BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|85067501 arachidonate 15-lipoxygenase, second type isoform d [Homo sapiens] (676 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|85067501 arachidonate 15-lipoxygenase, second type isoform d ... 1392 0.0 gi|85067499 arachidonate 15-lipoxygenase, second type isoform a ... 1320 0.0 gi|85067503 arachidonate 15-lipoxygenase, second type isoform b ... 1210 0.0 gi|182765464 arachidonate lipoxygenase 3 [Homo sapiens] 728 0.0 gi|4502053 arachidonate 12-lipoxygenase, 12R type [Homo sapiens] 694 0.0 gi|4502057 arachidonate 5-lipoxygenase [Homo sapiens] 557 e-158 gi|154426292 arachidonate 12-lipoxygenase [Homo sapiens] 467 e-131 gi|40316937 arachidonate 15-lipoxygenase [Homo sapiens] 458 e-129 gi|239050813 lipoxygenase homology domains 1 isoform 1 [Homo sap... 42 0.002 gi|118402590 myosin XV [Homo sapiens] 33 0.66 gi|69885149 Fc receptor-like and mucin-like 1 [Homo sapiens] 33 0.66 gi|239756667 PREDICTED: hypothetical protein [Homo sapiens] 33 1.1 gi|239751165 PREDICTED: hypothetical protein XP_002347739 [Homo ... 33 1.1 gi|239745650 PREDICTED: hypothetical protein XP_002344167 [Homo ... 33 1.1 gi|195972805 myocyte enhancer factor 2A isoform 4 [Homo sapiens] 32 1.5 gi|195972803 myocyte enhancer factor 2A isoform 3 [Homo sapiens] 32 1.5 gi|195972801 myocyte enhancer factor 2A isoform 2 [Homo sapiens] 32 1.5 gi|224458288 lipoxygenase homology domains 1 isoform 2 [Homo sap... 31 3.3 gi|239755589 PREDICTED: hypothetical protein [Homo sapiens] 31 4.3 gi|155969714 nuclear protein, ataxia-telangiectasia locus [Homo... 30 5.6 gi|117168250 phospholipase C, epsilon 1 [Homo sapiens] 30 7.3 gi|4557701 keratin 17 [Homo sapiens] 30 7.3 gi|5031653 breast carcinoma amplified sequence 2 [Homo sapiens] 30 7.3 gi|205360962 polycystin 1 isoform 2 precursor [Homo sapiens] 30 9.5 gi|205360954 polycystin 1 isoform 1 precursor [Homo sapiens] 30 9.5 gi|194248077 Kruppel-like factor 4 (gut) [Homo sapiens] 30 9.5 >gi|85067501 arachidonate 15-lipoxygenase, second type isoform d [Homo sapiens] Length = 676 Score = 1392 bits (3603), Expect = 0.0 Identities = 676/676 (100%), Positives = 676/676 (100%) Query: 1 MAEFRVRVSTGEAFGAGTWDKVSVSIVGTRGESPPLPLDNLGKEFTAGAEEDFQVTLPED 60 MAEFRVRVSTGEAFGAGTWDKVSVSIVGTRGESPPLPLDNLGKEFTAGAEEDFQVTLPED Sbjct: 1 MAEFRVRVSTGEAFGAGTWDKVSVSIVGTRGESPPLPLDNLGKEFTAGAEEDFQVTLPED 60 Query: 61 VGRVLLLRVHKAPPVLPLLGPLAPDAWFCRWFQLTPPRGGHLLFPCYQWLEGAGTLVLQE 120 VGRVLLLRVHKAPPVLPLLGPLAPDAWFCRWFQLTPPRGGHLLFPCYQWLEGAGTLVLQE Sbjct: 61 VGRVLLLRVHKAPPVLPLLGPLAPDAWFCRWFQLTPPRGGHLLFPCYQWLEGAGTLVLQE 120 Query: 121 GTAKVSWADHHPVLQQQRQEELQARQEMYQWKAYNPGWPHCLDEKTVEDLELNIKYSTAK 180 GTAKVSWADHHPVLQQQRQEELQARQEMYQWKAYNPGWPHCLDEKTVEDLELNIKYSTAK Sbjct: 121 GTAKVSWADHHPVLQQQRQEELQARQEMYQWKAYNPGWPHCLDEKTVEDLELNIKYSTAK 180 Query: 181 NANFYLQAGSAFAEMKIKGLLDRKGLWRSLNEMKRIFNFRRTPAAEHAFEHWQEDAFFAS 240 NANFYLQAGSAFAEMKIKGLLDRKGLWRSLNEMKRIFNFRRTPAAEHAFEHWQEDAFFAS Sbjct: 181 NANFYLQAGSAFAEMKIKGLLDRKGLWRSLNEMKRIFNFRRTPAAEHAFEHWQEDAFFAS 240 Query: 241 QFLNGLNPVLIRRCHYLPKNFPVTDAMVASVLGPGTSLQAELEKGSLFLVDHGILSGIQT 300 QFLNGLNPVLIRRCHYLPKNFPVTDAMVASVLGPGTSLQAELEKGSLFLVDHGILSGIQT Sbjct: 241 QFLNGLNPVLIRRCHYLPKNFPVTDAMVASVLGPGTSLQAELEKGSLFLVDHGILSGIQT 300 Query: 301 NVINGKPQFSAAPMTLLYQSPGCGPLLPLAIQLSQTPGPNSPIFLPTDDKWDWLLAKTWV 360 NVINGKPQFSAAPMTLLYQSPGCGPLLPLAIQLSQTPGPNSPIFLPTDDKWDWLLAKTWV Sbjct: 301 NVINGKPQFSAAPMTLLYQSPGCGPLLPLAIQLSQTPGPNSPIFLPTDDKWDWLLAKTWV 360 Query: 361 RNAEFSFHEALTHLLHSHLLPEVFTLATLRQLPHCHPLFKLLIPHTRYTLHINTLARELL 420 RNAEFSFHEALTHLLHSHLLPEVFTLATLRQLPHCHPLFKLLIPHTRYTLHINTLARELL Sbjct: 361 RNAEFSFHEALTHLLHSHLLPEVFTLATLRQLPHCHPLFKLLIPHTRYTLHINTLARELL 420 Query: 421 IVPGQVVDRSTGIGIEGFSELIQRNMKQLNYSLLCLPEDIRTRGVEDIPGYYYRDDGMQI 480 IVPGQVVDRSTGIGIEGFSELIQRNMKQLNYSLLCLPEDIRTRGVEDIPGYYYRDDGMQI Sbjct: 421 IVPGQVVDRSTGIGIEGFSELIQRNMKQLNYSLLCLPEDIRTRGVEDIPGYYYRDDGMQI 480 Query: 481 WGAVERFVSEIIGIYYPSDESVQDDRELQAWVREIFSKGFLNQESSGIPSSLETREALVQ 540 WGAVERFVSEIIGIYYPSDESVQDDRELQAWVREIFSKGFLNQESSGIPSSLETREALVQ Sbjct: 481 WGAVERFVSEIIGIYYPSDESVQDDRELQAWVREIFSKGFLNQESSGIPSSLETREALVQ 540 Query: 541 YVTMVIFTCSAKHAAVSAGQFDSCAWMPNLPPSMQLPPPTSKGLATCEGFIATLPPVNAT 600 YVTMVIFTCSAKHAAVSAGQFDSCAWMPNLPPSMQLPPPTSKGLATCEGFIATLPPVNAT Sbjct: 541 YVTMVIFTCSAKHAAVSAGQFDSCAWMPNLPPSMQLPPPTSKGLATCEGFIATLPPVNAT 600 Query: 601 CDVILALWLLSKEPGDQRPLGTYPDEHFTEEAPRRSIATFQSRLAQISRGIQERNQGLVL 660 CDVILALWLLSKEPGDQRPLGTYPDEHFTEEAPRRSIATFQSRLAQISRGIQERNQGLVL Sbjct: 601 CDVILALWLLSKEPGDQRPLGTYPDEHFTEEAPRRSIATFQSRLAQISRGIQERNQGLVL 660 Query: 661 PYTYLDPPLIENSVSI 676 PYTYLDPPLIENSVSI Sbjct: 661 PYTYLDPPLIENSVSI 676 >gi|85067499 arachidonate 15-lipoxygenase, second type isoform a [Homo sapiens] Length = 647 Score = 1320 bits (3416), Expect = 0.0 Identities = 647/676 (95%), Positives = 647/676 (95%), Gaps = 29/676 (4%) Query: 1 MAEFRVRVSTGEAFGAGTWDKVSVSIVGTRGESPPLPLDNLGKEFTAGAEEDFQVTLPED 60 MAEFRVRVSTGEAFGAGTWDKVSVSIVGTRGESPPLPLDNLGKEFTAGAEEDFQVTLPED Sbjct: 1 MAEFRVRVSTGEAFGAGTWDKVSVSIVGTRGESPPLPLDNLGKEFTAGAEEDFQVTLPED 60 Query: 61 VGRVLLLRVHKAPPVLPLLGPLAPDAWFCRWFQLTPPRGGHLLFPCYQWLEGAGTLVLQE 120 VGRVLLLRVHKAPPVLPLLGPLAPDAWFCRWFQLTPPRGGHLLFPCYQWLEGAGTLVLQE Sbjct: 61 VGRVLLLRVHKAPPVLPLLGPLAPDAWFCRWFQLTPPRGGHLLFPCYQWLEGAGTLVLQE 120 Query: 121 GTAKVSWADHHPVLQQQRQEELQARQEMYQWKAYNPGWPHCLDEKTVEDLELNIKYSTAK 180 GTAKVSWADHHPVLQQQRQEELQARQEMYQWKAYNPGWPHCLDEKTVEDLELNIKYSTAK Sbjct: 121 GTAKVSWADHHPVLQQQRQEELQARQEMYQWKAYNPGWPHCLDEKTVEDLELNIKYSTAK 180 Query: 181 NANFYLQAGSAFAEMKIKGLLDRKGLWRSLNEMKRIFNFRRTPAAEHAFEHWQEDAFFAS 240 NANFYLQAGSAFAEMKIKGLLDRKGLWRSLNEMKRIFNFRRTPAAEHAFEHWQEDAFFAS Sbjct: 181 NANFYLQAGSAFAEMKIKGLLDRKGLWRSLNEMKRIFNFRRTPAAEHAFEHWQEDAFFAS 240 Query: 241 QFLNGLNPVLIRRCHYLPKNFPVTDAMVASVLGPGTSLQAELEKGSLFLVDHGILSGIQT 300 QFLNGLNPVLIRRCHYLPKNFPVTDAMVASVLGPGTSLQAELEKGSLFLVDHGILSGIQT Sbjct: 241 QFLNGLNPVLIRRCHYLPKNFPVTDAMVASVLGPGTSLQAELEKGSLFLVDHGILSGIQT 300 Query: 301 NVINGKPQFSAAPMTLLYQSPGCGPLLPLAIQLSQTPGPNSPIFLPTDDKWDWLLAKTWV 360 NVINGKPQFSAAPMTLLYQSPGCGPLLPLAIQLSQTPGPNSPIFLPTDDKWDWLLAKTWV Sbjct: 301 NVINGKPQFSAAPMTLLYQSPGCGPLLPLAIQLSQTPGPNSPIFLPTDDKWDWLLAKTWV 360 Query: 361 RNAEFSFHEALTHLLHSHLLPEVFTLATLRQLPHCHPLFKLLIPHTRYTLHINTLARELL 420 RNAEFSFHEALTHLLHSHLLPEVFTLATLRQLPHCHPLFK Sbjct: 361 RNAEFSFHEALTHLLHSHLLPEVFTLATLRQLPHCHPLFK-------------------- 400 Query: 421 IVPGQVVDRSTGIGIEGFSELIQRNMKQLNYSLLCLPEDIRTRGVEDIPGYYYRDDGMQI 480 STGIGIEGFSELIQRNMKQLNYSLLCLPEDIRTRGVEDIPGYYYRDDGMQI Sbjct: 401 ---------STGIGIEGFSELIQRNMKQLNYSLLCLPEDIRTRGVEDIPGYYYRDDGMQI 451 Query: 481 WGAVERFVSEIIGIYYPSDESVQDDRELQAWVREIFSKGFLNQESSGIPSSLETREALVQ 540 WGAVERFVSEIIGIYYPSDESVQDDRELQAWVREIFSKGFLNQESSGIPSSLETREALVQ Sbjct: 452 WGAVERFVSEIIGIYYPSDESVQDDRELQAWVREIFSKGFLNQESSGIPSSLETREALVQ 511 Query: 541 YVTMVIFTCSAKHAAVSAGQFDSCAWMPNLPPSMQLPPPTSKGLATCEGFIATLPPVNAT 600 YVTMVIFTCSAKHAAVSAGQFDSCAWMPNLPPSMQLPPPTSKGLATCEGFIATLPPVNAT Sbjct: 512 YVTMVIFTCSAKHAAVSAGQFDSCAWMPNLPPSMQLPPPTSKGLATCEGFIATLPPVNAT 571 Query: 601 CDVILALWLLSKEPGDQRPLGTYPDEHFTEEAPRRSIATFQSRLAQISRGIQERNQGLVL 660 CDVILALWLLSKEPGDQRPLGTYPDEHFTEEAPRRSIATFQSRLAQISRGIQERNQGLVL Sbjct: 572 CDVILALWLLSKEPGDQRPLGTYPDEHFTEEAPRRSIATFQSRLAQISRGIQERNQGLVL 631 Query: 661 PYTYLDPPLIENSVSI 676 PYTYLDPPLIENSVSI Sbjct: 632 PYTYLDPPLIENSVSI 647 >gi|85067503 arachidonate 15-lipoxygenase, second type isoform b [Homo sapiens] Length = 602 Score = 1210 bits (3131), Expect = 0.0 Identities = 602/676 (89%), Positives = 602/676 (89%), Gaps = 74/676 (10%) Query: 1 MAEFRVRVSTGEAFGAGTWDKVSVSIVGTRGESPPLPLDNLGKEFTAGAEEDFQVTLPED 60 MAEFRVRVSTGEAFGAGTWDKVSVSIVGTRGESPPLPLDNLGKEFTAGAEEDFQVTLPED Sbjct: 1 MAEFRVRVSTGEAFGAGTWDKVSVSIVGTRGESPPLPLDNLGKEFTAGAEEDFQVTLPED 60 Query: 61 VGRVLLLRVHKAPPVLPLLGPLAPDAWFCRWFQLTPPRGGHLLFPCYQWLEGAGTLVLQE 120 VGRVLLLRVHKAPPVLPLLGPLAPDAWFCRWFQLTPPRGGHLLFPCYQWLEGAGTLVLQE Sbjct: 61 VGRVLLLRVHKAPPVLPLLGPLAPDAWFCRWFQLTPPRGGHLLFPCYQWLEGAGTLVLQE 120 Query: 121 GTAKVSWADHHPVLQQQRQEELQARQEMYQWKAYNPGWPHCLDEKTVEDLELNIKYSTAK 180 GTAKVSWADHHPVLQQQRQEELQARQEMYQWKAYNPGWPHCLDEKTVEDLELNIKYSTAK Sbjct: 121 GTAKVSWADHHPVLQQQRQEELQARQEMYQWKAYNPGWPHCLDEKTVEDLELNIKYSTAK 180 Query: 181 NANFYLQAGSAFAEMKIKGLLDRKGLWRSLNEMKRIFNFRRTPAAEHAFEHWQEDAFFAS 240 NANFYLQAGSAFAEMKIKGLLDRKGLWRSLNEMKRIFNFRRTPAAEHAFEHWQEDAFFAS Sbjct: 181 NANFYLQAGSAFAEMKIKGLLDRKGLWRSLNEMKRIFNFRRTPAAEHAFEHWQEDAFFAS 240 Query: 241 QFLNGLNPVLIRRCHYLPKNFPVTDAMVASVLGPGTSLQAELEKGSLFLVDHGILSGIQT 300 QFLNGLNPVLIRRCHYLPKNFPVTDAMVASVLGPGTSLQAELEKGSLFLVDHGILSGIQT Sbjct: 241 QFLNGLNPVLIRRCHYLPKNFPVTDAMVASVLGPGTSLQAELEKGSLFLVDHGILSGIQT 300 Query: 301 NVINGKPQFSAAPMTLLYQSPGCGPLLPLAIQLSQTPGPNSPIFLPTDDKWDWLLAKTWV 360 NVINGKPQFSAAPMTLLYQSPGCGPLLPLAIQLSQTPGPNSPIFLPTDDKWDWLLAKTWV Sbjct: 301 NVINGKPQFSAAPMTLLYQSPGCGPLLPLAIQLSQTPGPNSPIFLPTDDKWDWLLAKTWV 360 Query: 361 RNAEFSFHEALTHLLHSHLLPEVFTLATLRQLPHCHPLFKLLIPHTRYTLHINTLARELL 420 RNAEFSFHEALTHLLHSHLLPEVFTLATLRQLPHCHPLFK Sbjct: 361 RNAEFSFHEALTHLLHSHLLPEVFTLATLRQLPHCHPLFK-------------------- 400 Query: 421 IVPGQVVDRSTGIGIEGFSELIQRNMKQLNYSLLCLPEDIRTRGVEDIPGYYYRDDGMQI 480 STGIGIEGFSELIQRNMKQLNYSLLCLPEDIRTRGVEDIPGYYYRDDGMQI Sbjct: 401 ---------STGIGIEGFSELIQRNMKQLNYSLLCLPEDIRTRGVEDIPGYYYRDDGMQI 451 Query: 481 WGAVERFVSEIIGIYYPSDESVQDDRELQAWVREIFSKGFLNQESSGIPSSLETREALVQ 540 W GIPSSLETREALVQ Sbjct: 452 W---------------------------------------------GIPSSLETREALVQ 466 Query: 541 YVTMVIFTCSAKHAAVSAGQFDSCAWMPNLPPSMQLPPPTSKGLATCEGFIATLPPVNAT 600 YVTMVIFTCSAKHAAVSAGQFDSCAWMPNLPPSMQLPPPTSKGLATCEGFIATLPPVNAT Sbjct: 467 YVTMVIFTCSAKHAAVSAGQFDSCAWMPNLPPSMQLPPPTSKGLATCEGFIATLPPVNAT 526 Query: 601 CDVILALWLLSKEPGDQRPLGTYPDEHFTEEAPRRSIATFQSRLAQISRGIQERNQGLVL 660 CDVILALWLLSKEPGDQRPLGTYPDEHFTEEAPRRSIATFQSRLAQISRGIQERNQGLVL Sbjct: 527 CDVILALWLLSKEPGDQRPLGTYPDEHFTEEAPRRSIATFQSRLAQISRGIQERNQGLVL 586 Query: 661 PYTYLDPPLIENSVSI 676 PYTYLDPPLIENSVSI Sbjct: 587 PYTYLDPPLIENSVSI 602 >gi|182765464 arachidonate lipoxygenase 3 [Homo sapiens] Length = 711 Score = 728 bits (1878), Expect = 0.0 Identities = 369/717 (51%), Positives = 476/717 (66%), Gaps = 47/717 (6%) Query: 1 MAEFRVRVSTGEAFGAGTWDKVSVSIVGTRGESPPLPLDNLGKEFTAGAEEDFQVTLPED 60 MA +R+ V+TG AGT D +SV++VGT GESP LD +G++F G+ + ++V + Sbjct: 1 MAVYRLCVTTGPYLRAGTLDNISVTLVGTCGESPKQRLDRMGRDFAPGSVQKYKVRCTAE 60 Query: 61 VGRVLLLRVHKAPPVLPLLGPLAPDAWFCRWFQLTPPRGGHLLFPCYQWLEGAGTLVLQE 120 +G +LLLRVHK D+W+C +T P G FPCYQW+EG T+ L+ Sbjct: 61 LGELLLLRVHKERYAF-----FRKDSWYCSRICVTEPDGSVSHFPCYQWIEGYCTVELRP 115 Query: 121 GTAKVSWADHHPVLQQQRQEELQARQEMYQWKAYNPGWPHCLDEKTVEDLEL-------- 172 GTA+ D P+L R EL+ARQE Y+WK Y PG+P +D + +++E Sbjct: 116 GTARTICQDSLPLLLDHRTRELRARQECYRWKIYAPGFPCMVDVNSFQEMESDKKFALTK 175 Query: 173 ---------------------------------NIKYSTAKNANFYLQAGSAFAEMKIKG 199 N++YS K + A A MK++G Sbjct: 176 TTTCVDQGDSSGNRYLPGFPMKIDIPSLMYMEPNVRYSATKTISLLFNAIPASLGMKLRG 235 Query: 200 LLDRKGLWRSLNEMKRIFNFRRTPAAEHAFEHWQEDAFFASQFLNGLNPVLIRRCHYLPK 259 LLDRKG W+ L++M+ IF +T ++ EHW ED FF Q+LNG+NPV++ LP Sbjct: 236 LLDRKGSWKKLDDMQNIFWCHKTFTTKYVTEHWCEDHFFGYQYLNGVNPVMLHCISSLPS 295 Query: 260 NFPVTDAMVASVLGPGTSLQAELEKGSLFLVDHGILSGIQTNVINGKPQFSAAPMTLLYQ 319 PVT+ MVA +LG T LQ ELE+G++FL D+ IL+ T+ +NG+ Q+ AAP+ LL+ Sbjct: 296 KLPVTNDMVAPLLGQDTCLQTELERGNIFLADYWILAEAPTHCLNGRQQYVAAPLCLLWL 355 Query: 320 SPGCGPLLPLAIQLSQTPGPNSPIFLPTDDKWDWLLAKTWVRNAEFSFHEALTHLLHSHL 379 SP G L+PLAIQLSQTPGP+SPIFLPTD +WDWLLAKTWVRN+EF HE TH L +HL Sbjct: 356 SPQ-GALVPLAIQLSQTPGPDSPIFLPTDSEWDWLLAKTWVRNSEFLVHENNTHFLCTHL 414 Query: 380 LPEVFTLATLRQLPHCHPLFKLLIPHTRYTLHINTLARELLIVPGQVVDRSTGIGIEGFS 439 L E F +ATLRQLP CHP++KLL+PHTRYTL +NT+AR L+ P +VD+ T IG +G Sbjct: 415 LCEAFAMATLRQLPLCHPIYKLLLPHTRYTLQVNTIARATLLNPEGLVDQVTSIGRQGLI 474 Query: 440 ELIQRNMKQLNYSLLCLPEDIRTRGVEDIPGYYYRDDGMQIWGAVERFVSEIIGIYYPSD 499 L+ + Y+ CLP+ +R RGV IP Y+YRDDG++IW A+E FVSEI+G YYPSD Sbjct: 475 YLMSTGLAHFTYTNFCLPDSLRARGVLAIPNYHYRDDGLKIWAAIESFVSEIVGYYYPSD 534 Query: 500 ESVQDDRELQAWVREIFSKGFLNQESSGIPSSLETREALVQYVTMVIFTCSAKHAAVSAG 559 SVQ D ELQAW EIF++ FL +ESSG PS L T +V+++T +IF CSA+HAAV++G Sbjct: 535 ASVQQDSELQAWTGEIFAQAFLGRESSGFPSRLCTPGEMVKFLTAIIFNCSAQHAAVNSG 594 Query: 560 QFDSCAWMPNLPPSMQLPPPTSKGLATCEGFIATLPPVNATCDVILALWLLSKEPGDQRP 619 Q D AWMPN P SM+ PPP +KG T + ++ TLP VN +C+ +L WL+S+EP DQRP Sbjct: 595 QHDFGAWMPNAPSSMRQPPPQTKGTTTLKTYLDTLPEVNISCNNLLLFWLVSQEPKDQRP 654 Query: 620 LGTYPDEHFTEEAPRRSIATFQSRLAQISRGIQERNQGLVLPYTYLDPPLIENSVSI 676 LGTYPDEHFTEEAPRRSIA FQSRLAQISR IQERNQGL LPYTYLDPPLIENSVSI Sbjct: 655 LGTYPDEHFTEEAPRRSIAAFQSRLAQISRDIQERNQGLALPYTYLDPPLIENSVSI 711 >gi|4502053 arachidonate 12-lipoxygenase, 12R type [Homo sapiens] Length = 701 Score = 694 bits (1792), Expect = 0.0 Identities = 342/707 (48%), Positives = 468/707 (66%), Gaps = 37/707 (5%) Query: 1 MAEFRVRVSTGEAFGAGTWDKVSVSIVGTRGESPPLPLDNLGKEFTAGAEEDFQVTLPED 60 MA ++VRV+TG +GT D +S++IVGT+GES L++ G++F GA + V P+D Sbjct: 1 MATYKVRVATGTDLLSGTRDSISLTIVGTQGESHKQLLNHFGRDFATGAVGQYTVQCPQD 60 Query: 61 VGRVLLLRVHKAPPVLPLLGPLAPDAWFCRWFQLTPPRGGHLLFPCYQWLEGAGTLVLQE 120 +G ++++R+HK D W+C + Q+ P G FP YQW++G TL L+E Sbjct: 61 LGELIIIRLHKERYAF-----FPKDPWYCNYVQICAPNGRIYHFPAYQWMDGYETLALRE 115 Query: 121 GTAKVSWADHHPVLQQQRQEELQARQEMYQWKA--------------------------- 153 T K + D PVL + R+EE++A+Q+ Y W+ Sbjct: 116 ATGKTTADDSLPVLLEHRKEEIRAKQDFYHWRVFLPGLPSYVHIPSYRPPVRRHRNPNRP 175 Query: 154 ----YNPGWPHCLDEKTVEDLELNIKYSTAKNANFYLQAGSAFAEMKIKGLLDRKGLWRS 209 Y PG+P ++ K + L LN++YS K A+F+++ G K++GLLD K W+ Sbjct: 176 EWNGYIPGFPILINFKATKFLNLNLRYSFLKTASFFVRLGPMALAFKVRGLLDCKHSWKR 235 Query: 210 LNEMKRIFNFRRTPAAEHAFEHWQEDAFFASQFLNGLNPVLIRRCHYLPKNFPVTDAMVA 269 L ++++IF +++ +E+ EHW ED FF Q+LNG+NP LIRRC +P FPVTD MVA Sbjct: 236 LKDIRKIFPGKKSVVSEYVAEHWAEDTFFGYQYLNGVNPGLIRRCTRIPDKFPVTDDMVA 295 Query: 270 SVLGPGTSLQAELEKGSLFLVDHGILSGIQTNVINGKPQFSAAPMTLLYQSPGCGPLLPL 329 LG GT LQAELEKG+++L D+ I+ GI T ++G+ Q AP+ LL+ P G ++P+ Sbjct: 296 PFLGEGTCLQAELEKGNIYLADYRIMEGIPTVELSGRKQHHCAPLCLLHFGPE-GKMMPI 354 Query: 330 AIQLSQTPGPNSPIFLPTDDKWDWLLAKTWVRNAEFSFHEALTHLLHSHLLPEVFTLATL 389 AIQLSQTPGP+ PIFLP+D +WDWLLAKTWVR AEF HEA+ HLL +HL+ E F LA L Sbjct: 355 AIQLSQTPGPDCPIFLPSDSEWDWLLAKTWVRYAEFYSHEAIAHLLETHLIAEAFCLALL 414 Query: 390 RQLPHCHPLFKLLIPHTRYTLHINTLARELLIVPGQVVDRSTGIGIEGFSELIQRNMKQL 449 R LP CHPL+KLLIPHTRYT+ IN++ R +L+ G + + +G+EGF+ ++ R + +L Sbjct: 415 RNLPMCHPLYKLLIPHTRYTVQINSIGRAVLLNEGGLSAKGMSLGVEGFAGVMVRALSEL 474 Query: 450 NYSLLCLPEDIRTRGVEDIPGYYYRDDGMQIWGAVERFVSEIIGIYYPSDESVQDDRELQ 509 Y L LP D RGV+D+PGYYYRDD + +W A+E++V+EII YYPSD +V+ D ELQ Sbjct: 475 TYDSLYLPNDFVERGVQDLPGYYYRDDSLAVWNALEKYVTEIITYYYPSDAAVEGDPELQ 534 Query: 510 AWVREIFSKGFLNQESSGIPSSLETREALVQYVTMVIFTCSAKHAAVSAGQFDSCAWMPN 569 +WV+EIF + L +ESSG P L T L++YVT+VI+TCSAKHAAV+ GQ + AWMPN Sbjct: 535 SWVQEIFKECLLGRESSGFPRCLRTVPELIRYVTIVIYTCSAKHAAVNTGQMEFTAWMPN 594 Query: 570 LPPSMQLPPPTSKGLATCEGFIATLPPVNATCDVILALWLLSKEPGDQRPLGTYPDEHFT 629 P SM+ PP +KGL T E F+ TLP V TC +L LW LS+EP D+RPLG +PD HF Sbjct: 595 FPASMRNPPIQTKGLTTLETFMDTLPDVKTTCITLLVLWTLSREPDDRRPLGHFPDIHFV 654 Query: 630 EEAPRRSIATFQSRLAQISRGIQERNQGLVLPYTYLDPPLIENSVSI 676 EEAPRRSI F+ RL QIS I++RN+ L +PY YLDP LIENS+SI Sbjct: 655 EEAPRRSIEAFRQRLNQISHDIRQRNKCLPIPYYYLDPVLIENSISI 701 >gi|4502057 arachidonate 5-lipoxygenase [Homo sapiens] Length = 674 Score = 557 bits (1435), Expect = e-158 Identities = 288/682 (42%), Positives = 426/682 (62%), Gaps = 14/682 (2%) Query: 1 MAEFRVRVSTGEAFGAGTWDKVSVSIVGTRGESPPLPLDN-LGKEFTAGAEEDFQVTLPE 59 M + V V+TG + AGT D + +S+VG+ G S LD +F GA + + VT+ E Sbjct: 1 MPSYTVTVATGSQWFAGTDDYIYLSLVGSAGCSEKHLLDKPFYNDFERGAVDSYDVTVDE 60 Query: 60 DVGRVLLLRVHKAPPVLPLLGPLAPDAWFCRWFQLTPPRGGHLLFPCYQWLEGAGTLVLQ 119 ++G + L+R+ K L D W+ ++ L P G ++ FPCY+W+ G +VL+ Sbjct: 61 ELGEIQLVRIEKRKYWLN-------DDWYLKYITLKTPHGDYIEFPCYRWITGDVEVVLR 113 Query: 120 EGTAKVSWADHHPVLQQQRQEELQARQEMYQWKAYNPGWPHCLDEKTVEDLELNIKYSTA 179 +G AK++ D +L+Q R++EL+ RQ+ Y+W +NPG+P +D K +DL +I++ + Sbjct: 114 DGRAKLARDDQIHILKQHRRKELETRQKQYRWMEWNPGFPLSIDAKCHKDLPRDIQFDSE 173 Query: 180 KNANFYLQAGSAFAEMKIKGLLDR-KGLWRSLNEMKRIFNFRRTPAAEHAFEHWQEDAFF 238 K +F L A + I + + W + ++IF +E HWQED F Sbjct: 174 KGVDFVLNYSKAMENLFINRFMHMFQSSWNDFADFEKIFVKISNTISERVMNHWQEDLMF 233 Query: 239 ASQFLNGLNPVLIRRCHYLPKNFPVTDAMVASVLGPGTSLQAELEKGSLFLVDHGILSGI 298 QFLNG NPVLIRRC LP+ PVT MV L SL+ E+++G++F+VD +L GI Sbjct: 234 GYQFLNGCNPVLIRRCTELPEKLPVTTEMVECSLERQLSLEQEVQQGNIFIVDFELLDGI 293 Query: 299 QTNVINGKP-QFSAAPMTLLYQSPGCGPLLPLAIQLSQTPGPNSPIFLPTDDKWDWLLAK 357 N + QF AAP+ LLY++ ++P+AIQL+Q PG +PIFLP+D K+DWLLAK Sbjct: 294 DANKTDPCTLQFLAAPICLLYKNLA-NKIVPIAIQLNQIPGDENPIFLPSDAKYDWLLAK 352 Query: 358 TWVRNAEFSFHEALTHLLHSHLLPEVFTLATLRQLPHCHPLFKLLIPHTRYTLHINTLAR 417 WVR+++F H+ +THLL +HL+ EVF +A RQLP HP+FKLL+ H R+T+ INT AR Sbjct: 353 IWVRSSDFHVHQTITHLLRTHLVSEVFGIAMYRQLPAVHPIFKLLVAHVRFTIAINTKAR 412 Query: 418 ELLIVPGQVVDRSTGIGIEGFSELIQRNMKQLNYSLLCLPEDIRTRGVE---DIPGYYYR 474 E LI + D++ G G +++QR MK L Y+ LC PE I+ RG+E DIP Y+YR Sbjct: 413 EQLICECGLFDKANATGGGGHVQMVQRAMKDLTYASLCFPEAIKARGMESKEDIPYYFYR 472 Query: 475 DDGMQIWGAVERFVSEIIGIYYPSDESVQDDRELQAWVREIFSKGFLNQESSGIPSSLET 534 DDG+ +W A+ F +E++ IYY D+ V++D ELQ +V +++ G ++SSG P S+++ Sbjct: 473 DDGLLVWEAIRTFTAEVVDIYYEGDQVVEEDPELQDFVNDVYVYGMRGRKSSGFPKSVKS 532 Query: 535 REALVQYVTMVIFTCSAKHAAVSAGQFDSCAWMPNLPPSMQLPPPTSKGLATCEGFIATL 594 RE L +Y+T+VIFT SA+HAAV+ GQ+D C+W+PN PP+M+ PPPT+KG+ T E + TL Sbjct: 533 REQLSEYLTVVIFTASAQHAAVNFGQYDWCSWIPNAPPTMRAPPPTAKGVVTIEQIVDTL 592 Query: 595 PPVNATCDVILALWLLSKEPGDQRPLGTYPDEHFTEEAPRRSIATFQSRLAQISRGIQER 654 P +C + A+W LS+ ++ LG YP+EHF E+ + ++A F+ L I I ER Sbjct: 593 PDRGRSCWHLGAVWALSQFQENELFLGMYPEEHFIEKPVKEAMARFRKNLEAIVSVIAER 652 Query: 655 NQGLVLPYTYLDPPLIENSVSI 676 N+ LPY YL P I NSV+I Sbjct: 653 NKKKQLPYYYLSPDRIPNSVAI 674 >gi|154426292 arachidonate 12-lipoxygenase [Homo sapiens] Length = 663 Score = 467 bits (1202), Expect = e-131 Identities = 255/680 (37%), Positives = 384/680 (56%), Gaps = 21/680 (3%) Query: 1 MAEFRVRVSTGEAFGAGTWDKVSVSIVGTRGESPPLPLDNLGKEFTAGAEEDFQVTLPED 60 M +R+RV+TG +G++++V + +VGTRGE+ L G EE+F + ED Sbjct: 1 MGRYRIRVATGAWLFSGSYNRVQLWLVGTRGEAEL----ELQLRPARGEEEEFDHDVAED 56 Query: 61 VGRVLLLRVHKAPPVLPLLGPLAPDAWFCRWFQLTPPRG-GHLLFPCYQWLEGAGTLVLQ 119 +G + +R+ K L DAWFC + P + FPCY+W++G L L Sbjct: 57 LGLLQFVRLRKHHW-------LVDDAWFCDRITVQGPGACAEVAFPCYRWVQGEDILSLP 109 Query: 120 EGTAKVSWADHHPVLQQQRQEELQARQEMYQWKAYNPGWPHCLDEKTVEDLELNIKYSTA 179 EGTA++ + + Q+ R++EL+ RQ++Y W + G P + +DL N+++ Sbjct: 110 EGTARLPGDNALDMFQKHREKELKDRQQIYCWATWKEGLPLTIAADRKDDLPPNMRFHEE 169 Query: 180 KNANFYLQAGSAFAEMKIKGLLDRKGLWRSLNEMKRIFNFRRTPAAEHAFEHWQEDAFFA 239 K +F + EM +K + W L + +IF +++ AE + WQ+D F+ Sbjct: 170 KRLDFEWTLKAGALEMALKRVYTLLSSWNCLEDFDQIFWGQKSALAEKVRQCWQDDELFS 229 Query: 240 SQFLNGLNPVLIRRCHYLPKNFPVTDAMVASVLGPGTSLQAELEKGSLFLVDHGILSGIQ 299 QFLNG NP+L+RR LP + M L+ EL+ GSLF D +L GI Sbjct: 230 YQFLNGANPMLLRRSTSLPSRLVLPSGMEELQ----AQLEKELQNGSLFEADFILLDGIP 285 Query: 300 TNVINGKPQFSAAPMTLLYQSPGCGPLLPLAIQLSQTPGPNSP---IFLPTDDKWDWLLA 356 NVI G+ Q+ AAP+ +L P G L P+ IQ+ Q P P+SP +FLP+D WLLA Sbjct: 286 ANVIRGEKQYLAAPLVMLKMEPN-GKLQPMVIQI-QPPNPSSPTPTLFLPSDPPLAWLLA 343 Query: 357 KTWVRNAEFSFHEALTHLLHSHLLPEVFTLATLRQLPHCHPLFKLLIPHTRYTLHINTLA 416 K+WVRN++F HE HLL++HL+ EV +AT+R LP HP+FK LIPH RYT+ INT A Sbjct: 344 KSWVRNSDFQLHEIQYHLLNTHLVAEVIAVATMRCLPGLHPIFKFLIPHIRYTMEINTRA 403 Query: 417 RELLIVPGQVVDRSTGIGIEGFSELIQRNMKQLNYSLLCLPEDIRTRGVEDIPGYYYRDD 476 R LI G + D++ G G +L++R QL Y LC P+D+ RG+ +PG Y D Sbjct: 404 RTQLISDGGIFDKAVSTGGGGHVQLLRRAAAQLTYCSLCPPDDLADRGLLGLPGALYAHD 463 Query: 477 GMQIWGAVERFVSEIIGIYYPSDESVQDDRELQAWVREIFSKGFLNQESSGIPSSLETRE 536 +++W + R+V I+ ++Y D+ V+ D ELQAW REI G + G P S +++ Sbjct: 464 ALRLWEIIARYVEGIVHLFYQRDDIVKGDPELQAWCREITEVGLCQAQDRGFPVSFQSQS 523 Query: 537 ALVQYVTMVIFTCSAKHAAVSAGQFDSCAWMPNLPPSMQLPPPTSKGLATCEGFIATLPP 596 L ++TM +FTC+A+HAA++ GQ D AW+PN P +M++PPPT+K T + +LP Sbjct: 524 QLCHFLTMCVFTCTAQHAAINQGQLDWYAWVPNAPCTMRMPPPTTKEDVTMATVMGSLPD 583 Query: 597 VNATCDVILALWLLSKEPGDQRPLGTYPDEHFTEEAPRRSIATFQSRLAQISRGIQERNQ 656 V C + W LS+ D PLG + +++F+ P+ + F++ L ++ + I RN+ Sbjct: 584 VRQACLQMAISWHLSRRQPDMVPLGHHKEKYFSGPKPKAVLNQFRTDLEKLEKEITARNE 643 Query: 657 GLVLPYTYLDPPLIENSVSI 676 L PY YL P IENSV+I Sbjct: 644 QLDWPYEYLKPSCIENSVTI 663 >gi|40316937 arachidonate 15-lipoxygenase [Homo sapiens] Length = 662 Score = 458 bits (1178), Expect = e-129 Identities = 259/686 (37%), Positives = 384/686 (55%), Gaps = 34/686 (4%) Query: 1 MAEFRVRVSTGEAFGAGTWDKVSVSIVGTRGESPPLPLDNLGKEF--TAGAEEDFQVTLP 58 M +R+RVSTG + AG+ ++V + +VG GE+ LGK G E + +V +P Sbjct: 1 MGLYRIRVSTGASLYAGSNNQVQLWLVGQHGEAA------LGKRLWPARGKETELKVEVP 54 Query: 59 EDVGRVLLLRVHKAPPVLPLLGPLAPDAWFCRWFQLTPPRGG-HLLFPCYQWLEGAGTLV 117 E +G +L +++ K L DAWFC W + P G + FPCY+W+EG G L Sbjct: 55 EYLGPLLFVKLRKRHL-------LKDDAWFCNWISVQGPGAGDEVRFPCYRWVEGNGVLS 107 Query: 118 LQEGTAKVSWADHHPVLQQQRQEELQARQEMYQWKAYNPGWPHCLDEKTVEDLELNIKYS 177 L EGT + D + Q+ R+EEL+ R+++Y+W + G + + DL ++ ++ Sbjct: 108 LPEGTGRTVGEDPQGLFQKHREEELEERRKLYRWGNWKDGLILNMAGAKLYDLPVDERFL 167 Query: 178 TAKNANFYLQAGSAFAEMKIKGLLDRKGLWRSLNEMKRIFNFRRTPAAEHAFEHWQEDAF 237 K +F + A++ IK L+ W+ L++ RIF ++ AE + W+EDA Sbjct: 168 EDKRVDFEVSLAKGLADLAIKDSLNVLTCWKDLDDFNRIFWCGQSKLAERVRDSWKEDAL 227 Query: 238 FASQFLNGLNPVLIRRCHYLPKNFPVTDAMVASVLGPGTS-LQAELEK----GSLFLVDH 292 F QFLNG NPV++RR +LP V PG LQA+LEK G+LF D Sbjct: 228 FGYQFLNGANPVVLRRSAHLPARL---------VFPPGMEELQAQLEKELEGGTLFEADF 278 Query: 293 GILSGIQTNVINGKPQFSAAPMTLLYQSPGCGPLLPLAIQLS--QTPGPNSPIFLPTDDK 350 +L GI+ NVI Q AAP+ +L P G LLP+ IQL +T P P+FLPTD Sbjct: 279 SLLDGIKANVILCSQQHLAAPLVMLKLQPD-GKLLPMVIQLQLPRTGSPPPPLFLPTDPP 337 Query: 351 WDWLLAKTWVRNAEFSFHEALTHLLHSHLLPEVFTLATLRQLPHCHPLFKLLIPHTRYTL 410 WLLAK WVR+++F HE +HLL HL+ EV +AT+R LP HP+FKL+IPH RYTL Sbjct: 338 MAWLLAKCWVRSSDFQLHELQSHLLRGHLMAEVIVVATMRCLPSIHPIFKLIIPHLRYTL 397 Query: 411 HINTLARELLIVPGQVVDRSTGIGIEGFSELIQRNMKQLNYSLLCLPEDIRTRGVEDIPG 470 IN AR L+ + D+ G G +L+++ L YS C P+D+ RG+ + Sbjct: 398 EINVRARTGLVSDMGIFDQIMSTGGGGHVQLLKQAGAFLTYSSFCPPDDLADRGLLGVKS 457 Query: 471 YYYRDDGMQIWGAVERFVSEIIGIYYPSDESVQDDRELQAWVREIFSKGFLNQESSGIPS 530 +Y D +++W + R+V I+ ++Y +D +V+DD ELQ W REI G + G P Sbjct: 458 SFYAQDALRLWEIIYRYVEGIVSLHYKTDVAVKDDPELQTWCREITEIGLQGAQDRGFPV 517 Query: 531 SLETREALVQYVTMVIFTCSAKHAAVSAGQFDSCAWMPNLPPSMQLPPPTSKGLATCEGF 590 SL+ R+ + +VTM IFTC+ +HA+V GQ D +W+PN P +M+LPPPT+K AT E Sbjct: 518 SLQARDQVCHFVTMCIFTCTGQHASVHLGQLDWYSWVPNAPCTMRLPPPTTKD-ATLETV 576 Query: 591 IATLPPVNATCDVILALWLLSKEPGDQRPLGTYPDEHFTEEAPRRSIATFQSRLAQISRG 650 +ATLP + + W L + +G + +E+F+ P+ + F+ LA + + Sbjct: 577 MATLPNFHQASLQMSITWQLGRRQPVMVAVGQHEEEYFSGPEPKAVLKKFREELAALDKE 636 Query: 651 IQERNQGLVLPYTYLDPPLIENSVSI 676 I+ RN L +PY YL P ++ENSV+I Sbjct: 637 IEIRNAKLDMPYEYLRPSVVENSVAI 662 >gi|239050813 lipoxygenase homology domains 1 isoform 1 [Homo sapiens] Length = 2211 Score = 41.6 bits (96), Expect = 0.002 Identities = 23/67 (34%), Positives = 39/67 (58%), Gaps = 1/67 (1%) Query: 3 EFRVRVSTGEAFGAGTWDKVSVSIVGTRGESPPLPLDNLGKEFTAGAEEDFQVTLPEDVG 62 ++ V+V TG+ GAGT V ++I G G++ L+N F GAE+ F + P D+G Sbjct: 173 KYEVKVYTGDVIGAGTDADVFINIFGEYGDTGERRLENEKDNFEKGAEDRFILDAP-DLG 231 Query: 63 RVLLLRV 69 +++ + V Sbjct: 232 QLMKINV 238 Score = 40.0 bits (92), Expect = 0.007 Identities = 23/69 (33%), Positives = 38/69 (55%), Gaps = 1/69 (1%) Query: 1 MAEFRVRVSTGEAFGAGTWDKVSVSIVGTRGESPPLPLDNLGKEFTAGAEEDFQVTLPED 60 + + V + TG+ GAGT +V + I G +G++ L L + K F +++ FQ+ D Sbjct: 813 LVHYEVEIWTGDVGGAGTSARVYMQIYGEKGKTEVLFLSSRSKVFERASKDTFQLE-AAD 871 Query: 61 VGRVLLLRV 69 VG V LR+ Sbjct: 872 VGEVYKLRL 880 Score = 35.8 bits (81), Expect = 0.13 Identities = 35/114 (30%), Positives = 46/114 (40%), Gaps = 22/114 (19%) Query: 6 VRVSTGEAFGAGTWDKVSVSIVGTRGESPPLPLDNLGKEFTAGAEEDFQVTLPEDVGRVL 65 V V TG+ GAGT K+ + + G RG N GK F G D GR Sbjct: 300 VTVFTGDVRGAGTKSKIYLVMYGARGNK------NSGKIFLEGG--------VFDRGRTD 345 Query: 66 LLRVHKAPPVLPLL------GPLAPD-AWFC-RWFQLTPPRGGHLLFPCYQWLE 111 + + A + PL G + + WFC + L P G FPC WL+ Sbjct: 346 IFHIELAVLLSPLSRVSVGHGNVGVNRGWFCEKVVILCPFTGIQQTFPCSNWLD 399 Score = 34.7 bits (78), Expect = 0.30 Identities = 31/110 (28%), Positives = 48/110 (43%), Gaps = 11/110 (10%) Query: 4 FRVRVSTGEAFGAGTWDKVSVSIVGTRGESPPLPLDNLGKE-FTAGAEEDFQVTLPEDVG 62 + V +TG+ GAGT V +++ G G SP L L + K F G + F+V +VG Sbjct: 45 YEVVTATGDVRGAGTDANVFITLFGENGLSPKLQLTSKSKSAFEKGNVDVFRVR-TNNVG 103 Query: 63 RVLLLRVHKAPPVLPLLGPLAPDAWFCRWFQLTPPRGGHL--LFPCYQWL 110 + +R+ L +W+ +T + HL F C WL Sbjct: 104 LIYKVRIEHDNTGLNA-------SWYLDHVIVTDMKRPHLRYYFNCNNWL 146 Score = 31.2 bits (69), Expect = 3.3 Identities = 28/115 (24%), Positives = 47/115 (40%), Gaps = 20/115 (17%) Query: 4 FRVRVSTGEAFGAGTWDKVSVSIVGTRGESPPLPLDNLGKEFTAGAEEDFQVTLPE--DV 61 F V + TG AGT V +++ GT+ ++ L + + ++ E D+ Sbjct: 1177 FSVTIKTGVKKNAGTDANVFITLFGTQDDTGMTLLKSSKTNSDKFERDSIEIFTVETLDL 1236 Query: 62 GRVLLLRV-----HKAPPVLPLLGPLAPDAWFCRWFQL-TPPRGGHLLFPCYQWL 110 G + +R+ KAP WF W ++ P G + FPC +WL Sbjct: 1237 GDLWKVRLGHDNTGKAP------------GWFVDWVEVDAPSLGKCMTFPCGRWL 1279 Score = 30.0 bits (66), Expect = 7.3 Identities = 30/119 (25%), Positives = 47/119 (39%), Gaps = 18/119 (15%) Query: 1 MAEFRVRVSTGEAFGAGTWDKVSVSIVGTRGESPPLPLDNLGKE---FTAGAEEDFQV-- 55 MA + V V TGE GAGT V + + G G++ L N F G ++F + Sbjct: 552 MARYHVTVCTGELEGAGTDANVYLCLFGDVGDTGERLLYNCRNNTDLFEKGNADEFTIES 611 Query: 56 TLPEDVGRVLLLRVHKAPPVLPLLGPLAPDAWFCRWFQLT---PPRGGHLLFPCYQWLE 111 +V RV + K + W+ + P ++ FPC +WL+ Sbjct: 612 VTMRNVRRVRIRHDGKG----------SGSGWYLDRVLVREEGQPESDNVEFPCLRWLD 660 >gi|118402590 myosin XV [Homo sapiens] Length = 3530 Score = 33.5 bits (75), Expect = 0.66 Identities = 19/39 (48%), Positives = 21/39 (53%), Gaps = 3/39 (7%) Query: 311 AAPMTLLYQSPG---CGPLLPLAIQLSQTPGPNSPIFLP 346 A+P L SPG C PL P + QLS GP P FLP Sbjct: 774 ASPQPSLRSSPGLGYCSPLAPPSPQLSLRTGPFQPPFLP 812 >gi|69885149 Fc receptor-like and mucin-like 1 [Homo sapiens] Length = 376 Score = 33.5 bits (75), Expect = 0.66 Identities = 21/54 (38%), Positives = 28/54 (51%), Gaps = 2/54 (3%) Query: 293 GILSGIQTNVINGKPQFSAAPMTLLYQSPGCGPLLPLAIQLSQTPGPNSPIFLP 346 G S +N PQ SAAP T ++P GPL P S+ PG +SP+ +P Sbjct: 279 GASSSAAPPTLNPAPQKSAAPGTAPEEAP--GPLPPPPTPSSEDPGFSSPLGMP 330 >gi|239756667 PREDICTED: hypothetical protein [Homo sapiens] Length = 484 Score = 32.7 bits (73), Expect = 1.1 Identities = 31/94 (32%), Positives = 43/94 (45%), Gaps = 5/94 (5%) Query: 11 GEAFGAGTWDKVSVSIVGTRGESP-PLPLDNLGKEFTAGAEEDFQVT---LPEDVGRVLL 66 GE G G ++ + G R E+ + LD LG+E E Q + E + RV L Sbjct: 117 GEQCGVGARARLGLEKSGPRAEAHLAVQLDVLGEERVDLGERAAQAAGMHVQEVLDRVHL 176 Query: 67 LRVHKAPPVLPLLGPLAPDAWFCRWFQLTPPRGG 100 + +HK P+L L P + DA R L PP G Sbjct: 177 VVLHKMLPILELPSPSSRDA-LHRGGPLPPPTHG 209 >gi|239751165 PREDICTED: hypothetical protein XP_002347739 [Homo sapiens] Length = 484 Score = 32.7 bits (73), Expect = 1.1 Identities = 31/94 (32%), Positives = 43/94 (45%), Gaps = 5/94 (5%) Query: 11 GEAFGAGTWDKVSVSIVGTRGESP-PLPLDNLGKEFTAGAEEDFQVT---LPEDVGRVLL 66 GE G G ++ + G R E+ + LD LG+E E Q + E + RV L Sbjct: 117 GEQCGVGARARLGLEKSGPRAEAHLAVQLDVLGEERVDLGERAAQAAGMHVQEVLDRVHL 176 Query: 67 LRVHKAPPVLPLLGPLAPDAWFCRWFQLTPPRGG 100 + +HK P+L L P + DA R L PP G Sbjct: 177 VVLHKMLPILELPSPSSRDA-LHRGGPLPPPTHG 209 >gi|239745650 PREDICTED: hypothetical protein XP_002344167 [Homo sapiens] Length = 484 Score = 32.7 bits (73), Expect = 1.1 Identities = 31/94 (32%), Positives = 43/94 (45%), Gaps = 5/94 (5%) Query: 11 GEAFGAGTWDKVSVSIVGTRGESP-PLPLDNLGKEFTAGAEEDFQVT---LPEDVGRVLL 66 GE G G ++ + G R E+ + LD LG+E E Q + E + RV L Sbjct: 117 GEQCGVGARARLGLEKSGPRAEAHLAVQLDVLGEERVDLGERAAQAAGMHVQEVLDRVHL 176 Query: 67 LRVHKAPPVLPLLGPLAPDAWFCRWFQLTPPRGG 100 + +HK P+L L P + DA R L PP G Sbjct: 177 VVLHKMLPILELPSPSSRDA-LHRGGPLPPPTHG 209 >gi|195972805 myocyte enhancer factor 2A isoform 4 [Homo sapiens] Length = 429 Score = 32.3 bits (72), Expect = 1.5 Identities = 31/94 (32%), Positives = 39/94 (41%), Gaps = 7/94 (7%) Query: 219 FRRTPAAEHAFEHWQEDAFFASQFLNGLNPVLIRRCHYLPKNFPVTDAMVASVLGPGTSL 278 F +P +E F ED+ F F G P L + + PVT S PG+SL Sbjct: 37 FEHSPLSEDRFSKLNEDSDFI--FKRG-PPGLPPQNFSMSVTVPVTSPNALSYTNPGSSL 93 Query: 279 QAELEKGSLFLVDHGILSGIQT----NVINGKPQ 308 + S L D +LS QT NV G PQ Sbjct: 94 VSPSLAASSTLTDSSMLSPPQTTLHRNVSPGAPQ 127 >gi|195972803 myocyte enhancer factor 2A isoform 3 [Homo sapiens] Length = 437 Score = 32.3 bits (72), Expect = 1.5 Identities = 31/94 (32%), Positives = 39/94 (41%), Gaps = 7/94 (7%) Query: 219 FRRTPAAEHAFEHWQEDAFFASQFLNGLNPVLIRRCHYLPKNFPVTDAMVASVLGPGTSL 278 F +P +E F ED+ F F G P L + + PVT S PG+SL Sbjct: 37 FEHSPLSEDRFSKLNEDSDFI--FKRG-PPGLPPQNFSMSVTVPVTSPNALSYTNPGSSL 93 Query: 279 QAELEKGSLFLVDHGILSGIQT----NVINGKPQ 308 + S L D +LS QT NV G PQ Sbjct: 94 VSPSLAASSTLTDSSMLSPPQTTLHRNVSPGAPQ 127 >gi|195972801 myocyte enhancer factor 2A isoform 2 [Homo sapiens] Length = 497 Score = 32.3 bits (72), Expect = 1.5 Identities = 31/94 (32%), Positives = 39/94 (41%), Gaps = 7/94 (7%) Query: 219 FRRTPAAEHAFEHWQEDAFFASQFLNGLNPVLIRRCHYLPKNFPVTDAMVASVLGPGTSL 278 F +P +E F ED+ F F G P L + + PVT S PG+SL Sbjct: 105 FEHSPLSEDRFSKLNEDSDFI--FKRG-PPGLPPQNFSMSVTVPVTSPNALSYTNPGSSL 161 Query: 279 QAELEKGSLFLVDHGILSGIQT----NVINGKPQ 308 + S L D +LS QT NV G PQ Sbjct: 162 VSPSLAASSTLTDSSMLSPPQTTLHRNVSPGAPQ 195 >gi|224458288 lipoxygenase homology domains 1 isoform 2 [Homo sapiens] Length = 1114 Score = 31.2 bits (69), Expect = 3.3 Identities = 28/115 (24%), Positives = 47/115 (40%), Gaps = 20/115 (17%) Query: 4 FRVRVSTGEAFGAGTWDKVSVSIVGTRGESPPLPLDNLGKEFTAGAEEDFQVTLPE--DV 61 F V + TG AGT V +++ GT+ ++ L + + ++ E D+ Sbjct: 66 FSVTIKTGVKKNAGTDANVFITLFGTQDDTGMTLLKSSKTNSDKFERDSIEIFTVETLDL 125 Query: 62 GRVLLLRV-----HKAPPVLPLLGPLAPDAWFCRWFQL-TPPRGGHLLFPCYQWL 110 G + +R+ KAP WF W ++ P G + FPC +WL Sbjct: 126 GDLWKVRLGHDNTGKAP------------GWFVDWVEVDAPSLGKCMTFPCGRWL 168 >gi|239755589 PREDICTED: hypothetical protein [Homo sapiens] Length = 356 Score = 30.8 bits (68), Expect = 4.3 Identities = 14/41 (34%), Positives = 23/41 (56%), Gaps = 4/41 (9%) Query: 550 SAKHAAVSAGQFDSCAWMP----NLPPSMQLPPPTSKGLAT 586 S++H+++S G+ D C + + PP+ LPPP G T Sbjct: 162 SSRHSSISEGEGDRCGFAEPPGGSSPPAPPLPPPPKPGSPT 202 >gi|155969714 nuclear protein, ataxia-telangiectasia locus [Homo sapiens] Length = 1427 Score = 30.4 bits (67), Expect = 5.6 Identities = 18/67 (26%), Positives = 33/67 (49%), Gaps = 6/67 (8%) Query: 128 ADHHPVLQQQRQEELQARQEMYQWKAYNPGWPHCLDEKTVEDLELNIKYSTAKNANFYLQ 187 +++H VL+Q+ QE Q KA+ P T + +++I + + N N + Q Sbjct: 402 SNNHDVLRQEDQENFSQISTSIQKKAFKTAVP------TEQKCDIDITFESVPNLNDFNQ 455 Query: 188 AGSAFAE 194 G++ AE Sbjct: 456 RGNSNAE 462 >gi|117168250 phospholipase C, epsilon 1 [Homo sapiens] Length = 2302 Score = 30.0 bits (66), Expect = 7.3 Identities = 17/54 (31%), Positives = 30/54 (55%), Gaps = 2/54 (3%) Query: 91 WFQLTPPRGGHLLFPCYQWLEGAGTL-VLQEGTAKVSWADHHPVLQQQRQEELQ 143 W + R G LL PC + +E T+ + Q+G+ ++S A +P+ R+EE + Sbjct: 361 WSYIDQKRNGPLL-PCGRVMEPPSTVEIRQDGSQRLSEAQWYPIYNAVRREETE 413 >gi|4557701 keratin 17 [Homo sapiens] Length = 432 Score = 30.0 bits (66), Expect = 7.3 Identities = 19/66 (28%), Positives = 32/66 (48%) Query: 126 SWADHHPVLQQQRQEELQARQEMYQWKAYNPGWPHCLDEKTVEDLELNIKYSTAKNANFY 185 S+ D L++ E ++ YQ +A P + +T+E+L+ I +T NAN Sbjct: 97 SYLDKVRALEEANTELEVKIRDWYQRQAPGPARDYSQYYRTIEELQNKILTATVDNANIL 156 Query: 186 LQAGSA 191 LQ +A Sbjct: 157 LQIDNA 162 >gi|5031653 breast carcinoma amplified sequence 2 [Homo sapiens] Length = 225 Score = 30.0 bits (66), Expect = 7.3 Identities = 17/58 (29%), Positives = 28/58 (48%), Gaps = 2/58 (3%) Query: 141 ELQARQEMYQWKAYNPGWPHCLD--EKTVEDLELNIKYSTAKNANFYLQAGSAFAEMK 196 EL ++ WK YN H ++ +K ++ L +I+ + N L AGS EM+ Sbjct: 125 ELMSQHGCNAWKVYNENLVHMIEHAQKELQKLRKHIQDLNWQRKNMQLTAGSKLREME 182 >gi|205360962 polycystin 1 isoform 2 precursor [Homo sapiens] Length = 4302 Score = 29.6 bits (65), Expect = 9.5 Identities = 18/67 (26%), Positives = 31/67 (46%), Gaps = 1/67 (1%) Query: 3 EFRVRVSTGEAFGAGTWDKVSVSIVGTRGESPPLPLDNLGKEFTAGAEEDFQVTLPEDVG 62 ++ + V TG G+GT V + + G S LD + F + + F++ P +G Sbjct: 3119 KYEILVKTGWGRGSGTTAHVGIMLYGVDSRSGHRHLDG-DRAFHRNSLDIFRIATPHSLG 3177 Query: 63 RVLLLRV 69 V +RV Sbjct: 3178 SVWKIRV 3184 >gi|205360954 polycystin 1 isoform 1 precursor [Homo sapiens] Length = 4303 Score = 29.6 bits (65), Expect = 9.5 Identities = 18/67 (26%), Positives = 31/67 (46%), Gaps = 1/67 (1%) Query: 3 EFRVRVSTGEAFGAGTWDKVSVSIVGTRGESPPLPLDNLGKEFTAGAEEDFQVTLPEDVG 62 ++ + V TG G+GT V + + G S LD + F + + F++ P +G Sbjct: 3119 KYEILVKTGWGRGSGTTAHVGIMLYGVDSRSGHRHLDG-DRAFHRNSLDIFRIATPHSLG 3177 Query: 63 RVLLLRV 69 V +RV Sbjct: 3178 SVWKIRV 3184 >gi|194248077 Kruppel-like factor 4 (gut) [Homo sapiens] Length = 479 Score = 29.6 bits (65), Expect = 9.5 Identities = 14/27 (51%), Positives = 14/27 (51%) Query: 320 SPGCGPLLPLAIQLSQTPGPNSPIFLP 346 S C P LPL PGPN P FLP Sbjct: 327 SRDCHPALPLPPGFHPHPGPNYPSFLP 353 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.320 0.137 0.432 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 28,908,933 Number of Sequences: 37866 Number of extensions: 1411166 Number of successful extensions: 3663 Number of sequences better than 10.0: 26 Number of HSP's better than 10.0 without gapping: 11 Number of HSP's successfully gapped in prelim test: 15 Number of HSP's that attempted gapping in prelim test: 3609 Number of HSP's gapped (non-prelim): 46 length of query: 676 length of database: 18,247,518 effective HSP length: 109 effective length of query: 567 effective length of database: 14,120,124 effective search space: 8006110308 effective search space used: 8006110308 T: 11 A: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.8 bits) S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.