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Search of human proteins with 88759339
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|88759339 aster-associated protein [Homo sapiens]
(647 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|88759339 aster-associated protein [Homo sapiens] 1265 0.0
gi|63054848 coiled-coil domain containing 34 isoform 1 [Homo sap... 88 2e-17
gi|239754909 PREDICTED: hypothetical protein [Homo sapiens] 84 3e-16
gi|102467242 inner centromere protein antigens 135/155kDa isofor... 83 7e-16
gi|102467235 inner centromere protein antigens 135/155kDa isofor... 82 2e-15
gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-li... 79 1e-14
gi|44680105 caldesmon 1 isoform 1 [Homo sapiens] 79 2e-14
gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-li... 77 5e-14
gi|55741709 RNA binding motif protein 25 [Homo sapiens] 76 1e-13
gi|239749449 PREDICTED: hypothetical protein [Homo sapiens] 75 2e-13
gi|148746195 trichohyalin [Homo sapiens] 75 2e-13
gi|134948605 ankyrin repeat domain 12 isoform 2 [Homo sapiens] 75 2e-13
gi|134948558 ankyrin repeat domain 12 isoform 1 [Homo sapiens] 75 2e-13
gi|56676397 ankyrin repeat domain 11 [Homo sapiens] 74 3e-13
gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo sa... 73 9e-13
gi|239745079 PREDICTED: Putative golgin subfamily A member 6-lik... 73 9e-13
gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens] 71 3e-12
gi|84043963 eukaryotic translation initiation factor 5B [Homo sa... 71 3e-12
gi|109134347 NY-REN-58 antigen [Homo sapiens] 71 3e-12
gi|109134355 NY-REN-58 antigen [Homo sapiens] 71 3e-12
gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo sa... 70 5e-12
gi|42560244 peptidylprolyl isomerase G [Homo sapiens] 70 5e-12
gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo sap... 69 1e-11
gi|115298682 HBxAg transactivated protein 2 [Homo sapiens] 69 1e-11
gi|239745127 PREDICTED: similar to Putative golgin subfamily A m... 69 1e-11
gi|87299628 biorientation of chromosomes in cell division 1-like... 69 2e-11
gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens] 68 3e-11
gi|95147555 microtubule-associated protein 1A [Homo sapiens] 67 4e-11
gi|239745153 PREDICTED: similar to Putative golgin subfamily A m... 67 5e-11
gi|221219020 NYD-SP11 protein [Homo sapiens] 67 7e-11
>gi|88759339 aster-associated protein [Homo sapiens]
Length = 647
Score = 1265 bits (3274), Expect = 0.0
Identities = 647/647 (100%), Positives = 647/647 (100%)
Query: 1 MSDEVFSTTLAYTKSPKVTKRTTFQDELIRAITARSARQRSSEYSDDFDSDEIVSLGDFS 60
MSDEVFSTTLAYTKSPKVTKRTTFQDELIRAITARSARQRSSEYSDDFDSDEIVSLGDFS
Sbjct: 1 MSDEVFSTTLAYTKSPKVTKRTTFQDELIRAITARSARQRSSEYSDDFDSDEIVSLGDFS 60
Query: 61 DTSADENSVNKKMNDFHISDDEEKNPSKLLFLKTNKSNGNITKDEPVCAIKNEEEMAPDG 120
DTSADENSVNKKMNDFHISDDEEKNPSKLLFLKTNKSNGNITKDEPVCAIKNEEEMAPDG
Sbjct: 61 DTSADENSVNKKMNDFHISDDEEKNPSKLLFLKTNKSNGNITKDEPVCAIKNEEEMAPDG 120
Query: 121 CEDIVVKSFSESQNKDEEFEKDKIKMKPKPRILSIKSTSSAENNSLDTDDHFKPSPRPRS 180
CEDIVVKSFSESQNKDEEFEKDKIKMKPKPRILSIKSTSSAENNSLDTDDHFKPSPRPRS
Sbjct: 121 CEDIVVKSFSESQNKDEEFEKDKIKMKPKPRILSIKSTSSAENNSLDTDDHFKPSPRPRS 180
Query: 181 MLKKKSHMEEKDGLEDKETALSEELELHSAPSSLPTPNGIQLEAEKKAFSENLDPEDSCL 240
MLKKKSHMEEKDGLEDKETALSEELELHSAPSSLPTPNGIQLEAEKKAFSENLDPEDSCL
Sbjct: 181 MLKKKSHMEEKDGLEDKETALSEELELHSAPSSLPTPNGIQLEAEKKAFSENLDPEDSCL 240
Query: 241 TSLASSSLKQILGDSFSPGSEGNASGKDPNEEITENHNSLKSDENKENSFSADHVTTAVE 300
TSLASSSLKQILGDSFSPGSEGNASGKDPNEEITENHNSLKSDENKENSFSADHVTTAVE
Sbjct: 241 TSLASSSLKQILGDSFSPGSEGNASGKDPNEEITENHNSLKSDENKENSFSADHVTTAVE 300
Query: 301 KSKESQVTADDLEEEKAKAELIMDDDRTVDPLLSKSQSILISTSATASSKKTIEDRNIKN 360
KSKESQVTADDLEEEKAKAELIMDDDRTVDPLLSKSQSILISTSATASSKKTIEDRNIKN
Sbjct: 301 KSKESQVTADDLEEEKAKAELIMDDDRTVDPLLSKSQSILISTSATASSKKTIEDRNIKN 360
Query: 361 KKSTNNRASSASARLMTSEFLKKSSSKRRTPSTTTSSHYLGTLKVLDQKPSQKQSIEPDR 420
KKSTNNRASSASARLMTSEFLKKSSSKRRTPSTTTSSHYLGTLKVLDQKPSQKQSIEPDR
Sbjct: 361 KKSTNNRASSASARLMTSEFLKKSSSKRRTPSTTTSSHYLGTLKVLDQKPSQKQSIEPDR 420
Query: 421 ADNIRAAVYQEWLEKKNVYLHEMHRIKRIESENLRIQNEQKKAAKREEALASFEAWKAMK 480
ADNIRAAVYQEWLEKKNVYLHEMHRIKRIESENLRIQNEQKKAAKREEALASFEAWKAMK
Sbjct: 421 ADNIRAAVYQEWLEKKNVYLHEMHRIKRIESENLRIQNEQKKAAKREEALASFEAWKAMK 480
Query: 481 EKEAKKIAAKKRLEEKNKKKTEEENAARKGEALQAFEKWKEKKMEYLKEKNRKEREYERA 540
EKEAKKIAAKKRLEEKNKKKTEEENAARKGEALQAFEKWKEKKMEYLKEKNRKEREYERA
Sbjct: 481 EKEAKKIAAKKRLEEKNKKKTEEENAARKGEALQAFEKWKEKKMEYLKEKNRKEREYERA 540
Query: 541 KKQKEEETVAEKKKDNLTAVEKWNEKKEAFFKQKEKEKINEKRKEELKRAEKKDKDKQAI 600
KKQKEEETVAEKKKDNLTAVEKWNEKKEAFFKQKEKEKINEKRKEELKRAEKKDKDKQAI
Sbjct: 541 KKQKEEETVAEKKKDNLTAVEKWNEKKEAFFKQKEKEKINEKRKEELKRAEKKDKDKQAI 600
Query: 601 NEYEKWLENKEKQERIERKQKKRHSFLESEALPPWSPPSRTVFAKVF 647
NEYEKWLENKEKQERIERKQKKRHSFLESEALPPWSPPSRTVFAKVF
Sbjct: 601 NEYEKWLENKEKQERIERKQKKRHSFLESEALPPWSPPSRTVFAKVF 647
>gi|63054848 coiled-coil domain containing 34 isoform 1 [Homo
sapiens]
Length = 373
Score = 88.2 bits (217), Expect = 2e-17
Identities = 71/211 (33%), Positives = 104/211 (49%), Gaps = 30/211 (14%)
Query: 448 RIESENLRIQNEQKKAAKREEALASFEAWKAMKEKEAKKIAAKKRLEEKN----KKKTEE 503
++ESEN Q EQK+ E L +E W KEKE + K LEE N K+K E
Sbjct: 122 QVESENN--QEEQKQVRLPESRLTPWEVWFIGKEKEERDRLQLKALEELNQQLEKRKEME 179
Query: 504 ENAARKGEALQAFEKWKEKKMEYLKEKNRKEREYERAKKQKEEETVAEKKKDNLTAVEKW 563
E RK A + ++W +KK E+ RKERE ++ K+ EE+ E +K+ L EK
Sbjct: 180 EREKRKIIAEEKHKEWVQKK----NEQKRKERE-QKINKEMEEKAAKELEKEYLQ--EKA 232
Query: 564 NEKKEAFFKQKEKE----KINEKRKEELKRAEKKDKDKQAINEYEKWLENKEKQERIERK 619
EK + + K+K E K EK KE+ ++AE ++K + A ++++WLEN + + R K
Sbjct: 233 KEKYQEWLKKKNAEECERKKKEKEKEKQQQAEIQEKKEIAEKKFQEWLENAKHKPRPAAK 292
Query: 620 -----QKKRHSFLESEALP--------PWSP 637
K F + P PW P
Sbjct: 293 SYGYANGKLTGFYSGNSYPEPAFYNPIPWKP 323
Score = 51.2 bits (121), Expect = 3e-06
Identities = 38/152 (25%), Positives = 73/152 (48%), Gaps = 15/152 (9%)
Query: 420 RADNIRAAVYQEWLEKKNVYLHEMHRIKRIESENLRIQNEQKKAAKREEALASFEA---W 476
R R ++ W K + ++K +E N +++ ++ + + + + E W
Sbjct: 136 RLPESRLTPWEVWFIGKEKEERDRLQLKALEELNQQLEKRKEMEEREKRKIIAEEKHKEW 195
Query: 477 KAMKEKEAKKIAAKK---RLEEKNKKKTEEENAARKGEALQAFEKWKEKKMEYLKEKNRK 533
K ++ +K +K +EEK K+ E+E EK KEK E+LK+KN +
Sbjct: 196 VQKKNEQKRKEREQKINKEMEEKAAKELEKEYLQ---------EKAKEKYQEWLKKKNAE 246
Query: 534 EREYERAKKQKEEETVAEKKKDNLTAVEKWNE 565
E E ++ +K+KE++ AE ++ A +K+ E
Sbjct: 247 ECERKKKEKEKEKQQQAEIQEKKEIAEKKFQE 278
Score = 45.4 bits (106), Expect = 2e-04
Identities = 46/214 (21%), Positives = 94/214 (43%), Gaps = 13/214 (6%)
Query: 311 DLEEEKAKAELIMDDDRTVDPLLSKSQSILISTSATASSKKTIEDRNIKNKKSTNNRASS 370
D ++ + E +DD+ VD S++ + S +N + +
Sbjct: 78 DEDDGDGEDEEDVDDEEDVDEDAHDSEAKVASLRGMELQGCASTQVESENNQEEQKQVRL 137
Query: 371 ASARLMTSE--FLKKSSSKRRTPSTTTSSHYLGTLKVLDQKPSQKQSIEP-DRADNIRAA 427
+RL E F+ K +R L L+ L+Q+ +++ +E ++ I
Sbjct: 138 PESRLTPWEVWFIGKEKEER-------DRLQLKALEELNQQLEKRKEMEEREKRKIIAEE 190
Query: 428 VYQEWLEKKNVYLHEMHRIKRIESENLRIQNEQKKAAKREEALASFEAWKAMKEKEAKKI 487
++EW++KKN + K + + E +K +E+A ++ W +K+K A++
Sbjct: 191 KHKEWVQKKNEQKRKEREQKINKEMEEKAAKELEKEYLQEKAKEKYQEW--LKKKNAEEC 248
Query: 488 AAKKRLEEKNKKKTEEENAARKGEALQAFEKWKE 521
KK+ +EK K++ + E +K A + F++W E
Sbjct: 249 ERKKKEKEKEKQQ-QAEIQEKKEIAEKKFQEWLE 281
>gi|239754909 PREDICTED: hypothetical protein [Homo sapiens]
Length = 245
Score = 84.3 bits (207), Expect = 3e-16
Identities = 57/181 (31%), Positives = 96/181 (53%), Gaps = 7/181 (3%)
Query: 447 KRIESENLRIQNEQKKAAKREEALASFEAWKAMKEKEAKKIAA--KKRLEEKNKKKTEEE 504
K ESE + + E++K + E E K K+ E KK KKR EK K+ EE+
Sbjct: 53 KERESERKKERREREKRKREREKERKRERGKKEKKGERKKEERERKKRRREKENKEGEEK 112
Query: 505 NAARKGEALQAFEKWKEKKMEYLKEKNRKEREYERAKKQKEEETVAEKKKDNLTAVEKWN 564
+K E + KE K KE+ ++E ER +K++E E E+K+ ++
Sbjct: 113 EKRKKKEKKERGRTSKEGKERERKEERKREERKERERKKEEREKERERKERKKRERKQVG 172
Query: 565 EKKEAFFKQKEKEKINEKRKEELKRAEKKDKDKQAINEYEKWLENKEKQERIERKQKKRH 624
EK+E ++KEKE+ K++E ++ KK+++++ E +K E K+K+ER + +QK R
Sbjct: 173 EKEE---ERKEKERKERKKRERNRKERKKERERKERRERKK--ERKKKEERKKERQKDRQ 227
Query: 625 S 625
+
Sbjct: 228 T 228
Score = 78.2 bits (191), Expect = 2e-14
Identities = 48/173 (27%), Positives = 97/173 (56%), Gaps = 8/173 (4%)
Query: 460 QKKAAKREEALASFEAWKAMKEKEAKKIAAKKRLEEKNKKKTEEENAARKGEALQAFEKW 519
Q + +RE + + + K +E E KK ++R EK K++ E+E +G+ + E+
Sbjct: 35 QSEIREREREIETRKEGKKERESERKK---ERREREKRKREREKERKRERGKKEKKGERK 91
Query: 520 KEKK--MEYLKEKNRKEREYERAKKQKEEETVAEKKKDNLTAVEKWNEKKEAFFKQKEKE 577
KE++ + +EK KE E + +K+KE++ K+ K K+E ++KE+E
Sbjct: 92 KEERERKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKRE---ERKERE 148
Query: 578 KINEKRKEELKRAEKKDKDKQAINEYEKWLENKEKQERIERKQKKRHSFLESE 630
+ E+R++E +R E+K ++++ + E E+ + KE++ER +R++ ++ E E
Sbjct: 149 RKKEEREKERERKERKKRERKQVGEKEEERKEKERKERKKRERNRKERKKERE 201
Score = 74.7 bits (182), Expect = 2e-13
Identities = 62/215 (28%), Positives = 110/215 (51%), Gaps = 10/215 (4%)
Query: 412 QKQSIEPDRADNIRAAVYQEWLEKKNVYLHEMHRIKRIESENLRIQNEQKKAAKREEALA 471
Q + E +R R +E ++ E + KR E E R + KK K E
Sbjct: 35 QSEIREREREIETRKEGKKERESERKKERREREKRKR-EREKERKRERGKKEKKGERKKE 93
Query: 472 SFEAWKAMKEKEAKKIAAKKRLEEKNKK---KTEEENAARKGEALQAFEKWKEKKMEYLK 528
E K +EKE K+ K++ ++K KK +T +E R+ + + E+ KE++ + K
Sbjct: 94 ERERKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKERERK--K 151
Query: 529 EKNRKEREYERAKKQKEEETVAEKKKDNLTAVEKWNEKKEAFFKQKEKEKINEKRKEELK 588
E+ KERE + +K++E + V EK+++ K +K+E K+++KE+ ++R+E K
Sbjct: 152 EEREKERE-RKERKKRERKQVGEKEEERKEKERKERKKRERNRKERKKERERKERRERKK 210
Query: 589 RAEKKD--KDKQAINEYEKWLENKE-KQERIERKQ 620
+KK+ K ++ + W E + K+ER ERK+
Sbjct: 211 ERKKKEERKKERQKDRQTNWREKERGKRERKERKK 245
Score = 74.7 bits (182), Expect = 2e-13
Identities = 56/177 (31%), Positives = 100/177 (56%), Gaps = 18/177 (10%)
Query: 455 RIQNEQKKAAKREEALASFEAWKAMKEKEAKKIAAKKRLEEKNKKKTEE---ENAARKGE 511
R + ++++ ++R++ E K +EKE K+ KK E+K ++K EE + R+ E
Sbjct: 48 RKEGKKERESERKKERREREKRKREREKERKRERGKK--EKKGERKKEERERKKRRREKE 105
Query: 512 ALQAFEKWKEKKMEYLKEKNR-----KEREYERAKKQKEEETVAEKKKDNLTAVEKWNEK 566
+ EK K KK E KE+ R KERE + +K++E + KK++ EK E+
Sbjct: 106 NKEGEEKEKRKKKE-KKERGRTSKEGKERERKEERKREERKERERKKEER----EKERER 160
Query: 567 KEAFFKQKEKEKINEKRKEELKRAEKKDKDKQAINEYEKWLENKEKQERIERKQKKR 623
KE K++E++++ EK +EE K E+K++ K+ N E+ E + K+ R +K++K+
Sbjct: 161 KER--KKRERKQVGEK-EEERKEKERKERKKRERNRKERKKERERKERRERKKERKK 214
Score = 53.9 bits (128), Expect = 4e-07
Identities = 43/172 (25%), Positives = 85/172 (49%), Gaps = 12/172 (6%)
Query: 408 QKPSQKQSIEPDRADNIRAAVYQEWLEKKNVYLHEMHRIKRIESENL-RIQNEQKKAAKR 466
+K +++ E +R R +E EK+ E R E R + E++K +R
Sbjct: 85 EKKGERKKEERERKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREER 144
Query: 467 EEALASFEAWKAMKEKEAKKIAAKKRLEEKNKKKTEEENAARKGEALQAFEKWKEKKMEY 526
+E E + +E++ +K +K++ EK +++ E+E RK E+ KE++ +
Sbjct: 145 KERERKKEEREKERERKERKKRERKQVGEKEEERKEKERKERKKRERNRKERKKERERKE 204
Query: 527 LKEKNRKEREYERAKKQKEEETVAEKKKDNLTAVEKWNEKKEAFFKQKEKEK 578
+E+ +KER+ + +K+ E++KD T W EK+ ++KE++K
Sbjct: 205 RRER-KKERKKKEERKK-------ERQKDRQT---NWREKERGKRERKERKK 245
Score = 45.8 bits (107), Expect = 1e-04
Identities = 36/140 (25%), Positives = 68/140 (48%), Gaps = 7/140 (5%)
Query: 407 DQKPSQKQSIEPDRADNIRAAVYQEWLEKKNVYLHEMHRIKRIESENLRIQNEQKKAAKR 466
++K +K+ + +R + +E E++ + K+ E E R + E+KK ++
Sbjct: 110 EEKEKRKKKEKKERGRTSKEGKERERKEERKREERKERERKKEEREKERERKERKKRERK 169
Query: 467 EEALASFEAWKAMKEKEAKKIAAKKRLEEKNKKKTEEENAARKGEALQAFEKWKEKKMEY 526
+ E + KEKE K+ ++R K +KK E R E + +K +E+K E
Sbjct: 170 QVG----EKEEERKEKERKERKKRER-NRKERKKERERKERR--ERKKERKKKEERKKER 222
Query: 527 LKEKNRKEREYERAKKQKEE 546
K++ RE ER K++++E
Sbjct: 223 QKDRQTNWREKERGKRERKE 242
>gi|102467242 inner centromere protein antigens 135/155kDa isoform 2
[Homo sapiens]
Length = 914
Score = 83.2 bits (204), Expect = 7e-16
Identities = 101/490 (20%), Positives = 220/490 (44%), Gaps = 43/490 (8%)
Query: 150 PRILSIKSTSSAENNSLDTDDHFKPSPRPRSMLKKKSHMEEKDGLEDK-----------E 198
P S + S ++ S+ SP P+ + +K S + +++ + + E
Sbjct: 287 PDNFSTPTGSRTDSQSVRHSPIAPSSPSPQVLAQKYSLVAKQESVVRRASRRLAKKTAEE 346
Query: 199 TALSEELELHSAPSSLPTPNGIQLEAEKKAFSENLDP-EDSCLTSLASSSLKQILGDSFS 257
A S + HS L + +E +K SE +P E++ + A + + G++
Sbjct: 347 PAASGRIICHSYLERL-----LNVEVPQKVGSEQKEPPEEAEPVAAAEPEVPENNGNNSW 401
Query: 258 PGSEGNASGKDPNEEIT----ENHNSLKSDENKENSFSADHVTTAVEKSKESQVTADDLE 313
P ++ + PN + E ++ + + + + + + + + +L+
Sbjct: 402 PHNDTEIANSTPNPKPAASSPETPSAGQQEAKTDQADGPREPPQSARRKRSYKQAVSELD 461
Query: 314 EEKAKAELIMDDDRTVDPLLSKSQSILISTSATASSKKTIEDRNIKNKKSTNNRASSASA 373
EE+ +D + P SK+ S S +T +N+ +++
Sbjct: 462 EEQHL------EDEELQPPRSKTPSSPCPASKVVRPLRTFLHTVQRNQMLMT---PTSAP 512
Query: 374 RLMTSEFLKKSSSKRRTPSTTTSSHYLGTLKVLDQKPSQKQSIEPDRADNIRAAVYQEWL 433
R + F+K+++ R P + + + ++Q +E D+ + +
Sbjct: 513 RSVMKSFIKRNTPLRMDPKEKERQRLENLRRKEEAEQLRRQKVEEDKRRRLEEVKLKRE- 571
Query: 434 EKKNVYLHEMHRIKRIESENLRIQNEQKKAAKREEALASFEAWKAMKEKEAKKIAAKKRL 493
E+ L R+++++ E + Q EQK A E+ + E + +EK KK AAKK
Sbjct: 572 ERLRKVLQARERVEQMKEEKKK-QIEQKFAQIDEKTEKAKEE-RLAEEKAKKKAAAKKME 629
Query: 494 EEKNKKKTEEENAARKGEALQAFEKWKEKKMEYLKEKNRKEREYERAKKQKEEETVAEKK 553
E + ++K EEE AR+ LQ E +E++ + L +K +KE E ER +K E + +AE++
Sbjct: 630 EVEARRKQEEE--ARRLRWLQQEE--EERRHQELLQK-KKEEEQERLRKAAEAKRLAEQR 684
Query: 554 KDNLTAVEKWNEKKEAFFKQKEKEKINEKRKEELKRAEKKDKDKQAINEYEKWLENKEKQ 613
+ E+ +++ +++++ + E+R++E + AE++ + +Q + E+ L+ +EK
Sbjct: 685 EQ-----ERREQERREQERREQERREQERREQERQLAEQERRREQERLQAERELQEREKA 739
Query: 614 ERIERKQKKR 623
R++++Q +R
Sbjct: 740 LRLQKEQLQR 749
Score = 54.3 bits (129), Expect = 3e-07
Identities = 85/423 (20%), Positives = 167/423 (39%), Gaps = 60/423 (14%)
Query: 148 PKPRILSIKSTSSAENNSLDTDDHFKPSPRPRSMLKKKSHMEEKDGLEDKETALSEELEL 207
PKP S T SA TD P P+S +K+S+ + L++++ EEL+
Sbjct: 415 PKPAASS-PETPSAGQQEAKTDQADGPREPPQSARRKRSYKQAVSELDEEQHLEDEELQP 473
Query: 208 -HSAPSSLPTPNGIQLEAEKKAFSENLDPEDSCLT--SLASSSLKQILGDSFSPGSEGNA 264
S S P P ++ + F + +T S S +K +
Sbjct: 474 PRSKTPSSPCPAS-KVVRPLRTFLHTVQRNQMLMTPTSAPRSVMKSFI-------KRNTP 525
Query: 265 SGKDPNEEITENHNSLKSDENKENSFSADHVTTAVEKSKESQVTADDLEEEKAKAELIMD 324
DP E+ + +L+ E E VE+ K ++ L+ E+ +++
Sbjct: 526 LRMDPKEKERQRLENLRRKEEAEQLRRQK-----VEEDKRRRLEEVKLKREERLRKVLQA 580
Query: 325 DDRTVDPLLSKSQSILISTSATASSKKTIEDRNIKNKKSTNNRASSASARLMTSEFLKKS 384
+R K + I + + ++ + +K+ + +A+ ++ E +K
Sbjct: 581 RERVEQMKEEKKKQIEQKFAQIDEKTEKAKEERLAEEKA---KKKAAAKKMEEVEARRKQ 637
Query: 385 SSKRRTPSTTTSSHYLGTLKVLDQKPSQKQSIEPDRADNIRAAVYQEWLEKKNVYLHEMH 444
+ R L+ L Q+ +++ +QE L+KK E
Sbjct: 638 EEEARR------------LRWLQQEEEERR--------------HQELLQKKKEEEQERL 671
Query: 445 RIKRIESENLRIQNEQKKAA--KREEALASFEAWKAMKEKEAKKIAAKKRLEEKNKKKTE 502
R K E++ L Q EQ++ +RE+ E + + ++ +++A ++R E+ + + E
Sbjct: 672 R-KAAEAKRLAEQREQERREQERREQERREQERREQERREQERQLAEQERRREQERLQAE 730
Query: 503 EENAARKGEALQAFEKWKEKKMEYLKEKNRKE-------REYERAKKQKEEETVAEKKKD 555
E R+ +A KE+ L+EK +KE R+ + +++K +E K
Sbjct: 731 RELQERE----KALRLQKEQLQRELEEKKKKEEQQRLAERQLQEEQEKKAKEAAGASKAL 786
Query: 556 NLT 558
N+T
Sbjct: 787 NVT 789
Score = 52.4 bits (124), Expect = 1e-06
Identities = 39/150 (26%), Positives = 77/150 (51%), Gaps = 11/150 (7%)
Query: 492 RLEEKNKKKTEEENAARKGEA----LQAFEKWKEKKMEYLKEKNRKER------EYERAK 541
R++ K K++ EN RK EA Q E+ K +++E +K K R+ER ER +
Sbjct: 527 RMDPKEKERQRLENLRRKEEAEQLRRQKVEEDKRRRLEEVKLK-REERLRKVLQARERVE 585
Query: 542 KQKEEETVAEKKKDNLTAVEKWNEKKEAFFKQKEKEKINEKRKEELKRAEKKDKDKQAIN 601
+ KEE+ ++K + K+E ++K K+K K+ EE++ K++++ + +
Sbjct: 586 QMKEEKKKQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLR 645
Query: 602 EYEKWLENKEKQERIERKQKKRHSFLESEA 631
++ E + QE +++K+++ L A
Sbjct: 646 WLQQEEEERRHQELLQKKKEEEQERLRKAA 675
>gi|102467235 inner centromere protein antigens 135/155kDa isoform 1
[Homo sapiens]
Length = 918
Score = 82.0 bits (201), Expect = 2e-15
Identities = 104/494 (21%), Positives = 223/494 (45%), Gaps = 47/494 (9%)
Query: 150 PRILSIKSTSSAENNSLDTDDHFKPSPRPRSMLKKKSHMEEKDGLEDK-----------E 198
P S + S ++ S+ SP P+ + +K S + +++ + + E
Sbjct: 287 PDNFSTPTGSRTDSQSVRHSPIAPSSPSPQVLAQKYSLVAKQESVVRRASRRLAKKTAEE 346
Query: 199 TALSEELELHSAPSSLPTPNGIQLEAEKKAFSENLDP-EDSCLTSLASSSLKQILGDSFS 257
A S + HS L + +E +K SE +P E++ + A + + G++
Sbjct: 347 PAASGRIICHSYLERL-----LNVEVPQKVGSEQKEPPEEAEPVAAAEPEVPENNGNNSW 401
Query: 258 PGSEGNASGKDPNEEIT----ENHNSLKSDENKENSFSADHVTTAVEKSKESQVTADDLE 313
P ++ + PN + E ++ + + + + + + + + +L+
Sbjct: 402 PHNDTEIANSTPNPKPAASSPETPSAGQQEAKTDQADGPREPPQSARRKRSYKQAVSELD 461
Query: 314 EEKAKAELIMDDDRTVDPLLSKSQSILISTSATASSKKTIEDRNIKNKKSTNNRASSASA 373
EE+ +D + P SK+ S S +T +N+ +++
Sbjct: 462 EEQHL------EDEELQPPRSKTPSSPCPASKVVRPLRTFLHTVQRNQMLMT---PTSAP 512
Query: 374 RLMTSEFLKKSSSKRRTPSTTTSSHYLGTLKVLDQKPS----QKQSIEPDRADNIRAAVY 429
R + F+K+++ R P + L+ L +K ++Q +E D+ +
Sbjct: 513 RSVMKSFIKRNTPLRMDPKCSFVEKERQRLENLRRKEEAEQLRRQKVEEDKRRRLEEVKL 572
Query: 430 QEWLEKKNVYLHEMHRIKRIESENLRIQNEQKKAAKREEALASFEAWKAMKEKEAKKIAA 489
+ E+ L R+++++ E + Q EQK A E+ + E + +EK KK AA
Sbjct: 573 KRE-ERLRKVLQARERVEQMKEEKKK-QIEQKFAQIDEKTEKAKEE-RLAEEKAKKKAAA 629
Query: 490 KKRLEEKNKKKTEEENAARKGEALQAFEKWKEKKMEYLKEKNRKEREYERAKKQKEEETV 549
KK E + ++K EEE AR+ LQ E +E++ + L +K +KE E ER +K E + +
Sbjct: 630 KKMEEVEARRKQEEE--ARRLRWLQQEE--EERRHQELLQK-KKEEEQERLRKAAEAKRL 684
Query: 550 AEKKKDNLTAVEKWNEKKEAFFKQKEKEKINEKRKEELKRAEKKDKDKQAINEYEKWLEN 609
AE+++ E+ +++ +++++ + E+R++E + AE++ + +Q + E+ L+
Sbjct: 685 AEQREQ-----ERREQERREQERREQERREQERREQERQLAEQERRREQERLQAERELQE 739
Query: 610 KEKQERIERKQKKR 623
+EK R++++Q +R
Sbjct: 740 REKALRLQKEQLQR 753
Score = 51.6 bits (122), Expect = 2e-06
Identities = 83/423 (19%), Positives = 166/423 (39%), Gaps = 56/423 (13%)
Query: 148 PKPRILSIKSTSSAENNSLDTDDHFKPSPRPRSMLKKKSHMEEKDGLEDKETALSEELEL 207
PKP S T SA TD P P+S +K+S+ + L++++ EEL+
Sbjct: 415 PKPAASS-PETPSAGQQEAKTDQADGPREPPQSARRKRSYKQAVSELDEEQHLEDEELQP 473
Query: 208 -HSAPSSLPTPNGIQLEAEKKAFSENLDPEDSCLT--SLASSSLKQILGDSFSPGSEGNA 264
S S P P ++ + F + +T S S +K + + +
Sbjct: 474 PRSKTPSSPCPAS-KVVRPLRTFLHTVQRNQMLMTPTSAPRSVMKSFIKRNTPLRMDPKC 532
Query: 265 SGKDPNEEITENHNSLKSDENKENSFSADHVTTAVEKSKESQVTADDLEEEKAKAELIMD 324
S + + EN + E VE+ K ++ L+ E+ +++
Sbjct: 533 SFVEKERQRLENLRRKEEAEQLRRQ--------KVEEDKRRRLEEVKLKREERLRKVLQA 584
Query: 325 DDRTVDPLLSKSQSILISTSATASSKKTIEDRNIKNKKSTNNRASSASARLMTSEFLKKS 384
+R K + I + + ++ + +K+ + +A+ ++ E +K
Sbjct: 585 RERVEQMKEEKKKQIEQKFAQIDEKTEKAKEERLAEEKA---KKKAAAKKMEEVEARRKQ 641
Query: 385 SSKRRTPSTTTSSHYLGTLKVLDQKPSQKQSIEPDRADNIRAAVYQEWLEKKNVYLHEMH 444
+ R L+ L Q+ +++ +QE L+KK E
Sbjct: 642 EEEARR------------LRWLQQEEEERR--------------HQELLQKKKEEEQERL 675
Query: 445 RIKRIESENLRIQNEQKKAA--KREEALASFEAWKAMKEKEAKKIAAKKRLEEKNKKKTE 502
R K E++ L Q EQ++ +RE+ E + + ++ +++A ++R E+ + + E
Sbjct: 676 R-KAAEAKRLAEQREQERREQERREQERREQERREQERREQERQLAEQERRREQERLQAE 734
Query: 503 EENAARKGEALQAFEKWKEKKMEYLKEKNRKE-------REYERAKKQKEEETVAEKKKD 555
E R+ +A KE+ L+EK +KE R+ + +++K +E K
Sbjct: 735 RELQERE----KALRLQKEQLQRELEEKKKKEEQQRLAERQLQEEQEKKAKEAAGASKAL 790
Query: 556 NLT 558
N+T
Sbjct: 791 NVT 793
Score = 48.1 bits (113), Expect = 2e-05
Identities = 43/196 (21%), Positives = 92/196 (46%), Gaps = 14/196 (7%)
Query: 439 YLHEMHRIKRIESENLRIQNEQKKAAKREEALASFEAWKAMKEKEAKKIAAKKRLEEKN- 497
+LH + R + + + ++ K KR L + + EKE +++ +R EE
Sbjct: 495 FLHTVQRNQMLMTPTSAPRSVMKSFIKRNTPLR-MDPKCSFVEKERQRLENLRRKEEAEQ 553
Query: 498 --KKKTEEENAARKGEALQAFEKWKEKKMEYLKEKNRKEREYERAKKQKEEETVAEKKKD 555
++K EE+ R E+ K K+ E L++ + ER ++ KEE+ ++K
Sbjct: 554 LRRQKVEEDKRRR-------LEEVKLKREERLRKVLQAR---ERVEQMKEEKKKQIEQKF 603
Query: 556 NLTAVEKWNEKKEAFFKQKEKEKINEKRKEELKRAEKKDKDKQAINEYEKWLENKEKQER 615
+ K+E ++K K+K K+ EE++ K++++ + + ++ E + QE
Sbjct: 604 AQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQEEEERRHQEL 663
Query: 616 IERKQKKRHSFLESEA 631
+++K+++ L A
Sbjct: 664 LQKKKEEEQERLRKAA 679
>gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-like
[Homo sapiens]
Length = 899
Score = 79.3 bits (194), Expect = 1e-14
Identities = 126/630 (20%), Positives = 261/630 (41%), Gaps = 75/630 (11%)
Query: 24 FQDELIRAITARSARQRSSE-YSDDFDSD-EIVSLGDFSDTSADENSVNKKMNDFHISDD 81
F EL RA++A S R + ++ Y ++ + + +SL + +T +E KK N ++
Sbjct: 177 FAGELQRALSAVSTRHKKADRYIEELTKERDALSLELYRNTITNEEL--KKKN----AEL 230
Query: 82 EEKNPSKLLFLKTNKSNGNITKDEPVCAIKNEEEMAPDGCEDIVVKSFSESQNKDEEFEK 141
+EK P ++ KS + E +K + E A + + E + EE +
Sbjct: 231 QEKLP----LAESEKSEIQLNVKE----LKRKLERAKFLLPQVQTNTLQEEMWRQEEELR 282
Query: 142 DKIKMKPKPRILSIKSTSSAENNSLDTDDHFKPSPRPRSMLKKKSHMEEKDGLEDKETAL 201
++ K +I + + L + + ++K E++ L ++E L
Sbjct: 283 EQEK-----KIRKQEEKMWRQEERLREQEGKMREQEEKMWRQEKRLREQEKELREQEKEL 337
Query: 202 SEELELHSAPSSLPTPNGIQLEAEKKAFSENLDPEDSCLTSLASSSLKQILGDSFSPGSE 261
E+ EL + E E+K + E+ ++ L + E
Sbjct: 338 REQKELREQEEQMQEQEEKMWEQEEKMREQ----EEKMWRQ------EERLWEQEKQMRE 387
Query: 262 GNASGKDPNEEITENHNSLKSDENKENSFSADHVTTAVEKSKESQVTADDLEEEKAKAEL 321
+D E + E L+ E +E + + VEK +E + + ++ + + E
Sbjct: 388 QEQKMRDQEERMWEQDERLR--EKEERMREQEKMWEQVEKMREEKKMQEQEKKTRDQEEK 445
Query: 322 IMDDDRTVDPLLSKSQSILISTSATASSKKTIEDRNI---KNKKSTNNRASSASARLMTS 378
+ +++R + K T K ++ N+ + K+ R +L
Sbjct: 446 MQEEERIRER--EKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQ 503
Query: 379 EFLKKSSSKRRTPSTTTSSHYLGTLKVLDQKPSQKQSIEPDRADNIRAAVYQEWLEKKNV 438
E +++ K K+ DQ+ Q + R + +R Q W +++ +
Sbjct: 504 EKMQEQEEKIWEQEE----------KIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKM 553
Query: 439 YLHEMHRIKRIESENLRIQNEQKKAAKREEALASFEAWKAMKEKEAKKIAAKKRLEEKNK 498
E + E + Q ++KK +EE M+E+E + KK EE+
Sbjct: 554 RDQEQKMWDQEERMEKKTQEQEKKTWDQEEK---------MREEERMREREKKMREEEEM 604
Query: 499 KKTEEENAARKGEALQAFEK--WK-EKKMEYLKEK--NRKEREYERAKKQKEEETVAEKK 553
+ +EE + E +Q E+ W+ E+KM+ +EK ++E+ +E+ +K E++ + E+K
Sbjct: 605 MREQEEKMQEQEEKMQEQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEKMWEQQRLPEQK 664
Query: 554 K-----DNLTAVEKWNEKKEAFFKQKEKEKINEKRKEELKRAEK-------KDKDKQAIN 601
+ + + EK E++E ++Q++ EK ++++++ EK ++++K+
Sbjct: 665 EKLWEHEKMQEQEKMQEQEEKIWEQEKMEKKTQEQEKKTWDQEKMREEESMREREKKMRE 724
Query: 602 EYEKWLENKEK-QERIERKQKKRHSFLESE 630
E E E +EK QE+ E+ Q++ E E
Sbjct: 725 EEEMMREQEEKMQEQEEKMQEQEEEMWEQE 754
Score = 72.4 bits (176), Expect = 1e-12
Identities = 106/504 (21%), Positives = 212/504 (42%), Gaps = 70/504 (13%)
Query: 189 EEKDGLEDKETALSEELELHSAPSSLPTPNGIQLE--------AEKKAFSENLDPEDSCL 240
EEK + AL E+E + T +LE A +K NL S
Sbjct: 81 EEKKASHQHQEALRREIEAQDHTIRILTCQKTELETALYYSQDAARKFEDGNLGTPSSFN 140
Query: 241 TSLASSSLKQILG---DSFSPGSEGNASGKDPNEEITENHNSLKSDENKENSFSADHVTT 297
+L+ + LG S PG + +G+ H+S + + SA V+T
Sbjct: 141 LALSQAFRGSPLGCVSTSLIPGESKDLAGR--------LHHSWHFAGELQRALSA--VST 190
Query: 298 AVEKSKESQVTADDLEEEKAKAELIMDDDRTVDPLLSKSQSILISTSATASSKKTIEDRN 357
+ K++ ++L +E+ L + + + L K + L A S+K+ N
Sbjct: 191 ---RHKKADRYIEELTKERDALSLELYRNTITNEELKKKNAELQEKLPLAESEKSEIQLN 247
Query: 358 IKNKKSTNNRASSASARLMTS----------EFLKKSSSKRRTPSTTTSSHYLGTLKVLD 407
+K K RA ++ T+ E L++ K R + ++ +
Sbjct: 248 VKELKRKLERAKFLLPQVQTNTLQEEMWRQEEELREQEKKIRKQE---EKMWRQEERLRE 304
Query: 408 QKPSQKQSIEPDRADNIRAAVYQEWLEKKNVYLHEMHRIKRIESE-----------NLRI 456
Q+ ++ E R ++ L ++ L E ++ E + ++
Sbjct: 305 QEGKMREQEEKMWRQEKRLREQEKELREQEKELREQKELREQEEQMQEQEEKMWEQEEKM 364
Query: 457 QNEQKKAAKREEALASFEAWKAMKEKEAKKIAAKKRLEEKNKKKTEEENAARKGEAL--Q 514
+ +++K ++EE L +E K M+E+E K ++R+ E++++ E+E R+ E + Q
Sbjct: 365 REQEEKMWRQEERL--WEQEKQMREQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQ 422
Query: 515 AFEKWKEKKMEYLKEKNR--------KEREYERAKKQKEEETVAEKKKDNLTAVEK--WN 564
+ +EKKM+ ++K R +ER ER KK +EEE ++++ + E+ W
Sbjct: 423 VEKMREEKKMQEQEKKTRDQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWE 482
Query: 565 EKKEAFFKQK---EKEKINEKRK-----EELKRAEKKDKDKQAINEYEKWLENKEKQERI 616
++++ + +Q+ +KEK+ E+ K E++ E+K +D++ + EK + +EK
Sbjct: 483 QEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQ 542
Query: 617 ERKQKKRHSFLESEALPPWSPPSR 640
E + ++ + + W R
Sbjct: 543 EDQMWEQEEKMRDQEQKMWDQEER 566
Score = 67.8 bits (164), Expect = 3e-11
Identities = 60/238 (25%), Positives = 124/238 (52%), Gaps = 22/238 (9%)
Query: 406 LDQKPSQKQSIEPDRADNIRAAVYQEWLEKKNVYLHEMHRIK--RIESENLRIQNEQKKA 463
+++K +++ D+ + +R EKK EM R + +++ + ++Q +++K
Sbjct: 567 MEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEKM 626
Query: 464 AKREEALASFEA--WKAMKE--KEAKKIAAKKRLEEKNKKKTEEENAARKGEALQAFEK- 518
++EE + E W+ ++ ++ +K+ ++RL E+ +K E E + + + EK
Sbjct: 627 WEQEEKMQEQEEKMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKMQEQEEKI 686
Query: 519 WKEKKME----------YLKEKNRKEREY-ERAKKQKEEETVAEKKKDNL-TAVEKWNEK 566
W+++KME + +EK R+E ER KK +EEE + ++++ + EK E+
Sbjct: 687 WEQEKMEKKTQEQEKKTWDQEKMREEESMREREKKMREEEEMMREQEEKMQEQEEKMQEQ 746
Query: 567 KEAFFKQKEKE-KINEKRKEELKRAEKKDK--DKQAINEYEKWLENKEKQERIERKQK 621
+E ++Q+EK + EK E+ + E+K+K + + + E EK E +EK E K +
Sbjct: 747 EEEMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKIWEQEEKMRDQEEKMR 804
Score = 57.8 bits (138), Expect = 3e-08
Identities = 46/204 (22%), Positives = 103/204 (50%), Gaps = 19/204 (9%)
Query: 434 EKKNVYLHE-MHRIKRIESENLRIQNEQKKAAKREEALASFEAWKAMKEKEAKKIAAKKR 492
+K+ ++ HE M ++++ + +I ++K K +E + M+E+E+ + KK
Sbjct: 663 QKEKLWEHEKMQEQEKMQEQEEKIWEQEKMEKKTQEQEKKTWDQEKMREEESMREREKKM 722
Query: 493 LEEKNKKKTEEENAARKGEALQAFEKWKEKKMEYLKEKNRKEREYERAKKQKEEETVAEK 552
EE+ + +EE + E +Q E+ ++ E + E+ K E +R +QKE+ EK
Sbjct: 723 REEEEMMREQEEKMQEQEEKMQEQEEEMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEK 782
Query: 553 KKDNLTAVEKWNEKKEAFFKQKEKEKINEKR----KEELKRAEKK----------DKDKQ 598
++ EK E++E Q+EK + E++ +E+++ E+K ++K
Sbjct: 783 MQEQ----EKIWEQEEKMRDQEEKMRGQEEKMRGQEEKMRGQEEKMWGQEEKMWGQEEKM 838
Query: 599 AINEYEKWLENKEKQERIERKQKK 622
E + W + ++ +E+++ +++K
Sbjct: 839 WGQEEKMWGQEEKMEEKMQGQEEK 862
Score = 53.5 bits (127), Expect = 6e-07
Identities = 42/182 (23%), Positives = 98/182 (53%), Gaps = 10/182 (5%)
Query: 459 EQKKAAKREEALASFEAWKAMK--EKEAKKIAAKKRLEEKNK---KKTEEENAARKGEAL 513
EQ++ +++E L E + + +++ +KI ++++E+K + KKT ++ R+ E++
Sbjct: 656 EQQRLPEQKEKLWEHEKMQEQEKMQEQEEKIWEQEKMEKKTQEQEKKTWDQEKMREEESM 715
Query: 514 QAFEKWKEKKMEYLKEKNRKEREYERAKKQKEEETVAEKKKDNLTAVEKWNEKKEAFFKQ 573
+ EK ++ E ++E+ K +E E +K +E+E ++++ + E+ +++ +Q
Sbjct: 716 REREKKMREEEEMMREQEEKMQEQE--EKMQEQEEEMWEQEEKMWEQEEKMWEQQRLPEQ 773
Query: 574 KEKEKINEKRKEELKRAEKKDKDKQAINEYEKWLENKEKQERIERKQKKRHSFLESEALP 633
KEK +EK +E+ K E+++K + ++ EK +EK E K + + + +
Sbjct: 774 KEKLWEHEKMQEQEKIWEQEEKMR---DQEEKMRGQEEKMRGQEEKMRGQEEKMWGQEEK 830
Query: 634 PW 635
W
Sbjct: 831 MW 832
Score = 49.3 bits (116), Expect = 1e-05
Identities = 43/202 (21%), Positives = 110/202 (54%), Gaps = 12/202 (5%)
Query: 404 KVLDQKPSQKQSIEPDRADNIRAAVYQEW-LEKKNVYLHEMHRIKRIESENLRIQNEQKK 462
K+ +Q+ +K++ E ++ + + +E + ++ + E + R + E ++Q +++K
Sbjct: 685 KIWEQEKMEKKTQEQEKKTWDQEKMREEESMREREKKMREEEEMMREQEE--KMQEQEEK 742
Query: 463 AAKREEALASFEAWKAMKEKEAKKIAAKKRLEEKNKKKTEEENAARKGEALQAFEKWK-- 520
++EE + +E + M E+E +K+ ++RL E+ +K E E + + + EK +
Sbjct: 743 MQEQEEEM--WEQEEKMWEQE-EKMWEQQRLPEQKEKLWEHEKMQEQEKIWEQEEKMRDQ 799
Query: 521 EKKMEYLKEKNRKEREYERAKKQK----EEETVAEKKKDNLTAVEKWNEKKEAFFKQKEK 576
E+KM +EK R + E R +++K EE+ +++K + W ++++ K + +
Sbjct: 800 EEKMRGQEEKMRGQEEKMRGQEEKMWGQEEKMWGQEEKMWGQEEKMWGQEEKMEEKMQGQ 859
Query: 577 EKINEKRKEELKRAEKKDKDKQ 598
E+ +++E+++ E+K ++++
Sbjct: 860 EEKMREQEEKMRGQEEKMREQE 881
>gi|44680105 caldesmon 1 isoform 1 [Homo sapiens]
Length = 793
Score = 78.6 bits (192), Expect = 2e-14
Identities = 99/509 (19%), Positives = 216/509 (42%), Gaps = 83/509 (16%)
Query: 137 EEFEKDKIKMKPKPRILSIKSTSSAENNSLDTDDHFKPSPRPRSMLKKKSHMEEKDGLED 196
++FE+ + + K + +++ A + D ++ R R+ ++ +E++ L
Sbjct: 2 DDFERRRELRRQKREEMRLEAERIAYQRNDDDEEEAARERRRRARQERLRQKQEEESLGQ 61
Query: 197 KETALSEELELHSAPSSLP------TPNGIQLEAE----------------KKAFSENLD 234
+++++E++ A +S+P T Q+E + +K E L+
Sbjct: 62 ----VTDQVEVN-AQNSVPDEEAKTTTTNTQVEGDDEAAFLERLARREERRQKRLQEALE 116
Query: 235 PEDSCLTSLASSSLKQILGDSFSPGSEGNASGKDPNEEITENHNSLKSDENKENSFSADH 294
+ ++ +SL + +E + K+ E + ++ E S+ +
Sbjct: 117 RQKEFDPTITDASLSLPSRRMQNDTAENETTEKEEKSESRQERYEIEETETVTKSYQKND 176
Query: 295 VTTAVEKSKESQVTADDLEEEKAKAELIMDDDRTVDPLLSKSQSILISTSATASSKKTIE 354
A E KE + ++ EEEK K I ++ +++ T S ++T+
Sbjct: 177 WRDAEENKKEDKEKEEE-EEEKPKRGSIGENQ----------VEVMVEEKTTESQEETVV 225
Query: 355 DRNIKNKKSTNNRASSASARLMTSEFLKKSSSKRRTPSTTTSSHYLGTLKVLDQKPSQKQ 414
++KN + ++ K +R S S H + ++ +++
Sbjct: 226 -MSLKNGQISSEEP--------------KQEEEREQGSDEISHHEKMEEEDKERAEAERA 270
Query: 415 SIEPDRADNIRAAVYQEWLEKKNVYLHEMHRIKRIESENLRIQNEQKKAAKREEALASFE 474
+E + + I+A + K+I E RI+ E+K AA+ E + E
Sbjct: 271 RLEAEERERIKA-----------------EQDKKIADERARIEAEEKAAAQERERREAEE 313
Query: 475 AWKAMKEKEAKKIAAKKRLEEKNKKKTEEENAARKGEALQAFEKWKEKKMEYLKEKNRKE 534
+ M+E+E + ++R++E+ K+ EE ++ E A E+ + K +E+ R
Sbjct: 314 R-ERMREEEKRAAEERQRIKEEEKRAAEERQRIKEEEKRAAEERQRIK-----EEEKRAA 367
Query: 535 REYERAKKQKEEETVAEKKKDNLTAVEKWNEKKEAFFKQKEK-EKINEKRKEELKRAEKK 593
E +RA+ ++EE+ E++K N ++ EKK A + K K EK+ +K + + +K
Sbjct: 368 EERQRARAEEEEKAKVEEQKRN----KQLEEKKHAMQETKIKGEKVEQKIEGKWVNEKKA 423
Query: 594 DKDKQAINEYEKWLENKEKQERIERKQKK 622
+DK +K + +EK +++ K++K
Sbjct: 424 QEDKLQTAVLKK--QGEEKGTKVQAKREK 450
Score = 70.9 bits (172), Expect = 4e-12
Identities = 108/506 (21%), Positives = 209/506 (41%), Gaps = 78/506 (15%)
Query: 123 DIVVKSFSES------QNKDEEFEKDKIKMKPKPRILSI-----------KSTSSAE--- 162
+ V KS+ ++ +NK E+ EK++ + + KP+ SI K+T S E
Sbjct: 166 ETVTKSYQKNDWRDAEENKKEDKEKEE-EEEEKPKRGSIGENQVEVMVEEKTTESQEETV 224
Query: 163 -----NNSLDTDDHFKPSPRPRSMLKKKSHMEEKDGLEDKETALSEELELHSAPSSLPTP 217
N + +++ + R + + H EK EDKE A +E L +
Sbjct: 225 VMSLKNGQISSEEPKQEEEREQGSDEISHH--EKMEEEDKERAEAERARLEAEERER--- 279
Query: 218 NGIQLEAEKKAFSEN--LDPEDSCLTS---LASSSLKQILGDSFSPGSEGNASGKDPNEE 272
I+ E +KK E ++ E+ + ++ + + +E K+ +
Sbjct: 280 --IKAEQDKKIADERARIEAEEKAAAQERERREAEERERMREEEKRAAEERQRIKEEEKR 337
Query: 273 ITENHNSLKSDENKENSFSADHVTTAVEKSKESQVTADDLEEEKAKAELIMDDDRTVDPL 332
E +K +E K + + +++ E + A EEEKAK E + + L
Sbjct: 338 AAEERQRIKEEE-KRAAEERQRIKEEEKRAAEERQRARAEEEEKAKVE----EQKRNKQL 392
Query: 333 LSKSQSILISTSATASSKKTIEDRNIKNKKSTNNRASSASARLMTSEFLKKSSSKRRTPS 392
K ++ + ++ IE + + KK+ ++ +A + E K +KR
Sbjct: 393 EEKKHAMQETKIKGEKVEQKIEGKWVNEKKAQEDKLQTAVLKKQGEEKGTKVQAKRE--- 449
Query: 393 TTTSSHYLGTLKVLDQKPS-QKQSIEPDRADNIRAAVYQEWLEKKNVYLHEMHRIKRIES 451
K+ + KP+ +K+ I+ ++ + E E+ ++ ++S
Sbjct: 450 -----------KLQEDKPTFKKEEIKDEKIKKDK-----EPKEEVKSFMDRKKGFTEVKS 493
Query: 452 ENLRIQNEQKKAAKREEALASFEAWKAMKEKE-AKKIAAKKRLEEKNKKKTEEENAARKG 510
+N + K + + A KE E A ++ A KRLEE +++ E E+
Sbjct: 494 QNGEFMTHKLKHTENTFSRPGGRASVDTKEAEGAPQVEAGKRLEELRRRRGETES----- 548
Query: 511 EALQAFEKWKEKKMEYLKEKNRKEREYERAKKQKEEETVAEKKKDNLTAVEKWNEKKEAF 570
+ FEK K+K+ E E +++ E +K EEE K+++ A K E++E
Sbjct: 549 ---EEFEKLKQKQQEAALELEELKKKREERRKVLEEEEQRRKQEE---ADRKLREEEE-- 600
Query: 571 FKQKEKEKINEKRKEELKRAEKKDKD 596
K++ KE+I +R E ++ +K +D
Sbjct: 601 -KRRLKEEIERRRAEAAEKRQKMPED 625
>gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-like
[Homo sapiens]
Length = 828
Score = 77.0 bits (188), Expect = 5e-14
Identities = 55/200 (27%), Positives = 110/200 (55%), Gaps = 9/200 (4%)
Query: 437 NVYLHEMHRIKR-IESENLRIQNEQKKAAKREEALASFEAWKAMKEKEAKKIAAKKRLEE 495
N EM R + + + +I+ +++K ++EE L E M+E+E K +KRL E
Sbjct: 230 NTLQEEMWRQEEELREQEKKIRKQEEKMWRQEERLREQEG--KMREQEEKMRRQEKRLRE 287
Query: 496 KNKKKTEEENAARKGEALQAFEKWKEKKMEYLKEKNRKEREYERAKKQKEEETVAEKKKD 555
+ K+ E+E R+ + L+ E+ +++ E + E+ K RE E K ++EE + E++K
Sbjct: 288 QEKELREQEKELREQKKLREQEEQMQEQEEKMWEQEEKMREQEE-KMWRQEERLWEQEKQ 346
Query: 556 NLTAVEKWNEKKEAFFKQKEKEKINEKR---KEELKRAEKKDKDKQAINEYEKWLENKEK 612
+K +++E ++Q E+ + E+R +E++ E+K ++++ I E EK + +E+
Sbjct: 347 MREQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQEEKMQEEERIREREKKMREEEE 406
Query: 613 --QERIERKQKKRHSFLESE 630
+E+ E+ QK+ + E E
Sbjct: 407 TMREQEEKMQKQEENMWEQE 426
Score = 70.9 bits (172), Expect = 4e-12
Identities = 75/363 (20%), Positives = 167/363 (46%), Gaps = 34/363 (9%)
Query: 303 KESQVTADDLEEEKAKAELIMDDDRTVDPLLSKSQSILISTSATASSKKTIEDRNIKNKK 362
K++ ++L +E+ L + + + L K + L A S+K+ N+K K
Sbjct: 155 KKADRYIEELTKERDALSLELYRNTITNEELKKKNAELQEKLRLAESEKSEIQLNVKELK 214
Query: 363 STNNRASSASARLMTS----------EFLKKSSSKRRTPSTTTSSHYLGTLKVLDQKPSQ 412
RA ++ T+ E L++ K R + ++ +Q+
Sbjct: 215 RKLERAKFLLPQVQTNTLQEEMWRQEEELREQEKKIRKQE---EKMWRQEERLREQEGKM 271
Query: 413 KQSIEPDRADNIRAAVYQEWLEKKNVYLHEMHRIKRIESE-----------NLRIQNEQK 461
++ E R R ++ L ++ L E +++ E + +++ +++
Sbjct: 272 REQEEKMRRQEKRLREQEKELREQEKELREQKKLREQEEQMQEQEEKMWEQEEKMREQEE 331
Query: 462 KAAKREEALASFEAWKAMKEKEAKKIAAKKRLEEKNKKKTEEENAARKGEALQAFEKWKE 521
K ++EE L +E K M+E+E K ++R+ E++++ E+E R+ E + E+ K
Sbjct: 332 KMWRQEERL--WEQEKQMREQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQEE-KM 388
Query: 522 KKMEYLKEKNRKEREYERAKKQKEEETVAEKKKDNLTAVEKWNEKKEAFFKQKEK----E 577
++ E ++E+ +K RE E +++EE+ +K+++N+ E+ +++ +QKEK E
Sbjct: 389 QEEERIREREKKMREEEETMREQEEKM--QKQEENMWEQEEKEWQQQRLPEQKEKLWEQE 446
Query: 578 KINEKRKEELKRAEKKDKDKQAINEYEKWLENKEKQERIERKQKKRHSFLESEALPPWSP 637
K+ E+ +E++ E+K +D++ + EK + +EK E + ++ + + W
Sbjct: 447 KMQEQ-EEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQ 505
Query: 638 PSR 640
R
Sbjct: 506 EER 508
Score = 70.9 bits (172), Expect = 4e-12
Identities = 49/235 (20%), Positives = 120/235 (51%), Gaps = 17/235 (7%)
Query: 404 KVLDQKPSQKQSIEPDRADNIRAAVYQEWLEKKNVYLHEMHRIKRIESENLRIQNEQKKA 463
K+ DQ+ Q + R + +R Q W +++ + E K + E + +++
Sbjct: 461 KIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQ---KMWDQEERMWEQDERLR 517
Query: 464 AKREEALASFEAWKAMKEKEAKKIAAKKRLEEKNKKKTEEENAARKGEALQAFEKWKEKK 523
K E + W+ + +K+ +K+ +E+ KK ++E R+ E ++ EK ++
Sbjct: 518 EKEERMREQKKMWQ-----QEEKMREEKKTQEQEKKTWDQEEKMREEERMREREKKMREE 572
Query: 524 MEYLKEKNRKEREYERAKKQKEEETVAEKKKDNLTAVEKWNEKKEAFFKQKEKEKINEK- 582
E ++E+ K +E E +++EE+ +++K + W E++E ++Q+E++K+ E+
Sbjct: 573 EEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMW-EQEEKMWEQEEEDKMQEQE 631
Query: 583 -----RKEELKRAEKK--DKDKQAINEYEKWLENKEKQERIERKQKKRHSFLESE 630
++E+++ E+K +++++ + EK E +EK + E K +++ ++ +
Sbjct: 632 EMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMREQEEKMQGQ 686
Score = 64.7 bits (156), Expect = 3e-10
Identities = 71/407 (17%), Positives = 175/407 (42%), Gaps = 61/407 (14%)
Query: 278 NSLKSDE-NKENSFSADHVTTAVEKSKESQVTADDLEEEKAKAELIMDDDRTVDPLLSKS 336
N++ ++E K+N+ + + A + E Q+ +L+ + +A+ ++ +T +
Sbjct: 178 NTITNEELKKKNAELQEKLRLAESEKSEIQLNVKELKRKLERAKFLLPQVQTN----TLQ 233
Query: 337 QSILISTSATASSKKTIEDRNIKNKKSTNNRASSASARLMTSEFLKKSSSKR---RTPST 393
+ + +K I + K + R ++ E + KR +
Sbjct: 234 EEMWRQEEELREQEKKIRKQEEKMWRQ-EERLREQEGKMREQEEKMRRQEKRLREQEKEL 292
Query: 394 TTSSHYLGTLKVLDQKPSQKQSIEP---DRADNIRAAVYQEWLEKKNVYLHEMHRIKRIE 450
L K L ++ Q Q E ++ + +R + W +++ ++ E K++
Sbjct: 293 REQEKELREQKKLREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQE----KQMR 348
Query: 451 SENLRIQNEQKKAAKREEALASFEAWKAMKEK---EAKKIAAKKRLEEKNKKKTEEENAA 507
+ ++++++++ +++E L E +EK + +K+ ++R+ E+ KK EEE
Sbjct: 349 EQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQEEKMQEEERIREREKKMREEEETM 408
Query: 508 RKGEAL---QAFEKWKEKKMEYLKEK--NRKEREYERAKKQKEEETVAEKKKDNLTAVEK 562
R+ E Q W++++ E+ +++ +KE+ +E+ K Q++EE + E+++ E
Sbjct: 409 REQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEM 468
Query: 563 WNEKKEAFFKQK-------------------------------------EKEKINEKRKE 585
W ++K+ + ++K EKE+ ++K+
Sbjct: 469 WGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMWEQDERLREKEERMREQKK 528
Query: 586 ELKRAEKKDKDKQAINEYEKWLENKEKQERIERKQKKRHSFLESEAL 632
++ EK ++K+ + +K + +EK ER +++ E E +
Sbjct: 529 MWQQEEKMREEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEM 575
Score = 63.2 bits (152), Expect = 7e-10
Identities = 51/211 (24%), Positives = 110/211 (52%), Gaps = 18/211 (8%)
Query: 430 QEWLEKKNVYLHEMHRI----KRIESENLRIQNEQKKAAKREEALASFEA--WKAMKEKE 483
QE + ++ + E RI K++ E ++ +++K K+EE + E W+ + E
Sbjct: 378 QEKMWEQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPE 437
Query: 484 AK-KIAAKKRLEEKNKKKTEEENAARKGEALQAFEKWKEKKMEYLKEKNRKERE--YERA 540
K K+ +++++E+ +K E+E R E E W ++K + +EK R++ + +E+
Sbjct: 438 QKEKLWEQEKMQEQEEKIWEQEEKIRDQE-----EMWGQEKKMWRQEKMREQEDQMWEQE 492
Query: 541 KKQKEEETVAEKKKDNL-TAVEKWNEKKEAFFKQKEKEKINEKRKEELKRAEKKDKDKQA 599
+K +++E +++ + E+ EK+E +QK+ + EK +EE K E ++K+
Sbjct: 493 EKMRDQEQKMWDQEERMWEQDERLREKEERMREQKKMWQQEEKMREEKKTQE---QEKKT 549
Query: 600 INEYEKWLENKEKQERIERKQKKRHSFLESE 630
++ EK E + +ER ++ +++ E E
Sbjct: 550 WDQEEKMREEERMREREKKMREEEEMMREQE 580
Score = 62.4 bits (150), Expect = 1e-09
Identities = 57/247 (23%), Positives = 112/247 (45%), Gaps = 35/247 (14%)
Query: 431 EWLEKKNVYLHEMHRIKRIES---ENLRIQNEQKKAAKREEALASFEAW-----KAMKEK 482
E L +K + E ++ + E E + Q ++KK +EE + E K +E+
Sbjct: 514 ERLREKEERMREQKKMWQQEEKMREEKKTQEQEKKTWDQEEKMREEERMREREKKMREEE 573
Query: 483 EAKKIAAKKRLEEKNKKKTEEENAARKGEALQAFEK--WKEKKMEYLKEKNRKEREYE-- 538
E + +K E++ K + +EE + E +Q E+ W++++ + +E+ K +E E
Sbjct: 574 EMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEEDKMQEQEEM 633
Query: 539 ----RAKKQKEEETVAEKKKDNLTAVEKWNEKKEAFFKQKEKEKINEKRKEELKRAEKKD 594
K Q++EE + E+++ EK E++E Q+EK + E++ + + ++
Sbjct: 634 MWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMREQEEKMQGQEEKMREQ 693
Query: 595 KDKQAINEYEKW----------------LENKEKQERIERKQKKRHSFL---ESEALPPW 635
++K E + W E +EK+ERI +++K L E P
Sbjct: 694 EEKMRGQEEKMWGQEEKMWGQEEKMWGQEEMREKEERIRDQKEKMQERLPEHEERCSEPC 753
Query: 636 SPPSRTV 642
PPS+ +
Sbjct: 754 LPPSKVL 760
Score = 52.8 bits (125), Expect = 1e-06
Identities = 42/213 (19%), Positives = 112/213 (52%), Gaps = 11/213 (5%)
Query: 404 KVLDQKPSQKQSIEP-DRADNIRAAVYQEWLEKKNVYLHEMHRIK--RIESENLRIQNEQ 460
K+ ++K +Q+Q + D+ + +R EKK EM R + +++ + +++ ++
Sbjct: 535 KMREEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMREQE 594
Query: 461 KKAAKREEALASFEA--W----KAMKEKEAKKIAAKKRL--EEKNKKKTEEENAARKGEA 512
+K ++EE + E W K +++E K+ ++ + E++ K + +EE + E
Sbjct: 595 EKMWEQEEKMQEQEEKMWEQEEKMWEQEEEDKMQEQEEMMWEQEEKMQEQEEKMWEQEEK 654
Query: 513 LQAFEKWKEKKMEYLKEKNRKEREYERAKKQKEEETVAEKKKDNLTAVEKWNEKKEAFFK 572
++ E+ ++ E ++ + K RE E + +EE+ +++K + W ++++ + +
Sbjct: 655 MREQEEKMREQEEKMQGQEEKMREQEEKMQGQEEKMREQEEKMRGQEEKMWGQEEKMWGQ 714
Query: 573 QKEKEKINEKRKEELKRAEKKDKDKQAINEYEK 605
+++ E R++E + ++K+K ++ + E+E+
Sbjct: 715 EEKMWGQEEMREKEERIRDQKEKMQERLPEHEE 747
Score = 30.0 bits (66), Expect = 6.9
Identities = 21/73 (28%), Positives = 37/73 (50%), Gaps = 11/73 (15%)
Query: 557 LTAVEKWNEKKEAFFKQKEKEK--------INEKRKEELKRAEKKDKDKQAINEYEK--- 605
L+AV W++K + + ++ KE+ N EELK+ + ++K + E EK
Sbjct: 147 LSAVSTWHKKADRYIEELTKERDALSLELYRNTITNEELKKKNAELQEKLRLAESEKSEI 206
Query: 606 WLENKEKQERIER 618
L KE + ++ER
Sbjct: 207 QLNVKELKRKLER 219
>gi|55741709 RNA binding motif protein 25 [Homo sapiens]
Length = 843
Score = 75.9 bits (185), Expect = 1e-13
Identities = 90/396 (22%), Positives = 176/396 (44%), Gaps = 48/396 (12%)
Query: 275 ENHNSLKSDENKENSFSADHVTTAVEKSKESQVTADDLEEEK-AKAELIMDDDRTVDPLL 333
++H LK+ EN EN TT V S+ +D L + AK L++ R V
Sbjct: 69 KDHPGLKAKENDENCGP----TTTVFVGNISEKASDMLIRQLLAKCGLVLSWKR-VQGAS 123
Query: 334 SKSQSILI----STSATASSKKTIEDRNIKNKKSTNNRASSASARLMTSEFLKKSSSKRR 389
K Q+ +T + + + D I KK + A+L + KK+S+
Sbjct: 124 GKLQAFGFCEYKEPESTLRALRLLHDLQIGEKKLLVKVDAKTKAQLDEWKAKKKASNGNA 183
Query: 390 TPSTTTSSH--------------YLGTLKVLDQKPSQKQSIEPDRADNIRAAVYQEWLEK 435
P T T+ G ++VL ++ S + + +D+ +E +K
Sbjct: 184 RPETVTNDDEEALDEETKRRDQMIKGAIEVLIREYSSELNAPSQESDSHPRKKKKE--KK 241
Query: 436 KNVY------------LHEMHRIKRIESENLRIQNEQKKAAKREEALASFEAWKAMKEKE 483
++++ L I IE E + ++ +K + E K KEKE
Sbjct: 242 EDIFRRFPVAPLIPYPLITKEDINAIEMEEDKRDLISREISKFRDTHKKLEEEKGKKEKE 301
Query: 484 AKKIAAKKRLEEKNKKKTEEENAARKGEALQAFEKWKEKKMEYLKEKNR-----KEREYE 538
++I K+R E + +++ E E R+ E + E+ KEK+ E +E++R KER+ +
Sbjct: 302 RQEIE-KERRERERERERERERREREREREREREREKEKERERERERDRDRDRTKERDRD 360
Query: 539 RAKKQ---KEEETVAEKKKDNLTAVEKWNEKKEAFFKQKEKEKINEKRKEELKRAEKKDK 595
R +++ ++ E +++ KD + EK +++ +++E+E+ E R+ E +R ++++
Sbjct: 361 RDRERDRDRDRERSSDRNKDRSRSREKSRDRERERERERERERERE-RERERERERERER 419
Query: 596 DKQAINEYEKWLENKEKQERIERKQKKRHSFLESEA 631
+++ E +K + +E +E ++K E EA
Sbjct: 420 EREREREKDKKRDREEDEEDAYERRKLERKLREKEA 455
Score = 53.9 bits (128), Expect = 4e-07
Identities = 57/249 (22%), Positives = 113/249 (45%), Gaps = 17/249 (6%)
Query: 407 DQKPSQKQSIEPDRADNIRAAVYQEWLEKKNVYLHEMHRIKRIESENLRIQNEQKKAAKR 466
D+ + +S E R D R + E++ E R + E E R + + KK +
Sbjct: 376 DRNKDRSRSREKSR-DREREREREREREREREREREREREREREREREREREKDKKRDRE 434
Query: 467 EEALASFEAWKAMKEKEAKKIAAKKRLE-----EKNKKKTEEENAARKGEALQAFEKWKE 521
E+ ++E K ++ K+ A ++RL+ E+ K + E+ A R+ E + K +
Sbjct: 435 EDEEDAYERRKLERKLREKEAAYQERLKNWEIRERKKTREYEKEAEREEERRREMAKEAK 494
Query: 522 KKMEYLKE--KNRKEREYERAK------KQKEEETVAEKKKDNLTAVEKWNEKKEAFFKQ 573
+ E+L++ +R + +Y R + +E+E A+++ D E+ E ++ +
Sbjct: 495 RLKEFLEDYDDDRDDPKYYRGSALQKRLRDREKEMEADER-DRKREKEELEEIRQRLLAE 553
Query: 574 KEKEKINEKRKEELKRAEKKDKDKQAINEYEKWLENKEKQERIERKQKKRHSFLESEALP 633
+ E ++ E + AE++ + Q E E E +EKQE+ E++++ E E P
Sbjct: 554 GHPDPDAELQRME-QEAERR-RQPQIKQEPESEEEEEEKQEKEEKREEPMEEEEEPEQKP 611
Query: 634 PWSPPSRTV 642
P R +
Sbjct: 612 CLKPTLRPI 620
>gi|239749449 PREDICTED: hypothetical protein [Homo sapiens]
Length = 275
Score = 74.7 bits (182), Expect = 2e-13
Identities = 48/170 (28%), Positives = 97/170 (57%), Gaps = 10/170 (5%)
Query: 457 QNEQKKAAKREEALASFEAWKAMKEKEAKKIAAKKRLEEKNKKKTE---EENAARKGEAL 513
Q E ++ +R E E K +EKE K+ KK E+K +KK E E RK
Sbjct: 31 QRESERKKERRER----EKRKREREKERKRERGKK--EKKKRKKRERGKERERKRKEREK 84
Query: 514 QAFEKWKEKKMEYLKEKNRKEREYERAKKQKEEETVAEKKKDNLTAVEKWNEKKEAFFKQ 573
Q E+ ++++ + KEK ++ER+ +++K+++ E++++N E+ +K+ ++
Sbjct: 85 QRKERREKERRKRKKEKKKRERKQRGRRERKKKKERKERERENKQRRERKRKKRRKKKRR 144
Query: 574 KEKEKINEKRKEELKRAEKKDKDKQAINEYEKWLENKEKQERIERKQKKR 623
KE+++ E+ K E KR ++K ++++ E + E K+++ER ER+++K+
Sbjct: 145 KERKREKERGKRERKRKKRKKEEREKKRERNR-KERKKERERKERRERKK 193
Score = 74.7 bits (182), Expect = 2e-13
Identities = 45/174 (25%), Positives = 95/174 (54%), Gaps = 9/174 (5%)
Query: 450 ESENLRIQNEQKKAAKREEALASFEAWKAMKEKEAKKIAAKKRLEEKNKKKTEEENAARK 509
ESE + + E++K + E E K KE KK ++R +E+ +K+ E E ++
Sbjct: 33 ESERKKERREREKRKREREKERKRERGK----KEKKKRKKRERGKERERKRKEREKQRKE 88
Query: 510 GEALQAFEKWKEKKMEYLKEKNRKEREYERAKKQKEEETVAEKKKDNLTAVEKWNEKKEA 569
+ ++ KEKK K++ R+ER+ ++ +K++E E +++ +K +KK
Sbjct: 89 RREKERRKRKKEKKKRERKQRGRRERKKKKERKERERENKQRRERKR----KKRRKKKRR 144
Query: 570 FFKQKEKEKINEKRKEELKRAEKKDKDKQAINEYEKWLENKEKQERIERKQKKR 623
+++EKE+ +RK + ++ E+++K ++ N E+ E + K+ R +K++K+
Sbjct: 145 KERKREKERGKRERKRKKRKKEEREKKRER-NRKERKKERERKERRERKKERKK 197
Score = 74.7 bits (182), Expect = 2e-13
Identities = 54/191 (28%), Positives = 102/191 (53%), Gaps = 17/191 (8%)
Query: 445 RIKRIESENLRIQNEQKKAAKREEALASFEAWKAMKEKEAKKIAAKKRLEEKNKKKTEEE 504
R + E + R + E+KK KRE + K KE +K ++R +E+ K+K E++
Sbjct: 48 REREKERKRERGKKEKKKRKKRERGKE-----RERKRKEREKQRKERREKERRKRKKEKK 102
Query: 505 NAARKGEALQAFEKWKEKKMEYLKEKNRKERE-YERAKKQKEEETVAEKKKDNLTAVEKW 563
RK + +K KE+K + K R+ER+ +R KK++ +E EK++ K
Sbjct: 103 KRERKQRGRRERKKKKERKERERENKQRRERKRKKRRKKKRRKERKREKERGKRERKRKK 162
Query: 564 NEKKEAFFKQKEKEKINEKRKEELKRAEKKDKDKQAINEYEKWLENKEKQERIERKQKKR 623
+K+E ++K++E+ ++RK+E +R E++++ K E+ E ++K+ER +K +K
Sbjct: 163 RKKEE---REKKRERNRKERKKERERKERRERKK------ERKKERRKKKER--KKDRKT 211
Query: 624 HSFLESEALPP 634
+S+ P
Sbjct: 212 DRQTDSQVFRP 222
Score = 70.1 bits (170), Expect = 6e-12
Identities = 44/151 (29%), Positives = 84/151 (55%), Gaps = 12/151 (7%)
Query: 480 KEKEAKKIAAKKRLEEKNKKKTEEENAARKGEALQAFEKWKEKKMEYLKEKNRKEREYER 539
+E E KK ++R EK K++ E+E +G+ EK K KK E KE+ RK +E E+
Sbjct: 32 RESERKK---ERREREKRKREREKERKRERGKK----EKKKRKKRERGKERERKRKEREK 84
Query: 540 AKKQKEEETVAEKKKDNLTAVEKWNEKKEAFFKQKEKEKINE-----KRKEELKRAEKKD 594
+K++ E+ ++KK+ K ++E K++ KE+ E +RK + +R +K+
Sbjct: 85 QRKERREKERRKRKKEKKKRERKQRGRRERKKKKERKERERENKQRRERKRKKRRKKKRR 144
Query: 595 KDKQAINEYEKWLENKEKQERIERKQKKRHS 625
K+++ E K ++K+++ ER++K+ +
Sbjct: 145 KERKREKERGKRERKRKKRKKEEREKKRERN 175
Score = 68.2 bits (165), Expect = 2e-11
Identities = 63/227 (27%), Positives = 112/227 (49%), Gaps = 19/227 (8%)
Query: 369 SSASARLMTSEFLKKSSSKRRTPSTTTSSHYLGTLKVLDQKPSQKQSIEPDRADNIRAAV 428
SS +A + +E S S P T S + +++ +K+ E ++
Sbjct: 6 SSRAAVKLNTELQMVSCSHISKPCTQRESE-----RKKERREREKRKREREKERKRERGK 60
Query: 429 YQEWLEKKNVYLHEMHRIKRIESENLRIQNEQKKAAKREEALASFEAWKAMKEKEAKKIA 488
++ KK E R KR E E R + +K+ KR+ K K++E K+
Sbjct: 61 KEKKKRKKRERGKERER-KRKEREKQRKERREKERRKRK---------KEKKKRERKQRG 110
Query: 489 AKKRLEEKNKKKTEEENAARKGEALQAFEKWKEKKMEYLKEKNRKEREYERAKKQKEEET 548
++R ++K +K+ E EN R+ E + + K+++ E +EK R +RE +R KK+K+EE
Sbjct: 111 RRERKKKKERKERERENKQRR-ERKRKKRRKKKRRKERKREKERGKRERKR-KKRKKEER 168
Query: 549 VAEKKKDNLTAVEKWNEKKEAFFKQKEKEKINEKRKEELKRAEKKDK 595
+K++ N +K E+KE ++KE++K K+KE K+ K D+
Sbjct: 169 -EKKRERNRKERKKERERKERRERKKERKKERRKKKER-KKDRKTDR 213
Score = 31.6 bits (70), Expect = 2.4
Identities = 21/84 (25%), Positives = 41/84 (48%), Gaps = 3/84 (3%)
Query: 550 AEKKKDNLTAVEKWNEKKEAFFKQKEKEK---INEKRKEELKRAEKKDKDKQAINEYEKW 606
A K L V + K ++ E++K EKRK E ++ K+++ K+ + +K
Sbjct: 10 AVKLNTELQMVSCSHISKPCTQRESERKKERREREKRKREREKERKRERGKKEKKKRKKR 69
Query: 607 LENKEKQERIERKQKKRHSFLESE 630
KE++ + + ++K+R E E
Sbjct: 70 ERGKERERKRKEREKQRKERREKE 93
>gi|148746195 trichohyalin [Homo sapiens]
Length = 1943
Score = 74.7 bits (182), Expect = 2e-13
Identities = 113/570 (19%), Positives = 224/570 (39%), Gaps = 70/570 (12%)
Query: 110 IKNEEEMAPDGCEDIVVKSFSESQNKDE--EFEKDKIKMKPKPRILSIKSTSSAENNSLD 167
+K EEE + E + + E + + E E E+++ + + K RI + +E ++
Sbjct: 659 LKREEE--EERLEQRLKREHEEERREQELAEEEQEQARERIKSRIPKWQWQLESEADARQ 716
Query: 168 TDDHFKPSPRPRSMLKKKSHMEEKDGLEDKETALSEELELHSAPSSLPTPNGIQLEAEKK 227
+ + +P R + +++ EEK + E EE H + + +
Sbjct: 717 SKVYSRP--RKQEGQRRRQEQEEKRRRRESELQWQEEERAHRQQQEEEQRRDFTWQWQAE 774
Query: 228 AFSENLDPEDSCLTSLASSSLKQILGDS-------FSPGSEGNASGKDPNEEITENHNSL 280
SE S L +Q+ + F P E + E + L
Sbjct: 775 EKSERGRQRLSARPPLREQRERQLRAEERQQREQRFLPEEEEKEQRRRQRREREKELQFL 834
Query: 281 KSDEN------------KENSFSADHVTTAVEKSKESQVTADDLEEEKAKAELIMDDDRT 328
+ +E +E+ D ++ + Q LEEE+ + +
Sbjct: 835 EEEEQLQRRERAQQLQEEEDGLQEDQERRRSQEQRRDQKWRWQLEEERKRRRHTLYAKPA 894
Query: 329 VDPLLSKSQSILISTSATASSKKTIEDRNIKNKKSTNNRASSASARLMTSE--FLKKSSS 386
+ L K Q +L ++ + K ++ R +L E L++
Sbjct: 895 LQEQLRKEQQLL-----QEEEEELQREEREKRRRQEQERQYREEEQLQQEEEQLLREERE 949
Query: 387 KRRTPSTTTSSHYLGTLKVLDQKPSQKQSIEPD-RADNIRAAVYQEWLEKKNVYLHEMHR 445
KRR K L QK Q EP+ R R Y+E E + E +
Sbjct: 950 KRRRQERERQYR---KDKKLQQKEEQLLGEEPEKRRRQEREKKYREEEELQQ----EEEQ 1002
Query: 446 IKRIESENLRIQNEQKKAAKREEALASFEAWKAMKEKEAKKIAAKKRLEEKNKKKTEEEN 505
+ R E E R Q +++ K++E L E +E+E K+RL+E+ ++ EEE
Sbjct: 1003 LLREEREKRRRQEWERQYRKKDE-LQQEEEQLLREERE------KRRLQERERQYREEEE 1055
Query: 506 AARKGEALQAFEKWKEKKME-----------------YLKEKNRKEREYERAKKQKEEET 548
++ E L E+ ++ E L+E+ K R ER ++ +EEE
Sbjct: 1056 LQQEEEQLLGEERETRRRQELERQYRKEEELQQEEEQLLREEPEKRRRQERERQCREEEE 1115
Query: 549 VAEKKKDNLTAVEKWNEKKEAFFKQKEKEKINEKRKEELKRAEKKDKDKQAINEY--EKW 606
+ ++++ L + ++E + +E+E++ ++ ++ L+ +K + ++ +Y E+
Sbjct: 1116 LQQEEEQLLREEREKRRRQELERQYREEEEVQQEEEQLLREEPEKRRRQELERQYREEEE 1175
Query: 607 LENKEKQ----ERIERKQKKRHSFLESEAL 632
L+ +E+Q E+ +R+Q++ + E E L
Sbjct: 1176 LQQEEEQLLREEQEKRRQERERQYREEEEL 1205
Score = 70.9 bits (172), Expect = 4e-12
Identities = 53/224 (23%), Positives = 122/224 (54%), Gaps = 22/224 (9%)
Query: 408 QKPSQKQSIEPDRADNIRAAVYQEWLEKKNVYLHEMHRIKRIESENLRIQNEQKKAAKRE 467
++ +KQ ++ D+ + R + WL+ L E R ++ E +++ EQ++ +RE
Sbjct: 468 EQERRKQQLKRDQEEERR----ERWLK-----LEEEERREQQERREQQLRREQEE--RRE 516
Query: 468 EALASFEAWKAMKEKEAKKIAAKKRLEEKNKK--KTEEENAARKGEALQAFEKWKEKKME 525
+ L E + ++++ + ++ EE+ ++ K EEE + Q ++ +E++ +
Sbjct: 517 QRLKRQEEEERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQERREQRLKREQEERRD 576
Query: 526 YLKEKNRKEREYERAKKQKEEETVAEKKKDNLTAVEKWNEKKEAFFKQKEKEKINEKRKE 585
L K +ER +R K+++EE K++ + +E+ E++E K++E E+ E+R++
Sbjct: 577 QLL-KREEERRQQRLKREQEERLEQRLKREEVERLEQ-EERREQRLKREEPEE--ERRQQ 632
Query: 586 ELKRAEKKDKDKQAI-----NEYEKWLENKEKQERIERKQKKRH 624
LK E++++ +Q + E+ L+ +E++ER+E++ K+ H
Sbjct: 633 LLKSEEQEERRQQQLRREQQERREQRLKREEEEERLEQRLKREH 676
Score = 70.5 bits (171), Expect = 5e-12
Identities = 63/346 (18%), Positives = 153/346 (44%), Gaps = 27/346 (7%)
Query: 281 KSDENKENSFSADHVTTAVEKSKESQVTADDLEEEKAKAELIMDDDRTVDPLLSKSQSIL 340
+ E + + + T E+ + Q D EEE+ + L ++++ + + Q +
Sbjct: 449 REQEERRDWLKREEETERHEQERRKQQLKRDQEEERRERWLKLEEEERREQQERREQQL- 507
Query: 341 ISTSATASSKKTIEDRNIKNKKSTNNRASSASARLMTSEFLKKSSSKRRTPSTTTSSHYL 400
++ E+R + K RL + + L++ +RR
Sbjct: 508 ---------RREQEERREQRLKRQEEE-ERLQQRLRSEQQLRREQEERREQLLKREEEKR 557
Query: 401 GTLKVLDQKPSQKQSIEPDRADNIRAAVYQEWLEKKNVYLHEMHRIKRIESENLRIQNEQ 460
+ +Q+ ++Q D+ Q+ L+++ E R+KR E E L + +
Sbjct: 558 LEQERREQRLKREQEERRDQLLKREEERRQQRLKREQEERLEQ-RLKREEVERLEQEERR 616
Query: 461 KKAAKREEALASFEAWKAMKEKEAKKIAAKKRLEEKNKKKTEEENAARKGEALQAFEKWK 520
++ KREE +E+ +++ + EE+ +++ E R+ + L+ +
Sbjct: 617 EQRLKREEP----------EEERRQQLLKSEEQEERRQQQLRREQQERREQRLK-----R 661
Query: 521 EKKMEYLKEKNRKEREYERAKKQKEEETVAEKKKDNLTAVEKWNEKKEAFFKQKEKEKIN 580
E++ E L+++ ++E E ER +++ EE + ++ + + KW + E+ ++ + +
Sbjct: 662 EEEEERLEQRLKREHEEERREQELAEEEQEQARERIKSRIPKWQWQLESEADARQSKVYS 721
Query: 581 EKRKEELKRAEKKDKDKQAINEYEKWLENKEKQERIERKQKKRHSF 626
RK+E +R ++ ++K+ E E + +E+ R ++++++R F
Sbjct: 722 RPRKQEGQRRRQEQEEKRRRRESELQWQEEERAHRQQQEEEQRRDF 767
Score = 68.2 bits (165), Expect = 2e-11
Identities = 39/185 (21%), Positives = 101/185 (54%), Gaps = 8/185 (4%)
Query: 442 EMHRIKRIESENLRIQNEQKKAAKREEALASFEAWKA---MKEKEAKKIAAKKRLEEKNK 498
++ R +++ E ++EQK +R E E + +K +E + ++R +++ K
Sbjct: 418 QLRREQQLRREQEEERHEQKHEQERREQRLKREQEERRDWLKREEETERHEQERRKQQLK 477
Query: 499 KKTEEENAARKGEALQAFEKWKEKKMEYLKEKNRKEREYERAKKQKEEETVAEKKKDNLT 558
+ EEE R + + + ++++ E + ++ER +R K+Q+EEE + ++ +
Sbjct: 478 RDQEEERRERWLKLEEEERREQQERREQQLRREQEERREQRLKRQEEEERLQQRLRSEQQ 537
Query: 559 AVEKWNEKKEAFFKQKEKEKINEKRKEELKRAEKKDKDKQAINEYEKWLENKEKQERIER 618
+ E++E K++E++++ ++R+E+ + E++++ Q + E + +Q+R++R
Sbjct: 538 LRREQEERREQLLKREEEKRLEQERREQRLKREQEERRDQLLKR-----EEERRQQRLKR 592
Query: 619 KQKKR 623
+Q++R
Sbjct: 593 EQEER 597
Score = 65.5 bits (158), Expect = 1e-10
Identities = 51/208 (24%), Positives = 105/208 (50%), Gaps = 19/208 (9%)
Query: 442 EMHRIKRIESENLRIQNE-----QKKAAKREEALASFEAWKAMKE--KEAKKIAAKKRLE 494
+ R KR E E + E Q++ +R+ E W+ +E + ++ A +++L+
Sbjct: 135 QRRRQKRQEQERELAEGEEQSEKQERLEQRDRQRRDEELWRQRQEWQEREERRAEEEQLQ 194
Query: 495 EKNKKKTEE---ENAARKGEALQAFEKWKEKKMEYLKEKNRKEREYERAKKQKEEETVAE 551
+TEE E R+ E L+ K +E+K + +E+ + + E K+ ++ ETV
Sbjct: 195 SCKGHETEEFPDEEQLRRRELLELRRKGREEKQQQRRERQDRVFQEEEEKEWRKRETVLR 254
Query: 552 KKKDNLTAVEKWNEKK----EAFFKQKEKEKINEKRKEELK-----RAEKKDKDKQAINE 602
K+++ L E +++ E ++ E++++ +R+EE + R E++ + KQ
Sbjct: 255 KEEEKLQEEEPQRQRELQEEEEQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEEER 314
Query: 603 YEKWLENKEKQERIERKQKKRHSFLESE 630
E+ E +E+QER E+++++R L E
Sbjct: 315 REQQEERREQQERREQQEERREQQLRRE 342
Score = 65.5 bits (158), Expect = 1e-10
Identities = 65/286 (22%), Positives = 137/286 (47%), Gaps = 30/286 (10%)
Query: 355 DRNIKNKKSTNNRASSASARLMTSEFLKKSSSKRRTPSTTTSSHYLGTLKVLDQKPSQKQ 414
+R + + +R S +L+ E + +RR + L+ +++P ++Q
Sbjct: 1300 EREEQKEAKRRDRKSQEEKQLLREE---REEKRRRQETDRKFREEEQLLQEREEQPLRRQ 1356
Query: 415 SIEPDRADNIRAAVYQEWLEKKNVYLHEMHRIKRIESENLRIQNEQK-KAAKREEALASF 473
E DR +QE K +L E R++R E E ++ EQ+ + +RE+ L
Sbjct: 1357 --ERDRKFREEELRHQEQGRK---FLEEEQRLRRQERERKFLKEEQQLRCQEREQQLRQD 1411
Query: 474 EAWKAMKEKEAKKIAAKKRLEEKNKKKTEEENAARKGEALQAFEKWKEKKMEYLKEKNRK 533
K +E++ + +E+++K EEE R+ E + K+ E++ + +E++RK
Sbjct: 1412 RDRKFREEEQ------QLSRQERDRKFREEEQQVRRQERER---KFLEEEQQLRQERHRK 1462
Query: 534 EREYERAKKQKEEETVAEKKKDNLTAVEKWNEKKEAFFKQKEKEKINEKRKEELKRAEKK 593
RE E+ +++EE+ + +++D K+ E+++ +Q+ K E+ + K
Sbjct: 1463 FREEEQLLQEREEQQLHRQERD-----RKFLEEEQQLRRQERDRKFREQELRSQEPERKF 1517
Query: 594 DKDKQAINEYE---KWLENKEKQERIERKQKKR----HSFLESEAL 632
+++Q ++ + K+L+ +++ R ER Q++R F E E L
Sbjct: 1518 LEEEQQLHRQQRQRKFLQEEQQLRRQERGQQRRQDRDRKFREEEQL 1563
Score = 65.1 bits (157), Expect = 2e-10
Identities = 46/237 (19%), Positives = 124/237 (52%), Gaps = 18/237 (7%)
Query: 412 QKQSIEPDRADNI-RAAVYQEWLEKKNVYLHEMHRIKRIESEN---LRIQNEQKKAAKRE 467
+KQ +R D + + +EW +++ V E +++ E + L+ + EQ + +R+
Sbjct: 225 EKQQQRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQRELQEEEEQLRKLERQ 284
Query: 468 EALASFEAWKAMKEKEAKKIAAKKRLEEKNKKKTEE--ENAARKGEALQAFEKWKEKKME 525
E + + +++ ++ +++ EE+ +++ EE E R+ + + E+ ++ E
Sbjct: 285 ELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQERREQQEERREQQLRREQE 344
Query: 526 YLKEKN-RKEREYERAKKQKEEETVAEKKKDNLTAVEKWNEKKEAFFKQKEKEKINEKRK 584
+E+ R+E+E ER ++Q E E+++ L ++ +++ +Q+ + + +R+
Sbjct: 345 ERREQQLRREQEEERREQQLRREQEEERREQQLRREQQLRREQQLRREQQLRREQQLRRE 404
Query: 585 EELKRAEKKDKDKQAINE-----------YEKWLENKEKQERIERKQKKRHSFLESE 630
++L+R ++ +++Q E +E+ E + +++R++R+Q++R +L+ E
Sbjct: 405 QQLRREQQLRREQQLRREQQLRREQEEERHEQKHEQERREQRLKREQEERRDWLKRE 461
Score = 64.7 bits (156), Expect = 3e-10
Identities = 46/207 (22%), Positives = 104/207 (50%), Gaps = 23/207 (11%)
Query: 446 IKRIESENLRIQNEQKKAAKREEALASFEAWKAMKEKEAKKIAAKK----------RLEE 495
+KR E Q +K+ KR++ E W ++E+E ++ ++ R E+
Sbjct: 458 LKREEETERHEQERRKQQLKRDQEEERRERWLKLEEEERREQQERREQQLRREQEERREQ 517
Query: 496 KNKKKTEEENAARKGEALQAFEKWKEKKMEYLKEKNRKEREYERAKKQKEEETVAEKKKD 555
+ K++ EEE ++ + Q + +E++ E L K +E+ E+ ++++ + E+++D
Sbjct: 518 RLKRQEEEERLQQRLRSEQQLRREQEERREQLL-KREEEKRLEQERREQRLKREQEERRD 576
Query: 556 NLTAVEK----------WNEKKEAFFKQKEKEKIN--EKRKEELKRAEKKDKDKQAINEY 603
L E+ E+ E K++E E++ E+R++ LKR E +++ +Q + +
Sbjct: 577 QLLKREEERRQQRLKREQEERLEQRLKREEVERLEQEERREQRLKREEPEEERRQQLLKS 636
Query: 604 EKWLENKEKQERIERKQKKRHSFLESE 630
E+ E +++Q R E+++++ E
Sbjct: 637 EEQEERRQQQLRREQQERREQRLKREE 663
Score = 64.3 bits (155), Expect = 3e-10
Identities = 65/324 (20%), Positives = 150/324 (46%), Gaps = 28/324 (8%)
Query: 312 LEEEKAKAELIMDDDRTVDPLLSKSQSILISTSATASSKKTIEDRNIKNKKSTNNRASSA 371
LE+E+ + L + + D LL + + K+ E+R R
Sbjct: 558 LEQERREQRLKREQEERRDQLLKREEE-----RRQQRLKREQEER-------LEQRLKRE 605
Query: 372 SARLMTSEFLKKSSSKRRTPSTTTSSHYLGTLKVLDQKPSQKQSIEPDRADN-IRAAVYQ 430
+ E ++ KR P L + + +++ Q + + +R + ++ +
Sbjct: 606 EVERLEQEERREQRLKREEPEEERRQQLLKSEEQEERRQQQLRREQQERREQRLKREEEE 665
Query: 431 EWLEKKNVYLHEMHRIKRIESENLRIQNEQKKAAKREEALASFEAWKAMKEKEAK--KIA 488
E LE++ L H +R E E + EQ++A +R ++ W+ E +A+ K+
Sbjct: 666 ERLEQR---LKREHEEERREQE--LAEEEQEQARERIKSRIPKWQWQLESEADARQSKVY 720
Query: 489 AKKRLEEKNKKKTEEENAARKGEALQAFEKWKEKKMEYLKEKNRKEREYERAKKQKEEET 548
++ R +E +++ E+E R+ E+ +W+E++ + +++ ++R + Q EE+
Sbjct: 721 SRPRKQEGQRRRQEQEEKRRRRESEL---QWQEEERAHRQQQEEEQRRDFTWQWQAEEK- 776
Query: 549 VAEKKKDNLTAVEKWNEKKEAFFKQKEKEKINEKRKEELKRAEKKDKDKQAINEYEKWLE 608
+E+ + L+A E++E +Q E+ ++ + L E+K++ ++ E EK L+
Sbjct: 777 -SERGRQRLSARPPLREQRE---RQLRAEERQQREQRFLPEEEEKEQRRRQRREREKELQ 832
Query: 609 NKEKQERIERKQKKRHSFLESEAL 632
E++E+++R+++ + E + L
Sbjct: 833 FLEEEEQLQRRERAQQLQEEEDGL 856
Score = 64.3 bits (155), Expect = 3e-10
Identities = 53/238 (22%), Positives = 120/238 (50%), Gaps = 14/238 (5%)
Query: 408 QKPSQKQSIEPDRADNIRAAVYQEWLEKKNVYLHEMHRIKRIESENLRIQNEQKKAAKRE 467
Q+ Q++ + DR + QE E++ + E R R+E + +R Q +++K + E
Sbjct: 1543 QERGQQRRQDRDRKFREEEQLRQE-REEQQLSRQERDRKFRLEEQKVRRQEQERKFMEDE 1601
Query: 468 EALASFEAWKAMKEKEAKKIAAKKRL-EEKNKKKTEEENAARKGEALQAFEKWKEKKMEY 526
+ L E + ++++ +K ++L +E+ +++ + RK + + +E++ +
Sbjct: 1602 QQLRRQEGQQQLRQERDRKFREDEQLLQEREEQQLHRQERDRKFLEEEPQLRRQEREQQL 1661
Query: 527 LKEKNRKEREYERAKKQKEEETVAEKKKDNLTAVEKW---NEKKEAFFKQKEKEKINEK- 582
+++RK RE E+ ++ EE+ + +++D E+ +++E F Q+E++ ++
Sbjct: 1662 RHDRDRKFREEEQLLQEGEEQQLRRQERDRKFREEEQQLRRQERERKFLQEEQQLRRQEL 1721
Query: 583 ----RKEELKRAEKKDKDKQAINEYEKWLENK----EKQERIERKQKKRHSFLESEAL 632
R+EE R E + + + Y K LE + E++E+ R+Q++ F E E L
Sbjct: 1722 ERKFREEEQLRQETEQEQLRRQERYRKILEEEQLRPEREEQQLRRQERDRKFREEEQL 1779
Score = 63.9 bits (154), Expect = 4e-10
Identities = 59/248 (23%), Positives = 121/248 (48%), Gaps = 34/248 (13%)
Query: 404 KVLDQKPS-----QKQSIEPDRADNIRAA--VYQEWLEKKNVYLHEMHRIKRIESENLRI 456
K L+++P ++Q + DR R + QE E++ + E R R E + LR
Sbjct: 1644 KFLEEEPQLRRQEREQQLRHDRDRKFREEEQLLQEG-EEQQLRRQERDRKFREEEQQLRR 1702
Query: 457 QNEQKKAAKREEALASFEAWKAMKEKEA-----------KKIAAKKRLEEKNKKKTEEEN 505
Q ++K + E+ L E + +E+E ++ +K LEE+ + EE
Sbjct: 1703 QERERKFLQEEQQLRRQELERKFREEEQLRQETEQEQLRRQERYRKILEEEQLRPEREEQ 1762
Query: 506 AARKGEALQAFEKWKEKKMEY------LKEKNRKEREYERAKKQKEEETVAEKKKDNLTA 559
R+ E + F + ++ + E +E +RK RE E+ ++++EE+ + +++D
Sbjct: 1763 QLRRQERDRKFREEEQLRQEREEQQLRSQESDRKFREEEQLRQEREEQQLRPQQRDG--- 1819
Query: 560 VEKWNEKKEAFFKQKEKEKINEKRKEELKRAEK-KDKDKQAINEYEKWLENKEK--QERI 616
K+ ++E +++++++ ++R + + E+ ++K E E W E ++K QER
Sbjct: 1820 --KYRWEEEQLQLEEQEQRLRQERDRQYRAEEQFATQEKSRREEQELWQEEEQKRRQER- 1876
Query: 617 ERKQKKRH 624
ERK ++ H
Sbjct: 1877 ERKLREEH 1884
Score = 62.8 bits (151), Expect = 1e-09
Identities = 42/196 (21%), Positives = 104/196 (53%), Gaps = 8/196 (4%)
Query: 430 QEWLEKKNVYLHEMHRIKRIESENLRIQNEQKKAAKREEALASFEAWKAMKEKEAKKIAA 489
+E LE + E + +R + + + E+K+ KRE L E K +E+ ++
Sbjct: 213 RELLELRRKGREEKQQQRRERQDRVFQEEEEKEWRKRETVLRKEEE-KLQEEEPQRQREL 271
Query: 490 KKRLEEKNKKKTEEENAARKGEALQAFEKWKEKKMEYLKEKNRKEREYERAKKQKEEETV 549
++ E+ K + +E R+ E Q +E+++ +E+ R+E++ ER ++Q+ E
Sbjct: 272 QEEEEQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQERREQQ 331
Query: 550 AEKKKDNLTAVEKWNEKKEAFFKQKEKEKINEKRKEELKRAEKKDKDKQAINEYEKWLEN 609
E+++ L E++E +Q +E+ E+R+++L+R +++++ +Q + ++
Sbjct: 332 EERREQQLR-----REQEERREQQLRREQEEERREQQLRREQEEERREQQLRREQQLRRE 386
Query: 610 KE--KQERIERKQKKR 623
++ +++++ R+Q+ R
Sbjct: 387 QQLRREQQLRREQQLR 402
Score = 61.6 bits (148), Expect = 2e-09
Identities = 44/214 (20%), Positives = 109/214 (50%), Gaps = 26/214 (12%)
Query: 434 EKKNVYLHEMHRIKRIESENLRIQNEQKKAAKREEALASFEAWKAMKEKEAKKIAAKKRL 493
E++ L +++R + Q +++ +RE+ L + + ++ ++ +++
Sbjct: 371 ERREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQE 430
Query: 494 EEKNKKKTEEENAARKGEALQAFEKWKEKKMEYLKEKNRKER-EYERAKKQKEEETVAEK 552
EE++++K E+E Q ++ +E++ ++LK + ER E ER K+Q + + E+
Sbjct: 431 EERHEQKHEQERRE------QRLKREQEERRDWLKREEETERHEQERRKQQLKRDQEEER 484
Query: 553 KKDNLTAVEKWNEKKEAFFKQKEKEKINEKRKEELKRAEKKDKDKQAI------------ 600
++ L E+ +++ +Q+ + + E+R++ LKR E++++ +Q +
Sbjct: 485 RERWLKLEEEERREQQERREQQLRREQEERREQRLKRQEEEERLQQRLRSEQQLRREQEE 544
Query: 601 -------NEYEKWLENKEKQERIERKQKKRHSFL 627
E EK LE + +++R++R+Q++R L
Sbjct: 545 RREQLLKREEEKRLEQERREQRLKREQEERRDQL 578
Score = 60.1 bits (144), Expect = 6e-09
Identities = 53/274 (19%), Positives = 128/274 (46%), Gaps = 29/274 (10%)
Query: 381 LKKSSSKRRTPSTTTSSHYLGTLKVLDQKPSQKQSIEPDRADNIRAAVYQEWLEKKNVYL 440
L++ +RR L + +K + + + R D QEW E++
Sbjct: 129 LEEEPGQRRRQKRQEQERELAEGEEQSEKQERLEQRDRQRRDEELWRQRQEWQEREERRA 188
Query: 441 HEMH----------------RIKRIESENLRIQNEQKKAAKREEALASFEAWKAMKEKEA 484
E +++R E LR + ++K +R E + +E+E
Sbjct: 189 EEEQLQSCKGHETEEFPDEEQLRRRELLELRRKGREEKQQQRRERQD-----RVFQEEEE 243
Query: 485 KKIAAKKRLEEKNKKKTEEENAARKGEALQAFEKWKE-KKMEYLKEKNRKEREYERAKKQ 543
K+ ++ + K ++K +EE R+ E + E+ ++ ++ E +E+ +E++ +R +++
Sbjct: 244 KEWRKRETVLRKEEEKLQEEEPQRQRELQEEEEQLRKLERQELRRERQEEEQQQQRLRRE 303
Query: 544 -----KEEETVAEKKKDNLTAVEKWNEKKEAFFKQKEKEKINEKRKEELKRAEKKDKDKQ 598
K+EE E++++ E+ +++E +Q +E+ E+R+++L+R +++++ +Q
Sbjct: 304 QQLRRKQEEERREQQEERREQQERREQQEERREQQLRREQ-EERREQQLRREQEEERREQ 362
Query: 599 AINEYEKWLENKEKQERIERKQKKRHSFLESEAL 632
+ E+ E +E+Q R E++ ++ + L
Sbjct: 363 QLRR-EQEEERREQQLRREQQLRREQQLRREQQL 395
Score = 60.1 bits (144), Expect = 6e-09
Identities = 41/199 (20%), Positives = 108/199 (54%), Gaps = 15/199 (7%)
Query: 434 EKKNVYLHEMHRIKRIESENLRIQNEQKKAAKREEALASFEAWKAMKEKEAKKIAAKKRL 493
+++ +L E +++R E R Q+ +K + E+ E + +++ +K RL
Sbjct: 1528 QRQRKFLQEEQQLRRQERGQQRRQDRDRKFREEEQLRQEREEQQLSRQERDRKF----RL 1583
Query: 494 EEKNKKKTEEENAARKGEALQAFEKWKEKKMEYLKEKNRKEREYERAKKQKEEETVAEKK 553
EE+ ++ E+E + E Q + +E + + +E++RK RE E+ +++EE+ + ++
Sbjct: 1584 EEQKVRRQEQERKFMEDE--QQLRR-QEGQQQLRQERDRKFREDEQLLQEREEQQLHRQE 1640
Query: 554 KDNLTAVEKWNEKKEAFFKQKEKEKINEKRKEELKRAEK--KDKDKQAINEYEKWLENKE 611
+D K+ E++ +Q+ ++++ R + + E+ ++ ++Q + E+ + +E
Sbjct: 1641 RD-----RKFLEEEPQLRRQEREQQLRHDRDRKFREEEQLLQEGEEQQLRRQERDRKFRE 1695
Query: 612 KQERIERKQKKRHSFLESE 630
+++++ R++++R FL+ E
Sbjct: 1696 EEQQLRRQERER-KFLQEE 1713
Score = 58.2 bits (139), Expect = 2e-08
Identities = 45/241 (18%), Positives = 121/241 (50%), Gaps = 21/241 (8%)
Query: 404 KVLDQKPSQKQSIEPDRADNIRAAVYQEWLEKKNVYLHEMHRIKRIESENLRIQNEQKKA 463
K+ +++P +++ ++ + + +R QE ++ + R++R + LR + E+++
Sbjct: 259 KLQEEEPQRQRELQEEE-EQLRKLERQELRRERQEEEQQQQRLRR--EQQLRRKQEEERR 315
Query: 464 AKREEALASFEAWKAMKEKEAKKIAAKKRLEEKNKKKTEEENAARKGEALQAFEKWKEKK 523
++EE E + +E+ +++ ++ EE+ +++ E + E E+ +E++
Sbjct: 316 EQQEERREQQERREQQEERREQQL--RREQEERREQQLRREQEEERREQQLRREQEEERR 373
Query: 524 MEYLKEKNRKEREYERAKKQKEEETVAEKKKDNLTAVEKWNEKKEAFFKQ---KEKEKIN 580
+ L+ + + RE + ++Q+ +++ L ++ +++ +Q +E+E+
Sbjct: 374 EQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQEEER 433
Query: 581 EKRKEELKRAEKKDKDKQAINEYEKWLENKEKQERIERKQKK-----------RHSFLES 629
++K E +R E++ K +Q E WL+ +E+ ER E++++K R +L+
Sbjct: 434 HEQKHEQERREQRLKREQ--EERRDWLKREEETERHEQERRKQQLKRDQEEERRERWLKL 491
Query: 630 E 630
E
Sbjct: 492 E 492
Score = 56.6 bits (135), Expect = 7e-08
Identities = 41/200 (20%), Positives = 102/200 (51%), Gaps = 15/200 (7%)
Query: 434 EKKNVYLHEMHRIKRIESENLRIQNEQKKAAKREEALASFEAWKAMKEKEAKKIAAKK-- 491
E+ +L E +++R E E + +K + E+ L E + +++ +K ++
Sbjct: 1640 ERDRKFLEEEPQLRRQEREQQLRHDRDRKFREEEQLLQEGEEQQLRRQERDRKFREEEQQ 1699
Query: 492 -RLEEKNKKKTEEENAARKGEALQAFEKWKEKKMEYLKEKNRKEREYERAKKQKEEETVA 550
R +E+ +K +EE R+ E + F + ++ + E +E+ R++ Y K +EE+
Sbjct: 1700 LRRQERERKFLQEEQQLRRQELERKFREEEQLRQETEQEQLRRQERYR--KILEEEQLRP 1757
Query: 551 EKKKDNLTAVEKWNEKKEAFFKQKEKEKINEKRKEELKRAEKKDKDKQAINEYEKWLENK 610
E+++ L ++E K +E+E++ ++R+E+ R+++ D+ E E+ + +
Sbjct: 1758 EREEQQL-------RRQERDRKFREEEQLRQEREEQQLRSQESDRK---FREEEQLRQER 1807
Query: 611 EKQERIERKQKKRHSFLESE 630
E+Q+ +++ ++ + E +
Sbjct: 1808 EEQQLRPQQRDGKYRWEEEQ 1827
Score = 55.5 bits (132), Expect = 2e-07
Identities = 41/230 (17%), Positives = 119/230 (51%), Gaps = 12/230 (5%)
Query: 407 DQKPSQKQSIEPDRADNIRAAVYQEWLEKKNVYLHEMHRIKRIESENLRIQNEQKKAAKR 466
+++ ++Q R +R +E E++ + R R + E R Q +++ +R
Sbjct: 289 ERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQER--REQQEERREQQLRREQEER 346
Query: 467 EEALASFEAWKAMKEKEAKKIAAKKRLEEKNKKKTEEENAARKGEALQAFEKWKEKKMEY 526
E E + +E++ ++ ++ EE+ +++ E R+ + L+ ++ + ++
Sbjct: 347 REQQLRREQEEERREQQLRR----EQEEERREQQLRREQQLRREQQLRREQQLRREQQLR 402
Query: 527 LKEKNRKEREYERAKKQKEEETVAEKKKDNLTAVEKWNEKKEAFFKQKEKEKIN-EKRKE 585
+++ R+E++ R ++ + E+ + ++++ + E++E K++++E+ + KR+E
Sbjct: 403 REQQLRREQQLRREQQLRREQQLRREQEEERHEQKHEQERREQRLKREQEERRDWLKREE 462
Query: 586 ELKRAEKKDKDKQAINEY-----EKWLENKEKQERIERKQKKRHSFLESE 630
E +R E++ + +Q + E+WL+ +E++ R +++++++ E E
Sbjct: 463 ETERHEQERRKQQLKRDQEEERRERWLKLEEEERREQQERREQQLRREQE 512
Score = 55.5 bits (132), Expect = 2e-07
Identities = 44/200 (22%), Positives = 101/200 (50%), Gaps = 27/200 (13%)
Query: 434 EKKNVYLHEMHRIKRIESENLRIQNEQKKAAKREEALASF-EAWKAMKEKEAKKIAAKKR 492
E++ LH R ++ E +++ ++++ R + F E + ++E E +++ R
Sbjct: 1630 EREEQQLHRQERDRKFLEEEPQLRRQEREQQLRHDRDRKFREEEQLLQEGEEQQL----R 1685
Query: 493 LEEKNKKKTEEENAARKGEALQAFEKWKEKKMEYLKEKNRKEREYERAKKQKEEETVAEK 552
+E+++K EEE R+ +E++ ++L+E+ + R+ K ++EE+ E
Sbjct: 1686 RQERDRKFREEEQQLRR----------QERERKFLQEEQQLRRQELERKFREEEQLRQET 1735
Query: 553 KKDNLTAVEKWNEKKEAFFKQKEKEKINEKRKEELKRAEKKDKDKQAINEYEKWLENKEK 612
+++ L ++E + K E+E++ +R+E+ R +++D+ E E+ + +E+
Sbjct: 1736 EQEQL-------RRQERYRKILEEEQLRPEREEQQLRRQERDR---KFREEEQLRQEREE 1785
Query: 613 QERIERKQKKRHSFLESEAL 632
Q+ R Q+ F E E L
Sbjct: 1786 QQL--RSQESDRKFREEEQL 1803
Score = 54.7 bits (130), Expect = 3e-07
Identities = 36/190 (18%), Positives = 101/190 (53%), Gaps = 3/190 (1%)
Query: 442 EMHRIKRIESENLRIQNEQKKAAKREEALASFEAWKAMKEKEAKKIAAKKRLEEKNKKKT 501
++ R +++ E +++ EQ+ ++EE + + +E+ K+ ++R K +++T
Sbjct: 406 QLRREQQLRREQ-QLRREQQLRREQEEERHEQKHEQERREQRLKREQEERRDWLKREEET 464
Query: 502 EEENAARKGEALQAFEKWKEKKMEYLKEKNRKEREYERAKKQKEEETVAEKKKDNLTAVE 561
E R+ + L+ ++ +E++ +LK + + RE + ++Q+ E+++ L E
Sbjct: 465 ERHEQERRKQQLKRDQE-EERRERWLKLEEEERREQQERREQQLRREQEERREQRLKRQE 523
Query: 562 KWNEKKEAFFKQKEKEKINEKRKEE-LKRAEKKDKDKQAINEYEKWLENKEKQERIERKQ 620
+ ++ +++ + E+R+E+ LKR E+K +++ + K + + + + ++R++
Sbjct: 524 EEERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQERREQRLKREQEERRDQLLKREE 583
Query: 621 KKRHSFLESE 630
++R L+ E
Sbjct: 584 ERRQQRLKRE 593
Score = 53.9 bits (128), Expect = 4e-07
Identities = 48/203 (23%), Positives = 97/203 (47%), Gaps = 29/203 (14%)
Query: 434 EKKNVYLHEMHRIKRIESENLRIQNEQKKAAKREEALASFEAWKAMKEKEAKKIAAKK-- 491
E++ +L E +++R E E + EQ + +E L E ++ + E+E + ++
Sbjct: 1704 ERERKFLQEEQQLRRQELERKFREEEQLRQETEQEQLRRQERYRKILEEEQLRPEREEQQ 1763
Query: 492 -RLEEKNKKKTEEENAARKGEALQAFEKWKEKKMEYLKEKNRKEREYERAKKQK------ 544
R +E+++K EEE ++ E Q + ++K +E+ R+ERE ++ + Q+
Sbjct: 1764 LRRQERDRKFREEEQLRQEREEQQLRSQESDRKFRE-EEQLRQEREEQQLRPQQRDGKYR 1822
Query: 545 --EEETVAEKKKDNLTAVEKWNEKKEAFFKQKEKEKINEK---RKEELKRAEKKDKDKQA 599
EE+ E+++ L + E F +EK + E+ ++EE KR +++
Sbjct: 1823 WEEEQLQLEEQEQRLRQERDRQYRAEEQFATQEKSRREEQELWQEEEQKRRQER------ 1876
Query: 600 INEYEKWLENKEKQERIERKQKK 622
E K ++E I R+QK+
Sbjct: 1877 --------ERKLREEHIRRQQKE 1891
Score = 53.5 bits (127), Expect = 6e-07
Identities = 40/216 (18%), Positives = 111/216 (51%), Gaps = 2/216 (0%)
Query: 408 QKPSQKQSIEPDRADNIRAAVYQEWLEKKNVYLHEMHRIKRIESENLRIQNEQKKAAKRE 467
Q+ +++ E R R +E E++ E R +++ E + EQ+ ++E
Sbjct: 310 QEEERREQQEERREQQERREQQEERREQQLRREQEERREQQLRREQEEERREQQLRREQE 369
Query: 468 EALASFEAWKAMKEKEAKKIAAKKRLEEKNKKKTEEENAARKGEALQAFEKWKEKKMEYL 527
E + + + + +++ +++L + + + E++ R+ + + + +E+++
Sbjct: 370 EERREQQLRREQQLRREQQLRREQQLRREQQLRREQQ-LRREQQLRREQQLRREQQLRRE 428
Query: 528 KEKNRKEREYERAKKQKEEETVAEKKKDNLTAVEKWNEKKEAFFKQKEKEKINEKRKEE- 586
+E+ R E+++E+ ++++ + E+++D L E+ ++ KQ+ K E+R+E
Sbjct: 429 QEEERHEQKHEQERREQRLKREQEERRDWLKREEETERHEQERRKQQLKRDQEEERRERW 488
Query: 587 LKRAEKKDKDKQAINEYEKWLENKEKQERIERKQKK 622
LK E++ +++Q E + E +E++E+ ++Q++
Sbjct: 489 LKLEEEERREQQERREQQLRREQEERREQRLKRQEE 524
Score = 53.5 bits (127), Expect = 6e-07
Identities = 44/197 (22%), Positives = 97/197 (49%), Gaps = 18/197 (9%)
Query: 452 ENLRIQNEQKKAAKREEALASFEAWKAMKEKEAKK---IAAKKRLEEKNKKKTEEENAAR 508
E +++ E++K AKR + + E +E+E K+ +K EE+ + EE R
Sbjct: 1295 EEEQLEREEQKEAKRRDRKSQEEKQLLREEREEKRRRQETDRKFREEEQLLQEREEQPLR 1354
Query: 509 KGEALQAFE----KWKEKKMEYLKEKNRKEREYERAKKQKEEETVAEKKKDNLTAVE--- 561
+ E + F + +E+ ++L+E+ R R+ K KEE+ + ++++ +
Sbjct: 1355 RQERDRKFREEELRHQEQGRKFLEEEQRLRRQERERKFLKEEQQLRCQEREQQLRQDRDR 1414
Query: 562 KWNEKKEAFFKQKEKEKINEK----RKEELKRAEKKDKDKQAINEYEKWLEN----KEKQ 613
K+ E+++ +Q+ K E+ R++E +R +++ + + K+ E +E++
Sbjct: 1415 KFREEEQQLSRQERDRKFREEEQQVRRQERERKFLEEEQQLRQERHRKFREEEQLLQERE 1474
Query: 614 ERIERKQKKRHSFLESE 630
E+ +Q++ FLE E
Sbjct: 1475 EQQLHRQERDRKFLEEE 1491
Score = 53.1 bits (126), Expect = 8e-07
Identities = 47/225 (20%), Positives = 113/225 (50%), Gaps = 31/225 (13%)
Query: 430 QEWLEKKNVYLHEMHRIKRIESENLRIQNEQK-KAAKREEALASFEAWKAMKEKEAKKIA 488
+++LE++ E HR R E + L+ + EQ+ +R+ E +E++ K
Sbjct: 1446 RKFLEEEQQLRQERHRKFREEEQLLQEREEQQLHRQERDRKFLEEEQQLRRQERDRKFRE 1505
Query: 489 AKKRLEEKNKKKTEEENAARKGEALQAFE------KWKEKKMEYLKEKNRKEREYERAKK 542
+ R +E +K EEE + + + F + +E+ + ++++RK RE E+ ++
Sbjct: 1506 QELRSQEPERKFLEEEQQLHRQQRQRKFLQEEQQLRRQERGQQRRQDRDRKFREEEQLRQ 1565
Query: 543 QKEEETVAEKKKDNLTAVE-----------KWNEKKEAFFKQKEKEKINEKRKEELKRAE 591
++EE+ ++ +++D +E K+ E ++ +Q+ ++++ ++R + + E
Sbjct: 1566 EREEQQLSRQERDRKFRLEEQKVRRQEQERKFMEDEQQLRRQEGQQQLRQERDRKFREDE 1625
Query: 592 K--KDKDKQAINEYE---KWLEN--------KEKQERIERKQKKR 623
+ +++++Q ++ E K+LE +E+Q R +R +K R
Sbjct: 1626 QLLQEREEQQLHRQERDRKFLEEEPQLRRQEREQQLRHDRDRKFR 1670
Score = 52.8 bits (125), Expect = 1e-06
Identities = 61/270 (22%), Positives = 122/270 (45%), Gaps = 60/270 (22%)
Query: 412 QKQSIEPDRADNIRAAVYQEWLEKKNVYLHEMHRI-----KRIESENLRIQNEQKKAAKR 466
++Q + +R R + +++ E++ V E + KR E R E+++ +
Sbjct: 1120 EEQLLREEREKRRRQELERQYREEEEVQQEEEQLLREEPEKRRRQELERQYREEEELQQE 1179
Query: 467 EEALASFEAWKAMKEKEAKKIAAKKRLEEKNKKK---------------TEEENAAR--- 508
EE L E K +E+E + ++ +K K++ E+ENA R
Sbjct: 1180 EEQLLREEQEKRRQERERQYREEEELQRQKRKQRYRDEDQRSDLKWQWEPEKENAVRDNK 1239
Query: 509 ---KGEALQAFEKWKEKKME----------YLKEKNRKEREYERAKKQK-------EEET 548
KG + F + ++ ++ L E+ ++RE ER + Q+ EE+
Sbjct: 1240 VYCKGRENEQFRQLEDSQLRDRQSQQDLQHLLGEQQERDREQERRRWQQRDRHFPEEEQL 1299
Query: 549 VAEKKKDNLTAVEKWNEKKEAFFKQKEKEKINEKRKEELKRAE---KKDKDKQAINEYEK 605
E++K+ K ++K Q+EK+ + E+R+E+ +R E K +++Q + E E+
Sbjct: 1300 EREEQKE-----AKRRDRK----SQEEKQLLREEREEKRRRQETDRKFREEEQLLQEREE 1350
Query: 606 WLENKEKQERIERKQKKRH-----SFLESE 630
+++++R R+++ RH FLE E
Sbjct: 1351 QPLRRQERDRKFREEELRHQEQGRKFLEEE 1380
Score = 52.8 bits (125), Expect = 1e-06
Identities = 52/243 (21%), Positives = 119/243 (48%), Gaps = 27/243 (11%)
Query: 407 DQKPSQKQSIEPDRADNIRA-AVYQEWLEKKNVYLHEMHRIKRIESEN-----LRIQNEQ 460
DQ+ K EP++ + +R VY + E + E +++ +S+ L Q E+
Sbjct: 1218 DQRSDLKWQWEPEKENAVRDNKVYCKGRENEQFRQLEDSQLRDRQSQQDLQHLLGEQQER 1277
Query: 461 KKAAKR-----------EEALASFEAWKAMKEKEAKKIAAKKRLEEKNKKKTEEENAARK 509
+ +R EE E K K ++ K K+ L E+ ++K + RK
Sbjct: 1278 DREQERRRWQQRDRHFPEEEQLEREEQKEAKRRDRKSQEEKQLLREEREEKRRRQETDRK 1337
Query: 510 GEALQAFEKWKEKKMEYLKEKNRKEREYERAKKQKEEETVAEKKKDNLTAVEKWNEKKEA 569
+ + +E++ +E++RK RE E +++ + + E+++ + E++
Sbjct: 1338 FREEEQLLQEREEQPLRRQERDRKFREEELRHQEQGRKFLEEEQR------LRRQERERK 1391
Query: 570 FFKQKEKEKINEKRKEELK--RAEKKDKDKQAINEYEKWLENKEKQERIERKQKKRHSFL 627
F K++++ + E R+++L+ R K +++Q ++ E+ + +E+++++ R++++R FL
Sbjct: 1392 FLKEEQQLRCQE-REQQLRQDRDRKFREEEQQLSRQERDRKFREEEQQVRRQERER-KFL 1449
Query: 628 ESE 630
E E
Sbjct: 1450 EEE 1452
Score = 52.4 bits (124), Expect = 1e-06
Identities = 38/170 (22%), Positives = 91/170 (53%), Gaps = 7/170 (4%)
Query: 446 IKRIESENLRIQNEQKKAAKREEALASFEAWKAMKEKEAKKIAAKKRLEEKNKKKTEEEN 505
+++ E + LR + E+++ +RE E + +E+ ++ K+R +E ++ EEE
Sbjct: 1086 LQQEEEQLLREEPEKRRRQERERQCREEEELQQEEEQLLREEREKRRRQELERQYREEEE 1145
Query: 506 AARKGEALQAFEKWKEKKMEYLKEKNRKEREYERAKKQKEEETVAEKKKDNLTAVEKWNE 565
++ E L E K ++ E L+ + R+E E + Q+EE+ + E+++ E+
Sbjct: 1146 VQQEEEQLLREEPEKRRRQE-LERQYREEEELQ----QEEEQLLREEQEKRRQERERQYR 1200
Query: 566 KKEAFFKQKEKEKI-NEKRKEELKRAEKKDKDKQAINEYEKWLENKEKQE 614
++E +QK K++ +E ++ +LK + +K+ A+ + + + + +E ++
Sbjct: 1201 EEEELQRQKRKQRYRDEDQRSDLKWQWEPEKE-NAVRDNKVYCKGRENEQ 1249
Score = 51.6 bits (122), Expect = 2e-06
Identities = 52/253 (20%), Positives = 120/253 (47%), Gaps = 29/253 (11%)
Query: 404 KVLDQKPSQKQSIEPDRADNIRAAVYQE----WLEKKNVYLHEMHRIKRIESENLRIQNE 459
++L ++P +++ E +R + QE E++ E R R E E +Q +
Sbjct: 1152 QLLREEPEKRRRQELERQYREEEELQQEEEQLLREEQEKRRQERERQYREEEE---LQRQ 1208
Query: 460 QKKAAKREEALASFEAWKAMKEKEA----KKIAAKKRLEEKNKKKTEEENAARKGEA--- 512
++K R+E S W+ EKE K+ K R E+ ++ + + R+ +
Sbjct: 1209 KRKQRYRDEDQRSDLKWQWEPEKENAVRDNKVYCKGRENEQFRQLEDSQLRDRQSQQDLQ 1268
Query: 513 -----------LQAFEKWKEKKMEYLKEKNRKEREYERAKKQKEEETVAEKKKDNLTAVE 561
Q +W+++ + E+ + ERE ++ K+++ ++ EK+ E
Sbjct: 1269 HLLGEQQERDREQERRRWQQRDRHF-PEEEQLEREEQKEAKRRDRKSQEEKQLLREEREE 1327
Query: 562 KWNEKKEAFFKQKEKEKINEKRKEELKRAEKKDKD--KQAINEYEKWLENKEKQERIERK 619
K ++E K +E+E++ ++R+E+ R +++D+ ++ + E+ + E+++R+ R+
Sbjct: 1328 K-RRRQETDRKFREEEQLLQEREEQPLRRQERDRKFREEELRHQEQGRKFLEEEQRLRRQ 1386
Query: 620 QKKRHSFLESEAL 632
+++R E + L
Sbjct: 1387 ERERKFLKEEQQL 1399
Score = 50.8 bits (120), Expect = 4e-06
Identities = 39/187 (20%), Positives = 91/187 (48%), Gaps = 23/187 (12%)
Query: 422 DNIRAAVYQEWLEKKNVYLHEMHRIKRIESENLRIQNEQKKAAKREEALASFEAWKAMKE 481
+ +R QE L ++ Y K +E E LR + E+++ ++E E + +E
Sbjct: 1729 EQLRQETEQEQLRRQERYR------KILEEEQLRPEREEQQLRRQERDRKFREEEQLRQE 1782
Query: 482 KEAKKIAAK---KRLEEKNKKKTEEENAARKGEALQAFEKWKEKKMEYLKEKNRKEREYE 538
+E +++ ++ ++ E+ + + E E + + +W+E++++ L+E+ ++ R+ E
Sbjct: 1783 REEQQLRSQESDRKFREEEQLRQEREEQQLRPQQRDGKYRWEEEQLQ-LEEQEQRLRQ-E 1840
Query: 539 RAKKQKEEETVAEKKKDNLTAVEKWNEK------------KEAFFKQKEKEKINEKRKEE 586
R ++ + EE A ++K E W E+ +E ++++KE+ ++ E
Sbjct: 1841 RDRQYRAEEQFATQEKSRREEQELWQEEEQKRRQERERKLREEHIRRQQKEEQRHRQVGE 1900
Query: 587 LKRAEKK 593
+K E K
Sbjct: 1901 IKSQEGK 1907
Score = 50.4 bits (119), Expect = 5e-06
Identities = 81/378 (21%), Positives = 172/378 (45%), Gaps = 44/378 (11%)
Query: 267 KDPNEEITENHNSLKSDENKENSFSADHVTTAVEKSKESQVTADDLEEEKAKAELIMD-- 324
++P EE LKS+E +E + ++ +E ++ ++ EEE+ + L +
Sbjct: 623 EEPEEE--RRQQLLKSEEQEERR--QQQLRREQQERREQRLKREE-EEERLEQRLKREHE 677
Query: 325 DDRTVDPLLSKSQSILISTSATASSKKTIEDRNIKNKKSTNNRASSASARLMTSEFLKKS 384
++R L + Q +++ I+ R K + + A + +++ S K+
Sbjct: 678 EERREQELAEEEQE---------QARERIKSRIPKWQWQLESEADARQSKVY-SRPRKQE 727
Query: 385 SSKRRTPSTTTSSHYLGTLKVLDQKPSQKQSIEPDRADNIRAAVYQEWLEKKNVYLHEMH 444
+RR L+ +++ + +Q E ++ R +Q E+K+ E
Sbjct: 728 GQRRRQEQEEKRRRRESELQWQEEERAHRQQQEEEQR---RDFTWQWQAEEKS----ERG 780
Query: 445 RIKRIESENLRIQNE-QKKAAKREEALASFEAWKAMKEKEAKKIAAKKRLEEKNKKK--T 501
R + LR Q E Q +A +R++ F + E+E K+ ++R E + + +
Sbjct: 781 RQRLSARPPLREQRERQLRAEERQQREQRF-----LPEEEEKEQRRRQRREREKELQFLE 835
Query: 502 EEENAARKGEALQAFEKWKEKKMEYLKEKNRKEREYERAKKQKEEETVAEKKKDNLTAVE 561
EEE R+ A Q E+ + + + +++++R ++ + Q EEE ++++ L A
Sbjct: 836 EEEQLQRRERAQQLQEEEDGLQEDQERRRSQEQRRDQKWRWQLEEER--KRRRHTLYAKP 893
Query: 562 KWNE--KKEAFFKQKEKEKINEKRKEELKRAEKKDK---DKQAINEYEKWL----ENKEK 612
E +KE Q+E+E++ + +E+ +R E++ + ++Q E E+ L E + +
Sbjct: 894 ALQEQLRKEQQLLQEEEEELQREEREKRRRQEQERQYREEEQLQQEEEQLLREEREKRRR 953
Query: 613 QERIERKQKKRHSFLESE 630
QER ER+ +K + E
Sbjct: 954 QER-ERQYRKDKKLQQKE 970
Score = 47.0 bits (110), Expect = 5e-05
Identities = 47/219 (21%), Positives = 109/219 (49%), Gaps = 24/219 (10%)
Query: 430 QEWLEKKNVYLHEMHRIKRIESENLRIQNEQKKAAKREEALASFEAWKAMKEKEA---KK 486
+++LE++ L R ++ + LR Q ++K + E+ L + + ++E ++
Sbjct: 1485 RKFLEEEQ-QLRRQERDRKFREQELRSQEPERKFLEEEQQLHRQQRQRKFLQEEQQLRRQ 1543
Query: 487 IAAKKRLEEKNKKKTEEENAARKGEALQAFEKWKEKKMEYLKEKNRKEREYERAKKQKEE 546
++R +++++K EEE ++ E Q + +++K L+E+ + +E ER K ++E
Sbjct: 1544 ERGQQRRQDRDRKFREEEQLRQEREEQQLSRQERDRKFR-LEEQKVRRQEQER-KFMEDE 1601
Query: 547 ETVAEKKKDNLTAVEKWNEKKEAFFKQKEKEKINEKRKE----------ELKRAEKK--- 593
+ + ++ E+ + +E +E+E+ R+E +L+R E++
Sbjct: 1602 QQLRRQEGQQQLRQERDRKFREDEQLLQEREEQQLHRQERDRKFLEEEPQLRRQEREQQL 1661
Query: 594 --DKDKQAINEYEKWLENKEKQERIERKQKKRHSFLESE 630
D+D++ E E+ L+ E+Q+ R+Q++ F E E
Sbjct: 1662 RHDRDRK-FREEEQLLQEGEEQQL--RRQERDRKFREEE 1697
Score = 42.7 bits (99), Expect = 0.001
Identities = 52/272 (19%), Positives = 112/272 (41%), Gaps = 42/272 (15%)
Query: 300 EKSKESQVTADDLEEEKAKAELIMDDDRTVDPLLSKSQSILISTSATASSKKTIEDRNIK 359
E+ ++ L ++ + +L D DR + + L+ ++ DR +
Sbjct: 1640 ERDRKFLEEEPQLRRQEREQQLRHDRDRKF-----REEEQLLQEGEEQQLRRQERDRKFR 1694
Query: 360 NKKSTNNRASSASARLMTSEFLKKSSSKRRTPSTTTSSHYLGTLKVLDQKPSQKQSIEPD 419
++ R L + L++ +R+ + L Q+ Q+Q
Sbjct: 1695 EEEQQLRRQERERKFLQEEQQLRRQELERKFREE----------EQLRQETEQEQL---R 1741
Query: 420 RADNIRAAVYQEWL--EKKNVYLHEMHRIKRI-ESENLRIQNEQKKAAKREEALASFEAW 476
R + R + +E L E++ L R ++ E E LR + E+++ +E E
Sbjct: 1742 RQERYRKILEEEQLRPEREEQQLRRQERDRKFREEEQLRQEREEQQLRSQESDRKFREEE 1801
Query: 477 KAMKEKEAKKIAAKKR------------LEEKNKK---------KTEEENAARKGEALQA 515
+ +E+E +++ ++R LEE+ ++ + EE+ A ++ +
Sbjct: 1802 QLRQEREEQQLRPQQRDGKYRWEEEQLQLEEQEQRLRQERDRQYRAEEQFATQEKSRREE 1861
Query: 516 FEKWKEKKMEYLKEKNRKEREYERAKKQKEEE 547
E W+E++ + +E+ RK RE ++QKEE+
Sbjct: 1862 QELWQEEEQKRRQERERKLREEHIRRQQKEEQ 1893
Score = 40.0 bits (92), Expect = 0.007
Identities = 35/176 (19%), Positives = 87/176 (49%), Gaps = 22/176 (12%)
Query: 458 NEQKKAAKREEALASFEAWKAMKEKEAKKIAAKKRLEE-----KNKKKTEEENAARKGEA 512
+E+K+A R + S + +E + + ++LEE + +K+ E+E +GE
Sbjct: 96 DEEKRA--RCDGKESLLQDRRQEEDQRRFEPRDRQLEEEPGQRRRQKRQEQERELAEGEE 153
Query: 513 LQAFEKWKEKKMEYLKEKNRKEREYERAKKQKEEETVAEKKKDNLTAVEKWNEKKEAFFK 572
+ +K E L++++R+ R+ E ++++E + E++ + + E F
Sbjct: 154 -------QSEKQERLEQRDRQRRDEELWRQRQEWQEREERRAEEEQLQSCKGHETEEF-- 204
Query: 573 QKEKEKINEKRKEELKRAEKKDKDKQAINEYEKWLENKE-----KQERIERKQKKR 623
++E++ + EL+R +++K +Q ++ + +E K+E + RK++++
Sbjct: 205 -PDEEQLRRRELLELRRKGREEKQQQRRERQDRVFQEEEEKEWRKRETVLRKEEEK 259
>gi|134948605 ankyrin repeat domain 12 isoform 2 [Homo sapiens]
Length = 2039
Score = 74.7 bits (182), Expect = 2e-13
Identities = 144/661 (21%), Positives = 258/661 (39%), Gaps = 144/661 (21%)
Query: 55 SLGDFSDTSADENSVNKKMNDFHISDDEEKN----------------------------- 85
+L ++ D+ +NK ++D HI E++
Sbjct: 334 ALDEYEFKDDDDEEINKMIDDRHILRKEQRKENEPEAEKTHLFAKQEKAFYPKSFKSKKQ 393
Query: 86 -PSKLLFLKTNKSNGNITKDEPV---CAI-----------KNEEEMAPDGCEDIVVKSFS 130
PS++L+ T S+ +++ + C++ K E ++ + + VK
Sbjct: 394 KPSRVLYSSTESSDEEALQNKKISTSCSVIPETSNSDMQTKKEYVVSGEHKQKGKVKRKL 453
Query: 131 ESQNKDEEFEKDKIKMKPKPRILSIKSTSSAENNSLDTDDHFKPSPRPRSMLKKKS---- 186
++QNK++E ++ K + + K + + T+ N LD + + R K
Sbjct: 454 KNQNKNKENQELKQEKEGKE---NTRITNLTVNTGLDCSEKTREEGNFRKSFSPKDDTSL 510
Query: 187 HM---------EEKDGLEDKE-TALSEELELHSAPSSLPTPNGIQLEAEKKAFSENLD-- 234
H+ + GL +K+ T L +E H+ P + + L+ + +
Sbjct: 511 HLFHISTGKSPKHSCGLSEKQSTPLKQE---HTKTCLSPGSSEMSLQPDLVRYDNTESEF 567
Query: 235 -PEDSCLTSLASSSLKQILGD-SFSPGSEGNASGKDPNEEIT-ENHNSLKSDENKENSFS 291
PE S + S + D G + NA KD + T EN + +KE
Sbjct: 568 LPESSSVKSCKHKEKSKHQKDFHLEFGEKSNAKIKDEDHSPTFENSDCTLKKMDKEGKTL 627
Query: 292 ADHVTTAVEKSKESQVTADDLEEEKAKA-------------------ELIMDDDRTVDPL 332
H E+ KE + E+EK K E D T D
Sbjct: 628 KKHKLKHKEREKEKHKKEIEGEKEKYKTKDSAKELQRSVEFDREFWKENFFKSDETEDLF 687
Query: 333 LSKSQSILISTSATASSKKTIEDRNIKNKKSTNNRASSASARLMTS-EFLKKSSSKRRTP 391
L+ L KK+ ++NIK+ KST + S + +KK S K
Sbjct: 688 LNMEHESL------TLEKKSKLEKNIKDDKSTKEKHVSKERNFKEERDKIKKESEKSFRE 741
Query: 392 STTTSSHYLGTLKVLDQKPSQKQSIEPDRADNIRAAVYQEWLEKKNVYLHEMHRIKRIES 451
K+ D K ++++I D+ D+ ++ +E+ ++ LH + + IE
Sbjct: 742 E-----------KIKDLK-EERENIPTDK-DSEFTSLGMSAIEE-SIGLHLVEKEIDIEK 787
Query: 452 ENLRIQNEQKKAAKREEALASFEAWKAMKEKEAKKIAAKKRLEEKNKKKTEEENAARKGE 511
+ I+ ++K KR + +KEK+ +K+ +K E++ K K E ++ K +
Sbjct: 788 QEKHIKESKEKPEKRSQ----------IKEKDIEKME-RKTFEKEKKIKHEHKSEKDKLD 836
Query: 512 ALQAFEKWKEKKMEYLKEKNRKEREYERAKKQKEEETVAEKKKDNLTAVEKWNEKKEAFF 571
+ +K KEK Y + +E E++K T A KK D+ EK EK +
Sbjct: 837 LSECVDKIKEKDKLYSHHTEKCHKEGEKSKN-----TAAIKKTDDR---EKSREKMD--- 885
Query: 572 KQKEKEKINEKRKEELKRAEKKD------KDKQAIN-EYEKWL--ENKEKQERIERKQKK 622
++ EK ++E AE K+ K+KQ+ N EY K +NKEK +++K+K
Sbjct: 886 ----RKHDKEKPEKERHLAESKEKHLMEKKNKQSDNSEYSKSEKGKNKEKDRELDKKEKS 941
Query: 623 R 623
R
Sbjct: 942 R 942
Score = 69.7 bits (169), Expect = 8e-12
Identities = 128/633 (20%), Positives = 242/633 (38%), Gaps = 131/633 (20%)
Query: 48 FDSDEIVSLGDFSDT-SADENSVNKKMNDFHISDDEEKNPSKLLFLKTNKSNGNITKDEP 106
+D+ E L + S S +K DFH+ E+ N K + + T +
Sbjct: 560 YDNTESEFLPESSSVKSCKHKEKSKHQKDFHLEFGEKSNA------KIKDEDHSPTFENS 613
Query: 107 VCAIKNEEEMAPDGCEDIVVKSFSESQNKDEEFEKDKIKMKPKPRILSIKSTSSAENN-- 164
C +K ++ + + E + +E E +K K K K ++ + +
Sbjct: 614 DCTLKKMDKEGKTLKKHKLKHKEREKEKHKKEIEGEKEKYKTKDSAKELQRSVEFDREFW 673
Query: 165 ------SLDTDDHFKPSPRPRSMLKKKSHMEE--KDGLEDKETALSEELELHSAPSSLPT 216
S +T+D F L+KKS +E+ KD KE +S+E +
Sbjct: 674 KENFFKSDETEDLFLNMEHESLTLEKKSKLEKNIKDDKSTKEKHVSKERNFKEERDKIKK 733
Query: 217 PNGIQLEAEK----KAFSENLDPE-DSCLTSLASSSLKQILGDSFSPGSEGNASGKDPNE 271
+ EK K EN+ + DS TSL S++++ +G
Sbjct: 734 ESEKSFREEKIKDLKEERENIPTDKDSEFTSLGMSAIEESIG-----------------L 776
Query: 272 EITENHNSLKSDENKENSFSADHVTTAVEK-SKESQVTADDLE---------EEKAKAEL 321
+ E ++ E H+ + EK K SQ+ D+E E+K K E
Sbjct: 777 HLVEKEIDIEKQEK--------HIKESKEKPEKRSQIKEKDIEKMERKTFEKEKKIKHEH 828
Query: 322 IMDDDRT-----VDPLLSKSQSILISTSATASSKKTIEDRNIKNKKSTNNRASSASARLM 376
+ D+ VD + K + L S K+ + +N K T++R
Sbjct: 829 KSEKDKLDLSECVDKIKEKDK--LYSHHTEKCHKEGEKSKNTAAIKKTDDR--------- 877
Query: 377 TSEFLKKSSSKRRTPSTTTSSHYLGTLKVLDQKPSQKQSIEPDRADNIRAAVYQEWLEKK 436
+KS K +D+K +++ P++ ++ + + +EKK
Sbjct: 878 -----EKSREK------------------MDRKHDKEK---PEKERHLAESKEKHLMEKK 911
Query: 437 NVYLHEMHRIKRIESENLRIQNEQKKAAKREEALASFEAWKAMKEKEAKKIAAKKRLEEK 496
N +S+N +K K +E + + ++KE+ I K ++E+
Sbjct: 912 NK-----------QSDNSEYSKSEK--GKNKEKDRELDKKEKSRDKESINITNSKHIQEE 958
Query: 497 NKKKTEEENAARKGEALQAFEKWKEKKMEYL--KEKNRKEREYERAKKQKEEE------- 547
K + N A+ + L EK K++ ++ KEK++K+++ +R K++ + +
Sbjct: 959 KKSSIVDGNKAQHEKPLSLKEKTKDEPLKTPDGKEKDKKDKDIDRYKERDKHKDKIQINS 1018
Query: 548 -----TVAEKKKDNLTAVEKWNEKKEAFF-----KQKEKEKINEKRKEELKRAEKKDKDK 597
+ A+K K + K KE Q E++ + E+++ KK K+K
Sbjct: 1019 LLKLKSEADKPKPKSSPASKDTRPKEKRLVNDDLMQTSFERMLSLKDLEIEQWHKKHKEK 1078
Query: 598 QAINEYEKWLENKEKQERIERKQKKRHSFLESE 630
E E+ + +I+ K+K +H+ ES+
Sbjct: 1079 IKQKEKERLRNRNCLELKIKDKEKTKHTPTESK 1111
Score = 59.7 bits (143), Expect = 8e-09
Identities = 117/540 (21%), Positives = 216/540 (40%), Gaps = 69/540 (12%)
Query: 110 IKNEEEMAPDGCEDIVVKSFSESQNKDEEFEKDKIKMKPKPRILSIKSTSSAENN---SL 166
+ +++E D E V S +N D E EKD + + K + S SA +
Sbjct: 283 LSDDDESYTDSEEAQSVNPSSVDENIDSETEKDSLICESKQILPSKTPLPSALDEYEFKD 342
Query: 167 DTDDHFKPSPRPRSMLKKKSHMEEKDGLEDKETALSEELELHSAPSSLPTPNGIQLEAEK 226
D D+ R +L+K+ E + E ++T L + E P S + + + +
Sbjct: 343 DDDEEINKMIDDRHILRKEQRKENEP--EAEKTHLFAKQEKAFYPKSFKSK---KQKPSR 397
Query: 227 KAFSENLDPEDSCLTSLASSSLKQILGDSFSPGSEGNASGKDPNEEITENHNSLKSDENK 286
+S ++ L + S+ ++ ++ N ++ + S E+K
Sbjct: 398 VLYSSTESSDEEALQNKKISTSCSVIPET-------------SNSDMQTKKEYVVSGEHK 444
Query: 287 ENSFSADHVTTAVEKSKESQVTADDLEEEKAKAELIMDDDRTVDPLLSKSQSILISTSAT 346
+ K+KE+Q +L++EK E + TV+ L
Sbjct: 445 QKG-KVKRKLKNQNKNKENQ----ELKQEKEGKENTRITNLTVNTGLD------------ 487
Query: 347 ASSKKTIEDRNIKNKKSTNNRASSASARLMTSEFLKKSSSKRRTPSTTTSSHYLGTLKVL 406
S+KT E+ N + S + S + T + K S ST + T
Sbjct: 488 -CSEKTREEGNFRKSFSPKDDTSLHLFHISTGKSPKHSCGLSEKQSTPLKQEHTKTCL-- 544
Query: 407 DQKPSQKQSIEPD--RADNIRAAVYQEWLEKKNVYLHEMHRIKRIESENLRIQNEQKKAA 464
S + S++PD R DN + E+L + + H+ K ++ ++ +K A
Sbjct: 545 -SPGSSEMSLQPDLVRYDNTES----EFLPESSSVKSCKHKEKSKHQKDFHLEFGEKSNA 599
Query: 465 K--REEALASFE----AWKAMKEKEAK-----KIAAKKRLEEKNKKKTEEENAARKG-EA 512
K E+ +FE K M +KE K K+ K+R +EK+KK+ E E K ++
Sbjct: 600 KIKDEDHSPTFENSDCTLKKM-DKEGKTLKKHKLKHKEREKEKHKKEIEGEKEKYKTKDS 658
Query: 513 LQAFEKWKEKKMEYLKEKNRKEREYERAKKQKEEETVAEKKKDNLTAVEKWNEKKEAFFK 572
+ ++ E E+ KE K E E E E++ +KK L EK K
Sbjct: 659 AKELQRSVEFDREFWKENFFKSDETEDLFLNMEHESLTLEKKSKL-------EKNIKDDK 711
Query: 573 QKEKEKINEKRKEELKRAEKKDKDKQAINEYEKWLENKEKQERIERKQKKRHSFLESEAL 632
+++ ++++R + +R + K + +++ E EK + KE++E I + + L A+
Sbjct: 712 STKEKHVSKERNFKEERDKIKKESEKSFRE-EKIKDLKEERENIPTDKDSEFTSLGMSAI 770
>gi|134948558 ankyrin repeat domain 12 isoform 1 [Homo sapiens]
Length = 2062
Score = 74.7 bits (182), Expect = 2e-13
Identities = 144/661 (21%), Positives = 258/661 (39%), Gaps = 144/661 (21%)
Query: 55 SLGDFSDTSADENSVNKKMNDFHISDDEEKN----------------------------- 85
+L ++ D+ +NK ++D HI E++
Sbjct: 357 ALDEYEFKDDDDEEINKMIDDRHILRKEQRKENEPEAEKTHLFAKQEKAFYPKSFKSKKQ 416
Query: 86 -PSKLLFLKTNKSNGNITKDEPV---CAI-----------KNEEEMAPDGCEDIVVKSFS 130
PS++L+ T S+ +++ + C++ K E ++ + + VK
Sbjct: 417 KPSRVLYSSTESSDEEALQNKKISTSCSVIPETSNSDMQTKKEYVVSGEHKQKGKVKRKL 476
Query: 131 ESQNKDEEFEKDKIKMKPKPRILSIKSTSSAENNSLDTDDHFKPSPRPRSMLKKKS---- 186
++QNK++E ++ K + + K + + T+ N LD + + R K
Sbjct: 477 KNQNKNKENQELKQEKEGKE---NTRITNLTVNTGLDCSEKTREEGNFRKSFSPKDDTSL 533
Query: 187 HM---------EEKDGLEDKE-TALSEELELHSAPSSLPTPNGIQLEAEKKAFSENLD-- 234
H+ + GL +K+ T L +E H+ P + + L+ + +
Sbjct: 534 HLFHISTGKSPKHSCGLSEKQSTPLKQE---HTKTCLSPGSSEMSLQPDLVRYDNTESEF 590
Query: 235 -PEDSCLTSLASSSLKQILGD-SFSPGSEGNASGKDPNEEIT-ENHNSLKSDENKENSFS 291
PE S + S + D G + NA KD + T EN + +KE
Sbjct: 591 LPESSSVKSCKHKEKSKHQKDFHLEFGEKSNAKIKDEDHSPTFENSDCTLKKMDKEGKTL 650
Query: 292 ADHVTTAVEKSKESQVTADDLEEEKAKA-------------------ELIMDDDRTVDPL 332
H E+ KE + E+EK K E D T D
Sbjct: 651 KKHKLKHKEREKEKHKKEIEGEKEKYKTKDSAKELQRSVEFDREFWKENFFKSDETEDLF 710
Query: 333 LSKSQSILISTSATASSKKTIEDRNIKNKKSTNNRASSASARLMTS-EFLKKSSSKRRTP 391
L+ L KK+ ++NIK+ KST + S + +KK S K
Sbjct: 711 LNMEHESL------TLEKKSKLEKNIKDDKSTKEKHVSKERNFKEERDKIKKESEKSFRE 764
Query: 392 STTTSSHYLGTLKVLDQKPSQKQSIEPDRADNIRAAVYQEWLEKKNVYLHEMHRIKRIES 451
K+ D K ++++I D+ D+ ++ +E+ ++ LH + + IE
Sbjct: 765 E-----------KIKDLK-EERENIPTDK-DSEFTSLGMSAIEE-SIGLHLVEKEIDIEK 810
Query: 452 ENLRIQNEQKKAAKREEALASFEAWKAMKEKEAKKIAAKKRLEEKNKKKTEEENAARKGE 511
+ I+ ++K KR + +KEK+ +K+ +K E++ K K E ++ K +
Sbjct: 811 QEKHIKESKEKPEKRSQ----------IKEKDIEKME-RKTFEKEKKIKHEHKSEKDKLD 859
Query: 512 ALQAFEKWKEKKMEYLKEKNRKEREYERAKKQKEEETVAEKKKDNLTAVEKWNEKKEAFF 571
+ +K KEK Y + +E E++K T A KK D+ EK EK +
Sbjct: 860 LSECVDKIKEKDKLYSHHTEKCHKEGEKSKN-----TAAIKKTDDR---EKSREKMD--- 908
Query: 572 KQKEKEKINEKRKEELKRAEKKD------KDKQAIN-EYEKWL--ENKEKQERIERKQKK 622
++ EK ++E AE K+ K+KQ+ N EY K +NKEK +++K+K
Sbjct: 909 ----RKHDKEKPEKERHLAESKEKHLMEKKNKQSDNSEYSKSEKGKNKEKDRELDKKEKS 964
Query: 623 R 623
R
Sbjct: 965 R 965
Score = 69.7 bits (169), Expect = 8e-12
Identities = 128/633 (20%), Positives = 242/633 (38%), Gaps = 131/633 (20%)
Query: 48 FDSDEIVSLGDFSDT-SADENSVNKKMNDFHISDDEEKNPSKLLFLKTNKSNGNITKDEP 106
+D+ E L + S S +K DFH+ E+ N K + + T +
Sbjct: 583 YDNTESEFLPESSSVKSCKHKEKSKHQKDFHLEFGEKSNA------KIKDEDHSPTFENS 636
Query: 107 VCAIKNEEEMAPDGCEDIVVKSFSESQNKDEEFEKDKIKMKPKPRILSIKSTSSAENN-- 164
C +K ++ + + E + +E E +K K K K ++ + +
Sbjct: 637 DCTLKKMDKEGKTLKKHKLKHKEREKEKHKKEIEGEKEKYKTKDSAKELQRSVEFDREFW 696
Query: 165 ------SLDTDDHFKPSPRPRSMLKKKSHMEE--KDGLEDKETALSEELELHSAPSSLPT 216
S +T+D F L+KKS +E+ KD KE +S+E +
Sbjct: 697 KENFFKSDETEDLFLNMEHESLTLEKKSKLEKNIKDDKSTKEKHVSKERNFKEERDKIKK 756
Query: 217 PNGIQLEAEK----KAFSENLDPE-DSCLTSLASSSLKQILGDSFSPGSEGNASGKDPNE 271
+ EK K EN+ + DS TSL S++++ +G
Sbjct: 757 ESEKSFREEKIKDLKEERENIPTDKDSEFTSLGMSAIEESIG-----------------L 799
Query: 272 EITENHNSLKSDENKENSFSADHVTTAVEK-SKESQVTADDLE---------EEKAKAEL 321
+ E ++ E H+ + EK K SQ+ D+E E+K K E
Sbjct: 800 HLVEKEIDIEKQEK--------HIKESKEKPEKRSQIKEKDIEKMERKTFEKEKKIKHEH 851
Query: 322 IMDDDRT-----VDPLLSKSQSILISTSATASSKKTIEDRNIKNKKSTNNRASSASARLM 376
+ D+ VD + K + L S K+ + +N K T++R
Sbjct: 852 KSEKDKLDLSECVDKIKEKDK--LYSHHTEKCHKEGEKSKNTAAIKKTDDR--------- 900
Query: 377 TSEFLKKSSSKRRTPSTTTSSHYLGTLKVLDQKPSQKQSIEPDRADNIRAAVYQEWLEKK 436
+KS K +D+K +++ P++ ++ + + +EKK
Sbjct: 901 -----EKSREK------------------MDRKHDKEK---PEKERHLAESKEKHLMEKK 934
Query: 437 NVYLHEMHRIKRIESENLRIQNEQKKAAKREEALASFEAWKAMKEKEAKKIAAKKRLEEK 496
N +S+N +K K +E + + ++KE+ I K ++E+
Sbjct: 935 NK-----------QSDNSEYSKSEK--GKNKEKDRELDKKEKSRDKESINITNSKHIQEE 981
Query: 497 NKKKTEEENAARKGEALQAFEKWKEKKMEYL--KEKNRKEREYERAKKQKEEE------- 547
K + N A+ + L EK K++ ++ KEK++K+++ +R K++ + +
Sbjct: 982 KKSSIVDGNKAQHEKPLSLKEKTKDEPLKTPDGKEKDKKDKDIDRYKERDKHKDKIQINS 1041
Query: 548 -----TVAEKKKDNLTAVEKWNEKKEAFF-----KQKEKEKINEKRKEELKRAEKKDKDK 597
+ A+K K + K KE Q E++ + E+++ KK K+K
Sbjct: 1042 LLKLKSEADKPKPKSSPASKDTRPKEKRLVNDDLMQTSFERMLSLKDLEIEQWHKKHKEK 1101
Query: 598 QAINEYEKWLENKEKQERIERKQKKRHSFLESE 630
E E+ + +I+ K+K +H+ ES+
Sbjct: 1102 IKQKEKERLRNRNCLELKIKDKEKTKHTPTESK 1134
Score = 59.7 bits (143), Expect = 8e-09
Identities = 117/540 (21%), Positives = 216/540 (40%), Gaps = 69/540 (12%)
Query: 110 IKNEEEMAPDGCEDIVVKSFSESQNKDEEFEKDKIKMKPKPRILSIKSTSSAENN---SL 166
+ +++E D E V S +N D E EKD + + K + S SA +
Sbjct: 306 LSDDDESYTDSEEAQSVNPSSVDENIDSETEKDSLICESKQILPSKTPLPSALDEYEFKD 365
Query: 167 DTDDHFKPSPRPRSMLKKKSHMEEKDGLEDKETALSEELELHSAPSSLPTPNGIQLEAEK 226
D D+ R +L+K+ E + E ++T L + E P S + + + +
Sbjct: 366 DDDEEINKMIDDRHILRKEQRKENEP--EAEKTHLFAKQEKAFYPKSFKSK---KQKPSR 420
Query: 227 KAFSENLDPEDSCLTSLASSSLKQILGDSFSPGSEGNASGKDPNEEITENHNSLKSDENK 286
+S ++ L + S+ ++ ++ N ++ + S E+K
Sbjct: 421 VLYSSTESSDEEALQNKKISTSCSVIPET-------------SNSDMQTKKEYVVSGEHK 467
Query: 287 ENSFSADHVTTAVEKSKESQVTADDLEEEKAKAELIMDDDRTVDPLLSKSQSILISTSAT 346
+ K+KE+Q +L++EK E + TV+ L
Sbjct: 468 QKG-KVKRKLKNQNKNKENQ----ELKQEKEGKENTRITNLTVNTGLD------------ 510
Query: 347 ASSKKTIEDRNIKNKKSTNNRASSASARLMTSEFLKKSSSKRRTPSTTTSSHYLGTLKVL 406
S+KT E+ N + S + S + T + K S ST + T
Sbjct: 511 -CSEKTREEGNFRKSFSPKDDTSLHLFHISTGKSPKHSCGLSEKQSTPLKQEHTKTCL-- 567
Query: 407 DQKPSQKQSIEPD--RADNIRAAVYQEWLEKKNVYLHEMHRIKRIESENLRIQNEQKKAA 464
S + S++PD R DN + E+L + + H+ K ++ ++ +K A
Sbjct: 568 -SPGSSEMSLQPDLVRYDNTES----EFLPESSSVKSCKHKEKSKHQKDFHLEFGEKSNA 622
Query: 465 K--REEALASFE----AWKAMKEKEAK-----KIAAKKRLEEKNKKKTEEENAARKG-EA 512
K E+ +FE K M +KE K K+ K+R +EK+KK+ E E K ++
Sbjct: 623 KIKDEDHSPTFENSDCTLKKM-DKEGKTLKKHKLKHKEREKEKHKKEIEGEKEKYKTKDS 681
Query: 513 LQAFEKWKEKKMEYLKEKNRKEREYERAKKQKEEETVAEKKKDNLTAVEKWNEKKEAFFK 572
+ ++ E E+ KE K E E E E++ +KK L EK K
Sbjct: 682 AKELQRSVEFDREFWKENFFKSDETEDLFLNMEHESLTLEKKSKL-------EKNIKDDK 734
Query: 573 QKEKEKINEKRKEELKRAEKKDKDKQAINEYEKWLENKEKQERIERKQKKRHSFLESEAL 632
+++ ++++R + +R + K + +++ E EK + KE++E I + + L A+
Sbjct: 735 STKEKHVSKERNFKEERDKIKKESEKSFRE-EKIKDLKEERENIPTDKDSEFTSLGMSAI 793
>gi|56676397 ankyrin repeat domain 11 [Homo sapiens]
Length = 2663
Score = 74.3 bits (181), Expect = 3e-13
Identities = 140/586 (23%), Positives = 233/586 (39%), Gaps = 93/586 (15%)
Query: 99 GNITKDEPVCAIKNEEEMAPDGCEDIVVKSFSESQNKDEEFEKD-KIKMK-PKPRILSIK 156
G T E +EEE AP S + N D EFEK K K K P+P+ +
Sbjct: 287 GTYTSSEESSTESSEEEDAPS----FAPSSSVDGNNTDSEFEKGLKHKAKNPEPQKATAP 342
Query: 157 STSSAENNSLDTDDHFKPSPRPRSMLKKKSHMEEKDGLEDKETALSEELELHSAPSSLPT 216
E + D D P H+ +KD KET + + + T
Sbjct: 343 VKDEYEFDEDDEQDRVPPVD--------DKHLLKKD--YRKETKSNSFISIPKMEVKSYT 392
Query: 217 PNGI--QLEAEKKAFSENLDPEDSCLTSLASSSLKQILGDSFSPGSEGN--ASGKDPNEE 272
N +A + S+ D ED+ +T L+ + + PGS+ ++ K E+
Sbjct: 393 KNNTIAPKKASHRILSDTSDEEDASVTVGTGEKLR-LSAHTILPGSKTREPSNAKQQKEK 451
Query: 273 ITENHNSLKSDENKENSFS--ADHVTTAVEKSKESQVTADDLEEEKA----KAELIMDDD 326
K + +E F +D ++ +S+ S+ DD + + K ++ D
Sbjct: 452 NKVKKKRKKETKGREVRFGKRSDKFCSSESESESSESGEDDRDSLGSSGCLKGSPLVLKD 511
Query: 327 RTVDPLLSKSQSILISTSATASSKKTIEDRNIKNKKSTNNRASSASARLMTSEFLKKSSS 386
++ LS S + +SA + D++ K+ ++ N + S+ A S S
Sbjct: 512 PSLFSSLSASSTSSHGSSAAQKQNPSHTDQHTKHWRTDNWKTISSPAWSEVSSL----SD 567
Query: 387 KRRTPSTTTSSHYLGTLKVLDQKPSQKQSIEPDRAD----------NIRAAVYQEWLEKK 436
RT T+ S + V KP +K+ RA + AV + E K
Sbjct: 568 STRTRLTSESDYSSEGSSVESLKPVRKRQEHRKRASLSEKKSPFLSSAEGAVPKLDKEGK 627
Query: 437 NVYLHEM-HRIKRIESENLRIQNEQK----------------KAAKREEALASFEAWKAM 479
V H+ H+ K E I E K KA E L++ K +
Sbjct: 628 VVKKHKTKHKHKNKEKGQCSISQELKLKSFTYEYEDSKQKSDKAILLENDLSTENKLKVL 687
Query: 480 KE-----KEAKKIAAKKRLEEKNKKKTEEENAAR----KGEALQAFEKWKEK-----KME 525
K K+ +K++ K +LEEK +E++ R + ++F + K++ K
Sbjct: 688 KHDRDHFKKEEKLS-KMKLEEKEWLFKDEKSLKRIKDTNKDISRSFREEKDRSNKAEKER 746
Query: 526 YLKEKNRKEREY-----ERAKKQKEEETVAEKKKDNLTAVEKWNEKKEAFFKQKEKEKIN 580
LKEK+ KE + ER KK K+ + EKK D +K +++KE FK+
Sbjct: 747 SLKEKSPKEEKLRLYKEERKKKSKDRPSKLEKKND--LKEDKISKEKEKIFKED------ 798
Query: 581 EKRKEELKRAEKKDKDKQAINEY---EKWLENKEKQERIERKQKKR 623
KE+LK+ EK ++ A +EY ++LEN++ + + Q+ R
Sbjct: 799 ---KEKLKK-EKVYREDSAFDEYCNKNQFLENEDTKFSLSDDQRDR 840
Score = 61.2 bits (147), Expect = 3e-09
Identities = 124/602 (20%), Positives = 227/602 (37%), Gaps = 77/602 (12%)
Query: 80 DDEEKNPSKLLFLKTNKSNGNITKDEPVCAIKNEEE--MAPDGCEDIVVKSFSESQNKDE 137
+++ +KL LK ++ + K+E + +K EE+ + D +K ++ ++
Sbjct: 675 ENDLSTENKLKVLKHDRDH--FKKEEKLSKMKLEEKEWLFKDEKSLKRIKDTNKDISRSF 732
Query: 138 EFEKDKIKMKPKPRILSIKSTSSAENNSLDTDDHFKPSPRPRSMLKKKSHMEEKDGLEDK 197
EKD+ K R L KS + + K RP S L+KK+ ++E ++K
Sbjct: 733 REEKDRSNKAEKERSLKEKSPKEEKLRLYKEERKKKSKDRP-SKLEKKNDLKEDKISKEK 791
Query: 198 ETALSEELELHSAPSSLPTPNGIQLEAEKKAFSENLDPEDSCLTSLASSSLKQILGDSFS 257
E E+ E + K F EN D + S + SF
Sbjct: 792 EKIFKEDKEKLKKEKVYREDSAFDEYCNKNQFLENEDTKFSLSDDQRDRWFSDLSDSSF- 850
Query: 258 PGSEGNASGKDPNEEITENHNSLKSDENKENSFSADHVTTAVEKSKESQVTADDLEEEKA 317
+ G+D + ++ +KSD S + + T E SKE + + E+
Sbjct: 851 -----DFKGEDSWDSPVTDYRDMKSD-----SVAKLILETVKEDSKERRRDSRAREKRDY 900
Query: 318 KAELIMDDDRTVDPLLSKSQSILISTSATASSKKTIEDRNIKNKKSTN------------ 365
+ DR D L S+ T S + +++ K ++S
Sbjct: 901 REPFFRKKDR--DYLDKNSEKRKEQTEKHKSVPGYLSEKDKKRRESAEAGRDRKDALESC 958
Query: 366 --NRASSASARLMTSEFLKKSSSKRRTPSTTTSSHYLGTLKVLDQKPSQ----KQSIEPD 419
R A E LK+ + + G P++ K + +
Sbjct: 959 KERRDGRAKPEEAHREELKECGCESGFKDKSDGDFGKGLEPWERHHPAREKEKKDGPDKE 1018
Query: 420 RADNIRAAVYQEWLEKKNV----YLHEMHRIKRIES---ENLRIQNEQKKA-AKREEALA 471
R + + Y+E K+ L + + K + E + + K K +E A
Sbjct: 1019 RKEKTKPERYKEKSSDKDKSEKSILEKCQKDKEFDKCFKEKKDTKEKHKDTHGKDKERKA 1078
Query: 472 SFEAWKAMKEKEAKKIAAKKRLEEKNKKKTEEEN---------------------AARKG 510
S + K KEK I ++ E+K+ KK +E++ + G
Sbjct: 1079 SLDQGKEKKEKAFPGIISEDFSEKKDDKKGKEKSWYIADIFTDESEDDRDSCMGSGFKMG 1138
Query: 511 EA-----LQAFEKWKEKKMEYLKEKNRKEREYERAKKQKEEETVAEKKKDNLTAVEKWNE 565
EA ++ +E + Y +++RK + + ++QK++E +++KD A ++
Sbjct: 1139 EASDLPRTDGLQEKEEGREAYASDRHRKSSDKQHPERQKDKEP-RDRRKDRGAADAGRDK 1197
Query: 566 KKEAFFKQKEK--EKINEKRKEELKRAE-KKDKDKQAINEYEKWLENKEKQERIERKQKK 622
K++ F K KEK ++ EK K+ RA +DK+ +K E EK+ E K K
Sbjct: 1198 KEKVFEKHKEKKDKESTEKYKDRKDRASVDSTQDKK---NKQKLPEKAEKKHAAEDKAKS 1254
Query: 623 RH 624
+H
Sbjct: 1255 KH 1256
Score = 60.5 bits (145), Expect = 5e-09
Identities = 135/641 (21%), Positives = 246/641 (38%), Gaps = 96/641 (14%)
Query: 42 SEYSDDFDSDEIVSLGDFSDTSADENSVNKKMND-FHISDDEEKNPSKLLFLKTNKSNGN 100
S+ SD+ D+ V G+ SA K + + +EKN K K
Sbjct: 408 SDTSDEEDASVTVGTGEKLRLSAHTILPGSKTREPSNAKQQKEKN-------KVKKKRKK 460
Query: 101 ITKDEPVCAIKNEEEMAPDGCEDIVVKSFSESQNKDEEFEKDKIKMKPKPRIL------- 153
TK V K ++ C SES D + +K P +L
Sbjct: 461 ETKGREVRFGKRSDKF----CSSESESESSESGEDDRDSLGSSGCLKGSPLVLKDPSLFS 516
Query: 154 --SIKSTSS------AENNSLDTDDHFKPSPRPRSMLKKKSHMEEKDGLEDK-ETALSEE 204
S STSS + N TD H K E L D T L+ E
Sbjct: 517 SLSASSTSSHGSSAAQKQNPSHTDQHTKHWRTDNWKTISSPAWSEVSSLSDSTRTRLTSE 576
Query: 205 LELHSAPSSLPTPNGIQLEAEKKAFSENLDPEDSCLTSLASSSLKQILGDSFSPGSEGNA 264
+ S SS+ + ++ E + AS S K+ F +EG
Sbjct: 577 SDYSSEGSSVESLKPVRKRQEHR--------------KRASLSEKK---SPFLSSAEGAV 619
Query: 265 SGKDPNEEITENHNSLKSDENKENSFSADHVTTAVEKSKESQVTADDLEEEKAKAELIMD 324
D ++ + H + +NKE + + K K +D +++ KA L+ +
Sbjct: 620 PKLDKEGKVVKKHKTKHKHKNKEKGQCS---ISQELKLKSFTYEYEDSKQKSDKAILLEN 676
Query: 325 DDRTVDPLLSKSQSILISTSATASSKKTIEDR--------NIKNKKSTNNRASSA--SAR 374
D T + L SK +E++ ++K K TN S + +
Sbjct: 677 DLSTENKLKVLKHDRDHFKKEEKLSKMKLEEKEWLFKDEKSLKRIKDTNKDISRSFREEK 736
Query: 375 LMTSEFLKKSSSKRRTPSTTTSSHYLGTLKVLDQ----KPSQKQSIEPDRADNIRAAVYQ 430
+++ K+ S K ++P Y K + K +K ++ D+ + +++
Sbjct: 737 DRSNKAEKERSLKEKSPKEEKLRLYKEERKKKSKDRPSKLEKKNDLKEDKISKEKEKIFK 796
Query: 431 E---WLEKKNVYLHEM------HRIKRIESENLR--IQNEQKKAAKREEALASFE----- 474
E L+K+ VY + ++ + +E+E+ + + ++Q+ + + +SF+
Sbjct: 797 EDKEKLKKEKVYREDSAFDEYCNKNQFLENEDTKFSLSDDQRDRWFSDLSDSSFDFKGED 856
Query: 475 AWKA-------MKEKEAKKIAAKKRLEEKNKKKTEEENAARKGEALQAFEKWKEKKMEYL 527
+W + MK K+ + ++E +K++ + A K + + F +++K +YL
Sbjct: 857 SWDSPVTDYRDMKSDSVAKLILET-VKEDSKERRRDSRAREKRDYREPF--FRKKDRDYL 913
Query: 528 KEKNRKEREYERAKKQKEEETVAEKKKDNLTAVEKWNEKKEAFFKQKEKE----KINEKR 583
+KN ++R+ + K + ++EK K + E ++K+A KE+ K E
Sbjct: 914 -DKNSEKRKEQTEKHKSVPGYLSEKDKKRRESAEAGRDRKDALESCKERRDGRAKPEEAH 972
Query: 584 KEELKR--AEKKDKDKQAINEYEKWLENKEKQERIERKQKK 622
+EELK E KDK + ++ K LE E+ K+KK
Sbjct: 973 REELKECGCESGFKDK-SDGDFGKGLEPWERHHPAREKEKK 1012
Score = 54.7 bits (130), Expect = 3e-07
Identities = 126/585 (21%), Positives = 233/585 (39%), Gaps = 68/585 (11%)
Query: 33 TARSARQRSSEYSDDFDSDEIVSLGDFSDTSADENSVNKKMNDFHISDDEEKNPSKLLFL 92
+ R+ S+YS + S E + S+++K + F +S E P
Sbjct: 568 STRTRLTSESDYSSEGSSVESLKPVRKRQEHRKRASLSEKKSPF-LSSAEGAVP------ 620
Query: 93 KTNKSNGNITKDEPVCAIKNEEEMAPDGCEDIVVKSFSESQNKDEEFEKDKIKMKPKPRI 152
K +K + K + KN+E+ +++ +KSF+ +E + K K I
Sbjct: 621 KLDKEGKVVKKHKTKHKHKNKEKGQCSISQELKLKSFT--------YEYEDSKQKSDKAI 672
Query: 153 LSIKSTSSAENNSLDTDDHFKPSPRPRSMLKKKSHMEEKDGLEDKETALSEELELHSAPS 212
L N L T++ K R KK+ + K LE+KE +E L
Sbjct: 673 LL--------ENDLSTENKLKVLKHDRDHFKKEEKLS-KMKLEEKEWLFKDEKSLKRIKD 723
Query: 213 SLPTPNGIQLEAEKKAFSENLDPEDSCLTSLASSSLKQILGDSFSPGSEGNASGKDPNEE 272
+ + + E+K S + E S ++ + S+ S + +
Sbjct: 724 T--NKDISRSFREEKDRSNKAEKERSLKEKSPKEEKLRLYKEERKKKSKDRPSKLEKKND 781
Query: 273 ITENHNSLKSDENKENSFSADHVTTAVEKSKESQVTADDLE-EEKAKAELIMDDDRTVDP 331
+ E+ K + KE F D EK K+ +V +D +E ++++ T
Sbjct: 782 LKED----KISKEKEKIFKEDK-----EKLKKEKVYREDSAFDEYCNKNQFLENEDTKFS 832
Query: 332 LLSKSQSILISTSATASSKKTIEDRNIKNKKSTNNRASSASARLMTSEFLKKSSSKRRTP 391
L + S + +S ED + S + A+L+ E +K+ S +RR
Sbjct: 833 LSDDQRDRWFSDLSDSSFDFKGEDSWDSPVTDYRDMKSDSVAKLIL-ETVKEDSKERRRD 891
Query: 392 STTTSSHYLGTLKVLDQKPSQKQSIEPDRADNIRAAVYQEWLEKKNV--YLHEMHRIKRI 449
S D + + + D D ++ + K+V YL E + +R
Sbjct: 892 SRAREKR--------DYREPFFRKKDRDYLDKNSEKRKEQTEKHKSVPGYLSEKDKKRRE 943
Query: 450 ESENLRIQNEQKKAAKREEALASFEAWKAMKEKEAK-KIAAKKRLEEKN-KKKTEEENAA 507
+E R R++AL E+ K ++ AK + A ++ L+E + ++++
Sbjct: 944 SAEAGR---------DRKDAL---ESCKERRDGRAKPEEAHREELKECGCESGFKDKSDG 991
Query: 508 RKGEALQAFEKWKEKKMEYLKEKNRKEREYERAKKQKEEETVAEKKKDNLTAVEKWNEKK 567
G+ L+ +E+ + + K+ KER+ E+ K ++ +E ++K K + +EK + K
Sbjct: 992 DFGKGLEPWERHHPAREKEKKDGPDKERK-EKTKPERYKEKSSDKDKSEKSILEKCQKDK 1050
Query: 568 EAFFKQKEKEKINEKRKEELKRAEKKDKDKQAINEYEKWLENKEK 612
E KEK+ EK K+ KDK+++A + K E KEK
Sbjct: 1051 EFDKCFKEKKDTKEKHKD----THGKDKERKASLDQGK--EKKEK 1089
Score = 36.6 bits (83), Expect = 0.074
Identities = 101/534 (18%), Positives = 191/534 (35%), Gaps = 88/534 (16%)
Query: 127 KSFSESQNKDEEFEKD-KIKMKPKPRILSIKSTSSAENNSLDTDDHFKPSPRPRSMLKKK 185
KS E KD+EF+K K K K + SLD K P + +
Sbjct: 1040 KSILEKCQKDKEFDKCFKEKKDTKEKHKDTHGKDKERKASLDQGKEKKEKAFPGIISEDF 1099
Query: 186 SHM-EEKDGLE---------------DKETALSEELELHSAPSSLPTPNGIQLEAE-KKA 228
S ++K G E D+++ + ++ A S LP +G+Q + E ++A
Sbjct: 1100 SEKKDDKKGKEKSWYIADIFTDESEDDRDSCMGSGFKMGEA-SDLPRTDGLQEKEEGREA 1158
Query: 229 FSENLDPEDSCLTSLASSSLKQILGDSFSPGSEGNASGKDPNEEITENHNSLKSDEN--- 285
++ + + S K+ G+ +G+D E++ E H K E+
Sbjct: 1159 YASDRHRKSSDKQHPERQKDKEPRDRRKDRGAAD--AGRDKKEKVFEKHKEKKDKESTEK 1216
Query: 286 -KENSFSADHVTTAVEKSKES---QVTADDLEEEKAKAELIMDDDRTVDPLLSKSQSILI 341
K+ A +T +K+K+ + E+KAK++ D+ SK +
Sbjct: 1217 YKDRKDRASVDSTQDKKNKQKLPEKAEKKHAAEDKAKSKHKEKSDKEH----SKERKSSR 1272
Query: 342 STSATASSKKTIEDRNIKN-KKSTNNRASSASARLMTSEFLKKSSSKRRTPSTTTSSHYL 400
S A S + +E+ + ++ +N++ S S+ T + + P T
Sbjct: 1273 SADAEKSLLEKLEEEALHEYREDSNDKISEVSSDSFTD--------RGQEPGLTAFLEVS 1324
Query: 401 GTLKVLDQKPSQKQSIEPDRADNIRAAVYQEWLEKKNVYLHEMHRIKRIESENLRIQNEQ 460
T D KP + +A E L++K + H +
Sbjct: 1325 FTEPPGDDKPRE-------------SACLPEKLKEKERHRHS--------------SSSS 1357
Query: 461 KKAAKREEALASFEAWKAMKEKEAKKIAAKKRLEEKNKKKTEEENAARKGEALQAFEKWK 520
KK+ RE A KK EK +K + + + ++ Q + +
Sbjct: 1358 KKSHDRERA--------------------KKEKAEKKEKGEDYKEGGSRKDSGQYEKDFL 1397
Query: 521 EKKMEYLKEKNRKEREYERAKKQKEEETVAEKKKDNLTAVEKWNEKKEAFFKQKEKEKIN 580
E + + + E E K + T + K D+ K EK+ + +
Sbjct: 1398 EADAYGVSYNMKADIEDELDKTIELFSTEKKDKNDSEREPSKKIEKELKPYGSSAINILK 1457
Query: 581 EKRKEELKRAEKKDKDKQAINEYEKWLENKEKQERIERKQKKRHSFLESEALPP 634
EK+K E R + +D+ ++ + + L + E + + ++ + PP
Sbjct: 1458 EKKKREKHREKWRDEKERHRDRHADGLLRHHRDELLRHHRDEQKPATRDKDSPP 1511
>gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo
sapiens]
Length = 750
Score = 72.8 bits (177), Expect = 9e-13
Identities = 91/372 (24%), Positives = 172/372 (46%), Gaps = 56/372 (15%)
Query: 273 ITENHNSLKSDENKENSFSADHVTTAVEKSKESQVTADDLEEEKAKAELIMDDDRTVDPL 332
I+ H+S K E + SA A +K K + ++L +E+ L + + D
Sbjct: 164 ISRLHDSWKFAGELEQALSA----VATQKKKADRYI-EELTKERDALSLELYRNTITDEE 218
Query: 333 LSKSQSILISTSATASSKKTIEDRNIKNKKSTNNRASSASARLMTSEFLKKSSSKRRTPS 392
L + + L S+K+ N+K K RA L+ + L+ +
Sbjct: 219 LKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKL----LLPQQQLQAEADHLGKEL 274
Query: 393 TTTSSHYLGTLKV------LDQKPSQKQSIEPDRADNIRAAVYQEWLEKKNVYLHEMHRI 446
+ S+ ++ L+Q+ +K + ++ QEW EK + E
Sbjct: 275 QSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKI--------QEWEEK----IQEQEEK 322
Query: 447 KRIESENLRIQNEQKKAAKREEALASFEAWKAMKEKEAKKIAAKKRLEEKNKK-KTEEEN 505
R + E +R EQ++ +R+E + M EKE K ++ + EK +K + +EE
Sbjct: 323 IREQEEKIR---EQEEKMRRQEEM--------MWEKEEKMRRQEEMMWEKEEKMRRQEEM 371
Query: 506 AARKGEALQAFEK--W-KEKKMEYLKEK-NRKEREYERAKKQKEEETVAEKKKDNLTAVE 561
K E ++ E+ W KE+K+ L+EK + +E+ E+ +K++EEE + E++K +
Sbjct: 372 MWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAK 431
Query: 562 KWNEKKEAFFKQKEKEKINEKRKEELKRAEKKDKDKQAINEYEKWLENKE---------K 612
W ++++ ++++EKI E+ K ++ R E+K +++ I E EK E +E +
Sbjct: 432 MWRQEEKI---REQEEKIREQEK-KMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIHE 487
Query: 613 QERIERKQKKRH 624
QE I R+++K H
Sbjct: 488 QEEIWRQKEKMH 499
Score = 72.0 bits (175), Expect = 2e-12
Identities = 62/253 (24%), Positives = 135/253 (53%), Gaps = 32/253 (12%)
Query: 407 DQKPSQKQSIEPDRADNIRAAVYQEWLEKKNVY-----LHEMHRI-----KRIESENLRI 456
++K +++ + ++ + +R W +++ + +HE +I KR E E +R
Sbjct: 362 EEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIRE 421
Query: 457 QNEQK----KAAKREEALASFEAWKAMKEK----EAKKIAAKKRLEEKNKKKTEEENAAR 508
Q +++ K ++EE + E +EK + +KI ++++ E+ K++ +EE +
Sbjct: 422 QEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQ 481
Query: 509 KGEALQAFEKWKEK-KMEYLKEKNRKEREY---ERAKKQKEEETVAEKKKDNLTAVEKWN 564
+ + + E W++K KM +EK RK+ E + K +++EE + E+++ EK
Sbjct: 482 EEKIHEQEEIWRQKEKMHEQEEKIRKQEEKVWRQEEKIREQEEKIREQEEKMWRQEEKIR 541
Query: 565 EKKEAFFKQKEKEKINEKRK--EELKRAEKKDK---DKQAINEYEK--WLENKEKQERIE 617
E++E + +E+EK++E+ K EE KR E++DK ++ I E E+ W + ++ +E+ E
Sbjct: 542 EQEEMW---REEEKMHEQEKIWEEEKRQEQEDKMWRQEEKIREQEEKVWRQEEKIREQEE 598
Query: 618 RKQKKRHSFLESE 630
++Q++ + E
Sbjct: 599 KRQEQEEKMWKQE 611
Score = 68.9 bits (167), Expect = 1e-11
Identities = 74/385 (19%), Positives = 170/385 (44%), Gaps = 45/385 (11%)
Query: 278 NSLKSDENKENSFSADHVTTAVEKSK-ESQVTADDLEEEKAKAELIMDDDRT---VDPLL 333
N++ +E KE + VE K E Q+ +L+ + +A+L++ + D L
Sbjct: 212 NTITDEELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLG 271
Query: 334 SKSQSILISTSATASSKKTIEDRNIKNKKSTNNRASSASARLMTSEFLKKSSSKRRTPST 393
+ QS+ +A + +E+ + N+ + E+ +K +
Sbjct: 272 KELQSV------SAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIRE 325
Query: 394 TTSSHYLGTLKVLDQKPSQKQSIEPDRADNIRAAVYQEWLEKKNVYLHEMHRIKRIESEN 453
++ ++K +++ + ++ + +R W +K + + + E
Sbjct: 326 QEEK-----IREQEEKMRRQEEMMWEKEEKMRRQEEMMW--EKEEKMRRQEEMMWEKEEK 378
Query: 454 LRIQNE-----QKKAAKREEALASFEAWKAMKEK---EAKKIAAKKRLEEKNKKKTEEEN 505
+R Q E ++K + EE + E + +EK E K +KR E++ K +EE
Sbjct: 379 MRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEK 438
Query: 506 AARKGEALQAFEK--WKEKKMEYLKEKNRKEREYERAKKQKEEETVAEKKKDNLTAVEKW 563
+ E ++ EK W++++ + +EK R+E + + ++ +E ++++ EK
Sbjct: 439 IREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIHEQEEIWRQKEKM 498
Query: 564 NEKKEAFFKQKEK------------EKINE------KRKEELKRAEKKDKDKQAINEYEK 605
+E++E KQ+EK EKI E +++E+++ E+ ++++ ++E EK
Sbjct: 499 HEQEEKIRKQEEKVWRQEEKIREQEEKIREQEEKMWRQEEKIREQEEMWREEEKMHEQEK 558
Query: 606 WLENKEKQERIERKQKKRHSFLESE 630
E +++QE+ ++ ++ E E
Sbjct: 559 IWEEEKRQEQEDKMWRQEEKIREQE 583
Score = 67.8 bits (164), Expect = 3e-11
Identities = 48/212 (22%), Positives = 114/212 (53%), Gaps = 10/212 (4%)
Query: 419 DRADNIRAAVYQEWLEKKNVY-LHEMHRIKRIESENLRIQNEQKKAAKREEALASFEAWK 477
++ + IR + W +++ + EM R + E +I E+K+ + ++ E +
Sbjct: 521 EQEEKIREQEEKMWRQEEKIREQEEMWREEEKMHEQEKIWEEEKRQEQEDKMWRQEEKIR 580
Query: 478 AMKEKEAKKIAAKKRLEEKNKKKTEEENAARKGEALQAFEKWKEKKMEYLKEKNRKEREY 537
+EK ++ +K E++ K++ +EE ++ E ++ E+ +++ E ++E+ K RE
Sbjct: 581 EQEEKVWRQ--EEKIREQEEKRQEQEEKMWKQEEKIREQEEKIQEQEEKIREQEEKIREQ 638
Query: 538 ERAKKQKEEETVAEKKKDNLTAVEKWNEKKEAFFKQKEKEKINEKR----KEELKRAEK- 592
E Q++EE + E+++ EK E++E ++Q+EK + EK+ +E+++ E+
Sbjct: 639 EEMT-QEQEEKMGEQEEKMCEQEEKMQEQEETMWRQEEKIREQEKKIREQEEKIREQEEM 697
Query: 593 -KDKDKQAINEYEKWLENKEKQERIERKQKKR 623
++++++ + EK E +EK + E K +++
Sbjct: 698 MQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQ 729
Score = 65.1 bits (157), Expect = 2e-10
Identities = 58/254 (22%), Positives = 122/254 (48%), Gaps = 22/254 (8%)
Query: 404 KVLDQKPSQKQSIEP--------DRADNIRAAVYQEWLEKKNVYLHEMHRIKRIESENLR 455
K+ +Q+ Q+Q + ++ + IR + W +++ ++ E R + E
Sbjct: 418 KIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEE 477
Query: 456 IQNEQKKAAKREEALASFEAWKAMKEKEAKKIAAKKRLEEKNKKKTE-----EENAARKG 510
+ +++K ++EE E +EK K+ R EEK +++ E EE R+
Sbjct: 478 MWRQEEKIHEQEEIWRQKEKMHEQEEKIRKQEEKVWRQEEKIREQEEKIREQEEKMWRQE 537
Query: 511 EALQAFEK-WKEKKMEYLKEK--NRKEREYERAKKQKEEETVAEKKKDNLTAVEKWNEKK 567
E ++ E+ W+E++ + +EK ++R+ + K ++EE + E+++ EK E++
Sbjct: 538 EKIREQEEMWREEEKMHEQEKIWEEEKRQEQEDKMWRQEEKIREQEEKVWRQEEKIREQE 597
Query: 568 EAFFKQKEK-----EKINEKRKEELKRAEKKDKDKQAINEYEKWL-ENKEKQERIERKQK 621
E +Q+EK EKI E+ ++ ++ EK + ++ I E E+ E +EK E K
Sbjct: 598 EKRQEQEEKMWKQEEKIREQEEKIQEQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMC 657
Query: 622 KRHSFLESEALPPW 635
++ ++ + W
Sbjct: 658 EQEEKMQEQEETMW 671
Score = 63.9 bits (154), Expect = 4e-10
Identities = 63/247 (25%), Positives = 125/247 (50%), Gaps = 39/247 (15%)
Query: 425 RAAVYQEWLEKKNVYLHEMHRIKRIESENLRIQ---NEQKKAAKREEALASFEAWKAMKE 481
R + E L++KN L E +++ +ESE IQ E K+ +R + L + +A +
Sbjct: 211 RNTITDEELKEKNAKLQE--KLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEAD 268
Query: 482 ---KEAKKIAAKKRLE-EKNK-----KKTEEENAARKGEALQAFEKW---KEKKMEYLKE 529
KE + ++AK + + E+N+ + +EE R+ E +Q +E+ +E+K+ +E
Sbjct: 269 HLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEE 328
Query: 530 KNRKERE---------YERAKKQKEEETVAEKKKDNLTAVEK--WNEKKEAFFKQKE--- 575
K R++ E +E+ +K + +E + +K++ + E+ W EK+E +Q+E
Sbjct: 329 KIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMW-EKEEKMRRQEEMMW 387
Query: 576 --KEKINE-----KRKEELKRAEKKDKDKQAINEYEKWLENKEKQERIERKQKKRHSFLE 628
+EKI E +E+++ E+K ++++ I E EK E + K R E K +++ +
Sbjct: 388 EKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIR 447
Query: 629 SEALPPW 635
+ W
Sbjct: 448 EQEKKMW 454
Score = 59.3 bits (142), Expect = 1e-08
Identities = 52/251 (20%), Positives = 118/251 (47%), Gaps = 27/251 (10%)
Query: 412 QKQSIEPDRADNIRAAVYQEWLEKKNVYLHEMHRIKRIESENLRIQNEQKKAAKREEALA 471
QK+ + ++ + IR + W +++ + E ++I + ++ +++K ++EE
Sbjct: 494 QKEKMH-EQEEKIRKQEEKVWRQEEKIREQE----EKIREQEEKMWRQEEKIREQEEMWR 548
Query: 472 SFEAWKAMK---EKEAKKIAAKKRLEEKNKKKTEEENAARKGEALQAFEKWKEKKMEYLK 528
E + E+E ++ K ++ K + +EE R+ E ++ E+ ++++ E +
Sbjct: 549 EEEKMHEQEKIWEEEKRQEQEDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQEEKMW 608
Query: 529 EKNRKEREYERAKKQKEE------ETVAEKKKDNLTAVEKWNEKKEAFFKQKEK------ 576
++ K RE E +++EE E + E+++ EK E++E +Q+EK
Sbjct: 609 KQEEKIREQEEKIQEQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEE 668
Query: 577 ------EKINEKRKEELKRAEK-KDKDKQAINEYEKWLENKEKQERIERKQKKRHSFLES 629
EKI E+ K+ ++ EK +++++ + EK E +EK E K +++ +
Sbjct: 669 TMWRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRR 728
Query: 630 EALPPWSPPSR 640
+ W R
Sbjct: 729 QEEKMWEQEVR 739
Score = 56.6 bits (135), Expect = 7e-08
Identities = 43/206 (20%), Positives = 113/206 (54%), Gaps = 29/206 (14%)
Query: 432 WLEKKNVYLHEMHRIKRIESENLRIQNEQKKAAKREEALASFEA--WKAMKE-------- 481
W +K+ ++ E ++I + ++ +++K ++EE + E W+ ++
Sbjct: 492 WRQKEKMHEQE----EKIRKQEEKVWRQEEKIREQEEKIREQEEKMWRQEEKIREQEEMW 547
Query: 482 KEAKKIAAKKRLEEKNKKKTEEENAARKGEALQAFEKWKEKKMEYLKEKNRKEREYERAK 541
+E +K+ ++++ E+ K++ +E+ R+ E ++ +E+K+ +EK R++ E K
Sbjct: 548 REEEKMHEQEKIWEEEKRQEQEDKMWRQEEKIRE----QEEKVWRQEEKIREQEE----K 599
Query: 542 KQKEEETVAEKKKDNLTAVEKWNEKKEAFFKQKEKEKINEKRKEELKRAEKKDKDKQAIN 601
+Q++EE + ++++ EK E++E ++++EKI E+ + ++ EK + ++ +
Sbjct: 600 RQEQEEKMWKQEEKIREQEEKIQEQEEKI--REQEEKIREQEEMTQEQEEKMGEQEEKMC 657
Query: 602 EYEKWLENKE-----KQERIERKQKK 622
E E+ ++ +E ++E+I ++KK
Sbjct: 658 EQEEKMQEQEETMWRQEEKIREQEKK 683
>gi|239745079 PREDICTED: Putative golgin subfamily A member 6-like
protein 6 [Homo sapiens]
Length = 724
Score = 72.8 bits (177), Expect = 9e-13
Identities = 88/367 (23%), Positives = 165/367 (44%), Gaps = 50/367 (13%)
Query: 273 ITENHNSLKSDENKENSFSADHVTTAVEKSKESQVTADDLEEEKAKAELIMDDDRTVDPL 332
I+ H+S K E + SA A +K K + ++L +E+ L + + D
Sbjct: 225 ISRLHDSWKFAGELEQALSA----VATQKKKADRYI-EELTKERDALSLELYRNTITDEE 279
Query: 333 LSKSQSILISTSATASSKKTIEDRNIKNKKSTNNRASSASARLMTSEFLKKSSSKRRTPS 392
L + + L S+K+ N+K K RA L+ + L+ +
Sbjct: 280 LKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKL----LLPQQQLQAEADHLGKEL 335
Query: 393 TTTSSHYLGTLKV------LDQKPSQKQSIEPDRADNIRAAVYQEWLEKKNVYLHEMHRI 446
+ S+ ++ L+Q+ +K + ++ QEW EK + E
Sbjct: 336 QSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKI--------QEWEEK----IQEQEEK 383
Query: 447 KRIESENLRIQNEQKKAAK-----REEALASFEAWKAMKEKEAKKIAAKKRLEEKNKKKT 501
R + E +R Q E+ + + +EE + E + M EKE K ++ + EK +K
Sbjct: 384 IREQEEKIREQEEKMRRQEEMMWEKEEKMRRQE--EMMWEKEEKMRRQEEMMWEKEEKIR 441
Query: 502 EEENAARKGEALQAFEKWKEKKMEYLKEKNRKEREYERAKKQKEEETVAEKKKDNLTAVE 561
E E + E ++ E EK+ E K + +++R+ + AK ++EE + E++ E
Sbjct: 442 ELEEKMHEQEKIREQE---EKRQEEEKIREQEKRQEQEAKMWRQEEKIREQE-------E 491
Query: 562 KWNEKKEAFFKQKEKEKINEKRKEELKRAEKKD--KDKQAINEYEKWLENKEK----QER 615
K E++E ++Q+EK EK +EE KR E+++ + ++ I E E+ KEK +E+
Sbjct: 492 KIREQEEKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKIHEQEEK 551
Query: 616 IERKQKK 622
I ++++K
Sbjct: 552 IRKQEEK 558
Score = 68.9 bits (167), Expect = 1e-11
Identities = 76/384 (19%), Positives = 169/384 (44%), Gaps = 34/384 (8%)
Query: 278 NSLKSDENKENSFSADHVTTAVEKSK-ESQVTADDLEEEKAKAELIMDDDRT---VDPLL 333
N++ +E KE + VE K E Q+ +L+ + +A+L++ + D L
Sbjct: 273 NTITDEELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLG 332
Query: 334 SKSQSILISTSATASSKKTIEDRNIKNKKST---NNRASSASARLMTSEFLKKSSSKRRT 390
+ QS+ A + N + ++ + ++ E + ++
Sbjct: 333 KELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIR 392
Query: 391 PSTTTSSHYLGTLKVLDQKPSQKQSIEPDRADNIRAAVYQEWLEKKNVY-----LHEMHR 445
+ ++K +++ + ++ + +R W +++ + +HE +
Sbjct: 393 EQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEK 452
Query: 446 I-----KRIESENLRIQNEQK----KAAKREEALASFEAWKAMKEKEAK------KIAAK 490
I KR E E +R Q +++ K ++EE + E + ++E+E K KI +
Sbjct: 453 IREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQE--EKIREQEEKMWRQEEKIHEQ 510
Query: 491 KRLEEKNKKKTEEENAARKGEALQAFEKWKEK-KMEYLKEKNRKERE---YERAKKQKEE 546
+++ E+ K++ +EE ++ + + E W++K K+ +EK RK+ E + K +E
Sbjct: 511 EKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKIHEQEEKIRKQEEKMWRQEEKMHDQE 570
Query: 547 ETVAEKKKDNLTAVEKWNEKKEAFFKQKEKEKINEKRKEELKRAEKKDKDKQAINEYEKW 606
E + E+++ EK E++E +Q+EK + E+ +E + + ++K E EK
Sbjct: 571 EKIREQEEKVWRQEEKIREQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQE-EKM 629
Query: 607 LENKEKQERIERKQKKRHSFLESE 630
E +EK R E K +++ + +
Sbjct: 630 QEQEEKMRRQEEKIREQEKKIREQ 653
Score = 66.6 bits (161), Expect = 7e-11
Identities = 77/344 (22%), Positives = 160/344 (46%), Gaps = 40/344 (11%)
Query: 299 VEKSKESQVTADDLEEE-KAKAELIMDDDRTVDPLLSKSQSILISTSATASSKKTIEDRN 357
+ + +S A +LE+ A A DR ++ L + ++ + + + ++++N
Sbjct: 225 ISRLHDSWKFAGELEQALSAVATQKKKADRYIEELTKERDALSLELYRNTITDEELKEKN 284
Query: 358 IKNKKSTNNRASSASARLMTSEFLKKSSSKRRTPSTTTSSHYLGTLKVLDQKPSQKQSIE 417
K ++ S S + + LK+ + + +L Q+ Q ++
Sbjct: 285 AKLQEKLQLVESEKSEIQLNVKELKRKLERAKL--------------LLPQQQLQAEADH 330
Query: 418 PDRADNIRAAVYQEWLEKKNVY--LHEMHRIKRIESENLRIQNEQKKAAKREEALASFEA 475
+ +A Q +E+ ++ L++ K E +IQ ++K ++EE + E
Sbjct: 331 LGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEE-KIQEWEEKIQEQEEKIREQE- 388
Query: 476 WKAMKEKEAKKIAAKKRLEEKNKK-KTEEENAARKGEALQAFEKWKEKKMEYLKEKNRKE 534
+ ++E+E K ++ + EK +K + +EE K E ++ E+ +K E ++E K
Sbjct: 389 -EKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKM 447
Query: 535 REYERAKKQKEEETVAEKKKDNLTAVEKWNEKKEAFFKQKEK-----EKINEKRKEELKR 589
E E+ ++Q+E+ EK ++ EK E++ ++Q+EK EKI E ++E++ R
Sbjct: 448 HEQEKIREQEEKRQEEEKIREQ----EKRQEQEAKMWRQEEKIREQEEKIRE-QEEKMWR 502
Query: 590 AEKKDKDKQAINEYEKWLENKE---------KQERIERKQKKRH 624
E+K +++ I E EK E +E +QE I R+++K H
Sbjct: 503 QEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKIH 546
Score = 65.5 bits (158), Expect = 1e-10
Identities = 51/234 (21%), Positives = 115/234 (49%), Gaps = 17/234 (7%)
Query: 404 KVLDQKPSQKQSIEP--------DRADNIRAAVYQEWLEKKNVYLHEMHRIKRIESENLR 455
K+ +Q+ Q+Q + ++ + IR + W +++ ++ E R + E
Sbjct: 465 KIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEKMWRQEEKIHEQEKIREEEKRQEQEE 524
Query: 456 IQNEQKKAAKREEALASFEAWKAMKEKEAKKIAAKKRLEEKNKKKTEEENAARKGEALQA 515
+ +++K ++EE E +EK K+ +K ++ K +EE + E +
Sbjct: 525 MWRQEEKIREQEEIWRQKEKIHEQEEKIRKQ--EEKMWRQEEKMHDQEEKIREQEEKVWR 582
Query: 516 FEKWKEKKMEYLKEKNRKEREYERAKKQKEEETVAEKKKDNLTAVEKWNEKKEAFFKQKE 575
E+ ++ E ++E+ K RE E Q++EE + E+++ EK E++E +Q+E
Sbjct: 583 QEEKIREQEEKIREQEEKIREQEEMT-QEQEEKMGEQEEKMCEQEEKMQEQEEKMRRQEE 641
Query: 576 KEKINEKR----KEELKRAEK--KDKDKQAINEYEKWLENKEKQERIERKQKKR 623
K + EK+ +E+++ E+ ++++++ + EK E +EK + E K +++
Sbjct: 642 KIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQ 695
Score = 61.2 bits (147), Expect = 3e-09
Identities = 49/217 (22%), Positives = 116/217 (53%), Gaps = 9/217 (4%)
Query: 417 EPDRADNIRAAVYQEWLEKKNVYLHE--MHRIKRIESENLRIQNEQKKAAKREEALASFE 474
E R + R + W +++ + E + ++I + +I+ +++K ++EE + E
Sbjct: 511 EKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKIHEQEEKIRKQEEKMWRQEEKMHDQE 570
Query: 475 AWKAMKEKEAKKIAAKKRLEEKNKKKTEEENAARKGEAL-QAFEKWKEKKMEYLKEKNRK 533
+ ++E+E K ++++ E+ +K E+E R+ E + Q E+ ++ E + E+ K
Sbjct: 571 --EKIREQEEKVWRQEEKIREQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEK 628
Query: 534 EREYERAKKQKEEETVAEKKKDNLTAVEKWNEKKEAFFKQKEKEKINEKRKEELKRAEK- 592
+E E K +++EE + E++K EK E++E Q+++EK+ E+ ++ ++ EK
Sbjct: 629 MQEQEE-KMRRQEEKIREQEKKIREQEEKIREQEE--MMQEQEEKMWEQEEKMCEQEEKM 685
Query: 593 KDKDKQAINEYEKWLENKEKQERIERKQKKRHSFLES 629
++++++ + EK E + + + E K ++ LE+
Sbjct: 686 QEQEEKMRRQEEKMWEQEVRLRQQEEKMQEHQEHLEA 722
Score = 58.9 bits (141), Expect = 1e-08
Identities = 55/238 (23%), Positives = 118/238 (49%), Gaps = 25/238 (10%)
Query: 404 KVLDQKPSQKQSIEPDRADNIRAAVYQEWLEKKNVYLHEMHRIKRIESENLRIQ---NEQ 460
K+ +Q+ +++ + + + + W +++ + E +I+ E + R + +EQ
Sbjct: 452 KIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQE-EKIREQEEKMWRQEEKIHEQ 510
Query: 461 KKAAKREEALASFEAWKAMKEKEAKKIAAKKRLEEKNKKKTEEENAARKGEALQAFEKWK 520
+K + E+ E W+ + +KI ++ + + +K E+E RK E + W+
Sbjct: 511 EKIREEEKRQEQEEMWR-----QEEKIREQEEIWRQKEKIHEQEEKIRKQEE----KMWR 561
Query: 521 -EKKMEYLKEKNRKEREYERAKKQKEEETVAEKKKDNLTAVEKWNEKKEAFFKQKEK--- 576
E+KM +EK R++ E K ++EE + E+++ EK E++E +Q+EK
Sbjct: 562 QEEKMHDQEEKIREQEE----KVWRQEEKIREQEEKIREQEEKIREQEEMTQEQEEKMGE 617
Query: 577 --EKINEKRKEELKRAEKKDKDKQAINEYEKWLENKEK--QERIERKQKKRHSFLESE 630
EK+ E+ ++ ++ EK + ++ I E EK + +E+ +E+ E Q++ E E
Sbjct: 618 QEEKMCEQEEKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQE 675
Score = 58.5 bits (140), Expect = 2e-08
Identities = 57/235 (24%), Positives = 112/235 (47%), Gaps = 29/235 (12%)
Query: 425 RAAVYQEWLEKKNVYLHEMHRIKRIESENLRIQ---NEQKKAAKREEALASFEAWKAMKE 481
R + E L++KN L E +++ +ESE IQ E K+ +R + L + +A +
Sbjct: 272 RNTITDEELKEKNAKLQE--KLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEAD 329
Query: 482 KEAKKIAAKKRLEEKNKKKTEEENAARKGEALQAFEKWK-EKKMEYLKEKNRKEREYERA 540
K++ + + K + + EE + Q + W+ E+K++ +EK +++ E R
Sbjct: 330 HLGKELQS---VSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIRE 386
Query: 541 KKQK----------EEETVAEKKKDNLTAVEKWNEKKEAFFKQKE-----KEKINE---- 581
+++K +EE + EK++ E EK+E +Q+E +EKI E
Sbjct: 387 QEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEK 446
Query: 582 -KRKEELKRAEKKDKDKQAINEYEKWLENKEKQERIERKQKKRHSFLESEALPPW 635
+E+++ E+K ++++ I E EK E + K R E K +++ + + W
Sbjct: 447 MHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEKMW 501
Score = 55.8 bits (133), Expect = 1e-07
Identities = 44/199 (22%), Positives = 110/199 (55%), Gaps = 20/199 (10%)
Query: 412 QKQSIEPDRADNIRAAVYQEWLEKKNVYLHEMHRIKRIESENLRIQNEQKKAAKREEALA 471
QK+ I ++ + IR + W +++ ++ E ++I + ++ +++K ++EE +
Sbjct: 541 QKEKIH-EQEEKIRKQEEKMWRQEEKMHDQE----EKIREQEEKVWRQEEKIREQEEKIR 595
Query: 472 SFEAWKAMKEKEAKKIAAKKRLEEKNKKKTEEENAARKGEALQAFEKWKEKKMEYLKEKN 531
E + ++E+E ++++ E+ +K E+E E +Q E+ ++ E ++E+
Sbjct: 596 EQE--EKIREQEEMTQEQEEKMGEQEEKMCEQE------EKMQEQEEKMRRQEEKIREQE 647
Query: 532 RKEREYERAKKQKEEETVAEKKKDNLTAVEKWNEKKEAFFKQKEKEKINEKR--KEELKR 589
+K RE E K +++EE + E+++ EK E++E +Q+EK + E++ ++E++
Sbjct: 648 KKIREQEE-KIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRL 706
Query: 590 AEKKDKDKQAINEYEKWLE 608
++++K + E+++ LE
Sbjct: 707 RQQEEK----MQEHQEHLE 721
>gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens]
Length = 1020
Score = 71.2 bits (173), Expect = 3e-12
Identities = 135/591 (22%), Positives = 231/591 (39%), Gaps = 83/591 (14%)
Query: 83 EKNPSKLLFLKTNKSNGNITKD---EPVCAIKNEEEMAPDGCEDIVVKSFSESQNKDEEF 139
EK+ + + ++ +T++ E K EE +G E+ + E + K
Sbjct: 448 EKSEKETVIVEEQTEETQVTEEVTEEEEKEAKEEEGKEEEGGEEEEAEG-GEEETKSPPA 506
Query: 140 EKDKIKMKPKPRILSIKSTSSAENNSLDTDDHFKPSPRPRSMLKKKSHMEEKDGLEDKET 199
E+ K + ++ S AE S + ++ P+ +S K KS +E+ +
Sbjct: 507 EEAASPEKEAKSPVKEEAKSPAEAKSPEKEEAKSPA-EVKSPEKAKSPAKEE--AKSPPE 563
Query: 200 ALSEELELHSAPSSLPTPNGIQLEAEKKAFSENLDPEDSCLTSLASSSLKQIL---GDSF 256
A S E E +P+ + +P + A+++A S P ++ A S +K+ ++
Sbjct: 564 AKSPEKEEAKSPAEVKSPEKAKSPAKEEAKS----PAEAKSPEKAKSPVKEEAKSPAEAK 619
Query: 257 SPGSEGNAS---------GKDPNEEITENHNSLKSDENKE--NSFSADHVTTAVEKSKE- 304
SP E S K P +E ++ KS E +E + A A KS E
Sbjct: 620 SPVKEEAKSPAEVKSPEKAKSPTKEEAKSPEKAKSPEKEEAKSPEKAKSPVKAEAKSPEK 679
Query: 305 --SQVTADDLEEEKAKA---ELIMDDDRTVDPLLSKSQSILISTSATASSKKTIEDRNIK 359
S V A+ EKAK+ E ++ P+ +++S + S KT E
Sbjct: 680 AKSPVKAEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKTPEKAKSP 739
Query: 360 NKKSTNNRASSASARLMTSEFLKKSSSKRRTPSTTTSSHYLGTLKVLDQKPSQKQSIEPD 419
K+ + + S ++ L S + +TP+ + + P +++ P+
Sbjct: 740 VKEEAKSPEKAKSPE--KAKTLDVKSPEAKTPAKEEARSPADKFPEKAKSPVKEEVKSPE 797
Query: 420 RA------------------DNIRAAVYQEWLEKKNVYLHEMHRIKRIESENLRIQNEQK 461
+A + +++ V +E + + V + E + E + E+K
Sbjct: 798 KAKSPLKEDAKAPEKEIPKKEEVKSPVKEEE-KPQEVKVKEPPKKAEEEKAPATPKTEEK 856
Query: 462 KAAKREEALASFEAWKAM----------KEKEAKKIAAKKRLEEKNKKKTEEENAARKGE 511
K +K+EEA EA K K KE+K A K+ E+K K T E+ A K E
Sbjct: 857 KDSKKEEAPKK-EAPKPKVEEKKEPAVEKPKESKVEAKKEEAEDKKKVPTPEKEAPAKVE 915
Query: 512 ALQAFEKWKEKKMEYLKEKNRKEREYERAKKQKEEETVAEKKKDNLTAVEKWNEKKEAFF 571
K+ KEK ++ K KE AEKK+ A EK + K+E
Sbjct: 916 V---------KEDAKPKEKTEVAKKEPDDAKAKEPSKPAEKKE---AAPEKKDTKEEKAK 963
Query: 572 KQKEKEKINEKRKEELKRAEKKDKDKQAINEYEKWLENKEKQERIERKQKK 622
K +EK K K KE+ K K+ +A E EK ++K K
Sbjct: 964 KPEEKPKTEAKAKEDDKTLSKEPSKPKA--------EKAEKSSSTDQKDSK 1006
Score = 58.9 bits (141), Expect = 1e-08
Identities = 104/500 (20%), Positives = 199/500 (39%), Gaps = 37/500 (7%)
Query: 143 KIKMKPKPRIL--SIKSTSSAENNSLDTDDHFKPSPRPRSMLKKKSHMEEKDGLEDKETA 200
K+K + K +++ S K T E + +T + + K++ EE+ G E++
Sbjct: 437 KVKSEEKIKVVEKSEKETVIVEEQTEETQVTEEVTEEEEKEAKEEEGKEEEGGEEEEAEG 496
Query: 201 LSEELELHSAPSSLPTPNGIQ--LEAEKKAFSENLDPEDSCLTSLASSSLKQILGDSFSP 258
EE + A + + ++ E K+ +E PE S A +
Sbjct: 497 GEEETKSPPAEEAASPEKEAKSPVKEEAKSPAEAKSPEKEEAKSPAEVKSPEKAKSPAKE 556
Query: 259 GSEGNASGKDPNEEITENHNSLKSDENKENSFSADHVTTAVEKSKESQVTADDLEEEKAK 318
++ K P +E ++ +KS E ++ + + A KS E + + EE K+
Sbjct: 557 EAKSPPEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPAEAKSPE-KAKSPVKEEAKSP 615
Query: 319 AELIMDDDRTVDPLLSKSQSILISTSATASSKKTIEDRNIKNKKSTNNRASSASARLMTS 378
AE P+ +++S S + T E+ K + + + S S
Sbjct: 616 AE-------AKSPVKEEAKSPAEVKSPEKAKSPTKEEAKSPEKAKSPEKEEAKSPEKAKS 668
Query: 379 EFLKKSSSKRRTPSTTTSSHYLGTLKVLDQKPSQKQSIEPDRADNIRAAVYQEWLEKKNV 438
++ S + S + + P ++++ P++A ++ V +E +
Sbjct: 669 PVKAEAKSPEKAKSPVKAE---AKSPEKAKSPVKEEAKSPEKA---KSPVKEEAKSPEKA 722
Query: 439 YLHEMHRIKRIESENLRIQNEQK---KAAKREEA----LASFEAWKAMKEKEAKKIAAKK 491
K E ++ E K KA E+A + S EA KE EA+ A K
Sbjct: 723 KSPVKEEAKTPEKAKSPVKEEAKSPEKAKSPEKAKTLDVKSPEAKTPAKE-EARSPADKF 781
Query: 492 RLEEKNKKKTEEENAARKGEALQAFEKWKEKKMEYLKEKNRKEREYERAKKQKEEETVAE 551
+ K+ K E ++ + L+ K EK++ +E +E E+ ++ K +E +
Sbjct: 782 PEKAKSPVKEEVKSPEKAKSPLKEDAKAPEKEIPKKEEVKSPVKEEEKPQEVKVKEPPKK 841
Query: 552 KKKDNLTAVEKWNEKKEAFFKQKEKEKINEKRKEELKRAEKKDKDKQAINEYEKWLENKE 611
+++ A K EKK++ +KE+ +K + K EKK+ EK E+K
Sbjct: 842 AEEEKAPATPKTEEKKDS-----KKEEAPKKEAPKPKVEEKKEP------AVEKPKESKV 890
Query: 612 KQERIERKQKKRHSFLESEA 631
+ ++ E + KK+ E EA
Sbjct: 891 EAKKEEAEDKKKVPTPEKEA 910
Score = 58.5 bits (140), Expect = 2e-08
Identities = 115/601 (19%), Positives = 217/601 (36%), Gaps = 58/601 (9%)
Query: 13 TKSPKVTKRTTFQDELIRAITARSARQRSSEYSDDFDSDEIVSLGDFSDTSADENSVNKK 72
T+ +VT+ T ++E A + E + +E + ++ E
Sbjct: 461 TEETQVTEEVTEEEEK-EAKEEEGKEEEGGEEEEAEGGEEETKSPPAEEAASPEKEAKSP 519
Query: 73 MNDFHISDDEEKNPSKLLFLKTNKSNGNITKDEPVCAIKNEEEMAPDGCEDIVVKSFSES 132
+ + S E K+P K + KS + E + EE +P + E+
Sbjct: 520 VKEEAKSPAEAKSPEK----EEAKSPAEVKSPEKAKSPAKEEAKSPPEAKS---PEKEEA 572
Query: 133 QNKDEEFEKDKIKMKPKPRILSIKSTSSAENNSLDTDDHFKPSPRPRSMLKKKSHMEEKD 192
++ E +K K K S S E + K +S +K+++ +
Sbjct: 573 KSPAEVKSPEKAKSPAKEEAKSPAEAKSPEKAKSPVKEEAKSPAEAKSPVKEEAKSPAE- 631
Query: 193 GLEDKETALSEELELHSAPSSLPTPNGIQLEAEKKAFS----ENLDPEDSCLTSLASSSL 248
++ E A S E +P +P + ++ +KA S E PE + A +
Sbjct: 632 -VKSPEKAKSPTKEEAKSPEKAKSPEKEEAKSPEKAKSPVKAEAKSPEKAKSPVKAEAKS 690
Query: 249 KQILGDSFSPGSEGNASGKDPNEEITENHNSLKSDENKENSFSADHVTTAVEKSKESQVT 308
+ ++ K P +E ++ KS KE + + + + V++ +S
Sbjct: 691 PEKAKSPVKEEAKSPEKAKSPVKEEAKSPEKAKSPV-KEEAKTPEKAKSPVKEEAKSPEK 749
Query: 309 ADDLEEEKAKAELIMDDDRTVDPLLSKSQSILISTSATASSKKTIEDRNIKNKKSTNNRA 368
A E+ K L + P +++S A S E ++ + KS
Sbjct: 750 AKSPEKAKT---LDVKSPEAKTPAKEEARSPADKFPEKAKSPVKEEVKSPEKAKSPLKED 806
Query: 369 SSASARLMTSEFLKKSSSK----------RRTPSTTTSSHYLGTLKVLDQKPSQKQSIEP 418
+ A + + + KS K + P T K ++K S+K+
Sbjct: 807 AKAPEKEIPKKEEVKSPVKEEEKPQEVKVKEPPKKAEEEKAPATPKTEEKKDSKKEEAPK 866
Query: 419 DRADNIRAAVYQEWLEKKNVYLHEMHRIKRIESENLRIQNEQKKAAKREEALASFEAWKA 478
A + +E+K E + ++E++ ++++K +EA A E +
Sbjct: 867 KEAPKPK-------VEEKKEPAVEKPKESKVEAKKEEAEDKKKVPTPEKEAPAKVEVKED 919
Query: 479 MKEKEAKKIAAKKRLEEKNKKKTEEENAARKGEALQAFEKWKEKKMEYLKEKNRKEREYE 538
K KE ++A K E + K E A K EA + KE+K + +EK + E
Sbjct: 920 AKPKEKTEVAKK---EPDDAKAKEPSKPAEKKEAAPEKKDTKEEKAKKPEEKPKTEA--- 973
Query: 539 RAKKQKEEETVAEKKKDNLTAVEKWNEKKEAFFKQKEKEKINEKRKEELKRAEKKDKDKQ 598
K KE++ K+ K ++ EK + +++ K EK +DK
Sbjct: 974 ---KAKEDDKTLSKEPSKP--------------KAEKAEKSSSTDQKDSKPPEKATEDKA 1016
Query: 599 A 599
A
Sbjct: 1017 A 1017
Score = 55.5 bits (132), Expect = 2e-07
Identities = 91/375 (24%), Positives = 158/375 (42%), Gaps = 33/375 (8%)
Query: 269 PNEEITENHNSLKSDENKENSFSADHVTTAV-EKSKESQVTADDLEEE--KAKAELIMDD 325
P H +KS+E + ++ T V E+++E+QVT + EEE +AK E ++
Sbjct: 427 PKIPSVSTHIKVKSEEKIKVVEKSEKETVIVEEQTEETQVTEEVTEEEEKEAKEEEGKEE 486
Query: 326 DRTVDPLLSKSQSILISTSATASSKKTIEDRN-IKNKKSTNNRASSASARLMTSEFLKKS 384
+ + + S A ++ E ++ +K + + A S S KS
Sbjct: 487 EGGEEEEAEGGEEETKSPPAEEAASPEKEAKSPVKEEAKSPAEAKSPEKEEAKSPAEVKS 546
Query: 385 SSKRRTPSTTTSSHYLGTLKVLDQKPSQKQSIEPDRADNIRAAVYQEWLEKKNVYLHEMH 444
K ++P+ ++ S ++ P++ + A + + K+ E
Sbjct: 547 PEKAKSPAK-------------EEAKSPPEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAK 593
Query: 445 RIKRIESENLRIQNEQKKAAKREEALASFEAWKAMKEKEAKKIAAKKRLEEKNKKKTEEE 504
+S E+ K+ +EEA + EA +KE+ K A+ + EK K T+EE
Sbjct: 594 SPAEAKSP------EKAKSPVKEEAKSPAEAKSPVKEE--AKSPAEVKSPEKAKSPTKEE 645
Query: 505 NAARKGEALQAFEKWKEKKMEYLKEKNRKE-REYERAKKQ-KEEETVAEKKKDNLTAVEK 562
A+ E ++ EK + K E K + E + E+AK K E EK K + K
Sbjct: 646 --AKSPEKAKSPEKEEAKSPEKAKSPVKAEAKSPEKAKSPVKAEAKSPEKAKSPVKEEAK 703
Query: 563 WNEKKEAFFKQKEK--EKINEKRKEELKRAEK-KDKDKQAINEYEKWLENKEKQERIERK 619
EK ++ K++ K EK KEE K EK K K+ EK ++ EK + ++ K
Sbjct: 704 SPEKAKSPVKEEAKSPEKAKSPVKEEAKTPEKAKSPVKEEAKSPEK-AKSPEKAKTLDVK 762
Query: 620 QKKRHSFLESEALPP 634
+ + + EA P
Sbjct: 763 SPEAKTPAKEEARSP 777
Score = 35.4 bits (80), Expect = 0.16
Identities = 53/280 (18%), Positives = 113/280 (40%), Gaps = 10/280 (3%)
Query: 336 SQSILISTSATASSKKTIEDRNIKNKKSTNNRASSASARLMTSEFLKKSSSKRRTPSTTT 395
S++ ++T A S+++ I + ++ R + A T + L++ S+
Sbjct: 301 SEAAKVNTDAMRSAQEEITEY----RRQLQARTTELEALKSTKDSLERQRSELEDRHQAD 356
Query: 396 SSHYLGTLKVLDQKPSQKQSIEPDRADNIRAAVYQEWLEKKNVYLHEMHRIKRI-ESENL 454
+ Y ++ LD ++ ++ + + A +R YQ+ L K E+ +++ E E
Sbjct: 357 IASYQEAIQQLD---AELRNTKWEMAAQLRE--YQDLLNVKMALDIEIAAYRKLLEGEEC 411
Query: 455 RIQNEQKKAAKREEALASFEAWKAMKEKEAKKIAAKKRLEEKNKKKTEEENAARKGEALQ 514
RI + E +K K +KI ++ E++ E+ + E +
Sbjct: 412 RIGFGPIPFSLPEGLPKIPSVSTHIKVKSEEKIKVVEKSEKETVIVEEQTEETQVTEEVT 471
Query: 515 AFEKWKEKKMEYLKEKNRKEREYERAKKQKEEETVAEKKKDNLTAVEKWNEKKEAFFKQK 574
E+ + K+ E +E+ +E E E +++ + E A E+ ++ + K
Sbjct: 472 EEEEKEAKEEEGKEEEGGEEEEAEGGEEETKSPPAEEAASPEKEAKSPVKEEAKSPAEAK 531
Query: 575 EKEKINEKRKEELKRAEKKDKDKQAINEYEKWLENKEKQE 614
EK K E+K EK + + ++ EK+E
Sbjct: 532 SPEKEEAKSPAEVKSPEKAKSPAKEEAKSPPEAKSPEKEE 571
Score = 34.7 bits (78), Expect = 0.28
Identities = 49/187 (26%), Positives = 72/187 (38%), Gaps = 29/187 (15%)
Query: 406 LDQKPSQKQSIEPDRADNIRAAVYQEWLEKKNVYLHEMHRIKRIESENLRIQNEQKKAAK 465
L + PS I+ + I+ E EK+ V + E ++ E + E++K AK
Sbjct: 426 LPKIPSVSTHIKVKSEEKIKVV---EKSEKETVIVEEQTEETQVTEE---VTEEEEKEAK 479
Query: 466 REEALASFEAWKAMKEKEAKKIAAKKRLEEKNKKKTEEENAARKGEALQAFEKWKEKKME 525
EE KE+E + + EE+ K EE A+ + EA ++ + E
Sbjct: 480 EEEG----------KEEEGGEEEEAEGGEEETKSPPAEEAASPEKEAKSPVKEEAKSPAE 529
Query: 526 YLKEKNRKEREYERAKKQKEEETVAEKKKDNLTAVEKWNEKKEAFFKQKEKEKINEKRKE 585
K E E AK E V +K A E+ EA K EK K
Sbjct: 530 ------AKSPEKEEAKSPAE---VKSPEKAKSPAKEEAKSPPEA----KSPEKEEAKSPA 576
Query: 586 ELKRAEK 592
E+K EK
Sbjct: 577 EVKSPEK 583
>gi|84043963 eukaryotic translation initiation factor 5B [Homo
sapiens]
Length = 1220
Score = 71.2 bits (173), Expect = 3e-12
Identities = 118/475 (24%), Positives = 210/475 (44%), Gaps = 46/475 (9%)
Query: 183 KKKSHMEEKDGLEDKETALSEELE-LHSAPSSLPTPNGIQLEAEKKAFSENLDPEDSCLT 241
K KS KD ++ AL+ E+E +A P + + + EKK ++ D ED L
Sbjct: 6 KNKSEDSTKDDID--LDALAAEIEGAGAAKEQEPQKSKGKKKKEKK--KQDFD-EDDILK 60
Query: 242 SLASSSLKQILGDSFSPGSEGNASGKDPNEEITENHNSLKSDENKENSFSADHVTTAVEK 301
L SL + G + ++ EE T K + K+ SF + +K
Sbjct: 61 ELEELSL-EAQGIKADRETVAVKPTENNEEEFTSKDKKKKGQKGKKQSFDDNDSEELEDK 119
Query: 302 SKESQVTADDLEEEKAKAELIM--DDDRTVDPLLSKSQSILISTSATASSKKTIEDRNIK 359
+S+ TA K K E+ DDD + L K++ ++ + ED + K
Sbjct: 120 DSKSKKTA------KPKVEMYSGSDDDDDFNKLPKKAKGKAQKSNKKWDGSEEDEDNSKK 173
Query: 360 NKKSTNNRASSASARLMTSEFL------KKSSSKRRTPSTTTSSHYLGT---LKVLDQKP 410
K+ + +S S + EFL KK+ + P+ + + +K + QK
Sbjct: 174 IKERSRINSSGESGD-ESDEFLQSRKGQKKNQKNKPGPNIESGNEDDDASFKIKTVAQKK 232
Query: 411 SQKQSIEPDRADNIRAAVYQEWLEKKNVYLHEMHRIKRIESENLRIQNEQKKAA------ 464
++K+ E + D +A + ++ EK+ + + + K+ ES+ + + E K+
Sbjct: 233 AEKKERERKKRDEEKAKL-RKLKEKEELETGKKDQSKQKESQR-KFEEETVKSKVTVDTG 290
Query: 465 ---KREEALASFEAWKAMKEKEAKKIAAKKRLEEKNKKKTEEENAARKG--EALQ-AFEK 518
EE + A + E + KK KK+ EK +K+ E++ K +A+Q A K
Sbjct: 291 VIPASEEKAETPTAAEDDNEGDKKKKDKKKKKGEKEEKEKEKKKGPSKATVKAMQEALAK 350
Query: 519 WK-EKKMEYLKEKNRKEREYERAKKQKEEETVAEKKKDNLTAVEKWNEKKEAFFKQKEKE 577
K E++ + +E+ R +R E K+KEEE + ++K++ EK E+KE +KE +
Sbjct: 351 LKEEEERQKREEEERIKRLEELEAKRKEEERLEQEKRERKKQKEK--ERKERL--KKEGK 406
Query: 578 KINEKRKEELKRAEKKDKDKQAINEYEKWLENKEKQERI--ERKQKKRHSFLESE 630
+ + ++E RAE K QA ++ K+ I ++K+KK LES+
Sbjct: 407 LLTKSQREARARAEATLKLLQAQGVEVPSKDSLPKKRPIYEDKKRKKIPQQLESK 461
Score = 68.2 bits (165), Expect = 2e-11
Identities = 96/419 (22%), Positives = 184/419 (43%), Gaps = 31/419 (7%)
Query: 225 EKKAFSENLDPEDSCLTSLASSSLKQILGDSFSPGSEGNASGKDPNEEITENHNSLKSDE 284
++K SE+ +D L +LA+ P K+ ++ + + LK E
Sbjct: 4 KQKNKSEDSTKDDIDLDALAAEIEGAGAAKEQEPQKSKGKKKKEKKKQDFDEDDILKELE 63
Query: 285 N---KENSFSADHVTTAVE--KSKESQVTADDLEEEKAKAELIMDDDRTVDPLLSKSQSI 339
+ AD T AV+ ++ E + T+ D +++ K + DD + L K
Sbjct: 64 ELSLEAQGIKADRETVAVKPTENNEEEFTSKDKKKKGQKGKKQSFDDNDSEELEDKDSKS 123
Query: 340 LISTSATASSKKTIEDRNIKNK--KSTNNRASSASARLMTSEFLKKSSSKRRTPSTTTSS 397
+ +D + NK K +A ++ + SE + +S K + S SS
Sbjct: 124 KKTAKPKVEMYSGSDDDDDFNKLPKKAKGKAQKSNKKWDGSEEDEDNSKKIKERSRINSS 183
Query: 398 HYLG--TLKVLDQKPSQKQSIEPDRADNIRAAVYQEWLEKKNVYLHEMHRIKRIESENLR 455
G + + L + QK++ + NI E N +IK + + +
Sbjct: 184 GESGDESDEFLQSRKGQKKNQKNKPGPNI---------ESGNEDDDASFKIKTVAQK--K 232
Query: 456 IQNEQKKAAKREEALASFEAWKAMKEKEAKKIAAKKRLEEK-NKKKTEEENAARKGEALQ 514
+ ++++ KR+E A + +KEKE + K + ++K +++K EEE K
Sbjct: 233 AEKKERERKKRDEEKAKL---RKLKEKEELETGKKDQSKQKESQRKFEEETVKSKVTVDT 289
Query: 515 AFEKWKEKKMEY---LKEKNRKEREYERAKKQKEEETVAEKKKDNLTAVEKWNEKKEAFF 571
E+K E ++ N +++ + KK+K E+ EK+K + +EA
Sbjct: 290 GVIPASEEKAETPTAAEDDNEGDKKKKDKKKKKGEKEEKEKEKKKGPSKATVKAMQEALA 349
Query: 572 KQKEKEKINEKRKEELKRAEKKDKDKQAINEYEKWLENKEKQERIERKQKKRHSFLESE 630
K KE+E+ +++EE +R K+ ++ +A + E+ LE +EK+ER ++K+K+R L+ E
Sbjct: 350 KLKEEEE--RQKREEEERI-KRLEELEAKRKEEERLE-QEKRERKKQKEKERKERLKKE 404
Score = 65.5 bits (158), Expect = 1e-10
Identities = 103/568 (18%), Positives = 228/568 (40%), Gaps = 66/568 (11%)
Query: 25 QDELIRAITARSARQRSSEYSDDFDSDEIVSLGDFSDTSADENSVNKKMNDFHISDDEE- 83
++E + ++ + DD DS+E+ S + + K+ + SDD++
Sbjct: 88 EEEFTSKDKKKKGQKGKKQSFDDNDSEELED-----KDSKSKKTAKPKVEMYSGSDDDDD 142
Query: 84 --KNPSKLLFLKTNKSNGNITKDEPVCAIKNEEEMAPDGCEDIVVKSFSESQNKDEEF-- 139
K P K K KSN E +E+ + E + S ES ++ +EF
Sbjct: 143 FNKLPKKAKG-KAQKSNKKWDGSE------EDEDNSKKIKERSRINSSGESGDESDEFLQ 195
Query: 140 ----EKDKIKMKPKPRILSIKSTSSAENNSLDTDDHFK-PSPRPRSMLKKKSHMEEKDGL 194
+K K KP P I E+ + D D FK + + KK+ +++D
Sbjct: 196 SRKGQKKNQKNKPGPNI---------ESGNEDDDASFKIKTVAQKKAEKKERERKKRDEE 246
Query: 195 EDKETALSEELELHSAPSSLPTPNGIQLEAEKKAFSENLDPEDSCLTS-LASSSLKQILG 253
+ K L E+ EL + Q E+++K E + + + T + +S K
Sbjct: 247 KAKLRKLKEKEELETGKKD----QSKQKESQRKFEEETVKSKVTVDTGVIPASEEKAETP 302
Query: 254 DSFSPGSEGNASGKDPNEEITENHNSLKSDENKENSFSADHVTTAVEKSKESQVTADDLE 313
+ +EG+ KD ++ E K + + + + A+ K KE + E
Sbjct: 303 TAAEDDNEGDKKKKDKKKKKGEKEEKEKEKKKGPSKATVKAMQEALAKLKEEEERQKREE 362
Query: 314 EEKAKAELIMDDDRTVDPLLSKSQSILISTSATASSKKTIEDRNIKNKKSTNNRA-SSAS 372
EE+ K ++ R + L + + ++ ++ + K RA + A+
Sbjct: 363 EERIKRLEELEAKRKEEERLEQEKRERKKQKEKERKERLKKEGKLLTKSQREARARAEAT 422
Query: 373 ARLMTSEFLK---KSSSKRRTP-----------------STTTSSHYLGTLKVLDQKPSQ 412
+L+ ++ ++ K S ++ P + S ++V++Q +
Sbjct: 423 LKLLQAQGVEVPSKDSLPKKRPIYEDKKRKKIPQQLESKEVSESMELCAAVEVMEQGVPE 482
Query: 413 KQS----IEPDRADNIRAAVYQEWLEKKNVYLHEMHRIKRIESENLRIQNEQKKAAKREE 468
K+ +EP+ ++ A +W + +++E + I+ ++ + EE
Sbjct: 483 KEETPPPVEPEEEEDTEDAGLDDWEA-----MASDEETEKVEGNKVHIEVKENPEEEEEE 537
Query: 469 ALASFEAWKAMKEKEAKKIAAKKRLEEKNKKKTEEENAARKGEALQAFEKWKEKKMEYLK 528
E ++ +E+E + + +E+++K ++E+++ + + + E + + +
Sbjct: 538 EEEEEEDEESEEEEEEEGESEGSEGDEEDEKVSDEKDSGKTLDKKPSKEMSSDSEYDSDD 597
Query: 529 EKNRKEREYERAKKQKEEETVAEKKKDN 556
++ ++ER Y++AK++ E+ + K N
Sbjct: 598 DRTKEERAYDKAKRRIEKRRLEHSKNVN 625
Score = 64.7 bits (156), Expect = 3e-10
Identities = 126/639 (19%), Positives = 240/639 (37%), Gaps = 102/639 (15%)
Query: 46 DDFDSDEIVSLGDFSDTSADEN---SVNKKMNDFHISDDEEKNPSKLLFLKTNKSNGNIT 102
DD D D + + + + + ++ S KK + D +E + K L + ++ G I
Sbjct: 15 DDIDLDALAAEIEGAGAAKEQEPQKSKGKKKKEKKKQDFDEDDILKELEELSLEAQG-IK 73
Query: 103 KDEPVCAIK----NEEEMAPDGCEDIVVK----SFSESQNKDEEFEKDKIKMKPKPRILS 154
D A+K NEEE + K SF ++ +++ E + K K KP++
Sbjct: 74 ADRETVAVKPTENNEEEFTSKDKKKKGQKGKKQSFDDNDSEELEDKDSKSKKTAKPKVEM 133
Query: 155 IKSTSSAENNSLDTDDHFKPSPRPRSMLKKKSHMEEKDGLEDKETALSEELELHSAPSSL 214
+ D DD F P+ +KS+ ++ DG E+ E + E SS
Sbjct: 134 YSGS--------DDDDDFNKLPKKAKGKAQKSN-KKWDGSEEDEDNSKKIKERSRINSS- 183
Query: 215 PTPNGIQLEAEKKAFSENLDPEDSCLTSLASSSLKQILGDSFSPGSEGNASGKDPNEEIT 274
E+ D D L S Q PG + +D +
Sbjct: 184 ---------------GESGDESDEFLQSRKGQKKNQ----KNKPGPNIESGNEDDDASFK 224
Query: 275 ENHNSLKSDENKENSFSA-DHVTTAVEKSKESQ-VTADDLEEEKAKAELIMDDDRTVDPL 332
+ K E KE D + K KE + + ++ K K ++ TV
Sbjct: 225 IKTVAQKKAEKKERERKKRDEEKAKLRKLKEKEELETGKKDQSKQKESQRKFEEETVKSK 284
Query: 333 LSKSQSILISTSATASSKKTIEDRNIKNKKSTNNRASSASARLMTSEFLKKSSSKRRTPS 392
++ ++ ++ A + ED N +KK + + +K K++ PS
Sbjct: 285 VTVDTGVIPASEEKAETPTAAEDDNEGDKKKKDKKKKKGEKE-------EKEKEKKKGPS 337
Query: 393 TTT---SSHYLGTLKVLDQKPSQKQSIEPDRADNIRAA------VYQEWLEKKNVYLHEM 443
T L LK +++ +++ R + + A + QE E+K E
Sbjct: 338 KATVKAMQEALAKLKEEEERQKREEEERIKRLEELEAKRKEEERLEQEKRERKKQ--KEK 395
Query: 444 HRIKRIESENLRIQNEQKKAAKREEALASFEAWKAMKEKEAKKIAAKKR--LEEKNKKKT 501
R +R++ E + Q++A R EA + + E +K KKR E+K +KK
Sbjct: 396 ERKERLKKEGKLLTKSQREARARAEATLKLLQAQGV-EVPSKDSLPKKRPIYEDKKRKKI 454
Query: 502 EEENAARK-GEALQ---------------------------------AFEKWKEKKMEYL 527
++ +++ E+++ + W+ +
Sbjct: 455 PQQLESKEVSESMELCAAVEVMEQGVPEKEETPPPVEPEEEEDTEDAGLDDWEAMASDEE 514
Query: 528 KEK---NRKEREYERAKKQKEEETVAEKKKDNLTAVEKWNEKKEAFFKQKEKEKINEKRK 584
EK N+ E + +++EEE E++ + E+ + E +E EK+++++
Sbjct: 515 TEKVEGNKVHIEVKENPEEEEEEEEEEEEDEESEEEEEEEGESEGSEGDEEDEKVSDEKD 574
Query: 585 EELKRAEKKDKDKQAINEYEKWLENKEKQERIERKQKKR 623
+K K+ + +EY+ +++ K+ER K K+R
Sbjct: 575 SGKTLDKKPSKEMSSDSEYDS-DDDRTKEERAYDKAKRR 612
Score = 39.7 bits (91), Expect = 0.009
Identities = 47/206 (22%), Positives = 93/206 (45%), Gaps = 25/206 (12%)
Query: 452 ENLRIQNEQKKAAKREEALASFEAWKAMKEKEAK-KIAAKKRLEEKNKKKTEEE----NA 506
E ++++KK K ++ + +++K++K K AK ++E + +++
Sbjct: 89 EEFTSKDKKKKGQKGKKQSFDDNDSEELEDKDSKSKKTAKPKVEMYSGSDDDDDFNKLPK 148
Query: 507 ARKGEALQAFEKWK-----EKKMEYLKEKNRKEREYERAKKQKEEETVAEKKKDNLTA-- 559
KG+A ++ +KW E + +KE++R E + E + +K N
Sbjct: 149 KAKGKAQKSNKKWDGSEEDEDNSKKIKERSRINSSGESGDESDEFLQSRKGQKKNQKNKP 208
Query: 560 ---VEKWNEKKEAFFKQK--------EKEKINEKRKEELKRAEKKDKDKQAINEYEK-WL 607
+E NE +A FK K +KE+ +KR EE K +K K+K+ + +K
Sbjct: 209 GPNIESGNEDDDASFKIKTVAQKKAEKKERERKKRDEE-KAKLRKLKEKEELETGKKDQS 267
Query: 608 ENKEKQERIERKQKKRHSFLESEALP 633
+ KE Q + E + K +++ +P
Sbjct: 268 KQKESQRKFEEETVKSKVTVDTGVIP 293
>gi|109134347 NY-REN-58 antigen [Homo sapiens]
Length = 701
Score = 71.2 bits (173), Expect = 3e-12
Identities = 107/531 (20%), Positives = 230/531 (43%), Gaps = 64/531 (12%)
Query: 130 SESQNKDEEFEK--DKIKMKPKPRILSIKSTSSAENNSLDTDDHFKPSPRPRSMLKKKSH 187
SE +++ EE+ + D+ K+K + I ++ N L D K S R + ++K +
Sbjct: 160 SEFEHQKEEYARILDEGKIKYESEIARLEEDKEELRNQLLNVDLTKDSKRVEQLAREKVY 219
Query: 188 MEEK-DGLEDKETALSEELELHSAPSSLPTPNGIQLEAEKKAFSENLDPEDSCLTSLASS 246
+ +K GLE + L E E A ++ AE +A +L+ E A
Sbjct: 220 LCQKLKGLEAEVAELKAEKENSEAQVENAQRIQVRQLAEMQATVRSLEAEKQSANLRAER 279
Query: 247 SLKQILGDSFSPGSEGNASGKDPNEEITENHNSLKSDENKENSFSADHVTTAVEKSKESQ 306
K++ S E+ T N L E + N+ S+ ++ S + +
Sbjct: 280 LEKELQSSS---------------EQNTFLINKLHKAEREINTLSSK--VKELKHSNKLE 322
Query: 307 VTADDLEEEKAKAELIMDDDRTVDPLLSKSQSILISTSATASSKKTIEDRNIKNKKSTNN 366
+T LE +AK+EL + ++ L I +A K + +++ + +
Sbjct: 323 ITDIKLETARAKSELERERNKIQSELDGLQSDNEILKAAVEHHKVLLVEKDRELIRKVQA 382
Query: 367 RASSASARLMTSEFLKKSSSKRRTPSTTTSSHYLGTLKVLDQKPSQKQSIEPDRADNIRA 426
+L+ + K R L +KV + +QS + + +RA
Sbjct: 383 AKEEGYQKLVVLQDEKLELENRLAD--------LEKMKV--EHDVWRQSEKDQYEEKLRA 432
Query: 427 AVYQEWLEKKNVYLHEMHRIKRIESENLRIQNEQKKAAKREEALASFEAWK----AMKEK 482
+ E + +K + + R+K ++ + + I+N +K+ + + + + ++ +
Sbjct: 433 SQMAEEITRKEL---QSVRLK-LQQQIVTIENAEKEKNENSDLKQQISSLQIQVTSLAQS 488
Query: 483 EAKKIAAKKRLEEKNKKKTEE----ENAARKGEALQAFEKWKEKKMEYLKEKNR------ 532
E + + + L+E ++ +E + A K + L+A + +EK++++L+EK++
Sbjct: 489 ENDLLNSNQMLKEMVERLKQECRNFRSQAEKAQ-LEAEKTLEEKQIQWLEEKHKLHERIT 547
Query: 533 -KEREYERAKKQKEEETVAEKKKDNLTAVEKWNEKKEAFFKQKEKEKINEKRKEELKRAE 591
+E +Y +AK++ + +A+KK+ +L +E K + +EK ++ E +KEEL
Sbjct: 548 DREEKYNQAKEKLQRAAIAQKKRKSL------HENK--LKRLQEKVEVLEAKKEEL---- 595
Query: 592 KKDKDKQAINEYEKWLENKEKQERIERKQKKRHSFLESEALPPWSPPSRTV 642
+ + Q +N E+ + ++ + ++RH+ S L P PP+ ++
Sbjct: 596 --ETENQVLNRQNVPFEDYTRLQKRLKDIQRRHNEFRSLILVPNMPPTASI 644
>gi|109134355 NY-REN-58 antigen [Homo sapiens]
Length = 701
Score = 71.2 bits (173), Expect = 3e-12
Identities = 107/531 (20%), Positives = 230/531 (43%), Gaps = 64/531 (12%)
Query: 130 SESQNKDEEFEK--DKIKMKPKPRILSIKSTSSAENNSLDTDDHFKPSPRPRSMLKKKSH 187
SE +++ EE+ + D+ K+K + I ++ N L D K S R + ++K +
Sbjct: 160 SEFEHQKEEYARILDEGKIKYESEIARLEEDKEELRNQLLNVDLTKDSKRVEQLAREKVY 219
Query: 188 MEEK-DGLEDKETALSEELELHSAPSSLPTPNGIQLEAEKKAFSENLDPEDSCLTSLASS 246
+ +K GLE + L E E A ++ AE +A +L+ E A
Sbjct: 220 LCQKLKGLEAEVAELKAEKENSEAQVENAQRIQVRQLAEMQATVRSLEAEKQSANLRAER 279
Query: 247 SLKQILGDSFSPGSEGNASGKDPNEEITENHNSLKSDENKENSFSADHVTTAVEKSKESQ 306
K++ S E+ T N L E + N+ S+ ++ S + +
Sbjct: 280 LEKELQSSS---------------EQNTFLINKLHKAEREINTLSSK--VKELKHSNKLE 322
Query: 307 VTADDLEEEKAKAELIMDDDRTVDPLLSKSQSILISTSATASSKKTIEDRNIKNKKSTNN 366
+T LE +AK+EL + ++ L I +A K + +++ + +
Sbjct: 323 ITDIKLETARAKSELERERNKIQSELDGLQSDNEILKAAVEHHKVLLVEKDRELIRKVQA 382
Query: 367 RASSASARLMTSEFLKKSSSKRRTPSTTTSSHYLGTLKVLDQKPSQKQSIEPDRADNIRA 426
+L+ + K R L +KV + +QS + + +RA
Sbjct: 383 AKEEGYQKLVVLQDEKLELENRLAD--------LEKMKV--EHDVWRQSEKDQYEEKLRA 432
Query: 427 AVYQEWLEKKNVYLHEMHRIKRIESENLRIQNEQKKAAKREEALASFEAWK----AMKEK 482
+ E + +K + + R+K ++ + + I+N +K+ + + + + ++ +
Sbjct: 433 SQMAEEITRKEL---QSVRLK-LQQQIVTIENAEKEKNENSDLKQQISSLQIQVTSLAQS 488
Query: 483 EAKKIAAKKRLEEKNKKKTEE----ENAARKGEALQAFEKWKEKKMEYLKEKNR------ 532
E + + + L+E ++ +E + A K + L+A + +EK++++L+EK++
Sbjct: 489 ENDLLNSNQMLKEMVERLKQECRNFRSQAEKAQ-LEAEKTLEEKQIQWLEEKHKLHERIT 547
Query: 533 -KEREYERAKKQKEEETVAEKKKDNLTAVEKWNEKKEAFFKQKEKEKINEKRKEELKRAE 591
+E +Y +AK++ + +A+KK+ +L +E K + +EK ++ E +KEEL
Sbjct: 548 DREEKYNQAKEKLQRAAIAQKKRKSL------HENK--LKRLQEKVEVLEAKKEEL---- 595
Query: 592 KKDKDKQAINEYEKWLENKEKQERIERKQKKRHSFLESEALPPWSPPSRTV 642
+ + Q +N E+ + ++ + ++RH+ S L P PP+ ++
Sbjct: 596 --ETENQVLNRQNVPFEDYTRLQKRLKDIQRRHNEFRSLILVPNMPPTASI 644
>gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo
sapiens]
Length = 668
Score = 70.5 bits (171), Expect = 5e-12
Identities = 77/378 (20%), Positives = 168/378 (44%), Gaps = 35/378 (9%)
Query: 278 NSLKSDENKENSFSADHVTTAVEKSK-ESQVTADDLEEEKAKAELIMDDDRT---VDPLL 333
N++ +E KE + VE K E Q+ +L+ + +A+L++ + D L
Sbjct: 212 NTITDEELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLG 271
Query: 334 SKSQSILISTSATASSKKTIEDRNIKNKKST---NNRASSASARLMTSEFLKKSSSKRRT 390
+ QS+ A + N + ++ + ++ E + ++
Sbjct: 272 KELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIR 331
Query: 391 PSTTTSSHYLGTLKVLDQKPSQKQSIEPDRADNIRAAVYQEWLEKKNVY-----LHEMHR 445
+ ++K +++ + ++ + +R W +++ + +HE +
Sbjct: 332 EQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRLEEMMWEKEEKIRELEEKMHEQEK 391
Query: 446 I-----KRIESENLRIQN---EQKKAAKREEALASFEAWKAMKEKEAK------KIAAKK 491
I KR E E +R Q EQ+ R+E E + ++E+E K KI ++
Sbjct: 392 IREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIR-EQEEKIREQEKKMWRQEEKIHEQE 450
Query: 492 RLEEKNKKKTEEENAARKGEALQAFEKWKEKKMEYLKEKNRKERE---YERAKKQKEEET 548
++ E+ K++ +EE ++ + + E W++K+ + +EK RK+ E + K +EE
Sbjct: 451 KIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKMHEQEKIRKQEEKVWRQEEKMHDQEEK 510
Query: 549 VAEKKKDNLTAVEKWNEKKEAFFKQKEKEKINEKRKEELKRAEKKDKDKQAINEYEKWLE 608
+ E+++ EK E++E ++++EKI E+ + ++ EK + ++ + E EK
Sbjct: 511 IREQEEKMWRQEEKIREQEEKI--REQEEKIREQEEMMQEQEEKMGEQEEKMQEQEKMRR 568
Query: 609 NKEK---QERIERKQKKR 623
+EK QE R+QK++
Sbjct: 569 QEEKIREQEEKIREQKEK 586
Score = 68.9 bits (167), Expect = 1e-11
Identities = 105/494 (21%), Positives = 208/494 (42%), Gaps = 70/494 (14%)
Query: 166 LDTDDHFKPSPRPRSMLKKKSH-MEEKDGLEDKETALSEELELHSAPSSLPTPNGIQLEA 224
L T H P + +H M K+ + K E+L H P + P+ +
Sbjct: 27 LPTHPHLPTHPHLPTHPHLPTHPMMSKETRQSKLAEAKEQLTDHH-PQTNPSVGTAASDT 85
Query: 225 EKKAFSENLDPEDSCLTSLASSSLKQILGDSFSPGSEGNASGKDPN---EEITENHNSLK 281
+KK + +PE + TS G SP E AS + E+ ++++
Sbjct: 86 KKKKINNGTNPETT--TS----------GGCHSPEDEQKASHQHQEALRRELEAQVHTIR 133
Query: 282 -----SDENKENSFSADHVTTAVEKSKESQVT--------ADDLEEE-KAKAELIMDDDR 327
E + + + H +E ++ A +LE+ A A DR
Sbjct: 134 ILTCQKTELQMALYYSQHAVKQLEGEARDLISRLHDSWKFAGELEQALSAVATQKKKADR 193
Query: 328 TVDPLLSKSQSILISTSATASSKKTIEDRNIKNKKSTNNRASSASARLMTSEFLKKSSSK 387
++ L + ++ + + + ++++N K ++ S S + + LK+ +
Sbjct: 194 YIEELTKERDALSLELYRNTITDEELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLER 253
Query: 388 RRTPSTTTSSHYLGTLKVLDQKPSQKQSIEPDRADNIRAAVYQEWLEKKNVY--LHEMHR 445
+ +L Q+ Q ++ + +A Q +E+ ++ L++
Sbjct: 254 AKL--------------LLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQE 299
Query: 446 IKRIESENLRIQNEQKKAAKREEALASFEAWKAMKEKEAKKIAAKKRLEEKNKK-KTEEE 504
K E +IQ ++K ++EE + E + ++E+E K ++ + EK +K + +EE
Sbjct: 300 EKMWRQEE-KIQEWEEKIQEQEEKIREQE--EKIREQEEKMRRQEEMMWEKEEKMRRQEE 356
Query: 505 NAARKGEALQAFEKWKEKKMEYLKEKNRKEREYERAKKQKEEETVAEKKKDNLTAVEKWN 564
K E ++ E+ +K E ++E K E E+ ++Q+E+ EK ++ EK
Sbjct: 357 MMWEKEEKMRRLEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQ----EKRQ 412
Query: 565 EKKEAFFKQKEK-----EKINEKRKEELKRAEKKDKDKQAINEYEKWLENKE-------- 611
E++ ++Q+EK EKI E+ K ++ R E+K +++ I E EK E +E
Sbjct: 413 EQEAKMWRQEEKIREQEEKIREQEK-KMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKI 471
Query: 612 -KQERIERKQKKRH 624
+QE I R+++K H
Sbjct: 472 REQEEIWRQKEKMH 485
Score = 63.9 bits (154), Expect = 4e-10
Identities = 50/204 (24%), Positives = 104/204 (50%), Gaps = 12/204 (5%)
Query: 417 EPDRADNIRAAVYQEWLEKKNVY-LHEMHRIKRIESENLRIQNEQKKAAKREEALASFEA 475
E R + R + W +++ + E+ R K E +I+ +++K ++EE + E
Sbjct: 450 EKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKMHEQEKIRKQEEKVWRQEEKMHDQE- 508
Query: 476 WKAMKEKEAKKIAAKKRLEEKNKKKTEEENAARKGEALQAFEKWKEKKMEYLKEKNRKER 535
+ ++E+E K ++++ E+ +K E+E R+ E + +++ E + E+ K +
Sbjct: 509 -EKIREQEEKMWRQEEKIREQEEKIREQEEKIREQEEMM------QEQEEKMGEQEEKMQ 561
Query: 536 EYERAKKQKEEETVAEKKKDNLTAVEKWNEKKEAFFKQKEKEKINEKRKEELKRAEKKDK 595
E E+ ++Q EE + E+++ EK E++E ++Q+EK + E+ +E + + +
Sbjct: 562 EQEKMRRQ--EEKIREQEEKIREQKEKIREQEEKIWEQEEKIREQEEMMQEQEEKMWEQE 619
Query: 596 DKQAINEYEKWLENKEKQERIERK 619
+K E EK E +EK R E K
Sbjct: 620 EKMCEQE-EKMQEQEEKMRRQEEK 642
Score = 62.0 bits (149), Expect = 2e-09
Identities = 53/251 (21%), Positives = 117/251 (46%), Gaps = 19/251 (7%)
Query: 404 KVLDQKPSQKQSIEP--------DRADNIRAAVYQEWLEKKNVYLHEMHRIKRIESENLR 455
K+ +Q+ Q+Q + ++ + IR + W +++ ++ E R + E
Sbjct: 404 KIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEE 463
Query: 456 IQNEQKKAAKREEALASFEAWKAMKEKEAKKIAAKKRLEEKNKKKTEEENAARKGEALQA 515
+ +++K ++EE E M E+E + +K ++ K +EE + E +
Sbjct: 464 MWRQEEKIREQEEIWRQKEK---MHEQEKIRKQEEKVWRQEEKMHDQEEKIREQEEKMWR 520
Query: 516 FEKWKEKKMEYLKEKNRKEREYERAKKQKEEETVAEKKKDNLTAVEKWNEKKEAFFKQKE 575
E+ ++ E ++E+ K RE E +++EE+ +++K + EK ++E +Q+E
Sbjct: 521 QEEKIREQEEKIREQEEKIREQEEMMQEQEEKMGEQEEK--MQEQEKMRRQEEKIREQEE 578
Query: 576 -----KEKINEKRKEELKRAEK-KDKDKQAINEYEKWLENKEKQERIERKQKKRHSFLES 629
KEKI E+ ++ ++ EK +++++ + EK E +EK E K +++ +
Sbjct: 579 KIREQKEKIREQEEKIWEQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRR 638
Query: 630 EALPPWSPPSR 640
+ W R
Sbjct: 639 QEEKMWEQEVR 649
Score = 60.8 bits (146), Expect = 4e-09
Identities = 47/222 (21%), Positives = 120/222 (54%), Gaps = 14/222 (6%)
Query: 404 KVLDQKPSQKQSIEPDRADNIRAAVYQEWLEKKNVYLHEMHRIKRIESENLR----IQNE 459
K+ +++ Q+Q + + IR QE + ++ +HE +I++ E + R + ++
Sbjct: 451 KIREEEKRQEQEEMWRQEEKIRE---QEEIWRQKEKMHEQEKIRKQEEKVWRQEEKMHDQ 507
Query: 460 QKKAAKREEALASFEAWKAMKEKEAKKIAAKKRLEEKNKKKTEEENAARKGEALQAFEKW 519
++K ++EE + E K +++E + +K E++ + +EE + E +Q EK
Sbjct: 508 EEKIREQEEKMWRQEE-KIREQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMQEQEKM 566
Query: 520 KEKKMEYLKEKNRKEREYERAKKQKEEETVAEKKKDNLTAVEKWNEKKEAFFKQKEKEKI 579
+ ++ E ++E+ K RE ++ K +++EE + E+++ E E++E ++Q+EK
Sbjct: 567 RRQE-EKIREQEEKIRE-QKEKIREQEEKIWEQEEKIREQEEMMQEQEEKMWEQEEKMCE 624
Query: 580 NEKRKEELKRAEKKDKDKQAINEYEKWLENKEKQERIERKQK 621
E++ +E + ++ ++K +E+ + ++++E+++ Q+
Sbjct: 625 QEEKMQEQEEKMRRQEEKM----WEQEVRLRQQEEKMQEHQE 662
Score = 52.0 bits (123), Expect = 2e-06
Identities = 71/336 (21%), Positives = 138/336 (41%), Gaps = 56/336 (16%)
Query: 331 PLLSKSQSILISTSATASSKKTIEDRNIKNKKSTNNRASSASARLMTSEFLKKSSSKRRT 390
P++SK S A +K+ + D + + S AS KK +
Sbjct: 49 PMMSKETR----QSKLAEAKEQLTDHHPQTNPSVGTAASDTK---------KKKINNGTN 95
Query: 391 PSTTTSSHYLGTLKVLDQKPSQKQSIEPDRAD------NIRAAVYQEWLEKKNVYLHEMH 444
P TTTS G D++ + Q E R + IR Q+ E + + H
Sbjct: 96 PETTTSG---GCHSPEDEQKASHQHQEALRRELEAQVHTIRILTCQK-TELQMALYYSQH 151
Query: 445 RIKRIESENL----RIQNEQKKAAKREEALASFEAWKAMKEKEAKKIAAKK---RLEEKN 497
+K++E E R+ + K A + E+AL++ K ++ +++ ++ LE
Sbjct: 152 AVKQLEGEARDLISRLHDSWKFAGELEQALSAVATQKKKADRYIEELTKERDALSLELYR 211
Query: 498 KKKTEEENAARKGEALQAFEKWKEKKMEYLKEKNRKEREYERAKKQ-------------- 543
T+EE + + + + + +K E +R+ ERAK
Sbjct: 212 NTITDEELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLG 271
Query: 544 KEEETVAEKKKDNLTAVEKWN----EKKEAFFKQKEKEKINEKRKEELKRAEKKDKDKQA 599
KE ++V+ K + + E WN +++E ++Q+EK ++ +E+++ E+K ++++
Sbjct: 272 KELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKI---QEWEEKIQEQEEKIREQE- 327
Query: 600 INEYEKWLENKEKQERIERKQKKRHSFLESEALPPW 635
EK E +EK R E ++ + + W
Sbjct: 328 ----EKIREQEEKMRRQEEMMWEKEEKMRRQEEMMW 359
Score = 50.1 bits (118), Expect = 6e-06
Identities = 46/209 (22%), Positives = 102/209 (48%), Gaps = 22/209 (10%)
Query: 404 KVLDQKPSQKQSIEPDRADNIRAAVYQEWLEKKNVYLHE----------MHRIKRIESEN 453
K+ +Q+ +Q + + IR + W +++ ++ E + ++I +
Sbjct: 470 KIREQEEIWRQKEKMHEQEKIRKQEEKVWRQEEKMHDQEEKIREQEEKMWRQEEKIREQE 529
Query: 454 LRIQNEQKKAAKREEALASFEAWKAMKEKEAKKIAAKKRLEEKNKKKTEEENAARKGEAL 513
+I+ +++K ++EE + E + M E+E K +K ++ K + +EE + E +
Sbjct: 530 EKIREQEEKIREQEEMMQEQE--EKMGEQEEKMQEQEKMRRQEEKIREQEEKIREQKEKI 587
Query: 514 QAFEKWKEKKMEYLKEKNRKEREYERAKKQKEEETVAEKKKDNLTAVEKWNEKKEAFFKQ 573
+ +E+K+ +EK R++ E Q++EE + E+++ EK E++E +Q
Sbjct: 588 RE----QEEKIWEQEEKIREQEE----MMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQ 639
Query: 574 KEK--EKINEKRKEELKRAEKKDKDKQAI 600
+EK E+ R++E K E ++ + AI
Sbjct: 640 EEKMWEQEVRLRQQEEKMQEHQEHLEAAI 668
>gi|42560244 peptidylprolyl isomerase G [Homo sapiens]
Length = 754
Score = 70.5 bits (171), Expect = 5e-12
Identities = 88/428 (20%), Positives = 184/428 (42%), Gaps = 58/428 (13%)
Query: 244 ASSSLKQILGDSFSPGSEGNASGKDPNEEITENHNSLKSDENKENSFSADHVTTAVEKSK 303
+SSS DS S ++S +E TE + + ++++NS +KSK
Sbjct: 193 SSSSSSSSSSDSDSSSDSQSSSDSSDSESATEEKSKKRKKKHRKNSRKHKKEKKKRKKSK 252
Query: 304 ESQVTADDLEEEKAKAELIMDDDRTVDPLLSKSQSILISTSATASSK--KTIEDRNIKNK 361
+S + + E +A+ + + + P + +++ ++ + A K K E +
Sbjct: 253 KSASSESEAENLEAQPQSTVRPEEI--PPIPENRFLMRKSPPKADEKERKNREREREREC 310
Query: 362 KSTNNRASSASARLMTSEFLKKSSSKR----RTPSTTTSSHYLGTLKVLDQKPSQKQSIE 417
N++ +S RL+ + +K + RTPS + S + + P +Q ++
Sbjct: 311 NPPNSQPASYQRRLLVTRSGRKIKGRGPRRYRTPSRSRSRD---RFRRSETPPHWRQEMQ 367
Query: 418 PDRADNIRAAVYQEWLEKKNVYLHEMH-------RIK-------RIESENLRIQNEQKKA 463
RA +R + + W++ L+E+ R+K R SE+ +NE++K
Sbjct: 368 --RAQRMRVSSGERWIKGDKSELNEIKENQRSPVRVKERKITDHRNVSESPNRKNEKEKK 425
Query: 464 AKREEALASFEAWKAMKEKEAK-KIAAKKRLEEKNKKKTEEENAARKGEALQAFEKWKEK 522
K ++ + + EK+ K K KKR + K++ K++E++ +++ ++ + +EK
Sbjct: 426 VKDHKSNSKERDIRRNSEKDDKYKNKVKKRAKSKSRSKSKEKSKSKERDSKH--NRNEEK 483
Query: 523 KMEYLKE----KNRKEREYERAKKQKEEETVAEKKKDNLTAVEKWNEKKEAFFKQKE--- 575
+M + +N KE+E + K K++E K+K K NE + K+K+
Sbjct: 484 RMRSRSKGRDHENVKEKEKQSDSKGKDQERSRSKEKSKQLE-SKSNEHDHSKSKEKDRRA 542
Query: 576 ------------KEKINEKRKEELK--------RAEKKDKDKQAINEYEKWLENKEKQER 615
K N + +E + R+ D+D+ EY ++ E + ++
Sbjct: 543 QSRSRECDITKGKHSYNSRTRERSRSRDRSRRVRSRTHDRDRSRSKEYHRYREQEYRRRG 602
Query: 616 IERKQKKR 623
R +++R
Sbjct: 603 RSRSRERR 610
Score = 62.4 bits (150), Expect = 1e-09
Identities = 100/575 (17%), Positives = 214/575 (37%), Gaps = 48/575 (8%)
Query: 35 RSARQRSSEYSDDFDSDEIVSLGDFSDTSADENSVNKKMNDFHISDDEEKNPSKLLFLKT 94
+S+ SS SD S + S D SD+ + +KK H + + K K+
Sbjct: 192 KSSSSSSSSSSDSDSSSDSQSSSDSSDSESATEEKSKKRKKKHRKNSRKHKKEKKKRKKS 251
Query: 95 NKSNGNITKDE-----PVCAIKNEEEMAPDGCEDIVVKS---FSESQNKDEEFEKDKIKM 146
KS + ++ E P ++ EE ++ KS E + K+ E E+++
Sbjct: 252 KKSASSESEAENLEAQPQSTVRPEEIPPIPENRFLMRKSPPKADEKERKNRERERERECN 311
Query: 147 KPKPRILSIKSTSSAENNSLDTDDHFKPSPRPRSMLKKKSHMEEKDGLEDKETALSEELE 206
P +S + L T K R + S +D ET E
Sbjct: 312 PPN------SQPASYQRRLLVTRSGRKIKGRGPRRYRTPSRSRSRDRFRRSETPPHWRQE 365
Query: 207 LHSAPSSLPTPNGIQLEAEKKAFSENLDPEDSCLTSLASSSLKQILGDSFSPGSEGNASG 266
+ A + ++ +K +E + + S + +K+ SE
Sbjct: 366 MQRAQRMRVSSGERWIKGDKSELNEIKENQRSPV------RVKERKITDHRNVSESPNRK 419
Query: 267 KDPNEEITENHNSLKSDENKENSFSADHVTTAVEKSKESQVTADDLEEEKAKAELIMDDD 326
+ +++ ++ ++ K + + NS D V+K +S+ + E+ K+K +
Sbjct: 420 NEKEKKVKDHKSNSKERDIRRNSEKDDKYKNKVKKRAKSKSRSKSKEKSKSKERDSKHNR 479
Query: 327 RTVDPLLSKS-----QSILISTSATASSKKTIEDRNIKNKKSTNNRASSASARLMTSEFL 381
+ S+S +++ + S K E K K S+ + E
Sbjct: 480 NEEKRMRSRSKGRDHENVKEKEKQSDSKGKDQERSRSKEKSKQLESKSNEHDHSKSKEKD 539
Query: 382 KKSSSKRRTPSTTTSSHYLGTLKVLDQKPSQKQSIEPDRADNIRAAVYQEWLEKKNVYLH 441
+++ S+ R T H + ++++S DR+ +R+ H
Sbjct: 540 RRAQSRSRECDITKGKHSYNS-------RTRERSRSRDRSRRVRSRT------------H 580
Query: 442 EMHRIKRIESENLRIQNEQKKAAKREEALASFEAWKAMKEKEAKKIAAKKRLEEKNKKKT 501
+ R + E R Q +++ R + K++ ++ ++ E+++ +
Sbjct: 581 DRDRSRSKEYHRYREQEYRRRGRSRSRERRTPPGRSRSKDRRRRRRDSRSSEREESQSRN 640
Query: 502 EEENAARKGEALQAFEKWKEKKMEYLKEKNRKEREYERAKKQKEEETVAEKKKDNLTAVE 561
+++ ++ ++ E + +K Y K ++ R KK +++ K K +
Sbjct: 641 KDKYRNQESKSSHRKENSESEKRMYSKSRDHNSSNNSREKKADRDQSPFSKIKQS----S 696
Query: 562 KWNEKKEAFFKQKEKEKINEKRKEELKRAEKKDKD 596
+ NE K + K KE EKI ++E ++++ ++ D
Sbjct: 697 QDNELKSSMLKNKEDEKIRSSVEKENQKSKGQEND 731
Score = 47.8 bits (112), Expect = 3e-05
Identities = 116/596 (19%), Positives = 242/596 (40%), Gaps = 85/596 (14%)
Query: 101 ITKDEPVCAIKNEEEMAPDGCEDIVVKSFSESQ--NKDEEFEKDKIKMKPKPRILSIKST 158
I+ E V I+N++ D K F+E + + E K K+K + K R S S+
Sbjct: 145 ISGQEVVREIENQKT-------DAASKPFAEVRILSCGELIPKSKVKKEEKKRHKSSSSS 197
Query: 159 SSAENNSLDTDDHFKPSP--------RPRSMLKKKSHM--------EEKDGLEDKETALS 202
SS+ ++S + D S +S +KK H E+K + K++A S
Sbjct: 198 SSSSSDSDSSSDSQSSSDSSDSESATEEKSKKRKKKHRKNSRKHKKEKKKRKKSKKSASS 257
Query: 203 E-ELE-LHSAPSSLPTPNGIQL----------------EAEKKAFSENLDPEDSCLTSLA 244
E E E L + P S P I E E+K + E + S
Sbjct: 258 ESEAENLEAQPQSTVRPEEIPPIPENRFLMRKSPPKADEKERKNRERERERECNPPNSQP 317
Query: 245 SSSLKQILGDSFSPGSEGNASGKDPNEEITENHNSLKSDENKENSFSADHVTTAVEKSKE 304
+S +++L S G+ P T + + +S + S + H +++++
Sbjct: 318 ASYQRRLLVTR----SGRKIKGRGPRRYRTPSRS--RSRDRFRRSETPPHWRQEMQRAQR 371
Query: 305 SQVTADDLEEEKAKAELIMDDDRTVDPLLSKSQSILISTSATAS-SKKTIEDRNIKNKKS 363
+V++ + + K+EL + P+ K + I + + S ++K +++ +K+ KS
Sbjct: 372 MRVSSGERWIKGDKSELNEIKENQRSPVRVKERKITDHRNVSESPNRKNEKEKKVKDHKS 431
Query: 364 TNN----RASSASARLMTSEFLKKSSSKRRTPSTTTSS-------HYLGTLKVL------ 406
+ R +S ++ K++ SK R+ S S H K +
Sbjct: 432 NSKERDIRRNSEKDDKYKNKVKKRAKSKSRSKSKEKSKSKERDSKHNRNEEKRMRSRSKG 491
Query: 407 ----DQKPSQKQSIEPDR-ADNIRAAVYQEWLEKKNVYLHEMHRIKRIESENLRIQNEQK 461
+ K +KQS + + R+ + LE K+ H + + ++ R Q+ +
Sbjct: 492 RDHENVKEKEKQSDSKGKDQERSRSKEKSKQLESKS----NEHDHSKSKEKDRRAQSRSR 547
Query: 462 KA--AKREEALASFEAWKAMKEKEAKKIAAKKRLEEKNKKKTEEENAARKGE-ALQAFEK 518
+ K + + S ++ ++++ + R ++++ +++E + R+ E + +
Sbjct: 548 ECDITKGKHSYNSRTRERSRSRDRSRRV--RSRTHDRDRSRSKEYHRYREQEYRRRGRSR 605
Query: 519 WKEKKMEYLKEKNRKEREYERAKKQKEEETVAEKKKDNLTAVE-KWNEKKEAFFKQKEK- 576
+E++ + +++ R R + E E + KD E K + +KE +K
Sbjct: 606 SRERRTPPGRSRSKDRRRRRRDSRSSEREESQSRNKDKYRNQESKSSHRKENSESEKRMY 665
Query: 577 EKINEKRKEELKRAEKKDKDKQAINEYEKWLENKE-KQERIERKQ-KKRHSFLESE 630
K + R +K D+D+ ++ ++ ++ E K ++ K+ +K S +E E
Sbjct: 666 SKSRDHNSSNNSREKKADRDQSPFSKIKQSSQDNELKSSMLKNKEDEKIRSSVEKE 721
Score = 38.9 bits (89), Expect = 0.015
Identities = 29/179 (16%), Positives = 78/179 (43%), Gaps = 20/179 (11%)
Query: 477 KAMKEKEAKKIAAKKRLEEKNKKKTEEENAARKGEALQAFEKWKEKKMEYLKEKNRKERE 536
K ++K K ++ + ++ ++++ ++ A E+ +K+ + ++ +RK ++
Sbjct: 184 KKEEKKRHKSSSSSSSSSSDSDSSSDSQSSSDSSDSESATEEKSKKRKKKHRKNSRKHKK 243
Query: 537 YERAKKQKEEETVAEKKKDNLTAVEKWNEKKE--------AFFKQKEKEKINEKRKEELK 588
++ +K+ ++ +E + +NL A + + E F +K K +EK ++ +
Sbjct: 244 EKKKRKKSKKSASSESEAENLEAQPQSTVRPEEIPPIPENRFLMRKSPPKADEKERKNRE 303
Query: 589 RAEKKD---KDKQAINEYEKWLENKE---------KQERIERKQKKRHSFLESEALPPW 635
R +++ + Q + + L + ++ R + + R F SE P W
Sbjct: 304 RERERECNPPNSQPASYQRRLLVTRSGRKIKGRGPRRYRTPSRSRSRDRFRRSETPPHW 362
>gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo
sapiens]
Length = 570
Score = 69.3 bits (168), Expect = 1e-11
Identities = 67/375 (17%), Positives = 169/375 (45%), Gaps = 40/375 (10%)
Query: 278 NSLKSDENKENSFSADHVTTAVEKSK-ESQVTADDLEEEKAKAELIMDDDRT---VDPLL 333
N++ +E KE + VE K E Q+ +L+ + +A+L++ + D L
Sbjct: 200 NTITDEELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLG 259
Query: 334 SKSQSILISTSATASSKKTIEDRNIKNKKSTNNRASSASARLMTSEFLKKSSSKRRTPST 393
+ QS+ +A + +E+ + N+ + E +K +
Sbjct: 260 KELQSV------SAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEREEKIQEQEEK--- 310
Query: 394 TTSSHYLGTLKVLDQKPSQKQSIEPDRADNIRAAVYQEWLEKKNVY-----LHEMHRIKR 448
++ ++K +++ + ++ + +R W +++ + +HE +I+
Sbjct: 311 ---------IREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIRE 361
Query: 449 IESENLRIQNEQKKAAKREEALASFEAWKAMKEKEAKKIAAKKRLEEKNKKKTE-EENAA 507
E + + +++ ++E+ + + ++E+E K ++ ++E+ +K E EE
Sbjct: 362 QEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMW 421
Query: 508 RKGEALQAFEKWKEKKMEYLKEKNRKEREYERAKK------QKEEETVAEKKKDNLTAVE 561
+ E +Q E+ ++ E ++E+ +K RE E + Q++EE + E++
Sbjct: 422 EQEEEMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMGEQEGKMCEQEA 481
Query: 562 KWNEKKEAFFKQKEKEKINEKR----KEELKRAEK--KDKDKQAINEYEKWLENKEKQER 615
K E++E +Q+EK + EK+ +E+++ E+ ++++++ + EK E +EK +
Sbjct: 482 KMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQE 541
Query: 616 IERKQKKRHSFLESE 630
E K +++ + +
Sbjct: 542 QEEKMRRQEEKMREQ 556
Score = 65.1 bits (157), Expect = 2e-10
Identities = 61/224 (27%), Positives = 119/224 (53%), Gaps = 23/224 (10%)
Query: 425 RAAVYQEWLEKKNVYLHEMHRIKRIESENLRIQ---NEQKKAAKREEALASFEAWKAMKE 481
R + E L++KN L E +++ +ESE IQ E K+ +R + L + +A +
Sbjct: 199 RNTITDEELKEKNAKLQE--KLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEAD 256
Query: 482 ---KEAKKIAAKKRLE-EKNK-----KKTEEENAARKGEALQAFEKW---KEKKMEYLKE 529
KE + ++AK + + E+N+ + +EE R+ E +Q E+ +E+K+ +E
Sbjct: 257 HLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEREEKIQEQEEKIREQEE 316
Query: 530 KNRKERE--YERAKKQKEEETVAEKKKDNLTAVEKWNEKKEAFFKQKEKEKINEKRKEEL 587
K R++ E +E+ +K + +E + +K++ + +E+ ++E +Q+EK + EK +E+
Sbjct: 317 KMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQE 376
Query: 588 KRAEKKDKDKQAINEYEKWLENKEK-QERIERKQKKRHSFLESE 630
KR E++ K + EK E +EK +E+ E Q++ E E
Sbjct: 377 KRQEQEAK---MWRQEEKIREQEEKIREQEEMMQEQEEKMGEQE 417
Score = 63.9 bits (154), Expect = 4e-10
Identities = 46/192 (23%), Positives = 109/192 (56%), Gaps = 12/192 (6%)
Query: 447 KRIESENLRIQNEQKKAAKREEALASFEAWKAMKEKEAKKIAAKKRLEEKNKKKTEEENA 506
++I+ +IQ +++K ++EE + E + M EKE K ++ + EK +K E E
Sbjct: 295 EKIQEREEKIQEQEEKIREQEEKMRRQE--EMMWEKEEKMRRQEEMMWEKEEKIRELEEK 352
Query: 507 ARKGEALQAFEKWKEKKMEYLKEKNRKEREY----ERAKKQKEEETVAEKKKDNLTAVEK 562
+ E ++ E+ ++++ + +++ R+E+E + K +++EE + E+++ EK
Sbjct: 353 MHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEMMQEQEEK 412
Query: 563 WNEKKEAFFKQKEKEKINEKRKEELKRAEKKDKDKQ-AINEYEKWLENKEK--QERIERK 619
E++E ++Q+E+ ++++E+++R E+K ++++ I E E+ + +E+ QE+ E+
Sbjct: 413 MGEQEEKMWEQEEE---MQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKM 469
Query: 620 QKKRHSFLESEA 631
++ E EA
Sbjct: 470 GEQEGKMCEQEA 481
Score = 60.5 bits (145), Expect = 5e-09
Identities = 73/313 (23%), Positives = 147/313 (46%), Gaps = 35/313 (11%)
Query: 344 SATASSKKTIEDRNIKNKKSTNNRASSASAR-LMTSEFLKKSSSKRRTPSTTTSSHYLG- 401
SA A+ KK DR I+ + S R +T E LK+ ++K + S
Sbjct: 170 SAVATQKKKA-DRYIEELTKERDALSLELYRNTITDEELKEKNAKLQEKLQLVESEKSEI 228
Query: 402 --TLKVLDQKPSQKQSIEPDRADNIRAAVYQEWLEKKNVYLHEMHRIKRIESENLRIQNE 459
+K L +K + + + P + ++A E ++V +++ E N Q +
Sbjct: 229 QLNVKELKRKLERAKLLLPQQ--QLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQ 286
Query: 460 QKKAAKREEALASFEAWKAMKEKEAKKIAAKKRLEEKNKKKTEEENAARKGEALQAFEKW 519
++K ++EE + E + ++E+E K ++++ + + E+E R+ E + W
Sbjct: 287 EEKMWRQEEKIQERE--EKIQEQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMM----W 340
Query: 520 -KEKKMEYLKEK-NRKEREYERAKKQKEEETVAEKKKDNLTAVEKWN------EKKEAFF 571
KE+K+ L+EK + +E+ E+ +K++EEE + E++K + W E++E
Sbjct: 341 EKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIR 400
Query: 572 KQKE------------KEKINEKRKEELKRAEKKDKDKQAINEYEKWLENKEK--QERIE 617
+Q+E +EK+ E+ +E ++ EK + ++ I E EK + +E+ +E+ E
Sbjct: 401 EQEEMMQEQEEKMGEQEEKMWEQEEEMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEE 460
Query: 618 RKQKKRHSFLESE 630
Q++ E E
Sbjct: 461 MMQEQEEKMGEQE 473
Score = 56.6 bits (135), Expect = 7e-08
Identities = 82/389 (21%), Positives = 173/389 (44%), Gaps = 42/389 (10%)
Query: 273 ITENHNSLKSDENKENSFSADHVTTAVEKSKESQVTADDLEEEKAKAELIMDDDRTVDPL 332
I+ H+S K E + SA A +K K + ++L +E+ L + + D
Sbjct: 152 ISRLHDSWKFAGELEQALSA----VATQKKKADRYI-EELTKERDALSLELYRNTITDEE 206
Query: 333 LSKSQSILISTSATASSKKTIEDRNIKNKKSTNNRASSASARLMTSEFLKKSSSKRRTPS 392
L + + L S+K+ N+K K RA L+ + L+ +
Sbjct: 207 LKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKL----LLPQQQLQAEADHLGKEL 262
Query: 393 TTTSSHYLGTLKV------LDQKPSQKQSIEPDRADNIRAAVYQEWLEKKNVYLHEMHRI 446
+ S+ ++ L+Q+ +K + ++ R QE EK +M R
Sbjct: 263 QSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQE-REEKIQEQEEKIREQEEKMRRQ 321
Query: 447 KRI---ESENLRIQNEQ--KKAAKREEALASFEAWKAMKEKEAKKIAAKKRLEEKNKKKT 501
+ + + E +R Q E +K K E + ++E+E K+ ++++ E+ K++
Sbjct: 322 EEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKR-QEEEKIREQEKRQE 380
Query: 502 EEENAARKGEALQAFEKWKEKKMEYLKEKNRK-----EREYERAKKQKEEETVAEKKKDN 556
+E R+ E ++ E+ ++ E ++E+ K E+ +E+ ++ +E+E ++++
Sbjct: 381 QEAKMWRQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMWEQEEEMQEQEEKMRRQEEK 440
Query: 557 LTAVEKW-NEKKEAFFKQKE-----KEKINEKR----KEELKRAEKKDK---DKQAINEY 603
+ EK E++E +Q+E +EK+ E+ ++E K E+++K ++ I E
Sbjct: 441 IREQEKKIREQEEKIREQEEMMQEQEEKMGEQEGKMCEQEAKMQEQEEKMRRQEEKIREQ 500
Query: 604 EKWLENKEK--QERIERKQKKRHSFLESE 630
EK + +E+ +E+ E Q++ E E
Sbjct: 501 EKKIREQEEKIREQEEMMQEQEEKMWEQE 529
>gi|115298682 HBxAg transactivated protein 2 [Homo sapiens]
Length = 2817
Score = 69.3 bits (168), Expect = 1e-11
Identities = 66/283 (23%), Positives = 141/283 (49%), Gaps = 23/283 (8%)
Query: 357 NIKNKKSTNNRASSASARLMTSEFLKKSSSKRRTPSTT----TSSHYLGTLKVLDQK--P 410
N +NKK T+ +++ S+ + ++ + PS TSSH K+L Q+ P
Sbjct: 360 NNENKKETDEVSNTKSSSQIPAQPSVAKVPYGKGPSFNQERGTSSHLPPPPKLLAQQHPP 419
Query: 411 SQKQSIEPDRADNIRAA--------VYQEWLEKKNVYLHEMHRIKRIESENLRIQNEQKK 462
+Q++ P R + ++++ +++ + R ++ E R EQ+K
Sbjct: 420 PDRQAV-PGRPGPFPSKQQVADEDEIWKQRRRQQSEISAAVERARKRREEEERRMEEQRK 478
Query: 463 AAKREEALASFEAWKAMKEKEAKKIAAKKRLEEKNKKKTEEENAARKGEALQAFEKWKEK 522
AA E+ L + + EK+ ++R EK +++ +E ++ E + EK +E+
Sbjct: 479 AACAEK-LKRLDEKLGILEKQPSPEEIREREREKEREREKELEKEQEQEREKEREKDRER 537
Query: 523 KMEYLKE---KNRKEREYERAKKQKEEETVAEKKKDNLTAVEKWNEKKEAFFKQKEKEKI 579
+ E KE + K+RE E+ +KQ++E+ + E++K+ ++K E+++ +KE+EK+
Sbjct: 538 QQEKEKELEKEQEKQREMEKERKQEKEKEL-ERQKEKEKELQKMKEQEKECELEKEREKL 596
Query: 580 NEK---RKEELKRAEKKDKDKQAINEYEKWLENKEKQERIERK 619
EK R+ L+ +K + + + N+ E+ + ++ R E++
Sbjct: 597 EEKIEPREPNLEPMVEKQESENSCNKEEEPVFTRQDSNRSEKE 639
Score = 67.4 bits (163), Expect = 4e-11
Identities = 55/175 (31%), Positives = 96/175 (54%), Gaps = 29/175 (16%)
Query: 474 EAWKAMKEKEAKKIAA----KKRLEEKNKKKTEEENAARKGEALQAFEKW----KEKKME 525
E WK + ++++ AA +KR EE+ ++ E+ AA + + EK K+ E
Sbjct: 443 EIWKQRRRQQSEISAAVERARKRREEEERRMEEQRKAACAEKLKRLDEKLGILEKQPSPE 502
Query: 526 YLKEKNRKEREYERAKK-QKEEETVAEKKKDNLTAVEKWNEKKEAFFKQKEKEKINEKRK 584
++E+ R E+E ER K+ +KE+E EK++ EK E+++ K+KE EK EK++
Sbjct: 503 EIRERER-EKEREREKELEKEQEQEREKER------EKDRERQQE--KEKELEKEQEKQR 553
Query: 585 E-----------ELKRAEKKDKDKQAINEYEKWLENKEKQERIERKQKKRHSFLE 628
E EL+R ++K+K+ Q + E EK E ++++E++E K + R LE
Sbjct: 554 EMEKERKQEKEKELERQKEKEKELQKMKEQEKECELEKEREKLEEKIEPREPNLE 608
Score = 48.1 bits (113), Expect = 2e-05
Identities = 81/405 (20%), Positives = 163/405 (40%), Gaps = 53/405 (13%)
Query: 231 ENLDPEDSCLTSLASSSLKQILGDSFSPGSEGNASGKDPNEEITENHNSLKSDENKENSF 290
+NLD E A + ++ + + + P E +E+ S K+ EN EN
Sbjct: 309 DNLDAEAD--EGWAGAQMEVDYTEQLNFSDDDEQGSNSPKENNSEDQGS-KASENNENKK 365
Query: 291 SADHVTTAVEKSK-ESQVTADDLEEEKAKAELIMDDDRTVDPLLSKSQSILISTSATAS- 348
D V+ S+ +Q + + K + + +R L +L
Sbjct: 366 ETDEVSNTKSSSQIPAQPSVAKVPYGKGPS---FNQERGTSSHLPPPPKLLAQQHPPPDR 422
Query: 349 -----------SKKTI--EDRNIKNKKSTNNRASSA--SARLMTSEFLKKSSSKRRTPST 393
SK+ + ED K ++ + S+A AR E ++ +R+
Sbjct: 423 QAVPGRPGPFPSKQQVADEDEIWKQRRRQQSEISAAVERARKRREEEERRMEEQRKAACA 482
Query: 394 TTSSHYLGTLKVLDQKPSQKQSIEPDRADNIRAAVYQEWLEKKNVYLHEMHRIKRIESEN 453
L +L+++PS ++ E +R + ++ LEK+ E R K E +
Sbjct: 483 EKLKRLDEKLGILEKQPSPEEIRERERE---KEREREKELEKEQ----EQEREKEREKDR 535
Query: 454 LRIQNEQKKAAKREEALASFEAW-KAMKEKEAKKIAAKKRLEEKNKKKTEEENAARKGEA 512
R Q ++K+ K +E E K KEKE ++ K++ +K K++ +E ++ E
Sbjct: 536 ERQQEKEKELEKEQEKQREMEKERKQEKEKELERQKEKEKELQKMKEQEKECELEKEREK 595
Query: 513 LQAFEKWKEKKMEYLKEKNRKEREYERAKK-----------QKEEETVAEKKKDNLTAVE 561
L+ + +E +E + EK E + ++ +KE V + T E
Sbjct: 596 LEEKIEPREPNLEPMVEKQESENSCNKEEEPVFTRQDSNRSEKEATPVVHE-----TEPE 650
Query: 562 KWNEKKEA----FFKQKEKE--KINEKRKEELKRAEKKDKDKQAI 600
++ + A +FKQ +K ++++E++K+ + + + +Q +
Sbjct: 651 SGSQPRPAVLSGYFKQFQKSLPPRFQRQQEQMKQQQWQQQQQQGV 695
Score = 34.3 bits (77), Expect = 0.37
Identities = 51/262 (19%), Positives = 108/262 (41%), Gaps = 32/262 (12%)
Query: 390 TPSTTTSSHYLGTLKVLDQKP-SQKQSIEPD------RADNIRA---AVYQEWLEKKNVY 439
TP T + + LDQ+ + S+E + +AD IR A Q++L +
Sbjct: 822 TPKATEEPEDVRSEAALDQEQITAAYSVEHNQLEAHPKADFIRESSEAQVQKFLSRSVED 881
Query: 440 LHEMHRIKRIESENLRIQNEQKKAAKREEALASFEAWKAMKEKEAKKIAAKKRLEEKNKK 499
+ H +S +++ +A +EE +++ E+ + K + ++ +K +
Sbjct: 882 VRPHHTDANNQSACFEAPDQKTLSAPQEERISAVESQPSRK----RSVSHGSNHTQKPDE 937
Query: 500 KTEEENAARKGEALQAFEKWKEKKMEYLKEKNRKEREYERAKKQKEEETVAEKKKDNLTA 559
+ E +A + + ++ +E +EK +KE ++ K E+ K +
Sbjct: 938 QRSEPSAGIPKVTSRCIDS--KEPIERPEEKPKKEGFIRSSEGPKPEKVYKSKSET---- 991
Query: 560 VEKWNEKKEAFFKQKEKEKINEK---RKEELKRAEKKDKDKQAINEYEKWLENKEKQERI 616
+W + + +E++N++ R +K+ +D ++ EK EK E++
Sbjct: 992 --RWGPRPSS----NRREEVNDRPVRRSGPIKKPVLRDMKEEREQRKEK---EGEKAEKV 1042
Query: 617 ERKQKKRHSFLESEALPPWSPP 638
K + E + LPP PP
Sbjct: 1043 TEKVVVKPEKTEKKDLPPPPPP 1064
>gi|239745127 PREDICTED: similar to Putative golgin subfamily A
member 6-like protein 6 [Homo sapiens]
Length = 655
Score = 68.9 bits (167), Expect = 1e-11
Identities = 88/429 (20%), Positives = 193/429 (44%), Gaps = 33/429 (7%)
Query: 227 KAFSENLDPEDSCLTSLASSSLKQI---LGDSFSPGSEGNASGKDPNEEITENHNSLKSD 283
K + E+ D E+S + SLK++ L D + G + K ++E+ + +
Sbjct: 82 KRWDEDDDLEESEDSKQCKESLKRVTFTLPDDEAIEDAGVSHVKKNSDEVKSSFKKRQEK 141
Query: 284 ENKENSFSADHVTTAVEKSKESQVTADDLEEEKAKAELIMDDDRT-----VDPLLSKSQS 338
N++N V + +VTA E E + D ++ L + +
Sbjct: 142 MNEKNYTFRKRVVIKKPWLRLGEVTAQKRPENSLLEETLHFDHAVRMGTYIEKLTKERDA 201
Query: 339 ILISTSATASSKKTIEDRNIKNKKSTNNRASSASARLMTSEFLKKSSSKRRT----PSTT 394
+ + + + ++++N + ++ S S + + LK+ + +
Sbjct: 202 LSLELYRNTITDEELKEKNAELQEKLRLVESEKSEIQLNVKDLKRKLERAQLLLPQQQLQ 261
Query: 395 TSSHYLGTLKVLDQKPSQKQS-IEPDRADNIRAAVYQEWLEKKNVYLHEMHRIKRIESEN 453
+ LG K L ++ Q+ +E + N+ +E + ++ + E K E E
Sbjct: 262 VEADRLG--KELQSVSAKLQAQVEENELWNLLNQQQEEKMWRQEEKIQEQEE-KMCEQE- 317
Query: 454 LRIQNEQKKAAKREEALASFEAWKAMKEKEAKKIAAKKRLEEKNKK-KTEEENAARKGEA 512
L+I+ +++K ++EE + E + ++E+E K ++++ E+ +K + +EE R+ E
Sbjct: 318 LKIREQEEKMWRQEEKMHEQE--EKIREQEDKMWRQEEKIREQEEKIREQEEKMWRQEEK 375
Query: 513 L---------QAFEKWKEKKMEYLKEKNRKEREYERAKKQKE-EETVAEKKKDNLTAVEK 562
+ Q E W++++ +E+ R+E+ + + KK +E +E + E++++ EK
Sbjct: 376 IREQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEK 435
Query: 563 WNEKKEAFFKQKEK-EKINEKRKEELKRAEKKDKDKQAINEYEKWLENKEKQERIERKQK 621
E +E Q+EK ++ EK +EE ++ +++++ Q + EK E +EK R E+ K
Sbjct: 436 IRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQ--RQEEKIQEQEEKTWRQEKLLK 493
Query: 622 KRHSFLESE 630
+ E E
Sbjct: 494 QEEKIWEQE 502
Score = 66.6 bits (161), Expect = 7e-11
Identities = 69/363 (19%), Positives = 157/363 (43%), Gaps = 34/363 (9%)
Query: 278 NSLKSDENKENSFSADHVTTAVEKSK-ESQVTADDLEEEKAKAELIMDDDRT---VDPLL 333
N++ +E KE + VE K E Q+ DL+ + +A+L++ + D L
Sbjct: 209 NTITDEELKEKNAELQEKLRLVESEKSEIQLNVKDLKRKLERAQLLLPQQQLQVEADRLG 268
Query: 334 SKSQSILISTSATASSKKTIEDRNIKNKKST---NNRASSASARLMTSEFLKKSSSKRRT 390
+ QS+ A + N + ++ + ++ E + ++
Sbjct: 269 KELQSVSAKLQAQVEENELWNLLNQQQEEKMWRQEEKIQEQEEKMCEQELKIREQEEKMW 328
Query: 391 PSTTTSSHYLGTLKVLDQKPSQKQSIEPDRADNIRAAVYQEWLEKKNVYLHEMHRIKRIE 450
++ + K +++ ++ + IR + W +++ +I
Sbjct: 329 RQEEKMHEQEEKIREQEDKMWRQEEKIREQEEKIREQEEKMWRQEE-----------KIR 377
Query: 451 SENLRIQNEQKKAAKREEALASFEAWKAMKEKEAKKIAAKKRLEEKNKKKTEEENAARKG 510
++ +IQ ++++ ++EE + E K +E KK E+ K + +EE R+
Sbjct: 378 EQDEKIQEQEEEMWRQEEKIREQEE----KRQEKMWRQEKKMREQDEKIREQEEEMWRQE 433
Query: 511 EALQAFEKW---KEKKMEYLKEKNRKERE---YERAKKQKEEETVAEKKKDN------LT 558
E ++ E+ +E+K+ ++EK ++E E + K Q++EE + E+++ L
Sbjct: 434 EKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKLLK 493
Query: 559 AVEKWNEKKEAFFKQKEKEKINEKRKEELKRAEKKDKDKQAINEYEKWLENKEKQERIER 618
EK E++E ++Q+EK E++ +E + ++ ++K E W + ++ QE+ R
Sbjct: 494 QEEKIWEQEEKMWRQEEKMWEQEEKMQEQEEKMQRQEEKMREQEVRLWQQEEKMQEQEVR 553
Query: 619 KQK 621
Q+
Sbjct: 554 LQE 556
Score = 66.2 bits (160), Expect = 9e-11
Identities = 55/245 (22%), Positives = 127/245 (51%), Gaps = 22/245 (8%)
Query: 407 DQKPSQKQSIEPDRADNIRAAVYQEWLEKKNVYLHEMHRIKRIESENLRIQNEQKKAAKR 466
++K +++ ++ IR + W +++ ++ E ++I + ++ +++K ++
Sbjct: 303 EEKIQEQEEKMCEQELKIREQEEKMWRQEEKMHEQE----EKIREQEDKMWRQEEKIREQ 358
Query: 467 EEALASFEAWKAMKEKEAKKIAAKKRLEEKNKKKTEEENAARKGEALQAFEKWK-EKKME 525
EE + E + M +E K ++++E+ ++ +E R+ E + + W+ EKKM
Sbjct: 359 EEKIREQE--EKMWRQEEKIREQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMR 416
Query: 526 YLKEKNRKERE--YERAKKQKEEETVAEKKKDNLTAVE-KWNEKKEAFFKQKEK-----E 577
EK R++ E + + +K +E E + + +++ L VE K E++E +Q+EK E
Sbjct: 417 EQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEE 476
Query: 578 KINEK-----RKEELKRAEKK--DKDKQAINEYEKWLENKEKQERIERKQKKRHSFLESE 630
KI E+ R+E+L + E+K +++++ + EK E +EK + E K +++ + +
Sbjct: 477 KIQEQEEKTWRQEKLLKQEEKIWEQEEKMWRQEEKMWEQEEKMQEQEEKMQRQEEKMREQ 536
Query: 631 ALPPW 635
+ W
Sbjct: 537 EVRLW 541
Score = 58.9 bits (141), Expect = 1e-08
Identities = 91/478 (19%), Positives = 195/478 (40%), Gaps = 60/478 (12%)
Query: 123 DIVVKSFSESQNKDEE----FEKDKIKMKPKPRILSIKSTSSAENNSLDTDDHFKPSPRP 178
D V SF + Q K E F K + KP R+ + + EN+ L+ HF + R
Sbjct: 129 DEVKSSFKKRQEKMNEKNYTFRKRVVIKKPWLRLGEVTAQKRPENSLLEETLHFDHAVRM 188
Query: 179 RSMLKKKSHMEEKDGLEDKETALSEELELHSAPSSLPTPNGIQLEAEKKAFSENLDPEDS 238
+ ++K + + LE +++E EL + L + +E+EK N+
Sbjct: 189 GTYIEKLTKERDALSLELYRNTITDE-ELKEKNAELQEKLRL-VESEKSEIQLNVKDLKR 246
Query: 239 CLTS---LASSSLKQILGDSFSPGSEGNASGKDPNEEITENHNSLKSDENKENSFSADHV 295
L L Q+ D + ++ E E N L + ++ + +
Sbjct: 247 KLERAQLLLPQQQLQVEADRLGKELQSVSAKLQAQVEENELWNLLNQQQEEKMWRQEEKI 306
Query: 296 TTAVEKSKESQVTADDLEEEKAKAELIMDDDRTVDPLLSKSQSILISTSATASSKKTIED 355
EK E ++ + EE+ + E M + +K E
Sbjct: 307 QEQEEKMCEQELKIREQEEKMWRQEEKMHE----------------------QEEKIREQ 344
Query: 356 RNIKNKKSTNNRASSASARLMTSEFLKKSSSKRRTPSTTTSSHYLGTLKVLDQKPSQKQS 415
+ ++ R R + ++ R D+K +++
Sbjct: 345 EDKMWRQEEKIREQEEKIREQEEKMWRQEEKIREQ----------------DEKIQEQEE 388
Query: 416 IEPDRADNIRAAVYQEWLEKKNVYLHEMHRIKRIESENLRIQNEQKKAAKREEALASFEA 475
+ + IR QE ++ ++ E K++ ++ +I+ ++++ ++EE + E
Sbjct: 389 EMWRQEEKIRE---QEEKRQEKMWRQE----KKMREQDEKIREQEEEMWRQEEKIRELEE 441
Query: 476 WKAMKEKEAKKIAAKKRLEEKNKKKTEEENAARKGEALQAFEK--WKEKKMEYLKEK--N 531
+E++ +++ K + EE+ K + +EE R+ E +Q E+ W+++K+ +EK
Sbjct: 442 MMQDQEEKLREVEEKMQ-EEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQEEKIWE 500
Query: 532 RKEREYERAKKQ-KEEETVAEKKKDNLTAVEKWNEKKEAFFKQKEKEKINEKRKEELK 588
++E+ + + +K ++EE + E+++ EK E++ ++Q+EK + E R +EL+
Sbjct: 501 QEEKMWRQEEKMWEQEEKMQEQEEKMQRQEEKMREQEVRLWQQEEKMQEQEVRLQELE 558
>gi|87299628 biorientation of chromosomes in cell division 1-like
[Homo sapiens]
Length = 3051
Score = 68.6 bits (166), Expect = 2e-11
Identities = 100/507 (19%), Positives = 205/507 (40%), Gaps = 71/507 (14%)
Query: 163 NNSLDTDDHFKPSPRPRSMLKKKSHMEEKDGLEDKETALSEELELHSAPSS------LPT 216
+ SL T P P S +E L + +A E +A +S LP+
Sbjct: 180 DTSLITQGVPTPGPSANVANDAMSILETITSLNQEASAARASTETSNAKTSERASKKLPS 239
Query: 217 PNGIQLEAEKKAFSENLDPEDSCLTSLASSSLKQILGDSFSPGSEGNASGKDPNEEI--- 273
+K+ SE++ ++ L+ +P SE + P EEI
Sbjct: 240 QPTTDTSTDKERTSEDMADKEKSTADSGGEGLET------APKSEEFSDLPCPVEEIKNY 293
Query: 274 TENHNSL---KSDENKENSFSADHVTTAVEKSKESQVTADDLEEEKAKAELIMDDDRTVD 330
T+ HN+L D +E+S + T EK +S + +E+K K E D +
Sbjct: 294 TKEHNNLILLNKDVQQESSEQKNKSTDKGEKKPDSNEKGERKKEKKEKTEKKFDHSK--- 350
Query: 331 PLLSKSQSILISTSATASSKKTIEDRNIKNKKSTNNRASSASARLMTSEFLKKSSSKRRT 390
KS+ + +K +E + ++K++N + + +F S
Sbjct: 351 ----KSEDTQKVKDEKQAKEKEVESLKLPSEKNSNKAKTVEGTK---EDFSLIDSDVDGL 403
Query: 391 PSTTTSSHYLGTLKVLDQKPSQKQSIEPDRADNIRAAVYQEWLEKKN------------- 437
T SS + L ++ ++++ + D + E K+N
Sbjct: 404 TDITVSSVHTSDLSSFEED-TEEEVVTSDSMEEGEITSDDEEKNKQNKTKTQTSDSSEGK 462
Query: 438 ------VYLHEMHRIKRIESENLRIQNEQKKAAKREEALASFEAWKAMKEKEAKKIAAKK 491
Y+H+ + + S++ +++ +R +++A K +E+ ++ ++
Sbjct: 463 TKSVRHAYVHKPYLYSKYYSDS----DDELTVEQRRQSIA-----KEKEERLLRRQINRE 513
Query: 492 RLEEKNKKKTEEENAAR-KGEALQAFEKWKEKKMEYLKEKNRKEREYERAKKQKEEETVA 550
+LEEK K+K E+ +++ KG+ + + +E + L+ K + +E + +K E++
Sbjct: 514 KLEEKRKQKAEKTKSSKTKGQGRSSVD-LEESSTKSLEPKAARIKEVLKERKVLEKKVAL 572
Query: 551 EKKKDNLTAVEKWNEKKEAFFKQKEKEKIN-----EKRK----EELKRAEKK---DKDKQ 598
KK+ + + N KK+ +++ KE + EK K +ELK K K +
Sbjct: 573 SKKRKKDSRNVEENSKKKQQYEEDSKETLKTSEHCEKEKISSSKELKHVHAKSEPSKPAR 632
Query: 599 AINEYEKWLENKEKQERIERKQKKRHS 625
++E ++ + + ++ER+ K+R S
Sbjct: 633 RLSESLHVVDENKNESKLEREHKRRTS 659
Score = 66.2 bits (160), Expect = 9e-11
Identities = 121/636 (19%), Positives = 242/636 (38%), Gaps = 91/636 (14%)
Query: 56 LGDFSDTSADENSVNKKMNDFHI-SDDEEKNPSKLLFLKTNKSNGNITKDEPVCAIKNE- 113
L F + + +E + M + I SDDEEKN +T+ S+ TK +
Sbjct: 416 LSSFEEDTEEEVVTSDSMEEGEITSDDEEKNKQNKTKTQTSDSSEGKTKSVRHAYVHKPY 475
Query: 114 --EEMAPDGCEDIVVKSFSESQNKDEE-------FEKDKIKMKPKPRILSIKS--TSSAE 162
+ D +++ V+ +S K++E ++K++ K K + KS T
Sbjct: 476 LYSKYYSDSDDELTVEQRRQSIAKEKEERLLRRQINREKLEEKRKQKAEKTKSSKTKGQG 535
Query: 163 NNSLDTDDHFKPSPRPRS-----MLKKKSHMEEKDGLEDKETALSEELELHSAPSSLPTP 217
+S+D ++ S P++ +LK++ +E+K L K S +E +S
Sbjct: 536 RSSVDLEESSTKSLEPKAARIKEVLKERKVLEKKVALSKKRKKDSRNVEENSKKKQ---- 591
Query: 218 NGIQLEAEKKAFSENLDPEDSCLTSLASSSLKQILGDSFSPGSEGNASGKDPNEEITENH 277
Q E + K E L + C SSS + + S S+ + + EN
Sbjct: 592 ---QYEEDSK---ETLKTSEHCEKEKISSSKELKHVHAKSEPSKPARRLSESLHVVDENK 645
Query: 278 NSLKSDENKENSFSADHVTTAVEKSKESQVTADDLEEEKAKAELIMDDDRTVDPLLSKSQ 337
N K + + S + V++ +++ D++ + ++E+ ++ + L +
Sbjct: 646 NESKLEREHKRRTSTPVIMEGVQEETDTR----DVKRQVERSEICTEEPQKQKSTLKNEK 701
Query: 338 SILISTSATASSKKTIEDRNIKNKKSTNNRASSASARLMTSEFLKKSSSKRRTPSTTTSS 397
+ S T K ++ + +K+ K R + S ++ + K +T T
Sbjct: 702 HLKKDDSETPHLKSLLK-KEVKSSKEKPEREKTPSEDKLSVKHKYKGDCMHKTGDETELH 760
Query: 398 HYLGTLKVLD--QKPSQKQSIEPDRADNIRAA---------------VYQEWLEK--KNV 438
LKV + QK SQ+ + D ++ E++ K +NV
Sbjct: 761 SSEKGLKVEENIQKQSQQTKLSSDDKTERKSKHRNERKLSVLGKDGKPVSEYIIKTDENV 820
Query: 439 YLHEMHRIKRIESENLRIQNEQKKAAK---REEALASFEAWKAM---------------- 479
+ +R+ +E + +++ ++++ ++++L S + +
Sbjct: 821 RKENNKKERRLSAEKTKAEHKSRRSSDSKIQKDSLGSKQHGITLQRRSESYSEDKCDMDS 880
Query: 480 --------------KEKEAKKIAAKKRLEEKNKKKTEEENAARKGEALQAFEKWKEKKME 525
KEK K +++L K+K KT+ + LQ + +
Sbjct: 881 TNMDSNLKPEEVVHKEKRRTKSLLEEKLVLKSKSKTQGKQVKVVETELQEGATKQATTPK 940
Query: 526 YLKEKNRKEREYERAKKQKEEETVAEKKKDNLTAVEKWNEKKEAFFKQKEKEKINEKRKE 585
KEKN +E + E+ +K K E+ E+ T VE E + +K+ + +
Sbjct: 941 PDKEKNTEENDSEKQRKSKVEDKPFEE-----TGVEPVLETASSSAHSTQKDSSHRAKLP 995
Query: 586 ELKRAEKKDKDKQAINEYEKWLENKEKQERIERKQK 621
K K DKD + E+ L + K ++ K
Sbjct: 996 LAKEKYKSDKDSTS-TRLERKLSDGHKSRSLKHSSK 1030
Score = 51.2 bits (121), Expect = 3e-06
Identities = 103/530 (19%), Positives = 203/530 (38%), Gaps = 73/530 (13%)
Query: 127 KSFSESQNKDEEFEKD-KIKMKPKPRILSIKSTSSAENNSLDTDDHFKPSP-RPRSMLKK 184
++ E+ K +++E+D K +K K +SS E + H K P +P L +
Sbjct: 581 RNVEENSKKKQQYEEDSKETLKTSEHCEKEKISSSKELKHV----HAKSEPSKPARRLSE 636
Query: 185 KSHMEEKDGLEDKETALSEELELHSAPSSLPT-PNGIQLEAEKKAFSENLDPEDSCLTS- 242
H+ +++ E K L E H +S P G+Q E + + ++ + C
Sbjct: 637 SLHVVDENKNESK---LERE---HKRRTSTPVIMEGVQEETDTRDVKRQVERSEICTEEP 690
Query: 243 -LASSSLKQIL----GDSFSPG------SEGNASGKDPNEEITENHNSLK-SDENKENSF 290
S+LK DS +P E +S + P E T + + L + K +
Sbjct: 691 QKQKSTLKNEKHLKKDDSETPHLKSLLKKEVKSSKEKPEREKTPSEDKLSVKHKYKGDCM 750
Query: 291 SADHVTTAVEKSKESQVTADDLEEEKAKAELIMDD--DRTVDPLLSKSQSILISTSATAS 348
T + S++ ++++++ + +L DD +R + S+L S
Sbjct: 751 HKTGDETELHSSEKGLKVEENIQKQSQQTKLSSDDKTERKSKHRNERKLSVLGKDGKPVS 810
Query: 349 SKKTIEDRNIKNKKSTNNRASSASARLMTSEFLKKSSSKRRTPSTTTSSHYLGTLKVLDQ 408
D N++ + + R SA + + S SK + S + H + TL+
Sbjct: 811 EYIIKTDENVRKENNKKERRLSAEKTKAEHKSRRSSDSKIQKDSLGSKQHGI-TLQ---- 865
Query: 409 KPSQKQSIEPDRADNIRAAVYQEWLEKKNVYLHEMHRIKRIESENLRIQNEQKKAAKR-- 466
+ +S D+ D + + L+ + V E R K + E L ++++ K K+
Sbjct: 866 --RRSESYSEDKCD-MDSTNMDSNLKPEEVVHKEKRRTKSLLEEKLVLKSKSKTQGKQVK 922
Query: 467 -------EEALASFEAWKAMKEKEAKKIAAKKRLEEKNKKKTEEE--------------- 504
E A K KEK ++ ++K+ + K + K EE
Sbjct: 923 VVETELQEGATKQATTPKPDKEKNTEENDSEKQRKSKVEDKPFEETGVEPVLETASSSAH 982
Query: 505 ----NAARKGEALQAFEKWKEKKMEYLKEKNRKEREYERAK---------KQKEEETVAE 551
+++ + + A EK+K K RK + +++ K+K+E +
Sbjct: 983 STQKDSSHRAKLPLAKEKYKSDKDSTSTRLERKLSDGHKSRSLKHSSKDIKKKDENKSDD 1042
Query: 552 KKKDNLTAVEKWNEKKEAFFKQKEKEKINEKRKEELKRAEKKDKDKQAIN 601
K + + + + ++K ++ E R+ L + K ++K A N
Sbjct: 1043 KDGKEVDSSHEKARGNSSLMEKKLSRRLCENRRGSLSQEMAKGEEKLAAN 1092
Score = 43.9 bits (102), Expect = 5e-04
Identities = 79/419 (18%), Positives = 160/419 (38%), Gaps = 68/419 (16%)
Query: 274 TENHNSLKSDENKENSFSADHVTTAVEKSKESQVTADDLE----------EEKAKAELIM 323
TE N+ S+ + S T+ +K + S+ AD + E K+E
Sbjct: 222 TETSNAKTSERASKKLPSQPTTDTSTDKERTSEDMADKEKSTADSGGEGLETAPKSEEFS 281
Query: 324 DDDRTVDPL--LSKSQSILISTSATASSKKTIEDRNIKNKKSTNNRASSASARLMTSEFL 381
D V+ + +K + LI + + + + KNK + S +
Sbjct: 282 DLPCPVEEIKNYTKEHNNLILLNKDVQQESSEQ----KNKSTDKGEKKPDSNEKGERKKE 337
Query: 382 KKSSSKRRTPSTTTSSHYLGTLKVLDQKPSQKQSIE----PDRADNIRAAVYQEWLEKKN 437
KK ++++ + S T KV D+K ++++ +E P ++ +A + E +
Sbjct: 338 KKEKTEKKFDHSKKSED---TQKVKDEKQAKEKEVESLKLPSEKNSNKAKTVEGTKEDFS 394
Query: 438 VYLHEMHRIKRIESENLRIQNEQKKAAKREEALASFEAWKAMKEKEAKKIAAKKRLEEKN 497
+ ++ + I ++ + EE + + ++ M+E E +K + K
Sbjct: 395 LIDSDVDGLTDITVSSVHTSDLSSFEEDTEEEVVTSDS---MEEGEITSDDEEKNKQNKT 451
Query: 498 KKKTEEENAARKGEALQAF------------EKWKEKKMEYLKEKNRKEREYERAKKQKE 545
K +T + + + A+ + E +E ++ KE+E ++Q
Sbjct: 452 KTQTSDSSEGKTKSVRHAYVHKPYLYSKYYSDSDDELTVEQRRQSIAKEKEERLLRRQIN 511
Query: 546 EETVAEKKKDNLTAVE-------------------KWNEKKEAFFKQKEKEK-------- 578
E + EK+K + K E K A K+ KE+
Sbjct: 512 REKLEEKRKQKAEKTKSSKTKGQGRSSVDLEESSTKSLEPKAARIKEVLKERKVLEKKVA 571
Query: 579 INEKRKEELKRAEKKDKDKQAINEYEK-WLENKE--KQERIERKQKKRHSFLESEALPP 634
+++KRK++ + E+ K KQ E K L+ E ++E+I ++ +H +SE P
Sbjct: 572 LSKKRKKDSRNVEENSKKKQQYEEDSKETLKTSEHCEKEKISSSKELKHVHAKSEPSKP 630
Score = 38.5 bits (88), Expect = 0.019
Identities = 62/303 (20%), Positives = 112/303 (36%), Gaps = 22/303 (7%)
Query: 134 NKDEEFEKDKIKMKPKPRILSIKSTSSA-----ENNSLDTD------DHFKPSPRPRSML 182
+KD + + K+ + S+K +S EN S D D H K M
Sbjct: 1004 DKDSTSTRLERKLSDGHKSRSLKHSSKDIKKKDENKSDDKDGKEVDSSHEKARGNSSLME 1063
Query: 183 KKKSHM--EEKDGLEDKETALSEELELHSAPSSLPTPNGIQLEAEKKAFSENLDPEDSCL 240
KK S E + G +E A EE A ++L TP+G L+ KK+ L PE +
Sbjct: 1064 KKLSRRLCENRRGSLSQEMAKGEE---KLAANTLSTPSGSSLQRPKKSGDMTLIPEQEPM 1120
Query: 241 TSLASSSLKQILGDSFSPGSEGNASGKDPNEEITENHNSLKSDENKENSFSADHVTTAVE 300
+ ++ + S + + N S +D + E + S +++ + +AD TA
Sbjct: 1121 EIDSEPGVENVFEVSKTQDNRNNNSQQDIDSENMKQKTSATVQKDELRTCTADSKATAPA 1180
Query: 301 KSKESQVTADDLEEEKAKAELIMDDDRTVDPLLSK-----SQSILISTSATASSKKTIED 355
+ E+ A + + +SK + I T+ +T+
Sbjct: 1181 YKPGRGTGVNSNSEKHADHRSTLTKKMHIQSAVSKMNPGEKEPIHRGTTEVNIDSETVH- 1239
Query: 356 RNIKNKKSTNNRASSASARLMTSEFLKKSSSKRRTPSTTTSSHYLGTLKVLDQKPSQKQS 415
R + + S N+R E + + + + SS L ++ V+ + S
Sbjct: 1240 RMLLSAPSENDRVQKNLKNTAAEEHVAQGDATLEHSTNLDSSPSLSSVTVVPLRESYDPD 1299
Query: 416 IEP 418
+ P
Sbjct: 1300 VIP 1302
Score = 31.2 bits (69), Expect = 3.1
Identities = 23/97 (23%), Positives = 47/97 (48%), Gaps = 2/97 (2%)
Query: 25 QDELIRAITARSAR-QRSSEYSDDFDSDEIVSLGDFSDTSADENSVNKKMNDFHISDDEE 83
+++++ ++ R + +RS SDD +S E S + E+ ++ +D ++EE
Sbjct: 2937 EEKIVTSVRRRGRKPKRSLTVSDDAESSEPERKRQKSVSDPVEDKKEQE-SDEEEEEEEE 2995
Query: 84 KNPSKLLFLKTNKSNGNITKDEPVCAIKNEEEMAPDG 120
PS T +S +K + +IK + E++P G
Sbjct: 2996 DEPSGATTRSTTRSEAQRSKTQLSPSIKRKREVSPPG 3032
>gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens]
Length = 2230
Score = 67.8 bits (164), Expect = 3e-11
Identities = 120/599 (20%), Positives = 237/599 (39%), Gaps = 70/599 (11%)
Query: 92 LKTNKSNGNITKDEPVCAIKNEE-------EMAPDGCEDIVVKSFSESQNKDEEFEKDKI 144
L + + +I +E KN+E + A + E + K + +E E +
Sbjct: 931 LSAKEDSIHILNEEYETKFKNQEKKMEKVKQKAKEMQETLKKKLLDQEAKLKKELENTAL 990
Query: 145 KMKPKPRILSIKSTSSAENNSLDTDDHFKPSPRPRSMLKKKSHMEEKDGLEDKETALSEE 204
++ K + + K A+ NS D S + ++ + E E + E
Sbjct: 991 ELSQKEKQFNAKMLEMAQANSAGISDAV--SRLETNQKEQIESLTEVHRRELNDVISIWE 1048
Query: 205 LELHSAPSSLPTPNGIQLEAEKKAFSENLDPEDSCLTSLASSSLKQILGDSFSPGSEGNA 264
+L+ L + IQL+ +++ +E + L + + + G + +
Sbjct: 1049 KKLNQQAEELQEIHEIQLQEKEQEVAEL--KQKILLFGCEKEEMNKEITWLKEEGVKQDT 1106
Query: 265 SGKDPNEEITENH---NSLKSDENKENSFSADHVTTAVEKSKESQVTADDLEEEKAKAEL 321
+ + E++ + NSL DE K + + KE+ + L E K AE
Sbjct: 1107 TLNELQEQLKQKSAHVNSLAQDETKLKAHLEKLEVDLNKSLKENTFLQEQLVELKMLAE- 1165
Query: 322 IMDDDRTVDPLLSK----SQSILISTSATASSKKTIEDRNIKNKKSTNNRA--------- 368
+D R V L SK + S+ S K++ED++++ KK + A
Sbjct: 1166 --EDKRKVSELTSKLKTTDEEFQSLKSSHEKSNKSLEDKSLEFKKLSEELAIQLDICCKK 1223
Query: 369 SSASARLMTSEFLKKSSSK-----------RRTPSTTTSSHYLGTLKVLDQKPSQKQSIE 417
+ A T+E + SSSK + + + + T V + + +Q E
Sbjct: 1224 TEALLEAKTNELINISSSKTNAILSRISHCQHRTTKVKEALLIKTCTVSELEAQLRQLTE 1283
Query: 418 PDRADNIRAAVYQEWLEKKNVYLHEMHR-IKRIESENLRIQ----NEQKKAAKREEALAS 472
NI LE+K + M I+ + +E +Q N+Q+ A+++E +
Sbjct: 1284 EQNTLNISFQQATHQLEEKENQIKSMKADIESLVTEKEALQKEGGNQQQAASEKESCITQ 1343
Query: 473 FEAW------------KAMKEKEAKKIAAKKRLEEKNKKKTEEENAARKGEALQAFEK-W 519
+ + +KEK+ + + K+L + N + + + K A+ + K +
Sbjct: 1344 LKKELSENINAVTLMKEELKEKKVEISSLSKQLTDLNVQLQNSISLSEKEAAISSLRKQY 1403
Query: 520 KEKKMEYLKEKNRKEREYERAKKQKEEETVAEKKKDNLTAVEKWNEKKEAFFKQKEKEKI 579
E+K E L + ++ ++ KE+ + E+ D +W +K ++ F Q +
Sbjct: 1404 DEEKCELLDQV--QDLSFKVDTLSKEKISALEQVDDWSNKFSEWKKKAQSRFTQHQNTVK 1461
Query: 580 NEKRKEELKRAEKKDKDKQAINEYEKWLENKEKQ--------ERIERKQKKRHSFLESE 630
+ + ELK E +KD+Q IN ++ L+ + K+ E + K +K+ S LE+E
Sbjct: 1462 ELQIQLELKSKEAYEKDEQ-INLLKEELDQQNKRFDCLKGEMEDDKSKMEKKESNLETE 1519
Score = 58.2 bits (139), Expect = 2e-08
Identities = 86/446 (19%), Positives = 183/446 (41%), Gaps = 52/446 (11%)
Query: 184 KKSHMEEKDGLEDKETALSEELELHSAPSSLPTPNGIQLEAEKKAFSENLDPEDSCLTSL 243
K HM EK L +++ + + L G+ + K+ E L+ ++ + L
Sbjct: 334 KDLHMAEKTKL------ITQLRDAKNLIEQLEQDKGMVIAETKRQMHETLEMKEEEIAQL 387
Query: 244 ASSSLKQILGDSFSPGSEGNASGKDPNEEITENHNSLKSDENKENSFSA--DHVTTAVEK 301
S +KQ+ + S + EE+ + ++ + E A D +EK
Sbjct: 388 RSR-IKQMTTQGEELREQKEKSERAAFEELEKALSTAQKTEEARRKLKAEMDEQIKTIEK 446
Query: 302 SKESQVTADDLEEEKAKAELIMDDDRTVDPLLSKSQSILISTSATASSKKTIEDRNIKNK 361
+ E + + E + K E++ ++ + ++K Q + A + T + ++ +
Sbjct: 447 TSEEERISLQQELSRVKQEVVDVMKKSSEEQIAKLQKLHEKELARKEQELT---KKLQTR 503
Query: 362 KSTNNRASSASARLMTSEFLKKSSSKRRTPSTTTSSHYLGTLKVLDQKPSQKQSIEPDRA 421
+ + SE+LK S K + S L++ QK++I +
Sbjct: 504 EREFQEQMKVALEKSQSEYLKISQEKEQQESLA-----------LEELELQKKAILTESE 552
Query: 422 DNIRAAVYQEWLEKKNVYLHEMHRIKRIESENLRIQNEQKKAAKREEALASFEAWKAMKE 481
+ +R + E +R + +E E+ ++ Q+ + ++ EA K
Sbjct: 553 NKLRDLQQEA----------ETYRTRILELESSLEKSLQENKNQSKDLAVHLEAEKNKHN 602
Query: 482 KEAKKIAAKKRLEEKNKKKTEEENAARKGEALQAFEKWKEKKMEYLKEKNRKEREYERAK 541
KE + K + E ++ K ++ A E LQ ++ + +ME L+EK +E+E
Sbjct: 603 KEITVMVEKHKTELESLKHQQD---ALWTEKLQVLKQQYQTEMEKLREKCEQEKE----T 655
Query: 542 KQKEEETVAEKKKDNLTAVEKWNEK--KEAFFKQKEKEKINEKRKEELKRAEKKDKD--- 596
K++E + + +E+ NEK ++ KQ E E ++ + E LK K +++
Sbjct: 656 LLKDKEIIFQ------AHIEEMNEKTLEKLDVKQTELESLSSELSEVLKARHKLEEELSV 709
Query: 597 -KQAINEYEKWLENKEKQERIERKQK 621
K ++ ++ LE K +++ +Q+
Sbjct: 710 LKDQTDKMKQELEAKMDEQKNHHQQQ 735
Score = 50.4 bits (119), Expect = 5e-06
Identities = 106/511 (20%), Positives = 216/511 (42%), Gaps = 88/511 (17%)
Query: 182 LKKKSHMEEKDGLEDKETALSEELELHSAPSSLPTPNGIQLEAEKKAFSENLDPEDSCLT 241
L++K E++ L+DKE +E E +K E LD + + L
Sbjct: 645 LREKCEQEKETLLKDKEIIFQAHIE----------------EMNEKTL-EKLDVKQTELE 687
Query: 242 SLASSSLKQILGDSFSPGSEGNASGKDPNEEITENHNSLKSDENKEN------SFSADHV 295
SL SS L ++L E + KD +++ + + K DE K + S +H
Sbjct: 688 SL-SSELSEVLKARHKLEEELSVL-KDQTDKMKQELEA-KMDEQKNHHQQQVDSIIKEHE 744
Query: 296 TTA--VEKSKESQVTADDL---------EEEKAKAELIMDDDRTVDPLLSKSQSIL---- 340
+ EK+ + Q+ +L +E +A E + D + + L ++ + L
Sbjct: 745 VSIQRTEKALKDQINQLELLLKERDKHLKEHQAHVENLEADIKRSEGELQQASAKLDVFQ 804
Query: 341 ISTSATASSKKTIEDRNIKNKKSTNNRASSASARLMTSEFLKKSSSKRRTPSTTTSSHYL 400
SAT K E++ + ++ + + R++ ++ + + ++++ T +H +
Sbjct: 805 SYQSATHEQTKAYEEQLAQLQQKLLDLETE---RILLTKQVAEVEAQKKDVCTELDAHKI 861
Query: 401 GTLKVLDQKPSQKQSIEPDRADNIRAAVYQEWLEKKNVYLHEMHRIKRIESENLRIQNEQ 460
++ Q +KQ+ E ++ VY+ LE N + +I +E EN+ +Q +
Sbjct: 862 QVQDLMQQL--EKQNSEMEQKVKSLTQVYESKLEDGNKEQEQTKQIL-VEKENMILQMRE 918
Query: 461 ----------KKAAKREEAL----ASFEAWKAMKEKEAKKIAAK-KRLEEKNKKKTEEEN 505
+K + +E+++ +E +EK+ +K+ K K ++E KKK ++
Sbjct: 919 GQKKEIEILTQKLSAKEDSIHILNEEYETKFKNQEKKMEKVKQKAKEMQETLKKKLLDQE 978
Query: 506 AARKGE----ALQAFEKWKEKKMEYLK----------------EKNRKEREYERAKKQKE 545
A K E AL+ +K K+ + L+ E N+KE+ + +
Sbjct: 979 AKLKKELENTALELSQKEKQFNAKMLEMAQANSAGISDAVSRLETNQKEQIESLTEVHRR 1038
Query: 546 E--ETVAEKKKDNLTAVEKWNEKKEAFFKQKEKEKINEKRKEELKRAEKKDKDKQAINEY 603
E + ++ +K E+ E E ++KE+E K+K L EK++ +K+
Sbjct: 1039 ELNDVISIWEKKLNQQAEELQEIHEIQLQEKEQEVAELKQKILLFGCEKEEMNKEITWLK 1098
Query: 604 EKWLEN----KEKQERIERKQKKRHSFLESE 630
E+ ++ E QE++++K +S + E
Sbjct: 1099 EEGVKQDTTLNELQEQLKQKSAHVNSLAQDE 1129
Score = 45.8 bits (107), Expect = 1e-04
Identities = 101/540 (18%), Positives = 199/540 (36%), Gaps = 60/540 (11%)
Query: 122 EDIVVKSFSESQNKDEEFEKDKIKMKPKPRILS-----IKSTSSAENNSLDTDDHFKPSP 176
E+ V +E + K +E E + +K K L ++S S+A+ L K +
Sbjct: 1591 ENQVYSMKAELETKKKELEHVNLSVKSKEEELKALEDRLESESAAKLAELKRKAEQKIAA 1650
Query: 177 RPRSMLKKKSHMEEK------DGLEDKETALSE-ELELHSAPSSLPTPNGIQLEA----- 224
+ +L + EE+ L + T L E E E+H L + Q E
Sbjct: 1651 IKKQLLSQMEEKEEQYKKGTESHLSELNTKLQEREREVHILEEKLKSVESSQSETLIVPR 1710
Query: 225 ---EKKAFSENLDPEDSCLTSLASSSLKQILGDSFSPGSEGNASGKDPNEEITENHNSLK 281
A++E + + +L + + + EE +H ++
Sbjct: 1711 SAKNVAAYTEQEEADSQGCVQKTYEEKISVLQRNLTEKEKLLQRVGQEKEETVSSHFEMR 1770
Query: 282 SDENKENSFSADHVTTAVEKSKESQVTADDLEEEKAKAELIMDDDRTVDPLLSKSQSILI 341
+ +E +H A K E Q L+EE + +K S+++
Sbjct: 1771 C-QYQERLIKLEH---AEAKQHEDQSMIGHLQEELEEK--------------NKKYSLIV 1812
Query: 342 STSATASSKKTIEDRNIKNKKSTNNRASSASARL----MTSEFLKKSSSKRRTPSTTTSS 397
+ K NI+ K++ N L +T + L++ + +
Sbjct: 1813 AQHVEKEGGKN----NIQAKQNLENVFDDVQKTLQEKELTCQILEQKIKELDSCLVRQKE 1868
Query: 398 HYLGTLKVLDQKPSQKQSIEPDRADNIRAAVYQEWLEKKNVYLHEMHRIKRIESENLRIQ 457
+ ++ L K + Q+++ N + +E E+K+ + H ++ N+ Q
Sbjct: 1869 VHRVEMEELTSKYEKLQALQQMDGRNKPTELLEENTEEKS----KSHLVQPKLLSNMEAQ 1924
Query: 458 NEQKK----AAKREEALASFEAWKAMKEKEAKKIAAKKRLEEKNKKKTEEENAARKGEAL 513
+ + A+RE+ E + K+ + ++ LE K+ +E K E
Sbjct: 1925 HNDLEFKLAGAEREKQKLGKEIVRLQKDLRMLRKEHQQELEILKKEYDQEREEKIKQEQE 1984
Query: 514 QAFEKWKEKKMEYLKEKNRKEREYERAKKQKEEETVAEKKKDNLTAVEKWNEKKEAFFKQ 573
K + ++E N + + E+ + +ET+ + ++ +E E+ K
Sbjct: 1985 DLELKHNSTLKQLMREFNTQLAQKEQELEMTIKETINKAQEVEAELLESHQEETNQLLK- 2043
Query: 574 KEKEKINEKRKEELKRAEKKDKDKQAINEYEKWLENKEKQERIERKQKKRHSFLESEALP 633
KI EK ++LKR K+ ++ E E + ++ Q ++E QKK LE E P
Sbjct: 2044 ----KIAEK-DDDLKRTAKRYEEILDAREEEMTAKVRDLQTQLEELQKKYQQKLEQEENP 2098
Score = 43.5 bits (101), Expect = 6e-04
Identities = 90/479 (18%), Positives = 177/479 (36%), Gaps = 74/479 (15%)
Query: 191 KDGLEDKETALSEELELHSAPSSLPTPNGIQLEAEKKAFSENLDPEDSCLTSLASSSLKQ 250
K + +++ L + L A S+ TP ++ + +F+E LD S + S Q
Sbjct: 6 KQKISEEQQQLQQALAPAQASSNSSTPT--RMRSRTSSFTEQLDEGTPNRESGDTQSFAQ 63
Query: 251 ILGDSFSPGSEGNASGKDPNEEITENHNSLKSDENKENSFSADHVTTAVEKSKESQVTAD 310
L + P+ E SL KE+ F + + V S +
Sbjct: 64 KL------------QLRVPSVE------SLFRSPIKESLFRSSSKESLVRTSSRESLNRL 105
Query: 311 DLEEEKAKAELIMDDDRTVDPLLSKSQS--------------------------ILISTS 344
DL+ A + D D + L+ S S ++ +
Sbjct: 106 DLDSSTASFDPPSDMDSEAEDLVGNSDSLNKEQLIQRLRRMERSLSSYRGKYSELVTAYQ 165
Query: 345 ATASSKKTIEDRNIKNKKSTNNRASSASARLMTSEFLKKSSSKRRTPSTTTSSHYLGTLK 404
KK ++ +++ + R + L + KK + S Y+ L+
Sbjct: 166 MLQREKKKLQGILSQSQDKSLRRIAELREELQMDQQAKKHLQEEFDASLEEKDQYISVLQ 225
Query: 405 VLDQKPSQKQSIEPDRADNIRAAVYQE-----WLEKKN------VYLHEMHRIKRIESEN 453
Q+ P D ++ E + +++N + + +K +E+
Sbjct: 226 TQVSLLKQRLRNGPMNVDVLKPLPQLEPQAEVFTKEENPESDGEPVVEDGTSVKTLETLQ 285
Query: 454 LRIQNEQKKAAKREEALASFEAWKAM--KEKEAKKIAAKKRLEEKNKKK-----TEEENA 506
R++ ++ + +E + S + + EKEA + +RL+E K K + +
Sbjct: 286 QRVKRQENLLKRCKETIQSHKEQCTLLTSEKEALQEQLDERLQELEKIKDLHMAEKTKLI 345
Query: 507 ARKGEALQAFEKWKEKKMEYLKEKNRKEREYERAKKQKEEETVAEKKKDNLTAVEKWNEK 566
+ +A E+ ++ K + E R+ E K++E + + K T E+ E+
Sbjct: 346 TQLRDAKNLIEQLEQDKGMVIAETKRQMHE-TLEMKEEEIAQLRSRIKQMTTQGEELREQ 404
Query: 567 KE----AFFKQKEKEKINEKRKEELKRAEKKDKDKQAINEYEKWLENKEKQERIERKQK 621
KE A F++ EK ++ EE +R K + D+Q K +E ++ERI +Q+
Sbjct: 405 KEKSERAAFEELEKALSTAQKTEEARRKLKAEMDEQI-----KTIEKTSEEERISLQQE 458
Score = 43.5 bits (101), Expect = 6e-04
Identities = 44/189 (23%), Positives = 88/189 (46%), Gaps = 18/189 (9%)
Query: 445 RIKRIE--SENLRIQNEQKKAAKREEALASFEAWKAMKEKEAKKIAAKKRLEEKNKKKTE 502
+IK IE SE RI +Q+ + ++E + MK+ ++IA ++L EK + E
Sbjct: 440 QIKTIEKTSEEERISLQQELSRVKQEVV------DVMKKSSEEQIAKLQKLHEKELARKE 493
Query: 503 EENAARKGEALQAFEKWKEKKMEYLKEKNRKEREYERAKKQKEEETVAEKKKDNLTAVEK 562
+E + LQ E+ +++M+ EK++ E +K+++E E+ + A+
Sbjct: 494 QELTKK----LQTREREFQEQMKVALEKSQSEYLKISQEKEQQESLALEELELQKKAILT 549
Query: 563 WNEKKEAFFKQKEKE------KINEKRKEELKRAEKKDKDKQAINEYEKWLENKEKQERI 616
+E K +Q+ + ++ ++ L+ + + KD E EK NKE +
Sbjct: 550 ESENKLRDLQQEAETYRTRILELESSLEKSLQENKNQSKDLAVHLEAEKNKHNKEITVMV 609
Query: 617 ERKQKKRHS 625
E+ + + S
Sbjct: 610 EKHKTELES 618
Score = 40.8 bits (94), Expect = 0.004
Identities = 65/325 (20%), Positives = 129/325 (39%), Gaps = 66/325 (20%)
Query: 272 EITENHNSLKSDENKENSFSADHVTTAVEKSKESQVTADDLEEEKAKAELIMDDDRTVDP 331
E+ +N+N K E+KE V+K + Q ++ + +AE +
Sbjct: 1546 EVLKNYNQQKDIEHKE----------LVQKLQHFQELGEEKDNRVKEAE---------EK 1586
Query: 332 LLSKSQSILISTSATASSKKTIEDRNIKNKKSTNNRASSASARLMTSEFLKKSSSKRRTP 391
+L+ + + + KK +E N+ + KS + RL + K + KR+
Sbjct: 1587 ILTLENQVYSMKAELETKKKELEHVNL-SVKSKEEELKALEDRLESESAAKLAELKRKAE 1645
Query: 392 STTTSSHYLGTLKVLDQKPSQKQSIEPDRADNIRAAVYQEWLEKKNVYLHEMHRIKRIES 451
+ + Q SQ + E +++ + +L E+
Sbjct: 1646 QKIAA--------IKKQLLSQMEEKE------------EQYKKGTESHLSEL-------- 1677
Query: 452 ENLRIQNEQKKAAKREEALASFEAWKA---MKEKEAKKIAAKKRLEEKNKKKTEEENAAR 508
N ++Q +++ EE L S E+ ++ + + AK +AA TE+E A
Sbjct: 1678 -NTKLQEREREVHILEEKLKSVESSQSETLIVPRSAKNVAAY----------TEQEEADS 1726
Query: 509 KGEALQAFEKWKEKKMEYLKEKNRKEREYERAKKQKEEETVAEKKKDNLTAVEKWNEKKE 568
+G +K E+K+ L+ ++ + + Q++EETV+ + E+ + +
Sbjct: 1727 QG----CVQKTYEEKISVLQRNLTEKEKLLQRVGQEKEETVSSHFEMRCQYQERLIKLEH 1782
Query: 569 AFFKQKEKEKINEKRKEELKRAEKK 593
A KQ E + + +EEL+ KK
Sbjct: 1783 AEAKQHEDQSMIGHLQEELEEKNKK 1807
>gi|95147555 microtubule-associated protein 1A [Homo sapiens]
Length = 2803
Score = 67.4 bits (163), Expect = 4e-11
Identities = 58/251 (23%), Positives = 126/251 (50%), Gaps = 33/251 (13%)
Query: 411 SQKQSIEPDRADNI-----RAAVYQEWLEKKNVYLHEMHRIKRIESENLRIQN------- 458
+ +Q EP+ D + + ++E +E K+ +++ +++E ++ Q+
Sbjct: 1353 TSEQKKEPEPKDEVLQQKDKTLEHKEVVEPKDTAIYQKDEALHVKNEAVKQQDKALEQKG 1412
Query: 459 ---EQKKAAKREEALASFEAWKAMKEKEAKKIAAKKRLEEKNKKKTEEENAA--RKGEAL 513
EQK A ++ A K ++EK+ K + K ++ E+ K E+++ A +K +AL
Sbjct: 1413 RDLEQKDTALEQKDKALEPKDKDLEEKD-KALEQKDKIPEEKDKALEQKDTALEQKDKAL 1471
Query: 514 QAFEKWKEKKMEYLKEKNRKEREYERAKKQK--------EEETVAEKKKDNLTAVEKWNE 565
+ +K E+K L++K + E ++A QK E+TVAE K +L +K E
Sbjct: 1472 EPKDKDLEQKDRVLEQKEKIPEEKDKALDQKVRSVEHKAPEDTVAEMKDRDLEQTDKAPE 1531
Query: 566 KKEAFFKQKEKEKINEKRKEELKR-----AEKKDKDKQAINEYEKWLENKEKQERIERKQ 620
+K Q++K+K++EK+ + L++ +K + +Q I E+ + +E++ ++ +
Sbjct: 1532 QKHQ--AQEQKDKVSEKKDQALEQKYWALGQKDEALEQNIQALEENHQTQEQESLVQEDK 1589
Query: 621 KKRHSFLESEA 631
++ LE ++
Sbjct: 1590 TRKPKMLEEKS 1600
Score = 53.1 bits (126), Expect = 8e-07
Identities = 49/194 (25%), Positives = 93/194 (47%), Gaps = 9/194 (4%)
Query: 450 ESENLRIQNEQKKAAKREEALASFEAWKAMKEKEAKKIAAKKRLEEKNKKKTEEENAARK 509
ES + K AKREE + E K + + AK++A ++ +++ +K E+ A +
Sbjct: 321 ESLKATTKTAVSKLAKREEVVE--EGAKEARSELAKELAKTEKKAKESSEKPPEKPAKPE 378
Query: 510 GEALQAFEKWKEKKMEYLKEKNRKEREYERAKKQKEEETVAEKKKDNLTAVEKWNEKKEA 569
++ E K +K + +K+K K+ E+ K +E++ +K+K + K +K E
Sbjct: 379 RVKTESSEALKAEKRKLIKDKVGKKHLKEKISKLEEKK---DKEKKEIKKERKELKKDEG 435
Query: 570 FFKQKEKEKINEKRKE---ELKRAEKKDKDKQAINEYEKWLENKEKQERIERKQKKRHSF 626
++K+ K EKRK+ ELK+ K D K E K L + R++ + +
Sbjct: 436 RKEEKKDAKKEEKRKDTKPELKKISKPDL-KPFTPEVRKTLYKAKVPGRVKIDRSRAIRG 494
Query: 627 LESEALPPWSPPSR 640
+ + P +PP++
Sbjct: 495 EKELSSEPQTPPAQ 508
Score = 50.8 bits (120), Expect = 4e-06
Identities = 103/515 (20%), Positives = 207/515 (40%), Gaps = 64/515 (12%)
Query: 153 LSIKSTSSAENNSLDTDDHFKPSPRPRSMLK------KKSHMEEKDGLEDKE--TALSEE 204
LS+ S ++ SLD + SP L+ K M ED TA
Sbjct: 1197 LSLSEESPSKETSLDVSSK-QLSPESLGTLQFGELNLGKEEMGHLMQAEDTSHHTAPMSV 1255
Query: 205 LELHSAPSSLPTPNGIQLEAEKKAFSENLD---PEDSCLTSLASSSLKQILGDSFSPGSE 261
E H+A +S PT + A+ ++LD P S S S + K + G SP
Sbjct: 1256 PEPHAATASPPTDGTTRYSAQTDITDDSLDRKSPASSFSHSTPSGNGKYLPGAITSPDEH 1315
Query: 262 GNASGKDPNEEITENHNSLKSDENKENSFS-ADHVTTAVEKSKESQVTADDLEEEKAKAE 320
P+ +++ SL ++ + D V +++ E + + +E + +
Sbjct: 1316 ILT----PDSSFSKSPESLPGPALEDIAIKWEDKVPGLKDRTSEQKKEPEPKDEVLQQKD 1371
Query: 321 LIMDDDRTVDP----LLSKSQSILISTSATASSKKTIEDRNIK-NKKSTNNRASSASARL 375
++ V+P + K +++ + A K +E + +K T +
Sbjct: 1372 KTLEHKEVVEPKDTAIYQKDEALHVKNEAVKQQDKALEQKGRDLEQKDTALEQKDKALEP 1431
Query: 376 MTSEFLKKSSSKRRTPSTTTSSHYLGTLKVLDQKPS----QKQSIEPDRADNIRAAVYQE 431
+ +K + + K L+QK + + +++EP D
Sbjct: 1432 KDKDLEEKDKALEQKDKIPEEKD-----KALEQKDTALEQKDKALEPKDKD--------- 1477
Query: 432 WLEKKNVYLHEMHRIKRIESENL--RIQNEQKKAAKREEALASFEAWKAMKEKEAKKIAA 489
LE+K+ L + +I + + L ++++ + KA E+ +A + E+ K
Sbjct: 1478 -LEQKDRVLEQKEKIPEEKDKALDQKVRSVEHKAP--EDTVAEMKDRDL--EQTDKAPEQ 1532
Query: 490 KKRLEEKNKKKTEEENAA--RKGEALQAFEKWKEKKMEYLKEKNRKEREYE---RAKKQK 544
K + +E+ K +E+++ A +K AL ++ E+ ++ L+E N + +E E + K +
Sbjct: 1533 KHQAQEQKDKVSEKKDQALEQKYWALGQKDEALEQNIQALEE-NHQTQEQESLVQEDKTR 1591
Query: 545 EEETVAEKKKDNLTAVEKWNEKKEAFFKQKEKEKINEKRKEELKRAEKKDKDKQAINEYE 604
+ + + EK + + A+E EK EA ++ + + E +E + E+++K + + +
Sbjct: 1592 KPKMLEEKSPEKVKAME---EKLEALLEKTKALGLEESLVQEGRAREQEEKYWRGQDVVQ 1648
Query: 605 KWLENKEKQERIERKQKKRHSFLESEALPPWSPPS 639
+W E +E +QK E P W S
Sbjct: 1649 EWQETSPTREEPAGEQK--------ELAPAWEDTS 1675
Score = 47.4 bits (111), Expect = 4e-05
Identities = 45/186 (24%), Positives = 82/186 (44%), Gaps = 19/186 (10%)
Query: 462 KAAKREEALASFEAWKAMKEKEAKKIAAKKRLEEKNKKKTEEENAARKGEALQAFEKWKE 521
K +K ++ S E+ KA + K+A ++ + E+ K+ E A + K ++
Sbjct: 309 KPSKIKQRADSKESLKATTKTAVSKLAKREEVVEEGAKEARSELA-------KELAKTEK 361
Query: 522 KKMEYLKEKNRKEREYERAKKQKEEETVAEKKKDNLTAVEKWNEKKEAFFKQKEKEKIN- 580
K E ++ K + ER K + E AEK+K K+ K+ KEKI+
Sbjct: 362 KAKESSEKPPEKPAKPERVKTESSEALKAEKRK----------LIKDKVGKKHLKEKISK 411
Query: 581 -EKRKEELKRAEKKDKDKQAINEYEKWLENKEKQERIERKQKKRHSFLESEALPPWSPPS 639
E++K++ K+ KK++ + +E K + K+E + K + L P++P
Sbjct: 412 LEEKKDKEKKEIKKERKELKKDEGRKEEKKDAKKEEKRKDTKPELKKISKPDLKPFTPEV 471
Query: 640 RTVFAK 645
R K
Sbjct: 472 RKTLYK 477
Score = 45.1 bits (105), Expect = 2e-04
Identities = 47/221 (21%), Positives = 97/221 (43%), Gaps = 28/221 (12%)
Query: 381 LKKSSSKRRTPSTTTSSHYLGTLKVLDQKPSQKQSIEPDRADNIRAAVYQEWL--EKKNV 438
LK S K+R S + T K K ++++ + + A R+ + +E EKK
Sbjct: 308 LKPSKIKQRADSKESLK---ATTKTAVSKLAKREEVVEEGAKEARSELAKELAKTEKKAK 364
Query: 439 YLHEMHRIKRIESENLRIQNEQKKAAKREEALASFEAWKAMKEKEAKKIAAKKRLEEKNK 498
E K + E ++ ++ + A++ + + K +KEK +K LEEK
Sbjct: 365 ESSEKPPEKPAKPERVKTESSEALKAEKRKLIKDKVGKKHLKEKISK-------LEEKKD 417
Query: 499 KKTEEENAARKGEALQAFEKWKEKKMEYLKEKNRKEREYERAKKQKEEETVAEKKKDNLT 558
K+ +E K+++ E K++ RKE + + K++K ++T E KK +
Sbjct: 418 KEKKE---------------IKKERKELKKDEGRKEEKKDAKKEEKRKDTKPELKKISKP 462
Query: 559 AVEKWN-EKKEAFFKQKEKEKINEKRKEELKRAEKKDKDKQ 598
++ + E ++ +K K ++ R ++ ++ + Q
Sbjct: 463 DLKPFTPEVRKTLYKAKVPGRVKIDRSRAIRGEKELSSEPQ 503
Score = 35.0 bits (79), Expect = 0.22
Identities = 25/110 (22%), Positives = 55/110 (50%), Gaps = 2/110 (1%)
Query: 518 KWKEKKMEYLKEKNRKEREYER-AKKQKEEETVAEKKKDNLTAVEKWNEKKEAFFKQKEK 576
K KE E +E+ K+R + A+ ++E++T EKK+ + E +E + ++
Sbjct: 591 KEKELVPEVPEEQGSKDRGLDSGAETEEEKDTWEEKKQREAERLPDRTEAREESEPEVKE 650
Query: 577 EKINEKRKEELKRAEKKDKDKQAINEYEKWLENKEKQERIERKQKKRHSF 626
+ I + EE++ D++++ + E + + K QE ++ + R +F
Sbjct: 651 DVIEKAELEEMEEVHPSDEEEEDATKAEGFYQ-KHMQEPLKVTPRSREAF 699
Score = 35.0 bits (79), Expect = 0.22
Identities = 48/271 (17%), Positives = 115/271 (42%), Gaps = 34/271 (12%)
Query: 103 KDEPVCAIKNEEEMAPDGCEDIVVKSFSESQNKDEEFEKDKIKMKPKPRILSIKSTSSAE 162
KDE + +KNE D + + + + KD E+ ++PK + L K + +
Sbjct: 1390 KDEAL-HVKNEAVKQQDKALE---QKGRDLEQKDTALEQKDKALEPKDKDLEEKDKALEQ 1445
Query: 163 NNSLDTDDHFKPSPRPRSMLKKKSHMEEKD-GLEDKETALSEELELHSAPSSLPTPNGIQ 221
+ + P + +++ +K + +E+KD LE K+ L ++ + +P
Sbjct: 1446 KDKI-------PEEKDKALEQKDTALEQKDKALEPKDKDLEQKDRVLEQKEKIPEEKDKA 1498
Query: 222 LEAEKKAFSENLDPEDSCLTSLASSSLKQILGDSFSPGSEGNASGKDPNEEITENHNSLK 281
L+ +K E+ PED+ + + L+Q E ++ ++++E K
Sbjct: 1499 LD-QKVRSVEHKAPEDT-VAEMKDRDLEQT-----DKAPEQKHQAQEQKDKVSE-----K 1546
Query: 282 SDENKENSFSA--------DHVTTAVEKSKESQVTADDLEEEKAKAELIMDD--DRTVDP 331
D+ E + A + A+E++ ++Q ++E+K + ++++ V
Sbjct: 1547 KDQALEQKYWALGQKDEALEQNIQALEENHQTQEQESLVQEDKTRKPKMLEEKSPEKVKA 1606
Query: 332 LLSKSQSILISTSATASSKKTIEDRNIKNKK 362
+ K +++L T A + +++ + ++
Sbjct: 1607 MEEKLEALLEKTKALGLEESLVQEGRAREQE 1637
Score = 31.2 bits (69), Expect = 3.1
Identities = 121/599 (20%), Positives = 220/599 (36%), Gaps = 112/599 (18%)
Query: 78 ISDD--EEKNPSKLLFLKTNKSNGNI------TKDEPVCA-----IKNEEEMAPDGCEDI 124
I+DD + K+P+ T NG + DE + K+ E + EDI
Sbjct: 1279 ITDDSLDRKSPASSFSHSTPSGNGKYLPGAITSPDEHILTPDSSFSKSPESLPGPALEDI 1338
Query: 125 VVKSFSESQNKDEEFEKDKIKMKPKPRILSIKSTSSAENNSLDTDDHFKPSPRPRSMLKK 184
+K + + + K + +PK +L +K
Sbjct: 1339 AIKWEDKVPGLKDRTSEQKKEPEPKDEVLQ----------------------------QK 1370
Query: 185 KSHMEEKDGLEDKETALSEELELHSAPSSLPTPNGIQLEAEKKAFSENLDPEDSCLTSLA 244
+E K+ +E K+TA+ ++ E +L N + +K + D E
Sbjct: 1371 DKTLEHKEVVEPKDTAIYQKDE------ALHVKNEAVKQQDKALEQKGRDLEQK------ 1418
Query: 245 SSSLKQILGDSFSPGSEGNASGKDPNEEITENHNSLKSDENKENSFSADHVTTAVE-KSK 303
++L+Q + KD + E + K +E + + TA+E K K
Sbjct: 1419 DTALEQ---------KDKALEPKDKDLEEKDKALEQKDKIPEEKDKALEQKDTALEQKDK 1469
Query: 304 ESQVTADDLEEE----KAKAELIMDDDRTVDPLLSKSQSILISTSATASSKKTIEDRNIK 359
+ DLE++ + K ++ + D+ +D K +S+ K ED +
Sbjct: 1470 ALEPKDKDLEQKDRVLEQKEKIPEEKDKALD---QKVRSV---------EHKAPEDTVAE 1517
Query: 360 NKKSTNNRASSASARLMTSEFLKKSSSKRRTPSTTTSSHYLGTL-KVLDQKPSQKQSIEP 418
K + A + ++ K S+++ + LG + L+Q Q++E
Sbjct: 1518 MKDRDLEQTDKAPEQKHQAQEQKDKVSEKKDQALEQKYWALGQKDEALEQ---NIQALEE 1574
Query: 419 DRADNIRAAVYQEWLEKKNVYLHEM--HRIKRIESENLRIQNEQKKAAKREEALASFEAW 476
+ + ++ QE +K L E ++K +E E L E+ KA EE+L +
Sbjct: 1575 NHQTQEQESLVQEDKTRKPKMLEEKSPEKVKAME-EKLEALLEKTKALGLEESLV--QEG 1631
Query: 477 KAMKEKEAKKIAAKKRLEEKNKKKTEEENAARKGEALQAFEKWKEKKMEYLKEKNRKERE 536
+A +++E E + T EE A GE + W++ E + NR R
Sbjct: 1632 RAREQEEKYWRGQDVVQEWQETSPTREEPA---GEQKELAPAWEDTSPE---QDNRYWRG 1685
Query: 537 YERAKKQKE---EETVAEKK------KDNLTAVEKWNEKKEAFFKQKEKEKINE-KRKEE 586
E +++ E E+K D A + E++E+ F + + E +E
Sbjct: 1686 REDVALEQDTYWRELSCERKVWFPHELDGQGARPHYTEERESTFLDEGPDDEQEVPLREH 1745
Query: 587 LKRA-------EKKDKDKQAINEYEKWLENKEKQERIERKQKKRHSFLESEALPPWSPP 638
R+ + ++ Q E E+WL E + K S E + PP SPP
Sbjct: 1746 ATRSPWASDFKDFQESSPQKGLEVERWLAESPVGLPPEEEDKLTRSPFEIIS-PPASPP 1803
Score = 30.4 bits (67), Expect = 5.3
Identities = 25/113 (22%), Positives = 45/113 (39%)
Query: 86 PSKLLFLKTNKSNGNITKDEPVCAIKNEEEMAPDGCEDIVVKSFSESQNKDEEFEKDKIK 145
PSK+ +K + T V + EE+ +G ++ + E +++ ++ K
Sbjct: 310 PSKIKQRADSKESLKATTKTAVSKLAKREEVVEEGAKEARSELAKELAKTEKKAKESSEK 369
Query: 146 MKPKPRILSIKSTSSAENNSLDTDDHFKPSPRPRSMLKKKSHMEEKDGLEDKE 198
KP T S+E + K + + +K S +EEK E KE
Sbjct: 370 PPEKPAKPERVKTESSEALKAEKRKLIKDKVGKKHLKEKISKLEEKKDKEKKE 422
>gi|239745153 PREDICTED: similar to Putative golgin subfamily A
member 6-like protein 6 [Homo sapiens]
Length = 655
Score = 67.0 bits (162), Expect = 5e-11
Identities = 88/429 (20%), Positives = 192/429 (44%), Gaps = 33/429 (7%)
Query: 227 KAFSENLDPEDSCLTSLASSSLKQI---LGDSFSPGSEGNASGKDPNEEITENHNSLKSD 283
K + E+ D E+S + SLK++ L D + G + K ++E+ + +
Sbjct: 82 KRWDEDDDLEESEDSKQCKESLKRVTFTLPDDEAIEDAGVSHVKKNSDEVKSSFKKRQEK 141
Query: 284 ENKENSFSADHVTTAVEKSKESQVTADDLEEEKAKAELIMDDDRT-----VDPLLSKSQS 338
N++N V + +VTA E E + D ++ L + +
Sbjct: 142 MNEKNYTFRKRVVIKKPWLRLGEVTAQKRPENSLLEETLHFDHAVRMGTYIEKLTKERDA 201
Query: 339 ILISTSATASSKKTIEDRNIKNKKSTNNRASSASARLMTSEFLKKSSSKRRT----PSTT 394
+ + + ++++N + ++ S S + + LK+ + +
Sbjct: 202 PSLELYRNTITDEELKEKNAELQEKLRLVESEKSEIQLNVKDLKRKLERAQLLLPQQQLQ 261
Query: 395 TSSHYLGTLKVLDQKPSQKQS-IEPDRADNIRAAVYQEWLEKKNVYLHEMHRIKRIESEN 453
+ LG K L ++ Q+ +E + N+ +E + ++ + E K E E
Sbjct: 262 VEADRLG--KELQSVSAKLQAQVEENELWNLLNQQQEEKMWRQEEKIQEQEE-KMCEQE- 317
Query: 454 LRIQNEQKKAAKREEALASFEAWKAMKEKEAKKIAAKKRLEEKNKK-KTEEENAARKGEA 512
L+I+ +++K ++EE + E + ++E+E K ++++ E+ +K + +EE R+ E
Sbjct: 318 LKIREQEEKMWRQEEKMHEQE--EKIREQEDKMWRQEEKIREQEEKIREQEEKMWRQEEK 375
Query: 513 L---------QAFEKWKEKKMEYLKEKNRKEREYERAKKQKE-EETVAEKKKDNLTAVEK 562
+ Q E W++++ +E+ R+E+ + + KK +E +E + E++++ EK
Sbjct: 376 IREQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEK 435
Query: 563 WNEKKEAFFKQKEK-EKINEKRKEELKRAEKKDKDKQAINEYEKWLENKEKQERIERKQK 621
E +E Q+EK ++ EK +EE ++ +++++ Q + EK E +EK R E+ K
Sbjct: 436 IRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQ--RQEEKIQEQEEKTWRQEKLLK 493
Query: 622 KRHSFLESE 630
+ E E
Sbjct: 494 QEEKIWEQE 502
Score = 66.6 bits (161), Expect = 7e-11
Identities = 69/363 (19%), Positives = 157/363 (43%), Gaps = 34/363 (9%)
Query: 278 NSLKSDENKENSFSADHVTTAVEKSK-ESQVTADDLEEEKAKAELIMDDDRT---VDPLL 333
N++ +E KE + VE K E Q+ DL+ + +A+L++ + D L
Sbjct: 209 NTITDEELKEKNAELQEKLRLVESEKSEIQLNVKDLKRKLERAQLLLPQQQLQVEADRLG 268
Query: 334 SKSQSILISTSATASSKKTIEDRNIKNKKST---NNRASSASARLMTSEFLKKSSSKRRT 390
+ QS+ A + N + ++ + ++ E + ++
Sbjct: 269 KELQSVSAKLQAQVEENELWNLLNQQQEEKMWRQEEKIQEQEEKMCEQELKIREQEEKMW 328
Query: 391 PSTTTSSHYLGTLKVLDQKPSQKQSIEPDRADNIRAAVYQEWLEKKNVYLHEMHRIKRIE 450
++ + K +++ ++ + IR + W +++ +I
Sbjct: 329 RQEEKMHEQEEKIREQEDKMWRQEEKIREQEEKIREQEEKMWRQEE-----------KIR 377
Query: 451 SENLRIQNEQKKAAKREEALASFEAWKAMKEKEAKKIAAKKRLEEKNKKKTEEENAARKG 510
++ +IQ ++++ ++EE + E K +E KK E+ K + +EE R+
Sbjct: 378 EQDEKIQEQEEEMWRQEEKIREQEE----KRQEKMWRQEKKMREQDEKIREQEEEMWRQE 433
Query: 511 EALQAFEKW---KEKKMEYLKEKNRKERE---YERAKKQKEEETVAEKKKDN------LT 558
E ++ E+ +E+K+ ++EK ++E E + K Q++EE + E+++ L
Sbjct: 434 EKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKLLK 493
Query: 559 AVEKWNEKKEAFFKQKEKEKINEKRKEELKRAEKKDKDKQAINEYEKWLENKEKQERIER 618
EK E++E ++Q+EK E++ +E + ++ ++K E W + ++ QE+ R
Sbjct: 494 QEEKIWEQEEKMWRQEEKMWEQEEKMQEQEEKMQRQEEKMREQEVRLWQQEEKMQEQEVR 553
Query: 619 KQK 621
Q+
Sbjct: 554 LQE 556
Score = 66.2 bits (160), Expect = 9e-11
Identities = 55/245 (22%), Positives = 127/245 (51%), Gaps = 22/245 (8%)
Query: 407 DQKPSQKQSIEPDRADNIRAAVYQEWLEKKNVYLHEMHRIKRIESENLRIQNEQKKAAKR 466
++K +++ ++ IR + W +++ ++ E ++I + ++ +++K ++
Sbjct: 303 EEKIQEQEEKMCEQELKIREQEEKMWRQEEKMHEQE----EKIREQEDKMWRQEEKIREQ 358
Query: 467 EEALASFEAWKAMKEKEAKKIAAKKRLEEKNKKKTEEENAARKGEALQAFEKWK-EKKME 525
EE + E + M +E K ++++E+ ++ +E R+ E + + W+ EKKM
Sbjct: 359 EEKIREQE--EKMWRQEEKIREQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMR 416
Query: 526 YLKEKNRKERE--YERAKKQKEEETVAEKKKDNLTAVE-KWNEKKEAFFKQKEK-----E 577
EK R++ E + + +K +E E + + +++ L VE K E++E +Q+EK E
Sbjct: 417 EQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEE 476
Query: 578 KINEK-----RKEELKRAEKK--DKDKQAINEYEKWLENKEKQERIERKQKKRHSFLESE 630
KI E+ R+E+L + E+K +++++ + EK E +EK + E K +++ + +
Sbjct: 477 KIQEQEEKTWRQEKLLKQEEKIWEQEEKMWRQEEKMWEQEEKMQEQEEKMQRQEEKMREQ 536
Query: 631 ALPPW 635
+ W
Sbjct: 537 EVRLW 541
Score = 60.1 bits (144), Expect = 6e-09
Identities = 91/478 (19%), Positives = 195/478 (40%), Gaps = 60/478 (12%)
Query: 123 DIVVKSFSESQNKDEE----FEKDKIKMKPKPRILSIKSTSSAENNSLDTDDHFKPSPRP 178
D V SF + Q K E F K + KP R+ + + EN+ L+ HF + R
Sbjct: 129 DEVKSSFKKRQEKMNEKNYTFRKRVVIKKPWLRLGEVTAQKRPENSLLEETLHFDHAVRM 188
Query: 179 RSMLKKKSHMEEKDGLEDKETALSEELELHSAPSSLPTPNGIQLEAEKKAFSENLDPEDS 238
+ ++K + + LE +++E EL + L + +E+EK N+
Sbjct: 189 GTYIEKLTKERDAPSLELYRNTITDE-ELKEKNAELQEKLRL-VESEKSEIQLNVKDLKR 246
Query: 239 CLTS---LASSSLKQILGDSFSPGSEGNASGKDPNEEITENHNSLKSDENKENSFSADHV 295
L L Q+ D + ++ E E N L + ++ + +
Sbjct: 247 KLERAQLLLPQQQLQVEADRLGKELQSVSAKLQAQVEENELWNLLNQQQEEKMWRQEEKI 306
Query: 296 TTAVEKSKESQVTADDLEEEKAKAELIMDDDRTVDPLLSKSQSILISTSATASSKKTIED 355
EK E ++ + EE+ + E M + +K E
Sbjct: 307 QEQEEKMCEQELKIREQEEKMWRQEEKMHE----------------------QEEKIREQ 344
Query: 356 RNIKNKKSTNNRASSASARLMTSEFLKKSSSKRRTPSTTTSSHYLGTLKVLDQKPSQKQS 415
+ ++ R R + ++ R D+K +++
Sbjct: 345 EDKMWRQEEKIREQEEKIREQEEKMWRQEEKIREQ----------------DEKIQEQEE 388
Query: 416 IEPDRADNIRAAVYQEWLEKKNVYLHEMHRIKRIESENLRIQNEQKKAAKREEALASFEA 475
+ + IR QE ++ ++ E K++ ++ +I+ ++++ ++EE + E
Sbjct: 389 EMWRQEEKIRE---QEEKRQEKMWRQE----KKMREQDEKIREQEEEMWRQEEKIRELEE 441
Query: 476 WKAMKEKEAKKIAAKKRLEEKNKKKTEEENAARKGEALQAFEK--WKEKKMEYLKEK--N 531
+E++ +++ K + EE+ K + +EE R+ E +Q E+ W+++K+ +EK
Sbjct: 442 MMQDQEEKLREVEEKMQ-EEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQEEKIWE 500
Query: 532 RKEREYERAKKQ-KEEETVAEKKKDNLTAVEKWNEKKEAFFKQKEKEKINEKRKEELK 588
++E+ + + +K ++EE + E+++ EK E++ ++Q+EK + E R +EL+
Sbjct: 501 QEEKMWRQEEKMWEQEEKMQEQEEKMQRQEEKMREQEVRLWQQEEKMQEQEVRLQELE 558
>gi|221219020 NYD-SP11 protein [Homo sapiens]
Length = 2873
Score = 66.6 bits (161), Expect = 7e-11
Identities = 124/602 (20%), Positives = 239/602 (39%), Gaps = 70/602 (11%)
Query: 65 DENSVNKKMNDFHISDDEE---KNPSKLLFLKTNKSNGNITKDEPVCAIKNEE----EMA 117
+E KK D ++ + K K++FL+ GN+T + + K EE + +
Sbjct: 1346 EEEQAQKKARDMLGLEETQVILKKGKKVIFLEP----GNVTMGKEIS--KKEEKKTFQKS 1399
Query: 118 PDGCEDIVVKS----------FSESQNKDEEFEK----DKIKMKPKPRILSIKSTSSAEN 163
P V K E ++ EE E+ ++ +K + +++ I+ T S ++
Sbjct: 1400 PKQGRKAVQKERKVGKIKREMTKEERDMSEEVEEMATLEEKVVKQEGKLVMIERTPSWQD 1459
Query: 164 NSLDTDDHFKPSPRPRSMLKKKSHMEEKDGLEDKETALSEELELHSAPSSLPTPNGIQLE 223
D+ + R K EK L EE +LH A L +P L+
Sbjct: 1460 WKKAWDEWKQVHGETRKSWKAWKEEWEK-------RLLQEEEKLHQAGEKL-SPEEEMLQ 1511
Query: 224 AEKKAFSENLDPEDSCLTSLASSSLKQILGDSFSPGSEGNASGKDPNEEITENHNSLKSD 283
+KK E + S S + + + E + G++ +++TE ++ +
Sbjct: 1512 EDKKLKWEEWKQVWENMLSSKSKEQQYKDEEEVTLEEEVSREGEEKEQQVTEEQRHIQ-E 1570
Query: 284 ENKENSFSADHVTTAVEKSKESQVTADDLEEEKAKAELIMDDDRTVDPLLSK----SQSI 339
E+K ++++E + A + E+ + + ++R + K + +
Sbjct: 1571 EHKWARIHRKRARAEKKRAQEERKLAQEEEKLAQEERQLAQEERKLAQAYVKITQDDREM 1630
Query: 340 LISTSATASSKKTIEDRNIKNKKSTNNRASSASARLMTSEFLKKSSSKRRTPSTTTSSHY 399
+ A ++T+ R K + A E + + K +
Sbjct: 1631 AQAEGKFAQKEETLAQRGEKLSQEAEKLAQKRKKLAKKWEKVAREEEKLAKKGGKLAEVK 1690
Query: 400 LGTLKVLDQKPSQKQSIEPDRADNIRAAVYQEWLEKKNVYLHEMHRIKRIESENLRIQNE 459
+ +++ P ++Q+++ + + EW ++ + E + E ++ E
Sbjct: 1691 NILAQKVEELPQREQNLDWQEKELAQELEELEWDMEELSWKEE-----ELNQEEGKLVEE 1745
Query: 460 QKKAAKREEALA------SFEAWKAMKEKEAKKIAAKKRLEEKNKKKTEEENAARKGEAL 513
+KK A+ EEALA S E K +E+E +K + K K EEE RK E L
Sbjct: 1746 KKKLAEEEEALAWQREKLSEEETKLAQEEELLIQEKEKLAQHKEKMPEEEERLGRKREQL 1805
Query: 514 QAFEKWKEKKMEYLKEKNRKEREYERAKKQK----EEETVAEKKKDNLTAVEKWNEKKEA 569
EKKM+ +++ R E K K +++ +A++KK NL ++KE
Sbjct: 1806 I------EKKMKLAQKRERWINSMEELTKNKMILYQKKNLAQEKK-NLA------QEKEK 1852
Query: 570 FFKQKEKEKINEKRKEELKRAEKKDKDKQAI-NEYEKWLENKEKQERIERKQKKRHSFLE 628
++KE N++R K+ + K+K + N+ +E K QE+ E KK+ E
Sbjct: 1853 LAQRKENLLYNKERLTHSKKQLVQVKNKLGMFNKILAQVEEKLTQEK-ETVIKKKEKLAE 1911
Query: 629 SE 630
+E
Sbjct: 1912 TE 1913
Score = 66.2 bits (160), Expect = 9e-11
Identities = 64/250 (25%), Positives = 125/250 (50%), Gaps = 35/250 (14%)
Query: 409 KPSQKQSIEPDRADNIRAAVYQEWLEKKNVYLHE--MHRIKR-IESENLRIQNEQKKAAK 465
K + S EP + + I A+ + +++ + E M ++KR + + R+ EQ K
Sbjct: 2061 KKRESLSKEPAKLNKILKALQKLTRDERKLTQEEIKMTKMKRALFVKERRLSIEQSKLDI 2120
Query: 466 REEALASFEAWKAMKEKEAKKIAAK--------KRLEEKNKKKTEEEN--AARKGEALQA 515
+E F ++ K+ KK+A K +R+ K +K TEEE+ A + E +
Sbjct: 2121 KEW---DFSEKRSELTKDEKKLARKQRKLANKMRRMINKEEKMTEEESKLARKHSEVILD 2177
Query: 516 FEKW----KEKKMEYLKEKNRKEREYERAKKQKE-----------EETVAEKKKDNLTAV 560
E+ +E+ + +LK + RK +E +R K KE EE +E+ + L +
Sbjct: 2178 DEEEGGIEEEEVIPFLKRRWRKRKEAKRGDKPKEKFSSQVDEVESEEHFSEEMESLLDEL 2237
Query: 561 EKWNEKKEAFFKQKEKEKINEKRKEELKRAEKKDKDKQAINEYEKWLENKEKQERIERKQ 620
EK +E+ ++E+E+ E+ +EE + E++++ K+ EK +E +E++++ ++K+
Sbjct: 2238 EK----QESLSSEEEEEREEEEEREEEEVREEEEERKEEEEGEEKQVEKEEEEKKKKKKE 2293
Query: 621 KKRHSFLESE 630
KK+ E E
Sbjct: 2294 KKKEEVQEKE 2303
Score = 61.6 bits (148), Expect = 2e-09
Identities = 109/527 (20%), Positives = 222/527 (42%), Gaps = 75/527 (14%)
Query: 105 EPVCAIKNEEEMAPDGCEDIVVKSFSESQNKDEEFEKDKIKMKPKPRILSIKSTSSAENN 164
E IK +E++A E +V+ K E+ ++K+K+ + ++ K E +
Sbjct: 1898 EKETVIKKKEKLAET--EKKLVQVEDSLAKKQEKLAQEKMKLALEKAMVQGKKRLRGELD 1955
Query: 165 SLDTDDHFKPSPRPRSMLKKKSHMEEKDGL-EDKETALSEELELHSAPSSLPTPNGIQLE 223
+ L+ K EEK L E KET E S + E
Sbjct: 1956 IAKEEKALN--------LEMKRLAEEKMRLVEGKETLSKGETPETSRQRKMTQVEQELFE 2007
Query: 224 AEKKAFSENLDPEDSCLTSLASSSLKQILGDSFSPGS----EGNASGKDPNEEITENHNS 279
+ + L ED L S K L F+ G +G + ++ + S
Sbjct: 2008 RKLSLEEKILLHEDRILAMEESEIAKGKL--EFTRGQRIFVQGQRKLAKASRKLIKKRES 2065
Query: 280 LKSDENKENSFSADHVTTAVEK--SKESQVTADDLEEEKAKAELIMDDDRTVDPLLSKSQ 337
L + K N + A++K E ++T ++++ K K L + + R LS Q
Sbjct: 2066 LSKEPAKLNK-----ILKALQKLTRDERKLTQEEIKMTKMKRALFVKERR-----LSIEQ 2115
Query: 338 SILISTSATASSKKTIEDRNIKNKKSTNNRASSASARLMTSE--FLKKSSSKRRTPSTTT 395
S L S K++ ++ K + ++ R++ E ++ S R S
Sbjct: 2116 SKLDIKEWDFSEKRSELTKDEKKLARKQRKLANKMRRMINKEEKMTEEESKLARKHSEV- 2174
Query: 396 SSHYLGTLKVLDQKPSQKQSIEPDRADNIRAAVYQEWLEKKNVYLHEMHRIKRIESENLR 455
+LD + ++ IE + + + + W ++K + + ++ S+
Sbjct: 2175 ---------ILDDE--EEGGIEEEE---VIPFLKRRWRKRKEAKRGDKPK-EKFSSQVDE 2219
Query: 456 IQNEQKKAAKREEALASFEAWKAMKEKEAKKIAAKKRLEEKNKKKTEEENAARKGEALQA 515
+++E+ + + E L E +++ +E ++ ++ EE+ +++ EE RK E
Sbjct: 2220 VESEEHFSEEMESLLDELEKQESLSSEEEEE---REEEEEREEEEVREEEEERKEE---- 2272
Query: 516 FEKWKEKKMEYLKEKNRKEREYERAKKQKEEETVAEKKKDNLTAVEKWNEKKEAFFKQKE 575
E+ +EK++E ++E E ++ KK+K++E V EK E+ E+KE ++E
Sbjct: 2273 -EEGEEKQVE------KEEEEKKKKKKEKKKEEVQEK--------EEVFEEKEEIMSEEE 2317
Query: 576 KEKINEKRKEELKRAEKKDKDKQAINEYEKWLENKEKQERIERKQKK 622
E ++++ +EE + +++ D+ EK + KEKQ +++ +++K
Sbjct: 2318 TESLSDEEEEEESCSLEEEVDR------EKEILKKEKQFKLQEQRRK 2358
Score = 60.1 bits (144), Expect = 6e-09
Identities = 48/199 (24%), Positives = 99/199 (49%), Gaps = 7/199 (3%)
Query: 435 KKNVYLHEMHRIKRIESENLRIQNEQKKAAKREEALASFEAWKAMKEKEA---KKIAAKK 491
K+ ++M R+ I E + E K A K E + E ++E+E K +K
Sbjct: 2142 KQRKLANKMRRM--INKEEKMTEEESKLARKHSEVILDDEEEGGIEEEEVIPFLKRRWRK 2199
Query: 492 RLEEKNKKKTEEENAARKGEALQAFEKWKEKKMEYLKEKNRKEREYERAKKQKEEETVAE 551
R E K K +E+ +++ E +++ E + E+ L E ++E ++++EEE E
Sbjct: 2200 RKEAKRGDKPKEKFSSQVDE-VESEEHFSEEMESLLDELEKQESLSSEEEEEREEEEERE 2258
Query: 552 KKKDNLTAVEKWNEKKEAFFKQKEKEKINEKRKEELKRAEKKDKDKQAINEYEKWLENKE 611
+++ E+ E++E KQ EKE+ +K+K++ K+ E+ + ++ E E+ + +E
Sbjct: 2259 EEEVREEEEER-KEEEEGEEKQVEKEEEEKKKKKKEKKKEEVQEKEEVFEEKEEIMSEEE 2317
Query: 612 KQERIERKQKKRHSFLESE 630
+ + ++++ LE E
Sbjct: 2318 TESLSDEEEEEESCSLEEE 2336
Score = 57.8 bits (138), Expect = 3e-08
Identities = 118/560 (21%), Positives = 229/560 (40%), Gaps = 62/560 (11%)
Query: 113 EEEMAPDGCEDIVVKSFSESQNKD------EEFEKDKIKMKPKPRILSIKSTSSAENNSL 166
EEE E ++ K +Q ++ EE K+K+ + K + K + E L
Sbjct: 1794 EEERLGRKREQLIEKKMKLAQKRERWINSMEELTKNKMILYQKKNLAQEKKNLAQEKEKL 1853
Query: 167 DTDDHFKPSPRPRSMLKKKSHMEEKD--GLEDKETALSEELELHSAPSSLPTPNGIQLEA 224
+ R KK ++ K+ G+ +K A EE +L ++ E
Sbjct: 1854 AQRKENLLYNKERLTHSKKQLVQVKNKLGMFNKILAQVEE-KLTQEKETVIKKKEKLAET 1912
Query: 225 EKKAFSENLDPEDSCLTS---LASSSLKQILGDSFSPGSEGNASGKD-PNEEITENHNSL 280
EKK + EDS LA +K L + G + D EE N
Sbjct: 1913 EKKL----VQVEDSLAKKQEKLAQEKMKLALEKAMVQGKKRLRGELDIAKEEKALNLEMK 1968
Query: 281 KSDENK------ENSFSADHVTTAVEKSKESQVTADDLEEEKAKAE-LIMDDDRTVDPLL 333
+ E K + + S + K +QV + E + + E +++ +DR +
Sbjct: 1969 RLAEEKMRLVEGKETLSKGETPETSRQRKMTQVEQELFERKLSLEEKILLHEDRILAMEE 2028
Query: 334 S----------KSQSILIS--TSATASSKKTIEDRNIKNKKSTN-NRASSASARL----- 375
S + Q I + +S+K I+ R +K+ N+ A +L
Sbjct: 2029 SEIAKGKLEFTRGQRIFVQGQRKLAKASRKLIKKRESLSKEPAKLNKILKALQKLTRDER 2088
Query: 376 -MTSEFLKKSSSKRRT-PSTTTSSHYLGTLKVLDQKPSQKQS-IEPDRADNIR-----AA 427
+T E +K + KR S L + + S+K+S + D R A
Sbjct: 2089 KLTQEEIKMTKMKRALFVKERRLSIEQSKLDIKEWDFSEKRSELTKDEKKLARKQRKLAN 2148
Query: 428 VYQEWLEKKNVYLHEMHRIKRIESENLRIQNEQKKAAKREEALASFEA-WKAMKEKEAKK 486
+ + K+ E ++ R SE + + +E++ + EE + + W+ KE +
Sbjct: 2149 KMRRMINKEEKMTEEESKLARKHSEVI-LDDEEEGGIEEEEVIPFLKRRWRKRKEAKRGD 2207
Query: 487 IAAKKRLEEKNKKKTEEENAARKGEALQAFEKWK----EKKMEYLKEKNRKEREYERAKK 542
+K + ++ ++EE + L EK + E++ E +E+ R+E E ++
Sbjct: 2208 KPKEKFSSQVDEVESEEHFSEEMESLLDELEKQESLSSEEEEEREEEEEREEEEVREEEE 2267
Query: 543 QKEEETVAEKKKDNLTAVEKWNEKKEAFFKQKEKEKINEKRKE-ELKRAEKKDKDKQAIN 601
+++EE E+K+ VEK E+K+ K+K+KE++ EK + E K +++ ++++
Sbjct: 2268 ERKEEEEGEEKQ-----VEKEEEEKKKKKKEKKKEEVQEKEEVFEEKEEIMSEEETESLS 2322
Query: 602 EYEKWLENKEKQERIERKQK 621
+ E+ E+ +E ++R+++
Sbjct: 2323 DEEEEEESCSLEEEVDREKE 2342
Score = 57.8 bits (138), Expect = 3e-08
Identities = 93/453 (20%), Positives = 188/453 (41%), Gaps = 70/453 (15%)
Query: 149 KPRILSIKSTSSAENNSLDTDDHFKPSPRPRSMLKKKSHMEEKDGLEDKETALSEELELH 208
K R++ K T S + + +T K + + + ++K +EEK L + EE E+
Sbjct: 1974 KMRLVEGKETLS-KGETPETSRQRKMTQVEQELFERKLSLEEKILLHEDRILAMEESEIA 2032
Query: 209 SAPSSLPTPNGIQLEAEKKAF--SENLDPEDSCLTSLASSSLKQILGDSFSPGSEGNASG 266
I ++ ++K S L + L S + L +IL A
Sbjct: 2033 KGKLEFTRGQRIFVQGQRKLAKASRKLIKKRESL-SKEPAKLNKIL----------KALQ 2081
Query: 267 KDPNEEITENHNSLKSDENKENSFSADHVTTAVEKSKESQVTADDLEEEKAKAELIMDDD 326
K +E +K + K F + ++E+SK + + + + ++EL D+
Sbjct: 2082 KLTRDERKLTQEEIKMTKMKRALFVKER-RLSIEQSK---LDIKEWDFSEKRSELTKDEK 2137
Query: 327 RTVDPLLSKSQSILISTSATASSKK---TIEDRNIKNKKSTNNRASSASARLMTSE---F 380
+ L++ Q L + +K+ T E+ + K S + E F
Sbjct: 2138 K-----LARKQRKLANKMRRMINKEEKMTEEESKLARKHSEVILDDEEEGGIEEEEVIPF 2192
Query: 381 LKKSSSKRRTPSTTTSSHYLGTLKVLDQKPSQKQSIEPDRADNIRAAVYQEWLEKKNVYL 440
LK+ KR+ KP +K S + D ++ + + E+ L
Sbjct: 2193 LKRRWRKRKEAKR-------------GDKPKEKFSSQVDEVES-----EEHFSEEMESLL 2234
Query: 441 HEMHRIKRIESENLRIQNEQKKAAKREEALASFEAWKAMKEKEAKKIAAKKRLEEKNKKK 500
E+ + + + SE + E+++ +REE E + +E+E ++ +K EEK KKK
Sbjct: 2235 DELEKQESLSSEE---EEEREEEEEREEEEVREEEEERKEEEEGEEKQVEKEEEEKKKKK 2291
Query: 501 TEEENAARKGEALQAFEKWKEKKMEYLKEKNRKEREYERAKKQKEEETVA-EKKKDNLTA 559
KEKK E ++EK E E ++E E+++ E++++ +
Sbjct: 2292 -------------------KEKKKEEVQEKEEVFEEKEEIMSEEETESLSDEEEEEESCS 2332
Query: 560 VEKWNEKKEAFFKQKEKEKINEKRKEELKRAEK 592
+E+ ++++ K++++ K+ E+R++ L+ E+
Sbjct: 2333 LEEEVDREKEILKKEKQFKLQEQRRKSLRGRER 2365
Score = 52.4 bits (124), Expect = 1e-06
Identities = 78/389 (20%), Positives = 158/389 (40%), Gaps = 51/389 (13%)
Query: 269 PNEEITENHNSLKSDENK---ENSFSADHVTTAVEKSKESQVTADDLEEEKAKAELIMDD 325
P EE+ + LK +E K EN S+ + +E + + E + K + + ++
Sbjct: 1505 PEEEMLQEDKKLKWEEWKQVWENMLSSKSKEQQYKDEEEVTLEEEVSREGEEKEQQVTEE 1564
Query: 326 DRTVDPLLSKSQSILISTSATASSKKTIEDRNI---KNKKSTNNRASSASARLMTSEFLK 382
R + + + A A K+ E+R + + K + R + R + ++K
Sbjct: 1565 QRHIQE--EHKWARIHRKRARAEKKRAQEERKLAQEEEKLAQEERQLAQEERKLAQAYVK 1622
Query: 383 KSSSKRRTPSTTTSSHYLGTLKVLDQKPSQKQSIEPDRADNIRAAVYQEWLEKKNVYLHE 442
+ R + K +QK+ R + + E L +K
Sbjct: 1623 ITQDDREMAQA-------------EGKFAQKEETLAQRGEKLSQEA--EKLAQKR----- 1662
Query: 443 MHRIKRIESENLRIQNEQKKAAKREEALASFEAWKAMKEKEAKK------IAAKKRLEEK 496
K++ + ++ E++K AK+ LA + A K +E + K+ +E
Sbjct: 1663 ----KKLAKKWEKVAREEEKLAKKGGKLAEVKNILAQKVEELPQREQNLDWQEKELAQEL 1718
Query: 497 NKKKTEEENAARKGEALQAFE-KWKEKKMEYLKEK-----NRKEREYERAKKQKEEETVA 550
+ + + E + K E L E K E+K + +E+ R++ E K +EEE +
Sbjct: 1719 EELEWDMEELSWKEEELNQEEGKLVEEKKKLAEEEEALAWQREKLSEEETKLAQEEELLI 1778
Query: 551 EKKKDNLTAVEKWNEKKEAFFKQKE-----KEKINEKRKEELKRAEKKDKDKQAINEYEK 605
++K+ EK E++E +++E K K+ +KR+ + E+ K+K + + +
Sbjct: 1779 QEKEKLAQHKEKMPEEEERLGRKREQLIEKKMKLAQKRERWINSMEELTKNKMILYQKKN 1838
Query: 606 WLENKEK--QERIERKQKKRHSFLESEAL 632
+ K+ QE+ + Q+K + E L
Sbjct: 1839 LAQEKKNLAQEKEKLAQRKENLLYNKERL 1867
Score = 51.2 bits (121), Expect = 3e-06
Identities = 63/327 (19%), Positives = 144/327 (44%), Gaps = 51/327 (15%)
Query: 295 VTTAVEKSKESQVTADDLEEEKAKAELIMDDDRTVDPLLSKSQSILISTSATASSKKTIE 354
VT V + KE ++ ++KA+ L +++ + + L K + ++ + K I
Sbjct: 1332 VTQEVIRHKEVMPREEEQAQKKARDMLGLEETQVI---LKKGKKVIFLEPGNVTMGKEIS 1388
Query: 355 DRNIKNKKSTNNRASSASARLMTSEFLKKSSSKRRTPSTTTSSHYLGTLKVLDQKPSQKQ 414
K +K T ++ + + E + T S + + L++K +++
Sbjct: 1389 K---KEEKKTFQKSPKQGRKAVQKERKVGKIKREMTKEERDMSEEVEEMATLEEKVVKQE 1445
Query: 415 S----IEPDRADNIRAAVYQEWLEKKNVYLHEMHRIKRIESENLRIQNEQKKAAKREEAL 470
IE R +Q+W K+ E ++ E +K+
Sbjct: 1446 GKLVMIE-------RTPSWQDW--------------KKAWDEWKQVHGETRKS------- 1477
Query: 471 ASFEAWKAMKEK-EAKKIAAKKRLEEKNKKKTEEENAARKGEALQAFEKWKEKKMEYLKE 529
WKA KE+ E + + +++L + +K + EE ++ + L+ +E+WK+ L
Sbjct: 1478 -----WKAWKEEWEKRLLQEEEKLHQAGEKLSPEEEMLQEDKKLK-WEEWKQVWENMLSS 1531
Query: 530 KNRKEREYERAKKQKEEETVA---EKKKDNLTAVEKWNEKKEAFFKQKEKEKINEKRKEE 586
K+ KE++Y+ ++ EE V+ E+K+ +T ++ +++ + + K EK++ +
Sbjct: 1532 KS-KEQQYKDEEEVTLEEEVSREGEEKEQQVTEEQRHIQEEHKWARIHRKRARAEKKRAQ 1590
Query: 587 LKRAEKKDKDKQAINEYEKWLENKEKQ 613
+R ++++K A + E+ L +E++
Sbjct: 1591 EERKLAQEEEKLA--QEERQLAQEERK 1615
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.303 0.120 0.315
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 24,168,449
Number of Sequences: 37866
Number of extensions: 1220226
Number of successful extensions: 28859
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 599
Number of HSP's successfully gapped in prelim test: 1275
Number of HSP's that attempted gapping in prelim test: 7164
Number of HSP's gapped (non-prelim): 8784
length of query: 647
length of database: 18,247,518
effective HSP length: 109
effective length of query: 538
effective length of database: 14,120,124
effective search space: 7596626712
effective search space used: 7596626712
T: 11
A: 40
X1: 17 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 43 (21.8 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.