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Search of human proteins with 87080813
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|87080813 LON peptidase N-terminal domain and ring finger 1
[Homo sapiens]
(773 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|87080813 LON peptidase N-terminal domain and ring finger 1 [H... 1578 0.0
gi|148528975 LON peptidase N-terminal domain and ring finger 2 [... 498 e-141
gi|73747840 LON peptidase N-terminal domain and ring finger 3 is... 496 e-140
gi|37622896 LON peptidase N-terminal domain and ring finger 3 is... 409 e-114
gi|224028289 tetratricopeptide repeat domain 28 [Homo sapiens] 56 1e-07
gi|31377566 ring finger protein 168 [Homo sapiens] 56 1e-07
gi|24025688 ligand of numb-protein X 2 [Homo sapiens] 54 6e-07
gi|237681119 breast cancer 1, early onset isoform 2 [Homo sapiens] 54 7e-07
gi|237681125 breast cancer 1, early onset isoform 5 [Homo sapiens] 54 7e-07
gi|237681123 breast cancer 1, early onset isoform 4 [Homo sapiens] 54 7e-07
gi|6552299 breast cancer 1, early onset isoform 1 [Homo sapiens] 54 7e-07
gi|68160937 tripartite motif-containing 25 [Homo sapiens] 53 9e-07
gi|187607085 ligand of numb-protein X 1 isoform a [Homo sapiens] 53 1e-06
gi|21630277 tripartite motif-containing 11 [Homo sapiens] 51 4e-06
gi|8923898 zinc finger protein 313 [Homo sapiens] 51 4e-06
gi|157426898 tripartite motif-containing 10 isoform 1 [Homo sapi... 51 4e-06
gi|157426896 tripartite motif-containing 10 isoform 2 [Homo sapi... 51 4e-06
gi|4504867 ring finger protein 8 isoform 1 [Homo sapiens] 51 5e-06
gi|7706091 bifunctional apoptosis regulator [Homo sapiens] 50 6e-06
gi|94536782 tripartite motif-containing 35 isoform 2 [Homo sapiens] 50 6e-06
gi|157743261 tripartite motif-containing 75 [Homo sapiens] 50 6e-06
gi|37655169 ring finger protein 135 isoform 2 [Homo sapiens] 50 8e-06
gi|37655167 ring finger protein 135 isoform 1 [Homo sapiens] 50 8e-06
gi|56605981 tripartite motif-containing 72 [Homo sapiens] 50 8e-06
gi|21359963 ring finger and WD repeat domain 2 isoform a [Homo s... 50 8e-06
gi|50233824 ring finger and WD repeat domain 2 isoform d24 [Homo... 50 8e-06
gi|109240538 polycomb group ring finger 1 [Homo sapiens] 50 1e-05
gi|54792146 tripartite motif-containing 47 [Homo sapiens] 50 1e-05
gi|115430235 ubiquitin-like with PHD and ring finger domains 1 i... 49 1e-05
gi|115430233 ubiquitin-like with PHD and ring finger domains 1 i... 49 1e-05
>gi|87080813 LON peptidase N-terminal domain and ring finger 1 [Homo
sapiens]
Length = 773
Score = 1578 bits (4086), Expect = 0.0
Identities = 773/773 (100%), Positives = 773/773 (100%)
Query: 1 MSSPAVARTSPGGSREMAPAPQGRGRFWEVGGGSGHRLERAAAESERWELLLRRGELLAL 60
MSSPAVARTSPGGSREMAPAPQGRGRFWEVGGGSGHRLERAAAESERWELLLRRGELLAL
Sbjct: 1 MSSPAVARTSPGGSREMAPAPQGRGRFWEVGGGSGHRLERAAAESERWELLLRRGELLAL 60
Query: 61 GGHLKGALEAFAAALRRGAPARPECLGALVDCLVFNYRLRHGLGWSAAPVAGADGGAGGL 120
GGHLKGALEAFAAALRRGAPARPECLGALVDCLVFNYRLRHGLGWSAAPVAGADGGAGGL
Sbjct: 61 GGHLKGALEAFAAALRRGAPARPECLGALVDCLVFNYRLRHGLGWSAAPVAGADGGAGGL 120
Query: 121 LRCLGCRGFLSEPVTVPCGHSYCRRCLRRELRARCRLCRDRLPPATASATDAEGTAPRPP 180
LRCLGCRGFLSEPVTVPCGHSYCRRCLRRELRARCRLCRDRLPPATASATDAEGTAPRPP
Sbjct: 121 LRCLGCRGFLSEPVTVPCGHSYCRRCLRRELRARCRLCRDRLPPATASATDAEGTAPRPP 180
Query: 181 PLAAAIAASDFRTSVVLNHLAEKWFPGQRERARAAGRLGELLHQGRYREALAAACEALRA 240
PLAAAIAASDFRTSVVLNHLAEKWFPGQRERARAAGRLGELLHQGRYREALAAACEALRA
Sbjct: 181 PLAAAIAASDFRTSVVLNHLAEKWFPGQRERARAAGRLGELLHQGRYREALAAACEALRA 240
Query: 241 EPSDLIVKIYRAESYAGLQEFKAAIEDLNAVLFQLPDWPEVYFRKGKVLCDAGFLGDALQ 300
EPSDLIVKIYRAESYAGLQEFKAAIEDLNAVLFQLPDWPEVYFRKGKVLCDAGFLGDALQ
Sbjct: 241 EPSDLIVKIYRAESYAGLQEFKAAIEDLNAVLFQLPDWPEVYFRKGKVLCDAGFLGDALQ 300
Query: 301 LFLQCLALDEDFAPAKLQVQKILCDLLLPENLKEGLKESSWSSLPCTKNRPFDFHSVMEE 360
LFLQCLALDEDFAPAKLQVQKILCDLLLPENLKEGLKESSWSSLPCTKNRPFDFHSVMEE
Sbjct: 301 LFLQCLALDEDFAPAKLQVQKILCDLLLPENLKEGLKESSWSSLPCTKNRPFDFHSVMEE 360
Query: 361 SQSLNEPSPKQSEEIPEVTSEPVKGSLNRAQSAQSINSTEMPAREDCLKRVSSEPVLSVQ 420
SQSLNEPSPKQSEEIPEVTSEPVKGSLNRAQSAQSINSTEMPAREDCLKRVSSEPVLSVQ
Sbjct: 361 SQSLNEPSPKQSEEIPEVTSEPVKGSLNRAQSAQSINSTEMPAREDCLKRVSSEPVLSVQ 420
Query: 421 EKGVLLKRKLSLLEQDVIVNEDGRNKLKKQGETPNEVCMFSLAYGDIPEELIDVSDFECS 480
EKGVLLKRKLSLLEQDVIVNEDGRNKLKKQGETPNEVCMFSLAYGDIPEELIDVSDFECS
Sbjct: 421 EKGVLLKRKLSLLEQDVIVNEDGRNKLKKQGETPNEVCMFSLAYGDIPEELIDVSDFECS 480
Query: 481 LCMRLFFEPVTTPCGHSFCKNCLERCLDHAPYCPLCKESLKEYLADRRYCVTQLLEELIV 540
LCMRLFFEPVTTPCGHSFCKNCLERCLDHAPYCPLCKESLKEYLADRRYCVTQLLEELIV
Sbjct: 481 LCMRLFFEPVTTPCGHSFCKNCLERCLDHAPYCPLCKESLKEYLADRRYCVTQLLEELIV 540
Query: 541 KYLPDELSERKKIYDEETAELSHLTKNVPIFVCTMAYPTVPCPLHVFEPRYRLMIRRSIQ 600
KYLPDELSERKKIYDEETAELSHLTKNVPIFVCTMAYPTVPCPLHVFEPRYRLMIRRSIQ
Sbjct: 541 KYLPDELSERKKIYDEETAELSHLTKNVPIFVCTMAYPTVPCPLHVFEPRYRLMIRRSIQ 600
Query: 601 TGTKQFGMCVSDTQNSFADYGCMLQIRNVHFLPDGRSVVDTVGGKRFRVLKRGMKDGYCT 660
TGTKQFGMCVSDTQNSFADYGCMLQIRNVHFLPDGRSVVDTVGGKRFRVLKRGMKDGYCT
Sbjct: 601 TGTKQFGMCVSDTQNSFADYGCMLQIRNVHFLPDGRSVVDTVGGKRFRVLKRGMKDGYCT 660
Query: 661 ADIEYLEDVKVENEDEIKNLRELHDLVYSQACSWFQNLRDRFRSQILQHFGSMPEREENL 720
ADIEYLEDVKVENEDEIKNLRELHDLVYSQACSWFQNLRDRFRSQILQHFGSMPEREENL
Sbjct: 661 ADIEYLEDVKVENEDEIKNLRELHDLVYSQACSWFQNLRDRFRSQILQHFGSMPEREENL 720
Query: 721 QAAPNGPAWCWWLLAVLPVDPRYQLSVLSMKSLKERLTKIQHILTYFSRDQSK 773
QAAPNGPAWCWWLLAVLPVDPRYQLSVLSMKSLKERLTKIQHILTYFSRDQSK
Sbjct: 721 QAAPNGPAWCWWLLAVLPVDPRYQLSVLSMKSLKERLTKIQHILTYFSRDQSK 773
>gi|148528975 LON peptidase N-terminal domain and ring finger 2
[Homo sapiens]
Length = 754
Score = 498 bits (1283), Expect = e-141
Identities = 305/739 (41%), Positives = 409/739 (55%), Gaps = 79/739 (10%)
Query: 50 LLLRRGELLALGGHLKGALEAFAAALRRGAPARPECL----GALVDCLVFNYRLRHGLGW 105
L LR G+ LA G L AL AF A R GA RPE L G LV + R
Sbjct: 60 LCLRLGDALARAGRLPEALGAFRGAARLGA-LRPEELEELAGGLVRAVGLRDRPLSAENP 118
Query: 106 SAAPVAGADGGAG-------GLLRCLGCRGFLSEPVTVPCGHSYCRRCLRRELRARCRLC 158
P A +GG LL C CR L +PVT+PCG + C+RC+
Sbjct: 119 GGEPEAPGEGGPAPEPRAPRDLLGCPRCRRLLHKPVTLPCGLTVCKRCVE---------- 168
Query: 159 RDRLPPATASATDAEGTAPRPPPLAAAIAASDFRTSVVLNHLAEKWFPGQRERARAAGRL 218
P P + R +VVL+ L EK FP + R AG+
Sbjct: 169 --------------------PGPARPQVR----RVNVVLSGLLEKCFPAECRLRRLAGQA 204
Query: 219 GELLHQGRYREALAAACEALRAEPSDLIVKIYRAESYAGLQEFKAAIEDLNAVLFQLPDW 278
L Q + AL +AL P D + + RAE Y ++ ++ A++D +A P
Sbjct: 205 RSLQRQQQPEAALLRCDQALELAPDDNSLLLLRAELYLTMKNYEQALQDASAACQNEPLL 264
Query: 279 PEVYFRKGKVLCDAGFLGDALQLFLQCLALDEDFAPAKLQVQKILCDLLLPE--NLKEGL 336
+ + K + L G + L+ FL CLAL+ + K + QK++C++L N+ E L
Sbjct: 265 IKGHQVKAQALSGLGRSKEVLKEFLYCLALNPECNSVKKEAQKVMCEVLFSATANVHENL 324
Query: 337 KESSWSSLPCTKNRPFDFHSVMEESQS-LNEPSPKQSEEIPEVTSEPVKG--SLNRAQSA 393
S S L + + +++EE + +E S ++S+ + S + L+ +
Sbjct: 325 TSSIQSRLKAQGHSHMNAQALLEEGDAGSSENSSEKSDMLGNTNSSVLYFILGLHFEEDK 384
Query: 394 QSINSTEMPAREDCLKRVSSEPVLSVQE---KGVLLKRKLSLLEQDVIVNEDGRNKLKKQ 450
+++ S A LKR + V + G + K+ LSL E+ Q
Sbjct: 385 KALESILPTAPSAGLKRQFPDDVEDAPDLNAPGKIPKKDLSLQRSPNSETEES------Q 438
Query: 451 GETPNEVCMFSLAYGDIPEELIDVSDFECSLCMRLFFEPVTTPCGHSFCKNCLERCLDHA 510
G + +DV+DFEC+LCMRL FEPVTTPCGH+FC CLERCLDHA
Sbjct: 439 GLS------------------LDVTDFECALCMRLLFEPVTTPCGHTFCLKCLERCLDHA 480
Query: 511 PYCPLCKESLKEYLADRRYCVTQLLEELIVKYLPDELSERKKIYDEETAELSHLTKNVPI 570
P+CPLCK+ L E LA R + +T L EELI +YLPDELS+RK+IYDEE +ELS+LT++VPI
Sbjct: 481 PHCPLCKDKLSELLASRNFNITVLAEELIFRYLPDELSDRKRIYDEEMSELSNLTRDVPI 540
Query: 571 FVCTMAYPTVPCPLHVFEPRYRLMIRRSIQTGTKQFGMCVSDTQNSFADYGCMLQIRNVH 630
FVC MA+PTVPCPLHVFEPRYRLMIRR ++TGTK+FGMC+S ++YGCML+I++V
Sbjct: 541 FVCAMAFPTVPCPLHVFEPRYRLMIRRCMETGTKRFGMCLSAEHAGLSEYGCMLEIKDVR 600
Query: 631 FLPDGRSVVDTVGGKRFRVLKRGMKDGYCTADIEYLEDVKVENEDEIKNLRELHDLVYSQ 690
PDG SVVD +G RFRVL +DGY TADIEYLED KVE E + L LHD V+ Q
Sbjct: 601 TFPDGSSVVDAIGISRFRVLSHRHRDGYNTADIEYLEDEKVEG-PEYEELAALHDSVHQQ 659
Query: 691 ACSWFQNLRDRFRSQILQHFGSMPEREENLQAAPNGPAWCWWLLAVLPVDPRYQLSVLSM 750
+ SWF +L+DR + QIL HFG MP+RE Q+ P+GPAW WW+LAVLP++ + QL++L M
Sbjct: 660 SVSWFASLQDRMKEQILSHFGVMPDREPEPQSNPSGPAWSWWILAVLPLERKAQLAILGM 719
Query: 751 KSLKERLTKIQHILTYFSR 769
SLKERL I+ IL +R
Sbjct: 720 TSLKERLLAIRRILVIITR 738
>gi|73747840 LON peptidase N-terminal domain and ring finger 3
isoform 1 [Homo sapiens]
Length = 759
Score = 496 bits (1277), Expect = e-140
Identities = 300/747 (40%), Positives = 407/747 (54%), Gaps = 78/747 (10%)
Query: 49 ELLLRRGELLALGGHLKGALEAFAAALRRGAPARPECLGALVDCLVFNYRLRHGL----- 103
++LL + + LA G ++ ALE + R E L LV CL L
Sbjct: 68 KVLLTQADALASRGRIREALEVYRQLSERQQLVA-EQLEQLVRCLAEKVPQGEALAPAPP 126
Query: 104 -------GWSAAPVAGADGGAGGL-----LRCLGCRGFLSEPVTVPCGHSYCRRCLRREL 151
G AA GA A +C C GFLS+PV++ CGH++C+ CL R
Sbjct: 127 DEGSTASGTVAAEETGAAAAAAATEVWDGFKCRKCHGFLSDPVSLSCGHTFCKLCLERGR 186
Query: 152 RA--RCRLCRDRLPP---ATASATDAEGTAPRPPPLAAAIAASDFRTSVVLNHLAEKWFP 206
A RC LC +L AT A A +PPP R +VVL+ L K FP
Sbjct: 187 AADRRCALCGVKLSALMVATGRARGARRAGQQPPP--------PLRVNVVLSGLLGKLFP 238
Query: 207 GQRERARAAGRLGELLHQGRYREALAAACEALRAEPSDLIVKIYRAESYAGLQEFKAAIE 266
G ++ L + + AL EA++ P+D ++ R++ Y L+ + A+
Sbjct: 239 GPARASQLRHEGNRLYRERQVEAALLKYNEAVKLAPNDHLLYSNRSQIYFTLESHENALH 298
Query: 267 DLNAVLFQLPDWPEVYFRKGKVLCDAGFLGDALQLFLQCLALDEDFAPAKLQVQKILCDL 326
D P + +FRK + L G + +AL+ FL C++LD A+ + Q+ +L
Sbjct: 299 DAEIACKLRPMGFKAHFRKAQALATLGKVEEALREFLYCVSLDGKNKRARCEAQRDNLEL 358
Query: 327 LLPENLKEGLKESSWSSLPCTKNRPFDFHSVMEESQSLNEPSPKQSEEIPEVTSEPVKGS 386
+ +E SSL D V + Q + ++ EE + TS
Sbjct: 359 PHCSSQEEAAARGDGSSL-------MDPAKVKGDGQQHHMKDQEEEEEKWDATSP----- 406
Query: 387 LNRAQSAQSINSTEMPAREDCLKRVSSEPVLSVQEKGVLLKRKLSLLEQDVIVNEDGR-N 445
+ +S QEK KRK +E E G N
Sbjct: 407 -----------------------KAASSKTGKCQEK----KRKHCQIESQ---EETGMPN 436
Query: 446 KLKKQGETPNEVCMFSLAYGDIPEELIDVSDFECSLCMRLFFEPVTTPCGHSFCKNCLER 505
K KQ ++ +L+ +P D SD EC+LCMRLF+EPVTTPCGH+FC CLER
Sbjct: 437 KASKQDPPTDQGDKPALS---LPLASFDASDLECALCMRLFYEPVTTPCGHTFCLKCLER 493
Query: 506 CLDHAPYCPLCKESLKEYLADRRYCVTQLLEELIVKYLPDELSERKKIYDEETAELSHLT 565
CLDH CPLCK+ L + LA R+Y ++EELI K+LP+EL ER+K+Y+EE ELS+L
Sbjct: 494 CLDHNAKCPLCKDGLSQCLASRKYSKNVIMEELIAKFLPEELKERRKLYEEEMEELSNLN 553
Query: 566 KNVPIFVCTMAYPTVPCPLHVFEPRYRLMIRRSIQTGTKQFGMCVSDTQNSFADYGCMLQ 625
KNVPIFVCTMAYPTVPCPLH+FEP YRLMIRR I+TGT+QFGMC+ D FA+YGC+L+
Sbjct: 554 KNVPIFVCTMAYPTVPCPLHIFEPCYRLMIRRCIETGTRQFGMCLGDPVKGFAEYGCILE 613
Query: 626 IRNVHFLPDGRSVVDTVGGKRFRVLKRGMKDGYCTADIEYLEDVKVENEDEIKNLRELHD 685
IRNV F DGRSVVD++G +RFRVL + +DGY TADIEY+ED KV+ ED L LH+
Sbjct: 614 IRNVQFFADGRSVVDSIGKRRFRVLHQSQRDGYNTADIEYIEDQKVQGED-CAELMGLHN 672
Query: 686 LVYSQACSWFQNLRDRFRSQILQHFGSMPEREENLQAAPNGPAWCWWLLAVLPVDPRYQL 745
VY QA WF +L+ +++IL HFG MPE++ + Q PNGPAWCWW+LAVLP++ R QL
Sbjct: 673 CVYQQASLWFHSLKLSLKNRILNHFGPMPEKDADPQMNPNGPAWCWWMLAVLPLESRAQL 732
Query: 746 SVLSMKSLKERLTKIQHILTYFSRDQS 772
L+M+SLK+RL I+ +L + SR+Q+
Sbjct: 733 PFLAMRSLKDRLNGIRRVLAFISRNQN 759
>gi|37622896 LON peptidase N-terminal domain and ring finger 3
isoform 2 [Homo sapiens]
Length = 718
Score = 409 bits (1052), Expect = e-114
Identities = 187/306 (61%), Positives = 236/306 (77%), Gaps = 1/306 (0%)
Query: 467 IPEELIDVSDFECSLCMRLFFEPVTTPCGHSFCKNCLERCLDHAPYCPLCKESLKEYLAD 526
+P D SD EC+LCMRLF+EPVTTPCGH+FC CLERCLDH CPLCK+ L + LA
Sbjct: 414 LPLASFDASDLECALCMRLFYEPVTTPCGHTFCLKCLERCLDHNAKCPLCKDGLSQCLAS 473
Query: 527 RRYCVTQLLEELIVKYLPDELSERKKIYDEETAELSHLTKNVPIFVCTMAYPTVPCPLHV 586
R+Y ++EELI K+LP+EL ER+K+Y+EE ELS+L KNVPIFVCTMAYPTVPCPLH+
Sbjct: 474 RKYSKNVIMEELIAKFLPEELKERRKLYEEEMEELSNLNKNVPIFVCTMAYPTVPCPLHI 533
Query: 587 FEPRYRLMIRRSIQTGTKQFGMCVSDTQNSFADYGCMLQIRNVHFLPDGRSVVDTVGGKR 646
FEP YRLMIRR I+TGT+QFGMC+ D FA+YGC+L+IRNV F DGRSVVD++G +R
Sbjct: 534 FEPCYRLMIRRCIETGTRQFGMCLGDPVKGFAEYGCILEIRNVQFFADGRSVVDSIGKRR 593
Query: 647 FRVLKRGMKDGYCTADIEYLEDVKVENEDEIKNLRELHDLVYSQACSWFQNLRDRFRSQI 706
FRVL + +DGY TADIEY+ED KV+ ED L LH+ VY QA WF +L+ +++I
Sbjct: 594 FRVLHQSQRDGYNTADIEYIEDQKVQGED-CAELMGLHNCVYQQASLWFHSLKLSLKNRI 652
Query: 707 LQHFGSMPEREENLQAAPNGPAWCWWLLAVLPVDPRYQLSVLSMKSLKERLTKIQHILTY 766
L HFG MPE++ + Q PNGPAWCWW+LAVLP++ R QL L+M+SLK+RL I+ +L +
Sbjct: 653 LNHFGPMPEKDADPQMNPNGPAWCWWMLAVLPLESRAQLPFLAMRSLKDRLNGIRRVLAF 712
Query: 767 FSRDQS 772
SR+Q+
Sbjct: 713 ISRNQN 718
Score = 84.0 bits (206), Expect = 5e-16
Identities = 71/241 (29%), Positives = 103/241 (42%), Gaps = 31/241 (12%)
Query: 49 ELLLRRGELLALGGHLKGALEAFAAALRRGAPARPECLGALVDCLVFNYRLRHGL----- 103
++LL + + LA G ++ ALE + R E L LV CL L
Sbjct: 68 KVLLTQADALASRGRIREALEVYRQLSERQQLVA-EQLEQLVRCLAEKVPQGEALAPAPP 126
Query: 104 -------GWSAAPVAGADGGAGGL-----LRCLGCRGFLSEPVTVPCGHSYCRRCLRREL 151
G AA GA A +C C GFLS+PV++ CGH++C+ CL R
Sbjct: 127 DEGSTASGTVAAEETGAAAAAAATEVWDGFKCRKCHGFLSDPVSLSCGHTFCKLCLERGR 186
Query: 152 RA--RCRLCRDRLPP---ATASATDAEGTAPRPPPLAAAIAASDFRTSVVLNHLAEKWFP 206
A RC LC +L AT A A +PPP R +VVL+ L K FP
Sbjct: 187 AADRRCALCGVKLSALMVATGRARGARRAGQQPPP--------PLRVNVVLSGLLGKLFP 238
Query: 207 GQRERARAAGRLGELLHQGRYREALAAACEALRAEPSDLIVKIYRAESYAGLQEFKAAIE 266
G ++ L + + AL EA++ P+D ++ R++ Y L+ + A+
Sbjct: 239 GPARASQLRHEGNRLYRERQVEAALLKYNEAVKLAPNDHLLYSNRSQIYFTLESHENALH 298
Query: 267 D 267
D
Sbjct: 299 D 299
Score = 51.6 bits (122), Expect = 3e-06
Identities = 24/50 (48%), Positives = 29/50 (58%), Gaps = 2/50 (4%)
Query: 121 LRCLGCRGFLSEPVTVPCGHSYCRRCLRREL--RARCRLCRDRLPPATAS 168
L C C EPVT PCGH++C +CL R L A+C LC+D L AS
Sbjct: 424 LECALCMRLFYEPVTTPCGHTFCLKCLERCLDHNAKCPLCKDGLSQCLAS 473
Score = 42.4 bits (98), Expect = 0.002
Identities = 18/40 (45%), Positives = 22/40 (55%)
Query: 477 FECSLCMRLFFEPVTTPCGHSFCKNCLERCLDHAPYCPLC 516
F+C C +PV+ CGH+FCK CLER C LC
Sbjct: 156 FKCRKCHGFLSDPVSLSCGHTFCKLCLERGRAADRRCALC 195
>gi|224028289 tetratricopeptide repeat domain 28 [Homo sapiens]
Length = 2481
Score = 55.8 bits (133), Expect = 1e-07
Identities = 40/161 (24%), Positives = 68/161 (42%), Gaps = 6/161 (3%)
Query: 177 PRPPPLAAAIAASDFRTSVVLNHLAEKWFPGQRERARAAGRLGELLHQGRYREALAAACE 236
P PP +A I F + + + E + + H G + A+ E
Sbjct: 26 PESPPASAPIPL--FGADTIGQRSPDGPVLSKAEFVEKVRQSNQACHDGDFHTAIVLYNE 83
Query: 237 ALRAEPSDLIVKIYRAESYAGLQEFKAAIEDLNAVLFQLPDWPEVYFRKGKVLCDAGFLG 296
AL +P + I+ R+ +Y +Q++ A++D P WP+ YFR+G L G
Sbjct: 84 ALAVDPQNCILYSNRSAAYMKIQQYDKALDDAIKARLLNPKWPKAYFRQGVALQYLGRHA 143
Query: 297 DALQLFLQCLALDEDFAPAKLQVQKILCDLLLPENLKEGLK 337
DAL F LA D P LQ+ + + + +++ L+
Sbjct: 144 DALAAFASGLAQD----PKSLQLLVGMVEAAMKSPMRDSLE 180
>gi|31377566 ring finger protein 168 [Homo sapiens]
Length = 571
Score = 55.8 bits (133), Expect = 1e-07
Identities = 31/96 (32%), Positives = 47/96 (48%), Gaps = 5/96 (5%)
Query: 467 IPEELI-DVSDFECSLCMRLFFEPVTTPCGHSFCKNCLERCLDHAPY-CPLCK---ESLK 521
+P++ I +S+ +C +CM + EPVT PC H+ CK C + ++ A CP C+ S
Sbjct: 3 LPKDAIPSLSECQCGICMEILVEPVTLPCNHTLCKPCFQSTVEKASLCCPFCRRRVSSWT 62
Query: 522 EYLADRRYCVTQLLEELIVKYLPDELSERKKIYDEE 557
Y R V L +I K+ P E R + E
Sbjct: 63 RYHTRRNSLVNVELWTIIQKHYPRECKLRASGQESE 98
Score = 37.0 bits (84), Expect = 0.070
Identities = 37/154 (24%), Positives = 61/154 (39%), Gaps = 21/154 (13%)
Query: 122 RCLGCRGFLSEPVTVPCGHSYCRRCLRRELRAR---CRLCRDRLPPATASATDAEGTAPR 178
+C C L EPVT+PC H+ C+ C + + C CR R+ T T
Sbjct: 15 QCGICMEILVEPVTLPCNHTLCKPCFQSTVEKASLCCPFCRRRVSSWTRYHTRRNSL--- 71
Query: 179 PPPLAAAIAASDFRTSVVLNHLAEKWFPGQRERARAAGRLGELLHQGRYREALAAACEAL 238
+V L + +K +P + + RA+G+ E + L + L
Sbjct: 72 --------------VNVELWTIIQKHYP-RECKLRASGQESEEVADDYQPVRLLSKPGEL 116
Query: 239 RAEPSDLIVKIYRAESYAGLQEFKAAIEDLNAVL 272
R E + I K+ + +E KA+ E + +L
Sbjct: 117 RREYEEEISKVAAERRASEEEENKASEEYIQRLL 150
>gi|24025688 ligand of numb-protein X 2 [Homo sapiens]
Length = 690
Score = 53.9 bits (128), Expect = 6e-07
Identities = 24/66 (36%), Positives = 38/66 (57%), Gaps = 1/66 (1%)
Query: 476 DFECSLCMRLFFEPVTTPCGHSFCKNCLERCLDHAPYCPLCKESLKEYLADR-RYCVTQL 534
D C +C++ +P+ TPCGH+FC CL L +CPL ++ L L + V +L
Sbjct: 47 DLVCHICLQPLLQPLDTPCGHTFCYKCLRNFLQEKDFCPLDRKRLHFKLCKKSSILVHKL 106
Query: 535 LEELIV 540
L++L+V
Sbjct: 107 LDKLLV 112
Score = 38.1 bits (87), Expect = 0.031
Identities = 19/44 (43%), Positives = 26/44 (59%), Gaps = 2/44 (4%)
Query: 121 LRCLGCRGFLSEPVTVPCGHSYCRRCLRRELRAR--CRLCRDRL 162
L C C L +P+ PCGH++C +CLR L+ + C L R RL
Sbjct: 48 LVCHICLQPLLQPLDTPCGHTFCYKCLRNFLQEKDFCPLDRKRL 91
>gi|237681119 breast cancer 1, early onset isoform 2 [Homo sapiens]
Length = 1884
Score = 53.5 bits (127), Expect = 7e-07
Identities = 25/65 (38%), Positives = 36/65 (55%), Gaps = 3/65 (4%)
Query: 478 ECSLCMRLFFEPVTTPCGHSFCKNCLERCLDH---APYCPLCKESLKEYLADRRYCVTQL 534
EC +C+ L EPV+T C H FCK C+ + L+ CPLCK + + +QL
Sbjct: 23 ECPICLELIKEPVSTKCDHIFCKFCMLKLLNQKKGPSQCPLCKNDITKRSLQESTRFSQL 82
Query: 535 LEELI 539
+EEL+
Sbjct: 83 VEELL 87
Score = 34.3 bits (77), Expect = 0.45
Identities = 14/46 (30%), Positives = 25/46 (54%), Gaps = 5/46 (10%)
Query: 120 LLRCLGCRGFLSEPVTVPCGHSYCRRCLRRELR-----ARCRLCRD 160
+L C C + EPV+ C H +C+ C+ + L ++C LC++
Sbjct: 21 ILECPICLELIKEPVSTKCDHIFCKFCMLKLLNQKKGPSQCPLCKN 66
>gi|237681125 breast cancer 1, early onset isoform 5 [Homo sapiens]
Length = 699
Score = 53.5 bits (127), Expect = 7e-07
Identities = 25/65 (38%), Positives = 36/65 (55%), Gaps = 3/65 (4%)
Query: 478 ECSLCMRLFFEPVTTPCGHSFCKNCLERCLDH---APYCPLCKESLKEYLADRRYCVTQL 534
EC +C+ L EPV+T C H FCK C+ + L+ CPLCK + + +QL
Sbjct: 23 ECPICLELIKEPVSTKCDHIFCKFCMLKLLNQKKGPSQCPLCKNDITKRSLQESTRFSQL 82
Query: 535 LEELI 539
+EEL+
Sbjct: 83 VEELL 87
Score = 34.3 bits (77), Expect = 0.45
Identities = 14/46 (30%), Positives = 25/46 (54%), Gaps = 5/46 (10%)
Query: 120 LLRCLGCRGFLSEPVTVPCGHSYCRRCLRRELR-----ARCRLCRD 160
+L C C + EPV+ C H +C+ C+ + L ++C LC++
Sbjct: 21 ILECPICLELIKEPVSTKCDHIFCKFCMLKLLNQKKGPSQCPLCKN 66
>gi|237681123 breast cancer 1, early onset isoform 4 [Homo sapiens]
Length = 759
Score = 53.5 bits (127), Expect = 7e-07
Identities = 25/65 (38%), Positives = 36/65 (55%), Gaps = 3/65 (4%)
Query: 478 ECSLCMRLFFEPVTTPCGHSFCKNCLERCLDH---APYCPLCKESLKEYLADRRYCVTQL 534
EC +C+ L EPV+T C H FCK C+ + L+ CPLCK + + +QL
Sbjct: 23 ECPICLELIKEPVSTKCDHIFCKFCMLKLLNQKKGPSQCPLCKNDITKRSLQESTRFSQL 82
Query: 535 LEELI 539
+EEL+
Sbjct: 83 VEELL 87
Score = 34.3 bits (77), Expect = 0.45
Identities = 14/46 (30%), Positives = 25/46 (54%), Gaps = 5/46 (10%)
Query: 120 LLRCLGCRGFLSEPVTVPCGHSYCRRCLRRELR-----ARCRLCRD 160
+L C C + EPV+ C H +C+ C+ + L ++C LC++
Sbjct: 21 ILECPICLELIKEPVSTKCDHIFCKFCMLKLLNQKKGPSQCPLCKN 66
>gi|6552299 breast cancer 1, early onset isoform 1 [Homo sapiens]
Length = 1863
Score = 53.5 bits (127), Expect = 7e-07
Identities = 25/65 (38%), Positives = 36/65 (55%), Gaps = 3/65 (4%)
Query: 478 ECSLCMRLFFEPVTTPCGHSFCKNCLERCLDH---APYCPLCKESLKEYLADRRYCVTQL 534
EC +C+ L EPV+T C H FCK C+ + L+ CPLCK + + +QL
Sbjct: 23 ECPICLELIKEPVSTKCDHIFCKFCMLKLLNQKKGPSQCPLCKNDITKRSLQESTRFSQL 82
Query: 535 LEELI 539
+EEL+
Sbjct: 83 VEELL 87
Score = 34.3 bits (77), Expect = 0.45
Identities = 14/46 (30%), Positives = 25/46 (54%), Gaps = 5/46 (10%)
Query: 120 LLRCLGCRGFLSEPVTVPCGHSYCRRCLRRELR-----ARCRLCRD 160
+L C C + EPV+ C H +C+ C+ + L ++C LC++
Sbjct: 21 ILECPICLELIKEPVSTKCDHIFCKFCMLKLLNQKKGPSQCPLCKN 66
>gi|68160937 tripartite motif-containing 25 [Homo sapiens]
Length = 630
Score = 53.1 bits (126), Expect = 9e-07
Identities = 22/45 (48%), Positives = 30/45 (66%), Gaps = 3/45 (6%)
Query: 476 DFECSLCMRLFFEPVTTPCGHSFCKNCLER--CLDHAPY-CPLCK 517
+ CS+C+ F EPVTTPCGH+FC +CL + +PY CP C+
Sbjct: 10 ELSCSICLEPFKEPVTTPCGHNFCGSCLNETWAVQGSPYLCPQCR 54
Score = 35.8 bits (81), Expect = 0.16
Identities = 14/27 (51%), Positives = 16/27 (59%)
Query: 121 LRCLGCRGFLSEPVTVPCGHSYCRRCL 147
L C C EPVT PCGH++C CL
Sbjct: 11 LSCSICLEPFKEPVTTPCGHNFCGSCL 37
>gi|187607085 ligand of numb-protein X 1 isoform a [Homo sapiens]
Length = 728
Score = 52.8 bits (125), Expect = 1e-06
Identities = 25/74 (33%), Positives = 42/74 (56%), Gaps = 3/74 (4%)
Query: 468 PEELIDVSDFECSLCMRLFFEPVTTPCGHSFCKNCLERCLDHAPYCPLCKESL-KEYLAD 526
PEE+ D D C +C++ +P+ TPCGH++C CL L +CP+ ++ L ++
Sbjct: 32 PEEVDD--DLICHICLQALLDPLDTPCGHTYCTLCLTNFLVEKDFCPMDRKPLVLQHCKK 89
Query: 527 RRYCVTQLLEELIV 540
V +LL +L+V
Sbjct: 90 SSILVNKLLNKLLV 103
Score = 34.3 bits (77), Expect = 0.45
Identities = 17/43 (39%), Positives = 21/43 (48%)
Query: 121 LRCLGCRGFLSEPVTVPCGHSYCRRCLRRELRARCRLCRDRLP 163
L C C L +P+ PCGH+YC CL L + DR P
Sbjct: 39 LICHICLQALLDPLDTPCGHTYCTLCLTNFLVEKDFCPMDRKP 81
>gi|21630277 tripartite motif-containing 11 [Homo sapiens]
Length = 468
Score = 51.2 bits (121), Expect = 4e-06
Identities = 20/43 (46%), Positives = 28/43 (65%), Gaps = 3/43 (6%)
Query: 479 CSLCMRLFFEPVTTPCGHSFCKNCLERC--LDHAPY-CPLCKE 518
C++C+ F +PV T CGH+FC+ C+ RC PY CP C+E
Sbjct: 16 CAICLDYFTDPVMTDCGHNFCRECIRRCWGQPEGPYACPECRE 58
Score = 39.3 bits (90), Expect = 0.014
Identities = 17/46 (36%), Positives = 24/46 (52%), Gaps = 5/46 (10%)
Query: 123 CLGCRGFLSEPVTVPCGHSYCRRCLRR-----ELRARCRLCRDRLP 163
C C + ++PV CGH++CR C+RR E C CR+ P
Sbjct: 16 CAICLDYFTDPVMTDCGHNFCRECIRRCWGQPEGPYACPECRELSP 61
>gi|8923898 zinc finger protein 313 [Homo sapiens]
Length = 228
Score = 51.2 bits (121), Expect = 4e-06
Identities = 19/45 (42%), Positives = 28/45 (62%), Gaps = 1/45 (2%)
Query: 477 FECSLCMRLFFEPVTTPCGHSFCKNCLERCL-DHAPYCPLCKESL 520
F C +C+ ++ +PV PCGH FC CL+ CL P C +C+ +L
Sbjct: 27 FTCPVCLEVYEKPVQVPCGHVFCSACLQECLKPKKPVCGVCRSAL 71
Score = 43.9 bits (102), Expect = 6e-04
Identities = 25/66 (37%), Positives = 31/66 (46%), Gaps = 5/66 (7%)
Query: 102 GLGWSAAPVAGADGGAGGLLRCLGCRGFLSEPVTVPCGHSYCRRCLRRELRAR---CRLC 158
G A P A AD G C C +PV VPCGH +C CL+ L+ + C +C
Sbjct: 10 GAAQLAGPAAEAD--PLGRFTCPVCLEVYEKPVQVPCGHVFCSACLQECLKPKKPVCGVC 67
Query: 159 RDRLPP 164
R L P
Sbjct: 68 RSALAP 73
>gi|157426898 tripartite motif-containing 10 isoform 1 [Homo
sapiens]
Length = 481
Score = 51.2 bits (121), Expect = 4e-06
Identities = 22/53 (41%), Positives = 29/53 (54%), Gaps = 7/53 (13%)
Query: 476 DFECSLCMRLFFEPVTTPCGHSFCKNCLERC-------LDHAPYCPLCKESLK 521
+ C +C EPVT CGH+FC+ CL R L+ +P CPLCKE +
Sbjct: 13 EVNCPICQGTLREPVTIDCGHNFCRACLTRYCEIPGPDLEESPTCPLCKEPFR 65
Score = 45.8 bits (107), Expect = 1e-04
Identities = 21/55 (38%), Positives = 29/55 (52%), Gaps = 9/55 (16%)
Query: 121 LRCLGCRGFLSEPVTVPCGHSYCRRCLRR---------ELRARCRLCRDRLPPAT 166
+ C C+G L EPVT+ CGH++CR CL R E C LC++ P +
Sbjct: 14 VNCPICQGTLREPVTIDCGHNFCRACLTRYCEIPGPDLEESPTCPLCKEPFRPGS 68
>gi|157426896 tripartite motif-containing 10 isoform 2 [Homo
sapiens]
Length = 395
Score = 51.2 bits (121), Expect = 4e-06
Identities = 22/53 (41%), Positives = 29/53 (54%), Gaps = 7/53 (13%)
Query: 476 DFECSLCMRLFFEPVTTPCGHSFCKNCLERC-------LDHAPYCPLCKESLK 521
+ C +C EPVT CGH+FC+ CL R L+ +P CPLCKE +
Sbjct: 13 EVNCPICQGTLREPVTIDCGHNFCRACLTRYCEIPGPDLEESPTCPLCKEPFR 65
Score = 45.8 bits (107), Expect = 1e-04
Identities = 21/55 (38%), Positives = 29/55 (52%), Gaps = 9/55 (16%)
Query: 121 LRCLGCRGFLSEPVTVPCGHSYCRRCLRR---------ELRARCRLCRDRLPPAT 166
+ C C+G L EPVT+ CGH++CR CL R E C LC++ P +
Sbjct: 14 VNCPICQGTLREPVTIDCGHNFCRACLTRYCEIPGPDLEESPTCPLCKEPFRPGS 68
>gi|4504867 ring finger protein 8 isoform 1 [Homo sapiens]
Length = 485
Score = 50.8 bits (120), Expect = 5e-06
Identities = 41/171 (23%), Positives = 76/171 (44%), Gaps = 15/171 (8%)
Query: 391 QSAQSINSTEMPAREDCLKRVSSEPVLSVQEKGVLLKRKLSLLEQDVIVNEDGRNKLKKQ 450
+ Q + E+ E LK+ ++ ++QE L++ +L+ ++D +NK +Q
Sbjct: 319 EEEQHLQGLEIAQGEKDLKQQLAQ---ALQEHWALME-ELNRSKKDFEAIIQAKNKELEQ 374
Query: 451 GETPNEVCMFSLAYGDIPEELIDV--SDFECSLCMRLFFEPVTTPCGHSFCKNCLERCLD 508
T E ++ + DV ++ +C +C F E VT C HSFC C+ +
Sbjct: 375 --TKEEKEKMQAQKEEVLSHMNDVLENELQCIICSEYFIEAVTLNCAHSFCSYCINEWMK 432
Query: 509 HAPYCPLCKESLKE--YLADRRYCVTQLLEELIVKYLPDELSERKKIYDEE 557
CP+C++ +K Y C+ ++ V L E+ ER+ + E
Sbjct: 433 RKIECPICRKDIKSKTYSLVLDNCINKM-----VNNLSSEVKERRIVLIRE 478
Score = 38.1 bits (87), Expect = 0.031
Identities = 16/50 (32%), Positives = 27/50 (54%), Gaps = 2/50 (4%)
Query: 121 LRCLGCRGFLSEPVTVPCGHSYCRRCLRRELRAR--CRLCRDRLPPATAS 168
L+C+ C + E VT+ C HS+C C+ ++ + C +CR + T S
Sbjct: 401 LQCIICSEYFIEAVTLNCAHSFCSYCINEWMKRKIECPICRKDIKSKTYS 450
>gi|7706091 bifunctional apoptosis regulator [Homo sapiens]
Length = 450
Score = 50.4 bits (119), Expect = 6e-06
Identities = 28/81 (34%), Positives = 38/81 (46%), Gaps = 7/81 (8%)
Query: 472 IDVSDFECSLCMRLFFEPVTTPCGHSFCKNCLER--CLDHAPYCPLCKESLKEYLADRRY 529
I VS+F C C + P T CGHSFC++CL CP C+E + +
Sbjct: 27 ISVSEFSCHCCYDILVNPTTLNCGHSFCRHCLALWWASSKKTECPECREKWEGFPK---- 82
Query: 530 CVTQLLEELIVKYLPDELSER 550
V+ LL + I K PD + R
Sbjct: 83 -VSILLRDAIEKLFPDAIRLR 102
Score = 37.0 bits (84), Expect = 0.070
Identities = 16/43 (37%), Positives = 21/43 (48%), Gaps = 4/43 (9%)
Query: 123 CLGCRGFLSEPVTVPCGHSYCRRCL----RRELRARCRLCRDR 161
C C L P T+ CGHS+CR CL + C CR++
Sbjct: 34 CHCCYDILVNPTTLNCGHSFCRHCLALWWASSKKTECPECREK 76
>gi|94536782 tripartite motif-containing 35 isoform 2 [Homo sapiens]
Length = 493
Score = 50.4 bits (119), Expect = 6e-06
Identities = 21/63 (33%), Positives = 36/63 (57%), Gaps = 2/63 (3%)
Query: 479 CSLCMRLFFEPVTTPCGHSFCKNCLERC--LDHAPYCPLCKESLKEYLADRRYCVTQLLE 536
C++C F + VT CGH+FC+ C+ RC + +P CP+CK+ + + L+E
Sbjct: 21 CAVCYDPFRDAVTLRCGHNFCRGCVSRCWEVQVSPTCPVCKDRASPADLRTNHTLNNLVE 80
Query: 537 ELI 539
+L+
Sbjct: 81 KLL 83
Score = 47.4 bits (111), Expect = 5e-05
Identities = 37/131 (28%), Positives = 56/131 (42%), Gaps = 38/131 (29%)
Query: 121 LRCLGCRGFLSEPVTVPCGHSYCRRCLRR----ELRARCRLCRDRLPPATASATDAEGTA 176
L C C + VT+ CGH++CR C+ R ++ C +C+DR PA
Sbjct: 19 LLCAVCYDPFRDAVTLRCGHNFCRGCVSRCWEVQVSPTCPVCKDRASPA----------- 67
Query: 177 PRPPPLAAAIAASDFRTSVVLNHLAEKWFPGQRERAR-AAGRLGEL--LHQGRY------ 227
D RT+ LN+L EK + E AR + R + LH+G+
Sbjct: 68 -------------DLRTNHTLNNLVEKLLREEAEGARWTSYRFSRVCRLHRGQLSLFCLE 114
Query: 228 -REALAAACEA 237
+E L +C+A
Sbjct: 115 DKELLCCSCQA 125
>gi|157743261 tripartite motif-containing 75 [Homo sapiens]
Length = 468
Score = 50.4 bits (119), Expect = 6e-06
Identities = 34/121 (28%), Positives = 59/121 (48%), Gaps = 9/121 (7%)
Query: 475 SDFECSLCMRLFFEPVTTPCGHSFCKNCLERC---LDHAPYCPLCKESLKEYLADRRYCV 531
++ +CS+C+ +PVT CGH+FC++C+++ L CP+C+ +E +
Sbjct: 12 AEAKCSICLDYLSDPVTIECGHNFCRSCIQQSWLDLQELFPCPVCRHQCQEGHFRSNTQL 71
Query: 532 TQLLEELIVKYLPDELSERKKIYDEETAELSHLTKNVPIFVCTMAYPTVPCPLHVFEPRY 591
+++E I K L S ++K +E T H N P+ V V CPL P +
Sbjct: 72 GRMIE--IAKLLQSTKSNKRK-QEETTLCEKH---NQPLSVFCKEDLMVLCPLCTQPPDH 125
Query: 592 R 592
+
Sbjct: 126 Q 126
Score = 43.1 bits (100), Expect = 0.001
Identities = 17/40 (42%), Positives = 26/40 (65%)
Query: 110 VAGADGGAGGLLRCLGCRGFLSEPVTVPCGHSYCRRCLRR 149
VA A G +C C +LS+PVT+ CGH++CR C+++
Sbjct: 3 VAAALTGLQAEAKCSICLDYLSDPVTIECGHNFCRSCIQQ 42
>gi|37655169 ring finger protein 135 isoform 2 [Homo sapiens]
Length = 210
Score = 50.1 bits (118), Expect = 8e-06
Identities = 39/115 (33%), Positives = 50/115 (43%), Gaps = 34/115 (29%)
Query: 102 GLGWSAAPVAGADGGAGGLLRCLGCRGFLSEPVTVPCGHSYCRRCL------RRELRARC 155
GLG SA PV A+ G C+ C+G L P T+PCGHS+CR CL R R C
Sbjct: 5 GLG-SAVPVWLAEDDLG----CIICQGLLDWPATLPCGHSFCRHCLEALWGARDARRWAC 59
Query: 156 RLCRDRLPPATASATDAEGTAPRPPPLAAAIAASDFRTSVVLNHLAEKWFPGQRE 210
CR +G A +P R + +L LA+K+ RE
Sbjct: 60 PTCR-------------QGAAQQP----------HLRKNTLLQDLADKYRRAARE 91
Score = 46.6 bits (109), Expect = 9e-05
Identities = 28/88 (31%), Positives = 38/88 (43%), Gaps = 7/88 (7%)
Query: 459 MFSLAYGDIPEELIDVSDFECSLCMRLFFEPVTTPCGHSFCKNCLERCLDHAP----YCP 514
M L G + D C +C L P T PCGHSFC++CLE CP
Sbjct: 1 MAGLGLGSAVPVWLAEDDLGCIICQGLLDWPATLPCGHSFCRHCLEALWGARDARRWACP 60
Query: 515 LCKESLKEYLADRRYCVTQLLEELIVKY 542
C++ + R+ LL++L KY
Sbjct: 61 TCRQGAAQQPHLRK---NTLLQDLADKY 85
>gi|37655167 ring finger protein 135 isoform 1 [Homo sapiens]
Length = 432
Score = 50.1 bits (118), Expect = 8e-06
Identities = 39/115 (33%), Positives = 50/115 (43%), Gaps = 34/115 (29%)
Query: 102 GLGWSAAPVAGADGGAGGLLRCLGCRGFLSEPVTVPCGHSYCRRCL------RRELRARC 155
GLG SA PV A+ G C+ C+G L P T+PCGHS+CR CL R R C
Sbjct: 5 GLG-SAVPVWLAEDDLG----CIICQGLLDWPATLPCGHSFCRHCLEALWGARDARRWAC 59
Query: 156 RLCRDRLPPATASATDAEGTAPRPPPLAAAIAASDFRTSVVLNHLAEKWFPGQRE 210
CR +G A +P R + +L LA+K+ RE
Sbjct: 60 PTCR-------------QGAAQQP----------HLRKNTLLQDLADKYRRAARE 91
Score = 46.6 bits (109), Expect = 9e-05
Identities = 28/88 (31%), Positives = 38/88 (43%), Gaps = 7/88 (7%)
Query: 459 MFSLAYGDIPEELIDVSDFECSLCMRLFFEPVTTPCGHSFCKNCLERCLDHAP----YCP 514
M L G + D C +C L P T PCGHSFC++CLE CP
Sbjct: 1 MAGLGLGSAVPVWLAEDDLGCIICQGLLDWPATLPCGHSFCRHCLEALWGARDARRWACP 60
Query: 515 LCKESLKEYLADRRYCVTQLLEELIVKY 542
C++ + R+ LL++L KY
Sbjct: 61 TCRQGAAQQPHLRK---NTLLQDLADKY 85
>gi|56605981 tripartite motif-containing 72 [Homo sapiens]
Length = 477
Score = 50.1 bits (118), Expect = 8e-06
Identities = 24/68 (35%), Positives = 33/68 (48%), Gaps = 5/68 (7%)
Query: 476 DFECSLCMRLFFEPVTTPCGHSFCKNCL-----ERCLDHAPYCPLCKESLKEYLADRRYC 530
+ C LC++LF PVT CGHSFC+ CL E D CP C+ +
Sbjct: 11 ELSCPLCLQLFDAPVTAECGHSFCRACLGRVAGEPAADGTVLCPCCQAPTRPQALSTNLQ 70
Query: 531 VTQLLEEL 538
+ +L+E L
Sbjct: 71 LARLVEGL 78
Score = 36.6 bits (83), Expect = 0.091
Identities = 15/29 (51%), Positives = 16/29 (55%)
Query: 121 LRCLGCRGFLSEPVTVPCGHSYCRRCLRR 149
L C C PVT CGHS+CR CL R
Sbjct: 12 LSCPLCLQLFDAPVTAECGHSFCRACLGR 40
>gi|21359963 ring finger and WD repeat domain 2 isoform a [Homo
sapiens]
Length = 731
Score = 50.1 bits (118), Expect = 8e-06
Identities = 27/90 (30%), Positives = 45/90 (50%), Gaps = 13/90 (14%)
Query: 475 SDFECSLCMRLFFEPVTTPCGHSFCKNCLERCLDHAPYCPLCKESLKEYLADRRYCVTQL 534
+DF C +C + E T CGHSFC C+ + L+ CP C Y+ D
Sbjct: 132 NDFVCPICFDMIEEAYMTKCGHSFCYKCIHQSLEDNNRCPKC-----NYVVDN------- 179
Query: 535 LEELIVKYLPDEL-SERKKIYDEETAELSH 563
++ L +L +EL ++K+ ++E+ +L H
Sbjct: 180 IDHLYPNFLVNELILKQKQRFEEKRFKLDH 209
Score = 31.2 bits (69), Expect = 3.8
Identities = 13/38 (34%), Positives = 18/38 (47%), Gaps = 2/38 (5%)
Query: 123 CLGCRGFLSEPVTVPCGHSYCRRCLRREL--RARCRLC 158
C C + E CGHS+C +C+ + L RC C
Sbjct: 136 CPICFDMIEEAYMTKCGHSFCYKCIHQSLEDNNRCPKC 173
>gi|50233824 ring finger and WD repeat domain 2 isoform d24 [Homo
sapiens]
Length = 707
Score = 50.1 bits (118), Expect = 8e-06
Identities = 27/90 (30%), Positives = 45/90 (50%), Gaps = 13/90 (14%)
Query: 475 SDFECSLCMRLFFEPVTTPCGHSFCKNCLERCLDHAPYCPLCKESLKEYLADRRYCVTQL 534
+DF C +C + E T CGHSFC C+ + L+ CP C Y+ D
Sbjct: 132 NDFVCPICFDMIEEAYMTKCGHSFCYKCIHQSLEDNNRCPKC-----NYVVDN------- 179
Query: 535 LEELIVKYLPDEL-SERKKIYDEETAELSH 563
++ L +L +EL ++K+ ++E+ +L H
Sbjct: 180 IDHLYPNFLVNELILKQKQRFEEKRFKLDH 209
Score = 31.2 bits (69), Expect = 3.8
Identities = 13/38 (34%), Positives = 18/38 (47%), Gaps = 2/38 (5%)
Query: 123 CLGCRGFLSEPVTVPCGHSYCRRCLRREL--RARCRLC 158
C C + E CGHS+C +C+ + L RC C
Sbjct: 136 CPICFDMIEEAYMTKCGHSFCYKCIHQSLEDNNRCPKC 173
>gi|109240538 polycomb group ring finger 1 [Homo sapiens]
Length = 259
Score = 49.7 bits (117), Expect = 1e-05
Identities = 24/77 (31%), Positives = 43/77 (55%), Gaps = 2/77 (2%)
Query: 479 CSLCMRLFFEPVT-TPCGHSFCKNCLERCLDHAPYCPLCKESLKEYLADRRYCVTQLLEE 537
C LC F + T T C H+FCK+C+ + L + YCP+C + E + +++++
Sbjct: 47 CCLCAGYFVDATTITECLHTFCKSCIVKYLQTSKYCPMCNIKIHETQPLLNLKLDRVMQD 106
Query: 538 LIVKYLPD-ELSERKKI 553
++ K +P + SE K+I
Sbjct: 107 IVYKLVPGLQDSEEKRI 123
>gi|54792146 tripartite motif-containing 47 [Homo sapiens]
Length = 638
Score = 49.7 bits (117), Expect = 1e-05
Identities = 26/72 (36%), Positives = 37/72 (51%), Gaps = 12/72 (16%)
Query: 477 FECSLCMRLFFEPVTTPCGHSFCKNCLERCLDH-----------APYCPLCKESLKEYLA 525
F C +C+ EPVT PCGH+FC CL H A CPLC+E + L
Sbjct: 7 FSCPICLEPLREPVTLPCGHNFCLACLGALWPHRGASGAGGPGGAARCPLCQEPFPDGLQ 66
Query: 526 DRR-YCVTQLLE 536
R+ + +++LL+
Sbjct: 67 LRKNHTLSELLQ 78
Score = 38.1 bits (87), Expect = 0.031
Identities = 21/58 (36%), Positives = 26/58 (44%), Gaps = 13/58 (22%)
Query: 119 GLLRCLGCRGFLSEPVTVPCGHSYCRRCLRREL-------------RARCRLCRDRLP 163
G C C L EPVT+PCGH++C CL ARC LC++ P
Sbjct: 5 GPFSCPICLEPLREPVTLPCGHNFCLACLGALWPHRGASGAGGPGGAARCPLCQEPFP 62
>gi|115430235 ubiquitin-like with PHD and ring finger domains 1
isoform 1 [Homo sapiens]
Length = 793
Score = 49.3 bits (116), Expect = 1e-05
Identities = 48/204 (23%), Positives = 75/204 (36%), Gaps = 20/204 (9%)
Query: 344 LPCTKNRPFDFHSVMEESQSLNEPSPKQSEEIPE---VTSEPVKGSLNRAQSAQSINSTE 400
L T P + + + E S ++ EE E + KG R + +
Sbjct: 601 LGLTMQYPEGYLEALANREREKENSKREEEEQQEGGFASPRTGKGKWKRKSAGGGPSRAG 660
Query: 401 MPAREDCLKRVSSEPVLSVQEKGVLLKRKLSLLEQDVIVNEDGRNKLKKQGETPNEVCMF 460
P R K+ EP L ++ SL+ +D + L + P F
Sbjct: 661 SPRRTS--KKTKVEPYS-------LTAQQSSLIREDKSNAKLWNEVLASLKDRPASGSPF 711
Query: 461 SLAYGDIPEELIDVSDFECSLCMRLFFEPVTTPCGHSFCKNCLERCLDHAPY-CPLCKES 519
L + E F+C C L F P+TT C H+ CK+CL+R + CP C+
Sbjct: 712 QLFLSKVEET------FQCICCQELVFRPITTVCQHNVCKDCLDRSFRAQVFSCPACRYD 765
Query: 520 L-KEYLADRRYCVTQLLEELIVKY 542
L + Y + +L +L Y
Sbjct: 766 LGRSYAMQVNQPLQTVLNQLFPGY 789
Score = 37.4 bits (85), Expect = 0.053
Identities = 15/41 (36%), Positives = 23/41 (56%), Gaps = 3/41 (7%)
Query: 122 RCLGCRGFLSEPVTVPCGHSYCRRCLRRELRAR---CRLCR 159
+C+ C+ + P+T C H+ C+ CL R RA+ C CR
Sbjct: 723 QCICCQELVFRPITTVCQHNVCKDCLDRSFRAQVFSCPACR 763
>gi|115430233 ubiquitin-like with PHD and ring finger domains 1
isoform 2 [Homo sapiens]
Length = 806
Score = 49.3 bits (116), Expect = 1e-05
Identities = 48/204 (23%), Positives = 75/204 (36%), Gaps = 20/204 (9%)
Query: 344 LPCTKNRPFDFHSVMEESQSLNEPSPKQSEEIPE---VTSEPVKGSLNRAQSAQSINSTE 400
L T P + + + E S ++ EE E + KG R + +
Sbjct: 614 LGLTMQYPEGYLEALANREREKENSKREEEEQQEGGFASPRTGKGKWKRKSAGGGPSRAG 673
Query: 401 MPAREDCLKRVSSEPVLSVQEKGVLLKRKLSLLEQDVIVNEDGRNKLKKQGETPNEVCMF 460
P R K+ EP L ++ SL+ +D + L + P F
Sbjct: 674 SPRRTS--KKTKVEPYS-------LTAQQSSLIREDKSNAKLWNEVLASLKDRPASGSPF 724
Query: 461 SLAYGDIPEELIDVSDFECSLCMRLFFEPVTTPCGHSFCKNCLERCLDHAPY-CPLCKES 519
L + E F+C C L F P+TT C H+ CK+CL+R + CP C+
Sbjct: 725 QLFLSKVEET------FQCICCQELVFRPITTVCQHNVCKDCLDRSFRAQVFSCPACRYD 778
Query: 520 L-KEYLADRRYCVTQLLEELIVKY 542
L + Y + +L +L Y
Sbjct: 779 LGRSYAMQVNQPLQTVLNQLFPGY 802
Score = 37.4 bits (85), Expect = 0.053
Identities = 15/41 (36%), Positives = 23/41 (56%), Gaps = 3/41 (7%)
Query: 122 RCLGCRGFLSEPVTVPCGHSYCRRCLRRELRAR---CRLCR 159
+C+ C+ + P+T C H+ C+ CL R RA+ C CR
Sbjct: 736 QCICCQELVFRPITTVCQHNVCKDCLDRSFRAQVFSCPACR 776
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.321 0.137 0.422
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 32,132,047
Number of Sequences: 37866
Number of extensions: 1595029
Number of successful extensions: 6957
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 232
Number of HSP's successfully gapped in prelim test: 136
Number of HSP's that attempted gapping in prelim test: 6318
Number of HSP's gapped (non-prelim): 754
length of query: 773
length of database: 18,247,518
effective HSP length: 110
effective length of query: 663
effective length of database: 14,082,258
effective search space: 9336537054
effective search space used: 9336537054
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.