Guide to the Human Genome
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Search of human proteins with 8922297

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|8922297 LUC7-like isoform a [Homo sapiens]
         (325 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|41393554 LUC7-like isoform b [Homo sapiens]                        639   0.0  
gi|8922297 LUC7-like isoform a [Homo sapiens]                         639   0.0  
gi|116812577 LUC7-like 2 [Homo sapiens]                               523   e-148
gi|52426743 cisplatin resistance-associated overexpressed protei...   204   9e-53
gi|19923485 cisplatin resistance-associated overexpressed protei...   204   9e-53
gi|38146113 arginine/serine-rich coiled-coil 2 isoform b [Homo s...    83   4e-16
gi|38146107 arginine/serine-rich coiled-coil 2 isoform a [Homo s...    83   4e-16
gi|41327773 DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 [Homo sapi...    75   6e-14
gi|29568103 U1 small nuclear ribonucleoprotein 70 kDa [Homo sapi...    70   3e-12
gi|42560244 peptidylprolyl isomerase G [Homo sapiens]                  70   3e-12
gi|4826690 DEAH (Asp-Glu-Ala-His) box polypeptide 8 [Homo sapiens]     69   7e-12
gi|239754909 PREDICTED: hypothetical protein [Homo sapiens]            66   5e-11
gi|166235169 PRP38 pre-mRNA processing factor 38 (yeast) domain ...    66   5e-11
gi|55741709 RNA binding motif protein 25 [Homo sapiens]                65   1e-10
gi|239749449 PREDICTED: hypothetical protein [Homo sapiens]            65   1e-10
gi|21040326 SON DNA-binding protein isoform F [Homo sapiens]           65   1e-10
gi|21040314 SON DNA-binding protein isoform B [Homo sapiens]           65   1e-10
gi|239747134 PREDICTED: hypothetical protein XP_002343921 [Homo ...    64   2e-10
gi|116008442 zinc finger CCCH-type containing 13 [Homo sapiens]        64   2e-10
gi|20127499 arginine/serine-rich splicing factor 6 [Homo sapiens]      63   4e-10
gi|41327771 DEAD (Asp-Glu-Ala-Asp) box polypeptide 23 [Homo sapi...    63   4e-10
gi|4759100 splicing factor, arginine/serine-rich 11 [Homo sapiens]     62   5e-10
gi|4827046 U2 small nuclear RNA auxiliary factor 1-like 2 [Homo ...    62   7e-10
gi|24762236 PRP38 pre-mRNA processing factor 38 (yeast) domain c...    62   7e-10
gi|148746195 trichohyalin [Homo sapiens]                               62   9e-10
gi|62460633 RNA-binding motif protein 16 [Homo sapiens]                62   9e-10
gi|7662238 apoptotic chromatin condensation inducer 1 [Homo sapi...    61   1e-09
gi|6631100 natural killer-tumor recognition sequence [Homo sapiens]    61   1e-09
gi|119226260 calcium homeostasis endoplasmic reticulum protein [...    61   2e-09
gi|21361282 splicing factor, arginine/serine-rich 4 [Homo sapiens]     60   2e-09

>gi|41393554 LUC7-like isoform b [Homo sapiens]
          Length = 371

 Score =  639 bits (1647), Expect = 0.0
 Identities = 325/325 (100%), Positives = 325/325 (100%)

Query: 1   MSAQAQMRALLDQLMGTARDGDETRQRVKFTDDRVCKSHLLDCCPHDILAGTRMDLGECT 60
           MSAQAQMRALLDQLMGTARDGDETRQRVKFTDDRVCKSHLLDCCPHDILAGTRMDLGECT
Sbjct: 1   MSAQAQMRALLDQLMGTARDGDETRQRVKFTDDRVCKSHLLDCCPHDILAGTRMDLGECT 60

Query: 61  KIHDLALRADYEIASKERDLFFELDAMDHLESFIAECDRRTELAKKRLAETQEEISAEVS 120
           KIHDLALRADYEIASKERDLFFELDAMDHLESFIAECDRRTELAKKRLAETQEEISAEVS
Sbjct: 61  KIHDLALRADYEIASKERDLFFELDAMDHLESFIAECDRRTELAKKRLAETQEEISAEVS 120

Query: 121 AKAEKVHELNEEIGKLLAKAEQLGAEGNVDESQKILMEVEKVRAKKKEAEEEYRNSMPAS 180
           AKAEKVHELNEEIGKLLAKAEQLGAEGNVDESQKILMEVEKVRAKKKEAEEEYRNSMPAS
Sbjct: 121 AKAEKVHELNEEIGKLLAKAEQLGAEGNVDESQKILMEVEKVRAKKKEAEEEYRNSMPAS 180

Query: 181 SFQQQKLRVCEVCSAYLGLHDNDRRLADHFGGKLHLGFIQIREKLDQLRKTVAEKQEKRN 240
           SFQQQKLRVCEVCSAYLGLHDNDRRLADHFGGKLHLGFIQIREKLDQLRKTVAEKQEKRN
Sbjct: 181 SFQQQKLRVCEVCSAYLGLHDNDRRLADHFGGKLHLGFIQIREKLDQLRKTVAEKQEKRN 240

Query: 241 QDRLRRREEREREERLSRRSGSRTRDRRRSRSRDRRRRRSRSTSRERRKLSRSRSRDRHR 300
           QDRLRRREEREREERLSRRSGSRTRDRRRSRSRDRRRRRSRSTSRERRKLSRSRSRDRHR
Sbjct: 241 QDRLRRREEREREERLSRRSGSRTRDRRRSRSRDRRRRRSRSTSRERRKLSRSRSRDRHR 300

Query: 301 RHRSRSRSHSRGHRRASRDRSAKYK 325
           RHRSRSRSHSRGHRRASRDRSAKYK
Sbjct: 301 RHRSRSRSHSRGHRRASRDRSAKYK 325


>gi|8922297 LUC7-like isoform a [Homo sapiens]
          Length = 325

 Score =  639 bits (1647), Expect = 0.0
 Identities = 325/325 (100%), Positives = 325/325 (100%)

Query: 1   MSAQAQMRALLDQLMGTARDGDETRQRVKFTDDRVCKSHLLDCCPHDILAGTRMDLGECT 60
           MSAQAQMRALLDQLMGTARDGDETRQRVKFTDDRVCKSHLLDCCPHDILAGTRMDLGECT
Sbjct: 1   MSAQAQMRALLDQLMGTARDGDETRQRVKFTDDRVCKSHLLDCCPHDILAGTRMDLGECT 60

Query: 61  KIHDLALRADYEIASKERDLFFELDAMDHLESFIAECDRRTELAKKRLAETQEEISAEVS 120
           KIHDLALRADYEIASKERDLFFELDAMDHLESFIAECDRRTELAKKRLAETQEEISAEVS
Sbjct: 61  KIHDLALRADYEIASKERDLFFELDAMDHLESFIAECDRRTELAKKRLAETQEEISAEVS 120

Query: 121 AKAEKVHELNEEIGKLLAKAEQLGAEGNVDESQKILMEVEKVRAKKKEAEEEYRNSMPAS 180
           AKAEKVHELNEEIGKLLAKAEQLGAEGNVDESQKILMEVEKVRAKKKEAEEEYRNSMPAS
Sbjct: 121 AKAEKVHELNEEIGKLLAKAEQLGAEGNVDESQKILMEVEKVRAKKKEAEEEYRNSMPAS 180

Query: 181 SFQQQKLRVCEVCSAYLGLHDNDRRLADHFGGKLHLGFIQIREKLDQLRKTVAEKQEKRN 240
           SFQQQKLRVCEVCSAYLGLHDNDRRLADHFGGKLHLGFIQIREKLDQLRKTVAEKQEKRN
Sbjct: 181 SFQQQKLRVCEVCSAYLGLHDNDRRLADHFGGKLHLGFIQIREKLDQLRKTVAEKQEKRN 240

Query: 241 QDRLRRREEREREERLSRRSGSRTRDRRRSRSRDRRRRRSRSTSRERRKLSRSRSRDRHR 300
           QDRLRRREEREREERLSRRSGSRTRDRRRSRSRDRRRRRSRSTSRERRKLSRSRSRDRHR
Sbjct: 241 QDRLRRREEREREERLSRRSGSRTRDRRRSRSRDRRRRRSRSTSRERRKLSRSRSRDRHR 300

Query: 301 RHRSRSRSHSRGHRRASRDRSAKYK 325
           RHRSRSRSHSRGHRRASRDRSAKYK
Sbjct: 301 RHRSRSRSHSRGHRRASRDRSAKYK 325


>gi|116812577 LUC7-like 2 [Homo sapiens]
          Length = 392

 Score =  523 bits (1346), Expect = e-148
 Identities = 262/327 (80%), Positives = 300/327 (91%), Gaps = 6/327 (1%)

Query: 1   MSAQAQMRALLDQLMGTARDGDETRQRVKFTDDRVCKSHLLDCCPHDILAGTRMDLGECT 60
           MSAQAQMRA+LDQLMGT+RDGD TRQR+KF+DDRVCKSHLL+CCPHD+L+GTRMDLGEC 
Sbjct: 1   MSAQAQMRAMLDQLMGTSRDGDTTRQRIKFSDDRVCKSHLLNCCPHDVLSGTRMDLGECL 60

Query: 61  KIHDLALRADYEIASKERDLFFELDAMDHLESFIAECDRRTELAKKRLAETQEEISAEVS 120
           K+HDLALRADYEIASKE+D FFELDAMDHL+SFIA+CDRRTE+AKKRLAETQEEISAEV+
Sbjct: 61  KVHDLALRADYEIASKEQDFFFELDAMDHLQSFIADCDRRTEVAKKRLAETQEEISAEVA 120

Query: 121 AKAEKVHELNEEIGKLLAKAEQLGAEGNVDESQKILMEVEKVRAKKKEAEEEYRNSMPAS 180
           AKAE+VHELNEEIGKLLAK EQLGAEGNV+ESQK++ EVEK RAKK+EAEE YRNSMPAS
Sbjct: 121 AKAERVHELNEEIGKLLAKVEQLGAEGNVEESQKVMDEVEKARAKKREAEEVYRNSMPAS 180

Query: 181 SFQQQKLRVCEVCSAYLGLHDNDRRLADHFGGKLHLGFIQIREKLDQLRKTVAEKQEKRN 240
           SFQQQKLRVCEVCSAYLGLHDNDRRLADHFGGKLHLGFI+IREKL++L++ VAEKQEKRN
Sbjct: 181 SFQQQKLRVCEVCSAYLGLHDNDRRLADHFGGKLHLGFIEIREKLEELKRVVAEKQEKRN 240

Query: 241 QDRLRRREEREREERLS-RRSGSRTRDRRRSRSRDRRRRRSRSTSRERRKLSRSRSRDRH 299
           Q+RL+RREEREREER   RRS S +++ +RSRSR+ RR RSRS SRER++ +RS+SR++ 
Sbjct: 241 QERLKRREEREREEREKLRRSRSHSKNPKRSRSREHRRHRSRSMSRERKRRTRSKSREKR 300

Query: 300 RRHRSR--SRSHSRGHRR---ASRDRS 321
            RHRSR  SRS SR H+R   +SRDRS
Sbjct: 301 HRHRSRSSSRSRSRSHQRSRHSSRDRS 327


>gi|52426743 cisplatin resistance-associated overexpressed protein
           [Homo sapiens]
          Length = 432

 Score =  204 bits (519), Expect = 9e-53
 Identities = 118/326 (36%), Positives = 191/326 (58%), Gaps = 13/326 (3%)

Query: 10  LLDQLMGTARD--GDETRQRVKFTDDRVCKSHLLDCCPHDILAGTRMDLGECTKIHDLAL 67
           LLD+LMG  R+   DE R  V++  + VCK +L   CP ++   TR DLG C KIHD  L
Sbjct: 7   LLDELMGRDRNLAPDEKRSNVRWDHESVCKYYLCGFCPAELFTNTRSDLGPCEKIHDENL 66

Query: 68  RADYEIASKERDLFFELDAMDHLESFIAECDRRTELAKKRLAETQEEISAEVSAKA---- 123
           R  YE +S+   + +E D + +L+S +AE +RR      RLA +Q + S+  +       
Sbjct: 67  RKQYEKSSRFMKVGYERDFLRYLQSLLAEVERRIRRGHARLALSQNQQSSGAAGPTGKNE 126

Query: 124 EKVHELNEEIGKLLAKAEQLGAEGNVDESQKILMEVEKVRAKKKEAEEEYRNSMPASSFQ 183
           EK+  L ++I  LL + E+LG+EG V+E+Q ++  VE+++ +++E      +++ + + Q
Sbjct: 127 EKIQVLTDKIDVLLQQIEELGSEGKVEEAQGMMKLVEQLK-EERELLRSTTSTIESFAAQ 185

Query: 184 QQKLRVCEVCSAYLGLHDNDRRLADHFGGKLHLGFIQIREKLDQLRKTVAEKQEKRNQDR 243
           ++++ VCEVC A+L + D   R+ DH  GK H+G+ +I+  +++L++ + ++ E+ ++D 
Sbjct: 186 EKQMEVCEVCGAFLIVGDAQSRVDDHLMGKQHMGYAKIKATVEELKEKLRKRTEEPDRDE 245

Query: 244 LRRREEREREERLSRRSGSRTRDRRRSRSRDRRRRRSRSTSRERRKLSRSRSRDRHR--- 300
             ++E++EREER   R   R    R+ R  +  R + R+  RERRK SRSRSR   R   
Sbjct: 246 RLKKEKQEREEREKEREREREERERKRRREEEEREKERARDRERRKRSRSRSRHSSRTSD 305

Query: 301 RHRSRSRSHSRG---HRRASRDRSAK 323
           R  SRSR H R     RR SR R  +
Sbjct: 306 RRCSRSRDHKRSRSRERRRSRSRDRR 331



 Score = 62.0 bits (149), Expect = 7e-10
 Identities = 53/209 (25%), Positives = 95/209 (45%), Gaps = 21/209 (10%)

Query: 117 AEVSAKAEKVHELNEEIGKLLAKAEQLGAEGNVDESQKILMEVEKVRAKKKEAEEEYRNS 176
           A++ A  E++ E      KL  + E+   +  + + ++   E EK R +++E E E +  
Sbjct: 221 AKIKATVEELKE------KLRKRTEEPDRDERLKKEKQEREEREKERERERE-ERERKRR 273

Query: 177 MPASSFQQQKLRVCEVCSAYLGLHDNDRRLADHFGGKLHLGFIQIREKLDQLRKTVAEKQ 236
                 ++++ R  E          +  R +D           +     D  R    E++
Sbjct: 274 REEEEREKERARDRERRKRSRSRSRHSSRTSDR----------RCSRSRDHKRSRSRERR 323

Query: 237 EKRNQDRLRRREEREREERLSRRSGSRTRDRRRSRSRDRRRRRSRSTSRERRKLSRSRSR 296
             R++DR RR    +R ER  R   SR+RDRRRS+SRDR+  + RS SR+R +  +S+ +
Sbjct: 324 RSRSRDR-RRSRSHDRSERKHR---SRSRDRRRSKSRDRKSYKHRSKSRDREQDRKSKEK 379

Query: 297 DRHRRHRSRSRSHSRGHRRASRDRSAKYK 325
           ++      +S   S    + S D + + K
Sbjct: 380 EKRGSDDKKSSVKSGSREKQSEDTNTESK 408


>gi|19923485 cisplatin resistance-associated overexpressed protein
           [Homo sapiens]
          Length = 432

 Score =  204 bits (519), Expect = 9e-53
 Identities = 118/326 (36%), Positives = 191/326 (58%), Gaps = 13/326 (3%)

Query: 10  LLDQLMGTARD--GDETRQRVKFTDDRVCKSHLLDCCPHDILAGTRMDLGECTKIHDLAL 67
           LLD+LMG  R+   DE R  V++  + VCK +L   CP ++   TR DLG C KIHD  L
Sbjct: 7   LLDELMGRDRNLAPDEKRSNVRWDHESVCKYYLCGFCPAELFTNTRSDLGPCEKIHDENL 66

Query: 68  RADYEIASKERDLFFELDAMDHLESFIAECDRRTELAKKRLAETQEEISAEVSAKA---- 123
           R  YE +S+   + +E D + +L+S +AE +RR      RLA +Q + S+  +       
Sbjct: 67  RKQYEKSSRFMKVGYERDFLRYLQSLLAEVERRIRRGHARLALSQNQQSSGAAGPTGKNE 126

Query: 124 EKVHELNEEIGKLLAKAEQLGAEGNVDESQKILMEVEKVRAKKKEAEEEYRNSMPASSFQ 183
           EK+  L ++I  LL + E+LG+EG V+E+Q ++  VE+++ +++E      +++ + + Q
Sbjct: 127 EKIQVLTDKIDVLLQQIEELGSEGKVEEAQGMMKLVEQLK-EERELLRSTTSTIESFAAQ 185

Query: 184 QQKLRVCEVCSAYLGLHDNDRRLADHFGGKLHLGFIQIREKLDQLRKTVAEKQEKRNQDR 243
           ++++ VCEVC A+L + D   R+ DH  GK H+G+ +I+  +++L++ + ++ E+ ++D 
Sbjct: 186 EKQMEVCEVCGAFLIVGDAQSRVDDHLMGKQHMGYAKIKATVEELKEKLRKRTEEPDRDE 245

Query: 244 LRRREEREREERLSRRSGSRTRDRRRSRSRDRRRRRSRSTSRERRKLSRSRSRDRHR--- 300
             ++E++EREER   R   R    R+ R  +  R + R+  RERRK SRSRSR   R   
Sbjct: 246 RLKKEKQEREEREKEREREREERERKRRREEEEREKERARDRERRKRSRSRSRHSSRTSD 305

Query: 301 RHRSRSRSHSRG---HRRASRDRSAK 323
           R  SRSR H R     RR SR R  +
Sbjct: 306 RRCSRSRDHKRSRSRERRRSRSRDRR 331



 Score = 62.0 bits (149), Expect = 7e-10
 Identities = 53/209 (25%), Positives = 95/209 (45%), Gaps = 21/209 (10%)

Query: 117 AEVSAKAEKVHELNEEIGKLLAKAEQLGAEGNVDESQKILMEVEKVRAKKKEAEEEYRNS 176
           A++ A  E++ E      KL  + E+   +  + + ++   E EK R +++E E E +  
Sbjct: 221 AKIKATVEELKE------KLRKRTEEPDRDERLKKEKQEREEREKERERERE-ERERKRR 273

Query: 177 MPASSFQQQKLRVCEVCSAYLGLHDNDRRLADHFGGKLHLGFIQIREKLDQLRKTVAEKQ 236
                 ++++ R  E          +  R +D           +     D  R    E++
Sbjct: 274 REEEEREKERARDRERRKRSRSRSRHSSRTSDR----------RCSRSRDHKRSRSRERR 323

Query: 237 EKRNQDRLRRREEREREERLSRRSGSRTRDRRRSRSRDRRRRRSRSTSRERRKLSRSRSR 296
             R++DR RR    +R ER  R   SR+RDRRRS+SRDR+  + RS SR+R +  +S+ +
Sbjct: 324 RSRSRDR-RRSRSHDRSERKHR---SRSRDRRRSKSRDRKSYKHRSKSRDREQDRKSKEK 379

Query: 297 DRHRRHRSRSRSHSRGHRRASRDRSAKYK 325
           ++      +S   S    + S D + + K
Sbjct: 380 EKRGSDDKKSSVKSGSREKQSEDTNTESK 408


>gi|38146113 arginine/serine-rich coiled-coil 2 isoform b [Homo
           sapiens]
          Length = 375

 Score = 82.8 bits (203), Expect = 4e-16
 Identities = 50/100 (50%), Positives = 64/100 (64%), Gaps = 4/100 (4%)

Query: 222 REKLDQLRKTVAEKQEKRNQDRLRRREEREREERLSRRSGSRTRDRRRSRSRDRRRRRSR 281
           RE+L+       E + KR + +  R     R     RR  SR+R+R++SRSR R R++SR
Sbjct: 40  RERLNSSEN--GEDRHKRKERKSSRGRSHSRSRSRERRHRSRSRERKKSRSRSRERKKSR 97

Query: 282 STSRERRKLSRSRSRDRHRRHRSRSRSHSRGHRRASRDRS 321
           S SRER+K SRSRSR+R RR RSRSRS SR HR  +R RS
Sbjct: 98  SRSRERKK-SRSRSRERKRRIRSRSRSRSR-HRHRTRSRS 135



 Score = 80.9 bits (198), Expect = 1e-15
 Identities = 46/96 (47%), Positives = 62/96 (64%), Gaps = 4/96 (4%)

Query: 229 RKTVAEKQEKRNQDRLRRREEREREERLSRRSGSRTRDRRRSRSRDRRRRRSRSTSRERR 288
           RK+   +   R++ R RR   R RE + SR   SR+R+R++SRSR R R++SRS SRER+
Sbjct: 58  RKSSRGRSHSRSRSRERRHRSRSRERKKSR---SRSRERKKSRSRSRERKKSRSRSRERK 114

Query: 289 KLSRSRSRDRHR-RHRSRSRSHSRGHRRASRDRSAK 323
           +  RSRSR R R RHR+RSRS +R   R  + R  K
Sbjct: 115 RRIRSRSRSRSRHRHRTRSRSRTRSRSRDRKKRIEK 150



 Score = 62.0 bits (149), Expect = 7e-10
 Identities = 41/93 (44%), Positives = 51/93 (54%), Gaps = 9/93 (9%)

Query: 234 EKQEKRNQDRLRRREEREREERLSRRSGSRTRDRRRSRSRDRRRRRSRSTSRERRKLSRS 293
           E    + ++RL   E  E   +   R  SR R   RSRSR+RR R   S SRER+K SRS
Sbjct: 33  EHSSDKGRERLNSSENGEDRHKRKERKSSRGRSHSRSRSRERRHR---SRSRERKK-SRS 88

Query: 294 RSRDRHR-----RHRSRSRSHSRGHRRASRDRS 321
           RSR+R +     R R +SRS SR  +R  R RS
Sbjct: 89  RSRERKKSRSRSRERKKSRSRSRERKRRIRSRS 121



 Score = 58.9 bits (141), Expect = 6e-09
 Identities = 38/99 (38%), Positives = 50/99 (50%), Gaps = 4/99 (4%)

Query: 230 KTVAEKQEKRNQDRLRRREEREREERLSRRSGSRTRDRRRSRSRDRRRRRSRSTSRERRK 289
           K  + K+ K  +   +     +  ERL+       R +R+ R   R R  SRS SRERR 
Sbjct: 17  KDKSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSSRGRSHSRSRSRERRH 76

Query: 290 LSRSRSRDRHR---RHRSRSRSHSRGHRRASRDRSAKYK 325
            SRSR R + R   R R +SRS SR  R+ SR RS + K
Sbjct: 77  RSRSRERKKSRSRSRERKKSRSRSR-ERKKSRSRSRERK 114



 Score = 55.8 bits (133), Expect = 5e-08
 Identities = 47/155 (30%), Positives = 73/155 (47%), Gaps = 13/155 (8%)

Query: 161 KVRAKKKEAEEEYRNSMPASSFQQQKLRVCEVCSAYLGLHDNDRRLADHFGGKLHLGFIQ 220
           K ++ KK   EE+ +   +S   +++L      S+  G   + R+      G+ H    +
Sbjct: 17  KDKSSKKHKSEEHNDKEHSSDKGRERLN-----SSENGEDRHKRKERKSSRGRSHS---R 68

Query: 221 IREKLDQLRKTVAEKQEKRNQDRLRRREEREREERLSRRSGSRTRDRR-----RSRSRDR 275
            R +  + R    E+++ R++ R R++      ER   RS SR R RR     RSRSR R
Sbjct: 69  SRSRERRHRSRSRERKKSRSRSRERKKSRSRSRERKKSRSRSRERKRRIRSRSRSRSRHR 128

Query: 276 RRRRSRSTSRERRKLSRSRSRDRHRRHRSRSRSHS 310
            R RSRS +R R +  + R     R  RS SR+ S
Sbjct: 129 HRTRSRSRTRSRSRDRKKRIEKPRRFSRSLSRTPS 163



 Score = 52.8 bits (125), Expect = 4e-07
 Identities = 36/99 (36%), Positives = 53/99 (53%), Gaps = 11/99 (11%)

Query: 235 KQEKRNQDRLRRREEREREERLSRR-SGSRTRDRRRS--RSRDRRRRRSRSTSRERRKLS 291
           KQ +R++ + +  ++ + EE   +  S  + R+R  S     DR +R+ R +SR R   S
Sbjct: 9   KQGRRHESKDKSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSSRGR---S 65

Query: 292 RSRSRDRHRRHRSRSRSHSRG-----HRRASRDRSAKYK 325
            SRSR R RRHRSRSR   +       R+ SR RS + K
Sbjct: 66  HSRSRSRERRHRSRSRERKKSRSRSRERKKSRSRSRERK 104


>gi|38146107 arginine/serine-rich coiled-coil 2 isoform a [Homo
           sapiens]
          Length = 434

 Score = 82.8 bits (203), Expect = 4e-16
 Identities = 50/100 (50%), Positives = 64/100 (64%), Gaps = 4/100 (4%)

Query: 222 REKLDQLRKTVAEKQEKRNQDRLRRREEREREERLSRRSGSRTRDRRRSRSRDRRRRRSR 281
           RE+L+       E + KR + +  R     R     RR  SR+R+R++SRSR R R++SR
Sbjct: 99  RERLNSSEN--GEDRHKRKERKSSRGRSHSRSRSRERRHRSRSRERKKSRSRSRERKKSR 156

Query: 282 STSRERRKLSRSRSRDRHRRHRSRSRSHSRGHRRASRDRS 321
           S SRER+K SRSRSR+R RR RSRSRS SR HR  +R RS
Sbjct: 157 SRSRERKK-SRSRSRERKRRIRSRSRSRSR-HRHRTRSRS 194



 Score = 80.9 bits (198), Expect = 1e-15
 Identities = 46/96 (47%), Positives = 62/96 (64%), Gaps = 4/96 (4%)

Query: 229 RKTVAEKQEKRNQDRLRRREEREREERLSRRSGSRTRDRRRSRSRDRRRRRSRSTSRERR 288
           RK+   +   R++ R RR   R RE + SR   SR+R+R++SRSR R R++SRS SRER+
Sbjct: 117 RKSSRGRSHSRSRSRERRHRSRSRERKKSR---SRSRERKKSRSRSRERKKSRSRSRERK 173

Query: 289 KLSRSRSRDRHR-RHRSRSRSHSRGHRRASRDRSAK 323
           +  RSRSR R R RHR+RSRS +R   R  + R  K
Sbjct: 174 RRIRSRSRSRSRHRHRTRSRSRTRSRSRDRKKRIEK 209



 Score = 62.0 bits (149), Expect = 7e-10
 Identities = 60/220 (27%), Positives = 97/220 (44%), Gaps = 31/220 (14%)

Query: 112 QEEISAEVSAKAEKVHELNEEIGKLLAKAEQLGAEGNVDESQKILME----VEKVRAKKK 167
           +E+    VS +A K H  +    +   +  +   EG    S+    E      K ++ KK
Sbjct: 24  KEQSEVSVSPRASK-HHYSRSRSRSRERKRKSDNEGRKHRSRSRSKEGRRHESKDKSSKK 82

Query: 168 EAEEEYRNSMPASSFQQQKLRVCEVCSAYLGLHDNDRRLADHFGGKLHLGFIQIREKLDQ 227
              EE+ +   +S   +++L      S+  G   + R+      G+ H            
Sbjct: 83  HKSEEHNDKEHSSDKGRERLN-----SSENGEDRHKRKERKSSRGRSH------------ 125

Query: 228 LRKTVAEKQEKRNQDRLRRREEREREERLSRRSGSRTRDRRRSRSRDRRRRR-----SRS 282
              + +  +E+R++ R R R++     R  ++S SR+R+R++SRSR R R+R     SRS
Sbjct: 126 ---SRSRSRERRHRSRSRERKKSRSRSRERKKSRSRSRERKKSRSRSRERKRRIRSRSRS 182

Query: 283 TSRER-RKLSRSRSRDRHRRHRSRSRSHSRGHRRASRDRS 321
            SR R R  SRSR+R R R  + R     R  R  SR  S
Sbjct: 183 RSRHRHRTRSRSRTRSRSRDRKKRIEKPRRFSRSLSRTPS 222



 Score = 60.5 bits (145), Expect = 2e-09
 Identities = 44/125 (35%), Positives = 61/125 (48%), Gaps = 5/125 (4%)

Query: 204 RRLADHFGGKLHLGFIQIREKLDQLRKTVAEKQEKRNQDRLRRREEREREERLSRRSGSR 263
           +R +D+ G K H    + +E      K  + K+ K  +   +     +  ERL+      
Sbjct: 51  KRKSDNEGRK-HRSRSRSKEGRRHESKDKSSKKHKSEEHNDKEHSSDKGRERLNSSENGE 109

Query: 264 TRDRRRSRSRDRRRRRSRSTSRERRKLSRSRSRDRHR---RHRSRSRSHSRGHRRASRDR 320
            R +R+ R   R R  SRS SRERR  SRSR R + R   R R +SRS SR  R+ SR R
Sbjct: 110 DRHKRKERKSSRGRSHSRSRSRERRHRSRSRERKKSRSRSRERKKSRSRSR-ERKKSRSR 168

Query: 321 SAKYK 325
           S + K
Sbjct: 169 SRERK 173



 Score = 51.2 bits (121), Expect = 1e-06
 Identities = 35/116 (30%), Positives = 56/116 (48%), Gaps = 17/116 (14%)

Query: 223 EKLDQLRKTVAEKQEK----RNQDRLRRREEREREERLSRRSGSRTRDRRRSRSRDRRRR 278
           +K +Q   +V+ +  K    R++ R R R+ +   E    RS SR+++ RR  S+D+  +
Sbjct: 22  KKKEQSEVSVSPRASKHHYSRSRSRSRERKRKSDNEGRKHRSRSRSKEGRRHESKDKSSK 81

Query: 279 RSRSTSRERRKLSRSRSR----------DRHRRHR---SRSRSHSRGHRRASRDRS 321
           + +S     ++ S  + R          DRH+R     SR RSHSR   R  R RS
Sbjct: 82  KHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSSRGRSHSRSRSRERRHRS 137



 Score = 44.7 bits (104), Expect = 1e-04
 Identities = 31/98 (31%), Positives = 51/98 (52%), Gaps = 13/98 (13%)

Query: 237 EKRNQDRLRRREEREREERLSRRSGSRTRDRRRSRSRDRRRR--------RSRSTSRE-R 287
           EK + DR +++E+ E    +S R+      R RSRSR+R+R+        RSRS S+E R
Sbjct: 14  EKTSPDRDKKKEQSEVS--VSPRASKHHYSRSRSRSRERKRKSDNEGRKHRSRSRSKEGR 71

Query: 288 RKLSRSRSRDRHR--RHRSRSRSHSRGHRRASRDRSAK 323
           R  S+ +S  +H+   H  +  S  +G  R +   + +
Sbjct: 72  RHESKDKSSKKHKSEEHNDKEHSSDKGRERLNSSENGE 109



 Score = 28.5 bits (62), Expect = 8.5
 Identities = 19/63 (30%), Positives = 26/63 (41%), Gaps = 7/63 (11%)

Query: 266 DRRRSRSRDRRRRRSRSTSRERRKLSRSRSRDRHRRHRSRSRSHSR-------GHRRASR 318
           D  R      +    R   +E+ ++S S    +H   RSRSRS  R       G +  SR
Sbjct: 5   DTERDGLAPEKTSPDRDKKKEQSEVSVSPRASKHHYSRSRSRSRERKRKSDNEGRKHRSR 64

Query: 319 DRS 321
            RS
Sbjct: 65  SRS 67


>gi|41327773 DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 [Homo
           sapiens]
          Length = 1031

 Score = 75.5 bits (184), Expect = 6e-14
 Identities = 45/97 (46%), Positives = 55/97 (56%), Gaps = 3/97 (3%)

Query: 229 RKTVAEKQEKRNQDRLRRREEREREERLSRRSGSRTRDRRRSRSRDRRRRRSRSTSRERR 288
           RK  A +    ++ R R   ++  +    RRS SR RDRRR RSR R +RRSRS  R+R 
Sbjct: 9   RKRSASRGRSGSRSRSRSPSDKRSKRGDDRRSRSRDRDRRRERSRSRDKRRSRSRDRKRL 68

Query: 289 KLSRSRSRDR---HRRHRSRSRSHSRGHRRASRDRSA 322
           + SRSR RDR    RR RSR R  SR   R  R RS+
Sbjct: 69  RRSRSRERDRSRERRRSRSRDRRRSRSRSRGRRSRSS 105



 Score = 74.3 bits (181), Expect = 1e-13
 Identities = 48/96 (50%), Positives = 62/96 (64%), Gaps = 10/96 (10%)

Query: 230 KTVAEKQEKRNQDRLRRREEREREERLSRRSGSRTRDRRRSRSRDRRR-RRSRSTSRER- 287
           ++ ++K+ KR  DR  R  +R+R     RR  SR+RD+RRSRSRDR+R RRSRS  R+R 
Sbjct: 25  RSPSDKRSKRGDDRRSRSRDRDR-----RRERSRSRDKRRSRSRDRKRLRRSRSRERDRS 79

Query: 288 RKLSRSRSRDRHRRHRSRSRSHSRGHRRASRDRSAK 323
           R+  RSRSRD   R RSRSRS  R  R +S    +K
Sbjct: 80  RERRRSRSRD---RRRSRSRSRGRRSRSSSPGNKSK 112



 Score = 67.0 bits (162), Expect = 2e-11
 Identities = 47/89 (52%), Positives = 54/89 (60%), Gaps = 16/89 (17%)

Query: 247 REEREREERLSRR--SGSRTRDR------------RRSRSRDRRRRRSRSTSRERRKLSR 292
           RE R   +R + R  SGSR+R R            RRSRSRDR RRR RS SR++R+ SR
Sbjct: 3   RESRHYRKRSASRGRSGSRSRSRSPSDKRSKRGDDRRSRSRDRDRRRERSRSRDKRR-SR 61

Query: 293 SRSRDRHRRHRSRSRSHSRGHRRA-SRDR 320
           SR R R RR RSR R  SR  RR+ SRDR
Sbjct: 62  SRDRKRLRRSRSRERDRSRERRRSRSRDR 90



 Score = 58.2 bits (139), Expect = 1e-08
 Identities = 35/96 (36%), Positives = 48/96 (50%), Gaps = 1/96 (1%)

Query: 229 RKTVAEKQEKRNQDRLRRREEREREERLSR-RSGSRTRDRRRSRSRDRRRRRSRSTSRER 287
           R    +K+  R++DR R R  R RE   SR R  SR+RDRRRSRSR R RR   S+   +
Sbjct: 51  RSRSRDKRRSRSRDRKRLRRSRSRERDRSRERRRSRSRDRRRSRSRSRGRRSRSSSPGNK 110

Query: 288 RKLSRSRSRDRHRRHRSRSRSHSRGHRRASRDRSAK 323
            K + +RSR + +     S    +  +    D   K
Sbjct: 111 SKKTENRSRSKEKTDGGESSKEKKKDKDDKEDEKEK 146



 Score = 53.1 bits (126), Expect = 3e-07
 Identities = 41/107 (38%), Positives = 57/107 (53%), Gaps = 12/107 (11%)

Query: 229 RKTVAEKQEKRNQDRLRRREE-REREERLSRRSG------SRTRDRRRS----RSRDRRR 277
           R    + +  R++DR RRRE  R R++R SR         SR+R+R RS    RSR R R
Sbjct: 31  RSKRGDDRRSRSRDRDRRRERSRSRDKRRSRSRDRKRLRRSRSRERDRSRERRRSRSRDR 90

Query: 278 RRSRSTSRERRKLSRS-RSRDRHRRHRSRSRSHSRGHRRASRDRSAK 323
           RRSRS SR RR  S S  ++ +   +RSRS+  + G   +   +  K
Sbjct: 91  RRSRSRSRGRRSRSSSPGNKSKKTENRSRSKEKTDGGESSKEKKKDK 137



 Score = 32.0 bits (71), Expect = 0.77
 Identities = 21/108 (19%), Positives = 46/108 (42%), Gaps = 8/108 (7%)

Query: 226 DQLRKTVAEKQEKRNQDRLRRREEREREERLSRRSGSRTRD--------RRRSRSRDRRR 277
           D+ R   +  +E+      RR   R+R    SR  G R+R         +  +RSR + +
Sbjct: 64  DRKRLRRSRSRERDRSRERRRSRSRDRRRSRSRSRGRRSRSSSPGNKSKKTENRSRSKEK 123

Query: 278 RRSRSTSRERRKLSRSRSRDRHRRHRSRSRSHSRGHRRASRDRSAKYK 325
                +S+E++K    +  ++ +   +  ++      R  ++R  K++
Sbjct: 124 TDGGESSKEKKKDKDDKEDEKEKDAGNFDQNKLEEEMRKRKERVEKWR 171


>gi|29568103 U1 small nuclear ribonucleoprotein 70 kDa [Homo
           sapiens]
          Length = 437

 Score = 69.7 bits (169), Expect = 3e-12
 Identities = 43/85 (50%), Positives = 52/85 (61%), Gaps = 9/85 (10%)

Query: 239 RNQDRLRRREEREREERLSRRSGSRTRDRRRSRSRDRRRRRSRSTSRERRKLSRSRSRDR 298
           R++DR R RE RER      R   + R+RRRSRSRD RRRRSRS  +E R+ SR RS+D 
Sbjct: 231 RDRDRDRERERRERS-----RERDKERERRRSRSRD-RRRRSRSRDKEERRRSRERSKD- 283

Query: 299 HRRHRSRSRSHSRGHRRASRDRSAK 323
             + R R R  SR   RA R+R  K
Sbjct: 284 --KDRDRKRRSSRSRERARRERERK 306



 Score = 61.6 bits (148), Expect = 9e-10
 Identities = 37/84 (44%), Positives = 47/84 (55%), Gaps = 4/84 (4%)

Query: 241 QDRLRRREEREREERLSRRSGSRTRDRRR---SRSRDRRRRRSRSTSRERRKLSRSRSRD 297
           +D   R +ER     L  R   R R+R R   SR RD+ R R RS SR+RR+ SRSR ++
Sbjct: 213 RDDTSRYDERPGPSPLPHRDRDRDRERERRERSRERDKERERRRSRSRDRRRRSRSRDKE 272

Query: 298 RHRRHRSRSRSHSRGH-RRASRDR 320
             RR R RS+   R   RR+SR R
Sbjct: 273 ERRRSRERSKDKDRDRKRRSSRSR 296



 Score = 57.4 bits (137), Expect = 2e-08
 Identities = 42/145 (28%), Positives = 60/145 (41%), Gaps = 45/145 (31%)

Query: 222 REKLDQLRKTVAEKQEKRNQDRLRRREEREREERLSRRSGSRTRDRRRSRSRDRRRRRSR 281
           RE+ ++ R+   E++ +R++ R RRR  R R++   RRS    R+R + + RDR+RR SR
Sbjct: 239 RERRERSRERDKERERRRSRSRDRRRRSRSRDKEERRRS----RERSKDKDRDRKRRSSR 294

Query: 282 STSRERRKLSR-----------------------------------------SRSRDRHR 300
           S  R RR+  R                                          R RDR R
Sbjct: 295 SRERARRERERKEELRGGGGDMAEPSEAGDAPPDDGPPGELGPDGPDGPEEKGRDRDRER 354

Query: 301 RHRSRSRSHSRGHRRASRDRSAKYK 325
           R   RS    R  R   RDR  ++K
Sbjct: 355 RRSHRSERERRRDRDRDRDRDREHK 379



 Score = 55.5 bits (132), Expect = 6e-08
 Identities = 37/84 (44%), Positives = 42/84 (50%), Gaps = 7/84 (8%)

Query: 246 RREEREREERLSRRSGSRT---RDRRRSRSRDRRRR-RSRSTSRERRKLSRSRSRDRHRR 301
           R   R+   R   R G      RDR R R R+RR R R R   RERR   RSRSRDR RR
Sbjct: 209 RHSGRDDTSRYDERPGPSPLPHRDRDRDRERERRERSRERDKERERR---RSRSRDRRRR 265

Query: 302 HRSRSRSHSRGHRRASRDRSAKYK 325
            RSR +   R  R  S+D+    K
Sbjct: 266 SRSRDKEERRRSRERSKDKDRDRK 289



 Score = 50.8 bits (120), Expect = 2e-06
 Identities = 36/109 (33%), Positives = 43/109 (39%), Gaps = 27/109 (24%)

Query: 234 EKQEKRNQDRLRRREEREREERLSRRSG-------SRTRD-------------------R 267
           ++  KR   R R R  RERE +   R G       S   D                    
Sbjct: 285 DRDRKRRSSRSRERARRERERKEELRGGGGDMAEPSEAGDAPPDDGPPGELGPDGPDGPE 344

Query: 268 RRSRSRDRRRRRSRSTSRERRKLSRSRSRDRHRRHRSRSRSHSRGHRRA 316
            + R RDR RRRS  + RERR+  R R RDR R H+   R   RG   A
Sbjct: 345 EKGRDRDRERRRSHRSERERRR-DRDRDRDRDREHKRGERGSERGRDEA 392



 Score = 45.8 bits (107), Expect = 5e-05
 Identities = 32/82 (39%), Positives = 39/82 (47%), Gaps = 6/82 (7%)

Query: 246 RREEREREERLSRRSGSRTRDRRRSRSRDRRRRRSRSTSRERRKLSRSRSRDRHRR---- 301
           RR   +   R S R  +   D R   S    R R R   RERR+ SR R ++R RR    
Sbjct: 200 RRGGADVNIRHSGRDDTSRYDERPGPSPLPHRDRDRDRERERRERSRERDKERERRRSRS 259

Query: 302 --HRSRSRSHSRGHRRASRDRS 321
              R RSRS  +  RR SR+RS
Sbjct: 260 RDRRRRSRSRDKEERRRSRERS 281



 Score = 35.4 bits (80), Expect = 0.070
 Identities = 21/56 (37%), Positives = 26/56 (46%), Gaps = 6/56 (10%)

Query: 237 EKRNQDRLRRREEREREERLSRRSGSRTRDRRRSRSRDRRRRRSRSTSRERRKLSR 292
           E++ +DR R R    R ER       R RDR R R RDR  +R    S   R  +R
Sbjct: 344 EEKGRDRDRERRRSHRSER------ERRRDRDRDRDRDREHKRGERGSERGRDEAR 393



 Score = 33.9 bits (76), Expect = 0.20
 Identities = 26/71 (36%), Positives = 32/71 (45%), Gaps = 7/71 (9%)

Query: 249 EREREERLSRRSGSRTRDRRRSRSRDRRRRRSRSTSRERRKLSRSRSRDRHRRHRSRSRS 308
           +R+RE R S RS    R+RRR R RDR R R      +R +    R RD  R       +
Sbjct: 349 DRDRERRRSHRS---ERERRRDRDRDRDRDR----EHKRGERGSERGRDEARGGGGGQDN 401

Query: 309 HSRGHRRASRD 319
              G    SRD
Sbjct: 402 GLEGLGNDSRD 412


>gi|42560244 peptidylprolyl isomerase G [Homo sapiens]
          Length = 754

 Score = 69.7 bits (169), Expect = 3e-12
 Identities = 77/276 (27%), Positives = 121/276 (43%), Gaps = 44/276 (15%)

Query: 70  DYEIASKERDLFFELDAMDHLESFIAECDRRTELAKKRLAETQEEISAEVSAKAEKVHEL 129
           D++  SKERD+    +  D  ++ +          KKR        S E S   E+  + 
Sbjct: 428 DHKSNSKERDIRRNSEKDDKYKNKV----------KKRAKSKSRSKSKEKSKSKERDSKH 477

Query: 130 NEEIGKLLAKAEQLGAEGNVDESQKIL----MEVEKVRAKKKEAEEEYRNSMPASSFQQQ 185
           N    K +    +     NV E +K       + E+ R+K+K  + E +++    S  ++
Sbjct: 478 NRNEEKRMRSRSKGRDHENVKEKEKQSDSKGKDQERSRSKEKSKQLESKSNEHDHSKSKE 537

Query: 186 KLRVCEVCSAYLGLHDNDRRLADHFGGKLHLGFIQIREKLDQLRKTVAEKQEKRNQDRLR 245
           K R  +  S          R  D   GK H    + RE+     ++   +    ++DR R
Sbjct: 538 KDRRAQSRS----------RECDITKGK-HSYNSRTRERSRSRDRSRRVRSRTHDRDRSR 586

Query: 246 RRE-EREREERLSRRSGSRTRDRR----RSRSRDRRRRRSRSTSRERRKLSRSRSRDRHR 300
            +E  R RE+   RR  SR+R+RR    RSRS+DRRRRR  S S ER + S+SR++D++R
Sbjct: 587 SKEYHRYREQEYRRRGRSRSRERRTPPGRSRSKDRRRRRRDSRSSEREE-SQSRNKDKYR 645

Query: 301 RHRSRSR-------------SHSRGHRRASRDRSAK 323
              S+S              S SR H  ++  R  K
Sbjct: 646 NQESKSSHRKENSESEKRMYSKSRDHNSSNNSREKK 681



 Score = 60.5 bits (145), Expect = 2e-09
 Identities = 64/255 (25%), Positives = 106/255 (41%), Gaps = 30/255 (11%)

Query: 94  IAECDRRTELAKKRLAETQEEISAEVSAKAEKVHELNEEIGKLLAKAEQLGAEGNVDESQ 153
           I E  R     K+R       +S   + K EK  ++ +   K  +K   +      D+  
Sbjct: 391 IKENQRSPVRVKERKITDHRNVSESPNRKNEKEKKVKDH--KSNSKERDIRRNSEKDDKY 448

Query: 154 KILMEVE---KVRAKKKEAEEEYRNSMPASSFQQQKLRVCEVCSAYLGLHD----NDRRL 206
           K  ++     K R+K KE  +        +  +++++R       +  + +    +D + 
Sbjct: 449 KNKVKKRAKSKSRSKSKEKSKSKERDSKHNRNEEKRMRSRSKGRDHENVKEKEKQSDSKG 508

Query: 207 ADHFGGKLHLGFIQIREKLDQLRKTVAEKQEKRNQDRLR-------------RREERERE 253
            D    +      Q+  K ++   + ++++++R Q R R             R  ER R 
Sbjct: 509 KDQERSRSKEKSKQLESKSNEHDHSKSKEKDRRAQSRSRECDITKGKHSYNSRTRERSRS 568

Query: 254 ERLSRRSGSRTRDRRRSRSRD-------RRRRRSRSTSRERR-KLSRSRSRDRHRRHRSR 305
              SRR  SRT DR RSRS++         RRR RS SRERR    RSRS+DR RR R  
Sbjct: 569 RDRSRRVRSRTHDRDRSRSKEYHRYREQEYRRRGRSRSRERRTPPGRSRSKDRRRRRRDS 628

Query: 306 SRSHSRGHRRASRDR 320
             S     +  ++D+
Sbjct: 629 RSSEREESQSRNKDK 643



 Score = 44.7 bits (104), Expect = 1e-04
 Identities = 31/100 (31%), Positives = 55/100 (55%), Gaps = 14/100 (14%)

Query: 236 QEKRNQDRLRRREEREREERLSRRSGSRTRDRRRSRSRDRRRR---------RSRSTSRE 286
           +EKR + R + R+    +E+  ++S S+ +D+ RSRS+++ ++          S+S  ++
Sbjct: 481 EEKRMRSRSKGRDHENVKEK-EKQSDSKGKDQERSRSKEKSKQLESKSNEHDHSKSKEKD 539

Query: 287 RRKLSRSRSRDRHR-RHRSRSRSHSRGHRRASRDRSAKYK 325
           RR  SRSR  D  + +H   SR+  R     SRDRS + +
Sbjct: 540 RRAQSRSRECDITKGKHSYNSRTRERSR---SRDRSRRVR 576



 Score = 43.1 bits (100), Expect = 3e-04
 Identities = 26/103 (25%), Positives = 53/103 (51%), Gaps = 10/103 (9%)

Query: 229 RKTVAEKQEKRNQDRLRRREER---EREERLSRRSGSRTRDRRRSRSRDRRRRRSRSTSR 285
           RK   EK+ K ++   + R+ R   E++++   +   R + + RS+S+++ + + R +  
Sbjct: 418 RKNEKEKKVKDHKSNSKERDIRRNSEKDDKYKNKVKKRAKSKSRSKSKEKSKSKERDSKH 477

Query: 286 ERRKLSRSRSRDRHRRHRS----RSRSHSRG---HRRASRDRS 321
            R +  R RSR + R H +      +S S+G    R  S+++S
Sbjct: 478 NRNEEKRMRSRSKGRDHENVKEKEKQSDSKGKDQERSRSKEKS 520



 Score = 42.7 bits (99), Expect = 4e-04
 Identities = 31/102 (30%), Positives = 54/102 (52%), Gaps = 11/102 (10%)

Query: 235 KQEKRNQDRLRRREEREREERLSRRSGSRTRDRRRSRSRDR-RRRRSRS-----TSRERR 288
           K++++  D   + +ER R +  S++  S++ +   S+S+++ RR +SRS     T  +  
Sbjct: 498 KEKEKQSDSKGKDQERSRSKEKSKQLESKSNEHDHSKSKEKDRRAQSRSRECDITKGKHS 557

Query: 289 KLSRSRSR--DRHRRHRSRSRSHSRGHRRAS---RDRSAKYK 325
             SR+R R   R R  R RSR+H R   R+    R R  +Y+
Sbjct: 558 YNSRTRERSRSRDRSRRVRSRTHDRDRSRSKEYHRYREQEYR 599



 Score = 37.0 bits (84), Expect = 0.024
 Identities = 31/100 (31%), Positives = 44/100 (44%), Gaps = 6/100 (6%)

Query: 228 LRKTVAEKQEKRNQDRLRRREEREREERLSRRSGSR----TRDRRRSRSRDRRRRR--SR 281
           +RK+  +  EK  ++R R RE           S  R    TR  R+ + R  RR R  SR
Sbjct: 287 MRKSPPKADEKERKNRERERERECNPPNSQPASYQRRLLVTRSGRKIKGRGPRRYRTPSR 346

Query: 282 STSRERRKLSRSRSRDRHRRHRSRSRSHSRGHRRASRDRS 321
           S SR+R + S +    R    R++    S G R    D+S
Sbjct: 347 SRSRDRFRRSETPPHWRQEMQRAQRMRVSSGERWIKGDKS 386



 Score = 33.9 bits (76), Expect = 0.20
 Identities = 18/77 (23%), Positives = 37/77 (48%), Gaps = 6/77 (7%)

Query: 246 RREEREREERLSRRSGSRTRDRRRSRSRDRRRRRSRSTSRERRKLSRSRSRDRHRRHRSR 305
           ++EE++R +  S  S S +     S S+      S S S +    +  +S+ R ++HR  
Sbjct: 184 KKEEKKRHKSSSSSSSSSSDSDSSSDSQ------SSSDSSDSESATEEKSKKRKKKHRKN 237

Query: 306 SRSHSRGHRRASRDRSA 322
           SR H +  ++  + + +
Sbjct: 238 SRKHKKEKKKRKKSKKS 254



 Score = 30.8 bits (68), Expect = 1.7
 Identities = 19/92 (20%), Positives = 40/92 (43%), Gaps = 7/92 (7%)

Query: 239 RNQDRLRR-------REEREREERLSRRSGSRTRDRRRSRSRDRRRRRSRSTSRERRKLS 291
           R++DR RR       R+E +R +R+   SG R     +S   + +  +      + RK++
Sbjct: 348 RSRDRFRRSETPPHWRQEMQRAQRMRVSSGERWIKGDKSELNEIKENQRSPVRVKERKIT 407

Query: 292 RSRSRDRHRRHRSRSRSHSRGHRRASRDRSAK 323
             R+       ++      + H+  S++R  +
Sbjct: 408 DHRNVSESPNRKNEKEKKVKDHKSNSKERDIR 439


>gi|4826690 DEAH (Asp-Glu-Ala-His) box polypeptide 8 [Homo sapiens]
          Length = 1220

 Score = 68.6 bits (166), Expect = 7e-12
 Identities = 43/105 (40%), Positives = 56/105 (53%), Gaps = 8/105 (7%)

Query: 221 IREKLDQLRKTVAEKQEKRNQDRLRRREEREREERLSRRSGSRTRDRRRSRSRDRRRRRS 280
           ++  +D L++  A       Q++ R  E R+R ++  R   SR+RDR R R RDR R R 
Sbjct: 139 VKVAVDVLKELEALMPSAAGQEKQRDAEHRDRTKKKKR---SRSRDRNRDRDRDRERNRD 195

Query: 281 RSTSRERRKLSRSRSRDRHR-----RHRSRSRSHSRGHRRASRDR 320
           R   R  R  SRSRSR R R     R+RSRSRS S    R  RD+
Sbjct: 196 RDHKRRHRSRSRSRSRTRERNKVKSRYRSRSRSQSPPKDRKDRDK 240



 Score = 48.5 bits (114), Expect = 8e-06
 Identities = 31/88 (35%), Positives = 46/88 (52%), Gaps = 11/88 (12%)

Query: 223 EKLDQLRKTVAEKQEKRNQDRLRRRE-----EREREERLSRRSGSRTRDRRRSRSRDRRR 277
           E  D+ +K    +   RN+DR R RE     + +R  R   RS SRTR+R + +SR R R
Sbjct: 166 EHRDRTKKKKRSRSRDRNRDRDRDRERNRDRDHKRRHRSRSRSRSRTRERNKVKSRYRSR 225

Query: 278 RRSRSTSRERRKLSR------SRSRDRH 299
            RS+S  ++R+   +       R RD+H
Sbjct: 226 SRSQSPPKDRKDRDKYGERNLDRWRDKH 253


>gi|239754909 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 245

 Score = 65.9 bits (159), Expect = 5e-11
 Identities = 59/258 (22%), Positives = 111/258 (43%), Gaps = 30/258 (11%)

Query: 52  TRMDLGECTKIHDLALRADY--EIASKERDLFFELDAMDHLESFIAECDRRTELAKKRLA 109
           T + +  C+ I     +  +  EI  +ER++    +     ES   E  +     +KR  
Sbjct: 15  TELQMVSCSHISKPCTQPGWQSEIREREREIETRKEGKKERES---ERKKERREREKRKR 71

Query: 110 ETQEEISAEVSAKAEKVHELNEEIGKLLAKAEQLGAEGNVDESQKILMEVEKVRAKKKEA 169
           E ++E   E   K +K     EE  +   + E+   EG            EK + KKKE 
Sbjct: 72  EREKERKRERGKKEKKGERKKEERERKKRRREKENKEGE-----------EKEKRKKKEK 120

Query: 170 EEEYRNSMPASSFQQQKLRVCEVCSAYLGLHDNDRRLADHFGGKLHLGFIQIREKLDQLR 229
           +E  R S      ++++ R  E         + +R+  +    +      + +E+  + R
Sbjct: 121 KERGRTSKEGKERERKEERKREERK------ERERKKEEREKER------ERKERKKRER 168

Query: 230 KTVAEKQEKRNQDRLRRREEREREERLSRRSGSRTRDRRRSRSRDRRRRRSRSTSRERRK 289
           K V EK+E+R +   + R++RER  +   R   R R  RR R ++R+++  R   R++ +
Sbjct: 169 KQVGEKEEERKEKERKERKKRERNRK--ERKKERERKERRERKKERKKKEERKKERQKDR 226

Query: 290 LSRSRSRDRHRRHRSRSR 307
            +  R ++R +R R   +
Sbjct: 227 QTNWREKERGKRERKERK 244



 Score = 55.1 bits (131), Expect = 8e-08
 Identities = 27/105 (25%), Positives = 53/105 (50%), Gaps = 1/105 (0%)

Query: 222 REKLDQLRKTVAEKQEKRNQDRLRRREEREREERLSRRSGSRTRDRRRSRSRDRRRRRSR 281
           +EK  + +K   E++++R +   +  EE+E+ ++  ++   RT    + R R   R+R  
Sbjct: 84  KEKKGERKKEERERKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREE 143

Query: 282 STSRERRKLSRSRSRDR-HRRHRSRSRSHSRGHRRASRDRSAKYK 325
              RER+K  R + R+R  R+ R R +   +   R  ++R  + K
Sbjct: 144 RKERERKKEEREKERERKERKKRERKQVGEKEEERKEKERKERKK 188



 Score = 52.0 bits (123), Expect = 7e-07
 Identities = 29/104 (27%), Positives = 51/104 (49%), Gaps = 2/104 (1%)

Query: 222 REKLDQLRKTVAEKQEKRNQDRLRRREEREREERLSRRSGSRTRDRRRSRSRDRRRRRSR 281
           +EK  +  K    +  K  ++R  R+EER+REER  R      R++ R R   ++R R +
Sbjct: 112 KEKRKKKEKKERGRTSKEGKER-ERKEERKREERKERERKKEEREKERERKERKKRERKQ 170

Query: 282 STSRERRKLSRSRSRDRHRRHRSRSRSHSRGHRRASRDRSAKYK 325
              +E  +  + R ++R +R R+R        R+  R+R  + K
Sbjct: 171 VGEKEEERKEKER-KERKKRERNRKERKKERERKERRERKKERK 213



 Score = 50.1 bits (118), Expect = 3e-06
 Identities = 29/105 (27%), Positives = 51/105 (48%), Gaps = 3/105 (2%)

Query: 222 REKLDQLRKTVAEKQEKRNQDRLRRREER-EREERLSRRSGSRTRDRRRSRSRDRRRRRS 280
           +EK ++ R +   K+ +R ++R  +REER ERE +   R   R R  R+ R R +   + 
Sbjct: 118 KEKKERGRTSKEGKERERKEER--KREERKERERKKEEREKERERKERKKRERKQVGEKE 175

Query: 281 RSTSRERRKLSRSRSRDRHRRHRSRSRSHSRGHRRASRDRSAKYK 325
                + RK  + R R+R  R + R R   R  ++  + +  + K
Sbjct: 176 EERKEKERKERKKRERNRKERKKERERKERRERKKERKKKEERKK 220



 Score = 49.7 bits (117), Expect = 4e-06
 Identities = 26/107 (24%), Positives = 51/107 (47%), Gaps = 4/107 (3%)

Query: 220 QIREKLDQLRKTVAEKQEKRNQDRLRRREEREREERLSRRSGSRTRDRRRSRSRDRRRRR 279
           +IRE+    R+    K+ K+ ++  R++E RERE+R   R   R R+R +   +  R++ 
Sbjct: 37  EIRERE---REIETRKEGKKERESERKKERREREKRKREREKERKRERGKKEKKGERKKE 93

Query: 280 SRSTSRERRKLSRSRSRDRHRRHRSRSRSHSRGHRRA-SRDRSAKYK 325
            R   + RR+       ++ +R +   +   R  +    R+R  + K
Sbjct: 94  ERERKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERK 140



 Score = 48.1 bits (113), Expect = 1e-05
 Identities = 28/130 (21%), Positives = 62/130 (47%), Gaps = 6/130 (4%)

Query: 199 LHDNDRRLADHFGGKLHLGFIQIREKLD-QLRKTVAEKQEKRNQDRLRRREEREREERLS 257
           + + +R +     GK      + +E+ + + RK   EK+ KR + +  ++ ER++EER  
Sbjct: 38  IREREREIETRKEGKKERESERKKERREREKRKREREKERKRERGKKEKKGERKKEER-E 96

Query: 258 RRSGSRTRDRRRSRSRDRRRRRSRS----TSRERRKLSRSRSRDRHRRHRSRSRSHSRGH 313
           R+   R ++ +    +++R+++ +     TS+E ++  R   R R  R     +   R  
Sbjct: 97  RKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKERERKKEEREK 156

Query: 314 RRASRDRSAK 323
            R  ++R  +
Sbjct: 157 ERERKERKKR 166



 Score = 44.7 bits (104), Expect = 1e-04
 Identities = 23/109 (21%), Positives = 51/109 (46%), Gaps = 5/109 (4%)

Query: 222 REKLDQLRKTVAEKQEKRNQDRLRRREEREREERLSRRSGSRTRDRRRSRSRDRRRRRSR 281
           R+K ++ RK    ++E +  +   +R+++E++ER       + R+R+  R R+ R+ R R
Sbjct: 90  RKKEERERKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKERER 149

Query: 282 -----STSRERRKLSRSRSRDRHRRHRSRSRSHSRGHRRASRDRSAKYK 325
                   RER++  +   +    +   R     +  ++  R+R  + K
Sbjct: 150 KKEEREKERERKERKKRERKQVGEKEEERKEKERKERKKRERNRKERKK 198



 Score = 43.5 bits (101), Expect = 3e-04
 Identities = 24/106 (22%), Positives = 45/106 (42%), Gaps = 15/106 (14%)

Query: 235 KQEKRNQDRLRRR--EEREREERLSRRSGSRTRDRRRSRSRDRRRRRSRSTSRERRKLSR 292
           K+E+R +++ +R   +ER+RE     + G R ++ R  + R R +       +E+RK   
Sbjct: 60  KKERREREKRKREREKERKRERGKKEKKGERKKEERERKKRRREKENKEGEEKEKRKKKE 119

Query: 293 SRSRDR-------------HRRHRSRSRSHSRGHRRASRDRSAKYK 325
            + R R              +R   + R   +  R   R+R  + K
Sbjct: 120 KKERGRTSKEGKERERKEERKREERKERERKKEEREKERERKERKK 165


>gi|166235169 PRP38 pre-mRNA processing factor 38 (yeast) domain
           containing B [Homo sapiens]
          Length = 546

 Score = 65.9 bits (159), Expect = 5e-11
 Identities = 66/234 (28%), Positives = 104/234 (44%), Gaps = 10/234 (4%)

Query: 100 RTELAKKRLAETQEEISAEVSAKAEKV--HELNEEIGKLLAKAEQLGAEGNVDESQKILM 157
           R    KK   E  EEI   V  +  +     L+       +++     EG+   S    +
Sbjct: 236 RPRKIKKDGKEGAEEIDRHVERRRSRSPRRSLSPRRSPRRSRSRSHHREGHGSSSFDREL 295

Query: 158 EVEKVRAK----KKEAEEEYRNSMPAS-SFQQQKLRVCEVCSAYLGLHDN--DRRLADHF 210
           E EK R +     KE E+E R S       ++++ R  E   +     D   DRR  D  
Sbjct: 296 EREKERQRLEREAKEREKERRRSRSIDRGLERRRSRSRERHRSRSRSRDRKGDRRDRDRE 355

Query: 211 GGKLHLGFIQIREKLDQLRKTVAEKQEKRNQDRLRRREER-EREERLSRRSGSRTRDRRR 269
             K +    +     D+ R    EK+ +R+++R + +  R E EE+  +      R R  
Sbjct: 356 REKENERGRRRDRDYDKERGNEREKERERSRERSKEQRSRGEVEEKKHKEDKDDRRHRDD 415

Query: 270 SRSRDRRRRRSRSTSRERRKLSRSRSRDRHRRHRSRSRSHSRGHRRASRDRSAK 323
            R   + ++ SRS SRER+  SRSRSR+  +R RSRS+  S  H+  S+++S K
Sbjct: 416 KRDSKKEKKHSRSRSRERKHRSRSRSRNAGKRSRSRSKEKSSKHKNESKEKSNK 469



 Score = 64.7 bits (156), Expect = 1e-10
 Identities = 64/264 (24%), Positives = 114/264 (43%), Gaps = 35/264 (13%)

Query: 90  LESFIAECDRRTELAKKRLAETQEEISAEVSAKAEKVHELNEEIGKLLAKAEQLGAEGNV 149
           L SF+ + +  + L  +     Q+ I  ++  +  K+ +  +E       AE++      
Sbjct: 204 LRSFLTKLEWFSTLFPRIPVPVQKNIDQQIKTRPRKIKKDGKE------GAEEIDRHVER 257

Query: 150 DESQKILMEVEKVRA-KKKEAEEEYRNSMPASSFQQQKLRVCEV--CSAYLGLHDNDRRL 206
             S+     +   R+ ++  +   +R    +SSF ++  R  E           + +RR 
Sbjct: 258 RRSRSPRRSLSPRRSPRRSRSRSHHREGHGSSSFDRELEREKERQRLEREAKEREKERRR 317

Query: 207 ADHFGGKLHLGFIQIREKLDQLRKTVAEKQEKRNQDRLRRREEREREERLSR-----RSG 261
           +      L     + RE+     ++   K ++R++DR  R +E ER  R  R     R  
Sbjct: 318 SRSIDRGLERRRSRSRERHRSRSRSRDRKGDRRDRDR-EREKENERGRRRDRDYDKERGN 376

Query: 262 SRTRDRRRSRSR--------------------DRRRRRSRSTSRERRKLSRSRSRDRHRR 301
            R ++R RSR R                    DRR R  +  S++ +K SRSRSR+R  R
Sbjct: 377 EREKERERSRERSKEQRSRGEVEEKKHKEDKDDRRHRDDKRDSKKEKKHSRSRSRERKHR 436

Query: 302 HRSRSRSHSRGHRRASRDRSAKYK 325
            RSRSR+  +  R  S+++S+K+K
Sbjct: 437 SRSRSRNAGKRSRSRSKEKSSKHK 460



 Score = 56.6 bits (135), Expect = 3e-08
 Identities = 37/114 (32%), Positives = 62/114 (54%), Gaps = 12/114 (10%)

Query: 222 REKLDQLRKTVAEKQEKRNQDRLRRREEREREERLSRRSGSRTRDR---RRSRSRDRRRR 278
           R   D  R +  EK+  R++ R R+   R R     +RS SR++++    ++ S+++  +
Sbjct: 410 RRHRDDKRDSKKEKKHSRSRSRERKHRSRSRSRNAGKRSRSRSKEKSSKHKNESKEKSNK 469

Query: 279 RSRSTSRER-------RKLSRSRSRDRHR-RHRSRSRSHSRGHRRASRDRSAKY 324
           RSRS S+ R       +K   S S+++ R R RS+ RSH R H   S+D+S K+
Sbjct: 470 RSRSGSQGRTDSVEKSKKREHSPSKEKSRKRSRSKERSHKRDH-SDSKDQSDKH 522



 Score = 55.1 bits (131), Expect = 8e-08
 Identities = 33/95 (34%), Positives = 52/95 (54%), Gaps = 9/95 (9%)

Query: 222 REKLDQLRKTVAEKQEKRNQDRLRRREEREREERLSRRSGSRTRDRRRSRSRDRRRRRSR 281
           R K  + R  V EK+ K ++D  R R+++        R   + +   RSRSR+ R+ RSR
Sbjct: 388 RSKEQRSRGEVEEKKHKEDKDDRRHRDDK--------RDSKKEKKHSRSRSRE-RKHRSR 438

Query: 282 STSRERRKLSRSRSRDRHRRHRSRSRSHSRGHRRA 316
           S SR   K SRSRS+++  +H++ S+  S    R+
Sbjct: 439 SRSRNAGKRSRSRSKEKSSKHKNESKEKSNKRSRS 473



 Score = 45.4 bits (106), Expect = 7e-05
 Identities = 46/210 (21%), Positives = 89/210 (42%), Gaps = 34/210 (16%)

Query: 98  DRRTELAKKRLAETQEEISAEVSAKAEKVHELNEEIGKLLAKAEQLGAEGNVDESQ-KIL 156
           DR  E   +R      +   E   + EK  E + E      ++++  + G V+E + K  
Sbjct: 353 DREREKENERGRRRDRDYDKERGNEREKERERSRE------RSKEQRSRGEVEEKKHKED 406

Query: 157 MEVEKVRAKKKEAEEEYRNSMPASSFQQQKLRVCEVCSAYLGLHDNDRRLADHFGGKLHL 216
            +  + R  K+++++E ++S   S  ++ + R     S   G     R            
Sbjct: 407 KDDRRHRDDKRDSKKEKKHSRSRSRERKHRSRSR---SRNAGKRSRSRS----------- 452

Query: 217 GFIQIREKLDQLRKTVAEKQEKRNQDRLRRREEREREERLSRRSGSRTRDRRRSRSRDRR 276
                +EK  + +    EK  KR++   + R +   + +    S S+ + R+RSRS++R 
Sbjct: 453 -----KEKSSKHKNESKEKSNKRSRSGSQGRTDSVEKSKKREHSPSKEKSRKRSRSKERS 507

Query: 277 RRRSRSTSRERRKLSRSRSRDRHRRHRSRS 306
            +R  S S+++         D+H R RS+S
Sbjct: 508 HKRDHSDSKDQS--------DKHDRRRSQS 529



 Score = 38.5 bits (88), Expect = 0.008
 Identities = 53/223 (23%), Positives = 95/223 (42%), Gaps = 25/223 (11%)

Query: 98  DRRTELAKKRLAETQEEISAEVSAKAEKVHELNEEIGKLLAKAEQLGAEGNVDESQKILM 157
           DR  E  + R  E     S     K ++     E       K  + G   + D  ++   
Sbjct: 322 DRGLERRRSRSRERHRSRSRSRDRKGDRRDRDRER-----EKENERGRRRDRDYDKERGN 376

Query: 158 EVEKVRAKKKEAEEEYRNSMPASSFQQQKLRVCEVCSAYLGLHDNDRRLADHFGGKLHLG 217
           E EK R + +E  +E R+       + ++ +           H +D+R  D    K H  
Sbjct: 377 EREKERERSRERSKEQRSRGEVEEKKHKEDKDDR-------RHRDDKR--DSKKEKKH-S 426

Query: 218 FIQIREKLDQLR---KTVAEKQEKRNQDRLRRREEREREERLSR-RSGSRTRDRRRSRSR 273
             + RE+  + R   +   ++   R++++  + +   +E+   R RSGS    + R+ S 
Sbjct: 427 RSRSRERKHRSRSRSRNAGKRSRSRSKEKSSKHKNESKEKSNKRSRSGS----QGRTDSV 482

Query: 274 DRRRRRSRSTSRER-RKLSRSRSRDRHRRHRSRSRSHSRGHRR 315
           ++ ++R  S S+E+ RK SRS+ R  H+R  S S+  S  H R
Sbjct: 483 EKSKKREHSPSKEKSRKRSRSKERS-HKRDHSDSKDQSDKHDR 524


>gi|55741709 RNA binding motif protein 25 [Homo sapiens]
          Length = 843

 Score = 64.7 bits (156), Expect = 1e-10
 Identities = 55/178 (30%), Positives = 82/178 (46%), Gaps = 22/178 (12%)

Query: 163 RAKKKEAEEEYRNSMPASSFQQQKLRVCEVCSAYLGLHDNDRRLADHFGGKL---HLGFI 219
           R KKKE +E+     P +      L   E  +A + + ++ R L      K    H    
Sbjct: 234 RKKKKEKKEDIFRRFPVAPLIPYPLITKEDINA-IEMEEDKRDLISREISKFRDTHKKLE 292

Query: 220 QIREKLDQLRKTVAEKQEKRNQDRLRRREEREREERLSR-----------RSGSRTRDRR 268
           + + K ++ R+ + +++ +R ++R R RE RERE    R           R   R RDR 
Sbjct: 293 EEKGKKEKERQEIEKERRERERERERERERREREREREREREREKEKERERERERDRDRD 352

Query: 269 RSRSRDRRRRRSRSTSRERRKLS-----RSRSRDRHR-RHRSRSRSHSRGHRRASRDR 320
           R++ RDR R R R   R+R + S     RSRSR++ R R R R R   R  R   R+R
Sbjct: 353 RTKERDRDRDRERDRDRDRERSSDRNKDRSRSREKSRDRERERERERER-ERERERER 409



 Score = 63.9 bits (154), Expect = 2e-10
 Identities = 65/259 (25%), Positives = 107/259 (41%), Gaps = 25/259 (9%)

Query: 88  DHLESFIAECDRRTELAKKRLAETQEEISAEVSAKAE--------KVHELNEEIGK---- 135
           D  E+   E  RR ++ K  +     E S+E++A ++        K  E  E+I +    
Sbjct: 191 DDEEALDEETKRRDQMIKGAIEVLIREYSSELNAPSQESDSHPRKKKKEKKEDIFRRFPV 250

Query: 136 -------LLAKAEQLGAEGNVDESQKILMEVEKVRAKKKEAEEEYRNSMPASSFQQQKLR 188
                  L+ K +    E   D+   I  E+ K R   K+ EEE           +++ R
Sbjct: 251 APLIPYPLITKEDINAIEMEEDKRDLISREISKFRDTHKKLEEEKGKKEKERQEIEKERR 310

Query: 189 VCEVCSAYLGLHDNDRRLADHFGGKLHLGFIQIREKLDQLRKTVAEKQEKRNQDRLRRRE 248
             E         + +RR  +    +      +   + ++ R    ++ ++R++DR R R+
Sbjct: 311 ERERERE----RERERREREREREREREREKEKERERERERDRDRDRTKERDRDRDRERD 366

Query: 249 EREREERLSRRSGSRTRDRRRSRSRDRRRRRSRSTSRER-RKLSRSRSRDRHR-RHRSRS 306
                ER S R+  R+R R +SR R+R R R R   RER R+  R R R+R R R R R 
Sbjct: 367 RDRDRERSSDRNKDRSRSREKSRDRERERERERERERERERERERERERERERERERERE 426

Query: 307 RSHSRGHRRASRDRSAKYK 325
           +   R       D   + K
Sbjct: 427 KDKKRDREEDEEDAYERRK 445



 Score = 60.5 bits (145), Expect = 2e-09
 Identities = 55/219 (25%), Positives = 95/219 (43%), Gaps = 29/219 (13%)

Query: 111 TQEEISAEVSAKAEKVHELNEEIGKLLAKAEQLGAEGNVDESQKILMEVEKVRAKKKEAE 170
           T+E+I+A +  + +K   ++ EI K     ++L  E    E ++  +E E+ R +++E E
Sbjct: 260 TKEDINA-IEMEEDKRDLISREISKFRDTHKKLEEEKGKKEKERQEIEKER-RERERERE 317

Query: 171 EEYRNSMPASSFQQQKLRVCEVCSAYLGLHDNDRRLADHFGGKLHLGFIQIREKLDQLRK 230
            E          ++++ R  E         D DR                     D+ ++
Sbjct: 318 RERERREREREREREREREKEKERERERERDRDR---------------------DRTKE 356

Query: 231 TVAEKQEKRNQDRLRRREEREREERLSRRSGSRTRDRRRSRSRDRRRRRSRSTSRER-RK 289
              ++  +R++DR R R     ++R   RS  ++RDR R R R+R R R R   RER R+
Sbjct: 357 RDRDRDRERDRDRDRERSSDRNKDR--SRSREKSRDRERERERERERERERERERERERE 414

Query: 290 LSRSRSRDRHR---RHRSRSRSHSRGHRRASRDRSAKYK 325
             R R R+R R   + R R       + R   +R  + K
Sbjct: 415 REREREREREREKDKKRDREEDEEDAYERRKLERKLREK 453



 Score = 45.8 bits (107), Expect = 5e-05
 Identities = 53/223 (23%), Positives = 98/223 (43%), Gaps = 33/223 (14%)

Query: 110 ETQEEISAEVSAKAEKVHELNEEIGKLLAKAEQLGAEGNVDESQKILMEVEKVRAKKKEA 169
           + ++ IS E+S   +   +L EE GK   + +++  E    E ++   E E+ R +++  
Sbjct: 272 DKRDLISREISKFRDTHKKLEEEKGKKEKERQEIEKERRERERER---ERERERRERERE 328

Query: 170 EEEYRNSMPASSFQQQKLRVCEVCSAYLGLHDNDR---------RLADHFGGKLHLGFIQ 220
            E  R        ++++ R  +         D DR         R +D    +      +
Sbjct: 329 REREREREKEKERERERERDRDRDRTKERDRDRDRERDRDRDRERSSDRNKDRS-----R 383

Query: 221 IREKL-DQLRKTVAEKQEKRNQDRLRRRE---EREREERLSRRSGSRTRDRRRSRSRDRR 276
            REK  D+ R+   E++ +R ++R R RE   ERERE           R+R R + + R 
Sbjct: 384 SREKSRDRERERERERERERERERERERERERERERE-----------REREREKDKKRD 432

Query: 277 RRRSRSTSRERRKLSRSRSRDRHRRHRSRSRSHSRGHRRASRD 319
           R      + ERRKL R + R++   ++ R ++     R+ +R+
Sbjct: 433 REEDEEDAYERRKLER-KLREKEAAYQERLKNWEIRERKKTRE 474



 Score = 34.3 bits (77), Expect = 0.16
 Identities = 46/214 (21%), Positives = 83/214 (38%), Gaps = 29/214 (13%)

Query: 96  ECDRRTELAKKRLAETQEEISAEVSAKAEKVHELNEEIGKLLAKAEQLGAEGNVDESQKI 155
           E +R  E  ++R  E + E   E     ++  E +EE      K E+   E      +++
Sbjct: 402 EREREREREREREREREREREREREKDKKRDREEDEEDAYERRKLERKLREKEAAYQERL 461

Query: 156 ----LMEVEKVRAKKKEAEEEYRNSMPASSFQQQKLRVCEVCSAYLGLHDNDRRLADHFG 211
               + E +K R  +KEAE E          +++  +  +    +L  +D+DR    ++ 
Sbjct: 462 KNWEIRERKKTREYEKEAEREEER-------RREMAKEAKRLKEFLEDYDDDRDDPKYYR 514

Query: 212 GKLHLGFIQIREKLDQLRKTVAEKQEKRNQDRLRRREERE--REERLSRRSGSRTRDRRR 269
           G      ++ REK          + E   +DR R +EE E  R+  L+        + +R
Sbjct: 515 GSALQKRLRDREK----------EMEADERDRKREKEELEEIRQRLLAEGHPDPDAELQR 564

Query: 270 SRSRDRRRRRSR------STSRERRKLSRSRSRD 297
                 RRR+ +      S   E  K  +   R+
Sbjct: 565 MEQEAERRRQPQIKQEPESEEEEEEKQEKEEKRE 598



 Score = 31.6 bits (70), Expect = 1.0
 Identities = 27/112 (24%), Positives = 45/112 (40%), Gaps = 26/112 (23%)

Query: 227 QLRKTVAEKQEKRNQDRLRRREEREREE-RLSRRSGSRTRDRRRSRSRDRRR-------- 277
           +L + + EK E   Q+RL+  E RER++ R   +   R  +RRR  +++ +R        
Sbjct: 445 KLERKLREK-EAAYQERLKNWEIRERKKTREYEKEAEREEERRREMAKEAKRLKEFLEDY 503

Query: 278 ----------------RRSRSTSRERRKLSRSRSRDRHRRHRSRSRSHSRGH 313
                           +R R   +E     R R R++      R R  + GH
Sbjct: 504 DDDRDDPKYYRGSALQKRLRDREKEMEADERDRKREKEELEEIRQRLLAEGH 555



 Score = 28.9 bits (63), Expect = 6.5
 Identities = 20/99 (20%), Positives = 44/99 (44%), Gaps = 8/99 (8%)

Query: 100 RTELAKKRLAETQEEISAEVSAKAEKVHELNEEIGKLLAKA--------EQLGAEGNVDE 151
           R    +KRL + ++E+ A+   +  +  EL E   +LLA+         +++  E     
Sbjct: 514 RGSALQKRLRDREKEMEADERDRKREKEELEEIRQRLLAEGHPDPDAELQRMEQEAERRR 573

Query: 152 SQKILMEVEKVRAKKKEAEEEYRNSMPASSFQQQKLRVC 190
             +I  E E    ++++ E+E +   P    ++ + + C
Sbjct: 574 QPQIKQEPESEEEEEEKQEKEEKREEPMEEEEEPEQKPC 612


>gi|239749449 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 275

 Score = 64.7 bits (156), Expect = 1e-10
 Identities = 33/102 (32%), Positives = 59/102 (57%), Gaps = 3/102 (2%)

Query: 222 REKLDQLRKTVAEKQEKRNQDRLRRREEREREERLSRRSGSRTRDRRRSRSRDRRRRRSR 281
           REK  + RK   +K+E++ + R  R++++ER+ER   R   + R+R+R + R ++RR+ R
Sbjct: 90  REKERRKRKKEKKKRERKQRGRRERKKKKERKER--ERENKQRRERKRKKRRKKKRRKER 147

Query: 282 STSRERRKLSRSRSRDRHRRHRSRSRSHSRGHRRASRDRSAK 323
              +ER K  R R + R +  R + R  +R  R+  R+R  +
Sbjct: 148 KREKERGKRERKRKK-RKKEEREKKRERNRKERKKERERKER 188



 Score = 58.9 bits (141), Expect = 6e-09
 Identities = 28/105 (26%), Positives = 56/105 (53%), Gaps = 3/105 (2%)

Query: 222 REKLDQLRKTVAEKQEKRNQDRLRRREEREREERLSRRSGSRTRDRRRSRSRDRRRRRSR 281
           +EK  + ++   +++E++ ++R ++R+ER  +ER  R+   + R+R++   R+R++++ R
Sbjct: 61  KEKKKRKKRERGKERERKRKEREKQRKERREKERRKRKKEKKKRERKQRGRRERKKKKER 120

Query: 282 STSRERRKLSRSRSRDRHR---RHRSRSRSHSRGHRRASRDRSAK 323
                  K  R R R + R   R + R R   RG R   R +  K
Sbjct: 121 KERERENKQRRERKRKKRRKKKRRKERKREKERGKRERKRKKRKK 165



 Score = 57.8 bits (138), Expect = 1e-08
 Identities = 28/105 (26%), Positives = 55/105 (52%), Gaps = 1/105 (0%)

Query: 222 REKLDQLRKTVAEKQEKRNQDRLRRREEREREERLSRRSGSRTRDRRRSRSRDRRRRRSR 281
           RE+  + R+   E++ +R +   ++R++RER +   R+   R + R+  R ++RR+R+  
Sbjct: 41  REREKRKREREKERKRERGKKEKKKRKKRERGKERERKRKEREKQRKERREKERRKRKKE 100

Query: 282 STSRERRKLS-RSRSRDRHRRHRSRSRSHSRGHRRASRDRSAKYK 325
              RER++   R R + + R+ R R     R  +R  R +  + K
Sbjct: 101 KKKRERKQRGRRERKKKKERKERERENKQRRERKRKKRRKKKRRK 145



 Score = 56.6 bits (135), Expect = 3e-08
 Identities = 45/232 (19%), Positives = 92/232 (39%), Gaps = 34/232 (14%)

Query: 94  IAECDRRTELAKKRLAETQEEISAEVSAKAEKVHELNEEIGKLLAKAEQLGAEGNVDESQ 153
           +  C   ++   +R +E ++E       K E+  E   E GK   K  +    G   E +
Sbjct: 19  MVSCSHISKPCTQRESERKKERREREKRKREREKERKRERGKKEKKKRKKRERGKERERK 78

Query: 154 KILMEVEKVRAKKKEAEEEYRNSMPASSFQQQKLRVCEVCSAYLGLHDNDRRLADHFGGK 213
           +   E EK R +++E E   R        ++Q+                           
Sbjct: 79  R--KEREKQRKERREKERRKRKKEKKKRERKQR--------------------------- 109

Query: 214 LHLGFIQIREKLDQLRKTVAEKQEKRNQDRLRRREEREREERLSRRSGSRTRDR--RRSR 271
              G  + ++K ++  +    KQ +  + + RR+++R +E +  +  G R R R  R+  
Sbjct: 110 ---GRRERKKKKERKERERENKQRRERKRKKRRKKKRRKERKREKERGKRERKRKKRKKE 166

Query: 272 SRDRRRRRSRSTSRERRKLSRSRSRDRHRRHRSRSRSHSRGHRRASRDRSAK 323
            R+++R R+R   ++ R+    R R + R+   R +   +  R+  R   ++
Sbjct: 167 EREKKRERNRKERKKERERKERRERKKERKKERRKKKERKKDRKTDRQTDSQ 218



 Score = 50.4 bits (119), Expect = 2e-06
 Identities = 22/94 (23%), Positives = 48/94 (51%), Gaps = 3/94 (3%)

Query: 235 KQEKRNQDRLRRREEREREERLSRRSGSRTRDRRRSRSRDRRRR---RSRSTSRERRKLS 291
           K+E+R +++ +R  E+ER+    ++   + + R R + R+R+R+   + R   RE+ +  
Sbjct: 37  KKERREREKRKREREKERKRERGKKEKKKRKKRERGKERERKRKEREKQRKERREKERRK 96

Query: 292 RSRSRDRHRRHRSRSRSHSRGHRRASRDRSAKYK 325
           R + + +  R +   R   +   R  R+R  K +
Sbjct: 97  RKKEKKKRERKQRGRRERKKKKERKERERENKQR 130



 Score = 43.5 bits (101), Expect = 3e-04
 Identities = 20/80 (25%), Positives = 39/80 (48%), Gaps = 1/80 (1%)

Query: 246 RREEREREERLSRRSGSRTRDRRRSRSRDRRRRRSRSTSRERRKLSRSRSRDRHRRHRSR 305
           +RE   ++ER  R    R R++ R R R ++ ++ R   RER K    + ++R ++ + R
Sbjct: 31  QRESERKKERREREKRKREREKERKRERGKKEKKKRK-KRERGKERERKRKEREKQRKER 89

Query: 306 SRSHSRGHRRASRDRSAKYK 325
                R  ++  + R  K +
Sbjct: 90  REKERRKRKKEKKKRERKQR 109



 Score = 41.2 bits (95), Expect = 0.001
 Identities = 48/202 (23%), Positives = 81/202 (40%), Gaps = 7/202 (3%)

Query: 96  ECDRRTELAK--KRLAETQEEISAEVSAKAEKVHELNEEIGKLLAKAEQLGAEGNVDESQ 153
           E +R+ E  +  KR  E ++E   E   K EK      E GK   + E+   E      +
Sbjct: 33  ESERKKERREREKRKREREKERKRE-RGKKEKKKRKKRERGK---ERERKRKEREKQRKE 88

Query: 154 KILMEVEKVRAKKKEAEEEYRNSMPASSFQQQKLRVCEVCSAYLGLHDNDRRLADHFGGK 213
           +   E  K + +KK+ E + R        +++K R  E            R+       K
Sbjct: 89  RREKERRKRKKEKKKRERKQRGRRERKKKKERKERERENKQRRERKRKKRRKKKRRKERK 148

Query: 214 LHLGFIQIREKLDQLRKTVAEKQEKRNQ-DRLRRREEREREERLSRRSGSRTRDRRRSRS 272
                 +   K  + +K   EK+ +RN+ +R + RE +ER ER   R   R + + R + 
Sbjct: 149 REKERGKRERKRKKRKKEEREKKRERNRKERKKERERKERRERKKERKKERRKKKERKKD 208

Query: 273 RDRRRRRSRSTSRERRKLSRSR 294
           R   R+      R  R+ + +R
Sbjct: 209 RKTDRQTDSQVFRPLRESAFNR 230


>gi|21040326 SON DNA-binding protein isoform F [Homo sapiens]
          Length = 2426

 Score = 64.7 bits (156), Expect = 1e-10
 Identities = 38/94 (40%), Positives = 53/94 (56%), Gaps = 2/94 (2%)

Query: 230  KTVAEKQEKRNQDRLRRREEREREERLSRRSGSRTRDRR--RSRSRDRRRRRSRSTSRER 287
            K+   +   R++ R RRR  R R +   RRS S+ + +R  + RS+ R R+R RS+SR+ 
Sbjct: 1855 KSHRSQTRSRSRSRRRRRSSRSRSKSRGRRSVSKEKRKRSPKHRSKSRERKRKRSSSRDN 1914

Query: 288  RKLSRSRSRDRHRRHRSRSRSHSRGHRRASRDRS 321
            RK  R+RSR   RR RS + S  R  R   R RS
Sbjct: 1915 RKTVRARSRTPSRRSRSHTPSRRRRSRSVGRRRS 1948



 Score = 64.3 bits (155), Expect = 1e-10
 Identities = 43/99 (43%), Positives = 60/99 (60%), Gaps = 9/99 (9%)

Query: 235  KQEKRNQDRLRRREEREREERLSRRS----GSRTRDRRR-SRSRDRRRRRSRSTSRERRK 289
            ++ K+N++R +  +E++R+  L  RS     S  + R+R S SR R R+RS S S+  R 
Sbjct: 1801 EKSKKNKNRDKGEKEKKRDSSLRSRSKRSKSSEHKSRKRTSESRSRARKRS-SKSKSHRS 1859

Query: 290  LSRSRSRDRHRRHRSRSRSHSRGHRRAS---RDRSAKYK 325
             +RSRSR R RR  SRSRS SRG R  S   R RS K++
Sbjct: 1860 QTRSRSRSRRRRRSSRSRSKSRGRRSVSKEKRKRSPKHR 1898



 Score = 63.2 bits (152), Expect = 3e-10
 Identities = 42/115 (36%), Positives = 62/115 (53%), Gaps = 9/115 (7%)

Query: 218  FIQIREKLDQLRKTV----AEKQEKRNQDRLRRREEREREERLSRRSGSRTRDRRRSRS- 272
            F+++++  ++ +K       EK++KR+     R +  +  E  SR+  S +R R R RS 
Sbjct: 1793 FVKVKDTHEKSKKNKNRDKGEKEKKRDSSLRSRSKRSKSSEHKSRKRTSESRSRARKRSS 1852

Query: 273  ---RDRRRRRSRSTSRERRKLSRSRSRDRHRRHRSR-SRSHSRGHRRASRDRSAK 323
                 R + RSRS SR RR+ SRSRS+ R RR  S+  R  S  HR  SR+R  K
Sbjct: 1853 KSKSHRSQTRSRSRSRRRRRSSRSRSKSRGRRSVSKEKRKRSPKHRSKSRERKRK 1907



 Score = 59.3 bits (142), Expect = 4e-09
 Identities = 42/108 (38%), Positives = 58/108 (53%), Gaps = 9/108 (8%)

Query: 222  REKLDQLRKTVAEKQEKRNQDRLRRREEREREERLSRRSGSRTRDRRRSRSRDRRRR--- 278
            +++   LR      +   ++ R R  E R R  + S +S S  R + RSRSR RRRR   
Sbjct: 1816 KKRDSSLRSRSKRSKSSEHKSRKRTSESRSRARKRSSKSKSH-RSQTRSRSRSRRRRRSS 1874

Query: 279  RSRSTSRERRKLSRSRSR--DRHR---RHRSRSRSHSRGHRRASRDRS 321
            RSRS SR RR +S+ + +   +HR   R R R RS SR +R+  R RS
Sbjct: 1875 RSRSKSRGRRSVSKEKRKRSPKHRSKSRERKRKRSSSRDNRKTVRARS 1922



 Score = 57.4 bits (137), Expect = 2e-08
 Identities = 48/113 (42%), Positives = 60/113 (53%), Gaps = 12/113 (10%)

Query: 222  REKLDQLRKTVAEKQEKRNQDRLRRREEREREERLSRRSGSRTRD-RRRSRSRDRRR--- 277
            R++  + R    E++ KR+  R  R+  R R    SRRS S T   RRRSRS  RRR   
Sbjct: 1891 RKRSPKHRSKSRERKRKRSSSRDNRKTVRARSRTPSRRSRSHTPSRRRRSRSVGRRRSFS 1950

Query: 278  ----RRSRSTSRERRKLSRSRSRDRHRRHRS---RSRSHSRGHRRASRDRSAK 323
                RRSR+ SR  R  SR RSR   RR R+   RSR+ SR  R  SR R ++
Sbjct: 1951 ISPSRRSRTPSRRSRTPSR-RSRTPSRRSRTPSRRSRTPSRRSRTPSRRRRSR 2002



 Score = 42.7 bits (99), Expect = 4e-04
 Identities = 34/87 (39%), Positives = 44/87 (50%), Gaps = 9/87 (10%)

Query: 236  QEKRNQDRLRRREEREREERLSRRSGSRTRDRRRS-RSRDR---RRRRSRSTSRERRKLS 291
            +EKR +    R + RER     +R  S +RD R++ R+R R   RR RS + SR RR  S
Sbjct: 1888 KEKRKRSPKHRSKSRER-----KRKRSSSRDNRKTVRARSRTPSRRSRSHTPSRRRRSRS 1942

Query: 292  RSRSRDRHRRHRSRSRSHSRGHRRASR 318
              R R        RSR+ SR  R  SR
Sbjct: 1943 VGRRRSFSISPSRRSRTPSRRSRTPSR 1969



 Score = 40.8 bits (94), Expect = 0.002
 Identities = 42/117 (35%), Positives = 48/117 (41%), Gaps = 9/117 (7%)

Query: 204  RRLADHFGGKLHLGFIQIREKLDQLRKTVAEKQEKRNQDRLRRREEREREERLSRRSGSR 263
            RR +   G +        R      R++    +  R   R R R    R    SRRS  R
Sbjct: 1937 RRRSRSVGRRRSFSISPSRRSRTPSRRSRTPSRRSRTPSR-RSRTPSRRSRTPSRRS--R 1993

Query: 264  TRDRRRSRSRDRRRRRSRSTS-----RERRKLSRSRSRDRHRRHRSRSRSHSRGHRR 315
            T  RRR RSR   RRRS S S     R R  L R  SR   RR RSRS    R  +R
Sbjct: 1994 TPSRRR-RSRSVVRRRSFSISPVRLRRSRTPLRRRFSRSPIRRKRSRSSERGRSPKR 2049



 Score = 40.4 bits (93), Expect = 0.002
 Identities = 39/104 (37%), Positives = 49/104 (47%), Gaps = 10/104 (9%)

Query: 229  RKTVAEKQEKRNQDRLRRREEREREERL-SRRSGSRTRDRRRSRSRDR---RRRRSRSTS 284
            R++ +    +R++   RR     R  R  SRRS + +R  R    R R   RRRRSRS  
Sbjct: 1946 RRSFSISPSRRSRTPSRRSRTPSRRSRTPSRRSRTPSRRSRTPSRRSRTPSRRRRSRSVV 2005

Query: 285  RERRKLSRS-----RSRDRHRRHRSRSRSHSRGHRRASRDRSAK 323
            R RR  S S     RSR   RR  SRS    +  R + R RS K
Sbjct: 2006 R-RRSFSISPVRLRRSRTPLRRRFSRSPIRRKRSRSSERGRSPK 2048


>gi|21040314 SON DNA-binding protein isoform B [Homo sapiens]
          Length = 2303

 Score = 64.7 bits (156), Expect = 1e-10
 Identities = 38/94 (40%), Positives = 53/94 (56%), Gaps = 2/94 (2%)

Query: 230  KTVAEKQEKRNQDRLRRREEREREERLSRRSGSRTRDRR--RSRSRDRRRRRSRSTSRER 287
            K+   +   R++ R RRR  R R +   RRS S+ + +R  + RS+ R R+R RS+SR+ 
Sbjct: 1855 KSHRSQTRSRSRSRRRRRSSRSRSKSRGRRSVSKEKRKRSPKHRSKSRERKRKRSSSRDN 1914

Query: 288  RKLSRSRSRDRHRRHRSRSRSHSRGHRRASRDRS 321
            RK  R+RSR   RR RS + S  R  R   R RS
Sbjct: 1915 RKTVRARSRTPSRRSRSHTPSRRRRSRSVGRRRS 1948



 Score = 64.3 bits (155), Expect = 1e-10
 Identities = 43/99 (43%), Positives = 60/99 (60%), Gaps = 9/99 (9%)

Query: 235  KQEKRNQDRLRRREEREREERLSRRS----GSRTRDRRR-SRSRDRRRRRSRSTSRERRK 289
            ++ K+N++R +  +E++R+  L  RS     S  + R+R S SR R R+RS S S+  R 
Sbjct: 1801 EKSKKNKNRDKGEKEKKRDSSLRSRSKRSKSSEHKSRKRTSESRSRARKRS-SKSKSHRS 1859

Query: 290  LSRSRSRDRHRRHRSRSRSHSRGHRRAS---RDRSAKYK 325
             +RSRSR R RR  SRSRS SRG R  S   R RS K++
Sbjct: 1860 QTRSRSRSRRRRRSSRSRSKSRGRRSVSKEKRKRSPKHR 1898



 Score = 63.2 bits (152), Expect = 3e-10
 Identities = 42/115 (36%), Positives = 62/115 (53%), Gaps = 9/115 (7%)

Query: 218  FIQIREKLDQLRKTV----AEKQEKRNQDRLRRREEREREERLSRRSGSRTRDRRRSRS- 272
            F+++++  ++ +K       EK++KR+     R +  +  E  SR+  S +R R R RS 
Sbjct: 1793 FVKVKDTHEKSKKNKNRDKGEKEKKRDSSLRSRSKRSKSSEHKSRKRTSESRSRARKRSS 1852

Query: 273  ---RDRRRRRSRSTSRERRKLSRSRSRDRHRRHRSR-SRSHSRGHRRASRDRSAK 323
                 R + RSRS SR RR+ SRSRS+ R RR  S+  R  S  HR  SR+R  K
Sbjct: 1853 KSKSHRSQTRSRSRSRRRRRSSRSRSKSRGRRSVSKEKRKRSPKHRSKSRERKRK 1907



 Score = 59.3 bits (142), Expect = 4e-09
 Identities = 42/108 (38%), Positives = 58/108 (53%), Gaps = 9/108 (8%)

Query: 222  REKLDQLRKTVAEKQEKRNQDRLRRREEREREERLSRRSGSRTRDRRRSRSRDRRRR--- 278
            +++   LR      +   ++ R R  E R R  + S +S S  R + RSRSR RRRR   
Sbjct: 1816 KKRDSSLRSRSKRSKSSEHKSRKRTSESRSRARKRSSKSKSH-RSQTRSRSRSRRRRRSS 1874

Query: 279  RSRSTSRERRKLSRSRSR--DRHR---RHRSRSRSHSRGHRRASRDRS 321
            RSRS SR RR +S+ + +   +HR   R R R RS SR +R+  R RS
Sbjct: 1875 RSRSKSRGRRSVSKEKRKRSPKHRSKSRERKRKRSSSRDNRKTVRARS 1922



 Score = 57.4 bits (137), Expect = 2e-08
 Identities = 48/113 (42%), Positives = 60/113 (53%), Gaps = 12/113 (10%)

Query: 222  REKLDQLRKTVAEKQEKRNQDRLRRREEREREERLSRRSGSRTRD-RRRSRSRDRRR--- 277
            R++  + R    E++ KR+  R  R+  R R    SRRS S T   RRRSRS  RRR   
Sbjct: 1891 RKRSPKHRSKSRERKRKRSSSRDNRKTVRARSRTPSRRSRSHTPSRRRRSRSVGRRRSFS 1950

Query: 278  ----RRSRSTSRERRKLSRSRSRDRHRRHRS---RSRSHSRGHRRASRDRSAK 323
                RRSR+ SR  R  SR RSR   RR R+   RSR+ SR  R  SR R ++
Sbjct: 1951 ISPSRRSRTPSRRSRTPSR-RSRTPSRRSRTPSRRSRTPSRRSRTPSRRRRSR 2002



 Score = 42.7 bits (99), Expect = 4e-04
 Identities = 34/87 (39%), Positives = 44/87 (50%), Gaps = 9/87 (10%)

Query: 236  QEKRNQDRLRRREEREREERLSRRSGSRTRDRRRS-RSRDR---RRRRSRSTSRERRKLS 291
            +EKR +    R + RER     +R  S +RD R++ R+R R   RR RS + SR RR  S
Sbjct: 1888 KEKRKRSPKHRSKSRER-----KRKRSSSRDNRKTVRARSRTPSRRSRSHTPSRRRRSRS 1942

Query: 292  RSRSRDRHRRHRSRSRSHSRGHRRASR 318
              R R        RSR+ SR  R  SR
Sbjct: 1943 VGRRRSFSISPSRRSRTPSRRSRTPSR 1969



 Score = 40.8 bits (94), Expect = 0.002
 Identities = 42/117 (35%), Positives = 48/117 (41%), Gaps = 9/117 (7%)

Query: 204  RRLADHFGGKLHLGFIQIREKLDQLRKTVAEKQEKRNQDRLRRREEREREERLSRRSGSR 263
            RR +   G +        R      R++    +  R   R R R    R    SRRS  R
Sbjct: 1937 RRRSRSVGRRRSFSISPSRRSRTPSRRSRTPSRRSRTPSR-RSRTPSRRSRTPSRRS--R 1993

Query: 264  TRDRRRSRSRDRRRRRSRSTS-----RERRKLSRSRSRDRHRRHRSRSRSHSRGHRR 315
            T  RRR RSR   RRRS S S     R R  L R  SR   RR RSRS    R  +R
Sbjct: 1994 TPSRRR-RSRSVVRRRSFSISPVRLRRSRTPLRRRFSRSPIRRKRSRSSERGRSPKR 2049



 Score = 40.4 bits (93), Expect = 0.002
 Identities = 39/104 (37%), Positives = 49/104 (47%), Gaps = 10/104 (9%)

Query: 229  RKTVAEKQEKRNQDRLRRREEREREERL-SRRSGSRTRDRRRSRSRDR---RRRRSRSTS 284
            R++ +    +R++   RR     R  R  SRRS + +R  R    R R   RRRRSRS  
Sbjct: 1946 RRSFSISPSRRSRTPSRRSRTPSRRSRTPSRRSRTPSRRSRTPSRRSRTPSRRRRSRSVV 2005

Query: 285  RERRKLSRS-----RSRDRHRRHRSRSRSHSRGHRRASRDRSAK 323
            R RR  S S     RSR   RR  SRS    +  R + R RS K
Sbjct: 2006 R-RRSFSISPVRLRRSRTPLRRRFSRSPIRRKRSRSSERGRSPK 2048


>gi|239747134 PREDICTED: hypothetical protein XP_002343921 [Homo
           sapiens]
          Length = 600

 Score = 63.9 bits (154), Expect = 2e-10
 Identities = 60/231 (25%), Positives = 101/231 (43%), Gaps = 17/231 (7%)

Query: 96  ECDRRTELAKKRLAETQEEISAEVSAKAEKVHELNEEIGKLLAKAEQLGAEGNVDESQKI 155
           E +R  E  + R  + Q E   +  A+ E+  + + E  +   +  Q   E   +  ++ 
Sbjct: 130 ETEREGERGRDRQTDGQRERERQRDAEKERERQTDRERQRQTERNRQKEREREKNRQERR 189

Query: 156 LMEVEKVRAKKKEAEEEYRNSMPASSFQQQKLRVCEVCSAYLGLHDNDRRLADHFGGKLH 215
               E+ R ++KE + E R+S      ++++    E         + DR+       +  
Sbjct: 190 ----ERERQREKENKTEDRHSERGRERERERETETETERKRQTDRERDRQRKTEREREKQ 245

Query: 216 LGFIQIREKLDQLRKTVAEKQEKRNQDRLRRREEREREERLSRRSGSRTRDRRRSRSRDR 275
                 RE+  + R+T  +K+ +R +DR R R+ R++E     R   R R RR  R R+ 
Sbjct: 246 AE----RERASE-RETERDKERERERDRDRDRDRRQKERE---RQTDRKRQRRTERDRET 297

Query: 276 RRRRSRSTSRERRKLSRSRSRDRHR---RHRSRSRSHSRGHRRASRDRSAK 323
            R+R R   RER +  R+R R+R R   R R R R   R  R   R+R  K
Sbjct: 298 ERKRERQRERERER-ERNRKRERERERERERERQRETER-DREKERERKRK 346



 Score = 62.8 bits (151), Expect = 4e-10
 Identities = 54/224 (24%), Positives = 89/224 (39%), Gaps = 9/224 (4%)

Query: 98  DRRTELAKKRLAETQEEISAEVSAKAEKVHELNEEIGKLLAKAEQLGAEGNVDESQKILM 157
           DR  E  + R  E + +   E   + EK     +E  +   +  + G +   D  +    
Sbjct: 92  DRHRERQRDREKERERQTDRERDRQREKERNRQKERERETEREGERGRDRQTDGQR---- 147

Query: 158 EVEKVRAKKKEAEEEY-RNSMPASSFQQQKLRVCEVCSAYLGLHDNDRRLADHFGGKLHL 216
           E E+ R  +KE E +  R     +   +QK R  E         +  R   +    K   
Sbjct: 148 ERERQRDAEKERERQTDRERQRQTERNRQKEREREKNRQERRERERQREKEN----KTED 203

Query: 217 GFIQIREKLDQLRKTVAEKQEKRNQDRLRRREEREREERLSRRSGSRTRDRRRSRSRDRR 276
              +   + ++ R+T  E + KR  DR R R+ +   ER  +    R  +R   R ++R 
Sbjct: 204 RHSERGRERERERETETETERKRQTDRERDRQRKTEREREKQAERERASERETERDKERE 263

Query: 277 RRRSRSTSRERRKLSRSRSRDRHRRHRSRSRSHSRGHRRASRDR 320
           R R R   R+RR+  R R  DR R+ R+     +   R   R+R
Sbjct: 264 RERDRDRDRDRRQKERERQTDRKRQRRTERDRETERKRERQRER 307



 Score = 59.3 bits (142), Expect = 4e-09
 Identities = 38/95 (40%), Positives = 53/95 (55%), Gaps = 6/95 (6%)

Query: 229 RKTVAEKQEKRNQDRLRRRE-ERERE-ERLSRRSGSRTRDRRRSRSRDRRRRRSRSTSRE 286
           R+   E++ +RN+ R R RE ERERE +R + R   + R+R+R R  +  R R+R T RE
Sbjct: 303 RQRERERERERNRKRERERERERERERQRETERDREKERERKRKRQTEMDRERNRQTGRE 362

Query: 287 -RRKLSRSRSRDRHRRHRSRSRSHSRGHRRASRDR 320
            RR+  R R R+   R R R  +  R  R   RDR
Sbjct: 363 GRRQAERERERE---RERDRQSAREREERERDRDR 394



 Score = 58.9 bits (141), Expect = 6e-09
 Identities = 38/104 (36%), Positives = 52/104 (50%), Gaps = 14/104 (13%)

Query: 234 EKQEKRNQDRLRRREERERE-------ERLSRRSGSRTRDRRRSRSRDRRRRRSRSTSRE 286
           +++  R ++R RRRE+R+ E       ER   +   R RDR R R RDR + R R T RE
Sbjct: 53  DRERNRQKERERRREKRQTERETDRKRERRREKDRHRKRDRHRERQRDREKERERQTDRE 112

Query: 287 R---RKLSRSRSRDRHRR-HRSRSRSHSR---GHRRASRDRSAK 323
           R   R+  R+R ++R R   R   R   R   G R   R R A+
Sbjct: 113 RDRQREKERNRQKERERETEREGERGRDRQTDGQRERERQRDAE 156



 Score = 57.4 bits (137), Expect = 2e-08
 Identities = 34/103 (33%), Positives = 54/103 (52%), Gaps = 5/103 (4%)

Query: 222 REKLDQLRKTVAEKQEKRNQDRLRRRE---EREREERLSR-RSGSRTRDRRRSRSRDRRR 277
           REK    R+T  +++ +R +DR R+R+   ER+R+    R R   R RDR+R + R+R++
Sbjct: 66  REKRQTERETDRKRERRREKDRHRKRDRHRERQRDREKERERQTDRERDRQREKERNRQK 125

Query: 278 RRSRSTSRERRKLSRSRSRDRHRRHRSRSRSHSRGHRRASRDR 320
            R R T RE  +  R R  D  R    +  +     R+  R+R
Sbjct: 126 ERERETEREGER-GRDRQTDGQRERERQRDAEKERERQTDRER 167



 Score = 57.0 bits (136), Expect = 2e-08
 Identities = 41/112 (36%), Positives = 60/112 (53%), Gaps = 15/112 (13%)

Query: 222 REKLDQLRKTVAEKQEKRNQDRLRRREEREREERLSRRSGSRTRDRR------RSRSRDR 275
           REK ++ R+T  E+  +R ++R  R++ERERE   + R G R RDR+      R R RD 
Sbjct: 101 REK-ERERQTDRERDRQREKER-NRQKERERE---TEREGERGRDRQTDGQRERERQRDA 155

Query: 276 RRRRSRSTSRER-RKLSRSRSRDRHR---RHRSRSRSHSRGHRRASRDRSAK 323
            + R R T RER R+  R+R ++R R   R   R R   R     + DR ++
Sbjct: 156 EKERERQTDRERQRQTERNRQKEREREKNRQERRERERQREKENKTEDRHSE 207



 Score = 56.6 bits (135), Expect = 3e-08
 Identities = 55/228 (24%), Positives = 98/228 (42%), Gaps = 30/228 (13%)

Query: 99  RRTELAKKRLAETQEEISAEVSAKAEKVHELNEEIGKLLAKAEQLGAEGNVDESQKILME 158
           R+TE  +++ AE +     E     E+  E + +  +   + E+   E   D  ++   E
Sbjct: 236 RKTEREREKQAERERASERETERDKERERERDRDRDRDRRQKER---ERQTDRKRQRRTE 292

Query: 159 VEKVRAKKKEAEEEYRNSMPASSFQQQKLRVCEVCSAYLGLHDNDRRLADHFGGKLHLGF 218
            ++   +K+E + E R      + ++++ R  E         + DR              
Sbjct: 293 RDRETERKRERQRE-RERERERNRKRERERERERERERQRETERDRE------------- 338

Query: 219 IQIREKLDQLRKTVAEKQEKRNQDRLRRRE---EREREERLSRRSGSRTRDRRRSRSRDR 275
            + RE+  + R+T  +++  R   R  RR+   ERERE    R+S     +R R R RDR
Sbjct: 339 -KERER-KRKRQTEMDRERNRQTGREGRRQAERERERERERDRQSAREREERERDRDRDR 396

Query: 276 RRRRSRSTSRER---RKLSRSRSRDRHR-----RHRSRSRSHSRGHRR 315
           ++ R R T ++R   R+  + R R++ R     R R R R   +G  R
Sbjct: 397 QKERERQTEKDRDGQRETEKQREREKDRESERGRERGREREKQKGRER 444



 Score = 55.5 bits (132), Expect = 6e-08
 Identities = 52/225 (23%), Positives = 90/225 (40%), Gaps = 28/225 (12%)

Query: 98  DRRTELAKKRLAET---------QEEISAEVSAKAEKVHELNEEIGKLLAKAEQLGAEGN 148
           +R TE  K+R  E          Q+E   +   K ++  E + E  +   +  +   E  
Sbjct: 253 ERETERDKERERERDRDRDRDRRQKERERQTDRKRQRRTERDRETERKRERQRERERERE 312

Query: 149 VDESQKILMEVEKVRAKKKEAEEEYRNSMPASSFQQQKLRVCEVCSAYLGLHDNDRRLAD 208
            +  ++   E E+ R +++E E +          +Q ++               DR    
Sbjct: 313 RNRKRERERERERERERQRETERDREKERERKRKRQTEM---------------DRERNR 357

Query: 209 HFGGKLHLGFIQIREKLDQLRKTVAEKQEKRNQDRLRRREEREREERLSRRSGSRTRDRR 268
             G +      + RE+  +  +  A ++E+R +DR R R++    +    R G R  +++
Sbjct: 358 QTGREGRRQAERERERERERDRQSAREREERERDRDRDRQKERERQTEKDRDGQRETEKQ 417

Query: 269 RSRSRDRRRRRSRSTSRERRKLSRSRSRDRHR---RHRSRSRSHS 310
           R R +DR   R R   RER K  + R RDR R   R   R R  S
Sbjct: 418 REREKDRESERGRERGREREK-QKGRERDRERQTDRQAGRQRKRS 461



 Score = 55.1 bits (131), Expect = 8e-08
 Identities = 35/115 (30%), Positives = 55/115 (47%), Gaps = 14/115 (12%)

Query: 220 QIREKLDQLRKTVAEKQEKRNQDRLRRRE-ERERE---ERLSRRSGSRTRDRRRS----- 270
           Q   + ++ R    E++ +R ++R R+RE ER+RE   ER  +R     R+R R      
Sbjct: 304 QRERERERERNRKRERERERERERERQRETERDREKERERKRKRQTEMDRERNRQTGREG 363

Query: 271 -----RSRDRRRRRSRSTSRERRKLSRSRSRDRHRRHRSRSRSHSRGHRRASRDR 320
                R R+R R R R ++RER +  R R RDR +    ++     G R   + R
Sbjct: 364 RRQAERERERERERDRQSAREREERERDRDRDRQKERERQTEKDRDGQRETEKQR 418



 Score = 54.3 bits (129), Expect = 1e-07
 Identities = 34/112 (30%), Positives = 49/112 (43%), Gaps = 9/112 (8%)

Query: 222 REKLDQLRKTVAEKQEKRNQDRLRRREEREREERLSRRSGSRTRDRRRSRSRDRRRRRSR 281
           R++  +  +    ++EK  Q+R  R  +RE+E +   R   R R+R R R  +    R R
Sbjct: 167 RQRQTERNRQKEREREKNRQERRERERQREKENKTEDRHSERGRERERERETETETERKR 226

Query: 282 STSRER---RKLSRSRSRDRHR-----RHRSRSRSHSRGHRRASRDRSAKYK 325
            T RER   RK  R R +   R     R   R +   R  R   RDR  + K
Sbjct: 227 QTDRERDRQRKTEREREKQAERERASERETERDKERER-ERDRDRDRDRRQK 277



 Score = 53.5 bits (127), Expect = 2e-07
 Identities = 32/98 (32%), Positives = 50/98 (51%), Gaps = 7/98 (7%)

Query: 229 RKTVAEKQEKRNQDRLRRREEREREERLSRRSGSRTRDRRRSRSRDRRRRRSRSTSRERR 288
           R+ + +  +  + D   R  ++ERE R  +R   R  DR+R R R++ R R R   RER+
Sbjct: 39  RRGLGQAHKDADGDDRERNRQKERERRREKRQTERETDRKRERRREKDRHRKRDRHRERQ 98

Query: 289 KLSRSRSRDRHR---RHRSRSRSHSRGHRRASRDRSAK 323
              R R ++R R   R R R R   R +R+  R+R  +
Sbjct: 99  ---RDREKERERQTDRERDRQREKER-NRQKERERETE 132



 Score = 47.8 bits (112), Expect = 1e-05
 Identities = 32/105 (30%), Positives = 54/105 (51%), Gaps = 5/105 (4%)

Query: 222 REKLDQLRKTVAEKQEKRNQDRLRRREEREREERLSRRSGSRTRDRR--RSRSRDRRRRR 279
           REK ++ R+   E++ +R  +R R R+   + ER  +R   + R+R+  R R R   R R
Sbjct: 117 REK-ERNRQKERERETEREGERGRDRQTDGQRERERQRDAEKERERQTDRERQRQTERNR 175

Query: 280 SRSTSRER-RKLSRSRSRDRHRRHRSRSRSHSRGHRRASRDRSAK 323
            +   RE+ R+  R R R R + +++  R   RG  R  R+R  +
Sbjct: 176 QKEREREKNRQERRERERQREKENKTEDRHSERGRER-ERERETE 219



 Score = 46.6 bits (109), Expect = 3e-05
 Identities = 30/100 (30%), Positives = 49/100 (49%), Gaps = 8/100 (8%)

Query: 224 KLDQLRKTVAEKQEKRNQDRLRRREEREREERLSRRSGSRTRDRRRSRSRDRR------R 277
           K D+ R+   +++++R +   R R+ +  +ER  ++   R  +R   R RDR+      R
Sbjct: 90  KRDRHRERQRDREKERERQTDRERDRQREKERNRQKERERETEREGERGRDRQTDGQRER 149

Query: 278 RRSRSTSRER-RKLSRSRSRDRHR-RHRSRSRSHSRGHRR 315
            R R   +ER R+  R R R   R R + R R  +R  RR
Sbjct: 150 ERQRDAEKERERQTDRERQRQTERNRQKEREREKNRQERR 189



 Score = 42.0 bits (97), Expect = 7e-04
 Identities = 42/195 (21%), Positives = 72/195 (36%), Gaps = 49/195 (25%)

Query: 96  ECDRRTELAKKRLAETQEEISAEVSAKAEKVHELNEEIGKLLAKAEQLGAEGNVDESQKI 155
           E +R  E  ++R  ET+ +   E   K ++  E++ E      +  Q G EG     ++ 
Sbjct: 318 ERERERERERERQRETERDREKERERKRKRQTEMDRE------RNRQTGREGRRQAERER 371

Query: 156 LMEVEKVRAKKKEAEEEYRNSMPASSFQQQKLRVCEVCSAYLGLHDNDRRLADHFGGKLH 215
             E E+ R   +E EE  R+                         D DR+          
Sbjct: 372 ERERERDRQSAREREERERD------------------------RDRDRQK--------- 398

Query: 216 LGFIQIREKLDQLRKTVAEKQEKRNQDRLRRREEREREERLSRRSGSRTRDRRRSRSRDR 275
                     ++ R+T  ++  +R  ++ R RE+    ER   R   R + + R R R+R
Sbjct: 399 ----------ERERQTEKDRDGQRETEKQREREKDRESERGRERGREREKQKGRERDRER 448

Query: 276 RRRRSRSTSRERRKL 290
           +  R     R+R  L
Sbjct: 449 QTDRQAGRQRKRSTL 463



 Score = 40.0 bits (92), Expect = 0.003
 Identities = 27/74 (36%), Positives = 34/74 (45%), Gaps = 12/74 (16%)

Query: 258 RRSGSRTRDRRRSRS----------RDRRRRRSRSTSRERRKLSRSRSRDR-HRRHRSRS 306
           RR GS+   RRR             R+R R++ R   RE+R+  R   R R  RR + R 
Sbjct: 29  RRPGSQESPRRRGLGQAHKDADGDDRERNRQKERERRREKRQTERETDRKRERRREKDRH 88

Query: 307 RSHSRGHRRASRDR 320
           R   R HR   RDR
Sbjct: 89  RKRDR-HRERQRDR 101


>gi|116008442 zinc finger CCCH-type containing 13 [Homo sapiens]
          Length = 1564

 Score = 63.9 bits (154), Expect = 2e-10
 Identities = 75/307 (24%), Positives = 125/307 (40%), Gaps = 25/307 (8%)

Query: 19  RDGDETRQRVKFTDDRVCKS--HLLDCCPHDILAGTRMDLGECTKIHDLALRADYEIASK 76
           RD  +TR R +  D R  +    + D       +    D       HD   R   +   K
Sbjct: 459 RDARDTRDRRELRDSRDMRDSREMRDYSRDTKESRDPRDSRSTRDAHDYRDREGRDTHRK 518

Query: 77  ERDLFFELDAMDHLESFIAECDRRTELAKKRLAETQEEISAEVSAKAE-KVHELNEEIGK 135
           E D + E ++  +  + + E   RTE+  +   E++ EI  +   ++  +V EL E+ G 
Sbjct: 519 E-DTYPE-ESRSYGRNHLREESSRTEIRNESRNESRSEIRNDRMGRSRGRVPELPEK-GS 575

Query: 136 LLAKAEQLGAEGNVDESQKILMEVEKVRAKKKEAEEEYRNSMPASSFQQQKLRVCEVCSA 195
             ++  Q+ +  +                + +  E + R+    SSF+++          
Sbjct: 576 RGSRGSQIDSHSSNSNYHDSWETRSSYPERDRYPERDNRDQARDSSFERR---------- 625

Query: 196 YLGLHDNDRRLADHFGGKLHLGFIQIREKLDQLRKTVAEKQEKRNQDRLRRREEREREER 255
               H    R  +    +     I+ + + D+L +   E++E+R  DR+  R +    ER
Sbjct: 626 ----HGERDRRDNRERDQRPSSPIRHQGRNDELERD--ERREERRVDRVDDRRDERARER 679

Query: 256 LSRRSGSRTRDRRRSRSRDRRRRRSRSTSRERRKLSRSRSRDRHR-RHRSRSRSHSR-GH 313
              R   R R+R R R RDR R + R   RER +  R R R++ R R R R R H R   
Sbjct: 680 DRERERDRERERERERERDREREKERELERERAR-EREREREKERDRERDRDRDHDRERE 738

Query: 314 RRASRDR 320
           R   RDR
Sbjct: 739 RERERDR 745



 Score = 61.2 bits (147), Expect = 1e-09
 Identities = 36/94 (38%), Positives = 46/94 (48%), Gaps = 2/94 (2%)

Query: 234 EKQEKRNQDRLRRREEREREERLSRRSGSRTRDRRRSRSRDRRRRRSRSTSRERRKLSRS 293
           EK+ +  ++R R RE    +ER   R   R  DR R R R+R R + R   RE R+  R 
Sbjct: 702 EKERELERERAREREREREKERDRERDRDRDHDRERERERERDREKEREREREERERERE 761

Query: 294 RSRDRHR-RHRSRSRSHSRG-HRRASRDRSAKYK 325
           R R+R R R R R R+  R   R   RD   K K
Sbjct: 762 RERERERERERERERARERDKERERQRDWEDKDK 795



 Score = 60.8 bits (146), Expect = 2e-09
 Identities = 39/101 (38%), Positives = 50/101 (49%), Gaps = 11/101 (10%)

Query: 226 DQLRKTVAEKQEKRNQDRLRRREE---------RERE-ERLSRRSGSRTRDRRRSRSRDR 275
           D+ R+   E++ +R ++R R RE+         RERE ER   R   R RDR   R R+R
Sbjct: 680 DRERERDRERERERERERDREREKERELERERAREREREREKERDRERDRDRDHDRERER 739

Query: 276 RRRRSRSTSRERRKLSRSRSRDRHR-RHRSRSRSHSRGHRR 315
            R R R   RER +  R R R+R R R R R R   R   R
Sbjct: 740 ERERDREKEREREREERERERERERERERERERERERARER 780



 Score = 58.5 bits (140), Expect = 8e-09
 Identities = 33/89 (37%), Positives = 44/89 (49%), Gaps = 2/89 (2%)

Query: 234 EKQEKRNQDRLRRREEREREERLSRRSGSRTRDRRRSRSRDRRRRRSRSTSRER-RKLSR 292
           E++ +R +DR R +E     ER   R   R ++R R R RDR   R R   RER R+  R
Sbjct: 690 ERERERERDREREKERELERERAREREREREKERDRERDRDRDHDRERERERERDREKER 749

Query: 293 SRSRDRHRRHRSRSRSHSRGHRRASRDRS 321
            R R+   R R R R   R  R   R+R+
Sbjct: 750 EREREERERERERERERER-ERERERERA 777



 Score = 58.2 bits (139), Expect = 1e-08
 Identities = 34/98 (34%), Positives = 49/98 (50%), Gaps = 2/98 (2%)

Query: 229 RKTVAEKQEKRNQDRLRRREEREREERLSRRSGSRTRDRRRSRSRDRRRRRSRSTSRERR 288
           R+   E++++R  +R R RE     E+   R   R RD  R R R+R R R +   RER 
Sbjct: 695 RERDREREKERELERERAREREREREKERDRERDRDRDHDRERERERERDREKERERERE 754

Query: 289 KLSRSRSRDRHR-RHRSRSRSHSRGHRRASRDRSAKYK 325
           +  R R R+R R R R R R  +R  R   R+R   ++
Sbjct: 755 ERERERERERERERERERERERAR-ERDKERERQRDWE 791



 Score = 57.0 bits (136), Expect = 2e-08
 Identities = 37/96 (38%), Positives = 50/96 (52%), Gaps = 4/96 (4%)

Query: 229 RKTVAEKQEKRNQDRLRRRE-ERER-EERLSRRSGSRTRDRRRSRSRDRRRRRSRSTSRE 286
           R+   E++ +R+++R + RE ERER  ER   R   R R+R R R  DR R R R   RE
Sbjct: 687 RERERERERERDREREKERELERERAREREREREKERDRERDRDRDHDRERERERERDRE 746

Query: 287 RRKLSRSRSRDRHR-RHRSRSRSHSRGHRRA-SRDR 320
           + +      R+R R R R R R   R   RA  RD+
Sbjct: 747 KEREREREERERERERERERERERERERERARERDK 782



 Score = 56.6 bits (135), Expect = 3e-08
 Identities = 35/98 (35%), Positives = 49/98 (50%), Gaps = 2/98 (2%)

Query: 226 DQLRKTVAEKQEKRNQDRLRRREEREREERLSRRSGSRTRDRRRSRSRDRRRRRSRSTSR 285
           D+ R    E++ +R +DR + RE REREER   R   R R+R R R R+R R R +   R
Sbjct: 728 DRDRDHDRERERERERDREKERE-REREERERERERERERERERERERERARERDKERER 786

Query: 286 ERRKLSRSRSRDRHRRHRSRSRSHSRGHRRASRDRSAK 323
           +R    + + RD  R  R   R   R  R    +R +K
Sbjct: 787 QRDWEDKDKGRDDRREKREEIR-EDRNPRDGHDERKSK 823



 Score = 55.1 bits (131), Expect = 8e-08
 Identities = 33/87 (37%), Positives = 43/87 (49%), Gaps = 4/87 (4%)

Query: 234 EKQEKRNQDRLRRRE-EREREERLSRRSGSRTRDRRRSRSRDRRRRRSRSTSRERRKLSR 292
           E+   R+ DR R RE ER+RE+   R    R R+R R R R+R R R R  +RER K   
Sbjct: 726 ERDRDRDHDRERERERERDREKEREREREERERERERERERERERERERERARERDK--- 782

Query: 293 SRSRDRHRRHRSRSRSHSRGHRRASRD 319
            R R R    + + R   R  R   R+
Sbjct: 783 ERERQRDWEDKDKGRDDRREKREEIRE 809



 Score = 53.1 bits (126), Expect = 3e-07
 Identities = 34/97 (35%), Positives = 55/97 (56%), Gaps = 4/97 (4%)

Query: 226 DQLRKTVAEKQEKRNQDRLRRRE-ERERE-ERLSRRSGSRTRDRR-RSRSRDRRRRRSRS 282
           ++ R+   E++++R+++R R R+ +RERE ER   R   R R+R  R R R+R R R R 
Sbjct: 710 ERAREREREREKERDRERDRDRDHDRERERERERDREKEREREREERERERERERERERE 769

Query: 283 TSRERRKLSRSRSRDRHRRHRSRSRSHSRGHRRASRD 319
             RER + +R R ++R R+     +   R  RR  R+
Sbjct: 770 RERERER-ARERDKERERQRDWEDKDKGRDDRREKRE 805



 Score = 52.4 bits (124), Expect = 6e-07
 Identities = 35/99 (35%), Positives = 49/99 (49%), Gaps = 12/99 (12%)

Query: 226 DQLRKTVAEKQEKRNQDRLRRREERERE---ERLSRRSGSRTRDRRRSRSRDRRRRR--- 279
           D  R+   E++  R ++R R REERERE   ER   R   R R+R R R ++R R+R   
Sbjct: 732 DHDRERERERERDREKEREREREERERERERERERERERERERERARERDKERERQRDWE 791

Query: 280 ----SRSTSRERRKLSRS--RSRDRHRRHRSRSRSHSRG 312
                R   RE+R+  R     RD H   +S+ R  + G
Sbjct: 792 DKDKGRDDRREKREEIREDRNPRDGHDERKSKKRYRNEG 830



 Score = 46.2 bits (108), Expect = 4e-05
 Identities = 38/91 (41%), Positives = 49/91 (53%), Gaps = 6/91 (6%)

Query: 235 KQEKRNQDRLRR-REEREREERLSRRSGSRTRDRRRSRS-RDRRRRRSRSTSRERRKLSR 292
           + E+R   R +R RE+  REER   +  S +RD R  R  RD R RR    +R+RR+L  
Sbjct: 413 RHERREDTRGKRDREKDSREEREYEQDQSSSRDHRDDREPRDGRDRRDARDTRDRRELRD 472

Query: 293 SRS-RD-RHRRHRSRSRSHSRGHR--RASRD 319
           SR  RD R  R  SR    SR  R  R++RD
Sbjct: 473 SRDMRDSREMRDYSRDTKESRDPRDSRSTRD 503



 Score = 45.1 bits (105), Expect = 9e-05
 Identities = 47/151 (31%), Positives = 65/151 (43%), Gaps = 35/151 (23%)

Query: 198 GLHDNDRRLADHFGGKLHLGFIQIREKLDQLRKTVAEKQEKRNQDRLR-RREEREREERL 256
           G HD++R    H   + H      R K D+ + +  E++ +++Q   R  R++RE  +  
Sbjct: 399 GRHDHERTSQSH--DRRHERREDTRGKRDREKDSREEREYEQDQSSSRDHRDDREPRDGR 456

Query: 257 SRRSGSRTRDRRRSR-SRDRRRRRSRSTSRERRKLSR----------SRS---------- 295
            RR    TRDRR  R SRD R       SRE R  SR          SRS          
Sbjct: 457 DRRDARDTRDRRELRDSRDMR------DSREMRDYSRDTKESRDPRDSRSTRDAHDYRDR 510

Query: 296 --RDRHRR---HRSRSRSHSRGHRRASRDRS 321
             RD HR+   +   SRS+ R H R    R+
Sbjct: 511 EGRDTHRKEDTYPEESRSYGRNHLREESSRT 541



 Score = 43.5 bits (101), Expect = 3e-04
 Identities = 30/82 (36%), Positives = 39/82 (47%), Gaps = 11/82 (13%)

Query: 234  EKQEKRNQDRLRRREEREREERLSRRSGS----RTRDRRRSRSRDRRRRRS--RSTSRER 287
            +++++   DR R RE R+  +R   R       R RDR R R R+R R R   R   RER
Sbjct: 1300 QERDRYEHDRERERERRDTRQREWDRDADKDWPRNRDRDRLRERERERERDKRRDLDRER 1359

Query: 288  RKL-----SRSRSRDRHRRHRS 304
             +L      R R RDR R   S
Sbjct: 1360 ERLISDSVERDRDRDRDRTFES 1381



 Score = 42.7 bits (99), Expect = 4e-04
 Identities = 32/79 (40%), Positives = 39/79 (49%), Gaps = 7/79 (8%)

Query: 239  RNQDRLRRREEREREERLSR-RSGSRTRDRR--RSRSRDRRRRRSRSTSRE-RRKLSRSR 294
            + +DR     ERERE R +R R   R  D+   R+R RDR R R R   R+ RR L R R
Sbjct: 1300 QERDRYEHDRERERERRDTRQREWDRDADKDWPRNRDRDRLRERERERERDKRRDLDRER 1359

Query: 295  SR---DRHRRHRSRSRSHS 310
             R   D   R R R R  +
Sbjct: 1360 ERLISDSVERDRDRDRDRT 1378



 Score = 42.0 bits (97), Expect = 7e-04
 Identities = 37/112 (33%), Positives = 50/112 (44%), Gaps = 22/112 (19%)

Query: 222 REKLDQLRKTVAEKQEKRNQDRLRRREEREREERLSR------RSGSRTRDRRRSRSR-- 273
           R+  DQ R +  E++         RR+ RER++R S       R+    RD RR   R  
Sbjct: 611 RDNRDQARDSSFERRHGERD----RRDNRERDQRPSSPIRHQGRNDELERDERREERRVD 666

Query: 274 ---DRRRRRSRSTSRERRKLSRSRSRDRHR-RHRSRSRSHSRGHRRASRDRS 321
              DRR  R+R   RER      R R+R R R R R R   +  R   R+R+
Sbjct: 667 RVDDRRDERARERDRERE-----RDRERERERERERDREREK-ERELERERA 712



 Score = 42.0 bits (97), Expect = 7e-04
 Identities = 37/108 (34%), Positives = 52/108 (48%), Gaps = 20/108 (18%)

Query: 222  REKLDQL------RKTVAEKQEKRNQDRLRRREEREREERLSRRSGS-------RTRDR- 267
            + ++DQL      R T +++Q+ R+     RR   E + ++  RSGS       + RDR 
Sbjct: 1248 KSRIDQLKRGEPSRSTSSDRQDSRSHSS--RRSSPESDRQVHSRSGSFDSRDRLQERDRY 1305

Query: 268  --RRSRSRDRRRRRSRSTSRERRK-LSRSRSRDRHR-RHRSRSRSHSR 311
               R R R+RR  R R   R+  K   R+R RDR R R R R R   R
Sbjct: 1306 EHDRERERERRDTRQREWDRDADKDWPRNRDRDRLRERERERERDKRR 1353



 Score = 41.6 bits (96), Expect = 0.001
 Identities = 48/227 (21%), Positives = 86/227 (37%), Gaps = 33/227 (14%)

Query: 98  DRRTELAKKRLAETQEEISAEVSAKAEKVHELNEEIGKLLAKAEQLGAEGNVDESQKILM 157
           +RR E    R+ + ++E + E   + E+  E   E             E   D  ++   
Sbjct: 658 ERREERRVDRVDDRRDERARERDRERERDRERERE------------RERERDREREKER 705

Query: 158 EVEKVRAKKKEAEEEYRNSMPASSFQQQKLRVCEVCSAYLGLHDNDRRLADHFGGKLHLG 217
           E+E+ RA+++E E E          +                HD +R        +    
Sbjct: 706 ELERERAREREREREKERDRERDRDRD---------------HDRERERERERDREKERE 750

Query: 218 FIQIREKLDQLRKTVAEKQEKRNQDRLRRREEREREERLSRRSGSRTRDRRRSRSRDRRR 277
             +   + ++ R+   E++ +R ++R R R ++ERE +       + RD RR +  + R 
Sbjct: 751 REREERERERERERERERERERERERARER-DKERERQRDWEDKDKGRDDRREKREEIRE 809

Query: 278 RRSRSTSRERRKLSRSRSRDRHRRHRSRSRSHSRGHRRASRDRSAKY 324
            R+     + RK     S+ R+R   S S   S   RR     S  Y
Sbjct: 810 DRNPRDGHDERK-----SKKRYRNEGSPSPRQSPKRRREHSPDSDAY 851



 Score = 41.2 bits (95), Expect = 0.001
 Identities = 41/123 (33%), Positives = 53/123 (43%), Gaps = 10/123 (8%)

Query: 200  HDNDRRLADHFGGK---LHLGFIQIREKLDQLRKTVAEKQEKRNQDRLRRREEREREERL 256
            +D+  R  D   G+   LH G  + REK   L  T    + K   D+L+R E        
Sbjct: 1211 NDSAHRSGDDQSGRKRVLHSGS-RDREKTKSLEIT---GERKSRIDQLKRGEPSRSTS-- 1264

Query: 257  SRRSGSRTRDRRRSRSRDRRRRRSRSTSRERRKLSRSRSRDRHRRHRSRSRSHSRGHRRA 316
            S R  SR+   RRS     R+  SRS S + R   + R R  H R R R R  +R  R  
Sbjct: 1265 SDRQDSRSHSSRRSSPESDRQVHSRSGSFDSRDRLQERDRYEHDRERERERRDTR-QREW 1323

Query: 317  SRD 319
             RD
Sbjct: 1324 DRD 1326



 Score = 40.4 bits (93), Expect = 0.002
 Identities = 28/85 (32%), Positives = 37/85 (43%), Gaps = 2/85 (2%)

Query: 238 KRNQDRLRRREEREREERLSRRSGSRTRDRRRSRSRDRRRRRSRST-SRERRKLSRSRSR 296
           +R Q   R R     + R      S++ DRR  R  D R +R R   SRE R+  + +S 
Sbjct: 383 QRKQSPPRHRSPMREKGRHDHERTSQSHDRRHERREDTRGKRDREKDSREEREYEQDQSS 442

Query: 297 DR-HRRHRSRSRSHSRGHRRASRDR 320
            R HR  R       R   R +RDR
Sbjct: 443 SRDHRDDREPRDGRDRRDARDTRDR 467



 Score = 39.3 bits (90), Expect = 0.005
 Identities = 31/90 (34%), Positives = 36/90 (40%), Gaps = 5/90 (5%)

Query: 233  AEKQEKRNQDRLRRREEREREERLSRRSGSRTRDRRRSRSRDRRRRRSRSTSRERRKLSR 292
            A+K   RN+DR R RE     ER  RR   R R+R  S S +R R R R      R    
Sbjct: 1327 ADKDWPRNRDRDRLRERERERERDKRRDLDRERERLISDSVERDRDRDRD-----RTFES 1381

Query: 293  SRSRDRHRRHRSRSRSHSRGHRRASRDRSA 322
            S+     R        H R     SRD  A
Sbjct: 1382 SQIESVKRCEAKLEGEHERDLESTSRDSLA 1411



 Score = 37.7 bits (86), Expect = 0.014
 Identities = 32/99 (32%), Positives = 48/99 (48%), Gaps = 5/99 (5%)

Query: 221 IREKLDQLRKTVAEKQEKRNQDRLRRREEREREERLSRRSGSRTRDRRRSRSRDRRRRRS 280
           +REK     +  ++  ++R++ R   R +R+RE+  SR    R  ++ +S SRD R  R 
Sbjct: 395 MREKGRHDHERTSQSHDRRHERREDTRGKRDREKD-SREE--REYEQDQSSSRDHRDDRE 451

Query: 281 RSTSRERRKLSRSRSRDRHRRHRSRSRSHSRGHRRASRD 319
               R+RR      +RDR     SR    SR  R  SRD
Sbjct: 452 PRDGRDRR--DARDTRDRRELRDSRDMRDSREMRDYSRD 488



 Score = 37.0 bits (84), Expect = 0.024
 Identities = 61/264 (23%), Positives = 103/264 (39%), Gaps = 43/264 (16%)

Query: 77  ERDLFFELDAMDHLESFIAECDRRTELAKKRLAETQEEISAEVSAKAEKVHELNEEIGKL 136
           ERD   E   +D ++    E  R  +  ++R  E + E   E   + EK  EL  E  + 
Sbjct: 655 ERDERREERRVDRVDDRRDERARERDRERERDRERERERERERDREREKERELERERARE 714

Query: 137 LAKAEQLGAEGNVDESQKILMEVEKVRAKKKEAEEEYRNSMPASSFQQQKLRVCEVCSAY 196
             +  +   +   D  +    E E+ R + +E E E          ++++ R  E     
Sbjct: 715 REREREKERDRERDRDRDHDRERERERERDREKEREREREERERERERERERERE----- 769

Query: 197 LGLHDNDRRLADHFGGKLHLGFIQIREKLDQLRKTVAEKQEKRNQDRLRRREEREREERL 256
               + +R  A              R+K ++ R+   E ++K   DR  +REE  RE+R 
Sbjct: 770 ---RERERERARE------------RDK-ERERQRDWEDKDKGRDDRREKREEI-REDRN 812

Query: 257 SRRSGSRTRDRRRSRSRDRRR--RRSRSTSRERRKLS-----RSRSRDRHRRHR------ 303
            R       D R+S+ R R       R + + RR+ S      +   D++ +HR      
Sbjct: 813 PRDG----HDERKSKKRYRNEGSPSPRQSPKRRREHSPDSDAYNSGDDKNEKHRLLSQVV 868

Query: 304 --SRSRSHSRGHRRASRDRSAKYK 325
               SRS S  H   + DR  ++K
Sbjct: 869 RPQESRSLSPSH--LTEDRQGRWK 890



 Score = 36.2 bits (82), Expect = 0.041
 Identities = 30/88 (34%), Positives = 40/88 (45%), Gaps = 5/88 (5%)

Query: 242  DRLRRREEREREERLSRRSGSRTRDRRRSRSRDRRRRRSRSTSRER-RKLSRSRSRDRHR 300
            D   R +ER+R E    R   R   R+R   RD  +   R+  R+R R+  R R RD+ R
Sbjct: 1294 DSRDRLQERDRYEHDRERERERRDTRQREWDRDADKDWPRNRDRDRLRERERERERDKRR 1353

Query: 301  ---RHRSRSRSHSRGHRRASRDRSAKYK 325
               R R R  S S   R   RDR   ++
Sbjct: 1354 DLDRERERLISDS-VERDRDRDRDRTFE 1380



 Score = 34.3 bits (77), Expect = 0.16
 Identities = 41/133 (30%), Positives = 54/133 (40%), Gaps = 35/133 (26%)

Query: 223  EKLDQLRKTVAEKQEKRNQDRLR-------RREEREREERL-------SRRSGSRTRDRR 268
            EK++    T+ + Q ++  D+ R       R        RL       + RSG     R+
Sbjct: 1166 EKVETPHVTIEDAQHRKPMDQKRSSSLGSNRSNRSHTSGRLRSPSNDSAHRSGDDQSGRK 1225

Query: 269  R---SRSRDRRR---------RRSRSTSRERRKLSRSRSRDRH--RRHRSRSRS------ 308
            R   S SRDR +         R+SR    +R + SRS S DR   R H SR  S      
Sbjct: 1226 RVLHSGSRDREKTKSLEITGERKSRIDQLKRGEPSRSTSSDRQDSRSHSSRRSSPESDRQ 1285

Query: 309  -HSRGHRRASRDR 320
             HSR     SRDR
Sbjct: 1286 VHSRSGSFDSRDR 1298



 Score = 32.7 bits (73), Expect = 0.45
 Identities = 61/282 (21%), Positives = 102/282 (36%), Gaps = 70/282 (24%)

Query: 110 ETQEEISAEVSAKAEKVHELNEEIGKLLAKAEQLGAEG-NVDESQKILMEVEK----VRA 164
           ET  + S       + VHEL+ E+ +   + E +  E  N+++ ++I+++ E     VR+
Sbjct: 145 ETNRDDSDNGDINYDYVHELSLEMKRQKIQRELMKLEQENMEKREEIIIKKEVSPEVVRS 204

Query: 165 K-------KKEAEEEYRNSMPASSFQQQKLRVCEVCSAYLGLHDNDRRL----------- 206
           K       +K ++   R S P SS   +K R     S+ L     + +            
Sbjct: 205 KLSPSPSLRKSSKSPKRKSSPKSSSASKKDRKTSAVSSPLLDQQRNSKTNQSKKKGPRTP 264

Query: 207 -------ADHFGGKLHLGFIQIREKLDQLRKTVAEKQEKRNQDRLRRREERERE------ 253
                   D   GK +    ++++++++  KT   K   R+ +R R + ++ R       
Sbjct: 265 SPPPPIPEDIALGKKYKEKYKVKDRIEE--KTRDGKDRGRDFERQREKRDKPRSTSPAGQ 322

Query: 254 -----------------ERLSRRSGSRTRDRRRSRSRDR------RRRRSRSTSRERRKL 290
                              + R S S  R R  S S  R      RR  S   S      
Sbjct: 323 HHSPISSRHHSSSSQSGSSIQRHSPSPRRKRTPSPSYQRTLTPPLRRSASPYPSHSLSSP 382

Query: 291 SRSRSRDRHRR---------HRSRSRSHSRGHRRASRDRSAK 323
            R +S  RHR          H   S+SH R H R    R  +
Sbjct: 383 QRKQSPPRHRSPMREKGRHDHERTSQSHDRRHERREDTRGKR 424



 Score = 30.4 bits (67), Expect = 2.2
 Identities = 30/113 (26%), Positives = 43/113 (38%), Gaps = 10/113 (8%)

Query: 222 REKLDQLRKTVAEKQEKRNQDRLRRREEREREERLSRRSGSRTRDRRRSRSRDRRRRRSR 281
           RE  D  R T   +  + ++      + R+RE R + R      +  RS  R+  R  S 
Sbjct: 480 REMRDYSRDTKESRDPRDSRSTRDAHDYRDREGRDTHRKEDTYPEESRSYGRNHLREESS 539

Query: 282 STS--RERRKLSRS--------RSRDRHRRHRSRSRSHSRGHRRASRDRSAKY 324
            T    E R  SRS        RSR R      +    SRG +  S   ++ Y
Sbjct: 540 RTEIRNESRNESRSEIRNDRMGRSRGRVPELPEKGSRGSRGSQIDSHSSNSNY 592



 Score = 30.0 bits (66), Expect = 2.9
 Identities = 26/81 (32%), Positives = 35/81 (43%), Gaps = 8/81 (9%)

Query: 240  NQDRLRRREEREREERLSRRSGSRTRDRRRSRSRDRRRRRSRSTSRERRKLSRSRSRDRH 299
            ++DR + +      ER SR    +  +  RS S DR+  RS S        SR  S +  
Sbjct: 1232 SRDREKTKSLEITGERKSRIDQLKRGEPSRSTSSDRQDSRSHS--------SRRSSPESD 1283

Query: 300  RRHRSRSRSHSRGHRRASRDR 320
            R+  SRS S     R   RDR
Sbjct: 1284 RQVHSRSGSFDSRDRLQERDR 1304


>gi|20127499 arginine/serine-rich splicing factor 6 [Homo sapiens]
          Length = 344

 Score = 62.8 bits (151), Expect = 4e-10
 Identities = 44/115 (38%), Positives = 59/115 (51%), Gaps = 4/115 (3%)

Query: 207 ADHFGGKLHLGFIQIREKLDQLRKTVAEKQEKRNQDRLRRREEREREERLSRRSGSRTRD 266
           AD    + + G I+ R   D  R        + N   +R  E++ R       SGSR+R 
Sbjct: 139 ADAHKERTNEGVIEFRSYSDMKRALDKLDGTEINGRNIRLIEDKPRTSHRRSYSGSRSRS 198

Query: 267 RRRSRSRDRRRRRSRSTSRERRKLSRSRSRDRHRRHRSRSRSHSRGHRRASRDRS 321
           R R RSR R RR SRS S   R +S+SRSR R  R + RSRS S+G +  S+ +S
Sbjct: 199 RSRRRSRSRSRRSSRSRS---RSISKSRSRSR-SRSKGRSRSRSKGRKSRSKSKS 249



 Score = 57.0 bits (136), Expect = 2e-08
 Identities = 40/90 (44%), Positives = 50/90 (55%), Gaps = 7/90 (7%)

Query: 239 RNQDRLRRREEREREERLSRRSGSRTRDRRRSRSRDRRRRRSRSTSRERRKLSRSRS--- 295
           R++ R RRR  R R  R S RS SR+  + RSRSR R + RSRS S+ R+  S+S+S   
Sbjct: 195 RSRSRSRRRS-RSRSRR-SSRSRSRSISKSRSRSRSRSKGRSRSRSKGRKSRSKSKSKPK 252

Query: 296 --RDRHRRHRSRSRSHSRGHRRASRDRSAK 323
             R  H   RSRS+      R  SR RS K
Sbjct: 253 SDRGSHSHSRSRSKDEYEKSRSRSRSRSPK 282



 Score = 55.8 bits (133), Expect = 5e-08
 Identities = 47/170 (27%), Positives = 76/170 (44%), Gaps = 13/170 (7%)

Query: 154 KILMEVEKVRAKKKEAEEEYRNSMPASSFQQQKLRVCEVCSAYLGLHDNDRRLADHFGGK 213
           ++++E    R   ++ ++  R +   +     K R  E    +    D  R L    G +
Sbjct: 111 RLIVENLSSRCSWQDLKDFMRQAGEVTYADAHKERTNEGVIEFRSYSDMKRALDKLDGTE 170

Query: 214 LH---LGFIQIREKLDQLRKTVAEKQEKRNQDRLRRREEREREERLSRRSGSRTRDRRRS 270
           ++   +  I+ + +    R     +   R++ R R R  R    R    S SR+R R RS
Sbjct: 171 INGRNIRLIEDKPRTSHRRSYSGSRSRSRSRRRSRSRSRRSSRSRSRSISKSRSRSRSRS 230

Query: 271 RSRDRRR---RRSRSTSRERRKL-------SRSRSRDRHRRHRSRSRSHS 310
           + R R R   R+SRS S+ + K        SRSRS+D + + RSRSRS S
Sbjct: 231 KGRSRSRSKGRKSRSKSKSKPKSDRGSHSHSRSRSKDEYEKSRSRSRSRS 280



 Score = 51.6 bits (122), Expect = 9e-07
 Identities = 36/87 (41%), Positives = 46/87 (52%), Gaps = 2/87 (2%)

Query: 236 QEKRNQDRLRRREEREREERLSRRSGSRTRDRRRSRSRDRRRRRSRSTSRERRKLSRSRS 295
           ++K      R         R  RRS SR+R   RSRSR   + RSRS SR + + SRSRS
Sbjct: 180 EDKPRTSHRRSYSGSRSRSRSRRRSRSRSRRSSRSRSRSISKSRSRSRSRSKGR-SRSRS 238

Query: 296 RDRHRRHRSRSRSHS-RGHRRASRDRS 321
           + R  R +S+S+  S RG    SR RS
Sbjct: 239 KGRKSRSKSKSKPKSDRGSHSHSRSRS 265



 Score = 40.8 bits (94), Expect = 0.002
 Identities = 35/104 (33%), Positives = 48/104 (46%), Gaps = 22/104 (21%)

Query: 229 RKTVAEKQEKRNQDRLRRREEREREERLSRRSGSRTRDRR---------RSRSRDRRRRR 279
           RK+ ++ + K   DR      R R +    +S SR+R R          +S+SR R + R
Sbjct: 241 RKSRSKSKSKPKSDRGSHSHSRSRSKDEYEKSRSRSRSRSPKENGKGDIKSKSRSRSQSR 300

Query: 280 SRS------------TSRERRKLSRSRSRDRHRRHRSRSRSHSR 311
           S S            +   +R  SRSRSR R +  RSRSRS SR
Sbjct: 301 SNSPLPVPPSKARSVSPPPKRATSRSRSRSRSKS-RSRSRSSSR 343



 Score = 30.0 bits (66), Expect = 2.9
 Identities = 14/24 (58%), Positives = 17/24 (70%)

Query: 263 RTRDRRRSRSRDRRRRRSRSTSRE 286
           R   R RSRSR + R RSRS+SR+
Sbjct: 321 RATSRSRSRSRSKSRSRSRSSSRD 344


>gi|41327771 DEAD (Asp-Glu-Ala-Asp) box polypeptide 23 [Homo
           sapiens]
          Length = 820

 Score = 62.8 bits (151), Expect = 4e-10
 Identities = 36/87 (41%), Positives = 46/87 (52%), Gaps = 2/87 (2%)

Query: 234 EKQEKRNQDRLRRREEREREERLSRRSGSRTRDRRRSRSRDRRRRRSRSTSRERRKLSRS 293
           E++  R  DR R R+   +      R   R+RDRRR  SR R R RS+S  RERR   R 
Sbjct: 19  ERKRSRTPDRERDRDRDRKSSPSKDRKRHRSRDRRRGGSRSRSRSRSKSAERERRHKERE 78

Query: 294 RSRDRHRRHRSRSRSHSRGHRRASRDR 320
           R ++R R  + R R    GHRR  +DR
Sbjct: 79  RDKERDRNKKDRDRDKD-GHRR-DKDR 103



 Score = 60.8 bits (146), Expect = 2e-09
 Identities = 37/109 (33%), Positives = 57/109 (52%), Gaps = 9/109 (8%)

Query: 224 KLDQLRKTVAEKQEKRNQDRLRR--REEREREERLSRRSGSRTRDRRRSRSRDRRRR--- 278
           K ++ R    +++  R++DR     ++ +    R  RR GSR+R R RS+S +R RR   
Sbjct: 17  KEERKRSRTPDRERDRDRDRKSSPSKDRKRHRSRDRRRGGSRSRSRSRSKSAERERRHKE 76

Query: 279 RSRSTSRERRKLSRSRSRDRHRRHRSRSRSHSRGHR----RASRDRSAK 323
           R R   R+R K  R R +D HRR + R RS     R    ++ +DR +K
Sbjct: 77  RERDKERDRNKKDRDRDKDGHRRDKDRKRSSLSPGRGKDFKSRKDRDSK 125



 Score = 59.7 bits (143), Expect = 3e-09
 Identities = 37/94 (39%), Positives = 52/94 (55%), Gaps = 12/94 (12%)

Query: 234 EKQEKRNQDRLRRREEREREERLSRRSGSRTRDRRRSRSRDRRRRRSRSTSRERRK---- 289
           E  +K+++D    +EER+R  R   R   R RDR+ S S+DR+R RS    R+RR+    
Sbjct: 4   ELADKKDRDASPSKEERKRS-RTPDRERDRDRDRKSSPSKDRKRHRS----RDRRRGGSR 58

Query: 290 ---LSRSRSRDRHRRHRSRSRSHSRGHRRASRDR 320
               SRS+S +R RRH+ R R   R   +  RDR
Sbjct: 59  SRSRSRSKSAERERRHKERERDKERDRNKKDRDR 92



 Score = 34.3 bits (77), Expect = 0.16
 Identities = 21/93 (22%), Positives = 45/93 (48%), Gaps = 11/93 (11%)

Query: 222 REKLDQLRKTVAEKQEKRNQ---------DRLRRREEREREERLSRRSGSRTRDRRRSRS 272
           ++++++ ++ + E+++KR Q         +  + RE RER ER+ R +     +  R + 
Sbjct: 178 QQEVEERQRMLEEERKKRKQFQDLGRKMLEDPQERERRERRERMERETNGNEDEEGRQKI 237

Query: 273 RDRRRRRSRSTSRERRKLS--RSRSRDRHRRHR 303
           R+ + +     + + R L   + R R RH   R
Sbjct: 238 REEKDKSKELHAIKERYLGGIKKRRRTRHLNDR 270



 Score = 33.9 bits (76), Expect = 0.20
 Identities = 31/105 (29%), Positives = 43/105 (40%), Gaps = 22/105 (20%)

Query: 226 DQLRKTVAEKQEKRNQDRLRRR-------------EEREREERLSRRSGSRTR---DRRR 269
           D+ RK+   K  KR++ R RRR              ERER  +   R   R R   DR R
Sbjct: 33  DRDRKSSPSKDRKRHRSRDRRRGGSRSRSRSRSKSAERERRHKERERDKERDRNKKDRDR 92

Query: 270 SRSRDRRRRRSRSTSRERRKLSRSRSRD-RHRRHRSRSRSHSRGH 313
            +   RR +      R+R  LS  R +D + R+ R   +     H
Sbjct: 93  DKDGHRRDK-----DRKRSSLSPGRGKDFKSRKDRDSKKDEEDEH 132



 Score = 30.4 bits (67), Expect = 2.2
 Identities = 19/98 (19%), Positives = 43/98 (43%), Gaps = 4/98 (4%)

Query: 223 EKLDQLRKTVAEKQEKRNQDRLRRREEREREERLSRRSGSRTRDRRRSRSRDRRRRRSRS 282
           E L + ++ V E+Q    ++R +R++ ++    L R+     ++R R   R+R  R +  
Sbjct: 172 EALKRRQQEVEERQRMLEEERKKRKQFQD----LGRKMLEDPQERERRERRERMERETNG 227

Query: 283 TSRERRKLSRSRSRDRHRRHRSRSRSHSRGHRRASRDR 320
              E  +      +D+ +   +    +  G ++  R R
Sbjct: 228 NEDEEGRQKIREEKDKSKELHAIKERYLGGIKKRRRTR 265



 Score = 29.6 bits (65), Expect = 3.8
 Identities = 23/90 (25%), Positives = 38/90 (42%), Gaps = 5/90 (5%)

Query: 233 AEKQEKRNQDRLRRREERER--EERLSRRSGSRTRDRRRSRSRDRRRRRSRSTSRERRKL 290
           AE++ +  + R +  EER+R  EE   +R   +   R+       R RR R   RER + 
Sbjct: 167 AEREAEALKRRQQEVEERQRMLEEERKKRKQFQDLGRKMLEDPQERERRER---RERMER 223

Query: 291 SRSRSRDRHRRHRSRSRSHSRGHRRASRDR 320
             + + D   R + R          A ++R
Sbjct: 224 ETNGNEDEEGRQKIREEKDKSKELHAIKER 253



 Score = 28.5 bits (62), Expect = 8.5
 Identities = 18/92 (19%), Positives = 35/92 (38%), Gaps = 6/92 (6%)

Query: 234 EKQEKRNQDRLRRREEREREERLSRRSGSRTRDRRRSRSRDRRRRRSRSTSRERRKLSRS 293
           +K E+  + + +   + ERE    +R      +R+R    +R++R      ++ + L R 
Sbjct: 151 KKAEEEAEAKPKFLSKAEREAEALKRRQQEVEERQRMLEEERKKR------KQFQDLGRK 204

Query: 294 RSRDRHRRHRSRSRSHSRGHRRASRDRSAKYK 325
              D   R R   R         + D   + K
Sbjct: 205 MLEDPQERERRERRERMERETNGNEDEEGRQK 236


>gi|4759100 splicing factor, arginine/serine-rich 11 [Homo sapiens]
          Length = 484

 Score = 62.4 bits (150), Expect = 5e-10
 Identities = 36/99 (36%), Positives = 51/99 (51%), Gaps = 10/99 (10%)

Query: 234 EKQEKRNQDRLRRREERER----------EERLSRRSGSRTRDRRRSRSRDRRRRRSRST 283
           +K+EKR   R R R  R R            R  RRS S++R RRRS+S  RRR  SR  
Sbjct: 241 KKEEKRRHSRSRSRSRRRRTPSSSRHRRSRSRSRRRSHSKSRSRRRSKSPRRRRSHSRER 300

Query: 284 SRERRKLSRSRSRDRHRRHRSRSRSHSRGHRRASRDRSA 322
            R  R  S++R + +  + + RS++  + +  A R RSA
Sbjct: 301 GRRSRSTSKTRDKKKEDKEKKRSKTPPKSYSTARRSRSA 339



 Score = 58.9 bits (141), Expect = 6e-09
 Identities = 44/107 (41%), Positives = 55/107 (51%), Gaps = 4/107 (3%)

Query: 217 GFIQIREKLDQLRKTVAE--KQEKRNQDRLRRREEREREERLSRRSGSRTRDRRRSRSRD 274
           G +    K D   K + E  K+ +  Q  +    E +++E   R S SR+R RRR     
Sbjct: 204 GLVSPSLKSDTSSKEIEEAMKRVREAQSLISAAIEPDKKEEKRRHSRSRSRSRRRRTPSS 263

Query: 275 RRRRRSRSTSRERRKLSRSRSRDRHRRHRSRSRSHSRGHRRASRDRS 321
            R RRSRS SR RR  S+SRSR R +  R R RSHSR   R SR  S
Sbjct: 264 SRHRRSRSRSR-RRSHSKSRSRRRSKSPR-RRRSHSRERGRRSRSTS 308



 Score = 58.2 bits (139), Expect = 1e-08
 Identities = 41/133 (30%), Positives = 59/133 (44%), Gaps = 29/133 (21%)

Query: 222 REKLDQLRKTVAEKQEKRNQDRLRRREEREREERLSRRSGSRTRDRR------------- 268
           R +    R++ ++ + +R     RRR    RE     RS S+TRD++             
Sbjct: 268 RSRSRSRRRSHSKSRSRRRSKSPRRRRSHSRERGRRSRSTSKTRDKKKEDKEKKRSKTPP 327

Query: 269 ---------RSRSRDRRRRRSRSTSRE-------RRKLSRSRSRDRHRRHRSRSRSHSRG 312
                    RS SR+RRRRRSRS +R        +RKLSRS S  RH++ + + +   R 
Sbjct: 328 KSYSTARRSRSASRERRRRRSRSGTRSPKKPRSPKRKLSRSPSPRRHKKEKKKDKDKERS 387

Query: 313 HRRASRDRSAKYK 325
                R  S K K
Sbjct: 388 RDERERSTSKKKK 400



 Score = 37.7 bits (86), Expect = 0.014
 Identities = 30/116 (25%), Positives = 49/116 (42%), Gaps = 9/116 (7%)

Query: 161 KVRAKKKEAEEEYRNSMPASSFQQQKLRVCEVCSAYLGLHDNDRRLADHFGGKLHLGFIQ 220
           K R KKKE +E+ R+  P  S+   +                 RR     G +       
Sbjct: 309 KTRDKKKEDKEKKRSKTPPKSYSTARRS--------RSASRERRRRRSRSGTRSPKKPRS 360

Query: 221 IREKLDQLRKTVAEKQEKR-NQDRLRRREEREREERLSRRSGSRTRDRRRSRSRDR 275
            + KL +       K+EK+ ++D+ R R+ERER     ++S  + +DR R    D+
Sbjct: 361 PKRKLSRSPSPRRHKKEKKKDKDKERSRDERERSTSKKKKSKDKEKDRERKSESDK 416



 Score = 37.7 bits (86), Expect = 0.014
 Identities = 21/80 (26%), Positives = 39/80 (48%), Gaps = 4/80 (5%)

Query: 229 RKTVAEKQEKRNQDRLRRR---EEREREERLSRRSGSRTRDRRRSRSRDRRRRR-SRSTS 284
           R   A ++ +R + R   R   + R  + +LSR    R   + + + +D+ R R  R  S
Sbjct: 335 RSRSASRERRRRRSRSGTRSPKKPRSPKRKLSRSPSPRRHKKEKKKDKDKERSRDERERS 394

Query: 285 RERRKLSRSRSRDRHRRHRS 304
             ++K S+ + +DR R+  S
Sbjct: 395 TSKKKKSKDKEKDRERKSES 414


>gi|4827046 U2 small nuclear RNA auxiliary factor 1-like 2 [Homo
           sapiens]
          Length = 482

 Score = 62.0 bits (149), Expect = 7e-10
 Identities = 40/88 (45%), Positives = 50/88 (56%), Gaps = 2/88 (2%)

Query: 238 KRNQDRLRRREEREREERLSRRSGSRTRDRRRSRSRDRRRRRSRSTSRERRKLSRSRS-R 296
           KRN +  R+      ++   R S SR R   RSR R+R R R RS  R  R  SRSRS R
Sbjct: 390 KRNGESERKSSRHRGKKSHKRTSKSRERHNSRSRGRNRDRSRDRSRGRGSRSRSRSRSRR 449

Query: 297 DRHRRHRSRSRSHSRGHRRA-SRDRSAK 323
            R  R +S SRS SRG RR+ +RDR+ +
Sbjct: 450 SRRSRSQSSSRSRSRGRRRSGNRDRTVQ 477



 Score = 45.8 bits (107), Expect = 5e-05
 Identities = 42/108 (38%), Positives = 55/108 (50%), Gaps = 26/108 (24%)

Query: 201 DNDRRLADHFGGKLHLGFIQIREKLDQLRKTVAEKQEKRNQDRLRRREEREREERLSRRS 260
           +++R+ + H G K H    + RE+ +        +   RN+DR R R         SR  
Sbjct: 394 ESERKSSRHRGKKSHKRTSKSRERHNS-------RSRGRNRDRSRDR---------SRGR 437

Query: 261 GSRTRDRRRSRSRDRRRRRSRSTSRERRKLSRSRSRDRHRRHRSRSRS 308
           GSR+    RSRSR RR RRSRS S      SRSRSR R RR  +R R+
Sbjct: 438 GSRS----RSRSRSRRSRRSRSQSS-----SRSRSRGR-RRSGNRDRT 475



 Score = 28.9 bits (63), Expect = 6.5
 Identities = 11/56 (19%), Positives = 32/56 (57%)

Query: 220 QIREKLDQLRKTVAEKQEKRNQDRLRRREEREREERLSRRSGSRTRDRRRSRSRDR 275
           +I+++ ++  K   E+QE++ +++   ++ +EREE   +R   + ++    +  D+
Sbjct: 87  RIKKEKEEAAKKRQEEQERKLKEQWEEQQRKEREEEEQKRQEKKEKEEALQKMLDQ 142


>gi|24762236 PRP38 pre-mRNA processing factor 38 (yeast) domain
           containing A [Homo sapiens]
          Length = 312

 Score = 62.0 bits (149), Expect = 7e-10
 Identities = 55/179 (30%), Positives = 79/179 (44%), Gaps = 23/179 (12%)

Query: 158 EVEKVRAKKKEAEEEYRNSMPASSFQQQKL---RVCEVCSAYLGLHDNDRRLADHFGGKL 214
           +  K++++ +  E E    M    F  + L   RVC++    L      +R       +L
Sbjct: 126 DYRKIKSQNRNGEFEL---MHVDEFIDELLHSERVCDIILPRL-----QKRYVLEEAEQL 177

Query: 215 HLGFIQIREKLDQLRKTVAEKQEKRNQDRLRRREEREREER-LSRRSGSRTRDRRRSRSR 273
                 + E +D +  +  E++E    +R+   + R R  R L +   S T   RRSRSR
Sbjct: 178 EPRVSALEEDMDDVESSEEEEEEDEKLERVPSPDHRRRSYRDLDKPRRSPTLRYRRSRSR 237

Query: 274 DRRRR------RSRSTSRERRKLS-----RSRSRDRHRRHRSRSRSHSRGHRRASRDRS 321
             RRR      RS S  RER +       RSRSRDR  R RS+S  H R HR  S  +S
Sbjct: 238 SPRRRSRSPKRRSPSPRRERHRSKSPRRHRSRSRDRRHRSRSKSPGHHRSHRHRSHSKS 296



 Score = 61.2 bits (147), Expect = 1e-09
 Identities = 38/99 (38%), Positives = 49/99 (49%), Gaps = 1/99 (1%)

Query: 226 DQLRKTVAEKQEKRNQDRLRRREEREREERLSRRSGSR-TRDRRRSRSRDRRRRRSRSTS 284
           D  R++  +  + R    LR R  R R  R   RS  R +   RR R R +  RR RS S
Sbjct: 211 DHRRRSYRDLDKPRRSPTLRYRRSRSRSPRRRSRSPKRRSPSPRRERHRSKSPRRHRSRS 270

Query: 285 RERRKLSRSRSRDRHRRHRSRSRSHSRGHRRASRDRSAK 323
           R+RR  SRS+S   HR HR RS S S    + S  +S +
Sbjct: 271 RDRRHRSRSKSPGHHRSHRHRSHSKSPERSKKSHKKSRR 309


>gi|148746195 trichohyalin [Homo sapiens]
          Length = 1943

 Score = 61.6 bits (148), Expect = 9e-10
 Identities = 50/222 (22%), Positives = 96/222 (43%), Gaps = 12/222 (5%)

Query: 98  DRRTELAKKRLAETQEEISAEVSAKAEKVHELNEEIGKLLAKAEQLGAEGNVDESQKILM 157
           +RR  L ++   E  E+   +   K ++  E  E   KL    E+   E      Q++  
Sbjct: 453 ERRDWLKREEETERHEQERRKQQLKRDQEEERRERWLKL---EEEERREQQERREQQLRR 509

Query: 158 EVEKVRAKKKEAEEEYRNSMPASSFQQQKLRVCEVCSAYLGLHDNDRRLADHFGGKLHLG 217
           E E+ R ++ + +EE          +QQ  R  E     L   + ++RL      +    
Sbjct: 510 EQEERREQRLKRQEEEERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQERREQ---- 565

Query: 218 FIQIREKLDQLRKTVAEKQEKRNQDRLRRREEREREERLSRRSGSRTRDRRRSRSRDRRR 277
             +++ + ++ R  + +++E+R Q RL+R +E   E+RL R    R     R   R++R 
Sbjct: 566 --RLKREQEERRDQLLKREEERRQQRLKREQEERLEQRLKREEVERLEQEER---REQRL 620

Query: 278 RRSRSTSRERRKLSRSRSRDRHRRHRSRSRSHSRGHRRASRD 319
           +R       R++L +S  ++  R+ + R     R  +R  R+
Sbjct: 621 KREEPEEERRQQLLKSEEQEERRQQQLRREQQERREQRLKRE 662



 Score = 54.7 bits (130), Expect = 1e-07
 Identities = 54/250 (21%), Positives = 110/250 (44%), Gaps = 25/250 (10%)

Query: 91  ESFIAECDRRTELAKKRLAETQEEISAEVSAKAEKVHELNEEIGKLLAKAEQLGA----- 145
           E  +AE + ++E  ++     ++    E+  + ++  E  E      A+ EQL +     
Sbjct: 145 ERELAEGEEQSEKQERLEQRDRQRRDEELWRQRQEWQEREER----RAEEEQLQSCKGHE 200

Query: 146 -EGNVDESQKILMEVEKVRAKKKEAEEEYRNSMPASSFQQQKLRVCEVCSAYLGLHDNDR 204
            E   DE Q    E+ ++R K +E +++ R       FQ+++ +  E       L   + 
Sbjct: 201 TEEFPDEEQLRRRELLELRRKGREEKQQQRRERQDRVFQEEEEK--EWRKRETVLRKEEE 258

Query: 205 RLADHFGGKLHLGFIQIREKLDQLRKTVAEK------QEKRNQDRLRRREE---REREER 255
           +L +    +      +++E+ +QLRK   ++      +E++ Q RLRR ++   ++ EER
Sbjct: 259 KLQEEEPQRQR----ELQEEEEQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEEER 314

Query: 256 LSRRSGSRTRDRRRSRSRDRRRRRSRSTSRERRKLSRSRSRDRHRRHRSRSRSHSRGHRR 315
             ++   R +  RR +  +RR ++ R    ERR+    R ++  RR +   R      R 
Sbjct: 315 REQQEERREQQERREQQEERREQQLRREQEERREQQLRREQEEERREQQLRREQEEERRE 374

Query: 316 ASRDRSAKYK 325
               R  + +
Sbjct: 375 QQLRREQQLR 384



 Score = 54.7 bits (130), Expect = 1e-07
 Identities = 51/221 (23%), Positives = 97/221 (43%), Gaps = 30/221 (13%)

Query: 108 LAETQEEISAEVSAKAEKVHELNEEIGKLLAKAEQLGAEGNVDESQKILMEVEKVRAKKK 167
           L + +E++  E   +  ++ E  E++ KL  + ++L  E   +E Q+  +  E+   +K+
Sbjct: 253 LRKEEEKLQEEEPQRQRELQEEEEQLRKL--ERQELRRERQEEEQQQQRLRREQQLRRKQ 310

Query: 168 EAEEEYRNSMPASSFQQQKLRVCEVCSAYLGLHDNDRRLADHFGGKLHLGFIQIREKLDQ 227
           E E            QQ++ R              +RR       +  L   Q   +  Q
Sbjct: 311 EEERRE---------QQEERR-----------EQQERREQQEERREQQLRREQEERREQQ 350

Query: 228 LRKTVAEKQEKRNQDRLRRREEREREERLSRRSGSRTRDRRRSRSRDRRR----RRSRST 283
           LR+   E++E+R + +LRR +E ER E+  RR     R+++  R +  RR    RR +  
Sbjct: 351 LRR---EQEEERREQQLRREQEEERREQQLRREQQLRREQQLRREQQLRREQQLRREQQL 407

Query: 284 SRERR-KLSRSRSRDRHRRHRSRSRSHSRGHRRASRDRSAK 323
            RE++ +  +   R++  R       H + H +  R++  K
Sbjct: 408 RREQQLRREQQLRREQQLRREQEEERHEQKHEQERREQRLK 448



 Score = 53.9 bits (128), Expect = 2e-07
 Identities = 49/225 (21%), Positives = 96/225 (42%), Gaps = 30/225 (13%)

Query: 99  RRTELAKKRLAETQEEISAEVSAKAEKVHELNEEIGKLLAKAEQLGAEGNVDESQKILME 158
           R  +L +++    ++++  E   + E+  E +E+      K EQ   E      Q++  E
Sbjct: 403 REQQLRREQQLRREQQLRREQQLRREQEEERHEQ------KHEQERRE------QRLKRE 450

Query: 159 VEKVRAKKKEAEEEYRNSMPASSFQQQKLRVCEVCSAYLGLHDNDRRLADHFGGKLHLGF 218
            E+ R   K  EE  R+       Q ++ +  E    +L L + +RR             
Sbjct: 451 QEERRDWLKREEETERHEQERRKQQLKRDQEEERRERWLKLEEEERR------------- 497

Query: 219 IQIREKLDQLRKTVAEKQEKRNQDRLRRREEREREERLSRRSGSRTRDRRRSRSRDRRRR 278
               E+ ++  + +  +QE+R + RL+R+EE ER ++  R      R++   R +  +R 
Sbjct: 498 ----EQQERREQQLRREQEERREQRLKRQEEEERLQQRLRSEQQLRREQEERREQLLKRE 553

Query: 279 RSRSTSRERRKLSRSRSRDRHRRHRSRSRSHSRGHRRASRDRSAK 323
             +   +ERR+  R +     RR +   R   R  +R  R++  +
Sbjct: 554 EEKRLEQERRE-QRLKREQEERRDQLLKREEERRQQRLKREQEER 597



 Score = 52.4 bits (124), Expect = 6e-07
 Identities = 53/226 (23%), Positives = 99/226 (43%), Gaps = 33/226 (14%)

Query: 102 ELAKKRLAETQEEISAEVSAKAEKVHE--LNEEIGKLLAKAEQLGAEGNVDESQKILMEV 159
           E  +++  E Q+ +  E   K  +  E  L +E  KL  +  Q   E   +E Q   +E 
Sbjct: 224 EEKQQQRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQRELQEEEEQLRKLER 283

Query: 160 EKVRAKKKEAEEEYRNSMPASSFQQQKLRVCEVCSAYLGLHDNDRRLADHFGGKLHLGFI 219
           +++R +++E E+           QQQ+LR  +         + +RR              
Sbjct: 284 QELRRERQEEEQ-----------QQQRLRREQQLRRK---QEEERRE------------- 316

Query: 220 QIREKLDQLRKTVAEKQEKRNQDRLRRREEREREERLSRRSGSRTRDR--RRSRSRDRRR 277
           Q  E+ +Q  +   E+QE+R + +LRR +E  RE++L R      R++  RR +  +RR 
Sbjct: 317 QQEERREQQERR--EQQEERREQQLRREQEERREQQLRREQEEERREQQLRREQEEERRE 374

Query: 278 RRSRSTSRERRKLSRSRSRDRHRRHRSRSRSHSRGHRRASRDRSAK 323
           ++ R   + RR+    R +   R  + R     R  ++  R++  +
Sbjct: 375 QQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLR 420



 Score = 50.1 bits (118), Expect = 3e-06
 Identities = 51/212 (24%), Positives = 95/212 (44%), Gaps = 37/212 (17%)

Query: 99   RRTELAKKRLAETQEEISAEVSAKAEKVHELNEEIGKLLAKAEQLGAEGNVDESQKILME 158
            RR E  +K L E Q+        + E+  +  EE   L  + EQ       +  +K L E
Sbjct: 1440 RRQERERKFLEEEQQ-------LRQERHRKFREEEQLLQEREEQ--QLHRQERDRKFLEE 1490

Query: 159  VEKVRAKKKEA---EEEYRNSMPASSFQQQKLRVCEVCSAYLGLHDNDRRLADHFGGKLH 215
             +++R ++++    E+E R+  P   F +++ +          LH   R+          
Sbjct: 1491 EQQLRRQERDRKFREQELRSQEPERKFLEEEQQ----------LHRQQRQRK-------- 1532

Query: 216  LGFIQIREKLDQLRKTVAEKQEKRNQDRLRRREEREREERLSRRSGSRTRDR--RRSRSR 273
              F+Q  +   QLR+    +Q ++++DR  R EE+ R+ER  ++   + RDR  R    +
Sbjct: 1533 --FLQEEQ---QLRRQERGQQRRQDRDRKFREEEQLRQEREEQQLSRQERDRKFRLEEQK 1587

Query: 274  DRRRRRSRSTSRERRKLSRSRSRDRHRRHRSR 305
             RR+ + R    + ++L R   + + R+ R R
Sbjct: 1588 VRRQEQERKFMEDEQQLRRQEGQQQLRQERDR 1619



 Score = 49.3 bits (116), Expect = 5e-06
 Identities = 55/224 (24%), Positives = 97/224 (43%), Gaps = 13/224 (5%)

Query: 98  DRRTELAKKRLAETQEEISAEVSAKAEKVHELNEEIGKLLAKAEQLGAEGNVDESQKILM 157
           +RR +  K++  E +E +   + ++ +   E  E   +LL + E+   E    E Q++  
Sbjct: 513 ERREQRLKRQ--EEEERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQERRE-QRLKR 569

Query: 158 EVEKVRAKKKEAEEEYRNSMPASSFQQQKLRVCEVCSAYLGLHDNDRRLADHFGGKLHLG 217
           E E+ R +  + EEE R        Q+++L           L   +RR       +    
Sbjct: 570 EQEERRDQLLKREEE-RRQQRLKREQEERLEQRLKREEVERLEQEERREQRLKREEPE-- 626

Query: 218 FIQIREKLDQLRKTVAEKQEKRNQDRLRRREEREREERLSRRSGSRTRDRRRSRSRDRRR 277
                E+  QL K+  E+QE+R Q +LRR ++  RE+RL R       ++R  R  +  R
Sbjct: 627 ----EERRQQLLKS--EEQEERRQQQLRREQQERREQRLKREEEEERLEQRLKREHEEER 680

Query: 278 RRSRSTSRERRKL-SRSRSRDRHRRHRSRSRSHSRGHRRASRDR 320
           R       E+ +   R +SR    + +  S + +R  +  SR R
Sbjct: 681 REQELAEEEQEQARERIKSRIPKWQWQLESEADARQSKVYSRPR 724



 Score = 48.9 bits (115), Expect = 6e-06
 Identities = 52/240 (21%), Positives = 98/240 (40%), Gaps = 42/240 (17%)

Query: 99  RRTELAKKRLAETQEEISAEVSAKAEKVHELNEEIGKLLAKAEQLGAEGNVDESQKILME 158
           R  E  +++L + +EE   E   + +++    EE    L K E+   +  +   Q+  +E
Sbjct: 540 REQEERREQLLKREEEKRLEQERREQRLKREQEERRDQLLKREEERRQQRLKREQEERLE 599

Query: 159 -------VEKV--------RAKKKEAEEEYRNSMPASSFQQQKLRVCEVCSAYLGLHDND 203
                  VE++        R K++E EEE R  +  S  Q+++ +        L     +
Sbjct: 600 QRLKREEVERLEQEERREQRLKREEPEEERRQQLLKSEEQEERRQ------QQLRREQQE 653

Query: 204 RRLADHFGGKLHLGFIQIREKLDQLRKTVAEKQEKRNQDRLRRREEREREERLSRR---- 259
           RR       +  L   +  E+L+Q  K   E +E+R +  L   E+ +  ER+  R    
Sbjct: 654 RR-------EQRLKREEEEERLEQRLKR--EHEEERREQELAEEEQEQARERIKSRIPKW 704

Query: 260 --------SGSRTRDRRRSRSRDRRRRRSRSTSRERRKLSRSRSRDRHRRHRSRSRSHSR 311
                      +++   R R ++ +RRR     + RR+ S  + ++  R HR +     R
Sbjct: 705 QWQLESEADARQSKVYSRPRKQEGQRRRQEQEEKRRRRESELQWQEEERAHRQQQEEEQR 764



 Score = 48.1 bits (113), Expect = 1e-05
 Identities = 58/262 (22%), Positives = 108/262 (41%), Gaps = 26/262 (9%)

Query: 76   KERDLFFELDAMDHLESFIAECDRRTELAKKRLAETQEEISAEVSAKAEKVHELNEEIGK 135
            ++RD  F  +     E    +  R+    K RL E +     +     E   +L  + G+
Sbjct: 1551 QDRDRKFREEEQLRQEREEQQLSRQERDRKFRLEEQKVRRQEQERKFMEDEQQLRRQEGQ 1610

Query: 136  LLAKAEQLGAEGNVDESQKILMEVEKVRAKKKEAEEEYRNSMPASSFQQQKLRVCEVCSA 195
               + E+   +    E +++L E E+ +  ++E + ++    P    Q+++ ++      
Sbjct: 1611 QQLRQER---DRKFREDEQLLQEREEQQLHRQERDRKFLEEEPQLRRQEREQQL------ 1661

Query: 196  YLGLHDNDRRLADHFGGKLHLGFIQIREKLDQLRKTVAEKQEKRNQDRLR---------R 246
                HD DR+  +     L  G  Q   + ++ RK   E+Q+ R Q+R R         R
Sbjct: 1662 ---RHDRDRKFREE-EQLLQEGEEQQLRRQERDRKFREEEQQLRRQERERKFLQEEQQLR 1717

Query: 247  REERE---REERLSRRSGSRTRDRRRSRSRDRRRRRSRSTSRERRKLSRSRSRDRHRRHR 303
            R+E E   REE   R+   + + RR+ R R           RE ++L R + RDR  R  
Sbjct: 1718 RQELERKFREEEQLRQETEQEQLRRQERYRKILEEEQLRPEREEQQL-RRQERDRKFREE 1776

Query: 304  SRSRSHSRGHRRASRDRSAKYK 325
             + R      +  S++   K++
Sbjct: 1777 EQLRQEREEQQLRSQESDRKFR 1798



 Score = 46.2 bits (108), Expect = 4e-05
 Identities = 45/206 (21%), Positives = 89/206 (43%), Gaps = 24/206 (11%)

Query: 100  RTELAKKRLAETQEEISAEVSAKAEKVHELNEE--IGKLLAKAEQLGAEGNVDESQKILM 157
            R E  K+RL E + +   E   + E+   L EE    +      Q   E  + + ++ L+
Sbjct: 1035 REEREKRRLQERERQYREEEELQQEEEQLLGEERETRRRQELERQYRKEEELQQEEEQLL 1094

Query: 158  EVEKVRAKKKEAEEEYRNSMPASSFQQQKLRVCEVCSAYLGLHDNDRRLADHFGGKLHLG 217
              E  + +++E E + R        ++Q LR            + ++R       + +  
Sbjct: 1095 REEPEKRRRQERERQCREEEELQQEEEQLLR-----------EEREKRRRQELE-RQYRE 1142

Query: 218  FIQIREKLDQLRKTVAEKQEKRNQDRLRRREE--REREERLSRRSGSRTRDRRRSRSRDR 275
              +++++ +QL +   EK+ ++  +R  R EE  ++ EE+L R         +R + R+R
Sbjct: 1143 EEEVQQEEEQLLREEPEKRRRQELERQYREEEELQQEEEQLLRE-----EQEKRRQERER 1197

Query: 276  RRRRSRSTSRERRKLSRSRSRDRHRR 301
            + R      R++RK    R RD  +R
Sbjct: 1198 QYREEEELQRQKRK---QRYRDEDQR 1220



 Score = 46.2 bits (108), Expect = 4e-05
 Identities = 54/232 (23%), Positives = 100/232 (43%), Gaps = 37/232 (15%)

Query: 100  RTELAKKRLAETQEEISAEVSAKAEKVHELNEEIGKLLAKAEQLGAEGNVDESQKILMEV 159
            R E  K+R  E + +   E   + E+   L EE  K   + E+   E           E+
Sbjct: 1155 REEPEKRRRQELERQYREEEELQQEEEQLLREEQEKRRQERERQYREEE---------EL 1205

Query: 160  EKVRAKKKEAEEEYRNSMPASSFQQQKLRVCEVCSAYLGLHDND--RRLADHFGGKLHLG 217
            ++ + K++  +E+ R+ +    ++ +K         Y    +N+  R+L D         
Sbjct: 1206 QRQKRKQRYRDEDQRSDLKWQ-WEPEKENAVRDNKVYCKGRENEQFRQLEDS-------- 1256

Query: 218  FIQIREKLDQ--LRKTVAEKQEKRNQDRLRRREERER----EERLSRRSGSRTRDRRRSR 271
              Q+R++  Q  L+  + E+QE+  +   RR ++R+R    EE+L R       +++ ++
Sbjct: 1257 --QLRDRQSQQDLQHLLGEQQERDREQERRRWQQRDRHFPEEEQLER------EEQKEAK 1308

Query: 272  SRDRRRRRSRSTSRERRKLSRSRSR-DRHRRHRSR--SRSHSRGHRRASRDR 320
             RDR+ +  +   RE R+  R R   DR  R   +       +  RR  RDR
Sbjct: 1309 RRDRKSQEEKQLLREEREEKRRRQETDRKFREEEQLLQEREEQPLRRQERDR 1360



 Score = 45.8 bits (107), Expect = 5e-05
 Identities = 47/234 (20%), Positives = 92/234 (39%), Gaps = 31/234 (13%)

Query: 100  RTELAKKRLAETQEEISAEVSAKAEKVHELNEEIGK--LLAKAEQLGAEGNVDESQKILM 157
            R E  K+R  E + +   +   + E+   L EE  K  L  +  Q   E  + + ++ L+
Sbjct: 1005 REEREKRRRQEWERQYRKKDELQQEEEQLLREEREKRRLQERERQYREEEELQQEEEQLL 1064

Query: 158  EVEKVRAKKKEAEEEYRNSMPASSFQQQKLRVCEVCSAYLGLHDNDRRLADHFGGKLHLG 217
              E+   +++E E +YR        ++Q LR            + ++R            
Sbjct: 1065 GEERETRRRQELERQYRKEEELQQEEEQLLR-----------EEPEKRRR---------- 1103

Query: 218  FIQIREKLDQLRKTVAEKQEK--RNQDRLRRREEREREERLSRRSGSRTRDRRRSRSRDR 275
              Q RE+  +  + + +++E+  R +   RRR+E ER+ R             R     R
Sbjct: 1104 --QERERQCREEEELQQEEEQLLREEREKRRRQELERQYREEEEVQQEEEQLLREEPEKR 1161

Query: 276  RRRRSRSTSRERRKLSRSRSR----DRHRRHRSRSRSHSRGHRRASRDRSAKYK 325
            RR+      RE  +L +   +    ++ +R + R R +        + R  +Y+
Sbjct: 1162 RRQELERQYREEEELQQEEEQLLREEQEKRRQERERQYREEEELQRQKRKQRYR 1215



 Score = 44.7 bits (104), Expect = 1e-04
 Identities = 49/226 (21%), Positives = 94/226 (41%), Gaps = 24/226 (10%)

Query: 99   RRTELAKKRLAETQEEISAEVSAKAEKVHELNEEIGKLLAKAEQLGAEGNVDESQKILME 158
            RR E  +K L E Q+    E+  K  +  +L +E      + EQL  +    E  + ++E
Sbjct: 1701 RRQERERKFLQEEQQLRRQELERKFREEEQLRQE-----TEQEQLRRQ----ERYRKILE 1751

Query: 159  VEKVRAKKKEAEEEYRNSMPASSFQQQKLRVCEVCSAYLGLHDNDRRLADHFGGKLHLGF 218
             E++R +++E  ++ R       F++++    E     L   ++DR+  +    +     
Sbjct: 1752 EEQLRPEREE--QQLRRQERDRKFREEEQLRQEREEQQLRSQESDRKFREEEQLRQEREE 1809

Query: 219  IQIREKL---------DQLRKTVAEKQEKRNQDRLRRREEREREERLSRRSGSRTRDRRR 269
             Q+R +          +QL+    E++ ++ +DR  R EE+   +  SRR          
Sbjct: 1810 QQLRPQQRDGKYRWEEEQLQLEEQEQRLRQERDRQYRAEEQFATQEKSRREEQELWQEEE 1869

Query: 270  SRSRDRRRRRSRSTSRERRKLSRSRSRDRHRRHRSRSRSHSRGHRR 315
             + R  R R+ R     R++    +   RHR+         +GH R
Sbjct: 1870 QKRRQERERKLREEHIRRQQ----KEEQRHRQVGEIKSQEGKGHGR 1911



 Score = 43.9 bits (102), Expect = 2e-04
 Identities = 49/228 (21%), Positives = 86/228 (37%), Gaps = 46/228 (20%)

Query: 99   RRTELAKKRLAETQEEISAEVSAKAEKVHELNEEIGKLLAKAEQ---LGAEGNVDESQKI 155
            R T  AK  L   QE++  E     E+  EL  E  +   + EQ      E  + + ++ 
Sbjct: 886  RHTLYAKPAL---QEQLRKEQQLLQEEEEELQREEREKRRRQEQERQYREEEQLQQEEEQ 942

Query: 156  LMEVEKVRAKKKEAEEEYRNSMPASSFQQQKLRVCEVCSAYLGLHDNDRRLADHFGGKLH 215
            L+  E+ + +++E E +YR        ++Q L                            
Sbjct: 943  LLREEREKRRRQERERQYRKDKKLQQKEEQLLG--------------------------- 975

Query: 216  LGFIQIREKLDQLRKTVAEKQEKRNQDRLRRREEREREERLSRRSGSRTRDRRRSRSRDR 275
                   E+ ++ R+   EK+ +  ++  +  E+  REER  RR   R    R+ R +D 
Sbjct: 976  -------EEPEKRRRQEREKKYREEEELQQEEEQLLREEREKRR---RQEWERQYRKKDE 1025

Query: 276  RRRRSRSTSRERRKLSRSRSRDRHRRHRSRSRSHSR---GHRRASRDR 320
             ++      RE R+  R + R+R  R     +       G  R +R R
Sbjct: 1026 LQQEEEQLLREEREKRRLQERERQYREEEELQQEEEQLLGEERETRRR 1073



 Score = 43.9 bits (102), Expect = 2e-04
 Identities = 58/264 (21%), Positives = 114/264 (43%), Gaps = 35/264 (13%)

Query: 68   RADYEIASKERDLFFELDAMDHLES---FIAECDR--RTELAKKRLAETQEEISAEVSAK 122
            R +  +  +ERD  F  + + H E    F+ E  R  R E  +K L E Q+         
Sbjct: 1348 REEQPLRRQERDRKFREEELRHQEQGRKFLEEEQRLRRQERERKFLKEEQQ------LRC 1401

Query: 123  AEKVHELNEEIGKLLAKAEQLGAEGNVDESQKILMEVEKVRAKKKEAEEEYRNSMPASSF 182
             E+  +L ++  +   + EQ  +    D  +K   E ++VR  ++E E ++         
Sbjct: 1402 QEREQQLRQDRDRKFREEEQQLSRQERD--RKFREEEQQVR--RQERERKFLE------- 1450

Query: 183  QQQKLRVCEVCSAYLGLHDNDRRLADHFGGKLHLGFIQIREKLDQLRKTVAEKQEKRNQD 242
            ++Q+LR       +    + ++ L +    +LH      R++ D  RK + E+Q+ R Q+
Sbjct: 1451 EEQQLRQ----ERHRKFREEEQLLQEREEQQLH------RQERD--RKFLEEEQQLRRQE 1498

Query: 243  RLRR-REEREREERLSRRSGSRTRDRRRSRSRDRRRRRSRSTSRERRKLSRSRSRDRHRR 301
            R R+ RE+  R +   R+     +   R + + +  +  +   R+ R   R + RDR  R
Sbjct: 1499 RDRKFREQELRSQEPERKFLEEEQQLHRQQRQRKFLQEEQQLRRQERGQQRRQDRDRKFR 1558

Query: 302  HRSRSRSHSRGHRRASRDRSAKYK 325
               + R      + + ++R  K++
Sbjct: 1559 EEEQLRQEREEQQLSRQERDRKFR 1582



 Score = 43.5 bits (101), Expect = 3e-04
 Identities = 47/202 (23%), Positives = 86/202 (42%), Gaps = 19/202 (9%)

Query: 139 KAEQLGAEGNVDESQKILMEVEKV---RAKKKEAEEEYRNSMPASSFQQQKLRVCEVCSA 195
           +  QL AE      Q+ L E E+    R +++E E+E +        Q+++ R  ++   
Sbjct: 794 RERQLRAEERQQREQRFLPEEEEKEQRRRQRREREKELQFLEEEEQLQRRE-RAQQLQEE 852

Query: 196 YLGLHDNDRRLADHFGGKLHLGFIQIREKLDQLRKTVAEK----QEKRNQDRLRRREERE 251
             GL ++  R       +      Q+ E+  + R T+  K    ++ R + +L + EE E
Sbjct: 853 EDGLQEDQERRRSQEQRRDQKWRWQLEEERKRRRHTLYAKPALQEQLRKEQQLLQEEEEE 912

Query: 252 --REERLSRRSGSRTRDRRRSRSRDRRRRRSRSTSRERRKLSRSRSRDRHRRHRSRSRSH 309
             REER  RR   R    R+ R  ++ ++      RE R+  R + R+R  R   + +  
Sbjct: 913 LQREEREKRR---RQEQERQYREEEQLQQEEEQLLREEREKRRRQERERQYRKDKKLQQK 969

Query: 310 ------SRGHRRASRDRSAKYK 325
                     +R  ++R  KY+
Sbjct: 970 EEQLLGEEPEKRRRQEREKKYR 991



 Score = 43.5 bits (101), Expect = 3e-04
 Identities = 43/206 (20%), Positives = 87/206 (42%), Gaps = 16/206 (7%)

Query: 102  ELAKKRLAETQEEISAEVSAKAEKVHELNEEIGKLLAKA--EQLGAEGNVDESQKILMEV 159
            E  K+R  E +++   E   + E+   L EE  K   +    Q   +  + + ++ L+  
Sbjct: 977  EPEKRRRQEREKKYREEEELQQEEEQLLREEREKRRRQEWERQYRKKDELQQEEEQLLRE 1036

Query: 160  EKVRAKKKEAEEEYRNSMPASSFQQQKLRVCEVCSAYLGLHDNDRRLADHFGGKLHLGFI 219
            E+ + + +E E +YR        ++Q           LG     RR  +    + +    
Sbjct: 1037 EREKRRLQERERQYREEEELQQEEEQ----------LLGEERETRRRQEL--ERQYRKEE 1084

Query: 220  QIREKLDQLRKTVAEKQEKRNQDRLRRREEREREERLSRRSGSRTRDRRRSRSRDRRRRR 279
            +++++ +QL +   EK  +R Q+R R+  E E  ++   +     R++RR +  +R+ R 
Sbjct: 1085 ELQQEEEQLLREEPEK--RRRQERERQCREEEELQQEEEQLLREEREKRRRQELERQYRE 1142

Query: 280  SRSTSRERRKLSRSRSRDRHRRHRSR 305
                 +E  +L R     R R+   R
Sbjct: 1143 EEEVQQEEEQLLREEPEKRRRQELER 1168



 Score = 43.5 bits (101), Expect = 3e-04
 Identities = 54/253 (21%), Positives = 109/253 (43%), Gaps = 49/253 (19%)

Query: 99   RRTELAKKRLAETQEEISAEVSAKAEKVHELN----EEIGKLLAKAEQLGAEGNVDESQK 154
            R+ E ++ R  ++Q+++   +  + E+  E      ++  +   + EQL  E   +  ++
Sbjct: 1251 RQLEDSQLRDRQSQQDLQHLLGEQQERDREQERRRWQQRDRHFPEEEQLEREEQKEAKRR 1310

Query: 155  ILMEVEKVRAKKKEAEEEYRNSMPASSFQQQKLRVCEVCSAYLGLHDNDRRLADHFGGKL 214
                 E+ +  ++E EE+ R       F++++  + E     L   + DR+  +      
Sbjct: 1311 DRKSQEEKQLLREEREEKRRRQETDRKFREEEQLLQEREEQPLRRQERDRKFREE----- 1365

Query: 215  HLGFIQIREKLDQLRKTVAEKQEKRNQDRLRRREE-------------REREERLSRRSG 261
                 ++R + +Q RK + E+Q      RLRR+E              +ERE++L +   
Sbjct: 1366 -----ELRHQ-EQGRKFLEEEQ------RLRRQERERKFLKEEQQLRCQEREQQLRQDRD 1413

Query: 262  SRTRDRRRSRSRDRRRRRSRSTSRERRKLSRSRS---------RDRHRRHRS-----RSR 307
             + R+  +  SR  R R+ R   ++ R+  R R          ++RHR+ R      + R
Sbjct: 1414 RKFREEEQQLSRQERDRKFREEEQQVRRQERERKFLEEEQQLRQERHRKFREEEQLLQER 1473

Query: 308  SHSRGHRRASRDR 320
               + HR+  RDR
Sbjct: 1474 EEQQLHRQ-ERDR 1485



 Score = 42.7 bits (99), Expect = 4e-04
 Identities = 49/240 (20%), Positives = 104/240 (43%), Gaps = 10/240 (4%)

Query: 69  ADYEIASKERDLFFELDAMDHLESFIAECDRRTELAKKRLAETQEEISAEVSAKAEKVHE 128
           A+ E  S++++   + D     E    +     E  ++R  E Q +     S K  +  E
Sbjct: 149 AEGEEQSEKQERLEQRDRQRRDEELWRQRQEWQEREERRAEEEQLQ-----SCKGHETEE 203

Query: 129 LNEEIGKLLAKAEQLGAEGNVDESQKILMEVEKVRAKKKEAEEEYRNSMPASSFQQQKLR 188
             +E      +  +L  +G  ++ Q+      + R  ++E E+E+R        +++KL+
Sbjct: 204 FPDEEQLRRRELLELRRKGREEKQQQ--RRERQDRVFQEEEEKEWRKRETVLRKEEEKLQ 261

Query: 189 VCEVCSAYLGLHDNDRRLADHFGGKLHLGFIQIREKLDQLRKTVAEKQEKRNQDRLRRRE 248
             E       L + + +L      +L     +  ++  +LR+   + + K+ ++R  ++E
Sbjct: 262 E-EEPQRQRELQEEEEQLRKLERQELRRERQEEEQQQQRLRRE-QQLRRKQEEERREQQE 319

Query: 249 E-REREERLSRRSGSRTRDRRRSRSRDRRRRRSRSTSRERRKLSRSRSRDRHRRHRSRSR 307
           E RE++ER  ++   R +  RR +   R ++  R    ERR+    R ++  RR +   R
Sbjct: 320 ERREQQERREQQEERREQQLRREQEERREQQLRREQEEERREQQLRREQEEERREQQLRR 379



 Score = 42.7 bits (99), Expect = 4e-04
 Identities = 55/234 (23%), Positives = 97/234 (41%), Gaps = 19/234 (8%)

Query: 100  RTELAKKRLAETQEEISAEVSAK-AEKVHELNEEIGKLLAKAEQLGAEGNVDESQKILME 158
            R E  +K L E Q+    E   K  E+     E   K L + +QL  +      +K L E
Sbjct: 1480 RQERDRKFLEEEQQLRRQERDRKFREQELRSQEPERKFLEEEQQLHRQ---QRQRKFLQE 1536

Query: 159  VEKVRAKKKEAEEEYRNSMPASSFQQQKLRVCEVCSAYLGLHDNDRRLA-DHFGGKLHLG 217
             +++R  ++E  ++ R        ++++LR  E     L   + DR+   +    +    
Sbjct: 1537 EQQLR--RQERGQQRRQDRDRKFREEEQLRQ-EREEQQLSRQERDRKFRLEEQKVRRQEQ 1593

Query: 218  FIQIREKLDQLRKTVAEKQEKRNQDRLRRREEREREERLSRRSGSRTRD----------R 267
              +  E   QLR+   ++Q ++ +DR  R +E+  +ER  ++   + RD          R
Sbjct: 1594 ERKFMEDEQQLRRQEGQQQLRQERDRKFREDEQLLQEREEQQLHRQERDRKFLEEEPQLR 1653

Query: 268  RRSRSRDRRRRRSRSTSRERRKLSRSRSRDRHRRHRSRS-RSHSRGHRRASRDR 320
            R+ R +  R  R R    E + L     +   R+ R R  R   +  RR  R+R
Sbjct: 1654 RQEREQQLRHDRDRKFREEEQLLQEGEEQQLRRQERDRKFREEEQQLRRQERER 1707



 Score = 41.2 bits (95), Expect = 0.001
 Identities = 51/236 (21%), Positives = 97/236 (41%), Gaps = 25/236 (10%)

Query: 96   ECDRRTELAKKRLAETQEEISAEVSAKAEKVHELNEEIGKLLA-----KAEQLGAEGNVD 150
            E +RR    + R    +E++  E   +A++    ++E  +LL      K  +   +    
Sbjct: 1280 EQERRRWQQRDRHFPEEEQLEREEQKEAKRRDRKSQEEKQLLREEREEKRRRQETDRKFR 1339

Query: 151  ESQKILMEVEKVRAKKKEA-----EEEYRNSMPASSFQQQKLRVCEVCSAYLGLHDNDRR 205
            E +++L E E+   +++E      EEE R+      F +++ R        L   + +R+
Sbjct: 1340 EEEQLLQEREEQPLRRQERDRKFREEELRHQEQGRKFLEEEQR--------LRRQERERK 1391

Query: 206  LADHFGGKLHLGFIQIREKLDQLRKTVAEKQEKRNQDRLRRREEREREERLSRRSGSRTR 265
                   +L     + + + D+ RK   E+Q+   Q+R R+  E E++ R   R      
Sbjct: 1392 FLKE-EQQLRCQEREQQLRQDRDRKFREEEQQLSRQERDRKFREEEQQVRRQERERKFLE 1450

Query: 266  DRRRSRSRDRRRRRSRSTSRERRKLSRSRSRDRHRRHRSRS-RSHSRGHRRASRDR 320
            + ++      R+ R R    E + L     +  HR+ R R      +  RR  RDR
Sbjct: 1451 EEQQ-----LRQERHRKFREEEQLLQEREEQQLHRQERDRKFLEEEQQLRRQERDR 1501



 Score = 40.8 bits (94), Expect = 0.002
 Identities = 47/233 (20%), Positives = 84/233 (36%), Gaps = 30/233 (12%)

Query: 98  DRRTELAKKRLAETQEEISAEVSAKAEKVHELNEEIGKLLAKAE-QLGAEGNVDESQKIL 156
           +   E  ++RL    EE   E     E+  +  E I   + K + QL +E +  +S K+ 
Sbjct: 662 EEEEERLEQRLKREHEEERREQELAEEEQEQARERIKSRIPKWQWQLESEADARQS-KVY 720

Query: 157 MEVEKVRAKKKEAEEEYRNSMPASSFQQQKLRVCEVCSAYLGLHDNDRRLADHFGGKLHL 216
               K   +++  E+E +     S  Q Q+                          + H 
Sbjct: 721 SRPRKQEGQRRRQEQEEKRRRRESELQWQEEE------------------------RAHR 756

Query: 217 GFIQIREKLDQLRKTVAEKQEKRNQDRLRRR----EEREREERLSRRSGSRTRDRRRSRS 272
              +  ++ D   +  AE++ +R + RL  R    E+RER+ R   R     R       
Sbjct: 757 QQQEEEQRRDFTWQWQAEEKSERGRQRLSARPPLREQRERQLRAEERQQREQRFLPEEEE 816

Query: 273 RDRRRRRSRSTSRERRKLSRSRSRDRHRRHRSRSRSHSRGHRRASRDRSAKYK 325
           +++RRR+ R   +E + L       R  R +              R RS + +
Sbjct: 817 KEQRRRQRREREKELQFLEEEEQLQRRERAQQLQEEEDGLQEDQERRRSQEQR 869



 Score = 40.4 bits (93), Expect = 0.002
 Identities = 28/103 (27%), Positives = 47/103 (45%), Gaps = 12/103 (11%)

Query: 225 LDQLRKTVAEKQEKRNQDRLRRREERE---REERLSRRSGSRTRDRRRSRSRDRRRRRSR 281
           LD+ ++   + +E   QDR +  ++R    R+ +L    G R R +R+ + R+      +
Sbjct: 95  LDEEKRARCDGKESLLQDRRQEEDQRRFEPRDRQLEEEPGQRRRQKRQEQERELAEGEEQ 154

Query: 282 STSRERRKLSRSRSRDRHRRH----RSRSRSHSRGHRRASRDR 320
           S  +ER +      RDR RR     R R     R  RRA  ++
Sbjct: 155 SEKQERLE-----QRDRQRRDEELWRQRQEWQEREERRAEEEQ 192



 Score = 39.3 bits (90), Expect = 0.005
 Identities = 25/104 (24%), Positives = 48/104 (46%), Gaps = 1/104 (0%)

Query: 222  REKLDQLRKTVAEKQEKRNQDRLRRREEREREERLSRRSGSRTRDRRRSRSRDRRRRRSR 281
            +E+   LR+   EK+ ++  DR  R EE+  +ER  +    + RDR+      R + + R
Sbjct: 1315 QEEKQLLREEREEKRRRQETDRKFREEEQLLQEREEQPLRRQERDRKFREEELRHQEQGR 1374

Query: 282  STSRERRKLSRSRSRDRHRRHRSRSRSHSRGHRRASRDRSAKYK 325
                E ++L R     +  +   + R   R  ++  +DR  K++
Sbjct: 1375 KFLEEEQRLRRQERERKFLKEEQQLRCQER-EQQLRQDRDRKFR 1417



 Score = 38.5 bits (88), Expect = 0.008
 Identities = 21/106 (19%), Positives = 50/106 (47%), Gaps = 3/106 (2%)

Query: 221  IREKLDQLRKTVAEKQEKRNQDRLRRREEREREERLSRRSGSRTRDRRRSRSRDRRRRRS 280
            ++E+ ++L++   EK+ ++ Q+R  R EE+ ++E        R + RR+ R R  R+ + 
Sbjct: 906  LQEEEEELQREEREKRRRQEQERQYREEEQLQQEEEQLLREEREKRRRQERERQYRKDKK 965

Query: 281  RSTSRER---RKLSRSRSRDRHRRHRSRSRSHSRGHRRASRDRSAK 323
                 E+    +  + R ++R +++R          +    +R  +
Sbjct: 966  LQQKEEQLLGEEPEKRRRQEREKKYREEEELQQEEEQLLREEREKR 1011



 Score = 37.7 bits (86), Expect = 0.014
 Identities = 51/262 (19%), Positives = 102/262 (38%), Gaps = 58/262 (22%)

Query: 96   ECDRRTELAKKRLAETQEEISAEVSAKAEKVHELNEEIGKLLAKAEQLGAEGNVDESQKI 155
            E ++R    ++R  E Q     E   + E+  +L EE             E  + E Q+ 
Sbjct: 816  EKEQRRRQRREREKELQFLEEEEQLQRRERAQQLQEE-------------EDGLQEDQER 862

Query: 156  LMEVEKVRAKK-----KEAEEEYRNSMPASSFQQQKLRVCEVCSAYLGLHDNDRRLADHF 210
                E+ R +K     +E  +  R+++ A    Q++LR              +++L    
Sbjct: 863  RRSQEQRRDQKWRWQLEEERKRRRHTLYAKPALQEQLR-------------KEQQLLQEE 909

Query: 211  GGKLHLGFIQIREKLDQLRKTVAEKQEKRNQDRL-------RRREEREREERLSRRSGSR 263
              +L     + R + +Q R+   E+Q ++ +++L       RRR+ERER+ R  ++   +
Sbjct: 910  EEELQREEREKRRRQEQERQYREEEQLQQEEEQLLREEREKRRRQERERQYRKDKKLQQK 969

Query: 264  TR-------DRRRSRSRDRRRRRSRSTSRERRKLSRSRSRDRHRRHRSRSRS-------- 308
                     ++RR + R+++ R      +E  +L R     R R+   R           
Sbjct: 970  EEQLLGEEPEKRRRQEREKKYREEEELQQEEEQLLREEREKRRRQEWERQYRKKDELQQE 1029

Query: 309  -----HSRGHRRASRDRSAKYK 325
                      +R  ++R  +Y+
Sbjct: 1030 EEQLLREEREKRRLQERERQYR 1051



 Score = 37.7 bits (86), Expect = 0.014
 Identities = 55/251 (21%), Positives = 103/251 (41%), Gaps = 32/251 (12%)

Query: 70   DYEIASKERDLFF-----ELDAMDHLESFIAECD--RRTELAKKRLAETQ--EEISAEVS 120
            + ++  +ERD  F     +L   +    F+ E    RR EL +K   E Q  +E   E  
Sbjct: 1681 EQQLRRQERDRKFREEEQQLRRQERERKFLQEEQQLRRQELERKFREEEQLRQETEQEQL 1740

Query: 121  AKAEKVHELNEEIGKLLAKAEQLGAEGNVD----ESQKILMEVEKVRAKKKEAEEEYRNS 176
             + E+  ++ EE      + EQ       D    E +++  E E+ + + +E++ ++R  
Sbjct: 1741 RRQERYRKILEEEQLRPEREEQQLRRQERDRKFREEEQLRQEREEQQLRSQESDRKFREE 1800

Query: 177  MPA-SSFQQQKLRVCEVCSAY------LGLHDNDRRLADHFGGKLHLGFIQIREKLDQLR 229
                   ++Q+LR  +    Y      L L + ++RL      +      +  E+     
Sbjct: 1801 EQLRQEREEQQLRPQQRDGKYRWEEEQLQLEEQEQRLRQERDRQY-----RAEEQFATQE 1855

Query: 230  KTVAEKQEKRNQDRLRRREEREREERLSRRSGSRTRDRRRSRSRDRRRRRSRSTSRERRK 289
            K+  E+QE   ++  +RR+ERER+ R           RR+ +   R R+     S+E + 
Sbjct: 1856 KSRREEQELWQEEEQKRRQERERKLR-------EEHIRRQQKEEQRHRQVGEIKSQEGKG 1908

Query: 290  LSRSRSRDRHR 300
              R      H+
Sbjct: 1909 HGRLLEPGTHQ 1919



 Score = 35.4 bits (80), Expect = 0.070
 Identities = 25/99 (25%), Positives = 45/99 (45%), Gaps = 9/99 (9%)

Query: 222 REKLDQLRKTVAEKQEK-RNQDRLRRREEREREERLSR-RSGSRTRDRRRSRSRDRRRRR 279
           R+K  +  + +AE +E+   Q+RL +R+ + R+E L R R   + R+ RR+     +  +
Sbjct: 138 RQKRQEQERELAEGEEQSEKQERLEQRDRQRRDEELWRQRQEWQEREERRAEEEQLQSCK 197

Query: 280 SRSTSR-------ERRKLSRSRSRDRHRRHRSRSRSHSR 311
              T          RR+L   R + R  + + R     R
Sbjct: 198 GHETEEFPDEEQLRRRELLELRRKGREEKQQQRRERQDR 236



 Score = 32.3 bits (72), Expect = 0.59
 Identities = 26/112 (23%), Positives = 46/112 (41%), Gaps = 6/112 (5%)

Query: 198 GLHDNDRRLADHFGGKLHLGFIQIREKLDQLRKTVAEKQEKRNQDRLRRREEREREERLS 257
           GL +  R   D   GK  L  +Q R + +  R+     ++   +   RRR++R+ +ER  
Sbjct: 94  GLDEEKRARCD---GKESL--LQDRRQEEDQRRFEPRDRQLEEEPGQRRRQKRQEQEREL 148

Query: 258 RRSGSRTRDRRRSRSRDRRRRRSRSTSRERRKLSRSRSRDRHRRHRSRSRSH 309
                ++  + R   RD R+RR     R+R++      R          + H
Sbjct: 149 AEGEEQSEKQERLEQRD-RQRRDEELWRQRQEWQEREERRAEEEQLQSCKGH 199


>gi|62460633 RNA-binding motif protein 16 [Homo sapiens]
          Length = 1271

 Score = 61.6 bits (148), Expect = 9e-10
 Identities = 36/85 (42%), Positives = 51/85 (60%), Gaps = 1/85 (1%)

Query: 241 QDRLRRREEREREERLSRRSGSRTRDRRRSRSRDRRRRRSRSTSRERRKLSRSRSRDRHR 300
           QD +      +  ++++ RS SRT  R RSRS  +RR RSRS SR+R+   RSRSR R R
Sbjct: 379 QDGVEEEVFEQEAKKVAVRSRSRTHSRSRSRSPRKRRSRSRSGSRKRKHRKRSRSRSRER 438

Query: 301 RHRSRSRSHSRGHRRASRDRSAKYK 325
           + +S SRS+S   R   R++  + K
Sbjct: 439 KRKS-SRSYSSERRAREREKERQKK 462



 Score = 58.2 bits (139), Expect = 1e-08
 Identities = 72/269 (26%), Positives = 108/269 (40%), Gaps = 30/269 (11%)

Query: 50  AGTRMDLGECTKIHDLALRADYEIASKERDLFFELDAMDHLESFIAECDRRTELAKKRLA 109
           AG  + L   T     A  A   +   E+ + F    MD  +    E    +E  KK + 
Sbjct: 227 AGLVVQLQALTAQLTAAAAAANTLTPLEQGVSFNKKLMDRFD--FGEDSEHSEEPKKEIP 284

Query: 110 ETQEEISAEVSAKAEKVHELNEEIGKLLAKAEQLGAEGNVDESQKILMEVEKVRAKKKEA 169
            +Q    +E S      H++          AEQL  +      Q++L + +  +A  +++
Sbjct: 285 ASQLSHVSE-SVNNSIFHQI----------AEQLQQQNLEHLRQQLLEQQQPQKATPQDS 333

Query: 170 EE-----EYRNSMPASSFQQQKLRVCEVCSAYLGLHDNDRRLADHFGGKLHLGFIQIREK 224
           +E     E+  S    S QQ  L         + +   D  + +   G          E 
Sbjct: 334 QEGTFGSEHSASPSQGSSQQHFLEPEVNLDDSIDIQQQDMDIDEGQDGVEE-------EV 386

Query: 225 LDQLRKTVAEKQEKRNQDRLRRREEREREERLSRRSGSRTRDRR---RSRSRDRRRRRSR 281
            +Q  K VA +   R   R R R  R+R  R   RSGSR R  R   RSRSR+R+R+ SR
Sbjct: 387 FEQEAKKVAVRSRSRTHSRSRSRSPRKRRSR--SRSGSRKRKHRKRSRSRSRERKRKSSR 444

Query: 282 STSRERRKLSRSRSRDRHRRHRSRSRSHS 310
           S S ERR   R + R +      RS++ S
Sbjct: 445 SYSSERRAREREKERQKKGLPPIRSKTLS 473


>gi|7662238 apoptotic chromatin condensation inducer 1 [Homo sapiens]
          Length = 1341

 Score = 61.2 bits (147), Expect = 1e-09
 Identities = 49/169 (28%), Positives = 78/169 (46%), Gaps = 26/169 (15%)

Query: 160  EKVRAKKKEAEEEYRNSMPASSFQQQKLRVCEVCSAYLGLHDNDRRLADHFGGKLHLGFI 219
            EK   KK++A+EE    +    F++ K      C  +L L D+                 
Sbjct: 1193 EKKSEKKEKAQEEPPAKLLDDLFRKTK---AAPCIYWLPLTDS----------------- 1232

Query: 220  QIREKLDQLRKTVAEKQEKRNQDRLRRREEREREERLSRRSGSRTRDRRRSRSRDRRRRR 279
            QI +K  +  +   E++++R +     ++ERE+E     R+    R++RR  SR+R R R
Sbjct: 1233 QIVQKEAERAERAKEREKRRKEQEEEEQKEREKEAE-RERNRQLEREKRREHSRERDRER 1291

Query: 280  SRSTSRERRKLSRSRSRDRHR---RHRSRSRSHSRGHRRAS--RDRSAK 323
             R   R+R    R R RDR R   R R  ++ HSR   R++  RDR  +
Sbjct: 1292 ERERERDRGDRDRDRERDRERGRERDRRDTKRHSRSRSRSTPVRDRGGR 1340



 Score = 48.9 bits (115), Expect = 6e-06
 Identities = 33/79 (41%), Positives = 40/79 (50%), Gaps = 2/79 (2%)

Query: 222  REK-LDQLRKTVAEKQEKRNQDRLRRRE-EREREERLSRRSGSRTRDRRRSRSRDRRRRR 279
            REK  ++ R    E++++R   R R RE ERERE     R   R RDR R R RDRR  +
Sbjct: 1263 REKEAERERNRQLEREKRREHSRERDRERERERERDRGDRDRDRERDRERGRERDRRDTK 1322

Query: 280  SRSTSRERRKLSRSRSRDR 298
              S SR R    R R   R
Sbjct: 1323 RHSRSRSRSTPVRDRGGRR 1341



 Score = 47.4 bits (111), Expect = 2e-05
 Identities = 30/85 (35%), Positives = 43/85 (50%), Gaps = 7/85 (8%)

Query: 223  EKLDQLRKTVAEKQEKRNQDRLRRRE-------EREREERLSRRSGSRTRDRRRSRSRDR 275
            E+  + R+  AE++  R  +R +RRE       ERERE    R    R R+R R R R+R
Sbjct: 1257 EEEQKEREKEAERERNRQLEREKRREHSRERDRERERERERDRGDRDRDRERDRERGRER 1316

Query: 276  RRRRSRSTSRERRKLSRSRSRDRHR 300
             RR ++  SR R + +  R R   R
Sbjct: 1317 DRRDTKRHSRSRSRSTPVRDRGGRR 1341



 Score = 43.5 bits (101), Expect = 3e-04
 Identities = 31/90 (34%), Positives = 45/90 (50%), Gaps = 13/90 (14%)

Query: 235  KQEKRNQDRLRRREEREREERLSRRSGSRTRDRRRSRSRDRRRRRSRSTSRERRKLSRSR 294
            + E+R Q+R  R +  ERE  + RR  +R+    R   RD+ R   RS         RSR
Sbjct: 1132 RAEQREQERAVREQWAEREREMERRERTRSE---REWDRDKVREGPRS---------RSR 1179

Query: 295  SRDRHRRHRSRSR-SHSRGHRRASRDRSAK 323
            SRDR R+ R++S+   S    +A  +  AK
Sbjct: 1180 SRDRRRKERAKSKEKKSEKKEKAQEEPPAK 1209



 Score = 42.4 bits (98), Expect = 6e-04
 Identities = 26/70 (37%), Positives = 36/70 (51%), Gaps = 5/70 (7%)

Query: 260 SGSRTRDRRRSRSRDRRRRRSRSTSRERRKLSRSRSRDRHRRHRSRSRSHSRGHRRA--- 316
           SGSR+    RS+ RD  + R+ +  R R K+    + +   R RSRSRS S   R++   
Sbjct: 599 SGSRSHSPLRSKQRDVAQARTHANPRGRPKMGSRSTSESRSRSRSRSRSASSNSRKSLSP 658

Query: 317 --SRDRSAKY 324
             SRD S  Y
Sbjct: 659 GVSRDSSTSY 668



 Score = 42.0 bits (97), Expect = 7e-04
 Identities = 24/74 (32%), Positives = 42/74 (56%), Gaps = 1/74 (1%)

Query: 224  KLDQLRKTVAEKQEKRNQDRLRRREEREREERLSRRSGSRTRDRRRSRSRDRRRRRSRST 283
            + +Q  +  A +++   ++R   R ER R ER   R   R   R RSRSRD RRR+ R+ 
Sbjct: 1132 RAEQREQERAVREQWAEREREMERRERTRSEREWDRDKVREGPRSRSRSRD-RRRKERAK 1190

Query: 284  SRERRKLSRSRSRD 297
            S+E++   + ++++
Sbjct: 1191 SKEKKSEKKEKAQE 1204



 Score = 37.4 bits (85), Expect = 0.018
 Identities = 39/155 (25%), Positives = 48/155 (30%), Gaps = 65/155 (41%)

Query: 229  RKTVAEKQEKRNQDRLRRREER-------------------------------------- 250
            R  V E    R++ R RRR+ER                                      
Sbjct: 1167 RDKVREGPRSRSRSRDRRRKERAKSKEKKSEKKEKAQEEPPAKLLDDLFRKTKAAPCIYW 1226

Query: 251  -------------EREERLSRRSGSRTR-------------DRRRSRSRDRRRRRSRSTS 284
                         ER ER   R   R               +R R+R  +R +RR  S  
Sbjct: 1227 LPLTDSQIVQKEAERAERAKEREKRRKEQEEEEQKEREKEAERERNRQLEREKRREHSRE 1286

Query: 285  RERRKLSRSRSRDRHRRHRSRSRSHSRGHRRASRD 319
            R+R +  R R RDR  R R R R   RG  R  RD
Sbjct: 1287 RDRER-ERERERDRGDRDRDRERDRERGRERDRRD 1320



 Score = 33.5 bits (75), Expect = 0.26
 Identities = 21/70 (30%), Positives = 38/70 (54%), Gaps = 2/70 (2%)

Query: 222  REKLDQLRKTVAEKQ-EKRNQDRLRRREEREREE-RLSRRSGSRTRDRRRSRSRDRRRRR 279
            RE+   +R+  AE++ E   ++R R   E +R++ R   RS SR+RDRRR      + ++
Sbjct: 1136 REQERAVREQWAEREREMERRERTRSEREWDRDKVREGPRSRSRSRDRRRKERAKSKEKK 1195

Query: 280  SRSTSRERRK 289
            S    + + +
Sbjct: 1196 SEKKEKAQEE 1205


>gi|6631100 natural killer-tumor recognition sequence [Homo sapiens]
          Length = 1462

 Score = 61.2 bits (147), Expect = 1e-09
 Identities = 42/110 (38%), Positives = 57/110 (51%), Gaps = 14/110 (12%)

Query: 226  DQLRKTVAEKQEKRNQDRLRRREEREREERLSRRSGSRTRDRRRSRSRDRRRRRSRSTSR 285
            D++RKT    +  RNQ+     +   R++    RS SR+R +  ++SR R R  S S SR
Sbjct: 1279 DEVRKTARLNRRPRNQESSSDEQTPSRDDDSQSRSPSRSRSKSETKSRHRTRSVSYSHSR 1338

Query: 286  ER----------RKLSRSRSRDRHRRHRSRSRSHS----RGHRRASRDRS 321
             R          R  SRSRSR  + R R+RSRS S    + HR +SR RS
Sbjct: 1339 SRSRSSTSSYRSRSYSRSRSRGWYSRGRTRSRSSSYRSYKSHRTSSRSRS 1388



 Score = 43.9 bits (102), Expect = 2e-04
 Identities = 40/115 (34%), Positives = 56/115 (48%), Gaps = 6/115 (5%)

Query: 215 HLGFIQIREKLDQLRKTVAE----KQEKRNQ-DRLRRREEREREERLSRRSGSRT-RDRR 268
           HL  IQ    L  +++T +     K+EK ++ D+    +  +R    S RS SR+ R R 
Sbjct: 642 HLLPIQSTYSLANIKETGSSSSYHKREKNSESDQSTYSKYSDRSSESSPRSRSRSSRSRS 701

Query: 269 RSRSRDRRRRRSRSTSRERRKLSRSRSRDRHRRHRSRSRSHSRGHRRASRDRSAK 323
            SRS  R R  + S SR R   SRS SR+++  H   SRS S     +   R AK
Sbjct: 702 YSRSYTRSRSLASSHSRSRSPSSRSHSRNKYSDHSQCSRSSSYTSISSDDGRRAK 756



 Score = 38.9 bits (89), Expect = 0.006
 Identities = 33/97 (34%), Positives = 44/97 (45%), Gaps = 12/97 (12%)

Query: 239  RNQDRLRRREEREREERLSRRSGSRTRDRRRSRSRDRR---------RRRSRSTSRERRK 289
            R++ R      R R    SR  G  +R R RSRS   R         R RSRS+S +   
Sbjct: 1338 RSRSRSSTSSYRSRSYSRSRSRGWYSRGRTRSRSSSYRSYKSHRTSSRSRSRSSSYDPHS 1397

Query: 290  LSRSRSRDRH---RRHRSRSRSHSRGHRRASRDRSAK 323
             SRS + D +    R RSRS+     HR  S +R ++
Sbjct: 1398 RSRSYTYDSYYSRSRSRSRSQRSDSYHRGRSYNRRSR 1434



 Score = 37.7 bits (86), Expect = 0.014
 Identities = 36/101 (35%), Positives = 49/101 (48%), Gaps = 18/101 (17%)

Query: 235 KQEKRNQDRLRRREEREREERLSRRSGSRTRDRRRSRS------------RDRRRRRSRS 282
           +  K +  R++   +RER  R S  S   +  R  S+S            RD  R +S S
Sbjct: 466 ESSKSSTRRMKSSCDRERSSRSSSLSSHHSSKRDWSKSDKDVQSSLTHSSRDSYRSKSHS 525

Query: 283 TSRERRKLSRSRSRDR---HRRHRSRSRSHSR-GHR-RASR 318
            S  R   SRSR+  +   H R RS+SRS S+ GHR RAS+
Sbjct: 526 QSYSRGS-SRSRTASKSSSHSRSRSKSRSSSKSGHRKRASK 565



 Score = 37.7 bits (86), Expect = 0.014
 Identities = 35/97 (36%), Positives = 42/97 (43%), Gaps = 17/97 (17%)

Query: 239  RNQDRLRRREERE-REERLSRRSGSRT-----RDRRRSRSRDRRRRRSRSTSRERRKLSR 292
            R + R R    R  +  R S RS SR+       R RS + D    RSRS SR +R  S 
Sbjct: 1364 RGRTRSRSSSYRSYKSHRTSSRSRSRSSSYDPHSRSRSYTYDSYYSRSRSRSRSQRSDSY 1423

Query: 293  SRSRDRHRRHRS-----------RSRSHSRGHRRASR 318
             R R  +RR RS           RS SH R    +SR
Sbjct: 1424 HRGRSYNRRSRSCRSYGSDSESDRSYSHHRSPSESSR 1460



 Score = 35.8 bits (81), Expect = 0.053
 Identities = 47/182 (25%), Positives = 78/182 (42%), Gaps = 28/182 (15%)

Query: 158 EVEKVRAKKKEAEEEYRN----SMPASS-FQQQKLRVCEVCSAYLGLHDNDRRLADHFGG 212
           E++++RA +  + E++      S P SS + ++ L       +Y G + +D   A H G 
Sbjct: 368 EMQRLRAYRPPSGEKWSKGDKLSDPCSSRWDERSLSQRSRSWSYNGYY-SDLSTARHSG- 425

Query: 213 KLHLGFIQIREKLDQLRKTVAEKQEKRNQDRLRRREEREREERLS----RRSGSRTRDRR 268
                      K  +  K V  K++ + Q   RR ++ ++   L       S S TR  +
Sbjct: 426 ---------HHKKRRKEKKVKHKKKGKKQKHCRRHKQTKKRRILIPSDIESSKSSTRRMK 476

Query: 269 RSRSRDRRRRRSRSTSRERRKLSRSRSRD-------RHRRHRSRSRSHSRGHRR-ASRDR 320
            S  R+R  R S  +S    K   S+S            R   RS+SHS+ + R +SR R
Sbjct: 477 SSCDRERSSRSSSLSSHHSSKRDWSKSDKDVQSSLTHSSRDSYRSKSHSQSYSRGSSRSR 536

Query: 321 SA 322
           +A
Sbjct: 537 TA 538



 Score = 35.8 bits (81), Expect = 0.053
 Identities = 23/52 (44%), Positives = 29/52 (55%), Gaps = 1/52 (1%)

Query: 255 RLSRRSGSRTRDRRRSRSRDRRRRRSRSTSRERRKLSRSRSRDRHRRHRSRS 306
           R S RS S ++   R  SR R   +S S SR R K SRS S+  HR+  S+S
Sbjct: 516 RDSYRSKSHSQSYSRGSSRSRTASKSSSHSRSRSK-SRSSSKSGHRKRASKS 566



 Score = 34.3 bits (77), Expect = 0.16
 Identities = 27/78 (34%), Positives = 40/78 (51%), Gaps = 12/78 (15%)

Query: 259  RSGSRTRDRRRSRSRDRRRRRSRSTSRER----------RKLSRSRSRDRHR-RHRSRSR 307
            R GS   + R++   +RR R   S+S E+          R  SRSRS+   + RHR+RS 
Sbjct: 1273 RPGSLFDEVRKTARLNRRPRNQESSSDEQTPSRDDDSQSRSPSRSRSKSETKSRHRTRSV 1332

Query: 308  SHSRGHRRASRDRSAKYK 325
            S+S    R SR  ++ Y+
Sbjct: 1333 SYSHSRSR-SRSSTSSYR 1349



 Score = 33.9 bits (76), Expect = 0.20
 Identities = 29/97 (29%), Positives = 45/97 (46%), Gaps = 6/97 (6%)

Query: 231 TVAEKQEKRNQDRLRRREEREREER--LSRRSGSRTRDRRRSRSRDRRRRR-SRSTSRER 287
           ++A  +E  +     +RE+    ++   S+ S   +    RSRSR  R R  SRS +R R
Sbjct: 651 SLANIKETGSSSSYHKREKNSESDQSTYSKYSDRSSESSPRSRSRSSRSRSYSRSYTRSR 710

Query: 288 RKLSRSRSRDRHRRHRSRSRSHSRGHRRASRDRSAKY 324
              S + S  R R   SRS S ++    +   RS+ Y
Sbjct: 711 ---SLASSHSRSRSPSSRSHSRNKYSDHSQCSRSSSY 744



 Score = 33.5 bits (75), Expect = 0.26
 Identities = 30/87 (34%), Positives = 38/87 (43%), Gaps = 6/87 (6%)

Query: 240  NQDRLRRREEREREERLSRRSGSRTRDRR-----RSRSRDRRRRRSRSTSRERRKLSRSR 294
            ++ R R R    R  + S R+ SR+R R       SRSR        S SR R +  RS 
Sbjct: 1363 SRGRTRSRSSSYRSYK-SHRTSSRSRSRSSSYDPHSRSRSYTYDSYYSRSRSRSRSQRSD 1421

Query: 295  SRDRHRRHRSRSRSHSRGHRRASRDRS 321
            S  R R +  RSRS       +  DRS
Sbjct: 1422 SYHRGRSYNRRSRSCRSYGSDSESDRS 1448



 Score = 30.4 bits (67), Expect = 2.2
 Identities = 23/103 (22%), Positives = 37/103 (35%), Gaps = 7/103 (6%)

Query: 221 IREKLDQLRKTVAEKQEKRNQDRLRRREEREREERLSRRSGSRTRDRRRSRSRDRRRRRS 280
           I++  ++ RK     +   +        E   E  L         +R R R   RR +  
Sbjct: 181 IKDVFEKKRKKPTHSEGSDSSSNSSSSSESSSESELEH-------ERSRRRKHKRRPKVK 233

Query: 281 RSTSRERRKLSRSRSRDRHRRHRSRSRSHSRGHRRASRDRSAK 323
           RS  R +   S    R++H  +       S  + + S D SAK
Sbjct: 234 RSKKRRKEASSSEEPRNKHAMNPKGHSERSDTNEKRSVDSSAK 276



 Score = 29.6 bits (65), Expect = 3.8
 Identities = 18/62 (29%), Positives = 28/62 (45%)

Query: 230 KTVAEKQEKRNQDRLRRREEREREERLSRRSGSRTRDRRRSRSRDRRRRRSRSTSRERRK 289
           K V       ++D  R +   +   R S RS + ++    SRSR + R  S+S  R+R  
Sbjct: 505 KDVQSSLTHSSRDSYRSKSHSQSYSRGSSRSRTASKSSSHSRSRSKSRSSSKSGHRKRAS 564

Query: 290 LS 291
            S
Sbjct: 565 KS 566



 Score = 28.9 bits (63), Expect = 6.5
 Identities = 23/84 (27%), Positives = 38/84 (45%), Gaps = 6/84 (7%)

Query: 220 QIREKLDQLRKTVAEKQEKRNQDRLRRREEREREERLSRRSGSRTRDRRRSRSRDRRRR- 278
           Q +EK  Q+ +T   KQEK N+   + + ERE      R       D  R+ S+ +R+  
Sbjct: 823 QEKEKQGQMERT-HNKQEK-NRGEEKSKSERECPHSKKRTLKENLSDHLRNGSKPKRKNY 880

Query: 279 ---RSRSTSRERRKLSRSRSRDRH 299
              +  S S   R ++++   D H
Sbjct: 881 AGSKWDSESNSERDVTKNSKNDSH 904


>gi|119226260 calcium homeostasis endoplasmic reticulum protein
           [Homo sapiens]
          Length = 916

 Score = 60.8 bits (146), Expect = 2e-09
 Identities = 45/105 (42%), Positives = 53/105 (50%), Gaps = 17/105 (16%)

Query: 227 QLRKTVAEKQEKRNQDRLRRREEREREERLSRRSGSRT----------RDRRRSRSRDRR 276
           ++R    + QEKRN    R R   +   R S RS SR+          R R  SRS  R 
Sbjct: 720 KMRARRRKGQEKRNSGPSRSRSRSKSRGRSSSRSNSRSSKSSGSYSRSRSRSCSRSYSRS 779

Query: 277 RRRSRSTSRERRKLSRSRSRDRHRRHRSRSRSHSRGHRRASRDRS 321
           R RSRS SR  R  SRS+S       RSRS+S+S G RR SR RS
Sbjct: 780 RSRSRSRSRSSRSRSRSQS-------RSRSKSYSPGRRRRSRSRS 817



 Score = 52.8 bits (125), Expect = 4e-07
 Identities = 41/89 (46%), Positives = 48/89 (53%), Gaps = 4/89 (4%)

Query: 239 RNQDRLRRREEREREERLSRRSGSRTRDRRRSRSRDRRR--RRSRSTSRER-RKLSRSRS 295
           R + R RRR+ +E+      RS SR++ R RS SR   R  + S S SR R R  SRS S
Sbjct: 718 RAKMRARRRKGQEKRNSGPSRSRSRSKSRGRSSSRSNSRSSKSSGSYSRSRSRSCSRSYS 777

Query: 296 RDRHRRHRSRSRSHSRGHRRASRDRSAKY 324
           R R R  RSRSRS     R  SR RS  Y
Sbjct: 778 RSRSRS-RSRSRSSRSRSRSQSRSRSKSY 805



 Score = 35.4 bits (80), Expect = 0.070
 Identities = 35/95 (36%), Positives = 42/95 (44%), Gaps = 22/95 (23%)

Query: 249 EREREERLSRRSGSRTRDRRRSRSRDRR----------RRRSRSTSRER---------RK 289
           +R R      ++G     R + R+R R+          R RSRS SR R          K
Sbjct: 700 DRPRNSEGWEQNGLYEFFRAKMRARRRKGQEKRNSGPSRSRSRSKSRGRSSSRSNSRSSK 759

Query: 290 LSRSRSRDRHR---RHRSRSRSHSRGHRRASRDRS 321
            S S SR R R   R  SRSRS SR   R+SR RS
Sbjct: 760 SSGSYSRSRSRSCSRSYSRSRSRSRSRSRSSRSRS 794


>gi|21361282 splicing factor, arginine/serine-rich 4 [Homo sapiens]
          Length = 494

 Score = 60.5 bits (145), Expect = 2e-09
 Identities = 50/175 (28%), Positives = 82/175 (46%), Gaps = 6/175 (3%)

Query: 154 KILMEVEKVRAKKKEAEEEYRNSMPASSFQQQKLRVCEVCSAYLGLHDNDRRLADHFGGK 213
           ++++E    R   ++ ++  R +   +     K R  E    ++   D  R L    G +
Sbjct: 105 RLIVENLSSRCSWQDLKDYMRQAGEVTYADAHKGRKNEGVIEFVSYSDMKRALEKLDGTE 164

Query: 214 LHLGFIQ-IREKLDQLRKTVAEKQEKRNQDRLRRREEREREERL--SRRSGSRTRDRRRS 270
           ++   I+ + +K    R+    +    ++ R R R  R+   R   S+ S S++R R RS
Sbjct: 165 VNGRKIRLVEDKPGSRRRRSYSRSRSHSRSRSRSRHSRKSRSRSGSSKSSHSKSRSRSRS 224

Query: 271 RSRDRRRRRSRSTSRERRKLSRSRSRDRHRRHRSRSRSHSRGHRRASRDRSAKYK 325
            SR R + RSRS SR R K  +SRS     + +SRSRSHS G  R+     A+ K
Sbjct: 225 GSRSRSKSRSRSQSRSRSKKEKSRSPS---KEKSRSRSHSAGKSRSKSKDQAEEK 276



 Score = 59.7 bits (143), Expect = 3e-09
 Identities = 35/97 (36%), Positives = 52/97 (53%), Gaps = 5/97 (5%)

Query: 227 QLRKTVAEKQEKRNQDRLRRREEREREERLSRRSGSRTRDRRRSRSRDRRRRRSRSTSRE 286
           Q R+   EK+   ++ R + +  R+   R   + GSR+R R RS+S+D+R+ R RS    
Sbjct: 305 QERRVEEEKRGSVSRGRSQEKSLRQSRSRSRSKGGSRSRSRSRSKSKDKRKGRKRS---- 360

Query: 287 RRKLSRSRSRDRHRRHRSRSRSHSRGHRRASRDRSAK 323
            R+ SRSRSR R +  RSR R   R  +  S  +  K
Sbjct: 361 -REESRSRSRSRSKSERSRKRGSKRDSKAGSSKKKKK 396



 Score = 58.2 bits (139), Expect = 1e-08
 Identities = 36/107 (33%), Positives = 55/107 (51%), Gaps = 2/107 (1%)

Query: 219 IQIREKLDQLRKTVAEKQEKRNQDRLRRREEREREERLSRRSGSRTRDR--RRSRSRDRR 276
           IQ  + + + +     + + +++ R R +E R  EE+    S  R++++  R+SRSR R 
Sbjct: 277 IQNNDNVGKPKSRSPSRHKSKSKSRSRSQERRVEEEKRGSVSRGRSQEKSLRQSRSRSRS 336

Query: 277 RRRSRSTSRERRKLSRSRSRDRHRRHRSRSRSHSRGHRRASRDRSAK 323
           +  SRS SR R K    R   +  R  SRSRS SR     SR R +K
Sbjct: 337 KGGSRSRSRSRSKSKDKRKGRKRSREESRSRSRSRSKSERSRKRGSK 383



 Score = 58.2 bits (139), Expect = 1e-08
 Identities = 38/97 (39%), Positives = 54/97 (55%), Gaps = 2/97 (2%)

Query: 230 KTVAEKQEKRNQDRLRRREERER-EERLSRRSGSRTRDRRRSRSRDRRRRRSRSTSRERR 288
           K+ +  QE+R ++  R    R R +E+  R+S SR+R +  SRSR R R +S+   R+ R
Sbjct: 299 KSRSRSQERRVEEEKRGSVSRGRSQEKSLRQSRSRSRSKGGSRSRSRSRSKSKD-KRKGR 357

Query: 289 KLSRSRSRDRHRRHRSRSRSHSRGHRRASRDRSAKYK 325
           K SR  SR R R      RS  RG +R S+  S+K K
Sbjct: 358 KRSREESRSRSRSRSKSERSRKRGSKRDSKAGSSKKK 394



 Score = 52.0 bits (123), Expect = 7e-07
 Identities = 61/254 (24%), Positives = 107/254 (42%), Gaps = 30/254 (11%)

Query: 100 RTELAKKRLAETQEEISAEVSAKAEKVHELN-EEIGKLLAKAEQLGAEGNVDESQKILME 158
           R+   K++     +E S   S  A K    + ++  + +   + +G   +   S+     
Sbjct: 239 RSRSKKEKSRSPSKEKSRSRSHSAGKSRSKSKDQAEEKIQNNDNVGKPKSRSPSRHKSKS 298

Query: 159 VEKVRAKKKEAEEEYRNSMPASSFQQQKLRVCEVCSAYLG---------LHDNDRRLADH 209
             + R++++  EEE R S+     Q++ LR     S   G             D+R    
Sbjct: 299 KSRSRSQERRVEEEKRGSVSRGRSQEKSLRQSRSRSRSKGGSRSRSRSRSKSKDKRKGRK 358

Query: 210 FGGKLHLGFIQIREKLDQLRKTVAEKQEKRNQDRLRRREEREREE-RLSRRSGSRTRDRR 268
              +      + R K ++ RK  +++  K    + +++E+ +R + R   RS S+ R+  
Sbjct: 359 RSREESRSRSRSRSKSERSRKRGSKRDSKAGSSKKKKKEDTDRSQSRSPSRSVSKEREHA 418

Query: 269 RSRSRDRR--------------RRRSRSTSRERRKL---SRSRSRDRHRRHRSRSRSHSR 311
           +S S  R               R RSRS S+ +  L   SRSRS+   +  RSRS+S SR
Sbjct: 419 KSESSQREGRGESENAGTNQETRSRSRSNSKSKPNLPSESRSRSKSASKT-RSRSKSRSR 477

Query: 312 GHRRA-SRDRSAKY 324
              R+ SR RS  +
Sbjct: 478 SASRSPSRSRSRSH 491



 Score = 48.5 bits (114), Expect = 8e-06
 Identities = 44/224 (19%), Positives = 91/224 (40%), Gaps = 19/224 (8%)

Query: 100 RTELAKKRLAETQEEISAEVSAKAEKVHELNEEIGKLLAKAEQLGAEGNVDESQKILMEV 159
           R+    +  ++++    +   +K EK    ++E  +  + +       + D++++ +   
Sbjct: 221 RSRSGSRSRSKSRSRSQSRSRSKKEKSRSPSKEKSRSRSHSAGKSRSKSKDQAEEKIQNN 280

Query: 160 EKVRAKKKEAEEEYRNSMPASSFQQQKLRVCEVCSAYLGLHDNDRRLADHFGGKLHLGFI 219
           + V   K  +   +++   + S  Q+                  RR+ +   G +  G  
Sbjct: 281 DNVGKPKSRSPSRHKSKSKSRSRSQE------------------RRVEEEKRGSVSRGRS 322

Query: 220 QIREKLDQLRKTVAEKQEKRNQDRLRRREEREREERLSRRSGSRTRDRRRSRSRDRRRRR 279
           Q  + L Q R     K   R++ R R + + +R+ R   R  SR+R R RS+S   R+R 
Sbjct: 323 Q-EKSLRQSRSRSRSKGGSRSRSRSRSKSKDKRKGRKRSREESRSRSRSRSKSERSRKRG 381

Query: 280 SRSTSRERRKLSRSRSRDRHRRHRSRSRSHSRGHRRASRDRSAK 323
           S+  S+      + +      + RS SRS S+    A  + S +
Sbjct: 382 SKRDSKAGSSKKKKKEDTDRSQSRSPSRSVSKEREHAKSESSQR 425



 Score = 35.0 bits (79), Expect = 0.091
 Identities = 32/116 (27%), Positives = 49/116 (42%), Gaps = 30/116 (25%)

Query: 229 RKTVAEKQEKRNQDRLRRREEREREERLSRRSGSRTR--------DRRRS---RSRDRRR 277
           R     +  ++++ R    +    + R   RSGSR+R         R RS   +SR   +
Sbjct: 193 RSRSRSRHSRKSRSRSGSSKSSHSKSRSRSRSGSRSRSKSRSRSQSRSRSKKEKSRSPSK 252

Query: 278 RRSRSTSRERRKLSRSRSRDRHR------------------RHRSRSRSHSRGHRR 315
            +SRS S    K SRS+S+D+                    RH+S+S+S SR   R
Sbjct: 253 EKSRSRSHSAGK-SRSKSKDQAEEKIQNNDNVGKPKSRSPSRHKSKSKSRSRSQER 307


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.318    0.130    0.358 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 10,707,575
Number of Sequences: 37866
Number of extensions: 472269
Number of successful extensions: 18838
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 492
Number of HSP's successfully gapped in prelim test: 572
Number of HSP's that attempted gapping in prelim test: 5211
Number of HSP's gapped (non-prelim): 5874
length of query: 325
length of database: 18,247,518
effective HSP length: 102
effective length of query: 223
effective length of database: 14,385,186
effective search space: 3207896478
effective search space used: 3207896478
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 62 (28.5 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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