BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|8922297 LUC7-like isoform a [Homo sapiens] (325 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|41393554 LUC7-like isoform b [Homo sapiens] 639 0.0 gi|8922297 LUC7-like isoform a [Homo sapiens] 639 0.0 gi|116812577 LUC7-like 2 [Homo sapiens] 523 e-148 gi|52426743 cisplatin resistance-associated overexpressed protei... 204 9e-53 gi|19923485 cisplatin resistance-associated overexpressed protei... 204 9e-53 gi|38146113 arginine/serine-rich coiled-coil 2 isoform b [Homo s... 83 4e-16 gi|38146107 arginine/serine-rich coiled-coil 2 isoform a [Homo s... 83 4e-16 gi|41327773 DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 [Homo sapi... 75 6e-14 gi|29568103 U1 small nuclear ribonucleoprotein 70 kDa [Homo sapi... 70 3e-12 gi|42560244 peptidylprolyl isomerase G [Homo sapiens] 70 3e-12 gi|4826690 DEAH (Asp-Glu-Ala-His) box polypeptide 8 [Homo sapiens] 69 7e-12 gi|239754909 PREDICTED: hypothetical protein [Homo sapiens] 66 5e-11 gi|166235169 PRP38 pre-mRNA processing factor 38 (yeast) domain ... 66 5e-11 gi|55741709 RNA binding motif protein 25 [Homo sapiens] 65 1e-10 gi|239749449 PREDICTED: hypothetical protein [Homo sapiens] 65 1e-10 gi|21040326 SON DNA-binding protein isoform F [Homo sapiens] 65 1e-10 gi|21040314 SON DNA-binding protein isoform B [Homo sapiens] 65 1e-10 gi|239747134 PREDICTED: hypothetical protein XP_002343921 [Homo ... 64 2e-10 gi|116008442 zinc finger CCCH-type containing 13 [Homo sapiens] 64 2e-10 gi|20127499 arginine/serine-rich splicing factor 6 [Homo sapiens] 63 4e-10 gi|41327771 DEAD (Asp-Glu-Ala-Asp) box polypeptide 23 [Homo sapi... 63 4e-10 gi|4759100 splicing factor, arginine/serine-rich 11 [Homo sapiens] 62 5e-10 gi|4827046 U2 small nuclear RNA auxiliary factor 1-like 2 [Homo ... 62 7e-10 gi|24762236 PRP38 pre-mRNA processing factor 38 (yeast) domain c... 62 7e-10 gi|148746195 trichohyalin [Homo sapiens] 62 9e-10 gi|62460633 RNA-binding motif protein 16 [Homo sapiens] 62 9e-10 gi|7662238 apoptotic chromatin condensation inducer 1 [Homo sapi... 61 1e-09 gi|6631100 natural killer-tumor recognition sequence [Homo sapiens] 61 1e-09 gi|119226260 calcium homeostasis endoplasmic reticulum protein [... 61 2e-09 gi|21361282 splicing factor, arginine/serine-rich 4 [Homo sapiens] 60 2e-09 >gi|41393554 LUC7-like isoform b [Homo sapiens] Length = 371 Score = 639 bits (1647), Expect = 0.0 Identities = 325/325 (100%), Positives = 325/325 (100%) Query: 1 MSAQAQMRALLDQLMGTARDGDETRQRVKFTDDRVCKSHLLDCCPHDILAGTRMDLGECT 60 MSAQAQMRALLDQLMGTARDGDETRQRVKFTDDRVCKSHLLDCCPHDILAGTRMDLGECT Sbjct: 1 MSAQAQMRALLDQLMGTARDGDETRQRVKFTDDRVCKSHLLDCCPHDILAGTRMDLGECT 60 Query: 61 KIHDLALRADYEIASKERDLFFELDAMDHLESFIAECDRRTELAKKRLAETQEEISAEVS 120 KIHDLALRADYEIASKERDLFFELDAMDHLESFIAECDRRTELAKKRLAETQEEISAEVS Sbjct: 61 KIHDLALRADYEIASKERDLFFELDAMDHLESFIAECDRRTELAKKRLAETQEEISAEVS 120 Query: 121 AKAEKVHELNEEIGKLLAKAEQLGAEGNVDESQKILMEVEKVRAKKKEAEEEYRNSMPAS 180 AKAEKVHELNEEIGKLLAKAEQLGAEGNVDESQKILMEVEKVRAKKKEAEEEYRNSMPAS Sbjct: 121 AKAEKVHELNEEIGKLLAKAEQLGAEGNVDESQKILMEVEKVRAKKKEAEEEYRNSMPAS 180 Query: 181 SFQQQKLRVCEVCSAYLGLHDNDRRLADHFGGKLHLGFIQIREKLDQLRKTVAEKQEKRN 240 SFQQQKLRVCEVCSAYLGLHDNDRRLADHFGGKLHLGFIQIREKLDQLRKTVAEKQEKRN Sbjct: 181 SFQQQKLRVCEVCSAYLGLHDNDRRLADHFGGKLHLGFIQIREKLDQLRKTVAEKQEKRN 240 Query: 241 QDRLRRREEREREERLSRRSGSRTRDRRRSRSRDRRRRRSRSTSRERRKLSRSRSRDRHR 300 QDRLRRREEREREERLSRRSGSRTRDRRRSRSRDRRRRRSRSTSRERRKLSRSRSRDRHR Sbjct: 241 QDRLRRREEREREERLSRRSGSRTRDRRRSRSRDRRRRRSRSTSRERRKLSRSRSRDRHR 300 Query: 301 RHRSRSRSHSRGHRRASRDRSAKYK 325 RHRSRSRSHSRGHRRASRDRSAKYK Sbjct: 301 RHRSRSRSHSRGHRRASRDRSAKYK 325 >gi|8922297 LUC7-like isoform a [Homo sapiens] Length = 325 Score = 639 bits (1647), Expect = 0.0 Identities = 325/325 (100%), Positives = 325/325 (100%) Query: 1 MSAQAQMRALLDQLMGTARDGDETRQRVKFTDDRVCKSHLLDCCPHDILAGTRMDLGECT 60 MSAQAQMRALLDQLMGTARDGDETRQRVKFTDDRVCKSHLLDCCPHDILAGTRMDLGECT Sbjct: 1 MSAQAQMRALLDQLMGTARDGDETRQRVKFTDDRVCKSHLLDCCPHDILAGTRMDLGECT 60 Query: 61 KIHDLALRADYEIASKERDLFFELDAMDHLESFIAECDRRTELAKKRLAETQEEISAEVS 120 KIHDLALRADYEIASKERDLFFELDAMDHLESFIAECDRRTELAKKRLAETQEEISAEVS Sbjct: 61 KIHDLALRADYEIASKERDLFFELDAMDHLESFIAECDRRTELAKKRLAETQEEISAEVS 120 Query: 121 AKAEKVHELNEEIGKLLAKAEQLGAEGNVDESQKILMEVEKVRAKKKEAEEEYRNSMPAS 180 AKAEKVHELNEEIGKLLAKAEQLGAEGNVDESQKILMEVEKVRAKKKEAEEEYRNSMPAS Sbjct: 121 AKAEKVHELNEEIGKLLAKAEQLGAEGNVDESQKILMEVEKVRAKKKEAEEEYRNSMPAS 180 Query: 181 SFQQQKLRVCEVCSAYLGLHDNDRRLADHFGGKLHLGFIQIREKLDQLRKTVAEKQEKRN 240 SFQQQKLRVCEVCSAYLGLHDNDRRLADHFGGKLHLGFIQIREKLDQLRKTVAEKQEKRN Sbjct: 181 SFQQQKLRVCEVCSAYLGLHDNDRRLADHFGGKLHLGFIQIREKLDQLRKTVAEKQEKRN 240 Query: 241 QDRLRRREEREREERLSRRSGSRTRDRRRSRSRDRRRRRSRSTSRERRKLSRSRSRDRHR 300 QDRLRRREEREREERLSRRSGSRTRDRRRSRSRDRRRRRSRSTSRERRKLSRSRSRDRHR Sbjct: 241 QDRLRRREEREREERLSRRSGSRTRDRRRSRSRDRRRRRSRSTSRERRKLSRSRSRDRHR 300 Query: 301 RHRSRSRSHSRGHRRASRDRSAKYK 325 RHRSRSRSHSRGHRRASRDRSAKYK Sbjct: 301 RHRSRSRSHSRGHRRASRDRSAKYK 325 >gi|116812577 LUC7-like 2 [Homo sapiens] Length = 392 Score = 523 bits (1346), Expect = e-148 Identities = 262/327 (80%), Positives = 300/327 (91%), Gaps = 6/327 (1%) Query: 1 MSAQAQMRALLDQLMGTARDGDETRQRVKFTDDRVCKSHLLDCCPHDILAGTRMDLGECT 60 MSAQAQMRA+LDQLMGT+RDGD TRQR+KF+DDRVCKSHLL+CCPHD+L+GTRMDLGEC Sbjct: 1 MSAQAQMRAMLDQLMGTSRDGDTTRQRIKFSDDRVCKSHLLNCCPHDVLSGTRMDLGECL 60 Query: 61 KIHDLALRADYEIASKERDLFFELDAMDHLESFIAECDRRTELAKKRLAETQEEISAEVS 120 K+HDLALRADYEIASKE+D FFELDAMDHL+SFIA+CDRRTE+AKKRLAETQEEISAEV+ Sbjct: 61 KVHDLALRADYEIASKEQDFFFELDAMDHLQSFIADCDRRTEVAKKRLAETQEEISAEVA 120 Query: 121 AKAEKVHELNEEIGKLLAKAEQLGAEGNVDESQKILMEVEKVRAKKKEAEEEYRNSMPAS 180 AKAE+VHELNEEIGKLLAK EQLGAEGNV+ESQK++ EVEK RAKK+EAEE YRNSMPAS Sbjct: 121 AKAERVHELNEEIGKLLAKVEQLGAEGNVEESQKVMDEVEKARAKKREAEEVYRNSMPAS 180 Query: 181 SFQQQKLRVCEVCSAYLGLHDNDRRLADHFGGKLHLGFIQIREKLDQLRKTVAEKQEKRN 240 SFQQQKLRVCEVCSAYLGLHDNDRRLADHFGGKLHLGFI+IREKL++L++ VAEKQEKRN Sbjct: 181 SFQQQKLRVCEVCSAYLGLHDNDRRLADHFGGKLHLGFIEIREKLEELKRVVAEKQEKRN 240 Query: 241 QDRLRRREEREREERLS-RRSGSRTRDRRRSRSRDRRRRRSRSTSRERRKLSRSRSRDRH 299 Q+RL+RREEREREER RRS S +++ +RSRSR+ RR RSRS SRER++ +RS+SR++ Sbjct: 241 QERLKRREEREREEREKLRRSRSHSKNPKRSRSREHRRHRSRSMSRERKRRTRSKSREKR 300 Query: 300 RRHRSR--SRSHSRGHRR---ASRDRS 321 RHRSR SRS SR H+R +SRDRS Sbjct: 301 HRHRSRSSSRSRSRSHQRSRHSSRDRS 327 >gi|52426743 cisplatin resistance-associated overexpressed protein [Homo sapiens] Length = 432 Score = 204 bits (519), Expect = 9e-53 Identities = 118/326 (36%), Positives = 191/326 (58%), Gaps = 13/326 (3%) Query: 10 LLDQLMGTARD--GDETRQRVKFTDDRVCKSHLLDCCPHDILAGTRMDLGECTKIHDLAL 67 LLD+LMG R+ DE R V++ + VCK +L CP ++ TR DLG C KIHD L Sbjct: 7 LLDELMGRDRNLAPDEKRSNVRWDHESVCKYYLCGFCPAELFTNTRSDLGPCEKIHDENL 66 Query: 68 RADYEIASKERDLFFELDAMDHLESFIAECDRRTELAKKRLAETQEEISAEVSAKA---- 123 R YE +S+ + +E D + +L+S +AE +RR RLA +Q + S+ + Sbjct: 67 RKQYEKSSRFMKVGYERDFLRYLQSLLAEVERRIRRGHARLALSQNQQSSGAAGPTGKNE 126 Query: 124 EKVHELNEEIGKLLAKAEQLGAEGNVDESQKILMEVEKVRAKKKEAEEEYRNSMPASSFQ 183 EK+ L ++I LL + E+LG+EG V+E+Q ++ VE+++ +++E +++ + + Q Sbjct: 127 EKIQVLTDKIDVLLQQIEELGSEGKVEEAQGMMKLVEQLK-EERELLRSTTSTIESFAAQ 185 Query: 184 QQKLRVCEVCSAYLGLHDNDRRLADHFGGKLHLGFIQIREKLDQLRKTVAEKQEKRNQDR 243 ++++ VCEVC A+L + D R+ DH GK H+G+ +I+ +++L++ + ++ E+ ++D Sbjct: 186 EKQMEVCEVCGAFLIVGDAQSRVDDHLMGKQHMGYAKIKATVEELKEKLRKRTEEPDRDE 245 Query: 244 LRRREEREREERLSRRSGSRTRDRRRSRSRDRRRRRSRSTSRERRKLSRSRSRDRHR--- 300 ++E++EREER R R R+ R + R + R+ RERRK SRSRSR R Sbjct: 246 RLKKEKQEREEREKEREREREERERKRRREEEEREKERARDRERRKRSRSRSRHSSRTSD 305 Query: 301 RHRSRSRSHSRG---HRRASRDRSAK 323 R SRSR H R RR SR R + Sbjct: 306 RRCSRSRDHKRSRSRERRRSRSRDRR 331 Score = 62.0 bits (149), Expect = 7e-10 Identities = 53/209 (25%), Positives = 95/209 (45%), Gaps = 21/209 (10%) Query: 117 AEVSAKAEKVHELNEEIGKLLAKAEQLGAEGNVDESQKILMEVEKVRAKKKEAEEEYRNS 176 A++ A E++ E KL + E+ + + + ++ E EK R +++E E E + Sbjct: 221 AKIKATVEELKE------KLRKRTEEPDRDERLKKEKQEREEREKERERERE-ERERKRR 273 Query: 177 MPASSFQQQKLRVCEVCSAYLGLHDNDRRLADHFGGKLHLGFIQIREKLDQLRKTVAEKQ 236 ++++ R E + R +D + D R E++ Sbjct: 274 REEEEREKERARDRERRKRSRSRSRHSSRTSDR----------RCSRSRDHKRSRSRERR 323 Query: 237 EKRNQDRLRRREEREREERLSRRSGSRTRDRRRSRSRDRRRRRSRSTSRERRKLSRSRSR 296 R++DR RR +R ER R SR+RDRRRS+SRDR+ + RS SR+R + +S+ + Sbjct: 324 RSRSRDR-RRSRSHDRSERKHR---SRSRDRRRSKSRDRKSYKHRSKSRDREQDRKSKEK 379 Query: 297 DRHRRHRSRSRSHSRGHRRASRDRSAKYK 325 ++ +S S + S D + + K Sbjct: 380 EKRGSDDKKSSVKSGSREKQSEDTNTESK 408 >gi|19923485 cisplatin resistance-associated overexpressed protein [Homo sapiens] Length = 432 Score = 204 bits (519), Expect = 9e-53 Identities = 118/326 (36%), Positives = 191/326 (58%), Gaps = 13/326 (3%) Query: 10 LLDQLMGTARD--GDETRQRVKFTDDRVCKSHLLDCCPHDILAGTRMDLGECTKIHDLAL 67 LLD+LMG R+ DE R V++ + VCK +L CP ++ TR DLG C KIHD L Sbjct: 7 LLDELMGRDRNLAPDEKRSNVRWDHESVCKYYLCGFCPAELFTNTRSDLGPCEKIHDENL 66 Query: 68 RADYEIASKERDLFFELDAMDHLESFIAECDRRTELAKKRLAETQEEISAEVSAKA---- 123 R YE +S+ + +E D + +L+S +AE +RR RLA +Q + S+ + Sbjct: 67 RKQYEKSSRFMKVGYERDFLRYLQSLLAEVERRIRRGHARLALSQNQQSSGAAGPTGKNE 126 Query: 124 EKVHELNEEIGKLLAKAEQLGAEGNVDESQKILMEVEKVRAKKKEAEEEYRNSMPASSFQ 183 EK+ L ++I LL + E+LG+EG V+E+Q ++ VE+++ +++E +++ + + Q Sbjct: 127 EKIQVLTDKIDVLLQQIEELGSEGKVEEAQGMMKLVEQLK-EERELLRSTTSTIESFAAQ 185 Query: 184 QQKLRVCEVCSAYLGLHDNDRRLADHFGGKLHLGFIQIREKLDQLRKTVAEKQEKRNQDR 243 ++++ VCEVC A+L + D R+ DH GK H+G+ +I+ +++L++ + ++ E+ ++D Sbjct: 186 EKQMEVCEVCGAFLIVGDAQSRVDDHLMGKQHMGYAKIKATVEELKEKLRKRTEEPDRDE 245 Query: 244 LRRREEREREERLSRRSGSRTRDRRRSRSRDRRRRRSRSTSRERRKLSRSRSRDRHR--- 300 ++E++EREER R R R+ R + R + R+ RERRK SRSRSR R Sbjct: 246 RLKKEKQEREEREKEREREREERERKRRREEEEREKERARDRERRKRSRSRSRHSSRTSD 305 Query: 301 RHRSRSRSHSRG---HRRASRDRSAK 323 R SRSR H R RR SR R + Sbjct: 306 RRCSRSRDHKRSRSRERRRSRSRDRR 331 Score = 62.0 bits (149), Expect = 7e-10 Identities = 53/209 (25%), Positives = 95/209 (45%), Gaps = 21/209 (10%) Query: 117 AEVSAKAEKVHELNEEIGKLLAKAEQLGAEGNVDESQKILMEVEKVRAKKKEAEEEYRNS 176 A++ A E++ E KL + E+ + + + ++ E EK R +++E E E + Sbjct: 221 AKIKATVEELKE------KLRKRTEEPDRDERLKKEKQEREEREKERERERE-ERERKRR 273 Query: 177 MPASSFQQQKLRVCEVCSAYLGLHDNDRRLADHFGGKLHLGFIQIREKLDQLRKTVAEKQ 236 ++++ R E + R +D + D R E++ Sbjct: 274 REEEEREKERARDRERRKRSRSRSRHSSRTSDR----------RCSRSRDHKRSRSRERR 323 Query: 237 EKRNQDRLRRREEREREERLSRRSGSRTRDRRRSRSRDRRRRRSRSTSRERRKLSRSRSR 296 R++DR RR +R ER R SR+RDRRRS+SRDR+ + RS SR+R + +S+ + Sbjct: 324 RSRSRDR-RRSRSHDRSERKHR---SRSRDRRRSKSRDRKSYKHRSKSRDREQDRKSKEK 379 Query: 297 DRHRRHRSRSRSHSRGHRRASRDRSAKYK 325 ++ +S S + S D + + K Sbjct: 380 EKRGSDDKKSSVKSGSREKQSEDTNTESK 408 >gi|38146113 arginine/serine-rich coiled-coil 2 isoform b [Homo sapiens] Length = 375 Score = 82.8 bits (203), Expect = 4e-16 Identities = 50/100 (50%), Positives = 64/100 (64%), Gaps = 4/100 (4%) Query: 222 REKLDQLRKTVAEKQEKRNQDRLRRREEREREERLSRRSGSRTRDRRRSRSRDRRRRRSR 281 RE+L+ E + KR + + R R RR SR+R+R++SRSR R R++SR Sbjct: 40 RERLNSSEN--GEDRHKRKERKSSRGRSHSRSRSRERRHRSRSRERKKSRSRSRERKKSR 97 Query: 282 STSRERRKLSRSRSRDRHRRHRSRSRSHSRGHRRASRDRS 321 S SRER+K SRSRSR+R RR RSRSRS SR HR +R RS Sbjct: 98 SRSRERKK-SRSRSRERKRRIRSRSRSRSR-HRHRTRSRS 135 Score = 80.9 bits (198), Expect = 1e-15 Identities = 46/96 (47%), Positives = 62/96 (64%), Gaps = 4/96 (4%) Query: 229 RKTVAEKQEKRNQDRLRRREEREREERLSRRSGSRTRDRRRSRSRDRRRRRSRSTSRERR 288 RK+ + R++ R RR R RE + SR SR+R+R++SRSR R R++SRS SRER+ Sbjct: 58 RKSSRGRSHSRSRSRERRHRSRSRERKKSR---SRSRERKKSRSRSRERKKSRSRSRERK 114 Query: 289 KLSRSRSRDRHR-RHRSRSRSHSRGHRRASRDRSAK 323 + RSRSR R R RHR+RSRS +R R + R K Sbjct: 115 RRIRSRSRSRSRHRHRTRSRSRTRSRSRDRKKRIEK 150 Score = 62.0 bits (149), Expect = 7e-10 Identities = 41/93 (44%), Positives = 51/93 (54%), Gaps = 9/93 (9%) Query: 234 EKQEKRNQDRLRRREEREREERLSRRSGSRTRDRRRSRSRDRRRRRSRSTSRERRKLSRS 293 E + ++RL E E + R SR R RSRSR+RR R S SRER+K SRS Sbjct: 33 EHSSDKGRERLNSSENGEDRHKRKERKSSRGRSHSRSRSRERRHR---SRSRERKK-SRS 88 Query: 294 RSRDRHR-----RHRSRSRSHSRGHRRASRDRS 321 RSR+R + R R +SRS SR +R R RS Sbjct: 89 RSRERKKSRSRSRERKKSRSRSRERKRRIRSRS 121 Score = 58.9 bits (141), Expect = 6e-09 Identities = 38/99 (38%), Positives = 50/99 (50%), Gaps = 4/99 (4%) Query: 230 KTVAEKQEKRNQDRLRRREEREREERLSRRSGSRTRDRRRSRSRDRRRRRSRSTSRERRK 289 K + K+ K + + + ERL+ R +R+ R R R SRS SRERR Sbjct: 17 KDKSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSSRGRSHSRSRSRERRH 76 Query: 290 LSRSRSRDRHR---RHRSRSRSHSRGHRRASRDRSAKYK 325 SRSR R + R R R +SRS SR R+ SR RS + K Sbjct: 77 RSRSRERKKSRSRSRERKKSRSRSR-ERKKSRSRSRERK 114 Score = 55.8 bits (133), Expect = 5e-08 Identities = 47/155 (30%), Positives = 73/155 (47%), Gaps = 13/155 (8%) Query: 161 KVRAKKKEAEEEYRNSMPASSFQQQKLRVCEVCSAYLGLHDNDRRLADHFGGKLHLGFIQ 220 K ++ KK EE+ + +S +++L S+ G + R+ G+ H + Sbjct: 17 KDKSSKKHKSEEHNDKEHSSDKGRERLN-----SSENGEDRHKRKERKSSRGRSHS---R 68 Query: 221 IREKLDQLRKTVAEKQEKRNQDRLRRREEREREERLSRRSGSRTRDRR-----RSRSRDR 275 R + + R E+++ R++ R R++ ER RS SR R RR RSRSR R Sbjct: 69 SRSRERRHRSRSRERKKSRSRSRERKKSRSRSRERKKSRSRSRERKRRIRSRSRSRSRHR 128 Query: 276 RRRRSRSTSRERRKLSRSRSRDRHRRHRSRSRSHS 310 R RSRS +R R + + R R RS SR+ S Sbjct: 129 HRTRSRSRTRSRSRDRKKRIEKPRRFSRSLSRTPS 163 Score = 52.8 bits (125), Expect = 4e-07 Identities = 36/99 (36%), Positives = 53/99 (53%), Gaps = 11/99 (11%) Query: 235 KQEKRNQDRLRRREEREREERLSRR-SGSRTRDRRRS--RSRDRRRRRSRSTSRERRKLS 291 KQ +R++ + + ++ + EE + S + R+R S DR +R+ R +SR R S Sbjct: 9 KQGRRHESKDKSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSSRGR---S 65 Query: 292 RSRSRDRHRRHRSRSRSHSRG-----HRRASRDRSAKYK 325 SRSR R RRHRSRSR + R+ SR RS + K Sbjct: 66 HSRSRSRERRHRSRSRERKKSRSRSRERKKSRSRSRERK 104 >gi|38146107 arginine/serine-rich coiled-coil 2 isoform a [Homo sapiens] Length = 434 Score = 82.8 bits (203), Expect = 4e-16 Identities = 50/100 (50%), Positives = 64/100 (64%), Gaps = 4/100 (4%) Query: 222 REKLDQLRKTVAEKQEKRNQDRLRRREEREREERLSRRSGSRTRDRRRSRSRDRRRRRSR 281 RE+L+ E + KR + + R R RR SR+R+R++SRSR R R++SR Sbjct: 99 RERLNSSEN--GEDRHKRKERKSSRGRSHSRSRSRERRHRSRSRERKKSRSRSRERKKSR 156 Query: 282 STSRERRKLSRSRSRDRHRRHRSRSRSHSRGHRRASRDRS 321 S SRER+K SRSRSR+R RR RSRSRS SR HR +R RS Sbjct: 157 SRSRERKK-SRSRSRERKRRIRSRSRSRSR-HRHRTRSRS 194 Score = 80.9 bits (198), Expect = 1e-15 Identities = 46/96 (47%), Positives = 62/96 (64%), Gaps = 4/96 (4%) Query: 229 RKTVAEKQEKRNQDRLRRREEREREERLSRRSGSRTRDRRRSRSRDRRRRRSRSTSRERR 288 RK+ + R++ R RR R RE + SR SR+R+R++SRSR R R++SRS SRER+ Sbjct: 117 RKSSRGRSHSRSRSRERRHRSRSRERKKSR---SRSRERKKSRSRSRERKKSRSRSRERK 173 Query: 289 KLSRSRSRDRHR-RHRSRSRSHSRGHRRASRDRSAK 323 + RSRSR R R RHR+RSRS +R R + R K Sbjct: 174 RRIRSRSRSRSRHRHRTRSRSRTRSRSRDRKKRIEK 209 Score = 62.0 bits (149), Expect = 7e-10 Identities = 60/220 (27%), Positives = 97/220 (44%), Gaps = 31/220 (14%) Query: 112 QEEISAEVSAKAEKVHELNEEIGKLLAKAEQLGAEGNVDESQKILME----VEKVRAKKK 167 +E+ VS +A K H + + + + EG S+ E K ++ KK Sbjct: 24 KEQSEVSVSPRASK-HHYSRSRSRSRERKRKSDNEGRKHRSRSRSKEGRRHESKDKSSKK 82 Query: 168 EAEEEYRNSMPASSFQQQKLRVCEVCSAYLGLHDNDRRLADHFGGKLHLGFIQIREKLDQ 227 EE+ + +S +++L S+ G + R+ G+ H Sbjct: 83 HKSEEHNDKEHSSDKGRERLN-----SSENGEDRHKRKERKSSRGRSH------------ 125 Query: 228 LRKTVAEKQEKRNQDRLRRREEREREERLSRRSGSRTRDRRRSRSRDRRRRR-----SRS 282 + + +E+R++ R R R++ R ++S SR+R+R++SRSR R R+R SRS Sbjct: 126 ---SRSRSRERRHRSRSRERKKSRSRSRERKKSRSRSRERKKSRSRSRERKRRIRSRSRS 182 Query: 283 TSRER-RKLSRSRSRDRHRRHRSRSRSHSRGHRRASRDRS 321 SR R R SRSR+R R R + R R R SR S Sbjct: 183 RSRHRHRTRSRSRTRSRSRDRKKRIEKPRRFSRSLSRTPS 222 Score = 60.5 bits (145), Expect = 2e-09 Identities = 44/125 (35%), Positives = 61/125 (48%), Gaps = 5/125 (4%) Query: 204 RRLADHFGGKLHLGFIQIREKLDQLRKTVAEKQEKRNQDRLRRREEREREERLSRRSGSR 263 +R +D+ G K H + +E K + K+ K + + + ERL+ Sbjct: 51 KRKSDNEGRK-HRSRSRSKEGRRHESKDKSSKKHKSEEHNDKEHSSDKGRERLNSSENGE 109 Query: 264 TRDRRRSRSRDRRRRRSRSTSRERRKLSRSRSRDRHR---RHRSRSRSHSRGHRRASRDR 320 R +R+ R R R SRS SRERR SRSR R + R R R +SRS SR R+ SR R Sbjct: 110 DRHKRKERKSSRGRSHSRSRSRERRHRSRSRERKKSRSRSRERKKSRSRSR-ERKKSRSR 168 Query: 321 SAKYK 325 S + K Sbjct: 169 SRERK 173 Score = 51.2 bits (121), Expect = 1e-06 Identities = 35/116 (30%), Positives = 56/116 (48%), Gaps = 17/116 (14%) Query: 223 EKLDQLRKTVAEKQEK----RNQDRLRRREEREREERLSRRSGSRTRDRRRSRSRDRRRR 278 +K +Q +V+ + K R++ R R R+ + E RS SR+++ RR S+D+ + Sbjct: 22 KKKEQSEVSVSPRASKHHYSRSRSRSRERKRKSDNEGRKHRSRSRSKEGRRHESKDKSSK 81 Query: 279 RSRSTSRERRKLSRSRSR----------DRHRRHR---SRSRSHSRGHRRASRDRS 321 + +S ++ S + R DRH+R SR RSHSR R R RS Sbjct: 82 KHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSSRGRSHSRSRSRERRHRS 137 Score = 44.7 bits (104), Expect = 1e-04 Identities = 31/98 (31%), Positives = 51/98 (52%), Gaps = 13/98 (13%) Query: 237 EKRNQDRLRRREEREREERLSRRSGSRTRDRRRSRSRDRRRR--------RSRSTSRE-R 287 EK + DR +++E+ E +S R+ R RSRSR+R+R+ RSRS S+E R Sbjct: 14 EKTSPDRDKKKEQSEVS--VSPRASKHHYSRSRSRSRERKRKSDNEGRKHRSRSRSKEGR 71 Query: 288 RKLSRSRSRDRHR--RHRSRSRSHSRGHRRASRDRSAK 323 R S+ +S +H+ H + S +G R + + + Sbjct: 72 RHESKDKSSKKHKSEEHNDKEHSSDKGRERLNSSENGE 109 Score = 28.5 bits (62), Expect = 8.5 Identities = 19/63 (30%), Positives = 26/63 (41%), Gaps = 7/63 (11%) Query: 266 DRRRSRSRDRRRRRSRSTSRERRKLSRSRSRDRHRRHRSRSRSHSR-------GHRRASR 318 D R + R +E+ ++S S +H RSRSRS R G + SR Sbjct: 5 DTERDGLAPEKTSPDRDKKKEQSEVSVSPRASKHHYSRSRSRSRERKRKSDNEGRKHRSR 64 Query: 319 DRS 321 RS Sbjct: 65 SRS 67 >gi|41327773 DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 [Homo sapiens] Length = 1031 Score = 75.5 bits (184), Expect = 6e-14 Identities = 45/97 (46%), Positives = 55/97 (56%), Gaps = 3/97 (3%) Query: 229 RKTVAEKQEKRNQDRLRRREEREREERLSRRSGSRTRDRRRSRSRDRRRRRSRSTSRERR 288 RK A + ++ R R ++ + RRS SR RDRRR RSR R +RRSRS R+R Sbjct: 9 RKRSASRGRSGSRSRSRSPSDKRSKRGDDRRSRSRDRDRRRERSRSRDKRRSRSRDRKRL 68 Query: 289 KLSRSRSRDR---HRRHRSRSRSHSRGHRRASRDRSA 322 + SRSR RDR RR RSR R SR R R RS+ Sbjct: 69 RRSRSRERDRSRERRRSRSRDRRRSRSRSRGRRSRSS 105 Score = 74.3 bits (181), Expect = 1e-13 Identities = 48/96 (50%), Positives = 62/96 (64%), Gaps = 10/96 (10%) Query: 230 KTVAEKQEKRNQDRLRRREEREREERLSRRSGSRTRDRRRSRSRDRRR-RRSRSTSRER- 287 ++ ++K+ KR DR R +R+R RR SR+RD+RRSRSRDR+R RRSRS R+R Sbjct: 25 RSPSDKRSKRGDDRRSRSRDRDR-----RRERSRSRDKRRSRSRDRKRLRRSRSRERDRS 79 Query: 288 RKLSRSRSRDRHRRHRSRSRSHSRGHRRASRDRSAK 323 R+ RSRSRD R RSRSRS R R +S +K Sbjct: 80 RERRRSRSRD---RRRSRSRSRGRRSRSSSPGNKSK 112 Score = 67.0 bits (162), Expect = 2e-11 Identities = 47/89 (52%), Positives = 54/89 (60%), Gaps = 16/89 (17%) Query: 247 REEREREERLSRR--SGSRTRDR------------RRSRSRDRRRRRSRSTSRERRKLSR 292 RE R +R + R SGSR+R R RRSRSRDR RRR RS SR++R+ SR Sbjct: 3 RESRHYRKRSASRGRSGSRSRSRSPSDKRSKRGDDRRSRSRDRDRRRERSRSRDKRR-SR 61 Query: 293 SRSRDRHRRHRSRSRSHSRGHRRA-SRDR 320 SR R R RR RSR R SR RR+ SRDR Sbjct: 62 SRDRKRLRRSRSRERDRSRERRRSRSRDR 90 Score = 58.2 bits (139), Expect = 1e-08 Identities = 35/96 (36%), Positives = 48/96 (50%), Gaps = 1/96 (1%) Query: 229 RKTVAEKQEKRNQDRLRRREEREREERLSR-RSGSRTRDRRRSRSRDRRRRRSRSTSRER 287 R +K+ R++DR R R R RE SR R SR+RDRRRSRSR R RR S+ + Sbjct: 51 RSRSRDKRRSRSRDRKRLRRSRSRERDRSRERRRSRSRDRRRSRSRSRGRRSRSSSPGNK 110 Query: 288 RKLSRSRSRDRHRRHRSRSRSHSRGHRRASRDRSAK 323 K + +RSR + + S + + D K Sbjct: 111 SKKTENRSRSKEKTDGGESSKEKKKDKDDKEDEKEK 146 Score = 53.1 bits (126), Expect = 3e-07 Identities = 41/107 (38%), Positives = 57/107 (53%), Gaps = 12/107 (11%) Query: 229 RKTVAEKQEKRNQDRLRRREE-REREERLSRRSG------SRTRDRRRS----RSRDRRR 277 R + + R++DR RRRE R R++R SR SR+R+R RS RSR R R Sbjct: 31 RSKRGDDRRSRSRDRDRRRERSRSRDKRRSRSRDRKRLRRSRSRERDRSRERRRSRSRDR 90 Query: 278 RRSRSTSRERRKLSRS-RSRDRHRRHRSRSRSHSRGHRRASRDRSAK 323 RRSRS SR RR S S ++ + +RSRS+ + G + + K Sbjct: 91 RRSRSRSRGRRSRSSSPGNKSKKTENRSRSKEKTDGGESSKEKKKDK 137 Score = 32.0 bits (71), Expect = 0.77 Identities = 21/108 (19%), Positives = 46/108 (42%), Gaps = 8/108 (7%) Query: 226 DQLRKTVAEKQEKRNQDRLRRREEREREERLSRRSGSRTRD--------RRRSRSRDRRR 277 D+ R + +E+ RR R+R SR G R+R + +RSR + + Sbjct: 64 DRKRLRRSRSRERDRSRERRRSRSRDRRRSRSRSRGRRSRSSSPGNKSKKTENRSRSKEK 123 Query: 278 RRSRSTSRERRKLSRSRSRDRHRRHRSRSRSHSRGHRRASRDRSAKYK 325 +S+E++K + ++ + + ++ R ++R K++ Sbjct: 124 TDGGESSKEKKKDKDDKEDEKEKDAGNFDQNKLEEEMRKRKERVEKWR 171 >gi|29568103 U1 small nuclear ribonucleoprotein 70 kDa [Homo sapiens] Length = 437 Score = 69.7 bits (169), Expect = 3e-12 Identities = 43/85 (50%), Positives = 52/85 (61%), Gaps = 9/85 (10%) Query: 239 RNQDRLRRREEREREERLSRRSGSRTRDRRRSRSRDRRRRRSRSTSRERRKLSRSRSRDR 298 R++DR R RE RER R + R+RRRSRSRD RRRRSRS +E R+ SR RS+D Sbjct: 231 RDRDRDRERERRERS-----RERDKERERRRSRSRD-RRRRSRSRDKEERRRSRERSKD- 283 Query: 299 HRRHRSRSRSHSRGHRRASRDRSAK 323 + R R R SR RA R+R K Sbjct: 284 --KDRDRKRRSSRSRERARRERERK 306 Score = 61.6 bits (148), Expect = 9e-10 Identities = 37/84 (44%), Positives = 47/84 (55%), Gaps = 4/84 (4%) Query: 241 QDRLRRREEREREERLSRRSGSRTRDRRR---SRSRDRRRRRSRSTSRERRKLSRSRSRD 297 +D R +ER L R R R+R R SR RD+ R R RS SR+RR+ SRSR ++ Sbjct: 213 RDDTSRYDERPGPSPLPHRDRDRDRERERRERSRERDKERERRRSRSRDRRRRSRSRDKE 272 Query: 298 RHRRHRSRSRSHSRGH-RRASRDR 320 RR R RS+ R RR+SR R Sbjct: 273 ERRRSRERSKDKDRDRKRRSSRSR 296 Score = 57.4 bits (137), Expect = 2e-08 Identities = 42/145 (28%), Positives = 60/145 (41%), Gaps = 45/145 (31%) Query: 222 REKLDQLRKTVAEKQEKRNQDRLRRREEREREERLSRRSGSRTRDRRRSRSRDRRRRRSR 281 RE+ ++ R+ E++ +R++ R RRR R R++ RRS R+R + + RDR+RR SR Sbjct: 239 RERRERSRERDKERERRRSRSRDRRRRSRSRDKEERRRS----RERSKDKDRDRKRRSSR 294 Query: 282 STSRERRKLSR-----------------------------------------SRSRDRHR 300 S R RR+ R R RDR R Sbjct: 295 SRERARRERERKEELRGGGGDMAEPSEAGDAPPDDGPPGELGPDGPDGPEEKGRDRDRER 354 Query: 301 RHRSRSRSHSRGHRRASRDRSAKYK 325 R RS R R RDR ++K Sbjct: 355 RRSHRSERERRRDRDRDRDRDREHK 379 Score = 55.5 bits (132), Expect = 6e-08 Identities = 37/84 (44%), Positives = 42/84 (50%), Gaps = 7/84 (8%) Query: 246 RREEREREERLSRRSGSRT---RDRRRSRSRDRRRR-RSRSTSRERRKLSRSRSRDRHRR 301 R R+ R R G RDR R R R+RR R R R RERR RSRSRDR RR Sbjct: 209 RHSGRDDTSRYDERPGPSPLPHRDRDRDRERERRERSRERDKERERR---RSRSRDRRRR 265 Query: 302 HRSRSRSHSRGHRRASRDRSAKYK 325 RSR + R R S+D+ K Sbjct: 266 SRSRDKEERRRSRERSKDKDRDRK 289 Score = 50.8 bits (120), Expect = 2e-06 Identities = 36/109 (33%), Positives = 43/109 (39%), Gaps = 27/109 (24%) Query: 234 EKQEKRNQDRLRRREEREREERLSRRSG-------SRTRD-------------------R 267 ++ KR R R R RERE + R G S D Sbjct: 285 DRDRKRRSSRSRERARRERERKEELRGGGGDMAEPSEAGDAPPDDGPPGELGPDGPDGPE 344 Query: 268 RRSRSRDRRRRRSRSTSRERRKLSRSRSRDRHRRHRSRSRSHSRGHRRA 316 + R RDR RRRS + RERR+ R R RDR R H+ R RG A Sbjct: 345 EKGRDRDRERRRSHRSERERRR-DRDRDRDRDREHKRGERGSERGRDEA 392 Score = 45.8 bits (107), Expect = 5e-05 Identities = 32/82 (39%), Positives = 39/82 (47%), Gaps = 6/82 (7%) Query: 246 RREEREREERLSRRSGSRTRDRRRSRSRDRRRRRSRSTSRERRKLSRSRSRDRHRR---- 301 RR + R S R + D R S R R R RERR+ SR R ++R RR Sbjct: 200 RRGGADVNIRHSGRDDTSRYDERPGPSPLPHRDRDRDRERERRERSRERDKERERRRSRS 259 Query: 302 --HRSRSRSHSRGHRRASRDRS 321 R RSRS + RR SR+RS Sbjct: 260 RDRRRRSRSRDKEERRRSRERS 281 Score = 35.4 bits (80), Expect = 0.070 Identities = 21/56 (37%), Positives = 26/56 (46%), Gaps = 6/56 (10%) Query: 237 EKRNQDRLRRREEREREERLSRRSGSRTRDRRRSRSRDRRRRRSRSTSRERRKLSR 292 E++ +DR R R R ER R RDR R R RDR +R S R +R Sbjct: 344 EEKGRDRDRERRRSHRSER------ERRRDRDRDRDRDREHKRGERGSERGRDEAR 393 Score = 33.9 bits (76), Expect = 0.20 Identities = 26/71 (36%), Positives = 32/71 (45%), Gaps = 7/71 (9%) Query: 249 EREREERLSRRSGSRTRDRRRSRSRDRRRRRSRSTSRERRKLSRSRSRDRHRRHRSRSRS 308 +R+RE R S RS R+RRR R RDR R R +R + R RD R + Sbjct: 349 DRDRERRRSHRS---ERERRRDRDRDRDRDR----EHKRGERGSERGRDEARGGGGGQDN 401 Query: 309 HSRGHRRASRD 319 G SRD Sbjct: 402 GLEGLGNDSRD 412 >gi|42560244 peptidylprolyl isomerase G [Homo sapiens] Length = 754 Score = 69.7 bits (169), Expect = 3e-12 Identities = 77/276 (27%), Positives = 121/276 (43%), Gaps = 44/276 (15%) Query: 70 DYEIASKERDLFFELDAMDHLESFIAECDRRTELAKKRLAETQEEISAEVSAKAEKVHEL 129 D++ SKERD+ + D ++ + KKR S E S E+ + Sbjct: 428 DHKSNSKERDIRRNSEKDDKYKNKV----------KKRAKSKSRSKSKEKSKSKERDSKH 477 Query: 130 NEEIGKLLAKAEQLGAEGNVDESQKIL----MEVEKVRAKKKEAEEEYRNSMPASSFQQQ 185 N K + + NV E +K + E+ R+K+K + E +++ S ++ Sbjct: 478 NRNEEKRMRSRSKGRDHENVKEKEKQSDSKGKDQERSRSKEKSKQLESKSNEHDHSKSKE 537 Query: 186 KLRVCEVCSAYLGLHDNDRRLADHFGGKLHLGFIQIREKLDQLRKTVAEKQEKRNQDRLR 245 K R + S R D GK H + RE+ ++ + ++DR R Sbjct: 538 KDRRAQSRS----------RECDITKGK-HSYNSRTRERSRSRDRSRRVRSRTHDRDRSR 586 Query: 246 RRE-EREREERLSRRSGSRTRDRR----RSRSRDRRRRRSRSTSRERRKLSRSRSRDRHR 300 +E R RE+ RR SR+R+RR RSRS+DRRRRR S S ER + S+SR++D++R Sbjct: 587 SKEYHRYREQEYRRRGRSRSRERRTPPGRSRSKDRRRRRRDSRSSEREE-SQSRNKDKYR 645 Query: 301 RHRSRSR-------------SHSRGHRRASRDRSAK 323 S+S S SR H ++ R K Sbjct: 646 NQESKSSHRKENSESEKRMYSKSRDHNSSNNSREKK 681 Score = 60.5 bits (145), Expect = 2e-09 Identities = 64/255 (25%), Positives = 106/255 (41%), Gaps = 30/255 (11%) Query: 94 IAECDRRTELAKKRLAETQEEISAEVSAKAEKVHELNEEIGKLLAKAEQLGAEGNVDESQ 153 I E R K+R +S + K EK ++ + K +K + D+ Sbjct: 391 IKENQRSPVRVKERKITDHRNVSESPNRKNEKEKKVKDH--KSNSKERDIRRNSEKDDKY 448 Query: 154 KILMEVE---KVRAKKKEAEEEYRNSMPASSFQQQKLRVCEVCSAYLGLHD----NDRRL 206 K ++ K R+K KE + + +++++R + + + +D + Sbjct: 449 KNKVKKRAKSKSRSKSKEKSKSKERDSKHNRNEEKRMRSRSKGRDHENVKEKEKQSDSKG 508 Query: 207 ADHFGGKLHLGFIQIREKLDQLRKTVAEKQEKRNQDRLR-------------RREERERE 253 D + Q+ K ++ + ++++++R Q R R R ER R Sbjct: 509 KDQERSRSKEKSKQLESKSNEHDHSKSKEKDRRAQSRSRECDITKGKHSYNSRTRERSRS 568 Query: 254 ERLSRRSGSRTRDRRRSRSRD-------RRRRRSRSTSRERR-KLSRSRSRDRHRRHRSR 305 SRR SRT DR RSRS++ RRR RS SRERR RSRS+DR RR R Sbjct: 569 RDRSRRVRSRTHDRDRSRSKEYHRYREQEYRRRGRSRSRERRTPPGRSRSKDRRRRRRDS 628 Query: 306 SRSHSRGHRRASRDR 320 S + ++D+ Sbjct: 629 RSSEREESQSRNKDK 643 Score = 44.7 bits (104), Expect = 1e-04 Identities = 31/100 (31%), Positives = 55/100 (55%), Gaps = 14/100 (14%) Query: 236 QEKRNQDRLRRREEREREERLSRRSGSRTRDRRRSRSRDRRRR---------RSRSTSRE 286 +EKR + R + R+ +E+ ++S S+ +D+ RSRS+++ ++ S+S ++ Sbjct: 481 EEKRMRSRSKGRDHENVKEK-EKQSDSKGKDQERSRSKEKSKQLESKSNEHDHSKSKEKD 539 Query: 287 RRKLSRSRSRDRHR-RHRSRSRSHSRGHRRASRDRSAKYK 325 RR SRSR D + +H SR+ R SRDRS + + Sbjct: 540 RRAQSRSRECDITKGKHSYNSRTRERSR---SRDRSRRVR 576 Score = 43.1 bits (100), Expect = 3e-04 Identities = 26/103 (25%), Positives = 53/103 (51%), Gaps = 10/103 (9%) Query: 229 RKTVAEKQEKRNQDRLRRREER---EREERLSRRSGSRTRDRRRSRSRDRRRRRSRSTSR 285 RK EK+ K ++ + R+ R E++++ + R + + RS+S+++ + + R + Sbjct: 418 RKNEKEKKVKDHKSNSKERDIRRNSEKDDKYKNKVKKRAKSKSRSKSKEKSKSKERDSKH 477 Query: 286 ERRKLSRSRSRDRHRRHRS----RSRSHSRG---HRRASRDRS 321 R + R RSR + R H + +S S+G R S+++S Sbjct: 478 NRNEEKRMRSRSKGRDHENVKEKEKQSDSKGKDQERSRSKEKS 520 Score = 42.7 bits (99), Expect = 4e-04 Identities = 31/102 (30%), Positives = 54/102 (52%), Gaps = 11/102 (10%) Query: 235 KQEKRNQDRLRRREEREREERLSRRSGSRTRDRRRSRSRDR-RRRRSRS-----TSRERR 288 K++++ D + +ER R + S++ S++ + S+S+++ RR +SRS T + Sbjct: 498 KEKEKQSDSKGKDQERSRSKEKSKQLESKSNEHDHSKSKEKDRRAQSRSRECDITKGKHS 557 Query: 289 KLSRSRSR--DRHRRHRSRSRSHSRGHRRAS---RDRSAKYK 325 SR+R R R R R RSR+H R R+ R R +Y+ Sbjct: 558 YNSRTRERSRSRDRSRRVRSRTHDRDRSRSKEYHRYREQEYR 599 Score = 37.0 bits (84), Expect = 0.024 Identities = 31/100 (31%), Positives = 44/100 (44%), Gaps = 6/100 (6%) Query: 228 LRKTVAEKQEKRNQDRLRRREEREREERLSRRSGSR----TRDRRRSRSRDRRRRR--SR 281 +RK+ + EK ++R R RE S R TR R+ + R RR R SR Sbjct: 287 MRKSPPKADEKERKNRERERERECNPPNSQPASYQRRLLVTRSGRKIKGRGPRRYRTPSR 346 Query: 282 STSRERRKLSRSRSRDRHRRHRSRSRSHSRGHRRASRDRS 321 S SR+R + S + R R++ S G R D+S Sbjct: 347 SRSRDRFRRSETPPHWRQEMQRAQRMRVSSGERWIKGDKS 386 Score = 33.9 bits (76), Expect = 0.20 Identities = 18/77 (23%), Positives = 37/77 (48%), Gaps = 6/77 (7%) Query: 246 RREEREREERLSRRSGSRTRDRRRSRSRDRRRRRSRSTSRERRKLSRSRSRDRHRRHRSR 305 ++EE++R + S S S + S S+ S S S + + +S+ R ++HR Sbjct: 184 KKEEKKRHKSSSSSSSSSSDSDSSSDSQ------SSSDSSDSESATEEKSKKRKKKHRKN 237 Query: 306 SRSHSRGHRRASRDRSA 322 SR H + ++ + + + Sbjct: 238 SRKHKKEKKKRKKSKKS 254 Score = 30.8 bits (68), Expect = 1.7 Identities = 19/92 (20%), Positives = 40/92 (43%), Gaps = 7/92 (7%) Query: 239 RNQDRLRR-------REEREREERLSRRSGSRTRDRRRSRSRDRRRRRSRSTSRERRKLS 291 R++DR RR R+E +R +R+ SG R +S + + + + RK++ Sbjct: 348 RSRDRFRRSETPPHWRQEMQRAQRMRVSSGERWIKGDKSELNEIKENQRSPVRVKERKIT 407 Query: 292 RSRSRDRHRRHRSRSRSHSRGHRRASRDRSAK 323 R+ ++ + H+ S++R + Sbjct: 408 DHRNVSESPNRKNEKEKKVKDHKSNSKERDIR 439 >gi|4826690 DEAH (Asp-Glu-Ala-His) box polypeptide 8 [Homo sapiens] Length = 1220 Score = 68.6 bits (166), Expect = 7e-12 Identities = 43/105 (40%), Positives = 56/105 (53%), Gaps = 8/105 (7%) Query: 221 IREKLDQLRKTVAEKQEKRNQDRLRRREEREREERLSRRSGSRTRDRRRSRSRDRRRRRS 280 ++ +D L++ A Q++ R E R+R ++ R SR+RDR R R RDR R R Sbjct: 139 VKVAVDVLKELEALMPSAAGQEKQRDAEHRDRTKKKKR---SRSRDRNRDRDRDRERNRD 195 Query: 281 RSTSRERRKLSRSRSRDRHR-----RHRSRSRSHSRGHRRASRDR 320 R R R SRSRSR R R R+RSRSRS S R RD+ Sbjct: 196 RDHKRRHRSRSRSRSRTRERNKVKSRYRSRSRSQSPPKDRKDRDK 240 Score = 48.5 bits (114), Expect = 8e-06 Identities = 31/88 (35%), Positives = 46/88 (52%), Gaps = 11/88 (12%) Query: 223 EKLDQLRKTVAEKQEKRNQDRLRRRE-----EREREERLSRRSGSRTRDRRRSRSRDRRR 277 E D+ +K + RN+DR R RE + +R R RS SRTR+R + +SR R R Sbjct: 166 EHRDRTKKKKRSRSRDRNRDRDRDRERNRDRDHKRRHRSRSRSRSRTRERNKVKSRYRSR 225 Query: 278 RRSRSTSRERRKLSR------SRSRDRH 299 RS+S ++R+ + R RD+H Sbjct: 226 SRSQSPPKDRKDRDKYGERNLDRWRDKH 253 >gi|239754909 PREDICTED: hypothetical protein [Homo sapiens] Length = 245 Score = 65.9 bits (159), Expect = 5e-11 Identities = 59/258 (22%), Positives = 111/258 (43%), Gaps = 30/258 (11%) Query: 52 TRMDLGECTKIHDLALRADY--EIASKERDLFFELDAMDHLESFIAECDRRTELAKKRLA 109 T + + C+ I + + EI +ER++ + ES E + +KR Sbjct: 15 TELQMVSCSHISKPCTQPGWQSEIREREREIETRKEGKKERES---ERKKERREREKRKR 71 Query: 110 ETQEEISAEVSAKAEKVHELNEEIGKLLAKAEQLGAEGNVDESQKILMEVEKVRAKKKEA 169 E ++E E K +K EE + + E+ EG EK + KKKE Sbjct: 72 EREKERKRERGKKEKKGERKKEERERKKRRREKENKEGE-----------EKEKRKKKEK 120 Query: 170 EEEYRNSMPASSFQQQKLRVCEVCSAYLGLHDNDRRLADHFGGKLHLGFIQIREKLDQLR 229 +E R S ++++ R E + +R+ + + + +E+ + R Sbjct: 121 KERGRTSKEGKERERKEERKREERK------ERERKKEEREKER------ERKERKKRER 168 Query: 230 KTVAEKQEKRNQDRLRRREEREREERLSRRSGSRTRDRRRSRSRDRRRRRSRSTSRERRK 289 K V EK+E+R + + R++RER + R R R RR R ++R+++ R R++ + Sbjct: 169 KQVGEKEEERKEKERKERKKRERNRK--ERKKERERKERRERKKERKKKEERKKERQKDR 226 Query: 290 LSRSRSRDRHRRHRSRSR 307 + R ++R +R R + Sbjct: 227 QTNWREKERGKRERKERK 244 Score = 55.1 bits (131), Expect = 8e-08 Identities = 27/105 (25%), Positives = 53/105 (50%), Gaps = 1/105 (0%) Query: 222 REKLDQLRKTVAEKQEKRNQDRLRRREEREREERLSRRSGSRTRDRRRSRSRDRRRRRSR 281 +EK + +K E++++R + + EE+E+ ++ ++ RT + R R R+R Sbjct: 84 KEKKGERKKEERERKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREE 143 Query: 282 STSRERRKLSRSRSRDR-HRRHRSRSRSHSRGHRRASRDRSAKYK 325 RER+K R + R+R R+ R R + + R ++R + K Sbjct: 144 RKERERKKEEREKERERKERKKRERKQVGEKEEERKEKERKERKK 188 Score = 52.0 bits (123), Expect = 7e-07 Identities = 29/104 (27%), Positives = 51/104 (49%), Gaps = 2/104 (1%) Query: 222 REKLDQLRKTVAEKQEKRNQDRLRRREEREREERLSRRSGSRTRDRRRSRSRDRRRRRSR 281 +EK + K + K ++R R+EER+REER R R++ R R ++R R + Sbjct: 112 KEKRKKKEKKERGRTSKEGKER-ERKEERKREERKERERKKEEREKERERKERKKRERKQ 170 Query: 282 STSRERRKLSRSRSRDRHRRHRSRSRSHSRGHRRASRDRSAKYK 325 +E + + R ++R +R R+R R+ R+R + K Sbjct: 171 VGEKEEERKEKER-KERKKRERNRKERKKERERKERRERKKERK 213 Score = 50.1 bits (118), Expect = 3e-06 Identities = 29/105 (27%), Positives = 51/105 (48%), Gaps = 3/105 (2%) Query: 222 REKLDQLRKTVAEKQEKRNQDRLRRREER-EREERLSRRSGSRTRDRRRSRSRDRRRRRS 280 +EK ++ R + K+ +R ++R +REER ERE + R R R R+ R R + + Sbjct: 118 KEKKERGRTSKEGKERERKEER--KREERKERERKKEEREKERERKERKKRERKQVGEKE 175 Query: 281 RSTSRERRKLSRSRSRDRHRRHRSRSRSHSRGHRRASRDRSAKYK 325 + RK + R R+R R + R R R ++ + + + K Sbjct: 176 EERKEKERKERKKRERNRKERKKERERKERRERKKERKKKEERKK 220 Score = 49.7 bits (117), Expect = 4e-06 Identities = 26/107 (24%), Positives = 51/107 (47%), Gaps = 4/107 (3%) Query: 220 QIREKLDQLRKTVAEKQEKRNQDRLRRREEREREERLSRRSGSRTRDRRRSRSRDRRRRR 279 +IRE+ R+ K+ K+ ++ R++E RERE+R R R R+R + + R++ Sbjct: 37 EIRERE---REIETRKEGKKERESERKKERREREKRKREREKERKRERGKKEKKGERKKE 93 Query: 280 SRSTSRERRKLSRSRSRDRHRRHRSRSRSHSRGHRRA-SRDRSAKYK 325 R + RR+ ++ +R + + R + R+R + K Sbjct: 94 ERERKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERK 140 Score = 48.1 bits (113), Expect = 1e-05 Identities = 28/130 (21%), Positives = 62/130 (47%), Gaps = 6/130 (4%) Query: 199 LHDNDRRLADHFGGKLHLGFIQIREKLD-QLRKTVAEKQEKRNQDRLRRREEREREERLS 257 + + +R + GK + +E+ + + RK EK+ KR + + ++ ER++EER Sbjct: 38 IREREREIETRKEGKKERESERKKERREREKRKREREKERKRERGKKEKKGERKKEER-E 96 Query: 258 RRSGSRTRDRRRSRSRDRRRRRSRS----TSRERRKLSRSRSRDRHRRHRSRSRSHSRGH 313 R+ R ++ + +++R+++ + TS+E ++ R R R R + R Sbjct: 97 RKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKERERKKEEREK 156 Query: 314 RRASRDRSAK 323 R ++R + Sbjct: 157 ERERKERKKR 166 Score = 44.7 bits (104), Expect = 1e-04 Identities = 23/109 (21%), Positives = 51/109 (46%), Gaps = 5/109 (4%) Query: 222 REKLDQLRKTVAEKQEKRNQDRLRRREEREREERLSRRSGSRTRDRRRSRSRDRRRRRSR 281 R+K ++ RK ++E + + +R+++E++ER + R+R+ R R+ R+ R R Sbjct: 90 RKKEERERKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKERER 149 Query: 282 -----STSRERRKLSRSRSRDRHRRHRSRSRSHSRGHRRASRDRSAKYK 325 RER++ + + + R + ++ R+R + K Sbjct: 150 KKEEREKERERKERKKRERKQVGEKEEERKEKERKERKKRERNRKERKK 198 Score = 43.5 bits (101), Expect = 3e-04 Identities = 24/106 (22%), Positives = 45/106 (42%), Gaps = 15/106 (14%) Query: 235 KQEKRNQDRLRRR--EEREREERLSRRSGSRTRDRRRSRSRDRRRRRSRSTSRERRKLSR 292 K+E+R +++ +R +ER+RE + G R ++ R + R R + +E+RK Sbjct: 60 KKERREREKRKREREKERKRERGKKEKKGERKKEERERKKRRREKENKEGEEKEKRKKKE 119 Query: 293 SRSRDR-------------HRRHRSRSRSHSRGHRRASRDRSAKYK 325 + R R +R + R + R R+R + K Sbjct: 120 KKERGRTSKEGKERERKEERKREERKERERKKEEREKERERKERKK 165 >gi|166235169 PRP38 pre-mRNA processing factor 38 (yeast) domain containing B [Homo sapiens] Length = 546 Score = 65.9 bits (159), Expect = 5e-11 Identities = 66/234 (28%), Positives = 104/234 (44%), Gaps = 10/234 (4%) Query: 100 RTELAKKRLAETQEEISAEVSAKAEKV--HELNEEIGKLLAKAEQLGAEGNVDESQKILM 157 R KK E EEI V + + L+ +++ EG+ S + Sbjct: 236 RPRKIKKDGKEGAEEIDRHVERRRSRSPRRSLSPRRSPRRSRSRSHHREGHGSSSFDREL 295 Query: 158 EVEKVRAK----KKEAEEEYRNSMPAS-SFQQQKLRVCEVCSAYLGLHDN--DRRLADHF 210 E EK R + KE E+E R S ++++ R E + D DRR D Sbjct: 296 EREKERQRLEREAKEREKERRRSRSIDRGLERRRSRSRERHRSRSRSRDRKGDRRDRDRE 355 Query: 211 GGKLHLGFIQIREKLDQLRKTVAEKQEKRNQDRLRRREER-EREERLSRRSGSRTRDRRR 269 K + + D+ R EK+ +R+++R + + R E EE+ + R R Sbjct: 356 REKENERGRRRDRDYDKERGNEREKERERSRERSKEQRSRGEVEEKKHKEDKDDRRHRDD 415 Query: 270 SRSRDRRRRRSRSTSRERRKLSRSRSRDRHRRHRSRSRSHSRGHRRASRDRSAK 323 R + ++ SRS SRER+ SRSRSR+ +R RSRS+ S H+ S+++S K Sbjct: 416 KRDSKKEKKHSRSRSRERKHRSRSRSRNAGKRSRSRSKEKSSKHKNESKEKSNK 469 Score = 64.7 bits (156), Expect = 1e-10 Identities = 64/264 (24%), Positives = 114/264 (43%), Gaps = 35/264 (13%) Query: 90 LESFIAECDRRTELAKKRLAETQEEISAEVSAKAEKVHELNEEIGKLLAKAEQLGAEGNV 149 L SF+ + + + L + Q+ I ++ + K+ + +E AE++ Sbjct: 204 LRSFLTKLEWFSTLFPRIPVPVQKNIDQQIKTRPRKIKKDGKE------GAEEIDRHVER 257 Query: 150 DESQKILMEVEKVRA-KKKEAEEEYRNSMPASSFQQQKLRVCEV--CSAYLGLHDNDRRL 206 S+ + R+ ++ + +R +SSF ++ R E + +RR Sbjct: 258 RRSRSPRRSLSPRRSPRRSRSRSHHREGHGSSSFDRELEREKERQRLEREAKEREKERRR 317 Query: 207 ADHFGGKLHLGFIQIREKLDQLRKTVAEKQEKRNQDRLRRREEREREERLSR-----RSG 261 + L + RE+ ++ K ++R++DR R +E ER R R R Sbjct: 318 SRSIDRGLERRRSRSRERHRSRSRSRDRKGDRRDRDR-EREKENERGRRRDRDYDKERGN 376 Query: 262 SRTRDRRRSRSR--------------------DRRRRRSRSTSRERRKLSRSRSRDRHRR 301 R ++R RSR R DRR R + S++ +K SRSRSR+R R Sbjct: 377 EREKERERSRERSKEQRSRGEVEEKKHKEDKDDRRHRDDKRDSKKEKKHSRSRSRERKHR 436 Query: 302 HRSRSRSHSRGHRRASRDRSAKYK 325 RSRSR+ + R S+++S+K+K Sbjct: 437 SRSRSRNAGKRSRSRSKEKSSKHK 460 Score = 56.6 bits (135), Expect = 3e-08 Identities = 37/114 (32%), Positives = 62/114 (54%), Gaps = 12/114 (10%) Query: 222 REKLDQLRKTVAEKQEKRNQDRLRRREEREREERLSRRSGSRTRDR---RRSRSRDRRRR 278 R D R + EK+ R++ R R+ R R +RS SR++++ ++ S+++ + Sbjct: 410 RRHRDDKRDSKKEKKHSRSRSRERKHRSRSRSRNAGKRSRSRSKEKSSKHKNESKEKSNK 469 Query: 279 RSRSTSRER-------RKLSRSRSRDRHR-RHRSRSRSHSRGHRRASRDRSAKY 324 RSRS S+ R +K S S+++ R R RS+ RSH R H S+D+S K+ Sbjct: 470 RSRSGSQGRTDSVEKSKKREHSPSKEKSRKRSRSKERSHKRDH-SDSKDQSDKH 522 Score = 55.1 bits (131), Expect = 8e-08 Identities = 33/95 (34%), Positives = 52/95 (54%), Gaps = 9/95 (9%) Query: 222 REKLDQLRKTVAEKQEKRNQDRLRRREEREREERLSRRSGSRTRDRRRSRSRDRRRRRSR 281 R K + R V EK+ K ++D R R+++ R + + RSRSR+ R+ RSR Sbjct: 388 RSKEQRSRGEVEEKKHKEDKDDRRHRDDK--------RDSKKEKKHSRSRSRE-RKHRSR 438 Query: 282 STSRERRKLSRSRSRDRHRRHRSRSRSHSRGHRRA 316 S SR K SRSRS+++ +H++ S+ S R+ Sbjct: 439 SRSRNAGKRSRSRSKEKSSKHKNESKEKSNKRSRS 473 Score = 45.4 bits (106), Expect = 7e-05 Identities = 46/210 (21%), Positives = 89/210 (42%), Gaps = 34/210 (16%) Query: 98 DRRTELAKKRLAETQEEISAEVSAKAEKVHELNEEIGKLLAKAEQLGAEGNVDESQ-KIL 156 DR E +R + E + EK E + E ++++ + G V+E + K Sbjct: 353 DREREKENERGRRRDRDYDKERGNEREKERERSRE------RSKEQRSRGEVEEKKHKED 406 Query: 157 MEVEKVRAKKKEAEEEYRNSMPASSFQQQKLRVCEVCSAYLGLHDNDRRLADHFGGKLHL 216 + + R K+++++E ++S S ++ + R S G R Sbjct: 407 KDDRRHRDDKRDSKKEKKHSRSRSRERKHRSRSR---SRNAGKRSRSRS----------- 452 Query: 217 GFIQIREKLDQLRKTVAEKQEKRNQDRLRRREEREREERLSRRSGSRTRDRRRSRSRDRR 276 +EK + + EK KR++ + R + + + S S+ + R+RSRS++R Sbjct: 453 -----KEKSSKHKNESKEKSNKRSRSGSQGRTDSVEKSKKREHSPSKEKSRKRSRSKERS 507 Query: 277 RRRSRSTSRERRKLSRSRSRDRHRRHRSRS 306 +R S S+++ D+H R RS+S Sbjct: 508 HKRDHSDSKDQS--------DKHDRRRSQS 529 Score = 38.5 bits (88), Expect = 0.008 Identities = 53/223 (23%), Positives = 95/223 (42%), Gaps = 25/223 (11%) Query: 98 DRRTELAKKRLAETQEEISAEVSAKAEKVHELNEEIGKLLAKAEQLGAEGNVDESQKILM 157 DR E + R E S K ++ E K + G + D ++ Sbjct: 322 DRGLERRRSRSRERHRSRSRSRDRKGDRRDRDRER-----EKENERGRRRDRDYDKERGN 376 Query: 158 EVEKVRAKKKEAEEEYRNSMPASSFQQQKLRVCEVCSAYLGLHDNDRRLADHFGGKLHLG 217 E EK R + +E +E R+ + ++ + H +D+R D K H Sbjct: 377 EREKERERSRERSKEQRSRGEVEEKKHKEDKDDR-------RHRDDKR--DSKKEKKH-S 426 Query: 218 FIQIREKLDQLR---KTVAEKQEKRNQDRLRRREEREREERLSR-RSGSRTRDRRRSRSR 273 + RE+ + R + ++ R++++ + + +E+ R RSGS + R+ S Sbjct: 427 RSRSRERKHRSRSRSRNAGKRSRSRSKEKSSKHKNESKEKSNKRSRSGS----QGRTDSV 482 Query: 274 DRRRRRSRSTSRER-RKLSRSRSRDRHRRHRSRSRSHSRGHRR 315 ++ ++R S S+E+ RK SRS+ R H+R S S+ S H R Sbjct: 483 EKSKKREHSPSKEKSRKRSRSKERS-HKRDHSDSKDQSDKHDR 524 >gi|55741709 RNA binding motif protein 25 [Homo sapiens] Length = 843 Score = 64.7 bits (156), Expect = 1e-10 Identities = 55/178 (30%), Positives = 82/178 (46%), Gaps = 22/178 (12%) Query: 163 RAKKKEAEEEYRNSMPASSFQQQKLRVCEVCSAYLGLHDNDRRLADHFGGKL---HLGFI 219 R KKKE +E+ P + L E +A + + ++ R L K H Sbjct: 234 RKKKKEKKEDIFRRFPVAPLIPYPLITKEDINA-IEMEEDKRDLISREISKFRDTHKKLE 292 Query: 220 QIREKLDQLRKTVAEKQEKRNQDRLRRREEREREERLSR-----------RSGSRTRDRR 268 + + K ++ R+ + +++ +R ++R R RE RERE R R R RDR Sbjct: 293 EEKGKKEKERQEIEKERRERERERERERERREREREREREREREKEKERERERERDRDRD 352 Query: 269 RSRSRDRRRRRSRSTSRERRKLS-----RSRSRDRHR-RHRSRSRSHSRGHRRASRDR 320 R++ RDR R R R R+R + S RSRSR++ R R R R R R R R+R Sbjct: 353 RTKERDRDRDRERDRDRDRERSSDRNKDRSRSREKSRDRERERERERER-ERERERER 409 Score = 63.9 bits (154), Expect = 2e-10 Identities = 65/259 (25%), Positives = 107/259 (41%), Gaps = 25/259 (9%) Query: 88 DHLESFIAECDRRTELAKKRLAETQEEISAEVSAKAE--------KVHELNEEIGK---- 135 D E+ E RR ++ K + E S+E++A ++ K E E+I + Sbjct: 191 DDEEALDEETKRRDQMIKGAIEVLIREYSSELNAPSQESDSHPRKKKKEKKEDIFRRFPV 250 Query: 136 -------LLAKAEQLGAEGNVDESQKILMEVEKVRAKKKEAEEEYRNSMPASSFQQQKLR 188 L+ K + E D+ I E+ K R K+ EEE +++ R Sbjct: 251 APLIPYPLITKEDINAIEMEEDKRDLISREISKFRDTHKKLEEEKGKKEKERQEIEKERR 310 Query: 189 VCEVCSAYLGLHDNDRRLADHFGGKLHLGFIQIREKLDQLRKTVAEKQEKRNQDRLRRRE 248 E + +RR + + + + ++ R ++ ++R++DR R R+ Sbjct: 311 ERERERE----RERERREREREREREREREKEKERERERERDRDRDRTKERDRDRDRERD 366 Query: 249 EREREERLSRRSGSRTRDRRRSRSRDRRRRRSRSTSRER-RKLSRSRSRDRHR-RHRSRS 306 ER S R+ R+R R +SR R+R R R R RER R+ R R R+R R R R R Sbjct: 367 RDRDRERSSDRNKDRSRSREKSRDRERERERERERERERERERERERERERERERERERE 426 Query: 307 RSHSRGHRRASRDRSAKYK 325 + R D + K Sbjct: 427 KDKKRDREEDEEDAYERRK 445 Score = 60.5 bits (145), Expect = 2e-09 Identities = 55/219 (25%), Positives = 95/219 (43%), Gaps = 29/219 (13%) Query: 111 TQEEISAEVSAKAEKVHELNEEIGKLLAKAEQLGAEGNVDESQKILMEVEKVRAKKKEAE 170 T+E+I+A + + +K ++ EI K ++L E E ++ +E E+ R +++E E Sbjct: 260 TKEDINA-IEMEEDKRDLISREISKFRDTHKKLEEEKGKKEKERQEIEKER-RERERERE 317 Query: 171 EEYRNSMPASSFQQQKLRVCEVCSAYLGLHDNDRRLADHFGGKLHLGFIQIREKLDQLRK 230 E ++++ R E D DR D+ ++ Sbjct: 318 RERERREREREREREREREKEKERERERERDRDR---------------------DRTKE 356 Query: 231 TVAEKQEKRNQDRLRRREEREREERLSRRSGSRTRDRRRSRSRDRRRRRSRSTSRER-RK 289 ++ +R++DR R R ++R RS ++RDR R R R+R R R R RER R+ Sbjct: 357 RDRDRDRERDRDRDRERSSDRNKDR--SRSREKSRDRERERERERERERERERERERERE 414 Query: 290 LSRSRSRDRHR---RHRSRSRSHSRGHRRASRDRSAKYK 325 R R R+R R + R R + R +R + K Sbjct: 415 REREREREREREKDKKRDREEDEEDAYERRKLERKLREK 453 Score = 45.8 bits (107), Expect = 5e-05 Identities = 53/223 (23%), Positives = 98/223 (43%), Gaps = 33/223 (14%) Query: 110 ETQEEISAEVSAKAEKVHELNEEIGKLLAKAEQLGAEGNVDESQKILMEVEKVRAKKKEA 169 + ++ IS E+S + +L EE GK + +++ E E ++ E E+ R +++ Sbjct: 272 DKRDLISREISKFRDTHKKLEEEKGKKEKERQEIEKERRERERER---ERERERRERERE 328 Query: 170 EEEYRNSMPASSFQQQKLRVCEVCSAYLGLHDNDR---------RLADHFGGKLHLGFIQ 220 E R ++++ R + D DR R +D + + Sbjct: 329 REREREREKEKERERERERDRDRDRTKERDRDRDRERDRDRDRERSSDRNKDRS-----R 383 Query: 221 IREKL-DQLRKTVAEKQEKRNQDRLRRRE---EREREERLSRRSGSRTRDRRRSRSRDRR 276 REK D+ R+ E++ +R ++R R RE ERERE R+R R + + R Sbjct: 384 SREKSRDRERERERERERERERERERERERERERERE-----------REREREKDKKRD 432 Query: 277 RRRSRSTSRERRKLSRSRSRDRHRRHRSRSRSHSRGHRRASRD 319 R + ERRKL R + R++ ++ R ++ R+ +R+ Sbjct: 433 REEDEEDAYERRKLER-KLREKEAAYQERLKNWEIRERKKTRE 474 Score = 34.3 bits (77), Expect = 0.16 Identities = 46/214 (21%), Positives = 83/214 (38%), Gaps = 29/214 (13%) Query: 96 ECDRRTELAKKRLAETQEEISAEVSAKAEKVHELNEEIGKLLAKAEQLGAEGNVDESQKI 155 E +R E ++R E + E E ++ E +EE K E+ E +++ Sbjct: 402 EREREREREREREREREREREREREKDKKRDREEDEEDAYERRKLERKLREKEAAYQERL 461 Query: 156 ----LMEVEKVRAKKKEAEEEYRNSMPASSFQQQKLRVCEVCSAYLGLHDNDRRLADHFG 211 + E +K R +KEAE E +++ + + +L +D+DR ++ Sbjct: 462 KNWEIRERKKTREYEKEAEREEER-------RREMAKEAKRLKEFLEDYDDDRDDPKYYR 514 Query: 212 GKLHLGFIQIREKLDQLRKTVAEKQEKRNQDRLRRREERE--REERLSRRSGSRTRDRRR 269 G ++ REK + E +DR R +EE E R+ L+ + +R Sbjct: 515 GSALQKRLRDREK----------EMEADERDRKREKEELEEIRQRLLAEGHPDPDAELQR 564 Query: 270 SRSRDRRRRRSR------STSRERRKLSRSRSRD 297 RRR+ + S E K + R+ Sbjct: 565 MEQEAERRRQPQIKQEPESEEEEEEKQEKEEKRE 598 Score = 31.6 bits (70), Expect = 1.0 Identities = 27/112 (24%), Positives = 45/112 (40%), Gaps = 26/112 (23%) Query: 227 QLRKTVAEKQEKRNQDRLRRREEREREE-RLSRRSGSRTRDRRRSRSRDRRR-------- 277 +L + + EK E Q+RL+ E RER++ R + R +RRR +++ +R Sbjct: 445 KLERKLREK-EAAYQERLKNWEIRERKKTREYEKEAEREEERRREMAKEAKRLKEFLEDY 503 Query: 278 ----------------RRSRSTSRERRKLSRSRSRDRHRRHRSRSRSHSRGH 313 +R R +E R R R++ R R + GH Sbjct: 504 DDDRDDPKYYRGSALQKRLRDREKEMEADERDRKREKEELEEIRQRLLAEGH 555 Score = 28.9 bits (63), Expect = 6.5 Identities = 20/99 (20%), Positives = 44/99 (44%), Gaps = 8/99 (8%) Query: 100 RTELAKKRLAETQEEISAEVSAKAEKVHELNEEIGKLLAKA--------EQLGAEGNVDE 151 R +KRL + ++E+ A+ + + EL E +LLA+ +++ E Sbjct: 514 RGSALQKRLRDREKEMEADERDRKREKEELEEIRQRLLAEGHPDPDAELQRMEQEAERRR 573 Query: 152 SQKILMEVEKVRAKKKEAEEEYRNSMPASSFQQQKLRVC 190 +I E E ++++ E+E + P ++ + + C Sbjct: 574 QPQIKQEPESEEEEEEKQEKEEKREEPMEEEEEPEQKPC 612 >gi|239749449 PREDICTED: hypothetical protein [Homo sapiens] Length = 275 Score = 64.7 bits (156), Expect = 1e-10 Identities = 33/102 (32%), Positives = 59/102 (57%), Gaps = 3/102 (2%) Query: 222 REKLDQLRKTVAEKQEKRNQDRLRRREEREREERLSRRSGSRTRDRRRSRSRDRRRRRSR 281 REK + RK +K+E++ + R R++++ER+ER R + R+R+R + R ++RR+ R Sbjct: 90 REKERRKRKKEKKKRERKQRGRRERKKKKERKER--ERENKQRRERKRKKRRKKKRRKER 147 Query: 282 STSRERRKLSRSRSRDRHRRHRSRSRSHSRGHRRASRDRSAK 323 +ER K R R + R + R + R +R R+ R+R + Sbjct: 148 KREKERGKRERKRKK-RKKEEREKKRERNRKERKKERERKER 188 Score = 58.9 bits (141), Expect = 6e-09 Identities = 28/105 (26%), Positives = 56/105 (53%), Gaps = 3/105 (2%) Query: 222 REKLDQLRKTVAEKQEKRNQDRLRRREEREREERLSRRSGSRTRDRRRSRSRDRRRRRSR 281 +EK + ++ +++E++ ++R ++R+ER +ER R+ + R+R++ R+R++++ R Sbjct: 61 KEKKKRKKRERGKERERKRKEREKQRKERREKERRKRKKEKKKRERKQRGRRERKKKKER 120 Query: 282 STSRERRKLSRSRSRDRHR---RHRSRSRSHSRGHRRASRDRSAK 323 K R R R + R R + R R RG R R + K Sbjct: 121 KERERENKQRRERKRKKRRKKKRRKERKREKERGKRERKRKKRKK 165 Score = 57.8 bits (138), Expect = 1e-08 Identities = 28/105 (26%), Positives = 55/105 (52%), Gaps = 1/105 (0%) Query: 222 REKLDQLRKTVAEKQEKRNQDRLRRREEREREERLSRRSGSRTRDRRRSRSRDRRRRRSR 281 RE+ + R+ E++ +R + ++R++RER + R+ R + R+ R ++RR+R+ Sbjct: 41 REREKRKREREKERKRERGKKEKKKRKKRERGKERERKRKEREKQRKERREKERRKRKKE 100 Query: 282 STSRERRKLS-RSRSRDRHRRHRSRSRSHSRGHRRASRDRSAKYK 325 RER++ R R + + R+ R R R +R R + + K Sbjct: 101 KKKRERKQRGRRERKKKKERKERERENKQRRERKRKKRRKKKRRK 145 Score = 56.6 bits (135), Expect = 3e-08 Identities = 45/232 (19%), Positives = 92/232 (39%), Gaps = 34/232 (14%) Query: 94 IAECDRRTELAKKRLAETQEEISAEVSAKAEKVHELNEEIGKLLAKAEQLGAEGNVDESQ 153 + C ++ +R +E ++E K E+ E E GK K + G E + Sbjct: 19 MVSCSHISKPCTQRESERKKERREREKRKREREKERKRERGKKEKKKRKKRERGKERERK 78 Query: 154 KILMEVEKVRAKKKEAEEEYRNSMPASSFQQQKLRVCEVCSAYLGLHDNDRRLADHFGGK 213 + E EK R +++E E R ++Q+ Sbjct: 79 R--KEREKQRKERREKERRKRKKEKKKRERKQR--------------------------- 109 Query: 214 LHLGFIQIREKLDQLRKTVAEKQEKRNQDRLRRREEREREERLSRRSGSRTRDR--RRSR 271 G + ++K ++ + KQ + + + RR+++R +E + + G R R R R+ Sbjct: 110 ---GRRERKKKKERKERERENKQRRERKRKKRRKKKRRKERKREKERGKRERKRKKRKKE 166 Query: 272 SRDRRRRRSRSTSRERRKLSRSRSRDRHRRHRSRSRSHSRGHRRASRDRSAK 323 R+++R R+R ++ R+ R R + R+ R + + R+ R ++ Sbjct: 167 EREKKRERNRKERKKERERKERRERKKERKKERRKKKERKKDRKTDRQTDSQ 218 Score = 50.4 bits (119), Expect = 2e-06 Identities = 22/94 (23%), Positives = 48/94 (51%), Gaps = 3/94 (3%) Query: 235 KQEKRNQDRLRRREEREREERLSRRSGSRTRDRRRSRSRDRRRR---RSRSTSRERRKLS 291 K+E+R +++ +R E+ER+ ++ + + R R + R+R+R+ + R RE+ + Sbjct: 37 KKERREREKRKREREKERKRERGKKEKKKRKKRERGKERERKRKEREKQRKERREKERRK 96 Query: 292 RSRSRDRHRRHRSRSRSHSRGHRRASRDRSAKYK 325 R + + + R + R + R R+R K + Sbjct: 97 RKKEKKKRERKQRGRRERKKKKERKERERENKQR 130 Score = 43.5 bits (101), Expect = 3e-04 Identities = 20/80 (25%), Positives = 39/80 (48%), Gaps = 1/80 (1%) Query: 246 RREEREREERLSRRSGSRTRDRRRSRSRDRRRRRSRSTSRERRKLSRSRSRDRHRRHRSR 305 +RE ++ER R R R++ R R R ++ ++ R RER K + ++R ++ + R Sbjct: 31 QRESERKKERREREKRKREREKERKRERGKKEKKKRK-KRERGKERERKRKEREKQRKER 89 Query: 306 SRSHSRGHRRASRDRSAKYK 325 R ++ + R K + Sbjct: 90 REKERRKRKKEKKKRERKQR 109 Score = 41.2 bits (95), Expect = 0.001 Identities = 48/202 (23%), Positives = 81/202 (40%), Gaps = 7/202 (3%) Query: 96 ECDRRTELAK--KRLAETQEEISAEVSAKAEKVHELNEEIGKLLAKAEQLGAEGNVDESQ 153 E +R+ E + KR E ++E E K EK E GK + E+ E + Sbjct: 33 ESERKKERREREKRKREREKERKRE-RGKKEKKKRKKRERGK---ERERKRKEREKQRKE 88 Query: 154 KILMEVEKVRAKKKEAEEEYRNSMPASSFQQQKLRVCEVCSAYLGLHDNDRRLADHFGGK 213 + E K + +KK+ E + R +++K R E R+ K Sbjct: 89 RREKERRKRKKEKKKRERKQRGRRERKKKKERKERERENKQRRERKRKKRRKKKRRKERK 148 Query: 214 LHLGFIQIREKLDQLRKTVAEKQEKRNQ-DRLRRREEREREERLSRRSGSRTRDRRRSRS 272 + K + +K EK+ +RN+ +R + RE +ER ER R R + + R + Sbjct: 149 REKERGKRERKRKKRKKEEREKKRERNRKERKKERERKERRERKKERKKERRKKKERKKD 208 Query: 273 RDRRRRRSRSTSRERRKLSRSR 294 R R+ R R+ + +R Sbjct: 209 RKTDRQTDSQVFRPLRESAFNR 230 >gi|21040326 SON DNA-binding protein isoform F [Homo sapiens] Length = 2426 Score = 64.7 bits (156), Expect = 1e-10 Identities = 38/94 (40%), Positives = 53/94 (56%), Gaps = 2/94 (2%) Query: 230 KTVAEKQEKRNQDRLRRREEREREERLSRRSGSRTRDRR--RSRSRDRRRRRSRSTSRER 287 K+ + R++ R RRR R R + RRS S+ + +R + RS+ R R+R RS+SR+ Sbjct: 1855 KSHRSQTRSRSRSRRRRRSSRSRSKSRGRRSVSKEKRKRSPKHRSKSRERKRKRSSSRDN 1914 Query: 288 RKLSRSRSRDRHRRHRSRSRSHSRGHRRASRDRS 321 RK R+RSR RR RS + S R R R RS Sbjct: 1915 RKTVRARSRTPSRRSRSHTPSRRRRSRSVGRRRS 1948 Score = 64.3 bits (155), Expect = 1e-10 Identities = 43/99 (43%), Positives = 60/99 (60%), Gaps = 9/99 (9%) Query: 235 KQEKRNQDRLRRREEREREERLSRRS----GSRTRDRRR-SRSRDRRRRRSRSTSRERRK 289 ++ K+N++R + +E++R+ L RS S + R+R S SR R R+RS S S+ R Sbjct: 1801 EKSKKNKNRDKGEKEKKRDSSLRSRSKRSKSSEHKSRKRTSESRSRARKRS-SKSKSHRS 1859 Query: 290 LSRSRSRDRHRRHRSRSRSHSRGHRRAS---RDRSAKYK 325 +RSRSR R RR SRSRS SRG R S R RS K++ Sbjct: 1860 QTRSRSRSRRRRRSSRSRSKSRGRRSVSKEKRKRSPKHR 1898 Score = 63.2 bits (152), Expect = 3e-10 Identities = 42/115 (36%), Positives = 62/115 (53%), Gaps = 9/115 (7%) Query: 218 FIQIREKLDQLRKTV----AEKQEKRNQDRLRRREEREREERLSRRSGSRTRDRRRSRS- 272 F+++++ ++ +K EK++KR+ R + + E SR+ S +R R R RS Sbjct: 1793 FVKVKDTHEKSKKNKNRDKGEKEKKRDSSLRSRSKRSKSSEHKSRKRTSESRSRARKRSS 1852 Query: 273 ---RDRRRRRSRSTSRERRKLSRSRSRDRHRRHRSR-SRSHSRGHRRASRDRSAK 323 R + RSRS SR RR+ SRSRS+ R RR S+ R S HR SR+R K Sbjct: 1853 KSKSHRSQTRSRSRSRRRRRSSRSRSKSRGRRSVSKEKRKRSPKHRSKSRERKRK 1907 Score = 59.3 bits (142), Expect = 4e-09 Identities = 42/108 (38%), Positives = 58/108 (53%), Gaps = 9/108 (8%) Query: 222 REKLDQLRKTVAEKQEKRNQDRLRRREEREREERLSRRSGSRTRDRRRSRSRDRRRR--- 278 +++ LR + ++ R R E R R + S +S S R + RSRSR RRRR Sbjct: 1816 KKRDSSLRSRSKRSKSSEHKSRKRTSESRSRARKRSSKSKSH-RSQTRSRSRSRRRRRSS 1874 Query: 279 RSRSTSRERRKLSRSRSR--DRHR---RHRSRSRSHSRGHRRASRDRS 321 RSRS SR RR +S+ + + +HR R R R RS SR +R+ R RS Sbjct: 1875 RSRSKSRGRRSVSKEKRKRSPKHRSKSRERKRKRSSSRDNRKTVRARS 1922 Score = 57.4 bits (137), Expect = 2e-08 Identities = 48/113 (42%), Positives = 60/113 (53%), Gaps = 12/113 (10%) Query: 222 REKLDQLRKTVAEKQEKRNQDRLRRREEREREERLSRRSGSRTRD-RRRSRSRDRRR--- 277 R++ + R E++ KR+ R R+ R R SRRS S T RRRSRS RRR Sbjct: 1891 RKRSPKHRSKSRERKRKRSSSRDNRKTVRARSRTPSRRSRSHTPSRRRRSRSVGRRRSFS 1950 Query: 278 ----RRSRSTSRERRKLSRSRSRDRHRRHRS---RSRSHSRGHRRASRDRSAK 323 RRSR+ SR R SR RSR RR R+ RSR+ SR R SR R ++ Sbjct: 1951 ISPSRRSRTPSRRSRTPSR-RSRTPSRRSRTPSRRSRTPSRRSRTPSRRRRSR 2002 Score = 42.7 bits (99), Expect = 4e-04 Identities = 34/87 (39%), Positives = 44/87 (50%), Gaps = 9/87 (10%) Query: 236 QEKRNQDRLRRREEREREERLSRRSGSRTRDRRRS-RSRDR---RRRRSRSTSRERRKLS 291 +EKR + R + RER +R S +RD R++ R+R R RR RS + SR RR S Sbjct: 1888 KEKRKRSPKHRSKSRER-----KRKRSSSRDNRKTVRARSRTPSRRSRSHTPSRRRRSRS 1942 Query: 292 RSRSRDRHRRHRSRSRSHSRGHRRASR 318 R R RSR+ SR R SR Sbjct: 1943 VGRRRSFSISPSRRSRTPSRRSRTPSR 1969 Score = 40.8 bits (94), Expect = 0.002 Identities = 42/117 (35%), Positives = 48/117 (41%), Gaps = 9/117 (7%) Query: 204 RRLADHFGGKLHLGFIQIREKLDQLRKTVAEKQEKRNQDRLRRREEREREERLSRRSGSR 263 RR + G + R R++ + R R R R R SRRS R Sbjct: 1937 RRRSRSVGRRRSFSISPSRRSRTPSRRSRTPSRRSRTPSR-RSRTPSRRSRTPSRRS--R 1993 Query: 264 TRDRRRSRSRDRRRRRSRSTS-----RERRKLSRSRSRDRHRRHRSRSRSHSRGHRR 315 T RRR RSR RRRS S S R R L R SR RR RSRS R +R Sbjct: 1994 TPSRRR-RSRSVVRRRSFSISPVRLRRSRTPLRRRFSRSPIRRKRSRSSERGRSPKR 2049 Score = 40.4 bits (93), Expect = 0.002 Identities = 39/104 (37%), Positives = 49/104 (47%), Gaps = 10/104 (9%) Query: 229 RKTVAEKQEKRNQDRLRRREEREREERL-SRRSGSRTRDRRRSRSRDR---RRRRSRSTS 284 R++ + +R++ RR R R SRRS + +R R R R RRRRSRS Sbjct: 1946 RRSFSISPSRRSRTPSRRSRTPSRRSRTPSRRSRTPSRRSRTPSRRSRTPSRRRRSRSVV 2005 Query: 285 RERRKLSRS-----RSRDRHRRHRSRSRSHSRGHRRASRDRSAK 323 R RR S S RSR RR SRS + R + R RS K Sbjct: 2006 R-RRSFSISPVRLRRSRTPLRRRFSRSPIRRKRSRSSERGRSPK 2048 >gi|21040314 SON DNA-binding protein isoform B [Homo sapiens] Length = 2303 Score = 64.7 bits (156), Expect = 1e-10 Identities = 38/94 (40%), Positives = 53/94 (56%), Gaps = 2/94 (2%) Query: 230 KTVAEKQEKRNQDRLRRREEREREERLSRRSGSRTRDRR--RSRSRDRRRRRSRSTSRER 287 K+ + R++ R RRR R R + RRS S+ + +R + RS+ R R+R RS+SR+ Sbjct: 1855 KSHRSQTRSRSRSRRRRRSSRSRSKSRGRRSVSKEKRKRSPKHRSKSRERKRKRSSSRDN 1914 Query: 288 RKLSRSRSRDRHRRHRSRSRSHSRGHRRASRDRS 321 RK R+RSR RR RS + S R R R RS Sbjct: 1915 RKTVRARSRTPSRRSRSHTPSRRRRSRSVGRRRS 1948 Score = 64.3 bits (155), Expect = 1e-10 Identities = 43/99 (43%), Positives = 60/99 (60%), Gaps = 9/99 (9%) Query: 235 KQEKRNQDRLRRREEREREERLSRRS----GSRTRDRRR-SRSRDRRRRRSRSTSRERRK 289 ++ K+N++R + +E++R+ L RS S + R+R S SR R R+RS S S+ R Sbjct: 1801 EKSKKNKNRDKGEKEKKRDSSLRSRSKRSKSSEHKSRKRTSESRSRARKRS-SKSKSHRS 1859 Query: 290 LSRSRSRDRHRRHRSRSRSHSRGHRRAS---RDRSAKYK 325 +RSRSR R RR SRSRS SRG R S R RS K++ Sbjct: 1860 QTRSRSRSRRRRRSSRSRSKSRGRRSVSKEKRKRSPKHR 1898 Score = 63.2 bits (152), Expect = 3e-10 Identities = 42/115 (36%), Positives = 62/115 (53%), Gaps = 9/115 (7%) Query: 218 FIQIREKLDQLRKTV----AEKQEKRNQDRLRRREEREREERLSRRSGSRTRDRRRSRS- 272 F+++++ ++ +K EK++KR+ R + + E SR+ S +R R R RS Sbjct: 1793 FVKVKDTHEKSKKNKNRDKGEKEKKRDSSLRSRSKRSKSSEHKSRKRTSESRSRARKRSS 1852 Query: 273 ---RDRRRRRSRSTSRERRKLSRSRSRDRHRRHRSR-SRSHSRGHRRASRDRSAK 323 R + RSRS SR RR+ SRSRS+ R RR S+ R S HR SR+R K Sbjct: 1853 KSKSHRSQTRSRSRSRRRRRSSRSRSKSRGRRSVSKEKRKRSPKHRSKSRERKRK 1907 Score = 59.3 bits (142), Expect = 4e-09 Identities = 42/108 (38%), Positives = 58/108 (53%), Gaps = 9/108 (8%) Query: 222 REKLDQLRKTVAEKQEKRNQDRLRRREEREREERLSRRSGSRTRDRRRSRSRDRRRR--- 278 +++ LR + ++ R R E R R + S +S S R + RSRSR RRRR Sbjct: 1816 KKRDSSLRSRSKRSKSSEHKSRKRTSESRSRARKRSSKSKSH-RSQTRSRSRSRRRRRSS 1874 Query: 279 RSRSTSRERRKLSRSRSR--DRHR---RHRSRSRSHSRGHRRASRDRS 321 RSRS SR RR +S+ + + +HR R R R RS SR +R+ R RS Sbjct: 1875 RSRSKSRGRRSVSKEKRKRSPKHRSKSRERKRKRSSSRDNRKTVRARS 1922 Score = 57.4 bits (137), Expect = 2e-08 Identities = 48/113 (42%), Positives = 60/113 (53%), Gaps = 12/113 (10%) Query: 222 REKLDQLRKTVAEKQEKRNQDRLRRREEREREERLSRRSGSRTRD-RRRSRSRDRRR--- 277 R++ + R E++ KR+ R R+ R R SRRS S T RRRSRS RRR Sbjct: 1891 RKRSPKHRSKSRERKRKRSSSRDNRKTVRARSRTPSRRSRSHTPSRRRRSRSVGRRRSFS 1950 Query: 278 ----RRSRSTSRERRKLSRSRSRDRHRRHRS---RSRSHSRGHRRASRDRSAK 323 RRSR+ SR R SR RSR RR R+ RSR+ SR R SR R ++ Sbjct: 1951 ISPSRRSRTPSRRSRTPSR-RSRTPSRRSRTPSRRSRTPSRRSRTPSRRRRSR 2002 Score = 42.7 bits (99), Expect = 4e-04 Identities = 34/87 (39%), Positives = 44/87 (50%), Gaps = 9/87 (10%) Query: 236 QEKRNQDRLRRREEREREERLSRRSGSRTRDRRRS-RSRDR---RRRRSRSTSRERRKLS 291 +EKR + R + RER +R S +RD R++ R+R R RR RS + SR RR S Sbjct: 1888 KEKRKRSPKHRSKSRER-----KRKRSSSRDNRKTVRARSRTPSRRSRSHTPSRRRRSRS 1942 Query: 292 RSRSRDRHRRHRSRSRSHSRGHRRASR 318 R R RSR+ SR R SR Sbjct: 1943 VGRRRSFSISPSRRSRTPSRRSRTPSR 1969 Score = 40.8 bits (94), Expect = 0.002 Identities = 42/117 (35%), Positives = 48/117 (41%), Gaps = 9/117 (7%) Query: 204 RRLADHFGGKLHLGFIQIREKLDQLRKTVAEKQEKRNQDRLRRREEREREERLSRRSGSR 263 RR + G + R R++ + R R R R R SRRS R Sbjct: 1937 RRRSRSVGRRRSFSISPSRRSRTPSRRSRTPSRRSRTPSR-RSRTPSRRSRTPSRRS--R 1993 Query: 264 TRDRRRSRSRDRRRRRSRSTS-----RERRKLSRSRSRDRHRRHRSRSRSHSRGHRR 315 T RRR RSR RRRS S S R R L R SR RR RSRS R +R Sbjct: 1994 TPSRRR-RSRSVVRRRSFSISPVRLRRSRTPLRRRFSRSPIRRKRSRSSERGRSPKR 2049 Score = 40.4 bits (93), Expect = 0.002 Identities = 39/104 (37%), Positives = 49/104 (47%), Gaps = 10/104 (9%) Query: 229 RKTVAEKQEKRNQDRLRRREEREREERL-SRRSGSRTRDRRRSRSRDR---RRRRSRSTS 284 R++ + +R++ RR R R SRRS + +R R R R RRRRSRS Sbjct: 1946 RRSFSISPSRRSRTPSRRSRTPSRRSRTPSRRSRTPSRRSRTPSRRSRTPSRRRRSRSVV 2005 Query: 285 RERRKLSRS-----RSRDRHRRHRSRSRSHSRGHRRASRDRSAK 323 R RR S S RSR RR SRS + R + R RS K Sbjct: 2006 R-RRSFSISPVRLRRSRTPLRRRFSRSPIRRKRSRSSERGRSPK 2048 >gi|239747134 PREDICTED: hypothetical protein XP_002343921 [Homo sapiens] Length = 600 Score = 63.9 bits (154), Expect = 2e-10 Identities = 60/231 (25%), Positives = 101/231 (43%), Gaps = 17/231 (7%) Query: 96 ECDRRTELAKKRLAETQEEISAEVSAKAEKVHELNEEIGKLLAKAEQLGAEGNVDESQKI 155 E +R E + R + Q E + A+ E+ + + E + + Q E + ++ Sbjct: 130 ETEREGERGRDRQTDGQRERERQRDAEKERERQTDRERQRQTERNRQKEREREKNRQERR 189 Query: 156 LMEVEKVRAKKKEAEEEYRNSMPASSFQQQKLRVCEVCSAYLGLHDNDRRLADHFGGKLH 215 E+ R ++KE + E R+S ++++ E + DR+ + Sbjct: 190 ----ERERQREKENKTEDRHSERGRERERERETETETERKRQTDRERDRQRKTEREREKQ 245 Query: 216 LGFIQIREKLDQLRKTVAEKQEKRNQDRLRRREEREREERLSRRSGSRTRDRRRSRSRDR 275 RE+ + R+T +K+ +R +DR R R+ R++E R R R RR R R+ Sbjct: 246 AE----RERASE-RETERDKERERERDRDRDRDRRQKERE---RQTDRKRQRRTERDRET 297 Query: 276 RRRRSRSTSRERRKLSRSRSRDRHR---RHRSRSRSHSRGHRRASRDRSAK 323 R+R R RER + R+R R+R R R R R R R R R+R K Sbjct: 298 ERKRERQRERERER-ERNRKRERERERERERERQRETER-DREKERERKRK 346 Score = 62.8 bits (151), Expect = 4e-10 Identities = 54/224 (24%), Positives = 89/224 (39%), Gaps = 9/224 (4%) Query: 98 DRRTELAKKRLAETQEEISAEVSAKAEKVHELNEEIGKLLAKAEQLGAEGNVDESQKILM 157 DR E + R E + + E + EK +E + + + G + D + Sbjct: 92 DRHRERQRDREKERERQTDRERDRQREKERNRQKERERETEREGERGRDRQTDGQR---- 147 Query: 158 EVEKVRAKKKEAEEEY-RNSMPASSFQQQKLRVCEVCSAYLGLHDNDRRLADHFGGKLHL 216 E E+ R +KE E + R + +QK R E + R + K Sbjct: 148 ERERQRDAEKERERQTDRERQRQTERNRQKEREREKNRQERRERERQREKEN----KTED 203 Query: 217 GFIQIREKLDQLRKTVAEKQEKRNQDRLRRREEREREERLSRRSGSRTRDRRRSRSRDRR 276 + + ++ R+T E + KR DR R R+ + ER + R +R R ++R Sbjct: 204 RHSERGRERERERETETETERKRQTDRERDRQRKTEREREKQAERERASERETERDKERE 263 Query: 277 RRRSRSTSRERRKLSRSRSRDRHRRHRSRSRSHSRGHRRASRDR 320 R R R R+RR+ R R DR R+ R+ + R R+R Sbjct: 264 RERDRDRDRDRRQKERERQTDRKRQRRTERDRETERKRERQRER 307 Score = 59.3 bits (142), Expect = 4e-09 Identities = 38/95 (40%), Positives = 53/95 (55%), Gaps = 6/95 (6%) Query: 229 RKTVAEKQEKRNQDRLRRRE-ERERE-ERLSRRSGSRTRDRRRSRSRDRRRRRSRSTSRE 286 R+ E++ +RN+ R R RE ERERE +R + R + R+R+R R + R R+R T RE Sbjct: 303 RQRERERERERNRKRERERERERERERQRETERDREKERERKRKRQTEMDRERNRQTGRE 362 Query: 287 -RRKLSRSRSRDRHRRHRSRSRSHSRGHRRASRDR 320 RR+ R R R+ R R R + R R RDR Sbjct: 363 GRRQAERERERE---RERDRQSAREREERERDRDR 394 Score = 58.9 bits (141), Expect = 6e-09 Identities = 38/104 (36%), Positives = 52/104 (50%), Gaps = 14/104 (13%) Query: 234 EKQEKRNQDRLRRREERERE-------ERLSRRSGSRTRDRRRSRSRDRRRRRSRSTSRE 286 +++ R ++R RRRE+R+ E ER + R RDR R R RDR + R R T RE Sbjct: 53 DRERNRQKERERRREKRQTERETDRKRERRREKDRHRKRDRHRERQRDREKERERQTDRE 112 Query: 287 R---RKLSRSRSRDRHRR-HRSRSRSHSR---GHRRASRDRSAK 323 R R+ R+R ++R R R R R G R R R A+ Sbjct: 113 RDRQREKERNRQKERERETEREGERGRDRQTDGQRERERQRDAE 156 Score = 57.4 bits (137), Expect = 2e-08 Identities = 34/103 (33%), Positives = 54/103 (52%), Gaps = 5/103 (4%) Query: 222 REKLDQLRKTVAEKQEKRNQDRLRRRE---EREREERLSR-RSGSRTRDRRRSRSRDRRR 277 REK R+T +++ +R +DR R+R+ ER+R+ R R R RDR+R + R+R++ Sbjct: 66 REKRQTERETDRKRERRREKDRHRKRDRHRERQRDREKERERQTDRERDRQREKERNRQK 125 Query: 278 RRSRSTSRERRKLSRSRSRDRHRRHRSRSRSHSRGHRRASRDR 320 R R T RE + R R D R + + R+ R+R Sbjct: 126 ERERETEREGER-GRDRQTDGQRERERQRDAEKERERQTDRER 167 Score = 57.0 bits (136), Expect = 2e-08 Identities = 41/112 (36%), Positives = 60/112 (53%), Gaps = 15/112 (13%) Query: 222 REKLDQLRKTVAEKQEKRNQDRLRRREEREREERLSRRSGSRTRDRR------RSRSRDR 275 REK ++ R+T E+ +R ++R R++ERERE + R G R RDR+ R R RD Sbjct: 101 REK-ERERQTDRERDRQREKER-NRQKERERE---TEREGERGRDRQTDGQRERERQRDA 155 Query: 276 RRRRSRSTSRER-RKLSRSRSRDRHR---RHRSRSRSHSRGHRRASRDRSAK 323 + R R T RER R+ R+R ++R R R R R R + DR ++ Sbjct: 156 EKERERQTDRERQRQTERNRQKEREREKNRQERRERERQREKENKTEDRHSE 207 Score = 56.6 bits (135), Expect = 3e-08 Identities = 55/228 (24%), Positives = 98/228 (42%), Gaps = 30/228 (13%) Query: 99 RRTELAKKRLAETQEEISAEVSAKAEKVHELNEEIGKLLAKAEQLGAEGNVDESQKILME 158 R+TE +++ AE + E E+ E + + + + E+ E D ++ E Sbjct: 236 RKTEREREKQAERERASERETERDKERERERDRDRDRDRRQKER---ERQTDRKRQRRTE 292 Query: 159 VEKVRAKKKEAEEEYRNSMPASSFQQQKLRVCEVCSAYLGLHDNDRRLADHFGGKLHLGF 218 ++ +K+E + E R + ++++ R E + DR Sbjct: 293 RDRETERKRERQRE-RERERERNRKRERERERERERERQRETERDRE------------- 338 Query: 219 IQIREKLDQLRKTVAEKQEKRNQDRLRRRE---EREREERLSRRSGSRTRDRRRSRSRDR 275 + RE+ + R+T +++ R R RR+ ERERE R+S +R R R RDR Sbjct: 339 -KERER-KRKRQTEMDRERNRQTGREGRRQAERERERERERDRQSAREREERERDRDRDR 396 Query: 276 RRRRSRSTSRER---RKLSRSRSRDRHR-----RHRSRSRSHSRGHRR 315 ++ R R T ++R R+ + R R++ R R R R R +G R Sbjct: 397 QKERERQTEKDRDGQRETEKQREREKDRESERGRERGREREKQKGRER 444 Score = 55.5 bits (132), Expect = 6e-08 Identities = 52/225 (23%), Positives = 90/225 (40%), Gaps = 28/225 (12%) Query: 98 DRRTELAKKRLAET---------QEEISAEVSAKAEKVHELNEEIGKLLAKAEQLGAEGN 148 +R TE K+R E Q+E + K ++ E + E + + + E Sbjct: 253 ERETERDKERERERDRDRDRDRRQKERERQTDRKRQRRTERDRETERKRERQRERERERE 312 Query: 149 VDESQKILMEVEKVRAKKKEAEEEYRNSMPASSFQQQKLRVCEVCSAYLGLHDNDRRLAD 208 + ++ E E+ R +++E E + +Q ++ DR Sbjct: 313 RNRKRERERERERERERQRETERDREKERERKRKRQTEM---------------DRERNR 357 Query: 209 HFGGKLHLGFIQIREKLDQLRKTVAEKQEKRNQDRLRRREEREREERLSRRSGSRTRDRR 268 G + + RE+ + + A ++E+R +DR R R++ + R G R +++ Sbjct: 358 QTGREGRRQAERERERERERDRQSAREREERERDRDRDRQKERERQTEKDRDGQRETEKQ 417 Query: 269 RSRSRDRRRRRSRSTSRERRKLSRSRSRDRHR---RHRSRSRSHS 310 R R +DR R R RER K + R RDR R R R R S Sbjct: 418 REREKDRESERGRERGREREK-QKGRERDRERQTDRQAGRQRKRS 461 Score = 55.1 bits (131), Expect = 8e-08 Identities = 35/115 (30%), Positives = 55/115 (47%), Gaps = 14/115 (12%) Query: 220 QIREKLDQLRKTVAEKQEKRNQDRLRRRE-ERERE---ERLSRRSGSRTRDRRRS----- 270 Q + ++ R E++ +R ++R R+RE ER+RE ER +R R+R R Sbjct: 304 QRERERERERNRKRERERERERERERQRETERDREKERERKRKRQTEMDRERNRQTGREG 363 Query: 271 -----RSRDRRRRRSRSTSRERRKLSRSRSRDRHRRHRSRSRSHSRGHRRASRDR 320 R R+R R R R ++RER + R R RDR + ++ G R + R Sbjct: 364 RRQAERERERERERDRQSAREREERERDRDRDRQKERERQTEKDRDGQRETEKQR 418 Score = 54.3 bits (129), Expect = 1e-07 Identities = 34/112 (30%), Positives = 49/112 (43%), Gaps = 9/112 (8%) Query: 222 REKLDQLRKTVAEKQEKRNQDRLRRREEREREERLSRRSGSRTRDRRRSRSRDRRRRRSR 281 R++ + + ++EK Q+R R +RE+E + R R R+R R R + R R Sbjct: 167 RQRQTERNRQKEREREKNRQERRERERQREKENKTEDRHSERGRERERERETETETERKR 226 Query: 282 STSRER---RKLSRSRSRDRHR-----RHRSRSRSHSRGHRRASRDRSAKYK 325 T RER RK R R + R R R + R R RDR + K Sbjct: 227 QTDRERDRQRKTEREREKQAERERASERETERDKERER-ERDRDRDRDRRQK 277 Score = 53.5 bits (127), Expect = 2e-07 Identities = 32/98 (32%), Positives = 50/98 (51%), Gaps = 7/98 (7%) Query: 229 RKTVAEKQEKRNQDRLRRREEREREERLSRRSGSRTRDRRRSRSRDRRRRRSRSTSRERR 288 R+ + + + + D R ++ERE R +R R DR+R R R++ R R R RER+ Sbjct: 39 RRGLGQAHKDADGDDRERNRQKERERRREKRQTERETDRKRERRREKDRHRKRDRHRERQ 98 Query: 289 KLSRSRSRDRHR---RHRSRSRSHSRGHRRASRDRSAK 323 R R ++R R R R R R R +R+ R+R + Sbjct: 99 ---RDREKERERQTDRERDRQREKER-NRQKERERETE 132 Score = 47.8 bits (112), Expect = 1e-05 Identities = 32/105 (30%), Positives = 54/105 (51%), Gaps = 5/105 (4%) Query: 222 REKLDQLRKTVAEKQEKRNQDRLRRREEREREERLSRRSGSRTRDRR--RSRSRDRRRRR 279 REK ++ R+ E++ +R +R R R+ + ER +R + R+R+ R R R R R Sbjct: 117 REK-ERNRQKERERETEREGERGRDRQTDGQRERERQRDAEKERERQTDRERQRQTERNR 175 Query: 280 SRSTSRER-RKLSRSRSRDRHRRHRSRSRSHSRGHRRASRDRSAK 323 + RE+ R+ R R R R + +++ R RG R R+R + Sbjct: 176 QKEREREKNRQERRERERQREKENKTEDRHSERGRER-ERERETE 219 Score = 46.6 bits (109), Expect = 3e-05 Identities = 30/100 (30%), Positives = 49/100 (49%), Gaps = 8/100 (8%) Query: 224 KLDQLRKTVAEKQEKRNQDRLRRREEREREERLSRRSGSRTRDRRRSRSRDRR------R 277 K D+ R+ +++++R + R R+ + +ER ++ R +R R RDR+ R Sbjct: 90 KRDRHRERQRDREKERERQTDRERDRQREKERNRQKERERETEREGERGRDRQTDGQRER 149 Query: 278 RRSRSTSRER-RKLSRSRSRDRHR-RHRSRSRSHSRGHRR 315 R R +ER R+ R R R R R + R R +R RR Sbjct: 150 ERQRDAEKERERQTDRERQRQTERNRQKEREREKNRQERR 189 Score = 42.0 bits (97), Expect = 7e-04 Identities = 42/195 (21%), Positives = 72/195 (36%), Gaps = 49/195 (25%) Query: 96 ECDRRTELAKKRLAETQEEISAEVSAKAEKVHELNEEIGKLLAKAEQLGAEGNVDESQKI 155 E +R E ++R ET+ + E K ++ E++ E + Q G EG ++ Sbjct: 318 ERERERERERERQRETERDREKERERKRKRQTEMDRE------RNRQTGREGRRQAERER 371 Query: 156 LMEVEKVRAKKKEAEEEYRNSMPASSFQQQKLRVCEVCSAYLGLHDNDRRLADHFGGKLH 215 E E+ R +E EE R+ D DR+ Sbjct: 372 ERERERDRQSAREREERERD------------------------RDRDRQK--------- 398 Query: 216 LGFIQIREKLDQLRKTVAEKQEKRNQDRLRRREEREREERLSRRSGSRTRDRRRSRSRDR 275 ++ R+T ++ +R ++ R RE+ ER R R + + R R R+R Sbjct: 399 ----------ERERQTEKDRDGQRETEKQREREKDRESERGRERGREREKQKGRERDRER 448 Query: 276 RRRRSRSTSRERRKL 290 + R R+R L Sbjct: 449 QTDRQAGRQRKRSTL 463 Score = 40.0 bits (92), Expect = 0.003 Identities = 27/74 (36%), Positives = 34/74 (45%), Gaps = 12/74 (16%) Query: 258 RRSGSRTRDRRRSRS----------RDRRRRRSRSTSRERRKLSRSRSRDR-HRRHRSRS 306 RR GS+ RRR R+R R++ R RE+R+ R R R RR + R Sbjct: 29 RRPGSQESPRRRGLGQAHKDADGDDRERNRQKERERRREKRQTERETDRKRERRREKDRH 88 Query: 307 RSHSRGHRRASRDR 320 R R HR RDR Sbjct: 89 RKRDR-HRERQRDR 101 >gi|116008442 zinc finger CCCH-type containing 13 [Homo sapiens] Length = 1564 Score = 63.9 bits (154), Expect = 2e-10 Identities = 75/307 (24%), Positives = 125/307 (40%), Gaps = 25/307 (8%) Query: 19 RDGDETRQRVKFTDDRVCKS--HLLDCCPHDILAGTRMDLGECTKIHDLALRADYEIASK 76 RD +TR R + D R + + D + D HD R + K Sbjct: 459 RDARDTRDRRELRDSRDMRDSREMRDYSRDTKESRDPRDSRSTRDAHDYRDREGRDTHRK 518 Query: 77 ERDLFFELDAMDHLESFIAECDRRTELAKKRLAETQEEISAEVSAKAE-KVHELNEEIGK 135 E D + E ++ + + + E RTE+ + E++ EI + ++ +V EL E+ G Sbjct: 519 E-DTYPE-ESRSYGRNHLREESSRTEIRNESRNESRSEIRNDRMGRSRGRVPELPEK-GS 575 Query: 136 LLAKAEQLGAEGNVDESQKILMEVEKVRAKKKEAEEEYRNSMPASSFQQQKLRVCEVCSA 195 ++ Q+ + + + + E + R+ SSF+++ Sbjct: 576 RGSRGSQIDSHSSNSNYHDSWETRSSYPERDRYPERDNRDQARDSSFERR---------- 625 Query: 196 YLGLHDNDRRLADHFGGKLHLGFIQIREKLDQLRKTVAEKQEKRNQDRLRRREEREREER 255 H R + + I+ + + D+L + E++E+R DR+ R + ER Sbjct: 626 ----HGERDRRDNRERDQRPSSPIRHQGRNDELERD--ERREERRVDRVDDRRDERARER 679 Query: 256 LSRRSGSRTRDRRRSRSRDRRRRRSRSTSRERRKLSRSRSRDRHR-RHRSRSRSHSR-GH 313 R R R+R R R RDR R + R RER + R R R++ R R R R R H R Sbjct: 680 DRERERDRERERERERERDREREKERELERERAR-EREREREKERDRERDRDRDHDRERE 738 Query: 314 RRASRDR 320 R RDR Sbjct: 739 RERERDR 745 Score = 61.2 bits (147), Expect = 1e-09 Identities = 36/94 (38%), Positives = 46/94 (48%), Gaps = 2/94 (2%) Query: 234 EKQEKRNQDRLRRREEREREERLSRRSGSRTRDRRRSRSRDRRRRRSRSTSRERRKLSRS 293 EK+ + ++R R RE +ER R R DR R R R+R R + R RE R+ R Sbjct: 702 EKERELERERAREREREREKERDRERDRDRDHDRERERERERDREKEREREREERERERE 761 Query: 294 RSRDRHR-RHRSRSRSHSRG-HRRASRDRSAKYK 325 R R+R R R R R R+ R R RD K K Sbjct: 762 RERERERERERERERARERDKERERQRDWEDKDK 795 Score = 60.8 bits (146), Expect = 2e-09 Identities = 39/101 (38%), Positives = 50/101 (49%), Gaps = 11/101 (10%) Query: 226 DQLRKTVAEKQEKRNQDRLRRREE---------RERE-ERLSRRSGSRTRDRRRSRSRDR 275 D+ R+ E++ +R ++R R RE+ RERE ER R R RDR R R+R Sbjct: 680 DRERERDRERERERERERDREREKERELERERAREREREREKERDRERDRDRDHDRERER 739 Query: 276 RRRRSRSTSRERRKLSRSRSRDRHR-RHRSRSRSHSRGHRR 315 R R R RER + R R R+R R R R R R R R Sbjct: 740 ERERDREKEREREREERERERERERERERERERERERARER 780 Score = 58.5 bits (140), Expect = 8e-09 Identities = 33/89 (37%), Positives = 44/89 (49%), Gaps = 2/89 (2%) Query: 234 EKQEKRNQDRLRRREEREREERLSRRSGSRTRDRRRSRSRDRRRRRSRSTSRER-RKLSR 292 E++ +R +DR R +E ER R R ++R R R RDR R R RER R+ R Sbjct: 690 ERERERERDREREKERELERERAREREREREKERDRERDRDRDHDRERERERERDREKER 749 Query: 293 SRSRDRHRRHRSRSRSHSRGHRRASRDRS 321 R R+ R R R R R R R+R+ Sbjct: 750 EREREERERERERERERER-ERERERERA 777 Score = 58.2 bits (139), Expect = 1e-08 Identities = 34/98 (34%), Positives = 49/98 (50%), Gaps = 2/98 (2%) Query: 229 RKTVAEKQEKRNQDRLRRREEREREERLSRRSGSRTRDRRRSRSRDRRRRRSRSTSRERR 288 R+ E++++R +R R RE E+ R R RD R R R+R R R + RER Sbjct: 695 RERDREREKERELERERAREREREREKERDRERDRDRDHDRERERERERDREKERERERE 754 Query: 289 KLSRSRSRDRHR-RHRSRSRSHSRGHRRASRDRSAKYK 325 + R R R+R R R R R R +R R R+R ++ Sbjct: 755 ERERERERERERERERERERERAR-ERDKERERQRDWE 791 Score = 57.0 bits (136), Expect = 2e-08 Identities = 37/96 (38%), Positives = 50/96 (52%), Gaps = 4/96 (4%) Query: 229 RKTVAEKQEKRNQDRLRRRE-ERER-EERLSRRSGSRTRDRRRSRSRDRRRRRSRSTSRE 286 R+ E++ +R+++R + RE ERER ER R R R+R R R DR R R R RE Sbjct: 687 RERERERERERDREREKERELERERAREREREREKERDRERDRDRDHDRERERERERDRE 746 Query: 287 RRKLSRSRSRDRHR-RHRSRSRSHSRGHRRA-SRDR 320 + + R+R R R R R R R RA RD+ Sbjct: 747 KEREREREERERERERERERERERERERERARERDK 782 Score = 56.6 bits (135), Expect = 3e-08 Identities = 35/98 (35%), Positives = 49/98 (50%), Gaps = 2/98 (2%) Query: 226 DQLRKTVAEKQEKRNQDRLRRREEREREERLSRRSGSRTRDRRRSRSRDRRRRRSRSTSR 285 D+ R E++ +R +DR + RE REREER R R R+R R R R+R R R + R Sbjct: 728 DRDRDHDRERERERERDREKERE-REREERERERERERERERERERERERARERDKERER 786 Query: 286 ERRKLSRSRSRDRHRRHRSRSRSHSRGHRRASRDRSAK 323 +R + + RD R R R R R +R +K Sbjct: 787 QRDWEDKDKGRDDRREKREEIR-EDRNPRDGHDERKSK 823 Score = 55.1 bits (131), Expect = 8e-08 Identities = 33/87 (37%), Positives = 43/87 (49%), Gaps = 4/87 (4%) Query: 234 EKQEKRNQDRLRRRE-EREREERLSRRSGSRTRDRRRSRSRDRRRRRSRSTSRERRKLSR 292 E+ R+ DR R RE ER+RE+ R R R+R R R R+R R R R +RER K Sbjct: 726 ERDRDRDHDRERERERERDREKEREREREERERERERERERERERERERERARERDK--- 782 Query: 293 SRSRDRHRRHRSRSRSHSRGHRRASRD 319 R R R + + R R R R+ Sbjct: 783 ERERQRDWEDKDKGRDDRREKREEIRE 809 Score = 53.1 bits (126), Expect = 3e-07 Identities = 34/97 (35%), Positives = 55/97 (56%), Gaps = 4/97 (4%) Query: 226 DQLRKTVAEKQEKRNQDRLRRRE-ERERE-ERLSRRSGSRTRDRR-RSRSRDRRRRRSRS 282 ++ R+ E++++R+++R R R+ +RERE ER R R R+R R R R+R R R R Sbjct: 710 ERAREREREREKERDRERDRDRDHDRERERERERDREKEREREREERERERERERERERE 769 Query: 283 TSRERRKLSRSRSRDRHRRHRSRSRSHSRGHRRASRD 319 RER + +R R ++R R+ + R RR R+ Sbjct: 770 RERERER-ARERDKERERQRDWEDKDKGRDDRREKRE 805 Score = 52.4 bits (124), Expect = 6e-07 Identities = 35/99 (35%), Positives = 49/99 (49%), Gaps = 12/99 (12%) Query: 226 DQLRKTVAEKQEKRNQDRLRRREERERE---ERLSRRSGSRTRDRRRSRSRDRRRRR--- 279 D R+ E++ R ++R R REERERE ER R R R+R R R ++R R+R Sbjct: 732 DHDRERERERERDREKEREREREERERERERERERERERERERERARERDKERERQRDWE 791 Query: 280 ----SRSTSRERRKLSRS--RSRDRHRRHRSRSRSHSRG 312 R RE+R+ R RD H +S+ R + G Sbjct: 792 DKDKGRDDRREKREEIREDRNPRDGHDERKSKKRYRNEG 830 Score = 46.2 bits (108), Expect = 4e-05 Identities = 38/91 (41%), Positives = 49/91 (53%), Gaps = 6/91 (6%) Query: 235 KQEKRNQDRLRR-REEREREERLSRRSGSRTRDRRRSRS-RDRRRRRSRSTSRERRKLSR 292 + E+R R +R RE+ REER + S +RD R R RD R RR +R+RR+L Sbjct: 413 RHERREDTRGKRDREKDSREEREYEQDQSSSRDHRDDREPRDGRDRRDARDTRDRRELRD 472 Query: 293 SRS-RD-RHRRHRSRSRSHSRGHR--RASRD 319 SR RD R R SR SR R R++RD Sbjct: 473 SRDMRDSREMRDYSRDTKESRDPRDSRSTRD 503 Score = 45.1 bits (105), Expect = 9e-05 Identities = 47/151 (31%), Positives = 65/151 (43%), Gaps = 35/151 (23%) Query: 198 GLHDNDRRLADHFGGKLHLGFIQIREKLDQLRKTVAEKQEKRNQDRLR-RREEREREERL 256 G HD++R H + H R K D+ + + E++ +++Q R R++RE + Sbjct: 399 GRHDHERTSQSH--DRRHERREDTRGKRDREKDSREEREYEQDQSSSRDHRDDREPRDGR 456 Query: 257 SRRSGSRTRDRRRSR-SRDRRRRRSRSTSRERRKLSR----------SRS---------- 295 RR TRDRR R SRD R SRE R SR SRS Sbjct: 457 DRRDARDTRDRRELRDSRDMR------DSREMRDYSRDTKESRDPRDSRSTRDAHDYRDR 510 Query: 296 --RDRHRR---HRSRSRSHSRGHRRASRDRS 321 RD HR+ + SRS+ R H R R+ Sbjct: 511 EGRDTHRKEDTYPEESRSYGRNHLREESSRT 541 Score = 43.5 bits (101), Expect = 3e-04 Identities = 30/82 (36%), Positives = 39/82 (47%), Gaps = 11/82 (13%) Query: 234 EKQEKRNQDRLRRREEREREERLSRRSGS----RTRDRRRSRSRDRRRRRS--RSTSRER 287 +++++ DR R RE R+ +R R R RDR R R R+R R R R RER Sbjct: 1300 QERDRYEHDRERERERRDTRQREWDRDADKDWPRNRDRDRLRERERERERDKRRDLDRER 1359 Query: 288 RKL-----SRSRSRDRHRRHRS 304 +L R R RDR R S Sbjct: 1360 ERLISDSVERDRDRDRDRTFES 1381 Score = 42.7 bits (99), Expect = 4e-04 Identities = 32/79 (40%), Positives = 39/79 (49%), Gaps = 7/79 (8%) Query: 239 RNQDRLRRREEREREERLSR-RSGSRTRDRR--RSRSRDRRRRRSRSTSRE-RRKLSRSR 294 + +DR ERERE R +R R R D+ R+R RDR R R R R+ RR L R R Sbjct: 1300 QERDRYEHDRERERERRDTRQREWDRDADKDWPRNRDRDRLRERERERERDKRRDLDRER 1359 Query: 295 SR---DRHRRHRSRSRSHS 310 R D R R R R + Sbjct: 1360 ERLISDSVERDRDRDRDRT 1378 Score = 42.0 bits (97), Expect = 7e-04 Identities = 37/112 (33%), Positives = 50/112 (44%), Gaps = 22/112 (19%) Query: 222 REKLDQLRKTVAEKQEKRNQDRLRRREEREREERLSR------RSGSRTRDRRRSRSR-- 273 R+ DQ R + E++ RR+ RER++R S R+ RD RR R Sbjct: 611 RDNRDQARDSSFERRHGERD----RRDNRERDQRPSSPIRHQGRNDELERDERREERRVD 666 Query: 274 ---DRRRRRSRSTSRERRKLSRSRSRDRHR-RHRSRSRSHSRGHRRASRDRS 321 DRR R+R RER R R+R R R R R R + R R+R+ Sbjct: 667 RVDDRRDERARERDRERE-----RDRERERERERERDREREK-ERELERERA 712 Score = 42.0 bits (97), Expect = 7e-04 Identities = 37/108 (34%), Positives = 52/108 (48%), Gaps = 20/108 (18%) Query: 222 REKLDQL------RKTVAEKQEKRNQDRLRRREEREREERLSRRSGS-------RTRDR- 267 + ++DQL R T +++Q+ R+ RR E + ++ RSGS + RDR Sbjct: 1248 KSRIDQLKRGEPSRSTSSDRQDSRSHSS--RRSSPESDRQVHSRSGSFDSRDRLQERDRY 1305 Query: 268 --RRSRSRDRRRRRSRSTSRERRK-LSRSRSRDRHR-RHRSRSRSHSR 311 R R R+RR R R R+ K R+R RDR R R R R R R Sbjct: 1306 EHDRERERERRDTRQREWDRDADKDWPRNRDRDRLRERERERERDKRR 1353 Score = 41.6 bits (96), Expect = 0.001 Identities = 48/227 (21%), Positives = 86/227 (37%), Gaps = 33/227 (14%) Query: 98 DRRTELAKKRLAETQEEISAEVSAKAEKVHELNEEIGKLLAKAEQLGAEGNVDESQKILM 157 +RR E R+ + ++E + E + E+ E E E D ++ Sbjct: 658 ERREERRVDRVDDRRDERARERDRERERDRERERE------------RERERDREREKER 705 Query: 158 EVEKVRAKKKEAEEEYRNSMPASSFQQQKLRVCEVCSAYLGLHDNDRRLADHFGGKLHLG 217 E+E+ RA+++E E E + HD +R + Sbjct: 706 ELERERAREREREREKERDRERDRDRD---------------HDRERERERERDREKERE 750 Query: 218 FIQIREKLDQLRKTVAEKQEKRNQDRLRRREEREREERLSRRSGSRTRDRRRSRSRDRRR 277 + + ++ R+ E++ +R ++R R R ++ERE + + RD RR + + R Sbjct: 751 REREERERERERERERERERERERERARER-DKERERQRDWEDKDKGRDDRREKREEIRE 809 Query: 278 RRSRSTSRERRKLSRSRSRDRHRRHRSRSRSHSRGHRRASRDRSAKY 324 R+ + RK S+ R+R S S S RR S Y Sbjct: 810 DRNPRDGHDERK-----SKKRYRNEGSPSPRQSPKRRREHSPDSDAY 851 Score = 41.2 bits (95), Expect = 0.001 Identities = 41/123 (33%), Positives = 53/123 (43%), Gaps = 10/123 (8%) Query: 200 HDNDRRLADHFGGK---LHLGFIQIREKLDQLRKTVAEKQEKRNQDRLRRREEREREERL 256 +D+ R D G+ LH G + REK L T + K D+L+R E Sbjct: 1211 NDSAHRSGDDQSGRKRVLHSGS-RDREKTKSLEIT---GERKSRIDQLKRGEPSRSTS-- 1264 Query: 257 SRRSGSRTRDRRRSRSRDRRRRRSRSTSRERRKLSRSRSRDRHRRHRSRSRSHSRGHRRA 316 S R SR+ RRS R+ SRS S + R + R R H R R R R +R R Sbjct: 1265 SDRQDSRSHSSRRSSPESDRQVHSRSGSFDSRDRLQERDRYEHDRERERERRDTR-QREW 1323 Query: 317 SRD 319 RD Sbjct: 1324 DRD 1326 Score = 40.4 bits (93), Expect = 0.002 Identities = 28/85 (32%), Positives = 37/85 (43%), Gaps = 2/85 (2%) Query: 238 KRNQDRLRRREEREREERLSRRSGSRTRDRRRSRSRDRRRRRSRST-SRERRKLSRSRSR 296 +R Q R R + R S++ DRR R D R +R R SRE R+ + +S Sbjct: 383 QRKQSPPRHRSPMREKGRHDHERTSQSHDRRHERREDTRGKRDREKDSREEREYEQDQSS 442 Query: 297 DR-HRRHRSRSRSHSRGHRRASRDR 320 R HR R R R +RDR Sbjct: 443 SRDHRDDREPRDGRDRRDARDTRDR 467 Score = 39.3 bits (90), Expect = 0.005 Identities = 31/90 (34%), Positives = 36/90 (40%), Gaps = 5/90 (5%) Query: 233 AEKQEKRNQDRLRRREEREREERLSRRSGSRTRDRRRSRSRDRRRRRSRSTSRERRKLSR 292 A+K RN+DR R RE ER RR R R+R S S +R R R R R Sbjct: 1327 ADKDWPRNRDRDRLRERERERERDKRRDLDRERERLISDSVERDRDRDRD-----RTFES 1381 Query: 293 SRSRDRHRRHRSRSRSHSRGHRRASRDRSA 322 S+ R H R SRD A Sbjct: 1382 SQIESVKRCEAKLEGEHERDLESTSRDSLA 1411 Score = 37.7 bits (86), Expect = 0.014 Identities = 32/99 (32%), Positives = 48/99 (48%), Gaps = 5/99 (5%) Query: 221 IREKLDQLRKTVAEKQEKRNQDRLRRREEREREERLSRRSGSRTRDRRRSRSRDRRRRRS 280 +REK + ++ ++R++ R R +R+RE+ SR R ++ +S SRD R R Sbjct: 395 MREKGRHDHERTSQSHDRRHERREDTRGKRDREKD-SREE--REYEQDQSSSRDHRDDRE 451 Query: 281 RSTSRERRKLSRSRSRDRHRRHRSRSRSHSRGHRRASRD 319 R+RR +RDR SR SR R SRD Sbjct: 452 PRDGRDRR--DARDTRDRRELRDSRDMRDSREMRDYSRD 488 Score = 37.0 bits (84), Expect = 0.024 Identities = 61/264 (23%), Positives = 103/264 (39%), Gaps = 43/264 (16%) Query: 77 ERDLFFELDAMDHLESFIAECDRRTELAKKRLAETQEEISAEVSAKAEKVHELNEEIGKL 136 ERD E +D ++ E R + ++R E + E E + EK EL E + Sbjct: 655 ERDERREERRVDRVDDRRDERARERDRERERDRERERERERERDREREKERELERERARE 714 Query: 137 LAKAEQLGAEGNVDESQKILMEVEKVRAKKKEAEEEYRNSMPASSFQQQKLRVCEVCSAY 196 + + + D + E E+ R + +E E E ++++ R E Sbjct: 715 REREREKERDRERDRDRDHDRERERERERDREKEREREREERERERERERERERE----- 769 Query: 197 LGLHDNDRRLADHFGGKLHLGFIQIREKLDQLRKTVAEKQEKRNQDRLRRREEREREERL 256 + +R A R+K ++ R+ E ++K DR +REE RE+R Sbjct: 770 ---RERERERARE------------RDK-ERERQRDWEDKDKGRDDRREKREEI-REDRN 812 Query: 257 SRRSGSRTRDRRRSRSRDRRR--RRSRSTSRERRKLS-----RSRSRDRHRRHR------ 303 R D R+S+ R R R + + RR+ S + D++ +HR Sbjct: 813 PRDG----HDERKSKKRYRNEGSPSPRQSPKRRREHSPDSDAYNSGDDKNEKHRLLSQVV 868 Query: 304 --SRSRSHSRGHRRASRDRSAKYK 325 SRS S H + DR ++K Sbjct: 869 RPQESRSLSPSH--LTEDRQGRWK 890 Score = 36.2 bits (82), Expect = 0.041 Identities = 30/88 (34%), Positives = 40/88 (45%), Gaps = 5/88 (5%) Query: 242 DRLRRREEREREERLSRRSGSRTRDRRRSRSRDRRRRRSRSTSRER-RKLSRSRSRDRHR 300 D R +ER+R E R R R+R RD + R+ R+R R+ R R RD+ R Sbjct: 1294 DSRDRLQERDRYEHDRERERERRDTRQREWDRDADKDWPRNRDRDRLRERERERERDKRR 1353 Query: 301 ---RHRSRSRSHSRGHRRASRDRSAKYK 325 R R R S S R RDR ++ Sbjct: 1354 DLDRERERLISDS-VERDRDRDRDRTFE 1380 Score = 34.3 bits (77), Expect = 0.16 Identities = 41/133 (30%), Positives = 54/133 (40%), Gaps = 35/133 (26%) Query: 223 EKLDQLRKTVAEKQEKRNQDRLR-------RREEREREERL-------SRRSGSRTRDRR 268 EK++ T+ + Q ++ D+ R R RL + RSG R+ Sbjct: 1166 EKVETPHVTIEDAQHRKPMDQKRSSSLGSNRSNRSHTSGRLRSPSNDSAHRSGDDQSGRK 1225 Query: 269 R---SRSRDRRR---------RRSRSTSRERRKLSRSRSRDRH--RRHRSRSRS------ 308 R S SRDR + R+SR +R + SRS S DR R H SR S Sbjct: 1226 RVLHSGSRDREKTKSLEITGERKSRIDQLKRGEPSRSTSSDRQDSRSHSSRRSSPESDRQ 1285 Query: 309 -HSRGHRRASRDR 320 HSR SRDR Sbjct: 1286 VHSRSGSFDSRDR 1298 Score = 32.7 bits (73), Expect = 0.45 Identities = 61/282 (21%), Positives = 102/282 (36%), Gaps = 70/282 (24%) Query: 110 ETQEEISAEVSAKAEKVHELNEEIGKLLAKAEQLGAEG-NVDESQKILMEVEK----VRA 164 ET + S + VHEL+ E+ + + E + E N+++ ++I+++ E VR+ Sbjct: 145 ETNRDDSDNGDINYDYVHELSLEMKRQKIQRELMKLEQENMEKREEIIIKKEVSPEVVRS 204 Query: 165 K-------KKEAEEEYRNSMPASSFQQQKLRVCEVCSAYLGLHDNDRRL----------- 206 K +K ++ R S P SS +K R S+ L + + Sbjct: 205 KLSPSPSLRKSSKSPKRKSSPKSSSASKKDRKTSAVSSPLLDQQRNSKTNQSKKKGPRTP 264 Query: 207 -------ADHFGGKLHLGFIQIREKLDQLRKTVAEKQEKRNQDRLRRREERERE------ 253 D GK + ++++++++ KT K R+ +R R + ++ R Sbjct: 265 SPPPPIPEDIALGKKYKEKYKVKDRIEE--KTRDGKDRGRDFERQREKRDKPRSTSPAGQ 322 Query: 254 -----------------ERLSRRSGSRTRDRRRSRSRDR------RRRRSRSTSRERRKL 290 + R S S R R S S R RR S S Sbjct: 323 HHSPISSRHHSSSSQSGSSIQRHSPSPRRKRTPSPSYQRTLTPPLRRSASPYPSHSLSSP 382 Query: 291 SRSRSRDRHRR---------HRSRSRSHSRGHRRASRDRSAK 323 R +S RHR H S+SH R H R R + Sbjct: 383 QRKQSPPRHRSPMREKGRHDHERTSQSHDRRHERREDTRGKR 424 Score = 30.4 bits (67), Expect = 2.2 Identities = 30/113 (26%), Positives = 43/113 (38%), Gaps = 10/113 (8%) Query: 222 REKLDQLRKTVAEKQEKRNQDRLRRREEREREERLSRRSGSRTRDRRRSRSRDRRRRRSR 281 RE D R T + + ++ + R+RE R + R + RS R+ R S Sbjct: 480 REMRDYSRDTKESRDPRDSRSTRDAHDYRDREGRDTHRKEDTYPEESRSYGRNHLREESS 539 Query: 282 STS--RERRKLSRS--------RSRDRHRRHRSRSRSHSRGHRRASRDRSAKY 324 T E R SRS RSR R + SRG + S ++ Y Sbjct: 540 RTEIRNESRNESRSEIRNDRMGRSRGRVPELPEKGSRGSRGSQIDSHSSNSNY 592 Score = 30.0 bits (66), Expect = 2.9 Identities = 26/81 (32%), Positives = 35/81 (43%), Gaps = 8/81 (9%) Query: 240 NQDRLRRREEREREERLSRRSGSRTRDRRRSRSRDRRRRRSRSTSRERRKLSRSRSRDRH 299 ++DR + + ER SR + + RS S DR+ RS S SR S + Sbjct: 1232 SRDREKTKSLEITGERKSRIDQLKRGEPSRSTSSDRQDSRSHS--------SRRSSPESD 1283 Query: 300 RRHRSRSRSHSRGHRRASRDR 320 R+ SRS S R RDR Sbjct: 1284 RQVHSRSGSFDSRDRLQERDR 1304 >gi|20127499 arginine/serine-rich splicing factor 6 [Homo sapiens] Length = 344 Score = 62.8 bits (151), Expect = 4e-10 Identities = 44/115 (38%), Positives = 59/115 (51%), Gaps = 4/115 (3%) Query: 207 ADHFGGKLHLGFIQIREKLDQLRKTVAEKQEKRNQDRLRRREEREREERLSRRSGSRTRD 266 AD + + G I+ R D R + N +R E++ R SGSR+R Sbjct: 139 ADAHKERTNEGVIEFRSYSDMKRALDKLDGTEINGRNIRLIEDKPRTSHRRSYSGSRSRS 198 Query: 267 RRRSRSRDRRRRRSRSTSRERRKLSRSRSRDRHRRHRSRSRSHSRGHRRASRDRS 321 R R RSR R RR SRS S R +S+SRSR R R + RSRS S+G + S+ +S Sbjct: 199 RSRRRSRSRSRRSSRSRS---RSISKSRSRSR-SRSKGRSRSRSKGRKSRSKSKS 249 Score = 57.0 bits (136), Expect = 2e-08 Identities = 40/90 (44%), Positives = 50/90 (55%), Gaps = 7/90 (7%) Query: 239 RNQDRLRRREEREREERLSRRSGSRTRDRRRSRSRDRRRRRSRSTSRERRKLSRSRS--- 295 R++ R RRR R R R S RS SR+ + RSRSR R + RSRS S+ R+ S+S+S Sbjct: 195 RSRSRSRRRS-RSRSRR-SSRSRSRSISKSRSRSRSRSKGRSRSRSKGRKSRSKSKSKPK 252 Query: 296 --RDRHRRHRSRSRSHSRGHRRASRDRSAK 323 R H RSRS+ R SR RS K Sbjct: 253 SDRGSHSHSRSRSKDEYEKSRSRSRSRSPK 282 Score = 55.8 bits (133), Expect = 5e-08 Identities = 47/170 (27%), Positives = 76/170 (44%), Gaps = 13/170 (7%) Query: 154 KILMEVEKVRAKKKEAEEEYRNSMPASSFQQQKLRVCEVCSAYLGLHDNDRRLADHFGGK 213 ++++E R ++ ++ R + + K R E + D R L G + Sbjct: 111 RLIVENLSSRCSWQDLKDFMRQAGEVTYADAHKERTNEGVIEFRSYSDMKRALDKLDGTE 170 Query: 214 LH---LGFIQIREKLDQLRKTVAEKQEKRNQDRLRRREEREREERLSRRSGSRTRDRRRS 270 ++ + I+ + + R + R++ R R R R R S SR+R R RS Sbjct: 171 INGRNIRLIEDKPRTSHRRSYSGSRSRSRSRRRSRSRSRRSSRSRSRSISKSRSRSRSRS 230 Query: 271 RSRDRRR---RRSRSTSRERRKL-------SRSRSRDRHRRHRSRSRSHS 310 + R R R R+SRS S+ + K SRSRS+D + + RSRSRS S Sbjct: 231 KGRSRSRSKGRKSRSKSKSKPKSDRGSHSHSRSRSKDEYEKSRSRSRSRS 280 Score = 51.6 bits (122), Expect = 9e-07 Identities = 36/87 (41%), Positives = 46/87 (52%), Gaps = 2/87 (2%) Query: 236 QEKRNQDRLRRREEREREERLSRRSGSRTRDRRRSRSRDRRRRRSRSTSRERRKLSRSRS 295 ++K R R RRS SR+R RSRSR + RSRS SR + + SRSRS Sbjct: 180 EDKPRTSHRRSYSGSRSRSRSRRRSRSRSRRSSRSRSRSISKSRSRSRSRSKGR-SRSRS 238 Query: 296 RDRHRRHRSRSRSHS-RGHRRASRDRS 321 + R R +S+S+ S RG SR RS Sbjct: 239 KGRKSRSKSKSKPKSDRGSHSHSRSRS 265 Score = 40.8 bits (94), Expect = 0.002 Identities = 35/104 (33%), Positives = 48/104 (46%), Gaps = 22/104 (21%) Query: 229 RKTVAEKQEKRNQDRLRRREEREREERLSRRSGSRTRDRR---------RSRSRDRRRRR 279 RK+ ++ + K DR R R + +S SR+R R +S+SR R + R Sbjct: 241 RKSRSKSKSKPKSDRGSHSHSRSRSKDEYEKSRSRSRSRSPKENGKGDIKSKSRSRSQSR 300 Query: 280 SRS------------TSRERRKLSRSRSRDRHRRHRSRSRSHSR 311 S S + +R SRSRSR R + RSRSRS SR Sbjct: 301 SNSPLPVPPSKARSVSPPPKRATSRSRSRSRSKS-RSRSRSSSR 343 Score = 30.0 bits (66), Expect = 2.9 Identities = 14/24 (58%), Positives = 17/24 (70%) Query: 263 RTRDRRRSRSRDRRRRRSRSTSRE 286 R R RSRSR + R RSRS+SR+ Sbjct: 321 RATSRSRSRSRSKSRSRSRSSSRD 344 >gi|41327771 DEAD (Asp-Glu-Ala-Asp) box polypeptide 23 [Homo sapiens] Length = 820 Score = 62.8 bits (151), Expect = 4e-10 Identities = 36/87 (41%), Positives = 46/87 (52%), Gaps = 2/87 (2%) Query: 234 EKQEKRNQDRLRRREEREREERLSRRSGSRTRDRRRSRSRDRRRRRSRSTSRERRKLSRS 293 E++ R DR R R+ + R R+RDRRR SR R R RS+S RERR R Sbjct: 19 ERKRSRTPDRERDRDRDRKSSPSKDRKRHRSRDRRRGGSRSRSRSRSKSAERERRHKERE 78 Query: 294 RSRDRHRRHRSRSRSHSRGHRRASRDR 320 R ++R R + R R GHRR +DR Sbjct: 79 RDKERDRNKKDRDRDKD-GHRR-DKDR 103 Score = 60.8 bits (146), Expect = 2e-09 Identities = 37/109 (33%), Positives = 57/109 (52%), Gaps = 9/109 (8%) Query: 224 KLDQLRKTVAEKQEKRNQDRLRR--REEREREERLSRRSGSRTRDRRRSRSRDRRRR--- 278 K ++ R +++ R++DR ++ + R RR GSR+R R RS+S +R RR Sbjct: 17 KEERKRSRTPDRERDRDRDRKSSPSKDRKRHRSRDRRRGGSRSRSRSRSKSAERERRHKE 76 Query: 279 RSRSTSRERRKLSRSRSRDRHRRHRSRSRSHSRGHR----RASRDRSAK 323 R R R+R K R R +D HRR + R RS R ++ +DR +K Sbjct: 77 RERDKERDRNKKDRDRDKDGHRRDKDRKRSSLSPGRGKDFKSRKDRDSK 125 Score = 59.7 bits (143), Expect = 3e-09 Identities = 37/94 (39%), Positives = 52/94 (55%), Gaps = 12/94 (12%) Query: 234 EKQEKRNQDRLRRREEREREERLSRRSGSRTRDRRRSRSRDRRRRRSRSTSRERRK---- 289 E +K+++D +EER+R R R R RDR+ S S+DR+R RS R+RR+ Sbjct: 4 ELADKKDRDASPSKEERKRS-RTPDRERDRDRDRKSSPSKDRKRHRS----RDRRRGGSR 58 Query: 290 ---LSRSRSRDRHRRHRSRSRSHSRGHRRASRDR 320 SRS+S +R RRH+ R R R + RDR Sbjct: 59 SRSRSRSKSAERERRHKERERDKERDRNKKDRDR 92 Score = 34.3 bits (77), Expect = 0.16 Identities = 21/93 (22%), Positives = 45/93 (48%), Gaps = 11/93 (11%) Query: 222 REKLDQLRKTVAEKQEKRNQ---------DRLRRREEREREERLSRRSGSRTRDRRRSRS 272 ++++++ ++ + E+++KR Q + + RE RER ER+ R + + R + Sbjct: 178 QQEVEERQRMLEEERKKRKQFQDLGRKMLEDPQERERRERRERMERETNGNEDEEGRQKI 237 Query: 273 RDRRRRRSRSTSRERRKLS--RSRSRDRHRRHR 303 R+ + + + + R L + R R RH R Sbjct: 238 REEKDKSKELHAIKERYLGGIKKRRRTRHLNDR 270 Score = 33.9 bits (76), Expect = 0.20 Identities = 31/105 (29%), Positives = 43/105 (40%), Gaps = 22/105 (20%) Query: 226 DQLRKTVAEKQEKRNQDRLRRR-------------EEREREERLSRRSGSRTR---DRRR 269 D+ RK+ K KR++ R RRR ERER + R R R DR R Sbjct: 33 DRDRKSSPSKDRKRHRSRDRRRGGSRSRSRSRSKSAERERRHKERERDKERDRNKKDRDR 92 Query: 270 SRSRDRRRRRSRSTSRERRKLSRSRSRD-RHRRHRSRSRSHSRGH 313 + RR + R+R LS R +D + R+ R + H Sbjct: 93 DKDGHRRDK-----DRKRSSLSPGRGKDFKSRKDRDSKKDEEDEH 132 Score = 30.4 bits (67), Expect = 2.2 Identities = 19/98 (19%), Positives = 43/98 (43%), Gaps = 4/98 (4%) Query: 223 EKLDQLRKTVAEKQEKRNQDRLRRREEREREERLSRRSGSRTRDRRRSRSRDRRRRRSRS 282 E L + ++ V E+Q ++R +R++ ++ L R+ ++R R R+R R + Sbjct: 172 EALKRRQQEVEERQRMLEEERKKRKQFQD----LGRKMLEDPQERERRERRERMERETNG 227 Query: 283 TSRERRKLSRSRSRDRHRRHRSRSRSHSRGHRRASRDR 320 E + +D+ + + + G ++ R R Sbjct: 228 NEDEEGRQKIREEKDKSKELHAIKERYLGGIKKRRRTR 265 Score = 29.6 bits (65), Expect = 3.8 Identities = 23/90 (25%), Positives = 38/90 (42%), Gaps = 5/90 (5%) Query: 233 AEKQEKRNQDRLRRREERER--EERLSRRSGSRTRDRRRSRSRDRRRRRSRSTSRERRKL 290 AE++ + + R + EER+R EE +R + R+ R RR R RER + Sbjct: 167 AEREAEALKRRQQEVEERQRMLEEERKKRKQFQDLGRKMLEDPQERERRER---RERMER 223 Query: 291 SRSRSRDRHRRHRSRSRSHSRGHRRASRDR 320 + + D R + R A ++R Sbjct: 224 ETNGNEDEEGRQKIREEKDKSKELHAIKER 253 Score = 28.5 bits (62), Expect = 8.5 Identities = 18/92 (19%), Positives = 35/92 (38%), Gaps = 6/92 (6%) Query: 234 EKQEKRNQDRLRRREEREREERLSRRSGSRTRDRRRSRSRDRRRRRSRSTSRERRKLSRS 293 +K E+ + + + + ERE +R +R+R +R++R ++ + L R Sbjct: 151 KKAEEEAEAKPKFLSKAEREAEALKRRQQEVEERQRMLEEERKKR------KQFQDLGRK 204 Query: 294 RSRDRHRRHRSRSRSHSRGHRRASRDRSAKYK 325 D R R R + D + K Sbjct: 205 MLEDPQERERRERRERMERETNGNEDEEGRQK 236 >gi|4759100 splicing factor, arginine/serine-rich 11 [Homo sapiens] Length = 484 Score = 62.4 bits (150), Expect = 5e-10 Identities = 36/99 (36%), Positives = 51/99 (51%), Gaps = 10/99 (10%) Query: 234 EKQEKRNQDRLRRREERER----------EERLSRRSGSRTRDRRRSRSRDRRRRRSRST 283 +K+EKR R R R R R R RRS S++R RRRS+S RRR SR Sbjct: 241 KKEEKRRHSRSRSRSRRRRTPSSSRHRRSRSRSRRRSHSKSRSRRRSKSPRRRRSHSRER 300 Query: 284 SRERRKLSRSRSRDRHRRHRSRSRSHSRGHRRASRDRSA 322 R R S++R + + + + RS++ + + A R RSA Sbjct: 301 GRRSRSTSKTRDKKKEDKEKKRSKTPPKSYSTARRSRSA 339 Score = 58.9 bits (141), Expect = 6e-09 Identities = 44/107 (41%), Positives = 55/107 (51%), Gaps = 4/107 (3%) Query: 217 GFIQIREKLDQLRKTVAE--KQEKRNQDRLRRREEREREERLSRRSGSRTRDRRRSRSRD 274 G + K D K + E K+ + Q + E +++E R S SR+R RRR Sbjct: 204 GLVSPSLKSDTSSKEIEEAMKRVREAQSLISAAIEPDKKEEKRRHSRSRSRSRRRRTPSS 263 Query: 275 RRRRRSRSTSRERRKLSRSRSRDRHRRHRSRSRSHSRGHRRASRDRS 321 R RRSRS SR RR S+SRSR R + R R RSHSR R SR S Sbjct: 264 SRHRRSRSRSR-RRSHSKSRSRRRSKSPR-RRRSHSRERGRRSRSTS 308 Score = 58.2 bits (139), Expect = 1e-08 Identities = 41/133 (30%), Positives = 59/133 (44%), Gaps = 29/133 (21%) Query: 222 REKLDQLRKTVAEKQEKRNQDRLRRREEREREERLSRRSGSRTRDRR------------- 268 R + R++ ++ + +R RRR RE RS S+TRD++ Sbjct: 268 RSRSRSRRRSHSKSRSRRRSKSPRRRRSHSRERGRRSRSTSKTRDKKKEDKEKKRSKTPP 327 Query: 269 ---------RSRSRDRRRRRSRSTSRE-------RRKLSRSRSRDRHRRHRSRSRSHSRG 312 RS SR+RRRRRSRS +R +RKLSRS S RH++ + + + R Sbjct: 328 KSYSTARRSRSASRERRRRRSRSGTRSPKKPRSPKRKLSRSPSPRRHKKEKKKDKDKERS 387 Query: 313 HRRASRDRSAKYK 325 R S K K Sbjct: 388 RDERERSTSKKKK 400 Score = 37.7 bits (86), Expect = 0.014 Identities = 30/116 (25%), Positives = 49/116 (42%), Gaps = 9/116 (7%) Query: 161 KVRAKKKEAEEEYRNSMPASSFQQQKLRVCEVCSAYLGLHDNDRRLADHFGGKLHLGFIQ 220 K R KKKE +E+ R+ P S+ + RR G + Sbjct: 309 KTRDKKKEDKEKKRSKTPPKSYSTARRS--------RSASRERRRRRSRSGTRSPKKPRS 360 Query: 221 IREKLDQLRKTVAEKQEKR-NQDRLRRREEREREERLSRRSGSRTRDRRRSRSRDR 275 + KL + K+EK+ ++D+ R R+ERER ++S + +DR R D+ Sbjct: 361 PKRKLSRSPSPRRHKKEKKKDKDKERSRDERERSTSKKKKSKDKEKDRERKSESDK 416 Score = 37.7 bits (86), Expect = 0.014 Identities = 21/80 (26%), Positives = 39/80 (48%), Gaps = 4/80 (5%) Query: 229 RKTVAEKQEKRNQDRLRRR---EEREREERLSRRSGSRTRDRRRSRSRDRRRRR-SRSTS 284 R A ++ +R + R R + R + +LSR R + + + +D+ R R R S Sbjct: 335 RSRSASRERRRRRSRSGTRSPKKPRSPKRKLSRSPSPRRHKKEKKKDKDKERSRDERERS 394 Query: 285 RERRKLSRSRSRDRHRRHRS 304 ++K S+ + +DR R+ S Sbjct: 395 TSKKKKSKDKEKDRERKSES 414 >gi|4827046 U2 small nuclear RNA auxiliary factor 1-like 2 [Homo sapiens] Length = 482 Score = 62.0 bits (149), Expect = 7e-10 Identities = 40/88 (45%), Positives = 50/88 (56%), Gaps = 2/88 (2%) Query: 238 KRNQDRLRRREEREREERLSRRSGSRTRDRRRSRSRDRRRRRSRSTSRERRKLSRSRS-R 296 KRN + R+ ++ R S SR R RSR R+R R R RS R R SRSRS R Sbjct: 390 KRNGESERKSSRHRGKKSHKRTSKSRERHNSRSRGRNRDRSRDRSRGRGSRSRSRSRSRR 449 Query: 297 DRHRRHRSRSRSHSRGHRRA-SRDRSAK 323 R R +S SRS SRG RR+ +RDR+ + Sbjct: 450 SRRSRSQSSSRSRSRGRRRSGNRDRTVQ 477 Score = 45.8 bits (107), Expect = 5e-05 Identities = 42/108 (38%), Positives = 55/108 (50%), Gaps = 26/108 (24%) Query: 201 DNDRRLADHFGGKLHLGFIQIREKLDQLRKTVAEKQEKRNQDRLRRREEREREERLSRRS 260 +++R+ + H G K H + RE+ + + RN+DR R R SR Sbjct: 394 ESERKSSRHRGKKSHKRTSKSRERHNS-------RSRGRNRDRSRDR---------SRGR 437 Query: 261 GSRTRDRRRSRSRDRRRRRSRSTSRERRKLSRSRSRDRHRRHRSRSRS 308 GSR+ RSRSR RR RRSRS S SRSRSR R RR +R R+ Sbjct: 438 GSRS----RSRSRSRRSRRSRSQSS-----SRSRSRGR-RRSGNRDRT 475 Score = 28.9 bits (63), Expect = 6.5 Identities = 11/56 (19%), Positives = 32/56 (57%) Query: 220 QIREKLDQLRKTVAEKQEKRNQDRLRRREEREREERLSRRSGSRTRDRRRSRSRDR 275 +I+++ ++ K E+QE++ +++ ++ +EREE +R + ++ + D+ Sbjct: 87 RIKKEKEEAAKKRQEEQERKLKEQWEEQQRKEREEEEQKRQEKKEKEEALQKMLDQ 142 >gi|24762236 PRP38 pre-mRNA processing factor 38 (yeast) domain containing A [Homo sapiens] Length = 312 Score = 62.0 bits (149), Expect = 7e-10 Identities = 55/179 (30%), Positives = 79/179 (44%), Gaps = 23/179 (12%) Query: 158 EVEKVRAKKKEAEEEYRNSMPASSFQQQKL---RVCEVCSAYLGLHDNDRRLADHFGGKL 214 + K++++ + E E M F + L RVC++ L +R +L Sbjct: 126 DYRKIKSQNRNGEFEL---MHVDEFIDELLHSERVCDIILPRL-----QKRYVLEEAEQL 177 Query: 215 HLGFIQIREKLDQLRKTVAEKQEKRNQDRLRRREEREREER-LSRRSGSRTRDRRRSRSR 273 + E +D + + E++E +R+ + R R R L + S T RRSRSR Sbjct: 178 EPRVSALEEDMDDVESSEEEEEEDEKLERVPSPDHRRRSYRDLDKPRRSPTLRYRRSRSR 237 Query: 274 DRRRR------RSRSTSRERRKLS-----RSRSRDRHRRHRSRSRSHSRGHRRASRDRS 321 RRR RS S RER + RSRSRDR R RS+S H R HR S +S Sbjct: 238 SPRRRSRSPKRRSPSPRRERHRSKSPRRHRSRSRDRRHRSRSKSPGHHRSHRHRSHSKS 296 Score = 61.2 bits (147), Expect = 1e-09 Identities = 38/99 (38%), Positives = 49/99 (49%), Gaps = 1/99 (1%) Query: 226 DQLRKTVAEKQEKRNQDRLRRREEREREERLSRRSGSR-TRDRRRSRSRDRRRRRSRSTS 284 D R++ + + R LR R R R R RS R + RR R R + RR RS S Sbjct: 211 DHRRRSYRDLDKPRRSPTLRYRRSRSRSPRRRSRSPKRRSPSPRRERHRSKSPRRHRSRS 270 Query: 285 RERRKLSRSRSRDRHRRHRSRSRSHSRGHRRASRDRSAK 323 R+RR SRS+S HR HR RS S S + S +S + Sbjct: 271 RDRRHRSRSKSPGHHRSHRHRSHSKSPERSKKSHKKSRR 309 >gi|148746195 trichohyalin [Homo sapiens] Length = 1943 Score = 61.6 bits (148), Expect = 9e-10 Identities = 50/222 (22%), Positives = 96/222 (43%), Gaps = 12/222 (5%) Query: 98 DRRTELAKKRLAETQEEISAEVSAKAEKVHELNEEIGKLLAKAEQLGAEGNVDESQKILM 157 +RR L ++ E E+ + K ++ E E KL E+ E Q++ Sbjct: 453 ERRDWLKREEETERHEQERRKQQLKRDQEEERRERWLKL---EEEERREQQERREQQLRR 509 Query: 158 EVEKVRAKKKEAEEEYRNSMPASSFQQQKLRVCEVCSAYLGLHDNDRRLADHFGGKLHLG 217 E E+ R ++ + +EE +QQ R E L + ++RL + Sbjct: 510 EQEERREQRLKRQEEEERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQERREQ---- 565 Query: 218 FIQIREKLDQLRKTVAEKQEKRNQDRLRRREEREREERLSRRSGSRTRDRRRSRSRDRRR 277 +++ + ++ R + +++E+R Q RL+R +E E+RL R R R R++R Sbjct: 566 --RLKREQEERRDQLLKREEERRQQRLKREQEERLEQRLKREEVERLEQEER---REQRL 620 Query: 278 RRSRSTSRERRKLSRSRSRDRHRRHRSRSRSHSRGHRRASRD 319 +R R++L +S ++ R+ + R R +R R+ Sbjct: 621 KREEPEEERRQQLLKSEEQEERRQQQLRREQQERREQRLKRE 662 Score = 54.7 bits (130), Expect = 1e-07 Identities = 54/250 (21%), Positives = 110/250 (44%), Gaps = 25/250 (10%) Query: 91 ESFIAECDRRTELAKKRLAETQEEISAEVSAKAEKVHELNEEIGKLLAKAEQLGA----- 145 E +AE + ++E ++ ++ E+ + ++ E E A+ EQL + Sbjct: 145 ERELAEGEEQSEKQERLEQRDRQRRDEELWRQRQEWQEREER----RAEEEQLQSCKGHE 200 Query: 146 -EGNVDESQKILMEVEKVRAKKKEAEEEYRNSMPASSFQQQKLRVCEVCSAYLGLHDNDR 204 E DE Q E+ ++R K +E +++ R FQ+++ + E L + Sbjct: 201 TEEFPDEEQLRRRELLELRRKGREEKQQQRRERQDRVFQEEEEK--EWRKRETVLRKEEE 258 Query: 205 RLADHFGGKLHLGFIQIREKLDQLRKTVAEK------QEKRNQDRLRRREE---REREER 255 +L + + +++E+ +QLRK ++ +E++ Q RLRR ++ ++ EER Sbjct: 259 KLQEEEPQRQR----ELQEEEEQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEEER 314 Query: 256 LSRRSGSRTRDRRRSRSRDRRRRRSRSTSRERRKLSRSRSRDRHRRHRSRSRSHSRGHRR 315 ++ R + RR + +RR ++ R ERR+ R ++ RR + R R Sbjct: 315 REQQEERREQQERREQQEERREQQLRREQEERREQQLRREQEEERREQQLRREQEEERRE 374 Query: 316 ASRDRSAKYK 325 R + + Sbjct: 375 QQLRREQQLR 384 Score = 54.7 bits (130), Expect = 1e-07 Identities = 51/221 (23%), Positives = 97/221 (43%), Gaps = 30/221 (13%) Query: 108 LAETQEEISAEVSAKAEKVHELNEEIGKLLAKAEQLGAEGNVDESQKILMEVEKVRAKKK 167 L + +E++ E + ++ E E++ KL + ++L E +E Q+ + E+ +K+ Sbjct: 253 LRKEEEKLQEEEPQRQRELQEEEEQLRKL--ERQELRRERQEEEQQQQRLRREQQLRRKQ 310 Query: 168 EAEEEYRNSMPASSFQQQKLRVCEVCSAYLGLHDNDRRLADHFGGKLHLGFIQIREKLDQ 227 E E QQ++ R +RR + L Q + Q Sbjct: 311 EEERRE---------QQEERR-----------EQQERREQQEERREQQLRREQEERREQQ 350 Query: 228 LRKTVAEKQEKRNQDRLRRREEREREERLSRRSGSRTRDRRRSRSRDRRR----RRSRST 283 LR+ E++E+R + +LRR +E ER E+ RR R+++ R + RR RR + Sbjct: 351 LRR---EQEEERREQQLRREQEEERREQQLRREQQLRREQQLRREQQLRREQQLRREQQL 407 Query: 284 SRERR-KLSRSRSRDRHRRHRSRSRSHSRGHRRASRDRSAK 323 RE++ + + R++ R H + H + R++ K Sbjct: 408 RREQQLRREQQLRREQQLRREQEEERHEQKHEQERREQRLK 448 Score = 53.9 bits (128), Expect = 2e-07 Identities = 49/225 (21%), Positives = 96/225 (42%), Gaps = 30/225 (13%) Query: 99 RRTELAKKRLAETQEEISAEVSAKAEKVHELNEEIGKLLAKAEQLGAEGNVDESQKILME 158 R +L +++ ++++ E + E+ E +E+ K EQ E Q++ E Sbjct: 403 REQQLRREQQLRREQQLRREQQLRREQEEERHEQ------KHEQERRE------QRLKRE 450 Query: 159 VEKVRAKKKEAEEEYRNSMPASSFQQQKLRVCEVCSAYLGLHDNDRRLADHFGGKLHLGF 218 E+ R K EE R+ Q ++ + E +L L + +RR Sbjct: 451 QEERRDWLKREEETERHEQERRKQQLKRDQEEERRERWLKLEEEERR------------- 497 Query: 219 IQIREKLDQLRKTVAEKQEKRNQDRLRRREEREREERLSRRSGSRTRDRRRSRSRDRRRR 278 E+ ++ + + +QE+R + RL+R+EE ER ++ R R++ R + +R Sbjct: 498 ----EQQERREQQLRREQEERREQRLKRQEEEERLQQRLRSEQQLRREQEERREQLLKRE 553 Query: 279 RSRSTSRERRKLSRSRSRDRHRRHRSRSRSHSRGHRRASRDRSAK 323 + +ERR+ R + RR + R R +R R++ + Sbjct: 554 EEKRLEQERRE-QRLKREQEERRDQLLKREEERRQQRLKREQEER 597 Score = 52.4 bits (124), Expect = 6e-07 Identities = 53/226 (23%), Positives = 99/226 (43%), Gaps = 33/226 (14%) Query: 102 ELAKKRLAETQEEISAEVSAKAEKVHE--LNEEIGKLLAKAEQLGAEGNVDESQKILMEV 159 E +++ E Q+ + E K + E L +E KL + Q E +E Q +E Sbjct: 224 EEKQQQRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQRELQEEEEQLRKLER 283 Query: 160 EKVRAKKKEAEEEYRNSMPASSFQQQKLRVCEVCSAYLGLHDNDRRLADHFGGKLHLGFI 219 +++R +++E E+ QQQ+LR + + +RR Sbjct: 284 QELRRERQEEEQ-----------QQQRLRREQQLRRK---QEEERRE------------- 316 Query: 220 QIREKLDQLRKTVAEKQEKRNQDRLRRREEREREERLSRRSGSRTRDR--RRSRSRDRRR 277 Q E+ +Q + E+QE+R + +LRR +E RE++L R R++ RR + +RR Sbjct: 317 QQEERREQQERR--EQQEERREQQLRREQEERREQQLRREQEEERREQQLRREQEEERRE 374 Query: 278 RRSRSTSRERRKLSRSRSRDRHRRHRSRSRSHSRGHRRASRDRSAK 323 ++ R + RR+ R + R + R R ++ R++ + Sbjct: 375 QQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLR 420 Score = 50.1 bits (118), Expect = 3e-06 Identities = 51/212 (24%), Positives = 95/212 (44%), Gaps = 37/212 (17%) Query: 99 RRTELAKKRLAETQEEISAEVSAKAEKVHELNEEIGKLLAKAEQLGAEGNVDESQKILME 158 RR E +K L E Q+ + E+ + EE L + EQ + +K L E Sbjct: 1440 RRQERERKFLEEEQQ-------LRQERHRKFREEEQLLQEREEQ--QLHRQERDRKFLEE 1490 Query: 159 VEKVRAKKKEA---EEEYRNSMPASSFQQQKLRVCEVCSAYLGLHDNDRRLADHFGGKLH 215 +++R ++++ E+E R+ P F +++ + LH R+ Sbjct: 1491 EQQLRRQERDRKFREQELRSQEPERKFLEEEQQ----------LHRQQRQRK-------- 1532 Query: 216 LGFIQIREKLDQLRKTVAEKQEKRNQDRLRRREEREREERLSRRSGSRTRDR--RRSRSR 273 F+Q + QLR+ +Q ++++DR R EE+ R+ER ++ + RDR R + Sbjct: 1533 --FLQEEQ---QLRRQERGQQRRQDRDRKFREEEQLRQEREEQQLSRQERDRKFRLEEQK 1587 Query: 274 DRRRRRSRSTSRERRKLSRSRSRDRHRRHRSR 305 RR+ + R + ++L R + + R+ R R Sbjct: 1588 VRRQEQERKFMEDEQQLRRQEGQQQLRQERDR 1619 Score = 49.3 bits (116), Expect = 5e-06 Identities = 55/224 (24%), Positives = 97/224 (43%), Gaps = 13/224 (5%) Query: 98 DRRTELAKKRLAETQEEISAEVSAKAEKVHELNEEIGKLLAKAEQLGAEGNVDESQKILM 157 +RR + K++ E +E + + ++ + E E +LL + E+ E E Q++ Sbjct: 513 ERREQRLKRQ--EEEERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQERRE-QRLKR 569 Query: 158 EVEKVRAKKKEAEEEYRNSMPASSFQQQKLRVCEVCSAYLGLHDNDRRLADHFGGKLHLG 217 E E+ R + + EEE R Q+++L L +RR + Sbjct: 570 EQEERRDQLLKREEE-RRQQRLKREQEERLEQRLKREEVERLEQEERREQRLKREEPE-- 626 Query: 218 FIQIREKLDQLRKTVAEKQEKRNQDRLRRREEREREERLSRRSGSRTRDRRRSRSRDRRR 277 E+ QL K+ E+QE+R Q +LRR ++ RE+RL R ++R R + R Sbjct: 627 ----EERRQQLLKS--EEQEERRQQQLRREQQERREQRLKREEEEERLEQRLKREHEEER 680 Query: 278 RRSRSTSRERRKL-SRSRSRDRHRRHRSRSRSHSRGHRRASRDR 320 R E+ + R +SR + + S + +R + SR R Sbjct: 681 REQELAEEEQEQARERIKSRIPKWQWQLESEADARQSKVYSRPR 724 Score = 48.9 bits (115), Expect = 6e-06 Identities = 52/240 (21%), Positives = 98/240 (40%), Gaps = 42/240 (17%) Query: 99 RRTELAKKRLAETQEEISAEVSAKAEKVHELNEEIGKLLAKAEQLGAEGNVDESQKILME 158 R E +++L + +EE E + +++ EE L K E+ + + Q+ +E Sbjct: 540 REQEERREQLLKREEEKRLEQERREQRLKREQEERRDQLLKREEERRQQRLKREQEERLE 599 Query: 159 -------VEKV--------RAKKKEAEEEYRNSMPASSFQQQKLRVCEVCSAYLGLHDND 203 VE++ R K++E EEE R + S Q+++ + L + Sbjct: 600 QRLKREEVERLEQEERREQRLKREEPEEERRQQLLKSEEQEERRQ------QQLRREQQE 653 Query: 204 RRLADHFGGKLHLGFIQIREKLDQLRKTVAEKQEKRNQDRLRRREEREREERLSRR---- 259 RR + L + E+L+Q K E +E+R + L E+ + ER+ R Sbjct: 654 RR-------EQRLKREEEEERLEQRLKR--EHEEERREQELAEEEQEQARERIKSRIPKW 704 Query: 260 --------SGSRTRDRRRSRSRDRRRRRSRSTSRERRKLSRSRSRDRHRRHRSRSRSHSR 311 +++ R R ++ +RRR + RR+ S + ++ R HR + R Sbjct: 705 QWQLESEADARQSKVYSRPRKQEGQRRRQEQEEKRRRRESELQWQEEERAHRQQQEEEQR 764 Score = 48.1 bits (113), Expect = 1e-05 Identities = 58/262 (22%), Positives = 108/262 (41%), Gaps = 26/262 (9%) Query: 76 KERDLFFELDAMDHLESFIAECDRRTELAKKRLAETQEEISAEVSAKAEKVHELNEEIGK 135 ++RD F + E + R+ K RL E + + E +L + G+ Sbjct: 1551 QDRDRKFREEEQLRQEREEQQLSRQERDRKFRLEEQKVRRQEQERKFMEDEQQLRRQEGQ 1610 Query: 136 LLAKAEQLGAEGNVDESQKILMEVEKVRAKKKEAEEEYRNSMPASSFQQQKLRVCEVCSA 195 + E+ + E +++L E E+ + ++E + ++ P Q+++ ++ Sbjct: 1611 QQLRQER---DRKFREDEQLLQEREEQQLHRQERDRKFLEEEPQLRRQEREQQL------ 1661 Query: 196 YLGLHDNDRRLADHFGGKLHLGFIQIREKLDQLRKTVAEKQEKRNQDRLR---------R 246 HD DR+ + L G Q + ++ RK E+Q+ R Q+R R R Sbjct: 1662 ---RHDRDRKFREE-EQLLQEGEEQQLRRQERDRKFREEEQQLRRQERERKFLQEEQQLR 1717 Query: 247 REERE---REERLSRRSGSRTRDRRRSRSRDRRRRRSRSTSRERRKLSRSRSRDRHRRHR 303 R+E E REE R+ + + RR+ R R RE ++L R + RDR R Sbjct: 1718 RQELERKFREEEQLRQETEQEQLRRQERYRKILEEEQLRPEREEQQL-RRQERDRKFREE 1776 Query: 304 SRSRSHSRGHRRASRDRSAKYK 325 + R + S++ K++ Sbjct: 1777 EQLRQEREEQQLRSQESDRKFR 1798 Score = 46.2 bits (108), Expect = 4e-05 Identities = 45/206 (21%), Positives = 89/206 (43%), Gaps = 24/206 (11%) Query: 100 RTELAKKRLAETQEEISAEVSAKAEKVHELNEE--IGKLLAKAEQLGAEGNVDESQKILM 157 R E K+RL E + + E + E+ L EE + Q E + + ++ L+ Sbjct: 1035 REEREKRRLQERERQYREEEELQQEEEQLLGEERETRRRQELERQYRKEEELQQEEEQLL 1094 Query: 158 EVEKVRAKKKEAEEEYRNSMPASSFQQQKLRVCEVCSAYLGLHDNDRRLADHFGGKLHLG 217 E + +++E E + R ++Q LR + ++R + + Sbjct: 1095 REEPEKRRRQERERQCREEEELQQEEEQLLR-----------EEREKRRRQELE-RQYRE 1142 Query: 218 FIQIREKLDQLRKTVAEKQEKRNQDRLRRREE--REREERLSRRSGSRTRDRRRSRSRDR 275 +++++ +QL + EK+ ++ +R R EE ++ EE+L R +R + R+R Sbjct: 1143 EEEVQQEEEQLLREEPEKRRRQELERQYREEEELQQEEEQLLRE-----EQEKRRQERER 1197 Query: 276 RRRRSRSTSRERRKLSRSRSRDRHRR 301 + R R++RK R RD +R Sbjct: 1198 QYREEEELQRQKRK---QRYRDEDQR 1220 Score = 46.2 bits (108), Expect = 4e-05 Identities = 54/232 (23%), Positives = 100/232 (43%), Gaps = 37/232 (15%) Query: 100 RTELAKKRLAETQEEISAEVSAKAEKVHELNEEIGKLLAKAEQLGAEGNVDESQKILMEV 159 R E K+R E + + E + E+ L EE K + E+ E E+ Sbjct: 1155 REEPEKRRRQELERQYREEEELQQEEEQLLREEQEKRRQERERQYREEE---------EL 1205 Query: 160 EKVRAKKKEAEEEYRNSMPASSFQQQKLRVCEVCSAYLGLHDND--RRLADHFGGKLHLG 217 ++ + K++ +E+ R+ + ++ +K Y +N+ R+L D Sbjct: 1206 QRQKRKQRYRDEDQRSDLKWQ-WEPEKENAVRDNKVYCKGRENEQFRQLEDS-------- 1256 Query: 218 FIQIREKLDQ--LRKTVAEKQEKRNQDRLRRREERER----EERLSRRSGSRTRDRRRSR 271 Q+R++ Q L+ + E+QE+ + RR ++R+R EE+L R +++ ++ Sbjct: 1257 --QLRDRQSQQDLQHLLGEQQERDREQERRRWQQRDRHFPEEEQLER------EEQKEAK 1308 Query: 272 SRDRRRRRSRSTSRERRKLSRSRSR-DRHRRHRSR--SRSHSRGHRRASRDR 320 RDR+ + + RE R+ R R DR R + + RR RDR Sbjct: 1309 RRDRKSQEEKQLLREEREEKRRRQETDRKFREEEQLLQEREEQPLRRQERDR 1360 Score = 45.8 bits (107), Expect = 5e-05 Identities = 47/234 (20%), Positives = 92/234 (39%), Gaps = 31/234 (13%) Query: 100 RTELAKKRLAETQEEISAEVSAKAEKVHELNEEIGK--LLAKAEQLGAEGNVDESQKILM 157 R E K+R E + + + + E+ L EE K L + Q E + + ++ L+ Sbjct: 1005 REEREKRRRQEWERQYRKKDELQQEEEQLLREEREKRRLQERERQYREEEELQQEEEQLL 1064 Query: 158 EVEKVRAKKKEAEEEYRNSMPASSFQQQKLRVCEVCSAYLGLHDNDRRLADHFGGKLHLG 217 E+ +++E E +YR ++Q LR + ++R Sbjct: 1065 GEERETRRRQELERQYRKEEELQQEEEQLLR-----------EEPEKRRR---------- 1103 Query: 218 FIQIREKLDQLRKTVAEKQEK--RNQDRLRRREEREREERLSRRSGSRTRDRRRSRSRDR 275 Q RE+ + + + +++E+ R + RRR+E ER+ R R R Sbjct: 1104 --QERERQCREEEELQQEEEQLLREEREKRRRQELERQYREEEEVQQEEEQLLREEPEKR 1161 Query: 276 RRRRSRSTSRERRKLSRSRSR----DRHRRHRSRSRSHSRGHRRASRDRSAKYK 325 RR+ RE +L + + ++ +R + R R + + R +Y+ Sbjct: 1162 RRQELERQYREEEELQQEEEQLLREEQEKRRQERERQYREEEELQRQKRKQRYR 1215 Score = 44.7 bits (104), Expect = 1e-04 Identities = 49/226 (21%), Positives = 94/226 (41%), Gaps = 24/226 (10%) Query: 99 RRTELAKKRLAETQEEISAEVSAKAEKVHELNEEIGKLLAKAEQLGAEGNVDESQKILME 158 RR E +K L E Q+ E+ K + +L +E + EQL + E + ++E Sbjct: 1701 RRQERERKFLQEEQQLRRQELERKFREEEQLRQE-----TEQEQLRRQ----ERYRKILE 1751 Query: 159 VEKVRAKKKEAEEEYRNSMPASSFQQQKLRVCEVCSAYLGLHDNDRRLADHFGGKLHLGF 218 E++R +++E ++ R F++++ E L ++DR+ + + Sbjct: 1752 EEQLRPEREE--QQLRRQERDRKFREEEQLRQEREEQQLRSQESDRKFREEEQLRQEREE 1809 Query: 219 IQIREKL---------DQLRKTVAEKQEKRNQDRLRRREEREREERLSRRSGSRTRDRRR 269 Q+R + +QL+ E++ ++ +DR R EE+ + SRR Sbjct: 1810 QQLRPQQRDGKYRWEEEQLQLEEQEQRLRQERDRQYRAEEQFATQEKSRREEQELWQEEE 1869 Query: 270 SRSRDRRRRRSRSTSRERRKLSRSRSRDRHRRHRSRSRSHSRGHRR 315 + R R R+ R R++ + RHR+ +GH R Sbjct: 1870 QKRRQERERKLREEHIRRQQ----KEEQRHRQVGEIKSQEGKGHGR 1911 Score = 43.9 bits (102), Expect = 2e-04 Identities = 49/228 (21%), Positives = 86/228 (37%), Gaps = 46/228 (20%) Query: 99 RRTELAKKRLAETQEEISAEVSAKAEKVHELNEEIGKLLAKAEQ---LGAEGNVDESQKI 155 R T AK L QE++ E E+ EL E + + EQ E + + ++ Sbjct: 886 RHTLYAKPAL---QEQLRKEQQLLQEEEEELQREEREKRRRQEQERQYREEEQLQQEEEQ 942 Query: 156 LMEVEKVRAKKKEAEEEYRNSMPASSFQQQKLRVCEVCSAYLGLHDNDRRLADHFGGKLH 215 L+ E+ + +++E E +YR ++Q L Sbjct: 943 LLREEREKRRRQERERQYRKDKKLQQKEEQLLG--------------------------- 975 Query: 216 LGFIQIREKLDQLRKTVAEKQEKRNQDRLRRREEREREERLSRRSGSRTRDRRRSRSRDR 275 E+ ++ R+ EK+ + ++ + E+ REER RR R R+ R +D Sbjct: 976 -------EEPEKRRRQEREKKYREEEELQQEEEQLLREEREKRR---RQEWERQYRKKDE 1025 Query: 276 RRRRSRSTSRERRKLSRSRSRDRHRRHRSRSRSHSR---GHRRASRDR 320 ++ RE R+ R + R+R R + G R +R R Sbjct: 1026 LQQEEEQLLREEREKRRLQERERQYREEEELQQEEEQLLGEERETRRR 1073 Score = 43.9 bits (102), Expect = 2e-04 Identities = 58/264 (21%), Positives = 114/264 (43%), Gaps = 35/264 (13%) Query: 68 RADYEIASKERDLFFELDAMDHLES---FIAECDR--RTELAKKRLAETQEEISAEVSAK 122 R + + +ERD F + + H E F+ E R R E +K L E Q+ Sbjct: 1348 REEQPLRRQERDRKFREEELRHQEQGRKFLEEEQRLRRQERERKFLKEEQQ------LRC 1401 Query: 123 AEKVHELNEEIGKLLAKAEQLGAEGNVDESQKILMEVEKVRAKKKEAEEEYRNSMPASSF 182 E+ +L ++ + + EQ + D +K E ++VR ++E E ++ Sbjct: 1402 QEREQQLRQDRDRKFREEEQQLSRQERD--RKFREEEQQVR--RQERERKFLE------- 1450 Query: 183 QQQKLRVCEVCSAYLGLHDNDRRLADHFGGKLHLGFIQIREKLDQLRKTVAEKQEKRNQD 242 ++Q+LR + + ++ L + +LH R++ D RK + E+Q+ R Q+ Sbjct: 1451 EEQQLRQ----ERHRKFREEEQLLQEREEQQLH------RQERD--RKFLEEEQQLRRQE 1498 Query: 243 RLRR-REEREREERLSRRSGSRTRDRRRSRSRDRRRRRSRSTSRERRKLSRSRSRDRHRR 301 R R+ RE+ R + R+ + R + + + + + R+ R R + RDR R Sbjct: 1499 RDRKFREQELRSQEPERKFLEEEQQLHRQQRQRKFLQEEQQLRRQERGQQRRQDRDRKFR 1558 Query: 302 HRSRSRSHSRGHRRASRDRSAKYK 325 + R + + ++R K++ Sbjct: 1559 EEEQLRQEREEQQLSRQERDRKFR 1582 Score = 43.5 bits (101), Expect = 3e-04 Identities = 47/202 (23%), Positives = 86/202 (42%), Gaps = 19/202 (9%) Query: 139 KAEQLGAEGNVDESQKILMEVEKV---RAKKKEAEEEYRNSMPASSFQQQKLRVCEVCSA 195 + QL AE Q+ L E E+ R +++E E+E + Q+++ R ++ Sbjct: 794 RERQLRAEERQQREQRFLPEEEEKEQRRRQRREREKELQFLEEEEQLQRRE-RAQQLQEE 852 Query: 196 YLGLHDNDRRLADHFGGKLHLGFIQIREKLDQLRKTVAEK----QEKRNQDRLRRREERE 251 GL ++ R + Q+ E+ + R T+ K ++ R + +L + EE E Sbjct: 853 EDGLQEDQERRRSQEQRRDQKWRWQLEEERKRRRHTLYAKPALQEQLRKEQQLLQEEEEE 912 Query: 252 --REERLSRRSGSRTRDRRRSRSRDRRRRRSRSTSRERRKLSRSRSRDRHRRHRSRSRSH 309 REER RR R R+ R ++ ++ RE R+ R + R+R R + + Sbjct: 913 LQREEREKRR---RQEQERQYREEEQLQQEEEQLLREEREKRRRQERERQYRKDKKLQQK 969 Query: 310 ------SRGHRRASRDRSAKYK 325 +R ++R KY+ Sbjct: 970 EEQLLGEEPEKRRRQEREKKYR 991 Score = 43.5 bits (101), Expect = 3e-04 Identities = 43/206 (20%), Positives = 87/206 (42%), Gaps = 16/206 (7%) Query: 102 ELAKKRLAETQEEISAEVSAKAEKVHELNEEIGKLLAKA--EQLGAEGNVDESQKILMEV 159 E K+R E +++ E + E+ L EE K + Q + + + ++ L+ Sbjct: 977 EPEKRRRQEREKKYREEEELQQEEEQLLREEREKRRRQEWERQYRKKDELQQEEEQLLRE 1036 Query: 160 EKVRAKKKEAEEEYRNSMPASSFQQQKLRVCEVCSAYLGLHDNDRRLADHFGGKLHLGFI 219 E+ + + +E E +YR ++Q LG RR + + + Sbjct: 1037 EREKRRLQERERQYREEEELQQEEEQ----------LLGEERETRRRQEL--ERQYRKEE 1084 Query: 220 QIREKLDQLRKTVAEKQEKRNQDRLRRREEREREERLSRRSGSRTRDRRRSRSRDRRRRR 279 +++++ +QL + EK +R Q+R R+ E E ++ + R++RR + +R+ R Sbjct: 1085 ELQQEEEQLLREEPEK--RRRQERERQCREEEELQQEEEQLLREEREKRRRQELERQYRE 1142 Query: 280 SRSTSRERRKLSRSRSRDRHRRHRSR 305 +E +L R R R+ R Sbjct: 1143 EEEVQQEEEQLLREEPEKRRRQELER 1168 Score = 43.5 bits (101), Expect = 3e-04 Identities = 54/253 (21%), Positives = 109/253 (43%), Gaps = 49/253 (19%) Query: 99 RRTELAKKRLAETQEEISAEVSAKAEKVHELN----EEIGKLLAKAEQLGAEGNVDESQK 154 R+ E ++ R ++Q+++ + + E+ E ++ + + EQL E + ++ Sbjct: 1251 RQLEDSQLRDRQSQQDLQHLLGEQQERDREQERRRWQQRDRHFPEEEQLEREEQKEAKRR 1310 Query: 155 ILMEVEKVRAKKKEAEEEYRNSMPASSFQQQKLRVCEVCSAYLGLHDNDRRLADHFGGKL 214 E+ + ++E EE+ R F++++ + E L + DR+ + Sbjct: 1311 DRKSQEEKQLLREEREEKRRRQETDRKFREEEQLLQEREEQPLRRQERDRKFREE----- 1365 Query: 215 HLGFIQIREKLDQLRKTVAEKQEKRNQDRLRRREE-------------REREERLSRRSG 261 ++R + +Q RK + E+Q RLRR+E +ERE++L + Sbjct: 1366 -----ELRHQ-EQGRKFLEEEQ------RLRRQERERKFLKEEQQLRCQEREQQLRQDRD 1413 Query: 262 SRTRDRRRSRSRDRRRRRSRSTSRERRKLSRSRS---------RDRHRRHRS-----RSR 307 + R+ + SR R R+ R ++ R+ R R ++RHR+ R + R Sbjct: 1414 RKFREEEQQLSRQERDRKFREEEQQVRRQERERKFLEEEQQLRQERHRKFREEEQLLQER 1473 Query: 308 SHSRGHRRASRDR 320 + HR+ RDR Sbjct: 1474 EEQQLHRQ-ERDR 1485 Score = 42.7 bits (99), Expect = 4e-04 Identities = 49/240 (20%), Positives = 104/240 (43%), Gaps = 10/240 (4%) Query: 69 ADYEIASKERDLFFELDAMDHLESFIAECDRRTELAKKRLAETQEEISAEVSAKAEKVHE 128 A+ E S++++ + D E + E ++R E Q + S K + E Sbjct: 149 AEGEEQSEKQERLEQRDRQRRDEELWRQRQEWQEREERRAEEEQLQ-----SCKGHETEE 203 Query: 129 LNEEIGKLLAKAEQLGAEGNVDESQKILMEVEKVRAKKKEAEEEYRNSMPASSFQQQKLR 188 +E + +L +G ++ Q+ + R ++E E+E+R +++KL+ Sbjct: 204 FPDEEQLRRRELLELRRKGREEKQQQ--RRERQDRVFQEEEEKEWRKRETVLRKEEEKLQ 261 Query: 189 VCEVCSAYLGLHDNDRRLADHFGGKLHLGFIQIREKLDQLRKTVAEKQEKRNQDRLRRRE 248 E L + + +L +L + ++ +LR+ + + K+ ++R ++E Sbjct: 262 E-EEPQRQRELQEEEEQLRKLERQELRRERQEEEQQQQRLRRE-QQLRRKQEEERREQQE 319 Query: 249 E-REREERLSRRSGSRTRDRRRSRSRDRRRRRSRSTSRERRKLSRSRSRDRHRRHRSRSR 307 E RE++ER ++ R + RR + R ++ R ERR+ R ++ RR + R Sbjct: 320 ERREQQERREQQEERREQQLRREQEERREQQLRREQEEERREQQLRREQEEERREQQLRR 379 Score = 42.7 bits (99), Expect = 4e-04 Identities = 55/234 (23%), Positives = 97/234 (41%), Gaps = 19/234 (8%) Query: 100 RTELAKKRLAETQEEISAEVSAK-AEKVHELNEEIGKLLAKAEQLGAEGNVDESQKILME 158 R E +K L E Q+ E K E+ E K L + +QL + +K L E Sbjct: 1480 RQERDRKFLEEEQQLRRQERDRKFREQELRSQEPERKFLEEEQQLHRQ---QRQRKFLQE 1536 Query: 159 VEKVRAKKKEAEEEYRNSMPASSFQQQKLRVCEVCSAYLGLHDNDRRLA-DHFGGKLHLG 217 +++R ++E ++ R ++++LR E L + DR+ + + Sbjct: 1537 EQQLR--RQERGQQRRQDRDRKFREEEQLRQ-EREEQQLSRQERDRKFRLEEQKVRRQEQ 1593 Query: 218 FIQIREKLDQLRKTVAEKQEKRNQDRLRRREEREREERLSRRSGSRTRD----------R 267 + E QLR+ ++Q ++ +DR R +E+ +ER ++ + RD R Sbjct: 1594 ERKFMEDEQQLRRQEGQQQLRQERDRKFREDEQLLQEREEQQLHRQERDRKFLEEEPQLR 1653 Query: 268 RRSRSRDRRRRRSRSTSRERRKLSRSRSRDRHRRHRSRS-RSHSRGHRRASRDR 320 R+ R + R R R E + L + R+ R R R + RR R+R Sbjct: 1654 RQEREQQLRHDRDRKFREEEQLLQEGEEQQLRRQERDRKFREEEQQLRRQERER 1707 Score = 41.2 bits (95), Expect = 0.001 Identities = 51/236 (21%), Positives = 97/236 (41%), Gaps = 25/236 (10%) Query: 96 ECDRRTELAKKRLAETQEEISAEVSAKAEKVHELNEEIGKLLA-----KAEQLGAEGNVD 150 E +RR + R +E++ E +A++ ++E +LL K + + Sbjct: 1280 EQERRRWQQRDRHFPEEEQLEREEQKEAKRRDRKSQEEKQLLREEREEKRRRQETDRKFR 1339 Query: 151 ESQKILMEVEKVRAKKKEA-----EEEYRNSMPASSFQQQKLRVCEVCSAYLGLHDNDRR 205 E +++L E E+ +++E EEE R+ F +++ R L + +R+ Sbjct: 1340 EEEQLLQEREEQPLRRQERDRKFREEELRHQEQGRKFLEEEQR--------LRRQERERK 1391 Query: 206 LADHFGGKLHLGFIQIREKLDQLRKTVAEKQEKRNQDRLRRREEREREERLSRRSGSRTR 265 +L + + + D+ RK E+Q+ Q+R R+ E E++ R R Sbjct: 1392 FLKE-EQQLRCQEREQQLRQDRDRKFREEEQQLSRQERDRKFREEEQQVRRQERERKFLE 1450 Query: 266 DRRRSRSRDRRRRRSRSTSRERRKLSRSRSRDRHRRHRSRS-RSHSRGHRRASRDR 320 + ++ R+ R R E + L + HR+ R R + RR RDR Sbjct: 1451 EEQQ-----LRQERHRKFREEEQLLQEREEQQLHRQERDRKFLEEEQQLRRQERDR 1501 Score = 40.8 bits (94), Expect = 0.002 Identities = 47/233 (20%), Positives = 84/233 (36%), Gaps = 30/233 (12%) Query: 98 DRRTELAKKRLAETQEEISAEVSAKAEKVHELNEEIGKLLAKAE-QLGAEGNVDESQKIL 156 + E ++RL EE E E+ + E I + K + QL +E + +S K+ Sbjct: 662 EEEEERLEQRLKREHEEERREQELAEEEQEQARERIKSRIPKWQWQLESEADARQS-KVY 720 Query: 157 MEVEKVRAKKKEAEEEYRNSMPASSFQQQKLRVCEVCSAYLGLHDNDRRLADHFGGKLHL 216 K +++ E+E + S Q Q+ + H Sbjct: 721 SRPRKQEGQRRRQEQEEKRRRRESELQWQEEE------------------------RAHR 756 Query: 217 GFIQIREKLDQLRKTVAEKQEKRNQDRLRRR----EEREREERLSRRSGSRTRDRRRSRS 272 + ++ D + AE++ +R + RL R E+RER+ R R R Sbjct: 757 QQQEEEQRRDFTWQWQAEEKSERGRQRLSARPPLREQRERQLRAEERQQREQRFLPEEEE 816 Query: 273 RDRRRRRSRSTSRERRKLSRSRSRDRHRRHRSRSRSHSRGHRRASRDRSAKYK 325 +++RRR+ R +E + L R R + R RS + + Sbjct: 817 KEQRRRQRREREKELQFLEEEEQLQRRERAQQLQEEEDGLQEDQERRRSQEQR 869 Score = 40.4 bits (93), Expect = 0.002 Identities = 28/103 (27%), Positives = 47/103 (45%), Gaps = 12/103 (11%) Query: 225 LDQLRKTVAEKQEKRNQDRLRRREERE---REERLSRRSGSRTRDRRRSRSRDRRRRRSR 281 LD+ ++ + +E QDR + ++R R+ +L G R R +R+ + R+ + Sbjct: 95 LDEEKRARCDGKESLLQDRRQEEDQRRFEPRDRQLEEEPGQRRRQKRQEQERELAEGEEQ 154 Query: 282 STSRERRKLSRSRSRDRHRRH----RSRSRSHSRGHRRASRDR 320 S +ER + RDR RR R R R RRA ++ Sbjct: 155 SEKQERLE-----QRDRQRRDEELWRQRQEWQEREERRAEEEQ 192 Score = 39.3 bits (90), Expect = 0.005 Identities = 25/104 (24%), Positives = 48/104 (46%), Gaps = 1/104 (0%) Query: 222 REKLDQLRKTVAEKQEKRNQDRLRRREEREREERLSRRSGSRTRDRRRSRSRDRRRRRSR 281 +E+ LR+ EK+ ++ DR R EE+ +ER + + RDR+ R + + R Sbjct: 1315 QEEKQLLREEREEKRRRQETDRKFREEEQLLQEREEQPLRRQERDRKFREEELRHQEQGR 1374 Query: 282 STSRERRKLSRSRSRDRHRRHRSRSRSHSRGHRRASRDRSAKYK 325 E ++L R + + + R R ++ +DR K++ Sbjct: 1375 KFLEEEQRLRRQERERKFLKEEQQLRCQER-EQQLRQDRDRKFR 1417 Score = 38.5 bits (88), Expect = 0.008 Identities = 21/106 (19%), Positives = 50/106 (47%), Gaps = 3/106 (2%) Query: 221 IREKLDQLRKTVAEKQEKRNQDRLRRREEREREERLSRRSGSRTRDRRRSRSRDRRRRRS 280 ++E+ ++L++ EK+ ++ Q+R R EE+ ++E R + RR+ R R R+ + Sbjct: 906 LQEEEEELQREEREKRRRQEQERQYREEEQLQQEEEQLLREEREKRRRQERERQYRKDKK 965 Query: 281 RSTSRER---RKLSRSRSRDRHRRHRSRSRSHSRGHRRASRDRSAK 323 E+ + + R ++R +++R + +R + Sbjct: 966 LQQKEEQLLGEEPEKRRRQEREKKYREEEELQQEEEQLLREEREKR 1011 Score = 37.7 bits (86), Expect = 0.014 Identities = 51/262 (19%), Positives = 102/262 (38%), Gaps = 58/262 (22%) Query: 96 ECDRRTELAKKRLAETQEEISAEVSAKAEKVHELNEEIGKLLAKAEQLGAEGNVDESQKI 155 E ++R ++R E Q E + E+ +L EE E + E Q+ Sbjct: 816 EKEQRRRQRREREKELQFLEEEEQLQRRERAQQLQEE-------------EDGLQEDQER 862 Query: 156 LMEVEKVRAKK-----KEAEEEYRNSMPASSFQQQKLRVCEVCSAYLGLHDNDRRLADHF 210 E+ R +K +E + R+++ A Q++LR +++L Sbjct: 863 RRSQEQRRDQKWRWQLEEERKRRRHTLYAKPALQEQLR-------------KEQQLLQEE 909 Query: 211 GGKLHLGFIQIREKLDQLRKTVAEKQEKRNQDRL-------RRREEREREERLSRRSGSR 263 +L + R + +Q R+ E+Q ++ +++L RRR+ERER+ R ++ + Sbjct: 910 EEELQREEREKRRRQEQERQYREEEQLQQEEEQLLREEREKRRRQERERQYRKDKKLQQK 969 Query: 264 TR-------DRRRSRSRDRRRRRSRSTSRERRKLSRSRSRDRHRRHRSRSRS-------- 308 ++RR + R+++ R +E +L R R R+ R Sbjct: 970 EEQLLGEEPEKRRRQEREKKYREEEELQQEEEQLLREEREKRRRQEWERQYRKKDELQQE 1029 Query: 309 -----HSRGHRRASRDRSAKYK 325 +R ++R +Y+ Sbjct: 1030 EEQLLREEREKRRLQERERQYR 1051 Score = 37.7 bits (86), Expect = 0.014 Identities = 55/251 (21%), Positives = 103/251 (41%), Gaps = 32/251 (12%) Query: 70 DYEIASKERDLFF-----ELDAMDHLESFIAECD--RRTELAKKRLAETQ--EEISAEVS 120 + ++ +ERD F +L + F+ E RR EL +K E Q +E E Sbjct: 1681 EQQLRRQERDRKFREEEQQLRRQERERKFLQEEQQLRRQELERKFREEEQLRQETEQEQL 1740 Query: 121 AKAEKVHELNEEIGKLLAKAEQLGAEGNVD----ESQKILMEVEKVRAKKKEAEEEYRNS 176 + E+ ++ EE + EQ D E +++ E E+ + + +E++ ++R Sbjct: 1741 RRQERYRKILEEEQLRPEREEQQLRRQERDRKFREEEQLRQEREEQQLRSQESDRKFREE 1800 Query: 177 MPA-SSFQQQKLRVCEVCSAY------LGLHDNDRRLADHFGGKLHLGFIQIREKLDQLR 229 ++Q+LR + Y L L + ++RL + + E+ Sbjct: 1801 EQLRQEREEQQLRPQQRDGKYRWEEEQLQLEEQEQRLRQERDRQY-----RAEEQFATQE 1855 Query: 230 KTVAEKQEKRNQDRLRRREEREREERLSRRSGSRTRDRRRSRSRDRRRRRSRSTSRERRK 289 K+ E+QE ++ +RR+ERER+ R RR+ + R R+ S+E + Sbjct: 1856 KSRREEQELWQEEEQKRRQERERKLR-------EEHIRRQQKEEQRHRQVGEIKSQEGKG 1908 Query: 290 LSRSRSRDRHR 300 R H+ Sbjct: 1909 HGRLLEPGTHQ 1919 Score = 35.4 bits (80), Expect = 0.070 Identities = 25/99 (25%), Positives = 45/99 (45%), Gaps = 9/99 (9%) Query: 222 REKLDQLRKTVAEKQEK-RNQDRLRRREEREREERLSR-RSGSRTRDRRRSRSRDRRRRR 279 R+K + + +AE +E+ Q+RL +R+ + R+E L R R + R+ RR+ + + Sbjct: 138 RQKRQEQERELAEGEEQSEKQERLEQRDRQRRDEELWRQRQEWQEREERRAEEEQLQSCK 197 Query: 280 SRSTSR-------ERRKLSRSRSRDRHRRHRSRSRSHSR 311 T RR+L R + R + + R R Sbjct: 198 GHETEEFPDEEQLRRRELLELRRKGREEKQQQRRERQDR 236 Score = 32.3 bits (72), Expect = 0.59 Identities = 26/112 (23%), Positives = 46/112 (41%), Gaps = 6/112 (5%) Query: 198 GLHDNDRRLADHFGGKLHLGFIQIREKLDQLRKTVAEKQEKRNQDRLRRREEREREERLS 257 GL + R D GK L +Q R + + R+ ++ + RRR++R+ +ER Sbjct: 94 GLDEEKRARCD---GKESL--LQDRRQEEDQRRFEPRDRQLEEEPGQRRRQKRQEQEREL 148 Query: 258 RRSGSRTRDRRRSRSRDRRRRRSRSTSRERRKLSRSRSRDRHRRHRSRSRSH 309 ++ + R RD R+RR R+R++ R + H Sbjct: 149 AEGEEQSEKQERLEQRD-RQRRDEELWRQRQEWQEREERRAEEEQLQSCKGH 199 >gi|62460633 RNA-binding motif protein 16 [Homo sapiens] Length = 1271 Score = 61.6 bits (148), Expect = 9e-10 Identities = 36/85 (42%), Positives = 51/85 (60%), Gaps = 1/85 (1%) Query: 241 QDRLRRREEREREERLSRRSGSRTRDRRRSRSRDRRRRRSRSTSRERRKLSRSRSRDRHR 300 QD + + ++++ RS SRT R RSRS +RR RSRS SR+R+ RSRSR R R Sbjct: 379 QDGVEEEVFEQEAKKVAVRSRSRTHSRSRSRSPRKRRSRSRSGSRKRKHRKRSRSRSRER 438 Query: 301 RHRSRSRSHSRGHRRASRDRSAKYK 325 + +S SRS+S R R++ + K Sbjct: 439 KRKS-SRSYSSERRAREREKERQKK 462 Score = 58.2 bits (139), Expect = 1e-08 Identities = 72/269 (26%), Positives = 108/269 (40%), Gaps = 30/269 (11%) Query: 50 AGTRMDLGECTKIHDLALRADYEIASKERDLFFELDAMDHLESFIAECDRRTELAKKRLA 109 AG + L T A A + E+ + F MD + E +E KK + Sbjct: 227 AGLVVQLQALTAQLTAAAAAANTLTPLEQGVSFNKKLMDRFD--FGEDSEHSEEPKKEIP 284 Query: 110 ETQEEISAEVSAKAEKVHELNEEIGKLLAKAEQLGAEGNVDESQKILMEVEKVRAKKKEA 169 +Q +E S H++ AEQL + Q++L + + +A +++ Sbjct: 285 ASQLSHVSE-SVNNSIFHQI----------AEQLQQQNLEHLRQQLLEQQQPQKATPQDS 333 Query: 170 EE-----EYRNSMPASSFQQQKLRVCEVCSAYLGLHDNDRRLADHFGGKLHLGFIQIREK 224 +E E+ S S QQ L + + D + + G E Sbjct: 334 QEGTFGSEHSASPSQGSSQQHFLEPEVNLDDSIDIQQQDMDIDEGQDGVEE-------EV 386 Query: 225 LDQLRKTVAEKQEKRNQDRLRRREEREREERLSRRSGSRTRDRR---RSRSRDRRRRRSR 281 +Q K VA + R R R R R+R R RSGSR R R RSRSR+R+R+ SR Sbjct: 387 FEQEAKKVAVRSRSRTHSRSRSRSPRKRRSR--SRSGSRKRKHRKRSRSRSRERKRKSSR 444 Query: 282 STSRERRKLSRSRSRDRHRRHRSRSRSHS 310 S S ERR R + R + RS++ S Sbjct: 445 SYSSERRAREREKERQKKGLPPIRSKTLS 473 >gi|7662238 apoptotic chromatin condensation inducer 1 [Homo sapiens] Length = 1341 Score = 61.2 bits (147), Expect = 1e-09 Identities = 49/169 (28%), Positives = 78/169 (46%), Gaps = 26/169 (15%) Query: 160 EKVRAKKKEAEEEYRNSMPASSFQQQKLRVCEVCSAYLGLHDNDRRLADHFGGKLHLGFI 219 EK KK++A+EE + F++ K C +L L D+ Sbjct: 1193 EKKSEKKEKAQEEPPAKLLDDLFRKTK---AAPCIYWLPLTDS----------------- 1232 Query: 220 QIREKLDQLRKTVAEKQEKRNQDRLRRREEREREERLSRRSGSRTRDRRRSRSRDRRRRR 279 QI +K + + E++++R + ++ERE+E R+ R++RR SR+R R R Sbjct: 1233 QIVQKEAERAERAKEREKRRKEQEEEEQKEREKEAE-RERNRQLEREKRREHSRERDRER 1291 Query: 280 SRSTSRERRKLSRSRSRDRHR---RHRSRSRSHSRGHRRAS--RDRSAK 323 R R+R R R RDR R R R ++ HSR R++ RDR + Sbjct: 1292 ERERERDRGDRDRDRERDRERGRERDRRDTKRHSRSRSRSTPVRDRGGR 1340 Score = 48.9 bits (115), Expect = 6e-06 Identities = 33/79 (41%), Positives = 40/79 (50%), Gaps = 2/79 (2%) Query: 222 REK-LDQLRKTVAEKQEKRNQDRLRRRE-EREREERLSRRSGSRTRDRRRSRSRDRRRRR 279 REK ++ R E++++R R R RE ERERE R R RDR R R RDRR + Sbjct: 1263 REKEAERERNRQLEREKRREHSRERDRERERERERDRGDRDRDRERDRERGRERDRRDTK 1322 Query: 280 SRSTSRERRKLSRSRSRDR 298 S SR R R R R Sbjct: 1323 RHSRSRSRSTPVRDRGGRR 1341 Score = 47.4 bits (111), Expect = 2e-05 Identities = 30/85 (35%), Positives = 43/85 (50%), Gaps = 7/85 (8%) Query: 223 EKLDQLRKTVAEKQEKRNQDRLRRRE-------EREREERLSRRSGSRTRDRRRSRSRDR 275 E+ + R+ AE++ R +R +RRE ERERE R R R+R R R R+R Sbjct: 1257 EEEQKEREKEAERERNRQLEREKRREHSRERDRERERERERDRGDRDRDRERDRERGRER 1316 Query: 276 RRRRSRSTSRERRKLSRSRSRDRHR 300 RR ++ SR R + + R R R Sbjct: 1317 DRRDTKRHSRSRSRSTPVRDRGGRR 1341 Score = 43.5 bits (101), Expect = 3e-04 Identities = 31/90 (34%), Positives = 45/90 (50%), Gaps = 13/90 (14%) Query: 235 KQEKRNQDRLRRREEREREERLSRRSGSRTRDRRRSRSRDRRRRRSRSTSRERRKLSRSR 294 + E+R Q+R R + ERE + RR +R+ R RD+ R RS RSR Sbjct: 1132 RAEQREQERAVREQWAEREREMERRERTRSE---REWDRDKVREGPRS---------RSR 1179 Query: 295 SRDRHRRHRSRSR-SHSRGHRRASRDRSAK 323 SRDR R+ R++S+ S +A + AK Sbjct: 1180 SRDRRRKERAKSKEKKSEKKEKAQEEPPAK 1209 Score = 42.4 bits (98), Expect = 6e-04 Identities = 26/70 (37%), Positives = 36/70 (51%), Gaps = 5/70 (7%) Query: 260 SGSRTRDRRRSRSRDRRRRRSRSTSRERRKLSRSRSRDRHRRHRSRSRSHSRGHRRA--- 316 SGSR+ RS+ RD + R+ + R R K+ + + R RSRSRS S R++ Sbjct: 599 SGSRSHSPLRSKQRDVAQARTHANPRGRPKMGSRSTSESRSRSRSRSRSASSNSRKSLSP 658 Query: 317 --SRDRSAKY 324 SRD S Y Sbjct: 659 GVSRDSSTSY 668 Score = 42.0 bits (97), Expect = 7e-04 Identities = 24/74 (32%), Positives = 42/74 (56%), Gaps = 1/74 (1%) Query: 224 KLDQLRKTVAEKQEKRNQDRLRRREEREREERLSRRSGSRTRDRRRSRSRDRRRRRSRST 283 + +Q + A +++ ++R R ER R ER R R R RSRSRD RRR+ R+ Sbjct: 1132 RAEQREQERAVREQWAEREREMERRERTRSEREWDRDKVREGPRSRSRSRD-RRRKERAK 1190 Query: 284 SRERRKLSRSRSRD 297 S+E++ + ++++ Sbjct: 1191 SKEKKSEKKEKAQE 1204 Score = 37.4 bits (85), Expect = 0.018 Identities = 39/155 (25%), Positives = 48/155 (30%), Gaps = 65/155 (41%) Query: 229 RKTVAEKQEKRNQDRLRRREER-------------------------------------- 250 R V E R++ R RRR+ER Sbjct: 1167 RDKVREGPRSRSRSRDRRRKERAKSKEKKSEKKEKAQEEPPAKLLDDLFRKTKAAPCIYW 1226 Query: 251 -------------EREERLSRRSGSRTR-------------DRRRSRSRDRRRRRSRSTS 284 ER ER R R +R R+R +R +RR S Sbjct: 1227 LPLTDSQIVQKEAERAERAKEREKRRKEQEEEEQKEREKEAERERNRQLEREKRREHSRE 1286 Query: 285 RERRKLSRSRSRDRHRRHRSRSRSHSRGHRRASRD 319 R+R + R R RDR R R R R RG R RD Sbjct: 1287 RDRER-ERERERDRGDRDRDRERDRERGRERDRRD 1320 Score = 33.5 bits (75), Expect = 0.26 Identities = 21/70 (30%), Positives = 38/70 (54%), Gaps = 2/70 (2%) Query: 222 REKLDQLRKTVAEKQ-EKRNQDRLRRREEREREE-RLSRRSGSRTRDRRRSRSRDRRRRR 279 RE+ +R+ AE++ E ++R R E +R++ R RS SR+RDRRR + ++ Sbjct: 1136 REQERAVREQWAEREREMERRERTRSEREWDRDKVREGPRSRSRSRDRRRKERAKSKEKK 1195 Query: 280 SRSTSRERRK 289 S + + + Sbjct: 1196 SEKKEKAQEE 1205 >gi|6631100 natural killer-tumor recognition sequence [Homo sapiens] Length = 1462 Score = 61.2 bits (147), Expect = 1e-09 Identities = 42/110 (38%), Positives = 57/110 (51%), Gaps = 14/110 (12%) Query: 226 DQLRKTVAEKQEKRNQDRLRRREEREREERLSRRSGSRTRDRRRSRSRDRRRRRSRSTSR 285 D++RKT + RNQ+ + R++ RS SR+R + ++SR R R S S SR Sbjct: 1279 DEVRKTARLNRRPRNQESSSDEQTPSRDDDSQSRSPSRSRSKSETKSRHRTRSVSYSHSR 1338 Query: 286 ER----------RKLSRSRSRDRHRRHRSRSRSHS----RGHRRASRDRS 321 R R SRSRSR + R R+RSRS S + HR +SR RS Sbjct: 1339 SRSRSSTSSYRSRSYSRSRSRGWYSRGRTRSRSSSYRSYKSHRTSSRSRS 1388 Score = 43.9 bits (102), Expect = 2e-04 Identities = 40/115 (34%), Positives = 56/115 (48%), Gaps = 6/115 (5%) Query: 215 HLGFIQIREKLDQLRKTVAE----KQEKRNQ-DRLRRREEREREERLSRRSGSRT-RDRR 268 HL IQ L +++T + K+EK ++ D+ + +R S RS SR+ R R Sbjct: 642 HLLPIQSTYSLANIKETGSSSSYHKREKNSESDQSTYSKYSDRSSESSPRSRSRSSRSRS 701 Query: 269 RSRSRDRRRRRSRSTSRERRKLSRSRSRDRHRRHRSRSRSHSRGHRRASRDRSAK 323 SRS R R + S SR R SRS SR+++ H SRS S + R AK Sbjct: 702 YSRSYTRSRSLASSHSRSRSPSSRSHSRNKYSDHSQCSRSSSYTSISSDDGRRAK 756 Score = 38.9 bits (89), Expect = 0.006 Identities = 33/97 (34%), Positives = 44/97 (45%), Gaps = 12/97 (12%) Query: 239 RNQDRLRRREEREREERLSRRSGSRTRDRRRSRSRDRR---------RRRSRSTSRERRK 289 R++ R R R SR G +R R RSRS R R RSRS+S + Sbjct: 1338 RSRSRSSTSSYRSRSYSRSRSRGWYSRGRTRSRSSSYRSYKSHRTSSRSRSRSSSYDPHS 1397 Query: 290 LSRSRSRDRH---RRHRSRSRSHSRGHRRASRDRSAK 323 SRS + D + R RSRS+ HR S +R ++ Sbjct: 1398 RSRSYTYDSYYSRSRSRSRSQRSDSYHRGRSYNRRSR 1434 Score = 37.7 bits (86), Expect = 0.014 Identities = 36/101 (35%), Positives = 49/101 (48%), Gaps = 18/101 (17%) Query: 235 KQEKRNQDRLRRREEREREERLSRRSGSRTRDRRRSRS------------RDRRRRRSRS 282 + K + R++ +RER R S S + R S+S RD R +S S Sbjct: 466 ESSKSSTRRMKSSCDRERSSRSSSLSSHHSSKRDWSKSDKDVQSSLTHSSRDSYRSKSHS 525 Query: 283 TSRERRKLSRSRSRDR---HRRHRSRSRSHSR-GHR-RASR 318 S R SRSR+ + H R RS+SRS S+ GHR RAS+ Sbjct: 526 QSYSRGS-SRSRTASKSSSHSRSRSKSRSSSKSGHRKRASK 565 Score = 37.7 bits (86), Expect = 0.014 Identities = 35/97 (36%), Positives = 42/97 (43%), Gaps = 17/97 (17%) Query: 239 RNQDRLRRREERE-REERLSRRSGSRT-----RDRRRSRSRDRRRRRSRSTSRERRKLSR 292 R + R R R + R S RS SR+ R RS + D RSRS SR +R S Sbjct: 1364 RGRTRSRSSSYRSYKSHRTSSRSRSRSSSYDPHSRSRSYTYDSYYSRSRSRSRSQRSDSY 1423 Query: 293 SRSRDRHRRHRS-----------RSRSHSRGHRRASR 318 R R +RR RS RS SH R +SR Sbjct: 1424 HRGRSYNRRSRSCRSYGSDSESDRSYSHHRSPSESSR 1460 Score = 35.8 bits (81), Expect = 0.053 Identities = 47/182 (25%), Positives = 78/182 (42%), Gaps = 28/182 (15%) Query: 158 EVEKVRAKKKEAEEEYRN----SMPASS-FQQQKLRVCEVCSAYLGLHDNDRRLADHFGG 212 E++++RA + + E++ S P SS + ++ L +Y G + +D A H G Sbjct: 368 EMQRLRAYRPPSGEKWSKGDKLSDPCSSRWDERSLSQRSRSWSYNGYY-SDLSTARHSG- 425 Query: 213 KLHLGFIQIREKLDQLRKTVAEKQEKRNQDRLRRREEREREERLS----RRSGSRTRDRR 268 K + K V K++ + Q RR ++ ++ L S S TR + Sbjct: 426 ---------HHKKRRKEKKVKHKKKGKKQKHCRRHKQTKKRRILIPSDIESSKSSTRRMK 476 Query: 269 RSRSRDRRRRRSRSTSRERRKLSRSRSRD-------RHRRHRSRSRSHSRGHRR-ASRDR 320 S R+R R S +S K S+S R RS+SHS+ + R +SR R Sbjct: 477 SSCDRERSSRSSSLSSHHSSKRDWSKSDKDVQSSLTHSSRDSYRSKSHSQSYSRGSSRSR 536 Query: 321 SA 322 +A Sbjct: 537 TA 538 Score = 35.8 bits (81), Expect = 0.053 Identities = 23/52 (44%), Positives = 29/52 (55%), Gaps = 1/52 (1%) Query: 255 RLSRRSGSRTRDRRRSRSRDRRRRRSRSTSRERRKLSRSRSRDRHRRHRSRS 306 R S RS S ++ R SR R +S S SR R K SRS S+ HR+ S+S Sbjct: 516 RDSYRSKSHSQSYSRGSSRSRTASKSSSHSRSRSK-SRSSSKSGHRKRASKS 566 Score = 34.3 bits (77), Expect = 0.16 Identities = 27/78 (34%), Positives = 40/78 (51%), Gaps = 12/78 (15%) Query: 259 RSGSRTRDRRRSRSRDRRRRRSRSTSRER----------RKLSRSRSRDRHR-RHRSRSR 307 R GS + R++ +RR R S+S E+ R SRSRS+ + RHR+RS Sbjct: 1273 RPGSLFDEVRKTARLNRRPRNQESSSDEQTPSRDDDSQSRSPSRSRSKSETKSRHRTRSV 1332 Query: 308 SHSRGHRRASRDRSAKYK 325 S+S R SR ++ Y+ Sbjct: 1333 SYSHSRSR-SRSSTSSYR 1349 Score = 33.9 bits (76), Expect = 0.20 Identities = 29/97 (29%), Positives = 45/97 (46%), Gaps = 6/97 (6%) Query: 231 TVAEKQEKRNQDRLRRREEREREER--LSRRSGSRTRDRRRSRSRDRRRRR-SRSTSRER 287 ++A +E + +RE+ ++ S+ S + RSRSR R R SRS +R R Sbjct: 651 SLANIKETGSSSSYHKREKNSESDQSTYSKYSDRSSESSPRSRSRSSRSRSYSRSYTRSR 710 Query: 288 RKLSRSRSRDRHRRHRSRSRSHSRGHRRASRDRSAKY 324 S + S R R SRS S ++ + RS+ Y Sbjct: 711 ---SLASSHSRSRSPSSRSHSRNKYSDHSQCSRSSSY 744 Score = 33.5 bits (75), Expect = 0.26 Identities = 30/87 (34%), Positives = 38/87 (43%), Gaps = 6/87 (6%) Query: 240 NQDRLRRREEREREERLSRRSGSRTRDRR-----RSRSRDRRRRRSRSTSRERRKLSRSR 294 ++ R R R R + S R+ SR+R R SRSR S SR R + RS Sbjct: 1363 SRGRTRSRSSSYRSYK-SHRTSSRSRSRSSSYDPHSRSRSYTYDSYYSRSRSRSRSQRSD 1421 Query: 295 SRDRHRRHRSRSRSHSRGHRRASRDRS 321 S R R + RSRS + DRS Sbjct: 1422 SYHRGRSYNRRSRSCRSYGSDSESDRS 1448 Score = 30.4 bits (67), Expect = 2.2 Identities = 23/103 (22%), Positives = 37/103 (35%), Gaps = 7/103 (6%) Query: 221 IREKLDQLRKTVAEKQEKRNQDRLRRREEREREERLSRRSGSRTRDRRRSRSRDRRRRRS 280 I++ ++ RK + + E E L +R R R RR + Sbjct: 181 IKDVFEKKRKKPTHSEGSDSSSNSSSSSESSSESELEH-------ERSRRRKHKRRPKVK 233 Query: 281 RSTSRERRKLSRSRSRDRHRRHRSRSRSHSRGHRRASRDRSAK 323 RS R + S R++H + S + + S D SAK Sbjct: 234 RSKKRRKEASSSEEPRNKHAMNPKGHSERSDTNEKRSVDSSAK 276 Score = 29.6 bits (65), Expect = 3.8 Identities = 18/62 (29%), Positives = 28/62 (45%) Query: 230 KTVAEKQEKRNQDRLRRREEREREERLSRRSGSRTRDRRRSRSRDRRRRRSRSTSRERRK 289 K V ++D R + + R S RS + ++ SRSR + R S+S R+R Sbjct: 505 KDVQSSLTHSSRDSYRSKSHSQSYSRGSSRSRTASKSSSHSRSRSKSRSSSKSGHRKRAS 564 Query: 290 LS 291 S Sbjct: 565 KS 566 Score = 28.9 bits (63), Expect = 6.5 Identities = 23/84 (27%), Positives = 38/84 (45%), Gaps = 6/84 (7%) Query: 220 QIREKLDQLRKTVAEKQEKRNQDRLRRREEREREERLSRRSGSRTRDRRRSRSRDRRRR- 278 Q +EK Q+ +T KQEK N+ + + ERE R D R+ S+ +R+ Sbjct: 823 QEKEKQGQMERT-HNKQEK-NRGEEKSKSERECPHSKKRTLKENLSDHLRNGSKPKRKNY 880 Query: 279 ---RSRSTSRERRKLSRSRSRDRH 299 + S S R ++++ D H Sbjct: 881 AGSKWDSESNSERDVTKNSKNDSH 904 >gi|119226260 calcium homeostasis endoplasmic reticulum protein [Homo sapiens] Length = 916 Score = 60.8 bits (146), Expect = 2e-09 Identities = 45/105 (42%), Positives = 53/105 (50%), Gaps = 17/105 (16%) Query: 227 QLRKTVAEKQEKRNQDRLRRREEREREERLSRRSGSRT----------RDRRRSRSRDRR 276 ++R + QEKRN R R + R S RS SR+ R R SRS R Sbjct: 720 KMRARRRKGQEKRNSGPSRSRSRSKSRGRSSSRSNSRSSKSSGSYSRSRSRSCSRSYSRS 779 Query: 277 RRRSRSTSRERRKLSRSRSRDRHRRHRSRSRSHSRGHRRASRDRS 321 R RSRS SR R SRS+S RSRS+S+S G RR SR RS Sbjct: 780 RSRSRSRSRSSRSRSRSQS-------RSRSKSYSPGRRRRSRSRS 817 Score = 52.8 bits (125), Expect = 4e-07 Identities = 41/89 (46%), Positives = 48/89 (53%), Gaps = 4/89 (4%) Query: 239 RNQDRLRRREEREREERLSRRSGSRTRDRRRSRSRDRRR--RRSRSTSRER-RKLSRSRS 295 R + R RRR+ +E+ RS SR++ R RS SR R + S S SR R R SRS S Sbjct: 718 RAKMRARRRKGQEKRNSGPSRSRSRSKSRGRSSSRSNSRSSKSSGSYSRSRSRSCSRSYS 777 Query: 296 RDRHRRHRSRSRSHSRGHRRASRDRSAKY 324 R R R RSRSRS R SR RS Y Sbjct: 778 RSRSRS-RSRSRSSRSRSRSQSRSRSKSY 805 Score = 35.4 bits (80), Expect = 0.070 Identities = 35/95 (36%), Positives = 42/95 (44%), Gaps = 22/95 (23%) Query: 249 EREREERLSRRSGSRTRDRRRSRSRDRR----------RRRSRSTSRER---------RK 289 +R R ++G R + R+R R+ R RSRS SR R K Sbjct: 700 DRPRNSEGWEQNGLYEFFRAKMRARRRKGQEKRNSGPSRSRSRSKSRGRSSSRSNSRSSK 759 Query: 290 LSRSRSRDRHR---RHRSRSRSHSRGHRRASRDRS 321 S S SR R R R SRSRS SR R+SR RS Sbjct: 760 SSGSYSRSRSRSCSRSYSRSRSRSRSRSRSSRSRS 794 >gi|21361282 splicing factor, arginine/serine-rich 4 [Homo sapiens] Length = 494 Score = 60.5 bits (145), Expect = 2e-09 Identities = 50/175 (28%), Positives = 82/175 (46%), Gaps = 6/175 (3%) Query: 154 KILMEVEKVRAKKKEAEEEYRNSMPASSFQQQKLRVCEVCSAYLGLHDNDRRLADHFGGK 213 ++++E R ++ ++ R + + K R E ++ D R L G + Sbjct: 105 RLIVENLSSRCSWQDLKDYMRQAGEVTYADAHKGRKNEGVIEFVSYSDMKRALEKLDGTE 164 Query: 214 LHLGFIQ-IREKLDQLRKTVAEKQEKRNQDRLRRREEREREERL--SRRSGSRTRDRRRS 270 ++ I+ + +K R+ + ++ R R R R+ R S+ S S++R R RS Sbjct: 165 VNGRKIRLVEDKPGSRRRRSYSRSRSHSRSRSRSRHSRKSRSRSGSSKSSHSKSRSRSRS 224 Query: 271 RSRDRRRRRSRSTSRERRKLSRSRSRDRHRRHRSRSRSHSRGHRRASRDRSAKYK 325 SR R + RSRS SR R K +SRS + +SRSRSHS G R+ A+ K Sbjct: 225 GSRSRSKSRSRSQSRSRSKKEKSRSPS---KEKSRSRSHSAGKSRSKSKDQAEEK 276 Score = 59.7 bits (143), Expect = 3e-09 Identities = 35/97 (36%), Positives = 52/97 (53%), Gaps = 5/97 (5%) Query: 227 QLRKTVAEKQEKRNQDRLRRREEREREERLSRRSGSRTRDRRRSRSRDRRRRRSRSTSRE 286 Q R+ EK+ ++ R + + R+ R + GSR+R R RS+S+D+R+ R RS Sbjct: 305 QERRVEEEKRGSVSRGRSQEKSLRQSRSRSRSKGGSRSRSRSRSKSKDKRKGRKRS---- 360 Query: 287 RRKLSRSRSRDRHRRHRSRSRSHSRGHRRASRDRSAK 323 R+ SRSRSR R + RSR R R + S + K Sbjct: 361 -REESRSRSRSRSKSERSRKRGSKRDSKAGSSKKKKK 396 Score = 58.2 bits (139), Expect = 1e-08 Identities = 36/107 (33%), Positives = 55/107 (51%), Gaps = 2/107 (1%) Query: 219 IQIREKLDQLRKTVAEKQEKRNQDRLRRREEREREERLSRRSGSRTRDR--RRSRSRDRR 276 IQ + + + + + + +++ R R +E R EE+ S R++++ R+SRSR R Sbjct: 277 IQNNDNVGKPKSRSPSRHKSKSKSRSRSQERRVEEEKRGSVSRGRSQEKSLRQSRSRSRS 336 Query: 277 RRRSRSTSRERRKLSRSRSRDRHRRHRSRSRSHSRGHRRASRDRSAK 323 + SRS SR R K R + R SRSRS SR SR R +K Sbjct: 337 KGGSRSRSRSRSKSKDKRKGRKRSREESRSRSRSRSKSERSRKRGSK 383 Score = 58.2 bits (139), Expect = 1e-08 Identities = 38/97 (39%), Positives = 54/97 (55%), Gaps = 2/97 (2%) Query: 230 KTVAEKQEKRNQDRLRRREERER-EERLSRRSGSRTRDRRRSRSRDRRRRRSRSTSRERR 288 K+ + QE+R ++ R R R +E+ R+S SR+R + SRSR R R +S+ R+ R Sbjct: 299 KSRSRSQERRVEEEKRGSVSRGRSQEKSLRQSRSRSRSKGGSRSRSRSRSKSKD-KRKGR 357 Query: 289 KLSRSRSRDRHRRHRSRSRSHSRGHRRASRDRSAKYK 325 K SR SR R R RS RG +R S+ S+K K Sbjct: 358 KRSREESRSRSRSRSKSERSRKRGSKRDSKAGSSKKK 394 Score = 52.0 bits (123), Expect = 7e-07 Identities = 61/254 (24%), Positives = 107/254 (42%), Gaps = 30/254 (11%) Query: 100 RTELAKKRLAETQEEISAEVSAKAEKVHELN-EEIGKLLAKAEQLGAEGNVDESQKILME 158 R+ K++ +E S S A K + ++ + + + +G + S+ Sbjct: 239 RSRSKKEKSRSPSKEKSRSRSHSAGKSRSKSKDQAEEKIQNNDNVGKPKSRSPSRHKSKS 298 Query: 159 VEKVRAKKKEAEEEYRNSMPASSFQQQKLRVCEVCSAYLG---------LHDNDRRLADH 209 + R++++ EEE R S+ Q++ LR S G D+R Sbjct: 299 KSRSRSQERRVEEEKRGSVSRGRSQEKSLRQSRSRSRSKGGSRSRSRSRSKSKDKRKGRK 358 Query: 210 FGGKLHLGFIQIREKLDQLRKTVAEKQEKRNQDRLRRREEREREE-RLSRRSGSRTRDRR 268 + + R K ++ RK +++ K + +++E+ +R + R RS S+ R+ Sbjct: 359 RSREESRSRSRSRSKSERSRKRGSKRDSKAGSSKKKKKEDTDRSQSRSPSRSVSKEREHA 418 Query: 269 RSRSRDRR--------------RRRSRSTSRERRKL---SRSRSRDRHRRHRSRSRSHSR 311 +S S R R RSRS S+ + L SRSRS+ + RSRS+S SR Sbjct: 419 KSESSQREGRGESENAGTNQETRSRSRSNSKSKPNLPSESRSRSKSASKT-RSRSKSRSR 477 Query: 312 GHRRA-SRDRSAKY 324 R+ SR RS + Sbjct: 478 SASRSPSRSRSRSH 491 Score = 48.5 bits (114), Expect = 8e-06 Identities = 44/224 (19%), Positives = 91/224 (40%), Gaps = 19/224 (8%) Query: 100 RTELAKKRLAETQEEISAEVSAKAEKVHELNEEIGKLLAKAEQLGAEGNVDESQKILMEV 159 R+ + ++++ + +K EK ++E + + + + D++++ + Sbjct: 221 RSRSGSRSRSKSRSRSQSRSRSKKEKSRSPSKEKSRSRSHSAGKSRSKSKDQAEEKIQNN 280 Query: 160 EKVRAKKKEAEEEYRNSMPASSFQQQKLRVCEVCSAYLGLHDNDRRLADHFGGKLHLGFI 219 + V K + +++ + S Q+ RR+ + G + G Sbjct: 281 DNVGKPKSRSPSRHKSKSKSRSRSQE------------------RRVEEEKRGSVSRGRS 322 Query: 220 QIREKLDQLRKTVAEKQEKRNQDRLRRREEREREERLSRRSGSRTRDRRRSRSRDRRRRR 279 Q + L Q R K R++ R R + + +R+ R R SR+R R RS+S R+R Sbjct: 323 Q-EKSLRQSRSRSRSKGGSRSRSRSRSKSKDKRKGRKRSREESRSRSRSRSKSERSRKRG 381 Query: 280 SRSTSRERRKLSRSRSRDRHRRHRSRSRSHSRGHRRASRDRSAK 323 S+ S+ + + + RS SRS S+ A + S + Sbjct: 382 SKRDSKAGSSKKKKKEDTDRSQSRSPSRSVSKEREHAKSESSQR 425 Score = 35.0 bits (79), Expect = 0.091 Identities = 32/116 (27%), Positives = 49/116 (42%), Gaps = 30/116 (25%) Query: 229 RKTVAEKQEKRNQDRLRRREEREREERLSRRSGSRTR--------DRRRS---RSRDRRR 277 R + ++++ R + + R RSGSR+R R RS +SR + Sbjct: 193 RSRSRSRHSRKSRSRSGSSKSSHSKSRSRSRSGSRSRSKSRSRSQSRSRSKKEKSRSPSK 252 Query: 278 RRSRSTSRERRKLSRSRSRDRHR------------------RHRSRSRSHSRGHRR 315 +SRS S K SRS+S+D+ RH+S+S+S SR R Sbjct: 253 EKSRSRSHSAGK-SRSKSKDQAEEKIQNNDNVGKPKSRSPSRHKSKSKSRSRSQER 307 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.318 0.130 0.358 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 10,707,575 Number of Sequences: 37866 Number of extensions: 472269 Number of successful extensions: 18838 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 492 Number of HSP's successfully gapped in prelim test: 572 Number of HSP's that attempted gapping in prelim test: 5211 Number of HSP's gapped (non-prelim): 5874 length of query: 325 length of database: 18,247,518 effective HSP length: 102 effective length of query: 223 effective length of database: 14,385,186 effective search space: 3207896478 effective search space used: 3207896478 T: 11 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits) S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.