Guide to the Human Genome
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Name: POMC Sequence: fasta or formatted (267aa) NCBI GI: 80861463
Description:

proopiomelanocortin preproprotein

Referenced in:

Adrenals
Proteins Measured in Common Diagnostic Tests
Hypothalamus
Peptide and Protein G-coupled Signals
Pituitary

Other entries for this name:
alt mRNA [267aa] proopiomelanocortin preproprotein
Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             7.1         19           2
 C cysteine            2.6          7           2
 D aspartate           5.6         15           2
 E glutamate           9.4         25           1
 F phenylalanine       3.4          9           1
 G glycine            11.2         30           2
 H histidine           1.5          4           1
 I isoleucine          1.1          3           2
 K lysine              7.1         19           2
 L leucine             7.9         21           3
 M methionine          2.6          7           1
 N asparagine          2.6          7           1
 P proline             8.2         22           2
 Q glutamine           3.0          8           1
 R arginine            8.2         22           2
 S serine              8.6         23           4
 T threonine           3.0          8           2
 V valine              3.0          8           1
 W tryptophan          1.5          4           1
 Y tyrosine            2.2          6           1
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   proopiomelanocortin preproprotein 
POMC                  1.000   proopiomelanocortin preproprotein 
CHD3                  0.024   chromodomain helicase DNA binding protein 3 isoform ...
CHD3                  0.024   chromodomain helicase DNA binding protein 3 isoform ...
CHD3                  0.024   chromodomain helicase DNA binding protein 3 isoform...
LOC100132015          0.022   PREDICTED: similar to testis expressed sequence 13A...
PRB1                  0.021   proline-rich protein BstNI subfamily 1 isoform 3 pre...
PRB1                  0.021   proline-rich protein BstNI subfamily 1 isoform 1 pre...
UNC93B1               0.019   unc-93 homolog B1 
PRB2                  0.019   proline-rich protein BstNI subfamily 2 
LOC100287293          0.017   PREDICTED: hypothetical protein XP_002343924 
MYO18B                0.015   myosin XVIIIB 
PRB1                  0.015   proline-rich protein BstNI subfamily 1 isoform 2 pre...
MSX2                  0.013   msh homeobox 2 
LOC100290504          0.013   PREDICTED: hypothetical protein XP_002346416 
SETD1B                0.013   SET domain containing 1B 
CABIN1                0.013   calcineurin binding protein 1 
DMKN                  0.013   dermokine isoform 4 precursor 
DMKN                  0.013   dermokine isoform 5 precursor 
DMKN                  0.013   dermokine isoform 3 precursor 
DMKN                  0.013   dermokine isoform 2 precursor 
LOC729196             0.013   PREDICTED: similar to unc-93 homolog B1 (C. elegans...
LOC729196             0.013   PREDICTED: similar to unc-93 homolog B1 (C. elegans...
LOC729196             0.013   PREDICTED: similar to unc-93 homolog B1 (C. elegans...
RREB1                 0.013   ras responsive element binding protein 1 isoform 2 [...
RREB1                 0.013   ras responsive element binding protein 1 isoform 1 [...
MYPOP                 0.013   Myb protein P42POP 
ZNF444                0.013   zinc finger protein 444 
GAK                   0.011   cyclin G associated kinase 
PHF14                 0.011   PHD finger protein 14 isoform 2 
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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