Guide to the Human Genome
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Search of human proteins with 88943446

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|88943446 PREDICTED: similar to Kinase suppressor of Ras 1
[Homo sapiens]
         (76 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|88943446 PREDICTED: similar to Kinase suppressor of Ras 1 [Ho...   157   2e-39
gi|169217819 PREDICTED: similar to hCG1793095 [Homo sapiens]           73   4e-14
gi|167621456 kinase suppressor of ras 2 [Homo sapiens]                 40   3e-04
gi|194018478 TBC1 domain family, member 2B isoform a [Homo sapiens]    31   0.19 
gi|194018476 TBC1 domain family, member 2B isoform b [Homo sapiens]    31   0.19 
gi|46430491 scratch 2 protein [Homo sapiens]                           30   0.32 
gi|41281831 neuronal PAS domain protein 3 isoform 2 [Homo sapiens]     30   0.42 
gi|11545847 neuronal PAS domain protein 3 isoform 1 [Homo sapiens]     30   0.42 
gi|239743123 PREDICTED: hypothetical protein [Homo sapiens]            29   0.72 
gi|169171388 PREDICTED: hypothetical protein [Homo sapiens]            29   0.93 
gi|239749096 PREDICTED: hypothetical protein [Homo sapiens]            29   0.93 
gi|24497506 forkhead box A3 [Homo sapiens]                             28   1.2  
gi|170650694 centaurin, gamma 1 isoform PIKE-L [Homo sapiens]          28   2.1  
gi|116734702 homeobox D13 [Homo sapiens]                               28   2.1  
gi|52353288 olfactory receptor, family 8, subfamily D, member 4 ...    28   2.1  
gi|74027251 tripartite motif-containing 33 protein isoform beta ...    27   2.7  
gi|74027249 tripartite motif-containing 33 protein isoform alpha...    27   2.7  
gi|42558258 F-box protein 33 [Homo sapiens]                            27   2.7  
gi|21264565 AT rich interactive domain 1A isoform a [Homo sapiens]     27   2.7  
gi|21264575 AT rich interactive domain 1A isoform b [Homo sapiens]     27   2.7  
gi|29570782 additional sex combs like 1 [Homo sapiens]                 27   3.5  
gi|7705773 SH3-containing protein SH3GLB1 [Homo sapiens]               27   3.5  
gi|50897282 olfactory receptor, family 8, subfamily D, member 1 ...    27   3.5  
gi|153791670 keratin 76 [Homo sapiens]                                 27   4.6  
gi|24308237 phosphatidylinositol transfer protein, membrane-asso...    27   4.6  
gi|4507161 SRY-box 11 [Homo sapiens]                                   27   4.6  
gi|4758630 potassium voltage-gated channel KQT-like protein 3 [H...    27   4.6  
gi|33286428 solute carrier family 7 (cationic amino acid transpo...    27   4.6  
gi|40068464 AT rich interactive domain 1B (SWI1-like) isoform 2 ...    27   4.6  
gi|40068466 AT rich interactive domain 1B (SWI1-like) isoform 1 ...    27   4.6  

>gi|88943446 PREDICTED: similar to Kinase suppressor of Ras 1
          [Homo sapiens]
          Length = 76

 Score =  157 bits (396), Expect = 2e-39
 Identities = 76/76 (100%), Positives = 76/76 (100%)

Query: 1  MGEKKEGGGGGDAAATEGGTGAAASRALQQCGQLQKLIVIFIGSLCGLCTKCAVSNDLTQ 60
          MGEKKEGGGGGDAAATEGGTGAAASRALQQCGQLQKLIVIFIGSLCGLCTKCAVSNDLTQ
Sbjct: 1  MGEKKEGGGGGDAAATEGGTGAAASRALQQCGQLQKLIVIFIGSLCGLCTKCAVSNDLTQ 60

Query: 61 QEIQTLEILFNIPHHG 76
          QEIQTLEILFNIPHHG
Sbjct: 61 QEIQTLEILFNIPHHG 76


>gi|169217819 PREDICTED: similar to hCG1793095 [Homo sapiens]
          Length = 167

 Score = 73.2 bits (178), Expect = 4e-14
 Identities = 41/58 (70%), Positives = 44/58 (75%), Gaps = 4/58 (6%)

Query: 11  GDAAATEGGTGAAASRALQQCGQLQKLIVIFIGSLCGLCTKCAVSNDLTQQEIQTLEI 68
           G+     G  GAAASRALQQCGQLQ LI    GSL GL TKCAVSNDLTQQEI+TLE+
Sbjct: 85  GEYCPRMGPGGAAASRALQQCGQLQNLI----GSLRGLRTKCAVSNDLTQQEIRTLEV 138


>gi|167621456 kinase suppressor of ras 2 [Homo sapiens]
          Length = 921

 Score = 40.4 bits (93), Expect = 3e-04
 Identities = 20/31 (64%), Positives = 25/31 (80%)

Query: 37 LIVIFIGSLCGLCTKCAVSNDLTQQEIQTLE 67
          +I + I +L GL TKCA SNDLTQ+EI+TLE
Sbjct: 1  MIDLSISNLEGLRTKCATSNDLTQKEIRTLE 31


>gi|194018478 TBC1 domain family, member 2B isoform a [Homo
          sapiens]
          Length = 963

 Score = 31.2 bits (69), Expect = 0.19
 Identities = 19/37 (51%), Positives = 22/37 (59%), Gaps = 5/37 (13%)

Query: 5  KEGGGGGD----AAATEGGTGAAASRALQQCGQLQKL 37
          +EGGGGG+     AA E G G A   A + CG LQKL
Sbjct: 9  EEGGGGGEGAAQGAAAEPGAGPAREPA-RLCGYLQKL 44


>gi|194018476 TBC1 domain family, member 2B isoform b [Homo
          sapiens]
          Length = 914

 Score = 31.2 bits (69), Expect = 0.19
 Identities = 19/37 (51%), Positives = 22/37 (59%), Gaps = 5/37 (13%)

Query: 5  KEGGGGGD----AAATEGGTGAAASRALQQCGQLQKL 37
          +EGGGGG+     AA E G G A   A + CG LQKL
Sbjct: 9  EEGGGGGEGAAQGAAAEPGAGPAREPA-RLCGYLQKL 44


>gi|46430491 scratch 2 protein [Homo sapiens]
          Length = 307

 Score = 30.4 bits (67), Expect = 0.32
 Identities = 15/31 (48%), Positives = 18/31 (58%), Gaps = 2/31 (6%)

Query: 4   KKEGGGGGDAAAT--EGGTGAAASRALQQCG 32
           ++ GGGGGDA  +   GG G  A RA  Q G
Sbjct: 120 RRRGGGGGDAGGSGDAGGAGGRAGRAGAQAG 150


>gi|41281831 neuronal PAS domain protein 3 isoform 2 [Homo sapiens]
          Length = 920

 Score = 30.0 bits (66), Expect = 0.42
 Identities = 14/31 (45%), Positives = 17/31 (54%)

Query: 7   GGGGGDAAATEGGTGAAASRALQQCGQLQKL 37
           GGGGG      GG G +AS +L   G L+ L
Sbjct: 750 GGGGGGGGGGAGGGGPSASNSLLYTGDLEAL 780


>gi|11545847 neuronal PAS domain protein 3 isoform 1 [Homo sapiens]
          Length = 901

 Score = 30.0 bits (66), Expect = 0.42
 Identities = 14/31 (45%), Positives = 17/31 (54%)

Query: 7   GGGGGDAAATEGGTGAAASRALQQCGQLQKL 37
           GGGGG      GG G +AS +L   G L+ L
Sbjct: 731 GGGGGGGGGGAGGGGPSASNSLLYTGDLEAL 761


>gi|239743123 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 123

 Score = 29.3 bits (64), Expect = 0.72
 Identities = 12/23 (52%), Positives = 13/23 (56%)

Query: 1  MGEKKEGGGGGDAAATEGGTGAA 23
          +   K GGGGG A   EGG G A
Sbjct: 15 LNNHKGGGGGGGAGGAEGGAGGA 37


>gi|169171388 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 154

 Score = 28.9 bits (63), Expect = 0.93
 Identities = 12/19 (63%), Positives = 12/19 (63%)

Query: 5  KEGGGGGDAAATEGGTGAA 23
          K GGGGG A   EGG G A
Sbjct: 50 KGGGGGGGAGGAEGGAGGA 68


>gi|239749096 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 154

 Score = 28.9 bits (63), Expect = 0.93
 Identities = 12/19 (63%), Positives = 12/19 (63%)

Query: 5  KEGGGGGDAAATEGGTGAA 23
          K GGGGG A   EGG G A
Sbjct: 50 KGGGGGGGAGGAEGGAGGA 68


>gi|24497506 forkhead box A3 [Homo sapiens]
          Length = 350

 Score = 28.5 bits (62), Expect = 1.2
 Identities = 13/23 (56%), Positives = 15/23 (65%)

Query: 3   EKKEGGGGGDAAATEGGTGAAAS 25
           EK + GG G A  T  GTG+AAS
Sbjct: 217 EKVKKGGSGAATTTRNGTGSAAS 239


>gi|170650694 centaurin, gamma 1 isoform PIKE-L [Homo sapiens]
          Length = 1192

 Score = 27.7 bits (60), Expect = 2.1
 Identities = 11/17 (64%), Positives = 12/17 (70%)

Query: 8   GGGGDAAATEGGTGAAA 24
           GGGG  A+T GG GA A
Sbjct: 244 GGGGSTASTSGGVGAGA 260


>gi|116734702 homeobox D13 [Homo sapiens]
          Length = 343

 Score = 27.7 bits (60), Expect = 2.1
 Identities = 12/30 (40%), Positives = 17/30 (56%)

Query: 2  GEKKEGGGGGDAAATEGGTGAAASRALQQC 31
          G + +GGG G A A+   +  AA+ A  QC
Sbjct: 11 GLRADGGGAGGAPASSSSSSVAAAAASGQC 40


>gi|52353288 olfactory receptor, family 8, subfamily D, member 4
           [Homo sapiens]
          Length = 314

 Score = 27.7 bits (60), Expect = 2.1
 Identities = 12/41 (29%), Positives = 23/41 (56%)

Query: 26  RALQQCGQLQKLIVIFIGSLCGLCTKCAVSNDLTQQEIQTL 66
           +A   C      +++F GSL  +  K A S+ LTQ+++ ++
Sbjct: 236 KAFSTCSSHLTAVLMFYGSLMSMYLKPASSSSLTQEKVSSV 276


>gi|74027251 tripartite motif-containing 33 protein isoform beta
          [Homo sapiens]
          Length = 1110

 Score = 27.3 bits (59), Expect = 2.7
 Identities = 14/27 (51%), Positives = 15/27 (55%), Gaps = 1/27 (3%)

Query: 2  GEKKEGGGG-GDAAATEGGTGAAASRA 27
          GE + GGGG G A  T G  G AA  A
Sbjct: 8  GEAESGGGGSGSAPVTAGAAGPAAQEA 34


>gi|74027249 tripartite motif-containing 33 protein isoform alpha
          [Homo sapiens]
          Length = 1127

 Score = 27.3 bits (59), Expect = 2.7
 Identities = 14/27 (51%), Positives = 15/27 (55%), Gaps = 1/27 (3%)

Query: 2  GEKKEGGGG-GDAAATEGGTGAAASRA 27
          GE + GGGG G A  T G  G AA  A
Sbjct: 8  GEAESGGGGSGSAPVTAGAAGPAAQEA 34


>gi|42558258 F-box protein 33 [Homo sapiens]
          Length = 555

 Score = 27.3 bits (59), Expect = 2.7
 Identities = 15/56 (26%), Positives = 27/56 (48%), Gaps = 2/56 (3%)

Query: 7   GGGGGDAAATEGGTGAAASRALQQCGQLQKLIVIFIGSLCGLCTKCAVSNDLTQQE 62
           GGG GD    + GTG     ALQ   +  +++  ++  +  LC   ++ N+   Q+
Sbjct: 151 GGGPGDGGGADTGTGGEEVEALQLSARWLEVLRTYLELV--LCVLVSIRNNRNLQK 204


>gi|21264565 AT rich interactive domain 1A isoform a [Homo
          sapiens]
          Length = 2285

 Score = 27.3 bits (59), Expect = 2.7
 Identities = 11/21 (52%), Positives = 13/21 (61%)

Query: 2  GEKKEGGGGGDAAATEGGTGA 22
          G +  GGGGG  A + GG GA
Sbjct: 76 GAESNGGGGGGGAGSGGGPGA 96


>gi|21264575 AT rich interactive domain 1A isoform b [Homo
          sapiens]
          Length = 2068

 Score = 27.3 bits (59), Expect = 2.7
 Identities = 11/21 (52%), Positives = 13/21 (61%)

Query: 2  GEKKEGGGGGDAAATEGGTGA 22
          G +  GGGGG  A + GG GA
Sbjct: 76 GAESNGGGGGGGAGSGGGPGA 96


>gi|29570782 additional sex combs like 1 [Homo sapiens]
          Length = 1541

 Score = 26.9 bits (58), Expect = 3.5
 Identities = 11/26 (42%), Positives = 15/26 (57%)

Query: 7   GGGGGDAAATEGGTGAAASRALQQCG 32
           GGGGG A    GG G+++    + CG
Sbjct: 648 GGGGGGATDEGGGRGSSSGDGGEACG 673


>gi|7705773 SH3-containing protein SH3GLB1 [Homo sapiens]
          Length = 365

 Score = 26.9 bits (58), Expect = 3.5
 Identities = 13/25 (52%), Positives = 15/25 (60%)

Query: 14  AATEGGTGAAASRALQQCGQLQKLI 38
           A TE G G A   AL +CG+ QK I
Sbjct: 104 AGTEFGPGTAYGNALIKCGETQKRI 128


>gi|50897282 olfactory receptor, family 8, subfamily D, member 1
           [Homo sapiens]
          Length = 308

 Score = 26.9 bits (58), Expect = 3.5
 Identities = 15/49 (30%), Positives = 24/49 (48%)

Query: 25  SRALQQCGQLQKLIVIFIGSLCGLCTKCAVSNDLTQQEIQTLEILFNIP 73
           S+A   C      +VIF GS+  +  K   SN L Q+++ ++     IP
Sbjct: 235 SKAFGTCSSHLMAVVIFFGSITFMYFKPPSSNSLDQEKVSSVFYTTVIP 283


>gi|153791670 keratin 76 [Homo sapiens]
          Length = 638

 Score = 26.6 bits (57), Expect = 4.6
 Identities = 11/35 (31%), Positives = 17/35 (48%)

Query: 5  KEGGGGGDAAATEGGTGAAASRALQQCGQLQKLIV 39
          + GG GG A     G G+  SR+L   G  + + +
Sbjct: 35 RSGGAGGGACGFRSGAGSFGSRSLYNLGSNKSISI 69


>gi|24308237 phosphatidylinositol transfer protein,
           membrane-associated 2 [Homo sapiens]
          Length = 1349

 Score = 26.6 bits (57), Expect = 4.6
 Identities = 10/30 (33%), Positives = 16/30 (53%)

Query: 7   GGGGGDAAATEGGTGAAASRALQQCGQLQK 36
           GGGGG    + GG G++   +L+    L +
Sbjct: 614 GGGGGGGGGSSGGGGSSGGSSLESSRHLSR 643


>gi|4507161 SRY-box 11 [Homo sapiens]
          Length = 441

 Score = 26.6 bits (57), Expect = 4.6
 Identities = 11/33 (33%), Positives = 18/33 (54%)

Query: 3   EKKEGGGGGDAAATEGGTGAAASRALQQCGQLQ 35
           EK   GGGG +A    G    +  + ++CG+L+
Sbjct: 139 EKSAAGGGGGSAGGGAGGAKTSKGSSKKCGKLK 171


>gi|4758630 potassium voltage-gated channel KQT-like protein 3
          [Homo sapiens]
          Length = 872

 Score = 26.6 bits (57), Expect = 4.6
 Identities = 13/26 (50%), Positives = 15/26 (57%)

Query: 7  GGGGGDAAATEGGTGAAASRALQQCG 32
          GGGGG AA   GG  AAA    ++ G
Sbjct: 19 GGGGGGAANPAGGDAAAAGDEERKVG 44


>gi|33286428 solute carrier family 7 (cationic amino acid
          transporter, y+ system), member 8 isoform a [Homo
          sapiens]
          Length = 535

 Score = 26.6 bits (57), Expect = 4.6
 Identities = 15/45 (33%), Positives = 22/45 (48%), Gaps = 1/45 (2%)

Query: 3  EKKEGGGGGDAAATEGGTGAAASRALQQCGQLQKLIVIFIGSLCG 47
          EKK  GGG   A+ E G+G       ++ G L     I +G++ G
Sbjct: 12 EKKHPGGGESDASPEAGSGGGGVALKKEIG-LVSACGIIVGNIIG 55


>gi|40068464 AT rich interactive domain 1B (SWI1-like) isoform 2
           [Homo sapiens]
          Length = 2191

 Score = 26.6 bits (57), Expect = 4.6
 Identities = 12/21 (57%), Positives = 12/21 (57%)

Query: 7   GGGGGDAAATEGGTGAAASRA 27
           GGGGG   A  GG GA A  A
Sbjct: 263 GGGGGGGGAGAGGAGAGAVAA 283



 Score = 26.6 bits (57), Expect = 4.6
 Identities = 12/21 (57%), Positives = 13/21 (61%)

Query: 7   GGGGGDAAATEGGTGAAASRA 27
           GGGGG A A   G GA A+ A
Sbjct: 265 GGGGGGAGAGGAGAGAVAAAA 285


>gi|40068466 AT rich interactive domain 1B (SWI1-like) isoform 1
           [Homo sapiens]
          Length = 2231

 Score = 26.6 bits (57), Expect = 4.6
 Identities = 12/21 (57%), Positives = 12/21 (57%)

Query: 7   GGGGGDAAATEGGTGAAASRA 27
           GGGGG   A  GG GA A  A
Sbjct: 263 GGGGGGGGAGAGGAGAGAVAA 283



 Score = 26.6 bits (57), Expect = 4.6
 Identities = 12/21 (57%), Positives = 13/21 (61%)

Query: 7   GGGGGDAAATEGGTGAAASRA 27
           GGGGG A A   G GA A+ A
Sbjct: 265 GGGGGGAGAGGAGAGAVAAAA 285


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.317    0.136    0.404 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 3,061,052
Number of Sequences: 37866
Number of extensions: 110536
Number of successful extensions: 1434
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 37
Number of HSP's successfully gapped in prelim test: 12
Number of HSP's that attempted gapping in prelim test: 1293
Number of HSP's gapped (non-prelim): 133
length of query: 76
length of database: 18,247,518
effective HSP length: 48
effective length of query: 28
effective length of database: 16,429,950
effective search space: 460038600
effective search space used: 460038600
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 55 (25.8 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
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