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Search of human proteins with 14149734
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|14149734 coronin, actin binding protein, 1B [Homo sapiens]
(489 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|65787364 coronin, actin binding protein, 1B [Homo sapiens] 996 0.0
gi|14149734 coronin, actin binding protein, 1B [Homo sapiens] 996 0.0
gi|7656991 coronin, actin binding protein, 1C isoform 1 [Homo sa... 757 0.0
gi|109627650 coronin 6 [Homo sapiens] 690 0.0
gi|5902134 coronin, actin binding protein, 1A [Homo sapiens] 659 0.0
gi|209529711 coronin, actin binding protein, 2A [Homo sapiens] 422 e-118
gi|16554585 coronin, actin binding protein, 2A [Homo sapiens] 422 e-118
gi|148529011 coronin, actin binding protein, 2B [Homo sapiens] 405 e-113
gi|168229161 coronin 7 [Homo sapiens] 235 8e-62
gi|207029439 retinoblastoma binding protein 4 isoform c [Homo sa... 70 3e-12
gi|207029415 retinoblastoma binding protein 4 isoform b [Homo sa... 70 3e-12
gi|5032027 retinoblastoma binding protein 4 isoform a [Homo sapi... 70 3e-12
gi|20143912 WD repeat and SOCS box-containing 1 isoform 2 [Homo ... 69 7e-12
gi|18677720 WD repeat and SOCS box-containing 1 isoform 1 [Homo ... 69 1e-11
gi|19913371 transducin (beta)-like 1 X-linked receptor 1 [Homo s... 65 2e-10
gi|4506439 retinoblastoma binding protein 7 [Homo sapiens] 64 3e-10
gi|55743149 WD repeat domain 17 isoform 2 [Homo sapiens] 63 7e-10
gi|31317311 WD repeat domain 17 isoform 1 [Homo sapiens] 63 7e-10
gi|7657381 PRP19/PSO4 pre-mRNA processing factor 19 homolog [Hom... 62 9e-10
gi|56243590 WD repeat domain 33 isoform 1 [Homo sapiens] 62 2e-09
gi|213021190 transducin beta-like 1X isoform b [Homo sapiens] 61 3e-09
gi|213021188 transducin beta-like 1X isoform b [Homo sapiens] 61 3e-09
gi|213021186 transducin beta-like 1X isoform a [Homo sapiens] 61 3e-09
gi|5032159 transducin beta-like 1X isoform a [Homo sapiens] 61 3e-09
gi|169403944 WD repeat domain 26 isoform b [Homo sapiens] 61 3e-09
gi|55743153 WD repeat domain 26 isoform a [Homo sapiens] 61 3e-09
gi|4505731 peroxisomal biogenesis factor 7 [Homo sapiens] 60 3e-09
gi|5902034 periodic tryptophan protein 1 [Homo sapiens] 60 6e-09
gi|19913367 transducin beta-like 1Y [Homo sapiens] 59 1e-08
gi|19913365 transducin beta-like 1Y [Homo sapiens] 59 1e-08
>gi|65787364 coronin, actin binding protein, 1B [Homo sapiens]
Length = 489
Score = 996 bits (2574), Expect = 0.0
Identities = 489/489 (100%), Positives = 489/489 (100%)
Query: 1 MSFRKVVRQSKFRHVFGQPVKNDQCYEDIRVSRVTWDSTFCAVNPKFLAVIVEASGGGAF 60
MSFRKVVRQSKFRHVFGQPVKNDQCYEDIRVSRVTWDSTFCAVNPKFLAVIVEASGGGAF
Sbjct: 1 MSFRKVVRQSKFRHVFGQPVKNDQCYEDIRVSRVTWDSTFCAVNPKFLAVIVEASGGGAF 60
Query: 61 LVLPLSKTGRIDKAYPTVCGHTGPVLDIDWCPHNDEVIASGSEDCTVMVWQIPENGLTSP 120
LVLPLSKTGRIDKAYPTVCGHTGPVLDIDWCPHNDEVIASGSEDCTVMVWQIPENGLTSP
Sbjct: 61 LVLPLSKTGRIDKAYPTVCGHTGPVLDIDWCPHNDEVIASGSEDCTVMVWQIPENGLTSP 120
Query: 121 LTEPVVVLEGHTKRVGIIAWHPTARNVLLSAGCDNVVLIWNVGTAEELYRLDSLHPDLIY 180
LTEPVVVLEGHTKRVGIIAWHPTARNVLLSAGCDNVVLIWNVGTAEELYRLDSLHPDLIY
Sbjct: 121 LTEPVVVLEGHTKRVGIIAWHPTARNVLLSAGCDNVVLIWNVGTAEELYRLDSLHPDLIY 180
Query: 181 NVSWNHNGSLFCSACKDKSVRIIDPRRGTLVAEREKAHEGARPMRAIFLADGKVFTTGFS 240
NVSWNHNGSLFCSACKDKSVRIIDPRRGTLVAEREKAHEGARPMRAIFLADGKVFTTGFS
Sbjct: 181 NVSWNHNGSLFCSACKDKSVRIIDPRRGTLVAEREKAHEGARPMRAIFLADGKVFTTGFS 240
Query: 241 RMSERQLALWDPENLEEPMALQELDSSNGALLPFYDPDTSVVYVCGKGDSSIRYFEITEE 300
RMSERQLALWDPENLEEPMALQELDSSNGALLPFYDPDTSVVYVCGKGDSSIRYFEITEE
Sbjct: 241 RMSERQLALWDPENLEEPMALQELDSSNGALLPFYDPDTSVVYVCGKGDSSIRYFEITEE 300
Query: 301 PPYIHFLNTFTSKEPQRGMGSMPKRGLEVSKCEIARFYKLHERKCEPIVMTVPRKSDLFQ 360
PPYIHFLNTFTSKEPQRGMGSMPKRGLEVSKCEIARFYKLHERKCEPIVMTVPRKSDLFQ
Sbjct: 301 PPYIHFLNTFTSKEPQRGMGSMPKRGLEVSKCEIARFYKLHERKCEPIVMTVPRKSDLFQ 360
Query: 361 DDLYPDTAGPEAALEAEEWVSGRDADPILISLREAYVPSKQRDLKISRRNVLSDSRPAMA 420
DDLYPDTAGPEAALEAEEWVSGRDADPILISLREAYVPSKQRDLKISRRNVLSDSRPAMA
Sbjct: 361 DDLYPDTAGPEAALEAEEWVSGRDADPILISLREAYVPSKQRDLKISRRNVLSDSRPAMA 420
Query: 421 PGSSHLGAPASTTTAADATPSGSLARAGEAGKLEEVMQELRALRALVKEQGDRICRLEEQ 480
PGSSHLGAPASTTTAADATPSGSLARAGEAGKLEEVMQELRALRALVKEQGDRICRLEEQ
Sbjct: 421 PGSSHLGAPASTTTAADATPSGSLARAGEAGKLEEVMQELRALRALVKEQGDRICRLEEQ 480
Query: 481 LGRMENGDA 489
LGRMENGDA
Sbjct: 481 LGRMENGDA 489
>gi|14149734 coronin, actin binding protein, 1B [Homo sapiens]
Length = 489
Score = 996 bits (2574), Expect = 0.0
Identities = 489/489 (100%), Positives = 489/489 (100%)
Query: 1 MSFRKVVRQSKFRHVFGQPVKNDQCYEDIRVSRVTWDSTFCAVNPKFLAVIVEASGGGAF 60
MSFRKVVRQSKFRHVFGQPVKNDQCYEDIRVSRVTWDSTFCAVNPKFLAVIVEASGGGAF
Sbjct: 1 MSFRKVVRQSKFRHVFGQPVKNDQCYEDIRVSRVTWDSTFCAVNPKFLAVIVEASGGGAF 60
Query: 61 LVLPLSKTGRIDKAYPTVCGHTGPVLDIDWCPHNDEVIASGSEDCTVMVWQIPENGLTSP 120
LVLPLSKTGRIDKAYPTVCGHTGPVLDIDWCPHNDEVIASGSEDCTVMVWQIPENGLTSP
Sbjct: 61 LVLPLSKTGRIDKAYPTVCGHTGPVLDIDWCPHNDEVIASGSEDCTVMVWQIPENGLTSP 120
Query: 121 LTEPVVVLEGHTKRVGIIAWHPTARNVLLSAGCDNVVLIWNVGTAEELYRLDSLHPDLIY 180
LTEPVVVLEGHTKRVGIIAWHPTARNVLLSAGCDNVVLIWNVGTAEELYRLDSLHPDLIY
Sbjct: 121 LTEPVVVLEGHTKRVGIIAWHPTARNVLLSAGCDNVVLIWNVGTAEELYRLDSLHPDLIY 180
Query: 181 NVSWNHNGSLFCSACKDKSVRIIDPRRGTLVAEREKAHEGARPMRAIFLADGKVFTTGFS 240
NVSWNHNGSLFCSACKDKSVRIIDPRRGTLVAEREKAHEGARPMRAIFLADGKVFTTGFS
Sbjct: 181 NVSWNHNGSLFCSACKDKSVRIIDPRRGTLVAEREKAHEGARPMRAIFLADGKVFTTGFS 240
Query: 241 RMSERQLALWDPENLEEPMALQELDSSNGALLPFYDPDTSVVYVCGKGDSSIRYFEITEE 300
RMSERQLALWDPENLEEPMALQELDSSNGALLPFYDPDTSVVYVCGKGDSSIRYFEITEE
Sbjct: 241 RMSERQLALWDPENLEEPMALQELDSSNGALLPFYDPDTSVVYVCGKGDSSIRYFEITEE 300
Query: 301 PPYIHFLNTFTSKEPQRGMGSMPKRGLEVSKCEIARFYKLHERKCEPIVMTVPRKSDLFQ 360
PPYIHFLNTFTSKEPQRGMGSMPKRGLEVSKCEIARFYKLHERKCEPIVMTVPRKSDLFQ
Sbjct: 301 PPYIHFLNTFTSKEPQRGMGSMPKRGLEVSKCEIARFYKLHERKCEPIVMTVPRKSDLFQ 360
Query: 361 DDLYPDTAGPEAALEAEEWVSGRDADPILISLREAYVPSKQRDLKISRRNVLSDSRPAMA 420
DDLYPDTAGPEAALEAEEWVSGRDADPILISLREAYVPSKQRDLKISRRNVLSDSRPAMA
Sbjct: 361 DDLYPDTAGPEAALEAEEWVSGRDADPILISLREAYVPSKQRDLKISRRNVLSDSRPAMA 420
Query: 421 PGSSHLGAPASTTTAADATPSGSLARAGEAGKLEEVMQELRALRALVKEQGDRICRLEEQ 480
PGSSHLGAPASTTTAADATPSGSLARAGEAGKLEEVMQELRALRALVKEQGDRICRLEEQ
Sbjct: 421 PGSSHLGAPASTTTAADATPSGSLARAGEAGKLEEVMQELRALRALVKEQGDRICRLEEQ 480
Query: 481 LGRMENGDA 489
LGRMENGDA
Sbjct: 481 LGRMENGDA 489
>gi|7656991 coronin, actin binding protein, 1C isoform 1 [Homo
sapiens]
Length = 474
Score = 757 bits (1954), Expect = 0.0
Identities = 350/481 (72%), Positives = 415/481 (86%), Gaps = 10/481 (2%)
Query: 4 RKVVRQSKFRHVFGQPVKNDQCYEDIRVSRVTWDSTFCAVNPKFLAVIVEASGGGAFLVL 63
R+VVRQSKFRHVFGQ VKNDQCY+DIRVSRVTWDS+FCAVNP+F+A+I+EASGGGAFLVL
Sbjct: 2 RRVVRQSKFRHVFGQAVKNDQCYDDIRVSRVTWDSSFCAVNPRFVAIIIEASGGGAFLVL 61
Query: 64 PLSKTGRIDKAYPTVCGHTGPVLDIDWCPHNDEVIASGSEDCTVMVWQIPENGLTSPLTE 123
PL KTGRIDK+YPTVCGHTGPVLDIDWCPHND+VIASGSEDCTVMVWQIPENGLT LTE
Sbjct: 62 PLHKTGRIDKSYPTVCGHTGPVLDIDWCPHNDQVIASGSEDCTVMVWQIPENGLTLSLTE 121
Query: 124 PVVVLEGHTKRVGIIAWHPTARNVLLSAGCDNVVLIWNVGTAEELYRLDSLHPDLIYNVS 183
PVV+LEGH+KRVGI+AWHPTARNVLLSAGCDN ++IWNVGT E L LD +H D+IYNVS
Sbjct: 122 PVVILEGHSKRVGIVAWHPTARNVLLSAGCDNAIIIWNVGTGEALINLDDMHSDMIYNVS 181
Query: 184 WNHNGSLFCSACKDKSVRIIDPRRGTLVAEREKAHEGARPMRAIFLADGKVFTTGFSRMS 243
WN NGSL C+A KDK VR+IDPR+ +VAE+EKAHEGARPMRAIFLADG VFTTGFSRMS
Sbjct: 182 WNRNGSLICTASKDKKVRVIDPRKQEIVAEKEKAHEGARPMRAIFLADGNVFTTGFSRMS 241
Query: 244 ERQLALWDPENLEEPMALQELDSSNGALLPFYDPDTSVVYVCGKGDSSIRYFEITEEPPY 303
ERQLALW+P+N++EP+AL E+D+SNG LLPFYDPDTS++Y+CGKGDSSIRYFEIT+E PY
Sbjct: 242 ERQLALWNPKNMQEPIALHEMDTSNGVLLPFYDPDTSIIYLCGKGDSSIRYFEITDESPY 301
Query: 304 IHFLNTFTSKEPQRGMGSMPKRGLEVSKCEIARFYKLHERKCEPIVMTVPRKSDLFQDDL 363
+H+LNTF+SKEPQRGMG MPKRGL+V+KCEIARF+KLHERKCEPI+MTVPRKSDLFQDDL
Sbjct: 302 VHYLNTFSSKEPQRGMGYMPKRGLDVNKCEIARFFKLHERKCEPIIMTVPRKSDLFQDDL 361
Query: 364 YPDTAGPEAALEAEEWVSGRDADPILISLREAYVPSKQRDLKISRRNVLSDSRPAMAPGS 423
YPDTAGPEAALEAEEW G++ADPILISL+ Y+P K RDLK+ ++N+L DS+P
Sbjct: 362 YPDTAGPEAALEAEEWFEGKNADPILISLKHGYIPGKNRDLKVVKKNIL-DSKPTANKKC 420
Query: 424 SHLGAPASTTTAADATPSGSLARAGEAGKLEEVMQELRALRALVKEQGDRICRLEEQLGR 483
+ P TT A KL+E+++E+++++ + Q +RI +LE+Q+ +
Sbjct: 421 DLISIPKKTTDTASVQ---------NEAKLDEILKEIKSIKDTICNQDERISKLEQQMAK 471
Query: 484 M 484
+
Sbjct: 472 I 472
>gi|109627650 coronin 6 [Homo sapiens]
Length = 472
Score = 690 bits (1780), Expect = 0.0
Identities = 326/484 (67%), Positives = 392/484 (80%), Gaps = 16/484 (3%)
Query: 4 RKVVRQSKFRHVFGQPVKNDQCYEDIRVSRVTWDSTFCAVNPKFLAVIVEASGGGAFLVL 63
R+VVRQSKFRHVFGQ K DQ YEDIRVS+VTWDS+FCAVNPKFLA+IVEA GGGAF+VL
Sbjct: 3 RRVVRQSKFRHVFGQAAKADQAYEDIRVSKVTWDSSFCAVNPKFLAIIVEAGGGGAFIVL 62
Query: 64 PLSKTGRIDKAYPTVCGHTGPVLDIDWCPHNDEVIASGSEDCTVMVWQIPENGLTSPLTE 123
PL+KTGR+DK YP V GHT PVLDIDWCPHND VIAS S+D T+MVWQIP+ +TE
Sbjct: 63 PLAKTGRVDKNYPLVTGHTAPVLDIDWCPHNDNVIASASDDTTIMVWQIPDYTPMRNITE 122
Query: 124 PVVVLEGHTKRVGIIAWHPTARNVLLSAGCDNVVLIWNVGTAEELYRLDSLHPDLIYNVS 183
P++ LEGH+KRVGI++WHPTARNVLLSAG DNV++IWNVGT E L LD +HPD+I++V
Sbjct: 123 PIITLEGHSKRVGILSWHPTARNVLLSAGGDNVIIIWNVGTGEVLLSLDDMHPDVIHSVC 182
Query: 184 WNHNGSLFCSACKDKSVRIIDPRRGTLVAEREKAHEGARPMRAIFLADGKVFTTGFSRMS 243
WN NGSL + CKDK++RIIDPR+G +VAER AHEG RPMRA+F G +FTTGF+RMS
Sbjct: 183 WNSNGSLLATTCKDKTLRIIDPRKGQVVAERFAAHEGMRPMRAVFTRQGHIFTTGFTRMS 242
Query: 244 ERQLALWDPENLEEPMALQELDSSNGALLPFYDPDTSVVYVCGKGDSSIRYFEITEEPPY 303
+R+L LWDP N EEP+ALQE+D+SNG LLPFYDPD+S+VY+CGKGDSSIRYFEIT+EPP+
Sbjct: 243 QRELGLWDPNNFEEPVALQEMDTSNGVLLPFYDPDSSIVYLCGKGDSSIRYFEITDEPPF 302
Query: 304 IHFLNTFTSKEPQRGMGSMPKRGLEVSKCEIARFYKLHERKCEPIVMTVPRKSDLFQDDL 363
+H+LNTF+SKEPQRGMG MPKRGL+VSKCEIARFYKLHERKCEPI+MTVPRKSDLFQDDL
Sbjct: 303 VHYLNTFSSKEPQRGMGFMPKRGLDVSKCEIARFYKLHERKCEPIIMTVPRKSDLFQDDL 362
Query: 364 YPDTAGPEAALEAEEWVSGRDADPILISLREAYVPSKQRDLKISRRNVLSDSRPAMAPGS 423
YPDT GPE ALEA+EW+SG+DA+P+LISLR+ YVP K R+L++++RN+L D RP P
Sbjct: 363 YPDTPGPEPALEADEWLSGQDAEPVLISLRDGYVPPKHRELRVTKRNIL-DVRPPSGPRR 421
Query: 424 SHLGAPASTTTAADATPSGSLARAGEAGKLEEVMQELRALRALVKEQGDRICRLEEQLGR 483
S S S A + LE +++E++ALR V+ Q RI LE L
Sbjct: 422 SQ---------------SASDAPLSQQHTLETLLEEIKALRERVQAQEQRITALENMLCE 466
Query: 484 MENG 487
+ +G
Sbjct: 467 LVDG 470
>gi|5902134 coronin, actin binding protein, 1A [Homo sapiens]
Length = 461
Score = 659 bits (1699), Expect = 0.0
Identities = 316/477 (66%), Positives = 385/477 (80%), Gaps = 24/477 (5%)
Query: 4 RKVVRQSKFRHVFGQPVKNDQCYEDIRVSRVTWDSTFCAVNPKFLAVIVEASGGGAFLVL 63
R+VVR SKFRHVFGQP K DQCYED+RVS+ TWDS FCAVNPKF+A+I EASGGGAFLVL
Sbjct: 3 RQVVRSSKFRHVFGQPAKADQCYEDVRVSQTTWDSGFCAVNPKFVALICEASGGGAFLVL 62
Query: 64 PLSKTGRIDKAYPTVCGHTGPVLDIDWCPHNDEVIASGSEDCTVMVWQIPENGLTSPLTE 123
PL KTGR+DK PTVCGHT PVLDI WCPHND VIASGSEDCTVMVW+IP+ GL PL E
Sbjct: 63 PLGKTGRVDKNAPTVCGHTAPVLDIAWCPHNDNVIASGSEDCTVMVWEIPDGGLMLPLRE 122
Query: 124 PVVVLEGHTKRVGIIAWHPTARNVLLSAGCDNVVLIWNVGTAEELYRLD-SLHPDLIYNV 182
PVV LEGHTKRVGI+AWH TA+NVLLSAGCDNV+++W+VGT + L +HPD IY+V
Sbjct: 123 PVVTLEGHTKRVGIVAWHTTAQNVLLSAGCDNVIMVWDVGTGAAMLTLGPEVHPDTIYSV 182
Query: 183 SWNHNGSLFCSACKDKSVRIIDPRRGTLVAEREKAHEGARPMRAIFLADGKVFTTGFSRM 242
W+ +G L C++C+DK VRII+PR+GT+VAE+++ HEG RP+RA+F+++GK+ TTGFSRM
Sbjct: 183 DWSRDGGLICTSCRDKRVRIIEPRKGTVVAEKDRPHEGTRPVRAVFVSEGKILTTGFSRM 242
Query: 243 SERQLALWDPENLEEPMALQELDSSNGALLPFYDPDTSVVYVCGKGDSSIRYFEITEEPP 302
SERQ+ALWD ++LEEP++LQELD+S+G LLPF+DPDT++VY+CGKGDSSIRYFEIT E P
Sbjct: 243 SERQVALWDTKHLEEPLSLQELDTSSGVLLPFFDPDTNIVYLCGKGDSSIRYFEITSEAP 302
Query: 303 YIHFLNTFTSKEPQRGMGSMPKRGLEVSKCEIARFYKLHERKCEPIVMTVPRKSDLFQDD 362
++H+L+ F+SKE QRGMG MPKRGLEV+KCEIARFYKLHER+CEPI MTVPRKSDLFQ+D
Sbjct: 303 FLHYLSMFSSKESQRGMGYMPKRGLEVNKCEIARFYKLHERRCEPIAMTVPRKSDLFQED 362
Query: 363 LYPDTAGPEAALEAEEWVSGRDADPILISLREAYVPSKQRDLKISRRNVLSDSRPAMAPG 422
LYP TAGP+ AL AEEW+ GRDA P+LISL++ YVP K R+L+++R L R AP
Sbjct: 363 LYPPTAGPDPALTAEEWLGGRDAGPLLISLKDGYVPPKSRELRVNRG--LDTGRRRAAP- 419
Query: 423 SSHLGAPASTTTAADATPSGSLARAGEAGKLEEVMQELRALRALVKEQGDRICRLEE 479
AS T ++DA +LEE E+R L+A V+E R+ RLEE
Sbjct: 420 ------EASGTPSSDA-----------VSRLEE---EMRKLQATVQELQKRLDRLEE 456
>gi|209529711 coronin, actin binding protein, 2A [Homo sapiens]
Length = 525
Score = 422 bits (1086), Expect = e-118
Identities = 215/454 (47%), Positives = 297/454 (65%), Gaps = 20/454 (4%)
Query: 1 MSFRKVVRQSKFRHVFGQPVKNDQCYEDIRVSRVTWDSTFCAVNPKFLAVIVEASGGGAF 60
MS+ R SKFRHVFG+P + CY+ + ++R D+ FCAVNP F+AV+ E +GGGAF
Sbjct: 1 MSWHPQYRSSKFRHVFGKPASKENCYDSVPITRSVHDNHFCAVNPHFIAVVTECAGGGAF 60
Query: 61 LVLPLSKTGRIDKAYPTVCGHTGPVLDIDWCPHNDEVIASGSEDCTVMVWQIPENGLTSP 120
LV+PL +TG++D YP VCGH G VLD+ W P +D IAS SED T+ +W IP+ LT
Sbjct: 61 LVIPLHQTGKLDPHYPKVCGHRGNVLDVKWNPFDDFEIASCSEDATIKIWSIPKQLLTRN 120
Query: 121 LTEPVVVLEGHTKRVGIIAWHPTARNVLLSAGCDNVVLIWNVGTAEELYRLD----SLHP 176
LT L GH +RVG++ WHPTA N+L SAG D V+IWN+ T E + S H
Sbjct: 121 LTAYRKELVGHARRVGLVEWHPTAANILFSAGYDYKVMIWNLDTKESVITSPMSTISCHQ 180
Query: 177 DLIYNVSWNHNGSLFCSACKDKSVRIIDPRRGTLVAEREKAHEGARPMRAIFLAD-GKVF 235
D+I ++S+N NGSL + CKD+ +R+IDPR GT++ +E +++G R + +FL + K+
Sbjct: 181 DVILSMSFNTNGSLLATTCKDRKIRVIDPRAGTVL--QEASYKGHRASKVLFLGNLKKLM 238
Query: 236 TTGFSRMSERQLALWDPENLEEPMALQELDSSNGALLPFYDPDTSVVYVCGKGDSSIRYF 295
+TG SR + RQ+ALWD +NL P+ ++LD S+G L PFYD DTS++YV GKGD +IRY+
Sbjct: 239 STGTSRWNNRQVALWDQDNLSVPLMEEDLDGSSGVLFPFYDADTSMLYVVGKGDGNIRYY 298
Query: 296 EITEEPPYIHFLNTFTSKEPQRGMGSMPKRGLEVSKCEIARFYKLHERK--CEPIVMTVP 353
E++ + P++ +L + S PQ+G+G MPKRGL+VS CEI RFYKL K EPI M VP
Sbjct: 299 EVSADKPHLSYLTEYRSYNPQKGIGVMPKRGLDVSSCEIFRFYKLITTKSLIEPISMIVP 358
Query: 354 RKSDLFQDDLYPDTAGPEAALEAEEWVSGRDADPILISLREAYVPSKQRDLKISRRNVLS 413
R+S+ +Q+D+YP TAG + +L A+EW+SG + DPIL+SLR ++ R + L
Sbjct: 359 RRSESYQEDIYPPTAGAQPSLTAQEWLSGMNRDPILVSLRPG--------SELLRPHPLP 410
Query: 414 DSRP---AMAPGSSHLGAPASTTTAADATPSGSL 444
RP +MAP S L A D S SL
Sbjct: 411 AERPIFNSMAPASPRLLNQTEKLAAEDGWRSSSL 444
>gi|16554585 coronin, actin binding protein, 2A [Homo sapiens]
Length = 525
Score = 422 bits (1086), Expect = e-118
Identities = 215/454 (47%), Positives = 297/454 (65%), Gaps = 20/454 (4%)
Query: 1 MSFRKVVRQSKFRHVFGQPVKNDQCYEDIRVSRVTWDSTFCAVNPKFLAVIVEASGGGAF 60
MS+ R SKFRHVFG+P + CY+ + ++R D+ FCAVNP F+AV+ E +GGGAF
Sbjct: 1 MSWHPQYRSSKFRHVFGKPASKENCYDSVPITRSVHDNHFCAVNPHFIAVVTECAGGGAF 60
Query: 61 LVLPLSKTGRIDKAYPTVCGHTGPVLDIDWCPHNDEVIASGSEDCTVMVWQIPENGLTSP 120
LV+PL +TG++D YP VCGH G VLD+ W P +D IAS SED T+ +W IP+ LT
Sbjct: 61 LVIPLHQTGKLDPHYPKVCGHRGNVLDVKWNPFDDFEIASCSEDATIKIWSIPKQLLTRN 120
Query: 121 LTEPVVVLEGHTKRVGIIAWHPTARNVLLSAGCDNVVLIWNVGTAEELYRLD----SLHP 176
LT L GH +RVG++ WHPTA N+L SAG D V+IWN+ T E + S H
Sbjct: 121 LTAYRKELVGHARRVGLVEWHPTAANILFSAGYDYKVMIWNLDTKESVITSPMSTISCHQ 180
Query: 177 DLIYNVSWNHNGSLFCSACKDKSVRIIDPRRGTLVAEREKAHEGARPMRAIFLAD-GKVF 235
D+I ++S+N NGSL + CKD+ +R+IDPR GT++ +E +++G R + +FL + K+
Sbjct: 181 DVILSMSFNTNGSLLATTCKDRKIRVIDPRAGTVL--QEASYKGHRASKVLFLGNLKKLM 238
Query: 236 TTGFSRMSERQLALWDPENLEEPMALQELDSSNGALLPFYDPDTSVVYVCGKGDSSIRYF 295
+TG SR + RQ+ALWD +NL P+ ++LD S+G L PFYD DTS++YV GKGD +IRY+
Sbjct: 239 STGTSRWNNRQVALWDQDNLSVPLMEEDLDGSSGVLFPFYDADTSMLYVVGKGDGNIRYY 298
Query: 296 EITEEPPYIHFLNTFTSKEPQRGMGSMPKRGLEVSKCEIARFYKLHERK--CEPIVMTVP 353
E++ + P++ +L + S PQ+G+G MPKRGL+VS CEI RFYKL K EPI M VP
Sbjct: 299 EVSADKPHLSYLTEYRSYNPQKGIGVMPKRGLDVSSCEIFRFYKLITTKSLIEPISMIVP 358
Query: 354 RKSDLFQDDLYPDTAGPEAALEAEEWVSGRDADPILISLREAYVPSKQRDLKISRRNVLS 413
R+S+ +Q+D+YP TAG + +L A+EW+SG + DPIL+SLR ++ R + L
Sbjct: 359 RRSESYQEDIYPPTAGAQPSLTAQEWLSGMNRDPILVSLRPG--------SELLRPHPLP 410
Query: 414 DSRP---AMAPGSSHLGAPASTTTAADATPSGSL 444
RP +MAP S L A D S SL
Sbjct: 411 AERPIFNSMAPASPRLLNQTEKLAAEDGWRSSSL 444
>gi|148529011 coronin, actin binding protein, 2B [Homo sapiens]
Length = 480
Score = 405 bits (1042), Expect = e-113
Identities = 200/409 (48%), Positives = 278/409 (67%), Gaps = 8/409 (1%)
Query: 1 MSFRKVVRQSKFRHVFGQPVKNDQCYEDIRVSRVTWDSTFCAVNPKFLAVIVEASGGGAF 60
MS+R R SKFR+V+G+ + C++ I +++ D+ FCAVN +FLA++ E++GGG+F
Sbjct: 6 MSWRPQYRSSKFRNVYGKVANREHCFDGIPITKNVHDNHFCAVNTRFLAIVTESAGGGSF 65
Query: 61 LVLPLSKTGRIDKAYPTVCGHTGPVLDIDWCPHNDEVIASGSEDCTVMVWQIPENGLTSP 120
LV+PL +TGRI+ YP VCGH G VLDI W P D +IAS SED +V +W+IPE GL
Sbjct: 66 LVIPLEQTGRIEPNYPKVCGHQGNVLDIKWNPFIDNIIASCSEDTSVRIWEIPEGGLKRN 125
Query: 121 LTEPVVVLEGHTKRVGIIAWHPTARNVLLSAGCDNVVLIWNVGTAEELYRLDSLHPDLIY 180
+TE ++ L GH++RVG++ WHPT N+L SAG D VLIWN+ E + +D H D+I
Sbjct: 126 MTEALLELHGHSRRVGLVEWHPTTNNILFSAGYDYKVLIWNLDVGEPVKMID-CHTDVIL 184
Query: 181 NVSWNHNGSLFCSACKDKSVRIIDPRRGTLVAERE-KAHEGARPMRAIFLADGK-VFTTG 238
+S+N +GSL + CKDK +R+I+PR G ++ E K H R R +FL + K + TTG
Sbjct: 185 CMSFNTDGSLLTTTCKDKKLRVIEPRSGRVLQEANCKNH---RVNRVVFLGNMKRLLTTG 241
Query: 239 FSRMSERQLALWDPENLEEPMALQELDSSNGALLPFYDPDTSVVYVCGKGDSSIRYFEIT 298
SR + RQ+ALWD E+L P+ +E+D +G L PFYD DT ++Y+ GKGD +IRY+EI+
Sbjct: 242 VSRWNTRQIALWDQEDLSMPLIEEEIDGLSGLLFPFYDADTHMLYLAGKGDGNIRYYEIS 301
Query: 299 EEPPYIHFLNTFTSKEPQRGMGSMPKRGLEVSKCEIARFYKLHERK--CEPIVMTVPRKS 356
E PY+ +L F S PQ+G+G MPK GL+VS CE+ RFYKL K EPI M VPR+S
Sbjct: 302 TEKPYLSYLMEFRSPAPQKGLGVMPKHGLDVSACEVFRFYKLVTLKGLIEPISMIVPRRS 361
Query: 357 DLFQDDLYPDTAGPEAALEAEEWVSGRDADPILISLREAYVPSKQRDLK 405
D +Q+D+YP T G E AL +EW+ G + DP+L+SL+E Y S + K
Sbjct: 362 DSYQEDIYPMTPGTEPALTPDEWLGGINRDPVLMSLKEGYKKSSKMVFK 410
>gi|168229161 coronin 7 [Homo sapiens]
Length = 925
Score = 235 bits (599), Expect = 8e-62
Identities = 138/392 (35%), Positives = 212/392 (54%), Gaps = 12/392 (3%)
Query: 10 SKFRHVFGQPVKNDQCYEDIRVSRVTWDST---FCAVNPKFLAVIVEASGGGAFLVLPLS 66
SKFRH G + D +++ +T FCA K + S GG VL L
Sbjct: 471 SKFRHAQGTVLHRDSHITNLKGLNLTTPGESDGFCA--NKLRVAVPLLSSGGQVAVLELR 528
Query: 67 KTGRI-DKAYPTVCGHTGPVLDIDWCPHNDEVIASGSEDCTVMVWQIPENGLTSPLTEPV 125
K GR+ D A PT+ + V D+ W P + +A ED + +W++P GL LT P
Sbjct: 529 KPGRLPDTALPTL-QNGAAVTDLAWDPFDPHRLAVAGEDARIRLWRVPAEGLEEVLTTPE 587
Query: 126 VVLEGHTKRVGIIAWHPTARNVLLSAGCDNVVLIWNVGTAEELYRLDSLHPDLIYNVSWN 185
VL GHT+++ + +HP A NVL S+ D V IW++ + +L H D I++++W+
Sbjct: 588 TVLTGHTEKICSLRFHPLAANVLASSSYDLTVRIWDLQAGADRLKLQG-HQDQIFSLAWS 646
Query: 186 HNGSLFCSACKDKSVRIIDPRRGTLVAEREKAHEGARPMRAIFLADGK-VFTTGFSRMSE 244
+G + CKD VR+ PR G + +G R R +++ DG+ + +GF SE
Sbjct: 647 PDGQQLATVCKDGRVRVYRPRSGPEPLQEGPGPKGGRGARIVWVCDGRCLLVSGFDSQSE 706
Query: 245 RQLALWDPENLEE-PMALQELDSSNGALLPFYDPDTSVVYVCGKGDSSIRYFEITEEPPY 303
RQL L++ E L P+A+ LD + LLP YDPDT +V + GKGD+ + +E+ E P+
Sbjct: 707 RQLLLYEAEALAGGPLAVLGLDVAPSTLLPSYDPDTGLVLLTGKGDTRVFLYELLPESPF 766
Query: 304 IHFLNTFTSKEPQRGMGSMPKRGLEVSKCEIARFYKLHERKCEPIVMTVPR-KSDLFQDD 362
N+FTS +P +G+ +PK +V + E+ R +L + EP+ +PR + + FQDD
Sbjct: 767 FLECNSFTSPDPHKGLVLLPKTECDVREVELMRCLRLRQSSLEPVAFRLPRVRKEFFQDD 826
Query: 363 LYPDTAGP-EAALEAEEWVSGRDADPILISLR 393
++PDTA E L AE W+ G + P L+SL+
Sbjct: 827 VFPDTAVIWEPVLSAEAWLQGANGQPWLLSLQ 858
Score = 205 bits (522), Expect = 7e-53
Identities = 122/392 (31%), Positives = 201/392 (51%), Gaps = 6/392 (1%)
Query: 8 RQSKFRHVFGQPVKNDQCYEDIRVSRVTWDSTFCAVNPKFLAVIVEASGGGAFLVLPLSK 67
R SKFRH +P + + DIR T S + + + G ++PL
Sbjct: 5 RVSKFRHTEARPPRRESWISDIRAG--TAPSCRNHIKSSCSLIAFNSDRPGVLGIVPLQG 62
Query: 68 TGRIDKAYPTVCGHTGPVLDIDWCPHNDEVIASGSEDCTVMVWQIPENGLTSPLTEPVVV 127
G + + H+ V D+D+ P +D ++A+GS D TV +W++P G P + P VV
Sbjct: 63 QGEDKRRVAHLGCHSDLVTDLDFSPFDDFLLATGSADRTVKLWRLPGPGQALP-SAPGVV 121
Query: 128 LEGHTKRVGIIAWHPTARNVLLSAGCDNVVLIWNVGTAEELYRLDSLHPDLIYNVSWNHN 187
L V ++ +HPT+ +L+SA V +W+ + L L + H DL+ + W+ +
Sbjct: 122 LGPEDLPVEVLQFHPTSDGILVSAA-GTTVKVWDAAKQQPLTEL-AAHGDLVQSAVWSRD 179
Query: 188 GSLFCSACKDKSVRIIDPRRGTLVAEREKAHEGARPMRAIFLADGK-VFTTGFSRMSERQ 246
G+L +ACKDK +RI DPR ++ +AHE +R R ++ + + +TGF++M ER+
Sbjct: 180 GALVGTACKDKQLRIFDPRTKPRASQSTQAHENSRDSRLAWMGTWEHLVSTGFNQMRERE 239
Query: 247 LALWDPENLEEPMALQELDSSNGALLPFYDPDTSVVYVCGKGDSSIRYFEITEEPPYIHF 306
+ LWD +A LD+S G L+P DPD+ ++ + GKG+ + +E+ + P +
Sbjct: 240 VKLWDTRFFSSALASLTLDTSLGCLVPLLDPDSGLLVLAGKGERQLYCYEVVPQQPALSP 299
Query: 307 LNTFTSKEPQRGMGSMPKRGLEVSKCEIARFYKLHERKCEPIVMTVPRKSDLFQDDLYPD 366
+ + RG +P++ L V CE+ R +L + PI VPRK+ F +DL+PD
Sbjct: 300 VTQCVLESVLRGAALVPRQALAVMSCEVLRVLQLSDTAIVPIGYHVPRKAVEFHEDLFPD 359
Query: 367 TAGPEAALEAEEWVSGRDADPILISLREAYVP 398
TAG A + W +G + +SL A P
Sbjct: 360 TAGCVPATDPHSWWAGDNQQVQKVSLNPACRP 391
>gi|207029439 retinoblastoma binding protein 4 isoform c [Homo
sapiens]
Length = 390
Score = 70.5 bits (171), Expect = 3e-12
Identities = 50/220 (22%), Positives = 100/220 (45%), Gaps = 12/220 (5%)
Query: 18 QPVKNDQCYEDIRVSRVTWDSTFCAVNPKFLAVIVEASGGGAFLVLPLS---KTGRIDKA 74
+P + +C D+R+ + + NP ++ AS + +S K G++ A
Sbjct: 125 KPDPSGECNPDLRLRGHQKEGYGLSWNPNLSGHLLSASDDHTICLWDISAVPKEGKVVDA 184
Query: 75 YPTVCGHTGPVLDIDWCPHNDEVIASGSEDCTVMVWQIPENGLTSPLTEPVVVLEGHTKR 134
GHT V D+ W ++ + S ++D +M+W N + P ++ HT
Sbjct: 185 KTIFTGHTAVVEDVSWHLLHESLFGSVADDQKLMIWDTRSNNTSKPSHS----VDAHTAE 240
Query: 135 VGIIAWHPTARNVLLSAGCDNVVLIWNVGTAE-ELYRLDSLHPDLIYNVSWN-HNGSLFC 192
V ++++P + +L + D V +W++ + +L+ +S H D I+ V W+ HN ++
Sbjct: 241 VNCLSFNPYSEFILATGSADKTVALWDLRNLKLKLHSFES-HKDEIFQVQWSPHNETILA 299
Query: 193 SACKDKSVRIIDPRRGTLVAEREKAHEGARPMRAIFLADG 232
S+ D+ + + D + E A +G P +F+ G
Sbjct: 300 SSGTDRRLNVWDLSKIGEEQSPEDAEDG--PPELLFIHGG 337
Score = 54.7 bits (130), Expect = 2e-07
Identities = 28/97 (28%), Positives = 47/97 (48%), Gaps = 11/97 (11%)
Query: 81 HTGPVLDIDWCPHNDEVIASGSEDCTVMVW--------QIPENGLTSPLTEPVVVLEGHT 132
H + + W PHN+ ++AS D + VW Q PE+ P E + + GHT
Sbjct: 281 HKDEIFQVQWSPHNETILASSGTDRRLNVWDLSKIGEEQSPEDAEDGP-PELLFIHGGHT 339
Query: 133 KRVGIIAWHPTARNVLLSAGCDNVVLIWNVGTAEELY 169
++ +W+P V+ S DN++ +W + AE +Y
Sbjct: 340 AKISDFSWNPNEPWVICSVSEDNIMQVWQM--AENIY 374
Score = 49.3 bits (116), Expect = 8e-06
Identities = 44/213 (20%), Positives = 89/213 (41%), Gaps = 20/213 (9%)
Query: 80 GHTGPVLDIDWCPHNDEVIASGSEDCTVMVWQIPENGLTSPLTEPVVVLEGHTKRVGIIA 139
GH + W P+ + S S+D T+ +W I + + + GHT V ++
Sbjct: 140 GHQKEGYGLSWNPNLSGHLLSASDDHTICLWDISAVPKEGKVVDAKTIFTGHTAVVEDVS 199
Query: 140 WHPTARNVLLSAGCDNVVLIWNV---GTAEELYRLDSLHPDLIYNVSWN-HNGSLFCSAC 195
WH ++ S D ++IW+ T++ + +D+ H + +S+N ++ + +
Sbjct: 200 WHLLHESLFGSVADDQKLMIWDTRSNNTSKPSHSVDA-HTAEVNCLSFNPYSEFILATGS 258
Query: 196 KDKSVRIIDPRRGTLVAEREKAHEGA------RPMRAIFLADGKVFTTGFSRMSERQLAL 249
DK+V + D R L ++H+ P LA S ++R+L +
Sbjct: 259 ADKTVALWDLRNLKLKLHSFESHKDEIFQVQWSPHNETILA---------SSGTDRRLNV 309
Query: 250 WDPENLEEPMALQELDSSNGALLPFYDPDTSVV 282
WD + E + ++ + LL + T+ +
Sbjct: 310 WDLSKIGEEQSPEDAEDGPPELLFIHGGHTAKI 342
Score = 38.9 bits (89), Expect = 0.011
Identities = 17/36 (47%), Positives = 21/36 (58%)
Query: 80 GHTGPVLDIDWCPHNDEVIASGSEDCTVMVWQIPEN 115
GHT + D W P+ VI S SED + VWQ+ EN
Sbjct: 337 GHTAKISDFSWNPNEPWVICSVSEDNIMQVWQMAEN 372
>gi|207029415 retinoblastoma binding protein 4 isoform b [Homo
sapiens]
Length = 424
Score = 70.5 bits (171), Expect = 3e-12
Identities = 50/220 (22%), Positives = 100/220 (45%), Gaps = 12/220 (5%)
Query: 18 QPVKNDQCYEDIRVSRVTWDSTFCAVNPKFLAVIVEASGGGAFLVLPLS---KTGRIDKA 74
+P + +C D+R+ + + NP ++ AS + +S K G++ A
Sbjct: 159 KPDPSGECNPDLRLRGHQKEGYGLSWNPNLSGHLLSASDDHTICLWDISAVPKEGKVVDA 218
Query: 75 YPTVCGHTGPVLDIDWCPHNDEVIASGSEDCTVMVWQIPENGLTSPLTEPVVVLEGHTKR 134
GHT V D+ W ++ + S ++D +M+W N + P ++ HT
Sbjct: 219 KTIFTGHTAVVEDVSWHLLHESLFGSVADDQKLMIWDTRSNNTSKPSHS----VDAHTAE 274
Query: 135 VGIIAWHPTARNVLLSAGCDNVVLIWNVGTAE-ELYRLDSLHPDLIYNVSWN-HNGSLFC 192
V ++++P + +L + D V +W++ + +L+ +S H D I+ V W+ HN ++
Sbjct: 275 VNCLSFNPYSEFILATGSADKTVALWDLRNLKLKLHSFES-HKDEIFQVQWSPHNETILA 333
Query: 193 SACKDKSVRIIDPRRGTLVAEREKAHEGARPMRAIFLADG 232
S+ D+ + + D + E A +G P +F+ G
Sbjct: 334 SSGTDRRLNVWDLSKIGEEQSPEDAEDG--PPELLFIHGG 371
Score = 54.7 bits (130), Expect = 2e-07
Identities = 28/97 (28%), Positives = 47/97 (48%), Gaps = 11/97 (11%)
Query: 81 HTGPVLDIDWCPHNDEVIASGSEDCTVMVW--------QIPENGLTSPLTEPVVVLEGHT 132
H + + W PHN+ ++AS D + VW Q PE+ P E + + GHT
Sbjct: 315 HKDEIFQVQWSPHNETILASSGTDRRLNVWDLSKIGEEQSPEDAEDGP-PELLFIHGGHT 373
Query: 133 KRVGIIAWHPTARNVLLSAGCDNVVLIWNVGTAEELY 169
++ +W+P V+ S DN++ +W + AE +Y
Sbjct: 374 AKISDFSWNPNEPWVICSVSEDNIMQVWQM--AENIY 408
Score = 49.3 bits (116), Expect = 8e-06
Identities = 44/213 (20%), Positives = 89/213 (41%), Gaps = 20/213 (9%)
Query: 80 GHTGPVLDIDWCPHNDEVIASGSEDCTVMVWQIPENGLTSPLTEPVVVLEGHTKRVGIIA 139
GH + W P+ + S S+D T+ +W I + + + GHT V ++
Sbjct: 174 GHQKEGYGLSWNPNLSGHLLSASDDHTICLWDISAVPKEGKVVDAKTIFTGHTAVVEDVS 233
Query: 140 WHPTARNVLLSAGCDNVVLIWNV---GTAEELYRLDSLHPDLIYNVSWN-HNGSLFCSAC 195
WH ++ S D ++IW+ T++ + +D+ H + +S+N ++ + +
Sbjct: 234 WHLLHESLFGSVADDQKLMIWDTRSNNTSKPSHSVDA-HTAEVNCLSFNPYSEFILATGS 292
Query: 196 KDKSVRIIDPRRGTLVAEREKAHEGA------RPMRAIFLADGKVFTTGFSRMSERQLAL 249
DK+V + D R L ++H+ P LA S ++R+L +
Sbjct: 293 ADKTVALWDLRNLKLKLHSFESHKDEIFQVQWSPHNETILA---------SSGTDRRLNV 343
Query: 250 WDPENLEEPMALQELDSSNGALLPFYDPDTSVV 282
WD + E + ++ + LL + T+ +
Sbjct: 344 WDLSKIGEEQSPEDAEDGPPELLFIHGGHTAKI 376
Score = 38.9 bits (89), Expect = 0.011
Identities = 17/36 (47%), Positives = 21/36 (58%)
Query: 80 GHTGPVLDIDWCPHNDEVIASGSEDCTVMVWQIPEN 115
GHT + D W P+ VI S SED + VWQ+ EN
Sbjct: 371 GHTAKISDFSWNPNEPWVICSVSEDNIMQVWQMAEN 406
>gi|5032027 retinoblastoma binding protein 4 isoform a [Homo
sapiens]
Length = 425
Score = 70.5 bits (171), Expect = 3e-12
Identities = 50/220 (22%), Positives = 100/220 (45%), Gaps = 12/220 (5%)
Query: 18 QPVKNDQCYEDIRVSRVTWDSTFCAVNPKFLAVIVEASGGGAFLVLPLS---KTGRIDKA 74
+P + +C D+R+ + + NP ++ AS + +S K G++ A
Sbjct: 160 KPDPSGECNPDLRLRGHQKEGYGLSWNPNLSGHLLSASDDHTICLWDISAVPKEGKVVDA 219
Query: 75 YPTVCGHTGPVLDIDWCPHNDEVIASGSEDCTVMVWQIPENGLTSPLTEPVVVLEGHTKR 134
GHT V D+ W ++ + S ++D +M+W N + P ++ HT
Sbjct: 220 KTIFTGHTAVVEDVSWHLLHESLFGSVADDQKLMIWDTRSNNTSKPSHS----VDAHTAE 275
Query: 135 VGIIAWHPTARNVLLSAGCDNVVLIWNVGTAE-ELYRLDSLHPDLIYNVSWN-HNGSLFC 192
V ++++P + +L + D V +W++ + +L+ +S H D I+ V W+ HN ++
Sbjct: 276 VNCLSFNPYSEFILATGSADKTVALWDLRNLKLKLHSFES-HKDEIFQVQWSPHNETILA 334
Query: 193 SACKDKSVRIIDPRRGTLVAEREKAHEGARPMRAIFLADG 232
S+ D+ + + D + E A +G P +F+ G
Sbjct: 335 SSGTDRRLNVWDLSKIGEEQSPEDAEDG--PPELLFIHGG 372
Score = 54.7 bits (130), Expect = 2e-07
Identities = 28/97 (28%), Positives = 47/97 (48%), Gaps = 11/97 (11%)
Query: 81 HTGPVLDIDWCPHNDEVIASGSEDCTVMVW--------QIPENGLTSPLTEPVVVLEGHT 132
H + + W PHN+ ++AS D + VW Q PE+ P E + + GHT
Sbjct: 316 HKDEIFQVQWSPHNETILASSGTDRRLNVWDLSKIGEEQSPEDAEDGP-PELLFIHGGHT 374
Query: 133 KRVGIIAWHPTARNVLLSAGCDNVVLIWNVGTAEELY 169
++ +W+P V+ S DN++ +W + AE +Y
Sbjct: 375 AKISDFSWNPNEPWVICSVSEDNIMQVWQM--AENIY 409
Score = 49.3 bits (116), Expect = 8e-06
Identities = 44/213 (20%), Positives = 89/213 (41%), Gaps = 20/213 (9%)
Query: 80 GHTGPVLDIDWCPHNDEVIASGSEDCTVMVWQIPENGLTSPLTEPVVVLEGHTKRVGIIA 139
GH + W P+ + S S+D T+ +W I + + + GHT V ++
Sbjct: 175 GHQKEGYGLSWNPNLSGHLLSASDDHTICLWDISAVPKEGKVVDAKTIFTGHTAVVEDVS 234
Query: 140 WHPTARNVLLSAGCDNVVLIWNV---GTAEELYRLDSLHPDLIYNVSWN-HNGSLFCSAC 195
WH ++ S D ++IW+ T++ + +D+ H + +S+N ++ + +
Sbjct: 235 WHLLHESLFGSVADDQKLMIWDTRSNNTSKPSHSVDA-HTAEVNCLSFNPYSEFILATGS 293
Query: 196 KDKSVRIIDPRRGTLVAEREKAHEGA------RPMRAIFLADGKVFTTGFSRMSERQLAL 249
DK+V + D R L ++H+ P LA S ++R+L +
Sbjct: 294 ADKTVALWDLRNLKLKLHSFESHKDEIFQVQWSPHNETILA---------SSGTDRRLNV 344
Query: 250 WDPENLEEPMALQELDSSNGALLPFYDPDTSVV 282
WD + E + ++ + LL + T+ +
Sbjct: 345 WDLSKIGEEQSPEDAEDGPPELLFIHGGHTAKI 377
Score = 38.9 bits (89), Expect = 0.011
Identities = 17/36 (47%), Positives = 21/36 (58%)
Query: 80 GHTGPVLDIDWCPHNDEVIASGSEDCTVMVWQIPEN 115
GHT + D W P+ VI S SED + VWQ+ EN
Sbjct: 372 GHTAKISDFSWNPNEPWVICSVSEDNIMQVWQMAEN 407
>gi|20143912 WD repeat and SOCS box-containing 1 isoform 2 [Homo
sapiens]
Length = 275
Score = 69.3 bits (168), Expect = 7e-12
Identities = 62/242 (25%), Positives = 103/242 (42%), Gaps = 15/242 (6%)
Query: 71 IDKAYPTVCGHTGPVLDIDWCPHNDEVIASGSEDCTVMVWQIPENGLTSPLTEPVVVLEG 130
I K + HT V D+ + P ++ S S D T+ VW + ++G + VL G
Sbjct: 13 IGKLLLNLVDHTEVVRDLTFAPDGSLILVSASRDKTLRVWDLKDDG------NMMKVLRG 66
Query: 131 HTKRVGIIAWHPTARNVLLSAGCDNVVLIWNVGTAEELYRLDSLHPDLIYNVSWNHNGSL 190
H V A+ P + ++L S G V +WN+ + +L+ H D++ ++ +G+L
Sbjct: 67 HQNWVYSCAFSPDS-SMLCSVGASKAVFLWNMDKYTMIRKLEGHHHDVV-ACDFSPDGAL 124
Query: 191 FCSACKDKSVRIIDPRRGTLVAEREKAHEGARPMRAIFLADGKVFTTGFSRMSERQLALW 250
+A D V I DP G ++ E P+ A D V + FS +L
Sbjct: 125 LATASYDTRVYIWDPHNGDILMEFGHLFPPPTPIFAGGANDRWVRSVSFSHDGLHVASLA 184
Query: 251 DPE-----NLEEPMALQELDSSNGALLPFYDPDTSVVYVCGKGDSSIRYFEITEEPPYIH 305
D + ++E +Q SNG F D SV+ G D S+ ++ + P +
Sbjct: 185 DDKMVRFWRIDEDYPVQVAPLSNGLCCAF-STDGSVL-AAGTHDGSVYFWATPRQVPSLQ 242
Query: 306 FL 307
L
Sbjct: 243 HL 244
>gi|18677720 WD repeat and SOCS box-containing 1 isoform 1 [Homo
sapiens]
Length = 421
Score = 68.6 bits (166), Expect = 1e-11
Identities = 60/232 (25%), Positives = 100/232 (43%), Gaps = 15/232 (6%)
Query: 81 HTGPVLDIDWCPHNDEVIASGSEDCTVMVWQIPENGLTSPLTEPVVVLEGHTKRVGIIAW 140
HT V D+ + P ++ S S D T+ VW + ++G + VL GH V A+
Sbjct: 169 HTEVVRDLTFAPDGSLILVSASRDKTLRVWDLKDDG------NMMKVLRGHQNWVYSCAF 222
Query: 141 HPTARNVLLSAGCDNVVLIWNVGTAEELYRLDSLHPDLIYNVSWNHNGSLFCSACKDKSV 200
P + ++L S G V +WN+ + +L+ H D++ ++ +G+L +A D V
Sbjct: 223 SPDS-SMLCSVGASKAVFLWNMDKYTMIRKLEGHHHDVV-ACDFSPDGALLATASYDTRV 280
Query: 201 RIIDPRRGTLVAEREKAHEGARPMRAIFLADGKVFTTGFSRMSERQLALWDPE-----NL 255
I DP G ++ E P+ A D V + FS +L D + +
Sbjct: 281 YIWDPHNGDILMEFGHLFPPPTPIFAGGANDRWVRSVSFSHDGLHVASLADDKMVRFWRI 340
Query: 256 EEPMALQELDSSNGALLPFYDPDTSVVYVCGKGDSSIRYFEITEEPPYIHFL 307
+E +Q SNG F D SV+ G D S+ ++ + P + L
Sbjct: 341 DEDYPVQVAPLSNGLCCAF-STDGSVL-AAGTHDGSVYFWATPRQVPSLQHL 390
Score = 48.9 bits (115), Expect = 1e-05
Identities = 32/158 (20%), Positives = 73/158 (46%), Gaps = 12/158 (7%)
Query: 97 VIASGSEDCTVMVWQIPENGLTSPLTEPVVVLEGHTKRVGIIAWHPTARNVLLSAGCDNV 156
++A+G + + +W + L L + HT+ V + + P +L+SA D
Sbjct: 142 LLATGLNNGRIKIWDVYTGKLLLNLVD-------HTEVVRDLTFAPDGSLILVSASRDKT 194
Query: 157 VLIWNVGTAEELYRLDSLHPDLIYNVSWNHNGSLFCSACKDKSVRIIDPRRGTLVAEREK 216
+ +W++ + ++ H + +Y+ +++ + S+ CS K+V + + + T++ + E
Sbjct: 195 LRVWDLKDDGNMMKVLRGHQNWVYSCAFSPDSSMLCSVGASKAVFLWNMDKYTMIRKLEG 254
Query: 217 AHEGARPMRAIFLADGKVFTTGFSRMSERQLALWDPEN 254
H + F DG + T + ++ +WDP N
Sbjct: 255 HHHDV--VACDFSPDGALLATA---SYDTRVYIWDPHN 287
>gi|19913371 transducin (beta)-like 1 X-linked receptor 1 [Homo
sapiens]
Length = 514
Score = 64.7 bits (156), Expect = 2e-10
Identities = 51/181 (28%), Positives = 81/181 (44%), Gaps = 27/181 (14%)
Query: 68 TGRIDKAYPTVCGHTGPVLDIDWCPHNDEVIASGSEDCTVMVWQIPENGLTSPLTEPVVV 127
TG + +P H+ P LD+DW +N AS S D + V ++ ++ P+
Sbjct: 297 TGEAKQQFPF---HSAPALDVDWQSNN--TFASCSTDMCIHVCKLGQD-------RPIKT 344
Query: 128 LEGHTKRVGIIAWHPTARNVLLSAGCDNVVLIWNVGTAEELYRLDSLHPDLIYNVSWNHN 187
+GHT V I W PT N+L S D + IW++ ++ L + H IY + W+
Sbjct: 345 FQGHTNEVNAIKWDPTG-NLLASCSDDMTLKIWSMKQDNCVHDLQA-HNKEIYTIKWSPT 402
Query: 188 GS---------LFCSACKDKSVRIIDPRRGTLVAEREKAHEGARPMRAI-FLADGKVFTT 237
G + SA D +VR+ D RG + K E P+ ++ F DG+ +
Sbjct: 403 GPGTNNPNANLMLASASFDSTVRLWDVDRGICIHTLTKHQE---PVYSVAFSPDGRYLAS 459
Query: 238 G 238
G
Sbjct: 460 G 460
Score = 45.8 bits (107), Expect = 9e-05
Identities = 43/138 (31%), Positives = 59/138 (42%), Gaps = 15/138 (10%)
Query: 80 GHTGPVLDIDWCPHNDEVIASGSEDCTVMVWQIPENGLTSPLTEPVV---VLEG-----H 131
GH V W P +D ++ASGS D T +W + EN TS T+ V+ + EG
Sbjct: 167 GHESEVFICAWNPVSD-LLASGSGDSTARIWNLSENS-TSGSTQLVLRHCIREGGQDVPS 224
Query: 132 TKRVGIIAWHPTARNVLLSAGC-DNVVLIWNVGTAEELYRLDSLHPDLIYNVSWNHNGSL 190
K V + W+ + LL+ G D IW L H I+ + WN G+
Sbjct: 225 NKDVTSLDWN--SEGTLLATGSYDGFARIWT--KDGNLASTLGQHKGPIFALKWNKKGNF 280
Query: 191 FCSACKDKSVRIIDPRRG 208
SA DK+ I D G
Sbjct: 281 ILSAGVDKTTIIWDAHTG 298
Score = 44.7 bits (104), Expect = 2e-04
Identities = 42/185 (22%), Positives = 69/185 (37%), Gaps = 58/185 (31%)
Query: 72 DKAYPTVCGHTGPVLDIDWCPHNDEVIASGSEDCTVMVWQIPENGLTSPLTEPVVVLEGH 131
D+ T GHT V I W P + ++AS S+D T+ +W + ++ L + H
Sbjct: 339 DRPIKTFQGHTNEVNAIKWDPTGN-LLASCSDDMTLKIWSMKQDNCVHDL-------QAH 390
Query: 132 TKRVGIIAWHPT--------ARNVLLSAGCDNVVLIWNVGTAEELYRLDSLHPDLIYNVS 183
K + I W PT A +L SA D+ V +W+V ++ L H + +Y+V+
Sbjct: 391 NKEIYTIKWSPTGPGTNNPNANLMLASASFDSTVRLWDVDRGICIHTLTK-HQEPVYSVA 449
Query: 184 -----------------------------------------WNHNGSLFCSACKDKSVRI 202
WN G ++ D SV +
Sbjct: 450 FSPDGRYLASGSFDKCVHIWNTQTGALVHSYRGTGGIFEVCWNAAGDKVGASASDGSVCV 509
Query: 203 IDPRR 207
+D R+
Sbjct: 510 LDLRK 514
Score = 37.7 bits (86), Expect = 0.024
Identities = 32/120 (26%), Positives = 50/120 (41%), Gaps = 16/120 (13%)
Query: 85 VLDIDWCPHNDE--VIASGSEDCTVMVWQIPENGLTSPLTEPVVVLEGHTKRVGIIAWHP 142
V +DW N E ++A+GS D +W + L S L + H + + W+
Sbjct: 228 VTSLDW---NSEGTLLATGSYDGFARIWT-KDGNLASTLGQ-------HKGPIFALKWNK 276
Query: 143 TARNVLLSAGCDNVVLIWNVGTAEELYRLDSLHPDLIYNVSWNHNGSLFCSACKDKSVRI 202
N +LSAG D +IW+ T E + H +V W N + F S D + +
Sbjct: 277 KG-NFILSAGVDKTTIIWDAHTGEAKQQF-PFHSAPALDVDWQSNNT-FASCSTDMCIHV 333
Score = 35.4 bits (80), Expect = 0.12
Identities = 26/90 (28%), Positives = 40/90 (44%), Gaps = 14/90 (15%)
Query: 126 VVLEGHTKRVGIIAWHPTARNVLLSAGCDNVVLIWNV------GTAEELYR-------LD 172
VVL GH V I AW+P + ++L S D+ IWN+ G+ + + R D
Sbjct: 163 VVLRGHESEVFICAWNPVS-DLLASGSGDSTARIWNLSENSTSGSTQLVLRHCIREGGQD 221
Query: 173 SLHPDLIYNVSWNHNGSLFCSACKDKSVRI 202
+ ++ WN G+L + D RI
Sbjct: 222 VPSNKDVTSLDWNSEGTLLATGSYDGFARI 251
>gi|4506439 retinoblastoma binding protein 7 [Homo sapiens]
Length = 425
Score = 63.9 bits (154), Expect = 3e-10
Identities = 46/219 (21%), Positives = 96/219 (43%), Gaps = 10/219 (4%)
Query: 18 QPVKNDQCYEDIRVSRVTWDSTFCAVNPKFLAVIVEASGGGAFLVLPLS---KTGRIDKA 74
+P + +C D+R+ + + N ++ AS + ++ K G+I A
Sbjct: 159 KPDPSGECNPDLRLRGHQKEGYGLSWNSNLSGHLLSASDDHTVCLWDINAGPKEGKIVDA 218
Query: 75 YPTVCGHTGPVLDIDWCPHNDEVIASGSEDCTVMVWQIPENGLTSPLTEPVVVLEGHTKR 134
GH+ V D+ W ++ + S ++D +M+W N ++P +++ HT
Sbjct: 219 KAIFTGHSAVVEDVAWHLLHESLFGSVADDQKLMIWDTRSN----TTSKPSHLVDAHTAE 274
Query: 135 VGIIAWHPTARNVLLSAGCDNVVLIWNVGTAEELYRLDSLHPDLIYNVSWN-HNGSLFCS 193
V ++++P + +L + D V +W++ + H D I+ V W+ HN ++ S
Sbjct: 275 VNCLSFNPYSEFILATGSADKTVALWDLRNLKLKLHTFESHKDEIFQVHWSPHNETILAS 334
Query: 194 ACKDKSVRIIDPRRGTLVAEREKAHEGARPMRAIFLADG 232
+ D+ + + D + E A +G P +F+ G
Sbjct: 335 SGTDRRLNVWDLSKIGEEQSAEDAEDG--PPELLFIHGG 371
Score = 52.0 bits (123), Expect = 1e-06
Identities = 26/96 (27%), Positives = 45/96 (46%), Gaps = 9/96 (9%)
Query: 81 HTGPVLDIDWCPHNDEVIASGSEDCTVMVWQIPENGLTSPLT-------EPVVVLEGHTK 133
H + + W PHN+ ++AS D + VW + + G E + + GHT
Sbjct: 315 HKDEIFQVHWSPHNETILASSGTDRRLNVWDLSKIGEEQSAEDAEDGPPELLFIHGGHTA 374
Query: 134 RVGIIAWHPTARNVLLSAGCDNVVLIWNVGTAEELY 169
++ +W+P V+ S DN++ IW + AE +Y
Sbjct: 375 KISDFSWNPNEPWVICSVSEDNIMQIWQM--AENIY 408
Score = 48.5 bits (114), Expect = 1e-05
Identities = 44/212 (20%), Positives = 84/212 (39%), Gaps = 18/212 (8%)
Query: 80 GHTGPVLDIDWCPHNDEVIASGSEDCTVMVWQIPENGLTSPLTEPVVVLEGHTKRVGIIA 139
GH + W + + S S+D TV +W I + + + GH+ V +A
Sbjct: 174 GHQKEGYGLSWNSNLSGHLLSASDDHTVCLWDINAGPKEGKIVDAKAIFTGHSAVVEDVA 233
Query: 140 WHPTARNVLLSAGCDNVVLIWNV--GTAEELYRLDSLHPDLIYNVSWN-HNGSLFCSACK 196
WH ++ S D ++IW+ T + L H + +S+N ++ + +
Sbjct: 234 WHLLHESLFGSVADDQKLMIWDTRSNTTSKPSHLVDAHTAEVNCLSFNPYSEFILATGSA 293
Query: 197 DKSVRIIDPRRGTLVAEREKAHEGA------RPMRAIFLADGKVFTTGFSRMSERQLALW 250
DK+V + D R L ++H+ P LA S ++R+L +W
Sbjct: 294 DKTVALWDLRNLKLKLHTFESHKDEIFQVHWSPHNETILA---------SSGTDRRLNVW 344
Query: 251 DPENLEEPMALQELDSSNGALLPFYDPDTSVV 282
D + E + ++ + LL + T+ +
Sbjct: 345 DLSKIGEEQSAEDAEDGPPELLFIHGGHTAKI 376
Score = 38.5 bits (88), Expect = 0.014
Identities = 16/36 (44%), Positives = 21/36 (58%)
Query: 80 GHTGPVLDIDWCPHNDEVIASGSEDCTVMVWQIPEN 115
GHT + D W P+ VI S SED + +WQ+ EN
Sbjct: 371 GHTAKISDFSWNPNEPWVICSVSEDNIMQIWQMAEN 406
>gi|55743149 WD repeat domain 17 isoform 2 [Homo sapiens]
Length = 1298
Score = 62.8 bits (151), Expect = 7e-10
Identities = 38/132 (28%), Positives = 60/132 (45%), Gaps = 7/132 (5%)
Query: 81 HTGPVLDIDWCPHNDEVIASGSEDCTVMVWQIPENGLTSPLTEPVVVLEGHTKRVGIIAW 140
H V DW +N ++IA+G ED V V+ + + +P+ V GHT +V + W
Sbjct: 496 HPAAVFGCDWSQNNKDMIATGCEDTNVRVYYVATSS-----DQPLKVFSGHTAKVFHVKW 550
Query: 141 HPTARNVLLSAGCDNVVLIWNVGTAEELYRLDSLHPDLIYNVSWNHN-GSLFCSACKDKS 199
P +L S D V IW+ T + + + H + + WN L S D +
Sbjct: 551 SPLREGILCSGSDDGTVRIWDY-TQDACINILNGHTAPVRGLMWNTEIPYLLISGSWDYT 609
Query: 200 VRIIDPRRGTLV 211
+++ D R GT V
Sbjct: 610 IKVWDTREGTCV 621
Score = 53.9 bits (128), Expect = 3e-07
Identities = 33/124 (26%), Positives = 55/124 (44%), Gaps = 7/124 (5%)
Query: 80 GHTGPVLDIDWCPHNDEVIASGSEDCTVMVWQIPENGLTSPLTEPVVVLEGHTKRVGIIA 139
GH + D + P + ++A+ S D T+ VW I N LT+ T P G+ + ++
Sbjct: 367 GHVETIFDCKFKPDDPNLLATASFDGTIKVWDI--NTLTAVYTSP-----GNEGVIYSLS 419
Query: 140 WHPTARNVLLSAGCDNVVLIWNVGTAEELYRLDSLHPDLIYNVSWNHNGSLFCSACKDKS 199
W P N + N IWNV + + R + + I+ ++W+H S + C
Sbjct: 420 WAPGGLNCIAGGTSRNGAFIWNVQKGKIIQRFNEHGTNGIFCIAWSHKDSKRIATCSSDG 479
Query: 200 VRII 203
II
Sbjct: 480 FCII 483
Score = 52.4 bits (124), Expect = 9e-07
Identities = 33/135 (24%), Positives = 63/135 (46%), Gaps = 15/135 (11%)
Query: 72 DKAYPTVCGHTGPVLDIDWCPHNDEVIASGSEDCTVMVWQIPENGLTSPLTEPVVVLEGH 131
D+ GHT V + W P + ++ SGS+D TV +W ++ + +L GH
Sbjct: 532 DQPLKVFSGHTAKVFHVKWSPLREGILCSGSDDGTVRIWDYTQDAC-------INILNGH 584
Query: 132 TKRVGIIAWHPTARNVLLSAGCDNVVLIWNV--GT-AEELYRLDSLHPDLIYNVSWNHNG 188
T V + W+ +L+S D + +W+ GT + +Y H +Y ++ + +
Sbjct: 585 TAPVRGLMWNTEIPYLLISGSWDYTIKVWDTREGTCVDTVYD----HGADVYGLTCHPSR 640
Query: 189 SLFCSAC-KDKSVRI 202
++C +D +VR+
Sbjct: 641 PFTMASCSRDSTVRL 655
Score = 44.3 bits (103), Expect = 3e-04
Identities = 24/91 (26%), Positives = 41/91 (45%), Gaps = 9/91 (9%)
Query: 73 KAYPTVCGHTGPVLDIDWCPHNDEVIASGSEDCTVMVWQIPENGLTSPLTEPVVVLEGHT 132
K + + H + I WCPHN ++ ASGS D V++W + E + V+ T
Sbjct: 50 KLHAIMSEHKKTITAISWCPHNPDLFASGSTDNLVIIWNVAE--------QKVIAKLDST 101
Query: 133 KRV-GIIAWHPTARNVLLSAGCDNVVLIWNV 162
K + ++W A +V+ + IW +
Sbjct: 102 KGIPASLSWCWNAEDVVAFVSHRGPLFIWTI 132
Score = 39.3 bits (90), Expect = 0.008
Identities = 22/76 (28%), Positives = 37/76 (48%), Gaps = 12/76 (15%)
Query: 127 VLEGHTKRVGIIAWHPTARNVLLSAGCDNVVLIWNVGTAEELYRLDSLHPDLIYNVSW-- 184
++ H K + I+W P ++ S DN+V+IWNV + + +LDS + ++SW
Sbjct: 54 IMSEHKKTITAISWCPHNPDLFASGSTDNLVIIWNVAEQKVIAKLDST-KGIPASLSWCW 112
Query: 185 ---------NHNGSLF 191
+H G LF
Sbjct: 113 NAEDVVAFVSHRGPLF 128
>gi|31317311 WD repeat domain 17 isoform 1 [Homo sapiens]
Length = 1322
Score = 62.8 bits (151), Expect = 7e-10
Identities = 38/132 (28%), Positives = 60/132 (45%), Gaps = 7/132 (5%)
Query: 81 HTGPVLDIDWCPHNDEVIASGSEDCTVMVWQIPENGLTSPLTEPVVVLEGHTKRVGIIAW 140
H V DW +N ++IA+G ED V V+ + + +P+ V GHT +V + W
Sbjct: 520 HPAAVFGCDWSQNNKDMIATGCEDTNVRVYYVATSS-----DQPLKVFSGHTAKVFHVKW 574
Query: 141 HPTARNVLLSAGCDNVVLIWNVGTAEELYRLDSLHPDLIYNVSWNHN-GSLFCSACKDKS 199
P +L S D V IW+ T + + + H + + WN L S D +
Sbjct: 575 SPLREGILCSGSDDGTVRIWDY-TQDACINILNGHTAPVRGLMWNTEIPYLLISGSWDYT 633
Query: 200 VRIIDPRRGTLV 211
+++ D R GT V
Sbjct: 634 IKVWDTREGTCV 645
Score = 53.9 bits (128), Expect = 3e-07
Identities = 33/124 (26%), Positives = 55/124 (44%), Gaps = 7/124 (5%)
Query: 80 GHTGPVLDIDWCPHNDEVIASGSEDCTVMVWQIPENGLTSPLTEPVVVLEGHTKRVGIIA 139
GH + D + P + ++A+ S D T+ VW I N LT+ T P G+ + ++
Sbjct: 391 GHVETIFDCKFKPDDPNLLATASFDGTIKVWDI--NTLTAVYTSP-----GNEGVIYSLS 443
Query: 140 WHPTARNVLLSAGCDNVVLIWNVGTAEELYRLDSLHPDLIYNVSWNHNGSLFCSACKDKS 199
W P N + N IWNV + + R + + I+ ++W+H S + C
Sbjct: 444 WAPGGLNCIAGGTSRNGAFIWNVQKGKIIQRFNEHGTNGIFCIAWSHKDSKRIATCSSDG 503
Query: 200 VRII 203
II
Sbjct: 504 FCII 507
Score = 52.4 bits (124), Expect = 9e-07
Identities = 33/135 (24%), Positives = 63/135 (46%), Gaps = 15/135 (11%)
Query: 72 DKAYPTVCGHTGPVLDIDWCPHNDEVIASGSEDCTVMVWQIPENGLTSPLTEPVVVLEGH 131
D+ GHT V + W P + ++ SGS+D TV +W ++ + +L GH
Sbjct: 556 DQPLKVFSGHTAKVFHVKWSPLREGILCSGSDDGTVRIWDYTQDAC-------INILNGH 608
Query: 132 TKRVGIIAWHPTARNVLLSAGCDNVVLIWNV--GT-AEELYRLDSLHPDLIYNVSWNHNG 188
T V + W+ +L+S D + +W+ GT + +Y H +Y ++ + +
Sbjct: 609 TAPVRGLMWNTEIPYLLISGSWDYTIKVWDTREGTCVDTVYD----HGADVYGLTCHPSR 664
Query: 189 SLFCSAC-KDKSVRI 202
++C +D +VR+
Sbjct: 665 PFTMASCSRDSTVRL 679
Score = 44.3 bits (103), Expect = 3e-04
Identities = 24/91 (26%), Positives = 41/91 (45%), Gaps = 9/91 (9%)
Query: 73 KAYPTVCGHTGPVLDIDWCPHNDEVIASGSEDCTVMVWQIPENGLTSPLTEPVVVLEGHT 132
K + + H + I WCPHN ++ ASGS D V++W + E + V+ T
Sbjct: 74 KLHAIMSEHKKTITAISWCPHNPDLFASGSTDNLVIIWNVAE--------QKVIAKLDST 125
Query: 133 KRV-GIIAWHPTARNVLLSAGCDNVVLIWNV 162
K + ++W A +V+ + IW +
Sbjct: 126 KGIPASLSWCWNAEDVVAFVSHRGPLFIWTI 156
Score = 39.3 bits (90), Expect = 0.008
Identities = 22/76 (28%), Positives = 37/76 (48%), Gaps = 12/76 (15%)
Query: 127 VLEGHTKRVGIIAWHPTARNVLLSAGCDNVVLIWNVGTAEELYRLDSLHPDLIYNVSW-- 184
++ H K + I+W P ++ S DN+V+IWNV + + +LDS + ++SW
Sbjct: 78 IMSEHKKTITAISWCPHNPDLFASGSTDNLVIIWNVAEQKVIAKLDST-KGIPASLSWCW 136
Query: 185 ---------NHNGSLF 191
+H G LF
Sbjct: 137 NAEDVVAFVSHRGPLF 152
>gi|7657381 PRP19/PSO4 pre-mRNA processing factor 19 homolog [Homo
sapiens]
Length = 504
Score = 62.4 bits (150), Expect = 9e-10
Identities = 52/230 (22%), Positives = 96/230 (41%), Gaps = 22/230 (9%)
Query: 75 YPTVCGHTG-------PVLDIDWCPHNDEVIASGSEDCTVMVWQIPENGLTSPLTEPVVV 127
Y V H G +L +D CP + I +G D V+V+ + +
Sbjct: 207 YRQVASHVGLHSASIPGILALDLCPSDTNKILTGGADKNVVVFDKSSEQI-------LAT 259
Query: 128 LEGHTKRVGIIAWHPTARNVLLSAGCDNVVLIWNVGTAEELYRLDSLHPDLIYNVSWNHN 187
L+GHTK+V + +HP +++++ SA D + IW+V A ++ H + +S +
Sbjct: 260 LKGHTKKVTSVVFHP-SQDLVFSASPDATIRIWSVPNA-SCVQVVRAHESAVTGLSLHAT 317
Query: 188 GSLFCSACKDKSVRIIDPRRGTLVAEREKAHEGARPMRAIFLADGKVFTTGFSRMSERQL 247
G S+ D+ D + G ++ + G A F DG +F TG + Q+
Sbjct: 318 GDYLLSSSDDQYWAFSDIQTGRVLTKVTDETSGCSLTCAQFHPDGLIFGTG---TMDSQI 374
Query: 248 ALWDPENLEEPMALQELDSSNGALLPFYDPDTSVVYVCGKGDSSIRYFEI 297
+WD L+E + +G + + DSS++ +++
Sbjct: 375 KIWD---LKERTNVANFPGHSGPITSIAFSENGYYLATAADDSSVKLWDL 421
>gi|56243590 WD repeat domain 33 isoform 1 [Homo sapiens]
Length = 1336
Score = 61.6 bits (148), Expect = 2e-09
Identities = 42/156 (26%), Positives = 65/156 (41%), Gaps = 39/156 (25%)
Query: 80 GHTGPVLDIDWCPHNDEVIASGSEDC-----------------------TVMVWQIPENG 116
GH V +DW P ++ SGS+D TVM ++ NG
Sbjct: 242 GHGADVKCVDWHP-TKGLVVSGSKDSQQPIKFWDPKTGQSLATLHAHKNTVMEVKLNLNG 300
Query: 117 ---LTSP------------LTEPVVVLEGHTKRVGIIAWHPTARNVLLSAGCDNVVLIWN 161
LT+ L E + V GH K +AWHP + S G D +L W+
Sbjct: 301 NWLLTASRDHLCKLFDIRNLKEELQVFRGHKKEATAVAWHPVHEGLFASGGSDGSLLFWH 360
Query: 162 VGTAEELYRLDSLHPDLIYNVSWNHNGSLFCSACKD 197
VG +E+ ++ H +I++++W+ G + CS D
Sbjct: 361 VGVEKEVGGMEMAHEGMIWSLAWHPLGHILCSGSND 396
Score = 42.4 bits (98), Expect = 0.001
Identities = 32/128 (25%), Positives = 56/128 (43%), Gaps = 12/128 (9%)
Query: 81 HTGPVLDIDWCPHNDEVIASGSEDCTVMVWQIPENGLTSPLTEPVVVLEGHTKRVGIIAW 140
H + + + P D A+ S+D TV +W +L GH V + W
Sbjct: 201 HKEAIREASFSP-TDNKFATCSDDGTVRIWDFLR-------CHEERILRGHGADVKCVDW 252
Query: 141 HPTARNVLLSAGCDN--VVLIWNVGTAEELYRLDSLHPDLIYNVSWNHNGSLFCSACKDK 198
HPT + +++S D+ + W+ T + L L + H + + V N NG+ +A +D
Sbjct: 253 HPT-KGLVVSGSKDSQQPIKFWDPKTGQSLATLHA-HKNTVMEVKLNLNGNWLLTASRDH 310
Query: 199 SVRIIDPR 206
++ D R
Sbjct: 311 LCKLFDIR 318
Score = 33.1 bits (74), Expect = 0.59
Identities = 20/81 (24%), Positives = 36/81 (44%), Gaps = 7/81 (8%)
Query: 80 GHTGPVLDIDWCPHNDEVIASGSEDCTVMVWQIPENGLTSPLTEPVVVLEGHTKRVGIIA 139
GH + W P ++ + ASG D +++ W + G+ + + EG + +A
Sbjct: 329 GHKKEATAVAWHPVHEGLFASGGSDGSLLFWHV---GVEKEVGGMEMAHEG---MIWSLA 382
Query: 140 WHPTARNVLLSAGCDNVVLIW 160
WHP ++L S D+ W
Sbjct: 383 WHPLG-HILCSGSNDHTSKFW 402
>gi|213021190 transducin beta-like 1X isoform b [Homo sapiens]
Length = 526
Score = 60.8 bits (146), Expect = 3e-09
Identities = 51/181 (28%), Positives = 77/181 (42%), Gaps = 27/181 (14%)
Query: 68 TGRIDKAYPTVCGHTGPVLDIDWCPHNDEVIASGSEDCTVMVWQIPENGLTSPLTEPVVV 127
TG + +P H+ P LD+DW N+ AS S D + V ++ PV
Sbjct: 309 TGEAKQQFPF---HSAPALDVDW--QNNTTFASCSTDMCIHVCRLG-------CDRPVKT 356
Query: 128 LEGHTKRVGIIAWHPTARNVLLSAGCDNVVLIWNVGTAEELYRLDSLHPDLIYNVSWNHN 187
+GHT V I W P+ +L S D + IW++ ++ L + H IY + W+
Sbjct: 357 FQGHTNEVNAIKWDPSGM-LLASCSDDMTLKIWSMKQEVCIHDLQA-HNKEIYTIKWSPT 414
Query: 188 GS---------LFCSACKDKSVRIIDPRRGTLVAEREKAHEGARPMRAI-FLADGKVFTT 237
G + SA D +VR+ D RG K E P+ ++ F DGK +
Sbjct: 415 GPATSNPNSNIMLASASFDSTVRLWDIERGVCTHTLTKHQE---PVYSVAFSPDGKYLAS 471
Query: 238 G 238
G
Sbjct: 472 G 472
Score = 46.2 bits (108), Expect = 7e-05
Identities = 40/136 (29%), Positives = 55/136 (40%), Gaps = 11/136 (8%)
Query: 80 GHTGPVLDIDWCPHNDEVIASGSEDCTVMVWQIPEN---GLTSPLTEPVVVLEGH----T 132
GH V W P +D ++ASGS D T +W + EN G T + + GH
Sbjct: 179 GHESEVFICAWNPVSD-LLASGSGDSTARIWNLNENSNGGSTQLVLRHCIREGGHDVPSN 237
Query: 133 KRVGIIAWHPTARNVLLSAGCDNVVLIWNVGTAEELYRLDSLHPDLIYNVSWNHNGSLFC 192
K V + W+ T +L + D IW L H I+ + WN G+
Sbjct: 238 KDVTSLDWN-TNGTLLATGSYDGFARIWT--EDGNLASTLGQHKGPIFALKWNRKGNYIL 294
Query: 193 SACKDKSVRIIDPRRG 208
SA DK+ I D G
Sbjct: 295 SAGVDKTTIIWDAHTG 310
Score = 45.1 bits (105), Expect = 1e-04
Identities = 33/116 (28%), Positives = 53/116 (45%), Gaps = 10/116 (8%)
Query: 92 PHNDEVIASGSEDCTVMVWQIPENGLTSPLTEPVVVLEGHTKRVGIIAWHPTARNVLLSA 151
P+++ ++AS S D TV +W I T LT+ H + V +A+ P + L S
Sbjct: 421 PNSNIMLASASFDSTVRLWDIERGVCTHTLTK-------HQEPVYSVAFSPDGK-YLASG 472
Query: 152 GCDNVVLIWNVGTAEELYRLDSLHPDLIYNVSWNHNGSLFCSACKDKSVRIIDPRR 207
D V IWN + ++ I+ V WN G ++ D SV ++D R+
Sbjct: 473 SFDKCVHIWNTQSGNLVHSYRGTGG--IFEVCWNARGDKVGASASDGSVCVLDLRK 526
Score = 40.0 bits (92), Expect = 0.005
Identities = 34/127 (26%), Positives = 53/127 (41%), Gaps = 16/127 (12%)
Query: 80 GHTGP----VLDIDWCPHNDEVIASGSEDCTVMVWQIPENGLTSPLTEPVVVLEGHTKRV 135
GH P V +DW N ++A+GS D +W + L S L + H +
Sbjct: 231 GHDVPSNKDVTSLDWNT-NGTLLATGSYDGFARIWT-EDGNLASTLGQ-------HKGPI 281
Query: 136 GIIAWHPTARNVLLSAGCDNVVLIWNVGTAEELYRLDSLHPDLIYNVSWNHNGSLFCSAC 195
+ W+ N +LSAG D +IW+ T E + H +V W +N + F S
Sbjct: 282 FALKWNRKG-NYILSAGVDKTTIIWDAHTGEAKQQF-PFHSAPALDVDWQNN-TTFASCS 338
Query: 196 KDKSVRI 202
D + +
Sbjct: 339 TDMCIHV 345
Score = 35.4 bits (80), Expect = 0.12
Identities = 26/89 (29%), Positives = 40/89 (44%), Gaps = 14/89 (15%)
Query: 127 VLEGHTKRVGIIAWHPTARNVLLSAGCDNVVLIWNV------GTAEELYR-------LDS 173
VL GH V I AW+P + ++L S D+ IWN+ G+ + + R D
Sbjct: 176 VLRGHESEVFICAWNPVS-DLLASGSGDSTARIWNLNENSNGGSTQLVLRHCIREGGHDV 234
Query: 174 LHPDLIYNVSWNHNGSLFCSACKDKSVRI 202
+ ++ WN NG+L + D RI
Sbjct: 235 PSNKDVTSLDWNTNGTLLATGSYDGFARI 263
>gi|213021188 transducin beta-like 1X isoform b [Homo sapiens]
Length = 526
Score = 60.8 bits (146), Expect = 3e-09
Identities = 51/181 (28%), Positives = 77/181 (42%), Gaps = 27/181 (14%)
Query: 68 TGRIDKAYPTVCGHTGPVLDIDWCPHNDEVIASGSEDCTVMVWQIPENGLTSPLTEPVVV 127
TG + +P H+ P LD+DW N+ AS S D + V ++ PV
Sbjct: 309 TGEAKQQFPF---HSAPALDVDW--QNNTTFASCSTDMCIHVCRLG-------CDRPVKT 356
Query: 128 LEGHTKRVGIIAWHPTARNVLLSAGCDNVVLIWNVGTAEELYRLDSLHPDLIYNVSWNHN 187
+GHT V I W P+ +L S D + IW++ ++ L + H IY + W+
Sbjct: 357 FQGHTNEVNAIKWDPSGM-LLASCSDDMTLKIWSMKQEVCIHDLQA-HNKEIYTIKWSPT 414
Query: 188 GS---------LFCSACKDKSVRIIDPRRGTLVAEREKAHEGARPMRAI-FLADGKVFTT 237
G + SA D +VR+ D RG K E P+ ++ F DGK +
Sbjct: 415 GPATSNPNSNIMLASASFDSTVRLWDIERGVCTHTLTKHQE---PVYSVAFSPDGKYLAS 471
Query: 238 G 238
G
Sbjct: 472 G 472
Score = 46.2 bits (108), Expect = 7e-05
Identities = 40/136 (29%), Positives = 55/136 (40%), Gaps = 11/136 (8%)
Query: 80 GHTGPVLDIDWCPHNDEVIASGSEDCTVMVWQIPEN---GLTSPLTEPVVVLEGH----T 132
GH V W P +D ++ASGS D T +W + EN G T + + GH
Sbjct: 179 GHESEVFICAWNPVSD-LLASGSGDSTARIWNLNENSNGGSTQLVLRHCIREGGHDVPSN 237
Query: 133 KRVGIIAWHPTARNVLLSAGCDNVVLIWNVGTAEELYRLDSLHPDLIYNVSWNHNGSLFC 192
K V + W+ T +L + D IW L H I+ + WN G+
Sbjct: 238 KDVTSLDWN-TNGTLLATGSYDGFARIWT--EDGNLASTLGQHKGPIFALKWNRKGNYIL 294
Query: 193 SACKDKSVRIIDPRRG 208
SA DK+ I D G
Sbjct: 295 SAGVDKTTIIWDAHTG 310
Score = 45.1 bits (105), Expect = 1e-04
Identities = 33/116 (28%), Positives = 53/116 (45%), Gaps = 10/116 (8%)
Query: 92 PHNDEVIASGSEDCTVMVWQIPENGLTSPLTEPVVVLEGHTKRVGIIAWHPTARNVLLSA 151
P+++ ++AS S D TV +W I T LT+ H + V +A+ P + L S
Sbjct: 421 PNSNIMLASASFDSTVRLWDIERGVCTHTLTK-------HQEPVYSVAFSPDGK-YLASG 472
Query: 152 GCDNVVLIWNVGTAEELYRLDSLHPDLIYNVSWNHNGSLFCSACKDKSVRIIDPRR 207
D V IWN + ++ I+ V WN G ++ D SV ++D R+
Sbjct: 473 SFDKCVHIWNTQSGNLVHSYRGTGG--IFEVCWNARGDKVGASASDGSVCVLDLRK 526
Score = 40.0 bits (92), Expect = 0.005
Identities = 34/127 (26%), Positives = 53/127 (41%), Gaps = 16/127 (12%)
Query: 80 GHTGP----VLDIDWCPHNDEVIASGSEDCTVMVWQIPENGLTSPLTEPVVVLEGHTKRV 135
GH P V +DW N ++A+GS D +W + L S L + H +
Sbjct: 231 GHDVPSNKDVTSLDWNT-NGTLLATGSYDGFARIWT-EDGNLASTLGQ-------HKGPI 281
Query: 136 GIIAWHPTARNVLLSAGCDNVVLIWNVGTAEELYRLDSLHPDLIYNVSWNHNGSLFCSAC 195
+ W+ N +LSAG D +IW+ T E + H +V W +N + F S
Sbjct: 282 FALKWNRKG-NYILSAGVDKTTIIWDAHTGEAKQQF-PFHSAPALDVDWQNN-TTFASCS 338
Query: 196 KDKSVRI 202
D + +
Sbjct: 339 TDMCIHV 345
Score = 35.4 bits (80), Expect = 0.12
Identities = 26/89 (29%), Positives = 40/89 (44%), Gaps = 14/89 (15%)
Query: 127 VLEGHTKRVGIIAWHPTARNVLLSAGCDNVVLIWNV------GTAEELYR-------LDS 173
VL GH V I AW+P + ++L S D+ IWN+ G+ + + R D
Sbjct: 176 VLRGHESEVFICAWNPVS-DLLASGSGDSTARIWNLNENSNGGSTQLVLRHCIREGGHDV 234
Query: 174 LHPDLIYNVSWNHNGSLFCSACKDKSVRI 202
+ ++ WN NG+L + D RI
Sbjct: 235 PSNKDVTSLDWNTNGTLLATGSYDGFARI 263
>gi|213021186 transducin beta-like 1X isoform a [Homo sapiens]
Length = 577
Score = 60.8 bits (146), Expect = 3e-09
Identities = 51/181 (28%), Positives = 77/181 (42%), Gaps = 27/181 (14%)
Query: 68 TGRIDKAYPTVCGHTGPVLDIDWCPHNDEVIASGSEDCTVMVWQIPENGLTSPLTEPVVV 127
TG + +P H+ P LD+DW N+ AS S D + V ++ PV
Sbjct: 360 TGEAKQQFPF---HSAPALDVDW--QNNTTFASCSTDMCIHVCRLG-------CDRPVKT 407
Query: 128 LEGHTKRVGIIAWHPTARNVLLSAGCDNVVLIWNVGTAEELYRLDSLHPDLIYNVSWNHN 187
+GHT V I W P+ +L S D + IW++ ++ L + H IY + W+
Sbjct: 408 FQGHTNEVNAIKWDPSGM-LLASCSDDMTLKIWSMKQEVCIHDLQA-HNKEIYTIKWSPT 465
Query: 188 GS---------LFCSACKDKSVRIIDPRRGTLVAEREKAHEGARPMRAI-FLADGKVFTT 237
G + SA D +VR+ D RG K E P+ ++ F DGK +
Sbjct: 466 GPATSNPNSNIMLASASFDSTVRLWDIERGVCTHTLTKHQE---PVYSVAFSPDGKYLAS 522
Query: 238 G 238
G
Sbjct: 523 G 523
Score = 46.2 bits (108), Expect = 7e-05
Identities = 40/136 (29%), Positives = 55/136 (40%), Gaps = 11/136 (8%)
Query: 80 GHTGPVLDIDWCPHNDEVIASGSEDCTVMVWQIPEN---GLTSPLTEPVVVLEGH----T 132
GH V W P +D ++ASGS D T +W + EN G T + + GH
Sbjct: 230 GHESEVFICAWNPVSD-LLASGSGDSTARIWNLNENSNGGSTQLVLRHCIREGGHDVPSN 288
Query: 133 KRVGIIAWHPTARNVLLSAGCDNVVLIWNVGTAEELYRLDSLHPDLIYNVSWNHNGSLFC 192
K V + W+ T +L + D IW L H I+ + WN G+
Sbjct: 289 KDVTSLDWN-TNGTLLATGSYDGFARIWT--EDGNLASTLGQHKGPIFALKWNRKGNYIL 345
Query: 193 SACKDKSVRIIDPRRG 208
SA DK+ I D G
Sbjct: 346 SAGVDKTTIIWDAHTG 361
Score = 45.1 bits (105), Expect = 1e-04
Identities = 33/116 (28%), Positives = 53/116 (45%), Gaps = 10/116 (8%)
Query: 92 PHNDEVIASGSEDCTVMVWQIPENGLTSPLTEPVVVLEGHTKRVGIIAWHPTARNVLLSA 151
P+++ ++AS S D TV +W I T LT+ H + V +A+ P + L S
Sbjct: 472 PNSNIMLASASFDSTVRLWDIERGVCTHTLTK-------HQEPVYSVAFSPDGK-YLASG 523
Query: 152 GCDNVVLIWNVGTAEELYRLDSLHPDLIYNVSWNHNGSLFCSACKDKSVRIIDPRR 207
D V IWN + ++ I+ V WN G ++ D SV ++D R+
Sbjct: 524 SFDKCVHIWNTQSGNLVHSYRGTGG--IFEVCWNARGDKVGASASDGSVCVLDLRK 577
Score = 40.0 bits (92), Expect = 0.005
Identities = 34/127 (26%), Positives = 53/127 (41%), Gaps = 16/127 (12%)
Query: 80 GHTGP----VLDIDWCPHNDEVIASGSEDCTVMVWQIPENGLTSPLTEPVVVLEGHTKRV 135
GH P V +DW N ++A+GS D +W + L S L + H +
Sbjct: 282 GHDVPSNKDVTSLDWNT-NGTLLATGSYDGFARIWT-EDGNLASTLGQ-------HKGPI 332
Query: 136 GIIAWHPTARNVLLSAGCDNVVLIWNVGTAEELYRLDSLHPDLIYNVSWNHNGSLFCSAC 195
+ W+ N +LSAG D +IW+ T E + H +V W +N + F S
Sbjct: 333 FALKWNRKG-NYILSAGVDKTTIIWDAHTGEAKQQF-PFHSAPALDVDWQNN-TTFASCS 389
Query: 196 KDKSVRI 202
D + +
Sbjct: 390 TDMCIHV 396
Score = 35.4 bits (80), Expect = 0.12
Identities = 26/89 (29%), Positives = 40/89 (44%), Gaps = 14/89 (15%)
Query: 127 VLEGHTKRVGIIAWHPTARNVLLSAGCDNVVLIWNV------GTAEELYR-------LDS 173
VL GH V I AW+P + ++L S D+ IWN+ G+ + + R D
Sbjct: 227 VLRGHESEVFICAWNPVS-DLLASGSGDSTARIWNLNENSNGGSTQLVLRHCIREGGHDV 285
Query: 174 LHPDLIYNVSWNHNGSLFCSACKDKSVRI 202
+ ++ WN NG+L + D RI
Sbjct: 286 PSNKDVTSLDWNTNGTLLATGSYDGFARI 314
>gi|5032159 transducin beta-like 1X isoform a [Homo sapiens]
Length = 577
Score = 60.8 bits (146), Expect = 3e-09
Identities = 51/181 (28%), Positives = 77/181 (42%), Gaps = 27/181 (14%)
Query: 68 TGRIDKAYPTVCGHTGPVLDIDWCPHNDEVIASGSEDCTVMVWQIPENGLTSPLTEPVVV 127
TG + +P H+ P LD+DW N+ AS S D + V ++ PV
Sbjct: 360 TGEAKQQFPF---HSAPALDVDW--QNNTTFASCSTDMCIHVCRLG-------CDRPVKT 407
Query: 128 LEGHTKRVGIIAWHPTARNVLLSAGCDNVVLIWNVGTAEELYRLDSLHPDLIYNVSWNHN 187
+GHT V I W P+ +L S D + IW++ ++ L + H IY + W+
Sbjct: 408 FQGHTNEVNAIKWDPSGM-LLASCSDDMTLKIWSMKQEVCIHDLQA-HNKEIYTIKWSPT 465
Query: 188 GS---------LFCSACKDKSVRIIDPRRGTLVAEREKAHEGARPMRAI-FLADGKVFTT 237
G + SA D +VR+ D RG K E P+ ++ F DGK +
Sbjct: 466 GPATSNPNSNIMLASASFDSTVRLWDIERGVCTHTLTKHQE---PVYSVAFSPDGKYLAS 522
Query: 238 G 238
G
Sbjct: 523 G 523
Score = 46.2 bits (108), Expect = 7e-05
Identities = 40/136 (29%), Positives = 55/136 (40%), Gaps = 11/136 (8%)
Query: 80 GHTGPVLDIDWCPHNDEVIASGSEDCTVMVWQIPEN---GLTSPLTEPVVVLEGH----T 132
GH V W P +D ++ASGS D T +W + EN G T + + GH
Sbjct: 230 GHESEVFICAWNPVSD-LLASGSGDSTARIWNLNENSNGGSTQLVLRHCIREGGHDVPSN 288
Query: 133 KRVGIIAWHPTARNVLLSAGCDNVVLIWNVGTAEELYRLDSLHPDLIYNVSWNHNGSLFC 192
K V + W+ T +L + D IW L H I+ + WN G+
Sbjct: 289 KDVTSLDWN-TNGTLLATGSYDGFARIWT--EDGNLASTLGQHKGPIFALKWNRKGNYIL 345
Query: 193 SACKDKSVRIIDPRRG 208
SA DK+ I D G
Sbjct: 346 SAGVDKTTIIWDAHTG 361
Score = 45.1 bits (105), Expect = 1e-04
Identities = 33/116 (28%), Positives = 53/116 (45%), Gaps = 10/116 (8%)
Query: 92 PHNDEVIASGSEDCTVMVWQIPENGLTSPLTEPVVVLEGHTKRVGIIAWHPTARNVLLSA 151
P+++ ++AS S D TV +W I T LT+ H + V +A+ P + L S
Sbjct: 472 PNSNIMLASASFDSTVRLWDIERGVCTHTLTK-------HQEPVYSVAFSPDGK-YLASG 523
Query: 152 GCDNVVLIWNVGTAEELYRLDSLHPDLIYNVSWNHNGSLFCSACKDKSVRIIDPRR 207
D V IWN + ++ I+ V WN G ++ D SV ++D R+
Sbjct: 524 SFDKCVHIWNTQSGNLVHSYRGTGG--IFEVCWNARGDKVGASASDGSVCVLDLRK 577
Score = 40.0 bits (92), Expect = 0.005
Identities = 34/127 (26%), Positives = 53/127 (41%), Gaps = 16/127 (12%)
Query: 80 GHTGP----VLDIDWCPHNDEVIASGSEDCTVMVWQIPENGLTSPLTEPVVVLEGHTKRV 135
GH P V +DW N ++A+GS D +W + L S L + H +
Sbjct: 282 GHDVPSNKDVTSLDWNT-NGTLLATGSYDGFARIWT-EDGNLASTLGQ-------HKGPI 332
Query: 136 GIIAWHPTARNVLLSAGCDNVVLIWNVGTAEELYRLDSLHPDLIYNVSWNHNGSLFCSAC 195
+ W+ N +LSAG D +IW+ T E + H +V W +N + F S
Sbjct: 333 FALKWNRKG-NYILSAGVDKTTIIWDAHTGEAKQQF-PFHSAPALDVDWQNN-TTFASCS 389
Query: 196 KDKSVRI 202
D + +
Sbjct: 390 TDMCIHV 396
Score = 35.4 bits (80), Expect = 0.12
Identities = 26/89 (29%), Positives = 40/89 (44%), Gaps = 14/89 (15%)
Query: 127 VLEGHTKRVGIIAWHPTARNVLLSAGCDNVVLIWNV------GTAEELYR-------LDS 173
VL GH V I AW+P + ++L S D+ IWN+ G+ + + R D
Sbjct: 227 VLRGHESEVFICAWNPVS-DLLASGSGDSTARIWNLNENSNGGSTQLVLRHCIREGGHDV 285
Query: 174 LHPDLIYNVSWNHNGSLFCSACKDKSVRI 202
+ ++ WN NG+L + D RI
Sbjct: 286 PSNKDVTSLDWNTNGTLLATGSYDGFARI 314
>gi|169403944 WD repeat domain 26 isoform b [Homo sapiens]
Length = 498
Score = 60.8 bits (146), Expect = 3e-09
Identities = 34/96 (35%), Positives = 55/96 (57%), Gaps = 6/96 (6%)
Query: 98 IASGSEDCTVMVWQIPENGLTSPLTEPVVVLEGHTKRVGIIAWHPTARNVLLSAGCDNV- 156
+A+GS+D TV++WQ+ + + L + + LEGH V IAW P N L++ G D+
Sbjct: 207 LATGSKDTTVIIWQVDPD---THLLKLLKTLEGHAYGVSYIAWSPDD-NYLVACGPDDCS 262
Query: 157 -VLIWNVGTAEELYRLDSLHPDLIYNVSWNHNGSLF 191
+ +WNV T E ++ H D + +V+WN +G F
Sbjct: 263 ELWLWNVQTGELRTKMSQSHEDSLTSVAWNPDGKRF 298
Score = 51.6 bits (122), Expect = 2e-06
Identities = 27/68 (39%), Positives = 38/68 (55%), Gaps = 7/68 (10%)
Query: 93 HNDEVIASGSEDCTVMVWQIPENGLTSPLTEPVVVLEGHTKRVGIIAWHPTARNVLLSAG 152
HN++ IASGSED V +W S L P+ L GHT+ V ++W+P +++ SA
Sbjct: 418 HNEDFIASGSEDHKVYIWH-----KRSEL--PIAELTGHTRTVNCVSWNPQIPSMMASAS 470
Query: 153 CDNVVLIW 160
D V IW
Sbjct: 471 DDGTVRIW 478
Score = 35.0 bits (79), Expect = 0.15
Identities = 18/74 (24%), Positives = 36/74 (48%), Gaps = 7/74 (9%)
Query: 73 KAYPTVCGHTGPVLDIDWCPHNDEVIASGSEDCT-VMVWQIPENGLTSPLTEPVVVLEGH 131
K T+ GH V I W P ++ ++A G +DC+ + +W + L + ++ + H
Sbjct: 229 KLLKTLEGHAYGVSYIAWSPDDNYLVACGPDDCSELWLWNVQTGELRTKMS------QSH 282
Query: 132 TKRVGIIAWHPTAR 145
+ +AW+P +
Sbjct: 283 EDSLTSVAWNPDGK 296
Score = 31.6 bits (70), Expect = 1.7
Identities = 26/85 (30%), Positives = 35/85 (41%), Gaps = 7/85 (8%)
Query: 26 YEDIRVSRVTWDSTFCAVNPKFLAVIVEASGGGAFLVLPLSKTGRIDKAYPTVCGHTGPV 85
Y+ + T S F N F+A SG V K + A T GHT V
Sbjct: 401 YQGVTQGFYTIHSCFGGHNEDFIA-----SGSEDHKVYIWHKRSELPIAELT--GHTRTV 453
Query: 86 LDIDWCPHNDEVIASGSEDCTVMVW 110
+ W P ++AS S+D TV +W
Sbjct: 454 NCVSWNPQIPSMMASASDDGTVRIW 478
>gi|55743153 WD repeat domain 26 isoform a [Homo sapiens]
Length = 514
Score = 60.8 bits (146), Expect = 3e-09
Identities = 34/96 (35%), Positives = 55/96 (57%), Gaps = 6/96 (6%)
Query: 98 IASGSEDCTVMVWQIPENGLTSPLTEPVVVLEGHTKRVGIIAWHPTARNVLLSAGCDNV- 156
+A+GS+D TV++WQ+ + + L + + LEGH V IAW P N L++ G D+
Sbjct: 223 LATGSKDTTVIIWQVDPD---THLLKLLKTLEGHAYGVSYIAWSPDD-NYLVACGPDDCS 278
Query: 157 -VLIWNVGTAEELYRLDSLHPDLIYNVSWNHNGSLF 191
+ +WNV T E ++ H D + +V+WN +G F
Sbjct: 279 ELWLWNVQTGELRTKMSQSHEDSLTSVAWNPDGKRF 314
Score = 51.6 bits (122), Expect = 2e-06
Identities = 27/68 (39%), Positives = 38/68 (55%), Gaps = 7/68 (10%)
Query: 93 HNDEVIASGSEDCTVMVWQIPENGLTSPLTEPVVVLEGHTKRVGIIAWHPTARNVLLSAG 152
HN++ IASGSED V +W S L P+ L GHT+ V ++W+P +++ SA
Sbjct: 434 HNEDFIASGSEDHKVYIWH-----KRSEL--PIAELTGHTRTVNCVSWNPQIPSMMASAS 486
Query: 153 CDNVVLIW 160
D V IW
Sbjct: 487 DDGTVRIW 494
Score = 35.0 bits (79), Expect = 0.15
Identities = 18/74 (24%), Positives = 36/74 (48%), Gaps = 7/74 (9%)
Query: 73 KAYPTVCGHTGPVLDIDWCPHNDEVIASGSEDCT-VMVWQIPENGLTSPLTEPVVVLEGH 131
K T+ GH V I W P ++ ++A G +DC+ + +W + L + ++ + H
Sbjct: 245 KLLKTLEGHAYGVSYIAWSPDDNYLVACGPDDCSELWLWNVQTGELRTKMS------QSH 298
Query: 132 TKRVGIIAWHPTAR 145
+ +AW+P +
Sbjct: 299 EDSLTSVAWNPDGK 312
Score = 31.6 bits (70), Expect = 1.7
Identities = 26/85 (30%), Positives = 35/85 (41%), Gaps = 7/85 (8%)
Query: 26 YEDIRVSRVTWDSTFCAVNPKFLAVIVEASGGGAFLVLPLSKTGRIDKAYPTVCGHTGPV 85
Y+ + T S F N F+A SG V K + A T GHT V
Sbjct: 417 YQGVTQGFYTIHSCFGGHNEDFIA-----SGSEDHKVYIWHKRSELPIAELT--GHTRTV 469
Query: 86 LDIDWCPHNDEVIASGSEDCTVMVW 110
+ W P ++AS S+D TV +W
Sbjct: 470 NCVSWNPQIPSMMASASDDGTVRIW 494
>gi|4505731 peroxisomal biogenesis factor 7 [Homo sapiens]
Length = 323
Score = 60.5 bits (145), Expect = 3e-09
Identities = 33/133 (24%), Positives = 60/133 (45%), Gaps = 7/133 (5%)
Query: 81 HTGPVLDIDWCPHNDEVIASGSEDCTVMVWQIPENGLTSPLTEPVVVLEGHTKRVGIIAW 140
H +L DWC +N+ ++ +G+ DC++ W + + +PV L GHT + + +
Sbjct: 197 HQAEILSCDWCKYNENLLVTGAVDCSLRGWDLRN------VRQPVFELLGHTYAIRRVKF 250
Query: 141 HPTARNVLLSAGCDNVVLIWNVGTAEELYRLDSLHPDLIYNVSWNHNGSLFCSACK-DKS 199
P +VL S D V WN + L H + + ++ + C D++
Sbjct: 251 SPFHASVLASCSYDFTVRFWNFSKPDSLLETVEHHTEFTCGLDFSLQSPTQVADCSWDET 310
Query: 200 VRIIDPRRGTLVA 212
++I DP T+ A
Sbjct: 311 IKIYDPACLTIPA 323
Score = 51.2 bits (121), Expect = 2e-06
Identities = 38/153 (24%), Positives = 71/153 (46%), Gaps = 14/153 (9%)
Query: 55 SGGGAFLVLPLSKTG-RIDKAYPTVCGHTGPVLDIDWCPHNDEVIASGSEDCTVMVWQIP 113
+G G L+L + G R+ +++ G + D+ W +N+ V+ + S D ++ +W
Sbjct: 43 AGCGTLLILDPDEAGLRLFRSFDWNDG----LFDVTWSENNEHVLITCSGDGSLQLWD-- 96
Query: 114 ENGLTSPLTEPVVVLEGHTKRVGIIAWHPT-ARNVLLSAGCDNVVLIWNVGTAEELYRLD 172
T+ P+ V + H + V + W T +++S D V +W+ + L
Sbjct: 97 ----TAKAAGPLQVYKEHAQEVYSVDWSQTRGEQLVVSGSWDQTVKLWDPTVGKSLCTFR 152
Query: 173 SLHPDLIYNVSWN-HNGSLFCSACKDKSVRIID 204
H +IY+ W+ H F SA D+++RI D
Sbjct: 153 G-HESIIYSTIWSPHIPGCFASASGDQTLRIWD 184
Score = 42.7 bits (99), Expect = 7e-04
Identities = 40/159 (25%), Positives = 64/159 (40%), Gaps = 13/159 (8%)
Query: 50 VIVEASGGGAFLVLPLSKTGRIDKAYPTVCGHTGPVLDIDWCP-HNDEVIASGSEDCTVM 108
V++ SG G+ + +K + Y H V +DW ++++ SGS D TV
Sbjct: 82 VLITCSGDGSLQLWDTAKAAGPLQVYKE---HAQEVYSVDWSQTRGEQLVVSGSWDQTVK 138
Query: 109 VWQIPENGLTSPLTEPVVVLEGHTKRVGIIAWHPTARNVLLSAGCDNVVLIWNVGTAEEL 168
+W P G + + GH + W P SA D + IW+V A
Sbjct: 139 LWD-PTVG------KSLCTFRGHESIIYSTIWSPHIPGCFASASGDQTLRIWDVKAAGVR 191
Query: 169 YRLDSLHPDLIYNVSW-NHNGSLFCSACKDKSVRIIDPR 206
+ + H I + W +N +L + D S+R D R
Sbjct: 192 IVIPA-HQAEILSCDWCKYNENLLVTGAVDCSLRGWDLR 229
Score = 33.1 bits (74), Expect = 0.59
Identities = 17/73 (23%), Positives = 33/73 (45%), Gaps = 2/73 (2%)
Query: 138 IAWHPTARNVLLSAGCDNVVLIWNVGTAEELYRLDSLHPDLIYNVSWN--HNGSLFCSAC 195
+ W +VL++ D + +W+ A ++ H +Y+V W+ L S
Sbjct: 73 VTWSENNEHVLITCSGDGSLQLWDTAKAAGPLQVYKEHAQEVYSVDWSQTRGEQLVVSGS 132
Query: 196 KDKSVRIIDPRRG 208
D++V++ DP G
Sbjct: 133 WDQTVKLWDPTVG 145
>gi|5902034 periodic tryptophan protein 1 [Homo sapiens]
Length = 501
Score = 59.7 bits (143), Expect = 6e-09
Identities = 53/221 (23%), Positives = 92/221 (41%), Gaps = 15/221 (6%)
Query: 80 GHTGPVLDIDWCPHNDEVIASGSEDCTVMVWQIPENGLTSPLTEPVVVLEGHTKRVGIIA 139
GHT VLD+ W V+AS S D TV++W + L +P L HT +V +
Sbjct: 254 GHTDAVLDLSWNKLIRNVLASASADNTVILWDM-------SLGKPAASLAVHTDKVQTLQ 306
Query: 140 WHPTARNVLLSAGCDNVVLIWNVGTAEELYRLDSLHPDLIYNVSWNH-NGSLFCSACKDK 198
+HP L+S D V +++ + +E +R+ I V+WNH + F ++ D
Sbjct: 307 FHPFEAQTLISGSYDKSVALYDCRSPDESHRMWRFSGQ-IERVTWNHFSPCHFLASTDDG 365
Query: 199 SVRIIDPRRGTLVAEREKAHEGARPMRAIFLADGKVFTTGFSRMSERQLALWDPENLEEP 258
V +D R + ++ + G + T +++ + +WD + P
Sbjct: 366 FVYNLDARSDKPIFTLNAHNDEISGLDLSSQIKGCLVTAS----ADKYVKIWDILG-DRP 420
Query: 259 MALQELDSSNGALL-PFYDPDTSVVYVCGKGDSSIRYFEIT 298
+ D G L PD +Y G +R ++I+
Sbjct: 421 SLVHSRDMKMGVLFCSSCCPDLPFIYAFGGQKEGLRVWDIS 461
Score = 46.2 bits (108), Expect = 7e-05
Identities = 26/79 (32%), Positives = 41/79 (51%), Gaps = 2/79 (2%)
Query: 129 EGHTKRVGIIAWHPTARNVLLSAGCDNVVLIWNVGTAEELYRLDSLHPDLIYNVSWN-HN 187
EGHT V ++W+ RNVL SA DN V++W++ + L ++H D + + ++
Sbjct: 253 EGHTDAVLDLSWNKLIRNVLASASADNTVILWDMSLGKPAASL-AVHTDKVQTLQFHPFE 311
Query: 188 GSLFCSACKDKSVRIIDPR 206
S DKSV + D R
Sbjct: 312 AQTLISGSYDKSVALYDCR 330
>gi|19913367 transducin beta-like 1Y [Homo sapiens]
Length = 522
Score = 58.5 bits (140), Expect = 1e-08
Identities = 42/148 (28%), Positives = 70/148 (47%), Gaps = 17/148 (11%)
Query: 72 DKAYPTVCGHTGPVLDIDWCPHNDEVIASGSEDCTVMVWQIPENGLTSPLTEPVVVLEGH 131
D T GHT V I W P + ++AS S+D T+ +W + ++ L + H
Sbjct: 349 DHPVKTFQGHTNEVNAIKWDP-SGMLLASCSDDMTLKIWSMKQDACVHDL-------QAH 400
Query: 132 TKRVGIIAWHPT--------ARNVLLSAGCDNVVLIWNVGTAEELYRLDSLHPDLIYNVS 183
+K + I W PT + +L SA D+ V +W+V + L H + +Y+V+
Sbjct: 401 SKEIYTIKWSPTGPATSNPNSSIMLASASFDSTVRLWDVEQGVCTHTLMK-HQEPVYSVA 459
Query: 184 WNHNGSLFCSACKDKSVRIIDPRRGTLV 211
++ +G S DK V I + + G+LV
Sbjct: 460 FSPDGKYLASGSFDKYVHIWNTQSGSLV 487
Score = 44.7 bits (104), Expect = 2e-04
Identities = 41/138 (29%), Positives = 55/138 (39%), Gaps = 15/138 (10%)
Query: 80 GHTGPVLDIDWCPHNDEVIASGSEDCTVMVWQIPEN---GLTSPLTEPVVVLEGH----T 132
GH V W P +D ++ASGS D T +W + EN G T + + GH
Sbjct: 177 GHESEVFICAWNPVSD-LLASGSGDSTARIWNLNENSNGGSTQLVLRHCIREGGHDVPSN 235
Query: 133 KRVGIIAWHPTARNVLLSAGCDNVVLIW--NVGTAEELYRLDSLHPDLIYNVSWNHNGSL 190
K V + W+ +L D IW N A L H I+ + WN G+
Sbjct: 236 KDVTSLDWNSDG-TLLAMGSYDGFARIWTENGNLASTL----GQHKGPIFALKWNKKGNY 290
Query: 191 FCSACKDKSVRIIDPRRG 208
SA DK+ I D G
Sbjct: 291 VLSAGVDKTTIIWDAHTG 308
Score = 42.4 bits (98), Expect = 0.001
Identities = 33/132 (25%), Positives = 55/132 (41%), Gaps = 18/132 (13%)
Query: 81 HTGPVLDIDWCP--------HNDEVIASGSEDCTVMVWQIPENGLTSPLTEPVVVLEGHT 132
H+ + I W P ++ ++AS S D TV +W + + T L + H
Sbjct: 400 HSKEIYTIKWSPTGPATSNPNSSIMLASASFDSTVRLWDVEQGVCTHTLMK-------HQ 452
Query: 133 KRVGIIAWHPTARNVLLSAGCDNVVLIWNVGTAEELYRLDSLHPDLIYNVSWNHNGSLFC 192
+ V +A+ P + L S D V IWN + ++ I+ V WN G
Sbjct: 453 EPVYSVAFSPDGK-YLASGSFDKYVHIWNTQSGSLVHSYQGTGG--IFEVCWNARGDKVG 509
Query: 193 SACKDKSVRIID 204
++ D SV ++D
Sbjct: 510 ASASDGSVCVLD 521
Score = 38.1 bits (87), Expect = 0.018
Identities = 36/128 (28%), Positives = 53/128 (41%), Gaps = 18/128 (14%)
Query: 80 GHTGP----VLDIDWCPHNDEVIASGSEDCTVMVWQIPENG-LTSPLTEPVVVLEGHTKR 134
GH P V +DW + ++A GS D +W ENG L S L + H
Sbjct: 229 GHDVPSNKDVTSLDW-NSDGTLLAMGSYDGFARIWT--ENGNLASTLGQ-------HKGP 278
Query: 135 VGIIAWHPTARNVLLSAGCDNVVLIWNVGTAEELYRLDSLHPDLIYNVSWNHNGSLFCSA 194
+ + W+ N +LSAG D +IW+ T E + H +V W +N F S
Sbjct: 279 IFALKWNKKG-NYVLSAGVDKTTIIWDAHTGEAKQQF-PFHSAPALDVDWQNN-MTFASC 335
Query: 195 CKDKSVRI 202
D + +
Sbjct: 336 STDMCIHV 343
Score = 33.5 bits (75), Expect = 0.45
Identities = 29/105 (27%), Positives = 44/105 (41%), Gaps = 22/105 (20%)
Query: 111 QIPENGLTSPLTEPVVVLEGHTKRVGIIAWHPTARNVLLSAGCDNVVLIWNV------GT 164
+IP N T VL GH V I AW+P + ++L S D+ IWN+ G+
Sbjct: 166 EIPPNKAT--------VLRGHESEVFICAWNPVS-DLLASGSGDSTARIWNLNENSNGGS 216
Query: 165 AEELYR-------LDSLHPDLIYNVSWNHNGSLFCSACKDKSVRI 202
+ + R D + ++ WN +G+L D RI
Sbjct: 217 TQLVLRHCIREGGHDVPSNKDVTSLDWNSDGTLLAMGSYDGFARI 261
>gi|19913365 transducin beta-like 1Y [Homo sapiens]
Length = 522
Score = 58.5 bits (140), Expect = 1e-08
Identities = 42/148 (28%), Positives = 70/148 (47%), Gaps = 17/148 (11%)
Query: 72 DKAYPTVCGHTGPVLDIDWCPHNDEVIASGSEDCTVMVWQIPENGLTSPLTEPVVVLEGH 131
D T GHT V I W P + ++AS S+D T+ +W + ++ L + H
Sbjct: 349 DHPVKTFQGHTNEVNAIKWDP-SGMLLASCSDDMTLKIWSMKQDACVHDL-------QAH 400
Query: 132 TKRVGIIAWHPT--------ARNVLLSAGCDNVVLIWNVGTAEELYRLDSLHPDLIYNVS 183
+K + I W PT + +L SA D+ V +W+V + L H + +Y+V+
Sbjct: 401 SKEIYTIKWSPTGPATSNPNSSIMLASASFDSTVRLWDVEQGVCTHTLMK-HQEPVYSVA 459
Query: 184 WNHNGSLFCSACKDKSVRIIDPRRGTLV 211
++ +G S DK V I + + G+LV
Sbjct: 460 FSPDGKYLASGSFDKYVHIWNTQSGSLV 487
Score = 44.7 bits (104), Expect = 2e-04
Identities = 41/138 (29%), Positives = 55/138 (39%), Gaps = 15/138 (10%)
Query: 80 GHTGPVLDIDWCPHNDEVIASGSEDCTVMVWQIPEN---GLTSPLTEPVVVLEGH----T 132
GH V W P +D ++ASGS D T +W + EN G T + + GH
Sbjct: 177 GHESEVFICAWNPVSD-LLASGSGDSTARIWNLNENSNGGSTQLVLRHCIREGGHDVPSN 235
Query: 133 KRVGIIAWHPTARNVLLSAGCDNVVLIW--NVGTAEELYRLDSLHPDLIYNVSWNHNGSL 190
K V + W+ +L D IW N A L H I+ + WN G+
Sbjct: 236 KDVTSLDWNSDG-TLLAMGSYDGFARIWTENGNLASTL----GQHKGPIFALKWNKKGNY 290
Query: 191 FCSACKDKSVRIIDPRRG 208
SA DK+ I D G
Sbjct: 291 VLSAGVDKTTIIWDAHTG 308
Score = 42.4 bits (98), Expect = 0.001
Identities = 33/132 (25%), Positives = 55/132 (41%), Gaps = 18/132 (13%)
Query: 81 HTGPVLDIDWCP--------HNDEVIASGSEDCTVMVWQIPENGLTSPLTEPVVVLEGHT 132
H+ + I W P ++ ++AS S D TV +W + + T L + H
Sbjct: 400 HSKEIYTIKWSPTGPATSNPNSSIMLASASFDSTVRLWDVEQGVCTHTLMK-------HQ 452
Query: 133 KRVGIIAWHPTARNVLLSAGCDNVVLIWNVGTAEELYRLDSLHPDLIYNVSWNHNGSLFC 192
+ V +A+ P + L S D V IWN + ++ I+ V WN G
Sbjct: 453 EPVYSVAFSPDGK-YLASGSFDKYVHIWNTQSGSLVHSYQGTGG--IFEVCWNARGDKVG 509
Query: 193 SACKDKSVRIID 204
++ D SV ++D
Sbjct: 510 ASASDGSVCVLD 521
Score = 38.1 bits (87), Expect = 0.018
Identities = 36/128 (28%), Positives = 53/128 (41%), Gaps = 18/128 (14%)
Query: 80 GHTGP----VLDIDWCPHNDEVIASGSEDCTVMVWQIPENG-LTSPLTEPVVVLEGHTKR 134
GH P V +DW + ++A GS D +W ENG L S L + H
Sbjct: 229 GHDVPSNKDVTSLDW-NSDGTLLAMGSYDGFARIWT--ENGNLASTLGQ-------HKGP 278
Query: 135 VGIIAWHPTARNVLLSAGCDNVVLIWNVGTAEELYRLDSLHPDLIYNVSWNHNGSLFCSA 194
+ + W+ N +LSAG D +IW+ T E + H +V W +N F S
Sbjct: 279 IFALKWNKKG-NYVLSAGVDKTTIIWDAHTGEAKQQF-PFHSAPALDVDWQNN-MTFASC 335
Query: 195 CKDKSVRI 202
D + +
Sbjct: 336 STDMCIHV 343
Score = 33.5 bits (75), Expect = 0.45
Identities = 29/105 (27%), Positives = 44/105 (41%), Gaps = 22/105 (20%)
Query: 111 QIPENGLTSPLTEPVVVLEGHTKRVGIIAWHPTARNVLLSAGCDNVVLIWNV------GT 164
+IP N T VL GH V I AW+P + ++L S D+ IWN+ G+
Sbjct: 166 EIPPNKAT--------VLRGHESEVFICAWNPVS-DLLASGSGDSTARIWNLNENSNGGS 216
Query: 165 AEELYR-------LDSLHPDLIYNVSWNHNGSLFCSACKDKSVRI 202
+ + R D + ++ WN +G+L D RI
Sbjct: 217 TQLVLRHCIREGGHDVPSNKDVTSLDWNSDGTLLAMGSYDGFARI 261
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.318 0.135 0.410
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 20,106,069
Number of Sequences: 37866
Number of extensions: 938358
Number of successful extensions: 4161
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 70
Number of HSP's successfully gapped in prelim test: 179
Number of HSP's that attempted gapping in prelim test: 3410
Number of HSP's gapped (non-prelim): 670
length of query: 489
length of database: 18,247,518
effective HSP length: 106
effective length of query: 383
effective length of database: 14,233,722
effective search space: 5451515526
effective search space used: 5451515526
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.