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Search of human proteins with 90669511
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|90669511 crystallin, zeta-like 1 [Homo sapiens]
(349 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|90669511 crystallin, zeta-like 1 [Homo sapiens] 700 0.0
gi|194239674 crystallin, zeta isoform a [Homo sapiens] 69 6e-12
gi|13236495 crystallin, zeta isoform a [Homo sapiens] 69 6e-12
gi|47519420 reticulon 4 interacting protein 1 precursor [Homo sa... 66 5e-11
gi|194239676 crystallin, zeta isoform b [Homo sapiens] 65 7e-11
gi|22538446 tumor protein p53 inducible protein 3 [Homo sapiens] 60 2e-09
gi|22538444 tumor protein p53 inducible protein 3 [Homo sapiens] 60 2e-09
gi|24308257 vesicle amine transport protein 1 homolog (T. califo... 54 2e-07
gi|41872631 fatty acid synthase [Homo sapiens] 52 6e-07
gi|18379349 vesicle amine transport protein 1 [Homo sapiens] 48 1e-05
gi|28557745 zinc binding alcohol dehydrogenase domain containing... 37 0.034
gi|4501933 class I alcohol dehydrogenase, gamma subunit [Homo sa... 37 0.034
gi|34577061 class I alcohol dehydrogenase, beta subunit [Homo sa... 35 0.100
gi|226059159 prostaglandin reductase 1 isoform 1 [Homo sapiens] 35 0.13
gi|226059133 prostaglandin reductase 1 isoform 1 [Homo sapiens] 35 0.13
gi|226056130 prostaglandin reductase 1 isoform 2 [Homo sapiens] 35 0.13
gi|4501929 class I alcohol dehydrogenase, alpha subunit [Homo sa... 33 0.38
gi|67078406 trans-2-enoyl-CoA reductase, mitochondrial isoform b... 33 0.38
gi|67078404 trans-2-enoyl-CoA reductase, mitochondrial isoform a... 33 0.38
gi|71565154 class III alcohol dehydrogenase, chi subunit [Homo s... 32 0.85
gi|71743840 class IV alcohol dehydrogenase, mu or sigma subunit ... 32 1.1
gi|197927207 crystallin, zeta isoform c [Homo sapiens] 32 1.1
gi|66933014 3-hydroxybutyrate dehydrogenase, type 2 [Homo sapiens] 31 1.9
gi|71565152 class II alcohol dehydrogenase, pi subunit [Homo sap... 30 2.5
gi|189491771 thyroid hormone receptor, beta [Homo sapiens] 30 3.2
gi|189491769 thyroid hormone receptor, beta [Homo sapiens] 30 3.2
gi|40806162 thyroid hormone receptor, beta [Homo sapiens] 30 3.2
gi|4758648 kinesin family member 5B [Homo sapiens] 30 3.2
gi|221316741 N-acetyltransferase 10 isoform b [Homo sapiens] 30 3.2
gi|221316723 N-acetyltransferase 10 isoform a [Homo sapiens] 30 3.2
>gi|90669511 crystallin, zeta-like 1 [Homo sapiens]
Length = 349
Score = 700 bits (1806), Expect = 0.0
Identities = 349/349 (100%), Positives = 349/349 (100%)
Query: 1 MKGLYFQQSSTDEEITFVFQEKEDLPVTEDNFVKLQVKACALSQINTKLLAEMKMKKDLF 60
MKGLYFQQSSTDEEITFVFQEKEDLPVTEDNFVKLQVKACALSQINTKLLAEMKMKKDLF
Sbjct: 1 MKGLYFQQSSTDEEITFVFQEKEDLPVTEDNFVKLQVKACALSQINTKLLAEMKMKKDLF 60
Query: 61 PVGREIAGIVLDVGSKVSFFQPDDEVVGILPLDSEDPGLCEVVRVHEHYLVHKPEKVTWT 120
PVGREIAGIVLDVGSKVSFFQPDDEVVGILPLDSEDPGLCEVVRVHEHYLVHKPEKVTWT
Sbjct: 61 PVGREIAGIVLDVGSKVSFFQPDDEVVGILPLDSEDPGLCEVVRVHEHYLVHKPEKVTWT 120
Query: 121 EAAGSIRDGVRAYTALHYLSHLSPGKSVLIMDGASAFGTIAIQLAHHRGAKVISTACSLE 180
EAAGSIRDGVRAYTALHYLSHLSPGKSVLIMDGASAFGTIAIQLAHHRGAKVISTACSLE
Sbjct: 121 EAAGSIRDGVRAYTALHYLSHLSPGKSVLIMDGASAFGTIAIQLAHHRGAKVISTACSLE 180
Query: 181 DKQCLERFRPPIARVIDVSNGKVHVAESCLEETGGLGVDIVLDAGVRLYSKDDEPAVKLQ 240
DKQCLERFRPPIARVIDVSNGKVHVAESCLEETGGLGVDIVLDAGVRLYSKDDEPAVKLQ
Sbjct: 181 DKQCLERFRPPIARVIDVSNGKVHVAESCLEETGGLGVDIVLDAGVRLYSKDDEPAVKLQ 240
Query: 241 LLPHKHDIITLLGVGGHWVTTEENLQLDPPDSHCLFLKGATLAFLNDEVWNLSNVQQGKY 300
LLPHKHDIITLLGVGGHWVTTEENLQLDPPDSHCLFLKGATLAFLNDEVWNLSNVQQGKY
Sbjct: 241 LLPHKHDIITLLGVGGHWVTTEENLQLDPPDSHCLFLKGATLAFLNDEVWNLSNVQQGKY 300
Query: 301 LCILKDVMEKLSTGVFRPQLDEPIPLYEAKVSMEAVQKNQGRKKQVVQF 349
LCILKDVMEKLSTGVFRPQLDEPIPLYEAKVSMEAVQKNQGRKKQVVQF
Sbjct: 301 LCILKDVMEKLSTGVFRPQLDEPIPLYEAKVSMEAVQKNQGRKKQVVQF 349
>gi|194239674 crystallin, zeta isoform a [Homo sapiens]
Length = 329
Score = 68.9 bits (167), Expect = 6e-12
Identities = 61/232 (26%), Positives = 108/232 (46%), Gaps = 20/232 (8%)
Query: 25 LPVTEDNFVKLQVKACALSQINTKLLAEMKMKKDLFPV--GREIAGIVLDVGSKVSFFQP 82
+P+ +D+ V ++V AC ++ + T + + +K L P G ++AG++ VG S F+
Sbjct: 30 VPIPKDHQVLIKVHACGVNPVETYIRSGTYSRKPLLPYTPGSDVAGVIEAVGDNASAFKK 89
Query: 83 DDEVVGILPLDSEDPGLCEVVRVHEHYLVHKPEKVTWTEAAGSIRDGVRAYTALHYLSHL 142
D V + G E +H + PEK+ + + A AY AL + + +
Sbjct: 90 GDRVFTSSTISG---GYAEYALAADHTVYKLPEKLDFKQGAAIGIPYFTAYRALIHSACV 146
Query: 143 SPGKSVLIMDGASAFGTIAIQLAHHRGAKVISTACSLE-DKQCLERFRPPIARVIDVSNG 201
G+SVL+ + G A Q+A G K++ TA + E K L+ + ++
Sbjct: 147 KAGESVLVHGASGGVGLAACQIARAYGLKILGTAGTEEGQKIVLQNGAHEV-----FNHR 201
Query: 202 KVHVAESCLEETGGLGVDIVLD--AGVRLYSKDDEPAVKLQLLPHKHDIITL 251
+V+ + + G G+DI+++ A V L SKD L LL H +I +
Sbjct: 202 EVNYIDKIKKYVGEKGIDIIIEMLANVNL-SKD------LSLLSHGGRVIVV 246
>gi|13236495 crystallin, zeta isoform a [Homo sapiens]
Length = 329
Score = 68.9 bits (167), Expect = 6e-12
Identities = 61/232 (26%), Positives = 108/232 (46%), Gaps = 20/232 (8%)
Query: 25 LPVTEDNFVKLQVKACALSQINTKLLAEMKMKKDLFPV--GREIAGIVLDVGSKVSFFQP 82
+P+ +D+ V ++V AC ++ + T + + +K L P G ++AG++ VG S F+
Sbjct: 30 VPIPKDHQVLIKVHACGVNPVETYIRSGTYSRKPLLPYTPGSDVAGVIEAVGDNASAFKK 89
Query: 83 DDEVVGILPLDSEDPGLCEVVRVHEHYLVHKPEKVTWTEAAGSIRDGVRAYTALHYLSHL 142
D V + G E +H + PEK+ + + A AY AL + + +
Sbjct: 90 GDRVFTSSTISG---GYAEYALAADHTVYKLPEKLDFKQGAAIGIPYFTAYRALIHSACV 146
Query: 143 SPGKSVLIMDGASAFGTIAIQLAHHRGAKVISTACSLE-DKQCLERFRPPIARVIDVSNG 201
G+SVL+ + G A Q+A G K++ TA + E K L+ + ++
Sbjct: 147 KAGESVLVHGASGGVGLAACQIARAYGLKILGTAGTEEGQKIVLQNGAHEV-----FNHR 201
Query: 202 KVHVAESCLEETGGLGVDIVLD--AGVRLYSKDDEPAVKLQLLPHKHDIITL 251
+V+ + + G G+DI+++ A V L SKD L LL H +I +
Sbjct: 202 EVNYIDKIKKYVGEKGIDIIIEMLANVNL-SKD------LSLLSHGGRVIVV 246
>gi|47519420 reticulon 4 interacting protein 1 precursor [Homo
sapiens]
Length = 396
Score = 65.9 bits (159), Expect = 5e-11
Identities = 49/157 (31%), Positives = 84/157 (53%), Gaps = 10/157 (6%)
Query: 53 MKMKKDLFPV--GREIAGIVLDVGSKVSFFQPDDEVVGILPLDSEDPGLCEVVRVHEHYL 110
+K+K + FP+ GR+++G+V++ G V +F+P DEV +P + L E V V + +
Sbjct: 108 VKIKGEEFPLTLGRDVSGVVMECGLDVKYFKPGDEVWAAVP-PWKQGTLSEFVVVSGNEV 166
Query: 111 VHKPEKVTWTEAAGSIRDGVRAYTALHYLSHLS----PGKSVLIMDGASAFGTIAIQLAH 166
HKP+ +T T+AA + A++A++ + L+ GK VLI+ + GT AIQ+
Sbjct: 167 SHKPKSLTHTQAASLPYVALTAWSAINKVGGLNDKNCTGKRVLILGASGGVGTFAIQVMK 226
Query: 167 HRGAKVISTACSLEDKQCLERFRPPIARVIDVSNGKV 203
A V + CS + + + + VID +G V
Sbjct: 227 AWDAHV-TAVCSQDASELVRKLGAD--DVIDYKSGSV 260
>gi|194239676 crystallin, zeta isoform b [Homo sapiens]
Length = 295
Score = 65.5 bits (158), Expect = 7e-11
Identities = 43/161 (26%), Positives = 78/161 (48%), Gaps = 5/161 (3%)
Query: 25 LPVTEDNFVKLQVKACALSQINTKLLAEMKMKKDLFPV--GREIAGIVLDVGSKVSFFQP 82
+P+ +D+ V ++V AC ++ + T + + +K L P G ++AG++ VG S F+
Sbjct: 30 VPIPKDHQVLIKVHACGVNPVETYIRSGTYSRKPLLPYTPGSDVAGVIEAVGDNASAFKK 89
Query: 83 DDEVVGILPLDSEDPGLCEVVRVHEHYLVHKPEKVTWTEAAGSIRDGVRAYTALHYLSHL 142
D V + G E +H + PEK+ + + A AY AL + + +
Sbjct: 90 GDRVFTSSTISG---GYAEYALAADHTVYKLPEKLDFKQGAAIGIPYFTAYRALIHSACV 146
Query: 143 SPGKSVLIMDGASAFGTIAIQLAHHRGAKVISTACSLEDKQ 183
G+SVL+ + G A Q+A G K++ TA + E ++
Sbjct: 147 KAGESVLVHGASGGVGLAACQIARAYGLKILGTAGTEEGQK 187
>gi|22538446 tumor protein p53 inducible protein 3 [Homo sapiens]
Length = 332
Score = 60.5 bits (145), Expect = 2e-09
Identities = 60/204 (29%), Positives = 96/204 (47%), Gaps = 17/204 (8%)
Query: 26 PVTEDNFVKLQVKACALSQINTKLLAEMKMKKDLFP-----VGREIAGIVLDVGSKVS-F 79
P + V L+V A AL++ + L + + + D P +G E +G V ++G
Sbjct: 23 PSPGEGEVLLKVAASALNRAD---LMQRQGQYDPPPGASNILGLEASGHVAELGPGCQGH 79
Query: 80 FQPDDEVVGILPLDSEDPGLCEVVRVHEHYLVHKPEKVTWTEAAGSIRDGVRAYTALHYL 139
++ D + +LP G + V V E L+ PE +T T+AA + A+ LH +
Sbjct: 80 WKIGDTAMALLP----GGGQAQYVTVPEGLLMPIPEGLTLTQAAAIPEAWLTAFQLLHLV 135
Query: 140 SHLSPGKSVLIMDGASAFGTIAIQLAHHRGAKVISTACSLEDKQCLERFRPPIARVIDVS 199
++ G VLI G S GT AIQL GA + TA S + Q E+ + +
Sbjct: 136 GNVQAGDYVLIHAGLSGVGTAAIQLTRMAGAIPLVTAGSQKKLQMAEK----LGAAAGFN 191
Query: 200 NGKVHVAESCLEETGGLGVDIVLD 223
K +E+ L+ T G GV+++LD
Sbjct: 192 YKKEDFSEATLKFTKGAGVNLILD 215
>gi|22538444 tumor protein p53 inducible protein 3 [Homo sapiens]
Length = 332
Score = 60.5 bits (145), Expect = 2e-09
Identities = 60/204 (29%), Positives = 96/204 (47%), Gaps = 17/204 (8%)
Query: 26 PVTEDNFVKLQVKACALSQINTKLLAEMKMKKDLFP-----VGREIAGIVLDVGSKVS-F 79
P + V L+V A AL++ + L + + + D P +G E +G V ++G
Sbjct: 23 PSPGEGEVLLKVAASALNRAD---LMQRQGQYDPPPGASNILGLEASGHVAELGPGCQGH 79
Query: 80 FQPDDEVVGILPLDSEDPGLCEVVRVHEHYLVHKPEKVTWTEAAGSIRDGVRAYTALHYL 139
++ D + +LP G + V V E L+ PE +T T+AA + A+ LH +
Sbjct: 80 WKIGDTAMALLP----GGGQAQYVTVPEGLLMPIPEGLTLTQAAAIPEAWLTAFQLLHLV 135
Query: 140 SHLSPGKSVLIMDGASAFGTIAIQLAHHRGAKVISTACSLEDKQCLERFRPPIARVIDVS 199
++ G VLI G S GT AIQL GA + TA S + Q E+ + +
Sbjct: 136 GNVQAGDYVLIHAGLSGVGTAAIQLTRMAGAIPLVTAGSQKKLQMAEK----LGAAAGFN 191
Query: 200 NGKVHVAESCLEETGGLGVDIVLD 223
K +E+ L+ T G GV+++LD
Sbjct: 192 YKKEDFSEATLKFTKGAGVNLILD 215
>gi|24308257 vesicle amine transport protein 1 homolog (T.
californica)-like [Homo sapiens]
Length = 419
Score = 54.3 bits (129), Expect = 2e-07
Identities = 54/206 (26%), Positives = 92/206 (44%), Gaps = 17/206 (8%)
Query: 22 KEDLPVTEDNFVKLQVKACALSQINTKLLA---EMKMKKDLFPVGREIAGIVLDVGSKVS 78
++ +P +D +K++VKAC L+ I+ + + K L P G E +GIV +G V
Sbjct: 60 RKAMPEPQDGELKIRVKACGLNFIDLMVRQGNIDNPPKTPLVP-GFECSGIVEALGDSVK 118
Query: 79 FFQPDDEVVGILPLDSEDPGLCEVVRVHEHYLVHKPEKVTWTEAAGSIRDGVRAYTALHY 138
++ D V+ + ++ EVV ++ P+ ++++EAA + V AY L
Sbjct: 119 GYEIGDRVMAFVNYNA----WAEVVCTPVEFVYKIPDDMSFSEAAAFPMNFVTAYVMLFE 174
Query: 139 LSHLSPGKSVLIMDGASAFGTIAIQLAHH-RGAKVISTACSLEDKQCLERFRPPIARVID 197
+++L G SVL+ G QL V TA + + E + + + D
Sbjct: 175 VANLREGMSVLVHSAGGGVGQAVAQLCSTVPNVTVFGTASTFKH----EAIKDSVTHLFD 230
Query: 198 VSNGKVHVAESCLEETGGLGVDIVLD 223
+ V + E GVDIVLD
Sbjct: 231 RNADYVQEVKRISAE----GVDIVLD 252
>gi|41872631 fatty acid synthase [Homo sapiens]
Length = 2511
Score = 52.4 bits (124), Expect = 6e-07
Identities = 41/139 (29%), Positives = 63/139 (45%), Gaps = 4/139 (2%)
Query: 86 VVGILPLDSEDPGLCEVVRVHEHYLVHKPEKVTWTEAAGSIRDGVRAYTALHYLSHLSPG 145
V+G++P GL V + +L P T EAA AY AL + PG
Sbjct: 1613 VMGLVPAK----GLATSVLLSPDFLWDVPSNWTLEEAASVPVVYSTAYYALVVRGRVRPG 1668
Query: 146 KSVLIMDGASAFGTIAIQLAHHRGAKVISTACSLEDKQCLERFRPPIARVIDVSNGKVHV 205
+++LI G+ G AI +A G +V +T S E + L+ P + ++
Sbjct: 1669 ETLLIHSGSGGVGQAAIAIALSLGCRVFTTVGSAEKRAYLQARFPQLDSTSFANSRDTSF 1728
Query: 206 AESCLEETGGLGVDIVLDA 224
+ L TGG GVD+VL++
Sbjct: 1729 EQHVLWHTGGKGVDLVLNS 1747
>gi|18379349 vesicle amine transport protein 1 [Homo sapiens]
Length = 393
Score = 47.8 bits (112), Expect = 1e-05
Identities = 56/194 (28%), Positives = 87/194 (44%), Gaps = 17/194 (8%)
Query: 35 LQVKACALSQINTKLLAEMKMKKDLFPV----GREIAGIVLDVGSKVSFFQPDDEVVGIL 90
L+++AC L+ + L+A + L P+ G E AG+V+ VG VS + D V+ +
Sbjct: 81 LRLRACGLNFAD--LMARQGLYDRLPPLPVTPGMEGAGVVIAVGEGVSDRKAGDRVMVL- 137
Query: 91 PLDSEDPGLCEVVRVHEHYLVHKPEKVTWTEAAGSIRDGVRAYTALHYLSHLSPGKSVLI 150
+ E V V PE +T+ EAA + + + AY L +L PG SVL+
Sbjct: 138 ---NRSGMWQEEVTVPSVQTFLIPEAMTFEEAAALLVNYITAYMVLFDFGNLQPGHSVLV 194
Query: 151 MDGASAFGTIAIQLAHH-RGAKVISTACSLEDKQCLERFRPPIARVIDVSNGKVHVAESC 209
A G A+QL V TA + + + E + ID +V E
Sbjct: 195 HMAAGGVGMAAVQLCRTVENVTVFGTASASKHEALKEN---GVTHPIDYHTTD-YVDE-- 248
Query: 210 LEETGGLGVDIVLD 223
+++ GVDIV+D
Sbjct: 249 IKKISPKGVDIVMD 262
>gi|28557745 zinc binding alcohol dehydrogenase domain containing 2
[Homo sapiens]
Length = 377
Score = 36.6 bits (83), Expect = 0.034
Identities = 26/70 (37%), Positives = 34/70 (48%), Gaps = 7/70 (10%)
Query: 113 KPEKVTWTEAAGSIRDGVRAYTALHYLSHLSPGKSVLIMDGASAFGTIAIQLAHHRGAKV 172
KPE +T + G AY +L L LS GK VL+ A G A+QL+ V
Sbjct: 147 KPEYLTL------LVSGTTAYISLKELGGLSEGKKVLVTAAAGGTGQFAMQLSKKAKCHV 200
Query: 173 ISTACSLEDK 182
I T CS ++K
Sbjct: 201 IGT-CSSDEK 209
>gi|4501933 class I alcohol dehydrogenase, gamma subunit [Homo
sapiens]
Length = 375
Score = 36.6 bits (83), Expect = 0.034
Identities = 43/162 (26%), Positives = 68/162 (41%), Gaps = 18/162 (11%)
Query: 62 VGREIAGIVLDVGSKVSFFQPDDEVVGILPLDSEDPGLCEVVRVHEHYLVHKPEKVTWTE 121
+G E AGIV VG V+ +P D+V+ PL + G C + + E K +
Sbjct: 66 LGHEAAGIVESVGEGVTTVKPGDKVI---PLFTPQCGKCRICKNPESNYCLKND---LGN 119
Query: 122 AAGSIRDGVRAYTALHYLSHLSPGKSVLIMDGASAFGTIAIQLAHHRGAKVISTACSLED 181
G+++DG R +T GK + G S F + + + AK+ A S +
Sbjct: 120 PRGTLQDGTRRFTC--------SGKPIHHFVGVSTFSQYTV-VDENAVAKI--DAASPLE 168
Query: 182 KQCLERFRPPIARVIDVSNGKVHVAESC-LEETGGLGVDIVL 222
K CL V KV +C + GG+G+ +V+
Sbjct: 169 KVCLIGCGFSTGYGSAVKVAKVTPGSTCAVFGLGGVGLSVVM 210
>gi|34577061 class I alcohol dehydrogenase, beta subunit [Homo
sapiens]
Length = 375
Score = 35.0 bits (79), Expect = 0.100
Identities = 44/162 (27%), Positives = 68/162 (41%), Gaps = 18/162 (11%)
Query: 62 VGREIAGIVLDVGSKVSFFQPDDEVVGILPLDSEDPGLCEVVRVHEHYLVHKPEKVTWTE 121
+G E AGIV VG V+ +P D+V+ PL + G C V + E K +
Sbjct: 66 LGHEAAGIVESVGEGVTTVKPGDKVI---PLFTPQCGKCRVCKNPESNYCLKND---LGN 119
Query: 122 AAGSIRDGVRAYTALHYLSHLSPGKSVLIMDGASAFGTIAIQLAHHRGAKVISTACSLED 181
G+++DG R +T GK + G S F + + + AK+ A S +
Sbjct: 120 PRGTLQDGTRRFTC--------RGKPIHHFLGTSTFSQYTV-VDENAVAKI--DAASPLE 168
Query: 182 KQCLERFRPPIARVIDVSNGKVHVAESC-LEETGGLGVDIVL 222
K CL V+ KV +C + GG+G+ V+
Sbjct: 169 KVCLIGCGFSTGYGSAVNVAKVTPGSTCAVFGLGGVGLSAVM 210
>gi|226059159 prostaglandin reductase 1 isoform 1 [Homo sapiens]
Length = 329
Score = 34.7 bits (78), Expect = 0.13
Identities = 22/82 (26%), Positives = 41/82 (50%), Gaps = 1/82 (1%)
Query: 107 EHYLVHKPEKVTWTEAAGSI-RDGVRAYTALHYLSHLSPGKSVLIMDGASAFGTIAIQLA 165
E L P+ + + A G++ G+ AY L + + G++V++ A A G++ Q+A
Sbjct: 103 EKLLTEWPDTIPLSLALGTVGMPGLTAYFGLLEICGVKGGETVMVNAAAGAVGSVVGQIA 162
Query: 166 HHRGAKVISTACSLEDKQCLER 187
+G KV+ S E L++
Sbjct: 163 KLKGCKVVGAVGSDEKVAYLQK 184
>gi|226059133 prostaglandin reductase 1 isoform 1 [Homo sapiens]
Length = 329
Score = 34.7 bits (78), Expect = 0.13
Identities = 22/82 (26%), Positives = 41/82 (50%), Gaps = 1/82 (1%)
Query: 107 EHYLVHKPEKVTWTEAAGSI-RDGVRAYTALHYLSHLSPGKSVLIMDGASAFGTIAIQLA 165
E L P+ + + A G++ G+ AY L + + G++V++ A A G++ Q+A
Sbjct: 103 EKLLTEWPDTIPLSLALGTVGMPGLTAYFGLLEICGVKGGETVMVNAAAGAVGSVVGQIA 162
Query: 166 HHRGAKVISTACSLEDKQCLER 187
+G KV+ S E L++
Sbjct: 163 KLKGCKVVGAVGSDEKVAYLQK 184
>gi|226056130 prostaglandin reductase 1 isoform 2 [Homo sapiens]
Length = 301
Score = 34.7 bits (78), Expect = 0.13
Identities = 22/82 (26%), Positives = 41/82 (50%), Gaps = 1/82 (1%)
Query: 107 EHYLVHKPEKVTWTEAAGSI-RDGVRAYTALHYLSHLSPGKSVLIMDGASAFGTIAIQLA 165
E L P+ + + A G++ G+ AY L + + G++V++ A A G++ Q+A
Sbjct: 103 EKLLTEWPDTIPLSLALGTVGMPGLTAYFGLLEICGVKGGETVMVNAAAGAVGSVVGQIA 162
Query: 166 HHRGAKVISTACSLEDKQCLER 187
+G KV+ S E L++
Sbjct: 163 KLKGCKVVGAVGSDEKVAYLQK 184
>gi|4501929 class I alcohol dehydrogenase, alpha subunit [Homo
sapiens]
Length = 375
Score = 33.1 bits (74), Expect = 0.38
Identities = 25/95 (26%), Positives = 43/95 (45%), Gaps = 10/95 (10%)
Query: 62 VGREIAGIVLDVGSKVSFFQPDDEVVGILPLDSEDPGLCEVVRVHEHYLVHKPEKVTWTE 121
+G E AGIV VG V+ +P D+V+ PL G C + + E K + +
Sbjct: 66 LGHEAAGIVESVGEGVTTVKPGDKVI---PLAIPQCGKCRICKNPESNYCLKNDV---SN 119
Query: 122 AAGSIRDGVRAYTA----LHYLSHLSPGKSVLIMD 152
G+++DG +T +H+ +S ++D
Sbjct: 120 PQGTLQDGTSRFTCRRKPIHHFLGISTFSQYTVVD 154
>gi|67078406 trans-2-enoyl-CoA reductase, mitochondrial isoform b
[Homo sapiens]
Length = 297
Score = 33.1 bits (74), Expect = 0.38
Identities = 34/123 (27%), Positives = 47/123 (38%), Gaps = 3/123 (2%)
Query: 63 GREIAGIVLDVGSKVSFFQPDDEVVGILPLDSEDPGLCEVVRVHEHYLVHKPEKVTWTEA 122
G E V+ VGS V+ +P D V+ P ++ E L+ P + A
Sbjct: 29 GNEGVAQVVAVGSNVTGLKPGDWVI---PANAGLGTWRTEAVFSEEALIQVPSDIPLQSA 85
Query: 123 AGSIRDGVRAYTALHYLSHLSPGKSVLIMDGASAFGTIAIQLAHHRGAKVISTACSLEDK 182
A + AY L L PG SV+ S G IQ+A G + I+ D
Sbjct: 86 ATLGVNPCTAYRMLMDFEQLQPGDSVIQNASNSGVGQAVIQIAAALGLRTINVVRDRPDI 145
Query: 183 QCL 185
Q L
Sbjct: 146 QKL 148
>gi|67078404 trans-2-enoyl-CoA reductase, mitochondrial isoform a
[Homo sapiens]
Length = 373
Score = 33.1 bits (74), Expect = 0.38
Identities = 34/123 (27%), Positives = 47/123 (38%), Gaps = 3/123 (2%)
Query: 63 GREIAGIVLDVGSKVSFFQPDDEVVGILPLDSEDPGLCEVVRVHEHYLVHKPEKVTWTEA 122
G E V+ VGS V+ +P D V+ P ++ E L+ P + A
Sbjct: 105 GNEGVAQVVAVGSNVTGLKPGDWVI---PANAGLGTWRTEAVFSEEALIQVPSDIPLQSA 161
Query: 123 AGSIRDGVRAYTALHYLSHLSPGKSVLIMDGASAFGTIAIQLAHHRGAKVISTACSLEDK 182
A + AY L L PG SV+ S G IQ+A G + I+ D
Sbjct: 162 ATLGVNPCTAYRMLMDFEQLQPGDSVIQNASNSGVGQAVIQIAAALGLRTINVVRDRPDI 221
Query: 183 QCL 185
Q L
Sbjct: 222 QKL 224
>gi|71565154 class III alcohol dehydrogenase, chi subunit [Homo
sapiens]
Length = 374
Score = 32.0 bits (71), Expect = 0.85
Identities = 46/170 (27%), Positives = 69/170 (40%), Gaps = 20/170 (11%)
Query: 60 FPV--GREIAGIVLDVGSKVSFFQPDDEVVGILPLDSEDPGLCEVVRVHEHYLVHKPEKV 117
FPV G E AGIV VG V+ + D V+ PL G C+ + L +K+
Sbjct: 61 FPVILGHEGAGIVESVGEGVTKLKAGDTVI---PLYIPQCGECKFCLNPKTNLC---QKI 114
Query: 118 TWTEAAGSIRDGVRAYTALHYLSHLSPGKSVLIMDGASAFGTIAIQLAHHRGAKVISTAC 177
T+ G + DG +T GK++L G S F + +A AK+ A
Sbjct: 115 RVTQGKGLMPDGTSRFTC--------KGKTILHYMGTSTFSEYTV-VADISVAKIDPLAP 165
Query: 178 SLEDKQCLERFRPPIARVIDVSNGKVHVAESC-LEETGGLGVDIVLDAGV 226
DK CL V+ K+ C + GG+G+ +++ V
Sbjct: 166 L--DKVCLLGCGISTGYGAAVNTAKLEPGSVCAVFGLGGVGLAVIMGCKV 213
>gi|71743840 class IV alcohol dehydrogenase, mu or sigma subunit
[Homo sapiens]
Length = 386
Score = 31.6 bits (70), Expect = 1.1
Identities = 45/216 (20%), Positives = 85/216 (39%), Gaps = 28/216 (12%)
Query: 12 DEEITFVFQEKEDLPVTEDNFVKLQVKACALSQINTKLLAEMKMKKDLFPVGREIAGIVL 71
+++ F +E E P + V++++ A + + + ++ + K VG E GIV
Sbjct: 29 EQKQPFSIEEIEVAP-PKTKEVRIKILATGICRTDDHVIKGTMVSKFPVIVGHEATGIVE 87
Query: 72 DVGSKVSFFQPDDEVVGILPLDSEDPGLCEVVRVHEHYLVHKPEKVTWTEAAGSIRDGVR 131
+G V+ +P D+V+ PL C R + L + + G + DG
Sbjct: 88 SIGEGVTTVKPGDKVI---PLFLPQCRECNACRNPDGNLCIRSD----ITGRGVLADGTT 140
Query: 132 AYTA----LHYLSHLSPGKSVLIMDGASAFGTIAIQLAHHRGAKVISTACSLEDKQCLER 187
+T +H+ + S ++D +S AK+ A +K CL
Sbjct: 141 RFTCKGKPVHHFMNTSTFTEYTVVDESSV-------------AKIDDAA--PPEKVCLIG 185
Query: 188 FRPPIARVIDVSNGKVHVAESCLE-ETGGLGVDIVL 222
V GKV +C+ GG+G+ +++
Sbjct: 186 CGFSTGYGAAVKTGKVKPGSTCVVFGLGGVGLSVIM 221
>gi|197927207 crystallin, zeta isoform c [Homo sapiens]
Length = 192
Score = 31.6 bits (70), Expect = 1.1
Identities = 34/121 (28%), Positives = 57/121 (47%), Gaps = 17/121 (14%)
Query: 136 LHYLSH--LSPGKSVLIMDGASAFGTIAIQLAHHRGAKVISTACSLE-DKQCLERFRPPI 192
+H LS + G+SVL+ + G A Q+A G K++ TA + E K L+ +
Sbjct: 1 MHLLSSACVKAGESVLVHGASGGVGLAACQIARAYGLKILGTAGTEEGQKIVLQNGAHEV 60
Query: 193 ARVIDVSNGKVHVAESCLEETGGLGVDIVLD--AGVRLYSKDDEPAVKLQLLPHKHDIIT 250
++ +V+ + + G G+DI+++ A V L SKD L LL H +I
Sbjct: 61 -----FNHREVNYIDKIKKYVGEKGIDIIIEMLANVNL-SKD------LSLLSHGGRVIV 108
Query: 251 L 251
+
Sbjct: 109 V 109
>gi|66933014 3-hydroxybutyrate dehydrogenase, type 2 [Homo sapiens]
Length = 245
Score = 30.8 bits (68), Expect = 1.9
Identities = 19/58 (32%), Positives = 28/58 (48%)
Query: 145 GKSVLIMDGASAFGTIAIQLAHHRGAKVISTACSLEDKQCLERFRPPIARVIDVSNGK 202
GK +++ A G A GAKVI+T + Q LE++ RV+DV+ K
Sbjct: 6 GKVIILTAAAQGIGQAAALAFAREGAKVIATDINESKLQELEKYPGIQTRVLDVTKKK 63
>gi|71565152 class II alcohol dehydrogenase, pi subunit [Homo
sapiens]
Length = 380
Score = 30.4 bits (67), Expect = 2.5
Identities = 19/57 (33%), Positives = 33/57 (57%), Gaps = 3/57 (5%)
Query: 33 VKLQVKACALSQINTKLLAEMKMKKDLFPV--GREIAGIVLDVGSKVSFFQPDDEVV 87
V++Q+ A +L + ++ + K + FPV G E AGIV +G V+ +P D+V+
Sbjct: 37 VRIQIIATSLCHTDATVI-DSKFEGLAFPVIVGHEAAGIVESIGPGVTNVKPGDKVI 92
>gi|189491771 thyroid hormone receptor, beta [Homo sapiens]
Length = 461
Score = 30.0 bits (66), Expect = 3.2
Identities = 24/88 (27%), Positives = 39/88 (44%), Gaps = 17/88 (19%)
Query: 66 IAGIVLDVGSKVSFFQPDDEVVGILP----LDSEDPGLCEVVRVH----------EHYLV 111
++ + D+G +S F DD V +L + S+ PGL V R+ EHY+
Sbjct: 349 VSDAIFDLGMSLSSFNLDDTEVALLQAVLLMSSDRPGLACVERIEKYQDSFLLAFEHYIN 408
Query: 112 HKPEKVT--WTEAAGSIRDGVRAYTALH 137
++ VT W + + D +R A H
Sbjct: 409 YRKHHVTHFWPKLLMKVTD-LRMIGACH 435
>gi|189491769 thyroid hormone receptor, beta [Homo sapiens]
Length = 461
Score = 30.0 bits (66), Expect = 3.2
Identities = 24/88 (27%), Positives = 39/88 (44%), Gaps = 17/88 (19%)
Query: 66 IAGIVLDVGSKVSFFQPDDEVVGILP----LDSEDPGLCEVVRVH----------EHYLV 111
++ + D+G +S F DD V +L + S+ PGL V R+ EHY+
Sbjct: 349 VSDAIFDLGMSLSSFNLDDTEVALLQAVLLMSSDRPGLACVERIEKYQDSFLLAFEHYIN 408
Query: 112 HKPEKVT--WTEAAGSIRDGVRAYTALH 137
++ VT W + + D +R A H
Sbjct: 409 YRKHHVTHFWPKLLMKVTD-LRMIGACH 435
>gi|40806162 thyroid hormone receptor, beta [Homo sapiens]
Length = 461
Score = 30.0 bits (66), Expect = 3.2
Identities = 24/88 (27%), Positives = 39/88 (44%), Gaps = 17/88 (19%)
Query: 66 IAGIVLDVGSKVSFFQPDDEVVGILP----LDSEDPGLCEVVRVH----------EHYLV 111
++ + D+G +S F DD V +L + S+ PGL V R+ EHY+
Sbjct: 349 VSDAIFDLGMSLSSFNLDDTEVALLQAVLLMSSDRPGLACVERIEKYQDSFLLAFEHYIN 408
Query: 112 HKPEKVT--WTEAAGSIRDGVRAYTALH 137
++ VT W + + D +R A H
Sbjct: 409 YRKHHVTHFWPKLLMKVTD-LRMIGACH 435
>gi|4758648 kinesin family member 5B [Homo sapiens]
Length = 963
Score = 30.0 bits (66), Expect = 3.2
Identities = 32/123 (26%), Positives = 52/123 (42%), Gaps = 11/123 (8%)
Query: 182 KQCLERFRPPIARVIDVSNGKVHVAESCLEETGGLGV--DIVLDAGVRLYSKDD--EPAV 237
K LE + I S+GK H E L + G+G+ IV D +YS D+ E +
Sbjct: 71 KDVLEGYNGTIFAYGQTSSGKTHTMEGKLHDPEGMGIIPRIVQDIFNYIYSMDENLEFHI 130
Query: 238 KLQLLP-HKHDIITLLGVGGHWVTTEENLQLDPPDSHCLFLKGATLAFLNDEVWNLSNVQ 296
K+ + I LL V ++ NL + + ++KG T F+ + +
Sbjct: 131 KVSYFEIYLDKIRDLLDV------SKTNLSVHEDKNRVPYVKGCTERFVCSPDEVMDTID 184
Query: 297 QGK 299
+GK
Sbjct: 185 EGK 187
>gi|221316741 N-acetyltransferase 10 isoform b [Homo sapiens]
Length = 953
Score = 30.0 bits (66), Expect = 3.2
Identities = 28/123 (22%), Positives = 52/123 (42%), Gaps = 8/123 (6%)
Query: 126 IRDGVRAYTALHYLSHLSPGKSVLIMDGASAFGTIAIQLAHHRGAKVISTACSLEDKQCL 185
I D + A + +++L+ L L + A + + I L H+ + L Q +
Sbjct: 766 IMDMIPAISRIYFLNQLGD----LALSAAQSALLLGIGL-QHKSVDQLEKEIELPSGQLM 820
Query: 186 ERFRPPIARVIDVSNGKVHVAESCLEETGGLGVDIVLDAGVRLYSKDDEPAVKLQLLPHK 245
F I +V+ + N V E +EE D+V++ ++ S D + A K HK
Sbjct: 821 GLFNRIIRKVVKLFN---EVQEKAIEEQMVAAKDVVMEPTMKTLSDDLDEAAKEFQEKHK 877
Query: 246 HDI 248
++
Sbjct: 878 KEV 880
>gi|221316723 N-acetyltransferase 10 isoform a [Homo sapiens]
Length = 1025
Score = 30.0 bits (66), Expect = 3.2
Identities = 28/123 (22%), Positives = 52/123 (42%), Gaps = 8/123 (6%)
Query: 126 IRDGVRAYTALHYLSHLSPGKSVLIMDGASAFGTIAIQLAHHRGAKVISTACSLEDKQCL 185
I D + A + +++L+ L L + A + + I L H+ + L Q +
Sbjct: 838 IMDMIPAISRIYFLNQLGD----LALSAAQSALLLGIGL-QHKSVDQLEKEIELPSGQLM 892
Query: 186 ERFRPPIARVIDVSNGKVHVAESCLEETGGLGVDIVLDAGVRLYSKDDEPAVKLQLLPHK 245
F I +V+ + N V E +EE D+V++ ++ S D + A K HK
Sbjct: 893 GLFNRIIRKVVKLFN---EVQEKAIEEQMVAAKDVVMEPTMKTLSDDLDEAAKEFQEKHK 949
Query: 246 HDI 248
++
Sbjct: 950 KEV 952
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.319 0.137 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 13,718,214
Number of Sequences: 37866
Number of extensions: 621185
Number of successful extensions: 1288
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 18
Number of HSP's successfully gapped in prelim test: 24
Number of HSP's that attempted gapping in prelim test: 1262
Number of HSP's gapped (non-prelim): 42
length of query: 349
length of database: 18,247,518
effective HSP length: 103
effective length of query: 246
effective length of database: 14,347,320
effective search space: 3529440720
effective search space used: 3529440720
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.