Guide to the Human Genome
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Search of human proteins with 85067501

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|85067501 arachidonate 15-lipoxygenase, second type isoform d
[Homo sapiens]
         (676 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|85067501 arachidonate 15-lipoxygenase, second type isoform d ...  1392   0.0  
gi|85067499 arachidonate 15-lipoxygenase, second type isoform a ...  1320   0.0  
gi|85067503 arachidonate 15-lipoxygenase, second type isoform b ...  1210   0.0  
gi|182765464 arachidonate lipoxygenase 3 [Homo sapiens]               728   0.0  
gi|4502053 arachidonate 12-lipoxygenase, 12R type [Homo sapiens]      694   0.0  
gi|4502057 arachidonate 5-lipoxygenase [Homo sapiens]                 557   e-158
gi|154426292 arachidonate 12-lipoxygenase [Homo sapiens]              467   e-131
gi|40316937 arachidonate 15-lipoxygenase [Homo sapiens]               458   e-129
gi|239050813 lipoxygenase homology domains 1 isoform 1 [Homo sap...    42   0.002
gi|118402590 myosin XV [Homo sapiens]                                  33   0.66 
gi|69885149 Fc receptor-like and mucin-like 1 [Homo sapiens]           33   0.66 
gi|239756667 PREDICTED: hypothetical protein [Homo sapiens]            33   1.1  
gi|239751165 PREDICTED: hypothetical protein XP_002347739 [Homo ...    33   1.1  
gi|239745650 PREDICTED: hypothetical protein XP_002344167 [Homo ...    33   1.1  
gi|195972805 myocyte enhancer factor 2A isoform 4 [Homo sapiens]       32   1.5  
gi|195972803 myocyte enhancer factor 2A isoform 3 [Homo sapiens]       32   1.5  
gi|195972801 myocyte enhancer factor 2A isoform 2 [Homo sapiens]       32   1.5  
gi|224458288 lipoxygenase homology domains 1 isoform 2 [Homo sap...    31   3.3  
gi|239755589 PREDICTED: hypothetical protein [Homo sapiens]            31   4.3  
gi|155969714 nuclear protein,  ataxia-telangiectasia locus [Homo...    30   5.6  
gi|117168250 phospholipase C, epsilon 1 [Homo sapiens]                 30   7.3  
gi|4557701 keratin 17 [Homo sapiens]                                   30   7.3  
gi|5031653 breast carcinoma amplified sequence 2 [Homo sapiens]        30   7.3  
gi|205360962 polycystin 1 isoform 2 precursor [Homo sapiens]           30   9.5  
gi|205360954 polycystin 1 isoform 1 precursor [Homo sapiens]           30   9.5  
gi|194248077 Kruppel-like factor 4 (gut) [Homo sapiens]                30   9.5  

>gi|85067501 arachidonate 15-lipoxygenase, second type isoform d
           [Homo sapiens]
          Length = 676

 Score = 1392 bits (3603), Expect = 0.0
 Identities = 676/676 (100%), Positives = 676/676 (100%)

Query: 1   MAEFRVRVSTGEAFGAGTWDKVSVSIVGTRGESPPLPLDNLGKEFTAGAEEDFQVTLPED 60
           MAEFRVRVSTGEAFGAGTWDKVSVSIVGTRGESPPLPLDNLGKEFTAGAEEDFQVTLPED
Sbjct: 1   MAEFRVRVSTGEAFGAGTWDKVSVSIVGTRGESPPLPLDNLGKEFTAGAEEDFQVTLPED 60

Query: 61  VGRVLLLRVHKAPPVLPLLGPLAPDAWFCRWFQLTPPRGGHLLFPCYQWLEGAGTLVLQE 120
           VGRVLLLRVHKAPPVLPLLGPLAPDAWFCRWFQLTPPRGGHLLFPCYQWLEGAGTLVLQE
Sbjct: 61  VGRVLLLRVHKAPPVLPLLGPLAPDAWFCRWFQLTPPRGGHLLFPCYQWLEGAGTLVLQE 120

Query: 121 GTAKVSWADHHPVLQQQRQEELQARQEMYQWKAYNPGWPHCLDEKTVEDLELNIKYSTAK 180
           GTAKVSWADHHPVLQQQRQEELQARQEMYQWKAYNPGWPHCLDEKTVEDLELNIKYSTAK
Sbjct: 121 GTAKVSWADHHPVLQQQRQEELQARQEMYQWKAYNPGWPHCLDEKTVEDLELNIKYSTAK 180

Query: 181 NANFYLQAGSAFAEMKIKGLLDRKGLWRSLNEMKRIFNFRRTPAAEHAFEHWQEDAFFAS 240
           NANFYLQAGSAFAEMKIKGLLDRKGLWRSLNEMKRIFNFRRTPAAEHAFEHWQEDAFFAS
Sbjct: 181 NANFYLQAGSAFAEMKIKGLLDRKGLWRSLNEMKRIFNFRRTPAAEHAFEHWQEDAFFAS 240

Query: 241 QFLNGLNPVLIRRCHYLPKNFPVTDAMVASVLGPGTSLQAELEKGSLFLVDHGILSGIQT 300
           QFLNGLNPVLIRRCHYLPKNFPVTDAMVASVLGPGTSLQAELEKGSLFLVDHGILSGIQT
Sbjct: 241 QFLNGLNPVLIRRCHYLPKNFPVTDAMVASVLGPGTSLQAELEKGSLFLVDHGILSGIQT 300

Query: 301 NVINGKPQFSAAPMTLLYQSPGCGPLLPLAIQLSQTPGPNSPIFLPTDDKWDWLLAKTWV 360
           NVINGKPQFSAAPMTLLYQSPGCGPLLPLAIQLSQTPGPNSPIFLPTDDKWDWLLAKTWV
Sbjct: 301 NVINGKPQFSAAPMTLLYQSPGCGPLLPLAIQLSQTPGPNSPIFLPTDDKWDWLLAKTWV 360

Query: 361 RNAEFSFHEALTHLLHSHLLPEVFTLATLRQLPHCHPLFKLLIPHTRYTLHINTLARELL 420
           RNAEFSFHEALTHLLHSHLLPEVFTLATLRQLPHCHPLFKLLIPHTRYTLHINTLARELL
Sbjct: 361 RNAEFSFHEALTHLLHSHLLPEVFTLATLRQLPHCHPLFKLLIPHTRYTLHINTLARELL 420

Query: 421 IVPGQVVDRSTGIGIEGFSELIQRNMKQLNYSLLCLPEDIRTRGVEDIPGYYYRDDGMQI 480
           IVPGQVVDRSTGIGIEGFSELIQRNMKQLNYSLLCLPEDIRTRGVEDIPGYYYRDDGMQI
Sbjct: 421 IVPGQVVDRSTGIGIEGFSELIQRNMKQLNYSLLCLPEDIRTRGVEDIPGYYYRDDGMQI 480

Query: 481 WGAVERFVSEIIGIYYPSDESVQDDRELQAWVREIFSKGFLNQESSGIPSSLETREALVQ 540
           WGAVERFVSEIIGIYYPSDESVQDDRELQAWVREIFSKGFLNQESSGIPSSLETREALVQ
Sbjct: 481 WGAVERFVSEIIGIYYPSDESVQDDRELQAWVREIFSKGFLNQESSGIPSSLETREALVQ 540

Query: 541 YVTMVIFTCSAKHAAVSAGQFDSCAWMPNLPPSMQLPPPTSKGLATCEGFIATLPPVNAT 600
           YVTMVIFTCSAKHAAVSAGQFDSCAWMPNLPPSMQLPPPTSKGLATCEGFIATLPPVNAT
Sbjct: 541 YVTMVIFTCSAKHAAVSAGQFDSCAWMPNLPPSMQLPPPTSKGLATCEGFIATLPPVNAT 600

Query: 601 CDVILALWLLSKEPGDQRPLGTYPDEHFTEEAPRRSIATFQSRLAQISRGIQERNQGLVL 660
           CDVILALWLLSKEPGDQRPLGTYPDEHFTEEAPRRSIATFQSRLAQISRGIQERNQGLVL
Sbjct: 601 CDVILALWLLSKEPGDQRPLGTYPDEHFTEEAPRRSIATFQSRLAQISRGIQERNQGLVL 660

Query: 661 PYTYLDPPLIENSVSI 676
           PYTYLDPPLIENSVSI
Sbjct: 661 PYTYLDPPLIENSVSI 676


>gi|85067499 arachidonate 15-lipoxygenase, second type isoform a
           [Homo sapiens]
          Length = 647

 Score = 1320 bits (3416), Expect = 0.0
 Identities = 647/676 (95%), Positives = 647/676 (95%), Gaps = 29/676 (4%)

Query: 1   MAEFRVRVSTGEAFGAGTWDKVSVSIVGTRGESPPLPLDNLGKEFTAGAEEDFQVTLPED 60
           MAEFRVRVSTGEAFGAGTWDKVSVSIVGTRGESPPLPLDNLGKEFTAGAEEDFQVTLPED
Sbjct: 1   MAEFRVRVSTGEAFGAGTWDKVSVSIVGTRGESPPLPLDNLGKEFTAGAEEDFQVTLPED 60

Query: 61  VGRVLLLRVHKAPPVLPLLGPLAPDAWFCRWFQLTPPRGGHLLFPCYQWLEGAGTLVLQE 120
           VGRVLLLRVHKAPPVLPLLGPLAPDAWFCRWFQLTPPRGGHLLFPCYQWLEGAGTLVLQE
Sbjct: 61  VGRVLLLRVHKAPPVLPLLGPLAPDAWFCRWFQLTPPRGGHLLFPCYQWLEGAGTLVLQE 120

Query: 121 GTAKVSWADHHPVLQQQRQEELQARQEMYQWKAYNPGWPHCLDEKTVEDLELNIKYSTAK 180
           GTAKVSWADHHPVLQQQRQEELQARQEMYQWKAYNPGWPHCLDEKTVEDLELNIKYSTAK
Sbjct: 121 GTAKVSWADHHPVLQQQRQEELQARQEMYQWKAYNPGWPHCLDEKTVEDLELNIKYSTAK 180

Query: 181 NANFYLQAGSAFAEMKIKGLLDRKGLWRSLNEMKRIFNFRRTPAAEHAFEHWQEDAFFAS 240
           NANFYLQAGSAFAEMKIKGLLDRKGLWRSLNEMKRIFNFRRTPAAEHAFEHWQEDAFFAS
Sbjct: 181 NANFYLQAGSAFAEMKIKGLLDRKGLWRSLNEMKRIFNFRRTPAAEHAFEHWQEDAFFAS 240

Query: 241 QFLNGLNPVLIRRCHYLPKNFPVTDAMVASVLGPGTSLQAELEKGSLFLVDHGILSGIQT 300
           QFLNGLNPVLIRRCHYLPKNFPVTDAMVASVLGPGTSLQAELEKGSLFLVDHGILSGIQT
Sbjct: 241 QFLNGLNPVLIRRCHYLPKNFPVTDAMVASVLGPGTSLQAELEKGSLFLVDHGILSGIQT 300

Query: 301 NVINGKPQFSAAPMTLLYQSPGCGPLLPLAIQLSQTPGPNSPIFLPTDDKWDWLLAKTWV 360
           NVINGKPQFSAAPMTLLYQSPGCGPLLPLAIQLSQTPGPNSPIFLPTDDKWDWLLAKTWV
Sbjct: 301 NVINGKPQFSAAPMTLLYQSPGCGPLLPLAIQLSQTPGPNSPIFLPTDDKWDWLLAKTWV 360

Query: 361 RNAEFSFHEALTHLLHSHLLPEVFTLATLRQLPHCHPLFKLLIPHTRYTLHINTLARELL 420
           RNAEFSFHEALTHLLHSHLLPEVFTLATLRQLPHCHPLFK                    
Sbjct: 361 RNAEFSFHEALTHLLHSHLLPEVFTLATLRQLPHCHPLFK-------------------- 400

Query: 421 IVPGQVVDRSTGIGIEGFSELIQRNMKQLNYSLLCLPEDIRTRGVEDIPGYYYRDDGMQI 480
                    STGIGIEGFSELIQRNMKQLNYSLLCLPEDIRTRGVEDIPGYYYRDDGMQI
Sbjct: 401 ---------STGIGIEGFSELIQRNMKQLNYSLLCLPEDIRTRGVEDIPGYYYRDDGMQI 451

Query: 481 WGAVERFVSEIIGIYYPSDESVQDDRELQAWVREIFSKGFLNQESSGIPSSLETREALVQ 540
           WGAVERFVSEIIGIYYPSDESVQDDRELQAWVREIFSKGFLNQESSGIPSSLETREALVQ
Sbjct: 452 WGAVERFVSEIIGIYYPSDESVQDDRELQAWVREIFSKGFLNQESSGIPSSLETREALVQ 511

Query: 541 YVTMVIFTCSAKHAAVSAGQFDSCAWMPNLPPSMQLPPPTSKGLATCEGFIATLPPVNAT 600
           YVTMVIFTCSAKHAAVSAGQFDSCAWMPNLPPSMQLPPPTSKGLATCEGFIATLPPVNAT
Sbjct: 512 YVTMVIFTCSAKHAAVSAGQFDSCAWMPNLPPSMQLPPPTSKGLATCEGFIATLPPVNAT 571

Query: 601 CDVILALWLLSKEPGDQRPLGTYPDEHFTEEAPRRSIATFQSRLAQISRGIQERNQGLVL 660
           CDVILALWLLSKEPGDQRPLGTYPDEHFTEEAPRRSIATFQSRLAQISRGIQERNQGLVL
Sbjct: 572 CDVILALWLLSKEPGDQRPLGTYPDEHFTEEAPRRSIATFQSRLAQISRGIQERNQGLVL 631

Query: 661 PYTYLDPPLIENSVSI 676
           PYTYLDPPLIENSVSI
Sbjct: 632 PYTYLDPPLIENSVSI 647


>gi|85067503 arachidonate 15-lipoxygenase, second type isoform b
           [Homo sapiens]
          Length = 602

 Score = 1210 bits (3131), Expect = 0.0
 Identities = 602/676 (89%), Positives = 602/676 (89%), Gaps = 74/676 (10%)

Query: 1   MAEFRVRVSTGEAFGAGTWDKVSVSIVGTRGESPPLPLDNLGKEFTAGAEEDFQVTLPED 60
           MAEFRVRVSTGEAFGAGTWDKVSVSIVGTRGESPPLPLDNLGKEFTAGAEEDFQVTLPED
Sbjct: 1   MAEFRVRVSTGEAFGAGTWDKVSVSIVGTRGESPPLPLDNLGKEFTAGAEEDFQVTLPED 60

Query: 61  VGRVLLLRVHKAPPVLPLLGPLAPDAWFCRWFQLTPPRGGHLLFPCYQWLEGAGTLVLQE 120
           VGRVLLLRVHKAPPVLPLLGPLAPDAWFCRWFQLTPPRGGHLLFPCYQWLEGAGTLVLQE
Sbjct: 61  VGRVLLLRVHKAPPVLPLLGPLAPDAWFCRWFQLTPPRGGHLLFPCYQWLEGAGTLVLQE 120

Query: 121 GTAKVSWADHHPVLQQQRQEELQARQEMYQWKAYNPGWPHCLDEKTVEDLELNIKYSTAK 180
           GTAKVSWADHHPVLQQQRQEELQARQEMYQWKAYNPGWPHCLDEKTVEDLELNIKYSTAK
Sbjct: 121 GTAKVSWADHHPVLQQQRQEELQARQEMYQWKAYNPGWPHCLDEKTVEDLELNIKYSTAK 180

Query: 181 NANFYLQAGSAFAEMKIKGLLDRKGLWRSLNEMKRIFNFRRTPAAEHAFEHWQEDAFFAS 240
           NANFYLQAGSAFAEMKIKGLLDRKGLWRSLNEMKRIFNFRRTPAAEHAFEHWQEDAFFAS
Sbjct: 181 NANFYLQAGSAFAEMKIKGLLDRKGLWRSLNEMKRIFNFRRTPAAEHAFEHWQEDAFFAS 240

Query: 241 QFLNGLNPVLIRRCHYLPKNFPVTDAMVASVLGPGTSLQAELEKGSLFLVDHGILSGIQT 300
           QFLNGLNPVLIRRCHYLPKNFPVTDAMVASVLGPGTSLQAELEKGSLFLVDHGILSGIQT
Sbjct: 241 QFLNGLNPVLIRRCHYLPKNFPVTDAMVASVLGPGTSLQAELEKGSLFLVDHGILSGIQT 300

Query: 301 NVINGKPQFSAAPMTLLYQSPGCGPLLPLAIQLSQTPGPNSPIFLPTDDKWDWLLAKTWV 360
           NVINGKPQFSAAPMTLLYQSPGCGPLLPLAIQLSQTPGPNSPIFLPTDDKWDWLLAKTWV
Sbjct: 301 NVINGKPQFSAAPMTLLYQSPGCGPLLPLAIQLSQTPGPNSPIFLPTDDKWDWLLAKTWV 360

Query: 361 RNAEFSFHEALTHLLHSHLLPEVFTLATLRQLPHCHPLFKLLIPHTRYTLHINTLARELL 420
           RNAEFSFHEALTHLLHSHLLPEVFTLATLRQLPHCHPLFK                    
Sbjct: 361 RNAEFSFHEALTHLLHSHLLPEVFTLATLRQLPHCHPLFK-------------------- 400

Query: 421 IVPGQVVDRSTGIGIEGFSELIQRNMKQLNYSLLCLPEDIRTRGVEDIPGYYYRDDGMQI 480
                    STGIGIEGFSELIQRNMKQLNYSLLCLPEDIRTRGVEDIPGYYYRDDGMQI
Sbjct: 401 ---------STGIGIEGFSELIQRNMKQLNYSLLCLPEDIRTRGVEDIPGYYYRDDGMQI 451

Query: 481 WGAVERFVSEIIGIYYPSDESVQDDRELQAWVREIFSKGFLNQESSGIPSSLETREALVQ 540
           W                                             GIPSSLETREALVQ
Sbjct: 452 W---------------------------------------------GIPSSLETREALVQ 466

Query: 541 YVTMVIFTCSAKHAAVSAGQFDSCAWMPNLPPSMQLPPPTSKGLATCEGFIATLPPVNAT 600
           YVTMVIFTCSAKHAAVSAGQFDSCAWMPNLPPSMQLPPPTSKGLATCEGFIATLPPVNAT
Sbjct: 467 YVTMVIFTCSAKHAAVSAGQFDSCAWMPNLPPSMQLPPPTSKGLATCEGFIATLPPVNAT 526

Query: 601 CDVILALWLLSKEPGDQRPLGTYPDEHFTEEAPRRSIATFQSRLAQISRGIQERNQGLVL 660
           CDVILALWLLSKEPGDQRPLGTYPDEHFTEEAPRRSIATFQSRLAQISRGIQERNQGLVL
Sbjct: 527 CDVILALWLLSKEPGDQRPLGTYPDEHFTEEAPRRSIATFQSRLAQISRGIQERNQGLVL 586

Query: 661 PYTYLDPPLIENSVSI 676
           PYTYLDPPLIENSVSI
Sbjct: 587 PYTYLDPPLIENSVSI 602


>gi|182765464 arachidonate lipoxygenase 3 [Homo sapiens]
          Length = 711

 Score =  728 bits (1878), Expect = 0.0
 Identities = 369/717 (51%), Positives = 476/717 (66%), Gaps = 47/717 (6%)

Query: 1   MAEFRVRVSTGEAFGAGTWDKVSVSIVGTRGESPPLPLDNLGKEFTAGAEEDFQVTLPED 60
           MA +R+ V+TG    AGT D +SV++VGT GESP   LD +G++F  G+ + ++V    +
Sbjct: 1   MAVYRLCVTTGPYLRAGTLDNISVTLVGTCGESPKQRLDRMGRDFAPGSVQKYKVRCTAE 60

Query: 61  VGRVLLLRVHKAPPVLPLLGPLAPDAWFCRWFQLTPPRGGHLLFPCYQWLEGAGTLVLQE 120
           +G +LLLRVHK             D+W+C    +T P G    FPCYQW+EG  T+ L+ 
Sbjct: 61  LGELLLLRVHKERYAF-----FRKDSWYCSRICVTEPDGSVSHFPCYQWIEGYCTVELRP 115

Query: 121 GTAKVSWADHHPVLQQQRQEELQARQEMYQWKAYNPGWPHCLDEKTVEDLEL-------- 172
           GTA+    D  P+L   R  EL+ARQE Y+WK Y PG+P  +D  + +++E         
Sbjct: 116 GTARTICQDSLPLLLDHRTRELRARQECYRWKIYAPGFPCMVDVNSFQEMESDKKFALTK 175

Query: 173 ---------------------------------NIKYSTAKNANFYLQAGSAFAEMKIKG 199
                                            N++YS  K  +    A  A   MK++G
Sbjct: 176 TTTCVDQGDSSGNRYLPGFPMKIDIPSLMYMEPNVRYSATKTISLLFNAIPASLGMKLRG 235

Query: 200 LLDRKGLWRSLNEMKRIFNFRRTPAAEHAFEHWQEDAFFASQFLNGLNPVLIRRCHYLPK 259
           LLDRKG W+ L++M+ IF   +T   ++  EHW ED FF  Q+LNG+NPV++     LP 
Sbjct: 236 LLDRKGSWKKLDDMQNIFWCHKTFTTKYVTEHWCEDHFFGYQYLNGVNPVMLHCISSLPS 295

Query: 260 NFPVTDAMVASVLGPGTSLQAELEKGSLFLVDHGILSGIQTNVINGKPQFSAAPMTLLYQ 319
             PVT+ MVA +LG  T LQ ELE+G++FL D+ IL+   T+ +NG+ Q+ AAP+ LL+ 
Sbjct: 296 KLPVTNDMVAPLLGQDTCLQTELERGNIFLADYWILAEAPTHCLNGRQQYVAAPLCLLWL 355

Query: 320 SPGCGPLLPLAIQLSQTPGPNSPIFLPTDDKWDWLLAKTWVRNAEFSFHEALTHLLHSHL 379
           SP  G L+PLAIQLSQTPGP+SPIFLPTD +WDWLLAKTWVRN+EF  HE  TH L +HL
Sbjct: 356 SPQ-GALVPLAIQLSQTPGPDSPIFLPTDSEWDWLLAKTWVRNSEFLVHENNTHFLCTHL 414

Query: 380 LPEVFTLATLRQLPHCHPLFKLLIPHTRYTLHINTLARELLIVPGQVVDRSTGIGIEGFS 439
           L E F +ATLRQLP CHP++KLL+PHTRYTL +NT+AR  L+ P  +VD+ T IG +G  
Sbjct: 415 LCEAFAMATLRQLPLCHPIYKLLLPHTRYTLQVNTIARATLLNPEGLVDQVTSIGRQGLI 474

Query: 440 ELIQRNMKQLNYSLLCLPEDIRTRGVEDIPGYYYRDDGMQIWGAVERFVSEIIGIYYPSD 499
            L+   +    Y+  CLP+ +R RGV  IP Y+YRDDG++IW A+E FVSEI+G YYPSD
Sbjct: 475 YLMSTGLAHFTYTNFCLPDSLRARGVLAIPNYHYRDDGLKIWAAIESFVSEIVGYYYPSD 534

Query: 500 ESVQDDRELQAWVREIFSKGFLNQESSGIPSSLETREALVQYVTMVIFTCSAKHAAVSAG 559
            SVQ D ELQAW  EIF++ FL +ESSG PS L T   +V+++T +IF CSA+HAAV++G
Sbjct: 535 ASVQQDSELQAWTGEIFAQAFLGRESSGFPSRLCTPGEMVKFLTAIIFNCSAQHAAVNSG 594

Query: 560 QFDSCAWMPNLPPSMQLPPPTSKGLATCEGFIATLPPVNATCDVILALWLLSKEPGDQRP 619
           Q D  AWMPN P SM+ PPP +KG  T + ++ TLP VN +C+ +L  WL+S+EP DQRP
Sbjct: 595 QHDFGAWMPNAPSSMRQPPPQTKGTTTLKTYLDTLPEVNISCNNLLLFWLVSQEPKDQRP 654

Query: 620 LGTYPDEHFTEEAPRRSIATFQSRLAQISRGIQERNQGLVLPYTYLDPPLIENSVSI 676
           LGTYPDEHFTEEAPRRSIA FQSRLAQISR IQERNQGL LPYTYLDPPLIENSVSI
Sbjct: 655 LGTYPDEHFTEEAPRRSIAAFQSRLAQISRDIQERNQGLALPYTYLDPPLIENSVSI 711


>gi|4502053 arachidonate 12-lipoxygenase, 12R type [Homo sapiens]
          Length = 701

 Score =  694 bits (1792), Expect = 0.0
 Identities = 342/707 (48%), Positives = 468/707 (66%), Gaps = 37/707 (5%)

Query: 1   MAEFRVRVSTGEAFGAGTWDKVSVSIVGTRGESPPLPLDNLGKEFTAGAEEDFQVTLPED 60
           MA ++VRV+TG    +GT D +S++IVGT+GES    L++ G++F  GA   + V  P+D
Sbjct: 1   MATYKVRVATGTDLLSGTRDSISLTIVGTQGESHKQLLNHFGRDFATGAVGQYTVQCPQD 60

Query: 61  VGRVLLLRVHKAPPVLPLLGPLAPDAWFCRWFQLTPPRGGHLLFPCYQWLEGAGTLVLQE 120
           +G ++++R+HK             D W+C + Q+  P G    FP YQW++G  TL L+E
Sbjct: 61  LGELIIIRLHKERYAF-----FPKDPWYCNYVQICAPNGRIYHFPAYQWMDGYETLALRE 115

Query: 121 GTAKVSWADHHPVLQQQRQEELQARQEMYQWKA--------------------------- 153
            T K +  D  PVL + R+EE++A+Q+ Y W+                            
Sbjct: 116 ATGKTTADDSLPVLLEHRKEEIRAKQDFYHWRVFLPGLPSYVHIPSYRPPVRRHRNPNRP 175

Query: 154 ----YNPGWPHCLDEKTVEDLELNIKYSTAKNANFYLQAGSAFAEMKIKGLLDRKGLWRS 209
               Y PG+P  ++ K  + L LN++YS  K A+F+++ G      K++GLLD K  W+ 
Sbjct: 176 EWNGYIPGFPILINFKATKFLNLNLRYSFLKTASFFVRLGPMALAFKVRGLLDCKHSWKR 235

Query: 210 LNEMKRIFNFRRTPAAEHAFEHWQEDAFFASQFLNGLNPVLIRRCHYLPKNFPVTDAMVA 269
           L ++++IF  +++  +E+  EHW ED FF  Q+LNG+NP LIRRC  +P  FPVTD MVA
Sbjct: 236 LKDIRKIFPGKKSVVSEYVAEHWAEDTFFGYQYLNGVNPGLIRRCTRIPDKFPVTDDMVA 295

Query: 270 SVLGPGTSLQAELEKGSLFLVDHGILSGIQTNVINGKPQFSAAPMTLLYQSPGCGPLLPL 329
             LG GT LQAELEKG+++L D+ I+ GI T  ++G+ Q   AP+ LL+  P  G ++P+
Sbjct: 296 PFLGEGTCLQAELEKGNIYLADYRIMEGIPTVELSGRKQHHCAPLCLLHFGPE-GKMMPI 354

Query: 330 AIQLSQTPGPNSPIFLPTDDKWDWLLAKTWVRNAEFSFHEALTHLLHSHLLPEVFTLATL 389
           AIQLSQTPGP+ PIFLP+D +WDWLLAKTWVR AEF  HEA+ HLL +HL+ E F LA L
Sbjct: 355 AIQLSQTPGPDCPIFLPSDSEWDWLLAKTWVRYAEFYSHEAIAHLLETHLIAEAFCLALL 414

Query: 390 RQLPHCHPLFKLLIPHTRYTLHINTLARELLIVPGQVVDRSTGIGIEGFSELIQRNMKQL 449
           R LP CHPL+KLLIPHTRYT+ IN++ R +L+  G +  +   +G+EGF+ ++ R + +L
Sbjct: 415 RNLPMCHPLYKLLIPHTRYTVQINSIGRAVLLNEGGLSAKGMSLGVEGFAGVMVRALSEL 474

Query: 450 NYSLLCLPEDIRTRGVEDIPGYYYRDDGMQIWGAVERFVSEIIGIYYPSDESVQDDRELQ 509
            Y  L LP D   RGV+D+PGYYYRDD + +W A+E++V+EII  YYPSD +V+ D ELQ
Sbjct: 475 TYDSLYLPNDFVERGVQDLPGYYYRDDSLAVWNALEKYVTEIITYYYPSDAAVEGDPELQ 534

Query: 510 AWVREIFSKGFLNQESSGIPSSLETREALVQYVTMVIFTCSAKHAAVSAGQFDSCAWMPN 569
           +WV+EIF +  L +ESSG P  L T   L++YVT+VI+TCSAKHAAV+ GQ +  AWMPN
Sbjct: 535 SWVQEIFKECLLGRESSGFPRCLRTVPELIRYVTIVIYTCSAKHAAVNTGQMEFTAWMPN 594

Query: 570 LPPSMQLPPPTSKGLATCEGFIATLPPVNATCDVILALWLLSKEPGDQRPLGTYPDEHFT 629
            P SM+ PP  +KGL T E F+ TLP V  TC  +L LW LS+EP D+RPLG +PD HF 
Sbjct: 595 FPASMRNPPIQTKGLTTLETFMDTLPDVKTTCITLLVLWTLSREPDDRRPLGHFPDIHFV 654

Query: 630 EEAPRRSIATFQSRLAQISRGIQERNQGLVLPYTYLDPPLIENSVSI 676
           EEAPRRSI  F+ RL QIS  I++RN+ L +PY YLDP LIENS+SI
Sbjct: 655 EEAPRRSIEAFRQRLNQISHDIRQRNKCLPIPYYYLDPVLIENSISI 701


>gi|4502057 arachidonate 5-lipoxygenase [Homo sapiens]
          Length = 674

 Score =  557 bits (1435), Expect = e-158
 Identities = 288/682 (42%), Positives = 426/682 (62%), Gaps = 14/682 (2%)

Query: 1   MAEFRVRVSTGEAFGAGTWDKVSVSIVGTRGESPPLPLDN-LGKEFTAGAEEDFQVTLPE 59
           M  + V V+TG  + AGT D + +S+VG+ G S    LD     +F  GA + + VT+ E
Sbjct: 1   MPSYTVTVATGSQWFAGTDDYIYLSLVGSAGCSEKHLLDKPFYNDFERGAVDSYDVTVDE 60

Query: 60  DVGRVLLLRVHKAPPVLPLLGPLAPDAWFCRWFQLTPPRGGHLLFPCYQWLEGAGTLVLQ 119
           ++G + L+R+ K    L        D W+ ++  L  P G ++ FPCY+W+ G   +VL+
Sbjct: 61  ELGEIQLVRIEKRKYWLN-------DDWYLKYITLKTPHGDYIEFPCYRWITGDVEVVLR 113

Query: 120 EGTAKVSWADHHPVLQQQRQEELQARQEMYQWKAYNPGWPHCLDEKTVEDLELNIKYSTA 179
           +G AK++  D   +L+Q R++EL+ RQ+ Y+W  +NPG+P  +D K  +DL  +I++ + 
Sbjct: 114 DGRAKLARDDQIHILKQHRRKELETRQKQYRWMEWNPGFPLSIDAKCHKDLPRDIQFDSE 173

Query: 180 KNANFYLQAGSAFAEMKIKGLLDR-KGLWRSLNEMKRIFNFRRTPAAEHAFEHWQEDAFF 238
           K  +F L    A   + I   +   +  W    + ++IF       +E    HWQED  F
Sbjct: 174 KGVDFVLNYSKAMENLFINRFMHMFQSSWNDFADFEKIFVKISNTISERVMNHWQEDLMF 233

Query: 239 ASQFLNGLNPVLIRRCHYLPKNFPVTDAMVASVLGPGTSLQAELEKGSLFLVDHGILSGI 298
             QFLNG NPVLIRRC  LP+  PVT  MV   L    SL+ E+++G++F+VD  +L GI
Sbjct: 234 GYQFLNGCNPVLIRRCTELPEKLPVTTEMVECSLERQLSLEQEVQQGNIFIVDFELLDGI 293

Query: 299 QTNVINGKP-QFSAAPMTLLYQSPGCGPLLPLAIQLSQTPGPNSPIFLPTDDKWDWLLAK 357
             N  +    QF AAP+ LLY++     ++P+AIQL+Q PG  +PIFLP+D K+DWLLAK
Sbjct: 294 DANKTDPCTLQFLAAPICLLYKNLA-NKIVPIAIQLNQIPGDENPIFLPSDAKYDWLLAK 352

Query: 358 TWVRNAEFSFHEALTHLLHSHLLPEVFTLATLRQLPHCHPLFKLLIPHTRYTLHINTLAR 417
            WVR+++F  H+ +THLL +HL+ EVF +A  RQLP  HP+FKLL+ H R+T+ INT AR
Sbjct: 353 IWVRSSDFHVHQTITHLLRTHLVSEVFGIAMYRQLPAVHPIFKLLVAHVRFTIAINTKAR 412

Query: 418 ELLIVPGQVVDRSTGIGIEGFSELIQRNMKQLNYSLLCLPEDIRTRGVE---DIPGYYYR 474
           E LI    + D++   G  G  +++QR MK L Y+ LC PE I+ RG+E   DIP Y+YR
Sbjct: 413 EQLICECGLFDKANATGGGGHVQMVQRAMKDLTYASLCFPEAIKARGMESKEDIPYYFYR 472

Query: 475 DDGMQIWGAVERFVSEIIGIYYPSDESVQDDRELQAWVREIFSKGFLNQESSGIPSSLET 534
           DDG+ +W A+  F +E++ IYY  D+ V++D ELQ +V +++  G   ++SSG P S+++
Sbjct: 473 DDGLLVWEAIRTFTAEVVDIYYEGDQVVEEDPELQDFVNDVYVYGMRGRKSSGFPKSVKS 532

Query: 535 REALVQYVTMVIFTCSAKHAAVSAGQFDSCAWMPNLPPSMQLPPPTSKGLATCEGFIATL 594
           RE L +Y+T+VIFT SA+HAAV+ GQ+D C+W+PN PP+M+ PPPT+KG+ T E  + TL
Sbjct: 533 REQLSEYLTVVIFTASAQHAAVNFGQYDWCSWIPNAPPTMRAPPPTAKGVVTIEQIVDTL 592

Query: 595 PPVNATCDVILALWLLSKEPGDQRPLGTYPDEHFTEEAPRRSIATFQSRLAQISRGIQER 654
           P    +C  + A+W LS+   ++  LG YP+EHF E+  + ++A F+  L  I   I ER
Sbjct: 593 PDRGRSCWHLGAVWALSQFQENELFLGMYPEEHFIEKPVKEAMARFRKNLEAIVSVIAER 652

Query: 655 NQGLVLPYTYLDPPLIENSVSI 676
           N+   LPY YL P  I NSV+I
Sbjct: 653 NKKKQLPYYYLSPDRIPNSVAI 674


>gi|154426292 arachidonate 12-lipoxygenase [Homo sapiens]
          Length = 663

 Score =  467 bits (1202), Expect = e-131
 Identities = 255/680 (37%), Positives = 384/680 (56%), Gaps = 21/680 (3%)

Query: 1   MAEFRVRVSTGEAFGAGTWDKVSVSIVGTRGESPPLPLDNLGKEFTAGAEEDFQVTLPED 60
           M  +R+RV+TG    +G++++V + +VGTRGE+       L      G EE+F   + ED
Sbjct: 1   MGRYRIRVATGAWLFSGSYNRVQLWLVGTRGEAEL----ELQLRPARGEEEEFDHDVAED 56

Query: 61  VGRVLLLRVHKAPPVLPLLGPLAPDAWFCRWFQLTPPRG-GHLLFPCYQWLEGAGTLVLQ 119
           +G +  +R+ K          L  DAWFC    +  P     + FPCY+W++G   L L 
Sbjct: 57  LGLLQFVRLRKHHW-------LVDDAWFCDRITVQGPGACAEVAFPCYRWVQGEDILSLP 109

Query: 120 EGTAKVSWADHHPVLQQQRQEELQARQEMYQWKAYNPGWPHCLDEKTVEDLELNIKYSTA 179
           EGTA++   +   + Q+ R++EL+ RQ++Y W  +  G P  +     +DL  N+++   
Sbjct: 110 EGTARLPGDNALDMFQKHREKELKDRQQIYCWATWKEGLPLTIAADRKDDLPPNMRFHEE 169

Query: 180 KNANFYLQAGSAFAEMKIKGLLDRKGLWRSLNEMKRIFNFRRTPAAEHAFEHWQEDAFFA 239
           K  +F     +   EM +K +      W  L +  +IF  +++  AE   + WQ+D  F+
Sbjct: 170 KRLDFEWTLKAGALEMALKRVYTLLSSWNCLEDFDQIFWGQKSALAEKVRQCWQDDELFS 229

Query: 240 SQFLNGLNPVLIRRCHYLPKNFPVTDAMVASVLGPGTSLQAELEKGSLFLVDHGILSGIQ 299
            QFLNG NP+L+RR   LP    +   M          L+ EL+ GSLF  D  +L GI 
Sbjct: 230 YQFLNGANPMLLRRSTSLPSRLVLPSGMEELQ----AQLEKELQNGSLFEADFILLDGIP 285

Query: 300 TNVINGKPQFSAAPMTLLYQSPGCGPLLPLAIQLSQTPGPNSP---IFLPTDDKWDWLLA 356
            NVI G+ Q+ AAP+ +L   P  G L P+ IQ+ Q P P+SP   +FLP+D    WLLA
Sbjct: 286 ANVIRGEKQYLAAPLVMLKMEPN-GKLQPMVIQI-QPPNPSSPTPTLFLPSDPPLAWLLA 343

Query: 357 KTWVRNAEFSFHEALTHLLHSHLLPEVFTLATLRQLPHCHPLFKLLIPHTRYTLHINTLA 416
           K+WVRN++F  HE   HLL++HL+ EV  +AT+R LP  HP+FK LIPH RYT+ INT A
Sbjct: 344 KSWVRNSDFQLHEIQYHLLNTHLVAEVIAVATMRCLPGLHPIFKFLIPHIRYTMEINTRA 403

Query: 417 RELLIVPGQVVDRSTGIGIEGFSELIQRNMKQLNYSLLCLPEDIRTRGVEDIPGYYYRDD 476
           R  LI  G + D++   G  G  +L++R   QL Y  LC P+D+  RG+  +PG  Y  D
Sbjct: 404 RTQLISDGGIFDKAVSTGGGGHVQLLRRAAAQLTYCSLCPPDDLADRGLLGLPGALYAHD 463

Query: 477 GMQIWGAVERFVSEIIGIYYPSDESVQDDRELQAWVREIFSKGFLNQESSGIPSSLETRE 536
            +++W  + R+V  I+ ++Y  D+ V+ D ELQAW REI   G    +  G P S +++ 
Sbjct: 464 ALRLWEIIARYVEGIVHLFYQRDDIVKGDPELQAWCREITEVGLCQAQDRGFPVSFQSQS 523

Query: 537 ALVQYVTMVIFTCSAKHAAVSAGQFDSCAWMPNLPPSMQLPPPTSKGLATCEGFIATLPP 596
            L  ++TM +FTC+A+HAA++ GQ D  AW+PN P +M++PPPT+K   T    + +LP 
Sbjct: 524 QLCHFLTMCVFTCTAQHAAINQGQLDWYAWVPNAPCTMRMPPPTTKEDVTMATVMGSLPD 583

Query: 597 VNATCDVILALWLLSKEPGDQRPLGTYPDEHFTEEAPRRSIATFQSRLAQISRGIQERNQ 656
           V   C  +   W LS+   D  PLG + +++F+   P+  +  F++ L ++ + I  RN+
Sbjct: 584 VRQACLQMAISWHLSRRQPDMVPLGHHKEKYFSGPKPKAVLNQFRTDLEKLEKEITARNE 643

Query: 657 GLVLPYTYLDPPLIENSVSI 676
            L  PY YL P  IENSV+I
Sbjct: 644 QLDWPYEYLKPSCIENSVTI 663


>gi|40316937 arachidonate 15-lipoxygenase [Homo sapiens]
          Length = 662

 Score =  458 bits (1178), Expect = e-129
 Identities = 259/686 (37%), Positives = 384/686 (55%), Gaps = 34/686 (4%)

Query: 1   MAEFRVRVSTGEAFGAGTWDKVSVSIVGTRGESPPLPLDNLGKEF--TAGAEEDFQVTLP 58
           M  +R+RVSTG +  AG+ ++V + +VG  GE+       LGK      G E + +V +P
Sbjct: 1   MGLYRIRVSTGASLYAGSNNQVQLWLVGQHGEAA------LGKRLWPARGKETELKVEVP 54

Query: 59  EDVGRVLLLRVHKAPPVLPLLGPLAPDAWFCRWFQLTPPRGG-HLLFPCYQWLEGAGTLV 117
           E +G +L +++ K          L  DAWFC W  +  P  G  + FPCY+W+EG G L 
Sbjct: 55  EYLGPLLFVKLRKRHL-------LKDDAWFCNWISVQGPGAGDEVRFPCYRWVEGNGVLS 107

Query: 118 LQEGTAKVSWADHHPVLQQQRQEELQARQEMYQWKAYNPGWPHCLDEKTVEDLELNIKYS 177
           L EGT +    D   + Q+ R+EEL+ R+++Y+W  +  G    +    + DL ++ ++ 
Sbjct: 108 LPEGTGRTVGEDPQGLFQKHREEELEERRKLYRWGNWKDGLILNMAGAKLYDLPVDERFL 167

Query: 178 TAKNANFYLQAGSAFAEMKIKGLLDRKGLWRSLNEMKRIFNFRRTPAAEHAFEHWQEDAF 237
             K  +F +      A++ IK  L+    W+ L++  RIF   ++  AE   + W+EDA 
Sbjct: 168 EDKRVDFEVSLAKGLADLAIKDSLNVLTCWKDLDDFNRIFWCGQSKLAERVRDSWKEDAL 227

Query: 238 FASQFLNGLNPVLIRRCHYLPKNFPVTDAMVASVLGPGTS-LQAELEK----GSLFLVDH 292
           F  QFLNG NPV++RR  +LP            V  PG   LQA+LEK    G+LF  D 
Sbjct: 228 FGYQFLNGANPVVLRRSAHLPARL---------VFPPGMEELQAQLEKELEGGTLFEADF 278

Query: 293 GILSGIQTNVINGKPQFSAAPMTLLYQSPGCGPLLPLAIQLS--QTPGPNSPIFLPTDDK 350
            +L GI+ NVI    Q  AAP+ +L   P  G LLP+ IQL   +T  P  P+FLPTD  
Sbjct: 279 SLLDGIKANVILCSQQHLAAPLVMLKLQPD-GKLLPMVIQLQLPRTGSPPPPLFLPTDPP 337

Query: 351 WDWLLAKTWVRNAEFSFHEALTHLLHSHLLPEVFTLATLRQLPHCHPLFKLLIPHTRYTL 410
             WLLAK WVR+++F  HE  +HLL  HL+ EV  +AT+R LP  HP+FKL+IPH RYTL
Sbjct: 338 MAWLLAKCWVRSSDFQLHELQSHLLRGHLMAEVIVVATMRCLPSIHPIFKLIIPHLRYTL 397

Query: 411 HINTLARELLIVPGQVVDRSTGIGIEGFSELIQRNMKQLNYSLLCLPEDIRTRGVEDIPG 470
            IN  AR  L+    + D+    G  G  +L+++    L YS  C P+D+  RG+  +  
Sbjct: 398 EINVRARTGLVSDMGIFDQIMSTGGGGHVQLLKQAGAFLTYSSFCPPDDLADRGLLGVKS 457

Query: 471 YYYRDDGMQIWGAVERFVSEIIGIYYPSDESVQDDRELQAWVREIFSKGFLNQESSGIPS 530
            +Y  D +++W  + R+V  I+ ++Y +D +V+DD ELQ W REI   G    +  G P 
Sbjct: 458 SFYAQDALRLWEIIYRYVEGIVSLHYKTDVAVKDDPELQTWCREITEIGLQGAQDRGFPV 517

Query: 531 SLETREALVQYVTMVIFTCSAKHAAVSAGQFDSCAWMPNLPPSMQLPPPTSKGLATCEGF 590
           SL+ R+ +  +VTM IFTC+ +HA+V  GQ D  +W+PN P +M+LPPPT+K  AT E  
Sbjct: 518 SLQARDQVCHFVTMCIFTCTGQHASVHLGQLDWYSWVPNAPCTMRLPPPTTKD-ATLETV 576

Query: 591 IATLPPVNATCDVILALWLLSKEPGDQRPLGTYPDEHFTEEAPRRSIATFQSRLAQISRG 650
           +ATLP  +     +   W L +       +G + +E+F+   P+  +  F+  LA + + 
Sbjct: 577 MATLPNFHQASLQMSITWQLGRRQPVMVAVGQHEEEYFSGPEPKAVLKKFREELAALDKE 636

Query: 651 IQERNQGLVLPYTYLDPPLIENSVSI 676
           I+ RN  L +PY YL P ++ENSV+I
Sbjct: 637 IEIRNAKLDMPYEYLRPSVVENSVAI 662


>gi|239050813 lipoxygenase homology domains 1 isoform 1 [Homo
           sapiens]
          Length = 2211

 Score = 41.6 bits (96), Expect = 0.002
 Identities = 23/67 (34%), Positives = 39/67 (58%), Gaps = 1/67 (1%)

Query: 3   EFRVRVSTGEAFGAGTWDKVSVSIVGTRGESPPLPLDNLGKEFTAGAEEDFQVTLPEDVG 62
           ++ V+V TG+  GAGT   V ++I G  G++    L+N    F  GAE+ F +  P D+G
Sbjct: 173 KYEVKVYTGDVIGAGTDADVFINIFGEYGDTGERRLENEKDNFEKGAEDRFILDAP-DLG 231

Query: 63  RVLLLRV 69
           +++ + V
Sbjct: 232 QLMKINV 238



 Score = 40.0 bits (92), Expect = 0.007
 Identities = 23/69 (33%), Positives = 38/69 (55%), Gaps = 1/69 (1%)

Query: 1   MAEFRVRVSTGEAFGAGTWDKVSVSIVGTRGESPPLPLDNLGKEFTAGAEEDFQVTLPED 60
           +  + V + TG+  GAGT  +V + I G +G++  L L +  K F   +++ FQ+    D
Sbjct: 813 LVHYEVEIWTGDVGGAGTSARVYMQIYGEKGKTEVLFLSSRSKVFERASKDTFQLE-AAD 871

Query: 61  VGRVLLLRV 69
           VG V  LR+
Sbjct: 872 VGEVYKLRL 880



 Score = 35.8 bits (81), Expect = 0.13
 Identities = 35/114 (30%), Positives = 46/114 (40%), Gaps = 22/114 (19%)

Query: 6   VRVSTGEAFGAGTWDKVSVSIVGTRGESPPLPLDNLGKEFTAGAEEDFQVTLPEDVGRVL 65
           V V TG+  GAGT  K+ + + G RG        N GK F  G           D GR  
Sbjct: 300 VTVFTGDVRGAGTKSKIYLVMYGARGNK------NSGKIFLEGG--------VFDRGRTD 345

Query: 66  LLRVHKAPPVLPLL------GPLAPD-AWFC-RWFQLTPPRGGHLLFPCYQWLE 111
           +  +  A  + PL       G +  +  WFC +   L P  G    FPC  WL+
Sbjct: 346 IFHIELAVLLSPLSRVSVGHGNVGVNRGWFCEKVVILCPFTGIQQTFPCSNWLD 399



 Score = 34.7 bits (78), Expect = 0.30
 Identities = 31/110 (28%), Positives = 48/110 (43%), Gaps = 11/110 (10%)

Query: 4   FRVRVSTGEAFGAGTWDKVSVSIVGTRGESPPLPLDNLGKE-FTAGAEEDFQVTLPEDVG 62
           + V  +TG+  GAGT   V +++ G  G SP L L +  K  F  G  + F+V    +VG
Sbjct: 45  YEVVTATGDVRGAGTDANVFITLFGENGLSPKLQLTSKSKSAFEKGNVDVFRVR-TNNVG 103

Query: 63  RVLLLRVHKAPPVLPLLGPLAPDAWFCRWFQLTPPRGGHL--LFPCYQWL 110
            +  +R+      L         +W+     +T  +  HL   F C  WL
Sbjct: 104 LIYKVRIEHDNTGLNA-------SWYLDHVIVTDMKRPHLRYYFNCNNWL 146



 Score = 31.2 bits (69), Expect = 3.3
 Identities = 28/115 (24%), Positives = 47/115 (40%), Gaps = 20/115 (17%)

Query: 4    FRVRVSTGEAFGAGTWDKVSVSIVGTRGESPPLPLDNLGKEFTAGAEEDFQVTLPE--DV 61
            F V + TG    AGT   V +++ GT+ ++    L +          +  ++   E  D+
Sbjct: 1177 FSVTIKTGVKKNAGTDANVFITLFGTQDDTGMTLLKSSKTNSDKFERDSIEIFTVETLDL 1236

Query: 62   GRVLLLRV-----HKAPPVLPLLGPLAPDAWFCRWFQL-TPPRGGHLLFPCYQWL 110
            G +  +R+      KAP             WF  W ++  P  G  + FPC +WL
Sbjct: 1237 GDLWKVRLGHDNTGKAP------------GWFVDWVEVDAPSLGKCMTFPCGRWL 1279



 Score = 30.0 bits (66), Expect = 7.3
 Identities = 30/119 (25%), Positives = 47/119 (39%), Gaps = 18/119 (15%)

Query: 1   MAEFRVRVSTGEAFGAGTWDKVSVSIVGTRGESPPLPLDNLGKE---FTAGAEEDFQV-- 55
           MA + V V TGE  GAGT   V + + G  G++    L N       F  G  ++F +  
Sbjct: 552 MARYHVTVCTGELEGAGTDANVYLCLFGDVGDTGERLLYNCRNNTDLFEKGNADEFTIES 611

Query: 56  TLPEDVGRVLLLRVHKAPPVLPLLGPLAPDAWFCRWFQLT---PPRGGHLLFPCYQWLE 111
               +V RV +    K           +   W+     +     P   ++ FPC +WL+
Sbjct: 612 VTMRNVRRVRIRHDGKG----------SGSGWYLDRVLVREEGQPESDNVEFPCLRWLD 660


>gi|118402590 myosin XV [Homo sapiens]
          Length = 3530

 Score = 33.5 bits (75), Expect = 0.66
 Identities = 19/39 (48%), Positives = 21/39 (53%), Gaps = 3/39 (7%)

Query: 311 AAPMTLLYQSPG---CGPLLPLAIQLSQTPGPNSPIFLP 346
           A+P   L  SPG   C PL P + QLS   GP  P FLP
Sbjct: 774 ASPQPSLRSSPGLGYCSPLAPPSPQLSLRTGPFQPPFLP 812


>gi|69885149 Fc receptor-like and mucin-like 1 [Homo sapiens]
          Length = 376

 Score = 33.5 bits (75), Expect = 0.66
 Identities = 21/54 (38%), Positives = 28/54 (51%), Gaps = 2/54 (3%)

Query: 293 GILSGIQTNVINGKPQFSAAPMTLLYQSPGCGPLLPLAIQLSQTPGPNSPIFLP 346
           G  S      +N  PQ SAAP T   ++P  GPL P     S+ PG +SP+ +P
Sbjct: 279 GASSSAAPPTLNPAPQKSAAPGTAPEEAP--GPLPPPPTPSSEDPGFSSPLGMP 330


>gi|239756667 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 484

 Score = 32.7 bits (73), Expect = 1.1
 Identities = 31/94 (32%), Positives = 43/94 (45%), Gaps = 5/94 (5%)

Query: 11  GEAFGAGTWDKVSVSIVGTRGESP-PLPLDNLGKEFTAGAEEDFQVT---LPEDVGRVLL 66
           GE  G G   ++ +   G R E+   + LD LG+E     E   Q     + E + RV L
Sbjct: 117 GEQCGVGARARLGLEKSGPRAEAHLAVQLDVLGEERVDLGERAAQAAGMHVQEVLDRVHL 176

Query: 67  LRVHKAPPVLPLLGPLAPDAWFCRWFQLTPPRGG 100
           + +HK  P+L L  P + DA   R   L PP  G
Sbjct: 177 VVLHKMLPILELPSPSSRDA-LHRGGPLPPPTHG 209


>gi|239751165 PREDICTED: hypothetical protein XP_002347739 [Homo
           sapiens]
          Length = 484

 Score = 32.7 bits (73), Expect = 1.1
 Identities = 31/94 (32%), Positives = 43/94 (45%), Gaps = 5/94 (5%)

Query: 11  GEAFGAGTWDKVSVSIVGTRGESP-PLPLDNLGKEFTAGAEEDFQVT---LPEDVGRVLL 66
           GE  G G   ++ +   G R E+   + LD LG+E     E   Q     + E + RV L
Sbjct: 117 GEQCGVGARARLGLEKSGPRAEAHLAVQLDVLGEERVDLGERAAQAAGMHVQEVLDRVHL 176

Query: 67  LRVHKAPPVLPLLGPLAPDAWFCRWFQLTPPRGG 100
           + +HK  P+L L  P + DA   R   L PP  G
Sbjct: 177 VVLHKMLPILELPSPSSRDA-LHRGGPLPPPTHG 209


>gi|239745650 PREDICTED: hypothetical protein XP_002344167 [Homo
           sapiens]
          Length = 484

 Score = 32.7 bits (73), Expect = 1.1
 Identities = 31/94 (32%), Positives = 43/94 (45%), Gaps = 5/94 (5%)

Query: 11  GEAFGAGTWDKVSVSIVGTRGESP-PLPLDNLGKEFTAGAEEDFQVT---LPEDVGRVLL 66
           GE  G G   ++ +   G R E+   + LD LG+E     E   Q     + E + RV L
Sbjct: 117 GEQCGVGARARLGLEKSGPRAEAHLAVQLDVLGEERVDLGERAAQAAGMHVQEVLDRVHL 176

Query: 67  LRVHKAPPVLPLLGPLAPDAWFCRWFQLTPPRGG 100
           + +HK  P+L L  P + DA   R   L PP  G
Sbjct: 177 VVLHKMLPILELPSPSSRDA-LHRGGPLPPPTHG 209


>gi|195972805 myocyte enhancer factor 2A isoform 4 [Homo sapiens]
          Length = 429

 Score = 32.3 bits (72), Expect = 1.5
 Identities = 31/94 (32%), Positives = 39/94 (41%), Gaps = 7/94 (7%)

Query: 219 FRRTPAAEHAFEHWQEDAFFASQFLNGLNPVLIRRCHYLPKNFPVTDAMVASVLGPGTSL 278
           F  +P +E  F    ED+ F   F  G  P L  +   +    PVT     S   PG+SL
Sbjct: 37  FEHSPLSEDRFSKLNEDSDFI--FKRG-PPGLPPQNFSMSVTVPVTSPNALSYTNPGSSL 93

Query: 279 QAELEKGSLFLVDHGILSGIQT----NVINGKPQ 308
            +     S  L D  +LS  QT    NV  G PQ
Sbjct: 94  VSPSLAASSTLTDSSMLSPPQTTLHRNVSPGAPQ 127


>gi|195972803 myocyte enhancer factor 2A isoform 3 [Homo sapiens]
          Length = 437

 Score = 32.3 bits (72), Expect = 1.5
 Identities = 31/94 (32%), Positives = 39/94 (41%), Gaps = 7/94 (7%)

Query: 219 FRRTPAAEHAFEHWQEDAFFASQFLNGLNPVLIRRCHYLPKNFPVTDAMVASVLGPGTSL 278
           F  +P +E  F    ED+ F   F  G  P L  +   +    PVT     S   PG+SL
Sbjct: 37  FEHSPLSEDRFSKLNEDSDFI--FKRG-PPGLPPQNFSMSVTVPVTSPNALSYTNPGSSL 93

Query: 279 QAELEKGSLFLVDHGILSGIQT----NVINGKPQ 308
            +     S  L D  +LS  QT    NV  G PQ
Sbjct: 94  VSPSLAASSTLTDSSMLSPPQTTLHRNVSPGAPQ 127


>gi|195972801 myocyte enhancer factor 2A isoform 2 [Homo sapiens]
          Length = 497

 Score = 32.3 bits (72), Expect = 1.5
 Identities = 31/94 (32%), Positives = 39/94 (41%), Gaps = 7/94 (7%)

Query: 219 FRRTPAAEHAFEHWQEDAFFASQFLNGLNPVLIRRCHYLPKNFPVTDAMVASVLGPGTSL 278
           F  +P +E  F    ED+ F   F  G  P L  +   +    PVT     S   PG+SL
Sbjct: 105 FEHSPLSEDRFSKLNEDSDFI--FKRG-PPGLPPQNFSMSVTVPVTSPNALSYTNPGSSL 161

Query: 279 QAELEKGSLFLVDHGILSGIQT----NVINGKPQ 308
            +     S  L D  +LS  QT    NV  G PQ
Sbjct: 162 VSPSLAASSTLTDSSMLSPPQTTLHRNVSPGAPQ 195


>gi|224458288 lipoxygenase homology domains 1 isoform 2 [Homo
           sapiens]
          Length = 1114

 Score = 31.2 bits (69), Expect = 3.3
 Identities = 28/115 (24%), Positives = 47/115 (40%), Gaps = 20/115 (17%)

Query: 4   FRVRVSTGEAFGAGTWDKVSVSIVGTRGESPPLPLDNLGKEFTAGAEEDFQVTLPE--DV 61
           F V + TG    AGT   V +++ GT+ ++    L +          +  ++   E  D+
Sbjct: 66  FSVTIKTGVKKNAGTDANVFITLFGTQDDTGMTLLKSSKTNSDKFERDSIEIFTVETLDL 125

Query: 62  GRVLLLRV-----HKAPPVLPLLGPLAPDAWFCRWFQL-TPPRGGHLLFPCYQWL 110
           G +  +R+      KAP             WF  W ++  P  G  + FPC +WL
Sbjct: 126 GDLWKVRLGHDNTGKAP------------GWFVDWVEVDAPSLGKCMTFPCGRWL 168


>gi|239755589 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 356

 Score = 30.8 bits (68), Expect = 4.3
 Identities = 14/41 (34%), Positives = 23/41 (56%), Gaps = 4/41 (9%)

Query: 550 SAKHAAVSAGQFDSCAWMP----NLPPSMQLPPPTSKGLAT 586
           S++H+++S G+ D C +      + PP+  LPPP   G  T
Sbjct: 162 SSRHSSISEGEGDRCGFAEPPGGSSPPAPPLPPPPKPGSPT 202


>gi|155969714 nuclear protein,  ataxia-telangiectasia locus [Homo
           sapiens]
          Length = 1427

 Score = 30.4 bits (67), Expect = 5.6
 Identities = 18/67 (26%), Positives = 33/67 (49%), Gaps = 6/67 (8%)

Query: 128 ADHHPVLQQQRQEELQARQEMYQWKAYNPGWPHCLDEKTVEDLELNIKYSTAKNANFYLQ 187
           +++H VL+Q+ QE         Q KA+    P      T +  +++I + +  N N + Q
Sbjct: 402 SNNHDVLRQEDQENFSQISTSIQKKAFKTAVP------TEQKCDIDITFESVPNLNDFNQ 455

Query: 188 AGSAFAE 194
            G++ AE
Sbjct: 456 RGNSNAE 462


>gi|117168250 phospholipase C, epsilon 1 [Homo sapiens]
          Length = 2302

 Score = 30.0 bits (66), Expect = 7.3
 Identities = 17/54 (31%), Positives = 30/54 (55%), Gaps = 2/54 (3%)

Query: 91  WFQLTPPRGGHLLFPCYQWLEGAGTL-VLQEGTAKVSWADHHPVLQQQRQEELQ 143
           W  +   R G LL PC + +E   T+ + Q+G+ ++S A  +P+    R+EE +
Sbjct: 361 WSYIDQKRNGPLL-PCGRVMEPPSTVEIRQDGSQRLSEAQWYPIYNAVRREETE 413


>gi|4557701 keratin 17 [Homo sapiens]
          Length = 432

 Score = 30.0 bits (66), Expect = 7.3
 Identities = 19/66 (28%), Positives = 32/66 (48%)

Query: 126 SWADHHPVLQQQRQEELQARQEMYQWKAYNPGWPHCLDEKTVEDLELNIKYSTAKNANFY 185
           S+ D    L++   E     ++ YQ +A  P   +    +T+E+L+  I  +T  NAN  
Sbjct: 97  SYLDKVRALEEANTELEVKIRDWYQRQAPGPARDYSQYYRTIEELQNKILTATVDNANIL 156

Query: 186 LQAGSA 191
           LQ  +A
Sbjct: 157 LQIDNA 162


>gi|5031653 breast carcinoma amplified sequence 2 [Homo sapiens]
          Length = 225

 Score = 30.0 bits (66), Expect = 7.3
 Identities = 17/58 (29%), Positives = 28/58 (48%), Gaps = 2/58 (3%)

Query: 141 ELQARQEMYQWKAYNPGWPHCLD--EKTVEDLELNIKYSTAKNANFYLQAGSAFAEMK 196
           EL ++     WK YN    H ++  +K ++ L  +I+    +  N  L AGS   EM+
Sbjct: 125 ELMSQHGCNAWKVYNENLVHMIEHAQKELQKLRKHIQDLNWQRKNMQLTAGSKLREME 182


>gi|205360962 polycystin 1 isoform 2 precursor [Homo sapiens]
          Length = 4302

 Score = 29.6 bits (65), Expect = 9.5
 Identities = 18/67 (26%), Positives = 31/67 (46%), Gaps = 1/67 (1%)

Query: 3    EFRVRVSTGEAFGAGTWDKVSVSIVGTRGESPPLPLDNLGKEFTAGAEEDFQVTLPEDVG 62
            ++ + V TG   G+GT   V + + G    S    LD   + F   + + F++  P  +G
Sbjct: 3119 KYEILVKTGWGRGSGTTAHVGIMLYGVDSRSGHRHLDG-DRAFHRNSLDIFRIATPHSLG 3177

Query: 63   RVLLLRV 69
             V  +RV
Sbjct: 3178 SVWKIRV 3184


>gi|205360954 polycystin 1 isoform 1 precursor [Homo sapiens]
          Length = 4303

 Score = 29.6 bits (65), Expect = 9.5
 Identities = 18/67 (26%), Positives = 31/67 (46%), Gaps = 1/67 (1%)

Query: 3    EFRVRVSTGEAFGAGTWDKVSVSIVGTRGESPPLPLDNLGKEFTAGAEEDFQVTLPEDVG 62
            ++ + V TG   G+GT   V + + G    S    LD   + F   + + F++  P  +G
Sbjct: 3119 KYEILVKTGWGRGSGTTAHVGIMLYGVDSRSGHRHLDG-DRAFHRNSLDIFRIATPHSLG 3177

Query: 63   RVLLLRV 69
             V  +RV
Sbjct: 3178 SVWKIRV 3184


>gi|194248077 Kruppel-like factor 4 (gut) [Homo sapiens]
          Length = 479

 Score = 29.6 bits (65), Expect = 9.5
 Identities = 14/27 (51%), Positives = 14/27 (51%)

Query: 320 SPGCGPLLPLAIQLSQTPGPNSPIFLP 346
           S  C P LPL       PGPN P FLP
Sbjct: 327 SRDCHPALPLPPGFHPHPGPNYPSFLP 353


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.320    0.137    0.432 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 28,908,933
Number of Sequences: 37866
Number of extensions: 1411166
Number of successful extensions: 3663
Number of sequences better than 10.0: 26
Number of HSP's better than 10.0 without gapping: 11
Number of HSP's successfully gapped in prelim test: 15
Number of HSP's that attempted gapping in prelim test: 3609
Number of HSP's gapped (non-prelim): 46
length of query: 676
length of database: 18,247,518
effective HSP length: 109
effective length of query: 567
effective length of database: 14,120,124
effective search space: 8006110308
effective search space used: 8006110308
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 65 (29.6 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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