Guide to the Human Genome
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Search of human proteins with 78482627

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|78482627 ring finger protein 30 isoform 1 [Homo sapiens]
         (400 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|78482627 ring finger protein 30 isoform 1 [Homo sapiens]           808   0.0  
gi|78482626 ring finger protein 30 isoform 2 [Homo sapiens]           704   0.0  
gi|34878844 tripartite motif-containing 55 isoform 3 [Homo sapiens]   435   e-122
gi|34878836 tripartite motif-containing 55 isoform 1 [Homo sapiens]   435   e-122
gi|34878821 tripartite motif-containing 55 isoform 2 [Homo sapiens]   435   e-122
gi|19924163 muscle specific ring finger protein 1 [Homo sapiens]      406   e-113
gi|34878852 tripartite motif-containing 55 isoform 4 [Homo sapiens]   307   1e-83
gi|62865606 tripartite motif-containing 36 isoform 1 [Homo sapiens]   130   2e-30
gi|148833499 midline 1 [Homo sapiens]                                 126   4e-29
gi|4557753 midline 1 [Homo sapiens]                                   126   4e-29
gi|15451852 midline 1 [Homo sapiens]                                  126   4e-29
gi|223890259 midline 2 isoform 2 [Homo sapiens]                       125   7e-29
gi|223890257 midline 2 isoform 1 [Homo sapiens]                       125   7e-29
gi|47174859 tripartite motif-containing 46 [Homo sapiens]             124   1e-28
gi|27436877 tripartite motif-containing 59 [Homo sapiens]              88   1e-17
gi|32454739 tripartite motif-containing 3 [Homo sapiens]               87   3e-17
gi|32454737 tripartite motif-containing 3 [Homo sapiens]               87   3e-17
gi|55953112 ret finger protein 2 isoform 2 [Homo sapiens]              86   8e-17
gi|47132524 ret finger protein 2 isoform 1 [Homo sapiens]              86   8e-17
gi|16445412 ret finger protein 2 isoform 1 [Homo sapiens]              86   8e-17
gi|47132521 ret finger protein 2 isoform 1 [Homo sapiens]              86   8e-17
gi|194248081 tripartite motif-containing 2 isoform 2 [Homo sapiens]    78   2e-14
gi|194248079 tripartite motif-containing 2 isoform 1 [Homo sapiens]    78   2e-14
gi|134288906 tripartite motif-containing 67 [Homo sapiens]             77   3e-14
gi|55741632 fibronectin type III and SPRY domain containing 2 [H...    76   5e-14
gi|14670266 tripartite motif protein TRIM4 isoform alpha [Homo s...    67   3e-11
gi|89886468 fibronectin type III and SPRY domain containing 1-li...    67   3e-11
gi|223718222 fibronectin type III and SPRY domain containing 1-l...    67   3e-11
gi|145275183 tripartite motif protein 34 isoform 3 [Homo sapiens]      66   6e-11
gi|51477687 tripartite motif protein 34 isoform 1 [Homo sapiens]       66   6e-11

>gi|78482627 ring finger protein 30 isoform 1 [Homo sapiens]
          Length = 400

 Score =  808 bits (2087), Expect = 0.0
 Identities = 400/400 (100%), Positives = 400/400 (100%)

Query: 1   MNFTVGFKPLLGDAHSMDNLEKQLICPICLEMFSKPVVILPCQHNLCRKCANDVFQASNP 60
           MNFTVGFKPLLGDAHSMDNLEKQLICPICLEMFSKPVVILPCQHNLCRKCANDVFQASNP
Sbjct: 1   MNFTVGFKPLLGDAHSMDNLEKQLICPICLEMFSKPVVILPCQHNLCRKCANDVFQASNP 60

Query: 61  LWQSRGSTTVSSGGRFRCPSCRHEVVLDRHGVYGLQRNLLVENIIDIYKQESSRPLHSKA 120
           LWQSRGSTTVSSGGRFRCPSCRHEVVLDRHGVYGLQRNLLVENIIDIYKQESSRPLHSKA
Sbjct: 61  LWQSRGSTTVSSGGRFRCPSCRHEVVLDRHGVYGLQRNLLVENIIDIYKQESSRPLHSKA 120

Query: 121 EQHLMCEEHEEEKINIYCLSCEVPTCSLCKVFGAHKDCEVAPLPTIYKRQKKQDLTLLPR 180
           EQHLMCEEHEEEKINIYCLSCEVPTCSLCKVFGAHKDCEVAPLPTIYKRQKKQDLTLLPR
Sbjct: 121 EQHLMCEEHEEEKINIYCLSCEVPTCSLCKVFGAHKDCEVAPLPTIYKRQKKQDLTLLPR 180

Query: 181 LECSGTNTTYCSLDLPSSSDPPILASQNTKIIDSELSDGIAMLVAGNDRVQAVITQMEEV 240
           LECSGTNTTYCSLDLPSSSDPPILASQNTKIIDSELSDGIAMLVAGNDRVQAVITQMEEV
Sbjct: 181 LECSGTNTTYCSLDLPSSSDPPILASQNTKIIDSELSDGIAMLVAGNDRVQAVITQMEEV 240

Query: 241 CQTIEDNSRRQKQLLNQRFESLCAVLEERKGELLQALAREQEEKLQRVRGLIRQYGDHLE 300
           CQTIEDNSRRQKQLLNQRFESLCAVLEERKGELLQALAREQEEKLQRVRGLIRQYGDHLE
Sbjct: 241 CQTIEDNSRRQKQLLNQRFESLCAVLEERKGELLQALAREQEEKLQRVRGLIRQYGDHLE 300

Query: 301 ASSKLVESAIQSMEEPQMALYLQQAKELINKVGAMSKVELAGRPEPGYESMEQFTVRVEH 360
           ASSKLVESAIQSMEEPQMALYLQQAKELINKVGAMSKVELAGRPEPGYESMEQFTVRVEH
Sbjct: 301 ASSKLVESAIQSMEEPQMALYLQQAKELINKVGAMSKVELAGRPEPGYESMEQFTVRVEH 360

Query: 361 VAEMLRTIDFQPGASGEEEEVAPDGEEGSAGPEEERPDGP 400
           VAEMLRTIDFQPGASGEEEEVAPDGEEGSAGPEEERPDGP
Sbjct: 361 VAEMLRTIDFQPGASGEEEEVAPDGEEGSAGPEEERPDGP 400


>gi|78482626 ring finger protein 30 isoform 2 [Homo sapiens]
          Length = 358

 Score =  704 bits (1816), Expect = 0.0
 Identities = 358/400 (89%), Positives = 358/400 (89%), Gaps = 42/400 (10%)

Query: 1   MNFTVGFKPLLGDAHSMDNLEKQLICPICLEMFSKPVVILPCQHNLCRKCANDVFQASNP 60
           MNFTVGFKPLLGDAHSMDNLEKQLICPICLEMFSKPVVILPCQHNLCRKCANDVFQASNP
Sbjct: 1   MNFTVGFKPLLGDAHSMDNLEKQLICPICLEMFSKPVVILPCQHNLCRKCANDVFQASNP 60

Query: 61  LWQSRGSTTVSSGGRFRCPSCRHEVVLDRHGVYGLQRNLLVENIIDIYKQESSRPLHSKA 120
           LWQSRGSTTVSSGGRFRCPSCRHEVVLDRHGVYGLQRNLLVENIIDIYKQESSRPLHSKA
Sbjct: 61  LWQSRGSTTVSSGGRFRCPSCRHEVVLDRHGVYGLQRNLLVENIIDIYKQESSRPLHSKA 120

Query: 121 EQHLMCEEHEEEKINIYCLSCEVPTCSLCKVFGAHKDCEVAPLPTIYKRQKKQDLTLLPR 180
           EQHLMCEEHEEEKINIYCLSCEVPTCSLCKVFGAHKDCEVAPLPTIYKRQK         
Sbjct: 121 EQHLMCEEHEEEKINIYCLSCEVPTCSLCKVFGAHKDCEVAPLPTIYKRQK--------- 171

Query: 181 LECSGTNTTYCSLDLPSSSDPPILASQNTKIIDSELSDGIAMLVAGNDRVQAVITQMEEV 240
                                            SELSDGIAMLVAGNDRVQAVITQMEEV
Sbjct: 172 ---------------------------------SELSDGIAMLVAGNDRVQAVITQMEEV 198

Query: 241 CQTIEDNSRRQKQLLNQRFESLCAVLEERKGELLQALAREQEEKLQRVRGLIRQYGDHLE 300
           CQTIEDNSRRQKQLLNQRFESLCAVLEERKGELLQALAREQEEKLQRVRGLIRQYGDHLE
Sbjct: 199 CQTIEDNSRRQKQLLNQRFESLCAVLEERKGELLQALAREQEEKLQRVRGLIRQYGDHLE 258

Query: 301 ASSKLVESAIQSMEEPQMALYLQQAKELINKVGAMSKVELAGRPEPGYESMEQFTVRVEH 360
           ASSKLVESAIQSMEEPQMALYLQQAKELINKVGAMSKVELAGRPEPGYESMEQFTVRVEH
Sbjct: 259 ASSKLVESAIQSMEEPQMALYLQQAKELINKVGAMSKVELAGRPEPGYESMEQFTVRVEH 318

Query: 361 VAEMLRTIDFQPGASGEEEEVAPDGEEGSAGPEEERPDGP 400
           VAEMLRTIDFQPGASGEEEEVAPDGEEGSAGPEEERPDGP
Sbjct: 319 VAEMLRTIDFQPGASGEEEEVAPDGEEGSAGPEEERPDGP 358


>gi|34878844 tripartite motif-containing 55 isoform 3 [Homo sapiens]
          Length = 452

 Score =  435 bits (1119), Expect = e-122
 Identities = 225/396 (56%), Positives = 273/396 (68%), Gaps = 47/396 (11%)

Query: 1   MNFTVGFKPLLGDAHSMDNLEKQLICPICLEMFSKPVVILPCQHNLCRKCANDVFQASNP 60
           M+ ++ +K    +  +MDNLEKQLICPICLEMF+KPVVILPCQHNLCRKCA+D+FQASNP
Sbjct: 1   MSASLNYKSFSKEQQTMDNLEKQLICPICLEMFTKPVVILPCQHNLCRKCASDIFQASNP 60

Query: 61  LWQSRGSTTVSSGGRFRCPSCRHEVVLDRHGVYGLQRNLLVENIIDIYKQESSRPLHSKA 120
              +RG TT++SGGRFRCPSCRHEVVLDRHGVYGLQRNLLVENIIDIYKQES+RP   K 
Sbjct: 61  YLPTRGGTTMASGGRFRCPSCRHEVVLDRHGVYGLQRNLLVENIIDIYKQESTRP--EKK 118

Query: 121 EQHLMCEEHEEEKINIYCLSCEVPTCSLCKVFGAHKDCEVAPLPTIYKRQKKQDLTLLPR 180
               MCEEHEEE+INIYCL+CEVPTCSLCKVFGAHKDC+VAPL  +++RQK         
Sbjct: 119 SDQPMCEEHEEERINIYCLNCEVPTCSLCKVFGAHKDCQVAPLTHVFQRQK--------- 169

Query: 181 LECSGTNTTYCSLDLPSSSDPPILASQNTKIIDSELSDGIAMLVAGNDRVQAVITQMEEV 240
                                            SELSDGIA+LV  NDRVQ VI+Q+E+ 
Sbjct: 170 ---------------------------------SELSDGIAILVGSNDRVQGVISQLEDT 196

Query: 241 CQTIEDNSRRQKQLLNQRFESLCAVLEERKGELLQALAREQEEKLQRVRGLIRQYGDHLE 300
           C+TIE+  R+QKQ L ++F+ L  +LEERK E+ Q + R QEEKL+ VR LI++Y DHLE
Sbjct: 197 CKTIEECCRKQKQELCEKFDYLYGILEERKNEMTQVITRTQEEKLEHVRALIKKYSDHLE 256

Query: 301 ASSKLVESAIQSMEEPQMALYLQQAKELINKVGAMSKVELAGRPEPGYESMEQFTVRVEH 360
             SKLVES IQ M+EP+MA++LQ AK L+ K+   SK     + E GYE+M  FTV +  
Sbjct: 257 NVSKLVESGIQFMDEPEMAVFLQNAKTLLKKISEASKAFQMEKIEHGYENMNHFTVNLNR 316

Query: 361 VAEMLRTIDFQPGASGEEEEVAPDGE---EGSAGPE 393
             +++R IDF      EEEE   +GE   EG  G E
Sbjct: 317 EEKIIREIDFYREDEDEEEEEGGEGEKEGEGEVGGE 352


>gi|34878836 tripartite motif-containing 55 isoform 1 [Homo sapiens]
          Length = 548

 Score =  435 bits (1119), Expect = e-122
 Identities = 225/396 (56%), Positives = 273/396 (68%), Gaps = 47/396 (11%)

Query: 1   MNFTVGFKPLLGDAHSMDNLEKQLICPICLEMFSKPVVILPCQHNLCRKCANDVFQASNP 60
           M+ ++ +K    +  +MDNLEKQLICPICLEMF+KPVVILPCQHNLCRKCA+D+FQASNP
Sbjct: 1   MSASLNYKSFSKEQQTMDNLEKQLICPICLEMFTKPVVILPCQHNLCRKCASDIFQASNP 60

Query: 61  LWQSRGSTTVSSGGRFRCPSCRHEVVLDRHGVYGLQRNLLVENIIDIYKQESSRPLHSKA 120
              +RG TT++SGGRFRCPSCRHEVVLDRHGVYGLQRNLLVENIIDIYKQES+RP   K 
Sbjct: 61  YLPTRGGTTMASGGRFRCPSCRHEVVLDRHGVYGLQRNLLVENIIDIYKQESTRP--EKK 118

Query: 121 EQHLMCEEHEEEKINIYCLSCEVPTCSLCKVFGAHKDCEVAPLPTIYKRQKKQDLTLLPR 180
               MCEEHEEE+INIYCL+CEVPTCSLCKVFGAHKDC+VAPL  +++RQK         
Sbjct: 119 SDQPMCEEHEEERINIYCLNCEVPTCSLCKVFGAHKDCQVAPLTHVFQRQK--------- 169

Query: 181 LECSGTNTTYCSLDLPSSSDPPILASQNTKIIDSELSDGIAMLVAGNDRVQAVITQMEEV 240
                                            SELSDGIA+LV  NDRVQ VI+Q+E+ 
Sbjct: 170 ---------------------------------SELSDGIAILVGSNDRVQGVISQLEDT 196

Query: 241 CQTIEDNSRRQKQLLNQRFESLCAVLEERKGELLQALAREQEEKLQRVRGLIRQYGDHLE 300
           C+TIE+  R+QKQ L ++F+ L  +LEERK E+ Q + R QEEKL+ VR LI++Y DHLE
Sbjct: 197 CKTIEECCRKQKQELCEKFDYLYGILEERKNEMTQVITRTQEEKLEHVRALIKKYSDHLE 256

Query: 301 ASSKLVESAIQSMEEPQMALYLQQAKELINKVGAMSKVELAGRPEPGYESMEQFTVRVEH 360
             SKLVES IQ M+EP+MA++LQ AK L+ K+   SK     + E GYE+M  FTV +  
Sbjct: 257 NVSKLVESGIQFMDEPEMAVFLQNAKTLLKKISEASKAFQMEKIEHGYENMNHFTVNLNR 316

Query: 361 VAEMLRTIDFQPGASGEEEEVAPDGE---EGSAGPE 393
             +++R IDF      EEEE   +GE   EG  G E
Sbjct: 317 EEKIIREIDFYREDEDEEEEEGGEGEKEGEGEVGGE 352


>gi|34878821 tripartite motif-containing 55 isoform 2 [Homo sapiens]
          Length = 540

 Score =  435 bits (1119), Expect = e-122
 Identities = 225/396 (56%), Positives = 273/396 (68%), Gaps = 47/396 (11%)

Query: 1   MNFTVGFKPLLGDAHSMDNLEKQLICPICLEMFSKPVVILPCQHNLCRKCANDVFQASNP 60
           M+ ++ +K    +  +MDNLEKQLICPICLEMF+KPVVILPCQHNLCRKCA+D+FQASNP
Sbjct: 1   MSASLNYKSFSKEQQTMDNLEKQLICPICLEMFTKPVVILPCQHNLCRKCASDIFQASNP 60

Query: 61  LWQSRGSTTVSSGGRFRCPSCRHEVVLDRHGVYGLQRNLLVENIIDIYKQESSRPLHSKA 120
              +RG TT++SGGRFRCPSCRHEVVLDRHGVYGLQRNLLVENIIDIYKQES+RP   K 
Sbjct: 61  YLPTRGGTTMASGGRFRCPSCRHEVVLDRHGVYGLQRNLLVENIIDIYKQESTRP--EKK 118

Query: 121 EQHLMCEEHEEEKINIYCLSCEVPTCSLCKVFGAHKDCEVAPLPTIYKRQKKQDLTLLPR 180
               MCEEHEEE+INIYCL+CEVPTCSLCKVFGAHKDC+VAPL  +++RQK         
Sbjct: 119 SDQPMCEEHEEERINIYCLNCEVPTCSLCKVFGAHKDCQVAPLTHVFQRQK--------- 169

Query: 181 LECSGTNTTYCSLDLPSSSDPPILASQNTKIIDSELSDGIAMLVAGNDRVQAVITQMEEV 240
                                            SELSDGIA+LV  NDRVQ VI+Q+E+ 
Sbjct: 170 ---------------------------------SELSDGIAILVGSNDRVQGVISQLEDT 196

Query: 241 CQTIEDNSRRQKQLLNQRFESLCAVLEERKGELLQALAREQEEKLQRVRGLIRQYGDHLE 300
           C+TIE+  R+QKQ L ++F+ L  +LEERK E+ Q + R QEEKL+ VR LI++Y DHLE
Sbjct: 197 CKTIEECCRKQKQELCEKFDYLYGILEERKNEMTQVITRTQEEKLEHVRALIKKYSDHLE 256

Query: 301 ASSKLVESAIQSMEEPQMALYLQQAKELINKVGAMSKVELAGRPEPGYESMEQFTVRVEH 360
             SKLVES IQ M+EP+MA++LQ AK L+ K+   SK     + E GYE+M  FTV +  
Sbjct: 257 NVSKLVESGIQFMDEPEMAVFLQNAKTLLKKISEASKAFQMEKIEHGYENMNHFTVNLNR 316

Query: 361 VAEMLRTIDFQPGASGEEEEVAPDGE---EGSAGPE 393
             +++R IDF      EEEE   +GE   EG  G E
Sbjct: 317 EEKIIREIDFYREDEDEEEEEGGEGEKEGEGEVGGE 352


>gi|19924163 muscle specific ring finger protein 1 [Homo sapiens]
          Length = 353

 Score =  406 bits (1043), Expect = e-113
 Identities = 210/388 (54%), Positives = 272/388 (70%), Gaps = 47/388 (12%)

Query: 10  LLGDAHSMDNLEKQLICPICLEMFSKPVVILPCQHNLCRKCANDVFQASNPLWQSRGSTT 69
           L+ D + M+NLEKQLICPICLEMF+KPVVILPCQHNLCRKCAND+FQA+NP W SRGS+ 
Sbjct: 7   LIQDGNPMENLEKQLICPICLEMFTKPVVILPCQHNLCRKCANDIFQAANPYWTSRGSSV 66

Query: 70  VSSGGRFRCPSCRHEVVLDRHGVYGLQRNLLVENIIDIYKQE-SSRPLHSKAEQHLMCEE 128
             SGGRFRCP+CRHEV++DRHGVYGLQRNLLVENIIDIYKQE SSRPL   +  H MC+E
Sbjct: 67  SMSGGRFRCPTCRHEVIMDRHGVYGLQRNLLVENIIDIYKQECSSRPLQKGS--HPMCKE 124

Query: 129 HEEEKINIYCLSCEVPTCSLCKVFGAHKDCEVAPLPTIYKRQKKQDLTLLPRLECSGTNT 188
           HE+EKINIYCL+CEVPTCS+CKVFG HK CEVAPL ++++ QK                 
Sbjct: 125 HEDEKINIYCLTCEVPTCSMCKVFGIHKACEVAPLQSVFQGQK----------------- 167

Query: 189 TYCSLDLPSSSDPPILASQNTKIIDSELSDGIAMLVAGNDRVQAVITQMEEVCQTIEDNS 248
                                    +EL++ I+MLVAGNDRVQ +ITQ+E+  +  ++NS
Sbjct: 168 -------------------------TELNNCISMLVAGNDRVQTIITQLEDSRRVTKENS 202

Query: 249 RRQKQLLNQRFESLCAVLEERKGELLQALAREQEEKLQRVRGLIRQYGDHLEASSKLVES 308
            + K+ L+Q+F++L A+L+E+K ELLQ + +EQE+KL  +  LI+QY + L+ S+KLVE+
Sbjct: 203 HQVKEELSQKFDTLYAILDEKKSELLQRITQEQEKKLSFIEALIQQYQEQLDKSTKLVET 262

Query: 309 AIQSMEEPQMALYLQQAKELINKVGAMSKVELAGRPEPGYESMEQFTVRVEHVAEMLRTI 368
           AIQS++EP  A +L  AK+LI  +   SK    G+ E G+E+M+ FT+ +EH+A+ LR I
Sbjct: 263 AIQSLDEPGGATFLLTAKQLIKSIVEASKGCQLGKTEQGFENMDFFTLDLEHIADALRAI 322

Query: 369 DFQPGASGEE--EEVAPDGEEGSAGPEE 394
           DF      EE  EE   + EE + G EE
Sbjct: 323 DFGTDEEEEEFIEEEDQEEEESTEGKEE 350


>gi|34878852 tripartite motif-containing 55 isoform 4 [Homo sapiens]
          Length = 241

 Score =  307 bits (786), Expect = 1e-83
 Identities = 153/245 (62%), Positives = 177/245 (72%), Gaps = 44/245 (17%)

Query: 1   MNFTVGFKPLLGDAHSMDNLEKQLICPICLEMFSKPVVILPCQHNLCRKCANDVFQASNP 60
           M+ ++ +K    +  +MDNLEKQLICPICLEMF+KPVVILPCQHNLCRKCA+D+FQASNP
Sbjct: 1   MSASLNYKSFSKEQQTMDNLEKQLICPICLEMFTKPVVILPCQHNLCRKCASDIFQASNP 60

Query: 61  LWQSRGSTTVSSGGRFRCPSCRHEVVLDRHGVYGLQRNLLVENIIDIYKQESSRPLHSKA 120
              +RG TT++SGGRFRCPSCRHEVVLDRHGVYGLQRNLLVENIIDIYKQES+RP   K 
Sbjct: 61  YLPTRGGTTMASGGRFRCPSCRHEVVLDRHGVYGLQRNLLVENIIDIYKQESTRP--EKK 118

Query: 121 EQHLMCEEHEEEKINIYCLSCEVPTCSLCKVFGAHKDCEVAPLPTIYKRQKKQDLTLLPR 180
               MCEEHEEE+INIYCL+CEVPTCSLCKVFGAHKDC+VAPL  +++RQK         
Sbjct: 119 SDQPMCEEHEEERINIYCLNCEVPTCSLCKVFGAHKDCQVAPLTHVFQRQK--------- 169

Query: 181 LECSGTNTTYCSLDLPSSSDPPILASQNTKIIDSELSDGIAMLVAGNDRVQAVITQMEEV 240
                                            SELSDGIA+LV  NDRVQ VI+Q+E+ 
Sbjct: 170 ---------------------------------SELSDGIAILVGSNDRVQGVISQLEDT 196

Query: 241 CQTIE 245
           C+TIE
Sbjct: 197 CKTIE 201


>gi|62865606 tripartite motif-containing 36 isoform 1 [Homo sapiens]
          Length = 728

 Score =  130 bits (327), Expect = 2e-30
 Identities = 112/469 (23%), Positives = 188/469 (40%), Gaps = 131/469 (27%)

Query: 16  SMDNLEKQLICPICLEMFSKPVVILPCQHNLCRKCANDVFQASNPLWQSRGSTTVSSGGR 75
           ++ N+E++LICP C E+F+ P+ ILPCQH++C KC  ++    +  +   GS   +    
Sbjct: 23  TIKNIERELICPACKELFTHPL-ILPCQHSICHKCVKELLLTLDDSFNDVGSDNSNQSSP 81

Query: 76  -------------------------------FRCPSCRHEVVLDRHGVYGLQRNLLVENI 104
                                          F CP C H+V L   G+ GL RN  +E I
Sbjct: 82  RLRLPSPSMDKIDRINRPGWKRNSLTPRTTVFPCPGCEHDVDLGERGINGLFRNFTLETI 141

Query: 105 IDIYKQ------------------ESSR------------------PLHSKAEQH----- 123
           ++ Y+Q                  ES++                  P  +   QH     
Sbjct: 142 VERYRQAARAATAIMCDLCKPPPQESTKSCMDCSASYCNECFKIHHPWGTIKAQHEYVGP 201

Query: 124 --------LMCEEHEEEKINIYCLSCEVPTCSLCKVFGAHKDCEVAPLPTIYKRQKKQDL 175
                   LMC EHE E+IN+YC  C  P C LCK+ G H +  V  + + YK  K++  
Sbjct: 202 TTNFRPKILMCPEHETERINMYCELCRRPVCHLCKLGGNHANHRVTTMSSAYKTLKEK-- 259

Query: 176 TLLPRLECSGTNTTYCSLDLPSSSDPPILASQNTKIIDSELSDGIAMLVAGNDRVQAVIT 235
                                                   LS  I  L+    +V++ I+
Sbjct: 260 ----------------------------------------LSKDIDYLIGKESQVKSQIS 279

Query: 236 QMEEVCQTIEDNSRRQKQLLNQRFESLCAVLEERKGELLQALAREQEEKLQRVRGLIRQY 295
           ++  + +  E N  R K+     FE L  VLEERK  +L+A+   ++ +L + +  + +Y
Sbjct: 280 ELNLLMKETECNGERAKEEAITHFEKLFEVLEERKSSVLKAIDSSKKLRLDKFQTQMEEY 339

Query: 296 GDHLEASSKLVESAIQSMEEPQMALYLQQAKELINKVGAMSKVELAGRPEPGYESMEQFT 355
              LE ++ LV  A + ++E   + ++Q AK+L  ++   ++   + RP     S E + 
Sbjct: 340 QGLLE-NNGLVGYAQEVLKETDQSCFVQTAKQLHLRIQKATESLKSFRP-AAQTSFEDYV 397

Query: 356 VRVEHVAEMLRTIDF------QPGASGEEEEVAPDGEEGSAGPEEERPD 398
           V      E+L  + F       P  + E+ +V  +       PE+++ D
Sbjct: 398 VNTSKQTELLGELSFFSSGIDVPEINEEQSKVYNNALINWHHPEKDKAD 446


>gi|148833499 midline 1 [Homo sapiens]
          Length = 667

 Score =  126 bits (316), Expect = 4e-29
 Identities = 96/387 (24%), Positives = 179/387 (46%), Gaps = 42/387 (10%)

Query: 17  MDNLEKQLICPICLEMFSKPVVILPCQHNLCRKCANDVFQASNPLWQSRGSTTVSSGGRF 76
           M+ LE +L CPICLE+F  P+ +LPC H+LC  CA+ +  +     +S  S T      F
Sbjct: 1   METLESELTCPICLELFEDPL-LLPCAHSLCFNCAHRILVSHCATNESVESITA-----F 54

Query: 77  RCPSCRHEVVLDRHGVYGLQRNLLVENIIDIYKQES----SRPLHSKAEQHL-------- 124
           +CP+CRH + L + G+ GL+RN+ ++NIID +++ S    + P  ++ E+          
Sbjct: 55  QCPTCRHVITLSQRGLDGLKRNVTLQNIIDRFQKASVSGPNSPSETRRERAFDANTMTSA 114

Query: 125 ------MCEEHEEEKINIYCLSCEVPTCSLC--------KVFGAHKDCEVAPLPTIYKRQ 170
                  C++   +     C++CEV  C  C        K F  H+  E  P   I    
Sbjct: 115 EKVLCQFCDQDPAQDAVKTCVTCEVSYCDECLKATHPNKKPFTGHRLIEPIPDSHIRGLM 174

Query: 171 KKQDLTLLPRLECSGTNTTYCSLD--LPSSSDPPILA-SQNTKIIDSELSDGIAMLVAGN 227
             +       + C   +   C+L   +    D  + A S+    +   L   +  L+  N
Sbjct: 175 CLEHEDEKVNMYCVTDDQLICALCKLVGRHRDHQVAALSERYDKLKQNLESNLTNLIKRN 234

Query: 228 DRVQAVITQMEEVCQTIEDNSRRQKQLLNQRFESLCAVLEERKGELLQALAREQEEKLQR 287
             ++ ++ ++ + CQ +E N+ RQ+  L +  + L  ++++R+  +   +   +E K+ R
Sbjct: 235 TELETLLAKLIQTCQHVEVNASRQEAKLTEECDLLIEIIQQRRQIIGTKI---KEGKVMR 291

Query: 288 VRGLIRQYGD---HLEASSKLVESAIQSMEEPQMALYLQQAKELINKVGAMSKVELAGRP 344
           +R L +Q  +    +E S+ L+  A  S++E   A +LQ AK +  +V   +       P
Sbjct: 292 LRKLAQQIANCKQCIERSASLISQAEHSLKENDHARFLQTAKNITERVSMATASSQVLIP 351

Query: 345 EPGY-ESMEQFTVRVEHVAEMLRTIDF 370
           E    ++ + F +      ++L  +D+
Sbjct: 352 EINLNDTFDTFALDFSREKKLLECLDY 378


>gi|4557753 midline 1 [Homo sapiens]
          Length = 667

 Score =  126 bits (316), Expect = 4e-29
 Identities = 96/387 (24%), Positives = 179/387 (46%), Gaps = 42/387 (10%)

Query: 17  MDNLEKQLICPICLEMFSKPVVILPCQHNLCRKCANDVFQASNPLWQSRGSTTVSSGGRF 76
           M+ LE +L CPICLE+F  P+ +LPC H+LC  CA+ +  +     +S  S T      F
Sbjct: 1   METLESELTCPICLELFEDPL-LLPCAHSLCFNCAHRILVSHCATNESVESITA-----F 54

Query: 77  RCPSCRHEVVLDRHGVYGLQRNLLVENIIDIYKQES----SRPLHSKAEQHL-------- 124
           +CP+CRH + L + G+ GL+RN+ ++NIID +++ S    + P  ++ E+          
Sbjct: 55  QCPTCRHVITLSQRGLDGLKRNVTLQNIIDRFQKASVSGPNSPSETRRERAFDANTMTSA 114

Query: 125 ------MCEEHEEEKINIYCLSCEVPTCSLC--------KVFGAHKDCEVAPLPTIYKRQ 170
                  C++   +     C++CEV  C  C        K F  H+  E  P   I    
Sbjct: 115 EKVLCQFCDQDPAQDAVKTCVTCEVSYCDECLKATHPNKKPFTGHRLIEPIPDSHIRGLM 174

Query: 171 KKQDLTLLPRLECSGTNTTYCSLD--LPSSSDPPILA-SQNTKIIDSELSDGIAMLVAGN 227
             +       + C   +   C+L   +    D  + A S+    +   L   +  L+  N
Sbjct: 175 CLEHEDEKVNMYCVTDDQLICALCKLVGRHRDHQVAALSERYDKLKQNLESNLTNLIKRN 234

Query: 228 DRVQAVITQMEEVCQTIEDNSRRQKQLLNQRFESLCAVLEERKGELLQALAREQEEKLQR 287
             ++ ++ ++ + CQ +E N+ RQ+  L +  + L  ++++R+  +   +   +E K+ R
Sbjct: 235 TELETLLAKLIQTCQHVEVNASRQEAKLTEECDLLIEIIQQRRQIIGTKI---KEGKVMR 291

Query: 288 VRGLIRQYGD---HLEASSKLVESAIQSMEEPQMALYLQQAKELINKVGAMSKVELAGRP 344
           +R L +Q  +    +E S+ L+  A  S++E   A +LQ AK +  +V   +       P
Sbjct: 292 LRKLAQQIANCKQCIERSASLISQAEHSLKENDHARFLQTAKNITERVSMATASSQVLIP 351

Query: 345 EPGY-ESMEQFTVRVEHVAEMLRTIDF 370
           E    ++ + F +      ++L  +D+
Sbjct: 352 EINLNDTFDTFALDFSREKKLLECLDY 378


>gi|15451852 midline 1 [Homo sapiens]
          Length = 667

 Score =  126 bits (316), Expect = 4e-29
 Identities = 96/387 (24%), Positives = 179/387 (46%), Gaps = 42/387 (10%)

Query: 17  MDNLEKQLICPICLEMFSKPVVILPCQHNLCRKCANDVFQASNPLWQSRGSTTVSSGGRF 76
           M+ LE +L CPICLE+F  P+ +LPC H+LC  CA+ +  +     +S  S T      F
Sbjct: 1   METLESELTCPICLELFEDPL-LLPCAHSLCFNCAHRILVSHCATNESVESITA-----F 54

Query: 77  RCPSCRHEVVLDRHGVYGLQRNLLVENIIDIYKQES----SRPLHSKAEQHL-------- 124
           +CP+CRH + L + G+ GL+RN+ ++NIID +++ S    + P  ++ E+          
Sbjct: 55  QCPTCRHVITLSQRGLDGLKRNVTLQNIIDRFQKASVSGPNSPSETRRERAFDANTMTSA 114

Query: 125 ------MCEEHEEEKINIYCLSCEVPTCSLC--------KVFGAHKDCEVAPLPTIYKRQ 170
                  C++   +     C++CEV  C  C        K F  H+  E  P   I    
Sbjct: 115 EKVLCQFCDQDPAQDAVKTCVTCEVSYCDECLKATHPNKKPFTGHRLIEPIPDSHIRGLM 174

Query: 171 KKQDLTLLPRLECSGTNTTYCSLD--LPSSSDPPILA-SQNTKIIDSELSDGIAMLVAGN 227
             +       + C   +   C+L   +    D  + A S+    +   L   +  L+  N
Sbjct: 175 CLEHEDEKVNMYCVTDDQLICALCKLVGRHRDHQVAALSERYDKLKQNLESNLTNLIKRN 234

Query: 228 DRVQAVITQMEEVCQTIEDNSRRQKQLLNQRFESLCAVLEERKGELLQALAREQEEKLQR 287
             ++ ++ ++ + CQ +E N+ RQ+  L +  + L  ++++R+  +   +   +E K+ R
Sbjct: 235 TELETLLAKLIQTCQHVEVNASRQEAKLTEECDLLIEIIQQRRQIIGTKI---KEGKVMR 291

Query: 288 VRGLIRQYGD---HLEASSKLVESAIQSMEEPQMALYLQQAKELINKVGAMSKVELAGRP 344
           +R L +Q  +    +E S+ L+  A  S++E   A +LQ AK +  +V   +       P
Sbjct: 292 LRKLAQQIANCKQCIERSASLISQAEHSLKENDHARFLQTAKNITERVSMATASSQVLIP 351

Query: 345 EPGY-ESMEQFTVRVEHVAEMLRTIDF 370
           E    ++ + F +      ++L  +D+
Sbjct: 352 EINLNDTFDTFALDFSREKKLLECLDY 378


>gi|223890259 midline 2 isoform 2 [Homo sapiens]
          Length = 705

 Score =  125 bits (314), Expect = 7e-29
 Identities = 97/390 (24%), Positives = 178/390 (45%), Gaps = 48/390 (12%)

Query: 17  MDNLEKQLICPICLEMFSKPVVILPCQHNLCRKCANDVFQASNPLWQSRGSTTVSSGGRF 76
           M+ LE +L CPICLE+F  P+ +LPC H+LC  CA+ +  +S    +S    T      F
Sbjct: 21  METLESELTCPICLELFEDPL-LLPCAHSLCFSCAHRILVSSCSSGESIEPITA-----F 74

Query: 77  RCPSCRHEVVLDRHGVYGLQRNLLVENIIDIYKQES----SRPLHSKAEQHL-------- 124
           +CP+CR+ + L+  G+ GL+RN+ ++NIID +++ S    + P  S+ E+          
Sbjct: 75  QCPTCRYVISLNHRGLDGLKRNVTLQNIIDRFQKASVSGPNSPSESRRERTYRPTTAMSS 134

Query: 125 ------MCEEHEEEKINIYCLSCEVPTCSLC--------KVFGAHKDCEVAPLPTIYKRQ 170
                  CE+         C++CEV  C  C        K F +H+   V P+P  + R 
Sbjct: 135 ERIACQFCEQDPPRDAVKTCITCEVSYCDRCLRATHPNKKPFTSHR--LVEPVPDTHLR- 191

Query: 171 KKQDLTLLP------RLECSGTNTTYCSL-DLPSSSDPPILASQNTKI--IDSELSDGIA 221
               +T L        + C   +   C+L  L        +AS N +   +   L   + 
Sbjct: 192 ---GITCLDHENEKVNMYCVSDDQLICALCKLVGRHRDHQVASLNDRFEKLKQTLEMNLT 248

Query: 222 MLVAGNDRVQAVITQMEEVCQTIEDNSRRQKQLLNQRFESLCAVLEERKGELLQALAREQ 281
            LV  N  ++  + ++ ++CQ +E N+   +  L +  + L  ++++RK  +   +   +
Sbjct: 249 NLVKRNSELENQMAKLIQICQQVEVNTAMHEAKLMEECDELVEIIQQRKQMIAVKIKETK 308

Query: 282 EEKLQRVRGLIRQYGDHLEASSKLVESAIQSMEEPQMALYLQQAKELINKVGAMSKVELA 341
             KL+++   +      LE S+ L+  A   ++E   A +LQ AK +  +V   +     
Sbjct: 309 VMKLRKLAQQVANCRQCLERSTVLINQAEHILKENDQARFLQSAKNIAERVAMATASSQV 368

Query: 342 GRPEPGY-ESMEQFTVRVEHVAEMLRTIDF 370
             P+  + ++ E F +      ++L  +D+
Sbjct: 369 LIPDINFNDAFENFALDFSREKKLLEGLDY 398


>gi|223890257 midline 2 isoform 1 [Homo sapiens]
          Length = 735

 Score =  125 bits (314), Expect = 7e-29
 Identities = 97/390 (24%), Positives = 178/390 (45%), Gaps = 48/390 (12%)

Query: 17  MDNLEKQLICPICLEMFSKPVVILPCQHNLCRKCANDVFQASNPLWQSRGSTTVSSGGRF 76
           M+ LE +L CPICLE+F  P+ +LPC H+LC  CA+ +  +S    +S    T      F
Sbjct: 21  METLESELTCPICLELFEDPL-LLPCAHSLCFSCAHRILVSSCSSGESIEPITA-----F 74

Query: 77  RCPSCRHEVVLDRHGVYGLQRNLLVENIIDIYKQES----SRPLHSKAEQHL-------- 124
           +CP+CR+ + L+  G+ GL+RN+ ++NIID +++ S    + P  S+ E+          
Sbjct: 75  QCPTCRYVISLNHRGLDGLKRNVTLQNIIDRFQKASVSGPNSPSESRRERTYRPTTAMSS 134

Query: 125 ------MCEEHEEEKINIYCLSCEVPTCSLC--------KVFGAHKDCEVAPLPTIYKRQ 170
                  CE+         C++CEV  C  C        K F +H+   V P+P  + R 
Sbjct: 135 ERIACQFCEQDPPRDAVKTCITCEVSYCDRCLRATHPNKKPFTSHR--LVEPVPDTHLR- 191

Query: 171 KKQDLTLLP------RLECSGTNTTYCSL-DLPSSSDPPILASQNTKI--IDSELSDGIA 221
               +T L        + C   +   C+L  L        +AS N +   +   L   + 
Sbjct: 192 ---GITCLDHENEKVNMYCVSDDQLICALCKLVGRHRDHQVASLNDRFEKLKQTLEMNLT 248

Query: 222 MLVAGNDRVQAVITQMEEVCQTIEDNSRRQKQLLNQRFESLCAVLEERKGELLQALAREQ 281
            LV  N  ++  + ++ ++CQ +E N+   +  L +  + L  ++++RK  +   +   +
Sbjct: 249 NLVKRNSELENQMAKLIQICQQVEVNTAMHEAKLMEECDELVEIIQQRKQMIAVKIKETK 308

Query: 282 EEKLQRVRGLIRQYGDHLEASSKLVESAIQSMEEPQMALYLQQAKELINKVGAMSKVELA 341
             KL+++   +      LE S+ L+  A   ++E   A +LQ AK +  +V   +     
Sbjct: 309 VMKLRKLAQQVANCRQCLERSTVLINQAEHILKENDQARFLQSAKNIAERVAMATASSQV 368

Query: 342 GRPEPGY-ESMEQFTVRVEHVAEMLRTIDF 370
             P+  + ++ E F +      ++L  +D+
Sbjct: 369 LIPDINFNDAFENFALDFSREKKLLEGLDY 398


>gi|47174859 tripartite motif-containing 46 [Homo sapiens]
          Length = 759

 Score =  124 bits (312), Expect = 1e-28
 Identities = 109/403 (27%), Positives = 183/403 (45%), Gaps = 72/403 (17%)

Query: 3   FTVGFKPLLGDAHSMDNLEKQLICPICLEMFSKPVVILPCQHNLCRKCANDVF------- 55
           FT     L+  + SM N+EK+L+CP+C EM+ +P+V LPC HN+C+ CA +V        
Sbjct: 10  FTSIMDALVRISTSMKNMEKELLCPVCQEMYKQPLV-LPCTHNVCQACAREVLGQQGYIG 68

Query: 56  -----------QASNPLWQS------------RGSTTVSSG-----GR-----------F 76
                       AS P  +S            R    + SG     GR           F
Sbjct: 69  HGGDPSSEPTSPASTPSTRSPRLSRRTLPKPDRLDRLLKSGFGTYPGRKRGALHPQVIMF 128

Query: 77  RCPSCRHEVVLDRHGVYGLQRNLLVENIIDIYKQESSRPLHSKAEQHLMCEEHEEEKINI 136
            CP+C+ +V L   G+ GL RNL +E +++ Y+Q  S          ++C+  +   +  
Sbjct: 129 PCPACQGDVELGERGLAGLFRNLTLERVVERYRQSVS------VGGAILCQLCKPPPLEA 182

Query: 137 Y--CLSCEVPTCSLC-KVF---GAHKDCEVAPLPTIYKRQK-------KQDLTLLPRLEC 183
              C  C    C+ C K+F   G  K      LPT+  R K       K+++T   +  C
Sbjct: 183 TKGCTECRATFCNECFKLFHPWGTQKAQHEPTLPTLSFRPKGLMCPDHKEEVTHYCKT-C 241

Query: 184 SGTNTTYCSLDLPSSSDP--PILASQNTKIIDSELSDGIAMLVAGNDRVQAVITQMEEVC 241
                  C +    S     P+L++     +  +L+  +  ++   D VQ  I ++EE  
Sbjct: 242 QRLVCQLCRVRRTHSGHKITPVLSAYQA--LKDKLTKSLTYILGNQDTVQTQICELEEAV 299

Query: 242 QTIEDNSRRQKQLLNQRFESLCAVLEERKGELLQALAREQEEKLQRVRGLIRQYGDHLEA 301
           +  E + ++ K+ ++Q    L AVLEE++  LLQA+   Q+E+L R+   I+++   L+ 
Sbjct: 300 RHTEVSGQQAKEEVSQLVRGLGAVLEEKRASLLQAIEECQQERLARLSAQIQEHRSLLDG 359

Query: 302 SSKLVESAIQSMEEPQMALYLQQAKELINKVGAMSKVELAGRP 344
           S  LV  A + ++E     ++Q AK+L N++   ++     RP
Sbjct: 360 SG-LVGYAQEVLKETDQPCFVQAAKQLHNRIARATEALQTFRP 401


>gi|27436877 tripartite motif-containing 59 [Homo sapiens]
          Length = 403

 Score = 88.2 bits (217), Expect = 1e-17
 Identities = 51/165 (30%), Positives = 75/165 (45%), Gaps = 13/165 (7%)

Query: 17  MDNLEKQLICPICLEMFSKPVVILPCQHNLCRKCANDVFQASNPLWQSRGSTTVSSGGRF 76
           M N E++L CPIC  +F  P V LPC H  CR C  ++ QAS   +  R           
Sbjct: 1   MHNFEEELTCPICYSIFEDPRV-LPCSHTFCRNCLENILQASGNFYIWRPLRIP-----L 54

Query: 77  RCPSCRHEVVLDRHGVYGLQRNLLVENIIDIYKQESSRPLHSKAEQHLMCEEHEEEKINI 136
           +CP+CR    +   G+  L  N  +  II+ Y+QE    +       + C EH  + +N+
Sbjct: 55  KCPNCRSITEIAPTGIESLPVNFALRAIIEKYQQEDHPDI-------VTCPEHYRQPLNV 107

Query: 137 YCLSCEVPTCSLCKVFGAHKDCEVAPLPTIYKRQKKQDLTLLPRL 181
           YCL  +   C  C   G H    +  L + Y ++K     LL +L
Sbjct: 108 YCLLDKKLVCGHCLTIGQHHGHPIDDLQSAYLKEKDTPQKLLEQL 152


>gi|32454739 tripartite motif-containing 3 [Homo sapiens]
          Length = 744

 Score = 86.7 bits (213), Expect = 3e-17
 Identities = 81/329 (24%), Positives = 134/329 (40%), Gaps = 70/329 (21%)

Query: 20  LEKQ-LICPICLEMFSKPVVILPCQHNLCRKCANDVFQASNPLWQSRGSTTVSSGGRFRC 78
           ++KQ L+C ICL+ +  P V LPC H  C +C  +   A         S T+S      C
Sbjct: 15  MDKQFLVCSICLDRYQCPKV-LPCLHTFCERCLQNYIPAQ--------SLTLS------C 59

Query: 79  PSCRHEVVLDRHGVYGLQRNLLVENIIDIYKQ--------ESSRPLHSKAEQHLMCEEHE 130
           P CR   +L   GV  LQ N  + ++++  +Q        E   PL   A + L C  HE
Sbjct: 60  PVCRQTSILPEQGVSALQNNFFISSLMEAMQQAPDGAHDPEDPHPLSVVAGRPLSCPNHE 119

Query: 131 EEKINIYCLSCEVPTCSLCKVFGAHKDCEVAPLPTIYKRQKKQDLTLLPRLECSGTNTTY 190
            + +  YC +CE   C  C+  G H++     L  + ++ K     L  +LE        
Sbjct: 120 GKTMEFYCEACETAMCGECRA-GEHREHGTVLLRDVVEQHK---AALQRQLEAVRGR--- 172

Query: 191 CSLDLPSSSDPPILASQNTKIIDSELSDGIAMLVAGNDRVQAVITQMEEVCQTIEDNSRR 250
               LP                  +LS  IA LV G             + Q +++    
Sbjct: 173 ----LP------------------QLSAAIA-LVGG-------------ISQQLQERKAE 196

Query: 251 QKQLLNQRFESLCAVLEERKGEL---LQALAREQEEKLQRVRGLIRQYGDHLEASSKLVE 307
               ++  FE L   L++RK  L   L+ +   +++ LQ     +RQ  +H+ +S    E
Sbjct: 197 ALAQISAAFEDLEQALQQRKQALVSDLETICGAKQKVLQSQLDTLRQGQEHIGSSCSFAE 256

Query: 308 SAIQSMEEPQMALYLQQAKELINKVGAMS 336
            A++    P++ L  +  +E +  + A +
Sbjct: 257 QALRLGSAPEVLLVRKHMRERLAALAAQA 285


>gi|32454737 tripartite motif-containing 3 [Homo sapiens]
          Length = 744

 Score = 86.7 bits (213), Expect = 3e-17
 Identities = 81/329 (24%), Positives = 134/329 (40%), Gaps = 70/329 (21%)

Query: 20  LEKQ-LICPICLEMFSKPVVILPCQHNLCRKCANDVFQASNPLWQSRGSTTVSSGGRFRC 78
           ++KQ L+C ICL+ +  P V LPC H  C +C  +   A         S T+S      C
Sbjct: 15  MDKQFLVCSICLDRYQCPKV-LPCLHTFCERCLQNYIPAQ--------SLTLS------C 59

Query: 79  PSCRHEVVLDRHGVYGLQRNLLVENIIDIYKQ--------ESSRPLHSKAEQHLMCEEHE 130
           P CR   +L   GV  LQ N  + ++++  +Q        E   PL   A + L C  HE
Sbjct: 60  PVCRQTSILPEQGVSALQNNFFISSLMEAMQQAPDGAHDPEDPHPLSVVAGRPLSCPNHE 119

Query: 131 EEKINIYCLSCEVPTCSLCKVFGAHKDCEVAPLPTIYKRQKKQDLTLLPRLECSGTNTTY 190
            + +  YC +CE   C  C+  G H++     L  + ++ K     L  +LE        
Sbjct: 120 GKTMEFYCEACETAMCGECRA-GEHREHGTVLLRDVVEQHK---AALQRQLEAVRGR--- 172

Query: 191 CSLDLPSSSDPPILASQNTKIIDSELSDGIAMLVAGNDRVQAVITQMEEVCQTIEDNSRR 250
               LP                  +LS  IA LV G             + Q +++    
Sbjct: 173 ----LP------------------QLSAAIA-LVGG-------------ISQQLQERKAE 196

Query: 251 QKQLLNQRFESLCAVLEERKGEL---LQALAREQEEKLQRVRGLIRQYGDHLEASSKLVE 307
               ++  FE L   L++RK  L   L+ +   +++ LQ     +RQ  +H+ +S    E
Sbjct: 197 ALAQISAAFEDLEQALQQRKQALVSDLETICGAKQKVLQSQLDTLRQGQEHIGSSCSFAE 256

Query: 308 SAIQSMEEPQMALYLQQAKELINKVGAMS 336
            A++    P++ L  +  +E +  + A +
Sbjct: 257 QALRLGSAPEVLLVRKHMRERLAALAAQA 285


>gi|55953112 ret finger protein 2 isoform 2 [Homo sapiens]
          Length = 410

 Score = 85.5 bits (210), Expect = 8e-17
 Identities = 76/347 (21%), Positives = 140/347 (40%), Gaps = 75/347 (21%)

Query: 17  MDNLEKQLICPICLEMFSKPVVILPCQHNLCRKCANDVFQAS--NPLWQSRGSTTVSSGG 74
           M+ LE+ L CPIC  +F  P V LPC HN C+KC   + + S  N LW+           
Sbjct: 4   MELLEEDLTCPICCSLFDDPRV-LPCSHNFCKKCLEGILEGSVRNSLWRP---------A 53

Query: 75  RFRCPSCRHEVVLDRHGVYGLQRNLLVENIIDIYKQESSRPLHSKAEQHLMCEEHEEEKI 134
            F+CP+CR E      G+  LQ N  ++ I++ Y +    P      +  +C+ H  + +
Sbjct: 54  PFKCPTCRKET--SATGINSLQVNYSLKGIVEKYNKIKISP------KMPVCKGHLGQPL 105

Query: 135 NIYCLSCEVPTCSLCKVFGAHKDCEVAPLPTIYKRQKKQDLTLLPRLECSGTNTTYCSLD 194
           NI+CL+     C +C   G H                              T   +CS++
Sbjct: 106 NIFCLTDMQLICGICATRGEH------------------------------TKHVFCSIE 135

Query: 195 LPSSSDPPILASQNTKIIDSELSDGIAMLVAGNDRVQAVITQMEEVCQTIEDNSRRQKQL 254
              + +     S           D ++       R+  + T   +  Q +  +S + K+ 
Sbjct: 136 DAYAQERDAFESLFQSFETWRRGDALS-------RLDTLETSKRKSLQLLTKDSDKVKEF 188

Query: 255 LNQRFESLCAVLEERKGELLQ-------ALAREQEEKLQRVRGLIRQYGDHLEASSKLVE 307
               FE L   L+++K E+L        A+ +  + ++ ++  ++++     +  +  + 
Sbjct: 189 ----FEKLQHTLDQKKNEILSDFETMKLAVMQAYDPEINKLNTILQE-----QRMAFNIA 239

Query: 308 SAIQSMEEPQMALYLQQAKELINKVGAMSKVELAGRPEPGYESMEQF 354
            A + + EP   ++LQQ +E   K+  + +  L     P    M+ F
Sbjct: 240 EAFKDVSEP--IVFLQQMQEFREKIKVIKETPLPPSNLPASPLMKNF 284


>gi|47132524 ret finger protein 2 isoform 1 [Homo sapiens]
          Length = 407

 Score = 85.5 bits (210), Expect = 8e-17
 Identities = 76/347 (21%), Positives = 140/347 (40%), Gaps = 75/347 (21%)

Query: 17  MDNLEKQLICPICLEMFSKPVVILPCQHNLCRKCANDVFQAS--NPLWQSRGSTTVSSGG 74
           M+ LE+ L CPIC  +F  P V LPC HN C+KC   + + S  N LW+           
Sbjct: 1   MELLEEDLTCPICCSLFDDPRV-LPCSHNFCKKCLEGILEGSVRNSLWRP---------A 50

Query: 75  RFRCPSCRHEVVLDRHGVYGLQRNLLVENIIDIYKQESSRPLHSKAEQHLMCEEHEEEKI 134
            F+CP+CR E      G+  LQ N  ++ I++ Y +    P      +  +C+ H  + +
Sbjct: 51  PFKCPTCRKET--SATGINSLQVNYSLKGIVEKYNKIKISP------KMPVCKGHLGQPL 102

Query: 135 NIYCLSCEVPTCSLCKVFGAHKDCEVAPLPTIYKRQKKQDLTLLPRLECSGTNTTYCSLD 194
           NI+CL+     C +C   G H                              T   +CS++
Sbjct: 103 NIFCLTDMQLICGICATRGEH------------------------------TKHVFCSIE 132

Query: 195 LPSSSDPPILASQNTKIIDSELSDGIAMLVAGNDRVQAVITQMEEVCQTIEDNSRRQKQL 254
              + +     S           D ++       R+  + T   +  Q +  +S + K+ 
Sbjct: 133 DAYAQERDAFESLFQSFETWRRGDALS-------RLDTLETSKRKSLQLLTKDSDKVKEF 185

Query: 255 LNQRFESLCAVLEERKGELLQ-------ALAREQEEKLQRVRGLIRQYGDHLEASSKLVE 307
               FE L   L+++K E+L        A+ +  + ++ ++  ++++     +  +  + 
Sbjct: 186 ----FEKLQHTLDQKKNEILSDFETMKLAVMQAYDPEINKLNTILQE-----QRMAFNIA 236

Query: 308 SAIQSMEEPQMALYLQQAKELINKVGAMSKVELAGRPEPGYESMEQF 354
            A + + EP   ++LQQ +E   K+  + +  L     P    M+ F
Sbjct: 237 EAFKDVSEP--IVFLQQMQEFREKIKVIKETPLPPSNLPASPLMKNF 281


>gi|16445412 ret finger protein 2 isoform 1 [Homo sapiens]
          Length = 407

 Score = 85.5 bits (210), Expect = 8e-17
 Identities = 76/347 (21%), Positives = 140/347 (40%), Gaps = 75/347 (21%)

Query: 17  MDNLEKQLICPICLEMFSKPVVILPCQHNLCRKCANDVFQAS--NPLWQSRGSTTVSSGG 74
           M+ LE+ L CPIC  +F  P V LPC HN C+KC   + + S  N LW+           
Sbjct: 1   MELLEEDLTCPICCSLFDDPRV-LPCSHNFCKKCLEGILEGSVRNSLWRP---------A 50

Query: 75  RFRCPSCRHEVVLDRHGVYGLQRNLLVENIIDIYKQESSRPLHSKAEQHLMCEEHEEEKI 134
            F+CP+CR E      G+  LQ N  ++ I++ Y +    P      +  +C+ H  + +
Sbjct: 51  PFKCPTCRKET--SATGINSLQVNYSLKGIVEKYNKIKISP------KMPVCKGHLGQPL 102

Query: 135 NIYCLSCEVPTCSLCKVFGAHKDCEVAPLPTIYKRQKKQDLTLLPRLECSGTNTTYCSLD 194
           NI+CL+     C +C   G H                              T   +CS++
Sbjct: 103 NIFCLTDMQLICGICATRGEH------------------------------TKHVFCSIE 132

Query: 195 LPSSSDPPILASQNTKIIDSELSDGIAMLVAGNDRVQAVITQMEEVCQTIEDNSRRQKQL 254
              + +     S           D ++       R+  + T   +  Q +  +S + K+ 
Sbjct: 133 DAYAQERDAFESLFQSFETWRRGDALS-------RLDTLETSKRKSLQLLTKDSDKVKEF 185

Query: 255 LNQRFESLCAVLEERKGELLQ-------ALAREQEEKLQRVRGLIRQYGDHLEASSKLVE 307
               FE L   L+++K E+L        A+ +  + ++ ++  ++++     +  +  + 
Sbjct: 186 ----FEKLQHTLDQKKNEILSDFETMKLAVMQAYDPEINKLNTILQE-----QRMAFNIA 236

Query: 308 SAIQSMEEPQMALYLQQAKELINKVGAMSKVELAGRPEPGYESMEQF 354
            A + + EP   ++LQQ +E   K+  + +  L     P    M+ F
Sbjct: 237 EAFKDVSEP--IVFLQQMQEFREKIKVIKETPLPPSNLPASPLMKNF 281


>gi|47132521 ret finger protein 2 isoform 1 [Homo sapiens]
          Length = 407

 Score = 85.5 bits (210), Expect = 8e-17
 Identities = 76/347 (21%), Positives = 140/347 (40%), Gaps = 75/347 (21%)

Query: 17  MDNLEKQLICPICLEMFSKPVVILPCQHNLCRKCANDVFQAS--NPLWQSRGSTTVSSGG 74
           M+ LE+ L CPIC  +F  P V LPC HN C+KC   + + S  N LW+           
Sbjct: 1   MELLEEDLTCPICCSLFDDPRV-LPCSHNFCKKCLEGILEGSVRNSLWRP---------A 50

Query: 75  RFRCPSCRHEVVLDRHGVYGLQRNLLVENIIDIYKQESSRPLHSKAEQHLMCEEHEEEKI 134
            F+CP+CR E      G+  LQ N  ++ I++ Y +    P      +  +C+ H  + +
Sbjct: 51  PFKCPTCRKET--SATGINSLQVNYSLKGIVEKYNKIKISP------KMPVCKGHLGQPL 102

Query: 135 NIYCLSCEVPTCSLCKVFGAHKDCEVAPLPTIYKRQKKQDLTLLPRLECSGTNTTYCSLD 194
           NI+CL+     C +C   G H                              T   +CS++
Sbjct: 103 NIFCLTDMQLICGICATRGEH------------------------------TKHVFCSIE 132

Query: 195 LPSSSDPPILASQNTKIIDSELSDGIAMLVAGNDRVQAVITQMEEVCQTIEDNSRRQKQL 254
              + +     S           D ++       R+  + T   +  Q +  +S + K+ 
Sbjct: 133 DAYAQERDAFESLFQSFETWRRGDALS-------RLDTLETSKRKSLQLLTKDSDKVKEF 185

Query: 255 LNQRFESLCAVLEERKGELLQ-------ALAREQEEKLQRVRGLIRQYGDHLEASSKLVE 307
               FE L   L+++K E+L        A+ +  + ++ ++  ++++     +  +  + 
Sbjct: 186 ----FEKLQHTLDQKKNEILSDFETMKLAVMQAYDPEINKLNTILQE-----QRMAFNIA 236

Query: 308 SAIQSMEEPQMALYLQQAKELINKVGAMSKVELAGRPEPGYESMEQF 354
            A + + EP   ++LQQ +E   K+  + +  L     P    M+ F
Sbjct: 237 EAFKDVSEP--IVFLQQMQEFREKIKVIKETPLPPSNLPASPLMKNF 281


>gi|194248081 tripartite motif-containing 2 isoform 2 [Homo sapiens]
          Length = 744

 Score = 77.8 bits (190), Expect = 2e-14
 Identities = 52/163 (31%), Positives = 73/163 (44%), Gaps = 27/163 (16%)

Query: 20  LEKQ-LICPICLEMFSKPVVILPCQHNLCRKCANDVFQASNPLWQSRGSTTVSSGGRFRC 78
           ++KQ LIC ICLE +  P V LPC H  C +C  +   A         S T+S      C
Sbjct: 16  IDKQFLICSICLERYKNPKV-LPCLHTFCERCLQNYIPAH--------SLTLS------C 60

Query: 79  PSCRHEVVLDRHGVYGLQRNLLVENIIDIYKQ------ESSRPLHS----KAEQHLMCEE 128
           P CR   +L   GV  LQ N  + N++D+ ++      E S  L +     A + L C  
Sbjct: 61  PVCRQTSILPEKGVAALQNNFFITNLMDVLQRTPGSNAEESSILETVTAVAAGKPLSCPN 120

Query: 129 HEEEKINIYCLSCEVPTCSLCKVFGAHKDCEVAPLPTIYKRQK 171
           H+   +  YC SCE   C  C   G H +    PL  + ++ K
Sbjct: 121 HDGNVMEFYCQSCETAMCREC-TEGEHAEHPTVPLKDVVEQHK 162


>gi|194248079 tripartite motif-containing 2 isoform 1 [Homo sapiens]
          Length = 771

 Score = 77.8 bits (190), Expect = 2e-14
 Identities = 52/163 (31%), Positives = 73/163 (44%), Gaps = 27/163 (16%)

Query: 20  LEKQ-LICPICLEMFSKPVVILPCQHNLCRKCANDVFQASNPLWQSRGSTTVSSGGRFRC 78
           ++KQ LIC ICLE +  P V LPC H  C +C  +   A         S T+S      C
Sbjct: 43  IDKQFLICSICLERYKNPKV-LPCLHTFCERCLQNYIPAH--------SLTLS------C 87

Query: 79  PSCRHEVVLDRHGVYGLQRNLLVENIIDIYKQ------ESSRPLHS----KAEQHLMCEE 128
           P CR   +L   GV  LQ N  + N++D+ ++      E S  L +     A + L C  
Sbjct: 88  PVCRQTSILPEKGVAALQNNFFITNLMDVLQRTPGSNAEESSILETVTAVAAGKPLSCPN 147

Query: 129 HEEEKINIYCLSCEVPTCSLCKVFGAHKDCEVAPLPTIYKRQK 171
           H+   +  YC SCE   C  C   G H +    PL  + ++ K
Sbjct: 148 HDGNVMEFYCQSCETAMCREC-TEGEHAEHPTVPLKDVVEQHK 189


>gi|134288906 tripartite motif-containing 67 [Homo sapiens]
          Length = 783

 Score = 77.0 bits (188), Expect = 3e-14
 Identities = 61/253 (24%), Positives = 104/253 (41%), Gaps = 42/253 (16%)

Query: 118 SKAEQHLMCEEHEEEKINIYCLSCEVPTCSLCKVFGAHKDCEVAPLPTIYKRQKKQDLTL 177
           S A +   C EHE E  ++YC+SC  P C LC   G H   EV PL  ++K+ K Q    
Sbjct: 295 STARKFPTCPEHEMENYSMYCVSCRTPVCYLCLEEGRHAKHEVKPLGAMWKQHKAQ---- 350

Query: 178 LPRLECSGTNTTYCSLDLPSSSDPPILASQNTKIIDSELSDGIAMLVAGNDRVQAVITQM 237
                                       SQ    +  +  +    LV           Q+
Sbjct: 351 ---------------------------LSQALNGVSDKAKEAKEFLV-----------QL 372

Query: 238 EEVCQTIEDNSRRQKQLLNQRFESLCAVLEERKGELLQALAREQEEKLQRVRGLIRQYGD 297
           + + Q I++N    +  L  + ++L   L  +K +LL  + +E+E KL+ V   I     
Sbjct: 373 KNILQQIQENGLDYEACLVAQCDALVDALTRQKAKLLTKVTKEREHKLKMVWDQINHCTL 432

Query: 298 HLEASSKLVESAIQSMEEPQMALYLQQAKELINKVGAMSKVELAGRPEPGYESMEQFTVR 357
            L  S+ L+E  ++ ++E   + +LQ +  LI +V    +  + G  EP   +    T+ 
Sbjct: 433 KLRQSTGLMEYCLEVIKENDPSGFLQISDALIKRVQVSQEQWVKGALEPKVSAEFDLTLD 492

Query: 358 VEHVAEMLRTIDF 370
            E + + +  +DF
Sbjct: 493 SEPLLQAIHQLDF 505



 Score = 48.9 bits (115), Expect = 8e-06
 Identities = 31/110 (28%), Positives = 45/110 (40%), Gaps = 12/110 (10%)

Query: 67  STTVSSGGRFRCPSCRHEVVLDRHGVYGLQRNLLVENIIDIYKQESSRPLHSKAEQHL-- 124
           S+  SS     CP C     LD  G+ G QRN L+E I+  Y+Q       + A   +  
Sbjct: 148 SSLSSSSSSITCPQCHRSASLDHRGLRGFQRNRLLEAIVQRYQQGRGAVPGTSAAAAVAI 207

Query: 125 --MCEEHEEEKINIYCLSCEVPTCSLCKV--------FGAHKDCEVAPLP 164
             +C+    E     C  C+V  CS C++        F  H+  +  P P
Sbjct: 208 CQLCDRTPPEPAATLCEQCDVLYCSACQLKCHPSRGPFAKHRLVQPPPPP 257



 Score = 44.7 bits (104), Expect = 2e-04
 Identities = 22/56 (39%), Positives = 31/56 (55%), Gaps = 9/56 (16%)

Query: 20 LEKQLICPICLEMFSKPVVILPCQHNLCRKCANDVF--------QASNPLWQSRGS 67
          +E++L CP+C  +F +P+ ILPC HN+C  CA  +             PL  SRGS
Sbjct: 1  MEEELKCPVCGSLFREPI-ILPCSHNVCLPCARTIAVQTPDGEQHLPQPLLLSRGS 55


>gi|55741632 fibronectin type III and SPRY domain containing 2 [Homo
           sapiens]
          Length = 749

 Score = 76.3 bits (186), Expect = 5e-14
 Identities = 64/275 (23%), Positives = 122/275 (44%), Gaps = 57/275 (20%)

Query: 110 QESSRPLHSKAEQHLMC-----EEHEEEKINIYCLSCEVPTCSLCKVFGAHKDCEVAPLP 164
           +E+ R  H +A +   C     EE EEE  +++C++C+ P  +  KVF  HK+ EV PL 
Sbjct: 147 REAYRYTHGRASEEYECYVIPEEEDEEEAADVFCVTCKTPIRAFQKVFDEHKEHEVIPLN 206

Query: 165 TIYKRQKKQDLTLLPRLECSGTNTTYCSLDLPSSSDPPILASQNTKIIDSELSDGIAMLV 224
              +  K +    + +LE                           +II+ E         
Sbjct: 207 EALESAKDEIHKNMYKLE--------------------------KQIIEME--------- 231

Query: 225 AGNDRVQAVITQMEEVCQTIEDNSRRQKQLLNQRFESLCAVLEERKGELLQALAREQEEK 284
                       +EEV  T+E+N  +Q+Q     +  +   L ++  E +QAL  +++EK
Sbjct: 232 -------NFANHLEEVFITVEENFGKQEQNFESHYNEILETLAQKYEEKIQALGEKKKEK 284

Query: 285 LQRVRGLIRQYGDHLEASSKLVESAIQSMEEPQMALYLQQAKELINKVGAMSK----VEL 340
           L+ + G +   G++L+   +L+E+ I+ M   +   +++ A  + +++G   K    VE+
Sbjct: 285 LEALYGQLVSCGENLDTCKELMET-IEEMCHEEKVDFIKDAVAMADRLGKFLKTKTDVEI 343

Query: 341 AGRPEPGYESMEQFTVRVEHVAEMLRTIDFQPGAS 375
           + +PE      E  T+    V +++ +I+  P  S
Sbjct: 344 SAQPE-----FEDQTLDFSDVEQLMGSINTIPAPS 373


>gi|14670266 tripartite motif protein TRIM4 isoform alpha [Homo
           sapiens]
          Length = 500

 Score = 67.0 bits (162), Expect = 3e-11
 Identities = 67/314 (21%), Positives = 125/314 (39%), Gaps = 43/314 (13%)

Query: 18  DNLEKQLICPICLEMFSKPVVILPCQHNLCRKCANDVFQASNPLWQSRGSTTVSSGGRFR 77
           ++++++L CPICL+ F  PV I  C HN CR C +                    GG F 
Sbjct: 4   EDIQEELTCPICLDYFQDPVSI-ECGHNFCRGCLH--------------RNWAPGGGPFP 48

Query: 78  CPSCRHEVVLDRHGVYGLQRNLLVENIIDIYKQESSRPLHSKAEQHLMCEEHEEEKINIY 137
           CP CRH           L+ N  +  + +  ++    P+        +C  H  E + ++
Sbjct: 49  CPECRHP-----SAPAALRPNWALARLTEKTQRRRLGPVPPG-----LCGRH-WEPLRLF 97

Query: 138 CLSCEVPTCSLCKVFGAHKDCEVAPLPTIYKRQKKQDLTLLPRLECSGTNTTYCSLDLPS 197
           C   + P C +C+    H+   +AP+   ++  +  +      +           L L  
Sbjct: 98  CEDDQRPVCLVCRESQEHQTHAMAPIDEAFESYRTGNFD----IHVDEWKRRLIRLLLYH 153

Query: 198 SSDPPILASQNTKIIDSELSDGIAMLVAGNDRVQAVITQMEEVCQTIEDNSRRQKQLLNQ 257
           S        Q  K++ S+ +     LVA   +V  +     +     +D  + Q+  ++ 
Sbjct: 154 S-------KQEEKLLKSQRN-----LVAKMKKVMHLQDVEVKNATQWKDKIKSQRMRIST 201

Query: 258 RFESLCAVLEERKGELLQALAREQEEKLQRVRGLIRQYGDHLEASSKLVESAIQSMEEPQ 317
            F  L   L E +   LQ L +E+EE  +++     +    + +  KL+    +  + P 
Sbjct: 202 EFSKLHNFLVEEEDLFLQRLNKEEEETKKKLNENTLKLNQTIASLKKLILEVGEKSQAPT 261

Query: 318 MALYLQQAKELINK 331
           + L LQ  KE++ +
Sbjct: 262 LEL-LQNPKEVLTR 274


>gi|89886468 fibronectin type III and SPRY domain containing 1-like
           isoform 1 [Homo sapiens]
          Length = 498

 Score = 67.0 bits (162), Expect = 3e-11
 Identities = 40/153 (26%), Positives = 81/153 (52%), Gaps = 1/153 (0%)

Query: 220 IAMLVAGNDRVQAVITQMEEVCQTIEDNSRRQKQLLNQRFESLCAVLEERKGELLQALAR 279
           I+ L   ND +Q  I  +    + +++NS      L++ F+SL ++L+E K  ++  + +
Sbjct: 12  ISTLANKNDEIQNFIDTLHHTLKGVQENSSNILSELDEEFDSLYSILDEVKESMINCIKQ 71

Query: 280 EQEEKLQRVRGLIRQYGDHLEASSKLVESAIQSMEEPQMALYLQQAKELINKVGAMSKVE 339
           EQ  K Q ++  I Q  + LE S +L+E A +S++  +   + + A+++ ++V   S   
Sbjct: 72  EQARKSQELQSQISQCNNALENSEELLEFATRSLDIKEPEEFSKAARQIKDRVTMASAFR 131

Query: 340 LAGRPEPGYESMEQFTVRVEHVAEMLRTIDFQP 372
           L+ +P+   ++M    V      +ML+T+ F P
Sbjct: 132 LSLKPKVS-DNMTHLMVDFSQERQMLQTLKFLP 163


>gi|223718222 fibronectin type III and SPRY domain containing 1-like
           isoform 3 [Homo sapiens]
          Length = 530

 Score = 67.0 bits (162), Expect = 3e-11
 Identities = 40/153 (26%), Positives = 81/153 (52%), Gaps = 1/153 (0%)

Query: 220 IAMLVAGNDRVQAVITQMEEVCQTIEDNSRRQKQLLNQRFESLCAVLEERKGELLQALAR 279
           I+ L   ND +Q  I  +    + +++NS      L++ F+SL ++L+E K  ++  + +
Sbjct: 44  ISTLANKNDEIQNFIDTLHHTLKGVQENSSNILSELDEEFDSLYSILDEVKESMINCIKQ 103

Query: 280 EQEEKLQRVRGLIRQYGDHLEASSKLVESAIQSMEEPQMALYLQQAKELINKVGAMSKVE 339
           EQ  K Q ++  I Q  + LE S +L+E A +S++  +   + + A+++ ++V   S   
Sbjct: 104 EQARKSQELQSQISQCNNALENSEELLEFATRSLDIKEPEEFSKAARQIKDRVTMASAFR 163

Query: 340 LAGRPEPGYESMEQFTVRVEHVAEMLRTIDFQP 372
           L+ +P+   ++M    V      +ML+T+ F P
Sbjct: 164 LSLKPKVS-DNMTHLMVDFSQERQMLQTLKFLP 195


>gi|145275183 tripartite motif protein 34 isoform 3 [Homo sapiens]
          Length = 270

 Score = 65.9 bits (159), Expect = 6e-11
 Identities = 66/286 (23%), Positives = 116/286 (40%), Gaps = 51/286 (17%)

Query: 19  NLEKQLICPICLEMFSKPVVILPCQHNLCRKCANDVFQASNPLWQSRGSTTVSSGGRFRC 78
           N+++++ CPICLE+ ++P + L C H+LCR C          +  S      S GG+  C
Sbjct: 8   NVQEEVTCPICLELLTEP-LSLDCGHSLCRAC----------ITVSNKEAVTSMGGKSSC 56

Query: 79  PSCRHEVVLDRHGVYGLQRNLLVENIIDIYKQESSRPLHSKAEQHLMCEEHEEEKINIYC 138
           P C      +      LQ N  + NI++  K+    P + K     +C +H  EK+ ++C
Sbjct: 57  PVCGISYSFEH-----LQANQHLANIVERLKEVKLSPDNGKKRD--LC-DHHGEKLLLFC 108

Query: 139 LSCEVPTCSLCKVFGAHKDCEVAPLPTIYKRQKKQDLTLLPRLECSGTNTTYCSLDLPSS 198
                  C LC+    H+         ++K  +++   +L RL+           D    
Sbjct: 109 KEDRKVICWLCERSQEHRGHHTVLTEEVFKECQEKLQAVLKRLKKEEEEAEKLEAD---- 164

Query: 199 SDPPILASQNTKIIDSELSDGIAMLVAGNDRVQAVITQMEEVCQTIEDNSRRQKQLLNQR 258
                        I  E +     +     R+Q    Q+  +      N+  Q++L  QR
Sbjct: 165 -------------IREEKTSWKYQVQTERQRIQTEFDQLRSIL-----NNEEQREL--QR 204

Query: 259 FESLCAVLEERKGELLQALAREQEEKLQRVRGLIRQYGDHLEASSK 304
                  LEE + + L   A E E++L + + L+R+    +E  S+
Sbjct: 205 -------LEEEEKKTLDKFA-EAEDELVQQKQLVRELISDVECRSQ 242


>gi|51477687 tripartite motif protein 34 isoform 1 [Homo sapiens]
          Length = 488

 Score = 65.9 bits (159), Expect = 6e-11
 Identities = 66/286 (23%), Positives = 116/286 (40%), Gaps = 51/286 (17%)

Query: 19  NLEKQLICPICLEMFSKPVVILPCQHNLCRKCANDVFQASNPLWQSRGSTTVSSGGRFRC 78
           N+++++ CPICLE+ ++P + L C H+LCR C          +  S      S GG+  C
Sbjct: 8   NVQEEVTCPICLELLTEP-LSLDCGHSLCRAC----------ITVSNKEAVTSMGGKSSC 56

Query: 79  PSCRHEVVLDRHGVYGLQRNLLVENIIDIYKQESSRPLHSKAEQHLMCEEHEEEKINIYC 138
           P C      +      LQ N  + NI++  K+    P + K     +C +H  EK+ ++C
Sbjct: 57  PVCGISYSFEH-----LQANQHLANIVERLKEVKLSPDNGKKRD--LC-DHHGEKLLLFC 108

Query: 139 LSCEVPTCSLCKVFGAHKDCEVAPLPTIYKRQKKQDLTLLPRLECSGTNTTYCSLDLPSS 198
                  C LC+    H+         ++K  +++   +L RL+           D    
Sbjct: 109 KEDRKVICWLCERSQEHRGHHTVLTEEVFKECQEKLQAVLKRLKKEEEEAEKLEAD---- 164

Query: 199 SDPPILASQNTKIIDSELSDGIAMLVAGNDRVQAVITQMEEVCQTIEDNSRRQKQLLNQR 258
                        I  E +     +     R+Q    Q+  +      N+  Q++L  QR
Sbjct: 165 -------------IREEKTSWKYQVQTERQRIQTEFDQLRSIL-----NNEEQREL--QR 204

Query: 259 FESLCAVLEERKGELLQALAREQEEKLQRVRGLIRQYGDHLEASSK 304
                  LEE + + L   A E E++L + + L+R+    +E  S+
Sbjct: 205 -------LEEEEKKTLDKFA-EAEDELVQQKQLVRELISDVECRSQ 242


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.316    0.133    0.388 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 16,595,219
Number of Sequences: 37866
Number of extensions: 784016
Number of successful extensions: 6359
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 161
Number of HSP's successfully gapped in prelim test: 384
Number of HSP's that attempted gapping in prelim test: 5255
Number of HSP's gapped (non-prelim): 1234
length of query: 400
length of database: 18,247,518
effective HSP length: 104
effective length of query: 296
effective length of database: 14,309,454
effective search space: 4235598384
effective search space used: 4235598384
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 63 (28.9 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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