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Search of human proteins with 88758603
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|88758603 protein interacting with C kinase 1 [Homo sapiens]
(415 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|88758603 protein interacting with C kinase 1 [Homo sapiens] 827 0.0
gi|88758600 protein interacting with C kinase 1 [Homo sapiens] 827 0.0
gi|7110697 protein interacting with C kinase 1 [Homo sapiens] 827 0.0
gi|6912602 ADP-ribosylation factor interacting protein 2 [Homo s... 63 6e-10
gi|71040094 ADP-ribosylation factor interacting protein 1 isofor... 62 1e-09
gi|71040092 ADP-ribosylation factor interacting protein 1 isofor... 62 1e-09
gi|7657210 ADP-ribosylation factor interacting protein 1 isoform... 62 1e-09
gi|148746189 multiple PDZ domain protein [Homo sapiens] 47 2e-05
gi|187607085 ligand of numb-protein X 1 isoform a [Homo sapiens] 47 2e-05
gi|187607071 ligand of numb-protein X 1 isoform b [Homo sapiens] 47 2e-05
gi|9507165 syntrophin, gamma 2 [Homo sapiens] 47 3e-05
gi|148833504 interleukin 16 isoform 2 [Homo sapiens] 47 4e-05
gi|27262655 interleukin 16 isoform 1 precursor [Homo sapiens] 47 4e-05
gi|218505835 membrane-associated guanylate kinase-related 3 iso... 44 2e-04
gi|155969695 membrane-associated guanylate kinase-related 3 iso... 44 2e-04
gi|90819237 myeloid/lymphoid or mixed-lineage leukemia (trithora... 44 3e-04
gi|90819233 myeloid/lymphoid or mixed-lineage leukemia (trithora... 44 3e-04
gi|90819231 myeloid/lymphoid or mixed-lineage leukemia (trithora... 44 3e-04
gi|27436957 membrane associated guanylate kinase, WW and PDZ dom... 44 3e-04
gi|21361831 partitioning-defective protein 3 homolog [Homo sapiens] 43 5e-04
gi|87196343 PDZ domain containing 2 [Homo sapiens] 43 5e-04
gi|9966877 golgi associated PDZ and coiled-coil motif containing... 42 0.001
gi|62868213 golgi associated PDZ and coiled-coil motif containin... 42 0.001
gi|18375648 protein tyrosine phosphatase, non-receptor type 13 i... 42 0.001
gi|9507163 syntrophin, gamma 1 [Homo sapiens] 42 0.001
gi|112382257 InaD-like [Homo sapiens] 41 0.002
gi|18375650 protein tyrosine phosphatase, non-receptor type 13 i... 40 0.003
gi|18375646 protein tyrosine phosphatase, non-receptor type 13 i... 40 0.003
gi|5453992 protein tyrosine phosphatase, non-receptor type 13 is... 40 0.003
gi|110346445 FERM and PDZ domain containing 2 like 1 isoform 4 [... 40 0.005
>gi|88758603 protein interacting with C kinase 1 [Homo sapiens]
Length = 415
Score = 827 bits (2137), Expect = 0.0
Identities = 415/415 (100%), Positives = 415/415 (100%)
Query: 1 MFADLDYDIEEDKLGIPTVPGKVTLQKDAQNLIGISIGGGAQYCPCLYIVQVFDNTPAAL 60
MFADLDYDIEEDKLGIPTVPGKVTLQKDAQNLIGISIGGGAQYCPCLYIVQVFDNTPAAL
Sbjct: 1 MFADLDYDIEEDKLGIPTVPGKVTLQKDAQNLIGISIGGGAQYCPCLYIVQVFDNTPAAL 60
Query: 61 DGTVAAGDEITGVNGRSIKGKTKVEVAKMIQEVKGEVTIHYNKLQADPKQGMSLDIVLKK 120
DGTVAAGDEITGVNGRSIKGKTKVEVAKMIQEVKGEVTIHYNKLQADPKQGMSLDIVLKK
Sbjct: 61 DGTVAAGDEITGVNGRSIKGKTKVEVAKMIQEVKGEVTIHYNKLQADPKQGMSLDIVLKK 120
Query: 121 VKHRLVENMSSGTADALGLSRAILCNDGLVKRLEELERTAELYKGMTEHTKNLLRAFYEL 180
VKHRLVENMSSGTADALGLSRAILCNDGLVKRLEELERTAELYKGMTEHTKNLLRAFYEL
Sbjct: 121 VKHRLVENMSSGTADALGLSRAILCNDGLVKRLEELERTAELYKGMTEHTKNLLRAFYEL 180
Query: 181 SQTHRAFGDVFSVIGVREPQPAASEAFVKFADAHRSIEKFGIRLLKTIKPMLTDLNTYLN 240
SQTHRAFGDVFSVIGVREPQPAASEAFVKFADAHRSIEKFGIRLLKTIKPMLTDLNTYLN
Sbjct: 181 SQTHRAFGDVFSVIGVREPQPAASEAFVKFADAHRSIEKFGIRLLKTIKPMLTDLNTYLN 240
Query: 241 KAIPDTRLTIKKYLDVKFEYLSYCLKVKEMDDEEYSCIALGEPLYRVSTGNYEYRLILRC 300
KAIPDTRLTIKKYLDVKFEYLSYCLKVKEMDDEEYSCIALGEPLYRVSTGNYEYRLILRC
Sbjct: 241 KAIPDTRLTIKKYLDVKFEYLSYCLKVKEMDDEEYSCIALGEPLYRVSTGNYEYRLILRC 300
Query: 301 RQEARARFSQMRKDVLEKMELLDQKHVQDIVFQLQRLVSTMSKYYNDCYAVLRDADVFPI 360
RQEARARFSQMRKDVLEKMELLDQKHVQDIVFQLQRLVSTMSKYYNDCYAVLRDADVFPI
Sbjct: 301 RQEARARFSQMRKDVLEKMELLDQKHVQDIVFQLQRLVSTMSKYYNDCYAVLRDADVFPI 360
Query: 361 EVDLAHTTLAYGLNQEEFTDGEEEEEEEDTAAGEPSRDTRGAAGPLDKGGSWCDS 415
EVDLAHTTLAYGLNQEEFTDGEEEEEEEDTAAGEPSRDTRGAAGPLDKGGSWCDS
Sbjct: 361 EVDLAHTTLAYGLNQEEFTDGEEEEEEEDTAAGEPSRDTRGAAGPLDKGGSWCDS 415
>gi|88758600 protein interacting with C kinase 1 [Homo sapiens]
Length = 415
Score = 827 bits (2137), Expect = 0.0
Identities = 415/415 (100%), Positives = 415/415 (100%)
Query: 1 MFADLDYDIEEDKLGIPTVPGKVTLQKDAQNLIGISIGGGAQYCPCLYIVQVFDNTPAAL 60
MFADLDYDIEEDKLGIPTVPGKVTLQKDAQNLIGISIGGGAQYCPCLYIVQVFDNTPAAL
Sbjct: 1 MFADLDYDIEEDKLGIPTVPGKVTLQKDAQNLIGISIGGGAQYCPCLYIVQVFDNTPAAL 60
Query: 61 DGTVAAGDEITGVNGRSIKGKTKVEVAKMIQEVKGEVTIHYNKLQADPKQGMSLDIVLKK 120
DGTVAAGDEITGVNGRSIKGKTKVEVAKMIQEVKGEVTIHYNKLQADPKQGMSLDIVLKK
Sbjct: 61 DGTVAAGDEITGVNGRSIKGKTKVEVAKMIQEVKGEVTIHYNKLQADPKQGMSLDIVLKK 120
Query: 121 VKHRLVENMSSGTADALGLSRAILCNDGLVKRLEELERTAELYKGMTEHTKNLLRAFYEL 180
VKHRLVENMSSGTADALGLSRAILCNDGLVKRLEELERTAELYKGMTEHTKNLLRAFYEL
Sbjct: 121 VKHRLVENMSSGTADALGLSRAILCNDGLVKRLEELERTAELYKGMTEHTKNLLRAFYEL 180
Query: 181 SQTHRAFGDVFSVIGVREPQPAASEAFVKFADAHRSIEKFGIRLLKTIKPMLTDLNTYLN 240
SQTHRAFGDVFSVIGVREPQPAASEAFVKFADAHRSIEKFGIRLLKTIKPMLTDLNTYLN
Sbjct: 181 SQTHRAFGDVFSVIGVREPQPAASEAFVKFADAHRSIEKFGIRLLKTIKPMLTDLNTYLN 240
Query: 241 KAIPDTRLTIKKYLDVKFEYLSYCLKVKEMDDEEYSCIALGEPLYRVSTGNYEYRLILRC 300
KAIPDTRLTIKKYLDVKFEYLSYCLKVKEMDDEEYSCIALGEPLYRVSTGNYEYRLILRC
Sbjct: 241 KAIPDTRLTIKKYLDVKFEYLSYCLKVKEMDDEEYSCIALGEPLYRVSTGNYEYRLILRC 300
Query: 301 RQEARARFSQMRKDVLEKMELLDQKHVQDIVFQLQRLVSTMSKYYNDCYAVLRDADVFPI 360
RQEARARFSQMRKDVLEKMELLDQKHVQDIVFQLQRLVSTMSKYYNDCYAVLRDADVFPI
Sbjct: 301 RQEARARFSQMRKDVLEKMELLDQKHVQDIVFQLQRLVSTMSKYYNDCYAVLRDADVFPI 360
Query: 361 EVDLAHTTLAYGLNQEEFTDGEEEEEEEDTAAGEPSRDTRGAAGPLDKGGSWCDS 415
EVDLAHTTLAYGLNQEEFTDGEEEEEEEDTAAGEPSRDTRGAAGPLDKGGSWCDS
Sbjct: 361 EVDLAHTTLAYGLNQEEFTDGEEEEEEEDTAAGEPSRDTRGAAGPLDKGGSWCDS 415
>gi|7110697 protein interacting with C kinase 1 [Homo sapiens]
Length = 415
Score = 827 bits (2137), Expect = 0.0
Identities = 415/415 (100%), Positives = 415/415 (100%)
Query: 1 MFADLDYDIEEDKLGIPTVPGKVTLQKDAQNLIGISIGGGAQYCPCLYIVQVFDNTPAAL 60
MFADLDYDIEEDKLGIPTVPGKVTLQKDAQNLIGISIGGGAQYCPCLYIVQVFDNTPAAL
Sbjct: 1 MFADLDYDIEEDKLGIPTVPGKVTLQKDAQNLIGISIGGGAQYCPCLYIVQVFDNTPAAL 60
Query: 61 DGTVAAGDEITGVNGRSIKGKTKVEVAKMIQEVKGEVTIHYNKLQADPKQGMSLDIVLKK 120
DGTVAAGDEITGVNGRSIKGKTKVEVAKMIQEVKGEVTIHYNKLQADPKQGMSLDIVLKK
Sbjct: 61 DGTVAAGDEITGVNGRSIKGKTKVEVAKMIQEVKGEVTIHYNKLQADPKQGMSLDIVLKK 120
Query: 121 VKHRLVENMSSGTADALGLSRAILCNDGLVKRLEELERTAELYKGMTEHTKNLLRAFYEL 180
VKHRLVENMSSGTADALGLSRAILCNDGLVKRLEELERTAELYKGMTEHTKNLLRAFYEL
Sbjct: 121 VKHRLVENMSSGTADALGLSRAILCNDGLVKRLEELERTAELYKGMTEHTKNLLRAFYEL 180
Query: 181 SQTHRAFGDVFSVIGVREPQPAASEAFVKFADAHRSIEKFGIRLLKTIKPMLTDLNTYLN 240
SQTHRAFGDVFSVIGVREPQPAASEAFVKFADAHRSIEKFGIRLLKTIKPMLTDLNTYLN
Sbjct: 181 SQTHRAFGDVFSVIGVREPQPAASEAFVKFADAHRSIEKFGIRLLKTIKPMLTDLNTYLN 240
Query: 241 KAIPDTRLTIKKYLDVKFEYLSYCLKVKEMDDEEYSCIALGEPLYRVSTGNYEYRLILRC 300
KAIPDTRLTIKKYLDVKFEYLSYCLKVKEMDDEEYSCIALGEPLYRVSTGNYEYRLILRC
Sbjct: 241 KAIPDTRLTIKKYLDVKFEYLSYCLKVKEMDDEEYSCIALGEPLYRVSTGNYEYRLILRC 300
Query: 301 RQEARARFSQMRKDVLEKMELLDQKHVQDIVFQLQRLVSTMSKYYNDCYAVLRDADVFPI 360
RQEARARFSQMRKDVLEKMELLDQKHVQDIVFQLQRLVSTMSKYYNDCYAVLRDADVFPI
Sbjct: 301 RQEARARFSQMRKDVLEKMELLDQKHVQDIVFQLQRLVSTMSKYYNDCYAVLRDADVFPI 360
Query: 361 EVDLAHTTLAYGLNQEEFTDGEEEEEEEDTAAGEPSRDTRGAAGPLDKGGSWCDS 415
EVDLAHTTLAYGLNQEEFTDGEEEEEEEDTAAGEPSRDTRGAAGPLDKGGSWCDS
Sbjct: 361 EVDLAHTTLAYGLNQEEFTDGEEEEEEEDTAAGEPSRDTRGAAGPLDKGGSWCDS 415
>gi|6912602 ADP-ribosylation factor interacting protein 2 [Homo
sapiens]
Length = 341
Score = 62.8 bits (151), Expect = 6e-10
Identities = 49/194 (25%), Positives = 92/194 (47%), Gaps = 13/194 (6%)
Query: 152 RLEELERTAELYKGMTEHTKNLLRAFYELSQTHRAFGDVFSVIGVREPQPAASEAFVKFA 211
++E L T Y+ + + + L Y L QT A GD F+ + + P+ E F A
Sbjct: 129 QIELLRETKRKYESVLQLGRALTAHLYSLLQTQHALGDAFADLSQKSPE--LQEEFGYNA 186
Query: 212 DAHRSIEKFGIRLLKTIKPMLTDLNTYLNKAIPDTRLTIKKYLDVKFEYLSYCLKVKEMD 271
+ + + K G LL + ++ +NT + K + DT +T+K+Y + EY +Y ++E
Sbjct: 187 ETQKLLCKNGETLLGAVNFFVSSINTLVTKTMEDTLMTVKQYEAARLEYDAYRTDLEE-- 244
Query: 272 DEEYSCIALGEPLYRVSTGNYEYRLILRCRQEARARFSQMRKDVLEKMELLDQKHVQDIV 331
++LG P + G E Q R ++ ++R DV K++ L++ ++ +
Sbjct: 245 ------LSLG-PRDAGTRGRLE--SAQATFQAHRDKYEKLRGDVAIKLKFLEENKIKVMH 295
Query: 332 FQLQRLVSTMSKYY 345
QL + +S Y+
Sbjct: 296 KQLLLFHNAVSAYF 309
>gi|71040094 ADP-ribosylation factor interacting protein 1 isoform 1
[Homo sapiens]
Length = 373
Score = 61.6 bits (148), Expect = 1e-09
Identities = 44/197 (22%), Positives = 92/197 (46%), Gaps = 13/197 (6%)
Query: 149 LVKRLEELERTAELYKGMTEHTKNLLRAFYELSQTHRAFGDVFSVIGVREPQPAASEAFV 208
L +++ L + Y+ + + + L +++ T R GD F+ + ++ + E F
Sbjct: 158 LEAQIDILRDNKKKYENILKLAQTLSTQLFQMVHTQRQLGDAFADLSLKSLE--LHEEFG 215
Query: 209 KFADAHRSIEKFGIRLLKTIKPMLTDLNTYLNKAIPDTRLTIKKYLDVKFEYLSYCLKVK 268
AD + + K G LL I + +NT +NK I DT +T+K+Y + EY +Y ++
Sbjct: 216 YNADTQKLLAKNGETLLGAINFFIASVNTLVNKTIEDTLMTVKQYESARIEYDAYRTDLE 275
Query: 269 EMDDEEYSCIALGEPLYRVSTGNYEYRLILRCRQEARARFSQMRKDVLEKMELLDQKHVQ 328
E++ L ++ + + Q + ++ +MR DV K++ L++ V+
Sbjct: 276 ELNLGPRD----ANTLPKIEQSQHLF-------QAHKEKYDKMRNDVSVKLKFLEENKVK 324
Query: 329 DIVFQLQRLVSTMSKYY 345
+ QL + ++ Y+
Sbjct: 325 VLHNQLVLFHNAIAAYF 341
>gi|71040092 ADP-ribosylation factor interacting protein 1 isoform 2
[Homo sapiens]
Length = 341
Score = 61.6 bits (148), Expect = 1e-09
Identities = 44/197 (22%), Positives = 92/197 (46%), Gaps = 13/197 (6%)
Query: 149 LVKRLEELERTAELYKGMTEHTKNLLRAFYELSQTHRAFGDVFSVIGVREPQPAASEAFV 208
L +++ L + Y+ + + + L +++ T R GD F+ + ++ + E F
Sbjct: 126 LEAQIDILRDNKKKYENILKLAQTLSTQLFQMVHTQRQLGDAFADLSLKSLE--LHEEFG 183
Query: 209 KFADAHRSIEKFGIRLLKTIKPMLTDLNTYLNKAIPDTRLTIKKYLDVKFEYLSYCLKVK 268
AD + + K G LL I + +NT +NK I DT +T+K+Y + EY +Y ++
Sbjct: 184 YNADTQKLLAKNGETLLGAINFFIASVNTLVNKTIEDTLMTVKQYESARIEYDAYRTDLE 243
Query: 269 EMDDEEYSCIALGEPLYRVSTGNYEYRLILRCRQEARARFSQMRKDVLEKMELLDQKHVQ 328
E++ L ++ + + Q + ++ +MR DV K++ L++ V+
Sbjct: 244 ELNLGPRD----ANTLPKIEQSQHLF-------QAHKEKYDKMRNDVSVKLKFLEENKVK 292
Query: 329 DIVFQLQRLVSTMSKYY 345
+ QL + ++ Y+
Sbjct: 293 VLHNQLVLFHNAIAAYF 309
>gi|7657210 ADP-ribosylation factor interacting protein 1 isoform 2
[Homo sapiens]
Length = 341
Score = 61.6 bits (148), Expect = 1e-09
Identities = 44/197 (22%), Positives = 92/197 (46%), Gaps = 13/197 (6%)
Query: 149 LVKRLEELERTAELYKGMTEHTKNLLRAFYELSQTHRAFGDVFSVIGVREPQPAASEAFV 208
L +++ L + Y+ + + + L +++ T R GD F+ + ++ + E F
Sbjct: 126 LEAQIDILRDNKKKYENILKLAQTLSTQLFQMVHTQRQLGDAFADLSLKSLE--LHEEFG 183
Query: 209 KFADAHRSIEKFGIRLLKTIKPMLTDLNTYLNKAIPDTRLTIKKYLDVKFEYLSYCLKVK 268
AD + + K G LL I + +NT +NK I DT +T+K+Y + EY +Y ++
Sbjct: 184 YNADTQKLLAKNGETLLGAINFFIASVNTLVNKTIEDTLMTVKQYESARIEYDAYRTDLE 243
Query: 269 EMDDEEYSCIALGEPLYRVSTGNYEYRLILRCRQEARARFSQMRKDVLEKMELLDQKHVQ 328
E++ L ++ + + Q + ++ +MR DV K++ L++ V+
Sbjct: 244 ELNLGPRD----ANTLPKIEQSQHLF-------QAHKEKYDKMRNDVSVKLKFLEENKVK 292
Query: 329 DIVFQLQRLVSTMSKYY 345
+ QL + ++ Y+
Sbjct: 293 VLHNQLVLFHNAIAAYF 309
>gi|148746189 multiple PDZ domain protein [Homo sapiens]
Length = 2041
Score = 47.4 bits (111), Expect = 2e-05
Identities = 34/95 (35%), Positives = 50/95 (52%), Gaps = 7/95 (7%)
Query: 9 IEEDKLGIPTVPGKVTLQKDAQNLIGISIGGGAQY----CPCLYIVQVFDNTPAALDGTV 64
I +D LG P +TL++ L G SI GG P +Y+ VF A+ DG +
Sbjct: 1946 IFQDDLGPPQCKS-ITLERGPDGL-GFSIVGGYGSPHGDLP-IYVKTVFAKGAASEDGRL 2002
Query: 65 AAGDEITGVNGRSIKGKTKVEVAKMIQEVKGEVTI 99
GD+I VNG+S++G T E +++ KG VT+
Sbjct: 2003 KRGDQIIAVNGQSLEGVTHEEAVAILKRTKGTVTL 2037
Score = 39.3 bits (90), Expect = 0.007
Identities = 32/129 (24%), Positives = 57/129 (44%), Gaps = 20/129 (15%)
Query: 12 DKLGIPTVPGKVTLQKDAQNLIGIS---IGGGAQYCPCLYIVQVFDNTPAALDGTVAAGD 68
D P +PG T + ++ G+ +GG + I +V++ A DG + AGD
Sbjct: 1616 DPATCPIIPGCETTIEISKGRTGLGLSIVGGSDTLLGAIIIHEVYEEGAACKDGRLWAGD 1675
Query: 69 EITGVNGRSIKGKTKVEVAKMIQEVKGEV--TIHYN---------------KLQADPKQG 111
+I VNG ++ T E ++++ V T++ + +LQ P +G
Sbjct: 1676 QILEVNGIDLRKATHDEAINVLRQTPQRVRLTLYRDEAPYKEEEVCDTLTIELQKKPGKG 1735
Query: 112 MSLDIVLKK 120
+ L IV K+
Sbjct: 1736 LGLSIVGKR 1744
Score = 38.1 bits (87), Expect = 0.015
Identities = 23/100 (23%), Positives = 46/100 (46%), Gaps = 9/100 (9%)
Query: 20 PGKVTLQKDAQNLIGISIGGG---------AQYCPCLYIVQVFDNTPAALDGTVAAGDEI 70
P +V L ++ +GISI GG + ++I V +++PA +GT+ GD I
Sbjct: 1149 PRRVELWREPSKSLGISIVGGRGMGSRLSNGEVMRGIFIKHVLEDSPAGKNGTLKPGDRI 1208
Query: 71 TGVNGRSIKGKTKVEVAKMIQEVKGEVTIHYNKLQADPKQ 110
V+G ++ + + + I++ V + P++
Sbjct: 1209 VEVDGMDLRDASHEQAVEAIRKAGNPVVFMVQSIINRPRK 1248
Score = 37.0 bits (84), Expect = 0.033
Identities = 36/164 (21%), Positives = 67/164 (40%), Gaps = 14/164 (8%)
Query: 48 YIVQVFDNTPAALDGTVAAGDEITGVNGRSIKGKTKVEVAKMIQEVKGEVTIHYNKLQAD 107
+I V P G + +GDE+ VNG ++ G+ +V +++E+ EVT+ +
Sbjct: 577 FIRSVLPEGPVGHSGKLFSGDELLEVNGITLLGENHQDVVNILKELPIEVTMVCCRRTVP 636
Query: 108 PKQGMSLDIVLKKVKHRLVENMSSGTADALGLSRA---ILCNDGLVKRLEELERTAELYK 164
P LD L L E + +G S +L + EE++ +++
Sbjct: 637 PTTQSELD-SLDLCDIELTEKPHVDLGEFIGSSETEDPVLAMTDAGQSTEEVQAPLAMWE 695
Query: 165 GMTEHTKNLLRAFYELSQTHRAFGDVFSVIGVREPQPAASEAFV 208
+H EL + + G FS++ ++P AS +
Sbjct: 696 AGIQH--------IELEKGSKGLG--FSILDYQDPIDPASTVII 729
Score = 35.8 bits (81), Expect = 0.073
Identities = 27/125 (21%), Positives = 55/125 (44%), Gaps = 6/125 (4%)
Query: 23 VTLQKDAQNLIGISIGGGAQYCPCLYIVQVFDNTPAALDGTVAAGDEITGVNGRSIKGKT 82
+ LQK +G+SI G +++ + A DG + GD+I VNG ++ T
Sbjct: 1726 IELQKKPGKGLGLSIVGKRNDTG-VFVSDIVKGGIADADGRLMQGDQILMVNGEDVRNAT 1784
Query: 83 KVEVAKMIQEVKGEVT-----IHYNKLQADPKQGMSLDIVLKKVKHRLVENMSSGTADAL 137
+ VA +++ +G ++ + + + + + +++ M G D+L
Sbjct: 1785 QEAVAALLKVSEGSLSSFTFPLSGSSTSESLESSSKKNALASEIQGLRTVEMKKGPTDSL 1844
Query: 138 GLSRA 142
G+S A
Sbjct: 1845 GISIA 1849
Score = 30.4 bits (67), Expect = 3.1
Identities = 17/68 (25%), Positives = 34/68 (50%), Gaps = 1/68 (1%)
Query: 33 IGISIGGGAQYCPC-LYIVQVFDNTPAALDGTVAAGDEITGVNGRSIKGKTKVEVAKMIQ 91
+G+S+ G ++IV + N A DG + DE+ +NG+ + G++ + +I+
Sbjct: 1360 LGLSLAGNKDRSRMSVFIVGIDPNGAAGKDGRLQIADELLEINGQILYGRSHQNASSIIK 1419
Query: 92 EVKGEVTI 99
+V I
Sbjct: 1420 CAPSKVKI 1427
Score = 28.9 bits (63), Expect = 9.0
Identities = 19/73 (26%), Positives = 39/73 (53%), Gaps = 5/73 (6%)
Query: 23 VTLQKDAQNLIGISIGG---GAQYCPC-LYIVQVFDNTPAALDGTVAAGDEITGVNGRSI 78
V L K+ Q L GI+I G + P +++ + ++ DG + GD+I V+G ++
Sbjct: 378 VELTKNVQGL-GITIAGYIGDKKLEPSGIFVKSITKSSAVEHDGRIQIGDQIIAVDGTNL 436
Query: 79 KGKTKVEVAKMIQ 91
+G T + ++++
Sbjct: 437 QGFTNQQAVEVLR 449
>gi|187607085 ligand of numb-protein X 1 isoform a [Homo sapiens]
Length = 728
Score = 47.4 bits (111), Expect = 2e-05
Identities = 24/80 (30%), Positives = 43/80 (53%), Gaps = 3/80 (3%)
Query: 23 VTLQKDAQNLIGISIGGGAQYC---PCLYIVQVFDNTPAALDGTVAAGDEITGVNGRSIK 79
+ L+++ +G I GG + +I + + TPA DG + GD + VNGRS
Sbjct: 639 IVLRRNTAGSLGFCIVGGYEEYNGNKPFFIKSIVEGTPAYNDGRIRCGDILLAVNGRSTS 698
Query: 80 GKTKVEVAKMIQEVKGEVTI 99
G +A++++E+KG +T+
Sbjct: 699 GMIHACLARLLKELKGRITL 718
Score = 35.4 bits (80), Expect = 0.096
Identities = 17/80 (21%), Positives = 38/80 (47%), Gaps = 3/80 (3%)
Query: 23 VTLQKDAQNLIGISIGGGAQYCPC---LYIVQVFDNTPAALDGTVAAGDEITGVNGRSIK 79
V +QKD +G+++ GGA + +Y++ V + DG + GD + V+G +
Sbjct: 508 VNIQKDPGESLGMTVAGGASHREWDLPIYVISVEPGGVISRDGRIKTGDILLNVDGVELT 567
Query: 80 GKTKVEVAKMIQEVKGEVTI 99
++ E +++ + +
Sbjct: 568 EVSRSEAVALLKRTSSSIVL 587
>gi|187607071 ligand of numb-protein X 1 isoform b [Homo sapiens]
Length = 632
Score = 47.4 bits (111), Expect = 2e-05
Identities = 24/80 (30%), Positives = 43/80 (53%), Gaps = 3/80 (3%)
Query: 23 VTLQKDAQNLIGISIGGGAQYC---PCLYIVQVFDNTPAALDGTVAAGDEITGVNGRSIK 79
+ L+++ +G I GG + +I + + TPA DG + GD + VNGRS
Sbjct: 543 IVLRRNTAGSLGFCIVGGYEEYNGNKPFFIKSIVEGTPAYNDGRIRCGDILLAVNGRSTS 602
Query: 80 GKTKVEVAKMIQEVKGEVTI 99
G +A++++E+KG +T+
Sbjct: 603 GMIHACLARLLKELKGRITL 622
Score = 35.4 bits (80), Expect = 0.096
Identities = 17/80 (21%), Positives = 38/80 (47%), Gaps = 3/80 (3%)
Query: 23 VTLQKDAQNLIGISIGGGAQYCPC---LYIVQVFDNTPAALDGTVAAGDEITGVNGRSIK 79
V +QKD +G+++ GGA + +Y++ V + DG + GD + V+G +
Sbjct: 412 VNIQKDPGESLGMTVAGGASHREWDLPIYVISVEPGGVISRDGRIKTGDILLNVDGVELT 471
Query: 80 GKTKVEVAKMIQEVKGEVTI 99
++ E +++ + +
Sbjct: 472 EVSRSEAVALLKRTSSSIVL 491
>gi|9507165 syntrophin, gamma 2 [Homo sapiens]
Length = 539
Score = 47.0 bits (110), Expect = 3e-05
Identities = 26/86 (30%), Positives = 46/86 (53%)
Query: 23 VTLQKDAQNLIGISIGGGAQYCPCLYIVQVFDNTPAALDGTVAAGDEITGVNGRSIKGKT 82
VTL++ +G+SI GG+++ + I ++F++ A G + GD + VNG ++ T
Sbjct: 74 VTLRRQPVGGLGLSIKGGSEHNVPVVISKIFEDQAADQTGMLFVGDAVLQVNGIHVENAT 133
Query: 83 KVEVAKMIQEVKGEVTIHYNKLQADP 108
EV +++ EVTI L+ P
Sbjct: 134 HEEVVHLLRNAGDEVTITVEYLREAP 159
>gi|148833504 interleukin 16 isoform 2 [Homo sapiens]
Length = 1332
Score = 46.6 bits (109), Expect = 4e-05
Identities = 31/119 (26%), Positives = 60/119 (50%), Gaps = 16/119 (13%)
Query: 25 LQKDAQNLIGISIGGGAQY-CPCLYIVQVFDNTPAALDGTVAAGDEITGVNGRSIKGKTK 83
L K+ +G S+ GGA + + +VF N A+ +GT+ G+E+ +NG+S+KG T
Sbjct: 1116 LHKEEGAGLGFSLAGGADLENKVITVHRVFPNGLASQEGTIQKGNEVLSINGKSLKGTTH 1175
Query: 84 VEVAKMIQEVKGEVTIHYNKLQADPKQGMSLDIVLKKVKHRLVENMSSGTADALGLSRA 142
+ ++++ + +P+Q + IV +K+ + +++S T A S A
Sbjct: 1176 HDALAILRQAR------------EPRQAV---IVTRKLTPEAMPDLNSSTDSAASASAA 1219
Score = 42.0 bits (97), Expect = 0.001
Identities = 30/86 (34%), Positives = 43/86 (50%), Gaps = 4/86 (4%)
Query: 18 TVPGKVTLQKDAQNLIGISIGGGAQ--YCPC-LYIVQVFDNTPAALDGTVAAGDEITGVN 74
+V + L K +G SI GG Y P +Y+ +F AA DG + GDEI +N
Sbjct: 212 SVISNIVLMKGQAKGLGFSIVGGKDSIYGPIGIYVKTIFAGGAAAADGRLQEGDEILELN 271
Query: 75 GRSIKGKTKVE-VAKMIQEVKGEVTI 99
G S+ G T + + K Q KG +T+
Sbjct: 272 GESMAGLTHQDALQKFKQAKKGLLTL 297
Score = 29.3 bits (64), Expect = 6.9
Identities = 34/116 (29%), Positives = 54/116 (46%), Gaps = 11/116 (9%)
Query: 22 KVTLQKDAQNLIGISIG-GGAQYCPCLYIVQVFDNTP---AALDGTVAAGDEITGVNGRS 77
+V+LQK+A +G+ IG Y C+ + V +P A LDG + GDEI ++
Sbjct: 355 EVSLQKEAG--VGLGIGLCSVPYFQCISGIFVHTLSPGSVAHLDGRLRCGDEIVEISDSP 412
Query: 78 IKGKTKVEVAKMIQEV-KGEVTIHYNKLQADPKQGMSLDIVLKKVKHRLVENMSSG 132
+ T EV ++ G V I ++ DP+ + LK+ + VEN G
Sbjct: 413 VHCLTLNEVYTILSHCDPGPVPIIVSR-HPDPQVS---EQQLKEAVAQAVENTKFG 464
>gi|27262655 interleukin 16 isoform 1 precursor [Homo sapiens]
Length = 631
Score = 46.6 bits (109), Expect = 4e-05
Identities = 31/119 (26%), Positives = 60/119 (50%), Gaps = 16/119 (13%)
Query: 25 LQKDAQNLIGISIGGGAQY-CPCLYIVQVFDNTPAALDGTVAAGDEITGVNGRSIKGKTK 83
L K+ +G S+ GGA + + +VF N A+ +GT+ G+E+ +NG+S+KG T
Sbjct: 415 LHKEEGAGLGFSLAGGADLENKVITVHRVFPNGLASQEGTIQKGNEVLSINGKSLKGTTH 474
Query: 84 VEVAKMIQEVKGEVTIHYNKLQADPKQGMSLDIVLKKVKHRLVENMSSGTADALGLSRA 142
+ ++++ + +P+Q + IV +K+ + +++S T A S A
Sbjct: 475 HDALAILRQAR------------EPRQAV---IVTRKLTPEAMPDLNSSTDSAASASAA 518
>gi|218505835 membrane-associated guanylate kinase-related 3 isoform
1 [Homo sapiens]
Length = 1481
Score = 44.3 bits (103), Expect = 2e-04
Identities = 20/58 (34%), Positives = 34/58 (58%)
Query: 34 GISIGGGAQYCPCLYIVQVFDNTPAALDGTVAAGDEITGVNGRSIKGKTKVEVAKMIQ 91
G S+ GG +Y L+I+++ ++ PA DG + GD+I +NG +G T ++IQ
Sbjct: 1032 GFSLRGGKEYNMGLFILRLAEDGPAIKDGRIHVGDQIVEINGEPTQGITHTRAIELIQ 1089
Score = 43.9 bits (102), Expect = 3e-04
Identities = 34/112 (30%), Positives = 50/112 (44%), Gaps = 1/112 (0%)
Query: 22 KVTLQKDAQNLIGISIGGGAQYCPCLYIVQVFDNTPAALDGTVAAGDEITGVNGRSIKGK 81
+ +L+K G +I GG + L + V + PAA DG +A GD I +NG + G
Sbjct: 410 RASLKKSTMGF-GFTIIGGDRPDEFLQVKNVLKDGPAAQDGKIAPGDVIVDINGNCVLGH 468
Query: 82 TKVEVAKMIQEVKGEVTIHYNKLQADPKQGMSLDIVLKKVKHRLVENMSSGT 133
T +V +M Q V ++ + P S D V+ V V N S T
Sbjct: 469 THADVVQMFQLVPVNQYVNLTLCRGYPLPDDSEDPVVDIVAATPVINGQSLT 520
Score = 31.2 bits (69), Expect = 1.8
Identities = 16/51 (31%), Positives = 29/51 (56%)
Query: 49 IVQVFDNTPAALDGTVAAGDEITGVNGRSIKGKTKVEVAKMIQEVKGEVTI 99
I +V + +PA G + GD I+ VNG+SI + + ++I++ VT+
Sbjct: 882 IGRVIEGSPADRCGKLKVGDHISAVNGQSIVELSHDNIVQLIKDAGVTVTL 932
Score = 29.3 bits (64), Expect = 6.9
Identities = 16/57 (28%), Positives = 28/57 (49%)
Query: 34 GISIGGGAQYCPCLYIVQVFDNTPAALDGTVAAGDEITGVNGRSIKGKTKVEVAKMI 90
G + GG +YI + A DG + A DE+ ++G +KGK+ +V ++
Sbjct: 737 GFRVLGGDGPDQSIYIGAIIPLGAAEKDGRLRAADELMCIDGIPVKGKSHKQVLDLM 793
>gi|155969695 membrane-associated guanylate kinase-related 3 isoform
2 [Homo sapiens]
Length = 1125
Score = 44.3 bits (103), Expect = 2e-04
Identities = 20/58 (34%), Positives = 34/58 (58%)
Query: 34 GISIGGGAQYCPCLYIVQVFDNTPAALDGTVAAGDEITGVNGRSIKGKTKVEVAKMIQ 91
G S+ GG +Y L+I+++ ++ PA DG + GD+I +NG +G T ++IQ
Sbjct: 1032 GFSLRGGKEYNMGLFILRLAEDGPAIKDGRIHVGDQIVEINGEPTQGITHTRAIELIQ 1089
Score = 43.9 bits (102), Expect = 3e-04
Identities = 34/112 (30%), Positives = 50/112 (44%), Gaps = 1/112 (0%)
Query: 22 KVTLQKDAQNLIGISIGGGAQYCPCLYIVQVFDNTPAALDGTVAAGDEITGVNGRSIKGK 81
+ +L+K G +I GG + L + V + PAA DG +A GD I +NG + G
Sbjct: 410 RASLKKSTMGF-GFTIIGGDRPDEFLQVKNVLKDGPAAQDGKIAPGDVIVDINGNCVLGH 468
Query: 82 TKVEVAKMIQEVKGEVTIHYNKLQADPKQGMSLDIVLKKVKHRLVENMSSGT 133
T +V +M Q V ++ + P S D V+ V V N S T
Sbjct: 469 THADVVQMFQLVPVNQYVNLTLCRGYPLPDDSEDPVVDIVAATPVINGQSLT 520
Score = 31.2 bits (69), Expect = 1.8
Identities = 16/51 (31%), Positives = 29/51 (56%)
Query: 49 IVQVFDNTPAALDGTVAAGDEITGVNGRSIKGKTKVEVAKMIQEVKGEVTI 99
I +V + +PA G + GD I+ VNG+SI + + ++I++ VT+
Sbjct: 882 IGRVIEGSPADRCGKLKVGDHISAVNGQSIVELSHDNIVQLIKDAGVTVTL 932
Score = 29.3 bits (64), Expect = 6.9
Identities = 16/57 (28%), Positives = 28/57 (49%)
Query: 34 GISIGGGAQYCPCLYIVQVFDNTPAALDGTVAAGDEITGVNGRSIKGKTKVEVAKMI 90
G + GG +YI + A DG + A DE+ ++G +KGK+ +V ++
Sbjct: 737 GFRVLGGDGPDQSIYIGAIIPLGAAEKDGRLRAADELMCIDGIPVKGKSHKQVLDLM 793
>gi|90819237 myeloid/lymphoid or mixed-lineage leukemia (trithorax
homolog, Drosophila); translocated to, 4 isoform 1 [Homo
sapiens]
Length = 1834
Score = 43.9 bits (102), Expect = 3e-04
Identities = 29/84 (34%), Positives = 46/84 (54%), Gaps = 5/84 (5%)
Query: 23 VTLQKDAQNLIGISI---GGGAQYCPCLYIVQVFDNTPAALDGTVAAGDEITGVNGRSIK 79
VTL+K QN +G+SI G Q +Y+ V A +DG +AAGD++ V+GRS+
Sbjct: 1009 VTLKK--QNGMGLSIVAAKGAGQDKLGIYVKSVVKGGAADVDGRLAAGDQLLSVDGRSLV 1066
Query: 80 GKTKVEVAKMIQEVKGEVTIHYNK 103
G ++ A+++ VT+ K
Sbjct: 1067 GLSQERAAELMTRTSSVVTLEVAK 1090
>gi|90819233 myeloid/lymphoid or mixed-lineage leukemia (trithorax
homolog, Drosophila); translocated to, 4 isoform 2 [Homo
sapiens]
Length = 1651
Score = 43.9 bits (102), Expect = 3e-04
Identities = 29/84 (34%), Positives = 46/84 (54%), Gaps = 5/84 (5%)
Query: 23 VTLQKDAQNLIGISI---GGGAQYCPCLYIVQVFDNTPAALDGTVAAGDEITGVNGRSIK 79
VTL+K QN +G+SI G Q +Y+ V A +DG +AAGD++ V+GRS+
Sbjct: 1010 VTLKK--QNGMGLSIVAAKGAGQDKLGIYVKSVVKGGAADVDGRLAAGDQLLSVDGRSLV 1067
Query: 80 GKTKVEVAKMIQEVKGEVTIHYNK 103
G ++ A+++ VT+ K
Sbjct: 1068 GLSQERAAELMTRTSSVVTLEVAK 1091
>gi|90819231 myeloid/lymphoid or mixed-lineage leukemia (trithorax
homolog, Drosophila); translocated to, 4 isoform 3 [Homo
sapiens]
Length = 1612
Score = 43.9 bits (102), Expect = 3e-04
Identities = 29/84 (34%), Positives = 46/84 (54%), Gaps = 5/84 (5%)
Query: 23 VTLQKDAQNLIGISI---GGGAQYCPCLYIVQVFDNTPAALDGTVAAGDEITGVNGRSIK 79
VTL+K QN +G+SI G Q +Y+ V A +DG +AAGD++ V+GRS+
Sbjct: 994 VTLKK--QNGMGLSIVAAKGAGQDKLGIYVKSVVKGGAADVDGRLAAGDQLLSVDGRSLV 1051
Query: 80 GKTKVEVAKMIQEVKGEVTIHYNK 103
G ++ A+++ VT+ K
Sbjct: 1052 GLSQERAAELMTRTSSVVTLEVAK 1075
>gi|27436957 membrane associated guanylate kinase, WW and PDZ domain
containing 2 [Homo sapiens]
Length = 1455
Score = 43.9 bits (102), Expect = 3e-04
Identities = 22/69 (31%), Positives = 40/69 (57%), Gaps = 1/69 (1%)
Query: 23 VTLQKDAQNLIGISIGGGAQYCPCLYIVQVFDNTPAALDGTVAAGDEITGVNGRSIKGKT 82
V ++K A+ G SI GG +Y LY++++ ++ PA +G + GD+I +NG S + T
Sbjct: 1148 VDMEKGAKGF-GFSIRGGREYKMDLYVLRLAEDGPAIRNGRMRVGDQIIEINGESTRDMT 1206
Query: 83 KVEVAKMIQ 91
++I+
Sbjct: 1207 HARAIELIK 1215
Score = 38.1 bits (87), Expect = 0.015
Identities = 24/70 (34%), Positives = 34/70 (48%), Gaps = 1/70 (1%)
Query: 24 TLQKDAQNLIGISIGGGAQYCPCLYIVQVFDNTPAALDGTVAAGDEITGVNGRSIKGKTK 83
TL+K G +I GG + L + V + PAA DG + GD I +N + G T
Sbjct: 428 TLKKSNMGF-GFTIIGGDEPDEFLQVKSVIPDGPAAQDGKMETGDVIVYINEVCVLGHTH 486
Query: 84 VEVAKMIQEV 93
+V K+ Q V
Sbjct: 487 ADVVKLFQSV 496
Score = 32.7 bits (73), Expect = 0.62
Identities = 16/51 (31%), Positives = 27/51 (52%)
Query: 49 IVQVFDNTPAALDGTVAAGDEITGVNGRSIKGKTKVEVAKMIQEVKGEVTI 99
I ++ D +PA + GD I VNG+SI ++ K+I++ VT+
Sbjct: 954 IGRIIDGSPADRCAKLKVGDRILAVNGQSIINMPHADIVKLIKDAGLSVTL 1004
>gi|21361831 partitioning-defective protein 3 homolog [Homo sapiens]
Length = 1356
Score = 43.1 bits (100), Expect = 5e-04
Identities = 26/87 (29%), Positives = 42/87 (48%), Gaps = 15/87 (17%)
Query: 35 ISIGGGAQYCPCLYIVQVFDNTPAALDGTVAAGDEITGVNGRSIKGKTKVEVAKMIQEVK 94
++IGG A +Y+ + A DG + AGD + VNG + GK++ EV +++ K
Sbjct: 480 VTIGGSAP----IYVKNILPRGAAIQDGRLKAGDRLIEVNGVDLVGKSQEEVVSLLRSTK 535
Query: 95 GEVTI-----------HYNKLQADPKQ 110
E T+ H +L A+P Q
Sbjct: 536 MEGTVSLLVFRQEDAFHPRELNAEPSQ 562
Score = 30.8 bits (68), Expect = 2.4
Identities = 11/45 (24%), Positives = 25/45 (55%)
Query: 47 LYIVQVFDNTPAALDGTVAAGDEITGVNGRSIKGKTKVEVAKMIQ 91
+++ + + A+ DG + D++ VNG S+ GKT + + ++
Sbjct: 619 IFVKSIINGGAASKDGRLRVNDQLIAVNGESLLGKTNQDAMETLR 663
>gi|87196343 PDZ domain containing 2 [Homo sapiens]
Length = 2839
Score = 43.1 bits (100), Expect = 5e-04
Identities = 27/81 (33%), Positives = 40/81 (49%), Gaps = 3/81 (3%)
Query: 17 PTVPGKVTLQKDAQNLIGISIGGGAQYCPC---LYIVQVFDNTPAALDGTVAAGDEITGV 73
P+V + L K+ +G SI GG +++ +F N AA DG + GDEI V
Sbjct: 581 PSVISIIGLYKEKGKGLGFSIAGGRDCIRGQMGIFVKTIFPNGSAAEDGRLKEGDEILDV 640
Query: 74 NGRSIKGKTKVEVAKMIQEVK 94
NG IKG T E ++++
Sbjct: 641 NGIPIKGLTFQEAIHTFKQIR 661
Score = 37.0 bits (84), Expect = 0.033
Identities = 20/73 (27%), Positives = 37/73 (50%), Gaps = 1/73 (1%)
Query: 23 VTLQKDAQNLIGISIGGGAQYCP-CLYIVQVFDNTPAALDGTVAAGDEITGVNGRSIKGK 81
+ L + + +G S+ GG P + + +VF A+ +GT+ GD + VNG S+ G
Sbjct: 2623 IVLNRKEGSGLGFSVAGGTDVEPKSITVHRVFSQGAASQEGTMNRGDFLLSVNGASLAGL 2682
Query: 82 TKVEVAKMIQEVK 94
V K++ + +
Sbjct: 2683 AHGNVLKVLHQAQ 2695
Score = 36.6 bits (83), Expect = 0.043
Identities = 23/80 (28%), Positives = 42/80 (52%), Gaps = 2/80 (2%)
Query: 22 KVTLQKDAQNL-IGISIGGGAQYCP-CLYIVQVFDNTPAALDGTVAAGDEITGVNGRSIK 79
K+ L K++ L I +S G G++ P + + QV + A DG ++ GDE+ +NG +
Sbjct: 334 KMELLKESDGLGIQVSGGRGSKRSPHAIVVTQVKEGGAAHRDGRLSLGDELLVINGHLLV 393
Query: 80 GKTKVEVAKMIQEVKGEVTI 99
G + E +++ G V +
Sbjct: 394 GLSHEEAVAILRSATGMVQL 413
Score = 30.4 bits (67), Expect = 3.1
Identities = 12/35 (34%), Positives = 21/35 (60%)
Query: 46 CLYIVQVFDNTPAALDGTVAAGDEITGVNGRSIKG 80
C+++ ++ N+PA G V DEI +NG+ + G
Sbjct: 118 CIWVTELRKNSPAGKSGKVRLRDEILSLNGQLMVG 152
Score = 30.4 bits (67), Expect = 3.1
Identities = 18/64 (28%), Positives = 31/64 (48%), Gaps = 3/64 (4%)
Query: 33 IGISIGGGAQYCPC---LYIVQVFDNTPAALDGTVAAGDEITGVNGRSIKGKTKVEVAKM 89
+G+S+ GG L I +V+ A G + AGDEI +NG+ + G + +
Sbjct: 2760 LGLSLDGGKSSVTGDGPLVIKRVYKGGAAEQAGIIEAGDEILAINGKPLVGLMHFDAWNI 2819
Query: 90 IQEV 93
++ V
Sbjct: 2820 MKSV 2823
>gi|9966877 golgi associated PDZ and coiled-coil motif containing
isoform a [Homo sapiens]
Length = 462
Score = 42.0 bits (97), Expect = 0.001
Identities = 23/76 (30%), Positives = 39/76 (51%)
Query: 22 KVTLQKDAQNLIGISIGGGAQYCPCLYIVQVFDNTPAALDGTVAAGDEITGVNGRSIKGK 81
KV L K+ +GISI GG ++ + I ++ PA G + GD I VNG +++
Sbjct: 288 KVLLLKEDHEGLGISITGGKEHGVPILISEIHPGQPADRCGGLHVGDAILAVNGVNLRDT 347
Query: 82 TKVEVAKMIQEVKGEV 97
E ++ + +GE+
Sbjct: 348 KHKEAVTILSQQRGEI 363
>gi|62868213 golgi associated PDZ and coiled-coil motif containing
isoform b [Homo sapiens]
Length = 454
Score = 42.0 bits (97), Expect = 0.001
Identities = 23/76 (30%), Positives = 39/76 (51%)
Query: 22 KVTLQKDAQNLIGISIGGGAQYCPCLYIVQVFDNTPAALDGTVAAGDEITGVNGRSIKGK 81
KV L K+ +GISI GG ++ + I ++ PA G + GD I VNG +++
Sbjct: 280 KVLLLKEDHEGLGISITGGKEHGVPILISEIHPGQPADRCGGLHVGDAILAVNGVNLRDT 339
Query: 82 TKVEVAKMIQEVKGEV 97
E ++ + +GE+
Sbjct: 340 KHKEAVTILSQQRGEI 355
>gi|18375648 protein tyrosine phosphatase, non-receptor type 13
isoform 3 [Homo sapiens]
Length = 2294
Score = 41.6 bits (96), Expect = 0.001
Identities = 32/115 (27%), Positives = 56/115 (48%), Gaps = 11/115 (9%)
Query: 6 DYDIEEDKLGIPTVPGK----VTLQKDAQNLIGISIGGGAQYCPC---LYIVQVFDNTPA 58
D D+ + I + P + V L+KDA+ +G I GG + ++I V PA
Sbjct: 882 DIDVLHKRWSIVSSPEREITLVNLKKDAKYGLGFQIIGGEKMGRLDLGIFISSVAPGGPA 941
Query: 59 ALDGTVAAGDEITGVNGRSIKGKTKVEVAKMIQEVKGEVTIHYNKLQADPKQGMS 113
LDG + GD + VN S++G + +++Q +VT+ + + PK+ +S
Sbjct: 942 DLDGCLKPGDRLISVNSVSLEGVSHHAAIEILQNAPEDVTL----VISQPKEKIS 992
Score = 36.6 bits (83), Expect = 0.043
Identities = 28/96 (29%), Positives = 44/96 (45%), Gaps = 7/96 (7%)
Query: 17 PTVPG---KVTLQKDAQNLIGISIGGGAQYCPC---LYIVQVFDNTPAALDGTVAAGDEI 70
P PG +V L K+ N +GIS+ GG +Y+ V A DG + GD +
Sbjct: 1169 PPKPGDIFEVELAKN-DNSLGISVTGGVNTSVRHGGIYVKAVIPQGAAESDGRIHKGDRV 1227
Query: 71 TGVNGRSIKGKTKVEVAKMIQEVKGEVTIHYNKLQA 106
VNG S++G T + + ++ V + K Q+
Sbjct: 1228 LAVNGVSLEGATHKQAVETLRNTGQVVHLLLEKGQS 1263
Score = 35.4 bits (80), Expect = 0.096
Identities = 18/49 (36%), Positives = 27/49 (55%)
Query: 49 IVQVFDNTPAALDGTVAAGDEITGVNGRSIKGKTKVEVAKMIQEVKGEV 97
+ ++F PAA G + GD I VNG S+KG ++ EV ++ EV
Sbjct: 1342 VKKLFPGQPAAESGKIDVGDVILKVNGASLKGLSQQEVISALRGTAPEV 1390
Score = 34.7 bits (78), Expect = 0.16
Identities = 24/106 (22%), Positives = 48/106 (45%), Gaps = 5/106 (4%)
Query: 4 DLDYDIEEDKLGIPTVPGKVTLQKDAQNLIGISIGGGAQYCPCLYIVQVFDNTPAALDGT 63
DL+ +E+ +L + + +TL K + +G ++ G Q C Y+ V + PA DG
Sbjct: 1582 DLENHLEDFELEVELL---ITLIKSEKGSLGFTVTKGNQRIGC-YVHDVIQD-PAKSDGR 1636
Query: 64 VAAGDEITGVNGRSIKGKTKVEVAKMIQEVKGEVTIHYNKLQADPK 109
+ GD + VN + T + +++ V + ++ P+
Sbjct: 1637 LKPGDRLIKVNDTDVTNMTHTDAVNLLRAASKTVRLVIGRVLELPR 1682
Score = 29.3 bits (64), Expect = 6.9
Identities = 21/75 (28%), Positives = 35/75 (46%)
Query: 16 IPTVPGKVTLQKDAQNLIGISIGGGAQYCPCLYIVQVFDNTPAALDGTVAAGDEITGVNG 75
+P + +TL + + L GG +YI + + AA++G + D I VNG
Sbjct: 1686 LPHLLPDITLTCNKEELGFSLCGGHDSLYQVVYISDINPRSVAAIEGNLQLLDVIHYVNG 1745
Query: 76 RSIKGKTKVEVAKMI 90
S +G T EV + +
Sbjct: 1746 VSTQGMTLEEVNRAL 1760
>gi|9507163 syntrophin, gamma 1 [Homo sapiens]
Length = 517
Score = 41.6 bits (96), Expect = 0.001
Identities = 31/127 (24%), Positives = 60/127 (47%), Gaps = 10/127 (7%)
Query: 23 VTLQKDAQNLIGISIGGGAQYCPCLYIVQVFDNTPAALDGTVAAGDEITGVNGRSIKGKT 82
VT+++ G+SI GGA++ + + ++ A L G + GD I +NG +++
Sbjct: 58 VTIRRQTVGGFGLSIKGGAEHNIPVVVSKISKEQRAELSGLLFIGDAILQINGINVRKCR 117
Query: 83 KVEVAKMIQEVKGEVTIHYNKLQADPKQGMSLDIVLKKVKHRLVENMSSGTADALGLSRA 142
EV ++++ EVT+ + L+ P +K L E+ + +D + +
Sbjct: 118 HEEVVQVLRNAGEEVTLTVSFLKRAP----------AFLKLPLNEDCACAPSDQSSGTSS 167
Query: 143 ILCNDGL 149
LC+ GL
Sbjct: 168 PLCDSGL 174
>gi|112382257 InaD-like [Homo sapiens]
Length = 1801
Score = 40.8 bits (94), Expect = 0.002
Identities = 26/84 (30%), Positives = 44/84 (52%), Gaps = 1/84 (1%)
Query: 23 VTLQKDAQNLIGISIGGGAQYCPCLYIVQVFDNTPAALDGTVAAGDEITGVNGRSIKGKT 82
V LQK A +G+SI G ++I + A LDG + GD+I VNG ++ +
Sbjct: 1534 VDLQKKAGRGLGLSIVGKRNGSG-VFISDIVKGGAADLDGRLIQGDQILSVNGEDMRNAS 1592
Query: 83 KVEVAKMIQEVKGEVTIHYNKLQA 106
+ VA +++ +G V + +L+A
Sbjct: 1593 QETVATILKCAQGLVQLEIGRLRA 1616
Score = 38.9 bits (89), Expect = 0.009
Identities = 30/109 (27%), Positives = 53/109 (48%), Gaps = 5/109 (4%)
Query: 12 DKLGIPTVPGK---VTLQKDAQNLIGISIGGGAQY-CPCLYIVQVFDNTPAALDGTVAAG 67
D P VPG+ + + K L G+SI GG + I +V++ AA DG + AG
Sbjct: 1424 DPATCPIVPGQEMIIEISKGRSGL-GLSIVGGKDTPLNAIVIHEVYEEGAAARDGRLWAG 1482
Query: 68 DEITGVNGRSIKGKTKVEVAKMIQEVKGEVTIHYNKLQADPKQGMSLDI 116
D+I VNG ++ + E +++ +V + + +A + +L+I
Sbjct: 1483 DQILEVNGVDLRNSSHEEAITALRQTPQKVRLVVYRDEAHYRDEENLEI 1531
Score = 37.4 bits (85), Expect = 0.025
Identities = 22/85 (25%), Positives = 46/85 (54%), Gaps = 5/85 (5%)
Query: 19 VPGK---VTLQKDAQNLIGISIGGGAQYCPC-LYIVQVFDNTPAALDGTVAAGDEITGVN 74
+PG+ + L+KD +N +G+S+ G +++V + PAA DG + GDE+ +N
Sbjct: 1233 LPGELHIIELEKD-KNGLGLSLAGNKDRSRMSIFVVGINPEGPAAADGRMRIGDELLEIN 1291
Query: 75 GRSIKGKTKVEVAKMIQEVKGEVTI 99
+ + G++ + +I+ +V +
Sbjct: 1292 NQILYGRSHQNASAIIKTAPSKVKL 1316
Score = 36.6 bits (83), Expect = 0.043
Identities = 22/96 (22%), Positives = 44/96 (45%), Gaps = 5/96 (5%)
Query: 8 DIEEDKLGIPTVPGKVTLQKDAQNLIGISIGGGAQYCPC----LYIVQVFDNTPAALDGT 63
D + G P V + ++ + +GISI GG + P ++I + + AA
Sbjct: 1662 DPSQKNSGTDMEPRTVEINRELSDALGISIAGG-RGSPLGDIPVFIAMIQASGVAARTQK 1720
Query: 64 VAAGDEITGVNGRSIKGKTKVEVAKMIQEVKGEVTI 99
+ GD I +NG+ + G + +V +++ G + +
Sbjct: 1721 LKVGDRIVSINGQPLDGLSHADVVNLLKNAYGRIIL 1756
Score = 33.9 bits (76), Expect = 0.28
Identities = 23/99 (23%), Positives = 43/99 (43%), Gaps = 9/99 (9%)
Query: 20 PGKVTLQKDAQNLIGISIGGG---------AQYCPCLYIVQVFDNTPAALDGTVAAGDEI 70
P V + ++ +GISI GG + ++I QV +++PA + GD+I
Sbjct: 1066 PRIVEIFREPNVSLGISIVGGQTVIKRLKNGEELKGIFIKQVLEDSPAGKTNALKTGDKI 1125
Query: 71 TGVNGRSIKGKTKVEVAKMIQEVKGEVTIHYNKLQADPK 109
V+G ++ + E + I+ V L + P+
Sbjct: 1126 LEVSGVDLQNASHSEAVEAIKNAGNPVVFIVQSLSSTPR 1164
Score = 30.0 bits (66), Expect = 4.0
Identities = 15/52 (28%), Positives = 24/52 (46%)
Query: 48 YIVQVFDNTPAALDGTVAAGDEITGVNGRSIKGKTKVEVAKMIQEVKGEVTI 99
YI + P G + DE+ VNG + GK++ E ++EV T+
Sbjct: 582 YISSIVSGGPVDTLGLLQPEDELLEVNGMQLYGKSRREAVSFLKEVPPPFTL 633
>gi|18375650 protein tyrosine phosphatase, non-receptor type 13
isoform 4 [Homo sapiens]
Length = 2490
Score = 40.4 bits (93), Expect = 0.003
Identities = 28/94 (29%), Positives = 48/94 (51%), Gaps = 7/94 (7%)
Query: 23 VTLQKDAQNLIGISIGGGAQYCPC---LYIVQVFDNTPAALDGTVAAGDEITGVNGRSIK 79
V L+KDA+ +G I GG + ++I V PA LDG + GD + VN S++
Sbjct: 1094 VNLKKDAKYGLGFQIIGGEKMGRLDLGIFISSVAPGGPADLDGCLKPGDRLISVNSVSLE 1153
Query: 80 GKTKVEVAKMIQEVKGEVTIHYNKLQADPKQGMS 113
G + +++Q +VT+ + + PK+ +S
Sbjct: 1154 GVSHHAAIEILQNAPEDVTL----VISQPKEKIS 1183
Score = 35.4 bits (80), Expect = 0.096
Identities = 18/49 (36%), Positives = 27/49 (55%)
Query: 49 IVQVFDNTPAALDGTVAAGDEITGVNGRSIKGKTKVEVAKMIQEVKGEV 97
+ ++F PAA G + GD I VNG S+KG ++ EV ++ EV
Sbjct: 1538 VKKLFPGQPAAESGKIDVGDVILKVNGASLKGLSQQEVISALRGTAPEV 1586
Score = 34.7 bits (78), Expect = 0.16
Identities = 24/106 (22%), Positives = 48/106 (45%), Gaps = 5/106 (4%)
Query: 4 DLDYDIEEDKLGIPTVPGKVTLQKDAQNLIGISIGGGAQYCPCLYIVQVFDNTPAALDGT 63
DL+ +E+ +L + + +TL K + +G ++ G Q C Y+ V + PA DG
Sbjct: 1778 DLENHLEDFELEVELL---ITLIKSEKGSLGFTVTKGNQRIGC-YVHDVIQD-PAKSDGR 1832
Query: 64 VAAGDEITGVNGRSIKGKTKVEVAKMIQEVKGEVTIHYNKLQADPK 109
+ GD + VN + T + +++ V + ++ P+
Sbjct: 1833 LKPGDRLIKVNDTDVTNMTHTDAVNLLRAASKTVRLVIGRVLELPR 1878
Score = 30.8 bits (68), Expect = 2.4
Identities = 16/60 (26%), Positives = 28/60 (46%)
Query: 47 LYIVQVFDNTPAALDGTVAAGDEITGVNGRSIKGKTKVEVAKMIQEVKGEVTIHYNKLQA 106
+Y+ V A DG + GD + VNG S++G T + + ++ V + K Q+
Sbjct: 1400 IYVKAVIPQGAAESDGRIHKGDRVLAVNGVSLEGATHKQAVETLRNTGQVVHLLLEKGQS 1459
Score = 29.3 bits (64), Expect = 6.9
Identities = 21/75 (28%), Positives = 35/75 (46%)
Query: 16 IPTVPGKVTLQKDAQNLIGISIGGGAQYCPCLYIVQVFDNTPAALDGTVAAGDEITGVNG 75
+P + +TL + + L GG +YI + + AA++G + D I VNG
Sbjct: 1882 LPHLLPDITLTCNKEELGFSLCGGHDSLYQVVYISDINPRSVAAIEGNLQLLDVIHYVNG 1941
Query: 76 RSIKGKTKVEVAKMI 90
S +G T EV + +
Sbjct: 1942 VSTQGMTLEEVNRAL 1956
>gi|18375646 protein tyrosine phosphatase, non-receptor type 13
isoform 1 [Homo sapiens]
Length = 2485
Score = 40.4 bits (93), Expect = 0.003
Identities = 28/94 (29%), Positives = 48/94 (51%), Gaps = 7/94 (7%)
Query: 23 VTLQKDAQNLIGISIGGGAQYCPC---LYIVQVFDNTPAALDGTVAAGDEITGVNGRSIK 79
V L+KDA+ +G I GG + ++I V PA LDG + GD + VN S++
Sbjct: 1094 VNLKKDAKYGLGFQIIGGEKMGRLDLGIFISSVAPGGPADLDGCLKPGDRLISVNSVSLE 1153
Query: 80 GKTKVEVAKMIQEVKGEVTIHYNKLQADPKQGMS 113
G + +++Q +VT+ + + PK+ +S
Sbjct: 1154 GVSHHAAIEILQNAPEDVTL----VISQPKEKIS 1183
Score = 36.6 bits (83), Expect = 0.043
Identities = 28/96 (29%), Positives = 44/96 (45%), Gaps = 7/96 (7%)
Query: 17 PTVPG---KVTLQKDAQNLIGISIGGGAQYCPC---LYIVQVFDNTPAALDGTVAAGDEI 70
P PG +V L K+ N +GIS+ GG +Y+ V A DG + GD +
Sbjct: 1360 PPKPGDIFEVELAKN-DNSLGISVTGGVNTSVRHGGIYVKAVIPQGAAESDGRIHKGDRV 1418
Query: 71 TGVNGRSIKGKTKVEVAKMIQEVKGEVTIHYNKLQA 106
VNG S++G T + + ++ V + K Q+
Sbjct: 1419 LAVNGVSLEGATHKQAVETLRNTGQVVHLLLEKGQS 1454
Score = 35.4 bits (80), Expect = 0.096
Identities = 18/49 (36%), Positives = 27/49 (55%)
Query: 49 IVQVFDNTPAALDGTVAAGDEITGVNGRSIKGKTKVEVAKMIQEVKGEV 97
+ ++F PAA G + GD I VNG S+KG ++ EV ++ EV
Sbjct: 1533 VKKLFPGQPAAESGKIDVGDVILKVNGASLKGLSQQEVISALRGTAPEV 1581
Score = 34.7 bits (78), Expect = 0.16
Identities = 24/106 (22%), Positives = 48/106 (45%), Gaps = 5/106 (4%)
Query: 4 DLDYDIEEDKLGIPTVPGKVTLQKDAQNLIGISIGGGAQYCPCLYIVQVFDNTPAALDGT 63
DL+ +E+ +L + + +TL K + +G ++ G Q C Y+ V + PA DG
Sbjct: 1773 DLENHLEDFELEVELL---ITLIKSEKGSLGFTVTKGNQRIGC-YVHDVIQD-PAKSDGR 1827
Query: 64 VAAGDEITGVNGRSIKGKTKVEVAKMIQEVKGEVTIHYNKLQADPK 109
+ GD + VN + T + +++ V + ++ P+
Sbjct: 1828 LKPGDRLIKVNDTDVTNMTHTDAVNLLRAASKTVRLVIGRVLELPR 1873
Score = 29.3 bits (64), Expect = 6.9
Identities = 21/75 (28%), Positives = 35/75 (46%)
Query: 16 IPTVPGKVTLQKDAQNLIGISIGGGAQYCPCLYIVQVFDNTPAALDGTVAAGDEITGVNG 75
+P + +TL + + L GG +YI + + AA++G + D I VNG
Sbjct: 1877 LPHLLPDITLTCNKEELGFSLCGGHDSLYQVVYISDINPRSVAAIEGNLQLLDVIHYVNG 1936
Query: 76 RSIKGKTKVEVAKMI 90
S +G T EV + +
Sbjct: 1937 VSTQGMTLEEVNRAL 1951
>gi|5453992 protein tyrosine phosphatase, non-receptor type 13 isoform
2 [Homo sapiens]
Length = 2466
Score = 40.4 bits (93), Expect = 0.003
Identities = 28/94 (29%), Positives = 48/94 (51%), Gaps = 7/94 (7%)
Query: 23 VTLQKDAQNLIGISIGGGAQYCPC---LYIVQVFDNTPAALDGTVAAGDEITGVNGRSIK 79
V L+KDA+ +G I GG + ++I V PA LDG + GD + VN S++
Sbjct: 1075 VNLKKDAKYGLGFQIIGGEKMGRLDLGIFISSVAPGGPADLDGCLKPGDRLISVNSVSLE 1134
Query: 80 GKTKVEVAKMIQEVKGEVTIHYNKLQADPKQGMS 113
G + +++Q +VT+ + + PK+ +S
Sbjct: 1135 GVSHHAAIEILQNAPEDVTL----VISQPKEKIS 1164
Score = 36.6 bits (83), Expect = 0.043
Identities = 28/96 (29%), Positives = 44/96 (45%), Gaps = 7/96 (7%)
Query: 17 PTVPG---KVTLQKDAQNLIGISIGGGAQYCPC---LYIVQVFDNTPAALDGTVAAGDEI 70
P PG +V L K+ N +GIS+ GG +Y+ V A DG + GD +
Sbjct: 1341 PPKPGDIFEVELAKN-DNSLGISVTGGVNTSVRHGGIYVKAVIPQGAAESDGRIHKGDRV 1399
Query: 71 TGVNGRSIKGKTKVEVAKMIQEVKGEVTIHYNKLQA 106
VNG S++G T + + ++ V + K Q+
Sbjct: 1400 LAVNGVSLEGATHKQAVETLRNTGQVVHLLLEKGQS 1435
Score = 35.4 bits (80), Expect = 0.096
Identities = 18/49 (36%), Positives = 27/49 (55%)
Query: 49 IVQVFDNTPAALDGTVAAGDEITGVNGRSIKGKTKVEVAKMIQEVKGEV 97
+ ++F PAA G + GD I VNG S+KG ++ EV ++ EV
Sbjct: 1514 VKKLFPGQPAAESGKIDVGDVILKVNGASLKGLSQQEVISALRGTAPEV 1562
Score = 34.7 bits (78), Expect = 0.16
Identities = 24/106 (22%), Positives = 48/106 (45%), Gaps = 5/106 (4%)
Query: 4 DLDYDIEEDKLGIPTVPGKVTLQKDAQNLIGISIGGGAQYCPCLYIVQVFDNTPAALDGT 63
DL+ +E+ +L + + +TL K + +G ++ G Q C Y+ V + PA DG
Sbjct: 1754 DLENHLEDFELEVELL---ITLIKSEKGSLGFTVTKGNQRIGC-YVHDVIQD-PAKSDGR 1808
Query: 64 VAAGDEITGVNGRSIKGKTKVEVAKMIQEVKGEVTIHYNKLQADPK 109
+ GD + VN + T + +++ V + ++ P+
Sbjct: 1809 LKPGDRLIKVNDTDVTNMTHTDAVNLLRAASKTVRLVIGRVLELPR 1854
Score = 29.3 bits (64), Expect = 6.9
Identities = 21/75 (28%), Positives = 35/75 (46%)
Query: 16 IPTVPGKVTLQKDAQNLIGISIGGGAQYCPCLYIVQVFDNTPAALDGTVAAGDEITGVNG 75
+P + +TL + + L GG +YI + + AA++G + D I VNG
Sbjct: 1858 LPHLLPDITLTCNKEELGFSLCGGHDSLYQVVYISDINPRSVAAIEGNLQLLDVIHYVNG 1917
Query: 76 RSIKGKTKVEVAKMI 90
S +G T EV + +
Sbjct: 1918 VSTQGMTLEEVNRAL 1932
>gi|110346445 FERM and PDZ domain containing 2 like 1 isoform 4
[Homo sapiens]
Length = 320
Score = 39.7 bits (91), Expect = 0.005
Identities = 21/51 (41%), Positives = 30/51 (58%)
Query: 49 IVQVFDNTPAALDGTVAAGDEITGVNGRSIKGKTKVEVAKMIQEVKGEVTI 99
I ++F PA +G +AAGD I VNGRS +G EV +++ EVT+
Sbjct: 122 IKRLFPGQPAEENGAIAAGDIILAVNGRSTEGLIFQEVLHLLRGAPQEVTL 172
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.317 0.136 0.387
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 15,033,988
Number of Sequences: 37866
Number of extensions: 650225
Number of successful extensions: 5527
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 118
Number of HSP's successfully gapped in prelim test: 68
Number of HSP's that attempted gapping in prelim test: 5127
Number of HSP's gapped (non-prelim): 425
length of query: 415
length of database: 18,247,518
effective HSP length: 105
effective length of query: 310
effective length of database: 14,271,588
effective search space: 4424192280
effective search space used: 4424192280
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.