Guide to the Human Genome
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Search of human proteins with 8922673

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|8922673 parvin, alpha [Homo sapiens]
         (372 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|8922673 parvin, alpha [Homo sapiens]                               729   0.0  
gi|20127528 parvin, beta isoform b [Homo sapiens]                     543   e-154
gi|51477696 parvin, beta isoform a [Homo sapiens]                     495   e-140
gi|212286181 parvin, gamma [Homo sapiens]                             253   3e-67
gi|212286179 parvin, gamma [Homo sapiens]                             253   3e-67
gi|11545879 parvin, gamma [Homo sapiens]                              253   3e-67
gi|4557241 actinin, alpha 3 [Homo sapiens]                             50   2e-06
gi|4501893 actinin, alpha 2 [Homo sapiens]                             49   9e-06
gi|12025678 actinin, alpha 4 [Homo sapiens]                            47   4e-05
gi|194097352 actinin, alpha 1 isoform c [Homo sapiens]                 46   5e-05
gi|194097350 actinin, alpha 1 isoform a [Homo sapiens]                 46   5e-05
gi|4501891 actinin, alpha 1 isoform b [Homo sapiens]                   46   5e-05
gi|33188445 microfilament and actin filament cross-linker protei...    43   4e-04
gi|41322919 plectin 1 isoform 8 [Homo sapiens]                         43   5e-04
gi|169218211 PREDICTED: similar to plectin 1, partial [Homo sapi...    42   7e-04
gi|41322916 plectin 1 isoform 6 [Homo sapiens]                         42   7e-04
gi|41322908 plectin 1 isoform 3 [Homo sapiens]                         42   7e-04
gi|47607492 plectin 1 isoform 1 [Homo sapiens]                         42   7e-04
gi|112382250 spectrin, beta, non-erythrocytic 1 isoform 1 [Homo ...    42   9e-04
gi|41322910 plectin 1 isoform 7 [Homo sapiens]                         42   0.001
gi|112382252 spectrin, beta, non-erythrocytic 1 isoform 2 [Homo ...    41   0.002
gi|41322923 plectin 1 isoform 11 [Homo sapiens]                        41   0.002
gi|41322914 plectin 1 isoform 10 [Homo sapiens]                        41   0.002
gi|41322912 plectin 1 isoform 2 [Homo sapiens]                         41   0.002
gi|188595687 gamma filamin isoform b [Homo sapiens]                    41   0.002
gi|116805322 gamma filamin isoform a [Homo sapiens]                    41   0.002
gi|34577047 dystonin isoform 1 [Homo sapiens]                          41   0.002
gi|120953251 neuron navigator 3 [Homo sapiens]                         41   0.002
gi|83816971 DIX domain containing 1 isoform a [Homo sapiens]           40   0.003
gi|221316624 dystonin isoform 4 [Homo sapiens]                         40   0.003

>gi|8922673 parvin, alpha [Homo sapiens]
          Length = 372

 Score =  729 bits (1882), Expect = 0.0
 Identities = 372/372 (100%), Positives = 372/372 (100%)

Query: 1   MATSPQKSPSVPKSPTPKSPPSRKKDDSFLGKLGGTLARRKKAKEVSELQEEGMNAINLP 60
           MATSPQKSPSVPKSPTPKSPPSRKKDDSFLGKLGGTLARRKKAKEVSELQEEGMNAINLP
Sbjct: 1   MATSPQKSPSVPKSPTPKSPPSRKKDDSFLGKLGGTLARRKKAKEVSELQEEGMNAINLP 60

Query: 61  LSPIPFELDPEDTMLEENEVRTMVDPNSRSDPKLQELMKVLIDWINDVLVGERIIVKDLA 120
           LSPIPFELDPEDTMLEENEVRTMVDPNSRSDPKLQELMKVLIDWINDVLVGERIIVKDLA
Sbjct: 61  LSPIPFELDPEDTMLEENEVRTMVDPNSRSDPKLQELMKVLIDWINDVLVGERIIVKDLA 120

Query: 121 EDLYDGQVLQKLFEKLESEKLNVAEVTQSEIAQKQKLQTVLEKINETLKLPPRSIKWNVD 180
           EDLYDGQVLQKLFEKLESEKLNVAEVTQSEIAQKQKLQTVLEKINETLKLPPRSIKWNVD
Sbjct: 121 EDLYDGQVLQKLFEKLESEKLNVAEVTQSEIAQKQKLQTVLEKINETLKLPPRSIKWNVD 180

Query: 181 SVHAKSLVAILHLLVALSQYFRAPIRLPDHVSIQVVVVQKREGILQSRQIQEEITGNTEA 240
           SVHAKSLVAILHLLVALSQYFRAPIRLPDHVSIQVVVVQKREGILQSRQIQEEITGNTEA
Sbjct: 181 SVHAKSLVAILHLLVALSQYFRAPIRLPDHVSIQVVVVQKREGILQSRQIQEEITGNTEA 240

Query: 241 LSGRHERDAFDTLFDHAPDKLNVVKKTLITFVNKHLNKLNLEVTELETQFADGVYLVLLM 300
           LSGRHERDAFDTLFDHAPDKLNVVKKTLITFVNKHLNKLNLEVTELETQFADGVYLVLLM
Sbjct: 241 LSGRHERDAFDTLFDHAPDKLNVVKKTLITFVNKHLNKLNLEVTELETQFADGVYLVLLM 300

Query: 301 GLLEGYFVPLHSFFLTPDSFEQKVLNVSFAFELMQDGGLEKPKPRPEDIVNCDLKSTLRV 360
           GLLEGYFVPLHSFFLTPDSFEQKVLNVSFAFELMQDGGLEKPKPRPEDIVNCDLKSTLRV
Sbjct: 301 GLLEGYFVPLHSFFLTPDSFEQKVLNVSFAFELMQDGGLEKPKPRPEDIVNCDLKSTLRV 360

Query: 361 LYNLFTKYRNVE 372
           LYNLFTKYRNVE
Sbjct: 361 LYNLFTKYRNVE 372


>gi|20127528 parvin, beta isoform b [Homo sapiens]
          Length = 364

 Score =  543 bits (1398), Expect = e-154
 Identities = 272/363 (74%), Positives = 316/363 (87%), Gaps = 1/363 (0%)

Query: 10  SVPKSPTPKSPPSRKKDDSFLGKLGGTLARRKKAKEVSELQEEGMNAINLPLSPIPFELD 69
           S P+SPTP+ P   KKD+SFLGKLGGTLAR+++A+EVS+LQEEG NAIN P+SP   ++ 
Sbjct: 3   SAPRSPTPR-PRRMKKDESFLGKLGGTLARKRRAREVSDLQEEGKNAINSPMSPALVDVH 61

Query: 70  PEDTMLEENEVRTMVDPNSRSDPKLQELMKVLIDWINDVLVGERIIVKDLAEDLYDGQVL 129
           PEDT LEENE RTM+DP S+ DPK +EL+KVL+DWINDVLV ERIIVK L EDLYDGQVL
Sbjct: 62  PEDTQLEENEERTMIDPTSKEDPKFKELVKVLLDWINDVLVEERIIVKQLEEDLYDGQVL 121

Query: 130 QKLFEKLESEKLNVAEVTQSEIAQKQKLQTVLEKINETLKLPPRSIKWNVDSVHAKSLVA 189
           QKL EKL   KLNVAEVTQSEI QKQKLQTVLE +++ L+    +++W+VDS+H K+LVA
Sbjct: 122 QKLLEKLAGCKLNVAEVTQSEIGQKQKLQTVLEAVHDLLRPRGWALRWSVDSIHGKNLVA 181

Query: 190 ILHLLVALSQYFRAPIRLPDHVSIQVVVVQKREGILQSRQIQEEITGNTEALSGRHERDA 249
           ILHLLV+L+ +FRAPIRLP+HV++QVVVV+KREG+L S  I EE+T  TE + GR ERDA
Sbjct: 182 ILHLLVSLAMHFRAPIRLPEHVTVQVVVVRKREGLLHSSHISEELTTTTEMMMGRFERDA 241

Query: 250 FDTLFDHAPDKLNVVKKTLITFVNKHLNKLNLEVTELETQFADGVYLVLLMGLLEGYFVP 309
           FDTLFDHAPDKL+VVKK+LITFVNKHLNKLNLEVTELETQFADGVYLVLLMGLLE YFVP
Sbjct: 242 FDTLFDHAPDKLSVVKKSLITFVNKHLNKLNLEVTELETQFADGVYLVLLMGLLEDYFVP 301

Query: 310 LHSFFLTPDSFEQKVLNVSFAFELMQDGGLEKPKPRPEDIVNCDLKSTLRVLYNLFTKYR 369
           LH F+LTP+SF+QKV NVSFAFELM DGGL+KPK RPED+VN DLKSTLRVLYNLFTKY+
Sbjct: 302 LHHFYLTPESFDQKVHNVSFAFELMLDGGLKKPKARPEDVVNLDLKSTLRVLYNLFTKYK 361

Query: 370 NVE 372
           NVE
Sbjct: 362 NVE 364


>gi|51477696 parvin, beta isoform a [Homo sapiens]
          Length = 397

 Score =  495 bits (1275), Expect = e-140
 Identities = 248/327 (75%), Positives = 285/327 (87%)

Query: 46  VSELQEEGMNAINLPLSPIPFELDPEDTMLEENEVRTMVDPNSRSDPKLQELMKVLIDWI 105
           VS+LQEEG NAIN P+SP   ++ PEDT LEENE RTM+DP S+ DPK +EL+KVL+DWI
Sbjct: 71  VSDLQEEGKNAINSPMSPALVDVHPEDTQLEENEERTMIDPTSKEDPKFKELVKVLLDWI 130

Query: 106 NDVLVGERIIVKDLAEDLYDGQVLQKLFEKLESEKLNVAEVTQSEIAQKQKLQTVLEKIN 165
           NDVLV ERIIVK L EDLYDGQVLQKL EKL   KLNVAEVTQSEI QKQKLQTVLE ++
Sbjct: 131 NDVLVEERIIVKQLEEDLYDGQVLQKLLEKLAGCKLNVAEVTQSEIGQKQKLQTVLEAVH 190

Query: 166 ETLKLPPRSIKWNVDSVHAKSLVAILHLLVALSQYFRAPIRLPDHVSIQVVVVQKREGIL 225
           + L+    +++W+VDS+H K+LVAILHLLV+L+ +FRAPIRLP+HV++QVVVV+KREG+L
Sbjct: 191 DLLRPRGWALRWSVDSIHGKNLVAILHLLVSLAMHFRAPIRLPEHVTVQVVVVRKREGLL 250

Query: 226 QSRQIQEEITGNTEALSGRHERDAFDTLFDHAPDKLNVVKKTLITFVNKHLNKLNLEVTE 285
            S  I EE+T  TE + GR ERDAFDTLFDHAPDKL+VVKK+LITFVNKHLNKLNLEVTE
Sbjct: 251 HSSHISEELTTTTEMMMGRFERDAFDTLFDHAPDKLSVVKKSLITFVNKHLNKLNLEVTE 310

Query: 286 LETQFADGVYLVLLMGLLEGYFVPLHSFFLTPDSFEQKVLNVSFAFELMQDGGLEKPKPR 345
           LETQFADGVYLVLLMGLLE YFVPLH F+LTP+SF+QKV NVSFAFELM DGGL+KPK R
Sbjct: 311 LETQFADGVYLVLLMGLLEDYFVPLHHFYLTPESFDQKVHNVSFAFELMLDGGLKKPKAR 370

Query: 346 PEDIVNCDLKSTLRVLYNLFTKYRNVE 372
           PED+VN DLKSTLRVLYNLFTKY+NVE
Sbjct: 371 PEDVVNLDLKSTLRVLYNLFTKYKNVE 397


>gi|212286181 parvin, gamma [Homo sapiens]
          Length = 331

 Score =  253 bits (645), Expect = 3e-67
 Identities = 131/301 (43%), Positives = 199/301 (66%), Gaps = 5/301 (1%)

Query: 70  PEDTMLEENEVRTMVDPNSRSDPKLQELMKVLIDWINDVLVGERIIVKDLAEDLYDGQVL 129
           P +  L +   +  + P SR DPK +EL KVL++WIN  L+ E I+V+ L ED++DG +L
Sbjct: 19  PAEEELSKGGKKKYLPPTSRKDPKFEELQKVLMEWINATLLPEHIVVRSLEEDMFDGLIL 78

Query: 130 QKLFEKLESEKLNVAEVTQSEIAQKQKLQTVLEKINETLKLPPRSIKWNVDSVHAKSLVA 189
             LF++L + KL   ++  +  +QK KL  VLE +N +L+L     KW+V+S+  K L++
Sbjct: 79  HHLFQRLAALKLEAEDIALTATSQKHKLTVVLEAVNRSLQLEEWQAKWSVESIFNKDLLS 138

Query: 190 ILHLLVALSQYFRAPIRLPDHVSIQVVVVQKREGILQSRQIQEEITGNTEALSGRHE--R 247
            LHLLVAL++ F+  + LP +V ++V+ ++  +  L+S ++ E++   TE  + + E  +
Sbjct: 139 TLHLLVALAKRFQPDLSLPTNVQVEVITIESTKSGLKSEKLVEQL---TEYSTDKDEPPK 195

Query: 248 DAFDTLFDHAPDKLNVVKKTLITFVNKHLNKLNLEVTELETQFADGVYLVLLMGLLEGYF 307
           D FD LF  AP+K+N VK+ ++ FVN+ L++L L V  L+TQFADGV L+LL+G LEG+F
Sbjct: 196 DVFDELFKLAPEKVNAVKEAIVNFVNQKLDRLGLSVQNLDTQFADGVILLLLIGQLEGFF 255

Query: 308 VPLHSFFLTPDSFEQKVLNVSFAFELMQDGGLEKPKPRPEDIVNCDLKSTLRVLYNLFTK 367
           + L  F+LTP+S  + + NV+ A EL++D GL      PEDIVN D KSTLRVLY LF K
Sbjct: 256 LHLKEFYLTPNSPAEMLHNVTLALELLKDEGLLSCPVSPEDIVNKDAKSTLRVLYGLFCK 315

Query: 368 Y 368
           +
Sbjct: 316 H 316


>gi|212286179 parvin, gamma [Homo sapiens]
          Length = 331

 Score =  253 bits (645), Expect = 3e-67
 Identities = 131/301 (43%), Positives = 199/301 (66%), Gaps = 5/301 (1%)

Query: 70  PEDTMLEENEVRTMVDPNSRSDPKLQELMKVLIDWINDVLVGERIIVKDLAEDLYDGQVL 129
           P +  L +   +  + P SR DPK +EL KVL++WIN  L+ E I+V+ L ED++DG +L
Sbjct: 19  PAEEELSKGGKKKYLPPTSRKDPKFEELQKVLMEWINATLLPEHIVVRSLEEDMFDGLIL 78

Query: 130 QKLFEKLESEKLNVAEVTQSEIAQKQKLQTVLEKINETLKLPPRSIKWNVDSVHAKSLVA 189
             LF++L + KL   ++  +  +QK KL  VLE +N +L+L     KW+V+S+  K L++
Sbjct: 79  HHLFQRLAALKLEAEDIALTATSQKHKLTVVLEAVNRSLQLEEWQAKWSVESIFNKDLLS 138

Query: 190 ILHLLVALSQYFRAPIRLPDHVSIQVVVVQKREGILQSRQIQEEITGNTEALSGRHE--R 247
            LHLLVAL++ F+  + LP +V ++V+ ++  +  L+S ++ E++   TE  + + E  +
Sbjct: 139 TLHLLVALAKRFQPDLSLPTNVQVEVITIESTKSGLKSEKLVEQL---TEYSTDKDEPPK 195

Query: 248 DAFDTLFDHAPDKLNVVKKTLITFVNKHLNKLNLEVTELETQFADGVYLVLLMGLLEGYF 307
           D FD LF  AP+K+N VK+ ++ FVN+ L++L L V  L+TQFADGV L+LL+G LEG+F
Sbjct: 196 DVFDELFKLAPEKVNAVKEAIVNFVNQKLDRLGLSVQNLDTQFADGVILLLLIGQLEGFF 255

Query: 308 VPLHSFFLTPDSFEQKVLNVSFAFELMQDGGLEKPKPRPEDIVNCDLKSTLRVLYNLFTK 367
           + L  F+LTP+S  + + NV+ A EL++D GL      PEDIVN D KSTLRVLY LF K
Sbjct: 256 LHLKEFYLTPNSPAEMLHNVTLALELLKDEGLLSCPVSPEDIVNKDAKSTLRVLYGLFCK 315

Query: 368 Y 368
           +
Sbjct: 316 H 316


>gi|11545879 parvin, gamma [Homo sapiens]
          Length = 331

 Score =  253 bits (645), Expect = 3e-67
 Identities = 131/301 (43%), Positives = 199/301 (66%), Gaps = 5/301 (1%)

Query: 70  PEDTMLEENEVRTMVDPNSRSDPKLQELMKVLIDWINDVLVGERIIVKDLAEDLYDGQVL 129
           P +  L +   +  + P SR DPK +EL KVL++WIN  L+ E I+V+ L ED++DG +L
Sbjct: 19  PAEEELSKGGKKKYLPPTSRKDPKFEELQKVLMEWINATLLPEHIVVRSLEEDMFDGLIL 78

Query: 130 QKLFEKLESEKLNVAEVTQSEIAQKQKLQTVLEKINETLKLPPRSIKWNVDSVHAKSLVA 189
             LF++L + KL   ++  +  +QK KL  VLE +N +L+L     KW+V+S+  K L++
Sbjct: 79  HHLFQRLAALKLEAEDIALTATSQKHKLTVVLEAVNRSLQLEEWQAKWSVESIFNKDLLS 138

Query: 190 ILHLLVALSQYFRAPIRLPDHVSIQVVVVQKREGILQSRQIQEEITGNTEALSGRHE--R 247
            LHLLVAL++ F+  + LP +V ++V+ ++  +  L+S ++ E++   TE  + + E  +
Sbjct: 139 TLHLLVALAKRFQPDLSLPTNVQVEVITIESTKSGLKSEKLVEQL---TEYSTDKDEPPK 195

Query: 248 DAFDTLFDHAPDKLNVVKKTLITFVNKHLNKLNLEVTELETQFADGVYLVLLMGLLEGYF 307
           D FD LF  AP+K+N VK+ ++ FVN+ L++L L V  L+TQFADGV L+LL+G LEG+F
Sbjct: 196 DVFDELFKLAPEKVNAVKEAIVNFVNQKLDRLGLSVQNLDTQFADGVILLLLIGQLEGFF 255

Query: 308 VPLHSFFLTPDSFEQKVLNVSFAFELMQDGGLEKPKPRPEDIVNCDLKSTLRVLYNLFTK 367
           + L  F+LTP+S  + + NV+ A EL++D GL      PEDIVN D KSTLRVLY LF K
Sbjct: 256 LHLKEFYLTPNSPAEMLHNVTLALELLKDEGLLSCPVSPEDIVNKDAKSTLRVLYGLFCK 315

Query: 368 Y 368
           +
Sbjct: 316 H 316


>gi|4557241 actinin, alpha 3 [Homo sapiens]
          Length = 901

 Score = 50.4 bits (119), Expect = 2e-06
 Identities = 33/121 (27%), Positives = 62/121 (51%), Gaps = 11/121 (9%)

Query: 251 DTLFDHAPDKLNVVKKTLITFVNKHLNKLNLEVTELETQFADGVYLVLLMGLLEGYFVPL 310
           D L D A +K    +KT   + N HL K   ++  +E  F +G+ L+LL+ ++ G  +P 
Sbjct: 36  DLLLDPAWEKQQ--RKTFTAWCNSHLRKAGTQIENIEEDFRNGLKLMLLLEVISGERLP- 92

Query: 311 HSFFLTPDSFE---QKVLNVSFAFELMQDGGLEKPKPRPEDIVNCDLKSTLRVLYNLFTK 367
                 PD  +    K+ NV+ A + +   G++      E+IV+ +LK TL +++ +  +
Sbjct: 93  -----RPDKGKMRFHKIANVNKALDFIASKGVKLVSIGAEEIVDGNLKMTLGMIWTIILR 147

Query: 368 Y 368
           +
Sbjct: 148 F 148


>gi|4501893 actinin, alpha 2 [Homo sapiens]
          Length = 894

 Score = 48.5 bits (114), Expect = 9e-06
 Identities = 32/121 (26%), Positives = 62/121 (51%), Gaps = 11/121 (9%)

Query: 251 DTLFDHAPDKLNVVKKTLITFVNKHLNKLNLEVTELETQFADGVYLVLLMGLLEGYFVPL 310
           D L D A +K    +KT   + N HL K   ++  +E  F +G+ L+LL+ ++ G  +P 
Sbjct: 29  DLLLDPAWEKQQ--RKTFTAWCNSHLRKAGTQIENIEEDFRNGLKLMLLLEVISGERLP- 85

Query: 311 HSFFLTPDSFE---QKVLNVSFAFELMQDGGLEKPKPRPEDIVNCDLKSTLRVLYNLFTK 367
                 PD  +    K+ NV+ A + +   G++      E+IV+ ++K TL +++ +  +
Sbjct: 86  -----KPDRGKMRFHKIANVNKALDYIASKGVKLVSIGAEEIVDGNVKMTLGMIWTIILR 140

Query: 368 Y 368
           +
Sbjct: 141 F 141


>gi|12025678 actinin, alpha 4 [Homo sapiens]
          Length = 911

 Score = 46.6 bits (109), Expect = 4e-05
 Identities = 31/121 (25%), Positives = 61/121 (50%), Gaps = 11/121 (9%)

Query: 251 DTLFDHAPDKLNVVKKTLITFVNKHLNKLNLEVTELETQFADGVYLVLLMGLLEGYFVPL 310
           D L D A +K    +KT   + N HL K   ++  ++  F DG+ L+LL+ ++ G  +P 
Sbjct: 41  DLLLDPAWEKQQ--RKTFTAWCNSHLRKAGTQIENIDEDFRDGLKLMLLLEVISGERLP- 97

Query: 311 HSFFLTPDSFE---QKVLNVSFAFELMQDGGLEKPKPRPEDIVNCDLKSTLRVLYNLFTK 367
                 P+  +    K+ NV+ A + +   G++      E+IV+ + K TL +++ +  +
Sbjct: 98  -----KPERGKMRVHKINNVNKALDFIASKGVKLVSIGAEEIVDGNAKMTLGMIWTIILR 152

Query: 368 Y 368
           +
Sbjct: 153 F 153


>gi|194097352 actinin, alpha 1 isoform c [Homo sapiens]
          Length = 887

 Score = 46.2 bits (108), Expect = 5e-05
 Identities = 31/121 (25%), Positives = 60/121 (49%), Gaps = 11/121 (9%)

Query: 251 DTLFDHAPDKLNVVKKTLITFVNKHLNKLNLEVTELETQFADGVYLVLLMGLLEGYFVPL 310
           D L D A +K    +KT   + N HL K   ++  +E  F DG+ L+LL+ ++ G     
Sbjct: 22  DLLLDPAWEKQQ--RKTFTAWCNSHLRKAGTQIENIEEDFRDGLKLMLLLEVISG----- 74

Query: 311 HSFFLTPDSFE---QKVLNVSFAFELMQDGGLEKPKPRPEDIVNCDLKSTLRVLYNLFTK 367
                 P+  +    K+ NV+ A + +   G++      E+IV+ ++K TL +++ +  +
Sbjct: 75  -ERLAKPERGKMRVHKISNVNKALDFIASKGVKLVSIGAEEIVDGNVKMTLGMIWTIILR 133

Query: 368 Y 368
           +
Sbjct: 134 F 134


>gi|194097350 actinin, alpha 1 isoform a [Homo sapiens]
          Length = 914

 Score = 46.2 bits (108), Expect = 5e-05
 Identities = 31/121 (25%), Positives = 60/121 (49%), Gaps = 11/121 (9%)

Query: 251 DTLFDHAPDKLNVVKKTLITFVNKHLNKLNLEVTELETQFADGVYLVLLMGLLEGYFVPL 310
           D L D A +K    +KT   + N HL K   ++  +E  F DG+ L+LL+ ++ G     
Sbjct: 22  DLLLDPAWEKQQ--RKTFTAWCNSHLRKAGTQIENIEEDFRDGLKLMLLLEVISG----- 74

Query: 311 HSFFLTPDSFE---QKVLNVSFAFELMQDGGLEKPKPRPEDIVNCDLKSTLRVLYNLFTK 367
                 P+  +    K+ NV+ A + +   G++      E+IV+ ++K TL +++ +  +
Sbjct: 75  -ERLAKPERGKMRVHKISNVNKALDFIASKGVKLVSIGAEEIVDGNVKMTLGMIWTIILR 133

Query: 368 Y 368
           +
Sbjct: 134 F 134


>gi|4501891 actinin, alpha 1 isoform b [Homo sapiens]
          Length = 892

 Score = 46.2 bits (108), Expect = 5e-05
 Identities = 31/121 (25%), Positives = 60/121 (49%), Gaps = 11/121 (9%)

Query: 251 DTLFDHAPDKLNVVKKTLITFVNKHLNKLNLEVTELETQFADGVYLVLLMGLLEGYFVPL 310
           D L D A +K    +KT   + N HL K   ++  +E  F DG+ L+LL+ ++ G     
Sbjct: 22  DLLLDPAWEKQQ--RKTFTAWCNSHLRKAGTQIENIEEDFRDGLKLMLLLEVISG----- 74

Query: 311 HSFFLTPDSFE---QKVLNVSFAFELMQDGGLEKPKPRPEDIVNCDLKSTLRVLYNLFTK 367
                 P+  +    K+ NV+ A + +   G++      E+IV+ ++K TL +++ +  +
Sbjct: 75  -ERLAKPERGKMRVHKISNVNKALDFIASKGVKLVSIGAEEIVDGNVKMTLGMIWTIILR 133

Query: 368 Y 368
           +
Sbjct: 134 F 134


>gi|33188445 microfilament and actin filament cross-linker protein
           isoform a [Homo sapiens]
          Length = 5430

 Score = 43.1 bits (100), Expect = 4e-04
 Identities = 28/113 (24%), Positives = 55/113 (48%), Gaps = 4/113 (3%)

Query: 257 APDKLNVVKKTLITFVNKHLNKLNLEVTELETQFADGVYLVLLMGLLEGYFVPLHSFFLT 316
           A ++  V KKT   +VNKHL K+   + +L     DG  L+ L+ +L G  +P     + 
Sbjct: 73  ADERDRVQKKTFTKWVNKHLMKVRKHINDLYEDLRDGHNLISLLEVLSGIKLPREKGRMR 132

Query: 317 PDSFEQKVLNVSFAFELMQDGGLEKPKPRPEDIVNCDLKSTLRVLYNLFTKYR 369
                 ++ NV  A + ++   ++    R +DI + + K TL +++ +   ++
Sbjct: 133 ----FHRLQNVQIALDFLKQRQVKLVNIRNDDITDGNPKLTLGLIWTIILHFQ 181



 Score = 35.0 bits (79), Expect = 0.11
 Identities = 32/95 (33%), Positives = 43/95 (45%), Gaps = 18/95 (18%)

Query: 61  LSPIPFELDPEDTM-----LEENEVR----TMVDPNSRS-----DPKLQELMKVLIDWIN 106
           LSP P    P DT+     L E + R    +++DP  R+     D + +   K    W+N
Sbjct: 34  LSPCP----PGDTLPWNLPLHEQKKRKSQDSVLDPAERAVVRVADERDRVQKKTFTKWVN 89

Query: 107 DVLVGERIIVKDLAEDLYDGQVLQKLFEKLESEKL 141
             L+  R  + DL EDL DG  L  L E L   KL
Sbjct: 90  KHLMKVRKHINDLYEDLRDGHNLISLLEVLSGIKL 124


>gi|41322919 plectin 1 isoform 8 [Homo sapiens]
          Length = 4547

 Score = 42.7 bits (99), Expect = 5e-04
 Identities = 29/115 (25%), Positives = 55/115 (47%), Gaps = 4/115 (3%)

Query: 255 DHAPDKLNVVKKTLITFVNKHLNKLNLEVTELETQFADGVYLVLLMGLLEGYFVPLHSFF 314
           D   ++  V KKT   +VNKHL K    +++L     DG  L+ L+ +L G  +P     
Sbjct: 35  DEQDERDRVQKKTFTKWVNKHLIKAQRHISDLYEDLRDGHNLISLLEVLSGDSLPREKGR 94

Query: 315 LTPDSFEQKVLNVSFAFELMQDGGLEKPKPRPEDIVNCDLKSTLRVLYNLFTKYR 369
           +       K+ NV  A + ++   ++    R +DI + + K TL +++ +   ++
Sbjct: 95  MR----FHKLQNVQIALDYLRHRQVKLVNIRNDDIADGNPKLTLGLIWTIILHFQ 145



 Score = 31.2 bits (69), Expect = 1.6
 Identities = 16/43 (37%), Positives = 21/43 (48%)

Query: 99  KVLIDWINDVLVGERIIVKDLAEDLYDGQVLQKLFEKLESEKL 141
           K    W+N  L+  +  + DL EDL DG  L  L E L  + L
Sbjct: 46  KTFTKWVNKHLIKAQRHISDLYEDLRDGHNLISLLEVLSGDSL 88


>gi|169218211 PREDICTED: similar to plectin 1, partial [Homo
           sapiens]
          Length = 1369

 Score = 42.4 bits (98), Expect = 7e-04
 Identities = 36/148 (24%), Positives = 68/148 (45%), Gaps = 7/148 (4%)

Query: 225 LQSRQIQEEITGNTEALSGRHERDAFDTLFDHAP---DKLNVVKKTLITFVNKHLNKLNL 281
           L  R+  EE++  T  +    +R       + AP   ++  V KKT   +VNKHL K   
Sbjct: 135 LYRRKELEEVSPETPVVPATTQRTLARPGPEPAPATDERDRVQKKTSTKWVNKHLIKAQR 194

Query: 282 EVTELETQFADGVYLVLLMGLLEGYFVPLHSFFLTPDSFEQKVLNVSFAFELMQDGGLEK 341
            +++L     DG  L+ L+ +L G  +P     +       K+ NV  A + ++   ++ 
Sbjct: 195 HISDLYEDLRDGHNLISLLEVLSGDSLPREKGRMR----FHKLQNVQIALDYLRHRQVKL 250

Query: 342 PKPRPEDIVNCDLKSTLRVLYNLFTKYR 369
              R +DI + + K TL +++ +   ++
Sbjct: 251 VNIRNDDIADGNPKLTLGLIWTIILHFQ 278



 Score = 37.4 bits (85), Expect = 0.022
 Identities = 24/79 (30%), Positives = 33/79 (41%), Gaps = 4/79 (5%)

Query: 67  ELDPEDTMLEENEVRTMVDPNSRSDPKLQEL----MKVLIDWINDVLVGERIIVKDLAED 122
           E+ PE  ++     RT+  P     P   E      K    W+N  L+  +  + DL ED
Sbjct: 143 EVSPETPVVPATTQRTLARPGPEPAPATDERDRVQKKTSTKWVNKHLIKAQRHISDLYED 202

Query: 123 LYDGQVLQKLFEKLESEKL 141
           L DG  L  L E L  + L
Sbjct: 203 LRDGHNLISLLEVLSGDSL 221


>gi|41322916 plectin 1 isoform 6 [Homo sapiens]
          Length = 4684

 Score = 42.4 bits (98), Expect = 7e-04
 Identities = 35/145 (24%), Positives = 67/145 (46%), Gaps = 7/145 (4%)

Query: 228 RQIQEEITGNTEALSGRHERDAFDTLFDHAP---DKLNVVKKTLITFVNKHLNKLNLEVT 284
           R+  EE++  T  +    +R       + AP   ++  V KKT   +VNKHL K    ++
Sbjct: 142 RKELEEVSPETPVVPATTQRTLARPGPEPAPATDERDRVQKKTFTKWVNKHLIKAQRHIS 201

Query: 285 ELETQFADGVYLVLLMGLLEGYFVPLHSFFLTPDSFEQKVLNVSFAFELMQDGGLEKPKP 344
           +L     DG  L+ L+ +L G  +P     +       K+ NV  A + ++   ++    
Sbjct: 202 DLYEDLRDGHNLISLLEVLSGDSLPREKGRMR----FHKLQNVQIALDYLRHRQVKLVNI 257

Query: 345 RPEDIVNCDLKSTLRVLYNLFTKYR 369
           R +DI + + K TL +++ +   ++
Sbjct: 258 RNDDIADGNPKLTLGLIWTIILHFQ 282



 Score = 38.1 bits (87), Expect = 0.013
 Identities = 24/79 (30%), Positives = 33/79 (41%), Gaps = 4/79 (5%)

Query: 67  ELDPEDTMLEENEVRTMVDPNSRSDPKLQEL----MKVLIDWINDVLVGERIIVKDLAED 122
           E+ PE  ++     RT+  P     P   E      K    W+N  L+  +  + DL ED
Sbjct: 147 EVSPETPVVPATTQRTLARPGPEPAPATDERDRVQKKTFTKWVNKHLIKAQRHISDLYED 206

Query: 123 LYDGQVLQKLFEKLESEKL 141
           L DG  L  L E L  + L
Sbjct: 207 LRDGHNLISLLEVLSGDSL 225


>gi|41322908 plectin 1 isoform 3 [Homo sapiens]
          Length = 4525

 Score = 42.4 bits (98), Expect = 7e-04
 Identities = 38/143 (26%), Positives = 64/143 (44%), Gaps = 23/143 (16%)

Query: 227 SRQIQEEITGNTEALSGRHERDAFDTLFDHAPDKLNVVKKTLITFVNKHLNKLNLEVTEL 286
           SR IQ EI+      S + ERD              V KKT   +VNKHL K    +++L
Sbjct: 4   SRAIQNEIS------SLKDERD-------------RVQKKTFTKWVNKHLIKAQRHISDL 44

Query: 287 ETQFADGVYLVLLMGLLEGYFVPLHSFFLTPDSFEQKVLNVSFAFELMQDGGLEKPKPRP 346
                DG  L+ L+ +L G  +P     +       K+ NV  A + ++   ++    R 
Sbjct: 45  YEDLRDGHNLISLLEVLSGDSLPREKGRMR----FHKLQNVQIALDYLRHRQVKLVNIRN 100

Query: 347 EDIVNCDLKSTLRVLYNLFTKYR 369
           +DI + + K TL +++ +   ++
Sbjct: 101 DDIADGNPKLTLGLIWTIILHFQ 123



 Score = 33.9 bits (76), Expect = 0.24
 Identities = 22/74 (29%), Positives = 33/74 (44%), Gaps = 8/74 (10%)

Query: 68  LDPEDTMLEENEVRTMVDPNSRSDPKLQELMKVLIDWINDVLVGERIIVKDLAEDLYDGQ 127
           +DP   +  +NE+ ++ D   R   K          W+N  L+  +  + DL EDL DG 
Sbjct: 1   MDPSRAI--QNEISSLKDERDRVQKK------TFTKWVNKHLIKAQRHISDLYEDLRDGH 52

Query: 128 VLQKLFEKLESEKL 141
            L  L E L  + L
Sbjct: 53  NLISLLEVLSGDSL 66


>gi|47607492 plectin 1 isoform 1 [Homo sapiens]
          Length = 4574

 Score = 42.4 bits (98), Expect = 7e-04
 Identities = 29/113 (25%), Positives = 55/113 (48%), Gaps = 4/113 (3%)

Query: 257 APDKLNVVKKTLITFVNKHLNKLNLEVTELETQFADGVYLVLLMGLLEGYFVPLHSFFLT 316
           A ++  V KKT   +VNKHL K    +++L     DG  L+ L+ +L G  +P     + 
Sbjct: 64  ADERDRVQKKTFTKWVNKHLIKAQRHISDLYEDLRDGHNLISLLEVLSGDSLPREKGRMR 123

Query: 317 PDSFEQKVLNVSFAFELMQDGGLEKPKPRPEDIVNCDLKSTLRVLYNLFTKYR 369
                 K+ NV  A + ++   ++    R +DI + + K TL +++ +   ++
Sbjct: 124 ----FHKLQNVQIALDYLRHRQVKLVNIRNDDIADGNPKLTLGLIWTIILHFQ 172



 Score = 32.3 bits (72), Expect = 0.70
 Identities = 20/65 (30%), Positives = 31/65 (47%), Gaps = 5/65 (7%)

Query: 82  TMVDPNSRS-----DPKLQELMKVLIDWINDVLVGERIIVKDLAEDLYDGQVLQKLFEKL 136
           +++DP  R+     D + +   K    W+N  L+  +  + DL EDL DG  L  L E L
Sbjct: 51  SVLDPAERAVIRIADERDRVQKKTFTKWVNKHLIKAQRHISDLYEDLRDGHNLISLLEVL 110

Query: 137 ESEKL 141
             + L
Sbjct: 111 SGDSL 115


>gi|112382250 spectrin, beta, non-erythrocytic 1 isoform 1 [Homo
           sapiens]
          Length = 2364

 Score = 42.0 bits (97), Expect = 9e-04
 Identities = 28/116 (24%), Positives = 57/116 (49%), Gaps = 9/116 (7%)

Query: 257 APDKLNVVKKTLITFVNKHLNKLNLEVTELETQFADGVYLVLLMGLLEGYFVPLHSFFLT 316
           A ++  V KKT   +VN HL +++  +T+L T   DG  L+ L+ +L G  +P       
Sbjct: 49  ADEREAVQKKTFTKWVNSHLARVSCRITDLYTDLRDGRMLIKLLEVLSGERLP------K 102

Query: 317 PDSFEQKV---LNVSFAFELMQDGGLEKPKPRPEDIVNCDLKSTLRVLYNLFTKYR 369
           P     ++    NV  A + +++  +        DIV+ + + TL +++ +  +++
Sbjct: 103 PTKGRMRIHCLENVDKALQFLKEQRVHLENMGSHDIVDGNHRLTLGLIWTIILRFQ 158



 Score = 33.1 bits (74), Expect = 0.41
 Identities = 17/43 (39%), Positives = 22/43 (51%)

Query: 99  KVLIDWINDVLVGERIIVKDLAEDLYDGQVLQKLFEKLESEKL 141
           K    W+N  L      + DL  DL DG++L KL E L  E+L
Sbjct: 58  KTFTKWVNSHLARVSCRITDLYTDLRDGRMLIKLLEVLSGERL 100


>gi|41322910 plectin 1 isoform 7 [Homo sapiens]
          Length = 4515

 Score = 41.6 bits (96), Expect = 0.001
 Identities = 30/113 (26%), Positives = 56/113 (49%), Gaps = 5/113 (4%)

Query: 258 PDKLN-VVKKTLITFVNKHLNKLNLEVTELETQFADGVYLVLLMGLLEGYFVPLHSFFLT 316
           PD+ + V KKT   +VNKHL K    +++L     DG  L+ L+ +L G  +P     + 
Sbjct: 5   PDERDRVQKKTFTKWVNKHLIKAQRHISDLYEDLRDGHNLISLLEVLSGDSLPREKGRMR 64

Query: 317 PDSFEQKVLNVSFAFELMQDGGLEKPKPRPEDIVNCDLKSTLRVLYNLFTKYR 369
                 K+ NV  A + ++   ++    R +DI + + K TL +++ +   ++
Sbjct: 65  ----FHKLQNVQIALDYLRHRQVKLVNIRNDDIADGNPKLTLGLIWTIILHFQ 113



 Score = 31.2 bits (69), Expect = 1.6
 Identities = 16/43 (37%), Positives = 21/43 (48%)

Query: 99  KVLIDWINDVLVGERIIVKDLAEDLYDGQVLQKLFEKLESEKL 141
           K    W+N  L+  +  + DL EDL DG  L  L E L  + L
Sbjct: 14  KTFTKWVNKHLIKAQRHISDLYEDLRDGHNLISLLEVLSGDSL 56


>gi|112382252 spectrin, beta, non-erythrocytic 1 isoform 2 [Homo
           sapiens]
          Length = 2155

 Score = 41.2 bits (95), Expect = 0.002
 Identities = 27/110 (24%), Positives = 54/110 (49%), Gaps = 9/110 (8%)

Query: 263 VVKKTLITFVNKHLNKLNLEVTELETQFADGVYLVLLMGLLEGYFVPLHSFFLTPDSFEQ 322
           V KKT   +VN HL +++  +T+L T   DG  L+ L+ +L G  +P       P     
Sbjct: 42  VQKKTFTKWVNSHLARVSCRITDLYTDLRDGRMLIKLLEVLSGERLP------KPTKGRM 95

Query: 323 KV---LNVSFAFELMQDGGLEKPKPRPEDIVNCDLKSTLRVLYNLFTKYR 369
           ++    NV  A + +++  +        DIV+ + + TL +++ +  +++
Sbjct: 96  RIHCLENVDKALQFLKEQRVHLENMGSHDIVDGNHRLTLGLIWTIILRFQ 145



 Score = 33.1 bits (74), Expect = 0.41
 Identities = 17/43 (39%), Positives = 22/43 (51%)

Query: 99  KVLIDWINDVLVGERIIVKDLAEDLYDGQVLQKLFEKLESEKL 141
           K    W+N  L      + DL  DL DG++L KL E L  E+L
Sbjct: 45  KTFTKWVNSHLARVSCRITDLYTDLRDGRMLIKLLEVLSGERL 87


>gi|41322923 plectin 1 isoform 11 [Homo sapiens]
          Length = 4547

 Score = 41.2 bits (95), Expect = 0.002
 Identities = 28/107 (26%), Positives = 52/107 (48%), Gaps = 4/107 (3%)

Query: 263 VVKKTLITFVNKHLNKLNLEVTELETQFADGVYLVLLMGLLEGYFVPLHSFFLTPDSFEQ 322
           V KKT   +VNKHL K    +++L     DG  L+ L+ +L G  +P     +       
Sbjct: 43  VQKKTFTKWVNKHLIKAQRHISDLYEDLRDGHNLISLLEVLSGDSLPREKGRMR----FH 98

Query: 323 KVLNVSFAFELMQDGGLEKPKPRPEDIVNCDLKSTLRVLYNLFTKYR 369
           K+ NV  A + ++   ++    R +DI + + K TL +++ +   ++
Sbjct: 99  KLQNVQIALDYLRHRQVKLVNIRNDDIADGNPKLTLGLIWTIILHFQ 145



 Score = 32.7 bits (73), Expect = 0.54
 Identities = 23/80 (28%), Positives = 36/80 (45%), Gaps = 1/80 (1%)

Query: 63  PIPFELDPEDTMLEENEVRTMVDPNS-RSDPKLQELMKVLIDWINDVLVGERIIVKDLAE 121
           P P  L  + T  E+N    ++  +  + D + +   K    W+N  L+  +  + DL E
Sbjct: 9   PQPEGLGRKRTSSEDNLYLAVLRASEGKKDERDRVQKKTFTKWVNKHLIKAQRHISDLYE 68

Query: 122 DLYDGQVLQKLFEKLESEKL 141
           DL DG  L  L E L  + L
Sbjct: 69  DLRDGHNLISLLEVLSGDSL 88


>gi|41322914 plectin 1 isoform 10 [Homo sapiens]
          Length = 4551

 Score = 41.2 bits (95), Expect = 0.002
 Identities = 28/107 (26%), Positives = 52/107 (48%), Gaps = 4/107 (3%)

Query: 263 VVKKTLITFVNKHLNKLNLEVTELETQFADGVYLVLLMGLLEGYFVPLHSFFLTPDSFEQ 322
           V KKT   +VNKHL K    +++L     DG  L+ L+ +L G  +P     +       
Sbjct: 47  VQKKTFTKWVNKHLIKAQRHISDLYEDLRDGHNLISLLEVLSGDSLPREKGRMR----FH 102

Query: 323 KVLNVSFAFELMQDGGLEKPKPRPEDIVNCDLKSTLRVLYNLFTKYR 369
           K+ NV  A + ++   ++    R +DI + + K TL +++ +   ++
Sbjct: 103 KLQNVQIALDYLRHRQVKLVNIRNDDIADGNPKLTLGLIWTIILHFQ 149



 Score = 31.2 bits (69), Expect = 1.6
 Identities = 16/43 (37%), Positives = 21/43 (48%)

Query: 99  KVLIDWINDVLVGERIIVKDLAEDLYDGQVLQKLFEKLESEKL 141
           K    W+N  L+  +  + DL EDL DG  L  L E L  + L
Sbjct: 50  KTFTKWVNKHLIKAQRHISDLYEDLRDGHNLISLLEVLSGDSL 92


>gi|41322912 plectin 1 isoform 2 [Homo sapiens]
          Length = 4533

 Score = 41.2 bits (95), Expect = 0.002
 Identities = 28/107 (26%), Positives = 52/107 (48%), Gaps = 4/107 (3%)

Query: 263 VVKKTLITFVNKHLNKLNLEVTELETQFADGVYLVLLMGLLEGYFVPLHSFFLTPDSFEQ 322
           V KKT   +VNKHL K    +++L     DG  L+ L+ +L G  +P     +       
Sbjct: 29  VQKKTFTKWVNKHLIKAQRHISDLYEDLRDGHNLISLLEVLSGDSLPREKGRMR----FH 84

Query: 323 KVLNVSFAFELMQDGGLEKPKPRPEDIVNCDLKSTLRVLYNLFTKYR 369
           K+ NV  A + ++   ++    R +DI + + K TL +++ +   ++
Sbjct: 85  KLQNVQIALDYLRHRQVKLVNIRNDDIADGNPKLTLGLIWTIILHFQ 131



 Score = 32.7 bits (73), Expect = 0.54
 Identities = 24/79 (30%), Positives = 34/79 (43%), Gaps = 8/79 (10%)

Query: 63  PIPFELDPEDTMLEENEVRTMVDPNSRSDPKLQELMKVLIDWINDVLVGERIIVKDLAED 122
           P+P   D +D +    EVR         D + +   K    W+N  L+  +  + DL ED
Sbjct: 4   PLP---DEQDFIQAYEEVR-----EKYKDERDRVQKKTFTKWVNKHLIKAQRHISDLYED 55

Query: 123 LYDGQVLQKLFEKLESEKL 141
           L DG  L  L E L  + L
Sbjct: 56  LRDGHNLISLLEVLSGDSL 74


>gi|188595687 gamma filamin isoform b [Homo sapiens]
          Length = 2692

 Score = 40.8 bits (94), Expect = 0.002
 Identities = 30/116 (25%), Positives = 58/116 (50%), Gaps = 2/116 (1%)

Query: 253 LFDHAPDKLNVVKKTLITFVNKHLNKLNLEVTELETQFADGVYLVLLMGLLEGYFVPLHS 312
           L + AP K  + + T   + N+HL  +   +T+L+   +DG+ L+ L+ +L    +    
Sbjct: 28  LAEDAPWK-KIQQNTFTRWCNEHLKCVGKRLTDLQRDLSDGLRLIALLEVLSQKRM-YRK 85

Query: 313 FFLTPDSFEQKVLNVSFAFELMQDGGLEKPKPRPEDIVNCDLKSTLRVLYNLFTKY 368
           F   P+  + K+ NVS A E ++   ++      + IV+ +LK  L +++ L   Y
Sbjct: 86  FHPRPNFRQMKLENVSVALEFLEREHIKLVSIDSKAIVDGNLKLILGLIWTLILHY 141


>gi|116805322 gamma filamin isoform a [Homo sapiens]
          Length = 2725

 Score = 40.8 bits (94), Expect = 0.002
 Identities = 30/116 (25%), Positives = 58/116 (50%), Gaps = 2/116 (1%)

Query: 253 LFDHAPDKLNVVKKTLITFVNKHLNKLNLEVTELETQFADGVYLVLLMGLLEGYFVPLHS 312
           L + AP K  + + T   + N+HL  +   +T+L+   +DG+ L+ L+ +L    +    
Sbjct: 28  LAEDAPWK-KIQQNTFTRWCNEHLKCVGKRLTDLQRDLSDGLRLIALLEVLSQKRM-YRK 85

Query: 313 FFLTPDSFEQKVLNVSFAFELMQDGGLEKPKPRPEDIVNCDLKSTLRVLYNLFTKY 368
           F   P+  + K+ NVS A E ++   ++      + IV+ +LK  L +++ L   Y
Sbjct: 86  FHPRPNFRQMKLENVSVALEFLEREHIKLVSIDSKAIVDGNLKLILGLIWTLILHY 141


>gi|34577047 dystonin isoform 1 [Homo sapiens]
          Length = 5497

 Score = 40.8 bits (94), Expect = 0.002
 Identities = 28/119 (23%), Positives = 57/119 (47%), Gaps = 4/119 (3%)

Query: 251 DTLFDHAPDKLNVVKKTLITFVNKHLNKLNLEVTELETQFADGVYLVLLMGLLEGYFVPL 310
           D L  +  ++  V KKT   ++N+HL K+   V +L     DG  L+ L+ +L G  +P 
Sbjct: 24  DVLERYKDERDKVQKKTFTKWINQHLMKVRKHVNDLYEDLRDGHNLISLLEVLSGDTLPR 83

Query: 311 HSFFLTPDSFEQKVLNVSFAFELMQDGGLEKPKPRPEDIVNCDLKSTLRVLYNLFTKYR 369
               +       ++ NV  A + ++   ++    R +DI + + K TL +++ +   ++
Sbjct: 84  EKGRMR----FHRLQNVQIALDYLKRRQVKLVNIRNDDITDGNPKLTLGLIWTIILHFQ 138



 Score = 32.3 bits (72), Expect = 0.70
 Identities = 19/43 (44%), Positives = 21/43 (48%)

Query: 99  KVLIDWINDVLVGERIIVKDLAEDLYDGQVLQKLFEKLESEKL 141
           K    WIN  L+  R  V DL EDL DG  L  L E L  + L
Sbjct: 39  KTFTKWINQHLMKVRKHVNDLYEDLRDGHNLISLLEVLSGDTL 81


>gi|120953251 neuron navigator 3 [Homo sapiens]
          Length = 2363

 Score = 40.8 bits (94), Expect = 0.002
 Identities = 29/110 (26%), Positives = 55/110 (50%), Gaps = 4/110 (3%)

Query: 93  KLQELMKVLIDWINDVLV--GERIIVKDLAEDLYDGQVLQKLFEKLESEKLNVAEVTQSE 150
           K +E  K+  DW N  L   G + ++KDL +D+ DG +L ++ + + +EK  V ++    
Sbjct: 75  KEKEDSKIYTDWANHYLAKSGHKRLIKDLQQDIADGVLLAEIIQIIANEK--VEDINGCP 132

Query: 151 IAQKQKLQTVLEKINETLKLPPRSIKWNVDSVHAKSLVAILHLLVALSQY 200
            +Q Q ++ V   ++            + + +   +L AIL L  +LS+Y
Sbjct: 133 RSQSQMIENVDVCLSFLAARGVNVQGLSAEEIRNGNLKAILGLFFSLSRY 182


>gi|83816971 DIX domain containing 1 isoform a [Homo sapiens]
          Length = 683

 Score = 40.0 bits (92), Expect = 0.003
 Identities = 29/112 (25%), Positives = 63/112 (56%), Gaps = 8/112 (7%)

Query: 95  QELMKVLIDWINDVLVGERII--VKDLAEDLYDGQVLQKLFEKLESEKLNVAEVTQ-SEI 151
           ++ ++  + W+N  L     +  V+DL +DL DG +L  L E +  EKL+  +++  ++ 
Sbjct: 20  EQQLQAYVAWVNAQLKKRPAVKPVQDLRQDLRDGVILAYLIEIVAGEKLSGVQLSPGNQQ 79

Query: 152 AQKQKLQTVLEKI-NETLKLPPRSIKWNVDSVHAKSLVAILHLLVALSQYFR 202
             K  ++ VL+ + ++ +++   S K  VD     +L +I+ L++AL+ +F+
Sbjct: 80  EMKNNVEKVLQFVASKKIRMHQTSAKDIVDG----NLKSIMRLVLALAAHFK 127



 Score = 31.2 bits (69), Expect = 1.6
 Identities = 25/103 (24%), Positives = 47/103 (45%), Gaps = 4/103 (3%)

Query: 269 ITFVNKHLNKLNL--EVTELETQFADGVYLVLLMGLLEGYFVPLHSFFLTPDSFEQKVLN 326
           + +VN  L K      V +L     DGV L  L+ ++ G    L    L+P + ++   N
Sbjct: 27  VAWVNAQLKKRPAVKPVQDLRQDLRDGVILAYLIEIVAGE--KLSGVQLSPGNQQEMKNN 84

Query: 327 VSFAFELMQDGGLEKPKPRPEDIVNCDLKSTLRVLYNLFTKYR 369
           V    + +    +   +   +DIV+ +LKS +R++  L   ++
Sbjct: 85  VEKVLQFVASKKIRMHQTSAKDIVDGNLKSIMRLVLALAAHFK 127


>gi|221316624 dystonin isoform 4 [Homo sapiens]
          Length = 5526

 Score = 40.0 bits (92), Expect = 0.003
 Identities = 27/113 (23%), Positives = 55/113 (48%), Gaps = 4/113 (3%)

Query: 257 APDKLNVVKKTLITFVNKHLNKLNLEVTELETQFADGVYLVLLMGLLEGYFVPLHSFFLT 316
           A ++  V KKT   ++N+HL K+   V +L     DG  L+ L+ +L G  +P     + 
Sbjct: 59  ADERDKVQKKTFTKWINQHLMKVRKHVNDLYEDLRDGHNLISLLEVLSGDTLPREKGRMR 118

Query: 317 PDSFEQKVLNVSFAFELMQDGGLEKPKPRPEDIVNCDLKSTLRVLYNLFTKYR 369
                 ++ NV  A + ++   ++    R +DI + + K TL +++ +   ++
Sbjct: 119 ----FHRLQNVQIALDYLKRRQVKLVNIRNDDITDGNPKLTLGLIWTIILHFQ 167



 Score = 37.0 bits (84), Expect = 0.029
 Identities = 27/99 (27%), Positives = 44/99 (44%), Gaps = 5/99 (5%)

Query: 48  ELQEEGMNAINLPLSPIPFELDPEDTMLEENEVRTMVDPNSRS-----DPKLQELMKVLI 102
           +  ++  +A   P   +P+ L   +    + +  +++DP  R+     D + +   K   
Sbjct: 12  DFSQKSGSASPAPGDTLPWNLPKHERSKRKIQGGSVLDPAERAVLRIADERDKVQKKTFT 71

Query: 103 DWINDVLVGERIIVKDLAEDLYDGQVLQKLFEKLESEKL 141
            WIN  L+  R  V DL EDL DG  L  L E L  + L
Sbjct: 72  KWINQHLMKVRKHVNDLYEDLRDGHNLISLLEVLSGDTL 110


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.316    0.134    0.374 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 13,864,776
Number of Sequences: 37866
Number of extensions: 617150
Number of successful extensions: 3845
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 41
Number of HSP's successfully gapped in prelim test: 56
Number of HSP's that attempted gapping in prelim test: 3715
Number of HSP's gapped (non-prelim): 181
length of query: 372
length of database: 18,247,518
effective HSP length: 104
effective length of query: 268
effective length of database: 14,309,454
effective search space: 3834933672
effective search space used: 3834933672
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 63 (28.9 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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