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Search of human proteins with 82830424
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|82830424 gon-4-like isoform a [Homo sapiens]
(2240 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|82830424 gon-4-like isoform a [Homo sapiens] 4496 0.0
gi|82830428 gon-4-like isoform b [Homo sapiens] 2989 0.0
gi|20986490 YY1-associated protein isoform 3 [Homo sapiens] 1400 0.0
gi|20986488 YY1-associated protein isoform 2 [Homo sapiens] 1362 0.0
gi|117414137 retinitis pigmentosa 1-like 1 [Homo sapiens] 72 6e-12
gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Hom... 71 1e-11
gi|146219843 Snf2-related CBP activator protein [Homo sapiens] 71 1e-11
gi|55956788 nucleolin [Homo sapiens] 65 7e-10
gi|115648142 centrosomal protein 164kDa [Homo sapiens] 62 6e-09
gi|212549782 caspase 8 associated protein 2 [Homo sapiens] 62 8e-09
gi|6912288 caspase 8 associated protein 2 [Homo sapiens] 62 8e-09
gi|212549532 caspase 8 associated protein 2 [Homo sapiens] 62 8e-09
gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens] 60 3e-08
gi|94536805 splicing factor YT521-B isoform 2 [Homo sapiens] 60 3e-08
gi|72534750 splicing factor YT521-B isoform 1 [Homo sapiens] 60 3e-08
gi|157738649 neurofilament, medium polypeptide 150kDa isoform 1 ... 58 9e-08
gi|157738641 neurofilament, medium polypeptide 150kDa isoform 2 ... 58 9e-08
gi|155030232 proline, glutamic acid and leucine rich protein 1 [... 57 2e-07
gi|58761548 tau tubulin kinase 1 [Homo sapiens] 57 2e-07
gi|210032580 SET domain containing 1B [Homo sapiens] 57 2e-07
gi|218505787 protocadherin 15 isoform CD2-1 precursor [Homo sapi... 56 3e-07
gi|153945728 microtubule-associated protein 1B [Homo sapiens] 56 3e-07
gi|55769548 PHD finger protein 14 isoform 2 [Homo sapiens] 55 6e-07
gi|55769550 PHD finger protein 14 isoform 1 [Homo sapiens] 55 6e-07
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 55 8e-07
gi|84043963 eukaryotic translation initiation factor 5B [Homo sa... 55 8e-07
gi|157738619 smoothelin-like 1 [Homo sapiens] 55 8e-07
gi|132626688 mediator of DNA-damage checkpoint 1 [Homo sapiens] 55 1e-06
gi|17975763 myelin transcription factor 1 [Homo sapiens] 54 1e-06
gi|16445033 ACRC protein [Homo sapiens] 54 1e-06
>gi|82830424 gon-4-like isoform a [Homo sapiens]
Length = 2240
Score = 4496 bits (11661), Expect = 0.0
Identities = 2240/2240 (100%), Positives = 2240/2240 (100%)
Query: 1 MLPCKKRRTTVTESLQHKGNQEENNVDLESAVKPESDQVKDLSSVSLSWDPSHGRVAGFE 60
MLPCKKRRTTVTESLQHKGNQEENNVDLESAVKPESDQVKDLSSVSLSWDPSHGRVAGFE
Sbjct: 1 MLPCKKRRTTVTESLQHKGNQEENNVDLESAVKPESDQVKDLSSVSLSWDPSHGRVAGFE 60
Query: 61 VQSLQDAGNQLGMEDTSLSSGMLTQNTNVPILEGVDVAISQGITLPSLESFHPLNIHIGK 120
VQSLQDAGNQLGMEDTSLSSGMLTQNTNVPILEGVDVAISQGITLPSLESFHPLNIHIGK
Sbjct: 61 VQSLQDAGNQLGMEDTSLSSGMLTQNTNVPILEGVDVAISQGITLPSLESFHPLNIHIGK 120
Query: 121 GKLHATGSKRGKKMTLRPGPVTQEDRCDHLTLKEPFSGEPSEEVKEEGGKPQMNSEGEIP 180
GKLHATGSKRGKKMTLRPGPVTQEDRCDHLTLKEPFSGEPSEEVKEEGGKPQMNSEGEIP
Sbjct: 121 GKLHATGSKRGKKMTLRPGPVTQEDRCDHLTLKEPFSGEPSEEVKEEGGKPQMNSEGEIP 180
Query: 181 SLPSGSQSAKPVSQPRKSTQPDVCASPQEKPLRTLFHQPEEEIEDGGLFIPMEEQDNEES 240
SLPSGSQSAKPVSQPRKSTQPDVCASPQEKPLRTLFHQPEEEIEDGGLFIPMEEQDNEES
Sbjct: 181 SLPSGSQSAKPVSQPRKSTQPDVCASPQEKPLRTLFHQPEEEIEDGGLFIPMEEQDNEES 240
Query: 241 EKRRKKKKGTKRKRDGRGQEGTLAYDLKLDDMLDRTLEDGAKQHNLTAVNVRNILHEVIT 300
EKRRKKKKGTKRKRDGRGQEGTLAYDLKLDDMLDRTLEDGAKQHNLTAVNVRNILHEVIT
Sbjct: 241 EKRRKKKKGTKRKRDGRGQEGTLAYDLKLDDMLDRTLEDGAKQHNLTAVNVRNILHEVIT 300
Query: 301 NEHVVAMMKAAISETEDMPMFEPKMTRSKLKEVVEKGVVIPTWNISPIKKANEIKPPQFV 360
NEHVVAMMKAAISETEDMPMFEPKMTRSKLKEVVEKGVVIPTWNISPIKKANEIKPPQFV
Sbjct: 301 NEHVVAMMKAAISETEDMPMFEPKMTRSKLKEVVEKGVVIPTWNISPIKKANEIKPPQFV 360
Query: 361 DIHLEEDDSSDEEYQPDDEEEDETAEESLLESDVESTASSPRGAKKSRLRQSSEMTETDE 420
DIHLEEDDSSDEEYQPDDEEEDETAEESLLESDVESTASSPRGAKKSRLRQSSEMTETDE
Sbjct: 361 DIHLEEDDSSDEEYQPDDEEEDETAEESLLESDVESTASSPRGAKKSRLRQSSEMTETDE 420
Query: 421 ESGILSEAEKVTTPAIRHISAEVVPMGPPPPPKPKQTRDSTFMEKLHAVDEELASSPVCM 480
ESGILSEAEKVTTPAIRHISAEVVPMGPPPPPKPKQTRDSTFMEKLHAVDEELASSPVCM
Sbjct: 421 ESGILSEAEKVTTPAIRHISAEVVPMGPPPPPKPKQTRDSTFMEKLHAVDEELASSPVCM 480
Query: 481 DSFQPMDDSLIAFRTRSKMPLKDVPLGQLEAELQAPDITPDMYDPNTADDEDWKMWLGGL 540
DSFQPMDDSLIAFRTRSKMPLKDVPLGQLEAELQAPDITPDMYDPNTADDEDWKMWLGGL
Sbjct: 481 DSFQPMDDSLIAFRTRSKMPLKDVPLGQLEAELQAPDITPDMYDPNTADDEDWKMWLGGL 540
Query: 541 MNDDVGNEDEADDDDDPEYNFLEDLDEPDTEDFRTDRAVRITKKEVNELMEELFETFQDE 600
MNDDVGNEDEADDDDDPEYNFLEDLDEPDTEDFRTDRAVRITKKEVNELMEELFETFQDE
Sbjct: 541 MNDDVGNEDEADDDDDPEYNFLEDLDEPDTEDFRTDRAVRITKKEVNELMEELFETFQDE 600
Query: 601 MGFSNMEDDGPEEEECVAEPRPNFNTPQALRFEEPLANLLNEQHRTVKELFEQLKMKKSS 660
MGFSNMEDDGPEEEECVAEPRPNFNTPQALRFEEPLANLLNEQHRTVKELFEQLKMKKSS
Sbjct: 601 MGFSNMEDDGPEEEECVAEPRPNFNTPQALRFEEPLANLLNEQHRTVKELFEQLKMKKSS 660
Query: 661 AKQLQEVEKVKPQSEKVHQTLILDPAQRKRLQQQMQQHVQLLTQIHLLATCNPNLNPEAT 720
AKQLQEVEKVKPQSEKVHQTLILDPAQRKRLQQQMQQHVQLLTQIHLLATCNPNLNPEAT
Sbjct: 661 AKQLQEVEKVKPQSEKVHQTLILDPAQRKRLQQQMQQHVQLLTQIHLLATCNPNLNPEAT 720
Query: 721 TTRIFLKELGTFAQSSIALHHQYNPKFQTLFQPCNLMGAMQLIEDFSTHVSIDCSPHKTV 780
TTRIFLKELGTFAQSSIALHHQYNPKFQTLFQPCNLMGAMQLIEDFSTHVSIDCSPHKTV
Sbjct: 721 TTRIFLKELGTFAQSSIALHHQYNPKFQTLFQPCNLMGAMQLIEDFSTHVSIDCSPHKTV 780
Query: 781 KKTANEFPCLPKQVAWILATSKVFMYPELLPVCSLKAKNPQDKIVFTKAEDNLLALGLKH 840
KKTANEFPCLPKQVAWILATSKVFMYPELLPVCSLKAKNPQDKIVFTKAEDNLLALGLKH
Sbjct: 781 KKTANEFPCLPKQVAWILATSKVFMYPELLPVCSLKAKNPQDKIVFTKAEDNLLALGLKH 840
Query: 841 FEGTEFPNPLISKYLLTCKTAHQLTVRIKNLNMNRAPDNIIKFYKKTKQLPVLGKCCEEI 900
FEGTEFPNPLISKYLLTCKTAHQLTVRIKNLNMNRAPDNIIKFYKKTKQLPVLGKCCEEI
Sbjct: 841 FEGTEFPNPLISKYLLTCKTAHQLTVRIKNLNMNRAPDNIIKFYKKTKQLPVLGKCCEEI 900
Query: 901 QPHQWKPPIEREEHRLPFWLKASLPSIQEELRHMADGAREVGNMTGTTEINSDRSLEKDN 960
QPHQWKPPIEREEHRLPFWLKASLPSIQEELRHMADGAREVGNMTGTTEINSDRSLEKDN
Sbjct: 901 QPHQWKPPIEREEHRLPFWLKASLPSIQEELRHMADGAREVGNMTGTTEINSDRSLEKDN 960
Query: 961 LELGSESRYPLLLPKGVVLKLKPVATRFPRKAWRQKRSSVLKPLLIQPSPSLQPSFNPGK 1020
LELGSESRYPLLLPKGVVLKLKPVATRFPRKAWRQKRSSVLKPLLIQPSPSLQPSFNPGK
Sbjct: 961 LELGSESRYPLLLPKGVVLKLKPVATRFPRKAWRQKRSSVLKPLLIQPSPSLQPSFNPGK 1020
Query: 1021 TPARSTHSEAPPSKMVLRIPHPIQPATVLQTVPGVPPLGVSGGESFESPAALPAVPPEAR 1080
TPARSTHSEAPPSKMVLRIPHPIQPATVLQTVPGVPPLGVSGGESFESPAALPAVPPEAR
Sbjct: 1021 TPARSTHSEAPPSKMVLRIPHPIQPATVLQTVPGVPPLGVSGGESFESPAALPAVPPEAR 1080
Query: 1081 TSFPLSESQTLLSSAPVPKVMLPSLAPSKFRKPYVRRRPSKRRGVKASPCMKPAPVIHHP 1140
TSFPLSESQTLLSSAPVPKVMLPSLAPSKFRKPYVRRRPSKRRGVKASPCMKPAPVIHHP
Sbjct: 1081 TSFPLSESQTLLSSAPVPKVMLPSLAPSKFRKPYVRRRPSKRRGVKASPCMKPAPVIHHP 1140
Query: 1141 ASVIFTVPATTVKIVSLGGGCNMIQPVNAAVAQSPQTIPITTLLVNPTSFPCPLNQSLVA 1200
ASVIFTVPATTVKIVSLGGGCNMIQPVNAAVAQSPQTIPITTLLVNPTSFPCPLNQSLVA
Sbjct: 1141 ASVIFTVPATTVKIVSLGGGCNMIQPVNAAVAQSPQTIPITTLLVNPTSFPCPLNQSLVA 1200
Query: 1201 SSVSPLIVSGNSVNLPIPSTPEDKAHVNVDIACAVADGENAFQGLEPKLEPQELSPLSAT 1260
SSVSPLIVSGNSVNLPIPSTPEDKAHVNVDIACAVADGENAFQGLEPKLEPQELSPLSAT
Sbjct: 1201 SSVSPLIVSGNSVNLPIPSTPEDKAHVNVDIACAVADGENAFQGLEPKLEPQELSPLSAT 1260
Query: 1261 VFPKVEHSPGPPLADAECQEGLSENSACRWTVVKTEEGRQALEPLPQGIQESLNNPTPGD 1320
VFPKVEHSPGPPLADAECQEGLSENSACRWTVVKTEEGRQALEPLPQGIQESLNNPTPGD
Sbjct: 1261 VFPKVEHSPGPPLADAECQEGLSENSACRWTVVKTEEGRQALEPLPQGIQESLNNPTPGD 1320
Query: 1321 LEEIVKMEPEEAREEISGSPERDICDDIKVEHAVELDTGAPSEELSSAGEVTKQTVLQKE 1380
LEEIVKMEPEEAREEISGSPERDICDDIKVEHAVELDTGAPSEELSSAGEVTKQTVLQKE
Sbjct: 1321 LEEIVKMEPEEAREEISGSPERDICDDIKVEHAVELDTGAPSEELSSAGEVTKQTVLQKE 1380
Query: 1381 EERSQPTKTPSSSQEPPDEGTSGTDVNKGSSKNALSSMDPEVRLSSPPGKPEDSSSVDGQ 1440
EERSQPTKTPSSSQEPPDEGTSGTDVNKGSSKNALSSMDPEVRLSSPPGKPEDSSSVDGQ
Sbjct: 1381 EERSQPTKTPSSSQEPPDEGTSGTDVNKGSSKNALSSMDPEVRLSSPPGKPEDSSSVDGQ 1440
Query: 1441 SVGTPVGPETGGEKNGPEEEEEEDFDDLTQDEEDEMSSASEESVLSVPELQETMEKLTWL 1500
SVGTPVGPETGGEKNGPEEEEEEDFDDLTQDEEDEMSSASEESVLSVPELQETMEKLTWL
Sbjct: 1441 SVGTPVGPETGGEKNGPEEEEEEDFDDLTQDEEDEMSSASEESVLSVPELQETMEKLTWL 1500
Query: 1501 ASERRMSQEGESEEENSQEENSEPEEEEEEEAEGMESLQKEDEMTDEAVGDSAEKPPTFA 1560
ASERRMSQEGESEEENSQEENSEPEEEEEEEAEGMESLQKEDEMTDEAVGDSAEKPPTFA
Sbjct: 1501 ASERRMSQEGESEEENSQEENSEPEEEEEEEAEGMESLQKEDEMTDEAVGDSAEKPPTFA 1560
Query: 1561 SPETAPEVETSRTPPGESIKAAGKGRNNHRARNKRGSRARASKDTSKLLLLYDEDILERD 1620
SPETAPEVETSRTPPGESIKAAGKGRNNHRARNKRGSRARASKDTSKLLLLYDEDILERD
Sbjct: 1561 SPETAPEVETSRTPPGESIKAAGKGRNNHRARNKRGSRARASKDTSKLLLLYDEDILERD 1620
Query: 1621 PLREQKDLAFAQAYLTRVREALQHIPGKYEDFLQVIYEFESSTQRRTAVDLYKSLQILLQ 1680
PLREQKDLAFAQAYLTRVREALQHIPGKYEDFLQVIYEFESSTQRRTAVDLYKSLQILLQ
Sbjct: 1621 PLREQKDLAFAQAYLTRVREALQHIPGKYEDFLQVIYEFESSTQRRTAVDLYKSLQILLQ 1680
Query: 1681 DWPQLLKDFAAFLLPEQALACGLFEEQQAFEKSRKFLRQLEICFAENPSHHQKIIKVLQG 1740
DWPQLLKDFAAFLLPEQALACGLFEEQQAFEKSRKFLRQLEICFAENPSHHQKIIKVLQG
Sbjct: 1681 DWPQLLKDFAAFLLPEQALACGLFEEQQAFEKSRKFLRQLEICFAENPSHHQKIIKVLQG 1740
Query: 1741 CADCLPQEITELKTQMWQLLKGHDHLQDEFSIFFDHLRPAASRMGDFEEINWTEEKEYEF 1800
CADCLPQEITELKTQMWQLLKGHDHLQDEFSIFFDHLRPAASRMGDFEEINWTEEKEYEF
Sbjct: 1741 CADCLPQEITELKTQMWQLLKGHDHLQDEFSIFFDHLRPAASRMGDFEEINWTEEKEYEF 1800
Query: 1801 DGFEEVALPDVEEEEEPPKIPTASKNKRKKEIGVQNHDKETEWPDGAKDCACSCHEGGPD 1860
DGFEEVALPDVEEEEEPPKIPTASKNKRKKEIGVQNHDKETEWPDGAKDCACSCHEGGPD
Sbjct: 1801 DGFEEVALPDVEEEEEPPKIPTASKNKRKKEIGVQNHDKETEWPDGAKDCACSCHEGGPD 1860
Query: 1861 SKLKKSKRRSCSHCSSKVCDSKSYKSKEPHELVGSSPHREASPMPGAKEAGQGKDMMEEE 1920
SKLKKSKRRSCSHCSSKVCDSKSYKSKEPHELVGSSPHREASPMPGAKEAGQGKDMMEEE
Sbjct: 1861 SKLKKSKRRSCSHCSSKVCDSKSYKSKEPHELVGSSPHREASPMPGAKEAGQGKDMMEEE 1920
Query: 1921 APEERESTEATQSRTVRTTRKGEMPVSGLAVGSTLPSPREVTVTERLLLDGPPPHSPETP 1980
APEERESTEATQSRTVRTTRKGEMPVSGLAVGSTLPSPREVTVTERLLLDGPPPHSPETP
Sbjct: 1921 APEERESTEATQSRTVRTTRKGEMPVSGLAVGSTLPSPREVTVTERLLLDGPPPHSPETP 1980
Query: 1981 QFPPTTGAVLYTVKRNQVGPEVRSCPKASPRLQKEREGQKAVSESEALMLVWDASETEKL 2040
QFPPTTGAVLYTVKRNQVGPEVRSCPKASPRLQKEREGQKAVSESEALMLVWDASETEKL
Sbjct: 1981 QFPPTTGAVLYTVKRNQVGPEVRSCPKASPRLQKEREGQKAVSESEALMLVWDASETEKL 2040
Query: 2041 PGTVEPPASFLSPVSSKTRDAGRRHVSGKPDTQERWLPSSRARVKTRDRTCPVHESPSGI 2100
PGTVEPPASFLSPVSSKTRDAGRRHVSGKPDTQERWLPSSRARVKTRDRTCPVHESPSGI
Sbjct: 2041 PGTVEPPASFLSPVSSKTRDAGRRHVSGKPDTQERWLPSSRARVKTRDRTCPVHESPSGI 2100
Query: 2101 DTSETSPKAPRGGLAKDSGTQAKGPEGEQQPKAAEATVCANNSKVSSTGEKVVLWTREAD 2160
DTSETSPKAPRGGLAKDSGTQAKGPEGEQQPKAAEATVCANNSKVSSTGEKVVLWTREAD
Sbjct: 2101 DTSETSPKAPRGGLAKDSGTQAKGPEGEQQPKAAEATVCANNSKVSSTGEKVVLWTREAD 2160
Query: 2161 RVILTMCQEQGAQPQTFNIISQQLGNKTPAEVSHRFRELMQLFHTACEASSEDEDDATST 2220
RVILTMCQEQGAQPQTFNIISQQLGNKTPAEVSHRFRELMQLFHTACEASSEDEDDATST
Sbjct: 2161 RVILTMCQEQGAQPQTFNIISQQLGNKTPAEVSHRFRELMQLFHTACEASSEDEDDATST 2220
Query: 2221 SNADQLSDHGDLLSEEELDE 2240
SNADQLSDHGDLLSEEELDE
Sbjct: 2221 SNADQLSDHGDLLSEEELDE 2240
>gi|82830428 gon-4-like isoform b [Homo sapiens]
Length = 1529
Score = 2989 bits (7749), Expect = 0.0
Identities = 1491/1491 (100%), Positives = 1491/1491 (100%)
Query: 1 MLPCKKRRTTVTESLQHKGNQEENNVDLESAVKPESDQVKDLSSVSLSWDPSHGRVAGFE 60
MLPCKKRRTTVTESLQHKGNQEENNVDLESAVKPESDQVKDLSSVSLSWDPSHGRVAGFE
Sbjct: 1 MLPCKKRRTTVTESLQHKGNQEENNVDLESAVKPESDQVKDLSSVSLSWDPSHGRVAGFE 60
Query: 61 VQSLQDAGNQLGMEDTSLSSGMLTQNTNVPILEGVDVAISQGITLPSLESFHPLNIHIGK 120
VQSLQDAGNQLGMEDTSLSSGMLTQNTNVPILEGVDVAISQGITLPSLESFHPLNIHIGK
Sbjct: 61 VQSLQDAGNQLGMEDTSLSSGMLTQNTNVPILEGVDVAISQGITLPSLESFHPLNIHIGK 120
Query: 121 GKLHATGSKRGKKMTLRPGPVTQEDRCDHLTLKEPFSGEPSEEVKEEGGKPQMNSEGEIP 180
GKLHATGSKRGKKMTLRPGPVTQEDRCDHLTLKEPFSGEPSEEVKEEGGKPQMNSEGEIP
Sbjct: 121 GKLHATGSKRGKKMTLRPGPVTQEDRCDHLTLKEPFSGEPSEEVKEEGGKPQMNSEGEIP 180
Query: 181 SLPSGSQSAKPVSQPRKSTQPDVCASPQEKPLRTLFHQPEEEIEDGGLFIPMEEQDNEES 240
SLPSGSQSAKPVSQPRKSTQPDVCASPQEKPLRTLFHQPEEEIEDGGLFIPMEEQDNEES
Sbjct: 181 SLPSGSQSAKPVSQPRKSTQPDVCASPQEKPLRTLFHQPEEEIEDGGLFIPMEEQDNEES 240
Query: 241 EKRRKKKKGTKRKRDGRGQEGTLAYDLKLDDMLDRTLEDGAKQHNLTAVNVRNILHEVIT 300
EKRRKKKKGTKRKRDGRGQEGTLAYDLKLDDMLDRTLEDGAKQHNLTAVNVRNILHEVIT
Sbjct: 241 EKRRKKKKGTKRKRDGRGQEGTLAYDLKLDDMLDRTLEDGAKQHNLTAVNVRNILHEVIT 300
Query: 301 NEHVVAMMKAAISETEDMPMFEPKMTRSKLKEVVEKGVVIPTWNISPIKKANEIKPPQFV 360
NEHVVAMMKAAISETEDMPMFEPKMTRSKLKEVVEKGVVIPTWNISPIKKANEIKPPQFV
Sbjct: 301 NEHVVAMMKAAISETEDMPMFEPKMTRSKLKEVVEKGVVIPTWNISPIKKANEIKPPQFV 360
Query: 361 DIHLEEDDSSDEEYQPDDEEEDETAEESLLESDVESTASSPRGAKKSRLRQSSEMTETDE 420
DIHLEEDDSSDEEYQPDDEEEDETAEESLLESDVESTASSPRGAKKSRLRQSSEMTETDE
Sbjct: 361 DIHLEEDDSSDEEYQPDDEEEDETAEESLLESDVESTASSPRGAKKSRLRQSSEMTETDE 420
Query: 421 ESGILSEAEKVTTPAIRHISAEVVPMGPPPPPKPKQTRDSTFMEKLHAVDEELASSPVCM 480
ESGILSEAEKVTTPAIRHISAEVVPMGPPPPPKPKQTRDSTFMEKLHAVDEELASSPVCM
Sbjct: 421 ESGILSEAEKVTTPAIRHISAEVVPMGPPPPPKPKQTRDSTFMEKLHAVDEELASSPVCM 480
Query: 481 DSFQPMDDSLIAFRTRSKMPLKDVPLGQLEAELQAPDITPDMYDPNTADDEDWKMWLGGL 540
DSFQPMDDSLIAFRTRSKMPLKDVPLGQLEAELQAPDITPDMYDPNTADDEDWKMWLGGL
Sbjct: 481 DSFQPMDDSLIAFRTRSKMPLKDVPLGQLEAELQAPDITPDMYDPNTADDEDWKMWLGGL 540
Query: 541 MNDDVGNEDEADDDDDPEYNFLEDLDEPDTEDFRTDRAVRITKKEVNELMEELFETFQDE 600
MNDDVGNEDEADDDDDPEYNFLEDLDEPDTEDFRTDRAVRITKKEVNELMEELFETFQDE
Sbjct: 541 MNDDVGNEDEADDDDDPEYNFLEDLDEPDTEDFRTDRAVRITKKEVNELMEELFETFQDE 600
Query: 601 MGFSNMEDDGPEEEECVAEPRPNFNTPQALRFEEPLANLLNEQHRTVKELFEQLKMKKSS 660
MGFSNMEDDGPEEEECVAEPRPNFNTPQALRFEEPLANLLNEQHRTVKELFEQLKMKKSS
Sbjct: 601 MGFSNMEDDGPEEEECVAEPRPNFNTPQALRFEEPLANLLNEQHRTVKELFEQLKMKKSS 660
Query: 661 AKQLQEVEKVKPQSEKVHQTLILDPAQRKRLQQQMQQHVQLLTQIHLLATCNPNLNPEAT 720
AKQLQEVEKVKPQSEKVHQTLILDPAQRKRLQQQMQQHVQLLTQIHLLATCNPNLNPEAT
Sbjct: 661 AKQLQEVEKVKPQSEKVHQTLILDPAQRKRLQQQMQQHVQLLTQIHLLATCNPNLNPEAT 720
Query: 721 TTRIFLKELGTFAQSSIALHHQYNPKFQTLFQPCNLMGAMQLIEDFSTHVSIDCSPHKTV 780
TTRIFLKELGTFAQSSIALHHQYNPKFQTLFQPCNLMGAMQLIEDFSTHVSIDCSPHKTV
Sbjct: 721 TTRIFLKELGTFAQSSIALHHQYNPKFQTLFQPCNLMGAMQLIEDFSTHVSIDCSPHKTV 780
Query: 781 KKTANEFPCLPKQVAWILATSKVFMYPELLPVCSLKAKNPQDKIVFTKAEDNLLALGLKH 840
KKTANEFPCLPKQVAWILATSKVFMYPELLPVCSLKAKNPQDKIVFTKAEDNLLALGLKH
Sbjct: 781 KKTANEFPCLPKQVAWILATSKVFMYPELLPVCSLKAKNPQDKIVFTKAEDNLLALGLKH 840
Query: 841 FEGTEFPNPLISKYLLTCKTAHQLTVRIKNLNMNRAPDNIIKFYKKTKQLPVLGKCCEEI 900
FEGTEFPNPLISKYLLTCKTAHQLTVRIKNLNMNRAPDNIIKFYKKTKQLPVLGKCCEEI
Sbjct: 841 FEGTEFPNPLISKYLLTCKTAHQLTVRIKNLNMNRAPDNIIKFYKKTKQLPVLGKCCEEI 900
Query: 901 QPHQWKPPIEREEHRLPFWLKASLPSIQEELRHMADGAREVGNMTGTTEINSDRSLEKDN 960
QPHQWKPPIEREEHRLPFWLKASLPSIQEELRHMADGAREVGNMTGTTEINSDRSLEKDN
Sbjct: 901 QPHQWKPPIEREEHRLPFWLKASLPSIQEELRHMADGAREVGNMTGTTEINSDRSLEKDN 960
Query: 961 LELGSESRYPLLLPKGVVLKLKPVATRFPRKAWRQKRSSVLKPLLIQPSPSLQPSFNPGK 1020
LELGSESRYPLLLPKGVVLKLKPVATRFPRKAWRQKRSSVLKPLLIQPSPSLQPSFNPGK
Sbjct: 961 LELGSESRYPLLLPKGVVLKLKPVATRFPRKAWRQKRSSVLKPLLIQPSPSLQPSFNPGK 1020
Query: 1021 TPARSTHSEAPPSKMVLRIPHPIQPATVLQTVPGVPPLGVSGGESFESPAALPAVPPEAR 1080
TPARSTHSEAPPSKMVLRIPHPIQPATVLQTVPGVPPLGVSGGESFESPAALPAVPPEAR
Sbjct: 1021 TPARSTHSEAPPSKMVLRIPHPIQPATVLQTVPGVPPLGVSGGESFESPAALPAVPPEAR 1080
Query: 1081 TSFPLSESQTLLSSAPVPKVMLPSLAPSKFRKPYVRRRPSKRRGVKASPCMKPAPVIHHP 1140
TSFPLSESQTLLSSAPVPKVMLPSLAPSKFRKPYVRRRPSKRRGVKASPCMKPAPVIHHP
Sbjct: 1081 TSFPLSESQTLLSSAPVPKVMLPSLAPSKFRKPYVRRRPSKRRGVKASPCMKPAPVIHHP 1140
Query: 1141 ASVIFTVPATTVKIVSLGGGCNMIQPVNAAVAQSPQTIPITTLLVNPTSFPCPLNQSLVA 1200
ASVIFTVPATTVKIVSLGGGCNMIQPVNAAVAQSPQTIPITTLLVNPTSFPCPLNQSLVA
Sbjct: 1141 ASVIFTVPATTVKIVSLGGGCNMIQPVNAAVAQSPQTIPITTLLVNPTSFPCPLNQSLVA 1200
Query: 1201 SSVSPLIVSGNSVNLPIPSTPEDKAHVNVDIACAVADGENAFQGLEPKLEPQELSPLSAT 1260
SSVSPLIVSGNSVNLPIPSTPEDKAHVNVDIACAVADGENAFQGLEPKLEPQELSPLSAT
Sbjct: 1201 SSVSPLIVSGNSVNLPIPSTPEDKAHVNVDIACAVADGENAFQGLEPKLEPQELSPLSAT 1260
Query: 1261 VFPKVEHSPGPPLADAECQEGLSENSACRWTVVKTEEGRQALEPLPQGIQESLNNPTPGD 1320
VFPKVEHSPGPPLADAECQEGLSENSACRWTVVKTEEGRQALEPLPQGIQESLNNPTPGD
Sbjct: 1261 VFPKVEHSPGPPLADAECQEGLSENSACRWTVVKTEEGRQALEPLPQGIQESLNNPTPGD 1320
Query: 1321 LEEIVKMEPEEAREEISGSPERDICDDIKVEHAVELDTGAPSEELSSAGEVTKQTVLQKE 1380
LEEIVKMEPEEAREEISGSPERDICDDIKVEHAVELDTGAPSEELSSAGEVTKQTVLQKE
Sbjct: 1321 LEEIVKMEPEEAREEISGSPERDICDDIKVEHAVELDTGAPSEELSSAGEVTKQTVLQKE 1380
Query: 1381 EERSQPTKTPSSSQEPPDEGTSGTDVNKGSSKNALSSMDPEVRLSSPPGKPEDSSSVDGQ 1440
EERSQPTKTPSSSQEPPDEGTSGTDVNKGSSKNALSSMDPEVRLSSPPGKPEDSSSVDGQ
Sbjct: 1381 EERSQPTKTPSSSQEPPDEGTSGTDVNKGSSKNALSSMDPEVRLSSPPGKPEDSSSVDGQ 1440
Query: 1441 SVGTPVGPETGGEKNGPEEEEEEDFDDLTQDEEDEMSSASEESVLSVPELQ 1491
SVGTPVGPETGGEKNGPEEEEEEDFDDLTQDEEDEMSSASEESVLSVPELQ
Sbjct: 1441 SVGTPVGPETGGEKNGPEEEEEEDFDDLTQDEEDEMSSASEESVLSVPELQ 1491
>gi|20986490 YY1-associated protein isoform 3 [Homo sapiens]
Length = 750
Score = 1400 bits (3625), Expect = 0.0
Identities = 698/749 (93%), Positives = 720/749 (96%), Gaps = 1/749 (0%)
Query: 590 MEELFETFQDEMGFSNMEDDGPEEEECVAEPRPNFNTPQALRFEEPLANLLNEQHRTVKE 649
ME+LFETFQDEMGFSNMEDDGPEEEE VAEP+ NFNTPQALRFEE LANLLNEQH+ KE
Sbjct: 1 MEDLFETFQDEMGFSNMEDDGPEEEERVAEPQANFNTPQALRFEELLANLLNEQHQIAKE 60
Query: 650 LFEQLKMKKSSAKQLQEVEKVKPQSEKVHQTLILDPAQRKRLQQQMQQHVQLLTQIHLLA 709
LFEQLKMKK SAKQ +EVEKVKPQ ++VHQTLILDPAQRKRLQQQMQQHVQLLTQIHLLA
Sbjct: 61 LFEQLKMKKPSAKQQKEVEKVKPQCKEVHQTLILDPAQRKRLQQQMQQHVQLLTQIHLLA 120
Query: 710 TCNPNLNPEATTTRIFLKELGTFAQSSIALHHQYNPKFQTLFQPCNLMGAMQLIEDFSTH 769
TCNPNLNPEA++TRI LKELGTFAQSSIALHHQYNPKFQTLFQPCNLMGAMQLIEDFSTH
Sbjct: 121 TCNPNLNPEASSTRICLKELGTFAQSSIALHHQYNPKFQTLFQPCNLMGAMQLIEDFSTH 180
Query: 770 VSIDCSPHKTVKKTANEFPCLPKQVAWILATSKVFMYPELLPVCSLKAKNPQDKIVFTKA 829
VSIDCSPHKTVKKTANEFPCLPKQVAWILATSKVFMYPELLPVCSLKAKNPQDKI+FTKA
Sbjct: 181 VSIDCSPHKTVKKTANEFPCLPKQVAWILATSKVFMYPELLPVCSLKAKNPQDKILFTKA 240
Query: 830 EDNLLALGLKHFEGTEFPNPLISKYLLTCKTAHQLTVRIKNLNMNRAPDNIIKFYKKTKQ 889
EDNLLALGLKHFEGTEF NPLISKYLLTCKTA QLTVRIKNLNMNRAPDNIIKFYKKTKQ
Sbjct: 241 EDNLLALGLKHFEGTEFLNPLISKYLLTCKTARQLTVRIKNLNMNRAPDNIIKFYKKTKQ 300
Query: 890 LPVLGKCCEEIQPHQWKPPIEREEHRLPFWLKASLPSIQEELRHMADGAREVGNMTGTTE 949
LPVLGKCCEEIQPHQWKPPIEREEHRLPFWLKASLPSIQEELRHMADGAREVGNMTGTTE
Sbjct: 301 LPVLGKCCEEIQPHQWKPPIEREEHRLPFWLKASLPSIQEELRHMADGAREVGNMTGTTE 360
Query: 950 INSDRSLEKDNLELGSESRYPLLLPKGVVLKLKPVATRFPRKAWRQKRSSVLKPLLIQPS 1009
INSD+ LEKDN ELGSE+RYPLLLPKGVVLKLKPVA RFP+KAWRQKRSSVLKPLLIQPS
Sbjct: 361 INSDQGLEKDNSELGSETRYPLLLPKGVVLKLKPVADRFPKKAWRQKRSSVLKPLLIQPS 420
Query: 1010 PSLQPSFNPGKTPARSTHSEAPPSKMVLRIPHPIQPATVLQTVPGVPPLGVSGGESFESP 1069
PSLQPSFNPGKTPA+STHSEAPPSKMVLRIPHPIQPATVLQTVPGVPPLGVSGGESFESP
Sbjct: 421 PSLQPSFNPGKTPAQSTHSEAPPSKMVLRIPHPIQPATVLQTVPGVPPLGVSGGESFESP 480
Query: 1070 AALPAVPPEARTSFPLSESQTLLSSAPVPKVMLPSLAPSKFRKPYVRRRPSKRRGVKASP 1129
AALPA+PPEARTSFPLSESQTLLSSAPVPKVM+PS A S FRKPYVRRRPSKRRG +A
Sbjct: 481 AALPAMPPEARTSFPLSESQTLLSSAPVPKVMMPSPASSMFRKPYVRRRPSKRRGARAFR 540
Query: 1130 CMKPAPVIHHPASVIFTVPATTVKIVSLGGGCNMIQPVNAAVAQSPQTIPITTLLVNPTS 1189
C+KPAPVI HPASVIFTVPATTVKIVSLGGGCNMIQPVNAAVAQSPQTIPI TLLVNPTS
Sbjct: 541 CIKPAPVI-HPASVIFTVPATTVKIVSLGGGCNMIQPVNAAVAQSPQTIPIATLLVNPTS 599
Query: 1190 FPCPLNQSLVASSVSPLIVSGNSVNLPIPSTPEDKAHVNVDIACAVADGENAFQGLEPKL 1249
FPCPLNQ LVASSVSPLIVSGNSVNLPIPSTPEDKAH+NVDIACAVADGENAFQGLEPKL
Sbjct: 600 FPCPLNQPLVASSVSPLIVSGNSVNLPIPSTPEDKAHMNVDIACAVADGENAFQGLEPKL 659
Query: 1250 EPQELSPLSATVFPKVEHSPGPPLADAECQEGLSENSACRWTVVKTEEGRQALEPLPQGI 1309
EPQELSPLSATVFPKVEHSPGPP D +CQEGLSENSA RWTVVKTEEGRQALEPLPQGI
Sbjct: 660 EPQELSPLSATVFPKVEHSPGPPPVDKQCQEGLSENSAYRWTVVKTEEGRQALEPLPQGI 719
Query: 1310 QESLNNPTPGDLEEIVKMEPEEAREEISG 1338
QESLNN +PGDLEE+VKMEPE+A EEISG
Sbjct: 720 QESLNNSSPGDLEEVVKMEPEDATEEISG 748
>gi|20986488 YY1-associated protein isoform 2 [Homo sapiens]
Length = 796
Score = 1362 bits (3526), Expect = 0.0
Identities = 684/756 (90%), Positives = 707/756 (93%), Gaps = 21/756 (2%)
Query: 583 KKEVNELMEELFETFQDEMGFSNMEDDGPEEEECVAEPRPNFNTPQALRFEEPLANLLNE 642
+KE NELME+LFETFQDEMGFSNMEDDGPEEEE VAEP+ NFNTPQALRFEE LANLLNE
Sbjct: 60 EKEANELMEDLFETFQDEMGFSNMEDDGPEEEERVAEPQANFNTPQALRFEELLANLLNE 119
Query: 643 QHRTVKELFEQLKMKKSSAKQLQEVEKVKPQSEKVHQTLILDPAQRKRLQQQMQQHVQLL 702
QH+ KELFEQLKMKK SAKQ +EVEKVKPQ ++VHQTLILDPAQRKRLQQQMQQHVQLL
Sbjct: 120 QHQIAKELFEQLKMKKPSAKQQKEVEKVKPQCKEVHQTLILDPAQRKRLQQQMQQHVQLL 179
Query: 703 TQIHLLATCNPNLNPEATTTRIFLKELGTFAQSSIALHHQYNPKFQTLFQPCNLMGAMQL 762
TQIHLLATCNPNLNPEA++TRI LKELGTFAQSSIALHHQYNPKFQTLFQPCNLMGAMQL
Sbjct: 180 TQIHLLATCNPNLNPEASSTRICLKELGTFAQSSIALHHQYNPKFQTLFQPCNLMGAMQL 239
Query: 763 IEDFSTHVSIDCSPHKTVKKTANEFPCLPKQVAWILATSKVFMYPELLPVCSLKAKNPQD 822
IEDFSTHVSIDCSPHKTVKKTANEFPCLPKQVAWILATSKVFMYPELLPVCSLKAKNPQD
Sbjct: 240 IEDFSTHVSIDCSPHKTVKKTANEFPCLPKQVAWILATSKVFMYPELLPVCSLKAKNPQD 299
Query: 823 KIVFTKAEDNLLALGLKHFEGTEFPNPLISKYLLTCKTAHQLTVRIKNLNMNRAPDNIIK 882
KI+FTKAEDN KYLLTCKTA QLTVRIKNLNMNRAPDNIIK
Sbjct: 300 KILFTKAEDN--------------------KYLLTCKTARQLTVRIKNLNMNRAPDNIIK 339
Query: 883 FYKKTKQLPVLGKCCEEIQPHQWKPPIEREEHRLPFWLKASLPSIQEELRHMADGAREVG 942
FYKKTKQLPVLGKCCEEIQPHQWKPPIEREEHRLPFWLKASLPSIQEELRHMADGAREVG
Sbjct: 340 FYKKTKQLPVLGKCCEEIQPHQWKPPIEREEHRLPFWLKASLPSIQEELRHMADGAREVG 399
Query: 943 NMTGTTEINSDRSLEKDNLELGSESRYPLLLPKGVVLKLKPVATRFPRKAWRQKRSSVLK 1002
NMTGTTEINSD+ LEKDN ELGSE+RYPLLLPKGVVLKLKPVA RFP+KAWRQKRSSVLK
Sbjct: 400 NMTGTTEINSDQGLEKDNSELGSETRYPLLLPKGVVLKLKPVADRFPKKAWRQKRSSVLK 459
Query: 1003 PLLIQPSPSLQPSFNPGKTPARSTHSEAPPSKMVLRIPHPIQPATVLQTVPGVPPLGVSG 1062
PLLIQPSPSLQPSFNPGKTPA+STHSEAPPSKMVLRIPHPIQPATVLQTVPGVPPLGVSG
Sbjct: 460 PLLIQPSPSLQPSFNPGKTPAQSTHSEAPPSKMVLRIPHPIQPATVLQTVPGVPPLGVSG 519
Query: 1063 GESFESPAALPAVPPEARTSFPLSESQTLLSSAPVPKVMLPSLAPSKFRKPYVRRRPSKR 1122
GESFESPAALPA+PPEARTSFPLSESQTLLSSAPVPKVM+PS A S FRKPYVRRRPSKR
Sbjct: 520 GESFESPAALPAMPPEARTSFPLSESQTLLSSAPVPKVMMPSPASSMFRKPYVRRRPSKR 579
Query: 1123 RGVKASPCMKPAPVIHHPASVIFTVPATTVKIVSLGGGCNMIQPVNAAVAQSPQTIPITT 1182
RG +A C+KPAPVI HPASVIFTVPATTVKIVSLGGGCNMIQPVNAAVAQSPQTIPI T
Sbjct: 580 RGARAFRCIKPAPVI-HPASVIFTVPATTVKIVSLGGGCNMIQPVNAAVAQSPQTIPIAT 638
Query: 1183 LLVNPTSFPCPLNQSLVASSVSPLIVSGNSVNLPIPSTPEDKAHVNVDIACAVADGENAF 1242
LLVNPTSFPCPLNQ LVASSVSPLIVSGNSVNLPIPSTPEDKAH+NVDIACAVADGENAF
Sbjct: 639 LLVNPTSFPCPLNQPLVASSVSPLIVSGNSVNLPIPSTPEDKAHMNVDIACAVADGENAF 698
Query: 1243 QGLEPKLEPQELSPLSATVFPKVEHSPGPPLADAECQEGLSENSACRWTVVKTEEGRQAL 1302
QGLEPKLEPQELSPLSATVFPKVEHSPGPP D +CQEGLSENSA RWTVVKTEEGRQAL
Sbjct: 699 QGLEPKLEPQELSPLSATVFPKVEHSPGPPPVDKQCQEGLSENSAYRWTVVKTEEGRQAL 758
Query: 1303 EPLPQGIQESLNNPTPGDLEEIVKMEPEEAREEISG 1338
EPLPQGIQESLNN +PGDLEE+VKMEPE+A EEISG
Sbjct: 759 EPLPQGIQESLNNSSPGDLEEVVKMEPEDATEEISG 794
>gi|117414137 retinitis pigmentosa 1-like 1 [Homo sapiens]
Length = 2400
Score = 72.0 bits (175), Expect = 6e-12
Identities = 92/375 (24%), Positives = 142/375 (37%), Gaps = 42/375 (11%)
Query: 1230 DIACAVADGENAFQGLEPKLEPQELSPLSATVFPKVEHSPGPPLADAECQEGLSENSACR 1289
D+ A+GE +P+ E E V P+ E + P A+ E Q A
Sbjct: 1873 DVEAPEAEGE-----AQPESEDVETPEAEWEVQPESEGAEAPE-AEKEAQPETESVEALE 1926
Query: 1290 WTVVKTE---EGRQALEPLPQGIQESLNNPTPGDLEEIVKMEPEEAREEISGSPERDICD 1346
T + E EG +A E + QE+ P E +E +EA EE PE + +
Sbjct: 1927 -TEGEDEPESEGAEAQEA-EEAAQEAEGQTQP----ESEVIESQEAEEE--AQPESEDVE 1978
Query: 1347 DIKVEHAVELDTGAPSEELSSAGEVTKQTVLQKEEERSQPTKTPSSSQEPPDEGTSGTDV 1406
++VE + G E + +Q+ EE +QP +Q P EG +V
Sbjct: 1979 ALEVEVETQEAEGEAQPESEDVEAPEAEGEMQEAEEEAQPESDGVEAQ-PKSEGEEAQEV 2037
Query: 1407 NKGSSKNALSSMDPEVRLSSPPGKPE-----------------DSSSVDGQSVGTPVGPE 1449
+ K + + +P + E +S VD Q PE
Sbjct: 2038 EGETQKTEGDAQPESDGVEAPEAEEEAQEAEGEVQEAEGEAHPESEDVDAQEAEGEAQPE 2097
Query: 1450 TGGEKNGPEEEEEEDFDDLTQDEEDEMSSASEESVLSVPELQETMEKLTWLASERRMSQE 1509
+ G + PE E E + + E E + E + PE + + + E
Sbjct: 2098 SEGVE-APEAEGEAQKAEGIEAPETEGEAQPESEGIEAPEAEGEAQPES--EGVEAQDAE 2154
Query: 1510 GESEEENSQEENSEPEEEEEEEAEGMESLQKEDEMTDEAVGDSAEKPPTFASPE----TA 1565
GE++ E+ E E EEE + E EG+E+ + E E E+ G A + A PE A
Sbjct: 2155 GEAQPESEGIEAQEAEEEAQPELEGVEAPEAEGEAQPESEGIEAPEAEGEAQPELEGVEA 2214
Query: 1566 PEVETSRTPPGESIK 1580
PE E P E ++
Sbjct: 2215 PEAEEEAQPEPEGVE 2229
Score = 60.1 bits (144), Expect = 2e-08
Identities = 73/349 (20%), Positives = 126/349 (36%), Gaps = 22/349 (6%)
Query: 1235 VADGENAFQGLEPKLEPQELSPLSATVFPKVEHSPGPPLADAECQEGLSENSACRWTVVK 1294
V + + A + +P+ E E + + E P D E E E
Sbjct: 1960 VIESQEAEEEAQPESEDVEALEVEVET-QEAEGEAQPESEDVEAPEAEGE---------- 2008
Query: 1295 TEEGRQALEPLPQGIQESLNNPTPGDLEEIVKMEPEEAREEISGSPERDICDDIKVEHAV 1354
+E + +P G++ + + EE ++E E + E PE D + + E
Sbjct: 2009 MQEAEEEAQPESDGVEAQPKS----EGEEAQEVEGETQKTEGDAQPESDGVEAPEAEEEA 2064
Query: 1355 ELDTGAPSEELSSAGEVTKQTVLQKEEERSQPTKTPSSSQEPPDEGTSGTDVNKGSSKNA 1414
+ G E A ++ Q+ E +QP + E E + ++
Sbjct: 2065 QEAEGEVQEAEGEAHPESEDVDAQEAEGEAQPESEGVEAPEAEGEAQKAEGIEAPETEGE 2124
Query: 1415 LSSMDPEVRLSSPPGKPE-DSSSVDGQSVGTPVGPETGG-EKNGPEEEEEEDFDDLTQDE 1472
+ G+ + +S V+ Q PE+ G E EEE + + + + E
Sbjct: 2125 AQPESEGIEAPEAEGEAQPESEGVEAQDAEGEAQPESEGIEAQEAEEEAQPELEGVEAPE 2184
Query: 1473 -EDEMSSASE--ESVLSVPELQETMEKLTWLASERRMSQEGESEEENSQEENSEPEEEEE 1529
E E SE E+ + E Q +E + +E E E E E ++PE E E
Sbjct: 2185 AEGEAQPESEGIEAPEAEGEAQPELEGVEAPEAEEEAQPEPEGVETPEAEGEAQPESEGE 2244
Query: 1530 EEAE--GMESLQKEDEMTDEAVGDSAEKPPTFASPETAPEVETSRTPPG 1576
+ E G + D ++EA S+ P +P +P +T PG
Sbjct: 2245 TQGEKKGSPQVSLGDGQSEEASESSSPVPEDRPTPPPSPGGDTPHQRPG 2293
Score = 50.8 bits (120), Expect = 1e-05
Identities = 51/225 (22%), Positives = 93/225 (41%), Gaps = 18/225 (8%)
Query: 1369 GEVTKQTVLQKEEERSQPTKTPSSSQ----EPPDEGTSGTDVNKGSSKNALSSMDPEVRL 1424
GE + Q+ E ++ ++T + S+ E EG S G ++ E
Sbjct: 1761 GEAEGDAMAQEREGKTHNSETSAGSELGEAEQEGEGISERGETGGQGSGHEDNLQGEAAA 1820
Query: 1425 SSP--PGKPEDSSSVDGQSVGTPVGPETGGEKNGPEEEEEEDFDDLTQDEEDEMSSASEE 1482
PG+ + + ++ PE+ G + E + ++ + Q E +++ + E
Sbjct: 1821 GGDQDPGQSDGAEGIEAPEAEGEAQPESEGVEAPEAEGDAQEAEGEAQPESEDVEAPEAE 1880
Query: 1483 SVLSVPELQ--ETMEKLTWLASERRMSQEGESEEENSQEENS----EPEEEEEEEAEGME 1536
+ PE + ET E + E ++ E+E+E E S E E E+E E+EG E
Sbjct: 1881 GE-AQPESEDVETPEAEWEVQPESEGAEAPEAEKEAQPETESVEALETEGEDEPESEGAE 1939
Query: 1537 SLQKEDEMTDEAVGDSAEKPPTFASPETAPEVETSRTPPGESIKA 1581
+ Q+ +E EA G + + S E E + P E ++A
Sbjct: 1940 A-QEAEEAAQEAEGQTQPESEVIESQEAEEEAQ----PESEDVEA 1979
Score = 45.8 bits (107), Expect = 5e-04
Identities = 56/237 (23%), Positives = 86/237 (36%), Gaps = 37/237 (15%)
Query: 1399 EGTSGTDVNKGSSKNALSSMDPEVRLSSPP---GKPEDSSSVDGQSVGTPVGPET----G 1451
E +G D + G S A PE + P G + D Q PE+
Sbjct: 1817 EAAAGGDQDPGQSDGAEGIEAPEAEGEAQPESEGVEAPEAEGDAQEAEGEAQPESEDVEA 1876
Query: 1452 GEKNGPEEEEEEDFDDLTQDEEDEMSSASEESVLSVPELQETMEKLTWLASERRMSQEGE 1511
E G + E ED + + E + S E+ + E Q E + L +E E E
Sbjct: 1877 PEAEGEAQPESEDVETPEAEWEVQPESEGAEAPEAEKEAQPETESVEALETEG----EDE 1932
Query: 1512 SEEENSQE---------------------ENSEPEEEEEEEAEGMESLQKEDEMTDEAVG 1550
E E ++ E+ E EEE + E+E +E+L+ E E T EA G
Sbjct: 1933 PESEGAEAQEAEEAAQEAEGQTQPESEVIESQEAEEEAQPESEDVEALEVEVE-TQEAEG 1991
Query: 1551 DSAEKPPTFASPET---APEVETSRTPPGESIKAAGKGRNNHRARNKRGSRARASKD 1604
++ + +PE E E P + ++A K A+ G + D
Sbjct: 1992 EAQPESEDVEAPEAEGEMQEAEEEAQPESDGVEAQPKS-EGEEAQEVEGETQKTEGD 2047
Score = 44.7 bits (104), Expect = 0.001
Identities = 73/352 (20%), Positives = 129/352 (36%), Gaps = 39/352 (11%)
Query: 1801 DGFEEVALPDVEEEEEPP----KIPTASKNKRKKEIGVQNHDKETEWPDGAKDCACSCHE 1856
DG E + P+ E E +P + P A + ++ E Q ++ E P+ E
Sbjct: 1830 DGAEGIEAPEAEGEAQPESEGVEAPEAEGDAQEAEGEAQPESEDVEAPEAEG-------E 1882
Query: 1857 GGPDSKLKKSKRRSCSHCSSKVCDSKSYKSKEPHELVGSSPHREASPMPGAKEA--GQGK 1914
P+S+ + +++ E +EA P + EA +G+
Sbjct: 1883 AQPESE------------DVETPEAEWEVQPESEGAEAPEAEKEAQPETESVEALETEGE 1930
Query: 1915 DMMEEEAPEERESTEATQSRTVRTTRKGEMPVSGLAVGSTLPSPREVTVTERLL----LD 1970
D E E E +E+ EA Q +T + E+ S A P +V E + +
Sbjct: 1931 DEPESEGAEAQEAEEAAQEAEGQTQPESEVIESQEAEEEAQPESEDVEALEVEVETQEAE 1990
Query: 1971 GPPPHSPETPQFPPTTGAVLYTVKRNQVGPE-VRSCPKASPRLQKEREGQK------AVS 2023
G E + P G + + Q + V + PK+ +E EG+ A
Sbjct: 1991 GEAQPESEDVEAPEAEGEMQEAEEEAQPESDGVEAQPKSEGEEAQEVEGETQKTEGDAQP 2050
Query: 2024 ESEALMLVWDASETEKLPGTVEPPASFLSPVSSKTRDAGRRHVSGKPDTQERWLPSSRAR 2083
ES+ + E ++ G V+ P S DA +P+++ P +
Sbjct: 2051 ESDGVEAPEAEEEAQEAEGEVQEAEGEAHPESEDV-DAQEAEGEAQPESEGVEAPEAEGE 2109
Query: 2084 V-KTRDRTCPVHESPSGIDTSET-SPKAPRGGLAKDSGTQAKGPEGEQQPKA 2133
K P E + ++ +P+A + G +A+ EGE QP++
Sbjct: 2110 AQKAEGIEAPETEGEAQPESEGIEAPEAEGEAQPESEGVEAQDAEGEAQPES 2161
Score = 38.9 bits (89), Expect = 0.057
Identities = 26/97 (26%), Positives = 45/97 (46%), Gaps = 1/97 (1%)
Query: 1460 EEEEDFDDLTQDEEDEMSSASEESVLSVPELQETMEKLTWLASERRMSQEGESE-EENSQ 1518
E+E + D Q + +E +V +L+ET E + Q E++ EE Q
Sbjct: 1273 EDEAERDSEEQRASSNLEQLAENTVQEEVQLEETKEGTEGEGLQEEAVQLEETKTEEGLQ 1332
Query: 1519 EENSEPEEEEEEEAEGMESLQKEDEMTDEAVGDSAEK 1555
EE + EE +E E EG + + + E +E G+ ++
Sbjct: 1333 EEGVQLEETKETEGEGQQEEEAQLEEIEETGGEGLQE 1369
Score = 35.0 bits (79), Expect = 0.83
Identities = 59/273 (21%), Positives = 90/273 (32%), Gaps = 25/273 (9%)
Query: 1883 SYKSKEPHELVGSSPHREASPMPGAKEAGQGKDMMEEEAPEERESTEATQSRTVRTTRKG 1942
S+ K+ H + SS ++ P + A Q + P S+ +T+++ R
Sbjct: 668 SHYRKDTHSPLDSSVTKQVPRPPERRRACQ-----DGSVPRYSGSSSSTRTQASGNLRP- 721
Query: 1943 EMPVSGLAVGSTLPSPREVTVTERLLLD---GPPPHSPETPQFPPTTGAVLYTVKRNQVG 1999
P SG L TVT + D G PH+ + + G+ T +
Sbjct: 722 --PSSGSLPSQDLLGTSSATVTPAVHSDFVSGVSPHNAPSAGWAGDAGS--RTCSPAPIP 777
Query: 2000 PEVRSCPKASPRLQKEREGQKAVSESEALMLVWDASETEKLPGTVEPPASFL--SPVSSK 2057
P S E + S L+L E G V P S P +
Sbjct: 778 PHTSDSCSKSGAASLGEEARDTPQPSSPLVLQVGRPEQ----GAVGPHRSHCCSQPGTQP 833
Query: 2058 TRDAGRRHVSGKPDTQERWLPSSRARVKTRDRTCPVHESPSGIDTSETSPKAPRG-GLAK 2116
++A R P + WL R R CP S S T + RG G +
Sbjct: 834 AQEAQRG-----PSPEASWLCGRYCPTPPRGRPCPQRRSSSCGSTGSSHQSTARGPGGSP 888
Query: 2117 DSGTQAKGPEGEQQPKAAEATVCANNSKVSSTG 2149
GT+ GP P + + + + S G
Sbjct: 889 QEGTRQPGPTPSPGPNSGASRRSSASQGAGSRG 921
Score = 34.7 bits (78), Expect = 1.1
Identities = 42/166 (25%), Positives = 70/166 (42%), Gaps = 14/166 (8%)
Query: 1273 LADAECQEGLSENSACRWTVVKTE-EGRQALEPLPQGIQESLNNPTPGDLEEIVKMEPEE 1331
L + + +EGL E +TE EG+Q E + I+E+ G EE V++E E
Sbjct: 1322 LEETKTEEGLQEEGVQLEETKETEGEGQQEEEAQLEEIEETGGE---GLQEEGVQLE--E 1376
Query: 1332 AREEISGSPERDICDDIKVEHAVELDTGAPSEELSSA----GEVTKQTVLQKEEERSQPT 1387
+E G + + ++ E + + +ELS A G+ +++ +EEE + +
Sbjct: 1377 VKEGPEGGLQGEALEEGLKEEGLPEEGSVHGQELSEASSPDGKGSQEDDPVQEEEAGRAS 1436
Query: 1388 KT----PSSSQEPPDEGTSGTDVNKGSSKNALSSMDPEVRLSSPPG 1429
+ P+ E P E S S+ S E L PPG
Sbjct: 1437 ASAEPCPAEGTEEPTEPPSHLSETDPSASERQSGSQLEPGLEKPPG 1482
Score = 33.5 bits (75), Expect = 2.4
Identities = 53/276 (19%), Positives = 110/276 (39%), Gaps = 13/276 (4%)
Query: 161 SEEVKEEGGKPQMNSEGEIPSLPSGSQSAKPVSQPRKSTQPDVCASPQEKPLRTLFHQPE 220
SE+V+ + + E E P +P S+ ++ + + A P+ + + L + E
Sbjct: 1871 SEDVEAPEAEGEAQPESEDVETPEAEWEVQPESEGAEAPEAEKEAQPETESVEALETEGE 1930
Query: 221 EEIEDGGLFIPMEEQDNEESEKRRKKKKGTKRKRDGRGQEGTLAYDLKLDDMLDRTLE-D 279
+E E G E+ +E+E + + + ++ + + D++ ++ T E +
Sbjct: 1931 DEPESEGAEAQEAEEAAQEAEGQTQPESEVIESQEAEEEAQPESEDVEALEVEVETQEAE 1990
Query: 280 GAKQHNLTAVNVRNILHEVITNEHVVAMMKAAISETEDMPMFEPKMTRSKLKEVVEKGVV 339
G Q V E+ E + A E++ + +PK + +EV +G
Sbjct: 1991 GEAQPESEDVEAPEAEGEMQEAE------EEAQPESDGVEA-QPKSEGEEAQEV--EGET 2041
Query: 340 IPTWNISPIKKANEIKPPQFVDIHLEEDDSSDEEYQPDDEEEDETAEESLLESDVEST-A 398
T + + P + E + + E + E ED A+E+ E+ ES
Sbjct: 2042 QKTEGDAQPESDGVEAPEAEEEAQEAEGEVQEAEGEAHPESEDVDAQEAEGEAQPESEGV 2101
Query: 399 SSPRGAKKSRLRQSSEMTETDEESGILSEAEKVTTP 434
+P +++ + E ET+ E+ E+E + P
Sbjct: 2102 EAPEAEGEAQKAEGIEAPETEGEA--QPESEGIEAP 2135
>gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Homo
sapiens]
Length = 1152
Score = 70.9 bits (172), Expect = 1e-11
Identities = 81/315 (25%), Positives = 117/315 (37%), Gaps = 25/315 (7%)
Query: 1307 QGIQESLNNPTPGDLEEIVKMEPEEAREEISGSPERDICDDIKVEHAVELDTGAPSEELS 1366
+G +E G+ E K E E +EE +G E+ + + E E +T EE
Sbjct: 754 EGKEEGEGEEVEGERE---KEEGERKKEERAGKEEKGEEEGDQGEGEEE-ETEGRGEEKE 809
Query: 1367 SAGEVTKQTV------LQKEEERSQPTKTPSSSQEPPDEGTSGTDVNKGSSKNALSSMDP 1420
GEV V ++EEE + + +E EG KG + +
Sbjct: 810 EGGEVEGGEVEEGKGEREEEEEEGEGEEEEGEGEEEEGEGEEEEGEGKGEEEGEEGEGEE 869
Query: 1421 EVRLSSPPGKPEDSSSVDGQSVGTPVGPETGGEKNGPEEEE----EEDFDDLTQDEEDEM 1476
E G+ E+ +G+ G G E GE G EE E EE+ + ++E +E
Sbjct: 870 EGEEGEGEGEEEEGEG-EGEEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGKGEEEGEEG 928
Query: 1477 SSASEESVLSVP----ELQETMEKLTWLASERRMSQEGESEEENSQEENSEPEEEEEEEA 1532
EE E + E+ W E EGE E E EE EEEE E
Sbjct: 929 EGEGEEEEGEGEGEDGEGEGEEEEGEWEGEEEEGEGEGEEEGEGEGEEGEGEGEEEEGEG 988
Query: 1533 EGMESLQKEDEMTDEAVGDSAEKPPTFASPETAPEVE---TSRTPPGESIKAAGKGRNNH 1589
EG E +E E E G+ E+ E EVE GE + G+
Sbjct: 989 EGEE---EEGEEEGEEEGEGEEEGEGEGEEEEEGEVEGEVEGEEGEGEGEEEEGEEEGEE 1045
Query: 1590 RARNKRGSRARASKD 1604
R + G R +++
Sbjct: 1046 REKEGEGEENRRNRE 1060
Score = 58.2 bits (139), Expect = 9e-08
Identities = 76/294 (25%), Positives = 111/294 (37%), Gaps = 32/294 (10%)
Query: 1266 EHSPGPPLADAECQEGLSENSACRWTVVKTEEGRQALEPLPQGIQESLNNPTPGDLEEIV 1325
E G + E +EG E EE + E +G +E + EE
Sbjct: 807 EKEEGGEVEGGEVEEGKGEREEEEEEGEGEEEEGEGEEEEGEGEEEEGEGKGEEEGEE-- 864
Query: 1326 KMEPEEAREEISGSPERDICDDIKVEHAVELDTGAPSEELSSAGEVTKQTVLQKEEERSQ 1385
E EE EE G E + + E E + EE GE ++ + EEE +
Sbjct: 865 -GEGEEEGEEGEGEGEEE-----EGEGEGEEEGEGEGEEEEGEGEGEEEGEGEGEEEEGE 918
Query: 1386 PTKTPSSSQEPPDEGTSGTDVNKGSSKNALSSMDPEVRLSSPPGKPEDSSSVDGQSVGTP 1445
+E +EG + +G + + E G+ E+ +G+ G
Sbjct: 919 -----GKGEEEGEEGEGEGEEEEGEGEGEDGEGEGEEEEGEWEGEEEEGEG-EGEEEGEG 972
Query: 1446 VGPETGGEKNGPEEEEEEDFDDLTQDEEDEMSSASEESVLSVPELQETMEKLTWLASERR 1505
G E GE G EEE E + ++ +EE E EE E +E E + E
Sbjct: 973 EGEE--GEGEGEEEEGEGEGEEEEGEEEGEEEGEGEEEGEGEGEEEEEGEVEGEVEGE-- 1028
Query: 1506 MSQEGESEEENSQEENSE-------------PEEEEEEEAEGMESLQKEDEMTD 1546
EGE EEE +EE E EEEEEEE + E+ ++E+E D
Sbjct: 1029 -EGEGEGEEEEGEEEGEEREKEGEGEENRRNREEEEEEEGKYQETGEEENERQD 1081
Score = 50.1 bits (118), Expect = 2e-05
Identities = 72/287 (25%), Positives = 101/287 (35%), Gaps = 17/287 (5%)
Query: 1319 GDLEEIVKMEPEEAREEISGSPERDICDDIKVEHAVELDTGAPSEELSSA-----GEVTK 1373
G++EE K E EE EE G E ++ + E E G EE GE +
Sbjct: 817 GEVEE-GKGEREEEEEEGEGEEEEGEGEEEEGEGEEEEGEGKGEEEGEEGEGEEEGEEGE 875
Query: 1374 QTVLQKEEERSQPTKTPSSSQEPPDEGTSGTDVNKGSSKNALSSMDPEVRLSSPPGKPED 1433
++E E + +E EG G + +G + E G+ E+
Sbjct: 876 GEGEEEEGEGEGEEEGEGEGEEEEGEG-EGEEEGEGEGEEEEGEGKGEEEGEEGEGEGEE 934
Query: 1434 SSSVDGQSVGTPVGPETGGEKNGPEEEEEEDFDDLTQDEEDEMSSASEESVLSVPELQET 1493
G G E GE G EEE E + ++ + E +E EE +E
Sbjct: 935 EEGEGEGEDGEGEGEEEEGEWEGEEEEGEGEGEEEGEGEGEEGEGEGEEEEGEGEGEEEE 994
Query: 1494 MEKLTWLASERRMSQEGESEEENSQEENSEPE---EEEEEEAEGMESLQKEDEMTDEAVG 1550
E+ E E E E E +EE E E E EE E EG E +E+ E G
Sbjct: 995 GEE----EGEEEGEGEEEGEGEGEEEEEGEVEGEVEGEEGEGEGEEEEGEEEGEEREKEG 1050
Query: 1551 DSAEKPPTFASPETAPEVETSRTPPGESIKAAGKGRNNHRARNKRGS 1597
+ E + E E E GE G + +GS
Sbjct: 1051 EGEENR---RNREEEEEEEGKYQETGEEENERQDGEEYKKVSKIKGS 1094
Score = 48.9 bits (115), Expect = 6e-05
Identities = 78/329 (23%), Positives = 121/329 (36%), Gaps = 43/329 (13%)
Query: 1296 EEGRQALEPLPQGI---QESLNNPTPGDLEEIVKMEPEEAREEISGS--PERDIC---DD 1347
+EG+ + + QGI Q + D EE+ E +E E+ G+ E+++ ++
Sbjct: 554 KEGKACKQHVSQGIFMTQPATTIEAFSD-EEVEIPEEKEGAEDSKGNGIEEQEVEANEEN 612
Query: 1348 IKVEHAVELDTGAPSEELSSAGEVTKQTVLQKEEERSQPTKTPSSSQEPPDEGTSGTDV- 1406
+KV + T S++L+ EV++ E P + E EG+SG +
Sbjct: 613 VKVHGGRKEKTEILSDDLTDKAEVSEGKAKSVGEAEDGPEGRGDGTCE---EGSSGAEHW 669
Query: 1407 -----NKGSSKNALSSMDPEVRLSSPPGKPEDSSSVDG------------QSVGTPVGPE 1449
KG M+ + E+ DG Q E
Sbjct: 670 QDEEREKGEKDKGRGEMERPGEGEKELAEKEEWKKRDGEEQEQKEREQGHQKERNQEMEE 729
Query: 1450 TGGEKNGPEEEEEEDFDDLTQDEEDEMSSASEESVLSVPELQETMEKLTWLASERRMSQE 1509
G E++G EEEE D ++ + E + E V E +E K E R +E
Sbjct: 730 GGEEEHGEGEEEEGDREEEEEKEGEGKEEGEGEEVEGEREKEEGERK-----KEERAGKE 784
Query: 1510 GESEEENSQEENSEPEEE--EEEEAEGMESLQKEDEMTDEAVGDSAEKPPTFASPETAPE 1567
+ EEE Q E E E E EE+ EG E E +E G+ E+ E E
Sbjct: 785 EKGEEEGDQGEGEEEETEGRGEEKEEGGE---VEGGEVEEGKGEREEEEEEGEGEEEEGE 841
Query: 1568 VETSRTPPGESIKAAGKGRNNHRARNKRG 1596
E GE + G+G+ G
Sbjct: 842 GEEEE---GEGEEEEGEGKGEEEGEEGEG 867
Score = 39.3 bits (90), Expect = 0.044
Identities = 63/277 (22%), Positives = 95/277 (34%), Gaps = 38/277 (13%)
Query: 1275 DAECQEGLSENSACRWTVVKTEEGRQALEPLPQGIQESLNNPTPGDLEEIVKMEPEE--- 1331
+ E +EG E + E + E +G E G+ EE + E EE
Sbjct: 841 EGEEEEGEGEEEEGEGKGEEEGEEGEGEEEGEEGEGEGEEEEGEGEGEEEGEGEGEEEEG 900
Query: 1332 ---AREEISGSPERDICDDIKVEHAVELDTGAPSEELSSAGEVTKQTVLQKEEERSQPTK 1388
EE G E + + E E + EE GE + +EEE +
Sbjct: 901 EGEGEEEGEGEGEEEEGEGKGEEEGEEGEGEGEEEEGEGEGEDGEGE--GEEEEGEWEGE 958
Query: 1389 TPSSSQEPPDEGTSGTDVNKGSSKNALSSMDPEVRLSSPPGKPEDSSSVDGQSVGTP--- 1445
E +EG + +G + + E G+ E +G+ G
Sbjct: 959 EEEGEGEGEEEGEGEGEEGEGEGEEEEGEGEGEEEEGEEEGEEEGEGEEEGEGEGEEEEE 1018
Query: 1446 --VGPETGGEKNGPEEEEEEDFDDLTQDEEDEMSSASEESVLSVPELQETMEKLTWLASE 1503
V E GE+ E EEEE ++ EE E EE+
Sbjct: 1019 GEVEGEVEGEEGEGEGEEEEGEEE---GEEREKEGEGEEN-------------------- 1055
Query: 1504 RRMSQEGESEEENSQEENSEPEEEEEEEAEGMESLQK 1540
R ++E E EEE +E E EE E ++ E + + K
Sbjct: 1056 -RRNREEEEEEEGKYQETGE-EENERQDGEEYKKVSK 1090
Score = 36.2 bits (82), Expect = 0.37
Identities = 69/329 (20%), Positives = 118/329 (35%), Gaps = 44/329 (13%)
Query: 1310 QESLNNPTPGD--LEEIVKMEPEEAREEISGSPER--DICDDIKVEHAVELDTGAPSEEL 1365
++ L P D L+E+ K EA + S + E + D + + H + L++ S +L
Sbjct: 462 EQDLMQPEEPDYLLDEMTK----EAEIDNSSTVESLGETTDILNMTHIMSLNSNEKSLKL 517
Query: 1366 S---------SAGEVTKQTVLQK-----EEERSQPTKTPSSSQEPPDEGTSGTDVNKGSS 1411
S + GE+T+ T L + E E K + ++ +G T ++
Sbjct: 518 SPVQKQKKQQTIGELTQDTALTENDDSDEYEEMSEMKEGKACKQHVSQGIFMTQ--PATT 575
Query: 1412 KNALSSMDPEVRLSSPPGKPEDSSSVDGQSVGTPVGPETGGEKNGPEEEEEEDFDDLTQD 1471
A S D EV + EDS + E G +E+ E DDLT
Sbjct: 576 IEAFS--DEEVEIPEEKEGAEDSKGNGIEEQEVEANEENVKVHGGRKEKTEILSDDLTDK 633
Query: 1472 EEDEMSSASEESVLSVPELQE--------TMEKLT-----WLASERRMSQEGESEEENSQ 1518
E SE SV E ++ T E+ + W ER ++ + E +
Sbjct: 634 AE-----VSEGKAKSVGEAEDGPEGRGDGTCEEGSSGAEHWQDEEREKGEKDKGRGEMER 688
Query: 1519 EENSEPEEEEEEEAEGMESLQKEDEMTDEAVGDSAEKPPTFASPETAPEVETSRTPPGES 1578
E E E+EE + + ++E + ++ + E E E E
Sbjct: 689 PGEGEKELAEKEEWKKRDGEEQEQKEREQGHQKERNQEMEEGGEEEHGEGEEEEGDREEE 748
Query: 1579 IKAAGKGRNNHRARNKRGSRARASKDTSK 1607
+ G+G+ G R + + K
Sbjct: 749 EEKEGEGKEEGEGEEVEGEREKEEGERKK 777
Score = 36.2 bits (82), Expect = 0.37
Identities = 42/164 (25%), Positives = 61/164 (37%), Gaps = 22/164 (13%)
Query: 1785 GDFEEINWTEEKEYEFDGFEEVALPDVE-----EEEEPPKIPTASKNKRKKEIGVQNHDK 1839
G+ EE + EE+E E +G EE +VE EE E K A K ++ +E G Q +
Sbjct: 738 GEEEEGDREEEEEKEGEGKEEGEGEEVEGEREKEEGERKKEERAGKEEKGEEEGDQGEGE 797
Query: 1840 ETEWPDGAKDCACSCHEGGPDSKLKKSKRRSCSHCSSKVCDSKSYKSKEPHELVGSSPHR 1899
E E ++ EGG +V + K + +E E G
Sbjct: 798 EEETEGRGEE----KEEGGEVE-------------GGEVEEGKGEREEEEEEGEGEEEEG 840
Query: 1900 EASPMPGAKEAGQGKDMMEEEAPEERESTEATQSRTVRTTRKGE 1943
E G E +G+ EEE E E + +GE
Sbjct: 841 EGEEEEGEGEEEEGEGKGEEEGEEGEGEEEGEEGEGEGEEEEGE 884
Score = 32.0 bits (71), Expect = 7.0
Identities = 24/72 (33%), Positives = 30/72 (41%), Gaps = 5/72 (6%)
Query: 365 EEDDSSDEEYQPDDEEEDETAEESLLE---SDVESTASSPRGAKKSRLRQSSEMTETDEE 421
EE+ EE + D EEE+E E E +VE G +K R E E EE
Sbjct: 732 EEEHGEGEEEEGDREEEEEKEGEGKEEGEGEEVEGEREKEEGERKKEERAGKE--EKGEE 789
Query: 422 SGILSEAEKVTT 433
G E E+ T
Sbjct: 790 EGDQGEGEEEET 801
>gi|146219843 Snf2-related CBP activator protein [Homo sapiens]
Length = 3230
Score = 70.9 bits (172), Expect = 1e-11
Identities = 94/352 (26%), Positives = 140/352 (39%), Gaps = 85/352 (24%)
Query: 1237 DGENAFQGLEPKLEPQELSPLSATVFPKVEHSPGPPLADAECQEGLSENSACRWTVVKTE 1296
+GE + L L PQ L S+ S P D++ ++G E + E
Sbjct: 327 EGELPLEELLRSLPPQLLEGPSSP-------SQTPSSHDSDTRDGPEEGAE--------E 371
Query: 1297 EGRQALE--PLPQGIQESLNNP--TPGDLEEIVKMEPEEAREEISGSPERDICDDIKVEH 1352
E Q LE P P + + P D EE E E EE + + E + + +V+H
Sbjct: 372 EPPQVLEIKPPPSAVTQRNKQPWHPDEDDEEFTANEEEAEDEEDTIAAEEQL--EGEVDH 429
Query: 1353 AVELDTGAPSEELSSAGEVTKQTVLQKEEERSQPTKTPSSSQEPPDEGTSGTDVNKGSSK 1412
A+EL EL+ GE++ + +LQ+ P + SS E DE D N
Sbjct: 430 AMELS------ELAREGELSMEELLQQYAGAYAPG-SGSSEDEDEDE----VDANS---- 474
Query: 1413 NALSSMDPEVRLSSPPGKPEDSSSVDGQSVGTPVGPETGGEKNGPEEEEEEDFDDLTQDE 1472
S +PE + + EDSSS + + E+ E++ D+ +++E
Sbjct: 475 ---SDCEPEGPVEAEEPPQEDSSS----------------QSDSVEDRSEDEEDEHSEEE 515
Query: 1473 EDEMSSASEESVLSVPELQETMEKLTWLASERRMSQEGESEEENSQEENSEPEEEEEEEA 1532
E SSASEES ESEE + S+ +EEEE++
Sbjct: 516 ETSGSSASEES---------------------------ESEESEDAQSQSQADEEEEDDD 548
Query: 1533 EGMESLQKEDEMTDEAVGDSAEKPPTFASPETAPEVE-TSRTPPGESIKAAG 1583
G+E L DE EA D+ PPT P+ E T ES++ G
Sbjct: 549 FGVEYLLARDEEQSEA--DAGSGPPTPGPTTLGPKKEITDIAAAAESLQPKG 598
Score = 63.9 bits (154), Expect = 2e-09
Identities = 74/294 (25%), Positives = 120/294 (40%), Gaps = 47/294 (15%)
Query: 1003 PLLIQPSPSLQPSFNPGKTPARSTHSEAPPS----KMVLRIPHPIQPATVLQTVPGVPPL 1058
P ++ P P+L P P TP T P+ + +L++ H P V + PG PL
Sbjct: 1339 PAVLNPRPTLTPGRLP--TPTLGTARAPMPTPTLVRPLLKLVHSPSPE-VSASAPGAAPL 1395
Query: 1059 GVSGG----ESFESPAALPA-VPPEARTSFPLSESQTLLSSAPVPKVMLPSLAPSKFRKP 1113
+S S PA+ P +P + + P+S + ++ S+ +P + +P+ P+ P
Sbjct: 1396 TISSPLHVPSSLPGPASSPMPIPNSSPLASPVSSTVSVPLSSSLP-ISVPTTLPAPASAP 1454
Query: 1114 YVRRRPSKRRGVKASPCMKPAPVIHHPASVIFTVPATTVKIVSLGGGCNMIQPVNAAVAQ 1173
P P V +++ +V +V G + P A+ +
Sbjct: 1455 LT------------IPISAPLTVSASGPALLTSVTPPLAPVVPAAPGPPSLAPSGASPSA 1502
Query: 1174 SPQTIPITT-------------LLVNPTSFPCPLNQSLVASSVSPLIVSGNSVNLPIPST 1220
S T+ + T LL+ PTS P S VA + SP++V +++ P PS
Sbjct: 1503 SALTLGLATAPSLSSSQTPGHPLLLAPTSSHVPGLNSTVAPACSPVLVPASALASPFPSA 1562
Query: 1221 PEDKAHVNVDIACAVADGENAFQGLEPKLEPQELSPLSATVFPKVEHSPGPPLA 1274
P A +A +A Q L L P +P +A + P SP PPLA
Sbjct: 1563 PNPAPAQ----ASLLAPASSASQALATPLAPM-AAPQTAILAP----SPAPPLA 1607
Score = 52.4 bits (124), Expect = 5e-06
Identities = 97/392 (24%), Positives = 146/392 (37%), Gaps = 93/392 (23%)
Query: 1085 LSESQTLLSSAPVPKVMLPSLAPSKFR--KPYVRRRPSKRRGVKASPCMKPAPVIHHPAS 1142
+S QT ++ P P +P++ R +P R RP+ A P + P PV P
Sbjct: 2415 ISAHQTRSTTTP------PRCSPARERVPRPAPRPRPTPASAPAAIPALVPVPV-SAPVP 2467
Query: 1143 VIFTVPATTVKIVSLGGGCNMIQPVNAAVAQSPQTIPITTLLVNPTSFPCPLNQSLVASS 1202
+ P T + + L + P SP P P P P LV S
Sbjct: 2468 ISAPNPITILPVHILP---SPPPPSQIPPCSSPACTPPPACTPPPAHTPPPAQTCLVTPS 2524
Query: 1203 VSPLI-------VSGNSVNLPIPSTPEDK-------AHVNVDIACAVADGENAFQGLEPK 1248
SPL+ +S + NLP+ PE + + ++++A +VA E + L P
Sbjct: 2525 -SPLLLGPPSVPISASVTNLPLGLRPEAELCAQALASPESLELA-SVASSETSSLSLVP- 2581
Query: 1249 LEPQELSPLSATVFPKVEHS----PGPPLADAEC------QEGLSENSACRWTVVKTEEG 1298
P++L P++ + P E + P P E QE + +SA T+ EG
Sbjct: 2582 --PKDLLPVAVEILPVSEKNLSLTPSAPSLTLEAGSIPNGQEQEAPDSAEGTTLTVLPEG 2639
Query: 1299 RQALEPLPQGIQESLNNPTPGDLEEIVKMEPEEAREEISGSPERDICDDIKVEHAVELDT 1358
E LP + ES +++ P A +E P L+
Sbjct: 2640 ----EELPLCVSESNG----------LELPPSAASDEPLQEP---------------LEA 2670
Query: 1359 GAPSEELSSAGEVTKQTVLQKEEERSQPTKTPSSSQEPPDEGTSGTDVNKGSSKNALSSM 1418
SEEL+ A KTP+SS E P E + +S +A SS
Sbjct: 2671 DRTSEELTEA-------------------KTPTSSPEKPQELVTAEVAAPSTSSSATSS- 2710
Query: 1419 DPEVRLSSPPGKPEDSSSVD--GQSVGTPVGP 1448
PE + P + S+ V+ GQ G P P
Sbjct: 2711 -PEGPSPARPPRRRTSADVEIRGQGTGRPGQP 2741
Score = 50.8 bits (120), Expect = 1e-05
Identities = 58/232 (25%), Positives = 90/232 (38%), Gaps = 22/232 (9%)
Query: 1008 PSPSLQPSFNPGKTPARSTHSEAPPSKMVLRIPHPIQPATVLQTVPGVPPLGVSGGESFE 1067
P P + PS PG + A ++ AP + P++ +P P + S +
Sbjct: 1628 PVPVMAPSSTPGTSLASASPVPAPTPVLA--------PSSTQTMLPAPVPSPLPSPASTQ 1679
Query: 1068 SPAALPAVPPEARTSFPLSESQTLLSSAPVPKVMLP----SLAPSKFRKPYVRRRPSKRR 1123
+ A PA+ P S P SQTL P+ P SL P+ P + S
Sbjct: 1680 TLALAPALAPTLGGSSP---SQTLSLGTGNPQGPFPTQTLSLTPASSLVPTPAQTLSLAP 1736
Query: 1124 GVKASP----CMKPAPVIHHPASVIFTVPATTVKIVSLGGGCNMIQPVNA-AVAQSPQTI 1178
G P + PAP + PAS + PA T+ + +++ P + + SP +
Sbjct: 1737 GPPLGPTQTLSLAPAPPL-APASPVGPAPAHTLTLAPASSSASLLAPASVQTLTLSPAPV 1795
Query: 1179 PITTLLVNPTSFPCPLNQSLVASSVSPLIVSGNSVNLPIPSTPEDKAHVNVD 1230
P T P + AS S L+VS + P+P T + V+ D
Sbjct: 1796 PTLGPAAAQTLALAPASTQSPASQASSLVVSASGA-APLPVTMVSRLPVSKD 1846
Score = 37.4 bits (85), Expect = 0.17
Identities = 92/430 (21%), Positives = 161/430 (37%), Gaps = 57/430 (13%)
Query: 1804 EEVALPDVEEEEEPPKIPTASKNKRKKEIGVQNHDKETEWPDGAKDCACSCHEGGPDSKL 1863
EEV+ ++++ EE + ++ K+E+ + +E E P + +C GG +
Sbjct: 2325 EEVSREELKQAEEQVEAARKDLDQAKEEV-FRLPQEEEEGPGAGDESSCGTG-GGTHRRS 2382
Query: 1864 KKSK--RRSCSHCSSKVCDSKSYKSKEPHELVGSSPHREASPMPGAKEAGQGKDMMEEEA 1921
KK+K R + S ++ +++ H V S+ ++ P ++ + A
Sbjct: 2383 KKAKAPERPGTRVSERLRGARAETQGANHTPVISAHQTRSTTTP--PRCSPARERVPRPA 2440
Query: 1922 PEERE---STEATQSRTVRTTRKGEMPVSGLAVGSTLPSPREVTVTERLLLDGPPPHSPE 1978
P R S A V +P+S +P +T+ +L PPP S
Sbjct: 2441 PRPRPTPASAPAAIPALVPVPVSAPVPIS---------APNPITILPVHILPSPPPPS-- 2489
Query: 1979 TPQFPPTTGAVLYTVKRNQVGPEVRSCPKASPRLQKEREGQKAVSESEALML----VWDA 2034
Q PP + T P + P A L V+ S L+L V +
Sbjct: 2490 --QIPPCSSPAC-TPPPACTPPPAHTPPPAQTCL---------VTPSSPLLLGPPSVPIS 2537
Query: 2035 SETEKLPGTVEPPASFLSPVSSKTRDAGRRHVSGKPDTQERWLPSSRARVKTRDRTCPVH 2094
+ LP + P A + + V+ +T L + + PV
Sbjct: 2538 ASVTNLPLGLRPEAELCAQALASPESLELASVASS-ETSSLSLVPPKDLLPVAVEILPVS 2596
Query: 2095 ESPSGIDTSETSPKAPRGGLAKDSGTQAKGPEGEQQPKAAEATVCANNSKVSSTGEKVVL 2154
E + +P AP L ++G+ G E ++ P +AE T V GE++ L
Sbjct: 2597 EKNLSL-----TPSAP--SLTLEAGSIPNGQE-QEAPDSAEGTTLT----VLPEGEELPL 2644
Query: 2155 WTREADRVIL---TMCQEQGAQPQTFNIISQQLGN-KTPAEVSHRFRELMQLFHTACEAS 2210
E++ + L E +P + S++L KTP + +EL+ TA A+
Sbjct: 2645 CVSESNGLELPPSAASDEPLQEPLEADRTSEELTEAKTPTSSPEKPQELV----TAEVAA 2700
Query: 2211 SEDEDDATST 2220
ATS+
Sbjct: 2701 PSTSSSATSS 2710
Score = 35.4 bits (80), Expect = 0.63
Identities = 31/106 (29%), Positives = 44/106 (41%), Gaps = 6/106 (5%)
Query: 1004 LLIQPSPSLQPSFNPGKTPARSTHSEAPPSKMVLRIPHPIQPATVLQTVPGVPPLGVSGG 1063
L + P+P L P+ G PA + S L P +Q T L P VP LG +
Sbjct: 1746 LSLAPAPPLAPASPVGPAPAHTLTLAPASSSASLLAPASVQTLT-LSPAP-VPTLGPAAA 1803
Query: 1064 ESFESPAALPAVPPEARTSFPLSESQTLLSSAPVPKVMLPSLAPSK 1109
++ A P +S +S S +AP+P M+ L SK
Sbjct: 1804 QTLALAPASTQSPASQASSLVVSAS----GAAPLPVTMVSRLPVSK 1845
Score = 35.0 bits (79), Expect = 0.83
Identities = 76/380 (20%), Positives = 140/380 (36%), Gaps = 72/380 (18%)
Query: 137 RPGPVTQEDRCDHLTLKEPFSGEPSEEVKEEGGKPQMNSEGEIP------SLPSGS-QSA 189
+P +ED + + ++E G +E + E + EGE+P SLP +
Sbjct: 290 QPQEDEEEDDEETIEVEEQQEGNDAEAQRRE--IELLRREGELPLEELLRSLPPQLLEGP 347
Query: 190 KPVSQPRKSTQPDVCASPQEKPLRTLFHQPEEEIEDGGLFIPMEEQDNEESEKRRKKKKG 249
SQ S D P+E +P + +E + +++ + ++
Sbjct: 348 SSPSQTPSSHDSDTRDGPEEGAEE----EPPQVLEIKPPPSAVTQRNKQPWHPDEDDEEF 403
Query: 250 TKRKRDGRGQEGTLAYDLKLDDMLDRTLE--DGAKQHNLTAVNVRNILHEVITNEHVVAM 307
T + + +E T+A + +L+ +D +E + A++ L+ + E++
Sbjct: 404 TANEEEAEDEEDTIAAEEQLEGEVDHAMELSELAREGELS-------MEELLQQYAGAYA 456
Query: 308 MKAAISETEDMPMFEPKMTRSKLKEVVEKGVVIPTWNISPIKKANEIKPPQFVDIHLEED 367
+ SE ED E V + + P +PPQ +
Sbjct: 457 PGSGSSEDED-----------------EDEVDANSSDCEPEGPVEAEEPPQ--------E 491
Query: 368 DSSDEEYQPDDEEEDETAEESLLESDVESTASSPRGAKKSRLRQSSEMTETDEESG---- 423
DSS + +D EDE E S E S+AS +++S QS + +EE
Sbjct: 492 DSSSQSDSVEDRSEDEEDEHSEEEETSGSSASEESESEESEDAQSQSQADEEEEDDDFGV 551
Query: 424 --ILSEAEKVTTPAIRHISAEVVPMGPPPPPKPKQTRDSTFMEKLHAVDEELASSPVCMD 481
+L+ E+ +E PP P P +T K +E+ +
Sbjct: 552 EYLLARDEE---------QSEADAGSGPPTPGP-----TTLGPK-----KEITDIAAAAE 592
Query: 482 SFQPMDDSLIAFRTRSKMPL 501
S QP +L + ++ +PL
Sbjct: 593 SLQPKGYTLATTQVKTPIPL 612
Score = 32.3 bits (72), Expect = 5.4
Identities = 44/188 (23%), Positives = 66/188 (35%), Gaps = 31/188 (16%)
Query: 1448 PETGGEKNGPEEEEEEDFDDLTQ---------DEEDEMSSASEESVLSVPELQETMEKLT 1498
P + + PEEEEE T ++E+++ +A++ V EL E E
Sbjct: 2217 PSSSSVPSAPEEEEETVASKQTHILEQALCRAEDEEDIRAATQAKAEQVAELAEFNENDG 2276
Query: 1499 WLASE-RRMSQEGESEEENSQEENS--------EPEE-------EEEEEAEGMESLQKED 1542
+ A E + G +EE S+ E P E E E E L++ +
Sbjct: 2277 FPAGEGEEAGRPGAEDEEMSRAEQEIAALVEQLTPIERYAMKFLEASLEEVSREELKQAE 2336
Query: 1543 EMTDEAVGD-SAEKPPTFASPETAPEVETSRTPPGESIKAAGKGRNNHRARNKRGSRARA 1601
E + A D K F P+ E P + G G HR K + R
Sbjct: 2337 EQVEAARKDLDQAKEEVFRLPQ-----EEEEGPGAGDESSCGTGGGTHRRSKKAKAPERP 2391
Query: 1602 SKDTSKLL 1609
S+ L
Sbjct: 2392 GTRVSERL 2399
Score = 31.6 bits (70), Expect = 9.2
Identities = 26/104 (25%), Positives = 47/104 (45%), Gaps = 13/104 (12%)
Query: 358 QFVDIHLEEDDSSDEEYQPDDEEEDETA------EESLLESDVESTASSPRGAKKSRLRQ 411
+ D+ LEE SS P++EEE + E++L ++ E + AK ++ +
Sbjct: 2208 ELFDMPLEEPSSSSVPSAPEEEEETVASKQTHILEQALCRAEDEEDIRAATQAKAEQVAE 2267
Query: 412 SSEMTETD-------EESGILSEAEKVTTPAIRHISAEVVPMGP 448
+E E D EE+G ++ + A + I+A V + P
Sbjct: 2268 LAEFNENDGFPAGEGEEAGRPGAEDEEMSRAEQEIAALVEQLTP 2311
>gi|55956788 nucleolin [Homo sapiens]
Length = 710
Score = 65.1 bits (157), Expect = 7e-10
Identities = 62/291 (21%), Positives = 118/291 (40%), Gaps = 28/291 (9%)
Query: 1316 PTPGDLEEIVKMEPEEAREEISGSPERDICDDIKVEHAVELDTG----APSEELSSAGEV 1371
P P ++EE + E EE S E + K + A +P+++++ A
Sbjct: 19 PPPKEVEEDSEDEEMSEDEEDDSSGEEVVIPQKKGKKAAATSAKKVVVSPTKKVAVATPA 78
Query: 1372 TKQTVLQKEEERSQPTK----------TPSSSQEPPDEGTSGTDVNKGSS---------K 1412
K V ++ + P K TP P + T KG++ K
Sbjct: 79 KKAAVTPGKKAAATPAKKTVTPAKAVTTPGKKGATPGKALVATPGKKGAAIPAKGAKNGK 138
Query: 1413 NALSS-MDPEVRLSSPPGKPEDSSSVDGQSVGTPVGPETGGEKNGPEEEEEEDFDDLTQD 1471
NA D E S + +D + + P + E+E++ED +D D
Sbjct: 139 NAKKEDSDEEEDDDSEEDEEDDEDEDEDEDEIEPAAMKAAAAAPASEDEDDEDDEDDEDD 198
Query: 1472 EEDEMSSASEESVLSVPELQETMEKLTWLASERRMSQEGESE-EENSQEENSEPEEEEEE 1530
++DE + EE++ + P + K+ + ++ E E E +E+ +++ E +E++++
Sbjct: 199 DDDEEDDSEEEAMETTPAKGKKAAKVVPVKAKNVAEDEDEEEDDEDEDDDDDEDDEDDDD 258
Query: 1531 EAEGMESLQKEDEMTDEAVGDSAEKPPTFASPETAPEVETSRTPPGESIKA 1581
E + E ++E+E EA G ++ A + APE + + E A
Sbjct: 259 EDDEEEEEEEEEEPVKEAPG---KRKKEMAKQKAAPEAKKQKVEGTEPTTA 306
Score = 42.4 bits (98), Expect = 0.005
Identities = 27/100 (27%), Positives = 50/100 (50%), Gaps = 2/100 (2%)
Query: 347 PIKKANEIKPPQFVDIHLEEDDSSDEEYQPDDEEEDETAEESLLESDVESTASSPRGAKK 406
P K A K + D EEDD S+E+ +D+E+++ E+ + + +++ A++P +
Sbjct: 130 PAKGAKNGKNAKKEDSDEEEDDDSEED--EEDDEDEDEDEDEIEPAAMKAAAAAPASEDE 187
Query: 407 SRLRQSSEMTETDEESGILSEAEKVTTPAIRHISAEVVPM 446
+ + D+E E TTPA +A+VVP+
Sbjct: 188 DDEDDEDDEDDDDDEEDDSEEEAMETTPAKGKKAAKVVPV 227
Score = 40.0 bits (92), Expect = 0.026
Identities = 70/316 (22%), Positives = 130/316 (41%), Gaps = 46/316 (14%)
Query: 366 EDDSSDEEYQPDDEEEDETAEESLL--ESDVESTASSPRGAKKSRLRQSSEMTETDEESG 423
E+DS DEE +DEE+D + EE ++ + ++ A+S + S ++ + T +++
Sbjct: 25 EEDSEDEEMS-EDEEDDSSGEEVVIPQKKGKKAAATSAKKVVVSPTKKVAVATPA-KKAA 82
Query: 424 ILSEAEKVTTPAIRHIS-AEVVPMGPPPPPKPKQTRDSTFMEKLHAVDEELASSPVCM-- 480
+ + TPA + ++ A+ V P + +T +K A+ + A +
Sbjct: 83 VTPGKKAAATPAKKTVTPAKAVTTPGKKGATPGKALVATPGKKGAAIPAKGAKNGKNAKK 142
Query: 481 -DSFQPMDDSLIAFRTRSKMPLKDVPLGQLE-AELQAPDITPDMYDPNTADDEDWKMWLG 538
DS + DD + +D ++E A ++A P D + DDED
Sbjct: 143 EDSDEEEDDD--SEEDEEDDEDEDEDEDEIEPAAMKAAAAAPASEDEDDEDDED------ 194
Query: 539 GLMNDDVGNEDEADDDDDPEYNFLEDLDEPDTEDFRTDRAVRITKKEV--NELMEELFET 596
DE DDDD+ + + E ++ + + + V + K V +E EE E
Sbjct: 195 ----------DEDDDDDEEDDSEEEAMETTPAKGKKAAKVVPVKAKNVAEDEDEEEDDED 244
Query: 597 FQDEMGFSNMEDDGPEEEECVAEPRPNFNTPQALRFEEPLANLLNEQHRTVKELFEQLKM 656
D+ + +DD ++EE E EEP+ ++ + E K
Sbjct: 245 EDDDDDEDDEDDDDEDDEEEEEEEE-----------EEPVKEAPGKRKK------EMAKQ 287
Query: 657 KKSSAKQLQEVEKVKP 672
K + + Q+VE +P
Sbjct: 288 KAAPEAKKQKVEGTEP 303
Score = 38.9 bits (89), Expect = 0.057
Identities = 21/69 (30%), Positives = 34/69 (49%), Gaps = 3/69 (4%)
Query: 345 ISPIKKANEIKPPQFVDIHLEEDDSSDEEYQPDDEEEDETAEESLLESDVESTASSPRGA 404
+ P+K N + + +EDD DE+ + DD+E+DE EE E + E +P
Sbjct: 224 VVPVKAKNVAEDEDEEEDDEDEDDDDDEDDEDDDDEDDEEEEE---EEEEEPVKEAPGKR 280
Query: 405 KKSRLRQSS 413
KK +Q +
Sbjct: 281 KKEMAKQKA 289
Score = 34.7 bits (78), Expect = 1.1
Identities = 20/75 (26%), Positives = 32/75 (42%)
Query: 1508 QEGESEEENSQEENSEPEEEEEEEAEGMESLQKEDEMTDEAVGDSAEKPPTFASPETAPE 1567
+E + EE+ +++ E E+E+E E M++ DE D + E E
Sbjct: 148 EEDDDSEEDEEDDEDEDEDEDEIEPAAMKAAAAAPASEDEDDEDDEDDEDDDDDEEDDSE 207
Query: 1568 VETSRTPPGESIKAA 1582
E T P + KAA
Sbjct: 208 EEAMETTPAKGKKAA 222
Score = 33.9 bits (76), Expect = 1.8
Identities = 18/78 (23%), Positives = 37/78 (47%), Gaps = 5/78 (6%)
Query: 349 KKANEIKPPQFVDIHLEEDDSSDEEYQPDDEEED-----ETAEESLLESDVESTASSPRG 403
KKA ++ P + ++ +ED+ D+E + DD++ED + +E E + E G
Sbjct: 219 KKAAKVVPVKAKNVAEDEDEEEDDEDEDDDDDEDDEDDDDEDDEEEEEEEEEEPVKEAPG 278
Query: 404 AKKSRLRQSSEMTETDEE 421
+K + + E ++
Sbjct: 279 KRKKEMAKQKAAPEAKKQ 296
Score = 32.0 bits (71), Expect = 7.0
Identities = 19/58 (32%), Positives = 31/58 (53%), Gaps = 5/58 (8%)
Query: 365 EEDDSSDEEYQPDDEEEDETAEESLLESDVEST-ASSPRGAKKSRLRQSSEMTETDEE 421
+EDD DE DDE++D+ E+ E +E+T A + AK ++ + + DEE
Sbjct: 186 DEDDEDDE----DDEDDDDDEEDDSEEEAMETTPAKGKKAAKVVPVKAKNVAEDEDEE 239
>gi|115648142 centrosomal protein 164kDa [Homo sapiens]
Length = 1460
Score = 62.0 bits (149), Expect = 6e-09
Identities = 82/332 (24%), Positives = 136/332 (40%), Gaps = 36/332 (10%)
Query: 1299 RQALEPL-------PQGIQESLNNPTPGDLEEIVKMEPEEAREEISGSPERDICDDIKVE 1351
RQA +PL Q Q+ L + LEE ++ P EE + SP R + + +
Sbjct: 438 RQAQQPLGIEDKDDSQSSQDELQSKQSKGLEE--RLSPPLPHEERAQSPPRSLATEEEPP 495
Query: 1352 HAVELDTGAP----SEELS--SAGEVTKQTVLQKEEERSQPT---KTPSSSQEPPDEGTS 1402
E G P +EEL SA ++ Q LQ+E+ S P K + + G
Sbjct: 496 QGPE---GQPEWKEAEELGEDSAASLSLQLSLQREQAPSPPAACEKGKEQHSQAEELGPG 552
Query: 1403 GTDVNKGSSKNALSS---MDPEVRLSSPPGKPEDSSSVDGQSVGTPVGPETGGEKNGPEE 1459
+ K A+S + PEVR + P PE S +++ V ++ E
Sbjct: 553 QEEAEDPEEKVAVSPTPPVSPEVRSTEPVAPPEQLSEAALKAMEEAVAQVLEQDQRHLLE 612
Query: 1460 EEEEDF----DDLTQDEEDEMSSASEESVLSVPELQETMEKLTWLASERRMSQEGESEEE 1515
++E + L Q+EE+E+ ++ S+ L+E ++K + E +E ES+
Sbjct: 613 SKQEKMQQLREKLCQEEEEEILRLHQQKEQSLSSLRERLQKA--IEEEEARMREEESQRL 670
Query: 1516 N---SQEENSEPEEEEEEEAEGMESLQK---EDEMTDEAVGDSAEKPPTFASPETAPEVE 1569
+ +Q ++S +E++ AE SLQK E E +A S E+ + E+E
Sbjct: 671 SWLRAQVQSSTQADEDQIRAEQEASLQKLREELESQQKAERASLEQKNRQMLEQLKEEIE 730
Query: 1570 TSRTPPGESIKAAGKGRNNHRARNKRGSRARA 1601
S ++ AA + G R A
Sbjct: 731 ASEKSEQAALNAAKEKALQQLREQLEGERKEA 762
Score = 43.9 bits (102), Expect = 0.002
Identities = 146/720 (20%), Positives = 259/720 (35%), Gaps = 117/720 (16%)
Query: 28 LESAVKPESDQVKDLSSVSLSWDPSHGRVAG---FEVQSLQDAGNQLGM------EDTSL 78
L V ++ SVSL GR G Q L+ + G+ + T+L
Sbjct: 150 LRGLVDTPPSALRGSQSVSLGSSVESGRQLGELMLPSQGLKTSAYTKGLLGSIYEDKTAL 209
Query: 79 SSGMLTQNTNVPILEGVDVAISQGITLPSLESFHPL-NIHIGKGKLHATGSKRGKKMTLR 137
S L + TN E D +Q + S PL N+H+ G L T +
Sbjct: 210 SLLGLGEETNEEDEEESD---NQSVH----SSSEPLRNLHLDIGALGGDFEYEESLRTSQ 262
Query: 138 PGPVTQEDRCDHLTLKEPFSGEPSE-EVKEEGGKPQMNSEGEIPSLPSGSQSAKPVSQPR 196
P E++ D ++L +G P+ + G ++S SG++ P +
Sbjct: 263 P-----EEKKD-VSLDSDAAGPPTPCKPSSPGADSSLSSAVGKGRQGSGARPGLPEKEEN 316
Query: 197 KSTQPDVC-------ASPQ-EKPLRTLFHQPEEEIEDGGLFIPMEEQDNEESEKRRKKKK 248
+ ++P +C A P +P + + E+ D G EE E + KKK
Sbjct: 317 EKSEPKICRNLVTPKADPTGSEPAKASEKEAPEDTVDAG-----EEGSRREEAAKEPKKK 371
Query: 249 GTKRKRDGR--GQEGTLAYDLKLDDMLDRTLEDGAKQHNLTAVNVRNILHEVITNEHVVA 306
+ + QE ++ +K + D D H L R+ + E + + V++
Sbjct: 372 ASALEEGSSDASQELEISEHMKEPQLSDSIASDPKSFHGLD-FGFRSRISEHLLDVDVLS 430
Query: 307 MMKAAISETEDMPMF-----EPKMTRSKLKEVVEKGVVIPTWNISPIKKANEIKPPQFVD 361
+ P+ + + ++ +L+ KG+ +SP E
Sbjct: 431 PVLGGACRQAQQPLGIEDKDDSQSSQDELQSKQSKGL---EERLSPPLPHEERAQSPPRS 487
Query: 362 IHLEEDDSSDEEYQPDDEEEDETAEESL------LESDVESTASSPRGAKKSRLR--QSS 413
+ EE+ E QP+ +E +E E+S L E S P +K + + Q+
Sbjct: 488 LATEEEPPQGPEGQPEWKEAEELGEDSAASLSLQLSLQREQAPSPPAACEKGKEQHSQAE 547
Query: 414 EMTETDEESGILSEAEKVTTPAIRHISAEVVPMGPPPPP--------------------- 452
E+ EE+ EKV +S EV P PP
Sbjct: 548 ELGPGQEEAE--DPEEKVAVSPTPPVSPEVRSTEPVAPPEQLSEAALKAMEEAVAQVLEQ 605
Query: 453 ------KPKQTRDSTFMEKLHAVDEELASSPVCMDSFQPMDDSLIAFRTRSKMPLKDVPL 506
+ KQ + EKL +EE + Q + SL + R R + +++
Sbjct: 606 DQRHLLESKQEKMQQLREKLCQEEEE-----EILRLHQQKEQSLSSLRERLQKAIEEEEA 660
Query: 507 GQLEAELQAPDITPDMYDPNTADDEDW----KMWLGGLMNDDVGNEDEADDDDDPEYN-- 560
E E Q +T DED + + +++ ++ +A+ + N
Sbjct: 661 RMREEESQRLSWLRAQVQSSTQADEDQIRAEQEASLQKLREELESQQKAERASLEQKNRQ 720
Query: 561 FLEDLDEPDTEDFRTDRAVRITKKEVNELMEELFETFQDEMGFSNMEDDGPEEEECVAEP 620
LE L E ++++A +N E+ + ++++ E E+E AE
Sbjct: 721 MLEQLKEEIEASEKSEQAA------LNAAKEKALQQLREQLEGERKEAVATLEKEHSAE- 773
Query: 621 RPNFNTPQALRFEEPLANLLNEQHRTVKELFEQLKMKKSSAKQLQEVEKVKPQSE-KVHQ 679
E L + L +HR V Q K++++ K+ +++K Q E +VHQ
Sbjct: 774 ------------LERLCSSLEAKHREVVSSL-QKKIQEAQQKEEAQLQKCLGQVEHRVHQ 820
Score = 38.5 bits (88), Expect = 0.075
Identities = 61/302 (20%), Positives = 123/302 (40%), Gaps = 23/302 (7%)
Query: 1248 KLEPQELSPLSATVFPKVEHSPGPPLADAECQEGLSENSACRWTVVKTEEGRQALEPLPQ 1307
+L + LS + + E +P PP A C++G ++S + EE E
Sbjct: 509 ELGEDSAASLSLQLSLQREQAPSPPAA---CEKGKEQHS-------QAEELGPGQEEAED 558
Query: 1308 GIQESLNNPTPGDLEEIVKMEPEEAREEISGSPERDICDDIKVEHAVELDTGAPSEELSS 1367
++ +PTP E+ EP E++S + + + + V +E D E
Sbjct: 559 PEEKVAVSPTPPVSPEVRSTEPVAPPEQLSEAALKAM--EEAVAQVLEQDQRHLLESKQE 616
Query: 1368 AGEVTKQTVLQKEEER-----SQPTKTPSSSQEPPDEGTSGTDVN-KGSSKNALSSMDPE 1421
+ ++ + Q+EEE Q ++ SS +E + + + LS + +
Sbjct: 617 KMQQLREKLCQEEEEEILRLHQQKEQSLSSLRERLQKAIEEEEARMREEESQRLSWLRAQ 676
Query: 1422 VRLSSPPGKPEDSSSVDG--QSVGTPVGPETGGEKNGPEEEEEEDFDDLTQDEEDEMSSA 1479
V+ S+ + + + + Q + + + E+ E++ + + L EE E S
Sbjct: 677 VQSSTQADEDQIRAEQEASLQKLREELESQQKAERASLEQKNRQMLEQLK--EEIEASEK 734
Query: 1480 SEESVLSVPELQETMEKLTWLASERRMSQEGESEEENSQEENSEPEEEEEEEAEGMESLQ 1539
SE++ L+ + ++ +++L R E+E+S E E + E + SLQ
Sbjct: 735 SEQAALNAAK-EKALQQLREQLEGERKEAVATLEKEHSAELERLCSSLEAKHREVVSSLQ 793
Query: 1540 KE 1541
K+
Sbjct: 794 KK 795
Score = 35.0 bits (79), Expect = 0.83
Identities = 41/198 (20%), Positives = 71/198 (35%), Gaps = 31/198 (15%)
Query: 1379 KEEERSQPTKTPSSSQEPP-----DEGTSGTDVNKGSSKNALS-------SMDPEVRLSS 1426
+E+E ++ SS EP D G G D S S+D +
Sbjct: 220 EEDEEESDNQSVHSSSEPLRNLHLDIGALGGDFEYEESLRTSQPEEKKDVSLDSDAAGPP 279
Query: 1427 PPGKPEDSSSVDGQSVGTPVGPETGGEKNGPEEEEEEDFDD-------LTQDEEDEMSSA 1479
P KP + S G + G + G E+EE + + +T + S
Sbjct: 280 TPCKPSSPGADSSLSSAVGKGRQGSGARPGLPEKEENEKSEPKICRNLVTPKADPTGSEP 339
Query: 1480 SEESVLSVPELQETMEKLTWLASERRMSQEGESEEENSQEENSEPEEEEEEEAEGMESLQ 1539
++ S PE +T++ +EG EE ++E + EE ++ + L+
Sbjct: 340 AKASEKEAPE--DTVD----------AGEEGSRREEAAKEPKKKASALEEGSSDASQELE 387
Query: 1540 KEDEMTDEAVGDSAEKPP 1557
+ M + + DS P
Sbjct: 388 ISEHMKEPQLSDSIASDP 405
Score = 32.0 bits (71), Expect = 7.0
Identities = 42/182 (23%), Positives = 70/182 (38%), Gaps = 18/182 (9%)
Query: 1802 GFEEVALPDVEEEEEPPKIPTASKNKRKK--EIGVQNHDKE------TEWPDGAKDCACS 1853
G E + EEE + + ++S+ R +IG D E T P+ KD +
Sbjct: 213 GLGEETNEEDEEESDNQSVHSSSEPLRNLHLDIGALGGDFEYEESLRTSQPEEKKDVSLD 272
Query: 1854 CHEGGPDSKLKKSKRRSCSHCSSKVCDSKSYKSKEPHELVGSSPHREASPM-------PG 1906
GP + K S + S SS V + P L + ++ P P
Sbjct: 273 SDAAGPPTPCKPSSPGADSSLSSAVGKGRQGSGARPG-LPEKEENEKSEPKICRNLVTPK 331
Query: 1907 AKEAG-QGKDMMEEEAPEERESTEATQSRTVRTTRKGEMPVSGLAVGSTLPSPREVTVTE 1965
A G + E+EAPE+ SR ++ + S L GS+ + +E+ ++E
Sbjct: 332 ADPTGSEPAKASEKEAPEDTVDAGEEGSRREEAAKEPKKKASALEEGSS-DASQELEISE 390
Query: 1966 RL 1967
+
Sbjct: 391 HM 392
>gi|212549782 caspase 8 associated protein 2 [Homo sapiens]
Length = 1982
Score = 61.6 bits (148), Expect = 8e-09
Identities = 47/145 (32%), Positives = 75/145 (51%), Gaps = 8/145 (5%)
Query: 2063 RRHVS--GKPDTQERWLPSSRARVKTRDRTCPVHESPSGIDTSETSPKAPRGGLAKDSGT 2120
RR++S P ++R + KT+ T E+ + KAP + KD +
Sbjct: 1836 RRNISDLNHPHKKQRKETDLTNKEKTKKPTQDSCENTEAHQKKASKKKAPP--VTKDPSS 1893
Query: 2121 QAKGPEGEQQPKAAEATVCANNSK--VSSTGEKVVLWTREADRVILTMCQEQGAQPQTFN 2178
K G + AA AT + ++K + GE ++LWTR DR IL CQ++G +TF
Sbjct: 1894 -LKATPGIKDSSAALATSTSLSAKNVIKKKGEIIILWTRNDDREILLECQKRGPSFKTFA 1952
Query: 2179 IISQQLGNKTPAEVSHRFRELMQLF 2203
++ +L +K P +VS RF++LM+LF
Sbjct: 1953 YLAAKL-DKNPNQVSERFQQLMKLF 1976
>gi|6912288 caspase 8 associated protein 2 [Homo sapiens]
Length = 1982
Score = 61.6 bits (148), Expect = 8e-09
Identities = 47/145 (32%), Positives = 75/145 (51%), Gaps = 8/145 (5%)
Query: 2063 RRHVS--GKPDTQERWLPSSRARVKTRDRTCPVHESPSGIDTSETSPKAPRGGLAKDSGT 2120
RR++S P ++R + KT+ T E+ + KAP + KD +
Sbjct: 1836 RRNISDLNHPHKKQRKETDLTNKEKTKKPTQDSCENTEAHQKKASKKKAPP--VTKDPSS 1893
Query: 2121 QAKGPEGEQQPKAAEATVCANNSK--VSSTGEKVVLWTREADRVILTMCQEQGAQPQTFN 2178
K G + AA AT + ++K + GE ++LWTR DR IL CQ++G +TF
Sbjct: 1894 -LKATPGIKDSSAALATSTSLSAKNVIKKKGEIIILWTRNDDREILLECQKRGPSFKTFA 1952
Query: 2179 IISQQLGNKTPAEVSHRFRELMQLF 2203
++ +L +K P +VS RF++LM+LF
Sbjct: 1953 YLAAKL-DKNPNQVSERFQQLMKLF 1976
>gi|212549532 caspase 8 associated protein 2 [Homo sapiens]
Length = 1982
Score = 61.6 bits (148), Expect = 8e-09
Identities = 47/145 (32%), Positives = 75/145 (51%), Gaps = 8/145 (5%)
Query: 2063 RRHVS--GKPDTQERWLPSSRARVKTRDRTCPVHESPSGIDTSETSPKAPRGGLAKDSGT 2120
RR++S P ++R + KT+ T E+ + KAP + KD +
Sbjct: 1836 RRNISDLNHPHKKQRKETDLTNKEKTKKPTQDSCENTEAHQKKASKKKAPP--VTKDPSS 1893
Query: 2121 QAKGPEGEQQPKAAEATVCANNSK--VSSTGEKVVLWTREADRVILTMCQEQGAQPQTFN 2178
K G + AA AT + ++K + GE ++LWTR DR IL CQ++G +TF
Sbjct: 1894 -LKATPGIKDSSAALATSTSLSAKNVIKKKGEIIILWTRNDDREILLECQKRGPSFKTFA 1952
Query: 2179 IISQQLGNKTPAEVSHRFRELMQLF 2203
++ +L +K P +VS RF++LM+LF
Sbjct: 1953 YLAAKL-DKNPNQVSERFQQLMKLF 1976
>gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens]
Length = 1020
Score = 59.7 bits (143), Expect = 3e-08
Identities = 119/557 (21%), Positives = 199/557 (35%), Gaps = 75/557 (13%)
Query: 1062 GGESFESPAALPAVPPEARTSFPLSESQTLLSSAPVPKVMLPSLAPSKFRKPYVRRRPSK 1121
G E +SP A A PE P+ E + A P+ + +P++ + P + P+K
Sbjct: 497 GEEETKSPPAEEAASPEKEAKSPVKEEAKSPAEAKSPE-KEEAKSPAEVKSPEKAKSPAK 555
Query: 1122 RRGVKASPCMKPAPVIHHPASVIFTVPATTVKIVSLGGGCNMIQPVNAAVAQSPQTI--P 1179
K P P PA VK + + A A+SP+ P
Sbjct: 556 EEA-------KSPPEAKSPEKEEAKSPA-EVKSPEKAKSPAKEEAKSPAEAKSPEKAKSP 607
Query: 1180 ITTLLVNPTSFPCPLNQSLVASSVSPLIVSGNSVNLPIPSTPEDKAHVNVDIACAVADGE 1239
+ +P P+ + + SP V +PE KA +
Sbjct: 608 VKEEAKSPAEAKSPVKE----EAKSPAEV----------KSPE-KAKSPTKEEAKSPEKA 652
Query: 1240 NAFQGLEPKLEPQELSPLSATVFPKVEHSPGPPLADAECQEGLSENSACRWTVVKTEEGR 1299
+ + E K + SP+ A E + P A+A+ E +E
Sbjct: 653 KSPEKEEAKSPEKAKSPVKAEA-KSPEKAKSPVKAEAKSPEKAKS---------PVKEEA 702
Query: 1300 QALEPLPQGIQESLNNP--TPGDLEEIVKMEPEEAR---EEISGSPERDICDDIKVEHAV 1354
++ E ++E +P ++E K PE+A+ +E + SPE+ E A
Sbjct: 703 KSPEKAKSPVKEEAKSPEKAKSPVKEEAK-TPEKAKSPVKEEAKSPEK----AKSPEKAK 757
Query: 1355 ELDTGAPSEELSSAGEVTKQTVLQKEEERSQPTKTPSSSQEPPDEGTSGTDVNKGSSKNA 1414
LD +P + + KEE RS K P ++ P E + K K
Sbjct: 758 TLDVKSPEAKTPA-----------KEEARSPADKFPEKAKSPVKEEVKSPEKAKSPLKED 806
Query: 1415 LSSMDPEVRLSSPPGKPEDSSSVDGQSVGTPVGPETGGEKNGPEEEEEEDFDDLTQDEED 1474
+ + E+ P K E S V + P+ K P++ EEE + EE
Sbjct: 807 AKAPEKEI-----PKKEEVKSPVKEEE-----KPQEVKVKEPPKKAEEEKAPATPKTEEK 856
Query: 1475 EMSSASEESVLSVPELQETMEKLTWLASERRMSQEGESEEENSQEENSEPEEEE------ 1528
+ S E P+ + +K + + E + EE +++ PE+E
Sbjct: 857 KDSKKEEAPKKEAPKPKVEEKKEPAVEKPKESKVEAKKEEAEDKKKVPTPEKEAPAKVEV 916
Query: 1529 EEEAEGMESLQKEDEMTDEAVGDSAEKP--PTFASPETAPEVETSRTPPGESIKAAGKGR 1586
+E+A+ E + + D+A KP A+PE E P E K K +
Sbjct: 917 KEDAKPKEKTEVAKKEPDDAKAKEPSKPAEKKEAAPEKKDTKEEKAKKPEEKPKTEAKAK 976
Query: 1587 NNHRARNKRGSRARASK 1603
+ + +K S+ +A K
Sbjct: 977 EDDKTLSKEPSKPKAEK 993
Score = 53.9 bits (128), Expect = 2e-06
Identities = 56/250 (22%), Positives = 101/250 (40%), Gaps = 20/250 (8%)
Query: 1363 EELSSAGEVTKQTVLQKEE-ERSQPTKTPSSSQEPPDEGTSGTDVNKGSSKNALSSMDPE 1421
E++ + K+TV+ +E+ E +Q T+ + +E + G + G + A E
Sbjct: 442 EKIKVVEKSEKETVIVEEQTEETQVTEEVTEEEEKEAKEEEGKEEEGGEEEEAEGG---E 498
Query: 1422 VRLSSPPGKPEDSSSVDGQSVGTPVGPETGGEKNGPEEEEEEDFDDLTQDEEDEMSSASE 1481
SPP + S + +S PV E E+EE ++ S ++
Sbjct: 499 EETKSPPAEEAASPEKEAKS---PVKEEAKSPAEAKSPEKEEAKSPAEVKSPEKAKSPAK 555
Query: 1482 ESVLSVPELQETMEKLTWLASERRMSQEGES---EEENSQEENSEPE-------EEEEEE 1531
E S PE + ++ +E + ++ +S EE S E PE EE +
Sbjct: 556 EEAKSPPEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPAEAKSPEKAKSPVKEEAKSP 615
Query: 1532 AEGMESLQKEDEMTDEAVGDSAEKPPTFASPETAPEVETSRTPPGESIKAAGKGRNNHRA 1591
AE +++E + E K PT E A E +++P E K+ K ++ +A
Sbjct: 616 AEAKSPVKEEAKSPAEVKSPEKAKSPT---KEEAKSPEKAKSPEKEEAKSPEKAKSPVKA 672
Query: 1592 RNKRGSRARA 1601
K +A++
Sbjct: 673 EAKSPEKAKS 682
Score = 51.6 bits (122), Expect = 9e-06
Identities = 127/622 (20%), Positives = 229/622 (36%), Gaps = 59/622 (9%)
Query: 91 ILEGVDVAISQG---ITLPS-LESFHPLNIHIG-KGKLHATGSKRGKKMTLRPGPVTQED 145
+LEG + I G +LP L ++ HI K + ++ +K T+ T+E
Sbjct: 405 LLEGEECRIGFGPIPFSLPEGLPKIPSVSTHIKVKSEEKIKVVEKSEKETVIVEEQTEET 464
Query: 146 RC-DHLTLKEPFSGEPSEEVKEEGGKPQMNSEGEIPSLPSGSQSAKPVSQPRKSTQPDVC 204
+ + +T +E + E +EEGG+ + GE + ++ A + KS +
Sbjct: 465 QVTEEVTEEEEKEAKEEEGKEEEGGEEEEAEGGEEETKSPPAEEAASPEKEAKSPVKEEA 524
Query: 205 ASPQE--KPLRTLFHQPEEEIEDGGLFIPMEEQDNEESEKRRKKK---------KGTKRK 253
SP E P + P E P +E+ E + +K K ++
Sbjct: 525 KSPAEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPPEAKSPEKEEAKSPAEVKSPEKA 584
Query: 254 RDGRGQEGTLAYDLKLDDMLDRTLEDGAKQHNLTAVNVRNILH---EVITNEHVVAMMK- 309
+ +E + K + +++ AK V+ EV + E + K
Sbjct: 585 KSPAKEEAKSPAEAKSPEKAKSPVKEEAKSPAEAKSPVKEEAKSPAEVKSPEKAKSPTKE 644
Query: 310 -AAISETEDMPMFEPKMTRSKLKEVVEKGVVIPTWNISPIKKANEIKPPQFVDIHLEEDD 368
A E P E + K K V+ P SP+K E K P+ ++E+
Sbjct: 645 EAKSPEKAKSPEKEEAKSPEKAKSPVKAEAKSPEKAKSPVKA--EAKSPEKAKSPVKEEA 702
Query: 369 SSDEEYQPDDEEEDETAEESLLESDVESTASSPRGAKKSRLRQSSEMTETDEESGILSEA 428
S E+ + +EE ++ E++ +S V+ A +P AK S + E +
Sbjct: 703 KSPEKAKSPVKEEAKSPEKA--KSPVKEEAKTPEKAK-------SPVKEEAKSPEKAKSP 753
Query: 429 EKVTTPAIRHISAEVVPMGPPPPPKPKQTRDSTFMEKLHAVDEELASSPVCMDSFQPMDD 488
EK T ++ A+ P K + K E A SP+ D+ P +
Sbjct: 754 EKAKTLDVKSPEAKTPAKEEARSPADKFPEKAKSPVKEEVKSPEKAKSPLKEDAKAP--E 811
Query: 489 SLIAFRTRSKMPLKDVPLGQLEAELQAPDITPDMYDPNTADDEDWKMWLGGLMNDDVGNE 548
I + K P+K+ Q + P + P T E+ K +
Sbjct: 812 KEIPKKEEVKSPVKEEEKPQEVKVKEPPKKAEEEKAPATPKTEEKK----------DSKK 861
Query: 549 DEADDDDDPEYNFLEDLDEPDTEDFRTDRAVRITKKEVNELMEELFETFQDEMGFSNMED 608
+EA + P+ +E+ EP E K +E E +D+ E
Sbjct: 862 EEAPKKEAPKPK-VEEKKEPAVE------------KPKESKVEAKKEEAEDKKKVPTPEK 908
Query: 609 DGPEEEECVAEPRPNFNTPQALRFEEPLANLLNEQHRTVKELFEQLK-MKKSSAKQLQEV 667
+ P + E + +P T A + + + KE + K K+ AK+ +E
Sbjct: 909 EAPAKVEVKEDAKPKEKTEVAKKEPDDAKAKEPSKPAEKKEAAPEKKDTKEEKAKKPEEK 968
Query: 668 EKVKPQSEKVHQTLILDPAQRK 689
K + ++++ +TL +P++ K
Sbjct: 969 PKTEAKAKEDDKTLSKEPSKPK 990
Score = 49.3 bits (116), Expect = 4e-05
Identities = 98/407 (24%), Positives = 154/407 (37%), Gaps = 45/407 (11%)
Query: 1745 LPQEITELKTQMWQLLKGHDHLQDEFSIFFDHLRPA--ASRMGDFEEINWTEEKEYEFDG 1802
+P T +K + + +K + + E I + + + EE EE+ E +G
Sbjct: 429 IPSVSTHIKVKSEEKIKVVEKSEKETVIVEEQTEETQVTEEVTEEEEKEAKEEEGKEEEG 488
Query: 1803 FEEVALPDVEEE-EEPPKIPTASKNKRKKEIGVQNHDKETEWPDGAKDCACSCHE-GGPD 1860
EE EEE + PP AS K K + E K+ A S E P+
Sbjct: 489 GEEEEAEGGEEETKSPPAEEAASPEKEAKSPVKEEAKSPAEAKSPEKEEAKSPAEVKSPE 548
Query: 1861 SKLKKSKRRSCSHCSSKVCDSKSYKS----KEPHELVGSSPHREASPMPG-AKEAGQGKD 1915
+K + S +K + + KS K P + SP +E + P AK + K
Sbjct: 549 KAKSPAKEEAKSPPEAKSPEKEEAKSPAEVKSPEK--AKSPAKEEAKSPAEAKSPEKAKS 606
Query: 1916 MMEEEA--PEERES---TEATQSRTVRTTRKGEMPVSGLAVGSTLPSPREVTVTERLLLD 1970
++EEA P E +S EA V++ K + P A SP + E+
Sbjct: 607 PVKEEAKSPAEAKSPVKEEAKSPAEVKSPEKAKSPTKEEA-----KSPEKAKSPEK---- 657
Query: 1971 GPPPHSPETPQFPPTTGAVLYTVKRNQVGPEVRSCPKA-SPRLQKEREGQKAVSESEALM 2029
SPE + P A ++ V E +S KA SP ++ + +KA S +
Sbjct: 658 -EEAKSPEKAKSPVKAEAKSPEKAKSPVKAEAKSPEKAKSPVKEEAKSPEKAKSPVKE-- 714
Query: 2030 LVWDASETEKLPGTV----EPPASFLSPVSSKTRDAGRRHVSGKPDTQERWLPSSRARVK 2085
+A EK V + P SPV + + + K T + P ++ K
Sbjct: 715 ---EAKSPEKAKSPVKEEAKTPEKAKSPVKEEAKSPEKAKSPEKAKTLDVKSPEAKTPAK 771
Query: 2086 TRDRTCPVHESP----SGIDTSETSPKAPRGGLAKDSGTQAKGPEGE 2128
R+ P + P S + SP+ + L +D AK PE E
Sbjct: 772 EEARS-PADKFPEKAKSPVKEEVKSPEKAKSPLKED----AKAPEKE 813
Score = 47.0 bits (110), Expect = 2e-04
Identities = 78/366 (21%), Positives = 143/366 (39%), Gaps = 50/366 (13%)
Query: 1804 EEVALPDVEEEEEPPKIPTASKNKRKKEIGVQNHDK-------ETEWPDGAKDCACSCHE 1856
E+ P EE + P + + K + K V++ +K E + P+ AK
Sbjct: 602 EKAKSPVKEEAKSPAEAKSPVKEEAKSPAEVKSPEKAKSPTKEEAKSPEKAKS------- 654
Query: 1857 GGPDSKLKKSKRRSCSHCSSKVCDSKSYKSKEPHELVGSSPHREASPM-PGAKEAGQGKD 1915
P+ + KS ++ S ++ + K+K P + SP + SP+ AK + K
Sbjct: 655 --PEKEEAKSPEKAKSPVKAEAKSPE--KAKSPVKAEAKSPEKAKSPVKEEAKSPEKAKS 710
Query: 1916 MMEEEAPEERESTEATQSRTVRTTRKGEMPVSGLAVGSTLPSPREVTVTERL-LLDGPPP 1974
++EEA + E ++ +T K + PV A SP + E+ LD P
Sbjct: 711 PVKEEA-KSPEKAKSPVKEEAKTPEKAKSPVKEEA-----KSPEKAKSPEKAKTLDVKSP 764
Query: 1975 HSPETPQFPPTTGAVLYTVK-RNQVGPEVRSCPKA-SPRLQKEREGQKAVSESEALMLVW 2032
+ + + A + K ++ V EV+S KA SP + + +K + + E +
Sbjct: 765 EAKTPAKEEARSPADKFPEKAKSPVKEEVKSPEKAKSPLKEDAKAPEKEIPKKEEVKSPV 824
Query: 2033 DASETEKLPGTVEPPASF---LSPVSSKT-------RDAGRRHVSGKPDTQERWLPS--- 2079
E + EPP +P + KT ++ + + KP +E+ P+
Sbjct: 825 KEEEKPQEVKVKEPPKKAEEEKAPATPKTEEKKDSKKEEAPKKEAPKPKVEEKKEPAVEK 884
Query: 2080 ---SRARVKTRDR------TCPVHESPSGIDTSETSPKAPRGGLAKDSGTQAKGPEGEQQ 2130
S+ K + P E+P+ ++ E + + +AK AK E +
Sbjct: 885 PKESKVEAKKEEAEDKKKVPTPEKEAPAKVEVKEDAKPKEKTEVAKKEPDDAKAKEPSKP 944
Query: 2131 PKAAEA 2136
+ EA
Sbjct: 945 AEKKEA 950
Score = 42.4 bits (98), Expect = 0.005
Identities = 45/212 (21%), Positives = 85/212 (40%), Gaps = 34/212 (16%)
Query: 1325 VKMEPEEAREEIS-GSPERDICDDIKVEHAVELDTGAPS--EELSSAGEVTKQTVLQ-KE 1380
VK P++A EE + +P+ + D K E A + + P E+ A E K++ ++ K+
Sbjct: 835 VKEPPKKAEEEKAPATPKTEEKKDSKKEEAPKKEAPKPKVEEKKEPAVEKPKESKVEAKK 894
Query: 1381 EERSQPTKTPSSSQEPPDEGTSGTDVNKGSSKNALSSMDPEVRLSSPPGKPEDSSSVDGQ 1440
EE K P+ +E P + D K K ++ +P+ + P KP +
Sbjct: 895 EEAEDKKKVPTPEKEAPAKVEVKEDA-KPKEKTEVAKKEPDDAKAKEPSKPAEKKE---- 949
Query: 1441 SVGTPVGPETGGEKNGPEEEEEEDFDDLTQDEEDEMSSASEESVLSVPELQETMEKLTWL 1500
PE K ++ EE + +ED+ + + E S
Sbjct: 950 -----AAPEKKDTKEEKAKKPEEKPKTEAKAKEDDKTLSKEPS----------------- 987
Query: 1501 ASERRMSQEGESEEENSQEENSEPEEEEEEEA 1532
+ +++ E Q+++ PE+ E++A
Sbjct: 988 ---KPKAEKAEKSSSTDQKDSKPPEKATEDKA 1016
Score = 39.3 bits (90), Expect = 0.044
Identities = 31/124 (25%), Positives = 55/124 (44%), Gaps = 5/124 (4%)
Query: 1480 SEESVLSVPELQETMEKLTWLASERRMSQEGESEEENSQEENSEPEEEE--EEEAEGMES 1537
SEE + V + ++ + E ++++E EEE +E EEE EEEAEG E
Sbjct: 440 SEEKIKVVEKSEKETVIVEEQTEETQVTEEVTEEEEKEAKEEEGKEEEGGEEEEAEGGEE 499
Query: 1538 LQKEDEMTDEAVGDSAEKPPTFASPETAPEVETSRTPPGESIKAAGKGRNNHRARNKRGS 1597
K + A + K P E A +++P E K+ + ++ +A++
Sbjct: 500 ETKSPPAEEAASPEKEAKSPV---KEEAKSPAEAKSPEKEEAKSPAEVKSPEKAKSPAKE 556
Query: 1598 RARA 1601
A++
Sbjct: 557 EAKS 560
>gi|94536805 splicing factor YT521-B isoform 2 [Homo sapiens]
Length = 709
Score = 59.7 bits (143), Expect = 3e-08
Identities = 57/201 (28%), Positives = 83/201 (41%), Gaps = 29/201 (14%)
Query: 1362 SEELSSAGEVTKQTVLQKEEERSQPTKTPSSSQEPPDEGTSGTDVNKGSSKNALSSMDPE 1421
++ L + ++ + +E ++QP KT ++P S T GS + L +D
Sbjct: 106 NKRLDADRKIRLSSSASREPYKNQPEKTCVRKRDPERRAKSPTP--DGSERIGLE-VDRR 162
Query: 1422 VRLSSPPGKPEDSSSVDGQSVGTPVGPETGGEKNGPEEEEEEDFDDLTQDEEDEMSSASE 1481
SS K E +S G T + + N E EEE +D+ +DEE E + +
Sbjct: 163 ASRSSQSSKEEVNSEEYGSDHETGSSGSSDEQGNNTENEEEGVEEDVEEDEEVEEDAEED 222
Query: 1482 ESVLSVPELQETMEKLTWLASERRMSQEGESEEENSQEENSEPEEEEEEEAEGMESLQKE 1541
E V ++GE EEE +EE E EEEEEEE E E QKE
Sbjct: 223 EEV----------------------DEDGEEEEEEEEEEEEE-EEEEEEEYEQDERDQKE 259
Query: 1542 ---DEMTDEAVGDSAEKPPTF 1559
D T DS + +F
Sbjct: 260 EGNDYDTRSEASDSGSESVSF 280
Score = 55.8 bits (133), Expect = 5e-07
Identities = 66/306 (21%), Positives = 123/306 (40%), Gaps = 29/306 (9%)
Query: 1309 IQESLNNPTPGDLEEIVKMEPEEAREEISGSP---ERDICDDIKVEHAVELDTGAPSEEL 1365
+ + + P +E+ E E+ + E GS +R D K + S+ L
Sbjct: 15 VLDDILTEVPEQDDELYNPESEQDKNEKKGSKRKSDRMESTDTKRQKPSVHSRQLVSKPL 74
Query: 1366 SSAGEVTKQTVLQK----------EEERSQPTKTPSSSQEPPDEGTSGTDVNKGS-SKNA 1414
SS+ K+ V K E +RS+ K + ++ ++ + K K
Sbjct: 75 SSSVSNNKRIVSTKGKSATEYKNEEYQRSERNKRLDADRKIRLSSSASREPYKNQPEKTC 134
Query: 1415 LSSMDPEVRLSSPPGKPEDSSSVDGQSVGTPVGPETGGEKNGPEEEEEEDFDDLTQDEED 1474
+ DPE R SP P+ S + +G V + ++ +EE + ++ D E
Sbjct: 135 VRKRDPERRAKSPT--PDGS-----ERIGLEV--DRRASRSSQSSKEEVNSEEYGSDHET 185
Query: 1475 EMSSASEESVLSVPELQETMEKLTWLASERRMSQEGESEEENSQEENSEPEEEEEEEAEG 1534
S +S+E + +E +E+ + +E E + E +E + + EEEEEEE E
Sbjct: 186 GSSGSSDEQGNNTENEEEGVEE------DVEEDEEVEEDAEEDEEVDEDGEEEEEEEEEE 239
Query: 1535 MESLQKEDEMTDEAVGDSAEKPPTFASPETAPEVETSRTPPGESIKAAGKGRNNHRARNK 1594
E ++E+E ++ D E+ + + A + + + +G G + + K
Sbjct: 240 EEEEEEEEEEYEQDERDQKEEGNDYDTRSEASDSGSESVSFTDGSVRSGSGTDGSDEKKK 299
Query: 1595 RGSRAR 1600
RAR
Sbjct: 300 ERKRAR 305
Score = 34.3 bits (77), Expect = 1.4
Identities = 22/77 (28%), Positives = 34/77 (44%), Gaps = 2/77 (2%)
Query: 361 DIHLEEDDSSDEEYQPDDEEEDETAEESLLESDVESTASSPRGAKKSRLRQSSEMTETDE 420
D +EED DEE D EEE+E EE E + E ++ + + ++ E
Sbjct: 212 DEEVEEDAEEDEEVDEDGEEEEEEEEEE--EEEEEEEEEEYEQDERDQKEEGNDYDTRSE 269
Query: 421 ESGILSEAEKVTTPAIR 437
S SE+ T ++R
Sbjct: 270 ASDSGSESVSFTDGSVR 286
>gi|72534750 splicing factor YT521-B isoform 1 [Homo sapiens]
Length = 727
Score = 59.7 bits (143), Expect = 3e-08
Identities = 57/201 (28%), Positives = 83/201 (41%), Gaps = 29/201 (14%)
Query: 1362 SEELSSAGEVTKQTVLQKEEERSQPTKTPSSSQEPPDEGTSGTDVNKGSSKNALSSMDPE 1421
++ L + ++ + +E ++QP KT ++P S T GS + L +D
Sbjct: 106 NKRLDADRKIRLSSSASREPYKNQPEKTCVRKRDPERRAKSPTP--DGSERIGLE-VDRR 162
Query: 1422 VRLSSPPGKPEDSSSVDGQSVGTPVGPETGGEKNGPEEEEEEDFDDLTQDEEDEMSSASE 1481
SS K E +S G T + + N E EEE +D+ +DEE E + +
Sbjct: 163 ASRSSQSSKEEVNSEEYGSDHETGSSGSSDEQGNNTENEEEGVEEDVEEDEEVEEDAEED 222
Query: 1482 ESVLSVPELQETMEKLTWLASERRMSQEGESEEENSQEENSEPEEEEEEEAEGMESLQKE 1541
E V ++GE EEE +EE E EEEEEEE E E QKE
Sbjct: 223 EEV----------------------DEDGEEEEEEEEEEEEE-EEEEEEEYEQDERDQKE 259
Query: 1542 ---DEMTDEAVGDSAEKPPTF 1559
D T DS + +F
Sbjct: 260 EGNDYDTRSEASDSGSESVSF 280
Score = 55.8 bits (133), Expect = 5e-07
Identities = 66/306 (21%), Positives = 123/306 (40%), Gaps = 29/306 (9%)
Query: 1309 IQESLNNPTPGDLEEIVKMEPEEAREEISGSP---ERDICDDIKVEHAVELDTGAPSEEL 1365
+ + + P +E+ E E+ + E GS +R D K + S+ L
Sbjct: 15 VLDDILTEVPEQDDELYNPESEQDKNEKKGSKRKSDRMESTDTKRQKPSVHSRQLVSKPL 74
Query: 1366 SSAGEVTKQTVLQK----------EEERSQPTKTPSSSQEPPDEGTSGTDVNKGS-SKNA 1414
SS+ K+ V K E +RS+ K + ++ ++ + K K
Sbjct: 75 SSSVSNNKRIVSTKGKSATEYKNEEYQRSERNKRLDADRKIRLSSSASREPYKNQPEKTC 134
Query: 1415 LSSMDPEVRLSSPPGKPEDSSSVDGQSVGTPVGPETGGEKNGPEEEEEEDFDDLTQDEED 1474
+ DPE R SP P+ S + +G V + ++ +EE + ++ D E
Sbjct: 135 VRKRDPERRAKSPT--PDGS-----ERIGLEV--DRRASRSSQSSKEEVNSEEYGSDHET 185
Query: 1475 EMSSASEESVLSVPELQETMEKLTWLASERRMSQEGESEEENSQEENSEPEEEEEEEAEG 1534
S +S+E + +E +E+ + +E E + E +E + + EEEEEEE E
Sbjct: 186 GSSGSSDEQGNNTENEEEGVEE------DVEEDEEVEEDAEEDEEVDEDGEEEEEEEEEE 239
Query: 1535 MESLQKEDEMTDEAVGDSAEKPPTFASPETAPEVETSRTPPGESIKAAGKGRNNHRARNK 1594
E ++E+E ++ D E+ + + A + + + +G G + + K
Sbjct: 240 EEEEEEEEEEYEQDERDQKEEGNDYDTRSEASDSGSESVSFTDGSVRSGSGTDGSDEKKK 299
Query: 1595 RGSRAR 1600
RAR
Sbjct: 300 ERKRAR 305
Score = 34.3 bits (77), Expect = 1.4
Identities = 22/77 (28%), Positives = 34/77 (44%), Gaps = 2/77 (2%)
Query: 361 DIHLEEDDSSDEEYQPDDEEEDETAEESLLESDVESTASSPRGAKKSRLRQSSEMTETDE 420
D +EED DEE D EEE+E EE E + E ++ + + ++ E
Sbjct: 212 DEEVEEDAEEDEEVDEDGEEEEEEEEEE--EEEEEEEEEEYEQDERDQKEEGNDYDTRSE 269
Query: 421 ESGILSEAEKVTTPAIR 437
S SE+ T ++R
Sbjct: 270 ASDSGSESVSFTDGSVR 286
>gi|157738649 neurofilament, medium polypeptide 150kDa isoform 1 [Homo
sapiens]
Length = 916
Score = 58.2 bits (139), Expect = 9e-08
Identities = 80/374 (21%), Positives = 145/374 (38%), Gaps = 19/374 (5%)
Query: 1246 EPKLEPQEL----SPLSATVFPKVEHSPGPPLADAECQEGLSENSACRWTVVKTEEG--- 1298
EP+ E +E+ SP+ AT P+V+ G + +E E+ + + EEG
Sbjct: 498 EPEAEEEEVAAKKSPVKATA-PEVKEEEGEKEEEEGQEEEEEEDEGAKSD--QAEEGGSE 554
Query: 1299 RQALEPLPQGIQESLNNPTPGDLEEIVKMEP---EEAREEISGSPERDICDDIKVEHAVE 1355
++ +G QE + EE E EE EE++ E + D KVE +
Sbjct: 555 KEGSSEKEEGEQEEGETEAEAEGEEAEAKEEKKVEEKSEEVATKEE--LVADAKVEKPEK 612
Query: 1356 LDTGAPSEELSSAGEVTKQTVLQKEEERSQPTKTPSSSQEPPDEGTSGTDVNKGSSKNAL 1415
+ P + G+ +E+ +S K+P + S + KG S +
Sbjct: 613 AKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVE-EKGKSPVSK 671
Query: 1416 SSMDPEVRLSSPPGKPEDSSSVDGQSVGTPVGPETGGEKNGPEEEEEEDFDDLTQDEEDE 1475
S ++ + + P E++ S G E K P+EE+ E ++ +D ++
Sbjct: 672 SPVEEKAKSPVPKSPVEEAKSKAEVGKGEQKEEEEKEVKEAPKEEKVEKKEEKPKDVPEK 731
Query: 1476 MSSASEESVLSVPELQETMEKLTWLASERRMSQEGE--SEEENSQEENSEPEEEEEEEAE 1533
+ S +V E+ T+ K + E+ +EG+ +E+ ++ E EEE +
Sbjct: 732 KKAESPVKEEAVAEVV-TITKSVKVHLEKETKEEGKPLQQEKEKEKAGGEGGSEEEGSDK 790
Query: 1534 GMESLQKEDEMTDEAVGDSAEKPPTFASPETAPEVETSRTPPGESIKAAGKGRNNHRARN 1593
G + +KED + V E + E E G + A + + ++
Sbjct: 791 GAKGSRKEDIAVNGEVEGKEEVEQETKEKGSGREEEKGVVTNGLDLSPADEKKGGDKSEE 850
Query: 1594 KRGSRARASKDTSK 1607
K K TS+
Sbjct: 851 KVVVTKTVEKITSE 864
Score = 50.4 bits (119), Expect = 2e-05
Identities = 56/224 (25%), Positives = 97/224 (43%), Gaps = 23/224 (10%)
Query: 1371 VTKQTVLQKEEERSQPTKTPSSSQEPPDEGTSGTDVNKGSSKNALSSMDPEVRLSSPPGK 1430
+T + +QK + + K E E T D K + AL+++ E+ +S K
Sbjct: 430 ITISSKIQKPKVEAPKLKVQHKFVEEIIEETKVED-EKSEMEEALTAITEELAVSMKEEK 488
Query: 1431 PE------DSSSVDGQSVGTPVGPETGGEKNGPEEEEEEDFDDLTQDEEDEMSSA-SEES 1483
E + + + V P EEE E++ ++ ++EE+E A S+++
Sbjct: 489 KEAAEEKEEEPEAEEEEVAAKKSPVKATAPEVKEEEGEKEEEEGQEEEEEEDEGAKSDQA 548
Query: 1484 VLSVPELQETMEKLTWLASERRMSQEGESEEENSQEENSEPEEEEEEEAEGMESLQKEDE 1543
E + + EK +EGE EE ++ E +E EE E +E + +E +E
Sbjct: 549 EEGGSEKEGSSEK-----------EEGEQEEGETEAE-AEGEEAEAKEEKKVEEKSEEVA 596
Query: 1544 MTDEAVGDS-AEKPPTFASP-ETAPEVETSRTP-PGESIKAAGK 1584
+E V D+ EKP SP +P E ++P P ++ GK
Sbjct: 597 TKEELVADAKVEKPEKAKSPVPKSPVEEKGKSPVPKSPVEEKGK 640
Score = 42.7 bits (99), Expect = 0.004
Identities = 72/308 (23%), Positives = 118/308 (38%), Gaps = 51/308 (16%)
Query: 152 LKEPFSGEPSEEVKEEGGKPQMNSEGEIPSLPSGSQSAKPVSQPRKSTQPDVCASPQEKP 211
+ E + EE KE + + E E + P K+T P+V EK
Sbjct: 476 ITEELAVSMKEEKKEAAEEKEEEPEAE-------EEEVAAKKSPVKATAPEVKEEEGEKE 528
Query: 212 LRTLFHQPEEEIEDGGLFIPMEEQDNEESEKRRKKKKGTKRKRDGRGQEGTLAYDLKLDD 271
Q EEE ED G ++++E+ +K+G+ K +G +EG + + +
Sbjct: 529 EEE--GQEEEEEEDEGA-------KSDQAEEGGSEKEGSSEKEEGEQEEGETEAEAEGE- 578
Query: 272 MLDRTLEDGAKQHNLTAVNVRNILHEVITNEHVVAMMKA-----AISETEDMPMFEPKMT 326
E AK+ V EV T E +VA K A S P+ E +
Sbjct: 579 ------EAEAKEEK----KVEEKSEEVATKEELVADAKVEKPEKAKSPVPKSPVEEKGKS 628
Query: 327 RSKLKEVVEKG-VVIPTWNISPIKKANEIKPPQFVDIHLEEDDSSDEEYQPDDEEEDETA 385
V EKG +P SP+++ + P+ +EE S P +E+
Sbjct: 629 PVPKSPVEEKGKSPVPK---SPVEEKGKSPVPK---SPVEEKGKSPVSKSPVEEKAKSPV 682
Query: 386 EESLLESDVESTASSPRGAKKSRLRQSSEMTETDEESGI---------LSEAEKVTTPAI 436
+S +E + +S A +G +K + E+ E +E + + E +K +P
Sbjct: 683 PKSPVE-EAKSKAEVGKGEQKE--EEEKEVKEAPKEEKVEKKEEKPKDVPEKKKAESPVK 739
Query: 437 RHISAEVV 444
AEVV
Sbjct: 740 EEAVAEVV 747
Score = 42.7 bits (99), Expect = 0.004
Identities = 61/245 (24%), Positives = 98/245 (40%), Gaps = 54/245 (22%)
Query: 299 ITNEHVVAMM---KAAISETEDMPMFEPKMTRSKLKEVVEKGVVIPTWNISPIKK-ANEI 354
IT E V+M K A E E+ P E + +K SP+K A E+
Sbjct: 476 ITEELAVSMKEEKKEAAEEKEEEPEAEEEEVAAKK---------------SPVKATAPEV 520
Query: 355 KPPQFVDIHLEEDDSSDEEYQPDDEEEDETAEESLLE---SDVESTASSPRGAK---KSR 408
K EE + +EE Q ++EEEDE A+ E S+ E ++ G + ++
Sbjct: 521 KE--------EEGEKEEEEGQEEEEEEDEGAKSDQAEEGGSEKEGSSEKEEGEQEEGETE 572
Query: 409 LRQSSEMTETDEESGILSEAEKVTTPAIRHISAEV---------VPMGP-------PPPP 452
E E EE + ++E+V T A+V VP P P P
Sbjct: 573 AEAEGEEAEAKEEKKVEEKSEEVATKEELVADAKVEKPEKAKSPVPKSPVEEKGKSPVPK 632
Query: 453 KPKQTRDSTFMEKLHAVDEE----LASSPVCMDSFQPMDDSLIAFRTRSKMPLKDVPLGQ 508
P + + + + K V+E+ + SPV P+ S + + +S +P V +
Sbjct: 633 SPVEEKGKSPVPK-SPVEEKGKSPVPKSPVEEKGKSPVSKSPVEEKAKSPVPKSPVEEAK 691
Query: 509 LEAEL 513
+AE+
Sbjct: 692 SKAEV 696
Score = 42.7 bits (99), Expect = 0.004
Identities = 44/168 (26%), Positives = 68/168 (40%), Gaps = 8/168 (4%)
Query: 1794 EEKEYEFDGFEEVALPDVEEEEEPPKIPTASKNKRKKEIGVQNHDKETEWPDGAKDCACS 1853
E KE E + EE + EEE+E K A + +KE + + E E +G +
Sbjct: 519 EVKEEEGEKEEEEGQEEEEEEDEGAKSDQAEEGGSEKEGSSEKEEGEQE--EGETEAEAE 576
Query: 1854 CHEG-GPDSKLKKSKRRSCSHCSSKVCDSKSYKSKEPHELVGSSPHRE--ASPMPGAKEA 1910
E + K + K + V D+K K ++ V SP E SP+P +
Sbjct: 577 GEEAEAKEEKKVEEKSEEVATKEELVADAKVEKPEKAKSPVPKSPVEEKGKSPVPKSPVE 636
Query: 1911 GQGKDMMEEEAPEERESTEATQSRTVRTTRKGEMPVSGLAVGSTLPSP 1958
+GK + + EE+ + +S KG+ PVS V SP
Sbjct: 637 EKGKSPVPKSPVEEKGKSPVPKS---PVEEKGKSPVSKSPVEEKAKSP 681
Score = 32.3 bits (72), Expect = 5.4
Identities = 56/196 (28%), Positives = 76/196 (38%), Gaps = 28/196 (14%)
Query: 1794 EEKEYEFDGFEEVALPDVEEEEEPPKIPTASKNKRKKEIGVQNHDKETEWPDGAKD-CAC 1852
EE E E E A + E +E K+ S+ KE V D + E P+ AK
Sbjct: 562 EEGEQEEGETEAEAEGEEAEAKEEKKVEEKSEEVATKEELVA--DAKVEKPEKAKSPVPK 619
Query: 1853 SCHEGGPDSKLKKS----KRRSCSHCSSKVCDSKSYKSKEPHELVGSSP-------HREA 1901
S E S + KS K +S S KS K P E G SP +
Sbjct: 620 SPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVSKSPVEEKAK 679
Query: 1902 SPMPGAK--------EAGQGKDMMEEE-----AP-EERESTEATQSRTVRTTRKGEMPVS 1947
SP+P + E G+G+ EEE AP EE+ + + + V +K E PV
Sbjct: 680 SPVPKSPVEEAKSKAEVGKGEQKEEEEKEVKEAPKEEKVEKKEEKPKDVPEKKKAESPVK 739
Query: 1948 GLAVGSTLPSPREVTV 1963
AV + + V V
Sbjct: 740 EEAVAEVVTITKSVKV 755
>gi|157738641 neurofilament, medium polypeptide 150kDa isoform 2 [Homo
sapiens]
Length = 540
Score = 58.2 bits (139), Expect = 9e-08
Identities = 80/374 (21%), Positives = 145/374 (38%), Gaps = 19/374 (5%)
Query: 1246 EPKLEPQEL----SPLSATVFPKVEHSPGPPLADAECQEGLSENSACRWTVVKTEEG--- 1298
EP+ E +E+ SP+ AT P+V+ G + +E E+ + + EEG
Sbjct: 122 EPEAEEEEVAAKKSPVKATA-PEVKEEEGEKEEEEGQEEEEEEDEGAKSD--QAEEGGSE 178
Query: 1299 RQALEPLPQGIQESLNNPTPGDLEEIVKMEP---EEAREEISGSPERDICDDIKVEHAVE 1355
++ +G QE + EE E EE EE++ E + D KVE +
Sbjct: 179 KEGSSEKEEGEQEEGETEAEAEGEEAEAKEEKKVEEKSEEVATKEE--LVADAKVEKPEK 236
Query: 1356 LDTGAPSEELSSAGEVTKQTVLQKEEERSQPTKTPSSSQEPPDEGTSGTDVNKGSSKNAL 1415
+ P + G+ +E+ +S K+P + S + KG S +
Sbjct: 237 AKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVE-EKGKSPVSK 295
Query: 1416 SSMDPEVRLSSPPGKPEDSSSVDGQSVGTPVGPETGGEKNGPEEEEEEDFDDLTQDEEDE 1475
S ++ + + P E++ S G E K P+EE+ E ++ +D ++
Sbjct: 296 SPVEEKAKSPVPKSPVEEAKSKAEVGKGEQKEEEEKEVKEAPKEEKVEKKEEKPKDVPEK 355
Query: 1476 MSSASEESVLSVPELQETMEKLTWLASERRMSQEGE--SEEENSQEENSEPEEEEEEEAE 1533
+ S +V E+ T+ K + E+ +EG+ +E+ ++ E EEE +
Sbjct: 356 KKAESPVKEEAVAEVV-TITKSVKVHLEKETKEEGKPLQQEKEKEKAGGEGGSEEEGSDK 414
Query: 1534 GMESLQKEDEMTDEAVGDSAEKPPTFASPETAPEVETSRTPPGESIKAAGKGRNNHRARN 1593
G + +KED + V E + E E G + A + + ++
Sbjct: 415 GAKGSRKEDIAVNGEVEGKEEVEQETKEKGSGREEEKGVVTNGLDLSPADEKKGGDKSEE 474
Query: 1594 KRGSRARASKDTSK 1607
K K TS+
Sbjct: 475 KVVVTKTVEKITSE 488
Score = 50.4 bits (119), Expect = 2e-05
Identities = 56/224 (25%), Positives = 97/224 (43%), Gaps = 23/224 (10%)
Query: 1371 VTKQTVLQKEEERSQPTKTPSSSQEPPDEGTSGTDVNKGSSKNALSSMDPEVRLSSPPGK 1430
+T + +QK + + K E E T D K + AL+++ E+ +S K
Sbjct: 54 ITISSKIQKPKVEAPKLKVQHKFVEEIIEETKVED-EKSEMEEALTAITEELAVSMKEEK 112
Query: 1431 PE------DSSSVDGQSVGTPVGPETGGEKNGPEEEEEEDFDDLTQDEEDEMSSA-SEES 1483
E + + + V P EEE E++ ++ ++EE+E A S+++
Sbjct: 113 KEAAEEKEEEPEAEEEEVAAKKSPVKATAPEVKEEEGEKEEEEGQEEEEEEDEGAKSDQA 172
Query: 1484 VLSVPELQETMEKLTWLASERRMSQEGESEEENSQEENSEPEEEEEEEAEGMESLQKEDE 1543
E + + EK +EGE EE ++ E +E EE E +E + +E +E
Sbjct: 173 EEGGSEKEGSSEK-----------EEGEQEEGETEAE-AEGEEAEAKEEKKVEEKSEEVA 220
Query: 1544 MTDEAVGDS-AEKPPTFASP-ETAPEVETSRTP-PGESIKAAGK 1584
+E V D+ EKP SP +P E ++P P ++ GK
Sbjct: 221 TKEELVADAKVEKPEKAKSPVPKSPVEEKGKSPVPKSPVEEKGK 264
Score = 42.7 bits (99), Expect = 0.004
Identities = 72/308 (23%), Positives = 118/308 (38%), Gaps = 51/308 (16%)
Query: 152 LKEPFSGEPSEEVKEEGGKPQMNSEGEIPSLPSGSQSAKPVSQPRKSTQPDVCASPQEKP 211
+ E + EE KE + + E E + P K+T P+V EK
Sbjct: 100 ITEELAVSMKEEKKEAAEEKEEEPEAE-------EEEVAAKKSPVKATAPEVKEEEGEKE 152
Query: 212 LRTLFHQPEEEIEDGGLFIPMEEQDNEESEKRRKKKKGTKRKRDGRGQEGTLAYDLKLDD 271
Q EEE ED G ++++E+ +K+G+ K +G +EG + + +
Sbjct: 153 EEE--GQEEEEEEDEGA-------KSDQAEEGGSEKEGSSEKEEGEQEEGETEAEAEGE- 202
Query: 272 MLDRTLEDGAKQHNLTAVNVRNILHEVITNEHVVAMMKA-----AISETEDMPMFEPKMT 326
E AK+ V EV T E +VA K A S P+ E +
Sbjct: 203 ------EAEAKEEK----KVEEKSEEVATKEELVADAKVEKPEKAKSPVPKSPVEEKGKS 252
Query: 327 RSKLKEVVEKG-VVIPTWNISPIKKANEIKPPQFVDIHLEEDDSSDEEYQPDDEEEDETA 385
V EKG +P SP+++ + P+ +EE S P +E+
Sbjct: 253 PVPKSPVEEKGKSPVPK---SPVEEKGKSPVPK---SPVEEKGKSPVSKSPVEEKAKSPV 306
Query: 386 EESLLESDVESTASSPRGAKKSRLRQSSEMTETDEESGI---------LSEAEKVTTPAI 436
+S +E + +S A +G +K + E+ E +E + + E +K +P
Sbjct: 307 PKSPVE-EAKSKAEVGKGEQKE--EEEKEVKEAPKEEKVEKKEEKPKDVPEKKKAESPVK 363
Query: 437 RHISAEVV 444
AEVV
Sbjct: 364 EEAVAEVV 371
Score = 42.7 bits (99), Expect = 0.004
Identities = 61/245 (24%), Positives = 98/245 (40%), Gaps = 54/245 (22%)
Query: 299 ITNEHVVAMM---KAAISETEDMPMFEPKMTRSKLKEVVEKGVVIPTWNISPIKK-ANEI 354
IT E V+M K A E E+ P E + +K SP+K A E+
Sbjct: 100 ITEELAVSMKEEKKEAAEEKEEEPEAEEEEVAAKK---------------SPVKATAPEV 144
Query: 355 KPPQFVDIHLEEDDSSDEEYQPDDEEEDETAEESLLE---SDVESTASSPRGAK---KSR 408
K EE + +EE Q ++EEEDE A+ E S+ E ++ G + ++
Sbjct: 145 KE--------EEGEKEEEEGQEEEEEEDEGAKSDQAEEGGSEKEGSSEKEEGEQEEGETE 196
Query: 409 LRQSSEMTETDEESGILSEAEKVTTPAIRHISAEV---------VPMGP-------PPPP 452
E E EE + ++E+V T A+V VP P P P
Sbjct: 197 AEAEGEEAEAKEEKKVEEKSEEVATKEELVADAKVEKPEKAKSPVPKSPVEEKGKSPVPK 256
Query: 453 KPKQTRDSTFMEKLHAVDEE----LASSPVCMDSFQPMDDSLIAFRTRSKMPLKDVPLGQ 508
P + + + + K V+E+ + SPV P+ S + + +S +P V +
Sbjct: 257 SPVEEKGKSPVPK-SPVEEKGKSPVPKSPVEEKGKSPVSKSPVEEKAKSPVPKSPVEEAK 315
Query: 509 LEAEL 513
+AE+
Sbjct: 316 SKAEV 320
Score = 42.7 bits (99), Expect = 0.004
Identities = 44/168 (26%), Positives = 68/168 (40%), Gaps = 8/168 (4%)
Query: 1794 EEKEYEFDGFEEVALPDVEEEEEPPKIPTASKNKRKKEIGVQNHDKETEWPDGAKDCACS 1853
E KE E + EE + EEE+E K A + +KE + + E E +G +
Sbjct: 143 EVKEEEGEKEEEEGQEEEEEEDEGAKSDQAEEGGSEKEGSSEKEEGEQE--EGETEAEAE 200
Query: 1854 CHEG-GPDSKLKKSKRRSCSHCSSKVCDSKSYKSKEPHELVGSSPHRE--ASPMPGAKEA 1910
E + K + K + V D+K K ++ V SP E SP+P +
Sbjct: 201 GEEAEAKEEKKVEEKSEEVATKEELVADAKVEKPEKAKSPVPKSPVEEKGKSPVPKSPVE 260
Query: 1911 GQGKDMMEEEAPEERESTEATQSRTVRTTRKGEMPVSGLAVGSTLPSP 1958
+GK + + EE+ + +S KG+ PVS V SP
Sbjct: 261 EKGKSPVPKSPVEEKGKSPVPKS---PVEEKGKSPVSKSPVEEKAKSP 305
Score = 32.3 bits (72), Expect = 5.4
Identities = 56/196 (28%), Positives = 76/196 (38%), Gaps = 28/196 (14%)
Query: 1794 EEKEYEFDGFEEVALPDVEEEEEPPKIPTASKNKRKKEIGVQNHDKETEWPDGAKD-CAC 1852
EE E E E A + E +E K+ S+ KE V D + E P+ AK
Sbjct: 186 EEGEQEEGETEAEAEGEEAEAKEEKKVEEKSEEVATKEELVA--DAKVEKPEKAKSPVPK 243
Query: 1853 SCHEGGPDSKLKKS----KRRSCSHCSSKVCDSKSYKSKEPHELVGSSP-------HREA 1901
S E S + KS K +S S KS K P E G SP +
Sbjct: 244 SPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVSKSPVEEKAK 303
Query: 1902 SPMPGAK--------EAGQGKDMMEEE-----AP-EERESTEATQSRTVRTTRKGEMPVS 1947
SP+P + E G+G+ EEE AP EE+ + + + V +K E PV
Sbjct: 304 SPVPKSPVEEAKSKAEVGKGEQKEEEEKEVKEAPKEEKVEKKEEKPKDVPEKKKAESPVK 363
Query: 1948 GLAVGSTLPSPREVTV 1963
AV + + V V
Sbjct: 364 EEAVAEVVTITKSVKV 379
>gi|155030232 proline, glutamic acid and leucine rich protein 1 [Homo
sapiens]
Length = 1130
Score = 57.4 bits (137), Expect = 2e-07
Identities = 49/173 (28%), Positives = 71/173 (41%), Gaps = 34/173 (19%)
Query: 1427 PPGKPEDSSSVDGQSVGTPVGPETGGEKNGPEEEEEEDFDDLTQDEEDEMSSASEESVLS 1486
PP ED + ++ S + E E+ EEEEEE+ +D ++EEDE EE
Sbjct: 871 PPALEEDLTVININS--SDEEEEEEEEEEEEEEEEEEEEEDFEEEEEDEEEYFEEEE--- 925
Query: 1487 VPELQETMEKLTWLASERRMSQEGESEEENSQEENSEPEEEEEEEAEGMESLQKEDEMTD 1546
E E E EEE + E E EE+EEEE E L++ +++
Sbjct: 926 ----------------EEEEEFEEEFEEEEGELEEEEEEEDEEEE----EELEEVEDLEF 965
Query: 1547 EAVGDSAEK--------PPTFASPETAPEVETSRTP-PGESIKAAGKGRNNHR 1590
G E+ PP PE+ P+V+ P PG ++ G R
Sbjct: 966 GTAGGEVEEGAPPPPTLPPALPPPESPPKVQPEPEPEPGLLLEVEEPGTEEER 1018
Score = 51.2 bits (121), Expect = 1e-05
Identities = 129/541 (23%), Positives = 185/541 (34%), Gaps = 62/541 (11%)
Query: 1051 TVPGVPPLGVSGGESFESPAALPAVPPEARTSFPLSESQTLLSSAPVPKV-MLPSLAP-- 1107
T P VPPL G P P PPEA + F + P+P V +PS P
Sbjct: 631 THPRVPPLQPMGPTC---PTPAPVPPPEAPSPF---RAPPFHPPGPMPSVGSMPSAGPMP 684
Query: 1108 SKFRKPYVRRRPSKRRGVKASPCMKPAPVIHHPASV--IFTVPATTVKIVSLGGGCNMIQ 1165
S P PS R G P H SV + +VP + +
Sbjct: 685 SAGPMPSAGPVPSARPG-------PPTTANHLGLSVPGLVSVPPRLLPGPENHRAGSNED 737
Query: 1166 PVNAAVAQSPQTIPITTLLVNPTSFPCPLNQSLVASSVSPLIVSGNS----VNLP--IPS 1219
P+ A P TIP P ++ +S + + +S V +P +P
Sbjct: 738 PILAPSGTPPPTIPPDETFGGRVPRPAFVHYDKEEASDVEISLESDSDDSVVIVPEGLPP 797
Query: 1220 TPEDKAHVNVDIACAVADGENAFQGLEPKLEPQELSPLSATVFPKVEHSPGPPLADAECQ 1279
P A A + K EP+EL + P P PP
Sbjct: 798 LPPPPPSGATPPPIAPTGPPTASPPVPAKEEPEELPAAPGPLPP-----PPPPPPPVPGP 852
Query: 1280 EGLSENSACRWTVVKTEEGRQALEPLPQGIQESLN--NPTPGDLEEIVKMEPEEAREEIS 1337
L V + G P ++E L N D EE + E EE EE
Sbjct: 853 VTLPPPQL----VPEGTPGGGG----PPALEEDLTVININSSDEEEEEEEEEEEEEEE-E 903
Query: 1338 GSPERDICDDIKVEHAVELDTGAPSEELSSAGEVTKQTVLQKEEERSQPTKTPSSSQEPP 1397
E D ++ + E + EE E + + ++EEE + + E
Sbjct: 904 EEEEEDFEEEEEDEEEYFEEEEEEEEEFEEEFEEEEGELEEEEEEEDEEEEEELEEVEDL 963
Query: 1398 DEGTSGTDVNKGSSKNALSSMDPEVRLSSPPGKPEDSSSVDGQSVGTPVGPETG--GEKN 1455
+ GT+G +V +G+ P + + PP PE V + PE G E
Sbjct: 964 EFGTAGGEVEEGAPP------PPTLPPALPP--PESPPKVQPEP-----EPEPGLLLEVE 1010
Query: 1456 GPEEEEEEDFDDLTQDEEDEMSSASE-----ESVLSVPELQETMEKLTWLASERRMSQEG 1510
P EEE D + + S E ES + P QE +E+ A + +E
Sbjct: 1011 EPGTEEERGADTAPTLAPEALPSQGEVEREGESPAAGPPPQELVEEEP-SAPPTLLEEET 1069
Query: 1511 ESEEENSQEENSEPEEEEEEEAEGMESLQ-KEDEMTDEAVGDSAEKPPTFASPETAPEVE 1569
E + Q P EEE E E+LQ KE + T + D + PP P E +
Sbjct: 1070 EDGSDKVQPPPETPAEEEMETETEAEALQEKEQDDTAAMLADFIDCPPDDEKPPPPTEPD 1129
Query: 1570 T 1570
+
Sbjct: 1130 S 1130
Score = 40.4 bits (93), Expect = 0.020
Identities = 27/90 (30%), Positives = 38/90 (42%), Gaps = 3/90 (3%)
Query: 365 EEDDSSDEEYQPDDEEEDETAEESLLESDVESTASSPRGAKKSRLRQSSEMTETDEESGI 424
EE++ +EE + D EEE+E EE E + E ++ + E E +EE
Sbjct: 897 EEEEEEEEEEEEDFEEEEEDEEEYFEEEEEEEEEFEEEFEEEEGELEEEEEEEDEEEE-- 954
Query: 425 LSEAEKVTTPAIRHISAEVVPMGPPPPPKP 454
E E+V EV PPPP P
Sbjct: 955 -EELEEVEDLEFGTAGGEVEEGAPPPPTLP 983
Score = 39.7 bits (91), Expect = 0.034
Identities = 34/107 (31%), Positives = 43/107 (40%), Gaps = 18/107 (16%)
Query: 364 LEED------DSSDEEYQPDDEEEDETAEESLLESDVESTASSPRGAKKSRLRQSSEMTE 417
LEED +SSDEE + ++EEE+E EE E D E + + E E
Sbjct: 874 LEEDLTVININSSDEEEEEEEEEEEEEEEEEEEEEDFEEEEEDEEEYFEEEEEEEEEFEE 933
Query: 418 T-DEESGILSEAEKVTTPAIRHISAEV-----------VPMGPPPPP 452
+EE G L E E+ EV V G PPPP
Sbjct: 934 EFEEEEGELEEEEEEEDEEEEEELEEVEDLEFGTAGGEVEEGAPPPP 980
Score = 36.6 bits (83), Expect = 0.28
Identities = 59/241 (24%), Positives = 95/241 (39%), Gaps = 29/241 (12%)
Query: 220 EEEIEDGGLFIPMEEQDNEESEKRRKKKKGTKRKRDGRGQEGTLAYDLKLDDMLDRTLED 279
EEE ED + EE++ EE E+ ++++G + + E + +L+++ D LE
Sbjct: 911 EEEEEDEEEYFEEEEEEEEEFEEEFEEEEGELEEEEEEEDEEE---EEELEEVED--LEF 965
Query: 280 GAKQHNLTAVNVRNILHEVITNEHVVAMMKAAISETEDMPMF--EPKMTRSKLKEVVEKG 337
G EV + A+ E P EP+ L EV E G
Sbjct: 966 GTAGG------------EVEEGAPPPPTLPPALPPPESPPKVQPEPEPEPGLLLEVEEPG 1013
Query: 338 VVIPTWNISPIKKANEIKPPQFVDIHLEEDDSSDEEYQPDDE--EEDETAEESLLESDVE 395
+ A E P Q +E + S P E EE+ +A +LLE + E
Sbjct: 1014 TEEERGADTAPTLAPEALPSQG---EVEREGESPAAGPPPQELVEEEPSAPPTLLEEETE 1070
Query: 396 STASSPRGAKKSRLRQSSEMTETDEESGILSEAEKVTTPAIRHISAEVVP--MGPPPPPK 453
+ + ++ + E ET+ E+ L E E+ T A+ + P PPPP +
Sbjct: 1071 DGSDKVQPPPET---PAEEEMETETEAEALQEKEQDDTAAMLADFIDCPPDDEKPPPPTE 1127
Query: 454 P 454
P
Sbjct: 1128 P 1128
Score = 35.0 bits (79), Expect = 0.83
Identities = 22/77 (28%), Positives = 40/77 (51%), Gaps = 1/77 (1%)
Query: 540 LMNDDVGNEDEADDDDDPEYNFLEDLDEPDTEDFRTDRAVRITKKEVNEL-MEELFETFQ 598
++N + +E+E +++++ E E+ +E D E+ D ++E E EE FE +
Sbjct: 880 VININSSDEEEEEEEEEEEEEEEEEEEEEDFEEEEEDEEEYFEEEEEEEEEFEEEFEEEE 939
Query: 599 DEMGFSNMEDDGPEEEE 615
E+ E+D EEEE
Sbjct: 940 GELEEEEEEEDEEEEEE 956
>gi|58761548 tau tubulin kinase 1 [Homo sapiens]
Length = 1321
Score = 57.4 bits (137), Expect = 2e-07
Identities = 85/385 (22%), Positives = 134/385 (34%), Gaps = 91/385 (23%)
Query: 1325 VKMEPEEAREEISGSPERDICDD-------IKVEHA-------VELDTGAPSEELSSAGE 1370
V++ +R ++ GSP R C + HA +++ E LS+A
Sbjct: 469 VELPERRSRMDLPGSPSRQACSSQPAQMLSVDTGHADRQASGRMDVSASVEQEALSNAFR 528
Query: 1371 -----------------VTKQTVLQKEEERSQPTKTPSSSQEP------PDEGTSGTDVN 1407
+ K+T L+ ++P+ + ++ +EP P+EG +
Sbjct: 529 SVPLAEEEDFDSKEWVIIDKETELKDFPPGAEPSTSGTTDEEPEELRPLPEEGEERRRLG 588
Query: 1408 -------KGSSKNALSSMDPEVRLSSPPGKPEDSSSVDGQSVG----TPVGPETGGEKNG 1456
+G S AL+ D ++ P P S DG+S TP P +G
Sbjct: 589 AEPTVRPRGRSMQALAEED--LQHLPPQPLPPQLSQGDGRSETSQPPTPGSPSHSPLHSG 646
Query: 1457 PEEEEEEDFDDLTQDEEDEMSSASEESVLSVP--------------ELQETMEKLTWLAS 1502
P E D T + S A V +P +L + E+ L
Sbjct: 647 PRPRRRES--DPTGPQRQVFSVAPPFEVNGLPRAVPLSLPYQDFKRDLSDYRERARLLNR 704
Query: 1503 ERRMS----------------------QEGESEEENSQEENSEPEEEEEEEAEGMESLQK 1540
RR+ +E E EEE +EE E EEEEEEE E E ++
Sbjct: 705 VRRVGFSHMLLTTPQVPLAPVQPQANGKEEEEEEEEDEEEEEEDEEEEEEEEEEEEEEEE 764
Query: 1541 EDEMTDEAVGDSA---EKPPTFASPETAPEVETSRTPPGESIKAAGKGRNNHRARNKRGS 1597
E+E +EA A P S E T R+ G + R R
Sbjct: 765 EEEEEEEAAAAVALGEVLGPRSGSSSEGSERSTDRSQEGAPSTLLADDQKESRGRASMAD 824
Query: 1598 RARASKDTSKLLLLYDEDILERDPL 1622
++ SK L+L +++ P+
Sbjct: 825 GDLEPEEGSKTLVLVSPGDMKKSPV 849
Score = 35.0 bits (79), Expect = 0.83
Identities = 20/84 (23%), Positives = 35/84 (41%)
Query: 340 IPTWNISPIKKANEIKPPQFVDIHLEEDDSSDEEYQPDDEEEDETAEESLLESDVESTAS 399
+P + P E + + D EE+D +EE + ++EEE+E EE E+
Sbjct: 720 VPLAPVQPQANGKEEEEEEEEDEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEAAAAVALG 779
Query: 400 SPRGAKKSRLRQSSEMTETDEESG 423
G + + SE + + G
Sbjct: 780 EVLGPRSGSSSEGSERSTDRSQEG 803
Score = 33.5 bits (75), Expect = 2.4
Identities = 23/97 (23%), Positives = 48/97 (49%), Gaps = 7/97 (7%)
Query: 341 PTWNISPIKKANEIKPPQFVDIHLEEDDSSDEEYQPDDEEEDETAEESLLESDVESTASS 400
P ++P++ K + + EE++ DEE + ++EEE+E EE E + + A +
Sbjct: 718 PQVPLAPVQPQANGKEEEEEEEEDEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEAAAAVA 777
Query: 401 ------PR-GAKKSRLRQSSEMTETDEESGILSEAEK 430
PR G+ +S++ ++ S +L++ +K
Sbjct: 778 LGEVLGPRSGSSSEGSERSTDRSQEGAPSTLLADDQK 814
Score = 32.0 bits (71), Expect = 7.0
Identities = 43/186 (23%), Positives = 69/186 (37%), Gaps = 13/186 (6%)
Query: 1788 EEINWTEEKEYEFDGFEEVALPDVEEEEEPPKIPTASKNKRKKEIGVQNHDKETEWPDGA 1847
EE + EE+E E + EE + EEEEE + A+ + +G ++ +G+
Sbjct: 738 EEEDEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEAAAAVALGEVLGPRSGSSS----EGS 793
Query: 1848 KDCACSCHEGGPDSKLKKSKRRSCSHCSSKVCD------SKSYKSKEPHELVGSSPHREA 1901
+ EG P + L ++ S S D SK+ P ++ S E
Sbjct: 794 ERSTDRSQEGAPSTLLADDQKESRGRASMADGDLEPEEGSKTLVLVSPGDMKKSPVTAEL 853
Query: 1902 SPMPGAKEAGQGKDMMEEEAPEERE---STEATQSRTVRTTRKGEMPVSGLAVGSTLPSP 1958
+P P E P + S T S +++ K P +GL G+
Sbjct: 854 APDPDLGTLAALTPQHERPQPTGSQLDVSEPGTLSSVLKSEPKPPGPGAGLGAGTVTTGV 913
Query: 1959 REVTVT 1964
V VT
Sbjct: 914 GGVAVT 919
Score = 31.6 bits (70), Expect = 9.2
Identities = 57/263 (21%), Positives = 101/263 (38%), Gaps = 29/263 (11%)
Query: 1193 PLNQSLVASSVSPLIVSGNSVNLPIPSTPEDKAHVNVDIACAVADGENAFQGLEPKLEPQ 1252
PL L S ++ + G++++ TP + A ++ A+ADG LEP P+
Sbjct: 978 PLENGLALSGLNGAEIEGSALSGAPRETPSEMATNSLPNGPALADGPAPVSPLEP--SPE 1035
Query: 1253 ELSPLSATVFPKVEHSPGPPLADAECQEGLSENSACRWTVVKTEE--GRQALEPLPQGIQ 1310
++ AT+ P+ PG R V+ +EE G + L +
Sbjct: 1036 KV----ATISPRRHAMPG-------------SRPRSRIPVLLSEEDTGSEPSGSLSAKER 1078
Query: 1311 ESLNNPTPGDLEEIVKMEPEEAREEISGSPERDICDDIKVEHAVELDTGAPSEELSSAGE 1370
S DL +V ME + R + + + A E +G SEE + A E
Sbjct: 1079 WSKRARPQQDLARLV-MEKRQGRLLLRLASGASSSSSEEQRRASETLSGTGSEEDTPASE 1137
Query: 1371 VTKQTVLQKEEERSQPTKT----PSSSQEP-PDEGTSGTDVNKGSSKNALSSMDPEVRLS 1425
L ++ R+ T++ P + P P + G++ +++ ++L
Sbjct: 1138 --PAAALPRKSGRAAATRSRIPRPIGLRMPMPVAAQQPASRSHGAAPALDTAITSRLQLQ 1195
Query: 1426 SPPGKPEDSSSVDGQSVGTPVGP 1448
+PPG + Q G +GP
Sbjct: 1196 TPPGSATAADLRPKQPPGRGLGP 1218
>gi|210032580 SET domain containing 1B [Homo sapiens]
Length = 1923
Score = 57.0 bits (136), Expect = 2e-07
Identities = 56/201 (27%), Positives = 87/201 (43%), Gaps = 20/201 (9%)
Query: 1375 TVLQKEEERSQPTKTPSSSQEPPDEGTSGTDVNKGSSKNALSSMDPE-VRLSSPPGKPED 1433
T +++R +P+ +S E +E D + + L+ DP+ V + P +P +
Sbjct: 972 TTSSGDQKRLRPS---TSVDEEDEESERERDRDMADTPCELAKRDPKGVGVRRRPARPLE 1028
Query: 1434 SSSVDGQSVGTPVGPE---TGGEKNGPEEEEEEDFDD--------LTQDEEDEMSSASEE 1482
S + + E T E+ EEEEEED DD D+ED S + E
Sbjct: 1029 LDSGGEEDEKESLSEEQESTEEEEEAEEEEEEEDDDDDDSDDRDESENDDEDTALSEASE 1088
Query: 1483 SVLSVPELQETMEKLTWLASERRMSQEGESEEENSQEENSEPEEEEEEEAEGMESLQKED 1542
+ +ET+ +T A S+ ES E S E+S E+EEE E ++E+
Sbjct: 1089 KDEGDSDEEETVSIVTSKAEATSSSESSESSEFESSSESSPSSSEDEEEVVARE--EEEE 1146
Query: 1543 EMTDEAVGDSAEKPPTFASPE 1563
E +E V AE+ A PE
Sbjct: 1147 EEEEEMV---AEESMASAGPE 1164
Score = 48.9 bits (115), Expect = 6e-05
Identities = 66/257 (25%), Positives = 100/257 (38%), Gaps = 47/257 (18%)
Query: 1354 VELDTGAPSEELSSAGEVTKQTV----LQKEEERSQPTKTPSSSQEPPDEGTSGTDVNKG 1409
+ELD+G +E S E + T ++EEE S ++ + T +++
Sbjct: 1027 LELDSGGEEDEKESLSEEQESTEEEEEAEEEEEEEDDDDDDSDDRDESENDDEDTALSEA 1086
Query: 1410 SSKNALSSMDPEVRLSSPPGKPE--------DSSSVDGQSVGTPVGPETGGEKNGPEEEE 1461
S K+ S D E +S K E +SS + S +P E E EEEE
Sbjct: 1087 SEKDEGDS-DEEETVSIVTSKAEATSSSESSESSEFESSSESSPSSSEDEEEVVAREEEE 1145
Query: 1462 EEDFDDLTQDEEDEMSSASEESVLSV--PELQETMEKLTWLASERRMSQEGESEEENSQE 1519
EE EE+EM +EES+ S + ++ E+ + G EE + +
Sbjct: 1146 EE--------EEEEM--VAEESMASAGPEDFEQDGEEAALAPGAPAVDSLGMEEEVDIET 1195
Query: 1520 ENSEPEEEE------------EEEAEGMESLQKEDEMTDEAVGDSAEKPPTF-------A 1560
E PEE EE A+ E +E ++ E + +PP
Sbjct: 1196 EAVAPEERPSMLDEPPLPVGVEEPADSREP-PEEPGLSQEGAMLLSPEPPAKEVEARPPL 1254
Query: 1561 SPETAPE--VETSRTPP 1575
SPE APE +E PP
Sbjct: 1255 SPERAPEHDLEVEPEPP 1271
Score = 38.5 bits (88), Expect = 0.075
Identities = 34/166 (20%), Positives = 71/166 (42%), Gaps = 13/166 (7%)
Query: 1471 DEEDEMSSASEESVLSVPELQETMEKLTWLASERRMS---------QEGESEEENSQEEN 1521
DEEDE S + ++ + + RR + +E E E + ++E+
Sbjct: 988 DEEDEESERERDRDMADTPCELAKRDPKGVGVRRRPARPLELDSGGEEDEKESLSEEQES 1047
Query: 1522 SEPEEEEEEEAEGMESLQKEDEMTDEAVGDSAEKPPTFASPETAPEVETSRTPPGESIKA 1581
+E EEE EEE E + + + DE+ D + + AS + + + T + KA
Sbjct: 1048 TEEEEEAEEEEEEEDDDDDDSDDRDESENDDEDTALSEASEKDEGDSDEEETVSIVTSKA 1107
Query: 1582 AGKGRNNHRARNKRGSRARASKDTSKLLLLYDEDILERDPLREQKD 1627
+ ++ S + +S +S+ +E+++ R+ E+++
Sbjct: 1108 EATSSSESSESSEFESSSESSPSSSE----DEEEVVAREEEEEEEE 1149
Score = 35.8 bits (81), Expect = 0.49
Identities = 29/115 (25%), Positives = 44/115 (38%), Gaps = 5/115 (4%)
Query: 1003 PLLIQPSPSLQPSFNPGKTPARSTHSEAPPSKMVLRIPHPIQPATVLQTVPGVPPLGVSG 1062
P P+P + +F+P +TP H PP + + + + P PPL +
Sbjct: 384 PAQATPAPGFKSAFSPYQTPV--AHFPPPPEEPTATAAFGARDSGEFRRAPAPPPLPPAE 441
Query: 1063 GESFESPAALPAVPPEARTSFPLSESQTL-LSSAPVPKVMLPSL--APSKFRKPY 1114
+ E P P PP S L T S P P+L +P+ KP+
Sbjct: 442 PLAKEKPGTPPGPPPPDTNSMELGGRPTFGWSPEPCDSPGTPTLESSPAGPEKPH 496
Score = 35.8 bits (81), Expect = 0.49
Identities = 45/204 (22%), Positives = 78/204 (38%), Gaps = 29/204 (14%)
Query: 365 EEDDSSDEEYQPDDEEEDETAEESLLESDVESTASSPRGAKKSRLRQSSEMTETD----E 420
EE +S++EE + ++EEE+E + + D + S + + L ++SE E D E
Sbjct: 1043 EEQESTEEEEEAEEEEEEEDDD----DDDSDDRDESENDDEDTALSEASEKDEGDSDEEE 1098
Query: 421 ESGILSEAEKVTTPAIRHISAEVVPMGPPPPPKPKQTRDSTFMEKLHAVDEELASSPVCM 480
I++ + T+ + S+E P + + E+ +EE + M
Sbjct: 1099 TVSIVTSKAEATSSSESSESSEFESSSESSPSSSEDEEEVVAREEEEEEEEEEMVAEESM 1158
Query: 481 DSFQPMD------DSLIAFRTRSKMPLKDVPLGQLEAELQAPDITPDMYDPNTADDEDWK 534
S P D ++ +A + L +E E AP+ P M D
Sbjct: 1159 ASAGPEDFEQDGEEAALAPGAPAVDSLGMEEEVDIETEAVAPEERPSMLDEPPL------ 1212
Query: 535 MWLGGLMNDDVGNEDEADDDDDPE 558
VG E+ AD + PE
Sbjct: 1213 ---------PVGVEEPADSREPPE 1227
Score = 35.4 bits (80), Expect = 0.63
Identities = 52/243 (21%), Positives = 91/243 (37%), Gaps = 28/243 (11%)
Query: 453 KPKQTRDSTFMEKLHAVDEELASSPVCMDSFQPMDDSLIAFRTRSKMPLKDVPLGQ---- 508
+P + D E D ++A +P + P + R R PL+ G+
Sbjct: 982 RPSTSVDEEDEESERERDRDMADTPCELAKRDPKG---VGVRRRPARPLELDSGGEEDEK 1038
Query: 509 --LEAELQAPDITPDMYDPNTADDEDWKMWLGGLMNDDVGNEDEADDDDDPEYNFLEDLD 566
L E ++ + + + +D+D +DD + DE+++DD E L +
Sbjct: 1039 ESLSEEQESTEEEEEAEEEEEEEDDD---------DDDSDDRDESENDD--EDTALSEAS 1087
Query: 567 EPDTEDFRTDRAVRI-TKKEVNELMEELFETFQDEMGFSNMEDDGPEEEECVAEPRPNFN 625
E D D + V I T K E E+ + E + +EEE VA
Sbjct: 1088 EKDEGDSDEEETVSIVTSKAEATSSSESSESSEFESSSESSPSSSEDEEEVVAREEEEEE 1147
Query: 626 TPQALRFEEPLANLLNEQHRTVKELFEQLKMKKSSAKQLQEVEKVKPQSEKVHQTLILDP 685
+ + EE +A+ E FEQ + + A V+ + + E +T + P
Sbjct: 1148 EEEEMVAEESMASAGPED-------FEQDGEEAALAPGAPAVDSLGMEEEVDIETEAVAP 1200
Query: 686 AQR 688
+R
Sbjct: 1201 EER 1203
Score = 33.1 bits (74), Expect = 3.1
Identities = 25/80 (31%), Positives = 31/80 (38%), Gaps = 17/80 (21%)
Query: 1008 PSPSLQPSFNPGKTPARSTHSEAPPSKMVLRIPHPIQPATVLQTVPGVPPLGVSGGESFE 1067
P P QP F P P PP+ + +P P PA PGVPP
Sbjct: 695 PPPPPQPGF-PMPPPLPPPPPPPPPAHPAVTVPPPPLPAP-----PGVPP---------- 738
Query: 1068 SPAALPAVPPEARTSFPLSE 1087
P LP +PP FP+ +
Sbjct: 739 -PPILPPLPPFPPGLFPVMQ 757
>gi|218505787 protocadherin 15 isoform CD2-1 precursor [Homo sapiens]
Length = 1790
Score = 56.2 bits (134), Expect = 3e-07
Identities = 63/271 (23%), Positives = 102/271 (37%), Gaps = 39/271 (14%)
Query: 1369 GEVTKQTVLQKEEERSQPTKTPSSS---QEPPDEGTSGTDVNKGSSKNALSSMDPEVRLS 1425
GEV + + EEE +P K +EP +E + K + + R+
Sbjct: 1492 GEVVGEAEEEYEEEEEEPKKIKKPKVEIREPSEEEEVVVTIEKPPAAEPTYTTWKRARIF 1551
Query: 1426 SPPGKPEDSSSVDGQSVGTPVGPETGGEKNGPEEEEEEDFDDLTQDEEDEMSSASEESVL 1485
P V G + + G E EEE++D+ LT D+E+ S E
Sbjct: 1552 -----PMIFKKVRGLADKRGIVDLEGEEWQRRLEEEDKDYLKLTLDQEEATESTVESEEE 1606
Query: 1486 SVPELQETMEKLTWLASERRMSQEGESEEENSQEENSEPEEEEEE--EAEGMESL----- 1538
S + E E+ + + +E ESE + +EE+S PE EE E E+EG ++
Sbjct: 1607 SSSDYTEYSEEESEFSESETTEEESESETPSEEEESSTPESEESESTESEGEKARKNIVL 1666
Query: 1539 -----------------------QKEDEMTDEAVGDSAEKPPTFASPETAPEVETSRTPP 1575
QKE +M +E + E P T PE +
Sbjct: 1667 ARRRPMVEEVKEVKGRKEEPQEEQKEPKMEEEEHSEEEESGPAPVEESTDPEAQ-DIPEE 1725
Query: 1576 GESIKAAGKGRNNHRARNKRGSRARASKDTS 1606
G + A+ +G ++ GS + +S+ S
Sbjct: 1726 GSAESASVEGGVESEEESESGSSSSSSESQS 1756
Score = 47.4 bits (111), Expect = 2e-04
Identities = 82/352 (23%), Positives = 127/352 (36%), Gaps = 32/352 (9%)
Query: 1243 QGLEPKLEPQELSPLSATVFPKVEHSPGPPLADAECQEGLSENSACRWTVVKTEEGRQAL 1302
Q P +P +P P P PP A E L ++S ++ + + R+ L
Sbjct: 1428 QAALPAAKPAVPAPAPVAAPPP----PPPPPPGAHLYEELGDSSMHKYEMPQYGSRRRLL 1483
Query: 1303 EPLPQGIQESLNNPTPGDLEEIVKMEPEEAREEISGSPERDICDDIKVEHAVELDTGAPS 1362
P Q + E+V E EE EE P++ +++ E + +
Sbjct: 1484 PPAGQE-----------EYGEVVG-EAEEEYEEEEEEPKKIKKPKVEIREPSEEEEVVVT 1531
Query: 1363 EELSSAGEVTKQTVLQKEEERSQPTKTPSSSQEPPDEGTSGTDVNKGSSKNALSSMDPEV 1422
E A E T T + R P G D+ + L D +
Sbjct: 1532 IEKPPAAEPTYTTW---KRARIFPMIFKKVRGLADKRGI--VDLEGEEWQRRLEEEDKDY 1586
Query: 1423 RLSSPPGKPEDSSSVDGQSVGTPVGPETGGEKNGPEEEE--EEDFDDLTQDEEDEMSSAS 1480
+ + S+V+ + + E E++ E E EE+ + T EE+E S+
Sbjct: 1587 LKLTLDQEEATESTVESEEESSSDYTEYSEEESEFSESETTEEESESETPSEEEESSTPE 1646
Query: 1481 EESVLSVPELQETMEKLTWLASERRMSQ---EGESEEENSQEENSEPEEEEEEEAEGMES 1537
E S E K LA R M + E + +E QEE EP+ EEEE +E ES
Sbjct: 1647 SEESESTESEGEKARKNIVLARRRPMVEEVKEVKGRKEEPQEEQKEPKMEEEEHSEEEES 1706
Query: 1538 -LQKEDEMTDEAVGD-----SAEKPPTFASPETAPEVETSRTPPGESIKAAG 1583
+E TD D SAE E+ E E+ + ++ G
Sbjct: 1707 GPAPVEESTDPEAQDIPEEGSAESASVEGGVESEEESESGSSSSSSESQSGG 1758
Score = 40.4 bits (93), Expect = 0.020
Identities = 49/209 (23%), Positives = 88/209 (42%), Gaps = 27/209 (12%)
Query: 1445 PVGPETGGEKNGPEE---EEEEDFDDLTQDEEDEMSSASEESVLSV-----PELQET--- 1493
P G E GE G E EEEE+ + + E+ SEE + V P + T
Sbjct: 1485 PAGQEEYGEVVGEAEEEYEEEEEEPKKIKKPKVEIREPSEEEEVVVTIEKPPAAEPTYTT 1544
Query: 1494 ----------MEKLTWLASERR-MSQEGESEEENSQEENSEPEEEEEEEAEGMESLQKED 1542
+K+ LA +R + EGE + +EE+ + + ++ E ES + +
Sbjct: 1545 WKRARIFPMIFKKVRGLADKRGIVDLEGEEWQRRLEEEDKDYLKLTLDQEEATESTVESE 1604
Query: 1543 EMTDEAVGDSAEKPPTFASPETAPEVETSRTPPGESIKAAGKGRNNHRARNKRGSRARAS 1602
E + + +E+ F+ ET E S TP E + + + ++ G +AR +
Sbjct: 1605 EESSSDYTEYSEEESEFSESETTEEESESETPSEEEESSTPESEESESTESE-GEKARKN 1663
Query: 1603 KDTSKLLLLYDE--DILER--DPLREQKD 1627
++ + +E ++ R +P EQK+
Sbjct: 1664 IVLARRRPMVEEVKEVKGRKEEPQEEQKE 1692
Score = 38.1 bits (87), Expect = 0.098
Identities = 32/117 (27%), Positives = 51/117 (43%), Gaps = 8/117 (6%)
Query: 364 LEEDDSSDEEYQPDDEEEDETAEESLLESDVESTASSPRGAKKSRLRQSSEMTETDEESG 423
+E ++ S +Y EEE E +E E + ES S + + SE TE++ E
Sbjct: 1601 VESEEESSSDYTEYSEEESEFSESETTEEESESETPSEEEESSTPESEESESTESEGE-- 1658
Query: 424 ILSEAEKVTTPAIRHISAEVVP--MGPPPPPKPKQTRDSTFMEKLHAVDEELASSPV 478
+A K A R E V G P+ +Q ++ E+ H+ +EE +PV
Sbjct: 1659 ---KARKNIVLARRRPMVEEVKEVKGRKEEPQEEQ-KEPKMEEEEHSEEEESGPAPV 1711
Score = 34.7 bits (78), Expect = 1.1
Identities = 26/71 (36%), Positives = 35/71 (49%), Gaps = 4/71 (5%)
Query: 364 LEEDDSSDEEYQPDDEEEDETAEESLLESDVESTASSPRGAKKSRLRQSSEMTETDEESG 423
LEE+D + D EE E+ ES ES + T S ++ S SE TE + ES
Sbjct: 1579 LEEEDKDYLKLTLDQEEATESTVESEEESSSDYTEYSEEESEFS----ESETTEEESESE 1634
Query: 424 ILSEAEKVTTP 434
SE E+ +TP
Sbjct: 1635 TPSEEEESSTP 1645
>gi|153945728 microtubule-associated protein 1B [Homo sapiens]
Length = 2468
Score = 56.2 bits (134), Expect = 3e-07
Identities = 175/907 (19%), Positives = 316/907 (34%), Gaps = 150/907 (16%)
Query: 1328 EPEEAREEISGSPERDICDDIKVEHAVELDTGAPSEELSSAGEVTKQTVLQKEEERSQPT 1387
+P +++++G + K++ + E L A + ++KE + P
Sbjct: 513 QPLATQKDLTGQVPTPVVKQTKLKQRAD-----SRESLKPAAKPLPSKSVRKESKEETPE 567
Query: 1388 KTPSSSQEPPDEGTSGTDVNKGSSKNALSSMDPEVRLSSPPGKPEDS--SSVDGQSVGTP 1445
T + E P + S V K + P V P K E S + + T
Sbjct: 568 VTKVNHVEKPPKVESKEKVMVKKDKPIKTETKPSVTEKEVPSKEEPSPVKAEVAEKQATD 627
Query: 1446 VGPETGGEKNGPEEEEEEDFDDLTQDEEDEMSSASEESVLSVPELQETMEKLTWLASERR 1505
V P+ EK +E + + D + E+ + A +E + + ++ ++ ++
Sbjct: 628 VKPKAAKEKTVKKETKVKPEDKKEEKEKPKKEVAKKEDKTPIKKEEKPKKEEVKKEVKKE 687
Query: 1506 MSQEGESEEENSQEENSEP----EEEEEEEAEGMESLQKEDEMTDEAVGDSAEKPPTFAS 1561
+ +E + E + ++ + P +E ++EE + ++ +KE + + + A+K T S
Sbjct: 688 IKKEEKKEPKKEVKKETPPKEVKKEVKKEEKKEVKKEEKEPKKEIKKLPKDAKKSSTPLS 747
Query: 1562 PETAPEVETSRTP-PGESIK----AAGKGRNNHRAR--NKRGSRARA-----SKDTSKLL 1609
P + P ES+K AAGK + + + K G A A +
Sbjct: 748 EAKKPAALKPKVPKKEESVKKDSVAAGKPKEKGKIKVIKKEGKAAEAVAAAVGTGATTAA 807
Query: 1610 LLYDEDILERDPLREQKDLAFAQAYLTRVREALQHIPGKYEDFLQVIYEFESSTQRRTAV 1669
++ I P +E EA + + ED + E ++ V
Sbjct: 808 VMAAAGIAAIGPAKE--------------LEAERSLMSSPEDLTKDFEELKAE-----EV 848
Query: 1670 DLYKSLQILLQDWPQLLKDFAAFLLPEQALACGLFEEQQAFEKSRKFLRQLEICFAENPS 1729
D+ K ++ L +L++D E+ L E +K R+ + AE+P
Sbjct: 849 DVTKDIKPQL----ELIED-------EEKLKETEPVEAYVIQKEREVTKGP----AESPD 893
Query: 1730 HHQKIIKVLQGCADCLPQEITELKTQMWQLLKGHDHLQDEFSIFFDHLRPAASRMGDFEE 1789
I +G +C Q EL+ Q + + +DE + F + +S GD+EE
Sbjct: 894 EG---ITTTEGEGEC-EQTPEELEPVEKQGVDDIEKFEDEGAGFEE-----SSETGDYEE 944
Query: 1790 INWTEE-KEYEFDGFEEVALP----DVEEEEEPPKIPTASKNKRKKEIGVQNHDKETEWP 1844
TEE +E E DG E V + E+EE K + + K+E D+ E
Sbjct: 945 KAETEEAEEPEEDGEEHVCVSASKHSPTEDEESAKAEADAYIREKRESVASGDDRAEEDM 1004
Query: 1845 DGA---KDCACSCHEGGPDSKLKKSKRRSCSHCSSKVCD--------------------- 1880
D A + S E + K + ++ + D
Sbjct: 1005 DEAIEKGEAEQSEEEADEEDKAEDAREEEYEPEKMEAEDYVMAVVDKAAEAGGAEEQYGF 1064
Query: 1881 ----SKSYKSKEPHELVGSSPHREASPMPGAKEAGQGKDMMEEEAPEERESTEATQSRTV 1936
+K ++ P SS H E P EA + E+ PEE +T T+
Sbjct: 1065 LTTPTKQLGAQSPGREPASSIHDETLPGGSESEATASDEENREDQPEEFTATSGYTQSTI 1124
Query: 1937 RTTRKGEMPVSGLAVGSTLPSPREVTVTERLLLDGPPPHSPETPQFPPTTGAVLYTVKRN 1996
S+ P+P + T R ++ ++ ET P+ V T +
Sbjct: 1125 EI--------------SSEPTPMDEMSTPRDVM-SDETNNEETES--PSQEFVNITKYES 1167
Query: 1997 QVGPEVRSCPKASPRLQKEREGQKAVSESEALMLVWDASETEKLPGTVEPPASFLSPVSS 2056
+ + S P L EG K + D + T+ PP+S S
Sbjct: 1168 SLYSQEYSKPADVTPLNGFSEGSKTDAT--------DGKDYNASASTISPPSSMEEDKFS 1219
Query: 2057 KT--RDAGRRHVSGKPDTQERWLPSSRARVKTRDRTCPVHESPSGIDTSETSPKAPRGGL 2114
++ RDA V T + +S S + + + SP
Sbjct: 1220 RSALRDAYCSEVKA-------------------STTLDIKDSISAVSSEKVSPSKSPSLS 1260
Query: 2115 AKDSGTQAKGPEGEQQPKAAEATVCANNSKVSSTGEKVVLWTREADRVILTMCQEQGAQP 2174
K P GE ++ ++ N KVS+ E + V+ C +
Sbjct: 1261 PSPPSPLEKTPLGE---RSVNFSLTPNEIKVSAEAEVAPVSPEVTQEVVEEHC--ASPED 1315
Query: 2175 QTFNIIS 2181
+T ++S
Sbjct: 1316 KTLEVVS 1322
Score = 43.9 bits (102), Expect = 0.002
Identities = 43/186 (23%), Positives = 75/186 (40%), Gaps = 22/186 (11%)
Query: 1316 PTPGDLEEIVKMEPEEAREEISGSPERDICDDIKVEHAVELDTGAPSEELSSAGEVTKQT 1375
P+ + E K EP + E++ D+ E V+ +T E+ E K+
Sbjct: 600 PSVTEKEVPSKEEPSPVKAEVAEKQATDVKPKAAKEKTVKKETKVKPEDKKEEKEKPKKE 659
Query: 1376 VLQKEEERSQPTKTPSSSQEPPDEGTSGTDVNKGSSKNALSSMDPEVRLSSPPGKPEDSS 1435
V +KE+ KTP +E P + +V K K EV+ +PP
Sbjct: 660 VAKKED------KTPIKKEEKPKKEEVKKEVKKEIKKEEKKEPKKEVKKETPP------- 706
Query: 1436 SVDGQSVGTPVGPETGGEKNGPEEEEEEDFDDLTQDEEDE---MSSASEESVL--SVPEL 1490
+ V V E E E+E +++ L +D + +S A + + L VP+
Sbjct: 707 ----KEVKKEVKKEEKKEVKKEEKEPKKEIKKLPKDAKKSSTPLSEAKKPAALKPKVPKK 762
Query: 1491 QETMEK 1496
+E+++K
Sbjct: 763 EESVKK 768
Score = 38.5 bits (88), Expect = 0.075
Identities = 86/373 (23%), Positives = 131/373 (35%), Gaps = 83/373 (22%)
Query: 1219 STPEDKAHVNVDIACAVADGENAFQGLEPKLEP-------QELSPLSATVFPKV-EHSPG 1270
S+PED + D A+ + + ++P+LE +E P+ A V K E + G
Sbjct: 831 SSPED---LTKDFEELKAEEVDVTKDIKPQLELIEDEEKLKETEPVEAYVIQKEREVTKG 887
Query: 1271 PPLADAECQEGLSENSACRWTVVKTEE-GRQALEPLPQ------GIQESLNNPTPGDLEE 1323
P + E C T + E +Q ++ + + G +ES GD EE
Sbjct: 888 PAESPDEGITTTEGEGECEQTPEELEPVEKQGVDDIEKFEDEGAGFEESSET---GDYEE 944
Query: 1324 IVKMEPEEAREEISGSPERDICDDIKVEHAVELDTGAPSEELSSAGEVTKQTVLQKEEER 1383
K E EEA E PE D + + V +P+E+ SA + E+R
Sbjct: 945 --KAETEEAEE-----PEEDGEEHV----CVSASKHSPTEDEESAKAEADAYI---REKR 990
Query: 1384 SQPTKTPSSSQEPPDEGTSGTDVNKGSSKNALSSMDPEVRLSSPPGKPEDSSSVDGQSVG 1443
++E DE + KG ++ + D E K ED+
Sbjct: 991 ESVASGDDRAEEDMDEA-----IEKGEAEQSEEEADEE-------DKAEDARE------- 1031
Query: 1444 TPVGPETGGEKNGPEEEEEEDFDDLTQDEEDEMSSASEE-SVLSVPE----LQETMEKLT 1498
E+ PE+ E ED+ D+ E A E+ L+ P Q +
Sbjct: 1032 ---------EEYEPEKMEAEDYVMAVVDKAAEAGGAEEQYGFLTTPTKQLGAQSPGREPA 1082
Query: 1499 WLASERRMSQEGESEEENSQEENSEPEEEEEEEAEGM---------------ESLQKEDE 1543
+ + ESE S EEN E + EE G E D
Sbjct: 1083 SSIHDETLPGGSESEATASDEENREDQPEEFTATSGYTQSTIEISSEPTPMDEMSTPRDV 1142
Query: 1544 MTDEAVGDSAEKP 1556
M+DE + E P
Sbjct: 1143 MSDETNNEETESP 1155
Score = 33.5 bits (75), Expect = 2.4
Identities = 65/263 (24%), Positives = 97/263 (36%), Gaps = 52/263 (19%)
Query: 1362 SEELSSAGEVTKQTVLQKEEERSQPTKTPSSSQEPPD--EGT--SGTDVNKGSSKNALS- 1416
SE +S K ++ E+ P+K+PS S PP E T VN + N +
Sbjct: 1229 SEVKASTTLDIKDSISAVSSEKVSPSKSPSLSPSPPSPLEKTPLGERSVNFSLTPNEIKV 1288
Query: 1417 SMDPEVRLSSPP----------GKPED--------SSSVDGQSVGTPVGPETGGEKNG-- 1456
S + EV SP PED S SV G + TP EK+
Sbjct: 1289 SAEAEVAPVSPEVTQEVVEEHCASPEDKTLEVVSPSQSVTGSAGHTPYYQSPTDEKSSHL 1348
Query: 1457 PEEEEEE--------DFDDLTQDEEDEMSSASEESVLSVPELQETMEK-LTWLASERRMS 1507
P E E+ +F D + E S +E VP+ + +EK L+ L S +
Sbjct: 1349 PTEVIEKPPAVPVSFEFSDAKDENERASVSPMDE---PVPDSESPIEKVLSPLRSPPLIG 1405
Query: 1508 QEGESEEENSQEENS------EPEEEEEEEAEGMESLQKEDEMT------DEAVGDSAEK 1555
E E S ++ + P EE+ + + + EMT D+ G S +
Sbjct: 1406 SESAYESFLSADDKASGRGAESPFEEKSGKQGSPDQVSPVSEMTSTSLYQDKQEGKSTDF 1465
Query: 1556 PP---TFASPETAPEVETSRTPP 1575
P F + +VE + P
Sbjct: 1466 APIKEDFGQEKKTDDVEAMSSQP 1488
>gi|55769548 PHD finger protein 14 isoform 2 [Homo sapiens]
Length = 888
Score = 55.5 bits (132), Expect = 6e-07
Identities = 41/158 (25%), Positives = 73/158 (46%), Gaps = 10/158 (6%)
Query: 1430 KPEDSSSVDGQSVGTPVGPETGGEKNGPEEEE---EEDFDDLTQDEEDEMSSASEESVLS 1486
K D+S +G G+ + GE + + EE EE+ ++ + +E+++ +++EE VLS
Sbjct: 32 KVGDASDSEGSGNGSEDASKDSGEGSCSDSEENILEEELNEDIKVKEEQLKNSAEEEVLS 91
Query: 1487 VPELQETMEKLTWLASERRMSQEGESEEENSQEENSEPEEEEEEEAEGMESLQKEDEMTD 1546
+ MEK E + ++E +E+ E E+E+E E E ++ E+
Sbjct: 92 SEKQLIKMEK----KEEEENGERPRKKKEKEKEKEKEKEKEKEREKEKEKATVSENVAAS 147
Query: 1547 EAVGDSAEKPPTFASPETAPEVETSRTPPGESIKAAGK 1584
A A PP + T+P V T+ T E + K
Sbjct: 148 AAATTPATSPP---AVNTSPSVPTTTTATEEQVSEPKK 182
Score = 48.5 bits (114), Expect = 7e-05
Identities = 35/146 (23%), Positives = 66/146 (45%), Gaps = 5/146 (3%)
Query: 1433 DSSSVDGQSVGTPVGPETGGEKNGPEEEEEEDFDDLTQDEEDEM--SSASEESVLSVPEL 1490
DSS VG E G NG E+ ++ + D E+ + +E+ + +L
Sbjct: 24 DSSDDSDFKVGDASDSEGSG--NGSEDASKDSGEGSCSDSEENILEEELNEDIKVKEEQL 81
Query: 1491 QETMEKLTWLASERRMSQEGESEEENSQEENSEPEEEEEEEAEGMESLQKEDEMTDEAVG 1550
+ + E+ + ++ + E + EEEN + + E+E+E+E E + ++E E V
Sbjct: 82 KNSAEEEVLSSEKQLIKMEKKEEEENGERPRKKKEKEKEKEKEKEKEKEREKEKEKATVS 141
Query: 1551 DSAEKPPTFASPETA-PEVETSRTPP 1575
++ +P T+ P V TS + P
Sbjct: 142 ENVAASAAATTPATSPPAVNTSPSVP 167
Score = 42.0 bits (97), Expect = 0.007
Identities = 46/231 (19%), Positives = 92/231 (39%), Gaps = 14/231 (6%)
Query: 1341 ERDICDDIKVEHAVELDTGAPSEELSSAGEVTKQTVLQKEEERSQPTKTPSSSQEPPDEG 1400
E ++ +DIKV+ +L A E LSS ++ K ++EE +P K +E E
Sbjct: 67 EEELNEDIKVKEE-QLKNSAEEEVLSSEKQLIKMEKKEEEENGERPRKKKEKEKEKEKEK 125
Query: 1401 TSGTDVNKGSSKNALSSMDPEVRLSSPP--GKPEDSSSVDGQSVGTPVGPETGGEKNGPE 1458
+ K K +S ++ P P ++S + T + K
Sbjct: 126 EKEKEREKEKEKATVSENVAASAAATTPATSPPAVNTSPSVPTTTTATEEQVSEPKKWNL 185
Query: 1459 EEEEEDFDDLTQDEEDEMSSASEESVLSVPELQETMEKLTWLASERRMSQEGESEEENSQ 1518
D ++ +E ++M E + + T+ K ++ ++ +G++E++ +
Sbjct: 186 RRNRPLLDFVSMEELNDMDDYDSE---DDNDWRPTVVKRKGRSASQKEGSDGDNEDD--E 240
Query: 1519 EENSEPEEEEEEEAEGMESLQKEDEMTDEAVGDSAEKPPTFASPETAPEVE 1569
+E S +E+E +E ED + + G +K S +A + E
Sbjct: 241 DEGSGSDEDENDEG------NDEDHSSPASEGGCKKKKSKVLSRNSADDEE 285
Score = 40.0 bits (92), Expect = 0.026
Identities = 48/235 (20%), Positives = 93/235 (39%), Gaps = 36/235 (15%)
Query: 367 DDSSDEEYQPDDEEEDETAEESLLESD-----VESTASSPRGAKKSRLRQSSEMTETDEE 421
++ +E+ + +E+ +AEE +L S+ +E G + + ++ + E ++E
Sbjct: 67 EEELNEDIKVKEEQLKNSAEEEVLSSEKQLIKMEKKEEEENGERPRKKKEKEKEKEKEKE 126
Query: 422 SGILSEAEKVTTPAIRHISAEVVPMGPPPPPKPKQTRDSTFMEKLHAVDEELASSPVCMD 481
E EK +++A P P T S + EE S P
Sbjct: 127 KEKEREKEKEKATVSENVAASAAATTPATSPPAVNTSPS--VPTTTTATEEQVSEPK--- 181
Query: 482 SFQPMDDSLIAFRTRSKMPLKD-VPLGQLEAELQAPDITPDMYDPNTADDEDWKMWL--- 537
+ R PL D V + +L DM D ++ DD DW+ +
Sbjct: 182 ----------KWNLRRNRPLLDFVSMEELN----------DMDDYDSEDDNDWRPTVVKR 221
Query: 538 -GGLMNDDVGNE-DEADDDDDPEYNFLEDLDEPDTEDFRTDRAVRITKKEVNELM 590
G + G++ D DD+D+ + ++ DE + ED + + KK+ ++++
Sbjct: 222 KGRSASQKEGSDGDNEDDEDEGSGSDEDENDEGNDEDHSSPASEGGCKKKKSKVL 276
Score = 36.2 bits (82), Expect = 0.37
Identities = 20/90 (22%), Positives = 45/90 (50%), Gaps = 6/90 (6%)
Query: 166 EEGGKPQMNSEGEIPSLPSGSQ-SAKPVSQPRKSTQPDVCASPQEKPLRTLFHQPEEEIE 224
++ G M ++ + +LP G++ S + + +P K DV P++ P+R + +
Sbjct: 777 DQAGSSDMEADMAMETLPDGTKRSRRQIKEPVKFVPQDVPPEPKKIPIRNTRTRGRKRS- 835
Query: 225 DGGLFIPMEEQDNEESEKRRKKKKGTKRKR 254
F+P EE+ E + R++++ +K+
Sbjct: 836 ----FVPEEEKHEERVPRERRQRQSVLQKK 861
Score = 33.5 bits (75), Expect = 2.4
Identities = 55/267 (20%), Positives = 101/267 (37%), Gaps = 34/267 (12%)
Query: 1321 LEEIVKMEPEEAREEISGSPERDICDD----IKVEHAVELDTGA-----PSEELSSAGEV 1371
LEE + + + E++ S E ++ IK+E E + G +E E
Sbjct: 66 LEEELNEDIKVKEEQLKNSAEEEVLSSEKQLIKMEKKEEEENGERPRKKKEKEKEKEKEK 125
Query: 1372 TKQTVLQKEEERSQPTKTPSSSQEPPDEGTSGTDVNKGSSKNALSSMDPEVRLSSPP--- 1428
K+ +KE+E++ ++ ++S TS VN S ++ E ++S P
Sbjct: 126 EKEKEREKEKEKATVSENVAASAAATTPATSPPAVNTSPSVPTTTTATEE-QVSEPKKWN 184
Query: 1429 ---GKP-------------EDSSSVDGQSVGTPVGPETG---GEKNGPEEEEEEDFDDLT 1469
+P +D S D V G +K G + + E+D D+ +
Sbjct: 185 LRRNRPLLDFVSMEELNDMDDYDSEDDNDWRPTVVKRKGRSASQKEGSDGDNEDDEDEGS 244
Query: 1470 QDEEDEMSSASEESVLSVPELQETMEKLTWLASERRMSQEGESEEENSQEENSEPEEEEE 1529
+EDE ++E S +K + + S E + + + ++ E+
Sbjct: 245 GSDEDENDEGNDEDHSSPASEGGCKKKKSKVLSRNSADDEELTNDSLTLSQSKSNEDSLI 304
Query: 1530 EEAEGMESLQKEDEMTDEAV--GDSAE 1554
E S QK D + V GD++E
Sbjct: 305 LEKSQNWSSQKMDHILICCVCLGDNSE 331
>gi|55769550 PHD finger protein 14 isoform 1 [Homo sapiens]
Length = 948
Score = 55.5 bits (132), Expect = 6e-07
Identities = 41/158 (25%), Positives = 73/158 (46%), Gaps = 10/158 (6%)
Query: 1430 KPEDSSSVDGQSVGTPVGPETGGEKNGPEEEE---EEDFDDLTQDEEDEMSSASEESVLS 1486
K D+S +G G+ + GE + + EE EE+ ++ + +E+++ +++EE VLS
Sbjct: 32 KVGDASDSEGSGNGSEDASKDSGEGSCSDSEENILEEELNEDIKVKEEQLKNSAEEEVLS 91
Query: 1487 VPELQETMEKLTWLASERRMSQEGESEEENSQEENSEPEEEEEEEAEGMESLQKEDEMTD 1546
+ MEK E + ++E +E+ E E+E+E E E ++ E+
Sbjct: 92 SEKQLIKMEK----KEEEENGERPRKKKEKEKEKEKEKEKEKEREKEKEKATVSENVAAS 147
Query: 1547 EAVGDSAEKPPTFASPETAPEVETSRTPPGESIKAAGK 1584
A A PP + T+P V T+ T E + K
Sbjct: 148 AAATTPATSPP---AVNTSPSVPTTTTATEEQVSEPKK 182
Score = 48.5 bits (114), Expect = 7e-05
Identities = 35/146 (23%), Positives = 66/146 (45%), Gaps = 5/146 (3%)
Query: 1433 DSSSVDGQSVGTPVGPETGGEKNGPEEEEEEDFDDLTQDEEDEM--SSASEESVLSVPEL 1490
DSS VG E G NG E+ ++ + D E+ + +E+ + +L
Sbjct: 24 DSSDDSDFKVGDASDSEGSG--NGSEDASKDSGEGSCSDSEENILEEELNEDIKVKEEQL 81
Query: 1491 QETMEKLTWLASERRMSQEGESEEENSQEENSEPEEEEEEEAEGMESLQKEDEMTDEAVG 1550
+ + E+ + ++ + E + EEEN + + E+E+E+E E + ++E E V
Sbjct: 82 KNSAEEEVLSSEKQLIKMEKKEEEENGERPRKKKEKEKEKEKEKEKEKEREKEKEKATVS 141
Query: 1551 DSAEKPPTFASPETA-PEVETSRTPP 1575
++ +P T+ P V TS + P
Sbjct: 142 ENVAASAAATTPATSPPAVNTSPSVP 167
Score = 42.0 bits (97), Expect = 0.007
Identities = 46/231 (19%), Positives = 92/231 (39%), Gaps = 14/231 (6%)
Query: 1341 ERDICDDIKVEHAVELDTGAPSEELSSAGEVTKQTVLQKEEERSQPTKTPSSSQEPPDEG 1400
E ++ +DIKV+ +L A E LSS ++ K ++EE +P K +E E
Sbjct: 67 EEELNEDIKVKEE-QLKNSAEEEVLSSEKQLIKMEKKEEEENGERPRKKKEKEKEKEKEK 125
Query: 1401 TSGTDVNKGSSKNALSSMDPEVRLSSPP--GKPEDSSSVDGQSVGTPVGPETGGEKNGPE 1458
+ K K +S ++ P P ++S + T + K
Sbjct: 126 EKEKEREKEKEKATVSENVAASAAATTPATSPPAVNTSPSVPTTTTATEEQVSEPKKWNL 185
Query: 1459 EEEEEDFDDLTQDEEDEMSSASEESVLSVPELQETMEKLTWLASERRMSQEGESEEENSQ 1518
D ++ +E ++M E + + T+ K ++ ++ +G++E++ +
Sbjct: 186 RRNRPLLDFVSMEELNDMDDYDSE---DDNDWRPTVVKRKGRSASQKEGSDGDNEDD--E 240
Query: 1519 EENSEPEEEEEEEAEGMESLQKEDEMTDEAVGDSAEKPPTFASPETAPEVE 1569
+E S +E+E +E ED + + G +K S +A + E
Sbjct: 241 DEGSGSDEDENDEG------NDEDHSSPASEGGCKKKKSKVLSRNSADDEE 285
Score = 40.0 bits (92), Expect = 0.026
Identities = 48/235 (20%), Positives = 93/235 (39%), Gaps = 36/235 (15%)
Query: 367 DDSSDEEYQPDDEEEDETAEESLLESD-----VESTASSPRGAKKSRLRQSSEMTETDEE 421
++ +E+ + +E+ +AEE +L S+ +E G + + ++ + E ++E
Sbjct: 67 EEELNEDIKVKEEQLKNSAEEEVLSSEKQLIKMEKKEEEENGERPRKKKEKEKEKEKEKE 126
Query: 422 SGILSEAEKVTTPAIRHISAEVVPMGPPPPPKPKQTRDSTFMEKLHAVDEELASSPVCMD 481
E EK +++A P P T S + EE S P
Sbjct: 127 KEKEREKEKEKATVSENVAASAAATTPATSPPAVNTSPS--VPTTTTATEEQVSEPK--- 181
Query: 482 SFQPMDDSLIAFRTRSKMPLKD-VPLGQLEAELQAPDITPDMYDPNTADDEDWKMWL--- 537
+ R PL D V + +L DM D ++ DD DW+ +
Sbjct: 182 ----------KWNLRRNRPLLDFVSMEELN----------DMDDYDSEDDNDWRPTVVKR 221
Query: 538 -GGLMNDDVGNE-DEADDDDDPEYNFLEDLDEPDTEDFRTDRAVRITKKEVNELM 590
G + G++ D DD+D+ + ++ DE + ED + + KK+ ++++
Sbjct: 222 KGRSASQKEGSDGDNEDDEDEGSGSDEDENDEGNDEDHSSPASEGGCKKKKSKVL 276
Score = 36.2 bits (82), Expect = 0.37
Identities = 20/90 (22%), Positives = 45/90 (50%), Gaps = 6/90 (6%)
Query: 166 EEGGKPQMNSEGEIPSLPSGSQ-SAKPVSQPRKSTQPDVCASPQEKPLRTLFHQPEEEIE 224
++ G M ++ + +LP G++ S + + +P K DV P++ P+R + +
Sbjct: 777 DQAGSSDMEADMAMETLPDGTKRSRRQIKEPVKFVPQDVPPEPKKIPIRNTRTRGRKRS- 835
Query: 225 DGGLFIPMEEQDNEESEKRRKKKKGTKRKR 254
F+P EE+ E + R++++ +K+
Sbjct: 836 ----FVPEEEKHEERVPRERRQRQSVLQKK 861
Score = 33.5 bits (75), Expect = 2.4
Identities = 55/267 (20%), Positives = 101/267 (37%), Gaps = 34/267 (12%)
Query: 1321 LEEIVKMEPEEAREEISGSPERDICDD----IKVEHAVELDTGA-----PSEELSSAGEV 1371
LEE + + + E++ S E ++ IK+E E + G +E E
Sbjct: 66 LEEELNEDIKVKEEQLKNSAEEEVLSSEKQLIKMEKKEEEENGERPRKKKEKEKEKEKEK 125
Query: 1372 TKQTVLQKEEERSQPTKTPSSSQEPPDEGTSGTDVNKGSSKNALSSMDPEVRLSSPP--- 1428
K+ +KE+E++ ++ ++S TS VN S ++ E ++S P
Sbjct: 126 EKEKEREKEKEKATVSENVAASAAATTPATSPPAVNTSPSVPTTTTATEE-QVSEPKKWN 184
Query: 1429 ---GKP-------------EDSSSVDGQSVGTPVGPETG---GEKNGPEEEEEEDFDDLT 1469
+P +D S D V G +K G + + E+D D+ +
Sbjct: 185 LRRNRPLLDFVSMEELNDMDDYDSEDDNDWRPTVVKRKGRSASQKEGSDGDNEDDEDEGS 244
Query: 1470 QDEEDEMSSASEESVLSVPELQETMEKLTWLASERRMSQEGESEEENSQEENSEPEEEEE 1529
+EDE ++E S +K + + S E + + + ++ E+
Sbjct: 245 GSDEDENDEGNDEDHSSPASEGGCKKKKSKVLSRNSADDEELTNDSLTLSQSKSNEDSLI 304
Query: 1530 EEAEGMESLQKEDEMTDEAV--GDSAE 1554
E S QK D + V GD++E
Sbjct: 305 LEKSQNWSSQKMDHILICCVCLGDNSE 331
>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapiens]
Length = 1124
Score = 55.1 bits (131), Expect = 8e-07
Identities = 60/224 (26%), Positives = 91/224 (40%), Gaps = 15/224 (6%)
Query: 981 LKPVATRFPRKAWRQKRSSVLKPLLIQPSPSLQPSFNPGKTPARSTHSEAPPSKMVLRIP 1040
L P+AT P+ + P PSP +Q F+P +P S S PPS+ +
Sbjct: 642 LSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSP-SATPPSQAPPSLA 700
Query: 1041 HPIQPATVLQTVPGVPPLGVSGGESFESPAALPA----VPPEARTSFPLSESQTLLSSAP 1096
P P V + P PP+ S ++P L A VPP S P+S S T P
Sbjct: 701 AP--PLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQVPPSPPASPPMSPSATPPPRVP 758
Query: 1097 ----VPKVMLPSLAPSKFRKPYVRRRPSKRRGVKASPCMK--PAPVIHHPASVIFTVPAT 1150
P + +P P+ + + P + A+P ++ P+P P F+ P+
Sbjct: 759 PLLAAPPLQVPPSPPASLPMSPLAKPPPQAPPALATPPLQALPSPPASFPGQAPFS-PSA 817
Query: 1151 TVKIVSLGGGCNMIQPVNAA-VAQSPQTIPITTLLVNPTSFPCP 1193
++ + L PV AA + Q P + P + L P P P
Sbjct: 818 SLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTP 861
Score = 42.0 bits (97), Expect = 0.007
Identities = 85/357 (23%), Positives = 126/357 (35%), Gaps = 62/357 (17%)
Query: 963 LGSESRYPLLLPKGVVLKLKPVA----TRFPRKAWRQKRSSVLKPL-LIQPSPSLQPSFN 1017
LG S PL P K +PV P A + PL L PSPS PS
Sbjct: 296 LGPLSSSPLATPSPSGTKARPVPPPDNAATPLPATLPPSPPLATPLPLAPPSPSAPPSLQ 355
Query: 1018 PGKTPARSTHSEAPPSKMVLRIPHPIQPATVLQTVPGV---------------PPLGVSG 1062
+P + S+APPS P+Q LQT+P + PL +S
Sbjct: 356 TLPSPPATPPSQAPPSMTT----PPMQAPPSLQTIPPIQVPHSLTSPSLQAPPSPLALS- 410
Query: 1063 GESFESPAALPAVPPEARTSF---PLSESQTLLSSAPVPKVMLPSLAPSKFRKPYVRRRP 1119
S ++ +L + +A SF ++Q L+S P P P + P
Sbjct: 411 --SLQATTSLGSPTLQATHSFLTMSPRQTQASLTSPSRPASTPPDSPPLQAPLSLPASPP 468
Query: 1120 SKRRGVKASPCMKP--APVIHHPASVIFTV-------PATTVKIVSLGGGCNMIQPVNAA 1170
+ SP + P +P+ HP + ++ P +++ + L ++ P
Sbjct: 469 LQ---TSLSPAVSPLSSPLTIHPLQALSSLASHSPQAPLSSLIMPPLETQSSLAPPSLQT 525
Query: 1171 VAQSPQTIPITTLLVNPTSFPCPLN-----------QSLVASSVSPLIVSGNSVNLPIPS 1219
S T P+ L P+ P PL ++ + PL + + P P
Sbjct: 526 PPASLTTPPLENL---PSLAPPPLQTASAPLTTPHLETPPCPAPCPLQAPPSPLTTPPPE 582
Query: 1220 TPEDKAHVNVDIACAVADGENAFQGL-EPKLEPQELSPLSA---TVFPKVEHSPGPP 1272
TP A A+A QGL P L P P A P ++ P PP
Sbjct: 583 TPSSIATPPPQAPPALA--SPPLQGLPSPPLSPLATPPPQAPPXLALPPLQAPPSPP 637
Score = 40.8 bits (94), Expect = 0.015
Identities = 56/247 (22%), Positives = 88/247 (35%), Gaps = 37/247 (14%)
Query: 995 QKRSSVLKPLLIQPSPSLQ------------PSFNPGKTPARSTHSEAPPSKMVLRIPHP 1042
+ +SS+ P L P SL P P + H E PP P P
Sbjct: 513 ETQSSLAPPSLQTPPASLTTPPLENLPSLAPPPLQTASAPLTTPHLETPPCPA----PCP 568
Query: 1043 IQPATVLQTVPGVPPLGVSGGESFESPAALPAVPPEARTSFPLSESQTLLSSAPVPKVML 1102
+Q T P PP E+P+++ PP+A + Q L S P
Sbjct: 569 LQAPPSPLTTP--PP---------ETPSSIATPPPQAPPALASPPLQGLPSPPLSPLATP 617
Query: 1103 PSLAPSKFRKPYVRRRPSKRRGVKASPCMKPAP------VIHHPASVIFTVPATTVKIVS 1156
P AP P ++ PS SP P+P +H + P+ V+
Sbjct: 618 PPQAPPXLALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPF 677
Query: 1157 LGGGCNMIQPVNAAVAQSPQTIPITTLLV--NPTSFPCPLNQSLVASSVSPLIVSGNSVN 1214
+ P +Q+P ++ L V +P + P P++ S +P ++ +
Sbjct: 678 SPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASP-PMSPSATPPPQAPPPLAAPPLQ 736
Query: 1215 LPIPSTP 1221
+P PS P
Sbjct: 737 VP-PSPP 742
>gi|84043963 eukaryotic translation initiation factor 5B [Homo
sapiens]
Length = 1220
Score = 55.1 bits (131), Expect = 8e-07
Identities = 33/102 (32%), Positives = 56/102 (54%), Gaps = 9/102 (8%)
Query: 1458 EEEEEEDFDDLTQDEEDEMSSASEESVLSVPELQETMEKLTWLASERRMSQEGESEEENS 1517
E EEEED +D D+ + M+S E + ++ + + +E E EEE
Sbjct: 491 EPEEEEDTEDAGLDDWEAMASDEETEKVEGNKVH--------IEVKENPEEEEEEEEEEE 542
Query: 1518 QEENSEPEEEEEEEAEGMESLQKEDEMTDEA-VGDSAEKPPT 1558
++E SE EEEEE E+EG E +++++++DE G + +K P+
Sbjct: 543 EDEESEEEEEEEGESEGSEGDEEDEKVSDEKDSGKTLDKKPS 584
Score = 49.7 bits (117), Expect = 3e-05
Identities = 50/185 (27%), Positives = 80/185 (43%), Gaps = 27/185 (14%)
Query: 1349 KVEHAVELDTGAPSEELSSAGEVTKQTVLQKEEERSQPTKTPSSSQEPPDEGTSGTDVNK 1408
K+ +E + S EL +A EV +Q V +KEE T P +E D +G D
Sbjct: 453 KIPQQLESKEVSESMELCAAVEVMEQGVPEKEE-----TPPPVEPEEEEDTEDAGLD--- 504
Query: 1409 GSSKNALSSMDPEVRLSSPPGKPEDSSSVDGQSVGTPVGPETGGEKNGPEEEEEEDFDDL 1468
D E S E++ V+G V V E EEEEEE+ +D
Sbjct: 505 ----------DWEAMASD-----EETEKVEGNKVHIEVKENPEEE----EEEEEEEEEDE 545
Query: 1469 TQDEEDEMSSASEESVLSVPELQETMEKLTWLASERRMSQEGESEEENSQEENSEPEEEE 1528
+EE+E SE S + + + EK + +++ S+E S+ E +++ EE
Sbjct: 546 ESEEEEEEEGESEGSEGDEEDEKVSDEKDSGKTLDKKPSKEMSSDSEYDSDDDRTKEERA 605
Query: 1529 EEEAE 1533
++A+
Sbjct: 606 YDKAK 610
Score = 43.1 bits (100), Expect = 0.003
Identities = 58/289 (20%), Positives = 117/289 (40%), Gaps = 26/289 (8%)
Query: 153 KEPFSGEPSEEVKEEGGKPQMNSEGEIPSLPSGSQSAKPVSQPRKSTQPDVCASPQEKPL 212
K+ GE E+ KE+ P S+ + ++ K + +K + + +E
Sbjct: 318 KKKKKGEKEEKEKEKKKGP---SKATVKAMQEALAKLKEEEERQKREEEERIKRLEELEA 374
Query: 213 RTLFHQPEEEIEDGGLFIPMEEQDNEESEKRRKKKKG---TKRKRDGRGQ-EGTL----- 263
+ + EE +E ++ E+ K R KK+G TK +R+ R + E TL
Sbjct: 375 K---RKEEERLEQEKR---ERKKQKEKERKERLKKEGKLLTKSQREARARAEATLKLLQA 428
Query: 264 -AYDLKLDDMLD--RTLEDGAKQHNLTAVNVRNILHEVITNEHVVAMMKAAISETEDMPM 320
++ D L R + + K+ + + E + V +M+ + E E+ P
Sbjct: 429 QGVEVPSKDSLPKKRPIYEDKKRKKIPQQLESKEVSESMELCAAVEVMEQGVPEKEETP- 487
Query: 321 FEPKMTRSKLKEVVEKGVVIPTWNISPIKKANEIKPPQFVDIHLEEDDSSDEEYQPDDEE 380
P + + ++ + G + W + E V I ++E+ +EE + ++EE
Sbjct: 488 --PPVEPEEEEDTEDAG--LDDWEAMASDEETEKVEGNKVHIEVKENPEEEEEEEEEEEE 543
Query: 381 EDETAEESLLESDVESTASSPRGAKKSRLRQSSEMTETDEESGILSEAE 429
++E+ EE E + E + K S + S + + + S++E
Sbjct: 544 DEESEEEEEEEGESEGSEGDEEDEKVSDEKDSGKTLDKKPSKEMSSDSE 592
Score = 41.2 bits (95), Expect = 0.012
Identities = 64/290 (22%), Positives = 112/290 (38%), Gaps = 47/290 (16%)
Query: 1322 EEIVKMEPEEAREEISGSPERDICDDIKVEHAVELDTGAPSEELSSAGEVTKQTVLQKEE 1381
E + K++ EE R++ ++ +++ EL+ EE + ++ QKE+
Sbjct: 346 EALAKLKEEEERQKRE--------EEERIKRLEELEAKRKEEERLE--QEKRERKKQKEK 395
Query: 1382 ERSQPTKTPSSSQEPPDEGTSGTDVNKGSSKNALSSMDPEVRLSSPPGKPEDSSSVDGQS 1441
ER + K EG T S + A + + ++L G + S D
Sbjct: 396 ERKERLKK---------EGKLLTK----SQREARARAEATLKLLQAQGV--EVPSKDSLP 440
Query: 1442 VGTPVGPETGGEKNGPEEEEEEDFDDLTQDEEDEMSSASEESVLSVPELQETMEKL---- 1497
P+ E K P++ E ++ E E+ +A E VPE +ET +
Sbjct: 441 KKRPIY-EDKKRKKIPQQLESKEVS-----ESMELCAAVEVMEQGVPEKEETPPPVEPEE 494
Query: 1498 ------TWLASERRMSQEGESEEENSQE------ENSEPEEEEEEEAEGMESLQKEDEMT 1545
L M+ + E+E+ + EN E EEEEEEE E E ++E+E
Sbjct: 495 EEDTEDAGLDDWEAMASDEETEKVEGNKVHIEVKENPEEEEEEEEEEEEDEESEEEEEEE 554
Query: 1546 DEAVGDSAEKPPTFASPETAPEVETSRTPPGESIKAAGKGRNNHRARNKR 1595
E+ G ++ S E + P E + ++ R + +R
Sbjct: 555 GESEGSEGDEEDEKVSDEKDSGKTLDKKPSKEMSSDSEYDSDDDRTKEER 604
Score = 37.4 bits (85), Expect = 0.17
Identities = 66/305 (21%), Positives = 118/305 (38%), Gaps = 78/305 (25%)
Query: 1378 QKEEERSQPTKTPS---SSQEPPDEGTSGTDVNKGSSKNALSSMDPEVRLSSPPGKPEDS 1434
+++E+ S+ K S SS E DE KG KN + P + G +D
Sbjct: 165 EEDEDNSKKIKERSRINSSGESGDESDEFLQSRKGQKKNQKNKPGPNIE----SGNEDDD 220
Query: 1435 SSVDGQSVGTPVGPETGGEKNGPEEE--------EEEDFDDLTQDEEDEMSSA---SEES 1483
+S ++V + E+ +EE E+E+ + +D+ + S EE+
Sbjct: 221 ASFKIKTVAQKKAEKKERERKKRDEEKAKLRKLKEKEELETGKKDQSKQKESQRKFEEET 280
Query: 1484 VLS--------VPELQETMEKLTWLASER--------RMSQEGESEEENSQE-------- 1519
V S +P +E E T + + ++GE EE+ ++
Sbjct: 281 VKSKVTVDTGVIPASEEKAETPTAAEDDNEGDKKKKDKKKKKGEKEEKEKEKKKGPSKAT 340
Query: 1520 ------------ENSEPEEEEEEEA----EGMESLQKEDEMTDEAVGDSAEKPPTFASPE 1563
E E ++ EEEE E +E+ +KE+E ++ E
Sbjct: 341 VKAMQEALAKLKEEEERQKREEEERIKRLEELEAKRKEEERLEQ------------EKRE 388
Query: 1564 TAPEVETSRTPPGESIKAAGKGRNNHRARNKRGSRARASKDTSKLLLLYDEDILERDPLR 1623
+ E R E +K GK +++R +RARA + T KLL ++ +D L
Sbjct: 389 RKKQKEKERK---ERLKKEGK----LLTKSQREARARA-EATLKLLQAQGVEVPSKDSLP 440
Query: 1624 EQKDL 1628
+++ +
Sbjct: 441 KKRPI 445
Score = 34.3 bits (77), Expect = 1.4
Identities = 92/429 (21%), Positives = 170/429 (39%), Gaps = 62/429 (14%)
Query: 161 SEEVKEEGGKPQMNSEGEIPSLPSGSQSAKPVSQPRKSTQPDVCASPQEKPLRTLFHQPE 220
S+++KE + ++NS GE SG +S + + Q RK Q+K + ++P
Sbjct: 171 SKKIKE---RSRINSSGE-----SGDESDEFL-QSRKG---------QKKNQK---NKPG 209
Query: 221 EEIEDGGLFIPMEEQDNEESEK----RRKKKKGTKRKRDGRGQEGTLAYDLKLDDMLDRT 276
IE G +D++ S K +KK + +R+R R +E LK + L+
Sbjct: 210 PNIESGN-------EDDDASFKIKTVAQKKAEKKERERKKRDEEKAKLRKLKEKEELETG 262
Query: 277 LEDGAKQHNLTAVNVRNILHEVITNEHVV--AMMKAAISETEDMPMFE-----PKMTRSK 329
+D +KQ + R E + ++ V ++ A+ + E E K + K
Sbjct: 263 KKDQSKQKE----SQRKFEEETVKSKVTVDTGVIPASEEKAETPTAAEDDNEGDKKKKDK 318
Query: 330 LKEVVEKGVVIPTWNISPIKKANEIKPPQFVDIHLEEDDSSDEEYQPD---DEEEDETAE 386
K+ EK P K + + EE+ EE + +E E + E
Sbjct: 319 KKKKGEKEEKEKEKKKGPSKATVKAMQEALAKLKEEEERQKREEEERIKRLEELEAKRKE 378
Query: 387 ESLLESDVESTASSPRGAKKSRLRQSSE-MTETDEESGILSEAEKVTTPAIRHISAEVVP 445
E LE + +K RL++ + +T++ E+ +EA T + VP
Sbjct: 379 EERLEQEKRERKKQKEKERKERLKKEGKLLTKSQREARARAEA----TLKLLQAQGVEVP 434
Query: 446 MGPPPPPKPKQTRDSTFMEKLHAVDEELASSPVCMDSFQPMDDSLIAFRTRSKMPLKD-- 503
P K D +K + ++L S V + M+ +P K+
Sbjct: 435 SKDSLPKKRPIYED----KKRKKIPQQLESKEVS----ESMELCAAVEVMEQGVPEKEET 486
Query: 504 VPLGQLEAELQAPDITPDMYDPNTADDEDWKMWLGGLMNDDVGNEDEADDDDDPEYNFLE 563
P + E E D D ++ +D+E K+ G ++ +V E +++++ E E
Sbjct: 487 PPPVEPEEEEDTEDAGLDDWEAMASDEETEKV-EGNKVHIEVKENPEEEEEEEEEEEEDE 545
Query: 564 DLDEPDTED 572
+ +E + E+
Sbjct: 546 ESEEEEEEE 554
Score = 34.3 bits (77), Expect = 1.4
Identities = 30/123 (24%), Positives = 54/123 (43%), Gaps = 6/123 (4%)
Query: 1301 ALEPLPQGIQESLNNPTPGDLEEIVKMEPEEAR----EEISGSPERDICDDIKVEHAVEL 1356
A+E + QG+ E P P + EE + + E+A E ++ E + + KV V+
Sbjct: 472 AVEVMEQGVPEKEETPPPVEPEE--EEDTEDAGLDDWEAMASDEETEKVEGNKVHIEVKE 529
Query: 1357 DTGAPSEELSSAGEVTKQTVLQKEEERSQPTKTPSSSQEPPDEGTSGTDVNKGSSKNALS 1416
+ EE E + ++EE S+ ++ ++ DE SG ++K SK S
Sbjct: 530 NPEEEEEEEEEEEEDEESEEEEEEEGESEGSEGDEEDEKVSDEKDSGKTLDKKPSKEMSS 589
Query: 1417 SMD 1419
+
Sbjct: 590 DSE 592
>gi|157738619 smoothelin-like 1 [Homo sapiens]
Length = 512
Score = 55.1 bits (131), Expect = 8e-07
Identities = 88/399 (22%), Positives = 147/399 (36%), Gaps = 64/399 (16%)
Query: 1234 AVADGENAFQGLEPKLEPQE--LSPLSATVFPKVEHSP----GPPLADAECQEGLSENSA 1287
AV + + + + E K+E +E LS TV P ++ G P + + G + N
Sbjct: 5 AVGESDCSAEARE-KMEQKEGKLSEDGTTVSPAADNPEMSGGGAPAEETKGTAGKAINEG 63
Query: 1288 CRWTVVKTEEGRQALEPLPQGIQESLNNPTPGDLEEIVKMEPEEAREEISGSPERDICDD 1347
TE G+Q P G+ L G L+E+ E++ E G + + +
Sbjct: 64 -----PPTESGKQEKAPAEDGMSAELQGEANG-LDEV----KVESQREAGGKEDAEA--E 111
Query: 1348 IKVEHAVELDTGAPSEELSSAGEVTKQTVLQKEEERSQPTKTPSSSQEPPDEGTSGTDVN 1407
+K E + +T S+E++ E TK + EE+ S ++E + SG +
Sbjct: 112 LKKEDGEKEETTVGSQEMTGRKEETKSEPKEAEEKESTLASEKQKAEEKEAKPESGQKAD 171
Query: 1408 KGSSKNALSSMDPEVRLSSPPGKPEDSSSVDGQSVGTPVGPETGGEKNGPEEEEEEDFDD 1467
++ KPE ++V+ + T ETG K E +E+ D+
Sbjct: 172 -----------------ANDRDKPEPKATVEEEDAKTASQEETGQRKECSTEPKEKATDE 214
Query: 1468 LTQDE------EDEMSS------ASEESVLSVPELQETMEKLTWLASERRMSQEGESEEE 1515
+ E EDE + EE+ E + E+ A + ++ G EE
Sbjct: 215 EAKAESQKAVVEDEAKAEPKEPDGKEEAKHGAKEEADAKEE----AEDAEEAEPGSPSEE 270
Query: 1516 NSQEENSEPE-----------EEEEEEAEGMESLQKEDEMTDEAVGDSAEKPPTFASPET 1564
Q+ EPE E E +L + D + +SP
Sbjct: 271 QEQDVEKEPEGGAGVIPSSPEEWPESPTGEGHNLSTDGLGPDCVASGQTSPSASESSPSD 330
Query: 1565 APEVETSRTPPGESIKAAGKGRNNHRARNKRGSRARASK 1603
P+ GE + A + R + AR RG RA+ K
Sbjct: 331 VPQSPPESPSSGEKKEKAPERRVSAPAR-PRGPRAQNRK 368
Score = 35.4 bits (80), Expect = 0.63
Identities = 40/203 (19%), Positives = 69/203 (33%), Gaps = 22/203 (10%)
Query: 1809 PDVEEEEEPPKIPTASKNKRKKEIGVQNHDKETEWPDGAKDCACSCHEGGPDSKLKKSKR 1868
P EEE K + + ++KE + +K T+ A+ + + +
Sbjct: 180 PKATVEEEDAKTASQEETGQRKECSTEPKEKATDEEAKAESQKAVVEDEAKAEPKEPDGK 239
Query: 1869 RSCSHCSSKVCDSKSYKSKEPHELVGSSPHREASPMPGAKEAGQGKDMMEEEAPEEREST 1928
H + + D+K GS + + E G G + +PEE +
Sbjct: 240 EEAKHGAKEEADAKEEAEDAEEAEPGSPSEEQEQDVEKEPEGGAG---VIPSSPEEWPES 296
Query: 1929 EATQSRTVRTTRKGEMPVSGLAVGSTLPSPREVTVTERLLLDGPPPHSPETPQFPPTTGA 1988
+ + T G +A G T PS E P P++P P++G
Sbjct: 297 PTGEGHNLSTDGLGP---DCVASGQTSPSASE----------SSPSDVPQSPPESPSSG- 342
Query: 1989 VLYTVKRNQVGPEVRSCPKASPR 2011
++ + PE R A PR
Sbjct: 343 -----EKKEKAPERRVSAPARPR 360
>gi|132626688 mediator of DNA-damage checkpoint 1 [Homo sapiens]
Length = 2089
Score = 54.7 bits (130), Expect = 1e-06
Identities = 100/445 (22%), Positives = 158/445 (35%), Gaps = 81/445 (18%)
Query: 994 RQKRSSVLKPLLIQPS-PSLQPSFNPGKTPARSTHSEAP-----------PSKMVLRIPH 1041
R RSSV P + P+ P LQPS + + S+A P +V P
Sbjct: 1436 RTNRSSVKTPETVVPTAPELQPSTSTDQPVTPEPTSQATRGRTDRSSVKTPETVVPTAPE 1495
Query: 1042 PIQPATVLQTVPGVPPLGVSGGESFESPA--------ALPAVPPEARTSFPLS------- 1086
A+ Q V P + G S A P + P T P++
Sbjct: 1496 LQASASTDQPVTSEPTSRTTRGRKNRSSVKTPETVVPAAPELQPSTSTDQPVTPEPTSRA 1555
Query: 1087 -ESQTLLSSAPVPKVMLP---SLAPSKFRKPYVRRRPSKRRG---VKASPCMKPAPVIH- 1138
+T SS P+ ++P L PS R V P+ R S P PV+
Sbjct: 1556 TRGRTNRSSVKTPESIVPIAPELQPSTSRNQLVTPEPTSRATRCRTNRSSVKTPEPVVPT 1615
Query: 1139 --HPASVIFTVPATTVKIVSLGGGCNMIQPVNAAVAQSPQTIPITTLLVNPTSFPCPLNQ 1196
P T T K+ S + N + ++P+ + + P + P +Q
Sbjct: 1616 APEPHPTTSTDQPVTPKLTSRATR----RKTNRSSVKTPKPVEPAASDLEPFT---PTDQ 1668
Query: 1197 SLVASSV-----SPLIVSGNSVNLPIPSTPEDKAHVNVDIACAVADGENAFQGLEPKLEP 1251
S+ ++ S + S +P+P+TPE ++ V D + P
Sbjct: 1669 SVTPEAIAQGGQSKTLRSSTVRAMPVPTTPEFQSPVTTD----------------QPISP 1712
Query: 1252 QELSPLSATVFPKVEHSPGP---PLADAECQEGLSENSAC----RWTVVKTEEGRQAL-E 1303
+ ++ S + +PG P+ C L S RW V+ E A+ E
Sbjct: 1713 EPITQPSCIKRQRAAGNPGSLAAPIDHKPCSAPLEPKSQASRNQRWGAVRAAESLTAIPE 1772
Query: 1304 PLPQGIQESLNNPTPGDLEEIVKMEPEEAREEISGSPERDICDDIKVEHAVELDTGAPSE 1363
P + E TP +I K+EP R + PE + ++ P +
Sbjct: 1773 PASPQLLE-----TPIHASQIQKVEPA-GRSRFT--PELQPKASQSRKRSLATMDSPPHQ 1824
Query: 1364 ELSSAGEVTKQTVLQKEEERSQPTK 1388
+ GEV+++TV+ KEEE K
Sbjct: 1825 KQPQRGEVSQKTVIIKEEEEDTAEK 1849
Score = 42.7 bits (99), Expect = 0.004
Identities = 122/575 (21%), Positives = 201/575 (34%), Gaps = 85/575 (14%)
Query: 1060 VSGGESFESPAALPAVPPEART--SFPL-SESQTLLSSAPVPKVMLPSLAPSKFR----- 1111
VS G+ A LP PEA PL S+SQ L+ P+ +LPS+ P+ +
Sbjct: 1026 VSRGDQESPDACLPPTVPEAPAPPQKPLNSQSQKHLAPPPLLSPLLPSIKPTVRKTRQDG 1085
Query: 1112 ------------------KPYVRRRPSKRRGVKASPCMKPAPVIHHPASVIFTV-PATTV 1152
KP +R R S R + P AP H S V P T
Sbjct: 1086 SQEAPEAPLSSELEPFHPKPKIRTRKSSR--MTPFPATSAAPEPHPSTSTAQPVTPKPTS 1143
Query: 1153 KIVSLGGGCNMIQPVNAAVAQSPQTIPITTLLVNPTSFPCPLNQSLVASSVSPLIVSGNS 1212
+ + ++ V +P+ P T+ TS P S V+ S +S
Sbjct: 1144 QATRSRTNRSSVKTPEPVVPTAPELQPSTSTDQPVTSEP--------TSQVTRGRKSRSS 1195
Query: 1213 VNLP---IPSTPEDKAHVNVDIACAVADGENAFQGLEPKLEPQELSPLSATVFPKVEHSP 1269
V P +P+ E + + D A +G + + + P+ T P+++ S
Sbjct: 1196 VKTPETVVPTALELQPSTSTDRPVTSEPTSQATRGRKNRSSVKTPEPVVPTA-PELQPST 1254
Query: 1270 GPPLADAECQEGLSENSACRWTVVKTEEGRQALEPLPQGIQESLNNPTPGDLEEIVKME- 1328
Q SE + K + EP+ PT +L +
Sbjct: 1255 STD------QPVTSEPTYQATRGRKNRSSVKTPEPVV---------PTAPELRPSTSTDR 1299
Query: 1329 PEEAREEISGSPERDICDDIKVEHAVELDTGAPSEELSSAGEVTKQTVLQKEEERSQPTK 1388
P + + R +K V AP ++S++ T Q V K R+ ++
Sbjct: 1300 PVTPKPTSRTTRSRTNMSSVKTPETVV--PTAPELQISTS---TDQPVTPKPTSRTTRSR 1354
Query: 1389 TPSSSQEPPDEGTSGTDVNKGSSKNALSSMDPEVRLSSPPGKPEDSSSVDGQSVGTPVGP 1448
T SS + P E T S + + PE + G+ SS +++ P P
Sbjct: 1355 TNMSSVKNP-ESTVPIAPELPPSTSTEQPVTPEPTSRATRGRKNRSSGKTPETL-VPTAP 1412
Query: 1449 ETGGEKNGPEEEEEEDFDDLTQDEEDEMSSASEESVL-SVPELQETMEKLTWLASERRMS 1507
+ + + E T+ + S + E+V+ + PELQ + ++++ ++
Sbjct: 1413 KLEPSTSTDQPVTPEPTSQATRGRTNRSSVKTPETVVPTAPELQPST------STDQPVT 1466
Query: 1508 QEGESEEENSQEENSE---PEEEEEEEAEGMESLQKEDEMTDEAVG---------DSAEK 1555
E S+ + + S PE E S + +T E S +
Sbjct: 1467 PEPTSQATRGRTDRSSVKTPETVVPTAPELQASASTDQPVTSEPTSRTTRGRKNRSSVKT 1526
Query: 1556 PPTF--ASPETAPEVETSRTPPGESIKAAGKGRNN 1588
P T A+PE P T + E A +GR N
Sbjct: 1527 PETVVPAAPELQPSTSTDQPVTPEPTSRATRGRTN 1561
>gi|17975763 myelin transcription factor 1 [Homo sapiens]
Length = 1121
Score = 54.3 bits (129), Expect = 1e-06
Identities = 39/143 (27%), Positives = 66/143 (46%), Gaps = 11/143 (7%)
Query: 1432 EDSSSVDGQSVGTPVGPETGGEKNGPEEEEEEDFDDLTQDEEDEMSSASEESVLSVPELQ 1491
E ++S +G+ G + PE E E +D + ++ S+ ++ +LS E
Sbjct: 203 EGAASEEGEK-GLFIQPEDAEEVVEVTTERSQDLCPQSLEDAASEESSKQKGILSHEEED 261
Query: 1492 ETMEKLTWLASERRMSQEGESEEENSQEENSEPEEEEEEEAEGMESLQKEDEMTDEAVGD 1551
E E+ +E E E+E +EE E EEEEEEE E E ++E+E + A
Sbjct: 262 EEEEE----------EEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEAAPDV 311
Query: 1552 SAEKPPTFASPETAPEVETSRTP 1574
++ + S + APE+ +P
Sbjct: 312 IFQEDTSHTSAQKAPELRGPESP 334
Score = 53.9 bits (128), Expect = 2e-06
Identities = 53/214 (24%), Positives = 85/214 (39%), Gaps = 35/214 (16%)
Query: 1359 GAPSEELSSAGEVTKQTVLQKEEERSQPTKTPSSSQEPPDEGTSGTDVNKGSSKNALSSM 1418
G + L + G++ ++T++ EE+ Q K E G +G +
Sbjct: 162 GIIATSLLNLGQIAEETLV--EEDLGQAAKPGPGIVHLLQEAAEGAASEEGEKGLFIQPE 219
Query: 1419 DPEVRLSSPPGKPEDSSSVDGQSVGTPVGPETGGEKNGPEEEEEEDFDDLTQDEEDEMSS 1478
D E + + +D + + + G + EE+EEE+ ++ ++EEDE
Sbjct: 220 DAEEVVEVTTERSQDLCPQSLEDAASEESSKQKGILSHEEEDEEEE-EEEEEEEEDEEEE 278
Query: 1479 ASEESVLSVPELQETMEKLTWLASERRMSQEGESEEENSQEENSEPEEEEEEEAEGMESL 1538
EE +E E EEE +EE E EEEEEEEA
Sbjct: 279 EEEE-------------------------EEEEEEEEEEEEEEEEEEEEEEEEAAPDVIF 313
Query: 1539 QKEDEMTDEAVGDSAEKPPTFASPET-APEVETS 1571
Q++ T SA+K P PE+ +P+ E S
Sbjct: 314 QEDTSHT------SAQKAPELRGPESPSPKPEYS 341
Score = 43.1 bits (100), Expect = 0.003
Identities = 57/240 (23%), Positives = 91/240 (37%), Gaps = 34/240 (14%)
Query: 1355 ELDTGAPSEELSSAGEVTKQTVLQKEEERSQPTKTPSSSQEPPDEGTSGTDVNKGSSKNA 1414
E GA SEE GE K +Q E+ T SQ+ + + S +
Sbjct: 200 EAAEGAASEE----GE--KGLFIQPEDAEEVVEVTTERSQDLCPQSLEDAASEESSKQKG 253
Query: 1415 LSSMDPEVRLSSPPGKPEDSSSVDGQSVGTPVGPETGGEKNGPEEEEEEDFDDLTQDEED 1474
+ S + E + E+ E E+ EEEEEE+ ++ ++EE+
Sbjct: 254 ILSHEEEDEEEEEEEEEEE---------------EDEEEEEEEEEEEEEEEEEEEEEEEE 298
Query: 1475 EMSSASEESVLSVPELQETMEKLTWLASERRMSQEGESEEENSQEENSEPEEEEEEEAEG 1534
E EE+ V ++T A E R + + E S +++++E+
Sbjct: 299 EEEEEEEEAAPDVIFQEDTSHTSAQKAPELRGPESPSPKPEYSVIVEVRSDDDKDEDTHS 358
Query: 1535 MES-LQKEDEMTD-----------EAVGDSAEKPPTFASPETAPEVETSRTPPGESIKAA 1582
+S + E EM D +A+ AE+ T P P E S+ GE KAA
Sbjct: 359 RKSTVTDESEMQDMMTRGNLGLLEQAIALKAEQVRTVCEP-GCPPAEQSQLGLGEPGKAA 417
Score = 38.9 bits (89), Expect = 0.057
Identities = 35/140 (25%), Positives = 58/140 (41%), Gaps = 4/140 (2%)
Query: 1468 LTQDEEDEMSSASEESVLSVPELQETMEKLTWLASERRMSQ--EGESEEENSQEEN--SE 1523
L + E S E+ + PE E + ++T S+ Q E + EE+S+++ S
Sbjct: 198 LQEAAEGAASEEGEKGLFIQPEDAEEVVEVTTERSQDLCPQSLEDAASEESSKQKGILSH 257
Query: 1524 PEEEEEEEAEGMESLQKEDEMTDEAVGDSAEKPPTFASPETAPEVETSRTPPGESIKAAG 1583
EE+EEEE E E + E+E +E + E+ E E E P +
Sbjct: 258 EEEDEEEEEEEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEAAPDVIFQEDT 317
Query: 1584 KGRNNHRARNKRGSRARASK 1603
+ +A RG + + K
Sbjct: 318 SHTSAQKAPELRGPESPSPK 337
Score = 37.0 bits (84), Expect = 0.22
Identities = 30/129 (23%), Positives = 51/129 (39%), Gaps = 8/129 (6%)
Query: 335 EKGVVIPTWNISPI-----KKANEIKPPQFVDIHLEEDDSSDEEYQPDDEEEDETAEESL 389
EKG+ I + + +++ ++ P D EE ++E+E+E EE
Sbjct: 211 EKGLFIQPEDAEEVVEVTTERSQDLCPQSLEDAASEESSKQKGILSHEEEDEEEEEEEEE 270
Query: 390 LESDVESTASSPRGAKKSRLRQSSEMTETDEESGILSEAEKVTTPAIRHISAEVVP--MG 447
E D E ++ + E E +EE + + + H SA+ P G
Sbjct: 271 EEEDEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEAAPDVIFQEDTSHTSAQKAPELRG 330
Query: 448 P-PPPPKPK 455
P P PKP+
Sbjct: 331 PESPSPKPE 339
Score = 34.7 bits (78), Expect = 1.1
Identities = 52/252 (20%), Positives = 96/252 (38%), Gaps = 36/252 (14%)
Query: 1318 PGDLEEIVKMEPEEAREEISGSPERDICDDIKVEHAVELDTGAPSEELSSAGEVTKQTVL 1377
P D EE+V++ E + +D+C + A SEE S +
Sbjct: 218 PEDAEEVVEVTTERS---------QDLCPQSLED--------AASEESSKQKGILSHEEE 260
Query: 1378 QKEEERSQPTKTPSSSQEPPDEGTSGTDVNKGSSKNALSSMDPEVRLSSPPGKPEDSSSV 1437
+EEE + + +E +E + + + + E + ED+S
Sbjct: 261 DEEEEEEEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEAAPDVIFQEDTSHT 320
Query: 1438 DGQSVGTPVGPETGGEKNGPEEEEEEDFDDLTQDEEDEMSSASEESVLSVPELQETM--- 1494
Q GPE+ P+ E + + D++DE + + + +V E+Q+ M
Sbjct: 321 SAQKAPELRGPES----PSPKPEYSVIVEVRSDDDKDEDTHSRKSTVTDESEMQDMMTRG 376
Query: 1495 -----EKLTWLASE--RRMSQEGESEEENSQEENSEPEEEEEEEAEGMESLQKEDEMTDE 1547
E+ L +E R + + G E SQ EP + A+ +++++K D
Sbjct: 377 NLGLLEQAIALKAEQVRTVCEPGCPPAEQSQLGLGEP----GKAAKPLDTVRKSYYSKDP 432
Query: 1548 AVGDSAE-KPPT 1558
+ + E K PT
Sbjct: 433 SRAEKREIKCPT 444
>gi|16445033 ACRC protein [Homo sapiens]
Length = 691
Score = 54.3 bits (129), Expect = 1e-06
Identities = 70/348 (20%), Positives = 140/348 (40%), Gaps = 24/348 (6%)
Query: 1299 RQALEPLPQGIQESLNNPTPGDLEEIV--KMEPEEAREEISGSPER--DICDDIKVEHAV 1354
+ A++ P I + N+ G+ E+ + EA ++ S E D DD +
Sbjct: 113 KPAIQEPPIVISDDDNDDDNGNDLEVPDDNSDDSEAPDDNSDDSEAPDDNSDDSEAPDDN 172
Query: 1355 ELDTGAPSEELSSAGEVTKQTVLQKEEERSQPTKTPSSSQEPPDEGTSGTDVNKGSSKNA 1414
D+ AP + + + ++ + S + PD+ + +DV SS ++
Sbjct: 173 SDDSEAPDDNSDDSDVPDDNSDDSSDDNSDDSSDDNSDDSDVPDDKSDDSDVPDDSSDDS 232
Query: 1415 LSSMDPEVRLSSPPGKPEDSSSVDGQSVGTPVGPETGGEKNGPEE--EEEEDFDDLTQDE 1472
D +P +DS + D S + ++ + P++ ++ E DD + D
Sbjct: 233 DVPDDSSDDSEAPDDSSDDSEAPDDSSDDSEAPDDSSDDSEAPDDSSDDSEASDDSSDDS 292
Query: 1473 E--DEMSSASE--ESVLSVPELQETMEKLTWLASERRMSQEGESEEENSQEENSEPEEEE 1528
E D+ S SE + ++ E + + + E E+ E +EE
Sbjct: 293 EASDDSSDDSEAPDDKSDDSDVPEDKSDDSDVPDDNSDDLEVPVPAEDLCNEGQIASDEE 352
Query: 1529 E--EEAEGMESLQKEDEMTDEAVGDSAEKPPTFASPETAPEVETSRTP----PGESIKAA 1582
E E A + D+ ++ +G++ KPP + PE PEV + P P ++ +
Sbjct: 353 ELVEAAAAVSQHDSSDDAGEQDLGENLSKPP--SDPEANPEVSERKLPTEEEPAPVVEQS 410
Query: 1583 GKGRNNHRA----RNKRGSRARASKDTSKLLLLYDEDILERDPLREQK 1626
GK ++ + KR ++ + + + ++I+E PLR++K
Sbjct: 411 GKRKSKTKTIVEPPRKRQTKTKNIVEPPRKRQTKTKNIVE--PLRKRK 456
Score = 43.9 bits (102), Expect = 0.002
Identities = 41/246 (16%), Positives = 101/246 (41%), Gaps = 17/246 (6%)
Query: 1335 EISGSPERDICDDIKVEHAVELDTGAPSEELSSAGEVTKQTVLQKEEERSQPTKTPSSSQ 1394
+ SGS + V +D+ + E + + K + ++E + + Q
Sbjct: 58 DTSGSSVARRAPKRQASSVVVIDSDSDEECHTHEEKKAKLLEINSDDESPECCHVKPAIQ 117
Query: 1395 EPP---------DEGTSGTDVNKGSSKNALSSMDPEVRLSSPPGKPEDSSSVDGQSVGTP 1445
EPP D+ + +V +S ++ + D +P +DS + D S +
Sbjct: 118 EPPIVISDDDNDDDNGNDLEVPDDNSDDSEAPDDNSDDSEAPDDNSDDSEAPDDNSDDSE 177
Query: 1446 VGPETGGEKNGPEEEEEEDFDDLTQDEEDEMSSASEESVLSVPELQETMEKLTWLASERR 1505
+ + + P++ ++ DD + D D+ S S+ VP+ + + +S+
Sbjct: 178 APDDNSDDSDVPDDNSDDSSDDNSDDSSDDNSDDSD-----VPDDKSDDSDVPDDSSDDS 232
Query: 1506 MSQEGESEEENSQEENSEPEEEEEEEAEGMESLQKEDEMTDEAVGDSAEKPPTFASPETA 1565
+ S++ + +++S+ E ++ ++ E+ D+ +D++ + AS +++
Sbjct: 233 DVPDDSSDDSEAPDDSSDDSEAPDDSSDDSEA---PDDSSDDSEAPDDSSDDSEASDDSS 289
Query: 1566 PEVETS 1571
+ E S
Sbjct: 290 DDSEAS 295
Score = 33.9 bits (76), Expect = 1.8
Identities = 65/333 (19%), Positives = 124/333 (37%), Gaps = 35/333 (10%)
Query: 367 DDSSDEEYQPDDEEED-ETAEESLLESDVESTASSPRGAKKSRLRQSSEMTETDEESGIL 425
DD+SD+ PDD +D E +++ +S+ S SS+ D
Sbjct: 150 DDNSDDSEAPDDNSDDSEAPDDNSDDSEAPDDNSDDSDVPDDNSDDSSDDNSDDSSD--- 206
Query: 426 SEAEKVTTPAIRHISAEVVPMGPPPPPKPKQTRDSTFMEKLHAVDEELASSPVCMDSFQP 485
++ P + ++V P + D + A D+ S DS
Sbjct: 207 DNSDDSDVPDDKSDDSDVPDDSSDDSDVPDDSSDDS-----EAPDDSSDDSEAPDDS--- 258
Query: 486 MDDSLIAFRTRSKMPLKDVPLGQLEAELQAPD---ITPDMYDPNTADDEDWKMWLGGLMN 542
DDS + D EA + D + D D + A D+ +
Sbjct: 259 SDDSEAPDDSSDDSEAPDDSSDDSEASDDSSDDSEASDDSSDDSEAPDDK--------SD 310
Query: 543 DDVGNEDEADDDDDPEYNFLEDLDEP-DTEDFRTDRAVRITKKEVNELMEELFETFQDEM 601
D ED++DD D P+ N +DL+ P ED + + ++E+ E + + D
Sbjct: 311 DSDVPEDKSDDSDVPDDN-SDDLEVPVPAEDLCNEGQIASDEEELVEAAAAVSQ--HDSS 367
Query: 602 GFSNMEDDGPEEEECVAEPRPNFN-TPQALRFEE---PLANLLNEQHRTVKELFEQLKMK 657
+ +D G + ++P N + + L EE P+ ++ K + E + +
Sbjct: 368 DDAGEQDLGENLSKPPSDPEANPEVSERKLPTEEEPAPVVEQSGKRKSKTKTIVEPPRKR 427
Query: 658 KSSAKQLQEVEKVKPQSEKVHQTLILDPAQRKR 690
++ K + E P+ + I++P ++++
Sbjct: 428 QTKTKNIVE----PPRKRQTKTKNIVEPLRKRK 456
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.309 0.128 0.366
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 100,686,118
Number of Sequences: 37866
Number of extensions: 5687125
Number of successful extensions: 60397
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 434
Number of HSP's successfully gapped in prelim test: 1313
Number of HSP's that attempted gapping in prelim test: 29936
Number of HSP's gapped (non-prelim): 19479
length of query: 2240
length of database: 18,247,518
effective HSP length: 118
effective length of query: 2122
effective length of database: 13,779,330
effective search space: 29239738260
effective search space used: 29239738260
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.7 bits)
S2: 70 (31.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.