKALDLDSSCK 462
Query: 209 TQVKGYLNQVDLQEKADLQEKEAHELLDSGKNTAVTTKNLLETLSKP 255
GY ++ + + H+ + K A+ + + +S P
Sbjct: 463 EAADGY-------QRCMMAQYNRHDSPEDVKRRAMADPEVQQIMSDP 502
Score = 53.1 bits (126), Expect = 8e-07
Identities = 35/103 (33%), Positives = 53/103 (51%), Gaps = 3/103 (2%)
Query: 109 LKEKGNEAFAEGNYETAILRYSEGLEKLKDMKVLYTNRAQAYMKLEDYEKALVDCEWALK 168
LKEKGN+A + GN + A+ YSE ++ VLY+NR+ AY K DY+KA D +
Sbjct: 7 LKEKGNKALSVGNIDDALQCYSEAIKLDPHNHVLYSNRSAAYAKKGDYQKAYEDGCKTVD 66
Query: 169 CDEKCTKAYFHMGKANLALKNYSVSRECYKKILE---INPKLQ 208
K Y A L + ++ Y++ L+ NP+L+
Sbjct: 67 LKPDWGKGYSRKAAALEFLNRFEEAKRTYEEGLKHEANNPQLK 109
Score = 50.1 bits (118), Expect = 7e-06
Identities = 50/207 (24%), Positives = 87/207 (42%), Gaps = 13/207 (6%)
Query: 10 QKFLKNVDEISNLIQEMNSD--------DPVVQQKAVLETEKRLLLMEEDQEEDECRTTL 61
+KF+ N + NL Q++ SD DP ++ + + + + ++ TTL
Sbjct: 122 RKFM-NPFNMPNLYQKLESDPRTRTLLSDPTYRE-LIEQLRNKPSDLGTKLQDPRIMTTL 179
Query: 62 NKTMISPPQTAMKSAEEINSEAFLASVEKDAKERAKRRR--ENKVLADALKEKGNEAFAE 119
+ ++ +M EEI + +K+ K ENK A KE GN+A+ +
Sbjct: 180 S-VLLGVDLGSMDEEEEIATPPPPPPPKKETKPEPMEEDLPENKKQALKEKELGNDAYKK 238
Query: 120 GNYETAILRYSEGLEKLKDMKVLYTNRAQAYMKLEDYEKALVDCEWALKCDEKCTKAYFH 179
+++TA+ Y + E TN+A Y + DY K CE A++ + + Y
Sbjct: 239 KDFDTALKHYDKAKELDPTNMTYITNQAAVYFEKGDYNKCRELCEKAIEVGRENREDYRQ 298
Query: 180 MGKANLALKNYSVSRECYKKILEINPK 206
+ KA + N E YK + K
Sbjct: 299 IAKAYARIGNSYFKEEKYKDAIHFYNK 325
>gi|4507711 tetratricopeptide repeat domain 1 [Homo sapiens]
Length = 292
Score = 78.2 bits (191), Expect = 2e-14
Identities = 64/218 (29%), Positives = 101/218 (46%), Gaps = 24/218 (11%)
Query: 7 KDLQKFLKNVDEISNLIQEMNSDDPVVQQKAVLETEKRLLL-----MEEDQEEDECRTTL 61
+DL LK D QE P V ++ +LL ++EDQ E+EC
Sbjct: 12 EDLLNGLKVTDT-----QEAECAGPPVPDPKNQHSQSKLLRDDEAHLQEDQGEEECFHDC 66
Query: 62 NKTMISPP---QTAMKSAEEINS----EAFLASVEKDAKERAKRRRENKVLADALKEKGN 114
+ + P + KS E++NS E +L +EK+ + K++R + + LKE+GN
Sbjct: 67 SASFEEEPGADKVENKSNEDVNSSELDEEYLIELEKNMSDEEKQKRREE--STRLKEEGN 124
Query: 115 EAFAEGNYETAILRYSEGLEKL-----KDMKVLYTNRAQAYMKLEDYEKALVDCEWALKC 169
E F +G+Y A YS LE K+ +L++NRA A MK + E A+ DC A++
Sbjct: 125 EQFKKGDYIEAESSYSRALEMCPSCFQKERSILFSNRAAARMKQDKKEMAINDCSKAIQL 184
Query: 170 DEKCTKAYFHMGKANLALKNYSVSRECYKKILEINPKL 207
+ +A + + E YK ILE +P +
Sbjct: 185 NPSYIRAILRRAELYEKTDKLDEALEDYKSILEKDPSI 222
>gi|21361356 translocase of outer mitochondrial membrane 34 [Homo
sapiens]
Length = 309
Score = 77.8 bits (190), Expect = 3e-14
Identities = 53/159 (33%), Positives = 78/159 (49%), Gaps = 11/159 (6%)
Query: 69 PQTAMKSAEEINSEAFLASVEKDAKERAKRRRENKVLADA-----LKEKGNEAFAEGNYE 123
P +A K + SE + +KE + D LKE+GNE +GN++
Sbjct: 151 PVSAQKRWNSLPSENHKEMAKSKSKETTATKNRVPSAGDVEKARVLKEEGNELVKKGNHK 210
Query: 124 TAILRYSEGLEKLKDMKVLYTNRAQAYMKLEDYEKALVDCEWALKCDEKCTKAYFHMGKA 183
AI +YSE L Y+NRA Y+ L+ Y +A+ DC ALK D K KA++ +A
Sbjct: 211 KAIEKYSESLLCSNLESATYSNRALCYLVLKQYTEAVKDCTEALKLDGKNVKAFYRRAQA 270
Query: 184 NLALKNYSVSRECYKKILEINP------KLQTQVKGYLN 216
+ ALK+Y S +L+I P KL+ +VK L+
Sbjct: 271 HKALKDYKSSFADISNLLQIEPRNGPAQKLRQEVKQNLH 309
Score = 50.1 bits (118), Expect = 7e-06
Identities = 33/115 (28%), Positives = 52/115 (45%), Gaps = 8/115 (6%)
Query: 107 DALKEKGNEAFAEGNYETAILRYSEGLEKLK--------DMKVLYTNRAQAYMKLEDYEK 158
+ L+ GNE+F G Y A Y L L+ + VLY+NRA ++K +
Sbjct: 10 EELRAAGNESFRNGQYAEASALYGRALRVLQAQGSSDPEEESVLYSNRAACHLKDGNCRD 69
Query: 159 ALVDCEWALKCDEKCTKAYFHMGKANLALKNYSVSRECYKKILEINPKLQTQVKG 213
+ DC AL K A AL+ Y ++ YK +L+I+ + + V+G
Sbjct: 70 CIKDCTSALALVPFSIKPLLRRASAYEALEKYPMAYVDYKTVLQIDDNVTSAVEG 124
>gi|24308141 small glutamine-rich tetratricopeptide repeat
(TPR)-containing, beta [Homo sapiens]
Length = 304
Score = 77.4 bits (189), Expect = 4e-14
Identities = 49/151 (32%), Positives = 76/151 (50%), Gaps = 2/151 (1%)
Query: 56 ECRTTLNKTMISPPQTAMKSAEEINSEAFLASVEKDAKERAKRRRENKVLADALKEKGNE 115
+C T+ K ISP T + ++ + + + D + E+ AD LK++GN
Sbjct: 37 QCLETVFK--ISPEDTHLAVSQPLTEMFTSSFCKNDVLPLSNSVPEDVGKADQLKDEGNN 94
Query: 116 AFAEGNYETAILRYSEGLEKLKDMKVLYTNRAQAYMKLEDYEKALVDCEWALKCDEKCTK 175
E NY A+ Y++ +E + V Y NRA A KL Y A+ DCE A+ D K +K
Sbjct: 95 HMKEENYAAAVDCYTQAIELDPNNAVYYCNRAAAQSKLGHYTDAIKDCEKAIAIDSKYSK 154
Query: 176 AYFHMGKANLALKNYSVSRECYKKILEINPK 206
AY MG A AL + + Y+K L+++P+
Sbjct: 155 AYGRMGLALTALNKFEEAVTSYQKALDLDPE 185
>gi|27262638 sperm associated antigen 1 [Homo sapiens]
Length = 926
Score = 72.0 bits (175), Expect = 2e-12
Identities = 61/205 (29%), Positives = 94/205 (45%), Gaps = 29/205 (14%)
Query: 40 ETEKRLLLMEEDQEEDECRTTLNKTMISPPQTAMKSAEEINSEAFLASVEKDAKERAKRR 99
+ EK L ++ED +E +T ++K+ +S +T + +A L EKD
Sbjct: 165 DVEKECLKIDEDYKE---KTVIDKSHLSKIETRIDTAG-------LTEKEKD-------- 206
Query: 100 RENKVLADALKEKGNEAFAEGNYETAILRYSEGLEKLKDMKVLYTNRAQAYMKLEDYEKA 159
LA KEKGNEAF G+YE A++ Y+ + L + V Y NRAQA +KL+++ A
Sbjct: 207 ----FLATREKEKGNEAFNSGDYEEAVMYYTRSISALPTV-VAYNNRAQAEIKLQNWNSA 261
Query: 160 LVDCEWALKCDEKCTKAYFHMGKANLALKNYSVSRECYKKILEINPKLQTQVKGYLNQVD 219
DCE L+ + KA + E K+L++ P K L++V+
Sbjct: 262 FQDCEKVLELEPGNVKALLRRATTYKHQNKLREATEDLSKVLDVEPD-NDLAKKTLSEVE 320
Query: 220 LQEKADLQEKE-AHELLDSGKNTAV 243
DL+ E A E GK +
Sbjct: 321 ----RDLKNSEAASETQTKGKRMVI 341
Score = 72.0 bits (175), Expect = 2e-12
Identities = 43/147 (29%), Positives = 80/147 (54%), Gaps = 6/147 (4%)
Query: 88 VEKDAKERAKRRRE---NKVLADALKEKGNEAFAEGNYETAILRYSEGLEKLKDMKVLYT 144
+ K A + + R++ ++ ALKE+GN+ + NY+ A+ +YSE L+ +YT
Sbjct: 602 ISKQAGDSSSHRQQGITDEKTFKALKEEGNQCVNDKNYKDALSKYSECLKINNKECAIYT 661
Query: 145 NRAQAYMKLEDYEKALVDCEWALKCDEKCTKAYFHMGKANLALKNYSVSRECYKKILEIN 204
NRA Y+KL +E+A DC+ AL+ + KA++ A+ LKNY S K++ ++
Sbjct: 662 NRALCYLKLCQFEEAKQDCDQALQLADGNVKAFYRRALAHKGLKNYQKSLIDLNKVILLD 721
Query: 205 PKLQTQVKGYLNQVDLQEKADLQEKEA 231
P + ++ + ++ +L++K A
Sbjct: 722 PSI---IEAKMELEEVTRLLNLKDKTA 745
Score = 52.0 bits (123), Expect = 2e-06
Identities = 33/108 (30%), Positives = 50/108 (46%), Gaps = 8/108 (7%)
Query: 109 LKEKGNEAFAEGNYETAILRYSEGLEKLK--------DMKVLYTNRAQAYMKLEDYEKAL 160
LK +GNE F G + A +YS + L+ D+ +LY+NRA Y+K + +
Sbjct: 448 LKSQGNELFRSGQFAEAAGKYSAAIALLEPAGSEIADDLSILYSNRAACYLKEGNCSGCI 507
Query: 161 VDCEWALKCDEKCTKAYFHMGKANLALKNYSVSRECYKKILEINPKLQ 208
DC AL+ K A L+ Y + YK +L+I+ LQ
Sbjct: 508 QDCNRALELHPFSMKPLLRRAMAYETLEQYGKAYVDYKTVLQIDCGLQ 555
>gi|27262636 sperm associated antigen 1 [Homo sapiens]
Length = 926
Score = 72.0 bits (175), Expect = 2e-12
Identities = 61/205 (29%), Positives = 94/205 (45%), Gaps = 29/205 (14%)
Query: 40 ETEKRLLLMEEDQEEDECRTTLNKTMISPPQTAMKSAEEINSEAFLASVEKDAKERAKRR 99
+ EK L ++ED +E +T ++K+ +S +T + +A L EKD
Sbjct: 165 DVEKECLKIDEDYKE---KTVIDKSHLSKIETRIDTAG-------LTEKEKD-------- 206
Query: 100 RENKVLADALKEKGNEAFAEGNYETAILRYSEGLEKLKDMKVLYTNRAQAYMKLEDYEKA 159
LA KEKGNEAF G+YE A++ Y+ + L + V Y NRAQA +KL+++ A
Sbjct: 207 ----FLATREKEKGNEAFNSGDYEEAVMYYTRSISALPTV-VAYNNRAQAEIKLQNWNSA 261
Query: 160 LVDCEWALKCDEKCTKAYFHMGKANLALKNYSVSRECYKKILEINPKLQTQVKGYLNQVD 219
DCE L+ + KA + E K+L++ P K L++V+
Sbjct: 262 FQDCEKVLELEPGNVKALLRRATTYKHQNKLREATEDLSKVLDVEPD-NDLAKKTLSEVE 320
Query: 220 LQEKADLQEKE-AHELLDSGKNTAV 243
DL+ E A E GK +
Sbjct: 321 ----RDLKNSEAASETQTKGKRMVI 341
Score = 72.0 bits (175), Expect = 2e-12
Identities = 43/147 (29%), Positives = 80/147 (54%), Gaps = 6/147 (4%)
Query: 88 VEKDAKERAKRRRE---NKVLADALKEKGNEAFAEGNYETAILRYSEGLEKLKDMKVLYT 144
+ K A + + R++ ++ ALKE+GN+ + NY+ A+ +YSE L+ +YT
Sbjct: 602 ISKQAGDSSSHRQQGITDEKTFKALKEEGNQCVNDKNYKDALSKYSECLKINNKECAIYT 661
Query: 145 NRAQAYMKLEDYEKALVDCEWALKCDEKCTKAYFHMGKANLALKNYSVSRECYKKILEIN 204
NRA Y+KL +E+A DC+ AL+ + KA++ A+ LKNY S K++ ++
Sbjct: 662 NRALCYLKLCQFEEAKQDCDQALQLADGNVKAFYRRALAHKGLKNYQKSLIDLNKVILLD 721
Query: 205 PKLQTQVKGYLNQVDLQEKADLQEKEA 231
P + ++ + ++ +L++K A
Sbjct: 722 PSI---IEAKMELEEVTRLLNLKDKTA 745
Score = 52.0 bits (123), Expect = 2e-06
Identities = 33/108 (30%), Positives = 50/108 (46%), Gaps = 8/108 (7%)
Query: 109 LKEKGNEAFAEGNYETAILRYSEGLEKLK--------DMKVLYTNRAQAYMKLEDYEKAL 160
LK +GNE F G + A +YS + L+ D+ +LY+NRA Y+K + +
Sbjct: 448 LKSQGNELFRSGQFAEAAGKYSAAIALLEPAGSEIADDLSILYSNRAACYLKEGNCSGCI 507
Query: 161 VDCEWALKCDEKCTKAYFHMGKANLALKNYSVSRECYKKILEINPKLQ 208
DC AL+ K A L+ Y + YK +L+I+ LQ
Sbjct: 508 QDCNRALELHPFSMKPLLRRAMAYETLEQYGKAYVDYKTVLQIDCGLQ 555
>gi|4506921 small glutamine-rich tetratricopeptide [Homo sapiens]
Length = 313
Score = 70.5 bits (171), Expect = 5e-12
Identities = 42/115 (36%), Positives = 60/115 (52%)
Query: 95 RAKRRRENKVLADALKEKGNEAFAEGNYETAILRYSEGLEKLKDMKVLYTNRAQAYMKLE 154
R E+ A+ LK +GNE N+E A+ Y + +E V + NRA AY KL
Sbjct: 80 RTPPSEEDSAEAERLKTEGNEQMKVENFEAAVHFYGKAIELNPANAVYFCNRAAAYSKLG 139
Query: 155 DYEKALVDCEWALKCDEKCTKAYFHMGKANLALKNYSVSRECYKKILEINPKLQT 209
+Y A+ DCE A+ D +KAY MG A +L + + YKK LE++P +T
Sbjct: 140 NYAGAVQDCERAICIDPAYSKAYGRMGLALSSLNKHVEAVAYYKKALELDPDNET 194
>gi|225735595 RNA polymerase II associated protein 3 isoform 3 [Homo
sapiens]
Length = 506
Score = 67.8 bits (164), Expect = 3e-11
Identities = 52/197 (26%), Positives = 90/197 (45%), Gaps = 25/197 (12%)
Query: 82 EAFLASVEKDAKERAKRRRENKVLADALKEKGNEAFAEGNYETAILRYSEGLEKLKDMKV 141
EA + + + + ++NK A + K++GN F EG YE AI Y+ G+ +
Sbjct: 99 EADIVIKSTEGERKQIEAQQNKQQAISEKDRGNGFFKEGKYERAIECYTRGIAADGANAL 158
Query: 142 LYTNRAQAYMKLEDYEKALVDCEWALKCDEKCTKAYFHMGKANLALKNYSVSRECYKKIL 201
L NRA AY+K++ YE+A DC A+ D +KA+ G A L + +++ ++ +L
Sbjct: 159 LPANRAMAYLKIQKYEEAEKDCTQAILLDGSYSKAFARRGTARTFLGKLNEAKQDFETVL 218
Query: 202 EINP------------KLQTQVKGYLNQVDLQEKADLQEKEAHELLDSGKNTAVT----- 244
+ P K + KG+ + V L Q + + +D+ + T
Sbjct: 219 LLEPGNKQAVTELSKIKKELIEKGHWDDVFLD---STQRQNVVKPIDNPPHPGSTKPLKK 275
Query: 245 -----TKNLLETLSKPD 256
T NL++T+ PD
Sbjct: 276 VIIEETGNLIQTIDVPD 292
Score = 52.0 bits (123), Expect = 2e-06
Identities = 38/130 (29%), Positives = 65/130 (50%), Gaps = 6/130 (4%)
Query: 141 VLYTNRAQAYMKLEDYEKALVDCEWALKCDEKCTKAYFHMGKANLALKNYSVSRECYKKI 200
VL TNRA AY +L+ + A DC A+ + TKAY G A AL+ +++ Y+++
Sbjct: 9 VLPTNRASAYFRLKKFAVAESDCNLAVALNRSYTKAYSRRGAARFALQKLEEAKKDYERV 68
Query: 201 LEINPKLQTQVKGYLNQVD--LQEKADLQEKEAHELLDS--GKNTAV-TTKNLLETLSKP 255
LE+ P + L ++ L K + KEA ++ S G+ + +N + +S+
Sbjct: 69 LELEPN-NFEATNELRKISQALASKENSYPKEADIVIKSTEGERKQIEAQQNKQQAISEK 127
Query: 256 DQIPLFYAGG 265
D+ F+ G
Sbjct: 128 DRGNGFFKEG 137
>gi|56181387 STIP1 homology and U-box containing protein 1 [Homo
sapiens]
Length = 303
Score = 67.4 bits (163), Expect = 4e-11
Identities = 33/90 (36%), Positives = 50/90 (55%)
Query: 101 ENKVLADALKEKGNEAFAEGNYETAILRYSEGLEKLKDMKVLYTNRAQAYMKLEDYEKAL 160
E A LKE+GN F Y A Y + + + V YTNRA Y+K++ +E+AL
Sbjct: 21 EKSPSAQELKEQGNRLFVGRKYPEAAACYGRAITRNPLVAVYYTNRALCYLKMQQHEQAL 80
Query: 161 VDCEWALKCDEKCTKAYFHMGKANLALKNY 190
DC AL+ D + KA+F +G+ L +++Y
Sbjct: 81 ADCRRALELDGQSVKAHFFLGQCQLEMESY 110
>gi|224809329 FK506 binding protein 5 isoform 1 [Homo sapiens]
Length = 457
Score = 65.9 bits (159), Expect = 1e-10
Identities = 48/178 (26%), Positives = 80/178 (44%), Gaps = 19/178 (10%)
Query: 48 MEEDQEEDECRTTLNKTM----ISPPQTAMKSAEEINSEAFLASVEKDAKERAKRRRENK 103
+E+ Q E++C L P+ ++ E+ E L S EK + +E
Sbjct: 206 LEKMQREEQCILYLGPRYGFGEAGKPKFGIEPNAELIYEVTLKSFEKAKESWEMDTKEKL 265
Query: 104 VLADALKEKGNEAFAEGNYETAILRY-------------SEGLEKLKDMKVL--YTNRAQ 148
A +KEKG F G Y A+++Y SE K + +L + N A
Sbjct: 266 EQAAIVKEKGTVYFKGGKYMQAVIQYGKIVSWLEMEYGLSEKESKASESFLLAAFLNLAM 325
Query: 149 AYMKLEDYEKALVDCEWALKCDEKCTKAYFHMGKANLALKNYSVSRECYKKILEINPK 206
Y+KL +Y KA+ C+ AL D K + G+A L + + ++ ++K+LE+NP+
Sbjct: 326 CYLKLREYTKAVECCDKALGLDSANEKGLYRRGEAQLLMNEFESAKGDFEKVLEVNPQ 383
>gi|224809327 FK506 binding protein 5 isoform 1 [Homo sapiens]
Length = 457
Score = 65.9 bits (159), Expect = 1e-10
Identities = 48/178 (26%), Positives = 80/178 (44%), Gaps = 19/178 (10%)
Query: 48 MEEDQEEDECRTTLNKTM----ISPPQTAMKSAEEINSEAFLASVEKDAKERAKRRRENK 103
+E+ Q E++C L P+ ++ E+ E L S EK + +E
Sbjct: 206 LEKMQREEQCILYLGPRYGFGEAGKPKFGIEPNAELIYEVTLKSFEKAKESWEMDTKEKL 265
Query: 104 VLADALKEKGNEAFAEGNYETAILRY-------------SEGLEKLKDMKVL--YTNRAQ 148
A +KEKG F G Y A+++Y SE K + +L + N A
Sbjct: 266 EQAAIVKEKGTVYFKGGKYMQAVIQYGKIVSWLEMEYGLSEKESKASESFLLAAFLNLAM 325
Query: 149 AYMKLEDYEKALVDCEWALKCDEKCTKAYFHMGKANLALKNYSVSRECYKKILEINPK 206
Y+KL +Y KA+ C+ AL D K + G+A L + + ++ ++K+LE+NP+
Sbjct: 326 CYLKLREYTKAVECCDKALGLDSANEKGLYRRGEAQLLMNEFESAKGDFEKVLEVNPQ 383
>gi|4758384 FK506 binding protein 5 isoform 1 [Homo sapiens]
Length = 457
Score = 65.9 bits (159), Expect = 1e-10
Identities = 48/178 (26%), Positives = 80/178 (44%), Gaps = 19/178 (10%)
Query: 48 MEEDQEEDECRTTLNKTM----ISPPQTAMKSAEEINSEAFLASVEKDAKERAKRRRENK 103
+E+ Q E++C L P+ ++ E+ E L S EK + +E
Sbjct: 206 LEKMQREEQCILYLGPRYGFGEAGKPKFGIEPNAELIYEVTLKSFEKAKESWEMDTKEKL 265
Query: 104 VLADALKEKGNEAFAEGNYETAILRY-------------SEGLEKLKDMKVL--YTNRAQ 148
A +KEKG F G Y A+++Y SE K + +L + N A
Sbjct: 266 EQAAIVKEKGTVYFKGGKYMQAVIQYGKIVSWLEMEYGLSEKESKASESFLLAAFLNLAM 325
Query: 149 AYMKLEDYEKALVDCEWALKCDEKCTKAYFHMGKANLALKNYSVSRECYKKILEINPK 206
Y+KL +Y KA+ C+ AL D K + G+A L + + ++ ++K+LE+NP+
Sbjct: 326 CYLKLREYTKAVECCDKALGLDSANEKGLYRRGEAQLLMNEFESAKGDFEKVLEVNPQ 383
>gi|5453958 protein phosphatase 5, catalytic subunit [Homo sapiens]
Length = 499
Score = 64.3 bits (155), Expect = 4e-10
Identities = 32/100 (32%), Positives = 55/100 (55%)
Query: 106 ADALKEKGNEAFAEGNYETAILRYSEGLEKLKDMKVLYTNRAQAYMKLEDYEKALVDCEW 165
A+ LK + N+ F +YE AI YS+ +E + Y NR+ AY++ E Y AL D
Sbjct: 28 AEELKTQANDYFKAKDYENAIKFYSQAIELNPSNAIYYGNRSLAYLRTECYGYALGDATR 87
Query: 166 ALKCDEKCTKAYFHMGKANLALKNYSVSRECYKKILEINP 205
A++ D+K K Y+ +N+AL + + Y+ ++++ P
Sbjct: 88 AIELDKKYIKGYYRRAASNMALGKFRAALRDYETVVKVKP 127
>gi|4503729 FK506 binding protein 52 [Homo sapiens]
Length = 459
Score = 63.9 bits (154), Expect = 5e-10
Identities = 42/144 (29%), Positives = 75/144 (52%), Gaps = 17/144 (11%)
Query: 78 EINSEAFLASVEKDAKERAKRRRENKVLADAL-KEKGNEAFAEGNYETAILRY------- 129
E+ E L S EK AKE + E K+ + KE+G F EG Y+ A+L+Y
Sbjct: 242 ELKYELHLKSFEK-AKESWEMNSEEKLEQSTIVKERGTVYFKEGKYKQALLQYKKIVSWL 300
Query: 130 -------SEGLEKLKDMKVL-YTNRAQAYMKLEDYEKALVDCEWALKCDEKCTKAYFHMG 181
+E +K + +++ + N A ++KL+ + A+ C AL+ D K F G
Sbjct: 301 EYESSFSNEEAQKAQALRLASHLNLAMCHLKLQAFSAAIESCNKALELDSNNEKGLFRRG 360
Query: 182 KANLALKNYSVSRECYKKILEINP 205
+A+LA+ ++ ++R ++K+L++ P
Sbjct: 361 EAHLAVNDFELARADFQKVLQLYP 384
>gi|221219056 DnaJ (Hsp40) homolog, subfamily C, member 7 isoform 2
[Homo sapiens]
Length = 438
Score = 61.6 bits (148), Expect = 2e-09
Identities = 45/153 (29%), Positives = 70/153 (45%), Gaps = 7/153 (4%)
Query: 94 ERAKRRRENKVLADALKEKGNEAFAEGNYETAILRYSEGL----EKLKDMKVLYTNRAQA 149
E+A N A KE GN+AF EGNY+ A Y+E L +K LY NR
Sbjct: 188 EKACIACRNAKALKAKKEDGNKAFKEGNYKLAYELYTEALGIDPNNIKTNAKLYCNRGTV 247
Query: 150 YMKLEDYEKALVDCEWALKCDEKCTKAYFHMGKANLALKNYSVSRECYKKILEINPKLQT 209
KL + A+ DC A+K D+ KAY + + + Y + Y+K+ + +
Sbjct: 248 NSKLRKLDDAIEDCTNAVKLDDTYIKAYLRRAQCYMDTEQYEEAVRDYEKVYQ--TEKTK 305
Query: 210 QVKGYLNQVDLQEKADLQEKEAHELLDSGKNTA 242
+ K L L+ K + K+ +++L KN +
Sbjct: 306 EHKQLLKNAQLELKKS-KRKDYYKILGVDKNAS 337
Score = 38.5 bits (88), Expect = 0.022
Identities = 21/88 (23%), Positives = 43/88 (48%)
Query: 143 YTNRAQAYMKLEDYEKALVDCEWALKCDEKCTKAYFHMGKANLALKNYSVSRECYKKILE 202
Y NRA M L + +AL D + +++ D+ + + GK +L+L N + +++ LE
Sbjct: 9 YGNRAATLMMLGRFREALGDAQQSVRLDDSFVRGHLREGKCHLSLGNAMAACRSFQRALE 68
Query: 203 INPKLQTQVKGYLNQVDLQEKADLQEKE 230
++ K + + N + E + E +
Sbjct: 69 LDHKNAQAQQEFKNANAVMEYEKIAETD 96
>gi|54607135 translocase of outer mitochondrial membrane 70 homolog
A [Homo sapiens]
Length = 608
Score = 61.6 bits (148), Expect = 2e-09
Identities = 36/103 (34%), Positives = 54/103 (52%), Gaps = 8/103 (7%)
Query: 106 ADALKEKGNEAFAEGNYETAILRYSEGL-----EKLKDMKVLYTNRAQAYMKLEDYEKAL 160
A A K KGN+ F G YE AI Y+E + EK D+ Y NRA A+ +L+ +++
Sbjct: 114 AQAAKNKGNKYFKAGKYEQAIQCYTEAISLCPTEKNVDLSTFYQNRAAAFEQLQKWKEVA 173
Query: 161 VDCEWALKCDEKCTKAYFHMGKANLALKNYSVSRECYKKILEI 203
DC A++ + K KA F KA+ L N +EC + + +
Sbjct: 174 QDCTKAVELNPKYVKALFRRAKAHEKLDN---KKECLEDVTAV 213
>gi|221219053 DnaJ (Hsp40) homolog, subfamily C, member 7 isoform 1
[Homo sapiens]
Length = 494
Score = 60.8 bits (146), Expect = 4e-09
Identities = 43/153 (28%), Positives = 71/153 (46%), Gaps = 7/153 (4%)
Query: 94 ERAKRRRENKVLADALKEKGNEAFAEGNYETAILRYSEGL----EKLKDMKVLYTNRAQA 149
E+A N A KE GN+AF EGNY+ A Y+E L +K LY NR
Sbjct: 244 EKACIACRNAKALKAKKEDGNKAFKEGNYKLAYELYTEALGIDPNNIKTNAKLYCNRGTV 303
Query: 150 YMKLEDYEKALVDCEWALKCDEKCTKAYFHMGKANLALKNYSVSRECYKKILEINPKLQT 209
KL + A+ DC A+K D+ KAY + + + Y + Y+K+ + +
Sbjct: 304 NSKLRKLDDAIEDCTNAVKLDDTYIKAYLRRAQCYMDTEQYEEAVRDYEKVYQTEKTKEH 363
Query: 210 QVKGYLNQVDLQEKADLQEKEAHELLDSGKNTA 242
+ Q++L++ + K+ +++L KN +
Sbjct: 364 KQLLKNAQLELRKS---KRKDYYKILGVDKNAS 393
Score = 56.6 bits (135), Expect = 8e-08
Identities = 34/149 (22%), Positives = 72/149 (48%), Gaps = 4/149 (2%)
Query: 82 EAFLASVEKDAKERAKRRRENKVLADALKEKGNEAFAEGNYETAILRYSEGLEKLKDMKV 141
+ +A+ E + + + +RE A+ KE+GN +A+ +Y A Y++ ++
Sbjct: 8 DVVMAATEPELLDDQEAKRE----AETFKEQGNAYYAKKDYNEAYNYYTKAIDMCPKNAS 63
Query: 142 LYTNRAQAYMKLEDYEKALVDCEWALKCDEKCTKAYFHMGKANLALKNYSVSRECYKKIL 201
Y NRA M L + +AL D + +++ D+ + + GK +L+L N + +++ L
Sbjct: 64 YYGNRAATLMMLGRFREALGDAQQSVRLDDSFVRGHLREGKCHLSLGNAMAACRSFQRAL 123
Query: 202 EINPKLQTQVKGYLNQVDLQEKADLQEKE 230
E++ K + + N + E + E +
Sbjct: 124 ELDHKNAQAQQEFKNANAVMEYEKIAETD 152
>gi|224028289 tetratricopeptide repeat domain 28 [Homo sapiens]
Length = 2481
Score = 59.3 bits (142), Expect = 1e-08
Identities = 34/95 (35%), Positives = 53/95 (55%)
Query: 112 KGNEAFAEGNYETAILRYSEGLEKLKDMKVLYTNRAQAYMKLEDYEKALVDCEWALKCDE 171
+ N+A +G++ TAI+ Y+E L +LY+NR+ AYMK++ Y+KAL D A +
Sbjct: 64 QSNQACHDGDFHTAIVLYNEALAVDPQNCILYSNRSAAYMKIQQYDKALDDAIKARLLNP 123
Query: 172 KCTKAYFHMGKANLALKNYSVSRECYKKILEINPK 206
K KAYF G A L ++ + + L +PK
Sbjct: 124 KWPKAYFRQGVALQYLGRHADALAAFASGLAQDPK 158
Score = 37.0 bits (84), Expect = 0.063
Identities = 37/125 (29%), Positives = 57/125 (45%), Gaps = 14/125 (11%)
Query: 96 AKRRRENKVLADALKEKGNEAFAEGNYETAILRYSEGLEKLKDM-------KVLYTNRAQ 148
A+ R+ + A AL GN + G Y A Y + L D+ KV + N
Sbjct: 584 ARELRDIQSEARALSNLGNFHCSRGEYVQAAPYYEQYLRLAPDLQDMEGEGKVCH-NLGY 642
Query: 149 AYMKLEDYEKALV----DCEWALKCDEKCT--KAYFHMGKANLALKNYSVSRECYKKILE 202
A+ L +Y++A+ D A +K + KAY ++G A AL N+S + EC K +L
Sbjct: 643 AHYCLGNYQEAVKYYEQDLALAKDLHDKLSQAKAYCNLGLAFKALLNFSKAEECQKYLLS 702
Query: 203 INPKL 207
+ L
Sbjct: 703 LAQSL 707
Score = 33.1 bits (74), Expect = 0.91
Identities = 26/99 (26%), Positives = 42/99 (42%), Gaps = 6/99 (6%)
Query: 115 EAFAEGNYETAILRYSEGLEKLKDMKVLYTNRAQAYMKLEDYEKALVDCEWALKCDEKC- 173
EA + A+L+ G E + D Y N Y L DYE+A+ E L +
Sbjct: 852 EAIGYFEQQLAMLQQLSGNESVLDRGRAYGNLGDCYEALGDYEEAIKYYEQYLSVAQSLN 911
Query: 174 -----TKAYFHMGKANLALKNYSVSRECYKKILEINPKL 207
KAY +G + A+ + + C++K L + +L
Sbjct: 912 RMQDQAKAYRGLGNGHRAMGSLQQALVCFEKRLVVAHEL 950
Score = 33.1 bits (74), Expect = 0.91
Identities = 27/99 (27%), Positives = 45/99 (45%), Gaps = 14/99 (14%)
Query: 118 AEGNYETAILRYSEGLEKLKDMKVLYTNRAQAYMKLEDYEKALVDCEWALKCDEK----- 172
A G+YE AI Y + L + + + ++A+AY L + +A+ + AL C EK
Sbjct: 889 ALGDYEEAIKYYEQYLSVAQSLNRMQ-DQAKAYRGLGNGHRAMGSLQQALVCFEKRLVVA 947
Query: 173 --------CTKAYFHMGKANLALKNYSVSRECYKKILEI 203
+AY +G + L NY + C ++ L I
Sbjct: 948 HELGEAFNKAQAYGELGSLHSQLGNYEQAISCLERQLNI 986
>gi|73747840 LON peptidase N-terminal domain and ring finger 3
isoform 1 [Homo sapiens]
Length = 759
Score = 56.2 bits (134), Expect = 1e-07
Identities = 32/92 (34%), Positives = 49/92 (53%), Gaps = 7/92 (7%)
Query: 106 ADALKEKGNEAFAEGNYETAILRYSEGLEKLKDMKVLYTNRAQAYMKLEDYEKALVDCEW 165
A L+ +GN + E E A+L+Y+E ++ + +LY+NR+Q Y LE +E AL D E
Sbjct: 243 ASQLRHEGNRLYRERQVEAALLKYNEAVKLAPNDHLLYSNRSQIYFTLESHENALHDAEI 302
Query: 166 ALKCDEKCTKAYFH-------MGKANLALKNY 190
A K KA+F +GK AL+ +
Sbjct: 303 ACKLRPMGFKAHFRKAQALATLGKVEEALREF 334
>gi|156627581 tetratricopeptide repeat domain 4 [Homo sapiens]
Length = 387
Score = 53.9 bits (128), Expect = 5e-07
Identities = 41/144 (28%), Positives = 75/144 (52%), Gaps = 6/144 (4%)
Query: 106 ADALKEKGNEAFAEGNYETAILRYSEGLEKL---KDMK-VLYTNRAQAYMKLEDYEKALV 161
A K++GN+ F E +Y+ A++ Y+EGL+K D+ VLYTNRA A L ++ AL
Sbjct: 79 AKTYKDEGNDYFKEKDYKKAVISYTEGLKKKCADPDLNAVLYTNRAAAQYYLGNFRSALN 138
Query: 162 DCEWALKCDEKCTKAYFHMGKANLALKNYSVSRECYKKILEINPKLQ--TQVKGYLNQVD 219
D A K KA +L LK+++ + + L+I+ K + +++ +++
Sbjct: 139 DVTAARKLKPCHLKAIIRGALCHLELKHFAEAVNWCDEGLQIDAKEKKLLEMRAKADKLK 198
Query: 220 LQEKADLQEKEAHELLDSGKNTAV 243
E+ D+++ E + +N A+
Sbjct: 199 RIEQRDVRKANLKEKKERNQNEAL 222
>gi|75750484 cardiomyopathy associated 4 isoform 2 [Homo sapiens]
Length = 929
Score = 53.9 bits (128), Expect = 5e-07
Identities = 107/452 (23%), Positives = 170/452 (37%), Gaps = 86/452 (19%)
Query: 103 KVLADALKEKGNEAFAEGNYETAILRYSEGLEKLKD---MKVLYTNRAQAYMKLEDYEKA 159
+V A LKE+GN F +Y+ A YS+ L+ KD + LY NRA +K E Y +A
Sbjct: 3 EVEAVQLKEEGNRHFQLQDYKAATNSYSQALKLTKDKALLATLYRNRAACGLKTESYVQA 62
Query: 160 LVDCEWALKCDEKCTKAYF-------HMGKANLALK-----------NYSVSRECYKKIL 201
D A+ + KA + H+GK + A K N + +
Sbjct: 63 ASDASRAIDINSSDIKALYRRCQALEHLGKLDQAFKDVQRCATLEPRNQNFQEMLRRLNT 122
Query: 202 EINPKLQTQV-------KGYLNQVDLQEKADLQEKEAHELLDSGKNTAVTTKNLLETLSK 254
I KL+ Q K + +D +AD +EK A+ L+ G+ A K
Sbjct: 123 SIQEKLRVQFSTDSRVQKMFEILLDENSEADKREKAANNLIVLGREEAGAEK-------- 174
Query: 255 PDQIPLFYAGGIEILTEMINE-------CTEQTLFRMHNGFS-----IISDNEVIRRCFS 302
+F G+ +L ++++ +TL M +G I+ + R C
Sbjct: 175 -----IFQNNGVALLLQLLDTKKPELVLAAVRTLSGMCSGHQARATVILHAVRIDRICSL 229
Query: 303 TAGNDAVEEMVCVSVLKLWQAVC-SRNEENQRVLVIHHDRARLLAALLSSKVLAIRQQSF 361
A E + ++V L QA+ S + E++R H + L + I
Sbjct: 230 MA---VENEEMSLAVCNLLQAIIDSLSGEDKRE---HRGKEEALVLDTKKDLKQITSHLL 283
Query: 362 ALLLHLAQTESGRSLIINHLDLTRLLEALVSFLDFSDKEANTAMGLFTDLALEERFQVWF 421
+L+ + GR +N LL V D + + N+ D L + +V
Sbjct: 284 DMLVSKKVSGQGRDQALN------LLNKNVPRKDLAIHD-NSRTIYVVDNGLRKILKVVG 336
Query: 422 QA-NLPGVLPALTGVLKTDPKVSSSSALCQCIAIMGNLSAEPTTRRHMAACEEFGDGCLS 480
Q +LP LP TD +S L + +L +P CEE+ G
Sbjct: 337 QVPDLPSCLPL------TDNTRMLASILIN--KLYDDLRCDPERDHFRKICEEYITGKFD 388
Query: 481 LLARCEEDVDLFREVIYTLLGLMMNLCLQAPF 512
+D+D I T+ G+ LQ PF
Sbjct: 389 -----PQDMDKNLNAIQTVSGI-----LQGPF 410
>gi|27477061 cardiomyopathy associated 4 isoform 1 [Homo sapiens]
Length = 931
Score = 53.9 bits (128), Expect = 5e-07
Identities = 107/452 (23%), Positives = 170/452 (37%), Gaps = 86/452 (19%)
Query: 103 KVLADALKEKGNEAFAEGNYETAILRYSEGLEKLKD---MKVLYTNRAQAYMKLEDYEKA 159
+V A LKE+GN F +Y+ A YS+ L+ KD + LY NRA +K E Y +A
Sbjct: 3 EVEAVQLKEEGNRHFQLQDYKAATNSYSQALKLTKDKALLATLYRNRAACGLKTESYVQA 62
Query: 160 LVDCEWALKCDEKCTKAYF-------HMGKANLALK-----------NYSVSRECYKKIL 201
D A+ + KA + H+GK + A K N + +
Sbjct: 63 ASDASRAIDINSSDIKALYRRCQALEHLGKLDQAFKDVQRCATLEPRNQNFQEMLRRLNT 122
Query: 202 EINPKLQTQV-------KGYLNQVDLQEKADLQEKEAHELLDSGKNTAVTTKNLLETLSK 254
I KL+ Q K + +D +AD +EK A+ L+ G+ A K
Sbjct: 123 SIQEKLRVQFSTDSRVQKMFEILLDENSEADKREKAANNLIVLGREEAGAEK-------- 174
Query: 255 PDQIPLFYAGGIEILTEMINE-------CTEQTLFRMHNGFS-----IISDNEVIRRCFS 302
+F G+ +L ++++ +TL M +G I+ + R C
Sbjct: 175 -----IFQNNGVALLLQLLDTKKPELVLAAVRTLSGMCSGHQARATVILHAVRIDRICSL 229
Query: 303 TAGNDAVEEMVCVSVLKLWQAVC-SRNEENQRVLVIHHDRARLLAALLSSKVLAIRQQSF 361
A E + ++V L QA+ S + E++R H + L + I
Sbjct: 230 MA---VENEEMSLAVCNLLQAIIDSLSGEDKRE---HRGKEEALVLDTKKDLKQITSHLL 283
Query: 362 ALLLHLAQTESGRSLIINHLDLTRLLEALVSFLDFSDKEANTAMGLFTDLALEERFQVWF 421
+L+ + GR +N LL V D + + N+ D L + +V
Sbjct: 284 DMLVSKKVSGQGRDQALN------LLNKNVPRKDLAIHD-NSRTIYVVDNGLRKILKVVG 336
Query: 422 QA-NLPGVLPALTGVLKTDPKVSSSSALCQCIAIMGNLSAEPTTRRHMAACEEFGDGCLS 480
Q +LP LP TD +S L + +L +P CEE+ G
Sbjct: 337 QVPDLPSCLPL------TDNTRMLASILIN--KLYDDLRCDPERDHFRKICEEYITGKFD 388
Query: 481 LLARCEEDVDLFREVIYTLLGLMMNLCLQAPF 512
+D+D I T+ G+ LQ PF
Sbjct: 389 -----PQDMDKNLNAIQTVSGI-----LQGPF 410
>gi|75677570 dyslexia susceptibility 1 candidate 1 isoform a [Homo
sapiens]
Length = 420
Score = 53.5 bits (127), Expect = 6e-07
Identities = 44/152 (28%), Positives = 68/152 (44%), Gaps = 20/152 (13%)
Query: 71 TAMKSAEEINSEAFLASVEKDAKERAKRRRENKVLADA---------LKEKGNEAFAEGN 121
TA++ ++ E +L K A+ R + L D LK+KGN+ FA N
Sbjct: 249 TALRESQVAEEEEWL---HKQAEARRAMNTDIAELCDLKEEEKNPEWLKDKGNKLFATEN 305
Query: 122 YETAILRYSEGLEKLKDMKVLYTNRAQAYMKLEDYEKALVDCEWALKC--------DEKC 173
Y AI Y+ + M +LY NRA ++KL++ KA+ D AL+
Sbjct: 306 YLAAINAYNLAIRLNNKMPLLYLNRAACHLKLKNLHKAIEDSSKALELLMPPVTDNANAR 365
Query: 174 TKAYFHMGKANLALKNYSVSRECYKKILEINP 205
KA+ G A L+ Y + Y+ L+I+P
Sbjct: 366 MKAHVRRGTAFCQLELYVEGLQDYEAALKIDP 397
>gi|22095349 WD and tetratricopeptide repeats 1 [Homo sapiens]
Length = 676
Score = 53.1 bits (126), Expect = 8e-07
Identities = 32/93 (34%), Positives = 51/93 (54%), Gaps = 3/93 (3%)
Query: 107 DALKEKGNEAFAEGNYETAILRYSEGLEKLKDMKVLYTNRAQAYMKLE---DYEKALVDC 163
+ +K++ NEAFA + AI YS+ +++ +LY NRA AYMK + D+ AL DC
Sbjct: 362 ERVKQQANEAFACQQWTQAIQLYSKAVQRAPHNAMLYGNRAAAYMKRKWDGDHYDALRDC 421
Query: 164 EWALKCDEKCTKAYFHMGKANLALKNYSVSREC 196
A+ + KA+F + + LK + + EC
Sbjct: 422 LKAISLNPCHLKAHFRLARCLFELKYVAEALEC 454
>gi|37622896 LON peptidase N-terminal domain and ring finger 3
isoform 2 [Homo sapiens]
Length = 718
Score = 52.4 bits (124), Expect = 1e-06
Identities = 39/125 (31%), Positives = 62/125 (49%), Gaps = 9/125 (7%)
Query: 106 ADALKEKGNEAFAEGNYETAILRYSEGLEKLKDMKVLYTNRAQAYMKLEDYEKALVDCEW 165
A L+ +GN + E E A+L+Y+E ++ + +LY+NR+Q Y LE +E AL D E
Sbjct: 243 ASQLRHEGNRLYRERQVEAALLKYNEAVKLAPNDHLLYSNRSQIYFTLESHENALHDAEI 302
Query: 166 ALKCDEKCTKAYFHMG-KANLALKNYSVSRECYKKILEINPKLQTQVKGYLNQVDLQEKA 224
A K MG K NL L + S E + + +VKG Q ++++
Sbjct: 303 ACKLRP--------MGFKDNLELPHCSSQEEAAARGDGSSLMDPAKVKGDGQQHHMKDQE 354
Query: 225 DLQEK 229
+ +EK
Sbjct: 355 EEEEK 359
>gi|89179321 smooth muscle cell associated protein-1 isoform 3 [Homo
sapiens]
Length = 929
Score = 51.6 bits (122), Expect = 2e-06
Identities = 47/191 (24%), Positives = 90/191 (47%), Gaps = 30/191 (15%)
Query: 107 DALKEKGNEAFAEGNYETAILRYSEGL---EKLKDMKVLYTNRAQAYMKLEDYEKALVDC 163
+ L+++GNE F G+Y A+ Y++ L +D VL+ NRA ++KLEDY+KA +
Sbjct: 7 EQLRKEGNELFKCGDYGGALAAYTQALGLDATPQDQAVLHRNRAACHLKLEDYDKAETEA 66
Query: 164 EWALKCDEKCTKAYFH-------MGKANLALKNYS--VSRECYKKILE-----INPKLQT 209
A++ D KA + +G+ + A+ + VS E K+ + I ++Q
Sbjct: 67 SKAIEKDGGDVKALYRRSQALEKLGRLDQAVLDLQRCVSLEPKNKVFQEALRNIGGQIQE 126
Query: 210 QVKGYLNQVD------LQEKADLQEKEAHELLDSGKNTAVTTKNLLETLSKPDQIPLFYA 263
+V+ Y++ D Q D +EK + + +N V + +F +
Sbjct: 127 KVR-YMSSTDAKVEQMFQILLDPEEKGTEKKQKASQNLVVLAR------EDAGAEKIFRS 179
Query: 264 GGIEILTEMIN 274
G+++L +++
Sbjct: 180 NGVQLLQRLLD 190
>gi|29725607 smooth muscle cell associated protein-1 isoform 2 [Homo
sapiens]
Length = 944
Score = 51.6 bits (122), Expect = 2e-06
Identities = 47/191 (24%), Positives = 90/191 (47%), Gaps = 30/191 (15%)
Query: 107 DALKEKGNEAFAEGNYETAILRYSEGL---EKLKDMKVLYTNRAQAYMKLEDYEKALVDC 163
+ L+++GNE F G+Y A+ Y++ L +D VL+ NRA ++KLEDY+KA +
Sbjct: 22 EQLRKEGNELFKCGDYGGALAAYTQALGLDATPQDQAVLHRNRAACHLKLEDYDKAETEA 81
Query: 164 EWALKCDEKCTKAYFH-------MGKANLALKNYS--VSRECYKKILE-----INPKLQT 209
A++ D KA + +G+ + A+ + VS E K+ + I ++Q
Sbjct: 82 SKAIEKDGGDVKALYRRSQALEKLGRLDQAVLDLQRCVSLEPKNKVFQEALRNIGGQIQE 141
Query: 210 QVKGYLNQVD------LQEKADLQEKEAHELLDSGKNTAVTTKNLLETLSKPDQIPLFYA 263
+V+ Y++ D Q D +EK + + +N V + +F +
Sbjct: 142 KVR-YMSSTDAKVEQMFQILLDPEEKGTEKKQKASQNLVVLAR------EDAGAEKIFRS 194
Query: 264 GGIEILTEMIN 274
G+++L +++
Sbjct: 195 NGVQLLQRLLD 205
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.317 0.131 0.364
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 23,236,679
Number of Sequences: 37866
Number of extensions: 939504
Number of successful extensions: 3925
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 73
Number of HSP's successfully gapped in prelim test: 132
Number of HSP's that attempted gapping in prelim test: 3582
Number of HSP's gapped (non-prelim): 402
length of query: 705
length of database: 18,247,518
effective HSP length: 109
effective length of query: 596
effective length of database: 14,120,124
effective search space: 8415593904
effective search space used: 8415593904
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.