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Search of human proteins with 7706457
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|7706457 A-kinase anchor protein 11 [Homo sapiens]
(1901 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|7706457 A-kinase anchor protein 11 [Homo sapiens] 3776 0.0
gi|217416354 sphingosine kinase type 1-interacting protein isofo... 164 8e-40
gi|217416352 sphingosine kinase type 1-interacting protein isofo... 150 1e-35
gi|21493041 A-kinase anchor protein 3 [Homo sapiens] 54 2e-06
gi|21493039 A-kinase anchor protein 4 isoform 2 [Homo sapiens] 52 7e-06
gi|21493037 A-kinase anchor protein 4 isoform 1 [Homo sapiens] 52 7e-06
gi|13994151 PDZ and LIM domain 1 [Homo sapiens] 43 0.003
gi|20270337 Leo1, Paf1/RNA polymerase II complex component, homo... 41 0.010
gi|10864047 epidermal growth factor receptor pathway substrate 1... 38 0.11
gi|244790020 synaptotagmin-like 2 isoform i [Homo sapiens] 37 0.14
gi|244790013 synaptotagmin-like 2 isoform g [Homo sapiens] 37 0.14
gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens] 37 0.14
gi|24429588 zinc finger protein 532 [Homo sapiens] 37 0.14
gi|239740955 PREDICTED: similar to c114 SLIT-like testicular pro... 37 0.18
gi|239740953 PREDICTED: similar to c114 SLIT-like testicular pro... 37 0.18
gi|116325993 c114 SLIT-like testicular protein [Homo sapiens] 37 0.18
gi|110665701 leucine rich repeat containing 37A [Homo sapiens] 37 0.18
gi|75677612 leucine rich repeat containing 37, member A3 [Homo s... 37 0.18
gi|15011902 synaptotagmin-like 2 isoform a [Homo sapiens] 36 0.31
gi|46488937 interferon alpha/beta receptor 2 isoform a precursor... 36 0.31
gi|122937345 myosin VB [Homo sapiens] 36 0.31
gi|22538387 A-kinase anchor protein 9 isoform 2 [Homo sapiens] 36 0.31
gi|22538393 A-kinase anchor protein 9 isoform 3 [Homo sapiens] 36 0.31
gi|154240671 HEAT repeat family member 7B2 [Homo sapiens] 36 0.31
gi|217416332 trinucleotide repeat containing 6C isoform 1 [Homo ... 36 0.41
gi|33413425 trinucleotide repeat containing 6C isoform 2 [Homo s... 36 0.41
gi|7662208 GTPase regulator associated with the focal adhesion k... 36 0.41
gi|148596949 nucleolar and coiled-body phosphoprotein 1 [Homo sa... 35 0.70
gi|109689705 hypothetical protein LOC140876 [Homo sapiens] 35 0.70
gi|22035679 AT rich interactive domain 4B isoform 2 [Homo sapiens] 35 0.70
>gi|7706457 A-kinase anchor protein 11 [Homo sapiens]
Length = 1901
Score = 3776 bits (9792), Expect = 0.0
Identities = 1901/1901 (100%), Positives = 1901/1901 (100%)
Query: 1 MATFRNNHMKTKASVRKSFSEDVFQSVKSLLQSQKELCSVTAEDCLQQDEHANLTEVTFL 60
MATFRNNHMKTKASVRKSFSEDVFQSVKSLLQSQKELCSVTAEDCLQQDEHANLTEVTFL
Sbjct: 1 MATFRNNHMKTKASVRKSFSEDVFQSVKSLLQSQKELCSVTAEDCLQQDEHANLTEVTFL 60
Query: 61 GFNEETDAAHIQDLAAVSLELPDILNSLHFCSLNENEIICMKNINKPLDISSDPLNQSHP 120
GFNEETDAAHIQDLAAVSLELPDILNSLHFCSLNENEIICMKNINKPLDISSDPLNQSHP
Sbjct: 61 GFNEETDAAHIQDLAAVSLELPDILNSLHFCSLNENEIICMKNINKPLDISSDPLNQSHP 120
Query: 121 SGMLCVMRVSPTSPRLRIDFIFSLLSKYATGIRYTLDTFLHQKHQLETTDEDDDDTNQSV 180
SGMLCVMRVSPTSPRLRIDFIFSLLSKYATGIRYTLDTFLHQKHQLETTDEDDDDTNQSV
Sbjct: 121 SGMLCVMRVSPTSPRLRIDFIFSLLSKYATGIRYTLDTFLHQKHQLETTDEDDDDTNQSV 180
Query: 181 SSIEDDFVTAFEHLEEEETSKPYNDGMNITVLRSQCDAASQTVTGHHLETHDLKILISSG 240
SSIEDDFVTAFEHLEEEETSKPYNDGMNITVLRSQCDAASQTVTGHHLETHDLKILISSG
Sbjct: 181 SSIEDDFVTAFEHLEEEETSKPYNDGMNITVLRSQCDAASQTVTGHHLETHDLKILISSG 240
Query: 241 QQKSLAKPSTSSVNVLGHKELPSVKTSVTTSISEPWTQRSFYRSSNASDKDSDLQKTFFS 300
QQKSLAKPSTSSVNVLGHKELPSVKTSVTTSISEPWTQRSFYRSSNASDKDSDLQKTFFS
Sbjct: 241 QQKSLAKPSTSSVNVLGHKELPSVKTSVTTSISEPWTQRSFYRSSNASDKDSDLQKTFFS 300
Query: 301 SSPAYSSESECSSPSPVIFLDEEGYQKSLKAKLELPKIPVMKDDIEDSDSEVSEFFDSFD 360
SSPAYSSESECSSPSPVIFLDEEGYQKSLKAKLELPKIPVMKDDIEDSDSEVSEFFDSFD
Sbjct: 301 SSPAYSSESECSSPSPVIFLDEEGYQKSLKAKLELPKIPVMKDDIEDSDSEVSEFFDSFD 360
Query: 361 QFDELEQTLETCLFNKDPVIGKSSQRKGHKHGKSCMNPQKFKFDRPALPANVRKPTPRKP 420
QFDELEQTLETCLFNKDPVIGKSSQRKGHKHGKSCMNPQKFKFDRPALPANVRKPTPRKP
Sbjct: 361 QFDELEQTLETCLFNKDPVIGKSSQRKGHKHGKSCMNPQKFKFDRPALPANVRKPTPRKP 420
Query: 421 ESPYGNLCDAPDSPRPVKASREDSGLFSPIRSSAFSPLGGCTPAECFCQTDIGGDRIHEN 480
ESPYGNLCDAPDSPRPVKASREDSGLFSPIRSSAFSPLGGCTPAECFCQTDIGGDRIHEN
Sbjct: 421 ESPYGNLCDAPDSPRPVKASREDSGLFSPIRSSAFSPLGGCTPAECFCQTDIGGDRIHEN 480
Query: 481 HDSVYYTYEDYAKSISCEVLGSVLRTHHTNTLSNINSIKHGENKTVTFKHGNLDQKNKSK 540
HDSVYYTYEDYAKSISCEVLGSVLRTHHTNTLSNINSIKHGENKTVTFKHGNLDQKNKSK
Sbjct: 481 HDSVYYTYEDYAKSISCEVLGSVLRTHHTNTLSNINSIKHGENKTVTFKHGNLDQKNKSK 540
Query: 541 NKSLMIKDSIQKFAADLVEKSFGSAFKDLQKGVSSCTNALYHLAIKLTSSVLQMAFDELR 600
NKSLMIKDSIQKFAADLVEKSFGSAFKDLQKGVSSCTNALYHLAIKLTSSVLQMAFDELR
Sbjct: 541 NKSLMIKDSIQKFAADLVEKSFGSAFKDLQKGVSSCTNALYHLAIKLTSSVLQMAFDELR 600
Query: 601 RQRAFSLKERAISGLANFLVSEALSNALKDLQYVKKQIFTNTVARFAADLAEELVFEGIM 660
RQRAFSLKERAISGLANFLVSEALSNALKDLQYVKKQIFTNTVARFAADLAEELVFEGIM
Sbjct: 601 RQRAFSLKERAISGLANFLVSEALSNALKDLQYVKKQIFTNTVARFAADLAEELVFEGIM 660
Query: 661 EVCQFSYPQTPASPQCGSFDFEDKVVKLYAKDLSESVIQEAFIELSQVDVTFTTKAAVSV 720
EVCQFSYPQTPASPQCGSFDFEDKVVKLYAKDLSESVIQEAFIELSQVDVTFTTKAAVSV
Sbjct: 661 EVCQFSYPQTPASPQCGSFDFEDKVVKLYAKDLSESVIQEAFIELSQVDVTFTTKAAVSV 720
Query: 721 STDNIKYVSAESVVPSTQAVTFSPSFHNQAIMVTKPVQEYKKEYTVQQALFCTSGIVTSI 780
STDNIKYVSAESVVPSTQAVTFSPSFHNQAIMVTKPVQEYKKEYTVQQALFCTSGIVTSI
Sbjct: 721 STDNIKYVSAESVVPSTQAVTFSPSFHNQAIMVTKPVQEYKKEYTVQQALFCTSGIVTSI 780
Query: 781 PVPLAGSALLPYHISSTACQAKAHLSSDDSNSNGDSAQVHIATKNREEKAACLRNICLPS 840
PVPLAGSALLPYHISSTACQAKAHLSSDDSNSNGDSAQVHIATKNREEKAACLRNICLPS
Sbjct: 781 PVPLAGSALLPYHISSTACQAKAHLSSDDSNSNGDSAQVHIATKNREEKAACLRNICLPS 840
Query: 841 EHNPGNQNDFKPTNDDIEMQSSSKLPNDPAIISNFSAAVVHTIVNETLESMTSLEVTKMV 900
EHNPGNQNDFKPTNDDIEMQSSSKLPNDPAIISNFSAAVVHTIVNETLESMTSLEVTKMV
Sbjct: 841 EHNPGNQNDFKPTNDDIEMQSSSKLPNDPAIISNFSAAVVHTIVNETLESMTSLEVTKMV 900
Query: 901 DERTDYLTKSLKEKTPPFSHCDQAVLQCSEASSNKDMFADRLSKSIIKHSIDKSKSVIPN 960
DERTDYLTKSLKEKTPPFSHCDQAVLQCSEASSNKDMFADRLSKSIIKHSIDKSKSVIPN
Sbjct: 901 DERTDYLTKSLKEKTPPFSHCDQAVLQCSEASSNKDMFADRLSKSIIKHSIDKSKSVIPN 960
Query: 961 IDKNAVYKESLPVSGEESQLTPEKSPKFPDSQNQLTHCSLSAAKDCVPECKVSMVHGSSL 1020
IDKNAVYKESLPVSGEESQLTPEKSPKFPDSQNQLTHCSLSAAKDCVPECKVSMVHGSSL
Sbjct: 961 IDKNAVYKESLPVSGEESQLTPEKSPKFPDSQNQLTHCSLSAAKDCVPECKVSMVHGSSL 1020
Query: 1021 ETLPSCPAVTGQKSDLKESAKDQPLKKHNLNSTSLEALSFGQENPFPHSHTFSSTALTCV 1080
ETLPSCPAVTGQKSDLKESAKDQPLKKHNLNSTSLEALSFGQENPFPHSHTFSSTALTCV
Sbjct: 1021 ETLPSCPAVTGQKSDLKESAKDQPLKKHNLNSTSLEALSFGQENPFPHSHTFSSTALTCV 1080
Query: 1081 DGLHVEDKQKVRDRNVIPDTPPSTPLVPSRASSEWDIKKLTKKLKGELAKEFAPATPPST 1140
DGLHVEDKQKVRDRNVIPDTPPSTPLVPSRASSEWDIKKLTKKLKGELAKEFAPATPPST
Sbjct: 1081 DGLHVEDKQKVRDRNVIPDTPPSTPLVPSRASSEWDIKKLTKKLKGELAKEFAPATPPST 1140
Query: 1141 PHNSSVGSLSENEQNTIEKEEFMLKLMRSLSEEVESSESGELPEVDVKSEHSGKKVQFAE 1200
PHNSSVGSLSENEQNTIEKEEFMLKLMRSLSEEVESSESGELPEVDVKSEHSGKKVQFAE
Sbjct: 1141 PHNSSVGSLSENEQNTIEKEEFMLKLMRSLSEEVESSESGELPEVDVKSEHSGKKVQFAE 1200
Query: 1201 ALATHILSLATEMAASHLDNKIIQEPKVKNPCLNVQSQRSVSPTFLNPSDENLKTLCNFA 1260
ALATHILSLATEMAASHLDNKIIQEPKVKNPCLNVQSQRSVSPTFLNPSDENLKTLCNFA
Sbjct: 1201 ALATHILSLATEMAASHLDNKIIQEPKVKNPCLNVQSQRSVSPTFLNPSDENLKTLCNFA 1260
Query: 1261 GDLAAEVITEAEKIAKVRNCMLFKQKKNSCYADGDEDYKVEEKLDIEAVVHPREVDPFIL 1320
GDLAAEVITEAEKIAKVRNCMLFKQKKNSCYADGDEDYKVEEKLDIEAVVHPREVDPFIL
Sbjct: 1261 GDLAAEVITEAEKIAKVRNCMLFKQKKNSCYADGDEDYKVEEKLDIEAVVHPREVDPFIL 1320
Query: 1321 SLPPSSCMSGLMYKYPSCESVTDEYAGHLIQILKQEGGNSELIMDQYANRLAYRSVKSGL 1380
SLPPSSCMSGLMYKYPSCESVTDEYAGHLIQILKQEGGNSELIMDQYANRLAYRSVKSGL
Sbjct: 1321 SLPPSSCMSGLMYKYPSCESVTDEYAGHLIQILKQEGGNSELIMDQYANRLAYRSVKSGL 1380
Query: 1381 QEAAKTTKVQCNSRMFPVPSSQVKTNKELLMFSNKEHHQEADKKRQSKRNEGYFCKNQTC 1440
QEAAKTTKVQCNSRMFPVPSSQVKTNKELLMFSNKEHHQEADKKRQSKRNEGYFCKNQTC
Sbjct: 1381 QEAAKTTKVQCNSRMFPVPSSQVKTNKELLMFSNKEHHQEADKKRQSKRNEGYFCKNQTC 1440
Query: 1441 ERTLDPYRNEVSQLYSFSTSLVHSITKDAKEELTASLVGLPKSLTDSCLFEKSGYEEDNE 1500
ERTLDPYRNEVSQLYSFSTSLVHSITKDAKEELTASLVGLPKSLTDSCLFEKSGYEEDNE
Sbjct: 1441 ERTLDPYRNEVSQLYSFSTSLVHSITKDAKEELTASLVGLPKSLTDSCLFEKSGYEEDNE 1500
Query: 1501 CHVTPELPKSLQPSSQNHRFYHSTGSLNGYGCGDNVVQAVEQYAKKVVDDTLELTLGSTV 1560
CHVTPELPKSLQPSSQNHRFYHSTGSLNGYGCGDNVVQAVEQYAKKVVDDTLELTLGSTV
Sbjct: 1501 CHVTPELPKSLQPSSQNHRFYHSTGSLNGYGCGDNVVQAVEQYAKKVVDDTLELTLGSTV 1560
Query: 1561 FRVSETTKSADRVTYAEKLSPLTGQACRYCDLKELHNCTGNSSQHFFRQGSLASSKPASN 1620
FRVSETTKSADRVTYAEKLSPLTGQACRYCDLKELHNCTGNSSQHFFRQGSLASSKPASN
Sbjct: 1561 FRVSETTKSADRVTYAEKLSPLTGQACRYCDLKELHNCTGNSSQHFFRQGSLASSKPASN 1620
Query: 1621 PKFSSRYQKSRIFHLSVPQIHVNLDKKAVLAEKIVAEAIEKAERELSSTSLAADSGIGQE 1680
PKFSSRYQKSRIFHLSVPQIHVNLDKKAVLAEKIVAEAIEKAERELSSTSLAADSGIGQE
Sbjct: 1621 PKFSSRYQKSRIFHLSVPQIHVNLDKKAVLAEKIVAEAIEKAERELSSTSLAADSGIGQE 1680
Query: 1681 GASFAESLATETMTAAVTNVGHAVSSSKEIEDFQSTESVSSQQMNLSIGDDSTGSWSNLS 1740
GASFAESLATETMTAAVTNVGHAVSSSKEIEDFQSTESVSSQQMNLSIGDDSTGSWSNLS
Sbjct: 1681 GASFAESLATETMTAAVTNVGHAVSSSKEIEDFQSTESVSSQQMNLSIGDDSTGSWSNLS 1740
Query: 1741 FEDEHQDESSSFHHLSESNGNSSSWSSLGLEGDLYEDNLSFPTSDSDGPDDKDEEHEDEV 1800
FEDEHQDESSSFHHLSESNGNSSSWSSLGLEGDLYEDNLSFPTSDSDGPDDKDEEHEDEV
Sbjct: 1741 FEDEHQDESSSFHHLSESNGNSSSWSSLGLEGDLYEDNLSFPTSDSDGPDDKDEEHEDEV 1800
Query: 1801 EGLGQDGKTLLITNIDMEPCTVDPQLRIILQWLIASEAEVAELYFHDSANKEFMLLSKQL 1860
EGLGQDGKTLLITNIDMEPCTVDPQLRIILQWLIASEAEVAELYFHDSANKEFMLLSKQL
Sbjct: 1801 EGLGQDGKTLLITNIDMEPCTVDPQLRIILQWLIASEAEVAELYFHDSANKEFMLLSKQL 1860
Query: 1861 QEKGWKVGDLLQAVLQYYEVMEKASSEERCKSLFDWLLENA 1901
QEKGWKVGDLLQAVLQYYEVMEKASSEERCKSLFDWLLENA
Sbjct: 1861 QEKGWKVGDLLQAVLQYYEVMEKASSEERCKSLFDWLLENA 1901
>gi|217416354 sphingosine kinase type 1-interacting protein isoform 1
[Homo sapiens]
Length = 1700
Score = 164 bits (415), Expect = 8e-40
Identities = 314/1394 (22%), Positives = 565/1394 (40%), Gaps = 269/1394 (19%)
Query: 689 YAKDLSESVIQEAFIELSQVDVTFTTKAAVSVSTDNIK----YVSAESVVPSTQ------ 738
YA +L+ESV+Q+AFI LSQ T ++AVSVS + Y + ++VV +
Sbjct: 391 YATNLAESVLQDAFIRLSQSQSTLPQESAVSVSVGSSLLPSCYSTKDTVVSRSWNELPKI 450
Query: 739 AVTFSPSFHNQAI---MVTKPVQEYKKEYT---------------VQQALFCTSGIVTSI 780
V SP + A + + P E E + ++ AL C + ++ +I
Sbjct: 451 VVVQSPDGSDAAPQPGISSWPEMEVSVETSSILSGENSSRQPQSALEVALACAATVIGTI 510
Query: 781 PVPLAGSALLPYHI-------SSTACQAKAHLSSDDSNSNGDSAQVHIATKNREEKAACL 833
P A L + SS A Q +A + + N S + + A
Sbjct: 511 SSPQATERLKMEQVVSNFPPGSSGALQTQAPQGLKEPSINEYSFPSALCGMTQVASAVA- 569
Query: 834 RNICLPSEHNPGNQNDFKPTNDDIEMQSSSKLPNDPAIISNF--SAAVVHTIVNETLESM 891
+C E + + ++S +P + S A+ ++ E +
Sbjct: 570 --VCGLGEREEVTCSVAPSGSLPPAAEASEAMPPLCGLASMELGKEAIAKGLLKEAALVL 627
Query: 892 TSLEVTKMVDERTDYLTKSLKEKTPPFSHCDQAVLQCSEASSNKDMFADRLSKSIIKHSI 951
T + + D + + + E ++ CSE ++ A LS I++HSI
Sbjct: 628 TRPNTYSSIGDFLDSMNRRIMETA------SKSQTLCSENVVRNEL-AHTLSNVILRHSI 680
Query: 952 DKSKSVIPNIDKNAVYKESLPVSGEESQLTPEKSPKFPDSQNQLTHCSLSAAKDCVPECK 1011
D+ V+ +++ + +++ + E +S NQL D +
Sbjct: 681 DE------------VHHKNMIIDPNDNRHSSEILDTLMESTNQLL-------LDVICFTF 721
Query: 1012 VSMVHGSSLETLPSCPAVTGQKSDLKESAKD--QPLKKHNLNSTSLEALSFGQENPFPHS 1069
M H + L CPAV +++ + + QP + +A +P +S
Sbjct: 722 KKMSH---IVRLGECPAVLSKETIRRRETEPSCQP-SDPGASQAWTKATESSSSSPLSNS 777
Query: 1070 HTFSSTALTCVDGLHV-EDKQKVRDRNVIPDTPPS----TPLVPSRASSEWDIKKL-TKK 1123
H S VDG++ +DK VR T S + VP +++ K++ K
Sbjct: 778 HNTSLVINNLVDGMYSKQDKGGVRPGLFKNPTLQSQLSRSHRVPDSSTATTSSKEIYLKG 837
Query: 1124 LKGELAKE--------FAPATPPSTPHNSSVGSLSENEQNTIE---KEEFMLKLMRSLSE 1172
+ GE K A + +P S S S+ + +I +E++ R
Sbjct: 838 IAGEDTKSPHHSENECRASSEGQRSPTVSQSRSGSQEAEESIHPNTQEKYNCATSRINEV 897
Query: 1173 EVESSESGELPEVDVKSEHSGKK------VQFAEALATHILSLATEMAASHLDNKIIQEP 1226
+V S G+ + +S K FAE LA ++S+ATE+AA LDN ++P
Sbjct: 898 QVNLSLLGDDLLLPAQSTLQTKHPDIYCITDFAEELADTVVSMATEIAAICLDNSSGKQP 957
Query: 1227 -------------KVKNPCLNVQSQ----------RSVSPTFLNP----SDE-------- 1251
PC +++ + R P L+ +DE
Sbjct: 958 WFCAWKRGSEFLMTPNVPCRSLKRKKESQGSGTAVRKHKPPRLSEIKRKTDEHPELKEKL 1017
Query: 1252 ---------NLKTLCN----FAGDLAAEV--ITEAEKIAKV-------RNCMLF-----K 1284
NL+ + + FA ++AA++ +TE + + RN +L +
Sbjct: 1018 MNRVVDESMNLEDVPDSVNLFANEVAAKIMNLTEFSMVDGMWQAQGYPRNRLLSGDRWSR 1077
Query: 1285 QKKNSCYADGDEDYKVEEKLDIEAVVHPREVDPFILSLPPSSCMSGLMYKYPSCESVTDE 1344
K +SC + +ED + ++ ++ LS P S S + K SCES+TDE
Sbjct: 1078 LKASSCESIPEEDSEARAYVNSLGLMST-------LSQPVSRASS--VSKQSSCESITDE 1128
Query: 1345 YAGHLIQILKQEGGNSELIMDQYANRLAYRSVKSGLQEAAK-----TTKVQCNSRMFPVP 1399
++ ++ ++ EG EL++D YA + A + S +Q+A + + + C S+
Sbjct: 1129 FSRFMVNQMENEGRGFELLLDYYAGKNASSILNSAMQQACRKSDHLSVRPSCPSKQSSTE 1188
Query: 1400 SSQVKTNKELLMFSNKEHHQEADKKRQSKR-NEGYFC---KNQTCER--TLDPYRNEVSQ 1453
S + + +L ++ + A +R S+ G ++ C R ++ R+ S+
Sbjct: 1189 SITEEFYRYMLRDIERDSRESASSRRSSQDWTAGLLSPSLRSPVCHRQSSMPDSRSPCSR 1248
Query: 1454 L---YSFSTSLVHSITKDAKEEL-------TASLVGLPKSLTDSCLFEKSGYEEDNECHV 1503
L + + ++ ++ +AS GL KS DSCL+ + G + H+
Sbjct: 1249 LTVNVPIKANSLDGFAQNCPQDFLSVQPVSSASSSGLCKS--DSCLYRRGGTD-----HI 1301
Query: 1504 TPELPKSLQPSSQNHRFYHSTGSLNGYGCGDNVVQAVEQYAKKVVDDTLEL-TLGSTVFR 1562
T L SS ++A+ + K +VDD E T +
Sbjct: 1302 TNMLIHETWASS---------------------IEALMRKNKIIVDDAEEADTEPVSGGS 1340
Query: 1563 VSETTKSADRVTYAEKLS--PLTGQACRYCDLKE-LHNCTGNSSQHFFRQGSLASSKPAS 1619
S+ K A+R+ + S L Q C K+ + C + SL + P
Sbjct: 1341 PSQAEKCANRLAASRMCSGPTLLVQESLDCPRKDSVTECKQPPVSSLSKTASLTNHSPLD 1400
Query: 1620 NPKFSSRYQKSRIFHLSVPQIHVNLDKKAVLAEKIVAEAIEKAERE---------LSSTS 1670
+ K +S Q + +N ++++ + ++ IE +RE LS +S
Sbjct: 1401 SKKETSSCQDP---------VPINHKRRSLCSREVPLIQIETDQREACAGEPEPFLSKSS 1451
Query: 1671 LAADSGIGQEGASFAESLATETMTAAVTNVGHAVSSSKEIEDFQSTESVSSQQMNL---- 1726
L ++ EG S +++ + + T V S ++ E+ +S +
Sbjct: 1452 LLEEA----EGHSNDKNIP-DVVRGGDTAVSACQIHSDSLDTRDVPEAEASTEARAPDEA 1506
Query: 1727 ----SIGDDSTGSWSNLSFEDEHQDESSSFHHLSE---SNGNSSSWSSLGL-EGDLYEDN 1778
S ++STGSW+ L+ E+++ D++SSF LSE SNGNSS+ SSLG+ + D+Y+++
Sbjct: 1507 PNPPSSSEESTGSWTQLANEEDNPDDTSSFLQLSERSMSNGNSSATSSLGIMDLDIYQES 1566
Query: 1779 LSFPTSDSDGPDDKD--EEHEDEVE--------GLGQDGKTLLITNIDMEPCTVDPQLRI 1828
+ ++ ++K + + E G ++LL+ N D+EP D +LR
Sbjct: 1567 MPSSPMINELVEEKKILKGQSESTEAPASGPPTGTASPQRSLLVINFDLEPECPDAELRA 1626
Query: 1829 ILQWLIASEAEVAELYFHDSAN---KEFMLLSKQLQEKGWKVGDLLQAVLQYYEVMEKAS 1885
LQW+ ASE + +YF S ++F+ + + + K WKVGD+ AV+QY ++ E+
Sbjct: 1627 TLQWIAASELGIPTIYFKKSQENRIEKFLDVVQLVHRKSWKVGDIFHAVVQYCKMHEE-- 1684
Query: 1886 SEERCKSLFDWLLE 1899
++ SLFDWLLE
Sbjct: 1685 QKDGRLSLFDWLLE 1698
Score = 70.9 bits (172), Expect = 1e-11
Identities = 60/203 (29%), Positives = 100/203 (49%), Gaps = 24/203 (11%)
Query: 20 SEDVFQSVKSLLQSQKELCSVTAEDCLQQDEHANLTEVTFLGFN---EETDAAHIQD-LA 75
S + +S LQ+Q+ C + +D+ N V F+ + +E H+Q L
Sbjct: 50 SNSLLESTDYWLQNQRMPCQIG----FVEDKSENCASVCFVNLDVNKDECSTEHLQQKLV 105
Query: 76 AVSLELPDILNSLHFCSLNENEIICMK-----NINKPLDISSDPLNQSHPSGMLCVMRVS 130
VS +LP +++S++ ENEI+ + N+ ++S P +C+++ +
Sbjct: 106 NVSPDLPKLISSMNVQQPKENEIVVLSGLASGNLQADFEVSQCPWLPD-----ICLVQCA 160
Query: 131 PTSPRLRIDFIFSLLSKYATGIRYTLDTFLHQKHQLETTD-EDDDDTNQSVSSIEDDFVT 189
+ + I ++K+ G+ + LH LET + +DDTN S+SSIE+DF+T
Sbjct: 161 RGNRPNSTNCIIFEINKFLIGLELVQERQLH----LETNILKLEDDTNCSLSSIEEDFLT 216
Query: 190 AFEHLEEE-ETSKPYNDGMNITV 211
A EHLEEE E + ND NI V
Sbjct: 217 ASEHLEEESEVDESRNDYENINV 239
>gi|217416352 sphingosine kinase type 1-interacting protein isoform 2
[Homo sapiens]
Length = 1671
Score = 150 bits (378), Expect = 1e-35
Identities = 306/1380 (22%), Positives = 547/1380 (39%), Gaps = 270/1380 (19%)
Query: 689 YAKDLSESVIQEAFIELSQVDVTFTTKAAVSVSTDNIK----YVSAESVVPSTQ------ 738
YA +L+ESV+Q+AFI LSQ T ++AVSVS + Y + ++VV +
Sbjct: 391 YATNLAESVLQDAFIRLSQSQSTLPQESAVSVSVGSSLLPSCYSTKDTVVSRSWNELPKI 450
Query: 739 AVTFSPSFHNQAI---MVTKPVQEYKKEYT---------------VQQALFCTSGIVTSI 780
V SP + A + + P E E + ++ AL C + ++ +I
Sbjct: 451 VVVQSPDGSDAAPQPGISSWPEMEVSVETSSILSGENSSRQPQSALEVALACAATVIGTI 510
Query: 781 PVPLAGSALLPYHI-------SSTACQAKAHLSSDDSNSNGDSAQVHIATKNREEKAACL 833
P A L + SS A Q +A + + N S + + A
Sbjct: 511 SSPQATERLKMEQVVSNFPPGSSGALQTQAPQGLKEPSINEYSFPSALCGMTQVASAVA- 569
Query: 834 RNICLPSEHNPGNQNDFKPTNDDIEMQSSSKLPNDPAIISNF--SAAVVHTIVNETLESM 891
+C E + + ++S +P + S A+ ++ E +
Sbjct: 570 --VCGLGEREEVTCSVAPSGSLPPAAEASEAMPPLCGLASMELGKEAIAKGLLKEAALVL 627
Query: 892 TSLEVTKMVDERTDYLTKSLKEKTPPFSHCDQAVLQCSEASSNKDMFADRLSKSIIKHSI 951
T + + D + + + E ++ CSE ++ A LS I++HSI
Sbjct: 628 TRPNTYSSIGDFLDSMNRRIMETA------SKSQTLCSENVVRNEL-AHTLSNVILRHSI 680
Query: 952 DKSKSVIPNIDKNAVYKESLPVSGEESQLTPEKSPKFPDSQNQLTHCSLSAAKDCVPECK 1011
D+ V+ +++ + +++ + E +S NQL D +
Sbjct: 681 DE------------VHHKNMIIDPNDNRHSSEILDTLMESTNQLL-------LDVICFTF 721
Query: 1012 VSMVHGSSLETLPSCPAVTGQKSDLKESAKD--QPLKKHNLNSTSLEALSFGQENPFPHS 1069
M H + L CPAV +++ + + QP + +A +P +S
Sbjct: 722 KKMSH---IVRLGECPAVLSKETIRRRETEPSCQP-SDPGASQAWTKATESSSSSPLSNS 777
Query: 1070 HTFSSTALTCVDGLHV-EDKQKVRDRNVIPDTPPS----TPLVPSRASSEWDIKKL-TKK 1123
H S VDG++ +DK VR T S + VP +++ K++ K
Sbjct: 778 HNTSLVINNLVDGMYSKQDKGGVRPGLFKNPTLQSQLSRSHRVPDSSTATTSSKEIYLKG 837
Query: 1124 LKGELAKE--------FAPATPPSTPHNSSVGSLSENEQNTIE---KEEFMLKLMRSLSE 1172
+ GE K A + +P S S S+ + +I +E++ R
Sbjct: 838 IAGEDTKSPHHSENECRASSEGQRSPTVSQSRSGSQEAEESIHPNTQEKYNCATSRINEV 897
Query: 1173 EVESSESGELPEVDVKSEHSGKK------VQFAEALATHILSLATEMAASHLDNKIIQEP 1226
+V S G+ + +S K FAE LA ++S+ATE+AA LDN ++P
Sbjct: 898 QVNLSLLGDDLLLPAQSTLQTKHPDIYCITDFAEELADTVVSMATEIAAICLDNSSGKQP 957
Query: 1227 -------------KVKNPCLNVQSQ----------RSVSPTFLNP----SDE-------- 1251
PC +++ + R P L+ +DE
Sbjct: 958 WFCAWKRGSEFLMTPNVPCRSLKRKKESQGSGTAVRKHKPPRLSEIKRKTDEHPELKEKL 1017
Query: 1252 ---------NLKTLCN----FAGDLAAEV--ITEAEKIAKV-------RNCMLF-----K 1284
NL+ + + FA ++AA++ +TE + + RN +L +
Sbjct: 1018 MNRVVDESMNLEDVPDSVNLFANEVAAKIMNLTEFSMVDGMWQAQGYPRNRLLSGDRWSR 1077
Query: 1285 QKKNSCYADGDEDYKVEEKLDIEAVVHPREVDPFILSLPPSSCMSGLMYKYPSCESVTDE 1344
K +SC + +ED + ++ ++ LS P S S + K SCES+TDE
Sbjct: 1078 LKASSCESIPEEDSEARAYVNSLGLMST-------LSQPVSRASS--VSKQSSCESITDE 1128
Query: 1345 YAGHLIQILKQEGGNSELIMDQYANRLAYRSVKSGLQEAAK-----TTKVQCNSRMFPVP 1399
++ ++ ++ EG EL++D YA + A + S +Q+A + + + C S+
Sbjct: 1129 FSRFMVNQMENEGRGFELLLDYYAGKNASSILNSAMQQACRKSDHLSVRPSCPSKQSSTE 1188
Query: 1400 SSQVKTNKELLMFSNKEHHQEADKKRQSKR-NEGYFC---KNQTCER--TLDPYRNEVSQ 1453
S + + +L ++ + A +R S+ G ++ C R ++ R+ S+
Sbjct: 1189 SITEEFYRYMLRDIERDSRESASSRRSSQDWTAGLLSPSLRSPVCHRQSSMPDSRSPCSR 1248
Query: 1454 L---YSFSTSLVHSITKDAKEEL-------TASLVGLPKSLTDSCLFEKSGYEEDNECHV 1503
L + + ++ ++ +AS GL KS DSCL+ + G + H+
Sbjct: 1249 LTVNVPIKANSLDGFAQNCPQDFLSVQPVSSASSSGLCKS--DSCLYRRGGTD-----HI 1301
Query: 1504 TPELPKSLQPSSQNHRFYHSTGSLNGYGCGDNVVQAVEQYAKKVVDDTLEL-TLGSTVFR 1562
T L SS ++A+ + K +VDD E T +
Sbjct: 1302 TNMLIHETWASS---------------------IEALMRKNKIIVDDAEEADTEPVSGGS 1340
Query: 1563 VSETTKSADRVTYAEKLS--PLTGQACRYCDLKE-LHNCTGNSSQHFFRQGSLASSKPAS 1619
S+ K A+R+ + S L Q C K+ + C + SL + P
Sbjct: 1341 PSQAEKCANRLAASRMCSGPTLLVQESLDCPRKDSVTECKQPPVSSLSKTASLTNHSPLD 1400
Query: 1620 NPKFSSRYQKSRIFHLSVPQIHVNLDKKAVLAEKIVAEAIEKAERE---------LSSTS 1670
+ K +S Q + +N ++++ + ++ IE +RE LS +S
Sbjct: 1401 SKKETSSCQDP---------VPINHKRRSLCSREVPLIQIETDQREACAGEPEPFLSKSS 1451
Query: 1671 LAADSGIGQEGASFAESLATETMTAAVTNVGHAVSSSKEIEDFQSTESVSSQQMNL---- 1726
L ++ EG S +++ + + T V S ++ E+ +S +
Sbjct: 1452 LLEEA----EGHSNDKNIP-DVVRGGDTAVSACQIHSDSLDTRDVPEAEASTEARAPDEA 1506
Query: 1727 ----SIGDDSTGSWSNLSFEDEHQDESSSFHHLSESNGNSSSWSSLGLEGDLYEDNLSFP 1782
S ++STGSW+ L+ E+++ D++SSF LSE S S L E + +
Sbjct: 1507 PNPPSSSEESTGSWTQLANEEDNPDDTSSFLQLSER-----SMSELVEEKKILKGQSEST 1561
Query: 1783 TSDSDGPDDKDEEHEDEVEGLGQDGKTLLITNIDMEPCTVDPQLRIILQWLIASEAEVAE 1842
+ + GP G ++LL+ N D+EP D +LR LQW+ ASE +
Sbjct: 1562 EAPASGPPT----------GTASPQRSLLVINFDLEPECPDAELRATLQWIAASELGIPT 1611
Query: 1843 LYFHDSAN---KEFMLLSKQLQEKGWKVGDLLQAVLQYYEVMEKASSEERCKSLFDWLLE 1899
+YF S ++F+ + + + K WKVGD+ AV+QY ++ E+ ++ SLFDWLLE
Sbjct: 1612 IYFKKSQENRIEKFLDVVQLVHRKSWKVGDIFHAVVQYCKMHEE--QKDGRLSLFDWLLE 1669
Score = 70.9 bits (172), Expect = 1e-11
Identities = 60/203 (29%), Positives = 100/203 (49%), Gaps = 24/203 (11%)
Query: 20 SEDVFQSVKSLLQSQKELCSVTAEDCLQQDEHANLTEVTFLGFN---EETDAAHIQD-LA 75
S + +S LQ+Q+ C + +D+ N V F+ + +E H+Q L
Sbjct: 50 SNSLLESTDYWLQNQRMPCQIG----FVEDKSENCASVCFVNLDVNKDECSTEHLQQKLV 105
Query: 76 AVSLELPDILNSLHFCSLNENEIICMK-----NINKPLDISSDPLNQSHPSGMLCVMRVS 130
VS +LP +++S++ ENEI+ + N+ ++S P +C+++ +
Sbjct: 106 NVSPDLPKLISSMNVQQPKENEIVVLSGLASGNLQADFEVSQCPWLPD-----ICLVQCA 160
Query: 131 PTSPRLRIDFIFSLLSKYATGIRYTLDTFLHQKHQLETTD-EDDDDTNQSVSSIEDDFVT 189
+ + I ++K+ G+ + LH LET + +DDTN S+SSIE+DF+T
Sbjct: 161 RGNRPNSTNCIIFEINKFLIGLELVQERQLH----LETNILKLEDDTNCSLSSIEEDFLT 216
Query: 190 AFEHLEEE-ETSKPYNDGMNITV 211
A EHLEEE E + ND NI V
Sbjct: 217 ASEHLEEESEVDESRNDYENINV 239
>gi|21493041 A-kinase anchor protein 3 [Homo sapiens]
Length = 853
Score = 53.5 bits (127), Expect = 2e-06
Identities = 31/97 (31%), Positives = 54/97 (55%), Gaps = 5/97 (5%)
Query: 1809 TLLITNIDMEPCTVDPQLRIILQWLIASEAEVAELYF---HDSANKEFMLLSKQLQEKGW 1865
T++++N ++ + QL+ +LQW+ ASE V LYF + ++ + LS +KG
Sbjct: 756 TVIVSNHNLTDTVQNKQLQAVLQWVAASELNVPILYFAGDDEGIQEKLLQLSAAAVDKGC 815
Query: 1866 KVGDLLQAVLQYYE--VMEKASSEERCKSLFDWLLEN 1900
VG++LQ+VL+Y + + +A L DWL+ N
Sbjct: 816 SVGEVLQSVLRYEKERQLNEAVGNVTPLQLLDWLMVN 852
>gi|21493039 A-kinase anchor protein 4 isoform 2 [Homo sapiens]
Length = 845
Score = 51.6 bits (122), Expect = 7e-06
Identities = 32/95 (33%), Positives = 51/95 (53%), Gaps = 5/95 (5%)
Query: 1811 LITNIDMEPCTVDPQLRIILQWLIASEAEVAELYF---HDSANKEFMLLSKQLQEKGWKV 1867
+I N ++ QL+ +LQW+ AS+ V LYF D ++ +S + EKG+ V
Sbjct: 750 VIVNNQCSTNSLQKQLQAVLQWIAASQFNVPMLYFMGDKDGQLEKLPQVSAKAAEKGYSV 809
Query: 1868 GDLLQAVLQYYEVM--EKASSEERCKSLFDWLLEN 1900
G LLQ V+++ + ++A + K L DWLL N
Sbjct: 810 GGLLQEVMKFAKERQPDEAVGKVARKQLLDWLLAN 844
Score = 39.3 bits (90), Expect = 0.037
Identities = 25/85 (29%), Positives = 44/85 (51%), Gaps = 9/85 (10%)
Query: 87 SLHFCSLNENEIICMKNINKPLDISSDPLNQSHPSGMLCVMRVSPTSPRLRIDFIFSLLS 146
+L+ SL E EII +K+ K +QS G +C+ + +P+ P ++++ S L
Sbjct: 59 NLNLGSLEEKEIIVIKDTEKK--------DQSKTEGSVCLFKQAPSDPVSVLNWLLSDLQ 110
Query: 147 KYATGIRYTLDTFLHQ-KHQLETTD 170
KYA G ++ L KH++ T+
Sbjct: 111 KYALGFQHALSPSTSTCKHKVGDTE 135
>gi|21493037 A-kinase anchor protein 4 isoform 1 [Homo sapiens]
Length = 854
Score = 51.6 bits (122), Expect = 7e-06
Identities = 32/95 (33%), Positives = 51/95 (53%), Gaps = 5/95 (5%)
Query: 1811 LITNIDMEPCTVDPQLRIILQWLIASEAEVAELYF---HDSANKEFMLLSKQLQEKGWKV 1867
+I N ++ QL+ +LQW+ AS+ V LYF D ++ +S + EKG+ V
Sbjct: 759 VIVNNQCSTNSLQKQLQAVLQWIAASQFNVPMLYFMGDKDGQLEKLPQVSAKAAEKGYSV 818
Query: 1868 GDLLQAVLQYYEVM--EKASSEERCKSLFDWLLEN 1900
G LLQ V+++ + ++A + K L DWLL N
Sbjct: 819 GGLLQEVMKFAKERQPDEAVGKVARKQLLDWLLAN 853
Score = 39.3 bits (90), Expect = 0.037
Identities = 25/85 (29%), Positives = 44/85 (51%), Gaps = 9/85 (10%)
Query: 87 SLHFCSLNENEIICMKNINKPLDISSDPLNQSHPSGMLCVMRVSPTSPRLRIDFIFSLLS 146
+L+ SL E EII +K+ K +QS G +C+ + +P+ P ++++ S L
Sbjct: 68 NLNLGSLEEKEIIVIKDTEKK--------DQSKTEGSVCLFKQAPSDPVSVLNWLLSDLQ 119
Query: 147 KYATGIRYTLDTFLHQ-KHQLETTD 170
KYA G ++ L KH++ T+
Sbjct: 120 KYALGFQHALSPSTSTCKHKVGDTE 144
>gi|13994151 PDZ and LIM domain 1 [Homo sapiens]
Length = 329
Score = 43.1 bits (100), Expect = 0.003
Identities = 40/162 (24%), Positives = 73/162 (45%), Gaps = 3/162 (1%)
Query: 180 VSSIEDDFVTAFEHLEEEETSKPYNDGMNITVLRSQCDAASQTVTGHHLETHDLKILISS 239
+++I+ + + HLE + K D + +TV RS+ S VT + H K+ ++S
Sbjct: 50 ITAIDGENTSNMTHLEAQNRIKGCTDNLTLTVARSEHKVWSPLVT-EEGKRHPYKMNLAS 108
Query: 240 GQQKSLAKPSTSSVNVLGHKELPSVKTSVTTSISEPWTQRSFYRSSNASDKDSDLQ-KTF 298
Q+ L S + + + P+ T+ ++ Y S N S+ ++ L+ KT
Sbjct: 109 EPQEVLHIGSAHNRSAMPFTASPASSTTARVITNQYNNPAGLYSSENISNFNNALESKTA 168
Query: 299 FSSSPAYSSESECSSPSPVIFLDEEG-YQKSLKAKLELPKIP 339
S A S + + P + +D+E K L+ K EL + P
Sbjct: 169 ASGVEANSRPLDHAQPPSSLVIDKESEVYKMLQEKQELNEPP 210
>gi|20270337 Leo1, Paf1/RNA polymerase II complex component, homolog
[Homo sapiens]
Length = 666
Score = 41.2 bits (95), Expect = 0.010
Identities = 34/120 (28%), Positives = 50/120 (41%), Gaps = 16/120 (13%)
Query: 1701 GHAVSSSKEIEDFQSTESVSSQQMNLSIGDDSTGSWSNLS-------------FEDEHQD 1747
G S E +D S S Q N + G +++GS S+ F D+ +D
Sbjct: 9 GSDADSEAERKDSDSGSDSDSDQENAASGSNASGSESDQDERGDSGQPSNKELFGDDSED 68
Query: 1748 ESSSFHHLSESNGNSSSWSSLGLEGDLYEDNLSFPTSDSDGPDDKDEEHEDEVEGLGQDG 1807
E +S H S+++ S S E +EDN SD D + ++DE EG DG
Sbjct: 69 EGASHHSGSDNHSERSDNRSEASERSDHEDN---DPSDVDQHSGSEAPNDDEDEGHRSDG 125
>gi|10864047 epidermal growth factor receptor pathway substrate
15-like 1 [Homo sapiens]
Length = 864
Score = 37.7 bits (86), Expect = 0.11
Identities = 37/131 (28%), Positives = 52/131 (39%), Gaps = 25/131 (19%)
Query: 336 PKIPVMKDDIEDSD--------SEVSEFFDSFD-----QFDELEQTLETCLFNKDPVIGK 382
P +P D E SD S+ S+ F + D F+ E + +K P G
Sbjct: 696 PSLPSKLDPFESSDPFSSSSVSSKGSDPFGTLDPFGSGSFNSAEGFADFSQMSKPPPSGP 755
Query: 383 SSQRKGHKHGKSCMNPQKFKFDRPALPANVRKPTPRKPESPYG--------NLCDAPDSP 434
+ G +P K K D PALP +KP P +P+ P G D P++P
Sbjct: 756 FTSSLGGAGFSD--DPFKSKQDTPALPP--KKPAPPRPKPPSGKSTPVSQLGSADFPEAP 811
Query: 435 RPVKASREDSG 445
P + DSG
Sbjct: 812 DPFQPLGADSG 822
>gi|244790020 synaptotagmin-like 2 isoform i [Homo sapiens]
Length = 935
Score = 37.4 bits (85), Expect = 0.14
Identities = 78/360 (21%), Positives = 140/360 (38%), Gaps = 55/360 (15%)
Query: 908 TKSLKEKTPPFSHCDQAVLQCSEASSNKDMFADRLSKSIIKHSID-KSKSVIPNIDKNAV 966
T SLK + P + +L+ + +SS+ D R + H+ + KSK V P + +
Sbjct: 261 TDSLKARGAP-----RGILKRNSSSSSTDSETLRYN-----HNFEPKSKIVSPGL---TI 307
Query: 967 YKESLPVSGEESQLTPEKSPKFPDSQNQLTHCSLSAAKDCVPECKVSMVHGSSL------ 1020
++ +S +E L SP +S L H SA KD +P+ ++HG +
Sbjct: 308 HER---ISEKEHSLEDNSSP---NSLEPLKHVRFSAVKDELPQ-SPGLIHGREVGEFSVL 360
Query: 1021 --ETLPSCPAVTGQKSDLKESAKDQPLKKHNL--NSTSLEALSFGQENPFPHSHTFSSTA 1076
+ L + G + + K +K +L STS +S + + S +F
Sbjct: 361 ESDRLKNGMEDAGDTEEFQSDPKPSQYRKPSLFHQSTSSPYVSKSETHQPMTSGSFP--- 417
Query: 1077 LTCVDGLHVEDKQKVRDRNVIPDTPPSTPLVPSRASSEWDIKKLTKKLKGELAKEFAPAT 1136
++GLH + P + ++P + ++ +L L A E +
Sbjct: 418 ---INGLHSHSEV----LTARPQSMENSPTINEPKDKSSELTRLESVLPRSPADELSHCV 470
Query: 1137 PPSTPHNSSVGSLSENEQNTIEKEEFMLK-LMRSLSEEVESSESGELPEVDVKSEHSGKK 1195
P P GS + +Q + E+ +LK L RS + ++ S L ++ S + K
Sbjct: 471 EPE-PSQVPGGSSRDRQQGSEEEPSPVLKTLERSAARKMPSK---SLEDISSDSSNQAKV 526
Query: 1196 VQFAEALATHILSLATEMAASHLDNKIIQEPKVKNPCLNVQSQRSVSPTFLNPSDENLKT 1255
E L ++T + DN K+K +V P FL ++ +T
Sbjct: 527 DNQPEELVRSAEDVST--VPTQPDNPFSHPDKLKRMSKSV-------PAFLQDESDDRET 577
>gi|244790013 synaptotagmin-like 2 isoform g [Homo sapiens]
Length = 934
Score = 37.4 bits (85), Expect = 0.14
Identities = 78/360 (21%), Positives = 140/360 (38%), Gaps = 55/360 (15%)
Query: 908 TKSLKEKTPPFSHCDQAVLQCSEASSNKDMFADRLSKSIIKHSID-KSKSVIPNIDKNAV 966
T SLK + P + +L+ + +SS+ D R + H+ + KSK V P + +
Sbjct: 260 TDSLKARGAP-----RGILKRNSSSSSTDSETLRYN-----HNFEPKSKIVSPGL---TI 306
Query: 967 YKESLPVSGEESQLTPEKSPKFPDSQNQLTHCSLSAAKDCVPECKVSMVHGSSL------ 1020
++ +S +E L SP +S L H SA KD +P+ ++HG +
Sbjct: 307 HER---ISEKEHSLEDNSSP---NSLEPLKHVRFSAVKDELPQ-SPGLIHGREVGEFSVL 359
Query: 1021 --ETLPSCPAVTGQKSDLKESAKDQPLKKHNL--NSTSLEALSFGQENPFPHSHTFSSTA 1076
+ L + G + + K +K +L STS +S + + S +F
Sbjct: 360 ESDRLKNGMEDAGDTEEFQSDPKPSQYRKPSLFHQSTSSPYVSKSETHQPMTSGSFP--- 416
Query: 1077 LTCVDGLHVEDKQKVRDRNVIPDTPPSTPLVPSRASSEWDIKKLTKKLKGELAKEFAPAT 1136
++GLH + P + ++P + ++ +L L A E +
Sbjct: 417 ---INGLHSHSEV----LTARPQSMENSPTINEPKDKSSELTRLESVLPRSPADELSHCV 469
Query: 1137 PPSTPHNSSVGSLSENEQNTIEKEEFMLK-LMRSLSEEVESSESGELPEVDVKSEHSGKK 1195
P P GS + +Q + E+ +LK L RS + ++ S L ++ S + K
Sbjct: 470 EPE-PSQVPGGSSRDRQQGSEEEPSPVLKTLERSAARKMPSK---SLEDISSDSSNQAKV 525
Query: 1196 VQFAEALATHILSLATEMAASHLDNKIIQEPKVKNPCLNVQSQRSVSPTFLNPSDENLKT 1255
E L ++T + DN K+K +V P FL ++ +T
Sbjct: 526 DNQPEELVRSAEDVST--VPTQPDNPFSHPDKLKRMSKSV-------PAFLQDESDDRET 576
>gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens]
Length = 1301
Score = 37.4 bits (85), Expect = 0.14
Identities = 31/133 (23%), Positives = 56/133 (42%), Gaps = 1/133 (0%)
Query: 1667 SSTSLAADSGIGQEGASFAESLATETMTAAVTNVGHAVSSSKEIEDFQS-TESVSSQQMN 1725
SS S ++DS + + ++S + + + + + S + D S ++S S +
Sbjct: 590 SSDSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSKSDSSKSESDSSDSDSKSDSSDSNSSD 649
Query: 1726 LSIGDDSTGSWSNLSFEDEHQDESSSFHHLSESNGNSSSWSSLGLEGDLYEDNLSFPTSD 1785
S DS+ S ++ + D SS S + NSS S + E + S +SD
Sbjct: 650 SSDNSDSSDSSNSSNSSDSSDSSDSSDSSSSSDSSNSSDSSDSSDSSNSSESSDSSDSSD 709
Query: 1786 SDGPDDKDEEHED 1798
SD D D + +
Sbjct: 710 SDSSDSSDSSNSN 722
Score = 37.4 bits (85), Expect = 0.14
Identities = 34/136 (25%), Positives = 61/136 (44%), Gaps = 3/136 (2%)
Query: 1667 SSTSLAADSGIGQEGASFAESLATETMTAAVTNVGHAVSSSKEIEDFQSTESVSSQQMNL 1726
S +S +++S + + ++S ++++ ++ +N + SS+ S S SS +
Sbjct: 690 SDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDSSDS 749
Query: 1727 SIGDDSTGSW--SNLSFEDEHQDESSSFHHLSESNGNSSSWSSLGLEGDLYEDNL-SFPT 1783
S DS+ S SN S + D S S + S+ N SS SS + D+ S +
Sbjct: 750 SNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDS 809
Query: 1784 SDSDGPDDKDEEHEDE 1799
SDS D D + +
Sbjct: 810 SDSSDSSDSDSSNSSD 825
Score = 37.0 bits (84), Expect = 0.18
Identities = 29/138 (21%), Positives = 59/138 (42%), Gaps = 1/138 (0%)
Query: 1662 AERELSSTSLAADSGIGQEGASFAESLATETMTAAVTNVGHAVSSSKEIEDFQSTESVSS 1721
++ + S++S ++DS + + ++S + + ++ ++ ++ SS + S++S +S
Sbjct: 724 SDSDSSNSSDSSDSSNSSDSSDSSDS-SNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNS 782
Query: 1722 QQMNLSIGDDSTGSWSNLSFEDEHQDESSSFHHLSESNGNSSSWSSLGLEGDLYEDNLSF 1781
N S + SN S D S S + NSS S+ D + S
Sbjct: 783 SDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSS 842
Query: 1782 PTSDSDGPDDKDEEHEDE 1799
+SDS D D + +
Sbjct: 843 DSSDSSDGSDSDSSNRSD 860
Score = 36.6 bits (83), Expect = 0.24
Identities = 32/134 (23%), Positives = 61/134 (45%), Gaps = 6/134 (4%)
Query: 1667 SSTSLAADSGIGQEGASFAESL-ATETMTAAVTNVGHAVSSSKEIEDFQSTESVSSQQMN 1725
S++S ++DS + +S ++S ++++ ++ ++ S S + D S++S S N
Sbjct: 663 SNSSDSSDSSDSSDSSSSSDSSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSN 722
Query: 1726 LSIGDDSTGSWSNLSFEDEHQDESSSFHHLSESN-----GNSSSWSSLGLEGDLYEDNLS 1780
S D S S S+ S +SS + S+S+ NSS S D + + S
Sbjct: 723 SSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNS 782
Query: 1781 FPTSDSDGPDDKDE 1794
++DS D +
Sbjct: 783 SDSNDSSNSSDSSD 796
Score = 36.6 bits (83), Expect = 0.24
Identities = 35/141 (24%), Positives = 60/141 (42%), Gaps = 3/141 (2%)
Query: 1667 SSTSLAADSGIGQEGASFAESLATETMTAAVTNVGHAVSSSKEIEDFQSTESVSSQQMNL 1726
S++S ++DS + + ++S + + + + + SS+ S S SS +
Sbjct: 1139 SNSSDSSDSSESSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDS 1198
Query: 1727 SIGDDSTGSWSNLSFEDEHQDESSSFHHLSESNGNSSSWSSLGLEGDLYEDNLSFPTSDS 1786
S DS+ S S+ S + D S S S+ N SS SS D + + S +SDS
Sbjct: 1199 SDSSDSSDS-SDSSDSSDSSDSSDSSDSSDSSDSNESSDSSDS--SDSSDSSNSSDSSDS 1255
Query: 1787 DGPDDKDEEHEDEVEGLGQDG 1807
D + DE + + G
Sbjct: 1256 SDSSDSTSDSNDESDSQSKSG 1276
Score = 36.2 bits (82), Expect = 0.31
Identities = 33/132 (25%), Positives = 58/132 (43%), Gaps = 5/132 (3%)
Query: 1667 SSTSLAADSGIGQEGASFAESLATETMTAAVTNVGHAVSSSKEIEDFQSTESVSSQQMNL 1726
S +S ++DS + + ++S + + ++ ++ + SS + S++S S N
Sbjct: 1175 SDSSNSSDSSDSSDSSDSSDS-SDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSNE 1233
Query: 1727 SIGDDSTGSWSNLSFEDEHQDESSSFHHLSESNGNSSSWSSLGLEGDLYEDNLSFPTSDS 1786
S + S+ S + D S S S+SN S S S G G+ +N S SDS
Sbjct: 1234 SSDSSDSSDSSDSSNSSDSSDSSDSSDSTSDSNDESDSQSKSG-NGN---NNGSDSDSDS 1289
Query: 1787 DGPDDKDEEHED 1798
+G D +D
Sbjct: 1290 EGSDSNHSTSDD 1301
Score = 35.8 bits (81), Expect = 0.41
Identities = 32/127 (25%), Positives = 53/127 (41%), Gaps = 8/127 (6%)
Query: 1673 ADSGIGQEGASFAESLATETMTAAVTNVGHAVSSSKEIEDFQSTESVSSQQMNLSIGDDS 1732
+DSG G+ +S ++S + + + + S S D S++S SS + D S
Sbjct: 540 SDSGKGKSDSSDSDSSDSSNSSDSSDSSDSDSSDSNSSSDSDSSDSDSSDSSDSDSSDSS 599
Query: 1733 TGSWSNLSFEDEHQDESSSFHHLSESNGNSSSWSSLGLEGDLYEDNLSFPTSDSDGPDDK 1792
S S+ S + +SS S+S +SS S + D D+ SDS+ D
Sbjct: 600 NSSDSSDSSDSSDSSDSSDS---SDSKSDSSKSESDSSDSDSKSDS-----SDSNSSDSS 651
Query: 1793 DEEHEDE 1799
D +
Sbjct: 652 DNSDSSD 658
Score = 35.8 bits (81), Expect = 0.41
Identities = 33/136 (24%), Positives = 59/136 (43%), Gaps = 3/136 (2%)
Query: 1665 ELSSTSLAADSGIGQEGASFAESLATETMTAAVTNVGHAVSSSKEIEDFQSTESVSSQQM 1724
E S++S ++DS + S S ++++ ++ N + SS ++ S++S +S
Sbjct: 887 ESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSS--NSSDSSESSNSSDNSNSSDSSNSSDS 944
Query: 1725 NLSIGDDSTGSWSNLSFEDEHQDESSSFHHLSESNGNSSSWSSLGLEGDLYEDNLSFPTS 1784
+ S ++ SN S D S S S + NSS S D + + S +S
Sbjct: 945 SDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSS 1004
Query: 1785 D-SDGPDDKDEEHEDE 1799
D SD D D + +
Sbjct: 1005 DSSDSSDSSDSSNSSD 1020
Score = 35.0 bits (79), Expect = 0.70
Identities = 34/135 (25%), Positives = 59/135 (43%), Gaps = 5/135 (3%)
Query: 1667 SSTSLAADSGIGQEGASFAESLATETMTAAVTNVGHAVSSSKEIEDFQSTESVSSQQMNL 1726
S +S ++DS + ++ ++S +++ ++ ++ S S + D S S S+ N
Sbjct: 735 SDSSNSSDSSDSSDSSNSSDS--SDSSDSSNSSDSSDSSDSSDSSD-SSNSSDSNDSSNS 791
Query: 1727 SIGDDSTGSW--SNLSFEDEHQDESSSFHHLSESNGNSSSWSSLGLEGDLYEDNLSFPTS 1784
S DS+ S SN S + D S S S + NSS S D + + S S
Sbjct: 792 SDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGS 851
Query: 1785 DSDGPDDKDEEHEDE 1799
DSD + D + +
Sbjct: 852 DSDSSNRSDSSNSSD 866
Score = 34.7 bits (78), Expect = 0.91
Identities = 30/106 (28%), Positives = 46/106 (43%), Gaps = 8/106 (7%)
Query: 1705 SSSKEIEDFQSTESVSSQQMNLSIGDDSTGSWSNLSFEDEHQDESSSFHHLSESNGNSSS 1764
S + + S S SS + S DS S SN S + + D SS S+S+ +S+S
Sbjct: 542 SGKGKSDSSDSDSSDSSNSSDSSDSSDSDSSDSNSSSDSDSSDSDSSDSSDSDSSDSSNS 601
Query: 1765 WSSLGLEGDLYEDNLSFPTSDS-DGPDDKDEEHEDEVEGLGQDGKT 1809
D + + S +SDS D D K + + E + D K+
Sbjct: 602 -------SDSSDSSDSSDSSDSSDSSDSKSDSSKSESDSSDSDSKS 640
Score = 34.7 bits (78), Expect = 0.91
Identities = 33/144 (22%), Positives = 57/144 (39%), Gaps = 2/144 (1%)
Query: 1656 AEAIEKAERELSSTSLAADSGIGQEGASFAESLATETMTAAVTNVGHAVSSSKEIEDFQS 1715
+++ ++ + S +S ++DS + +ES + + + + + SS S
Sbjct: 895 SDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSS 954
Query: 1716 TESVSSQQMNLSIGDDSTGSWSNLSFEDEHQDESSSFHHLSESN--GNSSSWSSLGLEGD 1773
S SS N S DS S S+ S +SS S+S+ NSS S D
Sbjct: 955 DSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSD 1014
Query: 1774 LYEDNLSFPTSDSDGPDDKDEEHE 1797
+ S +SDS D + +
Sbjct: 1015 SSNSSDSSNSSDSSNSSDSSDSSD 1038
Score = 34.3 bits (77), Expect = 1.2
Identities = 31/131 (23%), Positives = 56/131 (42%), Gaps = 3/131 (2%)
Query: 1667 SSTSLAADSGIGQEGASFAESLATETMTAA-VTNVGHAVSSSKEIEDFQSTESVSSQQMN 1725
S +S ++DS + + ++S +++ ++ +N + SS + S++S +
Sbjct: 795 SDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSD 854
Query: 1726 LSIGDDSTGSWSNLSFEDEHQDESSSFHHLSESNGNS--SSWSSLGLEGDLYEDNLSFPT 1783
S DS+ S + D SS S + NS SS SS + D + + S +
Sbjct: 855 SSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNESSNSSDSSDSSNSSDSDSSDSSNSSDS 914
Query: 1784 SDSDGPDDKDE 1794
SDS D E
Sbjct: 915 SDSSNSSDSSE 925
Score = 33.9 bits (76), Expect = 1.6
Identities = 33/143 (23%), Positives = 57/143 (39%), Gaps = 8/143 (5%)
Query: 1661 KAERELSSTSLAADSGIGQEGASFAESLATETMTAAVTNVGHAVSSSKEIEDFQSTESVS 1720
K+E + S + +DS S S ++++ ++ ++ S S + S+ S S
Sbjct: 628 KSESDSSDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSD----SSSSSDS 683
Query: 1721 SQQMNLSIGDDSTGSWSNLSFEDEHQDESSSFHHLSESNGNSSSWSSLGLEGDLYEDNLS 1780
S + S DS+ S + D +SS S SN + S S+ D + S
Sbjct: 684 SNSSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDS 743
Query: 1781 FPTSDS----DGPDDKDEEHEDE 1799
+SDS D D D + +
Sbjct: 744 SDSSDSSNSSDSSDSSDSSNSSD 766
Score = 33.9 bits (76), Expect = 1.6
Identities = 33/133 (24%), Positives = 59/133 (44%), Gaps = 3/133 (2%)
Query: 1667 SSTSLAADSGIGQEGASFAESLATETMTAAVTNVGHAVSSSKEIEDFQ--STESVSSQQM 1724
S +S ++DS G + S S ++ + ++ ++ S S + D S S SS
Sbjct: 839 SDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNESSNSSDSSDSS 898
Query: 1725 NLSIGDDSTGSWSNLSFEDEHQDESSSFHHLSESNGNSSSWSSLGLEGDLYEDNLSFPTS 1784
N S D S S S+ S + + +SS + S+ N NSS S+ D + + S +S
Sbjct: 899 NSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSD-NSNSSDSSNSSDSSDSSDSSNSSDSS 957
Query: 1785 DSDGPDDKDEEHE 1797
+S + + +
Sbjct: 958 NSSDSSNSSDSSD 970
Score = 33.1 bits (74), Expect = 2.7
Identities = 31/134 (23%), Positives = 57/134 (42%), Gaps = 3/134 (2%)
Query: 1667 SSTSLAADSGIGQEGASFAESLATETMTAAVTNVGHAVSSSKEIEDFQSTESVSSQQMNL 1726
SS S ++DS + + ++S ++++ +++ ++ + SS D + + S +
Sbjct: 549 SSDSDSSDSSNSSDSSDSSDSDSSDSNSSSDSDSSDSDSSDSSDSDSSDSSNSSDSSDSS 608
Query: 1727 SIGDDSTGSWSNLSFEDEHQDESSSFHHLSESNG---NSSSWSSLGLEGDLYEDNLSFPT 1783
D S S S+ S D + ES S S+S+ NSS S D + S +
Sbjct: 609 DSSDSSDSSDSSDSKSDSSKSESDSSDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDS 668
Query: 1784 SDSDGPDDKDEEHE 1797
SDS D +
Sbjct: 669 SDSSDSSDSSSSSD 682
Score = 33.1 bits (74), Expect = 2.7
Identities = 27/151 (17%), Positives = 63/151 (41%)
Query: 1656 AEAIEKAERELSSTSLAADSGIGQEGASFAESLATETMTAAVTNVGHAVSSSKEIEDFQS 1715
+++ + ++ + S +S +++S +S + + + ++ ++ + +SS + S
Sbjct: 702 SDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDS 761
Query: 1716 TESVSSQQMNLSIGDDSTGSWSNLSFEDEHQDESSSFHHLSESNGNSSSWSSLGLEGDLY 1775
+ S S + S + + S+ + D S S + SN + SS SS + D
Sbjct: 762 SNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSS 821
Query: 1776 EDNLSFPTSDSDGPDDKDEEHEDEVEGLGQD 1806
+ S +SDS + + + G D
Sbjct: 822 NSSDSSNSSDSSDSSNSSDSSDSSDSSDGSD 852
Score = 33.1 bits (74), Expect = 2.7
Identities = 28/131 (21%), Positives = 56/131 (42%), Gaps = 1/131 (0%)
Query: 1667 SSTSLAADSGIGQEGASFAESLATETMTAAVTNVGHAVSSSKEIEDFQSTESVSSQQMNL 1726
S +S ++D+ + ++ ++S + + ++ ++ ++ SS + S S SS N
Sbjct: 924 SESSNSSDNSNSSDSSNSSDS-SDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNS 982
Query: 1727 SIGDDSTGSWSNLSFEDEHQDESSSFHHLSESNGNSSSWSSLGLEGDLYEDNLSFPTSDS 1786
S DS+ S + D SS S + NSS S+ + + + S +SDS
Sbjct: 983 SDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDS 1042
Query: 1787 DGPDDKDEEHE 1797
D + +
Sbjct: 1043 SDSSDSSDSSD 1053
Score = 32.7 bits (73), Expect = 3.5
Identities = 29/131 (22%), Positives = 54/131 (41%), Gaps = 1/131 (0%)
Query: 1667 SSTSLAADSGIGQEGASFAESLATETMTAAVTNVGHAVSSSKEIEDFQSTESVSSQQMNL 1726
S +S ++DS + ++ ++S + + ++ ++ + SS S S SS +
Sbjct: 936 SDSSNSSDSSDSSDSSNSSDS-SNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDS 994
Query: 1727 SIGDDSTGSWSNLSFEDEHQDESSSFHHLSESNGNSSSWSSLGLEGDLYEDNLSFPTSDS 1786
S DS+ S + D +SS S + NSS S D + + S +SDS
Sbjct: 995 SDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDS 1054
Query: 1787 DGPDDKDEEHE 1797
D + +
Sbjct: 1055 SNSSDSSDSSD 1065
Score = 32.7 bits (73), Expect = 3.5
Identities = 29/131 (22%), Positives = 49/131 (37%)
Query: 1667 SSTSLAADSGIGQEGASFAESLATETMTAAVTNVGHAVSSSKEIEDFQSTESVSSQQMNL 1726
S +S ++DS + + + S + + + + + SS S S SS N
Sbjct: 998 SDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNS 1057
Query: 1727 SIGDDSTGSWSNLSFEDEHQDESSSFHHLSESNGNSSSWSSLGLEGDLYEDNLSFPTSDS 1786
S DS+ S + D SS S + NSS S D + + S +SDS
Sbjct: 1058 SDSSDSSDSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDS 1117
Query: 1787 DGPDDKDEEHE 1797
+ + +
Sbjct: 1118 SDSSNSSDSSD 1128
Score = 32.3 bits (72), Expect = 4.5
Identities = 30/108 (27%), Positives = 44/108 (40%), Gaps = 15/108 (13%)
Query: 1700 VGHAVSSSKEIEDFQSTESVSSQQMNLSIGDDSTGSWSNLSFEDEHQDESSSFHHLSESN 1759
VGH+ + S D + + M GDD N S E D+++S ES+
Sbjct: 436 VGHSNTGSDSNSDGYDSYDFDDKSMQ---GDDP-----NSSDESNGNDDANS-----ESD 482
Query: 1760 GNSSSWSSLGLEGDLYEDNLSFPTSDSDGPDDKDEEHEDEVEGLGQDG 1807
NSSS D +DN + SDS G +D D + + +G
Sbjct: 483 NNSSSRGDASYNSDESKDNGN--GSDSKGAEDDDSDSTSDTNNSDSNG 528
Score = 32.3 bits (72), Expect = 4.5
Identities = 76/406 (18%), Positives = 144/406 (35%), Gaps = 17/406 (4%)
Query: 795 SSTACQAKAHLSSDDSNSNGDSAQVHIATKNREEKAACLRNICLPSEHNPGNQNDFKPTN 854
S+++ + + SSD S+S+ S + NR + + + N + +D +N
Sbjct: 827 SNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSN 886
Query: 855 DDIEMQSSSKLPN----DPAIISNFSAAVVHTIVNETLESMTSLEVTKMVD--ERTDYLT 908
+ SS N D + SN S + + +++ ES S + + D +D
Sbjct: 887 ESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSD 946
Query: 909 KSLKEKTPPFSHCDQAVLQCSEASSNKDMFADRLSKSIIKHSIDKSKSVIPNIDKNAVYK 968
S + S+ + + SN +D + S S D S S + N+
Sbjct: 947 SSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNS--S 1004
Query: 969 ESLPVSGEESQLTPEKSPKFPDSQNQLTHCSLSAAKDCVPECKVSMVHGSSLETLPSCPA 1028
+S S S DS N S + D S SS + S +
Sbjct: 1005 DSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSS 1064
Query: 1029 VTGQKSDLKES--AKDQPLKKHNLNSTSLEALSFGQENPFPHSHTFSSTALTCVDGLHVE 1086
+ SD +S + D + +S++ S ++ + SS + D +
Sbjct: 1065 DSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSS 1124
Query: 1087 DKQKVRDRNVIPDTPPSTPLVPSRASSEWDIKKLTKKLKGELAKEFAPATPPSTPHNSSV 1146
D D + D+ S+ S SS D + + + + ++ S NSS
Sbjct: 1125 DSSDSSDSSDSSDSSNSSDSSDSSESS--DSSDSSDSSDSSDSSDSSDSSDSSDSSNSSD 1182
Query: 1147 GSLSENEQNTIEKEEFMLKLMRSLSEEVESSESGELPEVDVKSEHS 1192
S S + ++ + + S+ +SS+S + + S+ S
Sbjct: 1183 SSDSSDSSDSSDSSD-----SSDSSDSSDSSDSSDSSDSSDSSDSS 1223
Score = 32.3 bits (72), Expect = 4.5
Identities = 30/131 (22%), Positives = 51/131 (38%), Gaps = 1/131 (0%)
Query: 1667 SSTSLAADSGIGQEGASFAESLATETMTAAVTNVGHAVSSSKEIEDFQSTESVSSQQMNL 1726
S S ++DS + + ++S + + + + + SS D S S SS +
Sbjct: 930 SDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSD-SSDSSNSSDSSDS 988
Query: 1727 SIGDDSTGSWSNLSFEDEHQDESSSFHHLSESNGNSSSWSSLGLEGDLYEDNLSFPTSDS 1786
S DS+ S + + D SS S + NSS S+ D + + S +SDS
Sbjct: 989 SDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDS 1048
Query: 1787 DGPDDKDEEHE 1797
D +
Sbjct: 1049 SDSSDSSNSSD 1059
Score = 32.0 bits (71), Expect = 5.9
Identities = 28/138 (20%), Positives = 57/138 (41%)
Query: 1660 EKAERELSSTSLAADSGIGQEGASFAESLATETMTAAVTNVGHAVSSSKEIEDFQSTESV 1719
+ ++ + S S ++S + + ++S + + + + + SSS S S
Sbjct: 632 DSSDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSSSSSDSSNSSDSSD 691
Query: 1720 SSQQMNLSIGDDSTGSWSNLSFEDEHQDESSSFHHLSESNGNSSSWSSLGLEGDLYEDNL 1779
SS N S DS+ S + S + S+S S ++ +SS S+ D + +
Sbjct: 692 SSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDSSDSSN 751
Query: 1780 SFPTSDSDGPDDKDEEHE 1797
S +SDS + + +
Sbjct: 752 SSDSSDSSDSSNSSDSSD 769
Score = 31.6 bits (70), Expect = 7.7
Identities = 28/131 (21%), Positives = 52/131 (39%)
Query: 1667 SSTSLAADSGIGQEGASFAESLATETMTAAVTNVGHAVSSSKEIEDFQSTESVSSQQMNL 1726
S++S ++DS + + ++S + + + + + SS S S SS+ +
Sbjct: 1028 SNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSESSDS 1087
Query: 1727 SIGDDSTGSWSNLSFEDEHQDESSSFHHLSESNGNSSSWSSLGLEGDLYEDNLSFPTSDS 1786
S +S+ S + D SS S + NSS S D + + S +SDS
Sbjct: 1088 SDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSSDS 1147
Query: 1787 DGPDDKDEEHE 1797
D + +
Sbjct: 1148 SESSDSSDSSD 1158
Score = 31.6 bits (70), Expect = 7.7
Identities = 29/140 (20%), Positives = 53/140 (37%)
Query: 1667 SSTSLAADSGIGQEGASFAESLATETMTAAVTNVGHAVSSSKEIEDFQSTESVSSQQMNL 1726
S +S ++DS + + ++S + + + + + SS S S SS +
Sbjct: 1154 SDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDS 1213
Query: 1727 SIGDDSTGSWSNLSFEDEHQDESSSFHHLSESNGNSSSWSSLGLEGDLYEDNLSFPTSDS 1786
S DS+ S + D ++ SS S + NSS S D D+ S S
Sbjct: 1214 SDSSDSSDSSDSSDSSDSNESSDSSDSSDSSDSSNSSDSSDSSDSSDSTSDSNDESDSQS 1273
Query: 1787 DGPDDKDEEHEDEVEGLGQD 1806
+ + + + + G D
Sbjct: 1274 KSGNGNNNGSDSDSDSEGSD 1293
>gi|24429588 zinc finger protein 532 [Homo sapiens]
Length = 1301
Score = 37.4 bits (85), Expect = 0.14
Identities = 50/214 (23%), Positives = 89/214 (41%), Gaps = 26/214 (12%)
Query: 1051 NSTSLEALSFGQENPFPHSHTFSSTALTCVDGLHVEDKQKVRD---RNVIPDTPPSTPLV 1107
N TSL +++ P SS +C+ + +K + + ++ S+PL
Sbjct: 249 NDTSLPSVA-------PSKTKSSSKLSSCIAAIAALSAKKAASDSCKEPVANSRESSPLP 301
Query: 1108 ------PSRASSEWDIKKLTKKLKGELAKEFAPATPPS-TPHNSSVGSLSENEQNTIEKE 1160
P A + + L K K+ P +P S + NSS GS S +T
Sbjct: 302 KEVNDSPRAADKSPESQNLIDGTKKPSLKQ--PDSPRSISSENSSKGSPSSPAGSTPAIP 359
Query: 1161 EFMLKLMRSLSEEVESSESGELPEVDVKSEHSGKKVQFAEALATHILSLATEMAASHLDN 1220
+ +K +++ S E++ + + LPEVD+ SGKK A +++ T + +S
Sbjct: 360 KVRIKTIKTSSGEIKRTVTRVLPEVDL---DSGKKPSEQTA---SVMASVTSLLSSPASA 413
Query: 1221 KIIQEPKVKNPCLNVQSQRSVSPTFLNPSDENLK 1254
++ P + P + +VSP L P +K
Sbjct: 414 AVLSSPP-RAPLQSAVVTNAVSPAELTPKQVTIK 446
>gi|239740955 PREDICTED: similar to c114 SLIT-like testicular
protein isoform 1 [Homo sapiens]
Length = 1635
Score = 37.0 bits (84), Expect = 0.18
Identities = 31/115 (26%), Positives = 56/115 (48%), Gaps = 9/115 (7%)
Query: 238 SSGQQKSLAKPSTSSVNVLGHKELPSVKTSVTTSISEPWTQRSFYRSSNASDKDSDLQKT 297
SS QQ++ A P SS+ L LP+ + SV P +++Y N + K +D++ T
Sbjct: 255 SSMQQEAPALPPESSMESL---TLPNHEVSV----QPPGEDQAYYHLPNITVKPADVEVT 307
Query: 298 FFSSSPAYSSESECSSPSPVIFLDE-EGYQKSLKAKLELPKIPVMKDDIEDSDSE 351
S + S+ +P+ F +E E +A +E P +P M+ ++ S+ +
Sbjct: 308 ITSEPTNETESSQAQQETPIQFPEEVEPSATQQEAPIE-PPVPPMEHELSISEQQ 361
>gi|239740953 PREDICTED: similar to c114 SLIT-like testicular
protein isoform 2 [Homo sapiens]
Length = 1700
Score = 37.0 bits (84), Expect = 0.18
Identities = 31/115 (26%), Positives = 56/115 (48%), Gaps = 9/115 (7%)
Query: 238 SSGQQKSLAKPSTSSVNVLGHKELPSVKTSVTTSISEPWTQRSFYRSSNASDKDSDLQKT 297
SS QQ++ A P SS+ L LP+ + SV P +++Y N + K +D++ T
Sbjct: 255 SSMQQEAPALPPESSMESL---TLPNHEVSV----QPPGEDQAYYHLPNITVKPADVEVT 307
Query: 298 FFSSSPAYSSESECSSPSPVIFLDE-EGYQKSLKAKLELPKIPVMKDDIEDSDSE 351
S + S+ +P+ F +E E +A +E P +P M+ ++ S+ +
Sbjct: 308 ITSEPTNETESSQAQQETPIQFPEEVEPSATQQEAPIE-PPVPPMEHELSISEQQ 361
>gi|116325993 c114 SLIT-like testicular protein [Homo sapiens]
Length = 1700
Score = 37.0 bits (84), Expect = 0.18
Identities = 31/115 (26%), Positives = 56/115 (48%), Gaps = 9/115 (7%)
Query: 238 SSGQQKSLAKPSTSSVNVLGHKELPSVKTSVTTSISEPWTQRSFYRSSNASDKDSDLQKT 297
SS QQ++ A P SS+ L LP+ + SV P +++Y N + K +D++ T
Sbjct: 255 SSMQQEAPALPPESSMESL---TLPNHEVSV----QPPGEDQAYYHLPNITVKPADVEVT 307
Query: 298 FFSSSPAYSSESECSSPSPVIFLDE-EGYQKSLKAKLELPKIPVMKDDIEDSDSE 351
S + S+ +P+ F +E E +A +E P +P M+ ++ S+ +
Sbjct: 308 ITSEPTNETESSQAQQETPIQFPEEVEPSATQQEAPIE-PPVPPMEHELSISEQQ 361
>gi|110665701 leucine rich repeat containing 37A [Homo sapiens]
Length = 1700
Score = 37.0 bits (84), Expect = 0.18
Identities = 31/115 (26%), Positives = 56/115 (48%), Gaps = 9/115 (7%)
Query: 238 SSGQQKSLAKPSTSSVNVLGHKELPSVKTSVTTSISEPWTQRSFYRSSNASDKDSDLQKT 297
SS QQ++ A P SS+ L LP+ + SV P +++Y N + K +D++ T
Sbjct: 255 SSMQQEAPALPPESSMESL---TLPNHEVSV----QPPGEDQAYYHLPNITVKPADVEVT 307
Query: 298 FFSSSPAYSSESECSSPSPVIFLDE-EGYQKSLKAKLELPKIPVMKDDIEDSDSE 351
S + S+ +P+ F +E E +A +E P +P M+ ++ S+ +
Sbjct: 308 ITSEPTNETESSQAQQETPIQFPEEVEPSATQQEAPIE-PPVPPMEHELSISEQQ 361
>gi|75677612 leucine rich repeat containing 37, member A3 [Homo
sapiens]
Length = 1634
Score = 37.0 bits (84), Expect = 0.18
Identities = 31/115 (26%), Positives = 56/115 (48%), Gaps = 9/115 (7%)
Query: 238 SSGQQKSLAKPSTSSVNVLGHKELPSVKTSVTTSISEPWTQRSFYRSSNASDKDSDLQKT 297
SS QQ++ A P SS+ L LP+ + SV P +++Y N + K +D++ T
Sbjct: 255 SSMQQEAPALPPESSMESL---TLPNHEVSV----QPPGEDQAYYHLPNITVKPADVEVT 307
Query: 298 FFSSSPAYSSESECSSPSPVIFLDE-EGYQKSLKAKLELPKIPVMKDDIEDSDSE 351
S + S+ +P+ F +E E +A +E P +P M+ ++ S+ +
Sbjct: 308 ITSEPTNETESSQAQQETPIQFPEEVEPSATQQEAPIE-PPVPPMEHELSISEQQ 361
>gi|15011902 synaptotagmin-like 2 isoform a [Homo sapiens]
Length = 910
Score = 36.2 bits (82), Expect = 0.31
Identities = 69/302 (22%), Positives = 120/302 (39%), Gaps = 50/302 (16%)
Query: 908 TKSLKEKTPPFSHCDQAVLQCSEASSNKDMFADRLSKSIIKHSID-KSKSVIPNIDKNAV 966
T SLK + P + +L+ + +SS+ D R + H+ + KSK V P + +
Sbjct: 260 TDSLKARGAP-----RGILKRNSSSSSTDSETLRYN-----HNFEPKSKIVSPGL---TI 306
Query: 967 YKESLPVSGEESQLTPEKSPKFPDSQNQLTHCSLSAAKDCVPECKVSMVHGSSL------ 1020
++ +S +E L SP +S L H SA KD +P+ ++HG +
Sbjct: 307 HER---ISEKEHSLEDNSSP---NSLEPLKHVRFSAVKDELPQ-SPGLIHGREVGEFSVL 359
Query: 1021 --ETLPSCPAVTGQKSDLKESAKDQPLKKHNL--NSTSLEALSFGQENPFPHSHTFSSTA 1076
+ L + G + + K +K +L STS +S + + S +F
Sbjct: 360 ESDRLKNGMEDAGDTEEFQSDPKPSQYRKPSLFHQSTSSPYVSKSETHQPMTSGSFP--- 416
Query: 1077 LTCVDGLHVEDKQKVRDRNVIPDTPPSTPLVPSRASSEWDIKKLTKKLKGELAKEFAPAT 1136
++GLH + P + ++P + ++ +L L A E +
Sbjct: 417 ---INGLHSHSEV----LTARPQSMENSPTINEPKDKSSELTRLESVLPRSPADELSHCV 469
Query: 1137 PPSTPHNSSVGSLSENEQNTIEKEEFMLKL--------MRSLSEEVESSESGELPEVDVK 1188
P P GS + +Q + E+ +LK M S S E SS+S +VD +
Sbjct: 470 EPE-PSQVPGGSSRDRQQGSEEEPSPVLKTLERSAARKMPSKSLEDISSDSSNQAKVDNQ 528
Query: 1189 SE 1190
E
Sbjct: 529 PE 530
>gi|46488937 interferon alpha/beta receptor 2 isoform a precursor
[Homo sapiens]
Length = 515
Score = 36.2 bits (82), Expect = 0.31
Identities = 50/204 (24%), Positives = 83/204 (40%), Gaps = 18/204 (8%)
Query: 1065 PFPHSHTFSSTALTCVDGLHVEDKQKVRDRNVIPDTPPSTPLVPSRASSEWDIKKLTKKL 1124
PFP+ A+ V+ +++ K+KV D N ++ T P + + + LT +
Sbjct: 289 PFPNLPPLE--AMDMVEVIYINRKKKVWDYNYDDESDSDTEAAPRTSGGGYTMHGLTVRP 346
Query: 1125 KGELAKEFAPATPPSTPHNSSVGSLSE--NEQNTIEKEE-FMLKLMRSLSEEVESSESGE 1181
G+ A + + P + L E E T+ K+ L+L+ E +S
Sbjct: 347 LGQ-ASATSTESQLIDPESEEEPDLPEVDVELPTMPKDSPQQLELLSGPCERRKSPLQDP 405
Query: 1182 LPEVDVKS-EHSGKKVQFAEALATHILSL----------ATEMAASHLDNKI-IQEPKVK 1229
PE D S E SG ++ F L + L + A M +SHL+ + ++P
Sbjct: 406 FPEEDYSSTEGSGGRITFNVDLNSVFLRVLDDEDSDDLEAPLMLSSHLEEMVDPEDPDNV 465
Query: 1230 NPCLNVQSQRSVSPTFLNPSDENL 1253
+ S PTF +PS E L
Sbjct: 466 QSNHLLASGEGTQPTFPSPSSEGL 489
>gi|122937345 myosin VB [Homo sapiens]
Length = 1848
Score = 36.2 bits (82), Expect = 0.31
Identities = 60/281 (21%), Positives = 106/281 (37%), Gaps = 25/281 (8%)
Query: 1628 QKSRIFHLSVPQIHVNLDKKAVLA-EKIVAEAIE----KAERELSSTSLAADSGIGQEGA 1682
Q S+ PQ ++LD A LA + + +E K + +L+ A Q +
Sbjct: 1173 QDSKKVQAEPPQTDIDLDPNADLAYNSLKRQELESENKKLKNDLNELRKAVADQATQNNS 1232
Query: 1683 SFAESLATETMTAAVTNVGHAVSSSKEIEDFQSTESVSSQQMNLSIGD-----DSTGSWS 1737
S + + + + KE T+ VS+ Q L+ + ++ SW
Sbjct: 1233 SHGSPDSYSLLLNQLKLAHEELEVRKEEVLILRTQIVSADQRRLAGRNAEPNINARSSWP 1292
Query: 1738 NLSFEDEHQDESSSFHHLSESNGNSSSWSSLGLEGDL---YEDNLSFPTSDSDGPDDKDE 1794
N + +D ++H + ++N + W L +G+L Y+ +
Sbjct: 1293 NSEKHVDQEDAIEAYHGVCQTNSKTEDWGYLNEDGELGLAYQGLKQVARLLEAQLQAQSL 1352
Query: 1795 EHEDEVEGLGQDGKTLLITNIDMEPCTVDPQLRIILQWLIASEAEVAELYFHDSANK--E 1852
EHE+EVE L ++ +D Q + Q L+ S E ++
Sbjct: 1353 EHEEEVEHLK--------AQLEALKEEMDKQQQTFCQTLLLSPEAQVEFGVQQEISRLTN 1404
Query: 1853 FMLLSKQLQEKGWKVGDLLQAVLQYYEVMEKASSEERCKSL 1893
L K+L EK K L+ L+ Y M+KA E ++L
Sbjct: 1405 ENLDLKELVEKLEKNERKLKKQLKIY--MKKAQDLEAAQAL 1443
>gi|22538387 A-kinase anchor protein 9 isoform 2 [Homo sapiens]
Length = 3907
Score = 36.2 bits (82), Expect = 0.31
Identities = 39/174 (22%), Positives = 75/174 (43%), Gaps = 9/174 (5%)
Query: 1714 QSTESVSSQQMNLSIGDDSTGSWSNLSFEDEHQDESSSFHHLSESNGNSSSWSSLGLEGD 1773
Q E V+ +++SI S +S E+ S H + + + + E
Sbjct: 1439 QLEEEVAKVIVSMSIAFAQQTELSRISGGKENTASSKQAHAVCQQEQHYFN------EMK 1492
Query: 1774 LYEDNLSFPTSDSDGPDDKDEEHEDEVEGLGQDGKTLLITNIDME--PCTVDPQLRIILQ 1831
L +D + F T ++ K EE + + LG+ GK +L++N D P + D L I +
Sbjct: 1493 LSQDQIGFQTFETVDVKFK-EEFKPLSKELGEHGKEILLSNSDPHDIPESKDCVLTISEE 1551
Query: 1832 WLIASEAEVAELYFHDSANKEFMLLSKQLQEKGWKVGDLLQAVLQYYEVMEKAS 1885
+ + HD + M S+QL ++ D+ Q +++ Y+ ++A+
Sbjct: 1552 MFSKDKTFIVRQSIHDEISVSSMDASRQLMLNEEQLEDMRQELVRQYQEHQQAT 1605
>gi|22538393 A-kinase anchor protein 9 isoform 3 [Homo sapiens]
Length = 3899
Score = 36.2 bits (82), Expect = 0.31
Identities = 39/174 (22%), Positives = 75/174 (43%), Gaps = 9/174 (5%)
Query: 1714 QSTESVSSQQMNLSIGDDSTGSWSNLSFEDEHQDESSSFHHLSESNGNSSSWSSLGLEGD 1773
Q E V+ +++SI S +S E+ S H + + + + E
Sbjct: 1439 QLEEEVAKVIVSMSIAFAQQTELSRISGGKENTASSKQAHAVCQQEQHYFN------EMK 1492
Query: 1774 LYEDNLSFPTSDSDGPDDKDEEHEDEVEGLGQDGKTLLITNIDME--PCTVDPQLRIILQ 1831
L +D + F T ++ K EE + + LG+ GK +L++N D P + D L I +
Sbjct: 1493 LSQDQIGFQTFETVDVKFK-EEFKPLSKELGEHGKEILLSNSDPHDIPESKDCVLTISEE 1551
Query: 1832 WLIASEAEVAELYFHDSANKEFMLLSKQLQEKGWKVGDLLQAVLQYYEVMEKAS 1885
+ + HD + M S+QL ++ D+ Q +++ Y+ ++A+
Sbjct: 1552 MFSKDKTFIVRQSIHDEISVSSMDASRQLMLNEEQLEDMRQELVRQYQEHQQAT 1605
>gi|154240671 HEAT repeat family member 7B2 [Homo sapiens]
Length = 1585
Score = 36.2 bits (82), Expect = 0.31
Identities = 25/91 (27%), Positives = 45/91 (49%), Gaps = 10/91 (10%)
Query: 1786 SDGPDDKDEEH-----EDEVEGLGQDGKTLLITNIDMEPCTVDPQLRIILQWLIASEAEV 1840
S+G DKD+EH E ++ LG+ KT++ N++ E C ++ WL++ +
Sbjct: 847 SEGQTDKDKEHIQFLYERSMDALGKLLKTMMWDNVNAEDC--QEMFNLLQMWLVSQKEWE 904
Query: 1841 AELYFHDSANKEFMLLSKQLQEKGWKVGDLL 1871
E F +A +L + + +K+G LL
Sbjct: 905 RERAFQITAK---VLTNDIEAPENFKIGSLL 932
>gi|217416332 trinucleotide repeat containing 6C isoform 1 [Homo
sapiens]
Length = 1726
Score = 35.8 bits (81), Expect = 0.41
Identities = 30/97 (30%), Positives = 40/97 (41%), Gaps = 7/97 (7%)
Query: 1673 ADSGIGQEGASFAESLATETMTAAVTNVGHAVSSSKEIEDFQST--ESVSSQQMNLSIGD 1730
A SG G G S + +T TAA GHA S + ED T E + + G
Sbjct: 530 APSGPGVWGDSIS---STAVSTAAAAKSGHAWSGAANQEDKSPTWGEPPKPKSQHWGDGQ 586
Query: 1731 DSTGSWSNLSFEDEHQDESSSFHHLSESNGNSSSWSS 1767
S +WS + + D SS HL + N S W +
Sbjct: 587 RSNPAWS--AGGGDWADSSSVLGHLGDGKKNGSGWDA 621
>gi|33413425 trinucleotide repeat containing 6C isoform 2 [Homo
sapiens]
Length = 1690
Score = 35.8 bits (81), Expect = 0.41
Identities = 30/97 (30%), Positives = 40/97 (41%), Gaps = 7/97 (7%)
Query: 1673 ADSGIGQEGASFAESLATETMTAAVTNVGHAVSSSKEIEDFQST--ESVSSQQMNLSIGD 1730
A SG G G S + +T TAA GHA S + ED T E + + G
Sbjct: 530 APSGPGVWGDSIS---STAVSTAAAAKSGHAWSGAANQEDKSPTWGEPPKPKSQHWGDGQ 586
Query: 1731 DSTGSWSNLSFEDEHQDESSSFHHLSESNGNSSSWSS 1767
S +WS + + D SS HL + N S W +
Sbjct: 587 RSNPAWS--AGGGDWADSSSVLGHLGDGKKNGSGWDA 621
>gi|7662208 GTPase regulator associated with the focal adhesion
kinase pp125 isoform a [Homo sapiens]
Length = 814
Score = 35.8 bits (81), Expect = 0.41
Identities = 29/91 (31%), Positives = 45/91 (49%), Gaps = 8/91 (8%)
Query: 365 LEQTLETCLFNKDPVIGKSSQRKGHKHGKSCMNPQKFKFDRP-ALPANVRKPTPRKPESP 423
+ +LE+ N + ++ SS + + + S + K RP +LP N P+P P SP
Sbjct: 620 INSSLESVSSNPNSILNSSSSLQPNMNS-SDPDLAVVKPTRPNSLPPN---PSPTSPLSP 675
Query: 424 YGNLCDAPDSPRPVKASREDSGLFSPIRSSA 454
+ AP SP P ++ DS SP+RS A
Sbjct: 676 SWPMFSAPSSPMPTSSTSSDS---SPVRSVA 703
>gi|148596949 nucleolar and coiled-body phosphoprotein 1 [Homo
sapiens]
Length = 699
Score = 35.0 bits (79), Expect = 0.70
Identities = 85/400 (21%), Positives = 148/400 (37%), Gaps = 42/400 (10%)
Query: 791 PYHISSTACQAKAHLSSDDSNSNGDS------------AQVHIATKNREEKAACLRNICL 838
P ++ A KA S DS+S+ + V TK + A I
Sbjct: 152 PQAKAAKAPPKKAKSSDSDSDSSSEDEPPKNQKPKITPVTVKAQTKAPPKPARAAPKIAN 211
Query: 839 PSEHNPGNQNDFKPTNDDIEMQSSSKLPNDPAIISNFSA-AVVHTIVNETLESMTSLEVT 897
+ + + ++DD E + ++ P A A V T +S +S + +
Sbjct: 212 GKAASSSSSSSSSSSSDDSEEEKAAATPKKTVPKKQVVAKAPVKAATTPTRKSSSSEDSS 271
Query: 898 KMVDERTDYLTKSLKEKTPPFSHCDQAVLQCSEASSNKDMFADRLSKSIIKHS-IDKSKS 956
+E K +K K P+S +V S K + K++ K ++ S+
Sbjct: 272 SDEEEEQK---KPMKNKPGPYS----SVPPPSAPPPKKSLGTQPPKKAVEKQQPVESSED 324
Query: 957 VIPNIDKNAVYKESLPVSGEESQLTPEKSP--KFPDSQNQLTHCSLSAAKDCVPECKVSM 1014
D ++ ++ P S+ T + P K +S + + S S+ D P
Sbjct: 325 SSDESDSSSEEEKKPPTKAVVSKATTKPPPAKKAAESSSDSSD-SDSSEDDEAPSKPAGT 383
Query: 1015 VHGSSLETLPSCPAVTGQKSDLKESAKD-QP-------LKKHNLNSTSLEALSFGQENPF 1066
SS + PAVT + +K +A QP L + +S+S E S +E
Sbjct: 384 TKNSSNK-----PAVTTKSPAVKPAAAPKQPVGGGQKLLTRKADSSSSEEESSSSEEEKT 438
Query: 1067 PHSHTFSSTALTCVDGLHVEDKQKVR-DRNVIPDTPPSTPLVPSRASSEWDIKKLTKKLK 1125
+ T L + KQ + R+ D+ S+ +S+ +KK +K+
Sbjct: 439 KKMVATTKPKATAKAALSLPAKQAPQGSRDSSSDSDSSSSEEEEEKTSKSAVKKKPQKVA 498
Query: 1126 GELAKEFAPATPPSTPHNSSVGSLSENEQNTIEKEEFMLK 1165
G A P+ P S + S S + ++ E+EE LK
Sbjct: 499 GGAA----PSKPASAKKGKAESSNSSSSDDSSEEEEEKLK 534
>gi|109689705 hypothetical protein LOC140876 [Homo sapiens]
Length = 946
Score = 35.0 bits (79), Expect = 0.70
Identities = 55/213 (25%), Positives = 84/213 (39%), Gaps = 32/213 (15%)
Query: 1608 RQGSLASSKPASNPKFSSRYQKSRIFHLSVPQIHVNLDKKAVLAEKIVAEAIEK--AERE 1665
R+GSL + P S P F RY +LSV Q ++A+L A +I ++ +
Sbjct: 337 RKGSLYNWTPPSTPSFRERY------YLSVLQ---QPTQQALLLGGPRATSILSYLSDSD 387
Query: 1666 LSSTSLAADSGIGQEGASFA--ESLATETMTAAVTN--------VGHAVSSSKEIEDFQS 1715
L SL + S E SF+ + TET T+A T+ G S +E +
Sbjct: 388 LRGPSLRSQSQELPEMDSFSSEDPRDTETSTSASTSDVGFLPLTFGPHASIEEEAREDPL 447
Query: 1716 TESVSSQQMNLSIGD-DSTGSWSNLSFEDEHQDESSSFH----------HLSESNGNSSS 1764
+ + +LS G W NL E + S FH H + G+
Sbjct: 448 PPGLLPEMAHLSGGPFAEQPGWRNLGGESPSLPQGSLFHSGTASSSQNGHEEGATGDRED 507
Query: 1765 WSSLGLEGDLYEDNLSFPTSDSDGPDDKDEEHE 1797
+ LEG L E +DS P ++ E++
Sbjct: 508 GPGVALEGPLQEVLELLRPTDSTQPQLRELEYQ 540
>gi|22035679 AT rich interactive domain 4B isoform 2 [Homo sapiens]
Length = 1226
Score = 35.0 bits (79), Expect = 0.70
Identities = 53/246 (21%), Positives = 99/246 (40%), Gaps = 54/246 (21%)
Query: 1080 VDGLHVEDKQ-KVRDR---------NVIPDTPPSTPLVPSRASSEWDIKKLTKKLKGELA 1129
VD +E+K +V DR N + +TPP+TP PS + +G
Sbjct: 906 VDSKPIEEKTVEVNDRKAEFPSSGSNSVLNTPPTTPESPSSVT----------VTEGSRQ 955
Query: 1130 KEFAPATPPSTPHNSSVGSLSENEQNTIEKEEFMLKLMRSLSEEVESSESGELPEVDVKS 1189
+ + P P+ V S+ +TIE + S +GEL D++S
Sbjct: 956 QSSVTVSEPLAPNQEEVRSIKSETDSTIEVD----------------SVAGELQ--DLQS 997
Query: 1190 EHSGKKVQFAEALATHILSLATEMAASHLDNKIIQEPKVKNP----CLNVQSQRSVSPTF 1245
E + F ++++ S + + H + + +VK+ + + +RS T
Sbjct: 998 EGNSSPAGFDASVSS---SSSNQPEPEHPEKACTGQKRVKDAQGGGSSSKKQKRSHKATV 1054
Query: 1246 LNPSDENLKTLCNFAGDLAA-EVITEAEKIAKVRNCMLFKQKKN--------SCYADGDE 1296
+N + T + + +L+A E IT+++ + V M K+ C +GD+
Sbjct: 1055 VNNKKKGKGTNSSDSEELSAGESITKSQPVKSVSTGMKSHSTKSPARTQSPGKCGKNGDK 1114
Query: 1297 DYKVEE 1302
D ++E
Sbjct: 1115 DPDLKE 1120
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.311 0.126 0.355
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 70,711,019
Number of Sequences: 37866
Number of extensions: 3279378
Number of successful extensions: 10850
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 15
Number of HSP's successfully gapped in prelim test: 77
Number of HSP's that attempted gapping in prelim test: 10479
Number of HSP's gapped (non-prelim): 391
length of query: 1901
length of database: 18,247,518
effective HSP length: 117
effective length of query: 1784
effective length of database: 13,817,196
effective search space: 24649877664
effective search space used: 24649877664
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 70 (31.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.