Guide to the Human Genome
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Search of human proteins with 77874206

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|77874206 poly(A) polymerase beta (testis specific) [Homo
sapiens]
         (637 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|77874206 poly(A) polymerase beta (testis specific) [Homo sapi...  1269   0.0  
gi|32490557 poly(A) polymerase alpha [Homo sapiens]                  1067   0.0  
gi|16306568 poly(A) polymerase gamma [Homo sapiens]                   762   0.0  
gi|42476164 POU class 2 homeobox 1 [Homo sapiens]                      38   0.025
gi|126362971 serine/threonine kinase 10 [Homo sapiens]                 35   0.16 
gi|189571674 cadherin-like 23 isoform 1 precursor [Homo sapiens]       35   0.21 
gi|19557645 secretogranin III [Homo sapiens]                           34   0.36 
gi|223029500 EF-hand calcium binding domain 5 isoform b [Homo sa...    33   0.80 
gi|90652855 EF-hand calcium binding domain 5 isoform a [Homo sap...    33   0.80 
gi|62865633 Sp3 transcription factor isoform 2 [Homo sapiens]          33   1.0  
gi|38373693 Sp3 transcription factor isoform 1 [Homo sapiens]          33   1.0  
gi|13376810 enhancer of polycomb 1 [Homo sapiens]                      33   1.0  
gi|71051596 coiled-coil domain containing 7 [Homo sapiens]             32   1.8  
gi|37059792 coiled-coil domain containing 7 [Homo sapiens]             32   1.8  
gi|11545785 NOL1/NOP2/Sun domain family, member 3 [Homo sapiens]       32   2.3  
gi|39752673 SH3 and cysteine rich domain 2 [Homo sapiens]              31   3.0  
gi|169214154 PREDICTED: hypothetical protein [Homo sapiens]            31   4.0  
gi|169213511 PREDICTED: hypothetical protein [Homo sapiens]            31   4.0  
gi|49087132 sal-like 2 [Homo sapiens]                                  31   4.0  
gi|64085252 hypothetical protein LOC145508 [Homo sapiens]              31   4.0  
gi|40068051 cyclin M2 isoform 3 [Homo sapiens]                         31   4.0  
gi|40068055 cyclin M2 isoform 2 [Homo sapiens]                         31   4.0  
gi|40068053 cyclin M2 isoform 1 [Homo sapiens]                         31   4.0  
gi|167000400 gamma-aminobutyric acid (GABA) B receptor 1 isoform...    30   5.2  
gi|11497612 gamma-aminobutyric acid (GABA) B receptor 1 isoform ...    30   5.2  
gi|10835015 gamma-aminobutyric acid (GABA) B receptor 1 isoform ...    30   5.2  
gi|39812378 RAN binding protein 9 [Homo sapiens]                       30   5.2  
gi|223468681 v-rel reticuloendotheliosis viral oncogene homolog ...    30   6.8  
gi|223468676 v-rel reticuloendotheliosis viral oncogene homolog ...    30   6.8  
gi|120587025 SH3 and multiple ankyrin repeat domains 1 [Homo sap...    30   6.8  

>gi|77874206 poly(A) polymerase beta (testis specific) [Homo
           sapiens]
          Length = 637

 Score = 1269 bits (3284), Expect = 0.0
 Identities = 637/637 (100%), Positives = 637/637 (100%)

Query: 1   MMPFPVTTQGPPQPAPPPNRYGVSSPISLAVPKETDCLLTQRLIETLRPFGVFEEEEELQ 60
           MMPFPVTTQGPPQPAPPPNRYGVSSPISLAVPKETDCLLTQRLIETLRPFGVFEEEEELQ
Sbjct: 1   MMPFPVTTQGPPQPAPPPNRYGVSSPISLAVPKETDCLLTQRLIETLRPFGVFEEEEELQ 60

Query: 61  RRILVLEKLNNLVKEWIREISESKSLPQSVIENVGGKIFTFGSYRLGVHTKGADIDALCV 120
           RRILVLEKLNNLVKEWIREISESKSLPQSVIENVGGKIFTFGSYRLGVHTKGADIDALCV
Sbjct: 61  RRILVLEKLNNLVKEWIREISESKSLPQSVIENVGGKIFTFGSYRLGVHTKGADIDALCV 120

Query: 121 APSHVDRSDFFTSFYAKLKLQEEVKDLRAVEEAFVPVIKLCFDGIEIDILFARLALQTIP 180
           APSHVDRSDFFTSFYAKLKLQEEVKDLRAVEEAFVPVIKLCFDGIEIDILFARLALQTIP
Sbjct: 121 APSHVDRSDFFTSFYAKLKLQEEVKDLRAVEEAFVPVIKLCFDGIEIDILFARLALQTIP 180

Query: 181 EDLDLRDDSLLKNLDIRCIRSLNGCRVTDEILHLVPNIDNFRLTLRAIKLWAKCHNIYSN 240
           EDLDLRDDSLLKNLDIRCIRSLNGCRVTDEILHLVPNIDNFRLTLRAIKLWAKCHNIYSN
Sbjct: 181 EDLDLRDDSLLKNLDIRCIRSLNGCRVTDEILHLVPNIDNFRLTLRAIKLWAKCHNIYSN 240

Query: 241 ILGFLGGVSWAMLVARTCQLYPNAVASTLVRKFFLVFSEWEWPNPVLLKEPEERNLNLPV 300
           ILGFLGGVSWAMLVARTCQLYPNAVASTLVRKFFLVFSEWEWPNPVLLKEPEERNLNLPV
Sbjct: 241 ILGFLGGVSWAMLVARTCQLYPNAVASTLVRKFFLVFSEWEWPNPVLLKEPEERNLNLPV 300

Query: 301 WDPRVNPSDRYHLMPIITPAYPQQNSTYNVSISTRMVMIEEFKQGLAITHEILLSKAEWS 360
           WDPRVNPSDRYHLMPIITPAYPQQNSTYNVSISTRMVMIEEFKQGLAITHEILLSKAEWS
Sbjct: 301 WDPRVNPSDRYHLMPIITPAYPQQNSTYNVSISTRMVMIEEFKQGLAITHEILLSKAEWS 360

Query: 361 KLFEAPSFFQKYKHYIVLLASASTEKQHLEWVGLVESKIRILVGSLEKNEFITLAHVNPQ 420
           KLFEAPSFFQKYKHYIVLLASASTEKQHLEWVGLVESKIRILVGSLEKNEFITLAHVNPQ
Sbjct: 361 KLFEAPSFFQKYKHYIVLLASASTEKQHLEWVGLVESKIRILVGSLEKNEFITLAHVNPQ 420

Query: 421 SFPAPKENPDMEEFRTMWVIGLGLKKPDNSEILSIDLTYDIQSFTDTVYRQAVNSKMFEM 480
           SFPAPKENPDMEEFRTMWVIGLGLKKPDNSEILSIDLTYDIQSFTDTVYRQAVNSKMFEM
Sbjct: 421 SFPAPKENPDMEEFRTMWVIGLGLKKPDNSEILSIDLTYDIQSFTDTVYRQAVNSKMFEM 480

Query: 481 GMKITAMHLRRKELHQLLPHHVLQDKKAHSTEGRRLTDLNDSSFDLSAGCENSMSVPSST 540
           GMKITAMHLRRKELHQLLPHHVLQDKKAHSTEGRRLTDLNDSSFDLSAGCENSMSVPSST
Sbjct: 481 GMKITAMHLRRKELHQLLPHHVLQDKKAHSTEGRRLTDLNDSSFDLSAGCENSMSVPSST 540

Query: 541 STMKTGPLISSSQGRNSPALAVMTASVANIQATEFSLQQVNTNESSGVALNESIPHAVSQ 600
           STMKTGPLISSSQGRNSPALAVMTASVANIQATEFSLQQVNTNESSGVALNESIPHAVSQ
Sbjct: 541 STMKTGPLISSSQGRNSPALAVMTASVANIQATEFSLQQVNTNESSGVALNESIPHAVSQ 600

Query: 601 PAISPSPKAMVARVVSSTCLISHPDLQETQQQTYLIL 637
           PAISPSPKAMVARVVSSTCLISHPDLQETQQQTYLIL
Sbjct: 601 PAISPSPKAMVARVVSSTCLISHPDLQETQQQTYLIL 637


>gi|32490557 poly(A) polymerase alpha [Homo sapiens]
          Length = 745

 Score = 1067 bits (2759), Expect = 0.0
 Identities = 538/625 (86%), Positives = 569/625 (91%), Gaps = 2/625 (0%)

Query: 2   MPFPVTTQGPPQPAPPPNRYGVSSPISLAVPKETDCLLTQRLIETLRPFGVFEEEEELQR 61
           MPFPVTTQG  Q  PP   YG++SPISLA PKETDC+LTQ+LIETL+PFGVFEEEEELQR
Sbjct: 1   MPFPVTTQGSQQTQPPQKHYGITSPISLAAPKETDCVLTQKLIETLKPFGVFEEEEELQR 60

Query: 62  RILVLEKLNNLVKEWIREISESKSLPQSVIENVGGKIFTFGSYRLGVHTKGADIDALCVA 121
           RIL+L KLNNLVKEWIREISESK+LPQSVIENVGGKIFTFGSYRLGVHTKGADIDALCVA
Sbjct: 61  RILILGKLNNLVKEWIREISESKNLPQSVIENVGGKIFTFGSYRLGVHTKGADIDALCVA 120

Query: 122 PSHVDRSDFFTSFYAKLKLQEEVKDLRAVEEAFVPVIKLCFDGIEIDILFARLALQTIPE 181
           P HVDRSDFFTSFY KLKLQEEVKDLRAVEEAFVPVIKLCFDGIEIDILFARLALQTIPE
Sbjct: 121 PRHVDRSDFFTSFYDKLKLQEEVKDLRAVEEAFVPVIKLCFDGIEIDILFARLALQTIPE 180

Query: 182 DLDLRDDSLLKNLDIRCIRSLNGCRVTDEILHLVPNIDNFRLTLRAIKLWAKCHNIYSNI 241
           DLDLRDDSLLKNLDIRCIRSLNGCRVTDEILHLVPNIDNFRLTLRAIKLWAK HNIYSNI
Sbjct: 181 DLDLRDDSLLKNLDIRCIRSLNGCRVTDEILHLVPNIDNFRLTLRAIKLWAKRHNIYSNI 240

Query: 242 LGFLGGVSWAMLVARTCQLYPNAVASTLVRKFFLVFSEWEWPNPVLLKEPEERNLNLPVW 301
           LGFLGGVSWAMLVARTCQLYPNA+ASTLV KFFLVFS+WEWPNPVLLK+PEE NLNLPVW
Sbjct: 241 LGFLGGVSWAMLVARTCQLYPNAIASTLVHKFFLVFSKWEWPNPVLLKQPEECNLNLPVW 300

Query: 302 DPRVNPSDRYHLMPIITPAYPQQNSTYNVSISTRMVMIEEFKQGLAITHEILLSKAEWSK 361
           DPRVNPSDRYHLMPIITPAYPQQNSTYNVS+STRMVM+EEFKQGLAIT EILLSKAEWSK
Sbjct: 301 DPRVNPSDRYHLMPIITPAYPQQNSTYNVSVSTRMVMVEEFKQGLAITDEILLSKAEWSK 360

Query: 362 LFEAPSFFQKYKHYIVLLASASTEKQHLEWVGLVESKIRILVGSLEKNEFITLAHVNPQS 421
           LFEAP+FFQKYKHYIVLLASA TEKQ LEWVGLVESKIRILVGSLEKNEFITLAHVNPQS
Sbjct: 361 LFEAPNFFQKYKHYIVLLASAPTEKQRLEWVGLVESKIRILVGSLEKNEFITLAHVNPQS 420

Query: 422 FPAPKENPDMEEFRTMWVIGLGLKKPDNSEILSIDLTYDIQSFTDTVYRQAVNSKMFEMG 481
           FPAPKENPD EEFRTMWVIGL  KK +NSE LS+DLTYDIQSFTDTVYRQA+NSKMFE+ 
Sbjct: 421 FPAPKENPDKEEFRTMWVIGLVFKKTENSENLSVDLTYDIQSFTDTVYRQAINSKMFEVD 480

Query: 482 MKITAMHLRRKELHQLLPHHVLQDKKAHSTEGRRLTDLNDSSFDLSAGCENSMSVPSSTS 541
           MKI AMH++RK+LHQLLP+HVLQ KK HSTEG +LT LNDSS DLS   +NSMSVPS TS
Sbjct: 481 MKIAAMHVKRKQLHQLLPNHVLQKKKKHSTEGVKLTALNDSSLDLSMDSDNSMSVPSPTS 540

Query: 542 TMKTGPLIS--SSQGRNSPALAVMTASVANIQATEFSLQQVNTNESSGVALNESIPHAVS 599
             KT PL S  SSQGRNSPA AV  ASV NIQATE S+ QVN++ESSG   +ESIP   +
Sbjct: 541 ATKTSPLNSSGSSQGRNSPAPAVTAASVTNIQATEVSVPQVNSSESSGGTSSESIPQTAT 600

Query: 600 QPAISPSPKAMVARVVSSTCLISHP 624
           QPAISP PK  V+RVVSST L++ P
Sbjct: 601 QPAISPPPKPTVSRVVSSTRLVNPP 625


>gi|16306568 poly(A) polymerase gamma [Homo sapiens]
          Length = 736

 Score =  762 bits (1967), Expect = 0.0
 Identities = 379/542 (69%), Positives = 448/542 (82%), Gaps = 7/542 (1%)

Query: 21  YGVSSPISLAVPKETDCLLTQRLIETLRPFGVFEEEEELQRRILVLEKLNNLVKEWIREI 80
           YG++SPISLA PKE D + TQ+LI+ ++PFGVFE+EEEL  R++VL KLNNLVKEWI ++
Sbjct: 19  YGITSPISLASPKEIDHIYTQKLIDAMKPFGVFEDEEELNHRLVVLGKLNNLVKEWISDV 78

Query: 81  SESKSLPQSVIENVGGKIFTFGSYRLGVHTKGADIDALCVAPSHVDRSDFFTSFYAKLKL 140
           SESK+LP SV+  VGGKIFTFGSYRLGVHTKGADIDALCVAP HV+RSDFF SF+ KLK 
Sbjct: 79  SESKNLPPSVVATVGGKIFTFGSYRLGVHTKGADIDALCVAPRHVERSDFFQSFFEKLKH 138

Query: 141 QEEVKDLRAVEEAFVPVIKLCFDGIEIDILFARLALQTIPEDLDLRDDSLLKNLDIRCIR 200
           Q+ +++LRAVE+AFVPVIK  FDGIEID++FARLA+QTI ++LDLRDDS L++LDIRCIR
Sbjct: 139 QDGIRNLRAVEDAFVPVIKFEFDGIEIDLVFARLAIQTISDNLDLRDDSRLRSLDIRCIR 198

Query: 201 SLNGCRVTDEILHLVPNIDNFRLTLRAIKLWAKCHNIYSNILGFLGGVSWAMLVARTCQL 260
           SLNGCRVTDEILHLVPN + FRLTLRA+KLWAK   IYSN+LGFLGGVSWAMLVARTCQL
Sbjct: 199 SLNGCRVTDEILHLVPNKETFRLTLRAVKLWAKRRGIYSNMLGFLGGVSWAMLVARTCQL 258

Query: 261 YPNAVASTLVRKFFLVFSEWEWPNPVLLKEPEERNLNLPVWDPRVNPSDRYHLMPIITPA 320
           YPNA ASTLV KFFLVFS+WEWPNPVLLK+PEE NLNLPVWDPRVNPSDRYHLMPIITPA
Sbjct: 259 YPNAAASTLVHKFFLVFSKWEWPNPVLLKQPEESNLNLPVWDPRVNPSDRYHLMPIITPA 318

Query: 321 YPQQNSTYNVSISTRMVMIEEFKQGLAITHEILLSKAEWSKLFEAPSFFQKYKHYIVLLA 380
           YPQQNSTYNVS STR VM+EEFKQGLA+T EIL  K++WSKL E P+FFQKY+HYIVL A
Sbjct: 319 YPQQNSTYNVSTSTRTVMVEEFKQGLAVTDEILQGKSDWSKLLEPPNFFQKYRHYIVLTA 378

Query: 381 SASTEKQHLEWVGLVESKIRILVGSLEKNEFITLAHVNPQSFPAPKENPDMEEFRTMWVI 440
           SASTE+ HLEWVGLVESKIR+LVG+LE+NEFITLAHVNPQSFP  KE+     + +MW +
Sbjct: 379 SASTEENHLEWVGLVESKIRVLVGNLERNEFITLAHVNPQSFPGNKEHHKDNNYVSMWFL 438

Query: 441 GLGLKKPDNSEILSIDLTYDIQSFTDTVYRQAVNSKMFEMGMKITAMHLRRKELHQLLPH 500
           G+  ++ +N+E ++IDLTYDIQSFTDTVYRQA N  M + GMKI A H+++K+LH  LP 
Sbjct: 439 GIIFRRVENAESVNIDLTYDIQSFTDTVYRQANNINMLKEGMKIEATHVKKKQLHHYLPA 498

Query: 501 HVLQDKKAHSTEGRRLTDLNDSSFDLSAG--CENSMSVPSSTSTMKTGPLISSSQGRNSP 558
            +LQ KK  S     L+D+N SS  L +     +S  + SS  T    P  S +   +SP
Sbjct: 499 EILQKKKKQS-----LSDVNRSSGGLQSKRLSLDSSCLDSSRDTDNGTPFNSPASKSDSP 553

Query: 559 AL 560
           ++
Sbjct: 554 SV 555


>gi|42476164 POU class 2 homeobox 1 [Homo sapiens]
          Length = 743

 Score = 38.1 bits (87), Expect = 0.025
 Identities = 27/86 (31%), Positives = 45/86 (52%), Gaps = 5/86 (5%)

Query: 537 PSSTSTMKTGP-LISSSQGRN---SPALAVMTASVANIQATEFSLQQVNTNESSGVALNE 592
           PS TS + T P L++SS       SP L + +A+V N+  T  S    + N ++ ++   
Sbjct: 455 PSPTSLVATTPSLVTSSAATTLTVSPVLPLTSAAVTNLSVTGTS-DTTSNNTATVISTAP 513

Query: 593 SIPHAVSQPAISPSPKAMVARVVSST 618
               AV+ P++SPSP A  +   +S+
Sbjct: 514 PASSAVTSPSLSPSPSASASTSEASS 539


>gi|126362971 serine/threonine kinase 10 [Homo sapiens]
          Length = 968

 Score = 35.4 bits (80), Expect = 0.16
 Identities = 48/207 (23%), Positives = 84/207 (40%), Gaps = 36/207 (17%)

Query: 8   TQGPPQPAPPPNRYGVSSPISLAVPKETDCLLTQRLIETLRPFGVFEEEEELQRRILVLE 67
           T  PP  AP  N  G++ P+ L                  RP  +    +  Q +  V E
Sbjct: 390 TTSPPVVAPG-NENGLAVPVPL---------------RKSRPVSMDARIQVAQEK-QVAE 432

Query: 68  KLNNLVKEWIREISESKSLPQS-VIENVGGKIFTFGSYRL------GVHTKGADIDALCV 120
           +  +L     R    S+S P S  +E +GG+    GS         G   + +D  +LC 
Sbjct: 433 QGGDLSPAANRSQKASQSRPNSSALETLGGEKLANGSLEPPAQAAPGPSKRDSDCSSLCT 492

Query: 121 APSHVDRSDFFTSFYAKLKLQEE-----VKDLRAVEEAFVPVIKLCFDGIEIDILFARLA 175
           + S     D+ T+    L L +E     +KD +  ++      K   DG+E+ I  +++ 
Sbjct: 493 SES----MDYGTNLSTDLSLNKEMGSLSIKDPKLYKKTLKRTRKFVVDGVEVSITTSKII 548

Query: 176 LQTIPEDLDLRDDSLLKNLDIRCIRSL 202
            +   +D ++R    L+  ++R +R L
Sbjct: 549 SEDEKKDEEMR---FLRRQELRELRLL 572


>gi|189571674 cadherin-like 23 isoform 1 precursor [Homo sapiens]
          Length = 3354

 Score = 35.0 bits (79), Expect = 0.21
 Identities = 32/136 (23%), Positives = 54/136 (39%), Gaps = 6/136 (4%)

Query: 290  EPEERNLNLPVWDPRVNPSDRYHLMPIITP-----AYPQQNSTYNVSISTRMVMIEE-FK 343
            EP     N+   D  +NP   YH++ I+         P Q   + V+I+T  VM++    
Sbjct: 2188 EPGTVIANITAIDHDLNPKLEYHIVGIVAKDDTDRLVPNQEDAFAVNINTGSVMVKSPMN 2247

Query: 344  QGLAITHEILLSKAEWSKLFEAPSFFQKYKHYIVLLASASTEKQHLEWVGLVESKIRILV 403
            + L  T+E+ LS  + +      S         V +   +      +  G+     RIL 
Sbjct: 2248 RELVATYEVTLSVIDNASDLPERSVSVPNAKLTVNVLDVNDNTPQFKPFGITYYMERILE 2307

Query: 404  GSLEKNEFITLAHVNP 419
            G+      I +A V+P
Sbjct: 2308 GATPGTTLIAVAAVDP 2323


>gi|19557645 secretogranin III [Homo sapiens]
          Length = 468

 Score = 34.3 bits (77), Expect = 0.36
 Identities = 37/187 (19%), Positives = 73/187 (39%), Gaps = 27/187 (14%)

Query: 27  ISLAVPKETDCLLTQRLIETLRPFGVFEEEEELQRRILVLEKLNNLVKEWIREISESKSL 86
           I+  + +E D  +  +++  L   G+  E +       V E L  L+ +      E  + 
Sbjct: 155 IAARIYEENDRAVFDKIVSKLLNLGLITESQAHTLEDEVAEVLQKLISKEANNYEEDPNK 214

Query: 87  PQSVIENVGGKIFTFGSYRLGVH------------------TKGADIDALCVAPSHVDRS 128
           P S  EN  GKI    +    +                   T G +      +  + +  
Sbjct: 215 PTSWTENQAGKIPEKVTPMAAIQDGLAKGENDETVSNTLTLTNGLERRTKTYSEDNFEEL 274

Query: 129 DFFTSFYAKLKLQEEVKDLRAVEEAFVPVIKLCFDGIEIDILFARLALQTIPEDLDLRDD 188
            +F +FYA LK  +  K+ +  +E  + ++K   D +++ + +  ++    PE+      
Sbjct: 275 QYFPNFYALLKSIDSEKEAKE-KETLITIMKTLIDFVKMMVKYGTIS----PEE----GV 325

Query: 189 SLLKNLD 195
           S L+NLD
Sbjct: 326 SYLENLD 332


>gi|223029500 EF-hand calcium binding domain 5 isoform b [Homo
           sapiens]
          Length = 856

 Score = 33.1 bits (74), Expect = 0.80
 Identities = 28/97 (28%), Positives = 47/97 (48%), Gaps = 6/97 (6%)

Query: 67  EKLNNLVKEWIREISESKSLPQSVIENVGGKIFTFGSYRLGVHTKGADI-DALCVAPSHV 125
           + L     EWI  +     +P+SVI+NV  + F    ++LG H K  DI D+     + +
Sbjct: 231 QALQEQFDEWI--LDPKGMIPKSVIQNVLQEFFQNPDFKLGSHCKQLDITDSTEPRLNKM 288

Query: 126 DRSDFFTSFYAKLK---LQEEVKDLRAVEEAFVPVIK 159
           + +++ +S    LK    +E +K L    + F  VIK
Sbjct: 289 EFTEYISSHIKDLKSEMFEELLKHLCHSADEFREVIK 325


>gi|90652855 EF-hand calcium binding domain 5 isoform a [Homo
           sapiens]
          Length = 1503

 Score = 33.1 bits (74), Expect = 0.80
 Identities = 28/97 (28%), Positives = 47/97 (48%), Gaps = 6/97 (6%)

Query: 67  EKLNNLVKEWIREISESKSLPQSVIENVGGKIFTFGSYRLGVHTKGADI-DALCVAPSHV 125
           + L     EWI  +     +P+SVI+NV  + F    ++LG H K  DI D+     + +
Sbjct: 287 QALQEQFDEWI--LDPKGMIPKSVIQNVLQEFFQNPDFKLGSHCKQLDITDSTEPRLNKM 344

Query: 126 DRSDFFTSFYAKLK---LQEEVKDLRAVEEAFVPVIK 159
           + +++ +S    LK    +E +K L    + F  VIK
Sbjct: 345 EFTEYISSHIKDLKSEMFEELLKHLCHSADEFREVIK 381


>gi|62865633 Sp3 transcription factor isoform 2 [Homo sapiens]
          Length = 713

 Score = 32.7 bits (73), Expect = 1.0
 Identities = 34/129 (26%), Positives = 59/129 (45%), Gaps = 14/129 (10%)

Query: 519 LNDSSFDLSAGCE-------NSMSVPSSTSTMKTGPLISS--SQGRNSPALAVMTASVAN 569
           L+ SS  ++AG            ++ SS ++ +TG  +S   ++      L V T+S + 
Sbjct: 211 LSGSSQTMTAGINADGHLINTGQAMDSSDNSERTGERVSPDINETNTDTDLFVPTSSSSQ 270

Query: 570 IQATEFS--LQQVNTNE---SSGVALNESIPHAVSQPAISPSPKAMVARVVSSTCLISHP 624
           +  T  S  + Q NTN    SSG   +  +     Q  +S   +A   +V ++  ++ H 
Sbjct: 271 LPVTIDSTGILQQNTNSLTTSSGQVHSSDLQGNYIQSPVSEETQAQNIQVSTAQPVVQHL 330

Query: 625 DLQETQQQT 633
            LQE+QQ T
Sbjct: 331 QLQESQQPT 339


>gi|38373693 Sp3 transcription factor isoform 1 [Homo sapiens]
          Length = 781

 Score = 32.7 bits (73), Expect = 1.0
 Identities = 34/129 (26%), Positives = 59/129 (45%), Gaps = 14/129 (10%)

Query: 519 LNDSSFDLSAGCE-------NSMSVPSSTSTMKTGPLISS--SQGRNSPALAVMTASVAN 569
           L+ SS  ++AG            ++ SS ++ +TG  +S   ++      L V T+S + 
Sbjct: 279 LSGSSQTMTAGINADGHLINTGQAMDSSDNSERTGERVSPDINETNTDTDLFVPTSSSSQ 338

Query: 570 IQATEFS--LQQVNTNE---SSGVALNESIPHAVSQPAISPSPKAMVARVVSSTCLISHP 624
           +  T  S  + Q NTN    SSG   +  +     Q  +S   +A   +V ++  ++ H 
Sbjct: 339 LPVTIDSTGILQQNTNSLTTSSGQVHSSDLQGNYIQSPVSEETQAQNIQVSTAQPVVQHL 398

Query: 625 DLQETQQQT 633
            LQE+QQ T
Sbjct: 399 QLQESQQPT 407


>gi|13376810 enhancer of polycomb 1 [Homo sapiens]
          Length = 836

 Score = 32.7 bits (73), Expect = 1.0
 Identities = 31/123 (25%), Positives = 53/123 (43%), Gaps = 9/123 (7%)

Query: 497 LLPHHVLQDKKAHSTEGRRLTDLNDSSFDLSAGCENSMSVPSSTSTMKTGPLISSSQGRN 556
           L P ++ Q   +HS    ++T  N ++  +  G    ++VPSS +T+ +   I+    R+
Sbjct: 720 LQPSNITQTSSSHSALSHQVTAANSATTQVLIGNNIRLTVPSSVATVNS---IAPINARH 776

Query: 557 SPALAVMTASVANIQATEFSLQQVNTNESSGVALNESIP---HAVSQPAISPSPKAMVAR 613
            P       S A   A   + Q      SS V   +S+P   H   +PA++      VA 
Sbjct: 777 IPRTLSAVPSSALKLAAAANCQVSKVPSSSSV---DSVPRENHESEKPALNNIADNTVAM 833

Query: 614 VVS 616
            V+
Sbjct: 834 EVT 836


>gi|71051596 coiled-coil domain containing 7 [Homo sapiens]
          Length = 486

 Score = 32.0 bits (71), Expect = 1.8
 Identities = 28/116 (24%), Positives = 55/116 (47%), Gaps = 8/116 (6%)

Query: 445 KKPDNSEILSIDLTYDIQSFTDTVYRQA---VNSKMFEMGMKITAMHLRRKELHQLLPHH 501
           K  D+ + +S +  + I+   D V + A   + +K+ +  +K  A+    K  HQL  ++
Sbjct: 354 KSEDSEKKMSPEKEFKIKEDLDQVQKVARLEIENKVLQEQLK-QALQEAEKAKHQL--NY 410

Query: 502 VLQDKKAHSTEGRRLTDLNDSSFDLSAGCENSMSVPSSTSTMKTGPLISSSQGRNS 557
            L  +K   +EG+  T +   +       E+S ++P    T K+  L+S S G+ +
Sbjct: 411 FLNQEKLLKSEGKTETTMQVGNSQTKVKGEDSKNIPLEKETRKS--LVSDSGGQRT 464


>gi|37059792 coiled-coil domain containing 7 [Homo sapiens]
          Length = 486

 Score = 32.0 bits (71), Expect = 1.8
 Identities = 28/116 (24%), Positives = 55/116 (47%), Gaps = 8/116 (6%)

Query: 445 KKPDNSEILSIDLTYDIQSFTDTVYRQA---VNSKMFEMGMKITAMHLRRKELHQLLPHH 501
           K  D+ + +S +  + I+   D V + A   + +K+ +  +K  A+    K  HQL  ++
Sbjct: 354 KSEDSEKKMSPEKEFKIKEDLDQVQKVARLEIENKVLQEQLK-QALQEAEKAKHQL--NY 410

Query: 502 VLQDKKAHSTEGRRLTDLNDSSFDLSAGCENSMSVPSSTSTMKTGPLISSSQGRNS 557
            L  +K   +EG+  T +   +       E+S ++P    T K+  L+S S G+ +
Sbjct: 411 FLNQEKLLKSEGKTETTMQVGNSQTKVKGEDSKNIPLEKETRKS--LVSDSGGQRT 464


>gi|11545785 NOL1/NOP2/Sun domain family, member 3 [Homo sapiens]
          Length = 340

 Score = 31.6 bits (70), Expect = 2.3
 Identities = 22/75 (29%), Positives = 33/75 (44%), Gaps = 5/75 (6%)

Query: 491 RKELHQLLPHHVLQDKKAHSTEGRRLTDLNDSSFD---LSAGCENSMSVPSSTSTMKTGP 547
           R+ L   +P  ++   K    +GR++ D     FD   + A C N  S   S+ + K   
Sbjct: 172 RQTLESFIPQPLINVIKVSELDGRKMGDAQPEMFDKVLVDAPCSNDRSWLFSSDSQKASC 231

Query: 548 LISSSQGRNSPALAV 562
            I  SQ RN P L +
Sbjct: 232 RI--SQRRNLPLLQI 244


>gi|39752673 SH3 and cysteine rich domain 2 [Homo sapiens]
          Length = 411

 Score = 31.2 bits (69), Expect = 3.0
 Identities = 18/63 (28%), Positives = 30/63 (47%), Gaps = 1/63 (1%)

Query: 11  PPQPAPPPNRYGVSSPISLAVPKETDCLLTQRLIETLRPFGVFEEEEELQRRILVLEKLN 70
           PP P PPP+    +S   LA P  + C +  R +  L+P  +   +E + +R    E  +
Sbjct: 70  PPTPLPPPSPPPTASDRGLATPSPSPCPV-PRPLAALKPVRLHSFQEHVFKRASPCELCH 128

Query: 71  NLV 73
            L+
Sbjct: 129 QLI 131


>gi|169214154 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 737

 Score = 30.8 bits (68), Expect = 4.0
 Identities = 24/122 (19%), Positives = 49/122 (40%), Gaps = 4/122 (3%)

Query: 497 LLPHHVLQDKKAHSTEGRRLTDLNDSSFDLSAGCENSMSVPSSTSTMKTGPLISSSQGRN 556
           +L HH L      ST     T    +S  +++    S S+ S++ST       ++S    
Sbjct: 102 VLSHHTLHITSNSSTSSSSTTSSTSTSSFITSSFTTSTSITSTSSTSS----FTTSTATT 157

Query: 557 SPALAVMTASVANIQATEFSLQQVNTNESSGVALNESIPHAVSQPAISPSPKAMVARVVS 616
           S ++++ + S  +   T  S    +T+ +S  +   S   + S    + +     +   +
Sbjct: 158 STSISITSTSSISSSITSTSTSTTSTSSNSTTSTVTSTSTSTSTSTSTSTSSTFTSTTST 217

Query: 617 ST 618
           ST
Sbjct: 218 ST 219


>gi|169213511 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 737

 Score = 30.8 bits (68), Expect = 4.0
 Identities = 24/122 (19%), Positives = 49/122 (40%), Gaps = 4/122 (3%)

Query: 497 LLPHHVLQDKKAHSTEGRRLTDLNDSSFDLSAGCENSMSVPSSTSTMKTGPLISSSQGRN 556
           +L HH L      ST     T    +S  +++    S S+ S++ST       ++S    
Sbjct: 102 VLSHHTLHITSNSSTSSSSTTSSTSTSSFITSSFTTSTSITSTSSTSS----FTTSTATT 157

Query: 557 SPALAVMTASVANIQATEFSLQQVNTNESSGVALNESIPHAVSQPAISPSPKAMVARVVS 616
           S ++++ + S  +   T  S    +T+ +S  +   S   + S    + +     +   +
Sbjct: 158 STSISITSTSSISSSITSTSTSTTSTSSNSTTSTVTSTSTSTSTSTSTSTSSTFTSTTST 217

Query: 617 ST 618
           ST
Sbjct: 218 ST 219


>gi|49087132 sal-like 2 [Homo sapiens]
          Length = 1007

 Score = 30.8 bits (68), Expect = 4.0
 Identities = 22/70 (31%), Positives = 35/70 (50%), Gaps = 7/70 (10%)

Query: 5   PVTTQGPPQPAPPPNRYGV-SSPISLAVPKETDCLLTQRLIETLRPFGVFEEEEELQRRI 63
           P +T  PP P PPP   GV S  +++ +  E   +L QR I  +      +  E++ R++
Sbjct: 154 PESTPAPPPPPPPPPPPGVGSGHLNIPLILEELRVLQQRQIHQM------QMTEQICRQV 207

Query: 64  LVLEKLNNLV 73
           L+L  L   V
Sbjct: 208 LLLGSLGQTV 217


>gi|64085252 hypothetical protein LOC145508 [Homo sapiens]
          Length = 1094

 Score = 30.8 bits (68), Expect = 4.0
 Identities = 16/44 (36%), Positives = 25/44 (56%), Gaps = 1/44 (2%)

Query: 491 RKELHQLLPHHVLQDKKAHSTEGRRLTDLNDSSFDLSAGCENSM 534
           RKEL+ +L    LQ+++ HS E  +L D+     DL    +NS+
Sbjct: 543 RKELNDVLTKRALQEEELHSKE-EKLRDIKSHQADLELEVKNSL 585


>gi|40068051 cyclin M2 isoform 3 [Homo sapiens]
          Length = 552

 Score = 30.8 bits (68), Expect = 4.0
 Identities = 21/69 (30%), Positives = 31/69 (44%), Gaps = 7/69 (10%)

Query: 26  PISLAVPKETDCLLTQRLIETLRPFGVFEEEEELQRRILVLEKLNNLVKEWIREISESKS 85
           P S  V K  DC+L Q +       G     E+L   + V +  N+LVKE +  I  +  
Sbjct: 388 PASYPVSKLLDCVLGQEI-------GTVYNREKLLEMLRVTDPYNDLVKEELNIIQGALE 440

Query: 86  LPQSVIENV 94
           L    +E+V
Sbjct: 441 LRTKTVEDV 449


>gi|40068055 cyclin M2 isoform 2 [Homo sapiens]
          Length = 853

 Score = 30.8 bits (68), Expect = 4.0
 Identities = 21/69 (30%), Positives = 31/69 (44%), Gaps = 7/69 (10%)

Query: 26  PISLAVPKETDCLLTQRLIETLRPFGVFEEEEELQRRILVLEKLNNLVKEWIREISESKS 85
           P S  V K  DC+L Q +       G     E+L   + V +  N+LVKE +  I  +  
Sbjct: 388 PASYPVSKLLDCVLGQEI-------GTVYNREKLLEMLRVTDPYNDLVKEELNIIQGALE 440

Query: 86  LPQSVIENV 94
           L    +E+V
Sbjct: 441 LRTKTVEDV 449


>gi|40068053 cyclin M2 isoform 1 [Homo sapiens]
          Length = 875

 Score = 30.8 bits (68), Expect = 4.0
 Identities = 21/69 (30%), Positives = 31/69 (44%), Gaps = 7/69 (10%)

Query: 26  PISLAVPKETDCLLTQRLIETLRPFGVFEEEEELQRRILVLEKLNNLVKEWIREISESKS 85
           P S  V K  DC+L Q +       G     E+L   + V +  N+LVKE +  I  +  
Sbjct: 388 PASYPVSKLLDCVLGQEI-------GTVYNREKLLEMLRVTDPYNDLVKEELNIIQGALE 440

Query: 86  LPQSVIENV 94
           L    +E+V
Sbjct: 441 LRTKTVEDV 449


>gi|167000400 gamma-aminobutyric acid (GABA) B receptor 1 isoform c
           precursor [Homo sapiens]
          Length = 899

 Score = 30.4 bits (67), Expect = 5.2
 Identities = 20/63 (31%), Positives = 30/63 (47%), Gaps = 9/63 (14%)

Query: 425 PKENPDMEE----FRTMWVIGLGLKKPDN----SEILSIDLTYDIQSFTDTVYRQAVNSK 476
           P+E    +E    +  +W + L L K       S +   D  Y+ Q+ TD +YR A+NS 
Sbjct: 396 PEETGGFQEAPLAYDAIWALALALNKTSGGGGRSGVRLEDFNYNNQTITDQIYR-AMNSS 454

Query: 477 MFE 479
            FE
Sbjct: 455 SFE 457


>gi|11497612 gamma-aminobutyric acid (GABA) B receptor 1 isoform b
           precursor [Homo sapiens]
          Length = 844

 Score = 30.4 bits (67), Expect = 5.2
 Identities = 20/63 (31%), Positives = 30/63 (47%), Gaps = 9/63 (14%)

Query: 425 PKENPDMEE----FRTMWVIGLGLKKPDN----SEILSIDLTYDIQSFTDTVYRQAVNSK 476
           P+E    +E    +  +W + L L K       S +   D  Y+ Q+ TD +YR A+NS 
Sbjct: 341 PEETGGFQEAPLAYDAIWALALALNKTSGGGGRSGVRLEDFNYNNQTITDQIYR-AMNSS 399

Query: 477 MFE 479
            FE
Sbjct: 400 SFE 402


>gi|10835015 gamma-aminobutyric acid (GABA) B receptor 1 isoform a
           precursor [Homo sapiens]
          Length = 961

 Score = 30.4 bits (67), Expect = 5.2
 Identities = 20/63 (31%), Positives = 30/63 (47%), Gaps = 9/63 (14%)

Query: 425 PKENPDMEE----FRTMWVIGLGLKKPDN----SEILSIDLTYDIQSFTDTVYRQAVNSK 476
           P+E    +E    +  +W + L L K       S +   D  Y+ Q+ TD +YR A+NS 
Sbjct: 458 PEETGGFQEAPLAYDAIWALALALNKTSGGGGRSGVRLEDFNYNNQTITDQIYR-AMNSS 516

Query: 477 MFE 479
            FE
Sbjct: 517 SFE 519


>gi|39812378 RAN binding protein 9 [Homo sapiens]
          Length = 729

 Score = 30.4 bits (67), Expect = 5.2
 Identities = 41/141 (29%), Positives = 53/141 (37%), Gaps = 28/141 (19%)

Query: 3   PFPVTTQGPPQPAPPPNRYGVSSPIS--------LAVPKETDCLLTQRLI---ETLRPF- 50
           P P T   PP P PPP     ++P S         A P       T  L+       PF 
Sbjct: 75  PPPATAAPPPPPPPPPPPASAAAPASGPPAPPGLAAGPGPAGGAPTPALVAGSSAAAPFP 134

Query: 51  ----GVFEEEEELQRRILVLEKLNNLVKEWIREISESKSLPQSVIENVGGKIFTFGSYRL 106
                + E+E+ELQRR   L++L   V E    +  S S P+     +G          L
Sbjct: 135 HGDSALNEQEKELQRR---LKRLYPAVDEQETPLPRSWS-PKDKFSYIG-----LSQNNL 185

Query: 107 GVHTKG---ADIDALCVAPSH 124
            VH KG      DA  V  +H
Sbjct: 186 RVHYKGHGKTPKDAASVRATH 206


>gi|223468681 v-rel reticuloendotheliosis viral oncogene homolog A
           isoform 2 [Homo sapiens]
          Length = 548

 Score = 30.0 bits (66), Expect = 6.8
 Identities = 13/24 (54%), Positives = 14/24 (58%)

Query: 10  GPPQPAPPPNRYGVSSPISLAVPK 33
           GP  P PPP R  V S  S +VPK
Sbjct: 317 GPTDPRPPPRRIAVPSRSSASVPK 340


>gi|223468676 v-rel reticuloendotheliosis viral oncogene homolog A
           isoform 1 [Homo sapiens]
          Length = 551

 Score = 30.0 bits (66), Expect = 6.8
 Identities = 13/24 (54%), Positives = 14/24 (58%)

Query: 10  GPPQPAPPPNRYGVSSPISLAVPK 33
           GP  P PPP R  V S  S +VPK
Sbjct: 320 GPTDPRPPPRRIAVPSRSSASVPK 343


>gi|120587025 SH3 and multiple ankyrin repeat domains 1 [Homo sapiens]
          Length = 2161

 Score = 30.0 bits (66), Expect = 6.8
 Identities = 27/106 (25%), Positives = 49/106 (46%), Gaps = 6/106 (5%)

Query: 506  KKAHSTEGRRLTDLNDSSF---DLSAGCENSMSVPSSTSTMKTG--PLISSSQGRNSPAL 560
            ++  S + +RL+D + SS     +S+  +N    P       TG  P  +++ G  SP+ 
Sbjct: 1914 ERTSSLQRQRLSDDSQSSLLSKPVSSLFQNWPKPPLPPLPTGTGVSPTAAAAPGATSPSA 1973

Query: 561  AVMTASVANIQATEFSLQQVNTNESSGVALNESIPHAVSQPAISPS 606
            +  + S  ++Q  EF ++      +   +L  +  H VS PA  PS
Sbjct: 1974 SSSSTSTRHLQGVEFEMRPPLLRRAPSPSLLPASEHKVS-PAPRPS 2018


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.319    0.134    0.393 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 24,521,542
Number of Sequences: 37866
Number of extensions: 1114775
Number of successful extensions: 5601
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 5
Number of HSP's successfully gapped in prelim test: 28
Number of HSP's that attempted gapping in prelim test: 5573
Number of HSP's gapped (non-prelim): 54
length of query: 637
length of database: 18,247,518
effective HSP length: 109
effective length of query: 528
effective length of database: 14,120,124
effective search space: 7455425472
effective search space used: 7455425472
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 65 (29.6 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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