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Search of human proteins with 14149902
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|14149902 hypothetical protein LOC84167 [Homo sapiens]
(657 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|14149902 hypothetical protein LOC84167 [Homo sapiens] 1264 0.0
gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens] 60 8e-09
gi|207113164 Treacher Collins-Franceschetti syndrome 1 isoform f... 54 6e-07
gi|207113162 Treacher Collins-Franceschetti syndrome 1 isoform e... 54 6e-07
gi|207113160 Treacher Collins-Franceschetti syndrome 1 isoform d... 54 6e-07
gi|57164975 Treacher Collins-Franceschetti syndrome 1 isoform b ... 54 6e-07
gi|57164977 Treacher Collins-Franceschetti syndrome 1 isoform a ... 54 6e-07
gi|55741473 HECT, C2 and WW domain containing E3 ubiquitin prote... 50 5e-06
gi|167736355 mucin 4 isoform a [Homo sapiens] 50 9e-06
gi|195976782 Paf1/RNA polymerase II complex component [Homo sapi... 50 9e-06
gi|239758038 PREDICTED: mucin 3A, cell surface associated, parti... 49 1e-05
gi|57164979 Treacher Collins-Franceschetti syndrome 1 isoform c ... 49 1e-05
gi|239758058 PREDICTED: similar to mucin, partial [Homo sapiens] 49 2e-05
gi|217330641 IWS1 homolog [Homo sapiens] 48 3e-05
gi|34482047 adaptor-related protein complex 3, beta 2 subunit [H... 47 6e-05
gi|8923040 CDKN2A interacting protein [Homo sapiens] 45 2e-04
gi|153945728 microtubule-associated protein 1B [Homo sapiens] 45 2e-04
gi|22749117 hypothetical protein LOC152405 [Homo sapiens] 45 3e-04
gi|239752529 PREDICTED: similar to mucin [Homo sapiens] 44 4e-04
gi|239740827 PREDICTED: hypothetical protein XP_002344067 [Homo ... 43 8e-04
gi|148596949 nucleolar and coiled-body phosphoprotein 1 [Homo sa... 43 0.001
gi|4758172 dentin matrix acidic phosphoprotein 1 isoform 1 precu... 42 0.002
gi|121256621 dentin matrix acidic phosphoprotein 1 isoform 2 pre... 42 0.002
gi|239754269 PREDICTED: hypothetical protein [Homo sapiens] 42 0.002
gi|169168665 PREDICTED: hypothetical protein [Homo sapiens] 42 0.002
gi|113417486 PREDICTED: hypothetical protein [Homo sapiens] 42 0.002
gi|239740898 PREDICTED: hypothetical protein [Homo sapiens] 42 0.002
gi|239740777 PREDICTED: hypothetical protein [Homo sapiens] 42 0.002
gi|239740724 PREDICTED: hypothetical protein [Homo sapiens] 42 0.002
gi|239740674 PREDICTED: hypothetical protein [Homo sapiens] 42 0.002
>gi|14149902 hypothetical protein LOC84167 [Homo sapiens]
Length = 657
Score = 1264 bits (3272), Expect = 0.0
Identities = 657/657 (100%), Positives = 657/657 (100%)
Query: 1 MASARKASRPMRDVFGDFSDVSLEDSTMEEIRNFQISRNLTKIAPGHSRFLKRNQTLDEK 60
MASARKASRPMRDVFGDFSDVSLEDSTMEEIRNFQISRNLTKIAPGHSRFLKRNQTLDEK
Sbjct: 1 MASARKASRPMRDVFGDFSDVSLEDSTMEEIRNFQISRNLTKIAPGHSRFLKRNQTLDEK 60
Query: 61 HLLLKENPVLGSGPRLASCRPPTTASRIRANAALMKLAQLETRIMNRKLQRNLSDTESDS 120
HLLLKENPVLGSGPRLASCRPPTTASRIRANAALMKLAQLETRIMNRKLQRNLSDTESDS
Sbjct: 61 HLLLKENPVLGSGPRLASCRPPTTASRIRANAALMKLAQLETRIMNRKLQRNLSDTESDS 120
Query: 121 MTADAGLPKRADRILSGGALELASQNTDKTSQNQARELPVTENNAQNAKVSRFLKKKQAP 180
MTADAGLPKRADRILSGGALELASQNTDKTSQNQARELPVTENNAQNAKVSRFLKKKQAP
Sbjct: 121 MTADAGLPKRADRILSGGALELASQNTDKTSQNQARELPVTENNAQNAKVSRFLKKKQAP 180
Query: 181 VENISPEAPAGKERTLQTPKQKEPARTFDSPDSDEEEMKVLLGSLMDSSREKNTNQGFSS 240
VENISPEAPAGKERTLQTPKQKEPARTFDSPDSDEEEMKVLLGSLMDSSREKNTNQGFSS
Sbjct: 181 VENISPEAPAGKERTLQTPKQKEPARTFDSPDSDEEEMKVLLGSLMDSSREKNTNQGFSS 240
Query: 241 ANVSEEEERKLFSVPSQLRAFTVPSVELSSAKPSQTSHLPTSLAADRTLHSTRSRADYPQ 300
ANVSEEEERKLFSVPSQLRAFTVPSVELSSAKPSQTSHLPTSLAADRTLHSTRSRADYPQ
Sbjct: 241 ANVSEEEERKLFSVPSQLRAFTVPSVELSSAKPSQTSHLPTSLAADRTLHSTRSRADYPQ 300
Query: 301 SHVSSDTASHTPSVSITGAFSNSVSLKMGHVKLVSSPGRSEAETVDEPVSEGADDSLDEF 360
SHVSSDTASHTPSVSITGAFSNSVSLKMGHVKLVSSPGRSEAETVDEPVSEGADDSLDEF
Sbjct: 301 SHVSSDTASHTPSVSITGAFSNSVSLKMGHVKLVSSPGRSEAETVDEPVSEGADDSLDEF 360
Query: 361 RINILSLDGLAPAVSENSDLEQEEESAQRQKTAGKIFRAEASTGQDAPRQAQARSWASQG 420
RINILSLDGLAPAVSENSDLEQEEESAQRQKTAGKIFRAEASTGQDAPRQAQARSWASQG
Sbjct: 361 RINILSLDGLAPAVSENSDLEQEEESAQRQKTAGKIFRAEASTGQDAPRQAQARSWASQG 420
Query: 421 KAASAEGDESEVSEHLSASSASAIQQDSTSSMQPPSEAPMVNTVSSAYSEDFENSPSLTA 480
KAASAEGDESEVSEHLSASSASAIQQDSTSSMQPPSEAPMVNTVSSAYSEDFENSPSLTA
Sbjct: 421 KAASAEGDESEVSEHLSASSASAIQQDSTSSMQPPSEAPMVNTVSSAYSEDFENSPSLTA 480
Query: 481 SEPTAHSKESLDRTLDALSESSSSVKTDLPQTAESRKKSGRHVTRVLVKDTAVQTPDPAF 540
SEPTAHSKESLDRTLDALSESSSSVKTDLPQTAESRKKSGRHVTRVLVKDTAVQTPDPAF
Sbjct: 481 SEPTAHSKESLDRTLDALSESSSSVKTDLPQTAESRKKSGRHVTRVLVKDTAVQTPDPAF 540
Query: 541 TYEWTKVASMAAMGPALGGAYVDPTPIANHVISADAIEALTAYSPAVLALHDVLKQQLSL 600
TYEWTKVASMAAMGPALGGAYVDPTPIANHVISADAIEALTAYSPAVLALHDVLKQQLSL
Sbjct: 541 TYEWTKVASMAAMGPALGGAYVDPTPIANHVISADAIEALTAYSPAVLALHDVLKQQLSL 600
Query: 601 TQQFIQASRHLHASLLRSLDADSFHYHTLEEAKEYIRCHRPAPLTMEDALEEVNKEL 657
TQQFIQASRHLHASLLRSLDADSFHYHTLEEAKEYIRCHRPAPLTMEDALEEVNKEL
Sbjct: 601 TQQFIQASRHLHASLLRSLDADSFHYHTLEEAKEYIRCHRPAPLTMEDALEEVNKEL 657
>gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens]
Length = 1301
Score = 59.7 bits (143), Expect = 8e-09
Identities = 80/415 (19%), Positives = 168/415 (40%), Gaps = 31/415 (7%)
Query: 114 SDTESDSMTADAGLPKRADRILSGGALELASQNTDKTSQNQARELPVTENNAQNAKVSRF 173
S++ SDS ++D+ +D S +S ++D + + + + + +++ + S
Sbjct: 574 SNSSSDSDSSDSDSSDSSDSDSSD-----SSNSSDSSDSSDSSDSSDSSDSSDSKSDSSK 628
Query: 174 LKKKQAPVENISPEAPAGKERTLQTPKQKEPARTFDSPDSDEEEMKVLLGSLMDSSREKN 233
+ + ++ S + + + + + + +S DS + S DSS +
Sbjct: 629 SESDSSDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSSSSSDSSNSSD 688
Query: 234 TNQGFSSANVSEEEERKLFSVPSQLRAFTVPSVELSSAKPSQTSHLPTSLAADRTLHSTR 293
++ S+N SE + S + S + S +S S ++D ++
Sbjct: 689 SSDSSDSSNSSESSD----------------SSDSSDSDSSDSSDSSNSNSSDSDSSNSS 732
Query: 294 SRADYPQSHVSSDTA--SHTPSVSITGAFSNSVSLKMGHVKLVSSPGRSEAETVDEPVSE 351
+D S SSD++ S++ S + SNS SS + +++ D S
Sbjct: 733 DSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSS 792
Query: 352 GADDSLDEFRINILS-----LDGLAPAVSENSDLEQEEESAQRQKTAGKIFRAEASTGQD 406
+ DS + + S D S +SD +S+ ++ +++S G D
Sbjct: 793 DSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSD 852
Query: 407 APRQAQARSWASQGKAASAEGDESEVSEHLSASSASAIQQDSTSSMQPPSEAPMVNTVSS 466
+ ++ S S + S++ S S S S+ S+ DS+ S S++ ++ +S
Sbjct: 853 SDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNESSNSSDSSDSSN-SSDSDSSDSSNS 911
Query: 467 AYSEDFENSPSLTASEPTAHSKESLD--RTLDALSESSSSVKTDLPQTAESRKKS 519
+ S D NS + S ++ + S D + D+ S SS +D +++S S
Sbjct: 912 SDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSS 966
Score = 58.9 bits (141), Expect = 1e-08
Identities = 77/394 (19%), Positives = 156/394 (39%), Gaps = 15/394 (3%)
Query: 114 SDTESDSMTADAGLPKRADRILSGGALELASQNTDKTSQNQARELPVTENNAQNAKVSRF 173
S SDS ++D+ + + +S ++D ++ + + + +++ ++ S
Sbjct: 897 SSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSD- 955
Query: 174 LKKKQAPVENISPEAPAGKERTLQTPKQKEPARTFDSPDSDEEEMKVLLGSLMDSSREKN 233
+ N S + + + + + + + DS DS + DSS +
Sbjct: 956 -SSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSD 1014
Query: 234 TNQGFSSANVSEEEERKLFSVPSQLRAFTVPSVELSSAKPSQTSHLPTSLAADRTLHSTR 293
++ S+N S+ S S + S S+ S +S S + + S+
Sbjct: 1015 SSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSD 1074
Query: 294 SRADYPQSHVSSDTASHTPSVSITGAFSNSVSLKMGHVKLVSSPGRSEAETVDEPVSEGA 353
S +D S SSD++ + S + + +S S SS +++ D S +
Sbjct: 1075 S-SDSSDSSESSDSSDSSNSSDSSDSSDSSDSSD-------SSDSSDSSDSSDSSNSSDS 1126
Query: 354 DDSLDEFRINILSLDGLAPAVSENSDLEQEEESAQRQKTAGKIFRAEASTGQDAPRQAQA 413
DS D + S + SE+SD +S+ ++ +++S D+ + +
Sbjct: 1127 SDSSDSSDSSDSSNSSDSSDSSESSDSSDSSDSSDSSDSSDS---SDSSDSSDSSNSSDS 1183
Query: 414 RSWASQGKAASAEGDESEVSEHLSASSASAIQQDSTSSMQPPSEAPMVNTVSSAYSEDFE 473
S + S++ +S S S SS S+ DS+ S + ++ S+ S D
Sbjct: 1184 SD--SSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSNESSDSSDSS 1241
Query: 474 NSPSLTASEPTAHSKESLDRTLDALSESSSSVKT 507
+S + S ++ S +S D T D+ ES S K+
Sbjct: 1242 DSSDSSNSSDSSDSSDSSDSTSDSNDESDSQSKS 1275
Score = 57.8 bits (138), Expect = 3e-08
Identities = 73/409 (17%), Positives = 158/409 (38%), Gaps = 13/409 (3%)
Query: 114 SDTESDSMTADAGLPKRADRILSGGALELASQNTDKTSQNQARELPVTENNAQNAKVSRF 173
SD+ S ++D+ + +S ++D + + + + +N+ ++ S
Sbjct: 672 SDSSDSSSSSDSSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNS 731
Query: 174 LKKKQAPVENISPEAPAGKERTLQTPKQKEPARTFDSPDSDEEEMKVLLGSLMDSSREKN 233
+ + S ++ + + + + + + DS DS + DSS N
Sbjct: 732 SDSSDSSNSSDSSDS-SDSSNSSDSSDSSDSSNSSDSSDSSDSS---------DSSDSSN 781
Query: 234 TNQGFSSANVSEEEERKLFSVPSQLRAFTVPSVELSSAKPSQTSHLPTSLAADRTLHSTR 293
++ S+N S+ + S S + S S + + +S ++D + S
Sbjct: 782 SSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDS 841
Query: 294 SRADYPQSHVSSDTASHTPSVSITGAFSNSVSLKMGHVKLVSSPGRSEAETVDEPVSEGA 353
S + SD+++ + S + + + +S S S S + S +
Sbjct: 842 SDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNESSNSSDSSDSSNSS 901
Query: 354 D-DSLDEFRINILSLDGLAPAVSENSDLEQEEESAQRQKTAGKIFRAEASTGQDAPRQAQ 412
D DS D + S + SE+S+ S+ ++ +++S D+ +
Sbjct: 902 DSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSD 961
Query: 413 ARSWASQGKAASAEGDESEVSEHLSASSASAIQQDSTSSMQPPSEAPMVNTVSSAYSEDF 472
+ + + + S++ +S S S SS S+ DS+ S + ++ S+ S D
Sbjct: 962 SSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDS 1021
Query: 473 ENSPSLTASEPTAHSKESLDR--TLDALSESSSSVKTDLPQTAESRKKS 519
NS + S ++ S +S D + D+ S SS +D +++S S
Sbjct: 1022 SNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSS 1070
Score = 50.4 bits (119), Expect = 5e-06
Identities = 49/217 (22%), Positives = 101/217 (46%), Gaps = 11/217 (5%)
Query: 305 SDTASHTPSVSITGAFSNSVSLKMGHVKLVSSPGRSEAETVDEPVSEGADDSLDEFRINI 364
SD+ S T + G +N + K S G+S++ D S + DS D +
Sbjct: 515 SDSTSDTNNSDSNGNGNNGND---DNDKSDSGKGKSDSSDSDSSDSSNSSDSSDSSDSD- 570
Query: 365 LSLDGLAPAVSENSDLE----QEEESAQRQKTAGKIFRAEASTGQDAPRQAQARSWASQG 420
S D + + S++SD + + +S+ ++ +++S D+ + ++S +S+
Sbjct: 571 -SSDSNSSSDSDSSDSDSSDSSDSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSKSDSSKS 629
Query: 421 KAASAEGDESEVS--EHLSASSASAIQQDSTSSMQPPSEAPMVNTVSSAYSEDFENSPSL 478
++ S++ D S + S SS ++ DS++S + ++ S+ S D NS
Sbjct: 630 ESDSSDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSSSSSDSSNSSDS 689
Query: 479 TASEPTAHSKESLDRTLDALSESSSSVKTDLPQTAES 515
+ S +++S ES D + + S+SS S + +++S
Sbjct: 690 SDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDS 726
Score = 34.3 bits (77), Expect = 0.37
Identities = 38/172 (22%), Positives = 73/172 (42%), Gaps = 20/172 (11%)
Query: 350 SEGADDSLDEFRINILSLDGLAPAVSENSDLEQEEESAQRQKTAGKIFRAEASTGQDAPR 409
S+GA+D D + + + NSD + G ++ +G+
Sbjct: 507 SKGAEDD-----------DSDSTSDTNNSD-------SNGNGNNGNDDNDKSDSGKGKSD 548
Query: 410 QAQARSWASQGKAASAEGDESEVSEHLSASSASAIQQDSTSSMQPPSEAPMVNTVSSAYS 469
+ + S S + S++ +S+ S+ S+S + + DS+ S S ++ SS S
Sbjct: 549 SSDSDSSDSSNSSDSSDSSDSDSSDSNSSSDSDSSDSDSSDSSDSDSSDSSNSSDSSDSS 608
Query: 470 EDFENSPSLTASEPTAHS--KESLDRTLDALSESSSSVKTDLPQTAESRKKS 519
+ ++S S +S+ + S ES D+ S+SS S +D ++S S
Sbjct: 609 DSSDSSDSSDSSDSKSDSSKSESDSSDSDSKSDSSDSNSSDSSDNSDSSDSS 660
>gi|207113164 Treacher Collins-Franceschetti syndrome 1 isoform f
[Homo sapiens]
Length = 1412
Score = 53.5 bits (127), Expect = 6e-07
Identities = 88/429 (20%), Positives = 160/429 (37%), Gaps = 59/429 (13%)
Query: 108 KLQRNLSDTESDSMTADAGLPKRADRILSGGALELASQNTDKTSQNQARELPVTENNAQN 167
K ++ + ++ES ++D+ + A ++ A+Q Q + P N +
Sbjct: 523 KAEKPMDNSESSEESSDSADSEEAPAAMT------AAQAKPALKIPQTKACPKKTNTTAS 576
Query: 168 AKVSRFLKKKQAPVENISPEAPAGKERTLQTPKQKEPARTFDSPDSDEEEMKVLLGSLMD 227
AKV+ QAP + + +PAG + Q+ + S +SD EE K L +
Sbjct: 577 AKVAPVRVGTQAPRKAGTATSPAGSSPAVAGGTQRPAEDSSSSEESDSEEEKTGLAVTVG 636
Query: 228 SSREKNTNQGFSSANVSEEEERKLFSVPSQLRAFTVPSVELSSAKPSQTSHLPTSLAADR 287
++ +A+V V L T P + P +T T + A++
Sbjct: 637 QAKSVGKGLQVKAASV---------PVKGSLGQGTAPVL------PGKTGPTVTQVKAEK 681
Query: 288 TLHSTRSRADYPQSHVSSDTASHTPSVSITGAFSNSVSLKMGHVK-LVSSPGR---SEAE 343
S S + ++ A SV T A +N + + K +S+PG+ + A+
Sbjct: 682 QEDSESSEEESDSEEAAASPAQVKTSVKKTQAKANPAAARAPSAKGTISAPGKVVTAAAQ 741
Query: 344 TVDEPVSEGADDSLDEFRINIL-----SLDGLAPAVS-----------------ENSDLE 381
S+ + +L S+ + AV+ E SD E
Sbjct: 742 AKQRSPSKVKPPVRNPQNSTVLARGPASVPSVGKAVATAAQAQTGPEEDSGSSEEESDSE 801
Query: 382 QEEESAQRQKTAGKI--FRAEASTGQDAPRQAQARSWASQ-GKAASAEG---DESEVSEH 435
+E E+ + K +GK RA + +++PR+ A + + G +A+ G D SE
Sbjct: 802 EEAETLAQVKPSGKTHQIRAALAPAKESPRKGAAPTPPGKTGPSAAQAGKQDDSGSSSEE 861
Query: 436 LSASSASAIQQDSTSSMQP------PSEAPMVNTVSSAYSEDFENSPSLTASEPTAHSKE 489
+ + S ++P P+ +P + A ++ ASE TA S
Sbjct: 862 SDSDGEAPAAVTSAQVIKPPLIFVDPNRSPAGPAATPAQAQAASTPRKARASESTARSSS 921
Query: 490 SLDRTLDAL 498
S D +
Sbjct: 922 SESEDEDVI 930
Score = 41.2 bits (95), Expect = 0.003
Identities = 75/332 (22%), Positives = 126/332 (37%), Gaps = 41/332 (12%)
Query: 122 TADAGLPKRADRILSGGALELASQNTDKTSQNQARELPVTENNAQNAKVSRFLKKKQAPV 181
T++ G ++A+ + A + + TS++ E E A+ AK + L + V
Sbjct: 56 TSELGRKRKAEEDAALQAKKTRVSDPISTSESSEEE---EEAEAETAKATPRLASTNSSV 112
Query: 182 ENISPEAPAGKERTLQTPKQKEPARTFDSPDSDEEEMKVLLGSLMDSSREKNTNQGFSSA 241
+ ++ +T K + + P + + +L G S E + N +
Sbjct: 113 LGADLPSSMKEKAKAETEKAGKTGNSMPHPATGKTVANLLSGKSPRKSAEPSAN----TT 168
Query: 242 NVSEEEERKLFSVPSQLRAFTVPSVELSSAKPSQTSHLPTSLAADRTLHSTRSRADYPQS 301
VSE EE SVP+ A P + SA + +S TS ++D T ++ Q
Sbjct: 169 LVSETEEEG--SVPA-FGAAAKPG--MVSAGQADSSSEDTSSSSDETDVEVKASEKILQV 223
Query: 302 HVSSDTASHTPSVSITGAFSNSVSLKMGHVKLVSSPGRSEAETVDEPVSEGADDSLDEFR 361
+S A TP T A K G V + G+ E ++ E SE + DS +E
Sbjct: 224 RAASAPAKGTPGKGATPAPPG----KAGAVASQTKAGKPEEDS--ESSSEESSDSEEETP 277
Query: 362 INILSLD-----------------------GLAPAVSENSDLEQEEESAQRQKTAGKIFR 398
L G APA + + A +++ +
Sbjct: 278 AAKALLQAKASGKTSQVGAASAPAKESPRKGAAPAPPGKTGPAVAKAQAGKREEDSQSSS 337
Query: 399 AEASTGQDAPRQAQARSWASQGKAASAEGDES 430
E+ + ++AP QA+ A Q +AASA ES
Sbjct: 338 EESDSEEEAPAQAKPSGKAPQVRAASAPAKES 369
Score = 37.7 bits (86), Expect = 0.034
Identities = 71/371 (19%), Positives = 138/371 (37%), Gaps = 32/371 (8%)
Query: 124 DAGLPKRADRILSGGALELASQNTDKTSQNQARELP---VTENNAQNAKVSRFLKKK-QA 179
DA L + R+ + +S+ ++ A+ P T ++ A + +K+K +A
Sbjct: 68 DAALQAKKTRVSDPISTSESSEEEEEAEAETAKATPRLASTNSSVLGADLPSSMKEKAKA 127
Query: 180 PVE------NISPEAPAGKE----RTLQTP-KQKEPARTFDSPDSDEEEMKV------LL 222
E N P GK + ++P K EP+ EEE V
Sbjct: 128 ETEKAGKTGNSMPHPATGKTVANLLSGKSPRKSAEPSANTTLVSETEEEGSVPAFGAAAK 187
Query: 223 GSLMDSSREKNTNQGFSSANVSEEEERKLFSVPSQLRAFTVPSVELSSAKPSQTSHLPTS 282
++ + + ++++ SS++ + E K Q+RA + P+ +
Sbjct: 188 PGMVSAGQADSSSEDTSSSSDETDVEVKASEKILQVRAASAPAKGTPGKGATPAPPGKAG 247
Query: 283 LAADRTLHSTRSRADYPQSHVSSDTASHTPSVSITGAFSNSVSLKMGHVKLVSSPGRSEA 342
A +T S SSD+ TP+ S K V S+P +
Sbjct: 248 AVASQTKAGKPEEDSESSSEESSDSEEETPAAK--ALLQAKASGKTSQVGAASAPAKESP 305
Query: 343 ETVDEPVSEG-ADDSLDEFRINILSLDGLAPAVSENSDLEQEEESAQRQKTAGKIFRAEA 401
P G ++ + + D + + SE SD E+E + + RA +
Sbjct: 306 RKGAAPAPPGKTGPAVAKAQAGKREED--SQSSSEESDSEEEAPAQAKPSGKAPQVRAAS 363
Query: 402 STGQDAPRQAQARSWASQGKAASA------EGDESEVSEHLSASSASAIQQDSTSSMQPP 455
+ +++PR+ A + + A+A + ++S S S S A+ + + ++P
Sbjct: 364 APAKESPRKGAAPAPPRKTGPAAAQVQVGKQEEDSRSSSEESDSDREALAAMNAAQVKPL 423
Query: 456 SEAPMVNTVSS 466
++P V S+
Sbjct: 424 GKSPQVKPAST 434
>gi|207113162 Treacher Collins-Franceschetti syndrome 1 isoform e
[Homo sapiens]
Length = 1451
Score = 53.5 bits (127), Expect = 6e-07
Identities = 88/429 (20%), Positives = 160/429 (37%), Gaps = 59/429 (13%)
Query: 108 KLQRNLSDTESDSMTADAGLPKRADRILSGGALELASQNTDKTSQNQARELPVTENNAQN 167
K ++ + ++ES ++D+ + A ++ A+Q Q + P N +
Sbjct: 600 KAEKPMDNSESSEESSDSADSEEAPAAMT------AAQAKPALKIPQTKACPKKTNTTAS 653
Query: 168 AKVSRFLKKKQAPVENISPEAPAGKERTLQTPKQKEPARTFDSPDSDEEEMKVLLGSLMD 227
AKV+ QAP + + +PAG + Q+ + S +SD EE K L +
Sbjct: 654 AKVAPVRVGTQAPRKAGTATSPAGSSPAVAGGTQRPAEDSSSSEESDSEEEKTGLAVTVG 713
Query: 228 SSREKNTNQGFSSANVSEEEERKLFSVPSQLRAFTVPSVELSSAKPSQTSHLPTSLAADR 287
++ +A+V V L T P + P +T T + A++
Sbjct: 714 QAKSVGKGLQVKAASV---------PVKGSLGQGTAPVL------PGKTGPTVTQVKAEK 758
Query: 288 TLHSTRSRADYPQSHVSSDTASHTPSVSITGAFSNSVSLKMGHVK-LVSSPGR---SEAE 343
S S + ++ A SV T A +N + + K +S+PG+ + A+
Sbjct: 759 QEDSESSEEESDSEEAAASPAQVKTSVKKTQAKANPAAARAPSAKGTISAPGKVVTAAAQ 818
Query: 344 TVDEPVSEGADDSLDEFRINIL-----SLDGLAPAVS-----------------ENSDLE 381
S+ + +L S+ + AV+ E SD E
Sbjct: 819 AKQRSPSKVKPPVRNPQNSTVLARGPASVPSVGKAVATAAQAQTGPEEDSGSSEEESDSE 878
Query: 382 QEEESAQRQKTAGKI--FRAEASTGQDAPRQAQARSWASQ-GKAASAEG---DESEVSEH 435
+E E+ + K +GK RA + +++PR+ A + + G +A+ G D SE
Sbjct: 879 EEAETLAQVKPSGKTHQIRAALAPAKESPRKGAAPTPPGKTGPSAAQAGKQDDSGSSSEE 938
Query: 436 LSASSASAIQQDSTSSMQP------PSEAPMVNTVSSAYSEDFENSPSLTASEPTAHSKE 489
+ + S ++P P+ +P + A ++ ASE TA S
Sbjct: 939 SDSDGEAPAAVTSAQVIKPPLIFVDPNRSPAGPAATPAQAQAASTPRKARASESTARSSS 998
Query: 490 SLDRTLDAL 498
S D +
Sbjct: 999 SESEDEDVI 1007
Score = 39.7 bits (91), Expect = 0.009
Identities = 74/365 (20%), Positives = 141/365 (38%), Gaps = 34/365 (9%)
Query: 113 LSDTESDSMTADAGLPKRADRILSGGALELASQNTDKTSQNQARELPVTENNAQNAKVSR 172
+S+TE + G + + S G + +S++T +S E + AQ S
Sbjct: 170 VSETEEEGSVPAFGAAAKPGMV-SAGQADSSSEDTSSSSDETDVEGKPSVKPAQVKASS- 227
Query: 173 FLKKKQAPVENISPEAPAGKERTLQTPKQK----EPARTFDSPDSDEEEMKVLLGSLMDS 228
+ K++P +P AP GK + TP+ K PA+ P+ + E S S
Sbjct: 228 -VSTKESPARKAAP-AP-GKVGDV-TPQVKGGALPPAKRAKKPEEESES------SEEGS 277
Query: 229 SREKNTNQGFSSANVSEEEERKLFSVPSQLRAFTVPSVELSSAKPSQTSHLPTSLAADRT 288
E+ G S + E+ ++ + + + P + A P + + + A +
Sbjct: 278 ESEEEAPAGTRSQVKASEKILQVRAASAPAKG--TPGKGATPAPPGKAGAVASQTKAGKP 335
Query: 289 LHSTRSRADYPQSHVSSDTASHTPSVSITGAFSNSVSLKMGHVKLVSSPGRSEAETVDEP 348
+ S S SSD+ TP+ S K V S+P + P
Sbjct: 336 EEDSES-----SSEESSDSEEETPAAK--ALLQAKASGKTSQVGAASAPAKESPRKGAAP 388
Query: 349 VSEG-ADDSLDEFRINILSLDGLAPAVSENSDLEQEEESAQRQKTAGKIFRAEASTGQDA 407
G ++ + + D + + SE SD E+E + + RA ++ +++
Sbjct: 389 APPGKTGPAVAKAQAGKREED--SQSSSEESDSEEEAPAQAKPSGKAPQVRAASAPAKES 446
Query: 408 PRQAQARSWASQGKAASA------EGDESEVSEHLSASSASAIQQDSTSSMQPPSEAPMV 461
PR+ A + + A+A + ++S S S S A+ + + ++P ++P V
Sbjct: 447 PRKGAAPAPPRKTGPAAAQVQVGKQEEDSRSSSEESDSDREALAAMNAAQVKPLGKSPQV 506
Query: 462 NTVSS 466
S+
Sbjct: 507 KPAST 511
>gi|207113160 Treacher Collins-Franceschetti syndrome 1 isoform d
[Homo sapiens]
Length = 1488
Score = 53.5 bits (127), Expect = 6e-07
Identities = 88/429 (20%), Positives = 160/429 (37%), Gaps = 59/429 (13%)
Query: 108 KLQRNLSDTESDSMTADAGLPKRADRILSGGALELASQNTDKTSQNQARELPVTENNAQN 167
K ++ + ++ES ++D+ + A ++ A+Q Q + P N +
Sbjct: 600 KAEKPMDNSESSEESSDSADSEEAPAAMT------AAQAKPALKIPQTKACPKKTNTTAS 653
Query: 168 AKVSRFLKKKQAPVENISPEAPAGKERTLQTPKQKEPARTFDSPDSDEEEMKVLLGSLMD 227
AKV+ QAP + + +PAG + Q+ + S +SD EE K L +
Sbjct: 654 AKVAPVRVGTQAPRKAGTATSPAGSSPAVAGGTQRPAEDSSSSEESDSEEEKTGLAVTVG 713
Query: 228 SSREKNTNQGFSSANVSEEEERKLFSVPSQLRAFTVPSVELSSAKPSQTSHLPTSLAADR 287
++ +A+V V L T P + P +T T + A++
Sbjct: 714 QAKSVGKGLQVKAASV---------PVKGSLGQGTAPVL------PGKTGPTVTQVKAEK 758
Query: 288 TLHSTRSRADYPQSHVSSDTASHTPSVSITGAFSNSVSLKMGHVK-LVSSPGR---SEAE 343
S S + ++ A SV T A +N + + K +S+PG+ + A+
Sbjct: 759 QEDSESSEEESDSEEAAASPAQVKTSVKKTQAKANPAAARAPSAKGTISAPGKVVTAAAQ 818
Query: 344 TVDEPVSEGADDSLDEFRINIL-----SLDGLAPAVS-----------------ENSDLE 381
S+ + +L S+ + AV+ E SD E
Sbjct: 819 AKQRSPSKVKPPVRNPQNSTVLARGPASVPSVGKAVATAAQAQTGPEEDSGSSEEESDSE 878
Query: 382 QEEESAQRQKTAGKI--FRAEASTGQDAPRQAQARSWASQ-GKAASAEG---DESEVSEH 435
+E E+ + K +GK RA + +++PR+ A + + G +A+ G D SE
Sbjct: 879 EEAETLAQVKPSGKTHQIRAALAPAKESPRKGAAPTPPGKTGPSAAQAGKQDDSGSSSEE 938
Query: 436 LSASSASAIQQDSTSSMQP------PSEAPMVNTVSSAYSEDFENSPSLTASEPTAHSKE 489
+ + S ++P P+ +P + A ++ ASE TA S
Sbjct: 939 SDSDGEAPAAVTSAQVIKPPLIFVDPNRSPAGPAATPAQAQAASTPRKARASESTARSSS 998
Query: 490 SLDRTLDAL 498
S D +
Sbjct: 999 SESEDEDVI 1007
Score = 39.7 bits (91), Expect = 0.009
Identities = 74/365 (20%), Positives = 141/365 (38%), Gaps = 34/365 (9%)
Query: 113 LSDTESDSMTADAGLPKRADRILSGGALELASQNTDKTSQNQARELPVTENNAQNAKVSR 172
+S+TE + G + + S G + +S++T +S E + AQ S
Sbjct: 170 VSETEEEGSVPAFGAAAKPGMV-SAGQADSSSEDTSSSSDETDVEGKPSVKPAQVKASS- 227
Query: 173 FLKKKQAPVENISPEAPAGKERTLQTPKQK----EPARTFDSPDSDEEEMKVLLGSLMDS 228
+ K++P +P AP GK + TP+ K PA+ P+ + E S S
Sbjct: 228 -VSTKESPARKAAP-AP-GKVGDV-TPQVKGGALPPAKRAKKPEEESES------SEEGS 277
Query: 229 SREKNTNQGFSSANVSEEEERKLFSVPSQLRAFTVPSVELSSAKPSQTSHLPTSLAADRT 288
E+ G S + E+ ++ + + + P + A P + + + A +
Sbjct: 278 ESEEEAPAGTRSQVKASEKILQVRAASAPAKG--TPGKGATPAPPGKAGAVASQTKAGKP 335
Query: 289 LHSTRSRADYPQSHVSSDTASHTPSVSITGAFSNSVSLKMGHVKLVSSPGRSEAETVDEP 348
+ S S SSD+ TP+ S K V S+P + P
Sbjct: 336 EEDSES-----SSEESSDSEEETPAAK--ALLQAKASGKTSQVGAASAPAKESPRKGAAP 388
Query: 349 VSEG-ADDSLDEFRINILSLDGLAPAVSENSDLEQEEESAQRQKTAGKIFRAEASTGQDA 407
G ++ + + D + + SE SD E+E + + RA ++ +++
Sbjct: 389 APPGKTGPAVAKAQAGKREED--SQSSSEESDSEEEAPAQAKPSGKAPQVRAASAPAKES 446
Query: 408 PRQAQARSWASQGKAASA------EGDESEVSEHLSASSASAIQQDSTSSMQPPSEAPMV 461
PR+ A + + A+A + ++S S S S A+ + + ++P ++P V
Sbjct: 447 PRKGAAPAPPRKTGPAAAQVQVGKQEEDSRSSSEESDSDREALAAMNAAQVKPLGKSPQV 506
Query: 462 NTVSS 466
S+
Sbjct: 507 KPAST 511
>gi|57164975 Treacher Collins-Franceschetti syndrome 1 isoform b
[Homo sapiens]
Length = 1411
Score = 53.5 bits (127), Expect = 6e-07
Identities = 88/429 (20%), Positives = 160/429 (37%), Gaps = 59/429 (13%)
Query: 108 KLQRNLSDTESDSMTADAGLPKRADRILSGGALELASQNTDKTSQNQARELPVTENNAQN 167
K ++ + ++ES ++D+ + A ++ A+Q Q + P N +
Sbjct: 523 KAEKPMDNSESSEESSDSADSEEAPAAMT------AAQAKPALKIPQTKACPKKTNTTAS 576
Query: 168 AKVSRFLKKKQAPVENISPEAPAGKERTLQTPKQKEPARTFDSPDSDEEEMKVLLGSLMD 227
AKV+ QAP + + +PAG + Q+ + S +SD EE K L +
Sbjct: 577 AKVAPVRVGTQAPRKAGTATSPAGSSPAVAGGTQRPAEDSSSSEESDSEEEKTGLAVTVG 636
Query: 228 SSREKNTNQGFSSANVSEEEERKLFSVPSQLRAFTVPSVELSSAKPSQTSHLPTSLAADR 287
++ +A+V V L T P + P +T T + A++
Sbjct: 637 QAKSVGKGLQVKAASV---------PVKGSLGQGTAPVL------PGKTGPTVTQVKAEK 681
Query: 288 TLHSTRSRADYPQSHVSSDTASHTPSVSITGAFSNSVSLKMGHVK-LVSSPGR---SEAE 343
S S + ++ A SV T A +N + + K +S+PG+ + A+
Sbjct: 682 QEDSESSEEESDSEEAAASPAQVKTSVKKTQAKANPAAARAPSAKGTISAPGKVVTAAAQ 741
Query: 344 TVDEPVSEGADDSLDEFRINIL-----SLDGLAPAVS-----------------ENSDLE 381
S+ + +L S+ + AV+ E SD E
Sbjct: 742 AKQRSPSKVKPPVRNPQNSTVLARGPASVPSVGKAVATAAQAQTGPEEDSGSSEEESDSE 801
Query: 382 QEEESAQRQKTAGKI--FRAEASTGQDAPRQAQARSWASQ-GKAASAEG---DESEVSEH 435
+E E+ + K +GK RA + +++PR+ A + + G +A+ G D SE
Sbjct: 802 EEAETLAQVKPSGKTHQIRAALAPAKESPRKGAAPTPPGKTGPSAAQAGKQDDSGSSSEE 861
Query: 436 LSASSASAIQQDSTSSMQP------PSEAPMVNTVSSAYSEDFENSPSLTASEPTAHSKE 489
+ + S ++P P+ +P + A ++ ASE TA S
Sbjct: 862 SDSDGEAPAAVTSAQVIKPPLIFVDPNRSPAGPAATPAQAQAASTPRKARASESTARSSS 921
Query: 490 SLDRTLDAL 498
S D +
Sbjct: 922 SESEDEDVI 930
Score = 41.2 bits (95), Expect = 0.003
Identities = 75/332 (22%), Positives = 126/332 (37%), Gaps = 41/332 (12%)
Query: 122 TADAGLPKRADRILSGGALELASQNTDKTSQNQARELPVTENNAQNAKVSRFLKKKQAPV 181
T++ G ++A+ + A + + TS++ E E A+ AK + L + V
Sbjct: 56 TSELGRKRKAEEDAALQAKKTRVSDPISTSESSEEE---EEAEAETAKATPRLASTNSSV 112
Query: 182 ENISPEAPAGKERTLQTPKQKEPARTFDSPDSDEEEMKVLLGSLMDSSREKNTNQGFSSA 241
+ ++ +T K + + P + + +L G S E + N +
Sbjct: 113 LGADLPSSMKEKAKAETEKAGKTGNSMPHPATGKTVANLLSGKSPRKSAEPSAN----TT 168
Query: 242 NVSEEEERKLFSVPSQLRAFTVPSVELSSAKPSQTSHLPTSLAADRTLHSTRSRADYPQS 301
VSE EE SVP+ A P + SA + +S TS ++D T ++ Q
Sbjct: 169 LVSETEEEG--SVPA-FGAAAKPG--MVSAGQADSSSEDTSSSSDETDVEVKASEKILQV 223
Query: 302 HVSSDTASHTPSVSITGAFSNSVSLKMGHVKLVSSPGRSEAETVDEPVSEGADDSLDEFR 361
+S A TP T A K G V + G+ E ++ E SE + DS +E
Sbjct: 224 RAASAPAKGTPGKGATPAPPG----KAGAVASQTKAGKPEEDS--ESSSEESSDSEEETP 277
Query: 362 INILSLD-----------------------GLAPAVSENSDLEQEEESAQRQKTAGKIFR 398
L G APA + + A +++ +
Sbjct: 278 AAKALLQAKASGKTSQVGAASAPAKESPRKGAAPAPPGKTGPAVAKAQAGKREEDSQSSS 337
Query: 399 AEASTGQDAPRQAQARSWASQGKAASAEGDES 430
E+ + ++AP QA+ A Q +AASA ES
Sbjct: 338 EESDSEEEAPAQAKPSGKAPQVRAASAPAKES 369
Score = 37.7 bits (86), Expect = 0.034
Identities = 71/371 (19%), Positives = 138/371 (37%), Gaps = 32/371 (8%)
Query: 124 DAGLPKRADRILSGGALELASQNTDKTSQNQARELP---VTENNAQNAKVSRFLKKK-QA 179
DA L + R+ + +S+ ++ A+ P T ++ A + +K+K +A
Sbjct: 68 DAALQAKKTRVSDPISTSESSEEEEEAEAETAKATPRLASTNSSVLGADLPSSMKEKAKA 127
Query: 180 PVE------NISPEAPAGKE----RTLQTP-KQKEPARTFDSPDSDEEEMKV------LL 222
E N P GK + ++P K EP+ EEE V
Sbjct: 128 ETEKAGKTGNSMPHPATGKTVANLLSGKSPRKSAEPSANTTLVSETEEEGSVPAFGAAAK 187
Query: 223 GSLMDSSREKNTNQGFSSANVSEEEERKLFSVPSQLRAFTVPSVELSSAKPSQTSHLPTS 282
++ + + ++++ SS++ + E K Q+RA + P+ +
Sbjct: 188 PGMVSAGQADSSSEDTSSSSDETDVEVKASEKILQVRAASAPAKGTPGKGATPAPPGKAG 247
Query: 283 LAADRTLHSTRSRADYPQSHVSSDTASHTPSVSITGAFSNSVSLKMGHVKLVSSPGRSEA 342
A +T S SSD+ TP+ S K V S+P +
Sbjct: 248 AVASQTKAGKPEEDSESSSEESSDSEEETPAAK--ALLQAKASGKTSQVGAASAPAKESP 305
Query: 343 ETVDEPVSEG-ADDSLDEFRINILSLDGLAPAVSENSDLEQEEESAQRQKTAGKIFRAEA 401
P G ++ + + D + + SE SD E+E + + RA +
Sbjct: 306 RKGAAPAPPGKTGPAVAKAQAGKREED--SQSSSEESDSEEEAPAQAKPSGKAPQVRAAS 363
Query: 402 STGQDAPRQAQARSWASQGKAASA------EGDESEVSEHLSASSASAIQQDSTSSMQPP 455
+ +++PR+ A + + A+A + ++S S S S A+ + + ++P
Sbjct: 364 APAKESPRKGAAPAPPRKTGPAAAQVQVGKQEEDSRSSSEESDSDREALAAMNAAQVKPL 423
Query: 456 SEAPMVNTVSS 466
++P V S+
Sbjct: 424 GKSPQVKPAST 434
>gi|57164977 Treacher Collins-Franceschetti syndrome 1 isoform a [Homo
sapiens]
Length = 1450
Score = 53.5 bits (127), Expect = 6e-07
Identities = 88/429 (20%), Positives = 160/429 (37%), Gaps = 59/429 (13%)
Query: 108 KLQRNLSDTESDSMTADAGLPKRADRILSGGALELASQNTDKTSQNQARELPVTENNAQN 167
K ++ + ++ES ++D+ + A ++ A+Q Q + P N +
Sbjct: 600 KAEKPMDNSESSEESSDSADSEEAPAAMT------AAQAKPALKIPQTKACPKKTNTTAS 653
Query: 168 AKVSRFLKKKQAPVENISPEAPAGKERTLQTPKQKEPARTFDSPDSDEEEMKVLLGSLMD 227
AKV+ QAP + + +PAG + Q+ + S +SD EE K L +
Sbjct: 654 AKVAPVRVGTQAPRKAGTATSPAGSSPAVAGGTQRPAEDSSSSEESDSEEEKTGLAVTVG 713
Query: 228 SSREKNTNQGFSSANVSEEEERKLFSVPSQLRAFTVPSVELSSAKPSQTSHLPTSLAADR 287
++ +A+V V L T P + P +T T + A++
Sbjct: 714 QAKSVGKGLQVKAASV---------PVKGSLGQGTAPVL------PGKTGPTVTQVKAEK 758
Query: 288 TLHSTRSRADYPQSHVSSDTASHTPSVSITGAFSNSVSLKMGHVK-LVSSPGR---SEAE 343
S S + ++ A SV T A +N + + K +S+PG+ + A+
Sbjct: 759 QEDSESSEEESDSEEAAASPAQVKTSVKKTQAKANPAAARAPSAKGTISAPGKVVTAAAQ 818
Query: 344 TVDEPVSEGADDSLDEFRINIL-----SLDGLAPAVS-----------------ENSDLE 381
S+ + +L S+ + AV+ E SD E
Sbjct: 819 AKQRSPSKVKPPVRNPQNSTVLARGPASVPSVGKAVATAAQAQTGPEEDSGSSEEESDSE 878
Query: 382 QEEESAQRQKTAGKI--FRAEASTGQDAPRQAQARSWASQ-GKAASAEG---DESEVSEH 435
+E E+ + K +GK RA + +++PR+ A + + G +A+ G D SE
Sbjct: 879 EEAETLAQVKPSGKTHQIRAALAPAKESPRKGAAPTPPGKTGPSAAQAGKQDDSGSSSEE 938
Query: 436 LSASSASAIQQDSTSSMQP------PSEAPMVNTVSSAYSEDFENSPSLTASEPTAHSKE 489
+ + S ++P P+ +P + A ++ ASE TA S
Sbjct: 939 SDSDGEAPAAVTSAQVIKPPLIFVDPNRSPAGPAATPAQAQAASTPRKARASESTARSSS 998
Query: 490 SLDRTLDAL 498
S D +
Sbjct: 999 SESEDEDVI 1007
Score = 39.7 bits (91), Expect = 0.009
Identities = 74/365 (20%), Positives = 141/365 (38%), Gaps = 34/365 (9%)
Query: 113 LSDTESDSMTADAGLPKRADRILSGGALELASQNTDKTSQNQARELPVTENNAQNAKVSR 172
+S+TE + G + + S G + +S++T +S E + AQ S
Sbjct: 170 VSETEEEGSVPAFGAAAKPGMV-SAGQADSSSEDTSSSSDETDVEGKPSVKPAQVKASS- 227
Query: 173 FLKKKQAPVENISPEAPAGKERTLQTPKQK----EPARTFDSPDSDEEEMKVLLGSLMDS 228
+ K++P +P AP GK + TP+ K PA+ P+ + E S S
Sbjct: 228 -VSTKESPARKAAP-AP-GKVGDV-TPQVKGGALPPAKRAKKPEEESES------SEEGS 277
Query: 229 SREKNTNQGFSSANVSEEEERKLFSVPSQLRAFTVPSVELSSAKPSQTSHLPTSLAADRT 288
E+ G S + E+ ++ + + + P + A P + + + A +
Sbjct: 278 ESEEEAPAGTRSQVKASEKILQVRAASAPAKG--TPGKGATPAPPGKAGAVASQTKAGKP 335
Query: 289 LHSTRSRADYPQSHVSSDTASHTPSVSITGAFSNSVSLKMGHVKLVSSPGRSEAETVDEP 348
+ S S SSD+ TP+ S K V S+P + P
Sbjct: 336 EEDSES-----SSEESSDSEEETPAAK--ALLQAKASGKTSQVGAASAPAKESPRKGAAP 388
Query: 349 VSEG-ADDSLDEFRINILSLDGLAPAVSENSDLEQEEESAQRQKTAGKIFRAEASTGQDA 407
G ++ + + D + + SE SD E+E + + RA ++ +++
Sbjct: 389 APPGKTGPAVAKAQAGKREED--SQSSSEESDSEEEAPAQAKPSGKAPQVRAASAPAKES 446
Query: 408 PRQAQARSWASQGKAASA------EGDESEVSEHLSASSASAIQQDSTSSMQPPSEAPMV 461
PR+ A + + A+A + ++S S S S A+ + + ++P ++P V
Sbjct: 447 PRKGAAPAPPRKTGPAAAQVQVGKQEEDSRSSSEESDSDREALAAMNAAQVKPLGKSPQV 506
Query: 462 NTVSS 466
S+
Sbjct: 507 KPAST 511
>gi|55741473 HECT, C2 and WW domain containing E3 ubiquitin protein
ligase 2 [Homo sapiens]
Length = 1572
Score = 50.4 bits (119), Expect = 5e-06
Identities = 93/435 (21%), Positives = 153/435 (35%), Gaps = 53/435 (12%)
Query: 80 RPPTTASRIRANAALMKLAQ---LETRIMNRKLQRNLSDTESDSMTADAGLPKRADRILS 136
RP T R+ A KL +TR+ N L + SD E D G P +
Sbjct: 430 RPGTATCSERSMGASPKLRSSFPTDTRL-NAMLHID-SDEEDHEFQQDLGYPSSLEE--E 485
Query: 137 GGALELA----SQNTDKTSQNQARELPVTENNAQNAKVSRFLKKKQAPVENISPEAPAGK 192
GG + + + + TSQ + + PV A + + F K + E PAG
Sbjct: 486 GGLIMFSRASRADDGSLTSQTKLEDNPVENEEASTHEAASFEDKPENLPELAESSLPAG- 544
Query: 193 ERTLQTPKQKEPARTFDSPDSDEEEMKVLLGSLMDSSREKNTNQGFSSAN------VSEE 246
P +E + S ++ L GS + G S A+ VSE
Sbjct: 545 ------PAPEEGEGGPEPQPSADQGSAELCGSQEVDQPTSGADTGTSDASGGSRRAVSET 598
Query: 247 EERKLFSVPSQLRAFTVPSVELSSAKPSQTSHLPTSLAADRTLHSTRSRADYPQSHVSSD 306
E S PSQ+ + T PS + S+ S P +D + S +
Sbjct: 599 ESLDQGSEPSQVSSETEPSDPARTESVSEASTRP------------EGESDLECADSSCN 646
Query: 307 TASHTPSVSITGAFSNSVSLKMGHVKLVSSPGRSEAETVDEPVSEGADDSLDEFRINILS 366
+ T S+ S+ S + SS + EP S G + E S
Sbjct: 647 ESVTTQLSSVDTRCSSLESARFPETPAFSSQEEEDGACAAEPTSSGPAEGSQESVCTAGS 706
Query: 367 LDGLAPAVSENSDLEQEEESAQRQKTAGKIFRAE-----ASTGQDAPRQAQARSWASQGK 421
L + E+ E + Q+ G++++ A+ ++P Q + + +QG
Sbjct: 707 LPVVQVPSGEDEGPGAESATVPDQEELGEVWQRRGSLEGAAAAAESPPQEEGSAGEAQGT 766
Query: 422 AASAEGDE------SEVSEHLSASSASAIQQDSTSSMQ-----PPSEAPMVNTVSSAYSE 470
A E S+ + H S +++QD + + PP+ +++ +
Sbjct: 767 CEGATAQEEGATGGSQANGHQPLRSLPSVRQDVSRYQRVDEALPPNWEARIDSHGRIFYV 826
Query: 471 DFENSPSLTASEPTA 485
D N + T PTA
Sbjct: 827 DHVNR-TTTWQRPTA 840
>gi|167736355 mucin 4 isoform a [Homo sapiens]
Length = 5284
Score = 49.7 bits (117), Expect = 9e-06
Identities = 75/317 (23%), Positives = 126/317 (39%), Gaps = 31/317 (9%)
Query: 237 GFSSANVSEEEERKLFSVPSQL--RAFTVPSVELSSAKPSQTSHLPTSLAADRTLHSTRS 294
G SSA+ + + V S +A +P SSA T+ LP + D + ST
Sbjct: 1781 GLSSASTDDTTRLPVTDVSSASTGQAIPLPVTSPSSASTGDTTPLPVT---DASSASTGD 1837
Query: 295 RADYPQSHVSSDTASHTPSVSITGAFSNSVSLKMGH---VKLVSSPGRSEAETVDEPVSE 351
P + SS ++ HT S+ +T A S S GH + + + S +T PV++
Sbjct: 1838 TTSLPVTIPSSASSGHTTSLPVTDASSVST----GHATSLLVTDASSVSTGDTTPLPVTD 1893
Query: 352 GADDSL-DEFRINILSLDGLAPAVSENSDLEQEEESAQRQKTAGKIFR-AEASTGQDAPR 409
S D +++ ++ + + + ++ T + + AS+G P
Sbjct: 1894 TNSASTGDTTPLHVTDASSVSTGHATSLPVTSLSSASTGDTTPLPVTSPSSASSGHTTPL 1953
Query: 410 QAQARSWASQGKAASAE-GDESEVS------------EHLSASSASAIQQDSTSSMQPPS 456
S G A S D S VS +S A+ + TSS+
Sbjct: 1954 PVTDASSVPTGHATSLPVTDASSVSTGHATPLPVTDASSVSTGHATPLPVTDTSSVSTGQ 2013
Query: 457 EAPM-VNTVSSAYSEDFENSPSLTASEPTAHSKESLDRTLDALSESSSSVKTDLPQTAES 515
P+ V ++SSA + D +P +A + + + +LS S+ T LP T+ S
Sbjct: 2014 ATPLPVTSLSSASTGD--TTPLPVTDTSSASTGQDTPLPVTSLSSVSTGDTTPLPVTSPS 2071
Query: 516 RKKSGRHVTRVLVKDTA 532
+G H T +LV D +
Sbjct: 2072 SASTG-HATPLLVTDAS 2087
Score = 48.1 bits (113), Expect = 3e-05
Identities = 68/286 (23%), Positives = 111/286 (38%), Gaps = 16/286 (5%)
Query: 260 AFTVPSVELSSAKPSQTSHLPTSLAADRTLHSTRSRADYPQSHVSSDTASHTPSVSITGA 319
A ++P + SS T+ LP + D + ST P + SS + HT + +T A
Sbjct: 1102 ATSLPVTDTSSVSTGHTTPLPVT---DTSSASTGHATSLPVTDTSSVSTGHTTPLHVTDA 1158
Query: 320 FSNSVSLKMGHVKLVSSPGRSEAETVDEPVSEGADDSLDEFRINILSLDGLAPAVSENSD 379
S S + + + S S +T PV+ + S +L D + + +
Sbjct: 1159 SSASTG-QATPLPVTSLSSVSTGDTTPLPVTSPSSASTGH-ATPLLVTDTSSASTGHATP 1216
Query: 380 LEQEEESAQRQKTAGKI---FRAEASTGQDAPRQAQARSWASQGKAASAEGDESEVSEHL 436
L + S+ A + + ASTG P S AS G+A S + + +
Sbjct: 1217 LPVTDASSVSTDHATSLPVTIPSAASTGHTTPLPVTDTSSASTGQATSLLVTD---TSSV 1273
Query: 437 SASSASAIQQDSTSSMQPPSEAPMVNTVSSAYSEDFENSPSLTASEPTAHSKESLDRTLD 496
S + + STSS P+ T S+ S +P S +A + +++ +
Sbjct: 1274 STGDTTPLPVTSTSSASTGHVTPLHVTSPSSASTG-HATPLPVTSLSSASTGDTMPLPVT 1332
Query: 497 ALSESSSSVKTDLPQTAESRKKSGR----HVTRVLVKDTAVQTPDP 538
+ S +S+ T LP T S +G HVT T TP P
Sbjct: 1333 SPSSASTGDTTPLPVTDASSVSTGHTTPLHVTDASSASTGQATPLP 1378
Score = 42.7 bits (99), Expect = 0.001
Identities = 63/276 (22%), Positives = 108/276 (39%), Gaps = 26/276 (9%)
Query: 263 VPSVELSSAKPSQTSHLPTSLAADRTLHSTRSRADYPQSHVSSDTASHTPSVSITGAFS- 321
+P SSA T+ LP + D + S P + SS + HT + +T S
Sbjct: 1569 LPVTSPSSASTGHTTPLPVT---DTSSASKGDTTPLPVTSPSSASTGHTTPLPVTDTSSA 1625
Query: 322 -----------NSVSLKMGHVKLVSSPGRSEAETVD-EPVSEGADDSLDEFRINILSLDG 369
N+ SL GH + S A T P+ + S L + G
Sbjct: 1626 STGDTTPLPVTNASSLSTGHATPLHVTSPSSASTGHATPLPVTSTSSASTGHATPLPVTG 1685
Query: 370 LAPAVSENS---DLEQEEESAQRQKTAGKIFR-AEASTGQDAPRQAQARSWASQGKAASA 425
L+ A ++++ + ++ Q T + + STG P + S AS G A+
Sbjct: 1686 LSSATTDDTTRLPVTDVSSASTGQATPLPVTSLSSVSTGDTTPLPVTSPSSASTGHASPL 1745
Query: 426 EGDESEVSEHLSASSASAIQQDSTSSMQPPSEAPM-VNTVSSAYSEDFENSPSLTASEPT 484
++ + S A+ + TSS+ P+ V +SSA ++D P S +
Sbjct: 1746 LVTDASSA---STGQATPLPVTDTSSVSTAHATPLPVTGLSSASTDDTTRLPVTDVS--S 1800
Query: 485 AHSKESLDRTLDALSESSSSVKTDLPQTAESRKKSG 520
A + +++ + + S +S+ T LP T S +G
Sbjct: 1801 ASTGQAIPLPVTSPSSASTGDTTPLPVTDASSASTG 1836
Score = 42.4 bits (98), Expect = 0.001
Identities = 93/442 (21%), Positives = 169/442 (38%), Gaps = 42/442 (9%)
Query: 131 ADRILSGGALELASQNTDKTSQNQARELPVTENNAQNAKVSRFLKKKQAPVENISPEAPA 190
A + +G A L +T S LPVT+ ++ + + L PV ++S +
Sbjct: 3462 ASSVSTGHATPLPVTDTSSASTGDTTRLPVTDTSSASTGQATPL-----PVTSLSSVSTG 3516
Query: 191 GKERTLQTPKQK-EPARTFDSPDSDEEEMKVLLGSLMDSSREKNTNQGFSSANVSEEEER 249
L T P +D S D++R T+ SSA+ +
Sbjct: 3517 DTTPLLVTDASSVSTGHATPLPVTDTSS-----ASTGDTTRLPVTDT--SSASTGQATPL 3569
Query: 250 KLFSVPSQLRAFTVPSVELSSAKPSQTSHLPTSLAADRTLHSTRSRADYPQSHVSSDTAS 309
+ ++PS + + ++S T H+ + ST P + SS +
Sbjct: 3570 PV-TIPSSSSSGHTTPLPVTSTSSVSTGHVTPLHVTSPSSASTGHVTPLPVTSTSSASTG 3628
Query: 310 HTPSVSITGAFSNSVSLKMGH---VKLVSSPGRSEAETVDEPVSEGADDSLDEFR-INIL 365
H + +T A S S GH + + + S +T PV++ + S + + +
Sbjct: 3629 HATPLLVTDASSVST----GHATPLPVTDASSASTGDTTPLPVTDTSSASTGQATPLPVT 3684
Query: 366 SLDGLAPAVSENSDLEQEEESAQRQKTAGKI-FRAEASTGQDAPRQAQARSWASQGKA-- 422
SL ++ + + ++ T + + STG P + S AS G A
Sbjct: 3685 SLSSVSTGDTTPLPVTDASSASTGHATPLPVTIPSSVSTGDTMPLPVTSPSSASTGHATP 3744
Query: 423 -------ASAEGDES--EVSEHLSASSASA----IQQDSTSSMQPPSEAPMVNTVSSAYS 469
+++ GD + V++ SAS+ A + S++S + P V VSSA +
Sbjct: 3745 LPVTGLSSASTGDTTPLPVTDTSSASTRHATPLPVTDTSSASTDDTTRLP-VTDVSSAST 3803
Query: 470 EDFENSPSLTASEPTAHSKESLDRTLDALSESSSSVKTDLPQTAESRKKSGRHVTRVLVK 529
+P S +A + ++ + S S+ T LP T+ S +G H T + V
Sbjct: 3804 G--HATPLPVTSTSSASTGDTTPLPVTDTSSVSTGHATSLPVTSRSSASTG-HATPLPVT 3860
Query: 530 DTAVQTPDPAFTYEWTKVASMA 551
DT+ + A T +S++
Sbjct: 3861 DTSSVSTGHATPLPVTSTSSVS 3882
Score = 41.6 bits (96), Expect = 0.002
Identities = 87/411 (21%), Positives = 144/411 (35%), Gaps = 43/411 (10%)
Query: 147 TDKTSQNQARELPVTENNAQNAKVSRFLKKKQAPVENISPEAPAGKERTLQTPKQKEPAR 206
T + SQ P+T+ S F +P E + +AP T P
Sbjct: 645 TTQESQTTRSVSPMTDTKTVTTPGSSFTASGHSPSEIVPQDAPTISAATTFAPAPTGDGH 704
Query: 207 TFDSPDSDEEEMKVLLGSLMDSSREKNTNQGFSSANVSEEEERKLFSVPSQLRAFTVPSV 266
T +P + +L + + G S S + L S + P
Sbjct: 705 TTQAPTT----------ALQAAPSSHDATLG-PSGGTSLSKTGALTLANSVVSTPGGPEG 753
Query: 267 ELSSAKPSQTSHLPTSLA----ADRTLHSTRSRADYPQSHVSSDTASHTPSVSITGAFSN 322
+ +SA S + ++ A+ T S +++ P S S T++ T + S +GA
Sbjct: 754 QWTSASASTSPDTAAAMTHTHQAESTEASGQTQTSEPASSGSRTTSAGTATPSSSGASGT 813
Query: 323 SVSLKMGHVKLVSSPGRSEAETVDEPVSEGADDSLDEFRINILSLDGLAPAVSENSDLEQ 382
+ S G +S+ G ET + D + +LS A+ ++ +
Sbjct: 814 TPSGSEG----ISTSG----ETTRFSSNPSRDSHTTQSTTELLSASASHGAIPVSTGMAS 865
Query: 383 EEESAQRQKTAGKIFRAEASTGQDAPRQAQARSWASQGKAASAEGDESEVSEHLSASSAS 442
T + A TGQ +P A + + A+ + S S + +
Sbjct: 866 SIVPGTFHPTLSEASTAGRPTGQSSPTSPSASPQETAAISRMAQTQRTRTSRG-SDTISL 924
Query: 443 AIQQDSTSSMQPPSEAPMVNT-VSSAYSEDFENSPS-------------LTASEPTAHSK 488
A Q T S PP+ + +T ++S +E SPS T T S
Sbjct: 925 ASQATDTFSTVPPTPPSITSTGLTSPQTETHTLSPSGSGKTFTTALISNATPLPVTYASS 984
Query: 489 ESLDRTLDALSESSSSVK----TDLPQTAESRKKSGRHVTRVLVKDTAVQT 535
S T +SSV T LP T+ S +G H T + V DT+ ++
Sbjct: 985 ASTGHTTPLHVTDASSVSTGHATPLPVTSPSSVSTG-HTTPLPVTDTSSES 1034
Score = 40.8 bits (94), Expect = 0.004
Identities = 69/291 (23%), Positives = 114/291 (39%), Gaps = 27/291 (9%)
Query: 260 AFTVPSVELSSAKPSQTSHLPTSLAADRTLHSTRSRADYPQSHVSSDTASHTPSVSITGA 319
A VP SSA T+ LP + D + ST P + SS + HT + +T
Sbjct: 3310 ATPVPVTSTSSASTGHTTPLPVT---DTSSASTGDTTPLPVTSPSSASTGHTTPLHVTIP 3366
Query: 320 FSNSVSLKMGHVKLVSSPGRSEAET---VDEPVSEGADDSLDEFR-INILSLDGLAPAVS 375
S S G + G S A T PV++ + S + + SL ++ +
Sbjct: 3367 SSAST----GDTSTLPVTGASSASTGHATPLPVTDTSSVSTGHATPLPVTSLSSVSTGDT 3422
Query: 376 ENSDLEQEEESAQRQKTAGKIFR-AEASTGQDAPRQAQARSWASQGKA---------ASA 425
+ ++ Q T + + STG P S S G A +++
Sbjct: 3423 TPLPVTDASSASTGQATPLPVTSLSSVSTGDTTPLLVTDASSVSTGHATPLPVTDTSSAS 3482
Query: 426 EGDESE--VSEHLSASS--ASAIQQDSTSSMQPPSEAPMVNTVSSAYSEDFENSPSLTAS 481
GD + V++ SAS+ A+ + S SS+ P++ T +S+ S +P
Sbjct: 3483 TGDTTRLPVTDTSSASTGQATPLPVTSLSSVSTGDTTPLLVTDASSVSTG-HATPLPVTD 3541
Query: 482 EPTAHSKESLDRTLDALSESSSSVKTDLPQTAESRKKSGRHVTRVLVKDTA 532
+A + ++ + S +S+ T LP T S SG H T + V T+
Sbjct: 3542 TSSASTGDTTRLPVTDTSSASTGQATPLPVTIPSSSSSG-HTTPLPVTSTS 3591
Score = 39.3 bits (90), Expect = 0.012
Identities = 76/334 (22%), Positives = 122/334 (36%), Gaps = 33/334 (9%)
Query: 255 PSQLRAFTVPSVELSSAKPSQTSHLPTSLAADRTLHSTRSRADYPQSHVSSDTASHTPSV 314
PS V + ++S + T H L D + ST P + SS + T +
Sbjct: 3606 PSSASTGHVTPLPVTSTSSASTGHATPLLVTDASSVSTGHATPLPVTDASSASTGDTTPL 3665
Query: 315 SITGAFSNSVSLKMGHVKLVSSPGRSEAETVDEPVSEGADDSLDEFRINILSLDGLAPAV 374
+T S S + + + S S +T PV++ + S + L P+
Sbjct: 3666 PVTDTSSASTG-QATPLPVTSLSSVSTGDTTPLPVTDASSASTG----HATPLPVTIPSS 3720
Query: 375 SENSDLEQEEESAQRQKTAGKIF------RAEASTGQDAPRQAQARSWASQGKA------ 422
D ++ + G + ASTG P S AS A
Sbjct: 3721 VSTGDTMPLPVTSPSSASTGHATPLPVTGLSSASTGDTTPLPVTDTSSASTRHATPLPVT 3780
Query: 423 --ASAEGDES---EVSEHLSASS--ASAIQQDSTSSMQPPSEAPMVNTVSSAYSEDFENS 475
+SA D++ V++ SAS+ A+ + STSS P+ T +S+ S S
Sbjct: 3781 DTSSASTDDTTRLPVTDVSSASTGHATPLPVTSTSSASTGDTTPLPVTDTSSVSTGHATS 3840
Query: 476 PSLTASEPTAHSKESLDRTLDALSESSSSVKTDLPQTAESRKKSGRHVTRVLVKDTAVQT 535
+T S +A + + + S S+ T LP T+ S +G H T + V +
Sbjct: 3841 LPVT-SRSSASTGHATPLPVTDTSSVSTGHATPLPVTSTSSVSTG-HATPL-----PVTS 3893
Query: 536 PDPAFTYEWTKVASMAAMGPALGGAYVDPTPIAN 569
P A T T V + + G P P+ N
Sbjct: 3894 PSSASTGHATPVPVTSTSSASTGD--TTPLPVTN 3925
Score = 38.5 bits (88), Expect = 0.020
Identities = 89/405 (21%), Positives = 146/405 (36%), Gaps = 46/405 (11%)
Query: 134 ILSGGALELASQNTDKTSQNQARELPVTENNAQNAKVSRFLKKKQAPVENISPEAPAGKE 193
+ +G A L +T S A LPVT+ ++ + + L PV + S A G+
Sbjct: 2153 VSTGHATSLPVTDTSSASTGHATSLPVTDTSSASTGHATPL-----PVTDTS-SASTGQA 2206
Query: 194 RTLQTPKQKEPARTFDSPDSDEEEMKVLLGSLMDSSREKNTNQGFSSANVSEEEERKLFS 253
L T S S + +L+ SSA+ + + S
Sbjct: 2207 TPLPV--------TSPSSASTGHAIPLLVTDT-------------SSASTGQATPLPVTS 2245
Query: 254 VPSQLRAFTVPSVELSSAKPSQTSHLPTSLAADRTLHSTRSRADYPQSHVSSDTASHTPS 313
+ S T P + ++ A T H + + ST P + SS + H
Sbjct: 2246 LSSASTGDTTP-LPVTDASSVSTGHATSLPVTSLSSVSTGDTTPLPVTSPSSASTGHATP 2304
Query: 314 VSITGAFSNSVSLKMGH---VKLVSSPGRSEAETVDEPVSEGADDSLDEFR-INILSLDG 369
+ +T A S S GH + + S S +T PV+ + S +++
Sbjct: 2305 LHVTDASSAST----GHATPLPVTSLSSASTGDTTPLPVTSPSSASTGHATPLHVTDASS 2360
Query: 370 LAPAVSENSDLEQEEESAQRQKTAGKIFRA-EASTGQDAPRQAQARSWASQGKAA--SAE 426
++ + + ++ T + A ASTG P S AS G A
Sbjct: 2361 VSTGDTTPLPVTSSSSASSGHTTPLPVTDASSASTGDTTPLPVTDTSSASTGHATHLPVT 2420
Query: 427 GDESEVSEHLSASSASAIQQDSTSSMQPPSEAPMVNTVSSAYSEDFENSPSLTASEPTAH 486
G S + + + + ST P P+ +T S++ + + T+S T H
Sbjct: 2421 GLSSASTGDTTRLPVTNVSSASTGHATP---LPVTSTSSASTGDTTPLPGTDTSSVSTGH 2477
Query: 487 SKESLDRTLDALSESSSSVKTDLPQTAESRKKSGRHVTRVLVKDT 531
+ L DA S S+ T LP T+ S +G H T + V DT
Sbjct: 2478 TTPLL--VTDASSVSTGDT-TRLPVTSPSSASTG-HTTPLPVTDT 2518
Score = 38.5 bits (88), Expect = 0.020
Identities = 70/296 (23%), Positives = 110/296 (37%), Gaps = 37/296 (12%)
Query: 263 VPSVELSSAKPSQTSHLPTSLAADRTLHSTRSRADYPQSHVSSDTASHTPSVSITGAFSN 322
+P ++SSA Q + LP + + + ST P + SS + H + +T S
Sbjct: 3249 LPVTDISSASTGQATPLPVT---NTSSVSTGDTMPLPVTSPSSASTGHATPLPVTSTSSA 3305
Query: 323 SVSLKMGH---VKLVSSPGRSEAETVDEPVSEGADDSLDEFRINILSLDGLAPAVSENSD 379
S GH V + S+ S T PV++ + S + P S +S
Sbjct: 3306 ST----GHATPVPVTSTSSASTGHTTPLPVTDTSSASTGD--------TTPLPVTSPSS- 3352
Query: 380 LEQEEESAQRQKTAGKIFRAEASTGQDAPRQAQARSWASQGKAASAEGDESEVSEHLSAS 439
S + ASTG + S AS G A + + +S
Sbjct: 3353 -----ASTGHTTPLHVTIPSSASTGDTSTLPVTGASSASTGHATPLPVTD---TSSVSTG 3404
Query: 440 SASAIQQDSTSSMQPPSEAPMVNTVSSAYSEDFENSPSLTASEPTAHSKESLDRTLDALS 499
A+ + S SS+ P+ T +S+ S + T T+ S S T L
Sbjct: 3405 HATPLPVTSLSSVSTGDTTPLPVTDASSAS-----TGQATPLPVTSLSSVSTGDTTPLLV 3459
Query: 500 ESSSSVK----TDLPQTAESRKKSGRHVTRVLVKDTAVQTPDPAFTYEWTKVASMA 551
+SSV T LP T S +G TR+ V DT+ + A T ++S++
Sbjct: 3460 TDASSVSTGHATPLPVTDTSSASTG-DTTRLPVTDTSSASTGQATPLPVTSLSSVS 3514
Score = 38.1 bits (87), Expect = 0.026
Identities = 69/312 (22%), Positives = 114/312 (36%), Gaps = 25/312 (8%)
Query: 239 SSANVSEEEERKLFSVPSQLRAFTVPSVELSSAKPSQTSHLPTSLAADRTLHSTRSRADY 298
SSA+ + + S S T P + ++ A T H D + ST
Sbjct: 1319 SSASTGDTMPLPVTSPSSASTGDTTP-LPVTDASSVSTGHTTPLHVTDASSASTGQATPL 1377
Query: 299 PQSHVSSDTASHTPSVSITGAFSNSVSLKMGHVKLVSSPGRSEAET---VDEPVSEGADD 355
P + +SS + T + +T S S GH + S A T PV++ +
Sbjct: 1378 PVTSLSSVSTGDTTPLPVTSPSSAST----GHATPLLVTDTSSASTGHATPLPVTDASSV 1433
Query: 356 SLDEFRINILSLDGLAPAVSENSDLEQEEESAQRQKTAGKIF---RAEASTGQDAPRQAQ 412
S D +++ A + + L + S+ A + + STG P
Sbjct: 1434 STDHATSLPVTIPS-AASTGHTTPLPVTDTSSASTGQATSLLVTDTSSVSTGDTTPLPVT 1492
Query: 413 ARSWASQGKAA--SAEGDESEVSEHLSASSASAIQQDSTSSMQP-----PSEAPMVNT-- 463
+ S AS G S + H + +++ ST P PS A +T
Sbjct: 1493 STSSASTGHVTPLHVTSPSSASTGHATPLPVTSLSSASTGDTMPLPVTSPSSASTGDTTP 1552
Query: 464 --VSSAYSEDFENSPSLTASEP-TAHSKESLDRTLDALSESSSSVKTDLPQTAESRKKSG 520
V+ A S ++ L + P +A + + + S +S T LP T+ S +G
Sbjct: 1553 LPVTDASSVSTGHTTPLPVTSPSSASTGHTTPLPVTDTSSASKGDTTPLPVTSPSSASTG 1612
Query: 521 RHVTRVLVKDTA 532
H T + V DT+
Sbjct: 1613 -HTTPLPVTDTS 1623
Score = 35.8 bits (81), Expect = 0.13
Identities = 75/329 (22%), Positives = 115/329 (34%), Gaps = 39/329 (11%)
Query: 237 GFSSANVSEEEERKLFSVPSQL--RAFTVPSVELSSAKPSQTSHLPTS------------ 282
G SSA+ + + +V S A +P SSA T+ LP +
Sbjct: 2421 GLSSASTGDTTRLPVTNVSSASTGHATPLPVTSTSSASTGDTTPLPGTDTSSVSTGHTTP 2480
Query: 283 -LAADRTLHSTRSRADYPQSHVSSDTASHTPSVSITGA------------FSNSVSLKMG 329
L D + ST P + SS + HT + +T +N+ SL
Sbjct: 2481 LLVTDASSVSTGDTTRLPVTSPSSASTGHTTPLPVTDTPSASTGDTTPLPVTNASSLSTR 2540
Query: 330 H---VKLVSSPGRSEAETVDEPVSEGADDSLDEFR-INILSLDGLAPAVSENSDLEQEEE 385
H + + S S PV++ + S + + S + + +
Sbjct: 2541 HATSLHVTSPSSASTGHATSLPVTDTSAASTGHATPLPVTSTSSASTGDTTPLPVTDTYS 2600
Query: 386 SAQRQKTAGKIF-RAEASTGQDAPRQAQARSWASQGKAASAEGDESEVSEHLSASSASAI 444
++ Q T + + ASTG P S AS G A + +S A+ +
Sbjct: 2601 ASTGQATPLPVTDTSSASTGDTTPLPVTDTSSASTGHATPLPVTN---TSSVSTGHATPL 2657
Query: 445 QQDSTSSMQPPSEAPMVNTVSSAYSEDFENS-PSLTASEPTAHSKESLDRTLDALSESSS 503
S SS P+ T +S+ S S P AS SL T+ S +SS
Sbjct: 2658 HVTSPSSASTGHTTPLPVTDASSVSTGHATSLPVTDASSVFTGHATSLPVTIP--SSASS 2715
Query: 504 SVKTDLPQTAESRKKSGRHVTRVLVKDTA 532
T LP T S +G H T + V D +
Sbjct: 2716 GHTTPLPVTDASSVSTG-HATSLPVTDAS 2743
Score = 35.0 bits (79), Expect = 0.22
Identities = 100/444 (22%), Positives = 157/444 (35%), Gaps = 62/444 (13%)
Query: 113 LSDTESDSMTADAGLPKRADRILSGG-ALELASQNTDKTSQNQARELPVTENNAQNAKVS 171
++DT S S LP S G A L +T S A LPVT+ ++ + +
Sbjct: 2819 VTDTSSASTGHATSLPVTDTSSASTGHATPLPDTDTSSASTGHATLLPVTDTSSASIGHA 2878
Query: 172 RFLKKKQAPVENISPEAPAGKERTLQ--TPKQKEPARTFDSPDSDEEEMKVLLGSLMDSS 229
L PV + S G L +P P +D + + +
Sbjct: 2879 TSL-----PVTDTS-SISTGHATPLHVTSPSSASTGHATPLPVTDTSSASTGHANPLHVT 2932
Query: 230 REKNTNQGFSSANVSEEEERKLFSVPSQLRAFTVPSVELSSAKPSQTSHLP-TSLAADRT 288
+ + G ++ + S S A +P LSS T+ LP TS ++ T
Sbjct: 2933 SPSSASTGHATPLPVTDT-----SSASTGHATPLPVTSLSSVSTGDTTPLPVTSPSSAST 2987
Query: 289 LHSTRSRADYPQSHVSSDTASHTPSVSITGAFSNSVSLKMGHVKLVSSPGRSEAETVDEP 348
H+T P + SS + ++ +T S+ S +T P
Sbjct: 2988 GHTT----PLPVTDTSSASTGQATALPVT-----------------STSSASTGDTTPLP 3026
Query: 349 VSEGADDSLDEFR-INILSLDGLAPAVSENSDLEQEEESAQRQKTAGKIFRA-EASTGQD 406
V++ + S + + + SL ++ + + ++ T + A ASTGQ
Sbjct: 3027 VTDTSSASTGQATPLPVTSLSSVSTGDTTPLPVTSPSSASTGHATPLLVTDASSASTGQA 3086
Query: 407 APRQAQARSWASQGKAASAEGDESEVSEHLSASSASA----IQQDSTSSMQPPSEAPMVN 462
P + S S G V+ SAS+ A + S++S + P+ +
Sbjct: 3087 TPLPVTSLSSVSTGDTTPL-----PVTSPSSASTGHATSLPVTDTSSASTGDTTSLPVTD 3141
Query: 463 TVSSAYSEDFENSPSLTASEPTAHSKESLDRTLDALSESSSSVK----TDLPQTAESRKK 518
T SSAY+ D + P T S S T L +SSV T L T S
Sbjct: 3142 T-SSAYTGDTTSLP------VTDTSSSSTGDTTPLLVTETSSVSTGHATPLLVTDASSAS 3194
Query: 519 SGR----HVTRVLVKDTAVQTPDP 538
+G HVT T TP P
Sbjct: 3195 TGHATPLHVTSPSSASTGDTTPVP 3218
Score = 34.7 bits (78), Expect = 0.29
Identities = 56/283 (19%), Positives = 104/283 (36%), Gaps = 10/283 (3%)
Query: 253 SVPSQLRAFTVPSVELSSAKPSQTSHLPTSLAADRTLHSTRSRADYPQSHVSSDTASHTP 312
++PS ++ ++ A + T H D + ST P + +SS + T
Sbjct: 3364 TIPSSASTGDTSTLPVTGASSASTGHATPLPVTDTSSVSTGHATPLPVTSLSSVSTGDTT 3423
Query: 313 SVSITGAFSNSVSLKMGHVKLVSSPGRSEAETVDEPVSEGADDSLDEFRINILSLDGLAP 372
+ +T A S S + + + S S +T V++ + S + D +
Sbjct: 3424 PLPVTDASSASTG-QATPLPVTSLSSVSTGDTTPLLVTDASSVSTGH-ATPLPVTDTSSA 3481
Query: 373 AVSENSDLEQEEESAQRQKTAGKI---FRAEASTGQDAPRQAQARSWASQGKAASAEGDE 429
+ + + L + S+ A + + STG P S S G A +
Sbjct: 3482 STGDTTRLPVTDTSSASTGQATPLPVTSLSSVSTGDTTPLLVTDASSVSTGHATPLPVTD 3541
Query: 430 SEVSEHLSASSASAIQQDSTSSMQPPSEAPMVNTVSSAYSEDFENSPSLTASEPTAHSKE 489
+ + S + + TSS P+ T+ S+ S +P S + +
Sbjct: 3542 TSSA---STGDTTRLPVTDTSSASTGQATPLPVTIPSS-SSSGHTTPLPVTSTSSVSTGH 3597
Query: 490 SLDRTLDALSESSSSVKTDLPQTAESRKKSGRHVTRVLVKDTA 532
+ + S +S+ T LP T+ S +G H T +LV D +
Sbjct: 3598 VTPLHVTSPSSASTGHVTPLPVTSTSSASTG-HATPLLVTDAS 3639
Score = 34.7 bits (78), Expect = 0.29
Identities = 65/308 (21%), Positives = 104/308 (33%), Gaps = 33/308 (10%)
Query: 253 SVPSQLRAFTVPSVELSSAKPSQTSHLPTSLAADRTLHSTRSRADYPQSHVSSDTASHTP 312
++PS + + ++S + T H + ST P + SS + H
Sbjct: 3716 TIPSSVSTGDTMPLPVTSPSSASTGHATPLPVTGLSSASTGDTTPLPVTDTSSASTRHAT 3775
Query: 313 SVSITGAFSNSV------------SLKMGHVKLVSSPGRSEAETVD---------EPVSE 351
+ +T S S S GH + S A T D VS
Sbjct: 3776 PLPVTDTSSASTDDTTRLPVTDVSSASTGHATPLPVTSTSSASTGDTTPLPVTDTSSVST 3835
Query: 352 GADDSLDEFRINILSLDGLAP-AVSENSDLEQEEESAQRQKTAGKIFRAEASTGQDAPRQ 410
G SL + S P V++ S + + + + STG P
Sbjct: 3836 GHATSLPVTSRSSASTGHATPLPVTDTSSVSTGHATPLPVTSTSSV-----STGHATPLP 3890
Query: 411 AQARSWASQGKAASAEGDESEVSEHLSASSASAIQQDSTSSMQPPSEAPM-VNTVSSAYS 469
+ S AS G A + + S + + + SS+ P+ V + SSA
Sbjct: 3891 VTSPSSASTGHATPVPVTSTSSA---STGDTTPLPVTNASSLSTGHATPLHVTSPSSASR 3947
Query: 470 EDFENSPSLTASEPTAHSKESLDRTLDALSESSSSVKTDLPQTAESRKKSGRHVTRVLVK 529
D P AS +A + + L +LS S+ T LP T S +G+ +
Sbjct: 3948 GDTSTLPVTDAS--SASTGHATPLPLTSLSSVSTGDTTPLPVTDTSSASTGQATPLPVTS 4005
Query: 530 DTAVQTPD 537
++V T D
Sbjct: 4006 LSSVSTGD 4013
Score = 32.7 bits (73), Expect = 1.1
Identities = 68/284 (23%), Positives = 103/284 (36%), Gaps = 51/284 (17%)
Query: 263 VPSVELSSAKPSQTSHLPTSLAADRTLHSTRSRADYPQSHVSSDTASHTPSVSITGAFSN 322
+P + SS + LP + D + ST P + SS + H + +T S
Sbjct: 2145 LPVTDTSSVSTGHATSLPVT---DTSSASTGHATSLPVTDTSSASTGHATPLPVTDTSS- 2200
Query: 323 SVSLKMGHVKLVSSPGRSEAETVDEPVSEGADDSLDEFRINILSLDGLAPAVSENSDLEQ 382
+S G++ V P S + I +L D + + + + L
Sbjct: 2201 ------------ASTGQATPLPVTSPSSASTGHA-----IPLLVTDTSSASTGQATPLPV 2243
Query: 383 EEESAQRQKTAGKIFRAEASTGQDAPRQAQARSWASQGKAAS---------AEGDES--E 431
S+ ASTG P S S G A S + GD +
Sbjct: 2244 TSLSS-------------ASTGDTTPLPVTDASSVSTGHATSLPVTSLSSVSTGDTTPLP 2290
Query: 432 VSEHLSASS--ASAIQQDSTSSMQPPSEAPM-VNTVSSAYSEDFENSPSLTASEPTAHSK 488
V+ SAS+ A+ + SS P+ V ++SSA + D P + S +
Sbjct: 2291 VTSPSSASTGHATPLHVTDASSASTGHATPLPVTSLSSASTGDTTPLPVTSPSSASTGHA 2350
Query: 489 ESLDRTLDALSESSSSVKTDLPQTAESRKKSGRHVTRVLVKDTA 532
L T DA S S+ T LP T+ S SG H T + V D +
Sbjct: 2351 TPLHVT-DASSVSTGDT-TPLPVTSSSSASSG-HTTPLPVTDAS 2391
Score = 32.3 bits (72), Expect = 1.4
Identities = 82/410 (20%), Positives = 145/410 (35%), Gaps = 47/410 (11%)
Query: 136 SGGALELASQNTDKTSQNQARELPVTENNAQNAKVSRFLKKKQAPVENISPEAPAGKERT 195
+G A L +T S LPVT+ ++ + + L PV N S G
Sbjct: 2603 TGQATPLPVTDTSSASTGDTTPLPVTDTSSASTGHATPL-----PVTNTS-SVSTGHATP 2656
Query: 196 LQ--TPKQKEPARTFDSPDSDEEEMKVLLGSLMDSSREKNTNQGFSSANVSEEEERKLFS 253
L +P T P +D + + + + + G +++ +
Sbjct: 2657 LHVTSPSSASTGHTTPLPVTDASSVSTGHATSLPVTDASSVFTGHATSLP--------VT 2708
Query: 254 VPSQLRAFTVPSVELSSAKPSQTSHLPTSLAADRTLHSTRSRADYPQSHVSSDTASHTPS 313
+PS + + ++ A T H + D + ST P + SS + H
Sbjct: 2709 IPSSASSGHTTPLPVTDASSVSTGHATSLPVTDASSVSTGHATPLPVTDASSVSTGHATP 2768
Query: 314 VSITGAFSNSVSLKMGHVKLVSSPGRSEAETVDEPVSEGADDSLDEFR-INILSLDGLAP 372
+ +T S S +T PV++ + S + + + SL ++
Sbjct: 2769 LPLTSLSSVST-----------------GDTTPLPVTDTSSASTGQATPLPVTSLSSVST 2811
Query: 373 AVSENSDLEQEEESAQRQKTAGKIF-RAEASTGQDAPRQAQARSWASQGKAASAEGDESE 431
+ + ++ T+ + + ASTG P S AS G A ++
Sbjct: 2812 GDTTPLPVTDTSSASTGHATSLPVTDTSSASTGHATPLPDTDTSSASTGHATLLPVTDTS 2871
Query: 432 VSEHLSASSASAIQQDSTSSMQPPSEAPM-VNTVSSAYSEDFENSP-SLTASEPTAHSKE 489
+ S A+++ TSS+ P+ V + SSA + P + T+S T H+
Sbjct: 2872 SA---SIGHATSLPVTDTSSISTGHATPLHVTSPSSASTGHATPLPVTDTSSASTGHA-- 2926
Query: 490 SLDRTLDALSESSSSV--KTDLPQTAESRKKSGRHVTRVLVKDTAVQTPD 537
L S SS+S T LP T S +G + ++V T D
Sbjct: 2927 ---NPLHVTSPSSASTGHATPLPVTDTSSASTGHATPLPVTSLSSVSTGD 2973
Score = 30.4 bits (67), Expect = 5.4
Identities = 37/169 (21%), Positives = 71/169 (42%), Gaps = 19/169 (11%)
Query: 391 KTAGKIFRAEASTGQDAPRQAQARSWAS-QGKAASAEGDESEVSEHLSASSASAIQQDST 449
KTA + ++T + A S S Q +AS++ +++ +E S + + Q T
Sbjct: 39 KTAAPVTSTGSTTATLEGQSTAASSRTSNQDISASSQNHQTKSTETTSKAQTDTLTQMMT 98
Query: 450 SSM------------QPPSEAPMVNTVSSAYSEDFENSPSLTASEPTAHSKESLDRTLDA 497
S++ PP E + SS + S ++T + T + + + T A
Sbjct: 99 STLFSSPSVHNVMETAPPDEMT-TSFPSSVTNTLMMTSKTITMTTSTDSTLGNTEETSTA 157
Query: 498 LSESSSSVKTDLPQTAESRKKSGRHVTRVLVKDTAVQTPDPAFTYEWTK 546
+ESS+ V + + TA +S R ++DT+ + + WT+
Sbjct: 158 GTESSTPVTSAVSITAGQEGQSRTTSWRTSIQDTSASSQN-----HWTR 201
>gi|195976782 Paf1/RNA polymerase II complex component [Homo
sapiens]
Length = 710
Score = 49.7 bits (117), Expect = 9e-06
Identities = 70/317 (22%), Positives = 128/317 (40%), Gaps = 36/317 (11%)
Query: 145 QNTDKTSQNQARELPVTENNAQN-AKVSRFLKKKQAPVENISPEAPAGKERTLQTPKQKE 203
+ +K Q +E VT +N + +K L KK +E + E K RT + +K+
Sbjct: 245 EEQEKKKLTQIQESQVTSHNKERRSKRDEKLDKKSQAMEELKAEREKRKNRTAELLAKKQ 304
Query: 204 PARTFDSPDSDEEEMKVLLGSLMDSSREKNTNQGFSSANVSEEEERKLFSVPSQLRAFTV 263
P +T + DEEE + D S EK+ +S++ EEE+ + +P + + ++
Sbjct: 305 PLKTSEVYSDDEEEEE------DDKSSEKSDRSSRTSSSDEEEEKEE---IPPKSQPVSL 355
Query: 264 PS----VELSSAKPSQTSHLP------TSLAADRTLHSTRSRADYPQSHVSSDTASHTPS 313
P V LS K + H+P T + + S+ Y + ++ T
Sbjct: 356 PEELNRVRLSRHKLERWCHMPFFAKTVTGCFVRIGIGNHNSKPVYRVAEITG--VVETAK 413
Query: 314 VSITGAFSNSVSLKMGH--------VKLVSSPGRSEAETV---DEPVSEGAD-DSLDEFR 361
V G + L++ H ++ VS+ +E+E + + S G +LDE
Sbjct: 414 VYQLGGTRTNKGLQLRHGNDQRVFRLEFVSNQEFTESEFMKWKEAMFSAGMQLPTLDEIN 473
Query: 362 INILSLDGLAPAVSENSDLEQEEESAQRQKTAGKIFRAEASTGQDAPRQAQARSWASQGK 421
LS+ + D+E+ + +R + A + + + Q +A A Q K
Sbjct: 474 KKELSIKEALNYKFNDQDIEEIVKEKERFRKAPPNYAMKKT--QLLKEKAMAEDLGDQDK 531
Query: 422 AASAEGDESEVSEHLSA 438
A + +E+ E A
Sbjct: 532 AKQIQDQLNELEERAEA 548
Score = 33.9 bits (76), Expect = 0.49
Identities = 33/115 (28%), Positives = 52/115 (45%), Gaps = 20/115 (17%)
Query: 339 RSEAETVDEPVSEGADDSLDEFRINILSLDGLAPAVSENSDLEQEEE-SAQRQKTAGKIF 397
RS++E + PVS+ A A + SE SD + E + + K GK
Sbjct: 76 RSDSEEKEPPVSQPA-----------------ASSDSETSDSDDEWTFGSNKNKKKGKAR 118
Query: 398 RAE--ASTGQDAPRQAQARSWASQGKAASAEGDESEVSEHLSASSASAIQQDSTS 450
+ E + + A + A + S A S+ +E EVS+ S SS+S+ DS+S
Sbjct: 119 KIEKKGTMKKQANKTASSGSSDKDSSAESSAPEEGEVSDSDSNSSSSSSDSDSSS 173
>gi|239758038 PREDICTED: mucin 3A, cell surface associated, partial
[Homo sapiens]
Length = 909
Score = 48.9 bits (115), Expect = 1e-05
Identities = 76/398 (19%), Positives = 142/398 (35%), Gaps = 45/398 (11%)
Query: 195 TLQTPKQKEPART--FDSPDSDEEEMKVLLGSLMDSSREKNTNQGFSSANVSEEEERKLF 252
T +TP + P+ T + ++ S+ + ++ F+S+ + E
Sbjct: 3 TSETPSHRTPSFTSSITTTETPSSSTPSFTSSITTTETTSHSTPSFTSSISTTETTSH-- 60
Query: 253 SVPSQLRAFTVPSVELSSAKPSQTSHLPTSLAADRTLHSTRSRADYPQSHVSSDTASH-- 310
S PS T+ S + PS T+ + T+ + HST S Y S +++T SH
Sbjct: 61 STPSFTSLITITETT-SHSTPSYTTSITTT---ETPSHSTPS---YTTSITTTETPSHST 113
Query: 311 ---TPSVSITGAFSNSV-----SLKMGHVKLVSSPGRSEAETVDEPVSEGADDSLDEFRI 362
T S++ T S+S S++ S+P + + T+ E S S +
Sbjct: 114 PSFTSSITTTETTSHSTPSFTSSIRTTETTSYSTPSFTSSNTITETTSH----STPSYIT 169
Query: 363 NILSLDGLAPAV-SENSDLEQEEESAQRQKTAGKIFRAEASTGQDAPRQAQA----RSWA 417
+I + + + + S +S + E ++ +T P + + +
Sbjct: 170 SITTTETPSSSTPSFSSSITTTETTSHSTPGFTSSITTTETTSHSTPSFTSSITTTETTS 229
Query: 418 SQGKAASAEGDESEVSEHLSASSASAIQQDSTSSMQPPSEAPMVNTVSSAYSEDFENSPS 477
+ ++ SE H + SS S I T+S PS + T + + S
Sbjct: 230 HDTPSFTSSITTSETPSHSTPSSTSLITTTKTTSHSTPSFTSSITTTETTSHSAHSFTSS 289
Query: 478 LTASEPTAHSKESLDRTLDALSESSSSVKTDLPQTAESRKKSGRHVTRVLVKDTAVQTPD 537
+T +E T+H+ S ++ T E+ S T +
Sbjct: 290 ITTTETTSHNTRSFTSSI---------------TTTETNSHSTTSFTSSITTTETTSHST 334
Query: 538 PAFTYEWTKVASMAAMGPALGGAYVDPTPIANHVISAD 575
P+F+ T + V PTP+ +S D
Sbjct: 335 PSFSSSITTTETXXXXXXXTSETAVTPTPVTPSSLSTD 372
>gi|57164979 Treacher Collins-Franceschetti syndrome 1 isoform c
[Homo sapiens]
Length = 958
Score = 48.9 bits (115), Expect = 1e-05
Identities = 80/380 (21%), Positives = 145/380 (38%), Gaps = 59/380 (15%)
Query: 108 KLQRNLSDTESDSMTADAGLPKRADRILSGGALELASQNTDKTSQNQARELPVTENNAQN 167
K ++ + ++ES ++D+ + A ++ A+Q Q + P N +
Sbjct: 600 KAEKPMDNSESSEESSDSADSEEAPAAMT------AAQAKPALKIPQTKACPKKTNTTAS 653
Query: 168 AKVSRFLKKKQAPVENISPEAPAGKERTLQTPKQKEPARTFDSPDSDEEEMKVLLGSLMD 227
AKV+ QAP + + +PAG + Q+ + S +SD EE K L +
Sbjct: 654 AKVAPVRVGTQAPRKAGTATSPAGSSPAVAGGTQRPAEDSSSSEESDSEEEKTGLAVTVG 713
Query: 228 SSREKNTNQGFSSANVSEEEERKLFSVPSQLRAFTVPSVELSSAKPSQTSHLPTSLAADR 287
++ +A+V V L T P + P +T T + A++
Sbjct: 714 QAKSVGKGLQVKAASV---------PVKGSLGQGTAPVL------PGKTGPTVTQVKAEK 758
Query: 288 TLHSTRSRADYPQSHVSSDTASHTPSVSITGAFSNSVSLKMGHVK-LVSSPGR---SEAE 343
S S + ++ A SV T A +N + + K +S+PG+ + A+
Sbjct: 759 QEDSESSEEESDSEEAAASPAQVKTSVKKTQAKANPAAARAPSAKGTISAPGKVVTAAAQ 818
Query: 344 TVDEPVSEGADDSLDEFRINIL-----SLDGLAPAVS-----------------ENSDLE 381
S+ + +L S+ + AV+ E SD E
Sbjct: 819 AKQRSPSKVKPPVRNPQNSTVLARGPASVPSVGKAVATAAQAQTGPEEDSGSSEEESDSE 878
Query: 382 QEEESAQRQKTAGKI--FRAEASTGQDAPRQAQA--------RSWASQGKA--ASAEGDE 429
+E E+ + K +GK RA + +++PR+ A S A GK + + +E
Sbjct: 879 EEAETLAQVKPSGKTHQIRAALAPAKESPRKGAAPTPPGKTGPSAAQAGKQDDSGSSSEE 938
Query: 430 SEVSEHLSASSASAIQQDST 449
S+ A+ SA Q+S+
Sbjct: 939 SDSDGEAPAAVTSAQDQESS 958
Score = 39.7 bits (91), Expect = 0.009
Identities = 74/365 (20%), Positives = 141/365 (38%), Gaps = 34/365 (9%)
Query: 113 LSDTESDSMTADAGLPKRADRILSGGALELASQNTDKTSQNQARELPVTENNAQNAKVSR 172
+S+TE + G + + S G + +S++T +S E + AQ S
Sbjct: 170 VSETEEEGSVPAFGAAAKPGMV-SAGQADSSSEDTSSSSDETDVEGKPSVKPAQVKASS- 227
Query: 173 FLKKKQAPVENISPEAPAGKERTLQTPKQK----EPARTFDSPDSDEEEMKVLLGSLMDS 228
+ K++P +P AP GK + TP+ K PA+ P+ + E S S
Sbjct: 228 -VSTKESPARKAAP-AP-GKVGDV-TPQVKGGALPPAKRAKKPEEESES------SEEGS 277
Query: 229 SREKNTNQGFSSANVSEEEERKLFSVPSQLRAFTVPSVELSSAKPSQTSHLPTSLAADRT 288
E+ G S + E+ ++ + + + P + A P + + + A +
Sbjct: 278 ESEEEAPAGTRSQVKASEKILQVRAASAPAKG--TPGKGATPAPPGKAGAVASQTKAGKP 335
Query: 289 LHSTRSRADYPQSHVSSDTASHTPSVSITGAFSNSVSLKMGHVKLVSSPGRSEAETVDEP 348
+ S S SSD+ TP+ S K V S+P + P
Sbjct: 336 EEDSES-----SSEESSDSEEETPAAK--ALLQAKASGKTSQVGAASAPAKESPRKGAAP 388
Query: 349 VSEG-ADDSLDEFRINILSLDGLAPAVSENSDLEQEEESAQRQKTAGKIFRAEASTGQDA 407
G ++ + + D + + SE SD E+E + + RA ++ +++
Sbjct: 389 APPGKTGPAVAKAQAGKREED--SQSSSEESDSEEEAPAQAKPSGKAPQVRAASAPAKES 446
Query: 408 PRQAQARSWASQGKAASA------EGDESEVSEHLSASSASAIQQDSTSSMQPPSEAPMV 461
PR+ A + + A+A + ++S S S S A+ + + ++P ++P V
Sbjct: 447 PRKGAAPAPPRKTGPAAAQVQVGKQEEDSRSSSEESDSDREALAAMNAAQVKPLGKSPQV 506
Query: 462 NTVSS 466
S+
Sbjct: 507 KPAST 511
>gi|239758058 PREDICTED: similar to mucin, partial [Homo sapiens]
Length = 967
Score = 48.5 bits (114), Expect = 2e-05
Identities = 82/418 (19%), Positives = 144/418 (34%), Gaps = 50/418 (11%)
Query: 185 SPEAPAGKERTLQTPKQKEP--ARTFDSPDSDEEEMKVLLGSLMDSSREKNTNQGFSSAN 242
SP + T +TP P + + + ++ S+ + GF+S+
Sbjct: 34 SPPSFTSSSTTTETPSHSTPGFSSSIATTETTSHSTASFTSSIATTETMSQNIPGFTSSI 93
Query: 243 VSEEEERKLFSVPSQLRAFTVPSVELSSAKPS---------QTSHLPTSLAA-----DRT 288
+ E S PS + T S + PS TSH S + + T
Sbjct: 94 ATTEITSH--STPSFTSSITTTETT-SQSSPSFTSLITITGSTSHSTASFTSSITTTETT 150
Query: 289 LHSTRS--------------RADYPQSHVSSDTASHTPSVSITGAFSNSVSLKMGHVKLV 334
HSTRS Y S +S+T SHT S T + + S + L
Sbjct: 151 SHSTRSITSSITTTKRTSHSSLSYTSSIATSETPSHTVP-SFTSLITTTESTSHSNPSLT 209
Query: 335 SSPGRSEAETVDEPVSEGADDSLDEFRINILSLDGLAPAVSENSDLEQEEESAQRQKTAG 394
S+ +E + P+ + +++ + S L +E + L + T
Sbjct: 210 SAITTTETRSHSPPIFTSSITTIETTSHSTPSFTSLM-TTTETTSLSPPAFTFSISTTET 268
Query: 395 KIFRAEASTGQDAPRQAQARSWASQGKAASAEGDES-------------EVSEHLSASSA 441
+ T A + + S S + S E + H + S
Sbjct: 269 NSHSPPSFTSSIATTETPSHSPPSFTSLITTTESTSHSPLSFTSVITTTESTSHSTPSFT 328
Query: 442 SAIQQDSTSSMQPPSEAPMVNTVSSAYSEDFENSPSLTASEPTAHSKESLDRTL--DALS 499
S+I T+S PPS ++ T + + + +TA+E T+HS S + ++
Sbjct: 329 SSIATTETTSHTPPSFTSLITTTETPSHSNPSFTSLITATESTSHSPPSFTSAIATTGIT 388
Query: 500 ESSSSVKTDLPQTAESRKKSGRHVTRVLVKDTAVQTPDPAFTYEWTKVASMAAMGPAL 557
S+ + T L T +S S T + + P+F+ T + + P+L
Sbjct: 389 SHSTPIFTSLIATTDSTSHSTPSFTSSITSTETISHSTPSFSSLITATKTTSHSTPSL 446
Score = 37.0 bits (84), Expect = 0.058
Identities = 57/279 (20%), Positives = 99/279 (35%), Gaps = 29/279 (10%)
Query: 233 NTNQGFSSA-----NVSEEEERKLFSVPS-QLRAFTVPSVELSSAKPSQTSHLPTSLAAD 286
++ GFSS+ S R F++ + + + P L+ A TSH SL +
Sbjct: 563 HSTPGFSSSIATSKTTSTSPPRFTFAIATTKTTLHSTPRFTLAIASTKTTSHSTPSLTSL 622
Query: 287 RTLHSTRSRADYPQSHVSSDTASHTPSVSITGAFSNSVSLKMGHVKLVSSPGRSEAETVD 346
T T S T S T S++ +G S+S + + S S T
Sbjct: 623 ITTIETTSHC----------TPSLTSSITTSGTISHSTPSFTSLITITESTSHS---TTS 669
Query: 347 EPVSEGADDSLDEFRINILSLDGLAPAVSENS-DLEQEEESAQRQKTAGKIFRAEASTGQ 405
P S ++ + SL +S ++ + + + F +T +
Sbjct: 670 FPSSITTTETTSHSTPSFTSLIATTEIISHSTPSYTSSIATTETPSHSTPSFPFSITTTE 729
Query: 406 DAPRQAQARSWASQGKAASAEGDESEVSEHLSASSASAIQQDSTSSMQPPSEAPMVNTVS 465
P + + A +E H AS+I T+S PP ++ T
Sbjct: 730 TIPHSTPSLNSAIT---------TTETMSHSIPGFASSITTSETTSPFPPRFTSLITTTK 780
Query: 466 SAYSEDFENSPSLTASEPTAHSKESLDRTLDALSESSSS 504
+ + SLT++E T+HS S + + +S S
Sbjct: 781 TTSHSPPSFTASLTSTEATSHSPLSFTSVIASTKITSQS 819
Score = 33.1 bits (74), Expect = 0.83
Identities = 17/62 (27%), Positives = 30/62 (48%)
Query: 430 SEVSEHLSASSASAIQQDSTSSMQPPSEAPMVNTVSSAYSEDFENSPSLTASEPTAHSKE 489
+E++ H + S S+I T+S PS ++ S + S+T +E T+HS
Sbjct: 881 TEITSHSTPSFTSSITTMETTSRSSPSFTSLITITGSTSHSTASFTSSITTTETTSHSTP 940
Query: 490 SL 491
S+
Sbjct: 941 SI 942
>gi|217330641 IWS1 homolog [Homo sapiens]
Length = 819
Score = 47.8 bits (112), Expect = 3e-05
Identities = 82/425 (19%), Positives = 158/425 (37%), Gaps = 59/425 (13%)
Query: 109 LQRNLSDTESDSM----TADAGLPKRADRILSGGALELASQNTDKTSQNQARELPVTENN 164
L N SD+ES+ + +D+ +RA+ S E +Q+ + + R+LP +++
Sbjct: 75 LNLNASDSESEELHRQKDSDSESEERAEPPASDSENEDVNQHGSDSESEETRKLPGSDSE 134
Query: 165 AQNAKVSRFLKKKQAPVENISP-EAPAGKERTLQTPKQKEPARTFDSPDSDEEEMKVLLG 223
+ L + EN + PA + K SP SD E L
Sbjct: 135 NEE-----LLNGHASDSENEDVGKHPASDSEIEELQK---------SPASDSETEDALKP 180
Query: 224 SLMDSSREKNTNQGFSSANVSEEEERKLFSVPSQLRAFTVPSVELSSAKPSQTSHLPTSL 283
+ DS E+ S + E + ++ S+ +P ++S ++ + S
Sbjct: 181 QISDSESEEPPRHQASDSENEEPPKPRMSDSESE----ELPKPQVSDSESEEPPRHQASD 236
Query: 284 AADRTLHSTR---SRADYPQSHVSSDTASHTPSVSITGAFSNSVSLKMGHVKLVSSPGRS 340
+ + L R S ++ P H +SD+ + + P S
Sbjct: 237 SENEELPKPRISDSESEDPPRHQASDSENEE----------------------LPKPRIS 274
Query: 341 EAETVDEPVSEGADDSLDEF-RINILSLDGLAPAVSENSDLEQEEESAQRQKTAGKIFRA 399
++E+ D P ++ +D +E + + + P SD E E+ S +QK
Sbjct: 275 DSESEDPPRNQASDSENEELPKPRVSDSESEGPQKGPASDSETEDASRHKQKPESDDDSD 334
Query: 400 EASTGQDAPRQAQARSWASQGKAASAEGDESEVSEHLSASSASAIQQDSTSSMQPPSEAP 459
+ G+D Q + S +SE EH Q+ + + E
Sbjct: 335 RENKGEDTEMQNDSFHSDSHMDRKKFHSSDSEEEEHKK-------QKMDSDEDEKEGEEE 387
Query: 460 MVNTVSSAYSEDFENSPSLTASEPTAHSKESLDRTLDALSESSSSVKTDLPQTAESRKKS 519
V +A D E+ +A + S ++ D DA+S+ S K + ++S +++
Sbjct: 388 KVAKRKAAVLSDSEDEEKASAKKSRVVS-DADDSDSDAVSDKSG--KREKTIASDSEEEA 444
Query: 520 GRHVT 524
G+ ++
Sbjct: 445 GKELS 449
>gi|34482047 adaptor-related protein complex 3, beta 2 subunit [Homo
sapiens]
Length = 1082
Score = 47.0 bits (110), Expect = 6e-05
Identities = 43/165 (26%), Positives = 71/165 (43%), Gaps = 10/165 (6%)
Query: 347 EPVSEGADDSLDEFRINILSLDGLAPAVSENSDLEQEEESAQRQKTAGKIFRAEASTGQD 406
+P SE DS S G + + S+N D +++EE + ++ + T +
Sbjct: 694 DPESESESDSKSSSE----SGSGESSSESDNEDQDEDEEKGRGSESEQSEEDGKRKTKKK 749
Query: 407 APRQAQARSWASQGKAASAEGDESEVSEHLSASSASAIQQDSTSSMQPPS--EAPMVNTV 464
P + S + +G +S+ ESE++ S S ++ S S PPS AP +
Sbjct: 750 VPERKGEASSSDEGSDSSSSSSESEMT---SESEEEQLEPASWSRKTPPSSKSAPATKEI 806
Query: 465 SSAYSEDFENSPSLTASEPTAHSKESLDRTLDALSESSSSVKTDL 509
S EDF PS+ P A SL L+ L+ + S++ L
Sbjct: 807 SLLDLEDF-TPPSVQPVSPPAIVSTSLAADLEGLTLTDSTLVPSL 850
>gi|8923040 CDKN2A interacting protein [Homo sapiens]
Length = 580
Score = 45.1 bits (105), Expect = 2e-04
Identities = 75/307 (24%), Positives = 119/307 (38%), Gaps = 57/307 (18%)
Query: 232 KNTNQGFSSANVSEEE-------ERKLFSVPSQLRAFTVPSVELSSAKPSQTSHLPTSLA 284
K +G SS+N EE E K S Q A T E +SA+ +S S
Sbjct: 124 KVKKRGISSSNEGVEEPSKKRVIEGKNSSAVEQDHAKTSAKTERASAQQENSSTCIGSAI 183
Query: 285 ADRTLHSTRSRADYPQSHVSSDTASHTPSVSITGAFSNSVSLKMGHVKLVSSPGRSEAET 344
+ +S RS Q+ +SD S++ S+SVS + V++ G +A
Sbjct: 184 KSESGNSARSSGISSQNSSTSDGDR-----SVSSQSSSSVSSQ------VTTAGSGKASE 232
Query: 345 VDEPVSEGADDSLDEFRINILSLDGLAPAVSENSDLEQEEESAQRQKTAGKIFRAEASTG 404
+ P G+ + + ++ NS + Q +S Q+
Sbjct: 233 AEAPDKHGSASFVSLLKSSV------------NSHMTQSTDSRQQS-------------- 266
Query: 405 QDAPRQAQARSWASQGKAASAEGDESEVSEHLSASSASAIQQDSTSSMQPPSEAPMVNTV 464
+P+++ A +G +ASA SE+ L SS S+ + S +P SE
Sbjct: 267 -GSPKKS-----ALEGSSASASQSSSEIEVPLLGSSGSSEVELPLLSSKPSSETASSGLT 320
Query: 465 SSAYSED------FENSPSLTASEPTAHSKESLDRTLDALSESSSSVKTDLPQTAESRKK 518
S SE +NS S S T S S + +L S+S+S V L + S +
Sbjct: 321 SKTSSEASVSSSVAKNSSSSGTSLLTPKSSSSTNTSL-LTSKSTSQVAASLLASKSSSQT 379
Query: 519 SGRHVTR 525
SG V++
Sbjct: 380 SGSLVSK 386
>gi|153945728 microtubule-associated protein 1B [Homo sapiens]
Length = 2468
Score = 45.1 bits (105), Expect = 2e-04
Identities = 79/413 (19%), Positives = 158/413 (38%), Gaps = 54/413 (13%)
Query: 155 ARELPVTENNAQNAKVSRFLKKKQAPVENISPEAPAGKERTLQTPKQKEPARTFDSPDSD 214
++ P + + A+ ++++K+ V + A + ++ + ++ D D
Sbjct: 967 SKHSPTEDEESAKAEADAYIREKRESVASGDDRAEEDMDEAIEKGEAEQSEEEADEEDKA 1026
Query: 215 EEEMKVLLGSLMDSSREKNTNQGFSSANVSE-------EEERKLFSVPSQLRAFTVPSVE 267
E+ + + EK + + A V + EE+ + P++ P E
Sbjct: 1027 EDAREE------EYEPEKMEAEDYVMAVVDKAAEAGGAEEQYGFLTTPTKQLGAQSPGRE 1080
Query: 268 LSSAKPSQTSHLPTSLAADRTLHSTRSRADYPQSHVSSDTASHTPSVSITGAFSNSVSLK 327
+S+ +T LP ++ T +R D P+ + T+ +T S + + +
Sbjct: 1081 PASSIHDET--LPGGSESEATASDEENREDQPEEFTA--TSGYTQSTIEISSEPTPMD-E 1135
Query: 328 MGHVKLVSSPGRSEAETVDEPVSEGADDSLDEFRINILSLDGLAPAVSENSDLEQEEESA 387
M + V S + ET + P E + + ++ ++ S + PA + + L E +
Sbjct: 1136 MSTPRDVMSDETNNEET-ESPSQEFVN--ITKYESSLYSQEYSKPA--DVTPLNGFSEGS 1190
Query: 388 QRQKTAGKIFRAEAST--------GQDAPRQAQARSWASQGKAASAEGDESEVSEHLSAS 439
+ T GK + A AST R A ++ S+ KA++ ++ + +SA
Sbjct: 1191 KTDATDGKDYNASASTISPPSSMEEDKFSRSALRDAYCSEVKASTT----LDIKDSISAV 1246
Query: 440 SASAIQQDSTSSMQPPSEAPMVNTVSSAYSEDFEN----------------SPSLTASEP 483
S+ + + S+ P +P+ T S +F SP +T
Sbjct: 1247 SSEKVSPSKSPSLSPSPPSPLEKTPLGERSVNFSLTPNEIKVSAEAEVAPVSPEVTQEVV 1306
Query: 484 TAHSKESLDRTLDALSESSS---SVKTDLPQTAESRKKSGRHVTRVLVKDTAV 533
H D+TL+ +S S S S + + +KS T V+ K AV
Sbjct: 1307 EEHCASPEDKTLEVVSPSQSVTGSAGHTPYYQSPTDEKSSHLPTEVIEKPPAV 1359
Score = 32.7 bits (73), Expect = 1.1
Identities = 26/104 (25%), Positives = 44/104 (42%), Gaps = 5/104 (4%)
Query: 406 DAPRQAQARSWASQGKAASAEGDESEVSEHLSASSASAIQQDSTSSMQPPSEAPMVNTVS 465
+ P Q + + E S S H + AS +Q+D+ S + PP + + +++
Sbjct: 1707 EEPSYTQDNDLSELISVSQVEASPSTSSAHTPSQIASPLQEDTLSDVAPPRDMSLYASLT 1766
Query: 466 SAYSEDFEN---SPSLTASEPTAHSKESLDRTLDALSESSSSVK 506
S + E SP S T +ES S+S+S+VK
Sbjct: 1767 SEKVQSLEGEKLSPKSDISPLT--PRESSPLYSPTFSDSTSAVK 1808
>gi|22749117 hypothetical protein LOC152405 [Homo sapiens]
Length = 536
Score = 44.7 bits (104), Expect = 3e-04
Identities = 68/291 (23%), Positives = 111/291 (38%), Gaps = 47/291 (16%)
Query: 260 AFTVPSVELSSAKPSQTSHLPTSLAADRTLHSTRSRADYPQSHVSSDTASHTPSVSITGA 319
A P S A PS H D+ + R ++ ++ TA PS + +
Sbjct: 8 ALAEPLKHESPAAPSSAGHTKGQEEDDQKNQAERKADNHTAHRIADQTALRVPSQAESSI 67
Query: 320 FS---NSVSLKMGHVKLVSSPGRS--EAETVDEPVSEGADDSLDEF-------------- 360
FS N V+ + GH S+PG++ A + ADD +++
Sbjct: 68 FSQATNGVAEQNGH----STPGQAGRRASNPADVSDLRADDQVNQTPSEQTKGKASSQAN 123
Query: 361 RINILSLDGLAPAVSENSDLEQEEESAQRQ---KTAGKI-FRAEASTGQDAPRQAQARSW 416
+ DG ++E EQ E Q +T+G+I R + Q RQ R
Sbjct: 124 NVQHEQSDGQVSGLTEERTAEQTERRLPTQAERRTSGQIDGRLAMPSDQRGSRQTDHRMA 183
Query: 417 ASQGKAASAEGD-------ESEVSEHLS------ASSASAIQQDSTSSMQPPSEAPMVNT 463
+ AS + D E SE ++ + ++Q DS SS+ P ++P V
Sbjct: 184 GQSERRASEQMDRRMSGEAERRTSEQITHRLSKLSERRPSVQIDSGSSV-PSDQSPSVQ- 241
Query: 464 VSSAYSEDFENSPSL-----TASEPTAHSKESLDRTLDALSESSSSVKTDL 509
+ S S + PS+ + + S E D L L++ +S +TDL
Sbjct: 242 IDSGSSVPSDQRPSVQIDRRMSGKVRRRSSEKTDYRLAGLADPGTSEQTDL 292
>gi|239752529 PREDICTED: similar to mucin [Homo sapiens]
Length = 594
Score = 44.3 bits (103), Expect = 4e-04
Identities = 66/309 (21%), Positives = 113/309 (36%), Gaps = 46/309 (14%)
Query: 254 VPSQLRAFTVPSVELSSAKPSQTSHLPTSLAADRTLHSTRSRAD--YPQSHVSSDTASH- 310
+P + + TVPS TSH SL + T TRS + + S + +T SH
Sbjct: 8 IPHETPSHTVPSFTSLITTTDSTSHSNPSLTSAITTTETRSHSPPIFTSSITTIETTSHS 67
Query: 311 TPSVSITGAFSNSVSLKMGHVKLVSSPGRSEAETVDEPVSEGADDSLDEFRINILSLDGL 370
TPS + + + SL SP A T +E S F +I + +
Sbjct: 68 TPSFTSLMTTTETTSL---------SP---PAFTFSISTTETNSHSPPSFTSSIATTETP 115
Query: 371 APAVSENSDLEQEEESAQRQKTAGKIFRAEASTGQDAPRQAQARSWASQGKAASAEGDES 430
+ + + L ES + F + +T +
Sbjct: 116 SHSPPSFTSLITTTESTSHSPLS---FTSVITT--------------------------T 146
Query: 431 EVSEHLSASSASAIQQDSTSSMQPPSEAPMVNTVSSAYSEDFENSPSLTASEPTAHSKES 490
E + H + S S+I T+S PPS ++ T + + + +TA+E T+HS S
Sbjct: 147 ESTSHSTPSFTSSIATTETTSHTPPSFTSLITTTETPSHSNPSFTSLITATESTSHSPPS 206
Query: 491 LDRTL--DALSESSSSVKTDLPQTAESRKKSGRHVTRVLVKDTAVQTPDPAFTYEWTKVA 548
+ ++ S+ + T L T +S S T + + P+F+ T
Sbjct: 207 FTSAIATTGITSHSTPIFTSLIATTDSTSHSTPSFTSSITSTETISHSTPSFSSLITATK 266
Query: 549 SMAAMGPAL 557
+ + P+L
Sbjct: 267 TTSHSTPSL 275
Score = 38.1 bits (87), Expect = 0.026
Identities = 69/317 (21%), Positives = 115/317 (36%), Gaps = 40/317 (12%)
Query: 253 SVPSQLRAFTVPSVELSSAKPSQTSHLPTSLAADRTLHSTRSRADYPQSHVSSDTASH-T 311
S PS L + + S + PS TS + T + T HST S S ++ T SH T
Sbjct: 287 STPS-LTSLVTSTETASHSTPSFTSLITT---IEATSHSTPSLTS---SITTTGTTSHST 339
Query: 312 PSVSITGAFSNSVSLKMGHVKLVSSPGRSEAETVDEPVSEGADDSLDEFRINILSLDGLA 371
PS + + S S S+P + A T E +S S+ F +I+S
Sbjct: 340 PSFTYLTTITESTSH--------STPSLTSAITTTETMSH----SILGFTPSIIS----- 382
Query: 372 PAVSENSDLEQEEESAQRQKTAGKIFRAEASTGQDAPRQAQARSWASQGKAASAEG---- 427
P+ L E+ + F + +T Q A + + A A +
Sbjct: 383 PSTPSYISLIATTETPSHSTPS---FPSSITTTQSASHSTPSLTSAISTTEAMSHSIPVF 439
Query: 428 ----DESEVSEHLSASSASAIQQDSTSSMQPPSEAPMVNTVSSAYSEDFENSPSLTASEP 483
+E + HL S I T+S PPS ++ + + + S+ +E
Sbjct: 440 TSLITTTETTSHLPPRFTSLITTTKTTSHSPPSFTALITSTKTTSHSTPSFTSSIATTET 499
Query: 484 TAHSKESL---DRTLDALSESSSSVKTDLPQTAESRKKSGRHVTRVLVKDTAVQTPDPAF 540
T+HS S T + S S+ + + + + R + T + + P F
Sbjct: 500 TSHSPPSFTSSSTTTETHSHSTPGFSSSIATSKTTSTSPPRFTFAIATTKTTLHS-TPRF 558
Query: 541 TYEWTKVASMAAMGPAL 557
T + + P+L
Sbjct: 559 TLAIASTKTTSHSTPSL 575
Score = 36.2 bits (82), Expect = 0.098
Identities = 81/411 (19%), Positives = 140/411 (34%), Gaps = 47/411 (11%)
Query: 185 SPEAPAGKERTLQTPKQKEPARTFDSPDSDEEEMKVLLGSLMDSSREKNTNQGFSSANVS 244
SP T++T P+ T ++ + + S+ E N++ S +
Sbjct: 50 SPPIFTSSITTIETTSHSTPSFTSLMTTTETTSLSPPAFTFSISTTETNSHSPPSFTSSI 109
Query: 245 EEEERKLFSVPSQLRAFTVPSVELSSAKPSQTSHLPTSLAADRTLHSTRSRADYPQSHVS 304
E S PS FT S S S + T HST S + S +
Sbjct: 110 ATTETPSHSPPS----FTSLITTTESTSHSPLSFTSVITTTESTSHSTPS---FTSSIAT 162
Query: 305 SDTASHTPSVSITGAFSNSVSLKMGHVKLVSSPGRSEAETVDEPVSEGA-------DDSL 357
++T SHTP S T + + + + S +E+ + P A S
Sbjct: 163 TETTSHTPP-SFTSLITTTETPSHSNPSFTSLITATESTSHSPPSFTSAIATTGITSHST 221
Query: 358 DEFRINILSLDGLAPAV-SENSDLEQEEESAQRQKTAGKIFRAEASTGQDAPRQAQARSW 416
F I + D + + S S + E + + + A +T P +
Sbjct: 222 PIFTSLIATTDSTSHSTPSFTSSITSTETISHSTPSFSSLITATKTTSHSTPSLTSLITT 281
Query: 417 ASQGKAASAEGDESEVSEHLSASSASAIQQDSTSSMQPPSEAPMVNTVSSAYSEDFENSP 476
+ + H + S S + T+S PS ++ T+ + +
Sbjct: 282 TN--------------TSHSTPSLTSLVTSTETASHSTPSFTSLITTIEATSHSTPSLTS 327
Query: 477 SLTASEPTAHSKES---LDRTLDALSESSSSVKTDLPQTAESRKKSGRHVTRVLVKDT-- 531
S+T + T+HS S L ++ S S+ S+ T T E+ S T ++ +
Sbjct: 328 SITTTGTTSHSTPSFTYLTTITESTSHSTPSL-TSAITTTETMSHSILGFTPSIISPSTP 386
Query: 532 -------AVQTPD---PAFTYEWTKVASMAAMGPALGGAYVDPTPIANHVI 572
+TP P+F T S + P+L A + T +H I
Sbjct: 387 SYISLIATTETPSHSTPSFPSSITTTQSASHSTPSLTSA-ISTTEAMSHSI 436
Score = 35.8 bits (81), Expect = 0.13
Identities = 35/164 (21%), Positives = 68/164 (41%), Gaps = 9/164 (5%)
Query: 431 EVSEHLSASSASAIQQDSTSSMQPPSEAPMVNTVSSAYSEDFENSPSLTASEPTAHSK-- 488
E + H + S S + T+S+ PP+ ++T + + S+ +E +HS
Sbjct: 62 ETTSHSTPSFTSLMTTTETTSLSPPAFTFSISTTETNSHSPPSFTSSIATTETPSHSPPS 121
Query: 489 -ESLDRTLDALSESSSSVKTDLPQTAESRKKSGRHVTRVLVKDTAVQTPDPAFTYEWTKV 547
SL T ++ S S S + + T + + + + +T TP P+FT T
Sbjct: 122 FTSLITTTESTSHSPLSFTSVITTTESTSHSTPSFTSSIATTETTSHTP-PSFTSLITTT 180
Query: 548 ASMAAMGPALGGAYVDPTPIANH----VISADAIEALTAYSPAV 587
+ + P+ + + T +H SA A +T++S +
Sbjct: 181 ETPSHSNPSF-TSLITATESTSHSPPSFTSAIATTGITSHSTPI 223
>gi|239740827 PREDICTED: hypothetical protein XP_002344067 [Homo
sapiens]
Length = 1521
Score = 43.1 bits (100), Expect = 8e-04
Identities = 59/272 (21%), Positives = 99/272 (36%), Gaps = 9/272 (3%)
Query: 270 SAKPSQTSHLPTSLAADRTLHSTRSRADYPQSHVSSDTA-----SHTPSVSITGAFSNSV 324
S S+T+ + T+ ++RT+ ST S S+T S T +VSITG+ + V
Sbjct: 647 STTDSETTMVSTT-GSERTITSTEGSETTTVSATGSETTVSTEGSGTTTVSITGSETTKV 705
Query: 325 SLKMGHVKLVSSPGRSEAETVDEPVSEGADDSLDEFRINILSLDGLAPAVSENSDLEQEE 384
S + S+ G SE T SE S + S +G + + E
Sbjct: 706 STTGSETTITSTEG-SEITTASITGSETTTASTEGSETTTASTEGSETTSASTTGSETTT 764
Query: 385 ES-AQRQKTAGKIFRAEASTGQDAPRQAQARSWASQGKAASAEGDESEVSEHLSASSASA 443
S + T I +E + + S AS K + + SE + + +S +
Sbjct: 765 ASTTSSETTMASIMGSETTMASTIGSETTKVSTAS-SKMTTVFTENSETTIASTTASETT 823
Query: 444 IQQDSTSSMQPPSEAPMVNTVSSAYSEDFENSPSLTASEPTAHSKESLDRTLDALSESSS 503
+ S P S A T +++ + S SE T S ES + T S +
Sbjct: 824 TVSTAGSETIPASTAGSETTTTTSTEGSETTTASTEGSETTTASTESSETTTATTIGSET 883
Query: 504 SVKTDLPQTAESRKKSGRHVTRVLVKDTAVQT 535
+ + + G T + + + T
Sbjct: 884 TTASTEGSETTTTSTEGSETTTASTEGSEITT 915
Score = 35.8 bits (81), Expect = 0.13
Identities = 83/385 (21%), Positives = 139/385 (36%), Gaps = 69/385 (17%)
Query: 207 TFDSPDSDEEEMKVLLGSLMDSSREKNTNQGFSSANVSEEEERKLFSVPSQ-LRAFTVPS 265
T S E M +GS +++ + + + E +F+ S+ +RA TV S
Sbjct: 284 TAASTTGSEPTMASTMGS--ETTMASTIGPETTKVSTASSEVTTVFAAGSETIRASTVGS 341
Query: 266 ----VELSSAKPSQTSHLPTSLAADRTLHS--TRSRADYPQSHVSSDTASHTPSVSITGA 319
V + ++ + S + + + D T S T + + ++ +S S +VS TG+
Sbjct: 342 ETTTVSTTGSETTTASIMGSETSTDSTTGSETTTASTEGSETTTASTEGSEATTVSTTGS 401
Query: 320 FSNSVSLKMGHVKLVSSPGRSEAETVDEPVSEGADDSLDEFRINILSLDGLAPAVSENSD 379
+ +VS+ + G SE V V E S + I I S SE +
Sbjct: 402 ETTTVSITDSETTTTCTEG-SEMTAVSTTVFETTTASTEGSEITIASTSD-----SETTT 455
Query: 380 LEQEEESAQRQKTAGKIFRAEASTGQDAPRQAQ-----------------ARSWASQGKA 422
E TAG + +TG + + A + S+ A
Sbjct: 456 ASTEGSETTTVTTAGSETKTAYTTGSETTTASNTGLETTTVFTIGSDTTTASTEGSETTA 515
Query: 423 ASAEGDE-----SEVSEHLSASSA-------SAIQQDSTSSMQPPSEAPMVNTV------ 464
SA G E +E SE+ + S+ S ++T++ SE V+T
Sbjct: 516 VSATGSEMTTVSTEGSENTTVSTTGSETTTVSTTGLETTTTSTEGSEMTTVSTTGAETTT 575
Query: 465 -----------SSAYSE-------DFENSPSLTASEPTAHSKESLDRTLDALSESSSSVK 506
S+A SE D EN+ + TA T + + T A S +SS
Sbjct: 576 DSTEGSGTTAASTAGSETTTVSTADSENTTASTADSETTSASTTGSETTTA-STTSSETT 634
Query: 507 TDLPQTAESRKKSGRHVTRVLVKDT 531
T + +E+ S +V T
Sbjct: 635 TASTEGSETTTVSTTDSETTMVSTT 659
Score = 34.3 bits (77), Expect = 0.37
Identities = 49/260 (18%), Positives = 88/260 (33%), Gaps = 11/260 (4%)
Query: 262 TVPSVELSSAKPSQTSHLPTSLAADRTLHSTRSRADYPQSHVSSDTASHTPSVSITGAFS 321
TV S+ + T+ T+ + +T + ++ S T S T VSI+G+
Sbjct: 6 TVAPAAGSNTTTASTTGSETTTILIKASETTTASTAGSETTTPSPTGSQTTIVSISGSEI 65
Query: 322 NSVSLKMGHVKLVSSPG--------RSEAETVDEPVSEGADDSLDEFRINILSLDGLAPA 373
+ S VSS G TV SE S+ ++S G
Sbjct: 66 TTTSTAGSENTTVSSAGSGTTTASMAGSETTVSTAGSETTTVSITGTETTMVSAMGSETT 125
Query: 374 VSENSDLEQEEES-AQRQKTAGKIFRAEASTGQDAPRQAQARSWASQGKAASAEGDESEV 432
+ + E S A + T +E +T A + A S +
Sbjct: 126 TNSTTSSETTVTSTAGSETTTVSTVGSETTTAYTADSETTAASTTGSEMTTVFTAGSETI 185
Query: 433 SEHLSASSASAIQQDSTSSMQPPSEAPMVNTVSSAYSEDFENSPSLTASEPTAHSKESLD 492
+ + S + + + + + T S+A+SE + S SE T S +
Sbjct: 186 TPSTAGSETTTVSTAGSETTTVSTTGSETTTASTAHSE--TTAASTMGSETTKVSTAGSE 243
Query: 493 RTLDALSESSSSVKTDLPQT 512
T+ +++ T+ +T
Sbjct: 244 TTVSTAGSETTAASTEDSET 263
>gi|148596949 nucleolar and coiled-body phosphoprotein 1 [Homo
sapiens]
Length = 699
Score = 42.7 bits (99), Expect = 0.001
Identities = 83/422 (19%), Positives = 155/422 (36%), Gaps = 82/422 (19%)
Query: 80 RPPTTASRIRANA-ALMKLAQLETRIMNRKLQRNLSDTESDSMTAD------AGLPKRA- 131
+P T ++A A K A+ +I N K + S + S S + D A PK+
Sbjct: 184 KPKITPVTVKAQTKAPPKPARAAPKIANGKAASSSSSSSSSSSSDDSEEEKAAATPKKTV 243
Query: 132 --DRILSGGALELASQNTDKTSQNQARELPVTENNAQNAKVSRFLKKKQAPVENISPEAP 189
++++ ++ A+ T K+S ++ ++ + + + +K K P ++ P +
Sbjct: 244 PKKQVVAKAPVKAATTPTRKSSSSE------DSSSDEEEEQKKPMKNKPGPYSSVPPPSA 297
Query: 190 AGKERTLQTPKQKEPARTFDSPDSDEEEMKVLLGSLMDSSREKNTNQGFSSANVSEEEER 249
+++L T K+ +S E DSS E ++ S EEE+
Sbjct: 298 PPPKKSLGTQPPKKAVEKQQPVESSE-----------DSSDESDS---------SSEEEK 337
Query: 250 KLFSVPSQLRAFTVPSVELSSAKPSQTSHLPTSLAADRTLHSTRSRADYPQSHVSSDTAS 309
K T V ++ KP P AA+ S +D S S D +
Sbjct: 338 K---------PPTKAVVSKATTKPP-----PAKKAAE-------SSSDSSDSDSSEDDEA 376
Query: 310 HTPSVSITGAFSNSVSLKMGHVKLVSSPGRSEAETVDEPVSEGADDSLDEFRINILSLDG 369
+ T SN ++ SP A +PV G
Sbjct: 377 PSKPAGTTKNSSNKPAVT------TKSPAVKPAAAPKQPVGGGQK--------------- 415
Query: 370 LAPAVSENSDLEQEEESAQRQKTAGKIFRAEASTGQDAPRQAQARSWASQGKAASAEGDE 429
L +++S E+E S++ +KT + + A A+ + +S++ D
Sbjct: 416 LLTRKADSSSSEEESSSSEEEKTKKMVATTKPKATAKAALSLPAKQAPQGSRDSSSDSDS 475
Query: 430 SEVSEHLSASSASAIQQDSTSSMQPPSEAPMVNTVSSAYSEDFENSPSLTASEPTAHSKE 489
S E +S SA+++ Q + + +SA E+S S ++ + + +E
Sbjct: 476 SSSEEEEEKTSKSAVKK----KPQKVAGGAAPSKPASAKKGKAESSNSSSSDDSSEEEEE 531
Query: 490 SL 491
L
Sbjct: 532 KL 533
Score = 36.2 bits (82), Expect = 0.098
Identities = 90/418 (21%), Positives = 149/418 (35%), Gaps = 90/418 (21%)
Query: 126 GLP--KRADRILSGGALELASQNTDKTSQNQARELPVTENNAQNAKVSRFLKKKQAPVEN 183
GLP K A + + E +S + D+ Q ++ PV + AK ++ KK ++
Sbjct: 113 GLPPGKAAAKASESSSSEESSDDDDEEDQ---KKQPVQKGVKPQAKAAKAPPKKAKSSDS 169
Query: 184 ISPEAPAGKERTLQTPKQKE---PARTFDSPDSDEEEMKVLLGSLMDSSREKNTNQGFSS 240
S + + Q PK A+T P K+ G SS + SS
Sbjct: 170 DSDSSSEDEPPKNQKPKITPVTVKAQTKAPPKPARAAPKIANGKAASSSSSSS-----SS 224
Query: 241 ANVSEEEERKLFSVPSQLRAFTVPSVELSSAKPSQTSHLPTSLAADRTLHSTRSRADYPQ 300
++ + EE K + P + TVP ++ + P + + PT R +
Sbjct: 225 SSSDDSEEEKAAATPKK----TVPKKQVVAKAPVKAATTPT-----------RKSSSSED 269
Query: 301 SHVSSDTASHTPSVSITGAFSN--SVSLKMGHVKLVSSPGRSEAETVDEPVSEGADDSLD 358
S + P + G +S+ S L + P + E +PV E ++DS D
Sbjct: 270 SSSDEEEEQKKPMKNKPGPYSSVPPPSAPPPKKSLGTQPPKKAVEK-QQPV-ESSEDSSD 327
Query: 359 EFRINILSLDGLAPAVSENSDLEQEEESAQRQKTAGKIFRAEASTGQDAPRQAQARSWAS 418
E SD EEE K A S P A+
Sbjct: 328 E------------------SDSSSEEEKKPPTK-------AVVSKATTKPPPAK------ 356
Query: 419 QGKAASAEGDESEVSEHLSASSASAIQQDSTSSMQPPSEAPMVNTVSSAYSEDFENSPSL 478
KAA + D S+ DS+ + PS+ P T +S+ N P++
Sbjct: 357 --KAAESSSDSSD--------------SDSSEDDEAPSK-PAGTTKNSS------NKPAV 393
Query: 479 T----ASEPTAHSKESLDRTLDALSESSSSVKTDLPQTAESRKKSGRHVTRVLVKDTA 532
T A +P A K+ + L+ + S ++ ++ +K+ + V K TA
Sbjct: 394 TTKSPAVKPAAAPKQPVGGGQKLLTRKADSSSSEEESSSSEEEKTKKMVATTKPKATA 451
Score = 31.6 bits (70), Expect = 2.4
Identities = 54/300 (18%), Positives = 107/300 (35%), Gaps = 42/300 (14%)
Query: 239 SSANVSEEEERKLFSVPSQLRAFTVPSVELSSAKPSQTSHLPTSLAADRTLHSTRSRADY 298
S + S EEE ++ P++ +A P++ LP AA + S+ S
Sbjct: 85 SDSEDSSEEEEEVQGPPAK-----------KAAVPAKRVGLPPGKAAAKASESSSSE--- 130
Query: 299 PQSHVSSDTASHTPSVSITGAFSNSVSLKMGHVKLVSSPGRSEAETVDEPVSEGADDSLD 358
+S D G + + K K SS S++ + DEP
Sbjct: 131 -ESSDDDDEEDQKKQPVQKGVKPQAKAAKAPPKKAKSSDSDSDSSSEDEPPKNQK----- 184
Query: 359 EFRINILSLDGLAPAVSENSDLEQEEESAQRQKTAGKIFRAEASTGQDAPRQAQARSWAS 418
P ++ + Q + + + A KI +A++ + + + +
Sbjct: 185 -------------PKITPVTVKAQTKAPPKPARAAPKIANGKAASSSSSSSSSSSSDDSE 231
Query: 419 QGKAASAEGD---------ESEVSEHLSASSASAIQQDSTSSMQPPSEAPMVNTVSSAYS 469
+ KAA+ ++ V + + S+ +DS+S + + PM N S
Sbjct: 232 EEKAAATPKKTVPKKQVVAKAPVKAATTPTRKSSSSEDSSSDEEEEQKKPMKNKPGPYSS 291
Query: 470 EDFENSPSLTASEPTAHSKESLDRTLDALSESSSSVKTDLPQTAESRKKSGRHVTRVLVK 529
++P S T K+++++ S SS ++D E + + V++ K
Sbjct: 292 VPPPSAPPPKKSLGTQPPKKAVEKQQPVESSEDSSDESDSSSEEEKKPPTKAVVSKATTK 351
>gi|4758172 dentin matrix acidic phosphoprotein 1 isoform 1
precursor [Homo sapiens]
Length = 513
Score = 42.0 bits (97), Expect = 0.002
Identities = 49/212 (23%), Positives = 88/212 (41%), Gaps = 25/212 (11%)
Query: 106 NRKLQRNLSDTESDSMTADAGL--PKRADRILSGGALELASQNTDKTSQNQARELPVTEN 163
N ++ SD+ +S + D GL P+R + G + E + +N + ++Q + P +E+
Sbjct: 285 NNTMEEVKSDSTENSNSRDTGLSQPRRDSK---GDSQEDSKENLSQ-EESQNVDGPSSES 340
Query: 164 NAQNAKVSRFLKKKQAPVENISPEAPAGKERTLQTPKQKEPARTFDSPDSDEEEMKVLLG 223
+ Q A +S ++ E +S + T + +E DS S+E+ L
Sbjct: 341 S-QEANLSSQENSSESQEEVVSESRGDNPDPTTSYVEDQE-----DSDSSEEDSSHTLSH 394
Query: 224 SLMDSSREKNTNQGFSSANVSEEEERKLFSVPSQLRAFTVPSVELSSAKPSQTSHLPTSL 283
S +S E+ ++ S N SEE P E SS++ SH ++
Sbjct: 395 SKSESREEQADSESSESLNFSEESPES-------------PEDENSSSQEGLQSHSSSAE 441
Query: 284 AADRTLHSTRSRADYPQSHVSSDTASHTPSVS 315
+ HS +D S S + ++ T S S
Sbjct: 442 SQSEESHSEEDDSDSQDSSRSKEDSNSTESKS 473
Score = 30.0 bits (66), Expect = 7.1
Identities = 35/148 (23%), Positives = 58/148 (39%), Gaps = 10/148 (6%)
Query: 404 GQDAPRQAQARSWASQGKAASAEGDESEVSEHLSASSASAIQQDSTSSMQPPSEAPMVNT 463
G A +S S + A +S S+ L S ++ S SE NT
Sbjct: 228 GNSRMNSAGMKSKESGENSEQANTQDSGGSQLLEHPSRKIFRKSRISEEDDRSELDDNNT 287
Query: 464 VSSAYSEDFENSPSLTA--SEPTAHSK-ESLDRTLDALSESSSSVKTDLPQTAESR---- 516
+ S+ ENS S S+P SK +S + + + LS+ S D P + S+
Sbjct: 288 MEEVKSDSTENSNSRDTGLSQPRRDSKGDSQEDSKENLSQEESQ-NVDGPSSESSQEANL 346
Query: 517 --KKSGRHVTRVLVKDTAVQTPDPAFTY 542
+++ +V ++ PDP +Y
Sbjct: 347 SSQENSSESQEEVVSESRGDNPDPTTSY 374
>gi|121256621 dentin matrix acidic phosphoprotein 1 isoform 2
precursor [Homo sapiens]
Length = 497
Score = 42.0 bits (97), Expect = 0.002
Identities = 49/212 (23%), Positives = 88/212 (41%), Gaps = 25/212 (11%)
Query: 106 NRKLQRNLSDTESDSMTADAGL--PKRADRILSGGALELASQNTDKTSQNQARELPVTEN 163
N ++ SD+ +S + D GL P+R + G + E + +N + ++Q + P +E+
Sbjct: 269 NNTMEEVKSDSTENSNSRDTGLSQPRRDSK---GDSQEDSKENLSQ-EESQNVDGPSSES 324
Query: 164 NAQNAKVSRFLKKKQAPVENISPEAPAGKERTLQTPKQKEPARTFDSPDSDEEEMKVLLG 223
+ Q A +S ++ E +S + T + +E DS S+E+ L
Sbjct: 325 S-QEANLSSQENSSESQEEVVSESRGDNPDPTTSYVEDQE-----DSDSSEEDSSHTLSH 378
Query: 224 SLMDSSREKNTNQGFSSANVSEEEERKLFSVPSQLRAFTVPSVELSSAKPSQTSHLPTSL 283
S +S E+ ++ S N SEE P E SS++ SH ++
Sbjct: 379 SKSESREEQADSESSESLNFSEESPES-------------PEDENSSSQEGLQSHSSSAE 425
Query: 284 AADRTLHSTRSRADYPQSHVSSDTASHTPSVS 315
+ HS +D S S + ++ T S S
Sbjct: 426 SQSEESHSEEDDSDSQDSSRSKEDSNSTESKS 457
Score = 30.0 bits (66), Expect = 7.1
Identities = 35/148 (23%), Positives = 58/148 (39%), Gaps = 10/148 (6%)
Query: 404 GQDAPRQAQARSWASQGKAASAEGDESEVSEHLSASSASAIQQDSTSSMQPPSEAPMVNT 463
G A +S S + A +S S+ L S ++ S SE NT
Sbjct: 212 GNSRMNSAGMKSKESGENSEQANTQDSGGSQLLEHPSRKIFRKSRISEEDDRSELDDNNT 271
Query: 464 VSSAYSEDFENSPSLTA--SEPTAHSK-ESLDRTLDALSESSSSVKTDLPQTAESR---- 516
+ S+ ENS S S+P SK +S + + + LS+ S D P + S+
Sbjct: 272 MEEVKSDSTENSNSRDTGLSQPRRDSKGDSQEDSKENLSQEESQ-NVDGPSSESSQEANL 330
Query: 517 --KKSGRHVTRVLVKDTAVQTPDPAFTY 542
+++ +V ++ PDP +Y
Sbjct: 331 SSQENSSESQEEVVSESRGDNPDPTTSY 358
>gi|239754269 PREDICTED: hypothetical protein [Homo sapiens]
Length = 1531
Score = 42.0 bits (97), Expect = 0.002
Identities = 59/272 (21%), Positives = 98/272 (36%), Gaps = 9/272 (3%)
Query: 270 SAKPSQTSHLPTSLAADRTLHSTRSRADYPQSHVSSDTA-----SHTPSVSITGAFSNSV 324
S S+T+ + T+ ++RT+ ST S S+T S T +VSITG+ + V
Sbjct: 647 STTDSETTMVSTT-GSERTITSTEGSETTTVSATGSETTVSTEGSGTTTVSITGSETTKV 705
Query: 325 SLKMGHVKLVSSPGRSEAETVDEPVSEGADDSLDEFRINILSLDGLAPAVSENSDLEQEE 384
S S+ G SE T SE S + S +G + + E
Sbjct: 706 STTGSETTTTSTEG-SEITTASITGSETTTASTEGSETTTASTEGSETTSASTTGSETTT 764
Query: 385 ES-AQRQKTAGKIFRAEASTGQDAPRQAQARSWASQGKAASAEGDESEVSEHLSASSASA 443
S + T I +E + + S AS K + + SE + + +S +
Sbjct: 765 ASTTSSETTMASIMGSETTMASTIGSETTKVSTAS-SKMTTVFTENSETTIASTTASETT 823
Query: 444 IQQDSTSSMQPPSEAPMVNTVSSAYSEDFENSPSLTASEPTAHSKESLDRTLDALSESSS 503
+ S P S A T +++ + S SE T S ES + T S +
Sbjct: 824 TVSTAGSETIPASTAGSETTTTTSTEGSETTTASTEGSETTTASTESSETTTATTIGSET 883
Query: 504 SVKTDLPQTAESRKKSGRHVTRVLVKDTAVQT 535
+ + + G T + + + T
Sbjct: 884 TTASTEGSETTTTSTEGSETTTASTEGSEITT 915
Score = 35.8 bits (81), Expect = 0.13
Identities = 83/385 (21%), Positives = 139/385 (36%), Gaps = 69/385 (17%)
Query: 207 TFDSPDSDEEEMKVLLGSLMDSSREKNTNQGFSSANVSEEEERKLFSVPSQ-LRAFTVPS 265
T S E M +GS +++ + + + E +F+ S+ +RA TV S
Sbjct: 284 TAASTTGSEPTMASTMGS--ETTMASTIGPETTKVSTASSEVTTVFAAGSETIRASTVGS 341
Query: 266 ----VELSSAKPSQTSHLPTSLAADRTLHS--TRSRADYPQSHVSSDTASHTPSVSITGA 319
V + ++ + S + + + D T S T + + ++ +S S +VS TG+
Sbjct: 342 ETTTVSTTGSETTTASIMGSETSTDSTTGSETTTASTEGSETTTASTEGSEATTVSTTGS 401
Query: 320 FSNSVSLKMGHVKLVSSPGRSEAETVDEPVSEGADDSLDEFRINILSLDGLAPAVSENSD 379
+ +VS+ + G SE V V E S + I I S SE +
Sbjct: 402 ETTTVSITDSETTTTCTEG-SEMTAVSTTVFETTTASTEGSEITIASTSD-----SETTT 455
Query: 380 LEQEEESAQRQKTAGKIFRAEASTGQDAPRQAQ-----------------ARSWASQGKA 422
E TAG + +TG + + A + S+ A
Sbjct: 456 ASTEGSETTTVTTAGSETKTAYTTGSETTTASNTGLETTTVFTIGSDTTTASTEGSETTA 515
Query: 423 ASAEGDE-----SEVSEHLSASSA-------SAIQQDSTSSMQPPSEAPMVNTV------ 464
SA G E +E SE+ + S+ S ++T++ SE V+T
Sbjct: 516 VSATGSEMTTVSTEGSENTTVSTTGSETTTVSTTGLETTTTSTEGSEMTTVSTTGAETTT 575
Query: 465 -----------SSAYSE-------DFENSPSLTASEPTAHSKESLDRTLDALSESSSSVK 506
S+A SE D EN+ + TA T + + T A S +SS
Sbjct: 576 DSTEGSGTTAASTAGSETTTVSTADSENTTASTADSETTSASTTGSETTTA-STTSSETT 634
Query: 507 TDLPQTAESRKKSGRHVTRVLVKDT 531
T + +E+ S +V T
Sbjct: 635 TASTEGSETTTVSTTDSETTMVSTT 659
Score = 34.3 bits (77), Expect = 0.37
Identities = 49/260 (18%), Positives = 88/260 (33%), Gaps = 11/260 (4%)
Query: 262 TVPSVELSSAKPSQTSHLPTSLAADRTLHSTRSRADYPQSHVSSDTASHTPSVSITGAFS 321
TV S+ + T+ T+ + +T + ++ S T S T VSI+G+
Sbjct: 6 TVAPAAGSNTTTASTTGSETTTILIKASETTTASTAGSETTTPSPTGSQTTIVSISGSEI 65
Query: 322 NSVSLKMGHVKLVSSPG--------RSEAETVDEPVSEGADDSLDEFRINILSLDGLAPA 373
+ S VSS G TV SE S+ ++S G
Sbjct: 66 TTTSTAGSENTTVSSAGSGTTTASMAGSETTVSTAGSETTTVSITGTETTMVSAMGSETT 125
Query: 374 VSENSDLEQEEES-AQRQKTAGKIFRAEASTGQDAPRQAQARSWASQGKAASAEGDESEV 432
+ + E S A + T +E +T A + A S +
Sbjct: 126 TNSTTSSETTVTSTAGSETTTVSTVGSETTTAYTADSETTAASTTGSEMTTVFTAGSETI 185
Query: 433 SEHLSASSASAIQQDSTSSMQPPSEAPMVNTVSSAYSEDFENSPSLTASEPTAHSKESLD 492
+ + S + + + + + T S+A+SE + S SE T S +
Sbjct: 186 TPSTAGSETTTVSTAGSETTTVSTTGSETTTASTAHSE--TTAASTMGSETTKVSTAGSE 243
Query: 493 RTLDALSESSSSVKTDLPQT 512
T+ +++ T+ +T
Sbjct: 244 TTVSTAGSETTAASTEDSET 263
>gi|169168665 PREDICTED: hypothetical protein [Homo sapiens]
Length = 1521
Score = 42.0 bits (97), Expect = 0.002
Identities = 59/272 (21%), Positives = 98/272 (36%), Gaps = 9/272 (3%)
Query: 270 SAKPSQTSHLPTSLAADRTLHSTRSRADYPQSHVSSDTA-----SHTPSVSITGAFSNSV 324
S S+T+ + T+ ++RT+ ST S S+T S T +VSITG+ + V
Sbjct: 647 STTDSETTMVSTT-GSERTITSTEGSETTTVSATGSETTVSTEGSGTTTVSITGSETTKV 705
Query: 325 SLKMGHVKLVSSPGRSEAETVDEPVSEGADDSLDEFRINILSLDGLAPAVSENSDLEQEE 384
S S+ G SE T SE S + S +G + + E
Sbjct: 706 STTGSETTTTSTEG-SEITTASITGSETTTASTEGSETTTASTEGSETTSASTTGSETTT 764
Query: 385 ES-AQRQKTAGKIFRAEASTGQDAPRQAQARSWASQGKAASAEGDESEVSEHLSASSASA 443
S + T I +E + + S AS K + + SE + + +S +
Sbjct: 765 ASTTSSETTMASIMGSETTMASTIGSETTKVSTAS-SKMTTVFTENSETTIASTTASETT 823
Query: 444 IQQDSTSSMQPPSEAPMVNTVSSAYSEDFENSPSLTASEPTAHSKESLDRTLDALSESSS 503
+ S P S A T +++ + S SE T S ES + T S +
Sbjct: 824 TVSTAGSETIPASTAGSETTTTTSTEGSETTTASTEGSETTTASTESSETTTATTIGSET 883
Query: 504 SVKTDLPQTAESRKKSGRHVTRVLVKDTAVQT 535
+ + + G T + + + T
Sbjct: 884 TTASTEGSETTTTSTEGSETTTASTEGSEITT 915
Score = 35.8 bits (81), Expect = 0.13
Identities = 83/385 (21%), Positives = 139/385 (36%), Gaps = 69/385 (17%)
Query: 207 TFDSPDSDEEEMKVLLGSLMDSSREKNTNQGFSSANVSEEEERKLFSVPSQ-LRAFTVPS 265
T S E M +GS +++ + + + E +F+ S+ +RA TV S
Sbjct: 284 TAASTTGSEPTMASTMGS--ETTMASTIGPETTKVSTASSEVTTVFAAGSETIRASTVGS 341
Query: 266 ----VELSSAKPSQTSHLPTSLAADRTLHS--TRSRADYPQSHVSSDTASHTPSVSITGA 319
V + ++ + S + + + D T S T + + ++ +S S +VS TG+
Sbjct: 342 ETTTVSTTGSETTTASIMGSETSTDSTTGSETTTASTEGSETTTASTEGSEATTVSTTGS 401
Query: 320 FSNSVSLKMGHVKLVSSPGRSEAETVDEPVSEGADDSLDEFRINILSLDGLAPAVSENSD 379
+ +VS+ + G SE V V E S + I I S SE +
Sbjct: 402 ETTTVSITDSETTTTCTEG-SEMTAVSTTVFETTTASTEGSEITIASTSD-----SETTT 455
Query: 380 LEQEEESAQRQKTAGKIFRAEASTGQDAPRQAQ-----------------ARSWASQGKA 422
E TAG + +TG + + A + S+ A
Sbjct: 456 ASTEGSETTTVTTAGSETKTAYTTGSETTTASNTGLETTTVFTIGSDTTTASTEGSETTA 515
Query: 423 ASAEGDE-----SEVSEHLSASSA-------SAIQQDSTSSMQPPSEAPMVNTV------ 464
SA G E +E SE+ + S+ S ++T++ SE V+T
Sbjct: 516 VSATGSEMTTVSTEGSENTTVSTTGSETTTVSTTGLETTTTSTEGSEMTTVSTTGAETTT 575
Query: 465 -----------SSAYSE-------DFENSPSLTASEPTAHSKESLDRTLDALSESSSSVK 506
S+A SE D EN+ + TA T + + T A S +SS
Sbjct: 576 DSTEGSGTTAASTAGSETTTVSTADSENTTASTADSETTSASTTGSETTTA-STTSSETT 634
Query: 507 TDLPQTAESRKKSGRHVTRVLVKDT 531
T + +E+ S +V T
Sbjct: 635 TASTEGSETTTVSTTDSETTMVSTT 659
Score = 34.3 bits (77), Expect = 0.37
Identities = 49/260 (18%), Positives = 88/260 (33%), Gaps = 11/260 (4%)
Query: 262 TVPSVELSSAKPSQTSHLPTSLAADRTLHSTRSRADYPQSHVSSDTASHTPSVSITGAFS 321
TV S+ + T+ T+ + +T + ++ S T S T VSI+G+
Sbjct: 6 TVAPAAGSNTTTASTTGSETTTILIKASETTTASTAGSETTTPSPTGSQTTIVSISGSEI 65
Query: 322 NSVSLKMGHVKLVSSPG--------RSEAETVDEPVSEGADDSLDEFRINILSLDGLAPA 373
+ S VSS G TV SE S+ ++S G
Sbjct: 66 TTTSTAGSENTTVSSAGSGTTTASMAGSETTVSTAGSETTTVSITGTETTMVSAMGSETT 125
Query: 374 VSENSDLEQEEES-AQRQKTAGKIFRAEASTGQDAPRQAQARSWASQGKAASAEGDESEV 432
+ + E S A + T +E +T A + A S +
Sbjct: 126 TNSTTSSETTVTSTAGSETTTVSTVGSETTTAYTADSETTAASTTGSEMTTVFTAGSETI 185
Query: 433 SEHLSASSASAIQQDSTSSMQPPSEAPMVNTVSSAYSEDFENSPSLTASEPTAHSKESLD 492
+ + S + + + + + T S+A+SE + S SE T S +
Sbjct: 186 TPSTAGSETTTVSTAGSETTTVSTTGSETTTASTAHSE--TTAASTMGSETTKVSTAGSE 243
Query: 493 RTLDALSESSSSVKTDLPQT 512
T+ +++ T+ +T
Sbjct: 244 TTVSTAGSETTAASTEDSET 263
>gi|113417486 PREDICTED: hypothetical protein [Homo sapiens]
Length = 1612
Score = 42.0 bits (97), Expect = 0.002
Identities = 59/272 (21%), Positives = 98/272 (36%), Gaps = 9/272 (3%)
Query: 270 SAKPSQTSHLPTSLAADRTLHSTRSRADYPQSHVSSDTA-----SHTPSVSITGAFSNSV 324
S S+T+ + T+ ++RT+ ST S S+T S T +VSITG+ + V
Sbjct: 647 STTDSETTMVSTT-GSERTITSTEGSETTTVSATGSETTVSTEGSGTTTVSITGSETTKV 705
Query: 325 SLKMGHVKLVSSPGRSEAETVDEPVSEGADDSLDEFRINILSLDGLAPAVSENSDLEQEE 384
S S+ G SE T SE S + S +G + + E
Sbjct: 706 STTGSETTTTSTEG-SEITTASITGSETTTASTEGSETTTASTEGSETTSASTTGSETTT 764
Query: 385 ES-AQRQKTAGKIFRAEASTGQDAPRQAQARSWASQGKAASAEGDESEVSEHLSASSASA 443
S + T I +E + + S AS K + + SE + + +S +
Sbjct: 765 ASTTSSETTMASIMGSETTMASTIGSETTKVSTAS-SKMTTVFTENSETTIASTTASETT 823
Query: 444 IQQDSTSSMQPPSEAPMVNTVSSAYSEDFENSPSLTASEPTAHSKESLDRTLDALSESSS 503
+ S P S A T +++ + S SE T S ES + T S +
Sbjct: 824 TVSTAGSETIPASTAGSETTTTTSTEGSETTTASTEGSETTTASTESSETTTATTIGSET 883
Query: 504 SVKTDLPQTAESRKKSGRHVTRVLVKDTAVQT 535
+ + + G T + + + T
Sbjct: 884 TTASTEGSETTTTSTEGSETTTASTEGSEITT 915
Score = 35.8 bits (81), Expect = 0.13
Identities = 83/385 (21%), Positives = 139/385 (36%), Gaps = 69/385 (17%)
Query: 207 TFDSPDSDEEEMKVLLGSLMDSSREKNTNQGFSSANVSEEEERKLFSVPSQ-LRAFTVPS 265
T S E M +GS +++ + + + E +F+ S+ +RA TV S
Sbjct: 284 TAASTTGSEPTMASTMGS--ETTMASTIGPETTKVSTASSEVTTVFAAGSETIRASTVGS 341
Query: 266 ----VELSSAKPSQTSHLPTSLAADRTLHS--TRSRADYPQSHVSSDTASHTPSVSITGA 319
V + ++ + S + + + D T S T + + ++ +S S +VS TG+
Sbjct: 342 ETTTVSTTGSETTTASIMGSETSTDSTTGSETTTASTEGSETTTASTEGSEATTVSTTGS 401
Query: 320 FSNSVSLKMGHVKLVSSPGRSEAETVDEPVSEGADDSLDEFRINILSLDGLAPAVSENSD 379
+ +VS+ + G SE V V E S + I I S SE +
Sbjct: 402 ETTTVSITDSETTTTCTEG-SEMTAVSTTVFETTTASTEGSEITIASTSD-----SETTT 455
Query: 380 LEQEEESAQRQKTAGKIFRAEASTGQDAPRQAQ-----------------ARSWASQGKA 422
E TAG + +TG + + A + S+ A
Sbjct: 456 ASTEGSETTTVTTAGSETKTAYTTGSETTTASNTGLETTTVFTIGSDTTTASTEGSETTA 515
Query: 423 ASAEGDE-----SEVSEHLSASSA-------SAIQQDSTSSMQPPSEAPMVNTV------ 464
SA G E +E SE+ + S+ S ++T++ SE V+T
Sbjct: 516 VSATGSEMTTVSTEGSENTTVSTTGSETTTVSTTGLETTTTSTEGSEMTTVSTTGAETTT 575
Query: 465 -----------SSAYSE-------DFENSPSLTASEPTAHSKESLDRTLDALSESSSSVK 506
S+A SE D EN+ + TA T + + T A S +SS
Sbjct: 576 DSTEGSGTTAASTAGSETTTVSTADSENTTASTADSETTSASTTGSETTTA-STTSSETT 634
Query: 507 TDLPQTAESRKKSGRHVTRVLVKDT 531
T + +E+ S +V T
Sbjct: 635 TASTEGSETTTVSTTDSETTMVSTT 659
Score = 34.3 bits (77), Expect = 0.37
Identities = 49/260 (18%), Positives = 88/260 (33%), Gaps = 11/260 (4%)
Query: 262 TVPSVELSSAKPSQTSHLPTSLAADRTLHSTRSRADYPQSHVSSDTASHTPSVSITGAFS 321
TV S+ + T+ T+ + +T + ++ S T S T VSI+G+
Sbjct: 6 TVAPAAGSNTTTASTTGSETTTILIKASETTTASTAGSETTTPSPTGSQTTIVSISGSEI 65
Query: 322 NSVSLKMGHVKLVSSPG--------RSEAETVDEPVSEGADDSLDEFRINILSLDGLAPA 373
+ S VSS G TV SE S+ ++S G
Sbjct: 66 TTTSTAGSENTTVSSAGSGTTTASMAGSETTVSTAGSETTTVSITGTETTMVSAMGSETT 125
Query: 374 VSENSDLEQEEES-AQRQKTAGKIFRAEASTGQDAPRQAQARSWASQGKAASAEGDESEV 432
+ + E S A + T +E +T A + A S +
Sbjct: 126 TNSTTSSETTVTSTAGSETTTVSTVGSETTTAYTADSETTAASTTGSEMTTVFTAGSETI 185
Query: 433 SEHLSASSASAIQQDSTSSMQPPSEAPMVNTVSSAYSEDFENSPSLTASEPTAHSKESLD 492
+ + S + + + + + T S+A+SE + S SE T S +
Sbjct: 186 TPSTAGSETTTVSTAGSETTTVSTTGSETTTASTAHSE--TTAASTMGSETTKVSTAGSE 243
Query: 493 RTLDALSESSSSVKTDLPQT 512
T+ +++ T+ +T
Sbjct: 244 TTVSTAGSETTAASTEDSET 263
>gi|239740898 PREDICTED: hypothetical protein [Homo sapiens]
Length = 1542
Score = 42.0 bits (97), Expect = 0.002
Identities = 59/272 (21%), Positives = 98/272 (36%), Gaps = 9/272 (3%)
Query: 270 SAKPSQTSHLPTSLAADRTLHSTRSRADYPQSHVSSDTA-----SHTPSVSITGAFSNSV 324
S S+T+ + T+ ++RT+ ST S S+T S T +VSITG+ + V
Sbjct: 668 STTDSETTMVSTT-GSERTITSTEGSETTTVSATGSETTVSTEGSGTTTVSITGSETTKV 726
Query: 325 SLKMGHVKLVSSPGRSEAETVDEPVSEGADDSLDEFRINILSLDGLAPAVSENSDLEQEE 384
S S+ G SE T SE S + S +G + + E
Sbjct: 727 STTGSETTTTSTEG-SEITTASITGSETTTASTEGSETTTASTEGSETTSASTTGSETTT 785
Query: 385 ES-AQRQKTAGKIFRAEASTGQDAPRQAQARSWASQGKAASAEGDESEVSEHLSASSASA 443
S + T I +E + + S AS K + + SE + + +S +
Sbjct: 786 ASTTSSETTMASIMGSETTMASTIGSETTKVSTAS-SKMTTVFTENSETTIASTTASETT 844
Query: 444 IQQDSTSSMQPPSEAPMVNTVSSAYSEDFENSPSLTASEPTAHSKESLDRTLDALSESSS 503
+ S P S A T +++ + S SE T S ES + T S +
Sbjct: 845 TVSTAGSETIPASTAGSETTTTTSTEGSETTTASTEGSETTTASTESSETTTATTIGSET 904
Query: 504 SVKTDLPQTAESRKKSGRHVTRVLVKDTAVQT 535
+ + + G T + + + T
Sbjct: 905 TTASTEGSETTTTSTEGSETTTASTEGSEITT 936
Score = 38.9 bits (89), Expect = 0.015
Identities = 52/283 (18%), Positives = 96/283 (33%), Gaps = 11/283 (3%)
Query: 239 SSANVSEEEERKLFSVPSQLRAFTVPSVELSSAKPSQTSHLPTSLAADRTLHSTRSRADY 298
S A + + K+ + S TV S+ + T+ T+ + +T +
Sbjct: 4 SEATTTSTADSKVITASSMSSETTVAPAAGSNTTTASTTGSETTTILIKASETTTASTAG 63
Query: 299 PQSHVSSDTASHTPSVSITGAFSNSVSLKMGHVKLVSSPG--------RSEAETVDEPVS 350
++ S T S T VSI+G+ + S VSS G T+ S
Sbjct: 64 SETTTPSPTGSQTTIVSISGSEITTTSTAGSENTTVSSAGSGTTTASMAGSESTISTAGS 123
Query: 351 EGADDSLDEFRINILSLDGLAPAVSENSDLEQEEES-AQRQKTAGKIFRAEASTGQDAPR 409
E S+ ++S G + + E S A + T +E +T A
Sbjct: 124 ETTTVSITGTETTMVSAMGSETTTNSTTSSETTVTSTAGSETTTVSTVGSETTTAYTADS 183
Query: 410 QAQARSWASQGKAASAEGDESEVSEHLSASSASAIQQDSTSSMQPPSEAPMVNTVSSAYS 469
+ A S ++ + S + + + + + T S+A+S
Sbjct: 184 ETTAASTTGSEMTTVFTAGSETITPSTAGSETTTVSTAGSETTTVSTTGSETTTASTAHS 243
Query: 470 EDFENSPSLTASEPTAHSKESLDRTLDALSESSSSVKTDLPQT 512
E + S SE T S + T+ +++ T+ +T
Sbjct: 244 E--TTAASTMGSETTKVSTAGSETTVSTAGSETTAASTEDSET 284
Score = 35.8 bits (81), Expect = 0.13
Identities = 83/385 (21%), Positives = 139/385 (36%), Gaps = 69/385 (17%)
Query: 207 TFDSPDSDEEEMKVLLGSLMDSSREKNTNQGFSSANVSEEEERKLFSVPSQ-LRAFTVPS 265
T S E M +GS +++ + + + E +F+ S+ +RA TV S
Sbjct: 305 TAASTTGSEPTMASTMGS--ETTMASTIGPETTKVSTASSEVTTVFAAGSETIRASTVGS 362
Query: 266 ----VELSSAKPSQTSHLPTSLAADRTLHS--TRSRADYPQSHVSSDTASHTPSVSITGA 319
V + ++ + S + + + D T S T + + ++ +S S +VS TG+
Sbjct: 363 ETTTVSTTGSETTTASIMGSETSTDSTTGSETTTASTEGSETTTASTEGSEATTVSTTGS 422
Query: 320 FSNSVSLKMGHVKLVSSPGRSEAETVDEPVSEGADDSLDEFRINILSLDGLAPAVSENSD 379
+ +VS+ + G SE V V E S + I I S SE +
Sbjct: 423 ETTTVSITDSETTTTCTEG-SEMTAVSTTVFETTTASTEGSEITIASTSD-----SETTT 476
Query: 380 LEQEEESAQRQKTAGKIFRAEASTGQDAPRQAQ-----------------ARSWASQGKA 422
E TAG + +TG + + A + S+ A
Sbjct: 477 ASTEGSETTTVTTAGSETKTAYTTGSETTTASNTGLETTTVFTIGSDTTTASTEGSETTA 536
Query: 423 ASAEGDE-----SEVSEHLSASSA-------SAIQQDSTSSMQPPSEAPMVNTV------ 464
SA G E +E SE+ + S+ S ++T++ SE V+T
Sbjct: 537 VSATGSEMTTVSTEGSENTTVSTTGSETTTVSTTGLETTTTSTEGSEMTTVSTTGAETTT 596
Query: 465 -----------SSAYSE-------DFENSPSLTASEPTAHSKESLDRTLDALSESSSSVK 506
S+A SE D EN+ + TA T + + T A S +SS
Sbjct: 597 DSTEGSGTTAASTAGSETTTVSTADSENTTASTADSETTSASTTGSETTTA-STTSSETT 655
Query: 507 TDLPQTAESRKKSGRHVTRVLVKDT 531
T + +E+ S +V T
Sbjct: 656 TASTEGSETTTVSTTDSETTMVSTT 680
>gi|239740777 PREDICTED: hypothetical protein [Homo sapiens]
Length = 1612
Score = 42.0 bits (97), Expect = 0.002
Identities = 59/272 (21%), Positives = 98/272 (36%), Gaps = 9/272 (3%)
Query: 270 SAKPSQTSHLPTSLAADRTLHSTRSRADYPQSHVSSDTA-----SHTPSVSITGAFSNSV 324
S S+T+ + T+ ++RT+ ST S S+T S T +VSITG+ + V
Sbjct: 647 STTDSETTMVSTT-GSERTITSTEGSETTTVSATGSETTVSTEGSGTTTVSITGSETTKV 705
Query: 325 SLKMGHVKLVSSPGRSEAETVDEPVSEGADDSLDEFRINILSLDGLAPAVSENSDLEQEE 384
S S+ G SE T SE S + S +G + + E
Sbjct: 706 STTGSETTTTSTEG-SEITTASITGSETTTASTEGSETTTASTEGSETTSASTTGSETTT 764
Query: 385 ES-AQRQKTAGKIFRAEASTGQDAPRQAQARSWASQGKAASAEGDESEVSEHLSASSASA 443
S + T I +E + + S AS K + + SE + + +S +
Sbjct: 765 ASTTSSETTMASIMGSETTMASTIGSETTKVSTAS-SKMTTVFTENSETTIASTTASETT 823
Query: 444 IQQDSTSSMQPPSEAPMVNTVSSAYSEDFENSPSLTASEPTAHSKESLDRTLDALSESSS 503
+ S P S A T +++ + S SE T S ES + T S +
Sbjct: 824 TVSTAGSETIPASTAGSETTTTTSTEGSETTTASTEGSETTTASTESSETTTATTIGSET 883
Query: 504 SVKTDLPQTAESRKKSGRHVTRVLVKDTAVQT 535
+ + + G T + + + T
Sbjct: 884 TTASTEGSETTTTSTEGSETTTASTEGSEITT 915
Score = 35.8 bits (81), Expect = 0.13
Identities = 83/385 (21%), Positives = 139/385 (36%), Gaps = 69/385 (17%)
Query: 207 TFDSPDSDEEEMKVLLGSLMDSSREKNTNQGFSSANVSEEEERKLFSVPSQ-LRAFTVPS 265
T S E M +GS +++ + + + E +F+ S+ +RA TV S
Sbjct: 284 TAASTTGSEPTMASTMGS--ETTMASTIGPETTKVSTASSEVTTVFAAGSETIRASTVGS 341
Query: 266 ----VELSSAKPSQTSHLPTSLAADRTLHS--TRSRADYPQSHVSSDTASHTPSVSITGA 319
V + ++ + S + + + D T S T + + ++ +S S +VS TG+
Sbjct: 342 ETTTVSTTGSETTTASIMGSETSTDSTTGSETTTASTEGSETTTASTEGSEATTVSTTGS 401
Query: 320 FSNSVSLKMGHVKLVSSPGRSEAETVDEPVSEGADDSLDEFRINILSLDGLAPAVSENSD 379
+ +VS+ + G SE V V E S + I I S SE +
Sbjct: 402 ETTTVSITDSETTTTCTEG-SEMTAVSTTVFETTTASTEGSEITIASTSD-----SETTT 455
Query: 380 LEQEEESAQRQKTAGKIFRAEASTGQDAPRQAQ-----------------ARSWASQGKA 422
E TAG + +TG + + A + S+ A
Sbjct: 456 ASTEGSETTTVTTAGSETKTAYTTGSETTTASNTGLETTTVFTIGSDTTTASTEGSETTA 515
Query: 423 ASAEGDE-----SEVSEHLSASSA-------SAIQQDSTSSMQPPSEAPMVNTV------ 464
SA G E +E SE+ + S+ S ++T++ SE V+T
Sbjct: 516 VSATGSEMTTVSTEGSENTTVSTTGSETTTVSTTGLETTTTSTEGSEMTTVSTTGAETTT 575
Query: 465 -----------SSAYSE-------DFENSPSLTASEPTAHSKESLDRTLDALSESSSSVK 506
S+A SE D EN+ + TA T + + T A S +SS
Sbjct: 576 DSTEGSGTTAASTAGSETTTVSTADSENTTASTADSETTSASTTGSETTTA-STTSSETT 634
Query: 507 TDLPQTAESRKKSGRHVTRVLVKDT 531
T + +E+ S +V T
Sbjct: 635 TASTEGSETTTVSTTDSETTMVSTT 659
Score = 34.3 bits (77), Expect = 0.37
Identities = 49/260 (18%), Positives = 88/260 (33%), Gaps = 11/260 (4%)
Query: 262 TVPSVELSSAKPSQTSHLPTSLAADRTLHSTRSRADYPQSHVSSDTASHTPSVSITGAFS 321
TV S+ + T+ T+ + +T + ++ S T S T VSI+G+
Sbjct: 6 TVAPAAGSNTTTASTTGSETTTILIKASETTTASTAGSETTTPSPTGSQTTIVSISGSEI 65
Query: 322 NSVSLKMGHVKLVSSPG--------RSEAETVDEPVSEGADDSLDEFRINILSLDGLAPA 373
+ S VSS G TV SE S+ ++S G
Sbjct: 66 TTTSTAGSENTTVSSAGSGTTTASMAGSETTVSTAGSETTTVSITGTETTMVSAMGSETT 125
Query: 374 VSENSDLEQEEES-AQRQKTAGKIFRAEASTGQDAPRQAQARSWASQGKAASAEGDESEV 432
+ + E S A + T +E +T A + A S +
Sbjct: 126 TNSTTSSETTVTSTAGSETTTVSTVGSETTTAYTADSETTAASTTGSEMTTVFTAGSETI 185
Query: 433 SEHLSASSASAIQQDSTSSMQPPSEAPMVNTVSSAYSEDFENSPSLTASEPTAHSKESLD 492
+ + S + + + + + T S+A+SE + S SE T S +
Sbjct: 186 TPSTAGSETTTVSTAGSETTTVSTTGSETTTASTAHSE--TTAASTMGSETTKVSTAGSE 243
Query: 493 RTLDALSESSSSVKTDLPQT 512
T+ +++ T+ +T
Sbjct: 244 TTVSTAGSETTAASTEDSET 263
>gi|239740724 PREDICTED: hypothetical protein [Homo sapiens]
Length = 1704
Score = 42.0 bits (97), Expect = 0.002
Identities = 59/272 (21%), Positives = 98/272 (36%), Gaps = 9/272 (3%)
Query: 270 SAKPSQTSHLPTSLAADRTLHSTRSRADYPQSHVSSDTA-----SHTPSVSITGAFSNSV 324
S S+T+ + T+ ++RT+ ST S S+T S T +VSITG+ + V
Sbjct: 647 STTDSETTMVSTT-GSERTITSTEGSETTTVSATGSETTVSTEGSGTTTVSITGSETTKV 705
Query: 325 SLKMGHVKLVSSPGRSEAETVDEPVSEGADDSLDEFRINILSLDGLAPAVSENSDLEQEE 384
S S+ G SE T SE S + S +G + + E
Sbjct: 706 STTGSETTTTSTEG-SEITTASITGSETTTASTEGSETTTASTEGSETTSASTTGSETTT 764
Query: 385 ES-AQRQKTAGKIFRAEASTGQDAPRQAQARSWASQGKAASAEGDESEVSEHLSASSASA 443
S + T I +E + + S AS K + + SE + + +S +
Sbjct: 765 ASTTSSETTMASIMGSETTMASTIGSETTKVSTAS-SKMTTVFTENSETTIASTTASETT 823
Query: 444 IQQDSTSSMQPPSEAPMVNTVSSAYSEDFENSPSLTASEPTAHSKESLDRTLDALSESSS 503
+ S P S A T +++ + S SE T S ES + T S +
Sbjct: 824 TVSTAGSETIPASTAGSETTTTTSTEGSETTTASTEGSETTTASTESSETTTATTIGSET 883
Query: 504 SVKTDLPQTAESRKKSGRHVTRVLVKDTAVQT 535
+ + + G T + + + T
Sbjct: 884 TTASTEGSETTTTSTEGSETTTASTEGSEITT 915
Score = 35.8 bits (81), Expect = 0.13
Identities = 83/385 (21%), Positives = 139/385 (36%), Gaps = 69/385 (17%)
Query: 207 TFDSPDSDEEEMKVLLGSLMDSSREKNTNQGFSSANVSEEEERKLFSVPSQ-LRAFTVPS 265
T S E M +GS +++ + + + E +F+ S+ +RA TV S
Sbjct: 284 TAASTTGSEPTMASTMGS--ETTMASTIGPETTKVSTASSEVTTVFAAGSETIRASTVGS 341
Query: 266 ----VELSSAKPSQTSHLPTSLAADRTLHS--TRSRADYPQSHVSSDTASHTPSVSITGA 319
V + ++ + S + + + D T S T + + ++ +S S +VS TG+
Sbjct: 342 ETTTVSTTGSETTTASIMGSETSTDSTTGSETTTASTEGSETTTASTEGSEATTVSTTGS 401
Query: 320 FSNSVSLKMGHVKLVSSPGRSEAETVDEPVSEGADDSLDEFRINILSLDGLAPAVSENSD 379
+ +VS+ + G SE V V E S + I I S SE +
Sbjct: 402 ETTTVSITDSETTTTCTEG-SEMTAVSTTVFETTTASTEGSEITIASTSD-----SETTT 455
Query: 380 LEQEEESAQRQKTAGKIFRAEASTGQDAPRQAQ-----------------ARSWASQGKA 422
E TAG + +TG + + A + S+ A
Sbjct: 456 ASTEGSETTTVTTAGSETKTAYTTGSETTTASNTGLETTTVFTIGSDTTTASTEGSETTA 515
Query: 423 ASAEGDE-----SEVSEHLSASSA-------SAIQQDSTSSMQPPSEAPMVNTV------ 464
SA G E +E SE+ + S+ S ++T++ SE V+T
Sbjct: 516 VSATGSEMTTVSTEGSENTTVSTTGSETTTVSTTGLETTTTSTEGSEMTTVSTTGAETTT 575
Query: 465 -----------SSAYSE-------DFENSPSLTASEPTAHSKESLDRTLDALSESSSSVK 506
S+A SE D EN+ + TA T + + T A S +SS
Sbjct: 576 DSTEGSGTTAASTAGSETTTVSTADSENTTASTADSETTSASTTGSETTTA-STTSSETT 634
Query: 507 TDLPQTAESRKKSGRHVTRVLVKDT 531
T + +E+ S +V T
Sbjct: 635 TASTEGSETTTVSTTDSETTMVSTT 659
Score = 34.3 bits (77), Expect = 0.37
Identities = 49/260 (18%), Positives = 88/260 (33%), Gaps = 11/260 (4%)
Query: 262 TVPSVELSSAKPSQTSHLPTSLAADRTLHSTRSRADYPQSHVSSDTASHTPSVSITGAFS 321
TV S+ + T+ T+ + +T + ++ S T S T VSI+G+
Sbjct: 6 TVAPAAGSNTTTASTTGSETTTILIKASETTTASTAGSETTTPSPTGSQTTIVSISGSEI 65
Query: 322 NSVSLKMGHVKLVSSPG--------RSEAETVDEPVSEGADDSLDEFRINILSLDGLAPA 373
+ S VSS G TV SE S+ ++S G
Sbjct: 66 TTTSTAGSENTTVSSAGSGTTTASMAGSETTVSTAGSETTTVSITGTETTMVSAMGSETT 125
Query: 374 VSENSDLEQEEES-AQRQKTAGKIFRAEASTGQDAPRQAQARSWASQGKAASAEGDESEV 432
+ + E S A + T +E +T A + A S +
Sbjct: 126 TNSTTSSETTVTSTAGSETTTVSTVGSETTTAYTADSETTAASTTGSEMTTVFTAGSETI 185
Query: 433 SEHLSASSASAIQQDSTSSMQPPSEAPMVNTVSSAYSEDFENSPSLTASEPTAHSKESLD 492
+ + S + + + + + T S+A+SE + S SE T S +
Sbjct: 186 TPSTAGSETTTVSTAGSETTTVSTTGSETTTASTAHSE--TTAASTMGSETTKVSTAGSE 243
Query: 493 RTLDALSESSSSVKTDLPQT 512
T+ +++ T+ +T
Sbjct: 244 TTVSTAGSETTAASTEDSET 263
>gi|239740674 PREDICTED: hypothetical protein [Homo sapiens]
Length = 1531
Score = 42.0 bits (97), Expect = 0.002
Identities = 59/272 (21%), Positives = 98/272 (36%), Gaps = 9/272 (3%)
Query: 270 SAKPSQTSHLPTSLAADRTLHSTRSRADYPQSHVSSDTA-----SHTPSVSITGAFSNSV 324
S S+T+ + T+ ++RT+ ST S S+T S T +VSITG+ + V
Sbjct: 647 STTDSETTMVSTT-GSERTITSTEGSETTTVSATGSETTVSTEGSGTTTVSITGSETTKV 705
Query: 325 SLKMGHVKLVSSPGRSEAETVDEPVSEGADDSLDEFRINILSLDGLAPAVSENSDLEQEE 384
S S+ G SE T SE S + S +G + + E
Sbjct: 706 STTGSETTTTSTEG-SEITTASITGSETTTASTEGSETTTASTEGSETTSASTTGSETTT 764
Query: 385 ES-AQRQKTAGKIFRAEASTGQDAPRQAQARSWASQGKAASAEGDESEVSEHLSASSASA 443
S + T I +E + + S AS K + + SE + + +S +
Sbjct: 765 ASTTSSETTMASIMGSETTMASTIGSETTKVSTAS-SKMTTVFTENSETTIASTTASETT 823
Query: 444 IQQDSTSSMQPPSEAPMVNTVSSAYSEDFENSPSLTASEPTAHSKESLDRTLDALSESSS 503
+ S P S A T +++ + S SE T S ES + T S +
Sbjct: 824 TVSTAGSETIPASTAGSETTTTTSTEGSETTTASTEGSETTTASTESSETTTATTIGSET 883
Query: 504 SVKTDLPQTAESRKKSGRHVTRVLVKDTAVQT 535
+ + + G T + + + T
Sbjct: 884 TTASTEGSETTTTSTEGSETTTASTEGSEITT 915
Score = 35.8 bits (81), Expect = 0.13
Identities = 83/385 (21%), Positives = 139/385 (36%), Gaps = 69/385 (17%)
Query: 207 TFDSPDSDEEEMKVLLGSLMDSSREKNTNQGFSSANVSEEEERKLFSVPSQ-LRAFTVPS 265
T S E M +GS +++ + + + E +F+ S+ +RA TV S
Sbjct: 284 TAASTTGSEPTMASTMGS--ETTMASTIGPETTKVSTASSEVTTVFAAGSETIRASTVGS 341
Query: 266 ----VELSSAKPSQTSHLPTSLAADRTLHS--TRSRADYPQSHVSSDTASHTPSVSITGA 319
V + ++ + S + + + D T S T + + ++ +S S +VS TG+
Sbjct: 342 ETTTVSTTGSETTTASIMGSETSTDSTTGSETTTASTEGSETTTASTEGSEATTVSTTGS 401
Query: 320 FSNSVSLKMGHVKLVSSPGRSEAETVDEPVSEGADDSLDEFRINILSLDGLAPAVSENSD 379
+ +VS+ + G SE V V E S + I I S SE +
Sbjct: 402 ETTTVSITDSETTTTCTEG-SEMTAVSTTVFETTTASTEGSEITIASTSD-----SETTT 455
Query: 380 LEQEEESAQRQKTAGKIFRAEASTGQDAPRQAQ-----------------ARSWASQGKA 422
E TAG + +TG + + A + S+ A
Sbjct: 456 ASTEGSETTTVTTAGSETKTAYTTGSETTTASNTGLETTTVFTIGSDTTTASTEGSETTA 515
Query: 423 ASAEGDE-----SEVSEHLSASSA-------SAIQQDSTSSMQPPSEAPMVNTV------ 464
SA G E +E SE+ + S+ S ++T++ SE V+T
Sbjct: 516 VSATGSEMTTVSTEGSENTTVSTTGSETTTVSTTGLETTTTSTEGSEMTTVSTTGAETTT 575
Query: 465 -----------SSAYSE-------DFENSPSLTASEPTAHSKESLDRTLDALSESSSSVK 506
S+A SE D EN+ + TA T + + T A S +SS
Sbjct: 576 DSTEGSGTTAASTAGSETTTVSTADSENTTASTADSETTSASTTGSETTTA-STTSSETT 634
Query: 507 TDLPQTAESRKKSGRHVTRVLVKDT 531
T + +E+ S +V T
Sbjct: 635 TASTEGSETTTVSTTDSETTMVSTT 659
Score = 34.3 bits (77), Expect = 0.37
Identities = 49/260 (18%), Positives = 88/260 (33%), Gaps = 11/260 (4%)
Query: 262 TVPSVELSSAKPSQTSHLPTSLAADRTLHSTRSRADYPQSHVSSDTASHTPSVSITGAFS 321
TV S+ + T+ T+ + +T + ++ S T S T VSI+G+
Sbjct: 6 TVAPAAGSNTTTASTTGSETTTILIKASETTTASTAGSETTTPSPTGSQTTIVSISGSEI 65
Query: 322 NSVSLKMGHVKLVSSPG--------RSEAETVDEPVSEGADDSLDEFRINILSLDGLAPA 373
+ S VSS G TV SE S+ ++S G
Sbjct: 66 TTTSTAGSENTTVSSAGSGTTTASMAGSETTVSTAGSETTTVSITGTETTMVSAMGSETT 125
Query: 374 VSENSDLEQEEES-AQRQKTAGKIFRAEASTGQDAPRQAQARSWASQGKAASAEGDESEV 432
+ + E S A + T +E +T A + A S +
Sbjct: 126 TNSTTSSETTVTSTAGSETTTVSTVGSETTTAYTADSETTAASTTGSEMTTVFTAGSETI 185
Query: 433 SEHLSASSASAIQQDSTSSMQPPSEAPMVNTVSSAYSEDFENSPSLTASEPTAHSKESLD 492
+ + S + + + + + T S+A+SE + S SE T S +
Sbjct: 186 TPSTAGSETTTVSTAGSETTTVSTTGSETTTASTAHSE--TTAASTMGSETTKVSTAGSE 243
Query: 493 RTLDALSESSSSVKTDLPQT 512
T+ +++ T+ +T
Sbjct: 244 TTVSTAGSETTAASTEDSET 263
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.307 0.121 0.323
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 24,045,578
Number of Sequences: 37866
Number of extensions: 1063378
Number of successful extensions: 5206
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 43
Number of HSP's successfully gapped in prelim test: 346
Number of HSP's that attempted gapping in prelim test: 4621
Number of HSP's gapped (non-prelim): 857
length of query: 657
length of database: 18,247,518
effective HSP length: 109
effective length of query: 548
effective length of database: 14,120,124
effective search space: 7737827952
effective search space used: 7737827952
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.7 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.