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Search of human proteins with 89886453
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|89886453 TBC1 domain family, member 24 [Homo sapiens]
(553 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|89886453 TBC1 domain family, member 24 [Homo sapiens] 1132 0.0
gi|194306543 oxidation resistance 1 isoform 2 [Homo sapiens] 77 5e-14
gi|194306541 oxidation resistance 1 isoform 1 [Homo sapiens] 77 5e-14
gi|62909985 hypothetical protein LOC140711 [Homo sapiens] 76 7e-14
gi|170932526 nuclear receptor coactivator 7 isoform 2 [Homo sapi... 69 1e-11
gi|170932524 nuclear receptor coactivator 7 isoform 1 [Homo sapi... 69 1e-11
gi|194018478 TBC1 domain family, member 2B isoform a [Homo sapiens] 51 3e-06
gi|194018476 TBC1 domain family, member 2B isoform b [Homo sapiens] 50 4e-06
gi|13994322 TBC1 domain family, member 10A [Homo sapiens] 49 9e-06
gi|167614488 TBC1 domain family, member 10B [Homo sapiens] 47 5e-05
gi|139394668 TBC1 domain family, member 9 (with GRAM domain) [Ho... 47 6e-05
gi|21687020 ecotropic viral integration site 5-like isoform 2 [H... 44 3e-04
gi|205360930 hypothetical protein LOC57707 [Homo sapiens] 44 3e-04
gi|38348348 TBC1 domain family, member 10C [Homo sapiens] 44 4e-04
gi|114688046 TBC1 domain family, member 4 [Homo sapiens] 43 9e-04
gi|164519084 RAB GTPase activating protein 1 [Homo sapiens] 42 0.001
gi|68299759 ecotropic viral integration site 5 [Homo sapiens] 42 0.002
gi|148806902 TBC1 domain family, member 12 [Homo sapiens] 41 0.003
gi|229577000 ecotropic viral integration site 5-like isoform 1 [... 41 0.003
gi|29648315 small G protein signaling modulator 3 [Homo sapiens] 41 0.003
gi|164565381 TBC1 domain family, member 14 isoform b [Homo sapiens] 40 0.006
gi|164565368 TBC1 domain family, member 14 isoform a [Homo sapiens] 40 0.006
gi|164565366 TBC1 domain family, member 14 isoform a [Homo sapiens] 40 0.006
gi|156231067 TBC1 domain family, member 8 [Homo sapiens] 40 0.006
gi|50658061 TBC1 (tre-2/USP6, BUB2, cdc16) domain family, member... 39 0.012
gi|78217386 RAB GTPase activating protein 1-like isoform A [Homo... 39 0.012
gi|38570101 TBC1 domain family, member 8B (with GRAM domain) iso... 37 0.062
gi|118722351 growth hormone regulated TBC protein 1 [Homo sapiens] 37 0.062
gi|222352143 TBC1 domain family, member 2 [Homo sapiens] 32 1.2
gi|10092639 cysteine-rich motor neuron 1 [Homo sapiens] 32 2.0
>gi|89886453 TBC1 domain family, member 24 [Homo sapiens]
Length = 553
Score = 1132 bits (2927), Expect = 0.0
Identities = 553/553 (100%), Positives = 553/553 (100%)
Query: 1 MDSPGYNCFVDKDKMDAAIQDLGPKELSCTELQELKQLARQGYWAQSHALRGKVYQRLIR 60
MDSPGYNCFVDKDKMDAAIQDLGPKELSCTELQELKQLARQGYWAQSHALRGKVYQRLIR
Sbjct: 1 MDSPGYNCFVDKDKMDAAIQDLGPKELSCTELQELKQLARQGYWAQSHALRGKVYQRLIR 60
Query: 61 DIPCRTVTPDASVYSDIVGKIVGKHSSSCLPLPEFVDNTQVPSYCLNARGEGAVRKILLC 120
DIPCRTVTPDASVYSDIVGKIVGKHSSSCLPLPEFVDNTQVPSYCLNARGEGAVRKILLC
Sbjct: 61 DIPCRTVTPDASVYSDIVGKIVGKHSSSCLPLPEFVDNTQVPSYCLNARGEGAVRKILLC 120
Query: 121 LANQFPDISFCPALPAVVALLLHYSIDEAECFEKACRILACNDPGRRLIDQSFLAFESSC 180
LANQFPDISFCPALPAVVALLLHYSIDEAECFEKACRILACNDPGRRLIDQSFLAFESSC
Sbjct: 121 LANQFPDISFCPALPAVVALLLHYSIDEAECFEKACRILACNDPGRRLIDQSFLAFESSC 180
Query: 181 MTFGDLVNKYCQAAHKLMVAVSEDVLQVYADWQRWLFGELPLCYFARVFDVFLVEGYKVL 240
MTFGDLVNKYCQAAHKLMVAVSEDVLQVYADWQRWLFGELPLCYFARVFDVFLVEGYKVL
Sbjct: 181 MTFGDLVNKYCQAAHKLMVAVSEDVLQVYADWQRWLFGELPLCYFARVFDVFLVEGYKVL 240
Query: 241 YRVALAILKFFHKVRAGQPLESDSVKQDIRTFVRDIAKTVSPEKLLEKAFAIRLFSRKEI 300
YRVALAILKFFHKVRAGQPLESDSVKQDIRTFVRDIAKTVSPEKLLEKAFAIRLFSRKEI
Sbjct: 241 YRVALAILKFFHKVRAGQPLESDSVKQDIRTFVRDIAKTVSPEKLLEKAFAIRLFSRKEI 300
Query: 301 QLLQMANEKALKQKGITVKQKRQFVHLAVHAENFRSEIVSVREMRDIWSWVPERFALCQP 360
QLLQMANEKALKQKGITVKQKRQFVHLAVHAENFRSEIVSVREMRDIWSWVPERFALCQP
Sbjct: 301 QLLQMANEKALKQKGITVKQKRQFVHLAVHAENFRSEIVSVREMRDIWSWVPERFALCQP 360
Query: 361 LLLFSSLQHGYSLARFYFQCEGHEPTLLLIKTTQKEVCGAYLSTDWSERNKFGGKLGFFG 420
LLLFSSLQHGYSLARFYFQCEGHEPTLLLIKTTQKEVCGAYLSTDWSERNKFGGKLGFFG
Sbjct: 361 LLLFSSLQHGYSLARFYFQCEGHEPTLLLIKTTQKEVCGAYLSTDWSERNKFGGKLGFFG 420
Query: 421 TGECFVFRLQPEVQRYEWVVIKHPELTKPPPLMAAEPTAPLSHSASSDPADRLSPFLAAR 480
TGECFVFRLQPEVQRYEWVVIKHPELTKPPPLMAAEPTAPLSHSASSDPADRLSPFLAAR
Sbjct: 421 TGECFVFRLQPEVQRYEWVVIKHPELTKPPPLMAAEPTAPLSHSASSDPADRLSPFLAAR 480
Query: 481 HFNLPSKTESMFMAGGSDCLIVGGGGGQALYIDGDLNRGRTSHCDTFNNQPLCSENFLIA 540
HFNLPSKTESMFMAGGSDCLIVGGGGGQALYIDGDLNRGRTSHCDTFNNQPLCSENFLIA
Sbjct: 481 HFNLPSKTESMFMAGGSDCLIVGGGGGQALYIDGDLNRGRTSHCDTFNNQPLCSENFLIA 540
Query: 541 AVEAWGFQDPDTQ 553
AVEAWGFQDPDTQ
Sbjct: 541 AVEAWGFQDPDTQ 553
>gi|194306543 oxidation resistance 1 isoform 2 [Homo sapiens]
Length = 839
Score = 76.6 bits (187), Expect = 5e-14
Identities = 68/257 (26%), Positives = 108/257 (42%), Gaps = 67/257 (26%)
Query: 306 ANEKALKQKGITVKQKRQFVHLA-----VHAENFR------SEIVSVREMRDIWSWVPER 354
+N+ A ++ IT ++ +A + +E+FR SE++ ++ + +P R
Sbjct: 636 SNQAAAREWEITTREDINSKQVATVKADLESESFRPNLSDPSELLLPDQIEKLTKHLPPR 695
Query: 355 FALCQPLLLFSSLQHGYSLARFYFQCEGHE-PTLLLIKTTQKEVCGAYLSTDWSERNKFG 413
L++ + +HG SL Y G + P L++IK + +V GA S +
Sbjct: 696 TIGYPWTLVYGTGKHGTSLKTLYRTMTGLDTPVLMVIKDSDGQVFGALASEPLKVSD--- 752
Query: 414 GKLGFFGTGECFVFRLQPEVQRYEWVVIKHPELTKPPPLMAAEPTAPLSHSASSDPADRL 473
GF+GTGE FVF PE + ++W D +
Sbjct: 753 ---GFYGTGETFVFTFCPEFEVFKWT------------------------------GDNM 779
Query: 474 SPFLAARHFNLPSKTESMFMAGGSDCLIVGGGGGQ-ALYIDGDLNRGRTSHCDTFNNQPL 532
F+ G D L GGGGG+ AL++DGDL GR+ C TF N+ L
Sbjct: 780 -----------------FFIKGDMDSLAFGGGGGEFALWLDGDLYHGRSHSCKTFGNRTL 822
Query: 533 C-SENFLIAAVEAWGFQ 548
E+F I +E W F+
Sbjct: 823 SKKEDFFIQDIEIWAFE 839
>gi|194306541 oxidation resistance 1 isoform 1 [Homo sapiens]
Length = 846
Score = 76.6 bits (187), Expect = 5e-14
Identities = 68/257 (26%), Positives = 108/257 (42%), Gaps = 67/257 (26%)
Query: 306 ANEKALKQKGITVKQKRQFVHLA-----VHAENFR------SEIVSVREMRDIWSWVPER 354
+N+ A ++ IT ++ +A + +E+FR SE++ ++ + +P R
Sbjct: 643 SNQAAAREWEITTREDINSKQVATVKADLESESFRPNLSDPSELLLPDQIEKLTKHLPPR 702
Query: 355 FALCQPLLLFSSLQHGYSLARFYFQCEGHE-PTLLLIKTTQKEVCGAYLSTDWSERNKFG 413
L++ + +HG SL Y G + P L++IK + +V GA S +
Sbjct: 703 TIGYPWTLVYGTGKHGTSLKTLYRTMTGLDTPVLMVIKDSDGQVFGALASEPLKVSD--- 759
Query: 414 GKLGFFGTGECFVFRLQPEVQRYEWVVIKHPELTKPPPLMAAEPTAPLSHSASSDPADRL 473
GF+GTGE FVF PE + ++W D +
Sbjct: 760 ---GFYGTGETFVFTFCPEFEVFKWT------------------------------GDNM 786
Query: 474 SPFLAARHFNLPSKTESMFMAGGSDCLIVGGGGGQ-ALYIDGDLNRGRTSHCDTFNNQPL 532
F+ G D L GGGGG+ AL++DGDL GR+ C TF N+ L
Sbjct: 787 -----------------FFIKGDMDSLAFGGGGGEFALWLDGDLYHGRSHSCKTFGNRTL 829
Query: 533 C-SENFLIAAVEAWGFQ 548
E+F I +E W F+
Sbjct: 830 SKKEDFFIQDIEIWAFE 846
>gi|62909985 hypothetical protein LOC140711 [Homo sapiens]
Length = 215
Score = 76.3 bits (186), Expect = 7e-14
Identities = 58/213 (27%), Positives = 93/213 (43%), Gaps = 56/213 (26%)
Query: 336 SEIVSVREMRDIWSWVPERFALCQPLLLFSSLQHGYSLARFYFQCEGHE-PTLLLIKTTQ 394
S+++S E+R + P R L+F + + G+SL Y + EG P LL+++
Sbjct: 53 SQVLSASEIRQLSFHFPPRVTGHPWSLVFCTSRDGFSLQSLYRRMEGCSGPVLLVLRDQD 112
Query: 395 KEVCGAYLSTDWSERNKFGGKLGFFGTGECFVFRLQPEVQRYEWVVIKHPELTKPPPLMA 454
++ GA+ S+ GF+GTGE F+F P+++ ++W
Sbjct: 113 GQIFGAFSSS------AIRLSKGFYGTGETFLFSFSPQLKVFKW---------------- 150
Query: 455 AEPTAPLSHSASSDPADRLSPFLAARHFNLPSKTESMFMAGGSDCLIVGGGGGQ-ALYID 513
+ + S F+ G D L++G G G+ L++D
Sbjct: 151 -------------------------------TGSNSFFVKGDLDSLMMGSGSGRFGLWLD 179
Query: 514 GDLNRGRTSHCDTFNNQPLC-SENFLIAAVEAW 545
GDL RG +S C TFNN+ L E F I +EAW
Sbjct: 180 GDLFRGGSSPCPTFNNEVLARQEQFCIQELEAW 212
>gi|170932526 nuclear receptor coactivator 7 isoform 2 [Homo
sapiens]
Length = 931
Score = 68.9 bits (167), Expect = 1e-11
Identities = 52/189 (27%), Positives = 80/189 (42%), Gaps = 56/189 (29%)
Query: 362 LLFSSLQHGYSLARFYFQCEGHE-PTLLLIKTTQKEVCGAYLSTDWSERNKFGGKLGFFG 420
L +S+L+HG SL Y + + P LL+IK ++ GAY + + KF ++G
Sbjct: 795 LAYSTLEHGTSLKTLYRKSASLDSPVLLVIKDMDNQIFGAYATHPF----KFSDH--YYG 848
Query: 421 TGECFVFRLQPEVQRYEWVVIKHPELTKPPPLMAAEPTAPLSHSASSDPADRLSPFLAAR 480
TGE F++ P + ++W
Sbjct: 849 TGETFLYTFSPHFKVFKW------------------------------------------ 866
Query: 481 HFNLPSKTESMFMAGGSDCLIVGGGGGQ-ALYIDGDLNRGRTSHCDTFNNQPLC-SENFL 538
S S F+ G L +GGGGG+ L++D DL GR++ C TFNN L E+F+
Sbjct: 867 -----SGENSYFINGDISSLELGGGGGRFGLWLDADLYHGRSNSCSTFNNDILSKKEDFI 921
Query: 539 IAAVEAWGF 547
+ +E W F
Sbjct: 922 VQDLEVWAF 930
>gi|170932524 nuclear receptor coactivator 7 isoform 1 [Homo
sapiens]
Length = 942
Score = 68.9 bits (167), Expect = 1e-11
Identities = 52/189 (27%), Positives = 80/189 (42%), Gaps = 56/189 (29%)
Query: 362 LLFSSLQHGYSLARFYFQCEGHE-PTLLLIKTTQKEVCGAYLSTDWSERNKFGGKLGFFG 420
L +S+L+HG SL Y + + P LL+IK ++ GAY + + KF ++G
Sbjct: 806 LAYSTLEHGTSLKTLYRKSASLDSPVLLVIKDMDNQIFGAYATHPF----KFSDH--YYG 859
Query: 421 TGECFVFRLQPEVQRYEWVVIKHPELTKPPPLMAAEPTAPLSHSASSDPADRLSPFLAAR 480
TGE F++ P + ++W
Sbjct: 860 TGETFLYTFSPHFKVFKW------------------------------------------ 877
Query: 481 HFNLPSKTESMFMAGGSDCLIVGGGGGQ-ALYIDGDLNRGRTSHCDTFNNQPLC-SENFL 538
S S F+ G L +GGGGG+ L++D DL GR++ C TFNN L E+F+
Sbjct: 878 -----SGENSYFINGDISSLELGGGGGRFGLWLDADLYHGRSNSCSTFNNDILSKKEDFI 932
Query: 539 IAAVEAWGF 547
+ +E W F
Sbjct: 933 VQDLEVWAF 941
>gi|194018478 TBC1 domain family, member 2B isoform a [Homo sapiens]
Length = 963
Score = 50.8 bits (120), Expect = 3e-06
Identities = 66/272 (24%), Positives = 121/272 (44%), Gaps = 18/272 (6%)
Query: 25 KELSCTELQELKQLARQGYWAQSHALRGKVYQRLI-RDIPCRTVTPDASVYSDIVGKIVG 83
+E+ C+ ELK L R G H R KV++ + R + + ++ K +
Sbjct: 647 REMMCSP--ELKNLIRAGI---PHEHRSKVWKWCVDRHTRKFKDNTEPGHFQTLLQKALE 701
Query: 84 KHSSSC----LPLPEFVDNTQVPSYCLNARGEGAVRKILLCLANQFPDISFCPALPAVVA 139
K + + L L + N + S C + G +R +LL + + PDI +C L +VA
Sbjct: 702 KQNPASKQIELDLLRTLPNNKHYS-CPTSEGIQKLRNVLLAFSWRNPDIGYCQGLNRLVA 760
Query: 140 LLLHYSIDEAECFEKACRILACNDPGRRLIDQSFLAFESSCMTFGDLVNKYCQAAHKLMV 199
+ L Y +++ + F I+ P R ++ L + F DL+++ H
Sbjct: 761 VALLY-LEQEDAFWCLVTIVEVFMP-RDYYTKTLLGSQVDQRVFRDLMSEKLPRLHGHFE 818
Query: 200 AVSEDVLQVYADWQRWLFGELPLC-YFARVFDVFLVEGYKVLYRVALAILKFFHKVRAGQ 258
D + +W +F + + +++D FL EG KV++R ALA+ K + + +
Sbjct: 819 QYKVDYTLITFNWFLVVFVDSVVSDILFKIWDSFLYEGPKVIFRFALALFK-YKEEEILK 877
Query: 259 PLESDSVKQDIRTFVRDIAKTVSPEKLLEKAF 290
+S S+ + +R F R I + KL+ +F
Sbjct: 878 LQDSMSIFKYLRYFTRTI---LDARKLISISF 906
>gi|194018476 TBC1 domain family, member 2B isoform b [Homo sapiens]
Length = 914
Score = 50.4 bits (119), Expect = 4e-06
Identities = 63/258 (24%), Positives = 115/258 (44%), Gaps = 15/258 (5%)
Query: 25 KELSCTELQELKQLARQGYWAQSHALRGKVYQRLI-RDIPCRTVTPDASVYSDIVGKIVG 83
+E+ C+ ELK L R G H R KV++ + R + + ++ K +
Sbjct: 647 REMMCSP--ELKNLIRAGI---PHEHRSKVWKWCVDRHTRKFKDNTEPGHFQTLLQKALE 701
Query: 84 KHSSSC----LPLPEFVDNTQVPSYCLNARGEGAVRKILLCLANQFPDISFCPALPAVVA 139
K + + L L + N + S C + G +R +LL + + PDI +C L +VA
Sbjct: 702 KQNPASKQIELDLLRTLPNNKHYS-CPTSEGIQKLRNVLLAFSWRNPDIGYCQGLNRLVA 760
Query: 140 LLLHYSIDEAECFEKACRILACNDPGRRLIDQSFLAFESSCMTFGDLVNKYCQAAHKLMV 199
+ L Y +++ + F I+ P R ++ L + F DL+++ H
Sbjct: 761 VALLY-LEQEDAFWCLVTIVEVFMP-RDYYTKTLLGSQVDQRVFRDLMSEKLPRLHGHFE 818
Query: 200 AVSEDVLQVYADWQRWLFGELPLC-YFARVFDVFLVEGYKVLYRVALAILKFFHKVRAGQ 258
D + +W +F + + +++D FL EG KV++R ALA+ K + + +
Sbjct: 819 QYKVDYTLITFNWFLVVFVDSVVSDILFKIWDSFLYEGPKVIFRFALALFK-YKEEEILK 877
Query: 259 PLESDSVKQDIRTFVRDI 276
+S S+ + +R F R I
Sbjct: 878 LQDSMSIFKYLRYFTRTI 895
>gi|13994322 TBC1 domain family, member 10A [Homo sapiens]
Length = 508
Score = 49.3 bits (116), Expect = 9e-06
Identities = 45/186 (24%), Positives = 78/186 (41%), Gaps = 13/186 (6%)
Query: 110 GEGAVRKILLCLANQFPDISFCPA-LPAVVALLLHYSIDEAECFEKACRILACNDPGRRL 168
G+ + ++L P+ +C A P LL+H ++A C + C
Sbjct: 175 GQQDLFRVLKAYTLYRPEEGYCQAQAPIAAVLLMHMPAEQAFW----CLVQICEKYLPGY 230
Query: 169 IDQSFLAFESSCMTFGDLVNKYCQAAHKLMVAVSEDVLQVYADWQRWLFGE-LPLCYFAR 227
+ A + L+ K AHK + D L +W F LP R
Sbjct: 231 YSEKLEAIQLDGEILFSLLQKVSPVAHKHLSRQKIDPLLYMTEWFMCAFSRTLPWSSVLR 290
Query: 228 VFDVFLVEGYKVLYRVALAILKFFHKVRAGQPLESDSVKQDIRTFVRDIAKTVSPEKLLE 287
V+D+F EG K+++RV L +LK G P + + + T R +++SP K+++
Sbjct: 291 VWDMFFCEGVKIIFRVGLVLLKH----ALGSPEKVKACQGQYETIER--LRSLSP-KIMQ 343
Query: 288 KAFAIR 293
+AF ++
Sbjct: 344 EAFLVQ 349
>gi|167614488 TBC1 domain family, member 10B [Homo sapiens]
Length = 808
Score = 47.0 bits (110), Expect = 5e-05
Identities = 46/208 (22%), Positives = 88/208 (42%), Gaps = 15/208 (7%)
Query: 110 GEGAVRKILLCLANQFPDISFCPA-LPAVVALLLHYSIDEAECFEKACRILACNDPGRRL 168
G+ + +IL PD +C A P LL+H ++A C + C+
Sbjct: 424 GQQDLYRILKAYTIYRPDEGYCQAQAPVAAVLLMHMPAEQAFW----CLVQICDKYLPGY 479
Query: 169 IDQSFLAFESSCMTFGDLVNKYCQAAHKLMVAVSEDVLQVYADWQRWLFGE-LPLCYFAR 227
A + F L+ + AH+ + D + +W +F LP R
Sbjct: 480 YSAGLEAIQLDGEIFFALLRRASPLAHRHLRRQRIDPVLYMTEWFMCIFARTLPWASVLR 539
Query: 228 VFDVFLVEGYKVLYRVALAILKFFHKVRAGQPLESDSVKQDIRTFVRDIAKTVSPEKLLE 287
V+D+F EG K+++RVAL +L+ H + + + L S + +R++ P++ ++
Sbjct: 540 VWDMFFCEGVKIIFRVALVLLR--HTLGSVEKLRSCQGMYETMEQLRNL-----PQQCMQ 592
Query: 288 KAFAIRLFSRKEI--QLLQMANEKALKQ 313
+ F + + + L++ N LK+
Sbjct: 593 EDFLVHEVTNLPVTEALIERENAAQLKK 620
>gi|139394668 TBC1 domain family, member 9 (with GRAM domain) [Homo
sapiens]
Length = 1266
Score = 46.6 bits (109), Expect = 6e-05
Identities = 53/210 (25%), Positives = 95/210 (45%), Gaps = 24/210 (11%)
Query: 49 ALRGKVYQRLIRDIPCRTVTPDASVYSDIVGKIVGKHSSSCLPLPEFVDNT--QVPSYCL 106
++RG+++ L I + P Y D+V K +GK++ + + + + + P++
Sbjct: 519 SMRGELWLLLSGAINEKATHP--GYYEDLVEKSMGKYNLATEEIERDLHRSLPEHPAF-Q 575
Query: 107 NARGEGAVRKILLCLANQFPDISFCPALPAVVALLLHYSIDEAECF---EKACRILACND 163
N G A+R++L A + P+I +C A+ V ++LL Y+ +E E F C + +
Sbjct: 576 NEMGIAALRRVLTAYAFRNPNIGYCQAMNIVTSVLLLYAKEE-EAFWLLVALCERMLPDY 634
Query: 164 PGRR----LIDQSFLAFESSCMTFGDLVNKYCQAAHKLMVAVSEDVLQVYADWQRWLF-G 218
R L+DQ F +L Y + M + + + W LF
Sbjct: 635 YNTRVVGALVDQG---------VFEELARDYVPQLYDCMQDLGV-ISTISLSWFLTLFLS 684
Query: 219 ELPLCYFARVFDVFLVEGYKVLYRVALAIL 248
+P V D F EG KV++++ALA+L
Sbjct: 685 VMPFESAVVVVDCFFYEGIKVIFQLALAVL 714
>gi|21687020 ecotropic viral integration site 5-like isoform 2 [Homo
sapiens]
Length = 794
Score = 44.3 bits (103), Expect = 3e-04
Identities = 71/332 (21%), Positives = 126/332 (37%), Gaps = 38/332 (11%)
Query: 35 LKQLARQGYWAQSHALRGKVYQRLIR--DIPCRTVTPDASVYSDIVGKIVGKHSSSCLPL 92
LK+L R+G H R V+Q L D+P + + S K++ + + P
Sbjct: 108 LKELIRKGI---PHHFRAIVWQLLCSATDMPVKNQYSELLKMSSPCEKLIRRDIARTYPE 164
Query: 93 PEFVDNTQVPSYCLNARGEGAVRKILLCLANQFPDISFCPALPAVVALLLHYSIDEAECF 152
EF ++ G+ + ++ + ++ +C +V LLL + E E F
Sbjct: 165 HEFFKGQ-------DSLGQEVLFNVMKAYSLVDREVGYCQGSAFIVGLLL-MQMPEEEAF 216
Query: 153 EKACRILACNDPGRRLIDQSFLAFESSCMTFGDLVNKYCQAAHKLMVAVSEDVLQVYADW 212
R++ R L S F ++ + + + S + W
Sbjct: 217 CVFVRLMQ-EYRLRELFKPSMAELGLCIYQFEYMLQEQLPDLNTHFRSQSFHTSMYASSW 275
Query: 213 QRWLF-GELPLCYFARVFDVFLVEGYKVLYRVALAIL----------------KFFHKVR 255
LF PL RVFD+F+ EG ++++RV LA+L ++F +V
Sbjct: 276 FLTLFLTTFPLPVATRVFDIFMYEGLEIVFRVGLALLQVNQAELMQLDMEGMSQYFQRV- 334
Query: 256 AGQPLESDSVKQDIRTFVRDIAKTVSPEKLLEKAFAIRLFSRKE--IQLLQMANEKALKQ 313
P + DS + + K LEK +A E I++ ++ E L +
Sbjct: 335 --IPHQFDSCPDKLVLKAYQVKYNPKKMKRLEKEYAAMKSKEMEEQIEIKRLRTENRLLK 392
Query: 314 KGITVKQKRQFVHLAVHAENF--RSEIVSVRE 343
+ I +K Q EN+ + E+ VR+
Sbjct: 393 QRIETLEKGQVTRAQEAEENYVIKRELAVVRQ 424
>gi|205360930 hypothetical protein LOC57707 [Homo sapiens]
Length = 456
Score = 44.3 bits (103), Expect = 3e-04
Identities = 46/201 (22%), Positives = 74/201 (36%), Gaps = 60/201 (29%)
Query: 362 LLFSSLQHGYSLARFYFQCEGHEPTLLLIKTTQKEVCGAYLSTDWSERNKFGGKLGFFGT 421
LLFSS HG+S ++ P + +++ K V G + S W + +F G
Sbjct: 268 LLFSSELHGHSFSQLCGHITHRGPCVAVLEDHDKHVFGGFASCSWEVKPQFQ------GD 321
Query: 422 GECFVFRLQPEVQRYEWVVIKHPELTKPPPLMAAEPTAPLSHSASSDPADRLSPFLAARH 481
CF+F + P + Y +H+ +D H
Sbjct: 322 NRCFLFSICPSMAVY-------------------------THTGYND------------H 344
Query: 482 FNLPSKTESMFMAGGSDCLIVG-GGGGQ----ALYIDGDLNRGRT---SHCDTFNNQPL- 532
+ M++ G + G G GGQ L++D D +G + C T+N+ L
Sbjct: 345 Y--------MYLNHGQQTIPNGLGMGGQHNYFGLWVDVDFGKGHSRAKPTCTTYNSPQLS 396
Query: 533 CSENFLIAAVEAWGFQDPDTQ 553
ENF +E W DP +
Sbjct: 397 AQENFQFDKMEVWAVGDPSEE 417
>gi|38348348 TBC1 domain family, member 10C [Homo sapiens]
Length = 446
Score = 43.9 bits (102), Expect = 4e-04
Identities = 38/143 (26%), Positives = 59/143 (41%), Gaps = 8/143 (5%)
Query: 110 GEGAVRKILLCLANQFPDISFCPAL-PAVVALLLHYSIDEAE-CFEKACRILACNDPGRR 167
G+ + ++L P+ +C A P LL+H +EA C + C + G
Sbjct: 156 GQQGLLQVLKAYTLYRPEQGYCQAQGPVAAVLLMHLPPEEAFWCLVQICEVYLPGYYGPH 215
Query: 168 LIDQSFLAFESSCMTFGDLVNKYCQAAHKLMVAVSEDVLQVYADWQRWLFGE-LPLCYFA 226
+ A F L+ + HK + V L +W LF LP
Sbjct: 216 ME-----AVRLDAEVFMALLRRLLPHVHKHLQQVGVGPLLYLPEWFLCLFARSLPFPTVL 270
Query: 227 RVFDVFLVEGYKVLYRVALAILK 249
RV+D FL EG +VL+RV L +++
Sbjct: 271 RVWDAFLSEGARVLFRVGLTLVR 293
>gi|114688046 TBC1 domain family, member 4 [Homo sapiens]
Length = 1298
Score = 42.7 bits (99), Expect = 9e-04
Identities = 70/348 (20%), Positives = 144/348 (41%), Gaps = 44/348 (12%)
Query: 31 ELQELKQLARQGYWAQSHALRGKVYQ------RLIRDIPCRTVTPDASVYSDIVGKIVGK 84
+++++ L ++G + RG+++Q RL +P + PD S Y +++ ++ +
Sbjct: 907 DMEDIHTLLKEGV---PKSRRGEIWQFLALQYRLRHRLPNKQQPPDIS-YKELLKQLTAQ 962
Query: 85 HSSSCLPLPEFVDNTQVPSYCLNARGEGAVRKILLCLANQFPDISFCPALPAVVA-LLLH 143
+ + L S L G+ ++ +L + ++ +C + V LLLH
Sbjct: 963 QHAILVDLGRTFPTHPYFSVQLGP-GQLSLFNLLKAYSLLDKEVGYCQGISFVAGVLLLH 1021
Query: 144 YSIDEAECFEKACRILACNDPGRRLIDQSFLAFESSCMTFGDLVNKYCQAAHKLMVAVSE 203
S E + FE + L + R+ ++ + L++ Y + + +
Sbjct: 1022 MS--EEQAFEML-KFLMYDLGFRKQYRPDMMSLQIQMYQLSRLLHDYHRDLYNHLEENEI 1078
Query: 204 DVLQVYADWQRWLFG-ELPLCYFARVFDVFLVEGYKVLYRVALAILKF------------ 250
A W LF + L + ARVFD+ ++G +V+++VAL++L
Sbjct: 1079 SPSLYAAPWFLTLFASQFSLGFVARVFDIIFLQGTEVIFKVALSLLSSQETLIMECESFE 1138
Query: 251 ----FHKVRAGQPLESDSVKQDIRTFVRDIAKT---------VSPEKLLEKAFAIRLFSR 297
F K S+ K + F DI+K V ++L E +++
Sbjct: 1139 NIVEFLKNTLPDMNTSEMEKIITQVFEMDISKQLHAYEVEYHVLQDELQESSYSCE--DS 1196
Query: 298 KEIQLLQMANEKALKQKGITVKQKRQFVHLAVHAENFRSEIVSVREMR 345
+ ++ L+ AN + LK++ + + +K Q H + A E + RE +
Sbjct: 1197 ETLEKLERANSQ-LKRQNMDLLEKLQVAHTKIQALESNLENLLTRETK 1243
>gi|164519084 RAB GTPase activating protein 1 [Homo sapiens]
Length = 1069
Score = 42.0 bits (97), Expect = 0.001
Identities = 55/223 (24%), Positives = 90/223 (40%), Gaps = 20/223 (8%)
Query: 33 QELKQLARQGYWAQSHALRGKVYQRLIRDIPCRTVTPDASVYSDIVGKIVGKHSSSCLPL 92
++L L R G ALRG+V+Q L C Y ++ K + S+ +
Sbjct: 557 KQLSSLVRNGV---PEALRGEVWQLLAG---CHNNDHLVEKYRILITKESPQDSAITRDI 610
Query: 93 PEFVDNTQVPS--YCLNARGEGAVRKILLCLANQFPD--ISFCPALPAVVALLLHYSIDE 148
N P+ Y + G+G +C A D I +C + A+LL + + E
Sbjct: 611 -----NRTFPAHDYFKDTGGDGQDSLYKICKAYSVYDEEIGYCQGQSFLAAVLLLH-MPE 664
Query: 149 AECFEKACRILACNDPG-RRLIDQSFLAFESSCMTFGDLVNKYCQAAHKLMVAVSEDVLQ 207
+ F +I+ D G R L Q+F L+ +Y + + +S +
Sbjct: 665 EQAFSVLVKIMF--DYGLRELFKQNFEDLHCKFYQLERLMQEYIPDLYNHFLDISLEAHM 722
Query: 208 VYADWQRWLF-GELPLCYFARVFDVFLVEGYKVLYRVALAILK 249
+ W LF + PL + D+ L EG V++ VAL +LK
Sbjct: 723 YASQWFLTLFTAKFPLYMVFHIIDLLLCEGISVIFNVALGLLK 765
>gi|68299759 ecotropic viral integration site 5 [Homo sapiens]
Length = 810
Score = 41.6 bits (96), Expect = 0.002
Identities = 44/203 (21%), Positives = 90/203 (44%), Gaps = 29/203 (14%)
Query: 127 DISFCPALPAVVALLLHYSIDEAECFEKACRILACNDPGRRLIDQSFLAFESSCM-TFGD 185
++ +C +V LLL + E E F +++ D R + + +A CM F
Sbjct: 240 EVGYCQGSAFIVGLLL-MQMPEEEAFCVFVKLM--QDYRLRELFKPSMAELGLCMYQFEC 296
Query: 186 LVNKYCQAAHKLMVAVSEDVLQVYADWQRWLF-GELPLCYFARVFDVFLVEGYKVLYRVA 244
++ ++ + S + W +F PL R+FD+F+ EG ++++RV
Sbjct: 297 MIQEHLPELFVHFQSQSFHTSMYASSWFLTIFLTTFPLPIATRIFDIFMSEGLEIVFRVG 356
Query: 245 LAILKFFHKVRAGQPLESDSVKQDIRTFVRDIAKTVS------PEKLLEKAFAIRLFSRK 298
LA+L Q +++ ++ D+ ++ K + P+KL++ A+ ++ S+K
Sbjct: 357 LALL---------QMNQAELMQLDMEGMLQHFQKVIPHQFDGVPDKLIQAAYQVKYNSKK 407
Query: 299 EIQLLQMANEKALKQKGITVKQK 321
K L+++ T+K K
Sbjct: 408 ---------MKKLEKEYTTIKTK 421
>gi|148806902 TBC1 domain family, member 12 [Homo sapiens]
Length = 775
Score = 41.2 bits (95), Expect = 0.003
Identities = 43/175 (24%), Positives = 85/175 (48%), Gaps = 19/175 (10%)
Query: 126 PDISFCPALPAVVALLLHYSIDEAECFEKACRILACNDPGRRL---IDQSFLA--FESSC 180
PD+ + + + A+L+ +++EA+ F +L N P + +D S + F +
Sbjct: 583 PDVGYVQGMSFIAAVLI-LNLEEADAFIAFANLL--NKPCQLAFFRVDHSMMLKYFATFE 639
Query: 181 MTFGDLVNKYCQAAHKLMVAVSEDVLQVYADWQRWLFGE-LPLCYFARVFDVFLVEGYKV 239
+ F + ++K H +++ D+ + DW L+ + LPL RV+DVF +G +
Sbjct: 640 VFFEENLSKLF--LHFKSYSLTPDIYLI--DWIFTLYSKSLPLDLACRVWDVFCRDGEEF 695
Query: 240 LYRVALAILKFFHKVRAGQPLESDSVKQDIRTFVRDIAKTVSPEKLLEKAFAIRL 294
L+R L IL+ + + L+ D + I F+ + + ++ EKL AI++
Sbjct: 696 LFRTGLGILRLYEDIL----LQMDFI--HIAQFLTKLPEDITSEKLFSCIAAIQM 744
>gi|229577000 ecotropic viral integration site 5-like isoform 1
[Homo sapiens]
Length = 805
Score = 40.8 bits (94), Expect = 0.003
Identities = 60/269 (22%), Positives = 110/269 (40%), Gaps = 22/269 (8%)
Query: 35 LKQLARQGYWAQSHALRGKVYQRLIR--DIPCRTVTPDASVYSDIVGKIVGKHSSSCLPL 92
LK+L R+G H R V+Q L D+P + + S K++ + + P
Sbjct: 108 LKELIRKGI---PHHFRAIVWQLLCSATDMPVKNQYSELLKMSSPCEKLIRRDIARTYPE 164
Query: 93 PEFVDNTQVPSYCLNARGEGAVRKILLCLANQFPDISFCPALPAVVALLLHYSIDEAECF 152
EF ++ G+ + ++ + ++ +C +V LLL + E E F
Sbjct: 165 HEFFKGQ-------DSLGQEVLFNVMKAYSLVDREVGYCQGSAFIVGLLL-MQMPEEEAF 216
Query: 153 EKACRILACNDPGRRLIDQSFLAFESSCMTFGDLVNKYCQAAHKLMVAVSEDVLQVYADW 212
R++ R L S F ++ + + + S + W
Sbjct: 217 CVFVRLMQ-EYRLRELFKPSMAELGLCIYQFEYMLQEQLPDLNTHFRSQSFHTSMYASSW 275
Query: 213 QRWLF-GELPLCYFARVFDVFLVEGYKVLYRVALAILKFFHKVRAGQPLESDSVKQDIRT 271
LF PL RVFD+F+ EG ++++RV LA+L +V + ++ D ++ +
Sbjct: 276 FLTLFLTTFPLPVATRVFDIFMYEGLEIVFRVGLALL----QVNQAELMQLD-MEGMSQY 330
Query: 272 FVRDIAKTVS--PEKLLEKAFAIRLFSRK 298
F R I P+KL+ KA+ ++ +K
Sbjct: 331 FQRVIPHQFDSCPDKLVLKAYQVKYNPKK 359
>gi|29648315 small G protein signaling modulator 3 [Homo sapiens]
Length = 749
Score = 40.8 bits (94), Expect = 0.003
Identities = 42/200 (21%), Positives = 84/200 (42%), Gaps = 10/200 (5%)
Query: 50 LRGKVYQRLIRDIPCRTVTPDASVYSDIVGKIVGKHSSSCLPLPEFVDNTQVPSYCLNAR 109
L G + ++ ++ R + ++S I K + K +P N S + +
Sbjct: 127 LSGALQKKRNSELSYREIVKNSSNDETIAAKQIEKDLLRTMP-----SNACFAS--MGSI 179
Query: 110 GEGAVRKILLCLANQFPDISFCPALPAVVALLLHYSIDEAECFEKACRILACNDPGRRLI 169
G +R++L LA +P+I +C V A LL + ++E + F I+ P
Sbjct: 180 GVPRLRRVLRALAWLYPEIGYCQGTGMVAACLLLF-LEEEDAFWMMSAIIEDLLPA-SYF 237
Query: 170 DQSFLAFESSCMTFGDLVNKYCQAAHKLMVAVSEDVLQVYADWQRWLFGE-LPLCYFARV 228
+ L ++ L+ +Y KL+ ++ + W F + + R+
Sbjct: 238 STTLLGVQTDQRVLRHLIVQYLPRLDKLLQEHDIELSLITLHWFLTAFASVVDIKLLLRI 297
Query: 229 FDVFLVEGYKVLYRVALAIL 248
+D+F EG +VL+++ L +L
Sbjct: 298 WDLFFYEGSRVLFQLTLGML 317
>gi|164565381 TBC1 domain family, member 14 isoform b [Homo sapiens]
Length = 413
Score = 40.0 bits (92), Expect = 0.006
Identities = 31/102 (30%), Positives = 49/102 (48%), Gaps = 28/102 (27%)
Query: 181 MTFGDLVNKYCQAA-----HKLM--------VAVSEDVLQVYADWQR-----------WL 216
+ F +L+NK CQ A H LM V E++ +++A +++ W+
Sbjct: 248 IAFSNLLNKPCQMAFFRVDHGLMLTYFAAFEVFFEENLPKLFAHFKKNNLTPDIYLIDWI 307
Query: 217 FG----ELPLCYFARVFDVFLVEGYKVLYRVALAILKFFHKV 254
F LPL R++DVF +G + L+R AL ILK F +
Sbjct: 308 FTLYSKSLPLDLACRIWDVFCRDGEEFLFRTALGILKLFEDI 349
>gi|164565368 TBC1 domain family, member 14 isoform a [Homo sapiens]
Length = 693
Score = 40.0 bits (92), Expect = 0.006
Identities = 31/102 (30%), Positives = 49/102 (48%), Gaps = 28/102 (27%)
Query: 181 MTFGDLVNKYCQAA-----HKLM--------VAVSEDVLQVYADWQR-----------WL 216
+ F +L+NK CQ A H LM V E++ +++A +++ W+
Sbjct: 528 IAFSNLLNKPCQMAFFRVDHGLMLTYFAAFEVFFEENLPKLFAHFKKNNLTPDIYLIDWI 587
Query: 217 FG----ELPLCYFARVFDVFLVEGYKVLYRVALAILKFFHKV 254
F LPL R++DVF +G + L+R AL ILK F +
Sbjct: 588 FTLYSKSLPLDLACRIWDVFCRDGEEFLFRTALGILKLFEDI 629
>gi|164565366 TBC1 domain family, member 14 isoform a [Homo sapiens]
Length = 693
Score = 40.0 bits (92), Expect = 0.006
Identities = 31/102 (30%), Positives = 49/102 (48%), Gaps = 28/102 (27%)
Query: 181 MTFGDLVNKYCQAA-----HKLM--------VAVSEDVLQVYADWQR-----------WL 216
+ F +L+NK CQ A H LM V E++ +++A +++ W+
Sbjct: 528 IAFSNLLNKPCQMAFFRVDHGLMLTYFAAFEVFFEENLPKLFAHFKKNNLTPDIYLIDWI 587
Query: 217 FG----ELPLCYFARVFDVFLVEGYKVLYRVALAILKFFHKV 254
F LPL R++DVF +G + L+R AL ILK F +
Sbjct: 588 FTLYSKSLPLDLACRIWDVFCRDGEEFLFRTALGILKLFEDI 629
>gi|156231067 TBC1 domain family, member 8 [Homo sapiens]
Length = 1140
Score = 40.0 bits (92), Expect = 0.006
Identities = 38/186 (20%), Positives = 80/186 (43%), Gaps = 10/186 (5%)
Query: 70 DASVYSDIVGKIVGKHSSSCLPLPEFVD---NTQVPSYCL--NARGEGAVRKILLCLANQ 124
D + + G +V + C + E ++ + +P + N G A+R++L A++
Sbjct: 524 DLASHPGYYGNLVEESLGKCCLVTEEIERDLHRSLPEHPAFQNETGIAALRRVLTAYAHR 583
Query: 125 FPDISFCPALPAVVALLLHYSIDEAECFEKACRILACNDPGRRLIDQSFLAFESSCMTFG 184
P I +C ++ + ++LL Y+ +E + + C + + + F
Sbjct: 584 NPKIGYCQSMNILTSVLLLYTKEEEAFW---LLVAVCERMLPDYFNHRVIGAQVDQSVFE 640
Query: 185 DLVNKYCQAAHKLMVAVSEDVLQVYADWQRWLF-GELPLCYFARVFDVFLVEGYKVLYRV 243
+L+ + + M +S + V W LF +PL V D F +G K ++++
Sbjct: 641 ELIKGHLPELAEHMNDLSA-LASVSLSWFLTLFLSIMPLESAVNVVDCFFYDGIKAIFQL 699
Query: 244 ALAILK 249
LA+L+
Sbjct: 700 GLAVLE 705
>gi|50658061 TBC1 (tre-2/USP6, BUB2, cdc16) domain family, member 1
[Homo sapiens]
Length = 1168
Score = 38.9 bits (89), Expect = 0.012
Identities = 44/198 (22%), Positives = 90/198 (45%), Gaps = 9/198 (4%)
Query: 110 GEGAVRKILLCLANQFPDISFCPALPAVVA-LLLHYSIDEAECFEKACRILACNDPGRRL 168
G+ ++ IL + ++ +C L V LLLH S +EA K + L + R+
Sbjct: 869 GQLSLYNILKAYSLLDQEVGYCQGLSFVAGILLLHMSEEEAF---KMLKFLMFDMGLRKQ 925
Query: 169 IDQSFLAFESSCMTFGDLVNKYCQAAHKLMVAVSEDVLQVYADWQRWLFG-ELPLCYFAR 227
+ + L++ Y + + + A W +F + PL + AR
Sbjct: 926 YRPDMIILQIQMYQLSRLLHDYHRDLYNHLEEHEIGPSLYAAPWFLTMFASQFPLGFVAR 985
Query: 228 VFDVFLVEGYKVLYRVALAILKFFHKVRAGQPLESDSVKQDIRTFVRDIAKTVSPEKLLE 287
VFD+ ++G +V+++VAL++L HK Q +++ I++ + ++ V EK +
Sbjct: 986 VFDMIFLQGTEVIFKVALSLLG-SHKPLILQHENLETIVDFIKSTLPNLG-LVQMEKTIN 1043
Query: 288 KAFAIRLFSRKEIQLLQM 305
+ F + + K++Q ++
Sbjct: 1044 QVFEMDI--AKQLQAYEV 1059
>gi|78217386 RAB GTPase activating protein 1-like isoform A [Homo
sapiens]
Length = 815
Score = 38.9 bits (89), Expect = 0.012
Identities = 36/143 (25%), Positives = 59/143 (41%), Gaps = 7/143 (4%)
Query: 110 GEGAVRKILLCLANQFPDISFCPALPAVVA-LLLHYSIDEAECFEKACRILACNDPGRR- 167
G+ ++ KI + DI +C + A LLLH ++A C + D G R
Sbjct: 599 GQESLYKICKAYSVYDEDIGYCQGQSFLAAVLLLHMPEEQAFCV----LVKIMYDYGLRD 654
Query: 168 LIDQSFLAFESSCMTFGDLVNKYCQAAHKLMVAVSEDVLQVYADWQRWLF-GELPLCYFA 226
L +F L+ + H ++ + + W LF + PLC
Sbjct: 655 LYRNNFEDLHCKFYQLERLMQEQLPDLHSHFSDLNLEAHMYASQWFLTLFTAKFPLCMVF 714
Query: 227 RVFDVFLVEGYKVLYRVALAILK 249
+ D+ L EG +++ VALA+LK
Sbjct: 715 HIIDLLLCEGLNIIFHVALALLK 737
>gi|38570101 TBC1 domain family, member 8B (with GRAM domain)
isoform a [Homo sapiens]
Length = 1120
Score = 36.6 bits (83), Expect = 0.062
Identities = 39/149 (26%), Positives = 66/149 (44%), Gaps = 19/149 (12%)
Query: 110 GEGAVRKILLCLANQFPDISFCPALPAVVALLLHYSIDEAECF---EKACRILACNDPGR 166
G A+R++L A + P I +C A+ + ++LL Y+ +E E F C + + R
Sbjct: 551 GISALRRVLTAYAYRNPKIGYCQAMNILTSVLLLYAKEE-EAFWLLVAVCERMLPDYFNR 609
Query: 167 R----LIDQSFLAFESSCMTFGDLVNKYCQAAHKLMVAVSEDVLQVYADWQRWLF-GELP 221
R L+DQ+ F +L+ + + M ++ V W LF LP
Sbjct: 610 RIIGALVDQA---------VFEELIRDHLPQLTEHMTDMTF-FSSVSLSWFLTLFISVLP 659
Query: 222 LCYFARVFDVFLVEGYKVLYRVALAILKF 250
+ V D F +G K + ++ LAIL +
Sbjct: 660 IESAVNVVDCFFYDGIKAILQLGLAILDY 688
>gi|118722351 growth hormone regulated TBC protein 1 [Homo sapiens]
Length = 336
Score = 36.6 bits (83), Expect = 0.062
Identities = 33/137 (24%), Positives = 60/137 (43%), Gaps = 9/137 (6%)
Query: 117 ILLCLANQFPDISFCPALPAVVALLLHYSIDEAECFEKACRILACNDPGRRLIDQ---SF 173
+LL + + +C + + L+ + +E E F ++ GR L D +
Sbjct: 140 VLLAYGHHNQGVGYCQGMNFIAGYLILITNNEEESFWLLDALV-----GRILPDYYSPAM 194
Query: 174 LAFESSCMTFGDLVNKYCQAAHKLMVAVSEDVLQVYADWQRWLFGE-LPLCYFARVFDVF 232
L ++ G+LV A LM + + + W LF + LP+ R++D
Sbjct: 195 LGLKTDQEVLGELVRAKLPAVGALMERLGVLWTLLVSRWFICLFVDILPVETVLRIWDCL 254
Query: 233 LVEGYKVLYRVALAILK 249
EG K+++RVAL ++K
Sbjct: 255 FNEGSKIIFRVALTLIK 271
>gi|222352143 TBC1 domain family, member 2 [Homo sapiens]
Length = 917
Score = 32.3 bits (72), Expect = 1.2
Identities = 73/314 (23%), Positives = 124/314 (39%), Gaps = 59/314 (18%)
Query: 17 AAIQDLGPKELSCTELQELKQLARQGYWAQSHALRGKVYQRLIRDIPCRTVTPDASVYSD 76
AA+ DL P ELKQL R G + H R +V++ L+ TP Y +
Sbjct: 607 AALGDLVPSA-------ELKQLLRAGV-PREH--RPRVWRWLVHLRVQHLHTPGC--YQE 654
Query: 77 IVGKIVGKHSSSCLPLPEFVDNTQVPSY----CLNARGEGAVRKILLCLANQFPDISFCP 132
++ + + + + E N P+ C + +R++LL + Q P I +C
Sbjct: 655 LLSRGQAREHPAARQI-ELDLNRTFPNNKHFTCPTSSFPDKLRRVLLAFSWQNPTIGYCQ 713
Query: 133 ALPAVVALLLHYSIDEAECFEKACRILA--------CNDPGRRLIDQSFLAFESSCMTFG 184
L + A+ L +E F I+ CN +DQ L
Sbjct: 714 GLNRLAAIALLVLEEEESAFWCLVAIVETIMPADYYCNTLTASQVDQRVLQ--------- 764
Query: 185 DLVNKYCQAAHKLMVAVSE---DVLQVYADWQRWLFGE-LPLCYFARVFDVFLVEGYKVL 240
DL++ + +LM + + D+ V +W +F + L RV+D FL EG K
Sbjct: 765 DLLS---EKLPRLMAHLGQHHVDLSLVTFNWFLVVFADSLISNILLRVWDAFLYEGTKYN 821
Query: 241 YRVALAILKFFHKVRAGQPLESDSVKQDIRTFVRDIAKTVS-PEKLLEKAF-AIRLFSRK 298
+ L + +I ++R KT+S KL+ AF + F K
Sbjct: 822 EKEILRLQNGL----------------EIYQYLRFFTKTISNSRKLMNIAFNDMNPFRMK 865
Query: 299 EIQLLQMANEKALK 312
+++ L+M + + L+
Sbjct: 866 QLRQLRMVHRERLE 879
>gi|10092639 cysteine-rich motor neuron 1 [Homo sapiens]
Length = 1036
Score = 31.6 bits (70), Expect = 2.0
Identities = 31/133 (23%), Positives = 47/133 (35%), Gaps = 33/133 (24%)
Query: 93 PEFVDNTQVPSYCLNARGEGAVRKILLCLANQFPDI-SFCPALPAVVALLLHYSIDEAEC 151
P N VP+YC N G+ I L + PD+ + C + +V++ C
Sbjct: 741 PSLSRNNSVPNYCKNDEGD-----IFLAAESWKPDVCTSCICIDSVIS-----------C 784
Query: 152 FEKACRILACNDPGRRLIDQSFLAFESSCMTFGDLVNKYCQAAHKLMVAVSEDVLQVYAD 211
F ++C ++C P R + C YC V + YAD
Sbjct: 785 FSESCPSVSCERPVLR---------KGQCC-------PYCIEDTIPKKVVCHFSGKAYAD 828
Query: 212 WQRWLFGELPLCY 224
+RW CY
Sbjct: 829 EERWDLDSCTHCY 841
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.324 0.138 0.430
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 22,290,157
Number of Sequences: 37866
Number of extensions: 1024648
Number of successful extensions: 2487
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 26
Number of HSP's successfully gapped in prelim test: 20
Number of HSP's that attempted gapping in prelim test: 2439
Number of HSP's gapped (non-prelim): 53
length of query: 553
length of database: 18,247,518
effective HSP length: 107
effective length of query: 446
effective length of database: 14,195,856
effective search space: 6331351776
effective search space used: 6331351776
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (22.0 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.