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Search of human proteins with 7706735
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|7706735 TFIIA alpha, p55 isoform 1 [Homo sapiens]
(376 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|7706735 TFIIA alpha, p55 isoform 1 [Homo sapiens] 751 0.0
gi|42476101 TFIIA alpha, p55 isoform 2 [Homo sapiens] 676 0.0
gi|29553944 STON1-GTF2A1L protein [Homo sapiens] 135 8e-32
gi|26787968 general transcription factor IIA, 1-like isoform 1 [... 135 8e-32
gi|26787966 general transcription factor IIA, 1-like isoform 2 [... 89 6e-18
gi|221139761 zinc finger protein 853 [Homo sapiens] 60 3e-09
gi|56549696 E1A binding protein p400 [Homo sapiens] 54 3e-07
gi|155030232 proline, glutamic acid and leucine rich protein 1 [... 53 4e-07
gi|166064029 angiomotin isoform 1 [Homo sapiens] 53 4e-07
gi|17975763 myelin transcription factor 1 [Homo sapiens] 53 5e-07
gi|60498973 myelin transcription factor 1-like [Homo sapiens] 53 5e-07
gi|20336260 retinoblastoma protein-binding zinc finger protein i... 52 7e-07
gi|20336258 retinoblastoma protein-binding zinc finger protein i... 52 7e-07
gi|55953110 retinoblastoma protein-binding zinc finger protein i... 52 9e-07
gi|56549668 AT rich interactive domain 2 (ARID, RFX-like) [Homo ... 52 1e-06
gi|149999352 forkhead box P2 isoform II [Homo sapiens] 51 1e-06
gi|21312134 mediator complex subunit 15 isoform b [Homo sapiens] 51 1e-06
gi|4507379 TATA box binding protein [Homo sapiens] 50 3e-06
gi|38787935 BMP-2 inducible kinase isoform a [Homo sapiens] 50 4e-06
gi|38787904 BMP-2 inducible kinase isoform b [Homo sapiens] 50 4e-06
gi|51477700 mediator complex subunit 15 isoform a [Homo sapiens] 50 4e-06
gi|17017963 forkhead box P2 isoform I [Homo sapiens] 49 7e-06
gi|22538413 forkhead box P2 isoform III [Homo sapiens] 49 7e-06
gi|55956788 nucleolin [Homo sapiens] 49 7e-06
gi|61676188 HECT, UBA and WWE domain containing 1 [Homo sapiens] 49 7e-06
gi|21735415 centromere protein B [Homo sapiens] 48 1e-05
gi|156071452 nardilysin isoform b [Homo sapiens] 48 1e-05
gi|156071450 nardilysin isoform a [Homo sapiens] 48 1e-05
gi|62953127 polyhomeotic 1-like [Homo sapiens] 48 1e-05
gi|157743257 POU domain, class 6, transcription factor 2 [Homo s... 47 2e-05
>gi|7706735 TFIIA alpha, p55 isoform 1 [Homo sapiens]
Length = 376
Score = 751 bits (1938), Expect = 0.0
Identities = 376/376 (100%), Positives = 376/376 (100%)
Query: 1 MANSANTNTVPKLYRSVIEDVINDVRDIFLDDGVDEQVLMELKTLWENKLMQSRAVDGFH 60
MANSANTNTVPKLYRSVIEDVINDVRDIFLDDGVDEQVLMELKTLWENKLMQSRAVDGFH
Sbjct: 1 MANSANTNTVPKLYRSVIEDVINDVRDIFLDDGVDEQVLMELKTLWENKLMQSRAVDGFH 60
Query: 61 SEEQQLLLQVQQQHQPQQQQHHHHHHHQQAQPQQTVPQQAQTQQVLIPASQQATAPQVIV 120
SEEQQLLLQVQQQHQPQQQQHHHHHHHQQAQPQQTVPQQAQTQQVLIPASQQATAPQVIV
Sbjct: 61 SEEQQLLLQVQQQHQPQQQQHHHHHHHQQAQPQQTVPQQAQTQQVLIPASQQATAPQVIV 120
Query: 121 PDSKLIQHMNASNMSAAATAATLALPAGVTPVQQILTNSGQLLQVVRAANGAQYIFQPQQ 180
PDSKLIQHMNASNMSAAATAATLALPAGVTPVQQILTNSGQLLQVVRAANGAQYIFQPQQ
Sbjct: 121 PDSKLIQHMNASNMSAAATAATLALPAGVTPVQQILTNSGQLLQVVRAANGAQYIFQPQQ 180
Query: 181 SVVLQQQVIPQMQPGGVQAPVIQQVLAPLPGGISPQTGVIIQPQQILFTGNKTQVIPTTV 240
SVVLQQQVIPQMQPGGVQAPVIQQVLAPLPGGISPQTGVIIQPQQILFTGNKTQVIPTTV
Sbjct: 181 SVVLQQQVIPQMQPGGVQAPVIQQVLAPLPGGISPQTGVIIQPQQILFTGNKTQVIPTTV 240
Query: 241 AAPTPAQAQITATGQQQPQAQPAQTQAPLVLQVDGTGDTSSEEDEDEEEDYDDDEEEDKE 300
AAPTPAQAQITATGQQQPQAQPAQTQAPLVLQVDGTGDTSSEEDEDEEEDYDDDEEEDKE
Sbjct: 241 AAPTPAQAQITATGQQQPQAQPAQTQAPLVLQVDGTGDTSSEEDEDEEEDYDDDEEEDKE 300
Query: 301 KDGAEDGQVEEEPLNSEDDVSDEEGQELFDTENVVVCQYDKIHRSKNKWKFHLKDGIMNL 360
KDGAEDGQVEEEPLNSEDDVSDEEGQELFDTENVVVCQYDKIHRSKNKWKFHLKDGIMNL
Sbjct: 301 KDGAEDGQVEEEPLNSEDDVSDEEGQELFDTENVVVCQYDKIHRSKNKWKFHLKDGIMNL 360
Query: 361 NGRDYIFSKAIGDAEW 376
NGRDYIFSKAIGDAEW
Sbjct: 361 NGRDYIFSKAIGDAEW 376
>gi|42476101 TFIIA alpha, p55 isoform 2 [Homo sapiens]
Length = 337
Score = 676 bits (1743), Expect = 0.0
Identities = 337/337 (100%), Positives = 337/337 (100%)
Query: 40 MELKTLWENKLMQSRAVDGFHSEEQQLLLQVQQQHQPQQQQHHHHHHHQQAQPQQTVPQQ 99
MELKTLWENKLMQSRAVDGFHSEEQQLLLQVQQQHQPQQQQHHHHHHHQQAQPQQTVPQQ
Sbjct: 1 MELKTLWENKLMQSRAVDGFHSEEQQLLLQVQQQHQPQQQQHHHHHHHQQAQPQQTVPQQ 60
Query: 100 AQTQQVLIPASQQATAPQVIVPDSKLIQHMNASNMSAAATAATLALPAGVTPVQQILTNS 159
AQTQQVLIPASQQATAPQVIVPDSKLIQHMNASNMSAAATAATLALPAGVTPVQQILTNS
Sbjct: 61 AQTQQVLIPASQQATAPQVIVPDSKLIQHMNASNMSAAATAATLALPAGVTPVQQILTNS 120
Query: 160 GQLLQVVRAANGAQYIFQPQQSVVLQQQVIPQMQPGGVQAPVIQQVLAPLPGGISPQTGV 219
GQLLQVVRAANGAQYIFQPQQSVVLQQQVIPQMQPGGVQAPVIQQVLAPLPGGISPQTGV
Sbjct: 121 GQLLQVVRAANGAQYIFQPQQSVVLQQQVIPQMQPGGVQAPVIQQVLAPLPGGISPQTGV 180
Query: 220 IIQPQQILFTGNKTQVIPTTVAAPTPAQAQITATGQQQPQAQPAQTQAPLVLQVDGTGDT 279
IIQPQQILFTGNKTQVIPTTVAAPTPAQAQITATGQQQPQAQPAQTQAPLVLQVDGTGDT
Sbjct: 181 IIQPQQILFTGNKTQVIPTTVAAPTPAQAQITATGQQQPQAQPAQTQAPLVLQVDGTGDT 240
Query: 280 SSEEDEDEEEDYDDDEEEDKEKDGAEDGQVEEEPLNSEDDVSDEEGQELFDTENVVVCQY 339
SSEEDEDEEEDYDDDEEEDKEKDGAEDGQVEEEPLNSEDDVSDEEGQELFDTENVVVCQY
Sbjct: 241 SSEEDEDEEEDYDDDEEEDKEKDGAEDGQVEEEPLNSEDDVSDEEGQELFDTENVVVCQY 300
Query: 340 DKIHRSKNKWKFHLKDGIMNLNGRDYIFSKAIGDAEW 376
DKIHRSKNKWKFHLKDGIMNLNGRDYIFSKAIGDAEW
Sbjct: 301 DKIHRSKNKWKFHLKDGIMNLNGRDYIFSKAIGDAEW 337
>gi|29553944 STON1-GTF2A1L protein [Homo sapiens]
Length = 1182
Score = 135 bits (339), Expect = 8e-32
Identities = 68/133 (51%), Positives = 87/133 (65%), Gaps = 26/133 (19%)
Query: 270 VLQVDGTGDTSSEEDEDEEEDYDDDE-------------EEDKEKDGAEDGQ-------- 308
++QVDG+GDTSS E+ D D++E EE+ + ED
Sbjct: 1050 IIQVDGSGDTSSNEEIGSTRDADENEFLGNIDGGDLKVPEEEADSISNEDSATNSSDNED 1109
Query: 309 -----VEEEPLNSEDDVSDEEGQELFDTENVVVCQYDKIHRSKNKWKFHLKDGIMNLNGR 363
VEE+PLNS DDVS+++ +LFDT+NV+VCQYDKIHRSKNKWKF+LKDG+M GR
Sbjct: 1110 PQVNIVEEDPLNSGDDVSEQDVPDLFDTDNVIVCQYDKIHRSKNKWKFYLKDGVMCFGGR 1169
Query: 364 DYIFSKAIGDAEW 376
DY+F+KAIGDAEW
Sbjct: 1170 DYVFAKAIGDAEW 1182
Score = 86.7 bits (213), Expect = 3e-17
Identities = 91/290 (31%), Positives = 129/290 (44%), Gaps = 56/290 (19%)
Query: 8 NTVPKLYRSVIEDVINDVRDIFLDDGVDEQVLMELKTLWENKLMQSRAV-DGFHSEEQQL 66
N PKLYRSVIEDVI VR++F ++G++EQVL +LK LWE K++QS+A D F + Q
Sbjct: 709 NIQPKLYRSVIEDVIEGVRNLFAEEGIEEQVLKDLKQLWETKVLQSKATEDFFRNSIQSP 768
Query: 67 LLQVQQQHQPQQQQHHHHHHHQQAQPQQTVPQQAQTQQVLIPASQQATAPQVIVPDSKLI 126
L +Q H Q Q+ T ++IPA + T P +
Sbjct: 769 LFTLQLPHSLHQ------------------TLQSSTASLVIPAGR--TLPSFTTAE---- 804
Query: 127 QHMNASNMSAAAT--AATLALPAGVTPVQQILTNSGQLLQV-----VRAANGAQYIFQ-P 178
+ SN SA T + +PAGVT + T SG L +V V +G I Q P
Sbjct: 805 --LGTSNSSANFTFPGYPIHVPAGVT----LQTVSGHLYKVNVPIMVTETSGRAGILQHP 858
Query: 179 QQSVVLQ-------QQVIPQMQPGGVQAPV-----IQQVL---APLPGGISPQTGVIIQP 223
Q V Q Q +PQ+ P +QA I+ VL A LP G + +
Sbjct: 859 IQQVFQQLGQPSVIQTSVPQLNPWSLQATTEKSQRIETVLQQPAILPSGPVDRKHLENAT 918
Query: 224 QQILFT-GNKTQVIPTTVAAPTPAQAQITATGQQ-QPQAQPAQTQAPLVL 271
IL + GN+ +++P + + I+ G PQ + VL
Sbjct: 919 SDILVSPGNEHKIVPEALLCHQESSHYISLPGVVFSPQVSQTNSNVESVL 968
>gi|26787968 general transcription factor IIA, 1-like isoform 1
[Homo sapiens]
Length = 478
Score = 135 bits (339), Expect = 8e-32
Identities = 68/133 (51%), Positives = 87/133 (65%), Gaps = 26/133 (19%)
Query: 270 VLQVDGTGDTSSEEDEDEEEDYDDDE-------------EEDKEKDGAEDGQ-------- 308
++QVDG+GDTSS E+ D D++E EE+ + ED
Sbjct: 346 IIQVDGSGDTSSNEEIGSTRDADENEFLGNIDGGDLKVPEEEADSISNEDSATNSSDNED 405
Query: 309 -----VEEEPLNSEDDVSDEEGQELFDTENVVVCQYDKIHRSKNKWKFHLKDGIMNLNGR 363
VEE+PLNS DDVS+++ +LFDT+NV+VCQYDKIHRSKNKWKF+LKDG+M GR
Sbjct: 406 PQVNIVEEDPLNSGDDVSEQDVPDLFDTDNVIVCQYDKIHRSKNKWKFYLKDGVMCFGGR 465
Query: 364 DYIFSKAIGDAEW 376
DY+F+KAIGDAEW
Sbjct: 466 DYVFAKAIGDAEW 478
Score = 89.0 bits (219), Expect = 6e-18
Identities = 92/290 (31%), Positives = 130/290 (44%), Gaps = 56/290 (19%)
Query: 8 NTVPKLYRSVIEDVINDVRDIFLDDGVDEQVLMELKTLWENKLMQSRAV-DGFHSEEQQL 66
N VPKLYRSVIEDVI VR++F ++G++EQVL +LK LWE K++QS+A D F + Q
Sbjct: 5 NPVPKLYRSVIEDVIEGVRNLFAEEGIEEQVLKDLKQLWETKVLQSKATEDFFRNSIQSP 64
Query: 67 LLQVQQQHQPQQQQHHHHHHHQQAQPQQTVPQQAQTQQVLIPASQQATAPQVIVPDSKLI 126
L +Q H Q Q+ T ++IPA + T P +
Sbjct: 65 LFTLQLPHSLHQ------------------TLQSSTASLVIPAGR--TLPSFTTAE---- 100
Query: 127 QHMNASNMSAAAT--AATLALPAGVTPVQQILTNSGQLLQV-----VRAANGAQYIFQ-P 178
+ SN SA T + +PAGVT + T SG L +V V +G I Q P
Sbjct: 101 --LGTSNSSANFTFPGYPIHVPAGVT----LQTVSGHLYKVNVPIMVTETSGRAGILQHP 154
Query: 179 QQSVVLQ-------QQVIPQMQPGGVQAPV-----IQQVL---APLPGGISPQTGVIIQP 223
Q V Q Q +PQ+ P +QA I+ VL A LP G + +
Sbjct: 155 IQQVFQQLGQPSVIQTSVPQLNPWSLQATTEKSQRIETVLQQPAILPSGPVDRKHLENAT 214
Query: 224 QQILFT-GNKTQVIPTTVAAPTPAQAQITATGQQ-QPQAQPAQTQAPLVL 271
IL + GN+ +++P + + I+ G PQ + VL
Sbjct: 215 SDILVSPGNEHKIVPEALLCHQESSHYISLPGVVFSPQVSQTNSNVESVL 264
>gi|26787966 general transcription factor IIA, 1-like isoform 2
[Homo sapiens]
Length = 453
Score = 89.0 bits (219), Expect = 6e-18
Identities = 92/290 (31%), Positives = 130/290 (44%), Gaps = 56/290 (19%)
Query: 8 NTVPKLYRSVIEDVINDVRDIFLDDGVDEQVLMELKTLWENKLMQSRAV-DGFHSEEQQL 66
N VPKLYRSVIEDVI VR++F ++G++EQVL +LK LWE K++QS+A D F + Q
Sbjct: 5 NPVPKLYRSVIEDVIEGVRNLFAEEGIEEQVLKDLKQLWETKVLQSKATEDFFRNSIQSP 64
Query: 67 LLQVQQQHQPQQQQHHHHHHHQQAQPQQTVPQQAQTQQVLIPASQQATAPQVIVPDSKLI 126
L +Q H Q Q+ T ++IPA + T P +
Sbjct: 65 LFTLQLPHSLHQ------------------TLQSSTASLVIPAGR--TLPSFTTAE---- 100
Query: 127 QHMNASNMSAAAT--AATLALPAGVTPVQQILTNSGQLLQV-----VRAANGAQYIFQ-P 178
+ SN SA T + +PAGVT + T SG L +V V +G I Q P
Sbjct: 101 --LGTSNSSANFTFPGYPIHVPAGVT----LQTVSGHLYKVNVPIMVTETSGRAGILQHP 154
Query: 179 QQSVVLQ-------QQVIPQMQPGGVQAPV-----IQQVL---APLPGGISPQTGVIIQP 223
Q V Q Q +PQ+ P +QA I+ VL A LP G + +
Sbjct: 155 IQQVFQQLGQPSVIQTSVPQLNPWSLQATTEKSQRIETVLQQPAILPSGPVDRKHLENAT 214
Query: 224 QQILFT-GNKTQVIPTTVAAPTPAQAQITATGQQ-QPQAQPAQTQAPLVL 271
IL + GN+ +++P + + I+ G PQ + VL
Sbjct: 215 SDILVSPGNEHKIVPEALLCHQESSHYISLPGVVFSPQVSQTNSNVESVL 264
Score = 71.2 bits (173), Expect = 1e-12
Identities = 40/98 (40%), Positives = 55/98 (56%), Gaps = 26/98 (26%)
Query: 270 VLQVDGTGDTSSEEDEDEEEDYDDDE-------------EEDKEKDGAEDGQ-------- 308
++QVDG+GDTSS E+ D D++E EE+ + ED
Sbjct: 346 IIQVDGSGDTSSNEEIGSTRDADENEFLGNIDGGDLKVPEEEADSISNEDSATNSSDNED 405
Query: 309 -----VEEEPLNSEDDVSDEEGQELFDTENVVVCQYDK 341
VEE+PLNS DDVS+++ +LFDT+NV+VCQYDK
Sbjct: 406 PQVNIVEEDPLNSGDDVSEQDVPDLFDTDNVIVCQYDK 443
>gi|221139761 zinc finger protein 853 [Homo sapiens]
Length = 659
Score = 60.1 bits (144), Expect = 3e-09
Identities = 73/292 (25%), Positives = 115/292 (39%), Gaps = 49/292 (16%)
Query: 63 EQQLLLQVQQQHQPQQQQHHHHHHHQQAQP--------QQTVPQQAQTQQVLIP-----A 109
+QQ QQQ QQ+ H HHQ+ +P QQ PQQ Q QQ L
Sbjct: 119 QQQPQQDGQQQLSQLQQEKHQSVHHQELKPELQLMHQQQQLQPQQVQEQQRLQQQQEQLQ 178
Query: 110 SQQATAPQVIVPDSKLIQHMNASNMSAAATAATLALPAGVTPVQQILTNSGQLLQVVRAA 169
+QQA QV+ +L Q + + L QQ+L QL Q
Sbjct: 179 TQQAQEQQVLQQQEQLQQQVQEQQL--------LQQQQEQLQQQQLLQQQEQLQQ----- 225
Query: 170 NGAQYIFQPQQSVVLQQQVIPQMQPGGVQAPVIQQVLAPLPGGISPQTGVIIQPQQILFT 229
Q Q Q+ + QQQ++ Q G +Q ++QQ A L + Q +Q Q +L
Sbjct: 226 ---QQFQQQQEQLQQQQQLLLLQQQGQLQQQLLQQQQAQLQQQLLEQQQAQLQQQLLLQQ 282
Query: 230 GNKTQVIPTTVAAPTPAQAQITATGQQQPQAQPAQTQAP---------LVLQVDGTGDTS 280
+ Q Q Q QQQ Q Q Q Q P + L++ S
Sbjct: 283 QEQLQ-----------QQQQQQLLQQQQEQLQQQQLQPPPLEPEEEEEVELELMPVDLGS 331
Query: 281 SEEDEDEEEDYDDDEEEDKEKDGAEDGQVEEEPLNSEDDVSDEEGQELFDTE 332
+E E + ++ + +E +++++ + +E L + +++ Q+L E
Sbjct: 332 EQELEQQRQELERQQELERQQEQRQLQLKLQEELQQLEQQLEQQQQQLEQQE 383
Score = 50.8 bits (120), Expect = 2e-06
Identities = 69/271 (25%), Positives = 103/271 (38%), Gaps = 17/271 (6%)
Query: 68 LQVQQ-QHQPQQQQHHHHHHHQQAQPQ---QTVPQQAQTQQV--LIPASQQATAPQVIVP 121
LQ+QQ + QP+ QQ H QQ QP Q PQQ QQ+ L Q+ Q + P
Sbjct: 89 LQLQQLEQQPEPQQQPQHEQLQQPQPHLELQQQPQQDGQQQLSQLQQEKHQSVHHQELKP 148
Query: 122 DSKLIQHMNASNMSAAATAATLALPAGVTPVQQILTNSGQLLQVVRAANGAQYIFQPQQS 181
+ +L+ L +Q+ T Q QV++ Q Q QQ
Sbjct: 149 ELQLMHQQQQLQPQQVQEQQRLQ-----QQQEQLQTQQAQEQQVLQQQEQLQQQVQEQQL 203
Query: 182 VVLQQQVIPQMQPGGVQAPVIQQVLAPLPGGISPQTGVII-----QPQQILFTGNKTQVI 236
+ QQ+ + Q Q Q + QQ + Q +++ Q QQ L + Q +
Sbjct: 204 LQQQQEQLQQQQLLQQQEQLQQQQFQQQQEQLQQQQQLLLLQQQGQLQQQLLQQQQAQ-L 262
Query: 237 PTTVAAPTPAQAQITATGQQQPQAQPAQTQAPLVLQVDGTGDTSSEEDEDEEEDYDDDEE 296
+ AQ Q QQQ Q Q Q Q L Q + + E E+ ++ E
Sbjct: 263 QQQLLEQQQAQLQQQLLLQQQEQLQQQQQQQLLQQQQEQLQQQQLQPPPLEPEEEEEVEL 322
Query: 297 EDKEKDGAEDGQVEEEPLNSEDDVSDEEGQE 327
E D + ++E++ E E QE
Sbjct: 323 ELMPVDLGSEQELEQQRQELERQQELERQQE 353
Score = 37.7 bits (86), Expect = 0.017
Identities = 41/156 (26%), Positives = 58/156 (37%), Gaps = 30/156 (19%)
Query: 35 DEQVLMELKTLWENKLMQSRAVDGFHSEEQQLLLQVQQQHQPQQQQHHHHHHHQQAQPQQ 94
++QVL + + L + Q +QQ LLQ Q+Q Q QQQ QQ Q
Sbjct: 184 EQQVLQQQEQLQQQVQEQQLLQQQQEQLQQQQLLQQQEQLQ-QQQFQQQQEQLQQQQQLL 242
Query: 95 TVPQQAQTQQVLIPASQQATAPQVIVPDSKLIQHMNASNMSAAATAATLALPAGVTPVQQ 154
+ QQ Q QQ L+ Q Q++ +Q QQ
Sbjct: 243 LLQQQGQLQQQLLQQQQAQLQQQLLEQQQAQLQ-------------------------QQ 277
Query: 155 ILTNSGQLLQVVRAANGAQYIFQPQQSVVLQQQVIP 190
+L + LQ Q + Q QQ + QQQ+ P
Sbjct: 278 LLLQQQEQLQ----QQQQQQLLQQQQEQLQQQQLQP 309
Score = 33.5 bits (75), Expect = 0.32
Identities = 50/234 (21%), Positives = 88/234 (37%), Gaps = 30/234 (12%)
Query: 34 VDEQVLMELKTLWENKLMQSRAVDGFHSEEQQLLLQVQQQHQPQQQQHHHHHHHQQAQPQ 93
+ +Q+L + + + +L+ + ++QQLL Q Q+Q Q QQ Q ++ + +
Sbjct: 262 LQQQLLEQQQAQLQQQLLLQQQEQLQQQQQQQLLQQQQEQLQQQQLQPPPLEPEEEEEVE 321
Query: 94 -QTVPQQAQTQQVLIPASQQATAPQVIVPDSKLIQHMNASNMSAAATAATLALPAGVTPV 152
+ +P ++Q L Q+ Q +L + + L +
Sbjct: 322 LELMPVDLGSEQELEQQRQELERQQ------ELERQQEQRQLQLKLQEELQQLEQQLEQQ 375
Query: 153 QQILTNSGQLLQVVRAANGAQYIFQPQQSV---------VLQQQVIPQMQPGGVQAPVIQ 203
QQ L L++ GAQ QQ V LQ +++P GG P
Sbjct: 376 QQQLEQQEVQLELTPVELGAQ-----QQEVQLELTPVQPELQLELVPAAGGGGAAVPG-- 428
Query: 204 QVLAPLPGGISPQTGVIIQPQQILFTGNKTQVIPTTVAAPTPAQAQITATGQQQ 257
AP ++P V++Q +L P VA P PA + +Q+
Sbjct: 429 ---APAAVVVAPPGYVVVQELMVL----PAVAAPAVVAIPGPAGSAALTPARQR 475
>gi|56549696 E1A binding protein p400 [Homo sapiens]
Length = 3122
Score = 53.5 bits (127), Expect = 3e-07
Identities = 61/200 (30%), Positives = 78/200 (39%), Gaps = 44/200 (22%)
Query: 67 LLQVQQQHQPQQQQHHHHHHHQQAQPQQTVPQQAQTQQVLIPASQ-QATAPQVIVPDSKL 125
LL+ QQQ Q QQQQ QQ Q QQ Q T QV +P Q QA +P I KL
Sbjct: 2716 LLRQQQQQQQQQQQQQQQQQQQQQQQQQQQQQTTTTSQVQVPQIQGQAQSPAQIKAVGKL 2775
Query: 126 IQHMNASNMSAAATAATLALPAGVTPVQQILTNSGQLLQVVRAANGAQYIFQPQQSVVLQ 185
TP + ++ Q LQ+ Q P Q
Sbjct: 2776 ------------------------TP-EHLIKMQKQKLQMPPQPPPPQAQSAPPQPTA-- 2808
Query: 186 QQVIPQMQPGGVQAPVIQQVLAPLPGGISPQTGVIIQPQQILFTGNKTQVIPTTVAAPTP 245
Q + QP Q+P + V AP PG + TG + Q+ + +PT
Sbjct: 2809 QVQVQTSQPPQQQSPQLTTVTAPRPGAL--LTGTTVANLQVA----RLTRVPT------- 2855
Query: 246 AQAQITATGQQQPQA-QPAQ 264
+Q+ A GQ Q QA QPAQ
Sbjct: 2856 --SQLQAQGQMQTQAPQPAQ 2873
Score = 38.5 bits (88), Expect = 0.010
Identities = 58/220 (26%), Positives = 79/220 (35%), Gaps = 46/220 (20%)
Query: 65 QLLLQVQQQHQPQQQQHHHHHHHQQAQPQQTVPQQAQTQQVLIPASQQATAPQVIVPDSK 124
Q LL+++QQ QQ+ Q AQ V Q+ QQ+ P +QQ
Sbjct: 2927 QQLLKLKQQAVQQQKAIQP----QAAQGPAAVQQKITAQQITTPGAQQKV---------- 2972
Query: 125 LIQHMNASNMSAAATAATLALPAGVTPVQQILTNSGQLLQVVRAANGAQYIFQPQQSVVL 184
A A L TP+ Q + GAQ + Q Q V
Sbjct: 2973 -----------AYAAQPALKTQFLTTPISQ-----------AQKLAGAQQV-QTQIQVAK 3009
Query: 185 QQQVIPQMQPGGVQAPVIQQVLAPLPGGISPQTGVIIQPQQILFTGNKTQVIPTTVAAPT 244
QV+ Q P IQQV A SPQT + Q G + Q+IP A
Sbjct: 3010 LPQVVQQQTP----VASIQQV-ASASQQASPQTVALTQATA---AGQQVQMIPAVTATAQ 3061
Query: 245 PAQAQITATGQQQPQAQPAQTQ-APLVLQVDGTGDTSSEE 283
Q ++ + P QT AP QV + D+ S++
Sbjct: 3062 VVQQKLIQQQVVTTASAPLQTPGAPNPAQVPASSDSPSQQ 3101
>gi|155030232 proline, glutamic acid and leucine rich protein 1
[Homo sapiens]
Length = 1130
Score = 53.1 bits (126), Expect = 4e-07
Identities = 41/158 (25%), Positives = 73/158 (46%), Gaps = 12/158 (7%)
Query: 181 SVVLQQQVIPQMQPGGVQAPVIQQVLAPLPGGISPQTGVIIQPQQILFTGNKTQVIPTTV 240
SVV+ + +P + P + P SP +P+++ +P
Sbjct: 787 SVVIVPEGLPPLPPPPPSGATPPPIAPTGPPTASPPVPAKEEPEELPAAPGP---LPPPP 843
Query: 241 AAPTPAQAQITATGQQQPQAQPAQTQA---PLVLQVDGTG---DTSSEEDEDEEEDYDDD 294
P P +T PQ P T P L+ D T ++S EE+E+EEE+ +++
Sbjct: 844 PPPPPVPGPVTLP---PPQLVPEGTPGGGGPPALEEDLTVININSSDEEEEEEEEEEEEE 900
Query: 295 EEEDKEKDGAEDGQVEEEPLNSEDDVSDEEGQELFDTE 332
EEE++E++ E+ + +EE E++ +EE +E F+ E
Sbjct: 901 EEEEEEEEDFEEEEEDEEEYFEEEEEEEEEFEEEFEEE 938
Score = 43.1 bits (100), Expect = 4e-04
Identities = 28/98 (28%), Positives = 49/98 (50%), Gaps = 12/98 (12%)
Query: 236 IPTTVAAPTPAQAQITATGQQQPQAQPAQTQAPLVLQVDGTGDTSSEEDEDE-------E 288
+P V P P Q+ G PA + V+ ++ + + EE+E+E E
Sbjct: 849 VPGPVTLPPP---QLVPEGTPGGGGPPALEEDLTVININSSDEEEEEEEEEEEEEEEEEE 905
Query: 289 EDYDDDEEEDKEKDGAEDGQVEEEPLNSEDDVSDEEGQ 326
E+ D +EEE+ E++ E+ + EEE E++ +EEG+
Sbjct: 906 EEEDFEEEEEDEEEYFEEEEEEEEEF--EEEFEEEEGE 941
Score = 41.6 bits (96), Expect = 0.001
Identities = 22/55 (40%), Positives = 38/55 (69%), Gaps = 5/55 (9%)
Query: 282 EEDEDEEEDY----DDDEEEDKEKDGAEDGQVEEEPLNSEDDVSDEEGQELFDTE 332
EE+E++EE+Y +++EEE +E+ E+G++EEE ED+ +EE +E+ D E
Sbjct: 911 EEEEEDEEEYFEEEEEEEEEFEEEFEEEEGELEEEE-EEEDEEEEEELEEVEDLE 964
Score = 30.8 bits (68), Expect = 2.1
Identities = 13/35 (37%), Positives = 23/35 (65%)
Query: 277 GDTSSEEDEDEEEDYDDDEEEDKEKDGAEDGQVEE 311
G+ EE+E++EE+ ++ EE + + G G+VEE
Sbjct: 940 GELEEEEEEEDEEEEEELEEVEDLEFGTAGGEVEE 974
Score = 28.9 bits (63), Expect = 7.9
Identities = 15/46 (32%), Positives = 29/46 (63%), Gaps = 7/46 (15%)
Query: 278 DTSSEEDEDEEEDYDDDE---EEDKEKDGAEDGQVEEEPLNSEDDV 320
+ EE+E+ EE+++++E EE++E++ E EEE L +D+
Sbjct: 922 EEEEEEEEEFEEEFEEEEGELEEEEEEEDEE----EEEELEEVEDL 963
>gi|166064029 angiomotin isoform 1 [Homo sapiens]
Length = 1084
Score = 53.1 bits (126), Expect = 4e-07
Identities = 25/52 (48%), Positives = 31/52 (59%), Gaps = 1/52 (1%)
Query: 70 VQQQHQPQQQQHHHHHHHQQAQPQQTVPQQAQTQQVLIPASQQATAPQVIVP 121
+ QQ Q QQQQHHHHHHHQQ Q QQ Q + + P +Q ++A VP
Sbjct: 374 LSQQQQQQQQQHHHHHHHQQQQQQQPQQQPGEAYSAM-PRAQPSSASYQPVP 424
Score = 37.7 bits (86), Expect = 0.017
Identities = 45/175 (25%), Positives = 60/175 (34%), Gaps = 27/175 (15%)
Query: 108 PASQQATAPQVIVPDSKLIQHMNASNMSAAATAATLALPAGVTPVQQILTNS-------G 160
P + ATA + + + M A+ A A AA A A +P T + G
Sbjct: 886 PVAAAATAAAITATAATITTTMVAAAPVAVAAAAAPAAAAAPSPATAAATAAAVSPAAAG 945
Query: 161 QLLQVVRAANGAQYIFQPQQSVVLQQQVIPQMQPGGVQAPVIQQVLAPLPGGISPQTGVI 220
Q+ A+ A P + QV P APV L P+P + Q
Sbjct: 946 QIPAAASVASAAAVA--PSAAAAAAVQVAP-----AAPAPVPAPALVPVPAPAAAQASAP 998
Query: 221 IQPQQILFTGNKTQVIPTTV--AAPTPAQAQITATGQQQPQAQPAQTQAPLVLQV 273
Q Q PT+ APTPA A Q + A PA P L +
Sbjct: 999 AQTQA-----------PTSAPAVAPTPAPTPTPAVAQAEVPASPATGPGPHRLSI 1042
>gi|17975763 myelin transcription factor 1 [Homo sapiens]
Length = 1121
Score = 52.8 bits (125), Expect = 5e-07
Identities = 26/72 (36%), Positives = 44/72 (61%)
Query: 277 GDTSSEEDEDEEEDYDDDEEEDKEKDGAEDGQVEEEPLNSEDDVSDEEGQELFDTENVVV 336
G S EE+++EEE+ +++EEED+E++ E+ + EEE E++ +EE +E + V+
Sbjct: 253 GILSHEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEAAPDVI 312
Query: 337 CQYDKIHRSKNK 348
Q D H S K
Sbjct: 313 FQEDTSHTSAQK 324
>gi|60498973 myelin transcription factor 1-like [Homo sapiens]
Length = 1184
Score = 52.8 bits (125), Expect = 5e-07
Identities = 32/92 (34%), Positives = 49/92 (53%), Gaps = 13/92 (14%)
Query: 253 TGQQQPQAQPAQTQAPLVLQVD-----------GTGDTSS-EEDEDEEEDYDDDEEEDKE 300
T +QPQ +PA + P ++ D GT D EEDE EE D+DE D++
Sbjct: 63 TQDKQPQ-EPAPKRKPFAVKADSSSVDECDDSDGTEDMDEKEEDEGEEYSEDNDEPGDED 121
Query: 301 KDGAEDGQVEEEPLNSEDDVSDEEGQELFDTE 332
++ E + EEE + ED+ DE+G+++ D E
Sbjct: 122 EEDEEGDREEEEEIEEEDEDDDEDGEDVEDEE 153
Score = 40.4 bits (93), Expect = 0.003
Identities = 21/53 (39%), Positives = 32/53 (60%), Gaps = 1/53 (1%)
Query: 275 GTGDTSSEEDEDEEEDYDDDEEEDKEKDGAEDGQVEEEPLNSEDDVSDEEGQE 327
G D EE + EEE+ ++E+ED ++DG ED + EEE E++ +EE E
Sbjct: 118 GDEDEEDEEGDREEEEEIEEEDEDDDEDG-EDVEDEEEEEEEEEEEEEEEENE 169
Score = 40.4 bits (93), Expect = 0.003
Identities = 21/62 (33%), Positives = 36/62 (58%), Gaps = 3/62 (4%)
Query: 274 DGTGDTSSEED---EDEEEDYDDDEEEDKEKDGAEDGQVEEEPLNSEDDVSDEEGQELFD 330
D GD EE+ EDE++D D ++ ED+E++ E+ + EEE N + ++ + + D
Sbjct: 124 DEEGDREEEEEIEEEDEDDDEDGEDVEDEEEEEEEEEEEEEEEENEDHQMNCHNTRIMQD 183
Query: 331 TE 332
TE
Sbjct: 184 TE 185
Score = 39.3 bits (90), Expect = 0.006
Identities = 25/74 (33%), Positives = 45/74 (60%), Gaps = 5/74 (6%)
Query: 278 DTSSEED-EDEEEDYDDDEE-EDKEKDGAEDGQ-VEEEPLNSEDDVSDEEGQELFDTENV 334
D +ED EDEE D +++EE E++++D EDG+ VE+E E++ +EE +E + ++
Sbjct: 115 DEPGDEDEEDEEGDREEEEEIEEEDEDDDEDGEDVEDEEEEEEEEEEEEEEEE--NEDHQ 172
Query: 335 VVCQYDKIHRSKNK 348
+ C +I + K
Sbjct: 173 MNCHNTRIMQDTEK 186
Score = 35.0 bits (79), Expect = 0.11
Identities = 17/55 (30%), Positives = 30/55 (54%), Gaps = 2/55 (3%)
Query: 274 DGTGDTSSEEDEDEEEDYDDDEEEDKEKDGAEDGQVEEEPLNSEDDVSDEEGQEL 328
D + E+E+E E+ D+D++ED E ED + EEE E++ + E ++
Sbjct: 121 DEEDEEGDREEEEEIEEEDEDDDEDGE--DVEDEEEEEEEEEEEEEEEENEDHQM 173
Score = 34.3 bits (77), Expect = 0.19
Identities = 17/86 (19%), Positives = 42/86 (48%), Gaps = 1/86 (1%)
Query: 254 GQQQPQAQPAQTQAPLVLQVDGTGDTSSEEDEDEEEDYDDDEEEDKEKDGAEDGQVE-EE 312
G + + + + ++ + D ED ++EE+ +++EEE++E++ ED Q+
Sbjct: 118 GDEDEEDEEGDREEEEEIEEEDEDDDEDGEDVEDEEEEEEEEEEEEEEEENEDHQMNCHN 177
Query: 313 PLNSEDDVSDEEGQELFDTENVVVCQ 338
+D D+ + +D + +V +
Sbjct: 178 TRIMQDTEKDDNNNDEYDNYDELVAK 203
Score = 34.3 bits (77), Expect = 0.19
Identities = 16/65 (24%), Positives = 35/65 (53%)
Query: 278 DTSSEEDEDEEEDYDDDEEEDKEKDGAEDGQVEEEPLNSEDDVSDEEGQELFDTENVVVC 337
+ E+D+++ ED +D+EEE++E++ E+ + E+ + + + E D N
Sbjct: 136 EEEDEDDDEDGEDVEDEEEEEEEEEEEEEEEENEDHQMNCHNTRIMQDTEKDDNNNDEYD 195
Query: 338 QYDKI 342
YD++
Sbjct: 196 NYDEL 200
>gi|20336260 retinoblastoma protein-binding zinc finger protein
isoform b [Homo sapiens]
Length = 1682
Score = 52.4 bits (124), Expect = 7e-07
Identities = 33/148 (22%), Positives = 66/148 (44%), Gaps = 12/148 (8%)
Query: 184 LQQQVIPQMQPGGVQAPVIQQVLAPLPGGISPQTGVIIQPQQILFTGNKTQVIPTTVAAP 243
+Q + +P A + P P + QP + + Q +P +A P
Sbjct: 185 IQDIQLKTSEPDFTSANMRDSAEGPKEDEEKPSASALEQPATLQEVAS--QEVPPELATP 242
Query: 244 TPAQAQITATGQQQPQAQPAQTQAPLVLQVDGTGDTSSEEDEDEEEDYDDDEEEDKEKDG 303
PA +PQ +P + +V+ G+ EE+E++EE+ +DD++++ E +G
Sbjct: 243 APAW---------EPQPEPDERLEAAACEVNDLGEEEEEEEEEDEEEEEDDDDDELEDEG 293
Query: 304 AEDGQVEEEPLNSEDDV-SDEEGQELFD 330
E+ + E E ++ DE+ ++L +
Sbjct: 294 EEEASMPNENSVKEPEIRCDEKPEDLLE 321
>gi|20336258 retinoblastoma protein-binding zinc finger protein
isoform a [Homo sapiens]
Length = 1718
Score = 52.4 bits (124), Expect = 7e-07
Identities = 33/148 (22%), Positives = 66/148 (44%), Gaps = 12/148 (8%)
Query: 184 LQQQVIPQMQPGGVQAPVIQQVLAPLPGGISPQTGVIIQPQQILFTGNKTQVIPTTVAAP 243
+Q + +P A + P P + QP + + Q +P +A P
Sbjct: 185 IQDIQLKTSEPDFTSANMRDSAEGPKEDEEKPSASALEQPATLQEVAS--QEVPPELATP 242
Query: 244 TPAQAQITATGQQQPQAQPAQTQAPLVLQVDGTGDTSSEEDEDEEEDYDDDEEEDKEKDG 303
PA +PQ +P + +V+ G+ EE+E++EE+ +DD++++ E +G
Sbjct: 243 APAW---------EPQPEPDERLEAAACEVNDLGEEEEEEEEEDEEEEEDDDDDELEDEG 293
Query: 304 AEDGQVEEEPLNSEDDV-SDEEGQELFD 330
E+ + E E ++ DE+ ++L +
Sbjct: 294 EEEASMPNENSVKEPEIRCDEKPEDLLE 321
>gi|55953110 retinoblastoma protein-binding zinc finger protein
isoform c [Homo sapiens]
Length = 1481
Score = 52.0 bits (123), Expect = 9e-07
Identities = 26/99 (26%), Positives = 53/99 (53%), Gaps = 10/99 (10%)
Query: 233 TQVIPTTVAAPTPAQAQITATGQQQPQAQPAQTQAPLVLQVDGTGDTSSEEDEDEEEDYD 292
+Q +P +A P PA +PQ +P + +V+ G+ EE+E++EE+ +
Sbjct: 31 SQEVPPELATPAPAW---------EPQPEPDERLEAAACEVNDLGEEEEEEEEEDEEEEE 81
Query: 293 DDEEEDKEKDGAEDGQVEEEPLNSEDDV-SDEEGQELFD 330
DD++++ E +G E+ + E E ++ DE+ ++L +
Sbjct: 82 DDDDDELEDEGEEEASMPNENSVKEPEIRCDEKPEDLLE 120
>gi|56549668 AT rich interactive domain 2 (ARID, RFX-like) [Homo
sapiens]
Length = 1835
Score = 51.6 bits (122), Expect = 1e-06
Identities = 78/260 (30%), Positives = 102/260 (39%), Gaps = 33/260 (12%)
Query: 67 LLQVQQQHQPQQQQHHHHHHHQQAQPQQTVPQQAQTQQVLIPASQQATAPQVIVPDSKLI 126
+L V++Q QQQQH QQ Q Q PQQ Q Q + P A Q +S LI
Sbjct: 1006 MLSVKRQ---QQQQHSPAPPPQQVQVQVQQPQQVQMQ--VQPQQSNAGVGQPASGESSLI 1060
Query: 127 QHMNASNMSAAATAATLALPA-GVTPVQQILTNSGQLLQVVRAANGAQYIFQ----PQQS 181
+ + + L LPA + P S Q++ V + A + Q QQ
Sbjct: 1061 KQLLLPKRGPSTPGGKLILPAPQIPPPNNARAPSPQVVYQVASNQAAGFGVQGQTPAQQL 1120
Query: 182 VVLQQ--QVIPQMQP--GGVQAPVIQQVLAPLPGG-ISPQTGVIIQPQQILFTGNKT--Q 234
+V QQ Q++P P GGVQ I L LPG IS I Q +GN+
Sbjct: 1121 LVGQQNVQLVPSAMPPSGGVQTVPISN-LQILPGPLISNSPATIFQGT----SGNQVTIT 1175
Query: 235 VIPTTVAAPTP----------AQAQITATGQQQPQAQPAQTQAPLVLQVDGTGD-TSSEE 283
V+P T AP A A IT +G Q P QT G T++
Sbjct: 1176 VVPNTSFAPATVSQGNATQLIAPAGITMSGTQTGVGLPVQTLPATQASPAGQSSCTTATP 1235
Query: 284 DEDEEEDYDDDEEEDKEKDG 303
++ EEE KE G
Sbjct: 1236 PFKGDKIICQKEEEAKEATG 1255
Score = 36.6 bits (83), Expect = 0.038
Identities = 50/197 (25%), Positives = 69/197 (35%), Gaps = 32/197 (16%)
Query: 95 TVPQQAQTQQVLIPASQQATAPQVIVPD-------SKLIQHMNASNMSAAA----TAATL 143
T PQ QT A Q+ +I P S ++ + N A T A +
Sbjct: 824 TSPQPVQTSSQQTSAGSQSQDTVIIAPPQYVTTSASNIVSATSVQNFQVATGQMVTIAGV 883
Query: 144 ALPAGVTPVQQILTNSGQLLQVVRAANGAQYIFQPQQSVVLQQQVIPQMQP---GGVQAP 200
P Q + Q V + Q I QPQQ QQ V+ QP G AP
Sbjct: 884 PSPQASRVGFQNIAPKPLPSQQVSSTVVQQPIQQPQQPT--QQSVVIVSQPAQQGQTYAP 941
Query: 201 VIQQVL----APLPGGISPQTGVIIQPQQILFTGNKTQVIPTTVAAPTPAQAQITATGQQ 256
I Q++ A LP G Q + TG + + P++ +P PA T
Sbjct: 942 AIHQIVLANPAALPAG-----------QTVQLTG-QPNITPSSSPSPVPATNNQVPTAMS 989
Query: 257 QPQAQPAQTQAPLVLQV 273
+Q P V Q+
Sbjct: 990 SSSTPQSQGPPPTVSQM 1006
>gi|149999352 forkhead box P2 isoform II [Homo sapiens]
Length = 740
Score = 51.2 bits (121), Expect = 1e-06
Identities = 57/199 (28%), Positives = 77/199 (38%), Gaps = 31/199 (15%)
Query: 6 NTNTVPKLYRSVIEDVIN--DVRDIFLDDGVDEQVLMELKTLWENKLMQSRAVDGFHSEE 63
NT VP + VI ++ I + Q L L + ++Q + + F+ ++
Sbjct: 108 NTFAVPVSVAMMTPQVITPQQMQQILQQQVLSPQQLQALLQQQQAVMLQQQQLQEFYKKQ 167
Query: 64 Q-QLLLQVQQQHQPQQQQHHHHHHHQQAQPQQTVPQQAQTQQVLIPASQQATAPQVIVPD 122
Q QL LQ+ QQ Q QQQQ QQ Q QQ QQ Q QQ QQ Q
Sbjct: 168 QEQLHLQLLQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQ------QQQQQQQHPGKQ 221
Query: 123 SKLIQHMNASNMSAAATAATLALPAGVTPVQQILTNSGQLLQVVRAANGAQYIFQPQQSV 182
+K Q AA Q L QLLQ+ Q + Q Q +
Sbjct: 222 AKEQQQQQQQQQQLAA---------------QQLVFQQQLLQM-------QQLQQQQHLL 259
Query: 183 VLQQQVIPQMQPGGVQAPV 201
LQ+Q + + PG PV
Sbjct: 260 SLQRQGLISIPPGQAALPV 278
>gi|21312134 mediator complex subunit 15 isoform b [Homo sapiens]
Length = 748
Score = 51.2 bits (121), Expect = 1e-06
Identities = 61/228 (26%), Positives = 84/228 (36%), Gaps = 20/228 (8%)
Query: 47 ENKLMQSRAVDGFHSEEQQLLLQVQQQHQPQQQQHHH---HHHHQQAQPQQTVPQQAQTQ 103
+ + Q +A ++ Q ++Q QQQ Q QQQQ H HH Q Q QQ Q +
Sbjct: 183 QQQQQQFQAQQSAMQQQFQAVVQQQQQLQQQQQQQQHLIKLHHQNQQQIQQQQQQLQRIA 242
Query: 104 QVLIPASQQATAPQVIVPDSKLIQHMNASNMSAAATAATLALPAGVTPVQQILTNSGQLL 163
Q+ + QQ Q Q + A + P Q L Q L
Sbjct: 243 QLQLQQQQQQQQQQ---------QQQQQQALQAQPPIQQPPMQQPQPPPSQALP---QQL 290
Query: 164 QVVRAANGAQYIFQPQQSVVLQQQVIPQMQPGGVQAPVIQQVLAPLPGGI---SPQTGVI 220
Q + Q QPQQ V Q Q Q+ P P++ Q A LPG + P +
Sbjct: 291 QQMHHTQHHQPPPQPQQPPVAQNQP-SQLPPQSQTQPLVSQAQA-LPGQMLYTQPPLKFV 348
Query: 221 IQPQQILFTGNKTQVIPTTVAAPTPAQAQITATGQQQPQAQPAQTQAP 268
P + + QV A T AQ+ A G Q Q+ +P
Sbjct: 349 RAPMVVQQPPVQPQVQQQQTAVQTAQAAQMVAPGVQVSQSSLPMLSSP 396
Score = 48.5 bits (114), Expect = 1e-05
Identities = 76/308 (24%), Positives = 113/308 (36%), Gaps = 58/308 (18%)
Query: 36 EQVLMELKTLWENKLMQSRAVDGFHSEEQQLLLQVQ--------QQHQP-------QQQQ 80
+Q +L+ + + +L Q + ++QQ LQ Q QQ QP QQ Q
Sbjct: 232 QQQQQQLQRIAQLQLQQQQQQQQQQQQQQQQALQAQPPIQQPPMQQPQPPPSQALPQQLQ 291
Query: 81 HHHHHHHQQAQPQQTVPQQAQTQQVLIPASQQATAPQVIVPDSKLIQHMNASNMSAAATA 140
HH H Q PQ P AQ Q +P Q T P L+ A T
Sbjct: 292 QMHHTQHHQPPPQPQQPPVAQNQPSQLPPQSQ-TQP--------LVSQAQALPGQMLYTQ 342
Query: 141 ATLALPAGVTPVQQ--ILTNSGQLLQVVRAANGAQYIFQPQQSVVLQQQVIPQMQPGGVQ 198
L VQQ + Q V+ A AQ + V + Q +P +
Sbjct: 343 PPLKFVRAPMVVQQPPVQPQVQQQQTAVQTAQAAQMV---APGVQVSQSSLPMLSSPSPG 399
Query: 199 APVIQQVLAPLPGGISPQTG-VIIQPQQILFTG---NKTQVIPTTVAAPTPAQAQITATG 254
V P P SPQ G QP + +G + + +P+ +P P+Q+ +TA
Sbjct: 400 QQVQTPQSMPPPPQPSPQPGQPSSQPNSNVSSGPAPSPSSFLPS--PSPQPSQSPVTA-- 455
Query: 255 QQQPQAQPAQTQAPLVLQVDGTGDTS-SEEDEDEEEDYDD-------------------D 294
+ PQ + PL V+ + S + + EE+ Y D D
Sbjct: 456 -RTPQNFSVPSPGPLNTPVNPSSVMSPAGSSQAEEQQYLDKLKQLSKYIEPLRRMINKID 514
Query: 295 EEEDKEKD 302
+ ED++KD
Sbjct: 515 KNEDRKKD 522
Score = 47.0 bits (110), Expect = 3e-05
Identities = 65/211 (30%), Positives = 78/211 (36%), Gaps = 33/211 (15%)
Query: 65 QLLLQVQQQHQPQQQQHHHHHHHQQAQPQQTVPQQAQTQQVLIPASQQATAP--QVIVPD 122
Q LQ+QQ QQQQ QQA QQ QQ Q QQ A Q A Q +V
Sbjct: 150 QTQLQLQQVALQQQQQQQQFQQQQQAALQQ---QQQQQQQQQFQAQQSAMQQQFQAVVQQ 206
Query: 123 SKLIQHMNASNMSAAATAATLALPAGVTPVQQILTNSGQLLQVVRAANGAQYIFQPQQSV 182
+ +Q + QQI QL ++ + Q Q QQ
Sbjct: 207 QQQLQQQQQQQQH--------LIKLHHQNQQQIQQQQQQLQRIAQLQLQQQQ--QQQQQQ 256
Query: 183 VLQQQVIPQMQPGGVQAPVIQQVLAPLPGGISPQTGVIIQPQQILFTGNKTQVIPTTVAA 242
QQQ Q QP +Q P +QQ P P PQ Q QQ+ T +
Sbjct: 257 QQQQQQALQAQP-PIQQPPMQQPQPP-PSQALPQ-----QLQQMHHTQHH---------- 299
Query: 243 PTPAQAQITATGQQQPQAQPAQTQA-PLVLQ 272
P Q Q Q QP P Q+Q PLV Q
Sbjct: 300 QPPPQPQQPPVAQNQPSQLPPQSQTQPLVSQ 330
>gi|4507379 TATA box binding protein [Homo sapiens]
Length = 339
Score = 50.4 bits (119), Expect = 3e-06
Identities = 37/97 (38%), Positives = 49/97 (50%), Gaps = 3/97 (3%)
Query: 62 EEQQLLLQVQQQHQPQQQQHHHHHHHQQAQPQQTVPQQAQTQQVLIPAS-QQATAPQVIV 120
EEQQ Q QQQ Q QQQQ QQ Q QQ QQ Q QQ + A+ QQ+T+ Q
Sbjct: 53 EEQQRQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQAVAAAAVQQSTSQQATQ 112
Query: 121 PDS-KLIQHMNASNMSAAATAATLAL-PAGVTPVQQI 155
S + Q ++ ++ A T L P+ +TP+ I
Sbjct: 113 GTSGQAPQLFHSQTLTTAPLPGTTPLYPSPMTPMTPI 149
>gi|38787935 BMP-2 inducible kinase isoform a [Homo sapiens]
Length = 1161
Score = 49.7 bits (117), Expect = 4e-06
Identities = 23/43 (53%), Positives = 25/43 (58%)
Query: 62 EEQQLLLQVQQQHQPQQQQHHHHHHHQQAQPQQTVPQQAQTQQ 104
++QQ Q QQQ Q QQQQHHHHHHH Q Q TQQ
Sbjct: 468 QQQQQQQQQQQQQQQQQQQHHHHHHHHLLQDAYMQQYQHATQQ 510
Score = 47.8 bits (112), Expect = 2e-05
Identities = 28/57 (49%), Positives = 32/57 (56%), Gaps = 6/57 (10%)
Query: 62 EEQQLLLQVQQQHQPQQQQHHHHHHH--QQAQPQQ----TVPQQAQTQQVLIPASQQ 112
++QQ Q QQQ Q QQQ HHHHHHH Q A QQ T QQ QQ L+ + Q
Sbjct: 469 QQQQQQQQQQQQQQQQQQHHHHHHHHLLQDAYMQQYQHATQQQQMLQQQFLMHSVYQ 525
Score = 38.9 bits (89), Expect = 0.008
Identities = 38/143 (26%), Positives = 57/143 (39%), Gaps = 20/143 (13%)
Query: 62 EEQQLLLQVQQQHQPQQQQHHHHHHHQQAQPQQTVPQQAQTQQVLIPASQQATA-----P 116
++ ++L Q+QQ QQ H H H Q Q QQ QQ Q QQ QQ
Sbjct: 433 QQHRVLQQLQQGDWRLQQLHLQHRHPHQQQQQQQQQQQQQQQQQQQQQQQQQQQHHHHHH 492
Query: 117 QVIVPDSKLIQHMNASNMSAAATAATLALPAGVTPVQQILTNSGQLLQVVRAANGAQYIF 176
++ D+ + Q+ +A+ QQ L +S + Q +A+ +
Sbjct: 493 HHLLQDAYMQQYQHATQQQQMLQ-------------QQFLMHS--VYQPQPSASQYPTMM 537
Query: 177 QPQQSVVLQQQVIPQMQPGGVQA 199
Q QQQ++ Q QP QA
Sbjct: 538 PQYQQAFFQQQMLAQHQPSQQQA 560
Score = 33.9 bits (76), Expect = 0.25
Identities = 19/76 (25%), Positives = 34/76 (44%)
Query: 257 QPQAQPAQTQAPLVLQVDGTGDTSSEEDEDEEEDYDDDEEEDKEKDGAEDGQVEEEPLNS 316
Q Q Q ++ + D SSEE+E ++E+ E+ D D E + PL
Sbjct: 730 QGQVQKGNDESESDFESDPPSPKSSEEEEQDDEEVLQGEQGDFNDDDTEPENLGHRPLLM 789
Query: 317 EDDVSDEEGQELFDTE 332
+ + +EE + D++
Sbjct: 790 DSEDEEEEEKHSSDSD 805
>gi|38787904 BMP-2 inducible kinase isoform b [Homo sapiens]
Length = 662
Score = 49.7 bits (117), Expect = 4e-06
Identities = 23/43 (53%), Positives = 25/43 (58%)
Query: 62 EEQQLLLQVQQQHQPQQQQHHHHHHHQQAQPQQTVPQQAQTQQ 104
++QQ Q QQQ Q QQQQHHHHHHH Q Q TQQ
Sbjct: 468 QQQQQQQQQQQQQQQQQQQHHHHHHHHLLQDAYMQQYQHATQQ 510
Score = 47.8 bits (112), Expect = 2e-05
Identities = 28/57 (49%), Positives = 32/57 (56%), Gaps = 6/57 (10%)
Query: 62 EEQQLLLQVQQQHQPQQQQHHHHHHH--QQAQPQQ----TVPQQAQTQQVLIPASQQ 112
++QQ Q QQQ Q QQQ HHHHHHH Q A QQ T QQ QQ L+ + Q
Sbjct: 469 QQQQQQQQQQQQQQQQQQHHHHHHHHLLQDAYMQQYQHATQQQQMLQQQFLMHSVYQ 525
Score = 38.9 bits (89), Expect = 0.008
Identities = 38/143 (26%), Positives = 57/143 (39%), Gaps = 20/143 (13%)
Query: 62 EEQQLLLQVQQQHQPQQQQHHHHHHHQQAQPQQTVPQQAQTQQVLIPASQQATA-----P 116
++ ++L Q+QQ QQ H H H Q Q QQ QQ Q QQ QQ
Sbjct: 433 QQHRVLQQLQQGDWRLQQLHLQHRHPHQQQQQQQQQQQQQQQQQQQQQQQQQQQHHHHHH 492
Query: 117 QVIVPDSKLIQHMNASNMSAAATAATLALPAGVTPVQQILTNSGQLLQVVRAANGAQYIF 176
++ D+ + Q+ +A+ QQ L +S + Q +A+ +
Sbjct: 493 HHLLQDAYMQQYQHATQQQQMLQ-------------QQFLMHS--VYQPQPSASQYPTMM 537
Query: 177 QPQQSVVLQQQVIPQMQPGGVQA 199
Q QQQ++ Q QP QA
Sbjct: 538 PQYQQAFFQQQMLAQHQPSQQQA 560
>gi|51477700 mediator complex subunit 15 isoform a [Homo sapiens]
Length = 788
Score = 49.7 bits (117), Expect = 4e-06
Identities = 64/232 (27%), Positives = 86/232 (37%), Gaps = 33/232 (14%)
Query: 47 ENKLMQSRAVDGFHSEEQQLLLQVQQQHQPQQQQHHH---HHHHQQAQPQQTVPQQAQTQ 103
+ + Q +A ++ Q ++Q QQQ Q QQQQ H HH Q Q QQ Q +
Sbjct: 183 QQQQQQFQAQQSAMQQQFQAVVQQQQQLQQQQQQQQHLIKLHHQNQQQIQQQQQQLQRIA 242
Query: 104 QVLIPASQQATAPQVIVPDSKLIQHMNASNMSAAATAATLALPAGVTPVQQILTNSGQLL 163
Q+ + QQ Q Q + A + P Q L Q L
Sbjct: 243 QLQLQQQQQQQQQQ---------QQQQQQALQAQPPIQQPPMQQPQPPPSQALP---QQL 290
Query: 164 QVVRAANGAQYIFQPQQSVVLQQQVIPQMQPGGVQAPVIQQVLAPLPGGISPQTGVIIQP 223
Q + Q QPQQ V Q Q Q+ P P++ Q A LPG
Sbjct: 291 QQMHHTQHHQPPPQPQQPPVAQNQP-SQLPPQSQTQPLVSQAQA-LPG------------ 336
Query: 224 QQILFTGNKTQVI--PTTVAAPTPAQAQITATGQQQPQAQPAQTQAPLVLQV 273
Q+L+T + + P V P P Q Q+ AQ AQ AP V +
Sbjct: 337 -QMLYTQPPLKFVRAPMVVQQP-PVQPQVQQQQTAVQTAQAAQMVAPGVQMI 386
Score = 47.0 bits (110), Expect = 3e-05
Identities = 65/211 (30%), Positives = 78/211 (36%), Gaps = 33/211 (15%)
Query: 65 QLLLQVQQQHQPQQQQHHHHHHHQQAQPQQTVPQQAQTQQVLIPASQQATAP--QVIVPD 122
Q LQ+QQ QQQQ QQA QQ QQ Q QQ A Q A Q +V
Sbjct: 150 QTQLQLQQVALQQQQQQQQFQQQQQAALQQ---QQQQQQQQQFQAQQSAMQQQFQAVVQQ 206
Query: 123 SKLIQHMNASNMSAAATAATLALPAGVTPVQQILTNSGQLLQVVRAANGAQYIFQPQQSV 182
+ +Q + QQI QL ++ + Q Q QQ
Sbjct: 207 QQQLQQQQQQQQH--------LIKLHHQNQQQIQQQQQQLQRIAQLQLQQQQ--QQQQQQ 256
Query: 183 VLQQQVIPQMQPGGVQAPVIQQVLAPLPGGISPQTGVIIQPQQILFTGNKTQVIPTTVAA 242
QQQ Q QP +Q P +QQ P P PQ Q QQ+ T +
Sbjct: 257 QQQQQQALQAQP-PIQQPPMQQPQPP-PSQALPQ-----QLQQMHHTQHH---------- 299
Query: 243 PTPAQAQITATGQQQPQAQPAQTQA-PLVLQ 272
P Q Q Q QP P Q+Q PLV Q
Sbjct: 300 QPPPQPQQPPVAQNQPSQLPPQSQTQPLVSQ 330
Score = 46.2 bits (108), Expect = 5e-05
Identities = 76/337 (22%), Positives = 116/337 (34%), Gaps = 76/337 (22%)
Query: 36 EQVLMELKTLWENKLMQSRAVDGFHSEEQQLLLQVQ--------QQHQP-------QQQQ 80
+Q +L+ + + +L Q + ++QQ LQ Q QQ QP QQ Q
Sbjct: 232 QQQQQQLQRIAQLQLQQQQQQQQQQQQQQQQALQAQPPIQQPPMQQPQPPPSQALPQQLQ 291
Query: 81 HHHHHHHQQAQPQQTVPQQAQTQQVLIPASQQ------------------------ATAP 116
HH H Q PQ P AQ Q +P Q AP
Sbjct: 292 QMHHTQHHQPPPQPQQPPVAQNQPSQLPPQSQTQPLVSQAQALPGQMLYTQPPLKFVRAP 351
Query: 117 QVIVPDSKLIQHMNASNMSAAATAATLALPAGVTPVQQILTNSGQLLQ-------VVRAA 169
V+ Q A AA + P GV + + L G ++ V A
Sbjct: 352 MVVQQPPVQPQVQQQQTAVQTAQAAQMVAP-GVQMITEALAQGGMHIRARFPPTTAVSAI 410
Query: 170 NGAQYIFQPQQSVVLQQQVIPQMQPGGVQAPVIQQVLAPLPGGISPQTG-VIIQPQQILF 228
+ Q + Q +P + V P P SPQ G QP +
Sbjct: 411 PSSSIPLGRQPMAQVSQSSLPMLSSPSPGQQVQTPQSMPPPPQPSPQPGQPSSQPNSNVS 470
Query: 229 TG---NKTQVIPTTVAAPTPAQAQITATGQQQPQAQPAQTQAPLVLQVDGTGDTS-SEED 284
+G + + +P+ +P P+Q+ +TA + PQ + PL V+ + S +
Sbjct: 471 SGPAPSPSSFLPS--PSPQPSQSPVTA---RTPQNFSVPSPGPLNTPVNPSSVMSPAGSS 525
Query: 285 EDEEEDYDD-------------------DEEEDKEKD 302
+ EE+ Y D D+ ED++KD
Sbjct: 526 QAEEQQYLDKLKQLSKYIEPLRRMINKIDKNEDRKKD 562
>gi|17017963 forkhead box P2 isoform I [Homo sapiens]
Length = 715
Score = 48.9 bits (115), Expect = 7e-06
Identities = 46/152 (30%), Positives = 60/152 (39%), Gaps = 28/152 (18%)
Query: 50 LMQSRAVDGFHSEEQQLLLQVQQQHQPQQQQHHHHHHHQQAQPQQTVPQQAQTQQVLIPA 109
L Q + + + +++QL LQ+ QQ Q QQQQ QQ Q QQ QQ Q QQ
Sbjct: 130 LQQQQLQEFYKKQQEQLHLQLLQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQ----- 184
Query: 110 SQQATAPQVIVPDSKLIQHMNASNMSAAATAATLALPAGVTPVQQILTNSGQLLQVVRAA 169
QQ Q +K Q AA Q L QLLQ+
Sbjct: 185 -QQQQQQQHPGKQAKEQQQQQQQQQQLAA---------------QQLVFQQQLLQM---- 224
Query: 170 NGAQYIFQPQQSVVLQQQVIPQMQPGGVQAPV 201
Q + Q Q + LQ+Q + + PG PV
Sbjct: 225 ---QQLQQQQHLLSLQRQGLISIPPGQAALPV 253
Score = 43.5 bits (101), Expect = 3e-04
Identities = 35/127 (27%), Positives = 54/127 (42%), Gaps = 5/127 (3%)
Query: 34 VDEQVLMELKTLWENKLMQSRAVDGFHSEEQQLLLQVQQQHQPQQQQHHHHHHHQQAQPQ 93
+ +Q L E + +L ++QQ Q QQQ Q QQQQ QQ Q Q
Sbjct: 130 LQQQQLQEFYKKQQEQLHLQLLQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQ 189
Query: 94 QTVP-QQAQTQQVLIPASQQATAPQVIVPDS--KLIQHMNASNMSAAATAATLALPAG-- 148
Q P +QA+ QQ QQ A Q++ ++ Q ++ + +++P G
Sbjct: 190 QQHPGKQAKEQQQQQQQQQQLAAQQLVFQQQLLQMQQLQQQQHLLSLQRQGLISIPPGQA 249
Query: 149 VTPVQQI 155
PVQ +
Sbjct: 250 ALPVQSL 256
>gi|22538413 forkhead box P2 isoform III [Homo sapiens]
Length = 623
Score = 48.9 bits (115), Expect = 7e-06
Identities = 46/152 (30%), Positives = 60/152 (39%), Gaps = 28/152 (18%)
Query: 50 LMQSRAVDGFHSEEQQLLLQVQQQHQPQQQQHHHHHHHQQAQPQQTVPQQAQTQQVLIPA 109
L Q + + + +++QL LQ+ QQ Q QQQQ QQ Q QQ QQ Q QQ
Sbjct: 38 LQQQQLQEFYKKQQEQLHLQLLQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQ----- 92
Query: 110 SQQATAPQVIVPDSKLIQHMNASNMSAAATAATLALPAGVTPVQQILTNSGQLLQVVRAA 169
QQ Q +K Q AA Q L QLLQ+
Sbjct: 93 -QQQQQQQHPGKQAKEQQQQQQQQQQLAA---------------QQLVFQQQLLQM---- 132
Query: 170 NGAQYIFQPQQSVVLQQQVIPQMQPGGVQAPV 201
Q + Q Q + LQ+Q + + PG PV
Sbjct: 133 ---QQLQQQQHLLSLQRQGLISIPPGQAALPV 161
Score = 43.5 bits (101), Expect = 3e-04
Identities = 35/127 (27%), Positives = 54/127 (42%), Gaps = 5/127 (3%)
Query: 34 VDEQVLMELKTLWENKLMQSRAVDGFHSEEQQLLLQVQQQHQPQQQQHHHHHHHQQAQPQ 93
+ +Q L E + +L ++QQ Q QQQ Q QQQQ QQ Q Q
Sbjct: 38 LQQQQLQEFYKKQQEQLHLQLLQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQ 97
Query: 94 QTVP-QQAQTQQVLIPASQQATAPQVIVPDS--KLIQHMNASNMSAAATAATLALPAG-- 148
Q P +QA+ QQ QQ A Q++ ++ Q ++ + +++P G
Sbjct: 98 QQHPGKQAKEQQQQQQQQQQLAAQQLVFQQQLLQMQQLQQQQHLLSLQRQGLISIPPGQA 157
Query: 149 VTPVQQI 155
PVQ +
Sbjct: 158 ALPVQSL 164
>gi|55956788 nucleolin [Homo sapiens]
Length = 710
Score = 48.9 bits (115), Expect = 7e-06
Identities = 37/133 (27%), Positives = 60/133 (45%), Gaps = 24/133 (18%)
Query: 219 VIIQPQQ---ILFTGNKTQVIPTTVAAPTPAQAQIT------------ATGQQQPQAQPA 263
V++ P + + K V P AA TPA+ +T AT + A P
Sbjct: 64 VVVSPTKKVAVATPAKKAAVTPGKKAAATPAKKTVTPAKAVTTPGKKGATPGKALVATPG 123
Query: 264 QTQAPLVLQVDGTG------DTSSEEDEDEEEDYDDDEEEDKEKDGAEDGQVE---EEPL 314
+ A + + G D+ EED+D EED +DDE+ED+++D E ++ P
Sbjct: 124 KKGAAIPAKGAKNGKNAKKEDSDEEEDDDSEEDEEDDEDEDEDEDEIEPAAMKAAAAAPA 183
Query: 315 NSEDDVSDEEGQE 327
+ ++D D+E E
Sbjct: 184 SEDEDDEDDEDDE 196
Score = 47.0 bits (110), Expect = 3e-05
Identities = 31/111 (27%), Positives = 56/111 (50%), Gaps = 5/111 (4%)
Query: 255 QQQPQAQPAQ-TQAPLVLQVDGTGDTSSEEDEDEEEDYDDDEEEDKEKDGAEDGQVEEEP 313
++ + PA+ +A V+ V E++E+++ED DDD++ED E D ED + EEE
Sbjct: 208 EEAMETTPAKGKKAAKVVPVKAKNVAEDEDEEEDDEDEDDDDDEDDEDDDDEDDEEEEEE 267
Query: 314 LNSEDDVSDEEG---QELFDTENVVVCQYDKIHRSKNKWKFHLKDGIMNLN 361
E+ V + G +E+ + + K+ ++ F+L G +N N
Sbjct: 268 -EEEEPVKEAPGKRKKEMAKQKAAPEAKKQKVEGTEPTTAFNLFVGNLNFN 317
Score = 40.4 bits (93), Expect = 0.003
Identities = 31/142 (21%), Positives = 55/142 (38%), Gaps = 5/142 (3%)
Query: 188 VIPQMQPGGVQAPVIQQVLAPLPGGISPQTGVIIQPQQILFTGNKTQVIPTTVAAPTPAQ 247
V+ + V P + + P + + P + + T K P TP +
Sbjct: 65 VVSPTKKVAVATPAKKAAVTPGKKAAATPAKKTVTPAKAVTTPGKKGATPGKALVATPGK 124
Query: 248 --AQITATGQQQPQAQPAQTQAPLVLQVDGTGDTSSEEDEDEEEDYDDDEEEDKEKDGAE 305
A I A G + + + + D + E+DEDE+ED D+ E + A
Sbjct: 125 KGAAIPAKGAKNGKNAKKEDSDE---EEDDDSEEDEEDDEDEDEDEDEIEPAAMKAAAAA 181
Query: 306 DGQVEEEPLNSEDDVSDEEGQE 327
+E+ + EDD D++ +E
Sbjct: 182 PASEDEDDEDDEDDEDDDDDEE 203
Score = 39.7 bits (91), Expect = 0.004
Identities = 25/94 (26%), Positives = 42/94 (44%), Gaps = 29/94 (30%)
Query: 257 QPQAQPAQTQAPLVLQVDGTGDTSSEEDEDEEEDYDDDEEEDKEKDGAEDGQVEEEP--- 313
+P A A AP + EDED+E+D DD++++D E+D +E+ +E P
Sbjct: 171 EPAAMKAAAAAP------------ASEDEDDEDDEDDEDDDDDEEDDSEEEAMETTPAKG 218
Query: 314 --------------LNSEDDVSDEEGQELFDTEN 333
ED+ D+E ++ D E+
Sbjct: 219 KKAAKVVPVKAKNVAEDEDEEEDDEDEDDDDDED 252
Score = 39.7 bits (91), Expect = 0.004
Identities = 25/115 (21%), Positives = 58/115 (50%), Gaps = 6/115 (5%)
Query: 252 ATGQQQPQAQPAQTQAPLVLQVDGTGDTSSEEDEDEEEDYDDDEEEDKEKDGAEDGQVEE 311
A G++ + P + + + + D ++D+DE+++ DDDE++++E++ E+ V+E
Sbjct: 216 AKGKKAAKVVPVKAKNVAEDEDEEEDDEDEDDDDDEDDEDDDDEDDEEEEEEEEEEPVKE 275
Query: 312 EPLNSEDDVSDEEG------QELFDTENVVVCQYDKIHRSKNKWKFHLKDGIMNL 360
P + +++ ++ Q++ TE + + NK LK GI ++
Sbjct: 276 APGKRKKEMAKQKAAPEAKKQKVEGTEPTTAFNLFVGNLNFNKSAPELKTGISDV 330
Score = 34.7 bits (78), Expect = 0.14
Identities = 25/102 (24%), Positives = 39/102 (38%), Gaps = 23/102 (22%)
Query: 249 QITATGQQQPQAQPAQTQAPLVLQVDGTGDTSSEEDEDEEEDY----------------- 291
+I + A PA D D EED+ EEE
Sbjct: 169 EIEPAAMKAAAAAPASEDEDDEDDEDDEDDDDDEEDDSEEEAMETTPAKGKKAAKVVPVK 228
Query: 292 ------DDDEEEDKEKDGAEDGQVEEEPLNSEDDVSDEEGQE 327
D+DEEED E + +D + +E+ + +D+ +EE +E
Sbjct: 229 AKNVAEDEDEEEDDEDEDDDDDEDDEDDDDEDDEEEEEEEEE 270
>gi|61676188 HECT, UBA and WWE domain containing 1 [Homo sapiens]
Length = 4374
Score = 48.9 bits (115), Expect = 7e-06
Identities = 23/73 (31%), Positives = 42/73 (57%), Gaps = 5/73 (6%)
Query: 278 DTSSEEDEDEEEDYDDDEEEDKEKDGAEDGQVEEEPLNSEDDVSDEEGQ-----ELFDTE 332
D S +E+E+EEED +DD+E+D+ ++G ED + + ++D D E FD E
Sbjct: 2429 DDSQDEEEEEEEDEEDDQEDDEGEEGDEDDDDDGSEMELDEDYPDMNASPLVRFERFDRE 2488
Query: 333 NVVVCQYDKIHRS 345
+ ++ ++D + S
Sbjct: 2489 DDLIIEFDNMFSS 2501
Score = 41.2 bits (95), Expect = 0.002
Identities = 24/86 (27%), Positives = 43/86 (50%), Gaps = 9/86 (10%)
Query: 250 ITATGQQQPQAQPAQTQAPLVLQVDGTGDTSSE--------EDEDEEEDYDDDEEEDKEK 301
++ +G+ + Q +AP L T + E EDE+E +D ++++
Sbjct: 2369 VSRSGEDESQEDVLMDEAPSNLSQASTLQANREDSMNILDPEDEEEHTQEEDSSGSNEDE 2428
Query: 302 DGAEDGQVEEEPLNSEDDVSDEEGQE 327
D ++D + EEE + EDD D+EG+E
Sbjct: 2429 DDSQDEEEEEEE-DEEDDQEDDEGEE 2453
>gi|21735415 centromere protein B [Homo sapiens]
Length = 599
Score = 48.1 bits (113), Expect = 1e-05
Identities = 55/242 (22%), Positives = 102/242 (42%), Gaps = 23/242 (9%)
Query: 108 PASQQATAPQVIVPDSK-------LIQHMNASNMSAAATAATLALPAGVTPVQQILTNSG 160
P + QA P +SK L +++ A + AA + + L AG Q + T+
Sbjct: 250 PRAGQAGLPCDYTANSKGGVTTQALAKYLKALDTRMAAESRRVLLLAGRLAAQSLDTSGL 309
Query: 161 QLLQVVRAANGAQYIFQPQQSVVLQQQVIPQMQPGGVQAPVIQQVLAPLPGGISPQTGVI 220
+ +Q+ F P L++ V+ Q++ G + ++ + +A L G P +
Sbjct: 310 RHVQLA--------FFPPGTVHPLERGVVQQVK-GHYRQAMLLKAMAALEGQ-DPSGLQL 359
Query: 221 IQPQQILFTGNKTQVIPTTVAAPTPAQA------QITATGQQQPQAQPAQTQAPLVLQVD 274
+ + F Q + + A +A T T + + + + + + +
Sbjct: 360 GLTEALHFVAAAWQAVEPSDIAACFREAGFGGGPNATITTSLKSEGEEEEEEEEEEEEEE 419
Query: 275 GTGDTSSEEDEDEEEDYDDDEEEDKEKDGAEDGQVEEEPLNSEDDVSDEEGQELFDTENV 334
G G+ EE E+EEE+ + EE +E++ E+G V+ + ED+ S EG E D
Sbjct: 420 GEGEEEEEEGEEEEEEGGEGEELGEEEEVEEEGDVDSDEEEEEDEESSSEGLEAEDWAQG 479
Query: 335 VV 336
VV
Sbjct: 480 VV 481
Score = 43.5 bits (101), Expect = 3e-04
Identities = 22/62 (35%), Positives = 36/62 (58%), Gaps = 2/62 (3%)
Query: 246 AQAQITATGQQQPQAQPAQTQAPLVLQVDG--TGDTSSEEDEDEEEDYDDDEEEDKEKDG 303
AQ + A G + Q P + ++G D+ SEE++DEEED +D++++D E+DG
Sbjct: 477 AQGVVEAGGSFGAYGAQEEAQCPTLHFLEGGEDSDSDSEEEDDEEEDDEDEDDDDDEEDG 536
Query: 304 AE 305
E
Sbjct: 537 DE 538
>gi|156071452 nardilysin isoform b [Homo sapiens]
Length = 1151
Score = 48.1 bits (113), Expect = 1e-05
Identities = 23/57 (40%), Positives = 36/57 (63%), Gaps = 1/57 (1%)
Query: 277 GDTSSEEDEDEEEDYDDDEEEDKEKDGAEDGQVEEEPLNSEDDVSDEEGQELFDTEN 333
G T + D++EEE+ +++EE+D E GAE +EE + ED+ DE +L DTE+
Sbjct: 135 GKTGNTTDDEEEEEVEEEEEDDDEDSGAEIEDDDEEGFDDEDEFDDEHDDDL-DTED 190
Score = 39.3 bits (90), Expect = 0.006
Identities = 23/57 (40%), Positives = 29/57 (50%)
Query: 276 TGDTSSEEDEDEEEDYDDDEEEDKEKDGAEDGQVEEEPLNSEDDVSDEEGQELFDTE 332
T D EE E+EEED D+D + E D E E+E + DD D E EL + E
Sbjct: 141 TDDEEEEEVEEEEEDDDEDSGAEIEDDDEEGFDDEDEFDDEHDDDLDTEDNELEELE 197
Score = 34.7 bits (78), Expect = 0.14
Identities = 16/41 (39%), Positives = 26/41 (63%), Gaps = 3/41 (7%)
Query: 274 DGTGDTSSEEDEDEEEDYDDDEEEDKEKD---GAEDGQVEE 311
D D+ +E ++D+EE +DD++E D E D ED ++EE
Sbjct: 155 DDDEDSGAEIEDDDEEGFDDEDEFDDEHDDDLDTEDNELEE 195
>gi|156071450 nardilysin isoform a [Homo sapiens]
Length = 1219
Score = 48.1 bits (113), Expect = 1e-05
Identities = 23/57 (40%), Positives = 36/57 (63%), Gaps = 1/57 (1%)
Query: 277 GDTSSEEDEDEEEDYDDDEEEDKEKDGAEDGQVEEEPLNSEDDVSDEEGQELFDTEN 333
G T + D++EEE+ +++EE+D E GAE +EE + ED+ DE +L DTE+
Sbjct: 135 GKTGNTTDDEEEEEVEEEEEDDDEDSGAEIEDDDEEGFDDEDEFDDEHDDDL-DTED 190
Score = 39.3 bits (90), Expect = 0.006
Identities = 23/57 (40%), Positives = 29/57 (50%)
Query: 276 TGDTSSEEDEDEEEDYDDDEEEDKEKDGAEDGQVEEEPLNSEDDVSDEEGQELFDTE 332
T D EE E+EEED D+D + E D E E+E + DD D E EL + E
Sbjct: 141 TDDEEEEEVEEEEEDDDEDSGAEIEDDDEEGFDDEDEFDDEHDDDLDTEDNELEELE 197
Score = 36.6 bits (83), Expect = 0.038
Identities = 20/58 (34%), Positives = 32/58 (55%), Gaps = 3/58 (5%)
Query: 274 DGTGDTSSEEDEDEEEDYDDDEEEDKEKD---GAEDGQVEEEPLNSEDDVSDEEGQEL 328
D D+ +E ++D+EE +DD++E D E D ED ++EE +E E Q+L
Sbjct: 155 DDDEDSGAEIEDDDEEGFDDEDEFDDEHDDDLDTEDNELEELEERAEARKKTTEKQQL 212
Score = 30.4 bits (67), Expect = 2.7
Identities = 13/52 (25%), Positives = 28/52 (53%)
Query: 278 DTSSEEDEDEEEDYDDDEEEDKEKDGAEDGQVEEEPLNSEDDVSDEEGQELF 329
+ EE D+E+++DD+ ++D + + E ++EE + ++ Q LF
Sbjct: 165 EDDDEEGFDDEDEFDDEHDDDLDTEDNELEELEERAEARKKTTEKQQLQSLF 216
>gi|62953127 polyhomeotic 1-like [Homo sapiens]
Length = 1004
Score = 48.1 bits (113), Expect = 1e-05
Identities = 68/256 (26%), Positives = 96/256 (37%), Gaps = 25/256 (9%)
Query: 63 EQQLLLQVQQQHQPQQQQHHHHHHH-----QQAQPQQTVPQQAQTQQVLIPASQQATAPQ 117
+QQ+ + QQQ Q +Q Q H H QQ Q QQ QQ Q Q + A Q P
Sbjct: 396 QQQIAIHHQQQFQHRQSQLLHTATHLQLAQQQQQQQQQQQQQQQPQATTLTAPQPPQVPP 455
Query: 118 V-IVPDSKLIQHMNASNMSAAATAATLALPAGVTPVQQILTNSGQLLQVVRAAN-GAQYI 175
VP S+ Q + ++ L+LP P I S + ++ GA +
Sbjct: 456 TQQVPPSQSQQQAQTLVVQPMLQSSPLSLPPDAAPKPPIPIQSKPPVAPIKPPQLGAAKM 515
Query: 176 FQPQQSVV-LQQQVIPQMQPGGVQAPV--IQQVLAP------LPGGI-SPQTGVIIQPQQ 225
QQ + QV+ QPG QA + Q+ A +PG + S Q + P
Sbjct: 516 SAAQQPPPHIPVQVVGTRQPGTAQAQALGLAQLAAAVPTSRGMPGTVQSGQAHLASSPPS 575
Query: 226 ILFTGNKTQVIPT----TVAAPTPAQAQITATGQQQPQAQPAQTQAPLVLQ---VDGTGD 278
G + PT AP A + G AQ A +Q + G
Sbjct: 576 SQAPGALQECPPTLAPGMTLAPVQGTAHVVKGGATTSSPVVAQVPAAFYMQSVHLPGKPQ 635
Query: 279 T-SSEEDEDEEEDYDD 293
T + + D EE+ DD
Sbjct: 636 TLAVKRKADSEEERDD 651
Score = 42.7 bits (99), Expect = 5e-04
Identities = 48/192 (25%), Positives = 78/192 (40%), Gaps = 30/192 (15%)
Query: 102 TQQVLIP----ASQQATAPQVIVP----DSKLIQHMNASNMSAAATAATL------ALPA 147
+Q +L+P A+ Q P P D+ +Q++ N A+A + A+P
Sbjct: 173 SQLILMPNGAVAAVQQEVPSAQSPGVHADADQVQNLAVRNQQASAQGPQMQGSTQKAIPP 232
Query: 148 GVTPVQQILTNSGQLLQVVRAANGAQYIFQPQQSVVLQQ-------QVIPQMQPGG---V 197
G +PV + S Q L V +A++GA QS+ L Q + M PGG
Sbjct: 233 GASPVSSLSQASSQALAVAQASSGA-----TNQSLNLSQAGGGSGNSIPGSMGPGGGGQA 287
Query: 198 QAPVIQQVLAPLPGGISPQTGV-IIQPQQILFTGNKTQVIPTTVAAPTPAQAQITATGQQ 256
+ Q + + GG P+ G ++QP T +Q T + +A+ +GQQ
Sbjct: 288 HGGLGQLPSSGMGGGSCPRKGTGVVQPLPAAQTVTVSQGSQTEAESAAAKKAEADGSGQQ 347
Query: 257 QPQAQPAQTQAP 268
+T P
Sbjct: 348 NVGMNLTRTATP 359
Score = 40.8 bits (94), Expect = 0.002
Identities = 60/238 (25%), Positives = 86/238 (36%), Gaps = 17/238 (7%)
Query: 52 QSRAVDGFHSEEQQLLLQVQQQHQPQQQQHHHHHHHQQAQPQQTVPQQAQTQQVLIPASQ 111
Q A FH Q L Q H Q +QA T Q QT +
Sbjct: 46 QPNAAQYFHQFMLQQQLSNAQLHSLAAVQQATIAASRQASSPNTSTTQQQTTTTQASINL 105
Query: 112 QATAPQVIVPDSKLIQHMNASNMSAAATAA-TLALPAGVTPVQQIL-TNSGQLLQVVRAA 169
T+ ++ S+ + +A+ ++ + T + P + Q L G LLQV R
Sbjct: 106 ATTSAAQLISRSQSVSSPSATTLTQSVLLGNTTSPPLNQSQAQMYLRPQLGNLLQVNRTL 165
Query: 170 N-----GAQYIFQPQQSVVLQQQVIPQMQPGGVQAPVIQ-QVLAPLPGGISPQTGVIIQP 223
+Q I P +V QQ +P Q GV A Q Q LA + Q P
Sbjct: 166 GRNVPLASQLILMPNGAVAAVQQEVPSAQSPGVHADADQVQNLA-----VRNQQASAQGP 220
Query: 224 QQILFTGNKTQVIPTTVAAPTPAQAQITATGQQQPQAQPAQTQAPLVLQVDGTGDTSS 281
Q G+ + IP A+P + +Q ++ QA T L L G G +S
Sbjct: 221 Q---MQGSTQKAIPPG-ASPVSSLSQASSQALAVAQASSGATNQSLNLSQAGGGSGNS 274
>gi|157743257 POU domain, class 6, transcription factor 2 [Homo
sapiens]
Length = 691
Score = 47.4 bits (111), Expect = 2e-05
Identities = 58/224 (25%), Positives = 81/224 (36%), Gaps = 22/224 (9%)
Query: 50 LMQSRAVDGFHSEEQQLLLQVQQQHQPQQQQHHHHHHHQQAQPQQTVPQQAQTQ------ 103
L +A +S+ QQL LQ+QQQ Q QQQQ +Q QP P Q+Q Q
Sbjct: 166 LQNLQATSSLNSQLQQLQLQLQQQQQ-QQQQQPPPSTNQHPQPAPQAPSQSQQQPLQPTP 224
Query: 104 -QVLIPASQQATAPQVIVPDSKLIQHMNASNMSAAATAATLALPAGVTPVQQILTNSGQL 162
Q PASQQ AP + + Q + S + + P + + L
Sbjct: 225 PQQPPPASQQPPAPTSQLQQAPQPQQHQPHSHSQNQNQPSPTQQSSSPPQKPSQSPGHGL 284
Query: 163 LQVVRAANGAQYIFQPQQSVVLQQQVIPQMQPGGVQAPVIQQVLAPLPGGISPQTGVIIQ 222
+ N Q + P S Q + L+ L G TG ++
Sbjct: 285 PSPLTPPNPLQLVNNPLAS---QAAAAAAAMSSIASSQAFGNALSSLQG----VTGQLV- 336
Query: 223 PQQILFTGNKTQVIPTTVAAPTPAQAQITATGQQQPQAQPAQTQ 266
T + Q+I T P P + A+G Q Q QP Q
Sbjct: 337 ------TNAQGQIIGTIPLMPNPGPSSQAASGTQGLQVQPITPQ 374
Score = 33.1 bits (74), Expect = 0.42
Identities = 52/192 (27%), Positives = 69/192 (35%), Gaps = 32/192 (16%)
Query: 89 QAQPQQTVPQQAQTQQVLIPASQQATAPQVIVP------DSKLIQHMNASNMSAAATAAT 142
Q Q QT P Q L+ A Q A+A ++P + ++ N +
Sbjct: 79 QHQASQTHPPFPVGPQPLLTAQQLASAVAGVMPGGPPALNQPILIPFNMAGQLGGQQGLV 138
Query: 143 LALP-AGVTPVQQILTNSGQ------LLQVVRAANGAQYIFQPQQSVVLQQQVIPQMQPG 195
L LP A +T +Q ++ + LQ ++A + Q Q + QQQ Q QP
Sbjct: 139 LTLPTANLTNIQGLVAAAAAGGIMTLPLQNLQATSSLNSQLQQLQLQLQQQQQQQQQQP- 197
Query: 196 GVQAPVIQQVLAPLPGGISPQTGVIIQPQQILFTGNKTQVIPTTVAAPTPAQAQITA-TG 254
P Q P P S QP Q PT P PA Q A T
Sbjct: 198 ---PPSTNQHPQPAPQAPSQSQQ---QPLQ-----------PTPPQQPPPASQQPPAPTS 240
Query: 255 QQQPQAQPAQTQ 266
Q Q QP Q Q
Sbjct: 241 QLQQAPQPQQHQ 252
Score = 30.0 bits (66), Expect = 3.5
Identities = 53/208 (25%), Positives = 67/208 (32%), Gaps = 35/208 (16%)
Query: 73 QHQPQQQQHHHHHHHQQAQPQQTVPQQAQTQQVLIPASQQATAPQVIVP---------DS 123
QHQ Q H QP T Q A ++P A +++P
Sbjct: 79 QHQASQT---HPPFPVGPQPLLTAQQLASAVAGVMPGGPPALNQPILIPFNMAGQLGGQQ 135
Query: 124 KLIQHMNASNMS-------AAATAATLALPAGVTPVQQILTNSGQLLQVVRAANGAQYIF 176
L+ + +N++ AAA + LP L + Q LQ+ Q
Sbjct: 136 GLVLTLPTANLTNIQGLVAAAAAGGIMTLPLQNLQATSSLNSQLQQLQLQLQQQQQQQQQ 195
Query: 177 QPQQSVVLQQQVIPQMQPGGVQAPVIQQVLAPLPGGISPQTGVIIQPQQILFTGNKTQVI 236
QP S Q PQ P Q QQ L P P PQ Q T Q
Sbjct: 196 QPPPSTNQHPQPAPQ-APSQSQ----QQPLQPTP----PQQPPPASQQPPAPTSQLQQ-- 244
Query: 237 PTTVAAPTPAQAQITATGQQQPQAQPAQ 264
AP P Q Q + Q Q Q P Q
Sbjct: 245 -----APQPQQHQPHSHSQNQNQPSPTQ 267
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.311 0.127 0.357
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 15,232,707
Number of Sequences: 37866
Number of extensions: 843873
Number of successful extensions: 25912
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 687
Number of HSP's successfully gapped in prelim test: 488
Number of HSP's that attempted gapping in prelim test: 8700
Number of HSP's gapped (non-prelim): 8431
length of query: 376
length of database: 18,247,518
effective HSP length: 104
effective length of query: 272
effective length of database: 14,309,454
effective search space: 3892171488
effective search space used: 3892171488
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.