Search of human proteins with 83641870

Search of human proteins with 83641870

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|83641870 nucleophosmin 1 isoform 3 [Homo sapiens]
         (259 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|83641870 nucleophosmin 1 isoform 3 [Homo sapiens]                  519   e-148
gi|10835063 nucleophosmin 1 isoform 1 [Homo sapiens]                  514   e-146
gi|40353734 nucleophosmin 1 isoform 2 [Homo sapiens]                  442   e-124
gi|169161779 PREDICTED: similar to nucleophosmin 1 [Homo sapiens]     355   3e-98
gi|169161624 PREDICTED: similar to nucleophosmin 1 [Homo sapiens]     355   3e-98
gi|169162829 PREDICTED: similar to nucleophosmin 1 [Homo sapiens]     355   3e-98
gi|6857818 nucleophosmin/nucleoplasmin 3 [Homo sapiens]               106   2e-23
gi|33391150 nucleoplasmin 2 [Homo sapiens]                             92   4e-19
gi|55956788 nucleolin [Homo sapiens]                                   73   3e-13
gi|94681063 bromodomain adjacent to zinc finger domain, 2B [Homo...    61   8e-10
gi|115529449 upstream binding transcription factor, RNA polymera...    57   2e-08
gi|115529451 upstream binding transcription factor, RNA polymera...    57   2e-08
gi|7657671 upstream binding transcription factor, RNA polymerase...    57   2e-08
gi|24497618 ATPase family, AAA domain containing 2 [Homo sapiens]      55   6e-08
gi|153791492 eukaryotic translation initiation factor 3, subunit...    52   4e-07
gi|83700233 eukaryotic translation initiation factor 3, subunit ...    52   4e-07
gi|4503525 eukaryotic translation initiation factor 3, subunit C...    52   4e-07
gi|166795264 AE binding protein 2 isoform b [Homo sapiens]             52   5e-07
gi|166795262 AE binding protein 2 isoform a [Homo sapiens]             52   5e-07
gi|42740903 MTERF domain containing 2 [Homo sapiens]                   51   9e-07
gi|148596949 nucleolar and coiled-body phosphoprotein 1 [Homo sa...    51   9e-07
gi|119709834 castor homolog 1, zinc finger isoform a [Homo sapiens]    50   2e-06
gi|210032580 SET domain containing 1B [Homo sapiens]                   49   4e-06
gi|239744307 PREDICTED: similar to hCG1991922 [Homo sapiens]           49   6e-06
gi|17975763 myelin transcription factor 1 [Homo sapiens]               49   6e-06
gi|156104891 general transcription factor IIF, polypeptide 1, 74...    49   6e-06
gi|187960109 RNA binding motif protein 28 [Homo sapiens]               49   6e-06
gi|21735415 centromere protein B [Homo sapiens]                        48   7e-06
gi|18093112 ABT1-associated protein [Homo sapiens]                     48   7e-06
gi|51477718 TATA box binding protein-associated factor, RNA poly...    48   1e-05

>gi|83641870 nucleophosmin 1 isoform 3 [Homo sapiens]
          Length = 259

 Score =  519 bits (1337), Expect = e-148
 Identities = 259/259 (100%), Positives = 259/259 (100%)

Query: 1   MEDSMDMDMSPLRPQNYLFGCELKADKDYHFKVDNDENEHQLSLRTVSLGAGAKDELHIV 60
           MEDSMDMDMSPLRPQNYLFGCELKADKDYHFKVDNDENEHQLSLRTVSLGAGAKDELHIV
Sbjct: 1   MEDSMDMDMSPLRPQNYLFGCELKADKDYHFKVDNDENEHQLSLRTVSLGAGAKDELHIV 60

Query: 61  EAEAMNYEGSPIKVTLATLKMSVQPTVSLGGFEITPPVVLRLKCGSGPVHISGQHLVAVE 120
           EAEAMNYEGSPIKVTLATLKMSVQPTVSLGGFEITPPVVLRLKCGSGPVHISGQHLVAVE
Sbjct: 61  EAEAMNYEGSPIKVTLATLKMSVQPTVSLGGFEITPPVVLRLKCGSGPVHISGQHLVAVE 120

Query: 121 EDAESEDEEEEDVKLLSISGKRSAPGGGSKVPQKKVKLAADEDDDDDDEEDDDEDDDDDD 180
           EDAESEDEEEEDVKLLSISGKRSAPGGGSKVPQKKVKLAADEDDDDDDEEDDDEDDDDDD
Sbjct: 121 EDAESEDEEEEDVKLLSISGKRSAPGGGSKVPQKKVKLAADEDDDDDDEEDDDEDDDDDD 180

Query: 181 FDDEEAEEKAPVKKSIRDTPAKNAQKSNQNGKDSKPSSTPRSKGQESFKKQEKTPKTPKG 240
           FDDEEAEEKAPVKKSIRDTPAKNAQKSNQNGKDSKPSSTPRSKGQESFKKQEKTPKTPKG
Sbjct: 181 FDDEEAEEKAPVKKSIRDTPAKNAQKSNQNGKDSKPSSTPRSKGQESFKKQEKTPKTPKG 240

Query: 241 PSSVEDIKAKMQASIEKAH 259
           PSSVEDIKAKMQASIEKAH
Sbjct: 241 PSSVEDIKAKMQASIEKAH 259


>gi|10835063 nucleophosmin 1 isoform 1 [Homo sapiens]
          Length = 294

 Score =  514 bits (1325), Expect = e-146
 Identities = 257/257 (100%), Positives = 257/257 (100%)

Query: 1   MEDSMDMDMSPLRPQNYLFGCELKADKDYHFKVDNDENEHQLSLRTVSLGAGAKDELHIV 60
           MEDSMDMDMSPLRPQNYLFGCELKADKDYHFKVDNDENEHQLSLRTVSLGAGAKDELHIV
Sbjct: 1   MEDSMDMDMSPLRPQNYLFGCELKADKDYHFKVDNDENEHQLSLRTVSLGAGAKDELHIV 60

Query: 61  EAEAMNYEGSPIKVTLATLKMSVQPTVSLGGFEITPPVVLRLKCGSGPVHISGQHLVAVE 120
           EAEAMNYEGSPIKVTLATLKMSVQPTVSLGGFEITPPVVLRLKCGSGPVHISGQHLVAVE
Sbjct: 61  EAEAMNYEGSPIKVTLATLKMSVQPTVSLGGFEITPPVVLRLKCGSGPVHISGQHLVAVE 120

Query: 121 EDAESEDEEEEDVKLLSISGKRSAPGGGSKVPQKKVKLAADEDDDDDDEEDDDEDDDDDD 180
           EDAESEDEEEEDVKLLSISGKRSAPGGGSKVPQKKVKLAADEDDDDDDEEDDDEDDDDDD
Sbjct: 121 EDAESEDEEEEDVKLLSISGKRSAPGGGSKVPQKKVKLAADEDDDDDDEEDDDEDDDDDD 180

Query: 181 FDDEEAEEKAPVKKSIRDTPAKNAQKSNQNGKDSKPSSTPRSKGQESFKKQEKTPKTPKG 240
           FDDEEAEEKAPVKKSIRDTPAKNAQKSNQNGKDSKPSSTPRSKGQESFKKQEKTPKTPKG
Sbjct: 181 FDDEEAEEKAPVKKSIRDTPAKNAQKSNQNGKDSKPSSTPRSKGQESFKKQEKTPKTPKG 240

Query: 241 PSSVEDIKAKMQASIEK 257
           PSSVEDIKAKMQASIEK
Sbjct: 241 PSSVEDIKAKMQASIEK 257


>gi|40353734 nucleophosmin 1 isoform 2 [Homo sapiens]
          Length = 265

 Score =  442 bits (1137), Expect = e-124
 Identities = 228/257 (88%), Positives = 228/257 (88%), Gaps = 29/257 (11%)

Query: 1   MEDSMDMDMSPLRPQNYLFGCELKADKDYHFKVDNDENEHQLSLRTVSLGAGAKDELHIV 60
           MEDSMDMDMSPLRPQNYLFGCELKADKDYHFKVDNDENEHQLSLRTVSLGAGAKDELHIV
Sbjct: 1   MEDSMDMDMSPLRPQNYLFGCELKADKDYHFKVDNDENEHQLSLRTVSLGAGAKDELHIV 60

Query: 61  EAEAMNYEGSPIKVTLATLKMSVQPTVSLGGFEITPPVVLRLKCGSGPVHISGQHLVAVE 120
           EAEAMNYEGSPIKVTLATLKMSVQPTVSLGGFEITPPVVLRLKCGSGPVHISGQHLVAVE
Sbjct: 61  EAEAMNYEGSPIKVTLATLKMSVQPTVSLGGFEITPPVVLRLKCGSGPVHISGQHLVAVE 120

Query: 121 EDAESEDEEEEDVKLLSISGKRSAPGGGSKVPQKKVKLAADEDDDDDDEEDDDEDDDDDD 180
           EDAESEDEEEEDVKLLSISGKRSAPGGGSKVPQKKVKLAADEDDDDDDEEDDDEDDDDDD
Sbjct: 121 EDAESEDEEEEDVKLLSISGKRSAPGGGSKVPQKKVKLAADEDDDDDDEEDDDEDDDDDD 180

Query: 181 FDDEEAEEKAPVKKSIRDTPAKNAQKSNQNGKDSKPSSTPRSKGQESFKKQEKTPKTPKG 240
           FDDEEAEEKAPVK                             KGQESFKKQEKTPKTPKG
Sbjct: 181 FDDEEAEEKAPVK-----------------------------KGQESFKKQEKTPKTPKG 211

Query: 241 PSSVEDIKAKMQASIEK 257
           PSSVEDIKAKMQASIEK
Sbjct: 212 PSSVEDIKAKMQASIEK 228


>gi|169161779 PREDICTED: similar to nucleophosmin 1 [Homo sapiens]
          Length = 186

 Score =  355 bits (910), Expect = 3e-98
 Identities = 179/192 (93%), Positives = 180/192 (93%), Gaps = 6/192 (3%)

Query: 5   MDMDMSPLRPQNYLFGCELKADKDYHFKVDNDENEHQLSLRTVSLGAGAKDELHIVEAEA 64
           MDMDMSPLRPQNYLFGCELKADKD HFKVDNDENEHQLSLRTVSLGAG KDELHIVEAEA
Sbjct: 1   MDMDMSPLRPQNYLFGCELKADKDDHFKVDNDENEHQLSLRTVSLGAGTKDELHIVEAEA 60

Query: 65  MNYEGSPIKVTLATLKMSVQPTVSLGGFEITPPVVLRLKCGSGPVHISGQHLVAVEEDAE 124
           MNY+GSPIKVTLATLKMS QPTVSLGGFEITPPVVLR KCGSGPVHISGQHLVAVEEDAE
Sbjct: 61  MNYKGSPIKVTLATLKMSAQPTVSLGGFEITPPVVLRFKCGSGPVHISGQHLVAVEEDAE 120

Query: 125 SEDEEEEDVKLLSISGKRSAPGGGSKVPQKKVKLAADEDDDDDDEEDDDEDDDDDDFDDE 184
           SEDEEEEDVKLLSISGKRSAPGGGSKVPQKKVKLA DEDDDDDD      DDDDDDFDDE
Sbjct: 121 SEDEEEEDVKLLSISGKRSAPGGGSKVPQKKVKLAVDEDDDDDD------DDDDDDFDDE 174

Query: 185 EAEEKAPVKKSI 196
           EAEEK PVKKSI
Sbjct: 175 EAEEKVPVKKSI 186


>gi|169161624 PREDICTED: similar to nucleophosmin 1 [Homo sapiens]
          Length = 186

 Score =  355 bits (910), Expect = 3e-98
 Identities = 179/192 (93%), Positives = 180/192 (93%), Gaps = 6/192 (3%)

Query: 5   MDMDMSPLRPQNYLFGCELKADKDYHFKVDNDENEHQLSLRTVSLGAGAKDELHIVEAEA 64
           MDMDMSPLRPQNYLFGCELKADKD HFKVDNDENEHQLSLRTVSLGAG KDELHIVEAEA
Sbjct: 1   MDMDMSPLRPQNYLFGCELKADKDDHFKVDNDENEHQLSLRTVSLGAGTKDELHIVEAEA 60

Query: 65  MNYEGSPIKVTLATLKMSVQPTVSLGGFEITPPVVLRLKCGSGPVHISGQHLVAVEEDAE 124
           MNY+GSPIKVTLATLKMS QPTVSLGGFEITPPVVLR KCGSGPVHISGQHLVAVEEDAE
Sbjct: 61  MNYKGSPIKVTLATLKMSAQPTVSLGGFEITPPVVLRFKCGSGPVHISGQHLVAVEEDAE 120

Query: 125 SEDEEEEDVKLLSISGKRSAPGGGSKVPQKKVKLAADEDDDDDDEEDDDEDDDDDDFDDE 184
           SEDEEEEDVKLLSISGKRSAPGGGSKVPQKKVKLA DEDDDDDD      DDDDDDFDDE
Sbjct: 121 SEDEEEEDVKLLSISGKRSAPGGGSKVPQKKVKLAVDEDDDDDD------DDDDDDFDDE 174

Query: 185 EAEEKAPVKKSI 196
           EAEEK PVKKSI
Sbjct: 175 EAEEKVPVKKSI 186


>gi|169162829 PREDICTED: similar to nucleophosmin 1 [Homo sapiens]
          Length = 186

 Score =  355 bits (910), Expect = 3e-98
 Identities = 179/192 (93%), Positives = 180/192 (93%), Gaps = 6/192 (3%)

Query: 5   MDMDMSPLRPQNYLFGCELKADKDYHFKVDNDENEHQLSLRTVSLGAGAKDELHIVEAEA 64
           MDMDMSPLRPQNYLFGCELKADKD HFKVDNDENEHQLSLRTVSLGAG KDELHIVEAEA
Sbjct: 1   MDMDMSPLRPQNYLFGCELKADKDDHFKVDNDENEHQLSLRTVSLGAGTKDELHIVEAEA 60

Query: 65  MNYEGSPIKVTLATLKMSVQPTVSLGGFEITPPVVLRLKCGSGPVHISGQHLVAVEEDAE 124
           MNY+GSPIKVTLATLKMS QPTVSLGGFEITPPVVLR KCGSGPVHISGQHLVAVEEDAE
Sbjct: 61  MNYKGSPIKVTLATLKMSAQPTVSLGGFEITPPVVLRFKCGSGPVHISGQHLVAVEEDAE 120

Query: 125 SEDEEEEDVKLLSISGKRSAPGGGSKVPQKKVKLAADEDDDDDDEEDDDEDDDDDDFDDE 184
           SEDEEEEDVKLLSISGKRSAPGGGSKVPQKKVKLA DEDDDDDD      DDDDDDFDDE
Sbjct: 121 SEDEEEEDVKLLSISGKRSAPGGGSKVPQKKVKLAVDEDDDDDD------DDDDDDFDDE 174

Query: 185 EAEEKAPVKKSI 196
           EAEEK PVKKSI
Sbjct: 175 EAEEKVPVKKSI 186


>gi|6857818 nucleophosmin/nucleoplasmin 3 [Homo sapiens]
          Length = 178

 Score =  106 bits (265), Expect = 2e-23
 Identities = 58/139 (41%), Positives = 84/139 (60%), Gaps = 10/139 (7%)

Query: 10  SPLRPQNYLFGCELKAD-KDYHFKVDN-DENEHQLSLRTVSLGAGAKDELHIVEAEAMNY 67
           +P+   ++ FGCEL    + + FKV+  D+ EH L+L  + L  GAKDE ++VE  A N+
Sbjct: 30  APVTMDSFFFGCELSGHTRSFTFKVEEEDDAEHVLALTMLCLTEGAKDECNVVEVVARNH 89

Query: 68  EGSPIKVTLATLKMSVQPTVSLGGFEITPPVVLRLKCGSGPVHISGQHLVAV-------- 119
           +   I V +A LK+S QP +SL  F++ PPV  RLK GSGPV I+G+H +          
Sbjct: 90  DHQEIAVPVANLKLSCQPMLSLDDFQLQPPVTFRLKSGSGPVRITGRHQIVTMSNDVSEE 149

Query: 120 EEDAESEDEEEEDVKLLSI 138
           E + E ED +EE+V+L  I
Sbjct: 150 ESEEEEEDSDEEEVELCPI 168


>gi|33391150 nucleoplasmin 2 [Homo sapiens]
          Length = 214

 Score = 92.0 bits (227), Expect = 4e-19
 Identities = 68/228 (29%), Positives = 109/228 (47%), Gaps = 39/228 (17%)

Query: 18  LFGCELKADK-DYHFKVDNDENEH-QLSLRTVSLGAGAKDELHIVEA-EAMNYEGSPIK- 73
           L+GCEL  ++  + F+   +  +  +L L T+ LG  AK+E+H VE     N E   ++ 
Sbjct: 18  LWGCELSQERRTWTFRPQLEGKQSCRLLLHTICLGEKAKEEMHRVEILPPANQEDKKMQP 77

Query: 74  VTLATLKMSVQPTVSLGGFEITPPVVLRLKCGSGPVHISGQHLVAVEEDAESEDEEEEDV 133
           VT+A+L+ SV P VS+ G +++PPV  +L+ GSGPV +SGQ      +    E+EEEE  
Sbjct: 78  VTIASLQASVLPMVSMVGVQLSPPVTFQLRAGSGPVFLSGQERYEASDLTWEEEEEEE-- 135

Query: 134 KLLSISGKRSAPGGGSKVPQKKVKLAADEDDDDDDEEDDDEDDDDDDFDDEEAEEKAPVK 193
                                             +EE+++E+DD+D+  D   EE++PVK
Sbjct: 136 ---------------------------------GEEEEEEEEDDEDEDADISLEEQSPVK 162

Query: 194 KSIRDTPAKNAQKSNQNGKDSKPSSTPRSKGQESFKKQEKTPKTPKGP 241
           +  R  P K A  + +   + +      S   +S  K+ K     K P
Sbjct: 163 QVKRLVPQKQASVAKKKKLEKEEEEIRASVRDKSPVKKAKATARAKKP 210


>gi|55956788 nucleolin [Homo sapiens]
          Length = 710

 Score = 72.8 bits (177), Expect = 3e-13
 Identities = 45/141 (31%), Positives = 75/141 (53%), Gaps = 5/141 (3%)

Query: 120 EEDAESEDEEEEDVKLLSISGKRSA---PGGGSKVPQKKVKLAADEDDDDDDEEDDDEDD 176
           ++D E +D EEE ++     GK++A   P     V + + +   DED+DDDD+EDD++DD
Sbjct: 198 DDDDEEDDSEEEAMETTPAKGKKAAKVVPVKAKNVAEDEDEEEDDEDEDDDDDEDDEDDD 257

Query: 177 DDDDFDDEEAEEKAPVKKSIRDTPAKNA-QKSNQNGKDSKPSSTPRSKGQESFKKQEKTP 235
           D+DD ++EE EE+ PVK++      + A QK+    K  K   T  +     F       
Sbjct: 258 DEDDEEEEEEEEEEPVKEAPGKRKKEMAKQKAAPEAKKQKVEGTEPTTAFNLFVGNLNFN 317

Query: 236 KT-PKGPSSVEDIKAKMQASI 255
           K+ P+  + + D+ AK   ++
Sbjct: 318 KSAPELKTGISDVFAKNDLAV 338



 Score = 66.6 bits (161), Expect = 2e-11
 Identities = 37/149 (24%), Positives = 73/149 (48%), Gaps = 25/149 (16%)

Query: 120 EEDAESEDEEEEDVKLLSISGKRSAPGGGSKVPQKKVKLAADEDDDDDDEEDDDEDDDDD 179
           EED E EDE+E++++  ++    +AP             A++++DD+DDE+D+D+DDD++
Sbjct: 157 EEDDEDEDEDEDEIEPAAMKAAAAAP-------------ASEDEDDEDDEDDEDDDDDEE 203

Query: 180 DFDDEEAEEKAPVK------------KSIRDTPAKNAQKSNQNGKDSKPSSTPRSKGQES 227
           D  +EEA E  P K            K++ +   +     +++  D +       +  E 
Sbjct: 204 DDSEEEAMETTPAKGKKAAKVVPVKAKNVAEDEDEEEDDEDEDDDDDEDDEDDDDEDDEE 263

Query: 228 FKKQEKTPKTPKGPSSVEDIKAKMQASIE 256
            +++E+     + P   +   AK +A+ E
Sbjct: 264 EEEEEEEEPVKEAPGKRKKEMAKQKAAPE 292



 Score = 51.2 bits (121), Expect = 9e-07
 Identities = 38/137 (27%), Positives = 59/137 (43%), Gaps = 16/137 (11%)

Query: 134 KLLSISGKRSAPGG----------GSKVPQKKVKLAADEDDDDDDEEDDD---EDDDDDD 180
           K ++  GK+ A  G          G+ +P K  K   +   +D DEE+DD   ED++DD+
Sbjct: 102 KAVTTPGKKGATPGKALVATPGKKGAAIPAKGAKNGKNAKKEDSDEEEDDDSEEDEEDDE 161

Query: 181 FDDEEAEEKAP-VKKSIRDTPAKNAQKSNQNGKDSKPSSTPRSKGQESFKKQEKTPKTPK 239
            +DE+ +E  P   K+    PA   +    +  D           +E  +  E TP   K
Sbjct: 162 DEDEDEDEIEPAAMKAAAAAPASEDEDDEDDEDDEDDDDDEEDDSEE--EAMETTPAKGK 219

Query: 240 GPSSVEDIKAKMQASIE 256
             + V  +KAK  A  E
Sbjct: 220 KAAKVVPVKAKNVAEDE 236



 Score = 30.4 bits (67), Expect = 1.6
 Identities = 27/120 (22%), Positives = 45/120 (37%), Gaps = 25/120 (20%)

Query: 141 KRSAPGGGSKVPQKKVKLAADEDDDDDDEEDDDEDDDDDDFDDEEAEEK----------- 189
           K +  G     P+K      + ++D +DEE  ++++DD   ++    +K           
Sbjct: 3   KLAKAGKNQGDPKKMAPPPKEVEEDSEDEEMSEDEEDDSSGEEVVIPQKKGKKAAATSAK 62

Query: 190 ----APVKKSIRDTPAKN----------AQKSNQNGKDSKPSSTPRSKGQESFKKQEKTP 235
               +P KK    TPAK           A  + +    +K  +TP  KG    K    TP
Sbjct: 63  KVVVSPTKKVAVATPAKKAAVTPGKKAAATPAKKTVTPAKAVTTPGKKGATPGKALVATP 122


>gi|94681063 bromodomain adjacent to zinc finger domain, 2B [Homo
           sapiens]
          Length = 2168

 Score = 61.2 bits (147), Expect = 8e-10
 Identities = 32/97 (32%), Positives = 53/97 (54%), Gaps = 6/97 (6%)

Query: 146 GGGSKVPQKKVKLAADEDDDDDDEEDDDEDDDDDDFDDEEAEEKAPVKKSIRDTPAKNAQ 205
           G  S +P  K    ++ED+++DDEE+D+EDD+DD+ DD ++E  +    S  DT     +
Sbjct: 593 GTDSDIPSSKDSEDSNEDEEEDDEEEDEEDDEDDESDDSQSESDS---NSESDTEGSEEE 649

Query: 206 KSNQNGKDSKPSSTPRSKGQESFKKQEKTPKTPKGPS 242
             +   +D   S T   +G+++  K  KT  + K PS
Sbjct: 650 DDDDKDQDESDSDT---EGEKTSMKLNKTTSSVKSPS 683



 Score = 47.8 bits (112), Expect = 1e-05
 Identities = 34/102 (33%), Positives = 47/102 (46%), Gaps = 17/102 (16%)

Query: 139  SGKRSAPGG----------GSKVP-QKKVKLAADEDDDDDDEEDDDEDDDDDDFDDEEAE 187
            +GKR   GG          G+  P +K+ +   D D DDDD++D D+  D+DD D+E+ E
Sbjct: 1263 TGKRDTSGGIDLGEEQHPLGTPTPGRKRRRKGGDSDYDDDDDDDSDDQGDEDDEDEEDKE 1322

Query: 188  EKAPVKKSI------RDTPAKNAQKSNQNGKDSKPSSTPRSK 223
            +K   K  I       D  A   +   Q  K SK  S  R K
Sbjct: 1323 DKKGKKTDICEDEDEGDQAASVEELEKQIEKLSKQQSQYRRK 1364



 Score = 42.0 bits (97), Expect = 5e-04
 Identities = 25/112 (22%), Positives = 52/112 (46%), Gaps = 9/112 (8%)

Query: 134 KLLSISGKRSAPGGGSKVPQKKVKLAADEDDDDDDEEDDDEDDDDDDFDDEEAEEKAPVK 193
           K +  S    +  G S     +   ++D DD ++DEE++D+  ++ + DD ++E +A  K
Sbjct: 237 KAMESSSNSDSDSGTSSDTSSEGISSSDSDDLEEDEEEEDQSIEESEDDDSDSESEAQHK 296

Query: 194 KSIR------DTPAKNAQKSNQNGKDSK---PSSTPRSKGQESFKKQEKTPK 236
            + +        P  + QK+ +  ++ +   P          SF+ Q+K P+
Sbjct: 297 SNNQVLLHGISDPKADGQKATEKAQEKRIHQPLPLASESQTHSFQSQQKQPQ 348



 Score = 38.1 bits (87), Expect = 0.008
 Identities = 25/88 (28%), Positives = 37/88 (42%), Gaps = 14/88 (15%)

Query: 120 EEDAESEDEEEEDVKLLSISGKRSAPGGGSKVPQKKVKLAADEDDDDDDEEDDDEDDDDD 179
           EED E EDEE+++      S   S                  E D +  EE+DD+D D D
Sbjct: 612 EEDDEEEDEEDDEDDESDDSQSESDSNS--------------ESDTEGSEEEDDDDKDQD 657

Query: 180 DFDDEEAEEKAPVKKSIRDTPAKNAQKS 207
           + D +   EK  +K +   +  K+   S
Sbjct: 658 ESDSDTEGEKTSMKLNKTTSSVKSPSMS 685



 Score = 36.2 bits (82), Expect = 0.029
 Identities = 28/110 (25%), Positives = 52/110 (47%), Gaps = 6/110 (5%)

Query: 128  EEEEDVKLLSISGKRSAPGGGSKVPQKKVKLAADEDDDDDDEEDDDED----DDDDDFDD 183
            EE+  +   +   KR   GG S         + D+ D+DD++E+D ED      D   D+
Sbjct: 1276 EEQHPLGTPTPGRKRRRKGGDSDYDDDDDDDSDDQGDEDDEDEEDKEDKKGKKTDICEDE 1335

Query: 184  EEAEEKAPVKKSIRDTPAKNAQKSNQNGKDSKPSSTPRSK--GQESFKKQ 231
            +E ++ A V++  +     + Q+S    K    S + RS   GQ+ ++++
Sbjct: 1336 DEGDQAASVEELEKQIEKLSKQQSQYRRKLFDASHSLRSVMFGQDRYRRR 1385


>gi|115529449 upstream binding transcription factor, RNA polymerase
           I isoform b [Homo sapiens]
          Length = 727

 Score = 56.6 bits (135), Expect = 2e-08
 Identities = 30/80 (37%), Positives = 49/80 (61%), Gaps = 5/80 (6%)

Query: 120 EEDAESEDEEEEDVKLLSISGKRSAPGGGSKVPQKKVKLAADEDDDDDDEEDDDEDDDDD 179
           +ED E EDEEEED +    +G  S  GG S     + + + D D++++D+ED+D+D+DDD
Sbjct: 647 DEDDEDEDEEEEDDE----NGDSSEDGGDSSESSSEDE-SEDGDENEEDDEDEDDDEDDD 701

Query: 180 DFDDEEAEEKAPVKKSIRDT 199
           + +D E+E  +    S  D+
Sbjct: 702 EDEDNESEGSSSSSSSSGDS 721



 Score = 45.8 bits (107), Expect = 4e-05
 Identities = 44/205 (21%), Positives = 85/205 (41%), Gaps = 20/205 (9%)

Query: 62  AEAMNYEGSPIKVTLATLKMSVQPTVSLGGFEITPPVVLRLKCGSGPVHISG---QHLVA 118
           ++ M ++G P K  +   +   Q  +S G     P     ++ GS    IS    +H   
Sbjct: 521 SKKMKFQGEPKKPPMNGYQKFSQELLSNGELNHLPLKERMVEIGSRWQRISQSQKEHYKK 580

Query: 119 VEEDAESEDEEEED--VKLLS----------ISGKRSAPG---GGSKVPQKKVKLAADED 163
           + E+ + + +   D  VK LS          IS KR +     G +    +    +  E 
Sbjct: 581 LAEEQQKQYKVHLDLWVKSLSPQDRAAYKEYISNKRKSMTKLRGPNPKSSRTTLQSKSES 640

Query: 164 DDDDDEEDDDEDDDDDDFDDEEAEEKAPVKKSIRDTPAKNAQKSNQNGKDSKPSSTPRSK 223
           ++DD+E++DDED+D+++ DDE  +       S   +    ++  ++N +D +        
Sbjct: 641 EEDDEEDEDDEDEDEEEEDDENGDSSEDGGDSSESSSEDESEDGDENEEDDEDEDDDEDD 700

Query: 224 GQESFKKQE--KTPKTPKGPSSVED 246
            ++   + E   +  +  G SS  D
Sbjct: 701 DEDEDNESEGSSSSSSSSGDSSDSD 725


>gi|115529451 upstream binding transcription factor, RNA polymerase
           I isoform b [Homo sapiens]
          Length = 727

 Score = 56.6 bits (135), Expect = 2e-08
 Identities = 30/80 (37%), Positives = 49/80 (61%), Gaps = 5/80 (6%)

Query: 120 EEDAESEDEEEEDVKLLSISGKRSAPGGGSKVPQKKVKLAADEDDDDDDEEDDDEDDDDD 179
           +ED E EDEEEED +    +G  S  GG S     + + + D D++++D+ED+D+D+DDD
Sbjct: 647 DEDDEDEDEEEEDDE----NGDSSEDGGDSSESSSEDE-SEDGDENEEDDEDEDDDEDDD 701

Query: 180 DFDDEEAEEKAPVKKSIRDT 199
           + +D E+E  +    S  D+
Sbjct: 702 EDEDNESEGSSSSSSSSGDS 721



 Score = 45.8 bits (107), Expect = 4e-05
 Identities = 44/205 (21%), Positives = 85/205 (41%), Gaps = 20/205 (9%)

Query: 62  AEAMNYEGSPIKVTLATLKMSVQPTVSLGGFEITPPVVLRLKCGSGPVHISG---QHLVA 118
           ++ M ++G P K  +   +   Q  +S G     P     ++ GS    IS    +H   
Sbjct: 521 SKKMKFQGEPKKPPMNGYQKFSQELLSNGELNHLPLKERMVEIGSRWQRISQSQKEHYKK 580

Query: 119 VEEDAESEDEEEED--VKLLS----------ISGKRSAPG---GGSKVPQKKVKLAADED 163
           + E+ + + +   D  VK LS          IS KR +     G +    +    +  E 
Sbjct: 581 LAEEQQKQYKVHLDLWVKSLSPQDRAAYKEYISNKRKSMTKLRGPNPKSSRTTLQSKSES 640

Query: 164 DDDDDEEDDDEDDDDDDFDDEEAEEKAPVKKSIRDTPAKNAQKSNQNGKDSKPSSTPRSK 223
           ++DD+E++DDED+D+++ DDE  +       S   +    ++  ++N +D +        
Sbjct: 641 EEDDEEDEDDEDEDEEEEDDENGDSSEDGGDSSESSSEDESEDGDENEEDDEDEDDDEDD 700

Query: 224 GQESFKKQE--KTPKTPKGPSSVED 246
            ++   + E   +  +  G SS  D
Sbjct: 701 DEDEDNESEGSSSSSSSSGDSSDSD 725


>gi|7657671 upstream binding transcription factor, RNA polymerase I
           isoform a [Homo sapiens]
          Length = 764

 Score = 56.6 bits (135), Expect = 2e-08
 Identities = 30/80 (37%), Positives = 49/80 (61%), Gaps = 5/80 (6%)

Query: 120 EEDAESEDEEEEDVKLLSISGKRSAPGGGSKVPQKKVKLAADEDDDDDDEEDDDEDDDDD 179
           +ED E EDEEEED +    +G  S  GG S     + + + D D++++D+ED+D+D+DDD
Sbjct: 684 DEDDEDEDEEEEDDE----NGDSSEDGGDSSESSSEDE-SEDGDENEEDDEDEDDDEDDD 738

Query: 180 DFDDEEAEEKAPVKKSIRDT 199
           + +D E+E  +    S  D+
Sbjct: 739 EDEDNESEGSSSSSSSSGDS 758



 Score = 45.8 bits (107), Expect = 4e-05
 Identities = 44/205 (21%), Positives = 85/205 (41%), Gaps = 20/205 (9%)

Query: 62  AEAMNYEGSPIKVTLATLKMSVQPTVSLGGFEITPPVVLRLKCGSGPVHISG---QHLVA 118
           ++ M ++G P K  +   +   Q  +S G     P     ++ GS    IS    +H   
Sbjct: 558 SKKMKFQGEPKKPPMNGYQKFSQELLSNGELNHLPLKERMVEIGSRWQRISQSQKEHYKK 617

Query: 119 VEEDAESEDEEEED--VKLLS----------ISGKRSAPG---GGSKVPQKKVKLAADED 163
           + E+ + + +   D  VK LS          IS KR +     G +    +    +  E 
Sbjct: 618 LAEEQQKQYKVHLDLWVKSLSPQDRAAYKEYISNKRKSMTKLRGPNPKSSRTTLQSKSES 677

Query: 164 DDDDDEEDDDEDDDDDDFDDEEAEEKAPVKKSIRDTPAKNAQKSNQNGKDSKPSSTPRSK 223
           ++DD+E++DDED+D+++ DDE  +       S   +    ++  ++N +D +        
Sbjct: 678 EEDDEEDEDDEDEDEEEEDDENGDSSEDGGDSSESSSEDESEDGDENEEDDEDEDDDEDD 737

Query: 224 GQESFKKQE--KTPKTPKGPSSVED 246
            ++   + E   +  +  G SS  D
Sbjct: 738 DEDEDNESEGSSSSSSSSGDSSDSD 762


>gi|24497618 ATPase family, AAA domain containing 2 [Homo sapiens]
          Length = 1390

 Score = 55.1 bits (131), Expect = 6e-08
 Identities = 36/126 (28%), Positives = 57/126 (45%), Gaps = 28/126 (22%)

Query: 118 AVEEDAESEDEEEEDVKLLSISGKRSAPGGGSKVPQKKVKLAADEDDDDDDEEDDDEDDD 177
           +VE   E ED+E ED       G+                   D++DDDDD++DDD+DDD
Sbjct: 241 SVESSEEGEDQEHED------DGEDE-----------------DDEDDDDDDDDDDDDDD 277

Query: 178 DDDFDDEEAEEKAPVKKSIRDTPA-----KNAQKSNQNGKDSKPSSTPRSKGQESFKKQE 232
           +DD D+E+ EE+   +  +R   A        +K     K +   S P S  +  ++   
Sbjct: 278 EDDEDEEDGEEENQKRYYLRQRKATVYYQAPLEKPRHQRKPNIFYSGPASPARPRYRLSS 337

Query: 233 KTPKTP 238
             P++P
Sbjct: 338 AGPRSP 343



 Score = 31.6 bits (70), Expect = 0.72
 Identities = 13/75 (17%), Positives = 36/75 (48%)

Query: 114 QHLVAVEEDAESEDEEEEDVKLLSISGKRSAPGGGSKVPQKKVKLAADEDDDDDDEEDDD 173
           Q +  +E+     + EE ++ + +   ++       +    +       ++ +D E +DD
Sbjct: 197 QRMRELEDLGVFNETEESNLNMYTRGKQKDIQRTDEETTDNQEGSVESSEEGEDQEHEDD 256

Query: 174 EDDDDDDFDDEEAEE 188
            +D+DD+ DD++ ++
Sbjct: 257 GEDEDDEDDDDDDDD 271


>gi|153791492 eukaryotic translation initiation factor 3, subunit
           C-like [Homo sapiens]
          Length = 914

 Score = 52.4 bits (124), Expect = 4e-07
 Identities = 35/123 (28%), Positives = 60/123 (48%), Gaps = 12/123 (9%)

Query: 120 EEDAES---EDEEEEDVKLLSISGKRS-APGGGSKVPQKKVKLAADEDDDDDDEEDDDED 175
           EED+E    EDE+E+ V   +   K+S AP G S+   K +K   DED+D +D EDD++ 
Sbjct: 175 EEDSEGSSDEDEDEDGVSAATFLKKKSEAPSGESR---KFLKKMDDEDEDSEDSEDDEDW 231

Query: 176 D-----DDDDFDDEEAEEKAPVKKSIRDTPAKNAQKSNQNGKDSKPSSTPRSKGQESFKK 230
           D      D D ++EE ++ A   + ++  P  +  K     K    +     +  +   +
Sbjct: 232 DTGSTSSDSDSEEEEGKQTALASRFLKKAPTTDEDKKAAEKKREDKAKKKHDRKSKRLDE 291

Query: 231 QEK 233
           +E+
Sbjct: 292 EEE 294



 Score = 33.1 bits (74), Expect = 0.25
 Identities = 29/116 (25%), Positives = 53/116 (45%), Gaps = 19/116 (16%)

Query: 159 AADEDDDDDDEEDDDEDDDDDDFDDEEAEEKAPVKKSIRDTPA----KNAQKSNQNGKDS 214
           +ADED + ++E+ +   D+D   +DE+    A   K   + P+    K  +K +   +DS
Sbjct: 166 SADEDAEKNEEDSEGSSDED---EDEDGVSAATFLKKKSEAPSGESRKFLKKMDDEDEDS 222

Query: 215 KPSSTPR-----SKGQESFKKQEKTPKT-------PKGPSSVEDIKAKMQASIEKA 258
           + S         S   +S  ++E+  +T        K P++ ED KA  +   +KA
Sbjct: 223 EDSEDDEDWDTGSTSSDSDSEEEEGKQTALASRFLKKAPTTDEDKKAAEKKREDKA 278


>gi|83700233 eukaryotic translation initiation factor 3, subunit C
           [Homo sapiens]
          Length = 913

 Score = 52.4 bits (124), Expect = 4e-07
 Identities = 35/123 (28%), Positives = 60/123 (48%), Gaps = 12/123 (9%)

Query: 120 EEDAES---EDEEEEDVKLLSISGKRS-APGGGSKVPQKKVKLAADEDDDDDDEEDDDED 175
           EED+E    EDE+E+ V   +   K+S AP G S+   K +K   DED+D +D EDD++ 
Sbjct: 175 EEDSEGSSDEDEDEDGVSAATFLKKKSEAPSGESR---KFLKKMDDEDEDSEDSEDDEDW 231

Query: 176 D-----DDDDFDDEEAEEKAPVKKSIRDTPAKNAQKSNQNGKDSKPSSTPRSKGQESFKK 230
           D      D D ++EE ++ A   + ++  P  +  K     K    +     +  +   +
Sbjct: 232 DTGSTSSDSDSEEEEGKQTALASRFLKKAPTTDEDKKAAEKKREDKAKKKHDRKSKRLDE 291

Query: 231 QEK 233
           +E+
Sbjct: 292 EEE 294



 Score = 33.1 bits (74), Expect = 0.25
 Identities = 29/116 (25%), Positives = 53/116 (45%), Gaps = 19/116 (16%)

Query: 159 AADEDDDDDDEEDDDEDDDDDDFDDEEAEEKAPVKKSIRDTPA----KNAQKSNQNGKDS 214
           +ADED + ++E+ +   D+D   +DE+    A   K   + P+    K  +K +   +DS
Sbjct: 166 SADEDAEKNEEDSEGSSDED---EDEDGVSAATFLKKKSEAPSGESRKFLKKMDDEDEDS 222

Query: 215 KPSSTPR-----SKGQESFKKQEKTPKT-------PKGPSSVEDIKAKMQASIEKA 258
           + S         S   +S  ++E+  +T        K P++ ED KA  +   +KA
Sbjct: 223 EDSEDDEDWDTGSTSSDSDSEEEEGKQTALASRFLKKAPTTDEDKKAAEKKREDKA 278



 Score = 28.1 bits (61), Expect = 8.0
 Identities = 19/78 (24%), Positives = 35/78 (44%), Gaps = 1/78 (1%)

Query: 118 AVEEDAESEDEEEEDVKLLS-ISGKRSAPGGGSKVPQKKVKLAADEDDDDDDEEDDDEDD 176
           +   D++SE+EE +   L S    K        K  +KK +  A +  D   +  D+E++
Sbjct: 235 STSSDSDSEEEEGKQTALASRFLKKAPTTDEDKKAAEKKREDKAKKKHDRKSKRLDEEEE 294

Query: 177 DDDDFDDEEAEEKAPVKK 194
           D++  + E      P+ K
Sbjct: 295 DNEGGEWERVRGGVPLVK 312


>gi|4503525 eukaryotic translation initiation factor 3, subunit C
           [Homo sapiens]
          Length = 913

 Score = 52.4 bits (124), Expect = 4e-07
 Identities = 35/123 (28%), Positives = 60/123 (48%), Gaps = 12/123 (9%)

Query: 120 EEDAES---EDEEEEDVKLLSISGKRS-APGGGSKVPQKKVKLAADEDDDDDDEEDDDED 175
           EED+E    EDE+E+ V   +   K+S AP G S+   K +K   DED+D +D EDD++ 
Sbjct: 175 EEDSEGSSDEDEDEDGVSAATFLKKKSEAPSGESR---KFLKKMDDEDEDSEDSEDDEDW 231

Query: 176 D-----DDDDFDDEEAEEKAPVKKSIRDTPAKNAQKSNQNGKDSKPSSTPRSKGQESFKK 230
           D      D D ++EE ++ A   + ++  P  +  K     K    +     +  +   +
Sbjct: 232 DTGSTSSDSDSEEEEGKQTALASRFLKKAPTTDEDKKAAEKKREDKAKKKHDRKSKRLDE 291

Query: 231 QEK 233
           +E+
Sbjct: 292 EEE 294



 Score = 33.1 bits (74), Expect = 0.25
 Identities = 29/116 (25%), Positives = 53/116 (45%), Gaps = 19/116 (16%)

Query: 159 AADEDDDDDDEEDDDEDDDDDDFDDEEAEEKAPVKKSIRDTPA----KNAQKSNQNGKDS 214
           +ADED + ++E+ +   D+D   +DE+    A   K   + P+    K  +K +   +DS
Sbjct: 166 SADEDAEKNEEDSEGSSDED---EDEDGVSAATFLKKKSEAPSGESRKFLKKMDDEDEDS 222

Query: 215 KPSSTPR-----SKGQESFKKQEKTPKT-------PKGPSSVEDIKAKMQASIEKA 258
           + S         S   +S  ++E+  +T        K P++ ED KA  +   +KA
Sbjct: 223 EDSEDDEDWDTGSTSSDSDSEEEEGKQTALASRFLKKAPTTDEDKKAAEKKREDKA 278



 Score = 28.1 bits (61), Expect = 8.0
 Identities = 19/78 (24%), Positives = 35/78 (44%), Gaps = 1/78 (1%)

Query: 118 AVEEDAESEDEEEEDVKLLS-ISGKRSAPGGGSKVPQKKVKLAADEDDDDDDEEDDDEDD 176
           +   D++SE+EE +   L S    K        K  +KK +  A +  D   +  D+E++
Sbjct: 235 STSSDSDSEEEEGKQTALASRFLKKAPTTDEDKKAAEKKREDKAKKKHDRKSKRLDEEEE 294

Query: 177 DDDDFDDEEAEEKAPVKK 194
           D++  + E      P+ K
Sbjct: 295 DNEGGEWERVRGGVPLVK 312


>gi|166795264 AE binding protein 2 isoform b [Homo sapiens]
          Length = 517

 Score = 52.0 bits (123), Expect = 5e-07
 Identities = 32/130 (24%), Positives = 59/130 (45%), Gaps = 13/130 (10%)

Query: 120 EEDAESEDEEEEDVKLLSISGKRSAPGGG---------SKVPQKKVKLAADEDDDDDDEE 170
           EE+ E E+ E E V  L ++G     GGG         ++   +    +A +  +D+DEE
Sbjct: 41  EEEEEEEEAEAEAVAALLLNGGSGGGGGGGGGGVGGGEAETMSEPSPESASQAGEDEDEE 100

Query: 171 DDDEDDDDDDFDDEEAEEKAPVKKSIRDTPAKNAQKSNQNGKDSKPSSTPRSKGQESFKK 230
           +DDE+++D+       EE++  +  +      +   S+   +   P +   S G    K+
Sbjct: 101 EDDEEEEDESSSSGGGEEESSAESLV----GSSGGSSSDETRSLSPGAASSSSGDGDGKE 156

Query: 231 QEKTPKTPKG 240
             + PK P+G
Sbjct: 157 GLEEPKGPRG 166


>gi|166795262 AE binding protein 2 isoform a [Homo sapiens]
          Length = 503

 Score = 52.0 bits (123), Expect = 5e-07
 Identities = 32/130 (24%), Positives = 59/130 (45%), Gaps = 13/130 (10%)

Query: 120 EEDAESEDEEEEDVKLLSISGKRSAPGGG---------SKVPQKKVKLAADEDDDDDDEE 170
           EE+ E E+ E E V  L ++G     GGG         ++   +    +A +  +D+DEE
Sbjct: 41  EEEEEEEEAEAEAVAALLLNGGSGGGGGGGGGGVGGGEAETMSEPSPESASQAGEDEDEE 100

Query: 171 DDDEDDDDDDFDDEEAEEKAPVKKSIRDTPAKNAQKSNQNGKDSKPSSTPRSKGQESFKK 230
           +DDE+++D+       EE++  +  +      +   S+   +   P +   S G    K+
Sbjct: 101 EDDEEEEDESSSSGGGEEESSAESLV----GSSGGSSSDETRSLSPGAASSSSGDGDGKE 156

Query: 231 QEKTPKTPKG 240
             + PK P+G
Sbjct: 157 GLEEPKGPRG 166


>gi|42740903 MTERF domain containing 2 [Homo sapiens]
          Length = 381

 Score = 51.2 bits (121), Expect = 9e-07
 Identities = 23/35 (65%), Positives = 29/35 (82%), Gaps = 3/35 (8%)

Query: 157 KLAADEDDDDDDEEDDDEDD---DDDDFDDEEAEE 188
           + + DED+DDDDEED+DEDD   DDDD DD+EAE+
Sbjct: 336 RASLDEDEDDDDEEDNDEDDNDEDDDDEDDDEAED 370



 Score = 44.3 bits (103), Expect = 1e-04
 Identities = 21/59 (35%), Positives = 35/59 (59%)

Query: 129 EEEDVKLLSISGKRSAPGGGSKVPQKKVKLAADEDDDDDDEEDDDEDDDDDDFDDEEAE 187
           EEE+ +  +   KR++         ++     D D+DDDDE+DD+ +D+D+D DD+E E
Sbjct: 323 EEEESESSTSDDKRASLDEDEDDDDEEDNDEDDNDEDDDDEDDDEAEDNDEDEDDDEEE 381



 Score = 43.5 bits (101), Expect = 2e-04
 Identities = 21/71 (29%), Positives = 37/71 (52%), Gaps = 27/71 (38%)

Query: 118 AVEEDAESEDEEEEDVKLLSISGKRSAPGGGSKVPQKKVKLAADEDDDDDDEEDDDEDDD 177
           +++ED + +DEE+ D                            D++D+DDD+EDDDE +D
Sbjct: 338 SLDEDEDDDDEEDND---------------------------EDDNDEDDDDEDDDEAED 370

Query: 178 DDDFDDEEAEE 188
           +D+ +D++ EE
Sbjct: 371 NDEDEDDDEEE 381



 Score = 29.6 bits (65), Expect = 2.7
 Identities = 14/42 (33%), Positives = 24/42 (57%), Gaps = 7/42 (16%)

Query: 155 KVKLAADEDDDDDDEEDD-------DEDDDDDDFDDEEAEEK 189
           K  LA +E++ +    DD       DEDDDD++ +DE+  ++
Sbjct: 317 KKLLAREEEESESSTSDDKRASLDEDEDDDDEEDNDEDDNDE 358


>gi|148596949 nucleolar and coiled-body phosphoprotein 1 [Homo
           sapiens]
          Length = 699

 Score = 51.2 bits (121), Expect = 9e-07
 Identities = 35/126 (27%), Positives = 52/126 (41%), Gaps = 10/126 (7%)

Query: 118 AVEEDAESEDEEEEDV-----KLLSISGKRSAPGGGSKVPQKKVKLAADEDDDDDDEEDD 172
           A   D+E   EEEE+V     K  ++  KR     G    +     +++E  DDDDEED 
Sbjct: 82  ASSSDSEDSSEEEEEVQGPPAKKAAVPAKRVGLPPGKAAAKASESSSSEESSDDDDEEDQ 141

Query: 173 DEDDDDDDFDDEEAEEKAPVKKSIRDTPAKNAQKSNQNGKDSKPSSTPRSKGQESFKKQE 232
            +         +    KAP KK+       ++   ++  K+ KP  TP      + K Q 
Sbjct: 142 KKQPVQKGVKPQAKAAKAPPKKAKSSDSDSDSSSEDEPPKNQKPKITP-----VTVKAQT 196

Query: 233 KTPKTP 238
           K P  P
Sbjct: 197 KAPPKP 202



 Score = 50.4 bits (119), Expect = 1e-06
 Identities = 36/183 (19%), Positives = 76/183 (41%), Gaps = 3/183 (1%)

Query: 61  EAEAMNYEGSPIKVTLATLKMSVQPTVSLGGFEITPPVVLRLKCGSGPVHISGQHLVAVE 120
           ++++   + +P K    T   S +P V+     + P    +   G G   ++ +   +  
Sbjct: 367 DSDSSEDDEAPSKPAGTTKNSSNKPAVTTKSPAVKPAAAPKQPVGGGQKLLTRKADSSSS 426

Query: 121 EDAESEDEEEEDVKLLSISGKRSAPGGGSKVPQKKVKLAADEDDDDDDEEDDDEDDDDDD 180
           E+  S  EEE+  K+++ +  ++       +P K+    + +   D D    +E+++   
Sbjct: 427 EEESSSSEEEKTKKMVATTKPKATAKAALSLPAKQAPQGSRDSSSDSDSSSSEEEEEK-- 484

Query: 181 FDDEEAEEKAPVKKSIRDTPAKNAQKSNQNGKDSKPSSTPRSKGQESFKKQEKTPKTPKG 240
              + A +K P K +    P+K A       + S  SS+  S  +E  K + K    P+ 
Sbjct: 485 -TSKSAVKKKPQKVAGGAAPSKPASAKKGKAESSNSSSSDDSSEEEEEKLKGKGSPRPQA 543

Query: 241 PSS 243
           P +
Sbjct: 544 PKA 546



 Score = 43.1 bits (100), Expect = 2e-04
 Identities = 37/135 (27%), Positives = 57/135 (42%), Gaps = 21/135 (15%)

Query: 121 EDAESEDEEEEDVKLLSISGKRSAPGGGSKVPQKKV------KLAADEDDDDDDEEDDDE 174
           ED+ S++EEE+   + +  G  S+    S  P KK       K A ++    +  ED  +
Sbjct: 268 EDSSSDEEEEQKKPMKNKPGPYSSVPPPSAPPPKKSLGTQPPKKAVEKQQPVESSEDSSD 327

Query: 175 DDDDDDFDDEEAEEKAPVKKSI-----RDTPAKNAQKSNQNGKDSKPS------STPRSK 223
           + D       E E+K P K  +     +  PAK A +S+ +  DS  S      S P   
Sbjct: 328 ESDSSS----EEEKKPPTKAVVSKATTKPPPAKKAAESSSDSSDSDSSEDDEAPSKPAGT 383

Query: 224 GQESFKKQEKTPKTP 238
            + S  K   T K+P
Sbjct: 384 TKNSSNKPAVTTKSP 398



 Score = 38.1 bits (87), Expect = 0.008
 Identities = 31/159 (19%), Positives = 57/159 (35%), Gaps = 3/159 (1%)

Query: 103 KCGSGPVHISGQHLVAVEEDAESEDEEEEDVKLLSISGKR---SAPGGGSKVPQKKVKLA 159
           K  +G    S     +     +SE+E+       ++  K+    AP   +  P +K   +
Sbjct: 208 KIANGKAASSSSSSSSSSSSDDSEEEKAAATPKKTVPKKQVVAKAPVKAATTPTRKSSSS 267

Query: 160 ADEDDDDDDEEDDDEDDDDDDFDDEEAEEKAPVKKSIRDTPAKNAQKSNQNGKDSKPSST 219
            D   D+++E+     +    +         P KKS+   P K A +  Q  + S+ SS 
Sbjct: 268 EDSSSDEEEEQKKPMKNKPGPYSSVPPPSAPPPKKSLGTQPPKKAVEKQQPVESSEDSSD 327

Query: 220 PRSKGQESFKKQEKTPKTPKGPSSVEDIKAKMQASIEKA 258
                 E  KK        K  +     K   ++S + +
Sbjct: 328 ESDSSSEEEKKPPTKAVVSKATTKPPPAKKAAESSSDSS 366



 Score = 36.2 bits (82), Expect = 0.029
 Identities = 27/119 (22%), Positives = 49/119 (41%), Gaps = 8/119 (6%)

Query: 120 EEDAESEDEEEEDVKLLSISGKRSAPGGGSKVPQKKVKLAADEDDDDDDEEDDDEDDDDD 179
           E D+ SE+E++   K +        P      P KK   ++ +  D D  EDD+      
Sbjct: 328 ESDSSSEEEKKPPTKAVVSKATTKPP------PAKKAAESSSDSSDSDSSEDDEAPSKPA 381

Query: 180 DFDDEEAEEKAPVKKSIRDTPAKNAQKSNQNGKD--SKPSSTPRSKGQESFKKQEKTPK 236
                 + + A   KS    PA   ++    G+   ++ + +  S+ + S  ++EKT K
Sbjct: 382 GTTKNSSNKPAVTTKSPAVKPAAAPKQPVGGGQKLLTRKADSSSSEEESSSSEEEKTKK 440



 Score = 32.7 bits (73), Expect = 0.32
 Identities = 26/127 (20%), Positives = 50/127 (39%), Gaps = 4/127 (3%)

Query: 121 EDAESEDEEEEDVKLLSISGKRSAPGGGSKVPQKKVKLAADEDDDDDDEEDDDEDDDDDD 180
           + + SE+EEE+  K       +   GG +       K    E  +    +D  E++++  
Sbjct: 474 DSSSSEEEEEKTSKSAVKKKPQKVAGGAAPSKPASAKKGKAESSNSSSSDDSSEEEEEKL 533

Query: 181 FDDEEAEEKAPVKKSIRDTPAKN---AQKSNQNGKDSKPSSTPRSK-GQESFKKQEKTPK 236
                   +AP         A+N   A+ S +  ++ K ++   SK G    +KQ +  K
Sbjct: 534 KGKGSPRPQAPKANGTSALTAQNGKAAKNSEEEEEEKKKAAVVVSKSGSLKKRKQNEAAK 593

Query: 237 TPKGPSS 243
             + P +
Sbjct: 594 EAETPQA 600



 Score = 28.5 bits (62), Expect = 6.1
 Identities = 29/136 (21%), Positives = 51/136 (37%), Gaps = 27/136 (19%)

Query: 120 EEDAESEDE--EEEDVKLLSISGK----------RSAPGGGSKVPQKKVKLAADEDDDDD 167
           + D+ SEDE  + +  K+  ++ K          R+AP   +         ++     DD
Sbjct: 170 DSDSSSEDEPPKNQKPKITPVTVKAQTKAPPKPARAAPKIANGKAASSSSSSSSSSSSDD 229

Query: 168 DEEDDDEDDDDDDFDDEEAEEKAPVKKSIRDTPAKNAQKSNQNGKDSKPSSTPRSKGQES 227
            EE+            ++   KAPVK +   TP + +  S  +  D +            
Sbjct: 230 SEEEKAAATPKKTVPKKQVVAKAPVKAA--TTPTRKSSSSEDSSSDEE------------ 275

Query: 228 FKKQEKTPKTPKGPSS 243
            ++Q+K  K   GP S
Sbjct: 276 -EEQKKPMKNKPGPYS 290


>gi|119709834 castor homolog 1, zinc finger isoform a [Homo sapiens]
          Length = 1759

 Score = 50.1 bits (118), Expect = 2e-06
 Identities = 28/82 (34%), Positives = 46/82 (56%), Gaps = 22/82 (26%)

Query: 113  GQHLVAVEEDAESEDEEEEDVKLLSISGKRSAPGGGSKVPQKKVKLAADEDDDDDDEEDD 172
            G    A      S+++EEE+++L                P+++   A D++D+DDDE+DD
Sbjct: 1662 GAAAAAAAAGESSQEDEEEELEL----------------PEEE---AEDDEDEDDDEDDD 1702

Query: 173  DEDDDDDDFDDE---EAEEKAP 191
            DEDDD+DD D++   ++EE  P
Sbjct: 1703 DEDDDEDDDDEDLRTDSEESLP 1724



 Score = 45.4 bits (106), Expect = 5e-05
 Identities = 19/53 (35%), Positives = 39/53 (73%), Gaps = 1/53 (1%)

Query: 153  QKKVKLAADEDDDDDDEEDD-DEDDDDDDFDDEEAEEKAPVKKSIRDTPAKNA 204
            +++++L  +E +DD+DE+DD D+DD+DDD DD++ + +   ++S+ +  A+ A
Sbjct: 1679 EEELELPEEEAEDDEDEDDDEDDDDEDDDEDDDDEDLRTDSEESLPEAAAEAA 1731


>gi|210032580 SET domain containing 1B [Homo sapiens]
          Length = 1923

 Score = 48.9 bits (115), Expect = 4e-06
 Identities = 36/160 (22%), Positives = 70/160 (43%), Gaps = 22/160 (13%)

Query: 120  EEDAESEDEEEEDVKLLSIS-GKRSAPGGG-SKVPQKKVKLAA----------------- 160
            EED ESE E + D+        KR   G G  + P + ++L +                 
Sbjct: 989  EEDEESERERDRDMADTPCELAKRDPKGVGVRRRPARPLELDSGGEEDEKESLSEEQEST 1048

Query: 161  ---DEDDDDDDEEDDDEDDDDDDFDDEEAEEKAPVKKSIRDTPAKNAQKSNQNGKDSKPS 217
               +E +++++EEDDD+DD DD  + E  +E   + ++       + ++   +   SK  
Sbjct: 1049 EEEEEAEEEEEEEDDDDDDSDDRDESENDDEDTALSEASEKDEGDSDEEETVSIVTSKAE 1108

Query: 218  STPRSKGQESFKKQEKTPKTPKGPSSVEDIKAKMQASIEK 257
            +T  S+  ES + +  +  +P      E++ A+ +   E+
Sbjct: 1109 ATSSSESSESSEFESSSESSPSSSEDEEEVVAREEEEEEE 1148



 Score = 43.9 bits (102), Expect = 1e-04
 Identities = 30/125 (24%), Positives = 51/125 (40%), Gaps = 37/125 (29%)

Query: 118  AVEEDAESEDEEEEDVKLLSISGKRSAPGGGSKVPQKKVKLAADEDDDDDDEEDDDEDDD 177
            + EE+ E+E+EEEE+                            D+DDDD D+ D+ E+DD
Sbjct: 1047 STEEEEEAEEEEEEE----------------------------DDDDDDSDDRDESENDD 1078

Query: 178  DD---------DFDDEEAEEKAPVKKSIRDTPAKNAQKSNQNGKDSKPSSTPRSKGQESF 228
            +D         D  D + EE   +  S  +  + +    +   + S  SS   S+ +E  
Sbjct: 1079 EDTALSEASEKDEGDSDEEETVSIVTSKAEATSSSESSESSEFESSSESSPSSSEDEEEV 1138

Query: 229  KKQEK 233
              +E+
Sbjct: 1139 VAREE 1143



 Score = 33.9 bits (76), Expect = 0.15
 Identities = 28/114 (24%), Positives = 51/114 (44%), Gaps = 4/114 (3%)

Query: 133  VKLLSISGKRSAPGGGSKVPQKKVKLAADEDDDDDDEEDDDEDDDDDDFDDEEAEEKAPV 192
            ++L S   KR  P   +    +K +L      D++DEE + E D D      E  ++ P 
Sbjct: 957  IRLPSFKVKRKEPPDTTSSGDQK-RLRPSTSVDEEDEESERERDRDMADTPCELAKRDPK 1015

Query: 193  KKSIRDTPAKNAQKSNQNGKDSKPSSTPRSKGQESFKKQEKTPKTPKGPSSVED 246
               +R  PA+  +  +   +D K S    S+ QES +++E+  +  +     +D
Sbjct: 1016 GVGVRRRPARPLELDSGGEEDEKES---LSEEQESTEEEEEAEEEEEEEDDDDD 1066



 Score = 32.0 bits (71), Expect = 0.55
 Identities = 27/126 (21%), Positives = 46/126 (36%), Gaps = 38/126 (30%)

Query: 120  EEDAESEDEEEEDVKLLSISGKRSAPGGGSKVPQKKVKLAADEDDDDDDEEDDDED---- 175
            EE+AE E+EEE+D                            D+ DD D+ E+DDED    
Sbjct: 1051 EEEAEEEEEEEDDDD--------------------------DDSDDRDESENDDEDTALS 1084

Query: 176  --------DDDDDFDDEEAEEKAPVKKSIRDTPAKNAQKSNQNGKDSKPSSTPRSKGQES 227
                    D D++        KA    S   + +   + S+++   S          +E 
Sbjct: 1085 EASEKDEGDSDEEETVSIVTSKAEATSSSESSESSEFESSSESSPSSSEDEEEVVAREEE 1144

Query: 228  FKKQEK 233
             +++E+
Sbjct: 1145 EEEEEE 1150



 Score = 28.9 bits (63), Expect = 4.7
 Identities = 15/79 (18%), Positives = 39/79 (49%), Gaps = 4/79 (5%)

Query: 116  LVAVEEDAESEDEEEEDVKLLSISGKRSAPGGGSKVPQKKVKLAADEDDDDDDEE----D 171
            L    E  E + +EEE V +++   + ++    S+  + +    +     +D+EE    +
Sbjct: 1083 LSEASEKDEGDSDEEETVSIVTSKAEATSSSESSESSEFESSSESSPSSSEDEEEVVARE 1142

Query: 172  DDEDDDDDDFDDEEAEEKA 190
            ++E++++++   EE+   A
Sbjct: 1143 EEEEEEEEEMVAEESMASA 1161


>gi|239744307 PREDICTED: similar to hCG1991922 [Homo sapiens]
          Length = 486

 Score = 48.5 bits (114), Expect = 6e-06
 Identities = 21/76 (27%), Positives = 44/76 (57%)

Query: 120 EEDAESEDEEEEDVKLLSISGKRSAPGGGSKVPQKKVKLAADEDDDDDDEEDDDEDDDDD 179
           +  A+ +++ E+D+      GK  A   G     K  K   +E++++D+E++++E D+D+
Sbjct: 282 KRSAKLKEKYEKDIAAYRAKGKHDAANNGVVKAAKSKKKKEEEENEEDEEDEEEEKDEDE 341

Query: 180 DFDDEEAEEKAPVKKS 195
           D +D+E EE    ++S
Sbjct: 342 DEEDDEDEEDGDDEQS 357


>gi|17975763 myelin transcription factor 1 [Homo sapiens]
          Length = 1121

 Score = 48.5 bits (114), Expect = 6e-06
 Identities = 36/134 (26%), Positives = 67/134 (50%), Gaps = 23/134 (17%)

Query: 120 EEDAESEDEEEEDVKLLSISGKRSAPGGGSKVPQKKVKLAADEDDDDDDEEDDDEDDDDD 179
           EED E E+EEEE+                     ++ +   +E++++++EE+++E+++++
Sbjct: 259 EEDEEEEEEEEEE---------------------EEDEEEEEEEEEEEEEEEEEEEEEEE 297

Query: 180 DFDDEEAEEKAPVKKSIRDTPAKNAQKSNQNGKDSKPSSTPR-SKGQESFKKQEKTPKTP 238
           + ++EE EE AP      DT   +AQK+ +      PS  P  S   E     +K   T 
Sbjct: 298 EEEEEEEEEAAPDVIFQEDTSHTSAQKAPELRGPESPSPKPEYSVIVEVRSDDDKDEDTH 357

Query: 239 KGPSSVEDIKAKMQ 252
              S+V D +++MQ
Sbjct: 358 SRKSTVTD-ESEMQ 370



 Score = 42.4 bits (98), Expect = 4e-04
 Identities = 33/153 (21%), Positives = 72/153 (47%), Gaps = 23/153 (15%)

Query: 103 KCGSGPVHISGQHLVAVEEDAESEDEE-------EEDVKLLSISGKRSAP--------GG 147
           K G G VH+    L    E A SE+ E       E+  +++ ++ +RS            
Sbjct: 189 KPGPGIVHL----LQEAAEGAASEEGEKGLFIQPEDAEEVVEVTTERSQDLCPQSLEDAA 244

Query: 148 GSKVPQKKVKLAADEDDDDDDEEDDDEDDDDDDFDDEEAEEKAPVKKSIRDTPAKNAQKS 207
             +  ++K  L+ +E+D++++EE+++E++D+++ ++EE EE+   ++   +   +  ++ 
Sbjct: 245 SEESSKQKGILSHEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEEEEEEEE 304

Query: 208 NQNGKD----SKPSSTPRSKGQESFKKQEKTPK 236
            +   D       S T   K  E    +  +PK
Sbjct: 305 EEAAPDVIFQEDTSHTSAQKAPELRGPESPSPK 337



 Score = 30.4 bits (67), Expect = 1.6
 Identities = 26/126 (20%), Positives = 48/126 (38%), Gaps = 9/126 (7%)

Query: 120 EEDAESEDEEEEDVKLLSI---------SGKRSAPGGGSKVPQKKVKLAADEDDDDDDEE 170
           EE+ E E+EEEE+     +         S +++    G + P  K + +   +   DD++
Sbjct: 293 EEEEEEEEEEEEEEAAPDVIFQEDTSHTSAQKAPELRGPESPSPKPEYSVIVEVRSDDDK 352

Query: 171 DDDEDDDDDDFDDEEAEEKAPVKKSIRDTPAKNAQKSNQNGKDSKPSSTPRSKGQESFKK 230
           D+D         DE   +    + ++       A K+ Q     +P   P  + Q    +
Sbjct: 353 DEDTHSRKSTVTDESEMQDMMTRGNLGLLEQAIALKAEQVRTVCEPGCPPAEQSQLGLGE 412

Query: 231 QEKTPK 236
             K  K
Sbjct: 413 PGKAAK 418


>gi|156104891 general transcription factor IIF, polypeptide 1, 74kDa
           [Homo sapiens]
          Length = 517

 Score = 48.5 bits (114), Expect = 6e-06
 Identities = 34/130 (26%), Positives = 63/130 (48%), Gaps = 14/130 (10%)

Query: 121 EDAESEDEEEEDVKLLS--ISGKRSAPGGGSKVPQKKV-KLAADEDDDDDDEEDDDEDDD 177
           ED++  D E ++V  +S   S  +  P   +K PQ++      DE  D  +E ++++  +
Sbjct: 259 EDSDDGDFEGQEVDYMSDGSSSSQEEPESKAKAPQQEEGPKGVDEQSDSSEESEEEKPPE 318

Query: 178 DDDFDDEEAEEKAPVKKSIRDTPAKNAQKSNQNGKDSKPSSTPRSKGQESFKKQEKTP-- 235
           +D  ++EE +   P +K  R   ++ +  S ++  DS+ SS         F  ++KTP  
Sbjct: 319 EDKEEEEEKKAPTPQEKKRRKDSSEESDSSEESDIDSEASSA-------LFMAKKKTPPK 371

Query: 236 --KTPKGPSS 243
             + P G SS
Sbjct: 372 RERKPSGGSS 381



 Score = 40.8 bits (94), Expect = 0.001
 Identities = 28/123 (22%), Positives = 54/123 (43%), Gaps = 2/123 (1%)

Query: 119 VEEDAESEDEEEEDVKLLSISGKRS--APGGGSKVPQKKVKLAADEDDDDDDEEDDDEDD 176
           +E  +++ D   E+   +  + K++  A GG  K  +K     A ED DD D E  + D 
Sbjct: 214 LEMSSDASDASGEEGGRVPKAKKKAPLAKGGRKKKKKKGSDDEAFEDSDDGDFEGQEVDY 273

Query: 177 DDDDFDDEEAEEKAPVKKSIRDTPAKNAQKSNQNGKDSKPSSTPRSKGQESFKKQEKTPK 236
             D     + E ++  K   ++   K   + + + ++S+    P    +E  +K+  TP+
Sbjct: 274 MSDGSSSSQEEPESKAKAPQQEEGPKGVDEQSDSSEESEEEKPPEEDKEEEEEKKAPTPQ 333

Query: 237 TPK 239
             K
Sbjct: 334 EKK 336



 Score = 38.9 bits (89), Expect = 0.005
 Identities = 34/132 (25%), Positives = 61/132 (46%), Gaps = 14/132 (10%)

Query: 130 EEDVKLLSISGKRSAPGGGSKVPQ--KKVKLAAD-----EDDDDDDEEDDDEDDDDDDFD 182
           E+D+++ S +   S   GG +VP+  KK  LA       +    DDE    ED DD DF+
Sbjct: 211 EDDLEMSSDASDASGEEGG-RVPKAKKKAPLAKGGRKKKKKKGSDDEAF--EDSDDGDFE 267

Query: 183 DEEAEEKAPVKKSIRDTPAKNA----QKSNQNGKDSKPSSTPRSKGQESFKKQEKTPKTP 238
            +E +  +    S ++ P   A    Q+    G D +  S+  S+ ++  ++ ++  +  
Sbjct: 268 GQEVDYMSDGSSSSQEEPESKAKAPQQEEGPKGVDEQSDSSEESEEEKPPEEDKEEEEEK 327

Query: 239 KGPSSVEDIKAK 250
           K P+  E  + K
Sbjct: 328 KAPTPQEKKRRK 339



 Score = 35.0 bits (79), Expect = 0.065
 Identities = 42/168 (25%), Positives = 70/168 (41%), Gaps = 46/168 (27%)

Query: 124 ESEDEEEEDVKLLSISGKRSAPGGGSKVPQKKVKLAADEDDDDDDEED------------ 171
           E+E+E E   K+L+           S + Q+++K   D+D D+D+EE             
Sbjct: 159 EAEEEWERRNKVLNHF---------SIMQQRRLK---DQDQDEDEEEKEKRGRRKASELR 206

Query: 172 --DDEDD-----DDDDFDDEE------AEEKAPV---------KKSIRDTPAKNAQKSNQ 209
             D EDD     D  D   EE      A++KAP+         KK   D   +++   + 
Sbjct: 207 IHDLEDDLEMSSDASDASGEEGGRVPKAKKKAPLAKGGRKKKKKKGSDDEAFEDSDDGDF 266

Query: 210 NGKDSKPSSTPRSKGQESFKKQEKTPKTPKGPSSVEDIKAKMQASIEK 257
            G++    S   S  QE  + + K P+  +GP  V++     + S E+
Sbjct: 267 EGQEVDYMSDGSSSSQEEPESKAKAPQQEEGPKGVDEQSDSSEESEEE 314



 Score = 29.6 bits (65), Expect = 2.7
 Identities = 29/124 (23%), Positives = 54/124 (43%), Gaps = 16/124 (12%)

Query: 120 EEDAESEDEEEEDVKLLSISGKRSAPGGGSKVPQKKVKLAADEDDDDDDEEDDDEDDDDD 179
           EE    ED+EEE+ K      K   P       +KK +  + E+ D  +E D D +    
Sbjct: 313 EEKPPEEDKEEEEEK------KAPTP------QEKKRRKDSSEESDSSEESDIDSEASSA 360

Query: 180 DFDDEEAEEKAPVKKSIRDTPAKNAQKSNQNGKDSKPSSTPRSKGQESFKKQEKTPKTPK 239
            F    A++K P K+  R     +++ +++ G  S    +  S  + +  K E+  +  +
Sbjct: 361 LF---MAKKKTPPKRE-RKPSGGSSRGNSRPGTPSAEGGSTSSTLRAAASKLEQGKRVSE 416

Query: 240 GPSS 243
            P++
Sbjct: 417 MPAA 420


>gi|187960109 RNA binding motif protein 28 [Homo sapiens]
          Length = 759

 Score = 48.5 bits (114), Expect = 6e-06
 Identities = 38/148 (25%), Positives = 73/148 (49%), Gaps = 23/148 (15%)

Query: 123 AESEDEEEEDVKLLSISGKRSAPGGGSKVPQKKVKLAADEDDDDDDEEDDDEDDDDDDFD 182
           A ++D+ ++   + +I  ++S      +  +KK +   D +++++D++DDD+D++D  FD
Sbjct: 189 AVAKDKYKDTQSVSAIGEEKSHESKHQESVKKKGREEEDMEEEENDDDDDDDDEEDGVFD 248

Query: 183 DEEAEE---KAPVKKSI--------RDTPAKNAQKSNQ-----------NGKDSKPSSTP 220
           DE+ EE   ++ V K +        R  PAK++  S +           +G++   S T 
Sbjct: 249 DEDEEEENIESKVTKPVQIQKRAVKRPAPAKSSDHSEEDSDLEESDSIDDGEELAQSDT- 307

Query: 221 RSKGQESFKKQEKTPKTPKGPSSVEDIK 248
            ++ QE    Q    K  K PS V + K
Sbjct: 308 STEEQEDKAVQVSNKKKRKLPSDVNEGK 335



 Score = 33.9 bits (76), Expect = 0.15
 Identities = 25/81 (30%), Positives = 37/81 (45%), Gaps = 16/81 (19%)

Query: 120 EEDAESEDEEEED----------VKLLSISGKRSAPGGGSKVPQKKVKLAADEDDDDDDE 169
           EED   +DE+EE+          V++   + KR AP   S   ++      D D ++ D 
Sbjct: 242 EEDGVFDDEDEEEENIESKVTKPVQIQKRAVKRPAPAKSSDHSEE------DSDLEESDS 295

Query: 170 EDDDEDDDDDDFDDEEAEEKA 190
            DD E+    D   EE E+KA
Sbjct: 296 IDDGEELAQSDTSTEEQEDKA 316


>gi|21735415 centromere protein B [Homo sapiens]
          Length = 599

 Score = 48.1 bits (113), Expect = 7e-06
 Identities = 32/87 (36%), Positives = 46/87 (52%), Gaps = 15/87 (17%)

Query: 117 VAVEEDAESEDEEEEDVKLLS--------ISGKRSAPGG-GSKVPQKKVK------LAAD 161
           V  E D +S++EEEED +  S          G   A G  G+   Q++ +      L   
Sbjct: 448 VEEEGDVDSDEEEEEDEESSSEGLEAEDWAQGVVEAGGSFGAYGAQEEAQCPTLHFLEGG 507

Query: 162 EDDDDDDEEDDDEDDDDDDFDDEEAEE 188
           ED D D EE+DDE++DD+D DD++ EE
Sbjct: 508 EDSDSDSEEEDDEEEDDEDEDDDDDEE 534



 Score = 35.4 bits (80), Expect = 0.050
 Identities = 18/65 (27%), Positives = 31/65 (47%), Gaps = 28/65 (43%)

Query: 115 HLVAVEEDAESEDEEEEDVKLLSISGKRSAPGGGSKVPQKKVKLAADEDDDDDDEEDDDE 174
           H +   ED++S+ EEE+D                            +E+DD+D+++DDDE
Sbjct: 502 HFLEGGEDSDSDSEEEDD----------------------------EEEDDEDEDDDDDE 533

Query: 175 DDDDD 179
           +D D+
Sbjct: 534 EDGDE 538



 Score = 35.0 bits (79), Expect = 0.065
 Identities = 22/71 (30%), Positives = 36/71 (50%), Gaps = 2/71 (2%)

Query: 120 EEDAESEDEEEEDVKLLSISGKRSAPGGGSKVPQKKVKLAADEDDDDDDEEDDDEDDDDD 179
           EE+ E E+EEE + +     G+     GG      + +   +E D D DEE  +E+D++ 
Sbjct: 409 EEEEEEEEEEEGEGEEEEEEGEEEEEEGGEGEELGEEEEVEEEGDVDSDEE--EEEDEES 466

Query: 180 DFDDEEAEEKA 190
             +  EAE+ A
Sbjct: 467 SSEGLEAEDWA 477



 Score = 32.0 bits (71), Expect = 0.55
 Identities = 12/48 (25%), Positives = 30/48 (62%)

Query: 142 RSAPGGGSKVPQKKVKLAADEDDDDDDEEDDDEDDDDDDFDDEEAEEK 189
           R A  GG         L ++ ++++++EE+++E++ + + ++EE EE+
Sbjct: 385 REAGFGGGPNATITTSLKSEGEEEEEEEEEEEEEEGEGEEEEEEGEEE 432



 Score = 30.8 bits (68), Expect = 1.2
 Identities = 24/111 (21%), Positives = 51/111 (45%), Gaps = 26/111 (23%)

Query: 105 GSGPVHISGQHLVAVEEDAESEDEEEEDVKLLSISGKRSAPGGGSKVPQKKVKLAADEDD 164
           G GP       L +  E+ E E+EEEE+ +           G G            +E++
Sbjct: 390 GGGPNATITTSLKSEGEEEEEEEEEEEEEE-----------GEG------------EEEE 426

Query: 165 DDDDEEDDDEDDDDDDFDDEEAEEKAPVKKSIRDTPAKNAQKSNQNGKDSK 215
           ++ +EE+++  + ++  ++EE EE+  V     D   +  ++S+  G +++
Sbjct: 427 EEGEEEEEEGGEGEELGEEEEVEEEGDVDS---DEEEEEDEESSSEGLEAE 474



 Score = 28.9 bits (63), Expect = 4.7
 Identities = 10/67 (14%), Positives = 37/67 (55%)

Query: 161 DEDDDDDDEEDDDEDDDDDDFDDEEAEEKAPVKKSIRDTPAKNAQKSNQNGKDSKPSSTP 220
           +E++++++EE+++ + ++++ + EE EE+    + + +      +    + ++ +     
Sbjct: 407 EEEEEEEEEEEEEGEGEEEEEEGEEEEEEGGEGEELGEEEEVEEEGDVDSDEEEEEDEES 466

Query: 221 RSKGQES 227
            S+G E+
Sbjct: 467 SSEGLEA 473


>gi|18093112 ABT1-associated protein [Homo sapiens]
          Length = 851

 Score = 48.1 bits (113), Expect = 7e-06
 Identities = 31/87 (35%), Positives = 47/87 (54%), Gaps = 15/87 (17%)

Query: 118 AVEEDAESEDE---EEEDVKLLSISGKRSAPGGGSKVPQKKVKLAADEDDDDDDEEDDDE 174
           A+EED+ES  E   +EE    ++  G+ S    GS+          DE++D+D+EED+DE
Sbjct: 238 ALEEDSESVSEIGSDEESENEITSVGRASGDDDGSE---------DDEEEDEDEEEDEDE 288

Query: 175 DDDDDDFDD---EEAEEKAPVKKSIRD 198
           D +DDD  D   + A  K  ++ S  D
Sbjct: 289 DSEDDDKSDSGPDLARGKGNIETSSED 315



 Score = 36.6 bits (83), Expect = 0.022
 Identities = 25/103 (24%), Positives = 42/103 (40%), Gaps = 1/103 (0%)

Query: 125 SEDEEEEDVKLLSISGKRSAPGGGSKVPQKKVKLAADEDDDDDDEEDDDEDDDDDDFDDE 184
           S D E  D   L    +  +  G  +  + ++        DDD  EDD+E+D+D++ D++
Sbjct: 228 STDGEMCDKDALEEDSESVSEIGSDEESENEITSVGRASGDDDGSEDDEEEDEDEEEDED 287

Query: 185 EAEEKAPVKKSIRD-TPAKNAQKSNQNGKDSKPSSTPRSKGQE 226
           E  E      S  D    K   +++   +D      P   G E
Sbjct: 288 EDSEDDDKSDSGPDLARGKGNIETSSEDEDDTADLFPEESGFE 330


>gi|51477718 TATA box binding protein-associated factor, RNA
           polymerase II, Q [Homo sapiens]
          Length = 462

 Score = 47.8 bits (112), Expect = 1e-05
 Identities = 27/99 (27%), Positives = 52/99 (52%)

Query: 161 DEDDDDDDEEDDDEDDDDDDFDDEEAEEKAPVKKSIRDTPAKNAQKSNQNGKDSKPSSTP 220
           ++DD+D+D+ED+DED+D+D+ +D+E EE+   ++ +         +S Q   +   SS  
Sbjct: 332 NDDDEDEDDEDEDEDEDEDEDEDKEEEEEDCSEEYLERQLQAEFIESGQYRANEGTSSIV 391

Query: 221 RSKGQESFKKQEKTPKTPKGPSSVEDIKAKMQASIEKAH 259
               ++  KK++K  K        +D+  K++    K H
Sbjct: 392 MEIQKQIEKKEKKLHKIQNKAQRQKDLIMKVENLTLKNH 430


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.304    0.126    0.344 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 11,686,948
Number of Sequences: 37866
Number of extensions: 646112
Number of successful extensions: 19404
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 641
Number of HSP's successfully gapped in prelim test: 472
Number of HSP's that attempted gapping in prelim test: 5459
Number of HSP's gapped (non-prelim): 5511
length of query: 259
length of database: 18,247,518
effective HSP length: 100
effective length of query: 159
effective length of database: 14,460,918
effective search space: 2299285962
effective search space used: 2299285962
T: 11
A: 40
X1: 16 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 43 (21.8 bits)
S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.