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Search of human proteins with 8923390
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|8923390 coiled-coil-helix-coiled-coil-helix domain
containing 3 [Homo sapiens]
(227 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|8923390 coiled-coil-helix-coiled-coil-helix domain containing... 443 e-125
gi|14150134 coiled-coil-helix-coiled-coil-helix domain containin... 143 1e-34
gi|55749715 hypothetical protein LOC57536 [Homo sapiens] 48 6e-06
gi|4505101 microtubule-associated protein 7 [Homo sapiens] 48 8e-06
gi|102467235 inner centromere protein antigens 135/155kDa isofor... 48 8e-06
gi|102467242 inner centromere protein antigens 135/155kDa isofor... 48 8e-06
gi|44680105 caldesmon 1 isoform 1 [Homo sapiens] 47 1e-05
gi|134152708 arginine and glutamate rich 1 [Homo sapiens] 47 1e-05
gi|239735588 TRAF2 and NCK interacting kinase isoform 6 [Homo sa... 47 2e-05
gi|239735586 TRAF2 and NCK interacting kinase isoform 5 [Homo sa... 47 2e-05
gi|156766047 GRB10 interacting GYF protein 2 isoform c [Homo sap... 46 2e-05
gi|156766045 GRB10 interacting GYF protein 2 isoform a [Homo sap... 46 2e-05
gi|156766043 GRB10 interacting GYF protein 2 isoform b [Homo sap... 46 2e-05
gi|42476299 GRB10 interacting GYF protein 2 isoform b [Homo sapi... 46 2e-05
gi|239735580 TRAF2 and NCK interacting kinase isoform 2 [Homo sa... 46 3e-05
gi|55741807 TRAF2 and NCK interacting kinase isoform 1 [Homo sap... 46 3e-05
gi|122937382 Fas (TNFRSF6) binding factor 1 [Homo sapiens] 46 3e-05
gi|4506467 radixin [Homo sapiens] 45 4e-05
gi|195976782 Paf1/RNA polymerase II complex component [Homo sapi... 45 4e-05
gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo sap... 45 5e-05
gi|239745299 PREDICTED: hypothetical protein [Homo sapiens] 45 7e-05
gi|94721321 coiled-coil domain containing 11 [Homo sapiens] 44 9e-05
gi|148763347 cell division cycle 2-like 2 isoform 1 [Homo sapiens] 44 1e-04
gi|239745079 PREDICTED: Putative golgin subfamily A member 6-lik... 44 1e-04
gi|239735592 TRAF2 and NCK interacting kinase isoform 8 [Homo sa... 44 1e-04
gi|239735590 TRAF2 and NCK interacting kinase isoform 7 [Homo sa... 44 1e-04
gi|239735584 TRAF2 and NCK interacting kinase isoform 4 [Homo sa... 44 1e-04
gi|239735582 TRAF2 and NCK interacting kinase isoform 3 [Homo sa... 44 1e-04
gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens] 44 1e-04
gi|22758136 MAP7 domain containing 2 [Homo sapiens] 44 1e-04
>gi|8923390 coiled-coil-helix-coiled-coil-helix domain containing 3
[Homo sapiens]
Length = 227
Score = 443 bits (1140), Expect = e-125
Identities = 227/227 (100%), Positives = 227/227 (100%)
Query: 1 MGGTTSTRRVTFEADENENITVVKGIRLSENVIDRMKESSPSGSKSQRYSGAYGASVSDE 60
MGGTTSTRRVTFEADENENITVVKGIRLSENVIDRMKESSPSGSKSQRYSGAYGASVSDE
Sbjct: 1 MGGTTSTRRVTFEADENENITVVKGIRLSENVIDRMKESSPSGSKSQRYSGAYGASVSDE 60
Query: 61 ELKRRVAEELALEQAKKESEDQKRLKQAKELDRERAAANEQLTRAILRERICSEEERAKA 120
ELKRRVAEELALEQAKKESEDQKRLKQAKELDRERAAANEQLTRAILRERICSEEERAKA
Sbjct: 61 ELKRRVAEELALEQAKKESEDQKRLKQAKELDRERAAANEQLTRAILRERICSEEERAKA 120
Query: 121 KHLARQLEEKDRVLKKQDAFYKEQLARLEERSSEFYRVTTEQYQKAAEEVEAKFKRYESH 180
KHLARQLEEKDRVLKKQDAFYKEQLARLEERSSEFYRVTTEQYQKAAEEVEAKFKRYESH
Sbjct: 121 KHLARQLEEKDRVLKKQDAFYKEQLARLEERSSEFYRVTTEQYQKAAEEVEAKFKRYESH 180
Query: 181 PVCADLQAKILQCYRENTHQTLKCSALATQYMHCVNHAKQSMLEKGG 227
PVCADLQAKILQCYRENTHQTLKCSALATQYMHCVNHAKQSMLEKGG
Sbjct: 181 PVCADLQAKILQCYRENTHQTLKCSALATQYMHCVNHAKQSMLEKGG 227
>gi|14150134 coiled-coil-helix-coiled-coil-helix domain containing 6
[Homo sapiens]
Length = 235
Score = 143 bits (360), Expect = 1e-34
Identities = 84/236 (35%), Positives = 130/236 (55%), Gaps = 22/236 (9%)
Query: 1 MGGTTST--RRVTFEADENENITVVKGIRLSENVIDRMKESSPSGSKSQRYSGAYGASVS 58
MG T S+ RRV+F DE E + V++G+RLSENV++RMKE PS S +G +
Sbjct: 1 MGSTESSEGRRVSFGVDEEERVRVLQGVRLSENVVNRMKE--PSSPPPAPTSSTFG--LQ 56
Query: 59 DEELKRRVAEELALEQAKKESEDQKRLKQA-KELDRERAAANEQLTRAILRERICSEE-- 115
D L+ E + +K+ K ++E AA ++L + RER + +
Sbjct: 57 DGNLRAPHKESTLPRSGSSGGQQPSGMKEGVKRYEQEHAAIQDKLFQVAKREREAATKHS 116
Query: 116 -------------ERAKAKHLARQLEEKDRVLKKQDAFYKEQLARLEERSSEFYRVTTEQ 162
E K+ LAR+LE ++ L+++D FYKEQL R+E +++E Y++++EQ
Sbjct: 117 KASLPTGEGSISHEEQKSVRLARELESREAELRRRDTFYKEQLERIERKNAEMYKLSSEQ 176
Query: 163 YQKAAEEVEAKFKRYESHPVCADLQAKILQCYRENTHQTLKCSALATQYMHCVNHA 218
+ +AA ++E+ K PVC+ LQA+IL CYR+ H+ L CS L Y CV+ A
Sbjct: 177 FHEAASKMESTIKPRRVEPVCSGLQAQILHCYRDRPHEVLLCSDLVKAYQRCVSAA 232
>gi|55749715 hypothetical protein LOC57536 [Homo sapiens]
Length = 577
Score = 48.1 bits (113), Expect = 6e-06
Identities = 45/162 (27%), Positives = 77/162 (47%), Gaps = 17/162 (10%)
Query: 14 ADENENITVVKGIRLSENVIDRMKESSPSGSKSQRYSGAYGASVSDEELK---RRVAEEL 70
+DE +++ V GI NV R K SP + S AS+S E LK V E+
Sbjct: 21 SDEEQSVVYVPGISAEGNVRSRHKLMSPKADVKLKTSRVTDASISMESLKGTGDSVDEQN 80
Query: 71 ALEQAKKES-------EDQKRLKQAKELDRERAAANEQLTRAILRERICSEEERAKAKHL 123
+ K + ED++R+ L +E A +E+ + + ER+ +E+E + K
Sbjct: 81 SCRGEIKSASLKDLCLEDKRRI---ANLIKELARVSEE--KEVTEERLKAEQESFEKK-- 133
Query: 124 ARQLEEKDRVLKKQDAFYKEQLARLEERSSEFYRVTTEQYQK 165
RQLEE++ ++ K+ + Q +E S + + +EQ +K
Sbjct: 134 IRQLEEQNELIIKEREALQLQYRECQELLSLYQKYLSEQQEK 175
>gi|4505101 microtubule-associated protein 7 [Homo sapiens]
Length = 749
Score = 47.8 bits (112), Expect = 8e-06
Identities = 46/161 (28%), Positives = 79/161 (49%), Gaps = 20/161 (12%)
Query: 39 SSPSGSKSQRYSGAYGASVSD-EELKRRVAEE--LALEQAKKES---------EDQKRLK 86
S+PS + + S A +D EE R +AE+ LA EQ +KE E QKR +
Sbjct: 455 SAPSSTVNASASVKTSAGTTDPEEATRLLAEKRRLAREQREKEERERREQEELERQKREE 514
Query: 87 QAKELDRERAAANEQLTRAILRERICSEEERAKAKHLARQLEEKDRV-----LKKQDAFY 141
A+ + ER E+ +R + E+ +EE+ + + R L E++ K+++A
Sbjct: 515 LAQRVAEERTTRREEESRRLEAEQAREKEEQLQRQAEERALREREEAERAQRQKEEEARV 574
Query: 142 KEQLARL-EERSSEFYRVTTEQYQ--KAAEEVEAKFKRYES 179
+E+ R+ +ER F R E+ + K EE+ + +R E+
Sbjct: 575 REEAERVRQEREKHFQREEQERLERKKRLEEIMKRTRRTEA 615
Score = 43.5 bits (101), Expect = 1e-04
Identities = 36/122 (29%), Positives = 61/122 (50%), Gaps = 12/122 (9%)
Query: 60 EELKRRVAEELAL----EQAKKESEDQKRLKQAKELDRERAAANEQLTRAILRERICSEE 115
EEL+R+ EELA E+ + E+ +RL+ + ++E + RA LRER +E
Sbjct: 505 EELERQKREELAQRVAEERTTRREEESRRLEAEQAREKEEQLQRQAEERA-LREREEAER 563
Query: 116 ERAKAKHLARQLEEKDRVLKKQDA-FYKEQLARLEERSSEFYRVTTEQYQKAAEEVEAKF 174
+ + + AR EE +RV ++++ F +E+ RLE + E+ K EA
Sbjct: 564 AQRQKEEEARVREEAERVRQEREKHFQREEQERLERKK------RLEEIMKRTRRTEATD 617
Query: 175 KR 176
K+
Sbjct: 618 KK 619
Score = 31.6 bits (70), Expect = 0.58
Identities = 20/85 (23%), Positives = 42/85 (49%), Gaps = 8/85 (9%)
Query: 80 EDQKRLKQAKELDRERAAANEQLTRAILRERICSEEERAKAKHLARQLEEKDRVLKKQDA 139
+D++RL + + +RE+ A RE + E E +H + LEE+ + L++Q
Sbjct: 64 DDRQRLARERREEREKQLA--------AREIVWLEREERARQHYEKHLEERKKRLEEQRQ 115
Query: 140 FYKEQLARLEERSSEFYRVTTEQYQ 164
+ + A +EE+ + E+++
Sbjct: 116 KEERRRAAVEEKRRQRLEEDKERHE 140
Score = 30.0 bits (66), Expect = 1.7
Identities = 19/76 (25%), Positives = 37/76 (48%), Gaps = 4/76 (5%)
Query: 108 RERICSEEERAKAKHLARQ----LEEKDRVLKKQDAFYKEQLARLEERSSEFYRVTTEQY 163
R+R+ E + K LA + LE ++R + + +E+ RLEE+ + R
Sbjct: 66 RQRLARERREEREKQLAAREIVWLEREERARQHYEKHLEERKKRLEEQRQKEERRRAAVE 125
Query: 164 QKAAEEVEAKFKRYES 179
+K + +E +R+E+
Sbjct: 126 EKRRQRLEEDKERHEA 141
Score = 27.7 bits (60), Expect = 8.4
Identities = 19/63 (30%), Positives = 34/63 (53%), Gaps = 9/63 (14%)
Query: 60 EELKRRVAEELALEQAKKESEDQKRLKQAKELDRERAAANEQLTRAILRERICSEEERAK 119
EE K+R+ E+ E+ ++ + ++KR +Q E D+ER +E + R R ++ K
Sbjct: 104 EERKKRLEEQRQKEERRRAAVEEKR-RQRLEEDKER---HEAVVR-----RTMERSQKPK 154
Query: 120 AKH 122
KH
Sbjct: 155 QKH 157
>gi|102467235 inner centromere protein antigens 135/155kDa isoform 1
[Homo sapiens]
Length = 918
Score = 47.8 bits (112), Expect = 8e-06
Identities = 46/180 (25%), Positives = 87/180 (48%), Gaps = 14/180 (7%)
Query: 8 RRVTFEADENENITVVK-----GIRLSENVIDRMKESSPSGSKSQRYSGAYGASVSDEEL 62
RR E D+ + VK +R +R+++ K A +++
Sbjct: 555 RRQKVEEDKRRRLEEVKLKREERLRKVLQARERVEQMKEEKKKQIEQKFAQIDEKTEKAK 614
Query: 63 KRRVAEELALEQA--KKESEDQKRLKQAKELDRERAAANEQLTRA---ILRERICSEEER 117
+ R+AEE A ++A KK E + R KQ +E R R E+ R +L+++ E+ER
Sbjct: 615 EERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQEEEERRHQELLQKKKEEEQER 674
Query: 118 ----AKAKHLARQLEEKDRVLKKQDAFYKEQLARLEERSSEFYRVTTEQYQKAAEEVEAK 173
A+AK LA Q E++ R ++++ +EQ R +ER + ++ ++ ++ E ++A+
Sbjct: 675 LRKAAEAKRLAEQREQERREQERREQERREQERREQERREQERQLAEQERRREQERLQAE 734
Score = 43.5 bits (101), Expect = 1e-04
Identities = 39/121 (32%), Positives = 62/121 (51%), Gaps = 14/121 (11%)
Query: 59 DEELKRRVAEELAL-EQAKKESEDQKRLKQAKELDRERAAANEQLTRAILRERICSEEER 117
++E R+ AE L EQ ++E +Q+R +Q + R + R + + E+ER
Sbjct: 671 EQERLRKAAEAKRLAEQREQERREQERREQERREQERREQERREQERQLAEQERRREQER 730
Query: 118 AKAKHLARQLEEKDRVLKKQDAFYKEQLAR-LEE--RSSEFYRVTTEQYQKAAEEVEAKF 174
+A+ R+L+E+++ L+ Q KEQL R LEE + E R+ Q Q EE E K
Sbjct: 731 LQAE---RELQEREKALRLQ----KEQLQRELEEKKKKEEQQRLAERQLQ---EEQEKKA 780
Query: 175 K 175
K
Sbjct: 781 K 781
Score = 41.6 bits (96), Expect = 6e-04
Identities = 34/122 (27%), Positives = 62/122 (50%), Gaps = 9/122 (7%)
Query: 57 VSDEELKRRVAEELALEQAKKESEDQKRLKQAKELDRERAAANEQLTRAILRERICSEEE 116
+ EE +RR E L KK+ E+Q+RL++A E +R A + R RE+ E+E
Sbjct: 651 LQQEEEERRHQELLQ----KKKEEEQERLRKAAEA--KRLAEQREQER---REQERREQE 701
Query: 117 RAKAKHLARQLEEKDRVLKKQDAFYKEQLARLEERSSEFYRVTTEQYQKAAEEVEAKFKR 176
R + + ++ E++R L +Q+ +++ + E E + Q ++ E+E K K+
Sbjct: 702 RREQERREQERREQERQLAEQERRREQERLQAERELQEREKALRLQKEQLQRELEEKKKK 761
Query: 177 YE 178
E
Sbjct: 762 EE 763
Score = 34.7 bits (78), Expect = 0.069
Identities = 31/114 (27%), Positives = 63/114 (55%), Gaps = 12/114 (10%)
Query: 72 LEQAKKESEDQKRLKQAKELDRERAAANEQLTRAILRERICSEEERAKAKHLARQLEEKD 131
+E+ ++ E+ +R ++A++L R++ E+ R L E EER + AR+ E+
Sbjct: 535 VEKERQRLENLRRKEEAEQLRRQKV---EEDKRRRLEEVKLKREERLRKVLQARERVEQM 591
Query: 132 RVLKKQDAFYKEQLARLEERSSEFY--RVTTEQYQKAA-----EEVEAKFKRYE 178
+ KK+ +++ A+++E++ + R+ E+ +K A EEVEA+ K+ E
Sbjct: 592 KEEKKKQI--EQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEE 643
Score = 33.1 bits (74), Expect = 0.20
Identities = 23/65 (35%), Positives = 33/65 (50%), Gaps = 1/65 (1%)
Query: 60 EELKRRVAEELALEQAKKESEDQKRLKQAKELDRERAAANEQLTRAILRERICSEEERAK 119
E+ +RR E L E+ +E E RL Q ++L RE ++ + L ER EE+ K
Sbjct: 721 EQERRREQERLQAERELQEREKALRL-QKEQLQRELEEKKKKEEQQRLAERQLQEEQEKK 779
Query: 120 AKHLA 124
AK A
Sbjct: 780 AKEAA 784
Score = 32.3 bits (72), Expect = 0.34
Identities = 37/148 (25%), Positives = 68/148 (45%), Gaps = 15/148 (10%)
Query: 64 RRVAEELALEQAKKESEDQKRLKQAKELDRERAAANEQLTRAI-LRERI--CSEEERAKA 120
RR E L + K E + ++RL++ K L RE E+L + + RER+ EE++ +
Sbjct: 546 RRKEEAEQLRRQKVEEDKRRRLEEVK-LKRE-----ERLRKVLQARERVEQMKEEKKKQI 599
Query: 121 KHLARQLEEKDRVLKKQDAFYKEQLARLEERSSEFYRVTTEQYQKAAEEVEAKFKRYESH 180
+ Q++EK K +E+LA + + + E + +E EA+ R+
Sbjct: 600 EQKFAQIDEKTEKAK------EERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQ 653
Query: 181 PVCADLQAKILQCYRENTHQTLKCSALA 208
++LQ +E + L+ +A A
Sbjct: 654 EEEERRHQELLQKKKEEEQERLRKAAEA 681
Score = 30.4 bits (67), Expect = 1.3
Identities = 29/82 (35%), Positives = 45/82 (54%), Gaps = 9/82 (10%)
Query: 61 ELKRRVAEELALEQAKKESEDQKRLKQAKEL-DRERAAA--NEQLTRAILRERICSEEER 117
E +RR E EQ ++ +Q+RL+ +EL +RE+A EQL R L E+ EE++
Sbjct: 709 EQERREQERQLAEQERRR--EQERLQAERELQEREKALRLQKEQLQRE-LEEKKKKEEQQ 765
Query: 118 AKAKHLARQLEEKDRVLKKQDA 139
A+ RQL+E+ K+ A
Sbjct: 766 RLAE---RQLQEEQEKKAKEAA 784
>gi|102467242 inner centromere protein antigens 135/155kDa isoform 2
[Homo sapiens]
Length = 914
Score = 47.8 bits (112), Expect = 8e-06
Identities = 46/180 (25%), Positives = 87/180 (48%), Gaps = 14/180 (7%)
Query: 8 RRVTFEADENENITVVK-----GIRLSENVIDRMKESSPSGSKSQRYSGAYGASVSDEEL 62
RR E D+ + VK +R +R+++ K A +++
Sbjct: 551 RRQKVEEDKRRRLEEVKLKREERLRKVLQARERVEQMKEEKKKQIEQKFAQIDEKTEKAK 610
Query: 63 KRRVAEELALEQA--KKESEDQKRLKQAKELDRERAAANEQLTRA---ILRERICSEEER 117
+ R+AEE A ++A KK E + R KQ +E R R E+ R +L+++ E+ER
Sbjct: 611 EERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQEEEERRHQELLQKKKEEEQER 670
Query: 118 ----AKAKHLARQLEEKDRVLKKQDAFYKEQLARLEERSSEFYRVTTEQYQKAAEEVEAK 173
A+AK LA Q E++ R ++++ +EQ R +ER + ++ ++ ++ E ++A+
Sbjct: 671 LRKAAEAKRLAEQREQERREQERREQERREQERREQERREQERQLAEQERRREQERLQAE 730
Score = 43.5 bits (101), Expect = 1e-04
Identities = 39/121 (32%), Positives = 62/121 (51%), Gaps = 14/121 (11%)
Query: 59 DEELKRRVAEELAL-EQAKKESEDQKRLKQAKELDRERAAANEQLTRAILRERICSEEER 117
++E R+ AE L EQ ++E +Q+R +Q + R + R + + E+ER
Sbjct: 667 EQERLRKAAEAKRLAEQREQERREQERREQERREQERREQERREQERQLAEQERRREQER 726
Query: 118 AKAKHLARQLEEKDRVLKKQDAFYKEQLAR-LEE--RSSEFYRVTTEQYQKAAEEVEAKF 174
+A+ R+L+E+++ L+ Q KEQL R LEE + E R+ Q Q EE E K
Sbjct: 727 LQAE---RELQEREKALRLQ----KEQLQRELEEKKKKEEQQRLAERQLQ---EEQEKKA 776
Query: 175 K 175
K
Sbjct: 777 K 777
Score = 41.6 bits (96), Expect = 6e-04
Identities = 34/122 (27%), Positives = 62/122 (50%), Gaps = 9/122 (7%)
Query: 57 VSDEELKRRVAEELALEQAKKESEDQKRLKQAKELDRERAAANEQLTRAILRERICSEEE 116
+ EE +RR E L KK+ E+Q+RL++A E +R A + R RE+ E+E
Sbjct: 647 LQQEEEERRHQELLQ----KKKEEEQERLRKAAEA--KRLAEQREQER---REQERREQE 697
Query: 117 RAKAKHLARQLEEKDRVLKKQDAFYKEQLARLEERSSEFYRVTTEQYQKAAEEVEAKFKR 176
R + + ++ E++R L +Q+ +++ + E E + Q ++ E+E K K+
Sbjct: 698 RREQERREQERREQERQLAEQERRREQERLQAERELQEREKALRLQKEQLQRELEEKKKK 757
Query: 177 YE 178
E
Sbjct: 758 EE 759
Score = 35.4 bits (80), Expect = 0.040
Identities = 35/130 (26%), Positives = 66/130 (50%), Gaps = 11/130 (8%)
Query: 56 SVSDEELKRRVAEELALEQAKKESEDQKRLKQAKELDRERAAANEQLTRAILRERICSEE 115
SV +KR L ++ +KE + + L++ +E ++ R E+ R L E E
Sbjct: 514 SVMKSFIKRNTP--LRMDPKEKERQRLENLRRKEEAEQLRRQKVEEDKRRRLEEVKLKRE 571
Query: 116 ERAKAKHLARQLEEKDRVLKKQDAFYKEQLARLEERSSEFY--RVTTEQYQKAA-----E 168
ER + AR+ E+ + KK+ +++ A+++E++ + R+ E+ +K A E
Sbjct: 572 ERLRKVLQARERVEQMKEEKKKQI--EQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKME 629
Query: 169 EVEAKFKRYE 178
EVEA+ K+ E
Sbjct: 630 EVEARRKQEE 639
Score = 33.1 bits (74), Expect = 0.20
Identities = 23/65 (35%), Positives = 33/65 (50%), Gaps = 1/65 (1%)
Query: 60 EELKRRVAEELALEQAKKESEDQKRLKQAKELDRERAAANEQLTRAILRERICSEEERAK 119
E+ +RR E L E+ +E E RL Q ++L RE ++ + L ER EE+ K
Sbjct: 717 EQERRREQERLQAERELQEREKALRL-QKEQLQRELEEKKKKEEQQRLAERQLQEEQEKK 775
Query: 120 AKHLA 124
AK A
Sbjct: 776 AKEAA 780
Score = 32.3 bits (72), Expect = 0.34
Identities = 37/148 (25%), Positives = 68/148 (45%), Gaps = 15/148 (10%)
Query: 64 RRVAEELALEQAKKESEDQKRLKQAKELDRERAAANEQLTRAI-LRERI--CSEEERAKA 120
RR E L + K E + ++RL++ K L RE E+L + + RER+ EE++ +
Sbjct: 542 RRKEEAEQLRRQKVEEDKRRRLEEVK-LKRE-----ERLRKVLQARERVEQMKEEKKKQI 595
Query: 121 KHLARQLEEKDRVLKKQDAFYKEQLARLEERSSEFYRVTTEQYQKAAEEVEAKFKRYESH 180
+ Q++EK K +E+LA + + + E + +E EA+ R+
Sbjct: 596 EQKFAQIDEKTEKAK------EERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQ 649
Query: 181 PVCADLQAKILQCYRENTHQTLKCSALA 208
++LQ +E + L+ +A A
Sbjct: 650 EEEERRHQELLQKKKEEEQERLRKAAEA 677
Score = 30.4 bits (67), Expect = 1.3
Identities = 29/82 (35%), Positives = 45/82 (54%), Gaps = 9/82 (10%)
Query: 61 ELKRRVAEELALEQAKKESEDQKRLKQAKEL-DRERAAA--NEQLTRAILRERICSEEER 117
E +RR E EQ ++ +Q+RL+ +EL +RE+A EQL R L E+ EE++
Sbjct: 705 EQERREQERQLAEQERRR--EQERLQAERELQEREKALRLQKEQLQRE-LEEKKKKEEQQ 761
Query: 118 AKAKHLARQLEEKDRVLKKQDA 139
A+ RQL+E+ K+ A
Sbjct: 762 RLAE---RQLQEEQEKKAKEAA 780
>gi|44680105 caldesmon 1 isoform 1 [Homo sapiens]
Length = 793
Score = 47.0 bits (110), Expect = 1e-05
Identities = 48/168 (28%), Positives = 82/168 (48%), Gaps = 11/168 (6%)
Query: 16 ENENITVVKGIRLSENVIDRMKESSPSGSKSQRYSGAYGASVSDEELKRRVAEELALEQA 75
E++ TVV ++ + + K+ S S + + +E+ +R AE LE
Sbjct: 218 ESQEETVVMSLKNGQISSEEPKQEEEREQGSDEIS--HHEKMEEEDKERAEAERARLEAE 275
Query: 76 KKE---SEDQKRL--KQAKELDRERAAANEQLTR-AILRERICSEEERAKAKHLARQLEE 129
++E +E K++ ++A+ E+AAA E+ R A RER+ EE+RA A+ R EE
Sbjct: 276 ERERIKAEQDKKIADERARIEAEEKAAAQERERREAEERERMREEEKRA-AEERQRIKEE 334
Query: 130 KDRVLKKQDAFYKEQLARLEERS--SEFYRVTTEQYQKAAEEVEAKFK 175
+ R +++ +E+ EER E + E+ Q+A E E K K
Sbjct: 335 EKRAAEERQRIKEEEKRAAEERQRIKEEEKRAAEERQRARAEEEEKAK 382
Score = 42.4 bits (98), Expect = 3e-04
Identities = 41/175 (23%), Positives = 79/175 (45%), Gaps = 10/175 (5%)
Query: 9 RVTFEADENENITVVKGIRLSENVIDRMKESSPSGSKSQRYSGAYGASVSDEELKRRVAE 68
R EA+E E I + ++++ E + + +R + +EE +
Sbjct: 269 RARLEAEERERIKAEQDKKIADERARIEAEEKAAAQERERREAEERERMREEEKRAAEER 328
Query: 69 ELALEQAKKESEDQKRLK-QAKELDRERAAANEQLTRAI-LRERI-CSEEERAKAKHLAR 125
+ E+ K+ +E+++R+K + K ER E+ RA R+R EEE+AK + R
Sbjct: 329 QRIKEEEKRAAEERQRIKEEEKRAAEERQRIKEEEKRAAEERQRARAEEEEKAKVEEQKR 388
Query: 126 --QLEEKDRVLKKQDAFYKEQLARLE-----ERSSEFYRVTTEQYQKAAEEVEAK 173
QLEEK +++ ++ ++E E+ ++ ++ T +K EE K
Sbjct: 389 NKQLEEKKHAMQETKIKGEKVEQKIEGKWVNEKKAQEDKLQTAVLKKQGEEKGTK 443
Score = 37.7 bits (86), Expect = 0.008
Identities = 40/174 (22%), Positives = 74/174 (42%), Gaps = 18/174 (10%)
Query: 5 TSTRRVTFEADENENITVVKGIRLSE-------NVIDRMKESSPSGSKSQRYSGAYGASV 57
+ +R+ +E +E E TV K + ++ D+ KE + G V
Sbjct: 153 SESRQERYEIEETE--TVTKSYQKNDWRDAEENKKEDKEKEEEEEEKPKRGSIGENQVEV 210
Query: 58 SDEELKRRVAEELALEQAKKESEDQKRLKQAKELDRERAAANEQLTRAILRERICSEEER 117
EE EE + K + KQ + ER +++++ E ++ER
Sbjct: 211 MVEEKTTESQEETVVMSLKNGQISSEEPKQ----EEEREQGSDEISHHEKMEE--EDKER 264
Query: 118 AKAKHLARQLEEKDRVLKKQDAFYKEQLARLEERSSEFYRVTTEQYQKAAEEVE 171
A+A+ + EE++R+ +QD ++ AR+E +E E+ ++ AEE E
Sbjct: 265 AEAERARLEAEERERIKAEQDKKIADERARIE---AEEKAAAQERERREAEERE 315
Score = 35.0 bits (79), Expect = 0.053
Identities = 40/136 (29%), Positives = 60/136 (44%), Gaps = 26/136 (19%)
Query: 39 SSPSGSKSQRYSGAYGASVSD-----EELKRRVAEELALEQAKKESEDQKRLKQAKELDR 93
S P G S A GA + EEL+RR + + ESE+ ++LKQ ++
Sbjct: 511 SRPGGRASVDTKEAEGAPQVEAGKRLEELRRR--------RGETESEEFEKLKQKQQ--- 559
Query: 94 ERAAANEQLTRAILRERICSEEERAKAKHLARQLEEKDRVLKKQDAFYKEQLARLEERSS 153
E A E+L + R EEE + R+ EE DR L+++ E+ RL+E
Sbjct: 560 EAALELEELKKKREERRKVLEEEEQR-----RKQEEADRKLREE-----EEKRRLKEEIE 609
Query: 154 EFYRVTTEQYQKAAEE 169
E+ QK E+
Sbjct: 610 RRRAEAAEKRQKMPED 625
Score = 28.9 bits (63), Expect = 3.8
Identities = 30/121 (24%), Positives = 52/121 (42%), Gaps = 25/121 (20%)
Query: 61 ELKRRVAEELALEQAKKESEDQKRLKQAKELDRERAAANEQLTRAILRERICSEEERAKA 120
EL+R+ EE+ LE +R+ + D E AA E+ RA +ER+ ++E
Sbjct: 9 ELRRQKREEMRLEA--------ERIAYQRNDDDEEEAARERRRRA-RQERLRQKQEEESL 59
Query: 121 KHLARQLE----------------EKDRVLKKQDAFYKEQLARLEERSSEFYRVTTEQYQ 164
+ Q+E +V +A + E+LAR EER + + E+ +
Sbjct: 60 GQVTDQVEVNAQNSVPDEEAKTTTTNTQVEGDDEAAFLERLARREERRQKRLQEALERQK 119
Query: 165 K 165
+
Sbjct: 120 E 120
>gi|134152708 arginine and glutamate rich 1 [Homo sapiens]
Length = 273
Score = 47.0 bits (110), Expect = 1e-05
Identities = 38/126 (30%), Positives = 64/126 (50%), Gaps = 18/126 (14%)
Query: 59 DEELKRRVAEELALEQAKKESEDQKRLKQAK---------ELDRERAAANEQLTRAILRE 109
+E + +RV EEL + + E E +R+++AK EL+R+R A + +
Sbjct: 135 EELVAKRVEEELEKRKDEIEREVLRRVEEAKRIMEKQLLEELERQRQAE-------LAAQ 187
Query: 110 RICSEEERAKAKHLARQLEEKDRVLKKQDAFYKEQLARL--EERSSEFYRVTTEQYQKAA 167
+ EEERAK + L R LEE +R + + A E+ R+ E+R R+ EQ ++
Sbjct: 188 KAREEEERAKREELERILEENNRKIAEAQAKLAEEQLRIVEEQRKIHEERMKLEQERQRQ 247
Query: 168 EEVEAK 173
++ E K
Sbjct: 248 QKEEQK 253
Score = 42.7 bits (99), Expect = 3e-04
Identities = 32/149 (21%), Positives = 65/149 (43%), Gaps = 19/149 (12%)
Query: 64 RRVAEELALEQAKKESEDQKRLKQAKELDRERAAANEQLTRAILRERICSEEERAKAKHL 123
R V++ +L++ +K E++K+ E +R+R +++ ++ E E AK +
Sbjct: 87 RTVSKRSSLDEKQKREEEEKKA----EFERQRKIRQQEIEEKLIEEETARRVEELVAKRV 142
Query: 124 ARQLEEKDRVLKKQDAFYKEQLARLEERSSEFYRVTTEQYQK---------AAEEVEAKF 174
+LE K++D +E L R+EE + E+ ++ A E E +
Sbjct: 143 EEELE------KRKDEIEREVLRRVEEAKRIMEKQLLEELERQRQAELAAQKAREEEERA 196
Query: 175 KRYESHPVCADLQAKILQCYRENTHQTLK 203
KR E + + KI + + + L+
Sbjct: 197 KREELERILEENNRKIAEAQAKLAEEQLR 225
Score = 32.0 bits (71), Expect = 0.45
Identities = 26/85 (30%), Positives = 44/85 (51%), Gaps = 8/85 (9%)
Query: 60 EELKRRVAEELALEQAKKESEDQKR--LKQAKELDRERAA------ANEQLTRAILRERI 111
EEL+R+ ELA ++A++E E KR L++ E + + A A EQL + +I
Sbjct: 174 EELERQRQAELAAQKAREEEERAKREELERILEENNRKIAEAQAKLAEEQLRIVEEQRKI 233
Query: 112 CSEEERAKAKHLARQLEEKDRVLKK 136
E + + + +Q EE+ +L K
Sbjct: 234 HEERMKLEQERQRQQKEEQKIILGK 258
Score = 31.2 bits (69), Expect = 0.76
Identities = 28/119 (23%), Positives = 57/119 (47%), Gaps = 7/119 (5%)
Query: 74 QAKKESEDQKRL-KQAKELDRERAAANEQLTRAILRERICS--EEERAKAKHLARQLEEK 130
+++ S D++R+ K++K + +R E +R+ S E +R +A +++
Sbjct: 26 RSRSRSRDKERVRKRSKSRESKRNRRRESRSRSRSTNTAVSRRERDRERASSPPDRIDIF 85
Query: 131 DRVLKKQDAFYKEQLARLEERSSEFYRVTTEQYQKAAEEVEAKFKRYESHPVCADLQAK 189
R + K+ + ++Q EE+ +EF R Q + +E+E K E+ +L AK
Sbjct: 86 GRTVSKRSSLDEKQKREEEEKKAEFER----QRKIRQQEIEEKLIEEETARRVEELVAK 140
>gi|239735588 TRAF2 and NCK interacting kinase isoform 6 [Homo
sapiens]
Length = 1297
Score = 46.6 bits (109), Expect = 2e-05
Identities = 47/168 (27%), Positives = 80/168 (47%), Gaps = 17/168 (10%)
Query: 59 DEELKRRVAEELALEQAKKESEDQKRLKQAKELDRERAAANEQLTRAILRERICSEEERA 118
+EE KR++ E ++ +++ E ++RL++ + ++E E+ R E++ EEER
Sbjct: 380 NEEHKRQLLAERQ-KRIEEQKEQRRRLEEQQRREKELRKQQEREQRRHYEEQMRREEERR 438
Query: 119 KAKH----LARQLEEKDRVLK-KQDAFYKEQLARLE------ERSSEFYRVTTEQYQKAA 167
+A+H + RQLEE+ R L+ Q EQ LE E + R+ + Q+
Sbjct: 439 RAEHEQEYIRRQLEEEQRQLEILQQQLLHEQALLLEYKRKQLEEQRQAERLQRQLKQERD 498
Query: 168 EEVEAKFKRYESHPVCADLQAKILQCYRENTHQTLKCSALATQYMHCV 215
V + +R E PV + K L Y+E + K A A + H V
Sbjct: 499 YLVSLQHQRQEQRPV----EKKPLYHYKEGMSPSEK-PAWAKEIPHLV 541
Score = 42.0 bits (97), Expect = 4e-04
Identities = 41/167 (24%), Positives = 73/167 (43%), Gaps = 29/167 (17%)
Query: 70 LALEQAKKESEDQKRLKQAKELDRERAAANEQLTRAILRERICSEEERAKAKHLARQLEE 129
L L+ A KE + R +Q ++ RE NE+ R +L ER EE+ + + + +
Sbjct: 355 LRLQLANKERSEALRRQQLEQQQRE----NEEHKRQLLAERQKRIEEQKEQRRRLEEQQR 410
Query: 130 KDRVLKKQDA-----FYKEQLARLEER-----SSEFYRVTTEQYQKAAEEVEAKFKRYES 179
+++ L+KQ Y+EQ+ R EER E+ R E+ Q+ E ++ +
Sbjct: 411 REKELRKQQEREQRRHYEEQMRREEERRRAEHEQEYIRRQLEEEQRQLEILQQQLLHE-- 468
Query: 180 HPVCADLQAKILQCYRENTHQTLKCSALATQ------YMHCVNHAKQ 220
QA +L+ R+ + + L Q Y+ + H +Q
Sbjct: 469 -------QALLLEYKRKQLEEQRQAERLQRQLKQERDYLVSLQHQRQ 508
>gi|239735586 TRAF2 and NCK interacting kinase isoform 5 [Homo
sapiens]
Length = 1305
Score = 46.6 bits (109), Expect = 2e-05
Identities = 47/168 (27%), Positives = 80/168 (47%), Gaps = 17/168 (10%)
Query: 59 DEELKRRVAEELALEQAKKESEDQKRLKQAKELDRERAAANEQLTRAILRERICSEEERA 118
+EE KR++ E ++ +++ E ++RL++ + ++E E+ R E++ EEER
Sbjct: 380 NEEHKRQLLAERQ-KRIEEQKEQRRRLEEQQRREKELRKQQEREQRRHYEEQMRREEERR 438
Query: 119 KAKH----LARQLEEKDRVLK-KQDAFYKEQLARLE------ERSSEFYRVTTEQYQKAA 167
+A+H + RQLEE+ R L+ Q EQ LE E + R+ + Q+
Sbjct: 439 RAEHEQEYIRRQLEEEQRQLEILQQQLLHEQALLLEYKRKQLEEQRQAERLQRQLKQERD 498
Query: 168 EEVEAKFKRYESHPVCADLQAKILQCYRENTHQTLKCSALATQYMHCV 215
V + +R E PV + K L Y+E + K A A + H V
Sbjct: 499 YLVSLQHQRQEQRPV----EKKPLYHYKEGMSPSEK-PAWAKEIPHLV 541
Score = 42.0 bits (97), Expect = 4e-04
Identities = 41/167 (24%), Positives = 73/167 (43%), Gaps = 29/167 (17%)
Query: 70 LALEQAKKESEDQKRLKQAKELDRERAAANEQLTRAILRERICSEEERAKAKHLARQLEE 129
L L+ A KE + R +Q ++ RE NE+ R +L ER EE+ + + + +
Sbjct: 355 LRLQLANKERSEALRRQQLEQQQRE----NEEHKRQLLAERQKRIEEQKEQRRRLEEQQR 410
Query: 130 KDRVLKKQDA-----FYKEQLARLEER-----SSEFYRVTTEQYQKAAEEVEAKFKRYES 179
+++ L+KQ Y+EQ+ R EER E+ R E+ Q+ E ++ +
Sbjct: 411 REKELRKQQEREQRRHYEEQMRREEERRRAEHEQEYIRRQLEEEQRQLEILQQQLLHE-- 468
Query: 180 HPVCADLQAKILQCYRENTHQTLKCSALATQ------YMHCVNHAKQ 220
QA +L+ R+ + + L Q Y+ + H +Q
Sbjct: 469 -------QALLLEYKRKQLEEQRQAERLQRQLKQERDYLVSLQHQRQ 508
>gi|156766047 GRB10 interacting GYF protein 2 isoform c [Homo
sapiens]
Length = 1293
Score = 46.2 bits (108), Expect = 2e-05
Identities = 35/142 (24%), Positives = 74/142 (52%), Gaps = 9/142 (6%)
Query: 33 IDRMKESSPSGSKSQRYSGAYGASVSDEELKRRVAEELALEQA---KKESEDQKRLKQAK 89
+ +++++ + + +R A +EE KR+ EEL +Q +++ E++++ ++ +
Sbjct: 720 LQQLEKAKAAKLEQERREAEMRAKREEEERKRQ--EELRRQQEEILRRQQEEERKRREEE 777
Query: 90 ELDRERA--AANEQLTRAILRERICSEEERAKAKHLARQLEEKDRVLKKQDAFYKEQLAR 147
EL R + A Q + I R EEER + + R+LEE+ R ++++ +E+L R
Sbjct: 778 ELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRR--EEEERRKQEELLR 835
Query: 148 LEERSSEFYRVTTEQYQKAAEE 169
+E + + E+ Q+ EE
Sbjct: 836 KQEEEAAKWAREEEEAQRRLEE 857
Score = 44.3 bits (103), Expect = 9e-05
Identities = 39/140 (27%), Positives = 65/140 (46%), Gaps = 10/140 (7%)
Query: 27 RLSENVIDRMKESSPSGSKSQRYSGAYGASVSDEELKRRVAEELALEQAKKESEDQKRLK 86
R E ++ R +E + +R +E L+R+ +E+AL + ++E E Q++ +
Sbjct: 757 RQQEEILRRQQEEE----RKRREEEELARRKQEEALRRQREQEIALRRQREEEERQQQEE 812
Query: 87 QAKELDRERAAANEQLTRAILRERICSEEERAKAKHLARQLEEKDRVLKKQDAFYKEQLA 146
+ L+ R E+ + L + EEE AK AR+ EE R L++ +E+ A
Sbjct: 813 ALRRLEERRREEEERRKQEELLRK--QEEEAAK---WAREEEEAQRRLEENRLRMEEEAA 867
Query: 147 RLEERSSEFYRVTTE-QYQK 165
RL E R E Q QK
Sbjct: 868 RLRHEEEERKRKELEVQRQK 887
Score = 35.4 bits (80), Expect = 0.040
Identities = 43/162 (26%), Positives = 72/162 (44%), Gaps = 29/162 (17%)
Query: 31 NVIDRMKESSPSGSKSQRYSGAYGASVSDEELKRRVAEELALEQAKKESEDQKRLKQAKE 90
+V D +++ G ++ A + E +RR AE +AK+E E++KR ++ +
Sbjct: 702 SVWDLPLDTTTPGPALEQLQQLEKAKAAKLEQERREAEM----RAKREEEERKRQEELRR 757
Query: 91 LDRERAAANEQLTRAILRERICSEEERAKAKHLARQLEEKD-RVLKKQDAFYKEQ----- 144
E ILR + E +R + + LAR+ +E+ R ++Q+ + Q
Sbjct: 758 QQEE-----------ILRRQQEEERKRREEEELARRKQEEALRRQREQEIALRRQREEEE 806
Query: 145 -------LARLEE-RSSEFYRVTTEQYQKAAEEVEAKFKRYE 178
L RLEE R E R E+ + EE AK+ R E
Sbjct: 807 RQQQEEALRRLEERRREEEERRKQEELLRKQEEEAAKWAREE 848
>gi|156766045 GRB10 interacting GYF protein 2 isoform a [Homo
sapiens]
Length = 1320
Score = 46.2 bits (108), Expect = 2e-05
Identities = 35/142 (24%), Positives = 74/142 (52%), Gaps = 9/142 (6%)
Query: 33 IDRMKESSPSGSKSQRYSGAYGASVSDEELKRRVAEELALEQA---KKESEDQKRLKQAK 89
+ +++++ + + +R A +EE KR+ EEL +Q +++ E++++ ++ +
Sbjct: 747 LQQLEKAKAAKLEQERREAEMRAKREEEERKRQ--EELRRQQEEILRRQQEEERKRREEE 804
Query: 90 ELDRERA--AANEQLTRAILRERICSEEERAKAKHLARQLEEKDRVLKKQDAFYKEQLAR 147
EL R + A Q + I R EEER + + R+LEE+ R ++++ +E+L R
Sbjct: 805 ELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRR--EEEERRKQEELLR 862
Query: 148 LEERSSEFYRVTTEQYQKAAEE 169
+E + + E+ Q+ EE
Sbjct: 863 KQEEEAAKWAREEEEAQRRLEE 884
Score = 44.3 bits (103), Expect = 9e-05
Identities = 39/140 (27%), Positives = 65/140 (46%), Gaps = 10/140 (7%)
Query: 27 RLSENVIDRMKESSPSGSKSQRYSGAYGASVSDEELKRRVAEELALEQAKKESEDQKRLK 86
R E ++ R +E + +R +E L+R+ +E+AL + ++E E Q++ +
Sbjct: 784 RQQEEILRRQQEEE----RKRREEEELARRKQEEALRRQREQEIALRRQREEEERQQQEE 839
Query: 87 QAKELDRERAAANEQLTRAILRERICSEEERAKAKHLARQLEEKDRVLKKQDAFYKEQLA 146
+ L+ R E+ + L + EEE AK AR+ EE R L++ +E+ A
Sbjct: 840 ALRRLEERRREEEERRKQEELLRK--QEEEAAK---WAREEEEAQRRLEENRLRMEEEAA 894
Query: 147 RLEERSSEFYRVTTE-QYQK 165
RL E R E Q QK
Sbjct: 895 RLRHEEEERKRKELEVQRQK 914
Score = 35.4 bits (80), Expect = 0.040
Identities = 43/162 (26%), Positives = 72/162 (44%), Gaps = 29/162 (17%)
Query: 31 NVIDRMKESSPSGSKSQRYSGAYGASVSDEELKRRVAEELALEQAKKESEDQKRLKQAKE 90
+V D +++ G ++ A + E +RR AE +AK+E E++KR ++ +
Sbjct: 729 SVWDLPLDTTTPGPALEQLQQLEKAKAAKLEQERREAEM----RAKREEEERKRQEELRR 784
Query: 91 LDRERAAANEQLTRAILRERICSEEERAKAKHLARQLEEKD-RVLKKQDAFYKEQ----- 144
E ILR + E +R + + LAR+ +E+ R ++Q+ + Q
Sbjct: 785 QQEE-----------ILRRQQEEERKRREEEELARRKQEEALRRQREQEIALRRQREEEE 833
Query: 145 -------LARLEE-RSSEFYRVTTEQYQKAAEEVEAKFKRYE 178
L RLEE R E R E+ + EE AK+ R E
Sbjct: 834 RQQQEEALRRLEERRREEEERRKQEELLRKQEEEAAKWAREE 875
>gi|156766043 GRB10 interacting GYF protein 2 isoform b [Homo
sapiens]
Length = 1299
Score = 46.2 bits (108), Expect = 2e-05
Identities = 35/142 (24%), Positives = 74/142 (52%), Gaps = 9/142 (6%)
Query: 33 IDRMKESSPSGSKSQRYSGAYGASVSDEELKRRVAEELALEQA---KKESEDQKRLKQAK 89
+ +++++ + + +R A +EE KR+ EEL +Q +++ E++++ ++ +
Sbjct: 726 LQQLEKAKAAKLEQERREAEMRAKREEEERKRQ--EELRRQQEEILRRQQEEERKRREEE 783
Query: 90 ELDRERA--AANEQLTRAILRERICSEEERAKAKHLARQLEEKDRVLKKQDAFYKEQLAR 147
EL R + A Q + I R EEER + + R+LEE+ R ++++ +E+L R
Sbjct: 784 ELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRR--EEEERRKQEELLR 841
Query: 148 LEERSSEFYRVTTEQYQKAAEE 169
+E + + E+ Q+ EE
Sbjct: 842 KQEEEAAKWAREEEEAQRRLEE 863
Score = 44.3 bits (103), Expect = 9e-05
Identities = 39/140 (27%), Positives = 65/140 (46%), Gaps = 10/140 (7%)
Query: 27 RLSENVIDRMKESSPSGSKSQRYSGAYGASVSDEELKRRVAEELALEQAKKESEDQKRLK 86
R E ++ R +E + +R +E L+R+ +E+AL + ++E E Q++ +
Sbjct: 763 RQQEEILRRQQEEE----RKRREEEELARRKQEEALRRQREQEIALRRQREEEERQQQEE 818
Query: 87 QAKELDRERAAANEQLTRAILRERICSEEERAKAKHLARQLEEKDRVLKKQDAFYKEQLA 146
+ L+ R E+ + L + EEE AK AR+ EE R L++ +E+ A
Sbjct: 819 ALRRLEERRREEEERRKQEELLRK--QEEEAAK---WAREEEEAQRRLEENRLRMEEEAA 873
Query: 147 RLEERSSEFYRVTTE-QYQK 165
RL E R E Q QK
Sbjct: 874 RLRHEEEERKRKELEVQRQK 893
Score = 35.4 bits (80), Expect = 0.040
Identities = 43/162 (26%), Positives = 72/162 (44%), Gaps = 29/162 (17%)
Query: 31 NVIDRMKESSPSGSKSQRYSGAYGASVSDEELKRRVAEELALEQAKKESEDQKRLKQAKE 90
+V D +++ G ++ A + E +RR AE +AK+E E++KR ++ +
Sbjct: 708 SVWDLPLDTTTPGPALEQLQQLEKAKAAKLEQERREAEM----RAKREEEERKRQEELRR 763
Query: 91 LDRERAAANEQLTRAILRERICSEEERAKAKHLARQLEEKD-RVLKKQDAFYKEQ----- 144
E ILR + E +R + + LAR+ +E+ R ++Q+ + Q
Sbjct: 764 QQEE-----------ILRRQQEEERKRREEEELARRKQEEALRRQREQEIALRRQREEEE 812
Query: 145 -------LARLEE-RSSEFYRVTTEQYQKAAEEVEAKFKRYE 178
L RLEE R E R E+ + EE AK+ R E
Sbjct: 813 RQQQEEALRRLEERRREEEERRKQEELLRKQEEEAAKWAREE 854
>gi|42476299 GRB10 interacting GYF protein 2 isoform b [Homo
sapiens]
Length = 1299
Score = 46.2 bits (108), Expect = 2e-05
Identities = 35/142 (24%), Positives = 74/142 (52%), Gaps = 9/142 (6%)
Query: 33 IDRMKESSPSGSKSQRYSGAYGASVSDEELKRRVAEELALEQA---KKESEDQKRLKQAK 89
+ +++++ + + +R A +EE KR+ EEL +Q +++ E++++ ++ +
Sbjct: 726 LQQLEKAKAAKLEQERREAEMRAKREEEERKRQ--EELRRQQEEILRRQQEEERKRREEE 783
Query: 90 ELDRERA--AANEQLTRAILRERICSEEERAKAKHLARQLEEKDRVLKKQDAFYKEQLAR 147
EL R + A Q + I R EEER + + R+LEE+ R ++++ +E+L R
Sbjct: 784 ELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRR--EEEERRKQEELLR 841
Query: 148 LEERSSEFYRVTTEQYQKAAEE 169
+E + + E+ Q+ EE
Sbjct: 842 KQEEEAAKWAREEEEAQRRLEE 863
Score = 44.3 bits (103), Expect = 9e-05
Identities = 39/140 (27%), Positives = 65/140 (46%), Gaps = 10/140 (7%)
Query: 27 RLSENVIDRMKESSPSGSKSQRYSGAYGASVSDEELKRRVAEELALEQAKKESEDQKRLK 86
R E ++ R +E + +R +E L+R+ +E+AL + ++E E Q++ +
Sbjct: 763 RQQEEILRRQQEEE----RKRREEEELARRKQEEALRRQREQEIALRRQREEEERQQQEE 818
Query: 87 QAKELDRERAAANEQLTRAILRERICSEEERAKAKHLARQLEEKDRVLKKQDAFYKEQLA 146
+ L+ R E+ + L + EEE AK AR+ EE R L++ +E+ A
Sbjct: 819 ALRRLEERRREEEERRKQEELLRK--QEEEAAK---WAREEEEAQRRLEENRLRMEEEAA 873
Query: 147 RLEERSSEFYRVTTE-QYQK 165
RL E R E Q QK
Sbjct: 874 RLRHEEEERKRKELEVQRQK 893
Score = 35.4 bits (80), Expect = 0.040
Identities = 43/162 (26%), Positives = 72/162 (44%), Gaps = 29/162 (17%)
Query: 31 NVIDRMKESSPSGSKSQRYSGAYGASVSDEELKRRVAEELALEQAKKESEDQKRLKQAKE 90
+V D +++ G ++ A + E +RR AE +AK+E E++KR ++ +
Sbjct: 708 SVWDLPLDTTTPGPALEQLQQLEKAKAAKLEQERREAEM----RAKREEEERKRQEELRR 763
Query: 91 LDRERAAANEQLTRAILRERICSEEERAKAKHLARQLEEKD-RVLKKQDAFYKEQ----- 144
E ILR + E +R + + LAR+ +E+ R ++Q+ + Q
Sbjct: 764 QQEE-----------ILRRQQEEERKRREEEELARRKQEEALRRQREQEIALRRQREEEE 812
Query: 145 -------LARLEE-RSSEFYRVTTEQYQKAAEEVEAKFKRYE 178
L RLEE R E R E+ + EE AK+ R E
Sbjct: 813 RQQQEEALRRLEERRREEEERRKQEELLRKQEEEAAKWAREE 854
>gi|239735580 TRAF2 and NCK interacting kinase isoform 2 [Homo
sapiens]
Length = 1352
Score = 45.8 bits (107), Expect = 3e-05
Identities = 35/128 (27%), Positives = 69/128 (53%), Gaps = 10/128 (7%)
Query: 59 DEELKRRVAEELALEQAKKESEDQKRLKQAKELDRERAAANEQLTRAILRERICSEEERA 118
+EE KR++ E ++ +++ E ++RL++ + ++E E+ R E++ EEER
Sbjct: 380 NEEHKRQLLAERQ-KRIEEQKEQRRRLEEQQRREKELRKQQEREQRRHYEEQMRREEERR 438
Query: 119 KAKH----LARQLEEKDRVLKKQDAFYKEQLARLEERSSEFYRVTTEQYQKAAEEVEAKF 174
+A+H + RQLEE+ R L+ ++QL + E+ R E+ Q+ AE ++ +
Sbjct: 439 RAEHEQEYIRRQLEEEQRQLE----ILQQQLLHEQALLLEYKRKQLEE-QRQAERLQRQL 493
Query: 175 KRYESHPV 182
K+ + V
Sbjct: 494 KQERDYLV 501
Score = 42.0 bits (97), Expect = 4e-04
Identities = 41/167 (24%), Positives = 73/167 (43%), Gaps = 29/167 (17%)
Query: 70 LALEQAKKESEDQKRLKQAKELDRERAAANEQLTRAILRERICSEEERAKAKHLARQLEE 129
L L+ A KE + R +Q ++ RE NE+ R +L ER EE+ + + + +
Sbjct: 355 LRLQLANKERSEALRRQQLEQQQRE----NEEHKRQLLAERQKRIEEQKEQRRRLEEQQR 410
Query: 130 KDRVLKKQDA-----FYKEQLARLEER-----SSEFYRVTTEQYQKAAEEVEAKFKRYES 179
+++ L+KQ Y+EQ+ R EER E+ R E+ Q+ E ++ +
Sbjct: 411 REKELRKQQEREQRRHYEEQMRREEERRRAEHEQEYIRRQLEEEQRQLEILQQQLLHE-- 468
Query: 180 HPVCADLQAKILQCYRENTHQTLKCSALATQ------YMHCVNHAKQ 220
QA +L+ R+ + + L Q Y+ + H +Q
Sbjct: 469 -------QALLLEYKRKQLEEQRQAERLQRQLKQERDYLVSLQHQRQ 508
>gi|55741807 TRAF2 and NCK interacting kinase isoform 1 [Homo
sapiens]
Length = 1360
Score = 45.8 bits (107), Expect = 3e-05
Identities = 35/128 (27%), Positives = 69/128 (53%), Gaps = 10/128 (7%)
Query: 59 DEELKRRVAEELALEQAKKESEDQKRLKQAKELDRERAAANEQLTRAILRERICSEEERA 118
+EE KR++ E ++ +++ E ++RL++ + ++E E+ R E++ EEER
Sbjct: 380 NEEHKRQLLAERQ-KRIEEQKEQRRRLEEQQRREKELRKQQEREQRRHYEEQMRREEERR 438
Query: 119 KAKH----LARQLEEKDRVLKKQDAFYKEQLARLEERSSEFYRVTTEQYQKAAEEVEAKF 174
+A+H + RQLEE+ R L+ ++QL + E+ R E+ Q+ AE ++ +
Sbjct: 439 RAEHEQEYIRRQLEEEQRQLE----ILQQQLLHEQALLLEYKRKQLEE-QRQAERLQRQL 493
Query: 175 KRYESHPV 182
K+ + V
Sbjct: 494 KQERDYLV 501
Score = 42.0 bits (97), Expect = 4e-04
Identities = 41/167 (24%), Positives = 73/167 (43%), Gaps = 29/167 (17%)
Query: 70 LALEQAKKESEDQKRLKQAKELDRERAAANEQLTRAILRERICSEEERAKAKHLARQLEE 129
L L+ A KE + R +Q ++ RE NE+ R +L ER EE+ + + + +
Sbjct: 355 LRLQLANKERSEALRRQQLEQQQRE----NEEHKRQLLAERQKRIEEQKEQRRRLEEQQR 410
Query: 130 KDRVLKKQDA-----FYKEQLARLEER-----SSEFYRVTTEQYQKAAEEVEAKFKRYES 179
+++ L+KQ Y+EQ+ R EER E+ R E+ Q+ E ++ +
Sbjct: 411 REKELRKQQEREQRRHYEEQMRREEERRRAEHEQEYIRRQLEEEQRQLEILQQQLLHE-- 468
Query: 180 HPVCADLQAKILQCYRENTHQTLKCSALATQ------YMHCVNHAKQ 220
QA +L+ R+ + + L Q Y+ + H +Q
Sbjct: 469 -------QALLLEYKRKQLEEQRQAERLQRQLKQERDYLVSLQHQRQ 508
>gi|122937382 Fas (TNFRSF6) binding factor 1 [Homo sapiens]
Length = 1133
Score = 45.8 bits (107), Expect = 3e-05
Identities = 40/123 (32%), Positives = 63/123 (51%), Gaps = 10/123 (8%)
Query: 54 GASVSDEELKRRVAEELALEQAKKESEDQKRLKQAKELDRERAAANEQLTRAILRERICS 113
G DE+L R + E L +Q E E R +Q + + + A NEQ +R + +ER
Sbjct: 771 GIRQRDEQL-RALQERLGQQQRDMEEE---RSRQQEVIGKMEARLNEQ-SRLLEQERWRV 825
Query: 114 EEERAKAKHLARQLEEKDRVLKKQDAFYKEQLAR-----LEERSSEFYRVTTEQYQKAAE 168
E++KA+ + R LEE+ +V +Q A + +L R LEE+ S + E+ + AAE
Sbjct: 826 TAEQSKAESMQRALEEQRKVTAQQMAMERAELERAKSALLEEQKSVMLKCGEERRRLAAE 885
Query: 169 EVE 171
E
Sbjct: 886 WAE 888
Score = 40.0 bits (92), Expect = 0.002
Identities = 34/146 (23%), Positives = 66/146 (45%), Gaps = 5/146 (3%)
Query: 46 SQRYSGAYGASVSDEELKRRVAEELALEQAKKESEDQKRLKQAKELDRERAAANEQLTRA 105
+QR + ELK R A EL E+ + +E ++ +EL E+ E++
Sbjct: 912 TQREGTLISLAKEQAELKIR-ASELRAEEKQLAAERAALEQERQELRLEK----ERINAT 966
Query: 106 ILRERICSEEERAKAKHLARQLEEKDRVLKKQDAFYKEQLARLEERSSEFYRVTTEQYQK 165
LR ++ +EE + +K + + EE +R L++ EQ ARL+ + R+ ++
Sbjct: 967 ALRVKLRAEEVESMSKVASEKYEEGERALREAQQVQAEQQARLQAVQQQQERLRKQEQHM 1026
Query: 166 AAEEVEAKFKRYESHPVCADLQAKIL 191
E + +R + DL + ++
Sbjct: 1027 HQEHLSLAQQRLQLDRARQDLPSSLV 1052
>gi|4506467 radixin [Homo sapiens]
Length = 583
Score = 45.4 bits (106), Expect = 4e-05
Identities = 37/108 (34%), Positives = 56/108 (51%), Gaps = 4/108 (3%)
Query: 60 EELKRRVAE-ELALEQAKKESEDQKRLKQAKELDRERAAANEQLTRAILRERICSEEERA 118
EEL R+ + E +A+KE E+Q R +A ELD+ER A E+ R R E + A
Sbjct: 345 EELMERLKQIEEQTIKAQKELEEQTR--KALELDQERKRAKEEAERLEKERRAAEEAKSA 402
Query: 119 KAKHLARQLEEKDRVLKKQDAFYKEQLARLEERSSEFYRVTTEQYQKA 166
AK A Q++ +++ L + A + ++A LEE + TE KA
Sbjct: 403 IAKQAADQMKNQEQ-LAAELAEFTAKIALLEEAKKKKEEEATEWQHKA 449
Score = 42.4 bits (98), Expect = 3e-04
Identities = 31/124 (25%), Positives = 64/124 (51%), Gaps = 4/124 (3%)
Query: 55 ASVSDEELKRRVAEELALEQAKKESEDQKRLKQAKELDRERAAANEQLTRAILRERICSE 114
A + +E+ KR +AE+ E+ + E E ++ +++ K+++ + A ++L R+ + +
Sbjct: 321 AQLENEKKKREIAEK---EKERIEREKEELMERLKQIEEQTIKAQKELEEQT-RKALELD 376
Query: 115 EERAKAKHLARQLEEKDRVLKKQDAFYKEQLARLEERSSEFYRVTTEQYQKAAEEVEAKF 174
+ER +AK A +LE++ R ++ + +Q A + + E K A EAK
Sbjct: 377 QERKRAKEEAERLEKERRAAEEAKSAIAKQAADQMKNQEQLAAELAEFTAKIALLEEAKK 436
Query: 175 KRYE 178
K+ E
Sbjct: 437 KKEE 440
>gi|195976782 Paf1/RNA polymerase II complex component [Homo
sapiens]
Length = 710
Score = 45.4 bits (106), Expect = 4e-05
Identities = 39/141 (27%), Positives = 68/141 (48%), Gaps = 11/141 (7%)
Query: 38 ESSPSGSKSQRYSGAYGASVSDEELKRRVAEELALEQAKKESEDQKRLKQAKELDRERAA 97
E S S S S S +S DEE E+L ++ ED+ RL+Q E +RE+
Sbjct: 154 EVSDSDSNSSSSSSDSDSSSEDEEFHDGYGEDLMGDE-----EDRARLEQMTEKEREQEL 208
Query: 98 ANEQLTRAILRERICSEEERAKAKHLARQLEEKDRVLKKQDAFYKEQLARLEERSSEFYR 157
N R +L+ R E K A++ E+K++ K+++ K++L +++E S+
Sbjct: 209 FNRIEKREVLKRRF----EIKKKLKTAKKKEKKEKKKKQEEEQEKKKLTQIQE--SQVTS 262
Query: 158 VTTEQYQKAAEEVEAKFKRYE 178
E+ K E+++ K + E
Sbjct: 263 HNKERRSKRDEKLDKKSQAME 283
Score = 30.0 bits (66), Expect = 1.7
Identities = 29/134 (21%), Positives = 59/134 (44%), Gaps = 20/134 (14%)
Query: 60 EELKRRVAEELALEQAKK-ESEDQKRLKQAKELDRERAAANEQLTRAILRERICSEE--- 115
E LKRR + L+ AKK E +++K+ ++ ++ ++ E + +ER +
Sbjct: 216 EVLKRRFEIKKKLKTAKKKEKKEKKKKQEEEQEKKKLTQIQESQVTSHNKERRSKRDEKL 275
Query: 116 ------------ERAKAKHLARQLEEKDRVLKKQDAFYKEQLARLEERSSE----FYRVT 159
ER K K+ +L K + LK + + ++ +++SSE R +
Sbjct: 276 DKKSQAMEELKAEREKRKNRTAELLAKKQPLKTSEVYSDDEEEEEDDKSSEKSDRSSRTS 335
Query: 160 TEQYQKAAEEVEAK 173
+ ++ EE+ K
Sbjct: 336 SSDEEEEKEEIPPK 349
>gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo
sapiens]
Length = 570
Score = 45.1 bits (105), Expect = 5e-05
Identities = 29/148 (19%), Positives = 70/148 (47%), Gaps = 4/148 (2%)
Query: 34 DRMKESSPSGSKSQRYSGAYGASVSDEELKRRVAEELALEQAKKESEDQKRLKQAKELDR 93
+ M+E + + + ++E K R EE EQ KK E ++++++ +E+ +
Sbjct: 404 EMMQEQEEKMGEQEEKMWEQEEEMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQ 463
Query: 94 ERAAANEQLTRAILRERICSEEERAKAKHLARQLEEKDRVLKKQDAFYKEQLARLEERSS 153
E+ + + + +E+ K + ++ E+++ +++Q+ +EQ ++E+
Sbjct: 464 EQEEKMGEQEGKMCEQEAKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEE 523
Query: 154 EFYRVTT---EQYQKAAEEVEAKFKRYE 178
+ + EQ +K E+ E K +R E
Sbjct: 524 KMWEQEEKMCEQEEKMQEQ-EEKMRRQE 550
Score = 40.4 bits (93), Expect = 0.001
Identities = 23/123 (18%), Positives = 60/123 (48%), Gaps = 11/123 (8%)
Query: 34 DRMKESSPSGSKSQRYSGAYGASVSDEELKRRVAEELALEQAKKESEDQKRLKQAKELDR 93
++++E + + G + ++E K + EE Q +K E +K++++ +E R
Sbjct: 453 EKIREQEEMMQEQEEKMGEQEGKMCEQEAKMQEQEEKMRRQEEKIREQEKKIREQEEKIR 512
Query: 94 ERAAANEQLTRAILR--ERICSEEERAKAKHLARQLEEKDRVLKKQDAFYKEQLARLEER 151
E+ ++ + E++C +EE+ ++E++ +++Q+ +EQ RL ++
Sbjct: 513 EQEEMMQEQEEKMWEQEEKMCEQEEK---------MQEQEEKMRRQEEKMREQEVRLRQQ 563
Query: 152 SSE 154
+
Sbjct: 564 EEK 566
Score = 40.0 bits (92), Expect = 0.002
Identities = 31/128 (24%), Positives = 61/128 (47%), Gaps = 10/128 (7%)
Query: 60 EELKRRVAEELALEQAKKESEDQKRLKQAKELDRERAAANEQLTRAILRERICSEEERAK 119
E+ ++R EE EQ K++ ++ K +Q +++ + EQ +E E+E K
Sbjct: 361 EQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEMMQEQEEKMGEQEE-K 419
Query: 120 AKHLARQLEEKDRVLKKQDAFYKEQLARL---EERSSEFYRVTTEQYQKAAE------EV 170
+++E++ +++Q+ +EQ ++ EE+ E + EQ +K E E
Sbjct: 420 MWEQEEEMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMGEQEGKMCEQ 479
Query: 171 EAKFKRYE 178
EAK + E
Sbjct: 480 EAKMQEQE 487
Score = 38.9 bits (89), Expect = 0.004
Identities = 24/120 (20%), Positives = 62/120 (51%), Gaps = 8/120 (6%)
Query: 59 DEELKRRVAEELALEQAKKESEDQKRLKQAKELDRERAAANEQLTRAILRERICSEEERA 118
++E K R EE+ E+ +K E ++++ + +++ + E+ +RE+ +E+ A
Sbjct: 327 EKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEE---EKIREQEKRQEQEA 383
Query: 119 KAKHLARQLEEKDRVLKKQDAFYKEQLARLEERSSEFYRVTTEQYQKAAEEVEAKFKRYE 178
K ++ E++ +++Q+ +EQ ++ E+ + + + ++ +E E K +R E
Sbjct: 384 KMWRQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMW-----EQEEEMQEQEEKMRRQE 438
Score = 35.4 bits (80), Expect = 0.040
Identities = 29/126 (23%), Positives = 64/126 (50%), Gaps = 8/126 (6%)
Query: 57 VSDEELKRRVAEELALEQAKKESEDQKRLKQAKELDRERAAANEQLTRAIL-RERICSEE 115
+ ++E K R EE Q + E ++++++ +E+ E+ +L + +E+I +E
Sbjct: 304 IQEQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQE 363
Query: 116 ERAKAKHLARQLE---EKDRVLKKQDAFYKEQLARLEERSSEFYRVTTEQYQKAAEEVEA 172
E+ + + R+ E E++ + +Q+ +EQ EE+ E + EQ +K E+ E
Sbjct: 364 EKRQEEEKIREQEKRQEQEAKMWRQEEKIREQ----EEKIREQEEMMQEQEEKMGEQEEK 419
Query: 173 KFKRYE 178
+++ E
Sbjct: 420 MWEQEE 425
Score = 35.4 bits (80), Expect = 0.040
Identities = 30/123 (24%), Positives = 64/123 (52%), Gaps = 13/123 (10%)
Query: 59 DEELKRRVAEELALEQAKKESEDQKRLKQAKELDRERAAANE-QLTRAILRERICSEEER 117
++E K R EE EQ K +++KR ++ K ++E+ E ++ R E+I +EE+
Sbjct: 341 EKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQ--EEKIREQEEK 398
Query: 118 AKAKHLARQLEEKDRVLKKQDAFY---------KEQLARLEERSSEFYRVTTEQYQKAAE 168
+ + Q E+++++ ++++ + +E++ R EE+ E + EQ +K E
Sbjct: 399 IREQEEMMQ-EQEEKMGEQEEKMWEQEEEMQEQEEKMRRQEEKIREQEKKIREQEEKIRE 457
Query: 169 EVE 171
+ E
Sbjct: 458 QEE 460
Score = 32.3 bits (72), Expect = 0.34
Identities = 27/125 (21%), Positives = 60/125 (48%), Gaps = 11/125 (8%)
Query: 57 VSDEELKRRVAEELALEQAKKESEDQKRLKQAKE-LDRERAAANEQLTRAILRERICSEE 115
+ ++E + EE EQ +K E ++ +++ +E + R+ EQ ++I +E
Sbjct: 399 IREQEEMMQEQEEKMGEQEEKMWEQEEEMQEQEEKMRRQEEKIREQ------EKKIREQE 452
Query: 116 ERAKAKHLARQLEEKDRVLKKQDAFYKEQLARLEERSSEFYRVTTE--QYQKAAEEVEAK 173
E K + ++E++ + +Q+ EQ A+++E+ + R + + +K E E K
Sbjct: 453 E--KIREQEEMMQEQEEKMGEQEGKMCEQEAKMQEQEEKMRRQEEKIREQEKKIREQEEK 510
Query: 174 FKRYE 178
+ E
Sbjct: 511 IREQE 515
>gi|239745299 PREDICTED: hypothetical protein [Homo sapiens]
Length = 523
Score = 44.7 bits (104), Expect = 7e-05
Identities = 32/115 (27%), Positives = 60/115 (52%), Gaps = 15/115 (13%)
Query: 59 DEELKRRVAEELALEQAKKESEDQKRLKQAKELDRERAAANEQLTRAILRERICSEEERA 118
++E + R EE EQ ++ E ++RL++ +E RE+ ER+C +EER
Sbjct: 203 EQEERLREQEERLREQEERLCEQEERLREQEERLREQ------------EERLCEQEERL 250
Query: 119 KAKHLARQLEEKDRVLKKQDAF--YKEQLARLEERSSEFYRVTTEQYQKAAEEVE 171
+ +H R E+++R+ ++++ +E+L EER E EQ ++ E+ E
Sbjct: 251 R-EHEERLCEQEERLCEQEERLREQEERLHEQEERLCEQEERLREQEERLCEQEE 304
Score = 43.1 bits (100), Expect = 2e-04
Identities = 33/118 (27%), Positives = 59/118 (50%), Gaps = 7/118 (5%)
Query: 59 DEELKRRVAEELALEQAKKESEDQKRLKQAKE--LDRERAAANEQLTRAILRERICSEEE 116
++E + R EE EQ ++ E ++RL++ +E ++E + ER+C +EE
Sbjct: 210 EQEERLREQEERLCEQEERLREQEERLREQEERLCEQEERLREHEERLCEQEERLCEQEE 269
Query: 117 RAKAKHLARQLEEKDRVLKKQDAFYKEQLARL---EERSSEFYRVTTEQYQKAAEEVE 171
R + + +L E++ L +Q+ +EQ RL EER E EQ ++ E+ E
Sbjct: 270 RLREQE--ERLHEQEERLCEQEERLREQEERLCEQEERLREQEERLCEQEERLREQEE 325
Score = 41.2 bits (95), Expect = 7e-04
Identities = 29/114 (25%), Positives = 59/114 (51%), Gaps = 5/114 (4%)
Query: 59 DEELKRRVAEELALEQAKKESEDQKRLKQAKEL---DRERAAANEQLTRAILRERICSEE 115
++E + R EE EQ ++ E ++RL++ +E ER E+ R ER+C +E
Sbjct: 245 EQEERLREHEERLCEQEERLCEQEERLREQEERLHEQEERLCEQEERLRE-QEERLCEQE 303
Query: 116 ERAKAKHLARQLEEKDRVLKKQDAFYKEQLARLEERSSEFYRVTTEQYQKAAEE 169
ER + + R E+++R+ ++++ +++ +ER E EQ ++ E+
Sbjct: 304 ERLREQE-ERLCEQEERLREQEERLCEQEKLPGQERLLEEVEKLLEQERRQEEQ 356
Score = 34.3 bits (77), Expect = 0.090
Identities = 31/125 (24%), Positives = 57/125 (45%), Gaps = 18/125 (14%)
Query: 54 GASVSDEELKRRVAEELALEQAKKESEDQKRLKQAKELDRERAAANEQLTRAILRERICS 113
G + E ++ L Q ++ E ++RL++ +E RE+ ER+C
Sbjct: 177 GRQLQAEVENNQMLSLLNRRQEERLREQEERLREQEERLREQ------------EERLCE 224
Query: 114 EEERAKAKHLARQLEEKDRVLKKQDAFYKEQLARLEERSSEFYRVTTEQYQKAAEEVEAK 173
+EER + + +L E++ L +Q+ E+L EER E EQ ++ E+ E
Sbjct: 225 QEERLREQE--ERLREQEERLCEQE----ERLREHEERLCEQEERLCEQEERLREQEERL 278
Query: 174 FKRYE 178
++ E
Sbjct: 279 HEQEE 283
Score = 32.0 bits (71), Expect = 0.45
Identities = 27/92 (29%), Positives = 46/92 (50%), Gaps = 7/92 (7%)
Query: 59 DEELKRRVAEELALEQAKKESEDQKRLKQAKELDRERAAANEQLTRAILRERICSEEERA 118
++E + R EE EQ K +++ + K L++ER E+ R + RER+ E E
Sbjct: 315 EQEERLREQEERLCEQEKLPGQERLLEEVEKLLEQERR--QEEQERLLERERLLEEVEEL 372
Query: 119 KAKHLARQLEEKDRVLKKQDAFYKEQLARLEE 150
+ RQ +E+ L +Q+ ++L RL E
Sbjct: 373 LEQERLRQQDER---LWQQETL--QELERLRE 399
Score = 30.8 bits (68), Expect = 0.99
Identities = 28/97 (28%), Positives = 54/97 (55%), Gaps = 10/97 (10%)
Query: 61 ELKRRVAEELALEQAKKESEDQKRLK-QAKELDRERAAANEQLTRAILRERICSEEERAK 119
E ++ +E LE+ +K E ++R + Q + L+RER E++ + +ER+ ++ER
Sbjct: 329 EQEKLPGQERLLEEVEKLLEQERRQEEQERLLERERLL--EEVEELLEQERLRQQDERLW 386
Query: 120 AKHLARQLE---EKDRVLK-KQDAFYKEQLARLEERS 152
+ ++LE E +R+L+ +A Y++ R E RS
Sbjct: 387 QQETLQELERLRELERMLELGWEALYEQ---RAEPRS 420
>gi|94721321 coiled-coil domain containing 11 [Homo sapiens]
Length = 514
Score = 44.3 bits (103), Expect = 9e-05
Identities = 51/205 (24%), Positives = 88/205 (42%), Gaps = 28/205 (13%)
Query: 13 EADENENITVVKGIRLSENVIDRMKESSPSGSKSQRYSGAYGASVSDEELKRRVAEELAL 72
E D N + V + ++ + D+ K+ + Q+ Y A +EE + + L
Sbjct: 306 EQDLNMKL-VQRALQDLQEEADKKKQKREDMIREQKIYHKYLAQRREEEKAQEKEFDRIL 364
Query: 73 EQ--AKKESEDQKRLKQAKE-----LDRERAAANEQLTRAILRERICSEEERAKAKHLAR 125
E+ AKK +E K L+ KE +D Q+ + RE EE + KH+
Sbjct: 365 EEDKAKKLAEKDKELRLEKEARRQLVDEVMCTRKLQVQEKLQREAKEQEERAMEQKHI-- 422
Query: 126 QLEEKDRVLKKQDAFYKEQLARLEERSSEFYRVTTEQ--YQKAAEEVEAKFKRYE----- 178
+ LK+ + KE AR + + E+ + Q YQ+ ++E E + KR E
Sbjct: 423 -----NESLKELNCEEKENFARRQRLAQEYRKQLQMQIAYQQQSQEAEKEEKRREFEAGV 477
Query: 179 -SHPVCADLQAKILQCYRENTHQTL 202
++ +C D ++L +THQ L
Sbjct: 478 AANKMCLDKVQEVL-----STHQVL 497
>gi|148763347 cell division cycle 2-like 2 isoform 1 [Homo sapiens]
Length = 780
Score = 43.9 bits (102), Expect = 1e-04
Identities = 44/153 (28%), Positives = 68/153 (44%), Gaps = 12/153 (7%)
Query: 13 EADENENITVVKGIRLSENVIDRMKESSPSGSKSQRYSGAYG--ASVSDEELKRRVAEEL 70
E D++ I + + E V R E + +S G A V + E +RR
Sbjct: 78 EEDDSLAIKPPQQMSRKEKVHHRKDEKRKEKCRHHSHSAEGGKHARVKEREHERRKRHRE 137
Query: 71 ALEQAKKESEDQKRLKQAKELDRERAAANEQLTRAILRERICSEEERAKAKHLARQLEEK 130
++A++E E QKR + A+E R EQL R RER E+++ Q E+K
Sbjct: 138 EQDKARREWERQKRREMAREHSRRERDRLEQLERKRERERKMREQQK-------EQREQK 190
Query: 131 DRVLKKQDAFYKEQLARLEERSSEFYRVTTEQY 163
+R + ++ KE+ AR E S +R E Y
Sbjct: 191 ERERRAEER-RKEREARRE--VSAHHRTMREDY 220
Score = 36.6 bits (83), Expect = 0.018
Identities = 20/88 (22%), Positives = 38/88 (43%)
Query: 36 MKESSPSGSKSQRYSGAYGASVSDEELKRRVAEELALEQAKKESEDQKRLKQAKELDRER 95
+ +S S ++ S G+ +EE + EE + E E+++ ++ +E
Sbjct: 267 ISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNS 326
Query: 96 AAANEQLTRAILRERICSEEERAKAKHL 123
A+EQ + E + +EER HL
Sbjct: 327 EEASEQSAEEVSEEEMSEDEERENENHL 354
>gi|239745079 PREDICTED: Putative golgin subfamily A member 6-like
protein 6 [Homo sapiens]
Length = 724
Score = 43.9 bits (102), Expect = 1e-04
Identities = 27/129 (20%), Positives = 66/129 (51%), Gaps = 9/129 (6%)
Query: 59 DEELKRRVAEELALEQAKKESEDQKRLKQAKELDRERAAANEQLTRAI--LRERICSEEE 116
D+E K R EE Q +K E ++++++ +E RE+ ++ + E++C +EE
Sbjct: 568 DQEEKIREQEEKVWRQEEKIREQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEE 627
Query: 117 R-----AKAKHLARQLEEKDRVLKKQDAFYKEQLARLEERSSEFYRVTTE--QYQKAAEE 169
+ K + ++ E+++ +++Q+ +EQ ++E+ + + + + ++ +E
Sbjct: 628 KMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQE 687
Query: 170 VEAKFKRYE 178
E K +R E
Sbjct: 688 QEEKMRRQE 696
Score = 41.2 bits (95), Expect = 7e-04
Identities = 33/148 (22%), Positives = 69/148 (46%), Gaps = 7/148 (4%)
Query: 38 ESSPSGSKSQRYSGAYGASVSDEELKRRV---AEELALEQAKKESEDQKRLKQAKELDRE 94
E+ G + Q S A V + EL R+ EE Q +K E ++++++ +E RE
Sbjct: 327 EADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIRE 386
Query: 95 RAAANEQLTRAILRERICSEEERAKAKHLARQLEEKDRVLKKQDAFY---KEQLARLEER 151
+ + + R+ E+ K + + EK+ +++Q+ +E++ LEE+
Sbjct: 387 QEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEK 446
Query: 152 SSEFYRVTTEQYQKAAEE-VEAKFKRYE 178
E ++ ++ ++ EE + + KR E
Sbjct: 447 MHEQEKIREQEEKRQEEEKIREQEKRQE 474
Score = 38.9 bits (89), Expect = 0.004
Identities = 28/141 (19%), Positives = 66/141 (46%), Gaps = 19/141 (13%)
Query: 34 DRMKESSPSGSKSQRYSGAYGASVSDEELKRRVAEELALEQAKKESEDQKRLKQAKELDR 93
++++E + + G + ++E K + EE Q +K E +K++++ +E R
Sbjct: 599 EKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEEKMRRQEEKIREQEKKIREQEEKIR 658
Query: 94 ERAAANEQLTRAILR--ERICSEEERAKAKHLARQLEEKDRVLKKQDAFYKEQLARLEER 151
E+ ++ + E++C +EE+ ++E++ +++Q+ EQ RL ++
Sbjct: 659 EQEEMMQEQEEKMWEQEEKMCEQEEK---------MQEQEEKMRRQEEKMWEQEVRLRQQ 709
Query: 152 SSEFYRVTTEQYQKAAEEVEA 172
E+ Q+ E +EA
Sbjct: 710 E--------EKMQEHQEHLEA 722
Score = 37.7 bits (86), Expect = 0.008
Identities = 31/130 (23%), Positives = 65/130 (50%), Gaps = 10/130 (7%)
Query: 59 DEELKRRVAEELALEQAKKES-------EDQKRLKQAKELDRERAAANEQLTRAILRERI 111
++E K R EE+ E+ +K E ++++++ +E E+ EQ + E+I
Sbjct: 407 EKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKI 466
Query: 112 CSEEERAKAKHLARQLEEKDRVLKKQDAFYKEQLARLEERSSEFYRVTTEQYQKAAEEV- 170
+E+R + + + EEK R +++ +E++ R EE+ E ++ E+ ++ EE+
Sbjct: 467 REQEKRQEQEAKMWRQEEKIREQEEKIREQEEKMWRQEEKIHEQEKIREEEKRQEQEEMW 526
Query: 171 --EAKFKRYE 178
E K + E
Sbjct: 527 RQEEKIREQE 536
Score = 35.0 bits (79), Expect = 0.053
Identities = 32/121 (26%), Positives = 63/121 (52%), Gaps = 10/121 (8%)
Query: 60 EELKRRVAEELALEQAKKESEDQKRLKQAKELDRERAAANEQLTRAILRE-RICSEEERA 118
+E K R EE+ ++ K +++K KQ +++ R+ ++Q + +E ++ +EE+
Sbjct: 528 QEEKIREQEEIWRQKEKIHEQEEKIRKQEEKMWRQEEKMHDQEEKIREQEEKVWRQEEKI 587
Query: 119 KAKH-LARQLEEKDRVLKKQDAFYKEQLARLEERSSEFYRVTTEQYQKAAEEVEAKFKRY 177
+ + R+ EEK +++Q+ +EQ EE+ E EQ +K E+ E K +R
Sbjct: 588 REQEEKIREQEEK---IREQEEMTQEQ----EEKMGEQEEKMCEQEEKMQEQ-EEKMRRQ 639
Query: 178 E 178
E
Sbjct: 640 E 640
Score = 34.3 bits (77), Expect = 0.090
Identities = 28/112 (25%), Positives = 53/112 (47%), Gaps = 2/112 (1%)
Query: 60 EELKRRVAEELALEQAKKESEDQKRLKQAKELDRERAAANEQLTRAILRERICSEEERAK 119
EE R E++ ++ K +++K +Q K + E+ E++ R E+I +EE +
Sbjct: 483 EEKIREQEEKIREQEEKMWRQEEKIHEQEKIREEEKRQEQEEMWRQ--EEKIREQEEIWR 540
Query: 120 AKHLARQLEEKDRVLKKQDAFYKEQLARLEERSSEFYRVTTEQYQKAAEEVE 171
K + EEK R +++ +E++ EE+ E Q +K E+ E
Sbjct: 541 QKEKIHEQEEKIRKQEEKMWRQEEKMHDQEEKIREQEEKVWRQEEKIREQEE 592
Score = 33.5 bits (75), Expect = 0.15
Identities = 27/120 (22%), Positives = 62/120 (51%), Gaps = 14/120 (11%)
Query: 60 EELKRRVAEELALEQAKKESEDQKRLKQAKELDRERAAANEQLTRAILRERICSEEERAK 119
EE R+ E++ ++ K +++K +Q +++ R+ EQ E+I +EE+ +
Sbjct: 549 EEKIRKQEEKMWRQEEKMHDQEEKIREQEEKVWRQEEKIREQ------EEKIREQEEKIR 602
Query: 120 -AKHLARQLEEK-----DRVLKKQDAF--YKEQLARLEERSSEFYRVTTEQYQKAAEEVE 171
+ + ++ EEK +++ ++++ +E++ R EE+ E + EQ +K E+ E
Sbjct: 603 EQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEE 662
>gi|239735592 TRAF2 and NCK interacting kinase isoform 8 [Homo
sapiens]
Length = 1268
Score = 43.5 bits (101), Expect = 1e-04
Identities = 35/123 (28%), Positives = 61/123 (49%), Gaps = 15/123 (12%)
Query: 70 LALEQAKKESEDQKRLKQAKELDRERAAANEQLTRAILRERICSEEERAKAKHLARQLEE 129
L L+ A KE + R +Q ++ RE NE+ R +L ER EE+ + + + +
Sbjct: 355 LRLQLANKERSEALRRQQLEQQQRE----NEEHKRQLLAERQKRIEEQKEQRRRLEEQQR 410
Query: 130 KDRVLKKQDA-----FYKEQLARLEER-----SSEFYRVTTEQYQKAAEEVEAKFKRYES 179
+++ L+KQ Y+EQ+ R EER E+ R E+ Q+ AE ++ + K+
Sbjct: 411 REKELRKQQEREQRRHYEEQMRREEERRRAEHEQEYKRKQLEE-QRQAERLQRQLKQERD 469
Query: 180 HPV 182
+ V
Sbjct: 470 YLV 472
Score = 38.1 bits (87), Expect = 0.006
Identities = 30/115 (26%), Positives = 60/115 (52%), Gaps = 7/115 (6%)
Query: 59 DEELKRRVAEELALEQAKKESEDQKRLKQAKELDRERAAANEQLTRAILRERICSEEERA 118
+EE KR++ E ++ +++ E ++RL++ + ++E E+ R E++ EEER
Sbjct: 380 NEEHKRQLLAERQ-KRIEEQKEQRRRLEEQQRREKELRKQQEREQRRHYEEQMRREEERR 438
Query: 119 KAKHLARQLEEKDRVLKKQDAFYKEQLARLEERSSEFYRVTTEQYQKAAEEVEAK 173
+A+H + E K + L++Q + Q +ER Y V+ + ++ VE K
Sbjct: 439 RAEH---EQEYKRKQLEEQRQAERLQRQLKQERD---YLVSLQHQRQEQRPVEKK 487
>gi|239735590 TRAF2 and NCK interacting kinase isoform 7 [Homo
sapiens]
Length = 1276
Score = 43.5 bits (101), Expect = 1e-04
Identities = 35/123 (28%), Positives = 61/123 (49%), Gaps = 15/123 (12%)
Query: 70 LALEQAKKESEDQKRLKQAKELDRERAAANEQLTRAILRERICSEEERAKAKHLARQLEE 129
L L+ A KE + R +Q ++ RE NE+ R +L ER EE+ + + + +
Sbjct: 355 LRLQLANKERSEALRRQQLEQQQRE----NEEHKRQLLAERQKRIEEQKEQRRRLEEQQR 410
Query: 130 KDRVLKKQDA-----FYKEQLARLEER-----SSEFYRVTTEQYQKAAEEVEAKFKRYES 179
+++ L+KQ Y+EQ+ R EER E+ R E+ Q+ AE ++ + K+
Sbjct: 411 REKELRKQQEREQRRHYEEQMRREEERRRAEHEQEYKRKQLEE-QRQAERLQRQLKQERD 469
Query: 180 HPV 182
+ V
Sbjct: 470 YLV 472
Score = 38.1 bits (87), Expect = 0.006
Identities = 30/115 (26%), Positives = 60/115 (52%), Gaps = 7/115 (6%)
Query: 59 DEELKRRVAEELALEQAKKESEDQKRLKQAKELDRERAAANEQLTRAILRERICSEEERA 118
+EE KR++ E ++ +++ E ++RL++ + ++E E+ R E++ EEER
Sbjct: 380 NEEHKRQLLAERQ-KRIEEQKEQRRRLEEQQRREKELRKQQEREQRRHYEEQMRREEERR 438
Query: 119 KAKHLARQLEEKDRVLKKQDAFYKEQLARLEERSSEFYRVTTEQYQKAAEEVEAK 173
+A+H + E K + L++Q + Q +ER Y V+ + ++ VE K
Sbjct: 439 RAEH---EQEYKRKQLEEQRQAERLQRQLKQERD---YLVSLQHQRQEQRPVEKK 487
>gi|239735584 TRAF2 and NCK interacting kinase isoform 4 [Homo
sapiens]
Length = 1323
Score = 43.5 bits (101), Expect = 1e-04
Identities = 35/123 (28%), Positives = 61/123 (49%), Gaps = 15/123 (12%)
Query: 70 LALEQAKKESEDQKRLKQAKELDRERAAANEQLTRAILRERICSEEERAKAKHLARQLEE 129
L L+ A KE + R +Q ++ RE NE+ R +L ER EE+ + + + +
Sbjct: 355 LRLQLANKERSEALRRQQLEQQQRE----NEEHKRQLLAERQKRIEEQKEQRRRLEEQQR 410
Query: 130 KDRVLKKQDA-----FYKEQLARLEER-----SSEFYRVTTEQYQKAAEEVEAKFKRYES 179
+++ L+KQ Y+EQ+ R EER E+ R E+ Q+ AE ++ + K+
Sbjct: 411 REKELRKQQEREQRRHYEEQMRREEERRRAEHEQEYKRKQLEE-QRQAERLQRQLKQERD 469
Query: 180 HPV 182
+ V
Sbjct: 470 YLV 472
Score = 38.1 bits (87), Expect = 0.006
Identities = 30/115 (26%), Positives = 60/115 (52%), Gaps = 7/115 (6%)
Query: 59 DEELKRRVAEELALEQAKKESEDQKRLKQAKELDRERAAANEQLTRAILRERICSEEERA 118
+EE KR++ E ++ +++ E ++RL++ + ++E E+ R E++ EEER
Sbjct: 380 NEEHKRQLLAERQ-KRIEEQKEQRRRLEEQQRREKELRKQQEREQRRHYEEQMRREEERR 438
Query: 119 KAKHLARQLEEKDRVLKKQDAFYKEQLARLEERSSEFYRVTTEQYQKAAEEVEAK 173
+A+H + E K + L++Q + Q +ER Y V+ + ++ VE K
Sbjct: 439 RAEH---EQEYKRKQLEEQRQAERLQRQLKQERD---YLVSLQHQRQEQRPVEKK 487
>gi|239735582 TRAF2 and NCK interacting kinase isoform 3 [Homo
sapiens]
Length = 1331
Score = 43.5 bits (101), Expect = 1e-04
Identities = 35/123 (28%), Positives = 61/123 (49%), Gaps = 15/123 (12%)
Query: 70 LALEQAKKESEDQKRLKQAKELDRERAAANEQLTRAILRERICSEEERAKAKHLARQLEE 129
L L+ A KE + R +Q ++ RE NE+ R +L ER EE+ + + + +
Sbjct: 355 LRLQLANKERSEALRRQQLEQQQRE----NEEHKRQLLAERQKRIEEQKEQRRRLEEQQR 410
Query: 130 KDRVLKKQDA-----FYKEQLARLEER-----SSEFYRVTTEQYQKAAEEVEAKFKRYES 179
+++ L+KQ Y+EQ+ R EER E+ R E+ Q+ AE ++ + K+
Sbjct: 411 REKELRKQQEREQRRHYEEQMRREEERRRAEHEQEYKRKQLEE-QRQAERLQRQLKQERD 469
Query: 180 HPV 182
+ V
Sbjct: 470 YLV 472
Score = 38.1 bits (87), Expect = 0.006
Identities = 30/115 (26%), Positives = 60/115 (52%), Gaps = 7/115 (6%)
Query: 59 DEELKRRVAEELALEQAKKESEDQKRLKQAKELDRERAAANEQLTRAILRERICSEEERA 118
+EE KR++ E ++ +++ E ++RL++ + ++E E+ R E++ EEER
Sbjct: 380 NEEHKRQLLAERQ-KRIEEQKEQRRRLEEQQRREKELRKQQEREQRRHYEEQMRREEERR 438
Query: 119 KAKHLARQLEEKDRVLKKQDAFYKEQLARLEERSSEFYRVTTEQYQKAAEEVEAK 173
+A+H + E K + L++Q + Q +ER Y V+ + ++ VE K
Sbjct: 439 RAEH---EQEYKRKQLEEQRQAERLQRQLKQERD---YLVSLQHQRQEQRPVEKK 487
>gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens]
Length = 2230
Score = 43.5 bits (101), Expect = 1e-04
Identities = 48/155 (30%), Positives = 83/155 (53%), Gaps = 28/155 (18%)
Query: 60 EELKRRVAEEL--ALEQAKKESEDQKRLK-----QAKELDR----ERAAANEQLTRAILR 108
E+ +R EEL AL A+K E +++LK Q K +++ ER + ++L+R + +
Sbjct: 406 EKSERAAFEELEKALSTAQKTEEARRKLKAEMDEQIKTIEKTSEEERISLQQELSR-VKQ 464
Query: 109 ERI-----CSEEERAKA-----KHLARQLEEKDRVLKKQDAFYKEQL-ARLEERSSEFYR 157
E + SEE+ AK K LAR+ +E + L+ ++ ++EQ+ LE+ SE+ +
Sbjct: 465 EVVDVMKKSSEEQIAKLQKLHEKELARKEQELTKKLQTREREFQEQMKVALEKSQSEYLK 524
Query: 158 VTTEQYQK---AAEEVEAKFKRY--ESHPVCADLQ 187
++ E+ Q+ A EE+E + K ES DLQ
Sbjct: 525 ISQEKEQQESLALEELELQKKAILTESENKLRDLQ 559
Score = 40.8 bits (94), Expect = 0.001
Identities = 35/150 (23%), Positives = 72/150 (48%), Gaps = 9/150 (6%)
Query: 60 EELKRRVAEELALEQAKKES---EDQKRLKQAKELDRERAAANEQLTRAILRERICSEEE 116
EE+ + E+L ++Q + ES E + LK +L+ E + +Q + +++ + ++ +
Sbjct: 669 EEMNEKTLEKLDVKQTELESLSSELSEVLKARHKLEEELSVLKDQTDK--MKQELEAKMD 726
Query: 117 RAKAKHLARQ---LEEKDRVLKKQDAFYKEQLARLEERSSEFYRVTTEQYQKAAEEVEAK 173
K H + ++E + +++ + K+Q+ +LE E + E +Q E +EA
Sbjct: 727 EQKNHHQQQVDSIIKEHEVSIQRTEKALKDQINQLELLLKERDKHLKE-HQAHVENLEAD 785
Query: 174 FKRYESHPVCADLQAKILQCYRENTHQTLK 203
KR E A + + Q Y+ TH+ K
Sbjct: 786 IKRSEGELQQASAKLDVFQSYQSATHEQTK 815
Score = 34.7 bits (78), Expect = 0.069
Identities = 36/168 (21%), Positives = 77/168 (45%), Gaps = 15/168 (8%)
Query: 60 EELKRRVAE--ELALEQAKKESEDQKRLKQAKELDRERAAANEQLTRAILRERICSEEER 117
E+LK++ A LA ++ K ++ +K + +E EQL ++ +EE++
Sbjct: 1113 EQLKQKSAHVNSLAQDETKLKAHLEKLEVDLNKSLKENTFLQEQLVEL----KMLAEEDK 1168
Query: 118 AKAKHLARQLEEKDRVLKKQDAFYKEQLARLEERSSEFYRVTTEQYQKAAEEVEAKFKRY 177
K L +L+ D + + +++ LE++S EF +++ E A +++ K+
Sbjct: 1169 RKVSELTSKLKTTDEEFQSLKSSHEKSNKSLEDKSLEFKKLSEE----LAIQLDICCKKT 1224
Query: 178 ESHPVCADLQAKILQCYRENTHQTLKCSALATQYMHCVNHAKQSMLEK 225
E A L+AK + ++ +T + + H K+++L K
Sbjct: 1225 E-----ALLEAKTNELINISSSKTNAILSRISHCQHRTTKVKEALLIK 1267
Score = 33.5 bits (75), Expect = 0.15
Identities = 29/129 (22%), Positives = 54/129 (41%), Gaps = 9/129 (6%)
Query: 60 EELKRRVAEELALEQAKKESEDQKRLKQAKELDRERAAANEQLTRAILRERICSEEE--- 116
+E + E++ EQ E + LKQ + A EQ ++E I +E
Sbjct: 1969 KEYDQEREEKIKQEQEDLELKHNSTLKQLMREFNTQLAQKEQELEMTIKETINKAQEVEA 2028
Query: 117 ------RAKAKHLARQLEEKDRVLKKQDAFYKEQLARLEERSSEFYRVTTEQYQKAAEEV 170
+ + L +++ EKD LK+ Y+E L EE + R Q ++ ++
Sbjct: 2029 ELLESHQEETNQLLKKIAEKDDDLKRTAKRYEEILDAREEEMTAKVRDLQTQLEELQKKY 2088
Query: 171 EAKFKRYES 179
+ K ++ E+
Sbjct: 2089 QQKLEQEEN 2097
Score = 31.6 bits (70), Expect = 0.58
Identities = 31/123 (25%), Positives = 60/123 (48%), Gaps = 14/123 (11%)
Query: 61 ELKRRVAEELALEQ---AKKESEDQKRLKQAKEL----DRERAAANEQLTRAILRERICS 113
E KR++ E L +++ A+ S ++ Q +EL ++ AA E+L +A+ + +
Sbjct: 368 ETKRQMHETLEMKEEEIAQLRSRIKQMTTQGEELREQKEKSERAAFEELEKALSTAQ-KT 426
Query: 114 EEERAKAKHLARQLEEKDRVLKKQDAFYKEQLARLEERSSEFYRVTTEQYQKAAEEVEAK 173
EE R K K E D +K + +E+ L++ S + + +K++EE AK
Sbjct: 427 EEARRKLK------AEMDEQIKTIEKTSEEERISLQQELSRVKQEVVDVMKKSSEEQIAK 480
Query: 174 FKR 176
++
Sbjct: 481 LQK 483
Score = 28.5 bits (62), Expect = 4.9
Identities = 27/109 (24%), Positives = 51/109 (46%), Gaps = 11/109 (10%)
Query: 60 EELKRRVAEELALEQAKKESEDQKRLKQAKELDRERAAANEQLTRAILRERICSEEERAK 119
EE RV E E+ E+Q +A+ +++ + L+ E + + E+R +
Sbjct: 1574 EEKDNRVKEA---EEKILTLENQVYSMKAELETKKKELEHVNLSVKSKEEELKALEDRLE 1630
Query: 120 AKHLARQLEEKDRVLKKQDAFYKEQLARLEERSSEFYRVTTEQYQKAAE 168
++ A+ E K + +K A K+ L+++EE+ EQY+K E
Sbjct: 1631 SESAAKLAELKRKAEQKIAAIKKQLLSQMEEKE--------EQYKKGTE 1671
>gi|22758136 MAP7 domain containing 2 [Homo sapiens]
Length = 732
Score = 43.5 bits (101), Expect = 1e-04
Identities = 49/177 (27%), Positives = 89/177 (50%), Gaps = 17/177 (9%)
Query: 28 LSENVIDRM---KESSPSGSKSQRYSGAYG---ASVSDE-ELKRRVAEELALEQAKKESE 80
L ++V+D+ K ++ +G K++ S A G A +D E + +AE+ + +KE E
Sbjct: 360 LEKHVVDKHASEKHAAAAGGKAEN-SAALGKPTAGTTDAGEAAKILAEKRRQARLQKEQE 418
Query: 81 DQKRLKQAKELDRERAAANEQLTRAILRERICSEEE-RAKAKHLARQLEEKDRVLKKQDA 139
+Q+R+++ ++ ER E+L R ER+ EEE R + + RQ EEK KKQ+
Sbjct: 419 EQERVEKEEQDRLER----EELKRKAEEERLRLEEEARKQEEERKRQEEEK----KKQEG 470
Query: 140 FYKEQLARLEERSSEFYRVTTEQYQKAAEEVEAKFKRYESHPVCADLQAKILQCYRE 196
K + +R +E + E+ ++ +E K+ E+ A A+ ++ RE
Sbjct: 471 EEKRKAGEEAKRKAEEELLLKEKQEQEKQEKAMIEKQKEAAETKAREVAEQMRLERE 527
Score = 40.0 bits (92), Expect = 0.002
Identities = 32/132 (24%), Positives = 64/132 (48%), Gaps = 3/132 (2%)
Query: 9 RVTFEADENENITVVKGIRLSENVIDRMKESSPSGSKSQRYSGAYGASVSDEELKRRVAE 68
R+ E +E E + + RL + R E + + +EE K++ E
Sbjct: 412 RLQKEQEEQERVEKEEQDRLEREELKRKAEEERLRLEEEARKQEEERKRQEEEKKKQEGE 471
Query: 69 EL--ALEQAKKESEDQKRLKQAKELDR-ERAAANEQLTRAILRERICSEEERAKAKHLAR 125
E A E+AK+++E++ LK+ +E ++ E+A +Q A + R +E+ R + + +
Sbjct: 472 EKRKAGEEAKRKAEEELLLKEKQEQEKQEKAMIEKQKEAAETKAREVAEQMRLEREQIML 531
Query: 126 QLEEKDRVLKKQ 137
Q+E++ KK+
Sbjct: 532 QIEQERLERKKR 543
Score = 32.7 bits (73), Expect = 0.26
Identities = 28/124 (22%), Positives = 56/124 (45%), Gaps = 7/124 (5%)
Query: 13 EADENENITVVKGIRLSENVIDRMKESSPSGSKSQRYSGAYGASVSDEELKRRVAEELAL 72
E +E + + +RL E + +E + ++ G EE KR+ EEL L
Sbjct: 432 EREELKRKAEEERLRLEEEARKQEEERKRQEEEKKKQEGEEKRKAG-EEAKRKAEEELLL 490
Query: 73 EQAKKESEDQKRL----KQAKELDRERAAANEQLTRAILRERICSEEERAKAKHLARQLE 128
++ +++ + +K + K+A E A +L R + +I E+ER + K ++
Sbjct: 491 KEKQEQEKQEKAMIEKQKEAAETKAREVAEQMRLEREQIMLQI--EQERLERKKRIDEIM 548
Query: 129 EKDR 132
++ R
Sbjct: 549 KRTR 552
Score = 32.0 bits (71), Expect = 0.45
Identities = 20/87 (22%), Positives = 50/87 (57%), Gaps = 8/87 (9%)
Query: 78 ESEDQKRLKQAKELDRERAAANEQLTRAILRERICSEEERAKAKHLARQLEEKDRVLKKQ 137
+S++++RL + + +RE+ A + ++I +++RA+ ++ +Q+EE+ R L++Q
Sbjct: 50 KSDERQRLAKERREEREKCLAARE-------QQILEKQKRARLQY-EKQMEERWRKLEEQ 101
Query: 138 DAFYKEQLARLEERSSEFYRVTTEQYQ 164
++ A +EE+ + R E+ +
Sbjct: 102 RQREDQKRAAVEEKRKQKLREEEERLE 128
Score = 27.7 bits (60), Expect = 8.4
Identities = 23/105 (21%), Positives = 55/105 (52%), Gaps = 12/105 (11%)
Query: 34 DRMKESSPSGSKSQRYSGAYGASVSDEELKRRVAEELALEQAKKESEDQKRLKQAKELDR 93
+R + + + ++ A + +++ + R+ E +E+ ++ E+Q++ + D+
Sbjct: 53 ERQRLAKERREEREKCLAAREQQILEKQKRARLQYEKQMEERWRKLEEQRQRE-----DQ 107
Query: 94 ERAAANEQLTRAILRERICSEEERAKAKHLARQLEEKDRV-LKKQ 137
+RAA E+ ++++ EEER +A + R LE ++ LKK+
Sbjct: 108 KRAAVEEK-----RKQKLREEEERLEAM-MRRSLERTQQLELKKK 146
Score = 27.7 bits (60), Expect = 8.4
Identities = 32/109 (29%), Positives = 53/109 (48%), Gaps = 18/109 (16%)
Query: 60 EELKRRVAEE-LALEQA---------KKESEDQKRLKQAKELDRERA--AANEQL----- 102
EELKR+ EE L LE+ ++E E +K+ + K E A A E+L
Sbjct: 434 EELKRKAEEERLRLEEEARKQEEERKRQEEEKKKQEGEEKRKAGEEAKRKAEEELLLKEK 493
Query: 103 TRAILRERICSEEERAKAKHLARQLEEKDRVLKKQDAFYKEQLARLEER 151
+E+ E+++ A+ AR++ E+ R+ ++Q EQ RLE +
Sbjct: 494 QEQEKQEKAMIEKQKEAAETKAREVAEQMRLEREQIMLQIEQ-ERLERK 541
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.310 0.124 0.327
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 7,537,145
Number of Sequences: 37866
Number of extensions: 323538
Number of successful extensions: 5488
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 265
Number of HSP's successfully gapped in prelim test: 624
Number of HSP's that attempted gapping in prelim test: 2600
Number of HSP's gapped (non-prelim): 2430
length of query: 227
length of database: 18,247,518
effective HSP length: 99
effective length of query: 128
effective length of database: 14,498,784
effective search space: 1855844352
effective search space used: 1855844352
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 60 (27.7 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.