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Search of human proteins with 8922430
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|8922430 centrosomal protein 27kDa isoform 1 [Homo sapiens]
(235 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|8922430 centrosomal protein 27kDa isoform 1 [Homo sapiens] 469 e-133
gi|194394168 centrosomal protein 27kDa isoform 2 [Homo sapiens] 393 e-110
gi|134948605 ankyrin repeat domain 12 isoform 2 [Homo sapiens] 37 0.011
gi|134948558 ankyrin repeat domain 12 isoform 1 [Homo sapiens] 37 0.011
gi|45505178 cancer antigen 1 [Homo sapiens] 35 0.073
gi|10863889 squamous cell carcinoma antigen recognized by T cell... 35 0.073
gi|153791497 ciliary rootlet coiled-coil [Homo sapiens] 34 0.12
gi|194306559 kinesin light chain 1 isoform 3 [Homo sapiens] 33 0.16
gi|110735431 kinesin light chain 1 isoform 2 [Homo sapiens] 33 0.16
gi|33620730 kinesin light chain 1 isoform 1 [Homo sapiens] 33 0.16
gi|118918407 spectrin repeat containing, nuclear envelope 2 isof... 32 0.47
gi|118918403 spectrin repeat containing, nuclear envelope 2 isof... 32 0.47
gi|41406057 amyloid beta A4 protein isoform c precursor [Homo sa... 32 0.62
gi|41406055 amyloid beta A4 protein isoform b precursor [Homo sa... 32 0.62
gi|4502167 amyloid beta A4 protein isoform a precursor [Homo sap... 32 0.62
gi|209915570 amyloid beta A4 protein isoform e precursor [Homo s... 32 0.62
gi|209915573 amyloid beta A4 protein isoform f precursor [Homo s... 32 0.62
gi|89274173 dynein heavy chain domain 2 isoform 2 [Homo sapiens] 32 0.62
gi|194440727 dynein heavy chain domain 2 isoform 1 [Homo sapiens] 32 0.62
gi|7705415 hook homolog 1 [Homo sapiens] 32 0.62
gi|22538387 A-kinase anchor protein 9 isoform 2 [Homo sapiens] 31 1.1
gi|22538393 A-kinase anchor protein 9 isoform 3 [Homo sapiens] 31 1.1
gi|56549111 optineurin [Homo sapiens] 31 1.1
gi|56549109 optineurin [Homo sapiens] 31 1.1
gi|20149572 optineurin [Homo sapiens] 31 1.1
gi|56549107 optineurin [Homo sapiens] 31 1.1
gi|148596984 golgi autoantigen, golgin subfamily b, macrogolgin ... 31 1.1
gi|22749049 Leber congenital amaurosis 5-like [Homo sapiens] 31 1.1
gi|55741661 hypothetical protein LOC57653 [Homo sapiens] 30 1.4
gi|190194412 thyroid hormone receptor interactor 11 [Homo sapiens] 30 1.4
>gi|8922430 centrosomal protein 27kDa isoform 1 [Homo sapiens]
Length = 235
Score = 469 bits (1207), Expect = e-133
Identities = 235/235 (100%), Positives = 235/235 (100%)
Query: 1 MAAANPWDPASAPNGAGLVLGHFIASGMVNQEMLNMSKKTVSCFVNFTRLQQITNIQAEI 60
MAAANPWDPASAPNGAGLVLGHFIASGMVNQEMLNMSKKTVSCFVNFTRLQQITNIQAEI
Sbjct: 1 MAAANPWDPASAPNGAGLVLGHFIASGMVNQEMLNMSKKTVSCFVNFTRLQQITNIQAEI 60
Query: 61 YQKNLEIELLKLEKDTADVVHPFFLAQKCHTLQSMNNHLEAVLKEKRSLRQRLLKPMCQE 120
YQKNLEIELLKLEKDTADVVHPFFLAQKCHTLQSMNNHLEAVLKEKRSLRQRLLKPMCQE
Sbjct: 61 YQKNLEIELLKLEKDTADVVHPFFLAQKCHTLQSMNNHLEAVLKEKRSLRQRLLKPMCQE 120
Query: 121 NLPIEAVYHRYMVHLLELAVTFIERLETHLETIRNIPHLAANLKKMNQALAKMDILVTET 180
NLPIEAVYHRYMVHLLELAVTFIERLETHLETIRNIPHLAANLKKMNQALAKMDILVTET
Sbjct: 121 NLPIEAVYHRYMVHLLELAVTFIERLETHLETIRNIPHLAANLKKMNQALAKMDILVTET 180
Query: 181 EELAENILKWRKQQNEVSSCIPKILAEESYLYKHDIIMPPLPFTSKVHVQTINAK 235
EELAENILKWRKQQNEVSSCIPKILAEESYLYKHDIIMPPLPFTSKVHVQTINAK
Sbjct: 181 EELAENILKWRKQQNEVSSCIPKILAEESYLYKHDIIMPPLPFTSKVHVQTINAK 235
>gi|194394168 centrosomal protein 27kDa isoform 2 [Homo sapiens]
Length = 204
Score = 393 bits (1009), Expect = e-110
Identities = 204/235 (86%), Positives = 204/235 (86%), Gaps = 31/235 (13%)
Query: 1 MAAANPWDPASAPNGAGLVLGHFIASGMVNQEMLNMSKKTVSCFVNFTRLQQITNIQAEI 60
MAAANPWDPASAPNGAGLVLGHFIASGMVNQ
Sbjct: 1 MAAANPWDPASAPNGAGLVLGHFIASGMVNQ----------------------------- 31
Query: 61 YQKNLEIELLKLEKDTADVVHPFFLAQKCHTLQSMNNHLEAVLKEKRSLRQRLLKPMCQE 120
KNLEIELLKLEKDTADVVHPFFLAQKCHTLQSMNNHLEAVLKEKRSLRQRLLKPMCQE
Sbjct: 32 --KNLEIELLKLEKDTADVVHPFFLAQKCHTLQSMNNHLEAVLKEKRSLRQRLLKPMCQE 89
Query: 121 NLPIEAVYHRYMVHLLELAVTFIERLETHLETIRNIPHLAANLKKMNQALAKMDILVTET 180
NLPIEAVYHRYMVHLLELAVTFIERLETHLETIRNIPHLAANLKKMNQALAKMDILVTET
Sbjct: 90 NLPIEAVYHRYMVHLLELAVTFIERLETHLETIRNIPHLAANLKKMNQALAKMDILVTET 149
Query: 181 EELAENILKWRKQQNEVSSCIPKILAEESYLYKHDIIMPPLPFTSKVHVQTINAK 235
EELAENILKWRKQQNEVSSCIPKILAEESYLYKHDIIMPPLPFTSKVHVQTINAK
Sbjct: 150 EELAENILKWRKQQNEVSSCIPKILAEESYLYKHDIIMPPLPFTSKVHVQTINAK 204
>gi|134948605 ankyrin repeat domain 12 isoform 2 [Homo sapiens]
Length = 2039
Score = 37.4 bits (85), Expect = 0.011
Identities = 43/186 (23%), Positives = 87/186 (46%), Gaps = 25/186 (13%)
Query: 46 NFTRLQQITNIQAEIYQKNLEIELL-KLEKDTADVVHPFFLAQKCHTLQSMN--NHLEAV 102
NF + + ++ + ++L +E KLEK+ D ++ H + N + +
Sbjct: 676 NFFKSDETEDLFLNMEHESLTLEKKSKLEKNIKDDKS----TKEKHVSKERNFKEERDKI 731
Query: 103 LKE-KRSLRQRLLKPMCQE--NLPIE-----------AVYHRYMVHLLELAVTFIERLET 148
KE ++S R+ +K + +E N+P + A+ +HL+E + IE+ E
Sbjct: 732 KKESEKSFREEKIKDLKEERENIPTDKDSEFTSLGMSAIEESIGLHLVEKEID-IEKQEK 790
Query: 149 HLETIRNIPHLAANLKKMNQALAKMDILVTETEELAENILKWRKQQNEVSSCIPKILAEE 208
H++ + P + +K+ + + KM+ E E+ ++ K K + ++S C+ KI E+
Sbjct: 791 HIKESKEKPEKRSQIKEKD--IEKMERKTFEKEKKIKHEHKSEKDKLDLSECVDKI-KEK 847
Query: 209 SYLYKH 214
LY H
Sbjct: 848 DKLYSH 853
>gi|134948558 ankyrin repeat domain 12 isoform 1 [Homo sapiens]
Length = 2062
Score = 37.4 bits (85), Expect = 0.011
Identities = 43/186 (23%), Positives = 87/186 (46%), Gaps = 25/186 (13%)
Query: 46 NFTRLQQITNIQAEIYQKNLEIELL-KLEKDTADVVHPFFLAQKCHTLQSMN--NHLEAV 102
NF + + ++ + ++L +E KLEK+ D ++ H + N + +
Sbjct: 699 NFFKSDETEDLFLNMEHESLTLEKKSKLEKNIKDDKS----TKEKHVSKERNFKEERDKI 754
Query: 103 LKE-KRSLRQRLLKPMCQE--NLPIE-----------AVYHRYMVHLLELAVTFIERLET 148
KE ++S R+ +K + +E N+P + A+ +HL+E + IE+ E
Sbjct: 755 KKESEKSFREEKIKDLKEERENIPTDKDSEFTSLGMSAIEESIGLHLVEKEID-IEKQEK 813
Query: 149 HLETIRNIPHLAANLKKMNQALAKMDILVTETEELAENILKWRKQQNEVSSCIPKILAEE 208
H++ + P + +K+ + + KM+ E E+ ++ K K + ++S C+ KI E+
Sbjct: 814 HIKESKEKPEKRSQIKEKD--IEKMERKTFEKEKKIKHEHKSEKDKLDLSECVDKI-KEK 870
Query: 209 SYLYKH 214
LY H
Sbjct: 871 DKLYSH 876
>gi|45505178 cancer antigen 1 [Homo sapiens]
Length = 641
Score = 34.7 bits (78), Expect = 0.073
Identities = 41/176 (23%), Positives = 76/176 (43%), Gaps = 17/176 (9%)
Query: 30 NQEMLNMSKKTVSCFVNFTRLQQITNIQAEIYQKNLEI-ELLKLEKDTADVVHPFFLAQK 88
++EML + K + N+ LQ+ E+ QKN + + L+++K + ++
Sbjct: 266 DKEMLQLQFKKIKA--NYVCLQE--RYMTEMQQKNKSVSQYLEMDKTLSKK------EEE 315
Query: 89 CHTLQSMNNHLEAVLKEKRSLRQRLLKPMCQENLPIEAVYHRYMVHLLELAVTFIERLET 148
LQ + LE L +R + QE L ++ + + LE RLE
Sbjct: 316 VERLQQLKKELEKATASALDLLKREKEAQEQEFLSLQEEFQKLEKENLEERQKLKSRLEK 375
Query: 149 HLETIRNIPHLAANLKKMNQALAKMDILVTETEELAENI-LKWRKQQNEVSSCIPK 203
L +RN+ ++ N + N K+ + E + EN LK + ++E + +PK
Sbjct: 376 LLTQVRNLQFMSENERTKN---IKLQQQINEVKN--ENAKLKQQVARSEEQNYVPK 426
>gi|10863889 squamous cell carcinoma antigen recognized by T cells 1
[Homo sapiens]
Length = 800
Score = 34.7 bits (78), Expect = 0.073
Identities = 26/85 (30%), Positives = 42/85 (49%), Gaps = 11/85 (12%)
Query: 37 SKKTVSCFVNFTRLQQITNIQAEIYQKNLEIELLKLEKDT------ADVVHPFFLAQKCH 90
S KT S + +++ ++A++ K LE+ +K E T ADV++P L Q+
Sbjct: 107 SSKTSSGDASSLSIEETNKLRAKLGLKPLEVNAIKKEAGTKEEPVTADVINPMALRQREE 166
Query: 91 TLQSMNNHLEAVLKEKRSLRQRLLK 115
+ + A KEKR L Q+L K
Sbjct: 167 LREKL-----AAAKEKRLLNQKLGK 186
>gi|153791497 ciliary rootlet coiled-coil [Homo sapiens]
Length = 2017
Score = 33.9 bits (76), Expect = 0.12
Identities = 42/163 (25%), Positives = 74/163 (45%), Gaps = 10/163 (6%)
Query: 50 LQQITNIQAEIYQKNLEIELLKLEKDTADVVHPFFLAQK-CHTLQSMNNHLEAVLKEKRS 108
+Q + Q E+ + ELL EK +++ H +AQ+ L+ L+A +E R
Sbjct: 581 MQAHEDAQREVQRLRSANELLSREK--SNLAHSLQVAQQQAEELRQEREKLQAAQEELRR 638
Query: 109 LRQRLLKPMCQENLPIEAVYHRYMVHLLELAVTFIERLETHLETIRNIPHLAANLKKMNQ 168
R RL + QE+ + R LE + +E+LE + L + +++
Sbjct: 639 QRDRLEEE--QEDAVQDGARVR---RELERSHRQLEQLEGKRSVLAK--ELVEVREALSR 691
Query: 169 ALAKMDILVTETEELAENILKWRKQQNEVSSCIPKILAEESYL 211
A + D+L E E+AE + K + E+ + K+ AEE+ L
Sbjct: 692 ATLQRDMLQAEKAEVAEALTKAEAGRVELELSMTKLRAEEASL 734
>gi|194306559 kinesin light chain 1 isoform 3 [Homo sapiens]
Length = 618
Score = 33.5 bits (75), Expect = 0.16
Identities = 21/71 (29%), Positives = 38/71 (53%), Gaps = 3/71 (4%)
Query: 88 KCHTLQSMNNHLEAVLKEKRSLRQRLLKPMCQEN--LPIEAVYHRYMVHLLELAVTFIER 145
+ + +++NHL AV EK+ LR + ++ +CQEN L E + + E +V +E
Sbjct: 85 EAQVMMALSNHLNAVESEKQKLRAQ-VRRLCQENQWLRDELANTQQKLQKSEQSVAQLEE 143
Query: 146 LETHLETIRNI 156
+ HLE + +
Sbjct: 144 EKKHLEFMNQL 154
>gi|110735431 kinesin light chain 1 isoform 2 [Homo sapiens]
Length = 573
Score = 33.5 bits (75), Expect = 0.16
Identities = 21/71 (29%), Positives = 38/71 (53%), Gaps = 3/71 (4%)
Query: 88 KCHTLQSMNNHLEAVLKEKRSLRQRLLKPMCQEN--LPIEAVYHRYMVHLLELAVTFIER 145
+ + +++NHL AV EK+ LR + ++ +CQEN L E + + E +V +E
Sbjct: 85 EAQVMMALSNHLNAVESEKQKLRAQ-VRRLCQENQWLRDELANTQQKLQKSEQSVAQLEE 143
Query: 146 LETHLETIRNI 156
+ HLE + +
Sbjct: 144 EKKHLEFMNQL 154
>gi|33620730 kinesin light chain 1 isoform 1 [Homo sapiens]
Length = 560
Score = 33.5 bits (75), Expect = 0.16
Identities = 21/71 (29%), Positives = 38/71 (53%), Gaps = 3/71 (4%)
Query: 88 KCHTLQSMNNHLEAVLKEKRSLRQRLLKPMCQEN--LPIEAVYHRYMVHLLELAVTFIER 145
+ + +++NHL AV EK+ LR + ++ +CQEN L E + + E +V +E
Sbjct: 85 EAQVMMALSNHLNAVESEKQKLRAQ-VRRLCQENQWLRDELANTQQKLQKSEQSVAQLEE 143
Query: 146 LETHLETIRNI 156
+ HLE + +
Sbjct: 144 EKKHLEFMNQL 154
>gi|118918407 spectrin repeat containing, nuclear envelope 2 isoform 5
[Homo sapiens]
Length = 6907
Score = 32.0 bits (71), Expect = 0.47
Identities = 35/141 (24%), Positives = 60/141 (42%), Gaps = 25/141 (17%)
Query: 29 VNQEMLNMSKKTVSCF-VNFTRLQQITNIQAEIYQKNLEIELLKLEKDTADVVHPFFLAQ 87
+ + + ++ SC T LQ I N + + K EI LKLE D+ PF + +
Sbjct: 1137 ITSDFSSEEDRSSSCLQAKLTDLQVIKN-ETDARWKEFEIISLKLENHVNDIKKPFVIKE 1195
Query: 88 KCHTLQSMNNHLEAVLK---EKRSLRQRLLKP-------MCQENLPIEAVYHRYMV---H 134
+ TL+ L+ L E RL+ P +C +LP+ H+ + H
Sbjct: 1196 R-DTLKERERELQMTLNTRMESLETALRLVLPVEKASLLLCGSDLPL----HKMAIQGFH 1250
Query: 135 LLELAVTFIERLETHLETIRN 155
L++ +R+ HL I++
Sbjct: 1251 LID-----ADRIYQHLRNIQD 1266
>gi|118918403 spectrin repeat containing, nuclear envelope 2 isoform 1
[Homo sapiens]
Length = 6885
Score = 32.0 bits (71), Expect = 0.47
Identities = 35/141 (24%), Positives = 60/141 (42%), Gaps = 25/141 (17%)
Query: 29 VNQEMLNMSKKTVSCF-VNFTRLQQITNIQAEIYQKNLEIELLKLEKDTADVVHPFFLAQ 87
+ + + ++ SC T LQ I N + + K EI LKLE D+ PF + +
Sbjct: 1137 ITSDFSSEEDRSSSCLQAKLTDLQVIKN-ETDARWKEFEIISLKLENHVNDIKKPFVIKE 1195
Query: 88 KCHTLQSMNNHLEAVLK---EKRSLRQRLLKP-------MCQENLPIEAVYHRYMV---H 134
+ TL+ L+ L E RL+ P +C +LP+ H+ + H
Sbjct: 1196 R-DTLKERERELQMTLNTRMESLETALRLVLPVEKASLLLCGSDLPL----HKMAIQGFH 1250
Query: 135 LLELAVTFIERLETHLETIRN 155
L++ +R+ HL I++
Sbjct: 1251 LID-----ADRIYQHLRNIQD 1266
>gi|41406057 amyloid beta A4 protein isoform c precursor [Homo
sapiens]
Length = 695
Score = 31.6 bits (70), Expect = 0.62
Identities = 18/68 (26%), Positives = 36/68 (52%), Gaps = 1/68 (1%)
Query: 158 HLAANLKKMNQALAKMDILVTETEELAENILKW-RKQQNEVSSCIPKILAEESYLYKHDI 216
HL ++MNQ+L+ + + EE+ + + + +K+QN + +++E Y +D
Sbjct: 458 HLRVIYERMNQSLSLLYNVPAVAEEIQDEVDELLQKEQNYSDDVLANMISEPRISYGNDA 517
Query: 217 IMPPLPFT 224
+MP L T
Sbjct: 518 LMPSLTET 525
>gi|41406055 amyloid beta A4 protein isoform b precursor [Homo
sapiens]
Length = 751
Score = 31.6 bits (70), Expect = 0.62
Identities = 18/68 (26%), Positives = 36/68 (52%), Gaps = 1/68 (1%)
Query: 158 HLAANLKKMNQALAKMDILVTETEELAENILKW-RKQQNEVSSCIPKILAEESYLYKHDI 216
HL ++MNQ+L+ + + EE+ + + + +K+QN + +++E Y +D
Sbjct: 514 HLRVIYERMNQSLSLLYNVPAVAEEIQDEVDELLQKEQNYSDDVLANMISEPRISYGNDA 573
Query: 217 IMPPLPFT 224
+MP L T
Sbjct: 574 LMPSLTET 581
>gi|4502167 amyloid beta A4 protein isoform a precursor [Homo
sapiens]
Length = 770
Score = 31.6 bits (70), Expect = 0.62
Identities = 18/68 (26%), Positives = 36/68 (52%), Gaps = 1/68 (1%)
Query: 158 HLAANLKKMNQALAKMDILVTETEELAENILKW-RKQQNEVSSCIPKILAEESYLYKHDI 216
HL ++MNQ+L+ + + EE+ + + + +K+QN + +++E Y +D
Sbjct: 533 HLRVIYERMNQSLSLLYNVPAVAEEIQDEVDELLQKEQNYSDDVLANMISEPRISYGNDA 592
Query: 217 IMPPLPFT 224
+MP L T
Sbjct: 593 LMPSLTET 600
>gi|209915570 amyloid beta A4 protein isoform e precursor [Homo
sapiens]
Length = 639
Score = 31.6 bits (70), Expect = 0.62
Identities = 18/68 (26%), Positives = 36/68 (52%), Gaps = 1/68 (1%)
Query: 158 HLAANLKKMNQALAKMDILVTETEELAENILKW-RKQQNEVSSCIPKILAEESYLYKHDI 216
HL ++MNQ+L+ + + EE+ + + + +K+QN + +++E Y +D
Sbjct: 402 HLRVIYERMNQSLSLLYNVPAVAEEIQDEVDELLQKEQNYSDDVLANMISEPRISYGNDA 461
Query: 217 IMPPLPFT 224
+MP L T
Sbjct: 462 LMPSLTET 469
>gi|209915573 amyloid beta A4 protein isoform f precursor [Homo
sapiens]
Length = 714
Score = 31.6 bits (70), Expect = 0.62
Identities = 18/68 (26%), Positives = 36/68 (52%), Gaps = 1/68 (1%)
Query: 158 HLAANLKKMNQALAKMDILVTETEELAENILKW-RKQQNEVSSCIPKILAEESYLYKHDI 216
HL ++MNQ+L+ + + EE+ + + + +K+QN + +++E Y +D
Sbjct: 477 HLRVIYERMNQSLSLLYNVPAVAEEIQDEVDELLQKEQNYSDDVLANMISEPRISYGNDA 536
Query: 217 IMPPLPFT 224
+MP L T
Sbjct: 537 LMPSLTET 544
>gi|89274173 dynein heavy chain domain 2 isoform 2 [Homo sapiens]
Length = 457
Score = 31.6 bits (70), Expect = 0.62
Identities = 23/96 (23%), Positives = 41/96 (42%)
Query: 95 MNNHLEAVLKEKRSLRQRLLKPMCQENLPIEAVYHRYMVHLLELAVTFIERLETHLETIR 154
M+N L+ +L+ +L P Q+ LPI + + +E TF + + L +
Sbjct: 296 MSNQLKDLLRRTVEGFVKLFDPKDQQRLPIFKIELTFDDDKMEFYPTFQDLEDNVLSLVE 355
Query: 155 NIPHLAANLKKMNQALAKMDILVTETEELAENILKW 190
I N++ + L+ V EL E++L W
Sbjct: 356 RIAEALQNVQTIPSWLSGTSTPVNLDTELPEHVLHW 391
>gi|194440727 dynein heavy chain domain 2 isoform 1 [Homo sapiens]
Length = 3092
Score = 31.6 bits (70), Expect = 0.62
Identities = 23/96 (23%), Positives = 41/96 (42%)
Query: 95 MNNHLEAVLKEKRSLRQRLLKPMCQENLPIEAVYHRYMVHLLELAVTFIERLETHLETIR 154
M+N L+ +L+ +L P Q+ LPI + + +E TF + + L +
Sbjct: 296 MSNQLKDLLRRTVEGFVKLFDPKDQQRLPIFKIELTFDDDKMEFYPTFQDLEDNVLSLVE 355
Query: 155 NIPHLAANLKKMNQALAKMDILVTETEELAENILKW 190
I N++ + L+ V EL E++L W
Sbjct: 356 RIAEALQNVQTIPSWLSGTSTPVNLDTELPEHVLHW 391
>gi|7705415 hook homolog 1 [Homo sapiens]
Length = 728
Score = 31.6 bits (70), Expect = 0.62
Identities = 30/132 (22%), Positives = 61/132 (46%), Gaps = 6/132 (4%)
Query: 58 AEIYQKNLEIELLKLEKDTADV-VHPFFLAQKCHTLQSMNNHLEAVLKEKRSLRQRL--L 114
A++ + L+ E +LE D VH L ++ Q N+ L ++ +E R+L+ + L
Sbjct: 250 AQLQLEQLQEENFRLEAAKDDYRVHCEELEKQLIEFQHRNDELTSLAEETRALKDEIDVL 309
Query: 115 KPMCQENLPIEA---VYHRYMVHLLELAVTFIERLETHLETIRNIPHLAANLKKMNQALA 171
+ + +E+ +Y + + L +L ET++ + N L LKK N A
Sbjct: 310 RATSDKANKLESTVEIYRQKLQDLNDLRKQVKTLQETNMMYMHNTVSLEEELKKANAART 369
Query: 172 KMDILVTETEEL 183
+++ + ++L
Sbjct: 370 QLETYKRQVQDL 381
Score = 28.9 bits (63), Expect = 4.0
Identities = 39/178 (21%), Positives = 73/178 (41%), Gaps = 19/178 (10%)
Query: 50 LQQITNIQAEIYQK----NLEIELLKLEKDTADVVHPFFLAQKCHTLQSMNNHLEAVLKE 105
LQ+ + E+ Q+ ++++ L+ EK++ V + +K L + V+ +
Sbjct: 187 LQEALAEKEELRQRCEELDMQVTTLQDEKNSL-VSENEMMNEKLDQLDGSFDDPNTVVAK 245
Query: 106 KRSLRQRLLKPMCQENLPIEAVYHRYMVHLLELAVTFIE------RLETHLETIRNIPHL 159
K Q L+ + +EN +EA Y VH EL IE L + E R +
Sbjct: 246 KYFHAQLQLEQLQEENFRLEAAKDDYRVHCEELEKQLIEFQHRNDELTSLAEETRALKDE 305
Query: 160 AANLKKMNQALAKMDILVTETEELAENILKWRKQQNEVSSCIPKILAEESYLYKHDII 217
L+ + K++ V + +++ RKQ K L E + +Y H+ +
Sbjct: 306 IDVLRATSDKANKLESTVEIYRQKLQDLNDLRKQ--------VKTLQETNMMYMHNTV 355
>gi|22538387 A-kinase anchor protein 9 isoform 2 [Homo sapiens]
Length = 3907
Score = 30.8 bits (68), Expect = 1.1
Identities = 35/179 (19%), Positives = 76/179 (42%), Gaps = 20/179 (11%)
Query: 29 VNQEMLNMSKKTVSCFVNFTRLQQITN-IQAEIYQKNLEIELLKLEKDTA---DVVHPFF 84
+N +++ KKT+ T ++ +Q +I QKN EI+ +KLE + +
Sbjct: 334 LNTKIIEEEKKTLELKDKLTTADKLLGELQEQIVQKNQEIKNMKLELTNSKQKERQSSEE 393
Query: 85 LAQKCHTLQSM--NNHLEAVLKEK--RSLRQRLLKPMCQENLPIEAVY------------ 128
+ Q T++ + NH ++ + + + Q + + Q ++ +Y
Sbjct: 394 IKQLMGTVEELQKRNHKDSQFETDIVQRMEQETQRKLEQLRAELDEMYGQQIVQMKQELI 453
Query: 129 HRYMVHLLELAVTFIERLETHLETIRNIPHLAANLKKMNQALAKMDILVTETEELAENI 187
++M + E+ +E L + NI +K MN A+ +++I + +T E +
Sbjct: 454 RQHMAQMEEMKTRHKGEMENALRSYSNITVNEDQIKLMNVAINELNIKLQDTNSQKEKL 512
>gi|22538393 A-kinase anchor protein 9 isoform 3 [Homo sapiens]
Length = 3899
Score = 30.8 bits (68), Expect = 1.1
Identities = 35/179 (19%), Positives = 76/179 (42%), Gaps = 20/179 (11%)
Query: 29 VNQEMLNMSKKTVSCFVNFTRLQQITN-IQAEIYQKNLEIELLKLEKDTA---DVVHPFF 84
+N +++ KKT+ T ++ +Q +I QKN EI+ +KLE + +
Sbjct: 334 LNTKIIEEEKKTLELKDKLTTADKLLGELQEQIVQKNQEIKNMKLELTNSKQKERQSSEE 393
Query: 85 LAQKCHTLQSM--NNHLEAVLKEK--RSLRQRLLKPMCQENLPIEAVY------------ 128
+ Q T++ + NH ++ + + + Q + + Q ++ +Y
Sbjct: 394 IKQLMGTVEELQKRNHKDSQFETDIVQRMEQETQRKLEQLRAELDEMYGQQIVQMKQELI 453
Query: 129 HRYMVHLLELAVTFIERLETHLETIRNIPHLAANLKKMNQALAKMDILVTETEELAENI 187
++M + E+ +E L + NI +K MN A+ +++I + +T E +
Sbjct: 454 RQHMAQMEEMKTRHKGEMENALRSYSNITVNEDQIKLMNVAINELNIKLQDTNSQKEKL 512
>gi|56549111 optineurin [Homo sapiens]
Length = 577
Score = 30.8 bits (68), Expect = 1.1
Identities = 37/160 (23%), Positives = 72/160 (45%), Gaps = 19/160 (11%)
Query: 52 QITNIQAEIYQKNLEIELLKLEKDTADVVHPFFLAQKCHTLQSMNNHLEAVLKEKRSL-- 109
Q+T++ E+ + + ++ +L K L +KC L+ N+ + + L EK+ L
Sbjct: 305 QVTSLFKELQEAHTKLSEAELMKKR--------LQEKCQALERKNSAIPSELNEKQELVY 356
Query: 110 ----RQRLLKPMCQENLPIEAVYHRYMVHLLELAVTFIERLETHLETIRNIPHLA-ANLK 164
+ ++ M E +A L L +T + L+ H ++ I L +
Sbjct: 357 TNKKLELQVESMLSEIKMEQAKTEDEKSKLTVLQMTHNKLLQEHNNALKTIEELTRKESE 416
Query: 165 KMNQALAKMDILVTETEELAENILKWRK-QQNEVSSCIPK 203
K+++A+ K ++E ELAE L ++ Q +E+ I K
Sbjct: 417 KVDRAVLKE---LSEKLELAEKALASKQLQMDEMKQTIAK 453
>gi|56549109 optineurin [Homo sapiens]
Length = 577
Score = 30.8 bits (68), Expect = 1.1
Identities = 37/160 (23%), Positives = 72/160 (45%), Gaps = 19/160 (11%)
Query: 52 QITNIQAEIYQKNLEIELLKLEKDTADVVHPFFLAQKCHTLQSMNNHLEAVLKEKRSL-- 109
Q+T++ E+ + + ++ +L K L +KC L+ N+ + + L EK+ L
Sbjct: 305 QVTSLFKELQEAHTKLSEAELMKKR--------LQEKCQALERKNSAIPSELNEKQELVY 356
Query: 110 ----RQRLLKPMCQENLPIEAVYHRYMVHLLELAVTFIERLETHLETIRNIPHLA-ANLK 164
+ ++ M E +A L L +T + L+ H ++ I L +
Sbjct: 357 TNKKLELQVESMLSEIKMEQAKTEDEKSKLTVLQMTHNKLLQEHNNALKTIEELTRKESE 416
Query: 165 KMNQALAKMDILVTETEELAENILKWRK-QQNEVSSCIPK 203
K+++A+ K ++E ELAE L ++ Q +E+ I K
Sbjct: 417 KVDRAVLKE---LSEKLELAEKALASKQLQMDEMKQTIAK 453
>gi|20149572 optineurin [Homo sapiens]
Length = 577
Score = 30.8 bits (68), Expect = 1.1
Identities = 37/160 (23%), Positives = 72/160 (45%), Gaps = 19/160 (11%)
Query: 52 QITNIQAEIYQKNLEIELLKLEKDTADVVHPFFLAQKCHTLQSMNNHLEAVLKEKRSL-- 109
Q+T++ E+ + + ++ +L K L +KC L+ N+ + + L EK+ L
Sbjct: 305 QVTSLFKELQEAHTKLSEAELMKKR--------LQEKCQALERKNSAIPSELNEKQELVY 356
Query: 110 ----RQRLLKPMCQENLPIEAVYHRYMVHLLELAVTFIERLETHLETIRNIPHLA-ANLK 164
+ ++ M E +A L L +T + L+ H ++ I L +
Sbjct: 357 TNKKLELQVESMLSEIKMEQAKTEDEKSKLTVLQMTHNKLLQEHNNALKTIEELTRKESE 416
Query: 165 KMNQALAKMDILVTETEELAENILKWRK-QQNEVSSCIPK 203
K+++A+ K ++E ELAE L ++ Q +E+ I K
Sbjct: 417 KVDRAVLKE---LSEKLELAEKALASKQLQMDEMKQTIAK 453
>gi|56549107 optineurin [Homo sapiens]
Length = 577
Score = 30.8 bits (68), Expect = 1.1
Identities = 37/160 (23%), Positives = 72/160 (45%), Gaps = 19/160 (11%)
Query: 52 QITNIQAEIYQKNLEIELLKLEKDTADVVHPFFLAQKCHTLQSMNNHLEAVLKEKRSL-- 109
Q+T++ E+ + + ++ +L K L +KC L+ N+ + + L EK+ L
Sbjct: 305 QVTSLFKELQEAHTKLSEAELMKKR--------LQEKCQALERKNSAIPSELNEKQELVY 356
Query: 110 ----RQRLLKPMCQENLPIEAVYHRYMVHLLELAVTFIERLETHLETIRNIPHLA-ANLK 164
+ ++ M E +A L L +T + L+ H ++ I L +
Sbjct: 357 TNKKLELQVESMLSEIKMEQAKTEDEKSKLTVLQMTHNKLLQEHNNALKTIEELTRKESE 416
Query: 165 KMNQALAKMDILVTETEELAENILKWRK-QQNEVSSCIPK 203
K+++A+ K ++E ELAE L ++ Q +E+ I K
Sbjct: 417 KVDRAVLKE---LSEKLELAEKALASKQLQMDEMKQTIAK 453
>gi|148596984 golgi autoantigen, golgin subfamily b, macrogolgin
(with transmembrane signal), 1 [Homo sapiens]
Length = 3259
Score = 30.8 bits (68), Expect = 1.1
Identities = 25/139 (17%), Positives = 65/139 (46%), Gaps = 18/139 (12%)
Query: 50 LQQITNIQAEIYQKNLEIELLKLEKDT-----ADVVHPFFLAQKCHTLQSMNNHLEAVLK 104
L +T ++A++ K LE+ L + E+ + H L ++ H+L +EA K
Sbjct: 756 LSMVTELRAQV--KQLEMNLAEAERQRRLDYESQTAHDNLLTEQIHSLS-----IEAKSK 808
Query: 105 EKRSLRQRLLKPMCQENLPIEAVYHRYMVHLLELAVTFIERLETHLETIRNIPHLAANLK 164
+ + ++ + E ++ + + L + LE + H+++ ++
Sbjct: 809 DVK------IEVLQNELDDVQLQFSEQSTLIRSLQSQLQNKESEVLEGAERVRHISSKVE 862
Query: 165 KMNQALAKMDILVTETEEL 183
+++QAL++ ++ +T+ ++L
Sbjct: 863 ELSQALSQKELEITKMDQL 881
>gi|22749049 Leber congenital amaurosis 5-like [Homo sapiens]
Length = 670
Score = 30.8 bits (68), Expect = 1.1
Identities = 31/107 (28%), Positives = 48/107 (44%), Gaps = 11/107 (10%)
Query: 92 LQSMNNHLEAVLKEKRSLRQRLLKPM--------CQENLP-IEAVYHRYMVHLLELAVTF 142
L M++ LEA+L E + L+Q L+ + Q NLP I A + + +L +L
Sbjct: 158 LADMHHKLEAILTENQFLKQLQLRHLKAIGKYENSQNNLPQIMAKHQNEVKNLRQLLRKS 217
Query: 143 IERLETHLETIRNIPHLAANLKKMNQALAKM--DILVTETEELAENI 187
E+ T +R K + QAL K+ D + E EEL +
Sbjct: 218 QEKERTLSRKLRETDSQLLKTKDILQALQKLSEDKNLAEREELTHKL 264
>gi|55741661 hypothetical protein LOC57653 [Homo sapiens]
Length = 1646
Score = 30.4 bits (67), Expect = 1.4
Identities = 22/92 (23%), Positives = 38/92 (41%), Gaps = 1/92 (1%)
Query: 28 MVNQEMLNMSKKTVSCFVNFTRLQQITNIQAEIYQKNLEIELLKLEKDTA-DVVHPFFLA 86
++N +L K FVN + + + L L+K+ F +
Sbjct: 449 VMNYALLGNRKALAQLFVNLMESTLQQELDSRHRWQGLVDTWKALKKEALLQSFSEFMAS 508
Query: 87 QKCHTLQSMNNHLEAVLKEKRSLRQRLLKPMC 118
+ HT ++ LE +LK + L+QR LK +C
Sbjct: 509 ESIHTPPAVTKELEVMLKTQNVLQQRRLKHLC 540
>gi|190194412 thyroid hormone receptor interactor 11 [Homo sapiens]
Length = 1979
Score = 30.4 bits (67), Expect = 1.4
Identities = 45/199 (22%), Positives = 84/199 (42%), Gaps = 27/199 (13%)
Query: 31 QEMLNMSKKTVSCFVNFTRLQQITNIQAEIYQKNLEIELLKLEKDTADVVHPFFLAQ--- 87
QE LN+ K+ + +L+ + + Q + E ++ +A V F L Q
Sbjct: 336 QEQLNVEKRQIMEECENLKLECSKLQPSAVKQSDTMTEKERILAQSASVEEVFRLQQALS 395
Query: 88 -------KCHTLQSMNNHLEAVLKEKRSL----RQRLLKPMCQENLPIEAVYHRYMVHLL 136
+ +L N+ E LK K + +++ L +E L + + ++
Sbjct: 396 DAENEIMRLSSLNQDNSLAEDNLKLKMRIEVLEKEKSLLSQEKEELQMSLLKLNNEYEVI 455
Query: 137 ELAVTFIERLETHLETIRNIPHLAANLKKMNQALAKMDILVTETEELAEN--------IL 188
+ T L++ L +R +L A +++NQ++++ + L+ E EEL IL
Sbjct: 456 KSTATRDISLDSELHDLRL--NLEAKEQELNQSISEKETLIAEIEELDRQNQEATKHMIL 513
Query: 189 ---KWRKQQNEVSSCIPKI 204
+ KQQNE S I K+
Sbjct: 514 IKDQLSKQQNEGDSIISKL 532
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.320 0.132 0.379
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 7,987,496
Number of Sequences: 37866
Number of extensions: 305835
Number of successful extensions: 1116
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 14
Number of HSP's successfully gapped in prelim test: 64
Number of HSP's that attempted gapping in prelim test: 1074
Number of HSP's gapped (non-prelim): 107
length of query: 235
length of database: 18,247,518
effective HSP length: 99
effective length of query: 136
effective length of database: 14,498,784
effective search space: 1971834624
effective search space used: 1971834624
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 60 (27.7 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.