Search of human proteins with 7706322

Search of human proteins with 7706322

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|7706322 homeobox prox 1 [Homo sapiens]
         (244 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|7706322 homeobox prox 1 [Homo sapiens]                             492   e-139
gi|57863257 T-complex protein 1 isoform a [Homo sapiens]               32   0.50 
gi|55749932 desmin [Homo sapiens]                                      32   0.66 
gi|62414289 vimentin [Homo sapiens]                                    30   2.5  
gi|196115290 glial fibrillary acidic protein isoform 2 [Homo sap...    30   2.5  
gi|4503979 glial fibrillary acidic protein isoform 1 [Homo sapiens]    30   2.5  
gi|4759140 sodium/hydrogen exchanger regulatory factor 1 [Homo s...    30   2.5  
gi|122937398 dynein, cytoplasmic 2, heavy chain 1 [Homo sapiens]       29   3.3  
gi|30410798 APG4 autophagy 4 homolog B isoform b [Homo sapiens]        29   4.3  
gi|47132611 APG4 autophagy 4 homolog B isoform a [Homo sapiens]        29   4.3  
gi|50897852 coiled-coil domain containing 88A isoform 2 [Homo sa...    28   7.3  
gi|40548332 coiled-coil domain containing 137 [Homo sapiens]           28   7.3  
gi|40805868 tumor protein D52-like 2 isoform c [Homo sapiens]          28   7.3  
gi|40805862 tumor protein D52-like 2 isoform f [Homo sapiens]          28   7.3  
gi|40805866 tumor protein D52-like 2 isoform b [Homo sapiens]          28   7.3  
gi|40805860 tumor protein D52-like 2 isoform e [Homo sapiens]          28   7.3  
gi|40805870 tumor protein D52-like 2 isoform d [Homo sapiens]          28   7.3  
gi|40805864 tumor protein D52-like 2 isoform a [Homo sapiens]          28   7.3  
gi|105990539 neurofilament, light polypeptide 68kDa [Homo sapiens]     28   9.5  
gi|75677335 digestive-organ expansion factor homolog [Homo sapiens]    28   9.5  

>gi|7706322 homeobox prox 1 [Homo sapiens]
          Length = 244

 Score =  492 bits (1267), Expect = e-139
 Identities = 244/244 (100%), Positives = 244/244 (100%)

Query: 1   MFRRKLTALDYHNPAGFNCKDETEFRNFIVWLEDQKIRHYKIEDRGNLRNIHSSDWPKFF 60
           MFRRKLTALDYHNPAGFNCKDETEFRNFIVWLEDQKIRHYKIEDRGNLRNIHSSDWPKFF
Sbjct: 1   MFRRKLTALDYHNPAGFNCKDETEFRNFIVWLEDQKIRHYKIEDRGNLRNIHSSDWPKFF 60

Query: 61  EKYLRDVNCPFKIQDRQEAIDWLLGLAVRLEYGDNAEKYKDLVPDNSKTADNATKNAEPL 120
           EKYLRDVNCPFKIQDRQEAIDWLLGLAVRLEYGDNAEKYKDLVPDNSKTADNATKNAEPL
Sbjct: 61  EKYLRDVNCPFKIQDRQEAIDWLLGLAVRLEYGDNAEKYKDLVPDNSKTADNATKNAEPL 120

Query: 121 INLDVNNPDFKAGVMALANLLQIQRHDDYLVMLKAIRILVQERLTQDAVAKANQTKEGLP 180
           INLDVNNPDFKAGVMALANLLQIQRHDDYLVMLKAIRILVQERLTQDAVAKANQTKEGLP
Sbjct: 121 INLDVNNPDFKAGVMALANLLQIQRHDDYLVMLKAIRILVQERLTQDAVAKANQTKEGLP 180

Query: 181 VALDKHILGFDTGDAVLNEAAQILRLLHIEELRELQTKINEAIVAVQAIIADPKTDHRLG 240
           VALDKHILGFDTGDAVLNEAAQILRLLHIEELRELQTKINEAIVAVQAIIADPKTDHRLG
Sbjct: 181 VALDKHILGFDTGDAVLNEAAQILRLLHIEELRELQTKINEAIVAVQAIIADPKTDHRLG 240

Query: 241 KVGR 244
           KVGR
Sbjct: 241 KVGR 244


>gi|57863257 T-complex protein 1 isoform a [Homo sapiens]
          Length = 556

 Score = 32.0 bits (71), Expect = 0.50
 Identities = 28/76 (36%), Positives = 40/76 (52%), Gaps = 12/76 (15%)

Query: 168 AVAKANQTKEGL-PVALDKHILGFDTGDAVL-NEAAQILRLLHIE--------ELRELQT 217
           A + AN  K  L PV LDK ++  D GD  + N+ A IL+LL +E        EL +LQ 
Sbjct: 25  AASIANIVKSSLGPVGLDKMLVD-DIGDVTITNDGATILKLLEVEHPAAKVLCELADLQD 83

Query: 218 K-INEAIVAVQAIIAD 232
           K + +   +V  I A+
Sbjct: 84  KEVGDGTTSVVIIAAE 99


>gi|55749932 desmin [Homo sapiens]
          Length = 470

 Score = 31.6 bits (70), Expect = 0.66
 Identities = 15/37 (40%), Positives = 23/37 (62%)

Query: 197 LNEAAQILRLLHIEELRELQTKINEAIVAVQAIIADP 233
           LNE    L+ +H EE+RELQ ++ E  V V+  ++ P
Sbjct: 232 LNEEIAFLKKVHEEEIRELQAQLQEQQVQVEMDMSKP 268


>gi|62414289 vimentin [Homo sapiens]
          Length = 466

 Score = 29.6 bits (65), Expect = 2.5
 Identities = 14/37 (37%), Positives = 21/37 (56%)

Query: 197 LNEAAQILRLLHIEELRELQTKINEAIVAVQAIIADP 233
           L E    L+ LH EE++ELQ +I E  V +   ++ P
Sbjct: 227 LQEEIAFLKKLHEEEIQELQAQIQEQHVQIDVDVSKP 263


>gi|196115290 glial fibrillary acidic protein isoform 2 [Homo
           sapiens]
          Length = 431

 Score = 29.6 bits (65), Expect = 2.5
 Identities = 15/37 (40%), Positives = 22/37 (59%)

Query: 197 LNEAAQILRLLHIEELRELQTKINEAIVAVQAIIADP 233
           L E  + LR +H EE+RELQ ++    V V+  +A P
Sbjct: 193 LEEEIRFLRKIHEEEVRELQEQLARQQVHVELDVAKP 229


>gi|4503979 glial fibrillary acidic protein isoform 1 [Homo sapiens]
          Length = 432

 Score = 29.6 bits (65), Expect = 2.5
 Identities = 15/37 (40%), Positives = 22/37 (59%)

Query: 197 LNEAAQILRLLHIEELRELQTKINEAIVAVQAIIADP 233
           L E  + LR +H EE+RELQ ++    V V+  +A P
Sbjct: 193 LEEEIRFLRKIHEEEVRELQEQLARQQVHVELDVAKP 229


>gi|4759140 sodium/hydrogen exchanger regulatory factor 1 [Homo
           sapiens]
          Length = 358

 Score = 29.6 bits (65), Expect = 2.5
 Identities = 12/34 (35%), Positives = 24/34 (70%)

Query: 210 EELRELQTKINEAIVAVQAIIADPKTDHRLGKVG 243
           E  +++ ++I  A+ AV+ ++ DP+TD +L K+G
Sbjct: 70  ETHQQVVSRIRAALNAVRLLVVDPETDEQLQKLG 103


>gi|122937398 dynein, cytoplasmic 2, heavy chain 1 [Homo sapiens]
          Length = 4314

 Score = 29.3 bits (64), Expect = 3.3
 Identities = 19/60 (31%), Positives = 26/60 (43%), Gaps = 6/60 (10%)

Query: 49   RNIHSSDWPKFFEKYLRDVNCPFKIQDR----QEAIDW--LLGLAVRLEYGDNAEKYKDL 102
            RN     W KF+E  L D+   + I DR     + + W  + GL     YG   + Y DL
Sbjct: 3885 RNYIPQGWTKFYEFSLSDLRAGYNIIDRLFDGAKDVQWEFVHGLLENAIYGGRIDNYFDL 3944


>gi|30410798 APG4 autophagy 4 homolog B isoform b [Homo sapiens]
          Length = 380

 Score = 28.9 bits (63), Expect = 4.3
 Identities = 26/77 (33%), Positives = 35/77 (45%), Gaps = 7/77 (9%)

Query: 148 DYLVMLKAIRILVQERLTQDAVAKANQTKEGLPVALDKHILGFDTGDAVLNEAAQILRLL 207
           D  V+++ IR     RL + +V  A  T    P   D+H  GF  G  V N  +    L+
Sbjct: 171 DNTVVMEEIR-----RLCRTSVPCAGAT--AFPADSDRHCNGFPAGAEVTNRPSPWRPLV 223

Query: 208 HIEELRELQTKINEAIV 224
            +  LR   T INEA V
Sbjct: 224 LLIPLRLGLTDINEAYV 240


>gi|47132611 APG4 autophagy 4 homolog B isoform a [Homo sapiens]
          Length = 393

 Score = 28.9 bits (63), Expect = 4.3
 Identities = 26/77 (33%), Positives = 35/77 (45%), Gaps = 7/77 (9%)

Query: 148 DYLVMLKAIRILVQERLTQDAVAKANQTKEGLPVALDKHILGFDTGDAVLNEAAQILRLL 207
           D  V+++ IR     RL + +V  A  T    P   D+H  GF  G  V N  +    L+
Sbjct: 171 DNTVVMEEIR-----RLCRTSVPCAGAT--AFPADSDRHCNGFPAGAEVTNRPSPWRPLV 223

Query: 208 HIEELRELQTKINEAIV 224
            +  LR   T INEA V
Sbjct: 224 LLIPLRLGLTDINEAYV 240


>gi|50897852 coiled-coil domain containing 88A isoform 2 [Homo
           sapiens]
          Length = 1843

 Score = 28.1 bits (61), Expect = 7.3
 Identities = 20/85 (23%), Positives = 39/85 (45%)

Query: 92  YGDNAEKYKDLVPDNSKTADNATKNAEPLINLDVNNPDFKAGVMALANLLQIQRHDDYLV 151
           Y ++  + K+L  +N +    AT + + L+ L  +    K     + N L+   H+   +
Sbjct: 876 YKESCVRLKELEKENKELVKRATIDIKTLVTLREDLVSEKLKTQQMNNDLEKLTHELEKI 935

Query: 152 MLKAIRILVQERLTQDAVAKANQTK 176
            L   R+L  E+ T D+  K  ++K
Sbjct: 936 GLNKERLLHDEQSTDDSRYKLLESK 960


>gi|40548332 coiled-coil domain containing 137 [Homo sapiens]
          Length = 289

 Score = 28.1 bits (61), Expect = 7.3
 Identities = 33/128 (25%), Positives = 51/128 (39%), Gaps = 12/128 (9%)

Query: 56  WPKFFEKYLRDVNCPFKIQDRQEAIDWLLGLAVRLEYG-----DNAEKYKDLVPDNSKTA 110
           WP    K  + VNC  K QD QE I + L   +R          N ++ K       KT 
Sbjct: 40  WPGLRSKEKKKVNCKPKNQDEQE-IPFRLREIMRSRQEMKNPISNKKRKKAAQVTFRKTL 98

Query: 111 DNATKNAEPLINLDVNNPDFK--AGVMALANLLQIQRHDDYLVMLKAIRILVQERLTQDA 168
           +   K  EP    D+  P FK   G    A + ++Q+   +++ L   + + Q  +    
Sbjct: 99  EKEAKGEEP----DIAVPKFKQRKGESDGAYIHRMQQEAQHVLFLSKNQAIRQPEVQAAP 154

Query: 169 VAKANQTK 176
             K+ Q K
Sbjct: 155 KEKSEQKK 162


>gi|40805868 tumor protein D52-like 2 isoform c [Homo sapiens]
          Length = 220

 Score = 28.1 bits (61), Expect = 7.3
 Identities = 16/41 (39%), Positives = 22/41 (53%)

Query: 191 DTGDAVLNEAAQILRLLHIEELRELQTKINEAIVAVQAIIA 231
           DTG A    A + L     EELR   TK+ E IV ++ ++A
Sbjct: 28  DTGVAARTPAVEGLTEAEEEELRAELTKVEEEIVTLRQVLA 68


>gi|40805862 tumor protein D52-like 2 isoform f [Homo sapiens]
          Length = 186

 Score = 28.1 bits (61), Expect = 7.3
 Identities = 16/41 (39%), Positives = 22/41 (53%)

Query: 191 DTGDAVLNEAAQILRLLHIEELRELQTKINEAIVAVQAIIA 231
           DTG A    A + L     EELR   TK+ E IV ++ ++A
Sbjct: 28  DTGVAARTPAVEGLTEAEEEELRAELTKVEEEIVTLRQVLA 68


>gi|40805866 tumor protein D52-like 2 isoform b [Homo sapiens]
          Length = 209

 Score = 28.1 bits (61), Expect = 7.3
 Identities = 16/41 (39%), Positives = 22/41 (53%)

Query: 191 DTGDAVLNEAAQILRLLHIEELRELQTKINEAIVAVQAIIA 231
           DTG A    A + L     EELR   TK+ E IV ++ ++A
Sbjct: 28  DTGVAARTPAVEGLTEAEEEELRAELTKVEEEIVTLRQVLA 68


>gi|40805860 tumor protein D52-like 2 isoform e [Homo sapiens]
          Length = 206

 Score = 28.1 bits (61), Expect = 7.3
 Identities = 16/41 (39%), Positives = 22/41 (53%)

Query: 191 DTGDAVLNEAAQILRLLHIEELRELQTKINEAIVAVQAIIA 231
           DTG A    A + L     EELR   TK+ E IV ++ ++A
Sbjct: 28  DTGVAARTPAVEGLTEAEEEELRAELTKVEEEIVTLRQVLA 68


>gi|40805870 tumor protein D52-like 2 isoform d [Homo sapiens]
          Length = 200

 Score = 28.1 bits (61), Expect = 7.3
 Identities = 16/41 (39%), Positives = 22/41 (53%)

Query: 191 DTGDAVLNEAAQILRLLHIEELRELQTKINEAIVAVQAIIA 231
           DTG A    A + L     EELR   TK+ E IV ++ ++A
Sbjct: 28  DTGVAARTPAVEGLTEAEEEELRAELTKVEEEIVTLRQVLA 68


>gi|40805864 tumor protein D52-like 2 isoform a [Homo sapiens]
          Length = 229

 Score = 28.1 bits (61), Expect = 7.3
 Identities = 16/41 (39%), Positives = 22/41 (53%)

Query: 191 DTGDAVLNEAAQILRLLHIEELRELQTKINEAIVAVQAIIA 231
           DTG A    A + L     EELR   TK+ E IV ++ ++A
Sbjct: 28  DTGVAARTPAVEGLTEAEEEELRAELTKVEEEIVTLRQVLA 68


>gi|105990539 neurofilament, light polypeptide 68kDa [Homo sapiens]
          Length = 543

 Score = 27.7 bits (60), Expect = 9.5
 Identities = 32/135 (23%), Positives = 58/135 (42%), Gaps = 21/135 (15%)

Query: 99  YKDLVPDNSKTADNATKNAEPLINLDVNNPDFKAGVMALANLLQIQRHDDYLVMLKAIRI 158
           Y+  + D    A++AT   + L          + G+      LQ +  ++ L    A   
Sbjct: 139 YEQEIRDLRLAAEDATNEKQAL-------QGEREGLEETLRNLQARYEEEVLSREDAEGR 191

Query: 159 LVQERLTQDAVAKANQTKEGLPVALDKHILGFDTGDAVLNEAAQILRLLHIEELRELQTK 218
           L++ R   D  A A          L+K I      D++++E +  L+ +H EE+ ELQ +
Sbjct: 192 LMEARKGADEAALAR-------AELEKRI------DSLMDEIS-FLKKVHEEEIAELQAQ 237

Query: 219 INEAIVAVQAIIADP 233
           I  A ++V+  +  P
Sbjct: 238 IQYAQISVEMDVTKP 252


>gi|75677335 digestive-organ expansion factor homolog [Homo sapiens]
          Length = 756

 Score = 27.7 bits (60), Expect = 9.5
 Identities = 19/58 (32%), Positives = 32/58 (55%), Gaps = 8/58 (13%)

Query: 182 ALDKHILGFDTGDAVLNEAAQILRLLHIEELRELQTKINEAIVAVQAIIADPKTDHRL 239
           +L+ + L  ++GD    +A+Q   L H+   +EL+ K      A+QA+  +PKT H L
Sbjct: 167 SLETNFLEEESGDNSSLKASQDPFLQHVN--KELKEK------AIQAVATNPKTTHEL 216


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.320    0.137    0.402 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 8,344,326
Number of Sequences: 37866
Number of extensions: 330735
Number of successful extensions: 747
Number of sequences better than 10.0: 20
Number of HSP's better than 10.0 without gapping: 13
Number of HSP's successfully gapped in prelim test: 7
Number of HSP's that attempted gapping in prelim test: 730
Number of HSP's gapped (non-prelim): 24
length of query: 244
length of database: 18,247,518
effective HSP length: 99
effective length of query: 145
effective length of database: 14,498,784
effective search space: 2102323680
effective search space used: 2102323680
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 60 (27.7 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.