Guide to the Human Genome
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Search of human proteins with 7706067

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|7706067 ameloblastin precursor [Homo sapiens]
         (447 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|7706067 ameloblastin precursor [Homo sapiens]                      925   0.0  
gi|21312134 mediator complex subunit 15 isoform b [Homo sapiens]       55   1e-07
gi|4502071 amelogenin (X chromosome) isoform 1 precursor [Homo s...    52   1e-06
gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens]     51   2e-06
gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo ...    50   3e-06
gi|149999378 inverted formin 2 isoform 2 [Homo sapiens]                49   7e-06
gi|149999380 inverted formin 2 isoform 1 [Homo sapiens]                49   7e-06
gi|41349482 proline-rich protein BstNI subfamily 1 isoform 1 pre...    49   7e-06
gi|89142735 alpha 3 type IV collagen isoform 4 precursor [Homo s...    48   2e-05
gi|89142733 alpha 3 type IV collagen isoform 2 precursor [Homo s...    48   2e-05
gi|89142730 alpha 3 type IV collagen isoform 1 precursor [Homo s...    48   2e-05
gi|210032580 SET domain containing 1B [Homo sapiens]                   47   4e-05
gi|89142737 alpha 3 type IV collagen isoform 5 precursor [Homo s...    47   5e-05
gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi...    46   6e-05
gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi...    46   6e-05
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi...    44   3e-04
gi|33356556 amelogenin (X chromosome) isoform 3 precursor [Homo ...    44   3e-04
gi|163965366 nascent polypeptide-associated complex alpha subuni...    44   3e-04
gi|239754955 PREDICTED: similar to COL22A1 protein [Homo sapiens]      43   5e-04
gi|15890086 type IV collagen alpha 5 isoform 2 precursor [Homo s...    43   5e-04
gi|4502955 type IV collagen alpha 5 isoform 1 precursor [Homo sa...    43   5e-04
gi|15890088 type IV collagen alpha 5 isoform 3 precursor [Homo s...    43   5e-04
gi|51477700 mediator complex subunit 15 isoform a [Homo sapiens]       43   5e-04
gi|32698936 B-cell CLL/lymphoma 9-like [Homo sapiens]                  43   5e-04
gi|56243590 WD repeat domain 33 isoform 1 [Homo sapiens]               43   5e-04
gi|38787970 tensin like C1 domain containing phosphatase isoform...    42   9e-04
gi|38787957 tensin like C1 domain containing phosphatase isoform...    42   9e-04
gi|38787941 tensin like C1 domain containing phosphatase isoform...    42   9e-04
gi|47132519 Ras association and pleckstrin homology domains 1 is...    42   0.001
gi|24308073 protein tyrosine phosphatase, non-receptor type 23 [...    42   0.001

>gi|7706067 ameloblastin precursor [Homo sapiens]
          Length = 447

 Score =  925 bits (2391), Expect = 0.0
 Identities = 447/447 (100%), Positives = 447/447 (100%)

Query: 1   MSASKIPLFKMKDLILILCLLEMSFAVPFFPQQSGTPGMASLSLETMRQLGSLQRLNTLS 60
           MSASKIPLFKMKDLILILCLLEMSFAVPFFPQQSGTPGMASLSLETMRQLGSLQRLNTLS
Sbjct: 1   MSASKIPLFKMKDLILILCLLEMSFAVPFFPQQSGTPGMASLSLETMRQLGSLQRLNTLS 60

Query: 61  QYSRYGFGKSFNSLWMHGLLPPHSSLPWMRPREHETQQYEYSLPVHPPPLPSQPSLKPQQ 120
           QYSRYGFGKSFNSLWMHGLLPPHSSLPWMRPREHETQQYEYSLPVHPPPLPSQPSLKPQQ
Sbjct: 61  QYSRYGFGKSFNSLWMHGLLPPHSSLPWMRPREHETQQYEYSLPVHPPPLPSQPSLKPQQ 120

Query: 121 PGLKPFLQSAAATTNQATALKEALQPPIHLGHLPLQEGELPLVQQQVAPSDKPPKPELPG 180
           PGLKPFLQSAAATTNQATALKEALQPPIHLGHLPLQEGELPLVQQQVAPSDKPPKPELPG
Sbjct: 121 PGLKPFLQSAAATTNQATALKEALQPPIHLGHLPLQEGELPLVQQQVAPSDKPPKPELPG 180

Query: 181 VDFADPQGPSLPGMDFPDPQGPSLPGLDFADPQGSTIFQIARLISHGPMPQNKQSPLYPG 240
           VDFADPQGPSLPGMDFPDPQGPSLPGLDFADPQGSTIFQIARLISHGPMPQNKQSPLYPG
Sbjct: 181 VDFADPQGPSLPGMDFPDPQGPSLPGLDFADPQGSTIFQIARLISHGPMPQNKQSPLYPG 240

Query: 241 MLYVPFGANQLNAPARLGIMSSEEVAGGREDPMAYGAMFPGFGGMRPGFEGMPHNPAMGG 300
           MLYVPFGANQLNAPARLGIMSSEEVAGGREDPMAYGAMFPGFGGMRPGFEGMPHNPAMGG
Sbjct: 241 MLYVPFGANQLNAPARLGIMSSEEVAGGREDPMAYGAMFPGFGGMRPGFEGMPHNPAMGG 300

Query: 301 DFTLEFDSPVAATKGPENEEGGAQGSPMPEANPDNLENPAFLTELEPAPHAGLLALPKDD 360
           DFTLEFDSPVAATKGPENEEGGAQGSPMPEANPDNLENPAFLTELEPAPHAGLLALPKDD
Sbjct: 301 DFTLEFDSPVAATKGPENEEGGAQGSPMPEANPDNLENPAFLTELEPAPHAGLLALPKDD 360

Query: 361 IPGLPRSPSGKMKGLPSVTPAAADPLMTPELADVYRTYDADMTTSVDFQEEATMDTTMAP 420
           IPGLPRSPSGKMKGLPSVTPAAADPLMTPELADVYRTYDADMTTSVDFQEEATMDTTMAP
Sbjct: 361 IPGLPRSPSGKMKGLPSVTPAAADPLMTPELADVYRTYDADMTTSVDFQEEATMDTTMAP 420

Query: 421 NSLQTSMPGNKAQEPEMMHDAWHFQEP 447
           NSLQTSMPGNKAQEPEMMHDAWHFQEP
Sbjct: 421 NSLQTSMPGNKAQEPEMMHDAWHFQEP 447


>gi|21312134 mediator complex subunit 15 isoform b [Homo sapiens]
          Length = 748

 Score = 55.1 bits (131), Expect = 1e-07
 Identities = 61/217 (28%), Positives = 80/217 (36%), Gaps = 41/217 (18%)

Query: 81  PPHSSLPWMRPREHETQQYEYSLPVHPPPLPSQPSLKPQQPGLKPFLQSAAATTNQATAL 140
           PP  +LP    + H TQ ++      PPP P QP +   QP   P         +QA AL
Sbjct: 281 PPSQALPQQLQQMHHTQHHQ------PPPQPQQPPVAQNQPSQLPPQSQTQPLVSQAQAL 334

Query: 141 KEAL---QPPIHLGHLPL---QEGELPLVQQQ------------VAPSDKPPKPELPGVD 182
              +   QPP+     P+   Q    P VQQQ            VAP  +  +  LP + 
Sbjct: 335 PGQMLYTQPPLKFVRAPMVVQQPPVQPQVQQQQTAVQTAQAAQMVAPGVQVSQSSLPMLS 394

Query: 183 FADP-QGPSLPGMDFPDPQGPSLPGLDFADPQGSTIFQIARLISH---GPMPQNKQSPL- 237
              P Q    P    P PQ    PG   + P  +     A   S     P PQ  QSP+ 
Sbjct: 395 SPSPGQQVQTPQSMPPPPQPSPQPGQPSSQPNSNVSSGPAPSPSSFLPSPSPQPSQSPVT 454

Query: 238 ----------YPGMLYVPFGANQLNAPARLGIMSSEE 264
                      PG L  P   + + +PA  G   +EE
Sbjct: 455 ARTPQNFSVPSPGPLNTPVNPSSVMSPA--GSSQAEE 489


>gi|4502071 amelogenin (X chromosome) isoform 1 precursor [Homo
           sapiens]
          Length = 191

 Score = 51.6 bits (122), Expect = 1e-06
 Identities = 52/182 (28%), Positives = 71/182 (39%), Gaps = 14/182 (7%)

Query: 15  ILILCLLEMSFAVPFFPQQSGTPGMASLSLETMRQLGSLQRLNTLSQYSRYGFGKSFNSL 74
           IL  CLL  +FA+P  P   G PG  + S E +  L   Q +     Y  YG+       
Sbjct: 5   ILFACLLGAAFAMPL-PPHPGHPGYINFSYEVLTPLKWYQSIRP--PYPSYGYEPMGG-- 59

Query: 75  WMHGLLPPHSSLPWMRPREHETQQYEYSLPVHPPPLPSQPSLKPQQPGLK-PFLQSAAAT 133
           W+H  + P   L    P  H  Q +      H P +P+Q  + PQQP +  P   S    
Sbjct: 60  WLHHQIIP--VLSQQHPPTHTLQPHH-----HIPVVPAQQPVIPQQPMMPVPGQHSMTPI 112

Query: 134 TNQATALKEALQPPIHLGHLPLQEGELPLVQQQVAPSDK-PPKPELPGVDFADPQGPSLP 192
            +    L    Q P     +  Q  +    Q  V P    PP+P LP +    P  P LP
Sbjct: 113 QHHQPNLPPPAQQPYQPQPVQPQPHQPMQPQPPVHPMQPLPPQPPLPPMFPMQPLPPMLP 172

Query: 193 GM 194
            +
Sbjct: 173 DL 174


>gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens]
          Length = 416

 Score = 51.2 bits (121), Expect = 2e-06
 Identities = 77/279 (27%), Positives = 89/279 (31%), Gaps = 56/279 (20%)

Query: 104 PVHPPPLPSQPSLKPQQPGLKPFLQSAAATTNQATALKEALQPPIHLGHLPLQEGELPLV 163
           P  PPP P +P   P Q G KP          Q        Q P   G    Q    P  
Sbjct: 191 PQGPPPPPGKPQGPPPQGGNKP----------QGPPPPGKPQGPPPQGDNKSQSARSPPG 240

Query: 164 QQQVAPSDKPPKPELPGVDFADPQGPSLPGMDFPDPQGPSLPGLDFADPQGSTIFQIARL 223
           + Q  P     +P+ P      PQGP   G +   PQGP  PG     PQG      ++ 
Sbjct: 241 KPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGN--KPQGPPPPG----KPQGPPPQGGSKS 294

Query: 224 ISHGPMPQNKQSPLYPGMLYVPFGANQLNAPARLGIMSSEEVAGGREDPMAYGAMFPGFG 283
            S    P   Q P        P G NQ   P            G  + P   G   P  G
Sbjct: 295 RSSRSPPGKPQGP-------PPQGGNQPQGPP--------PPPGKPQGPPPQGGNKPQ-G 338

Query: 284 GMRPGFEGMPHNPAMGGDFTLEFDSPVAATKGPENEEGGAQGSPMPEA--NPDNLENPAF 341
              PG    P  P  GG  +    SP    +GP  +EG     P P A  NP   + P  
Sbjct: 339 PPPPGKPQGP--PPQGGSKSRSARSPPGKPQGPPQQEGNNPQGPPPPAGGNPQQPQAP-- 394

Query: 342 LTELEPAPHAGLLALPKDDIPGLPRSPSGKMKGLPSVTP 380
                          P     G PR P G   G PS  P
Sbjct: 395 ---------------PAGQPQGPPRPPQG---GRPSRPP 415



 Score = 46.2 bits (108), Expect = 6e-05
 Identities = 73/284 (25%), Positives = 85/284 (29%), Gaps = 39/284 (13%)

Query: 104 PVHPPPLPSQPSLKPQQPGLKPFLQSAAATTN----QATALKEALQPPIHLGHLPLQEGE 159
           P  PPP P +P   P Q G KP              Q    +    PP      P Q G 
Sbjct: 68  PQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGN 127

Query: 160 LPLVQQQVAPSDKPPKPELPGVDFADPQGPSLPGMDFPDPQGPSLPGLDFADPQGSTIFQ 219
            P  Q    P  KP  P   G +   PQGP  PG     PQGP         PQG    +
Sbjct: 128 QP--QGPPPPPGKPQGPPPQGGN--KPQGPPPPG----KPQGP--------PPQGDNKSR 171

Query: 220 IARL---ISHGPMPQNKQSPLYPGMLYVPFGANQLNAPARLGIMSSEEVAGGREDPMAYG 276
            +R       GP PQ    P  P     P G  Q   P            G  + P   G
Sbjct: 172 SSRSPPGKPQGPPPQGGNQPQGPP---PPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQG 228

Query: 277 AMFPGFGGMRPGFEGMPHNPAMGGDFTLEFDSPVAATKGPENEEGGAQGSPMPEANPDNL 336
                     PG    P  P  GG+       P    +GP  + G     P P   P   
Sbjct: 229 DNKSQSARSPPGKPQGP--PPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQG- 285

Query: 337 ENPAFLTELEPAPHAGLLALPKDDIPGLPRSPSGKMKGLPSVTP 380
                     P P  G  +      PG P+ P  +    P   P
Sbjct: 286 ----------PPPQGGSKSRSSRSPPGKPQGPPPQGGNQPQGPP 319



 Score = 33.1 bits (74), Expect = 0.53
 Identities = 60/234 (25%), Positives = 71/234 (30%), Gaps = 47/234 (20%)

Query: 166 QVAPSDKPPKPELPGVDFADPQGPSLPGMDFPD-------------------PQGPSLPG 206
           Q AP     KP+ P      PQGP   G + P                    PQGP  PG
Sbjct: 37  QGAPPQGGNKPQGPPSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPG 96

Query: 207 LDFADPQGSTIFQIARLISHGPMPQNKQSPLYPGMLYVPFGANQLNAPARLGIMSSEEVA 266
                PQG            G   ++ +SP        P G NQ   P            
Sbjct: 97  ----KPQGPP--------PQGDKSRSPRSPPGKPQGPPPQGGNQPQGP--------PPPP 136

Query: 267 GGREDPMAYGAMFPGFGGMRPGFEGMPHNPAMGGD-FTLEFDSPVAATKGPENEEGG-AQ 324
           G  + P   G   P      P   G P  P   GD  +    SP    +GP  + G   Q
Sbjct: 137 GKPQGPPPQGGNKP----QGPPPPGKPQGPPPQGDNKSRSSRSPPGKPQGPPPQGGNQPQ 192

Query: 325 GSPMPEANPDNLENPAFLTELEPAPHAGLLALPK--DDIPGLPRSPSGKMKGLP 376
           G P P   P             P P       P   D+     RSP GK +G P
Sbjct: 193 GPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSQSARSPPGKPQGPP 246


>gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo
           sapiens]
          Length = 5537

 Score = 50.4 bits (119), Expect = 3e-06
 Identities = 88/382 (23%), Positives = 138/382 (36%), Gaps = 48/382 (12%)

Query: 79  LLPPHSSLPWMRPRE--HETQQYEYSLPVHPPPLPSQPSLKPQQPGLKPFLQSAAATTNQ 136
           L PP   LP     E  H ++  E S P+ PPP  S  S  P+     P  +S  +   +
Sbjct: 467 LSPPPEELPASPLPEALHLSRPLEES-PLSPPPEESPLSPPPESSPFSPLEESPLSPPEE 525

Query: 137 AT---ALKEALQPPIHLGHL--PLQEGELPLVQQQVAPSDKPPKPELPGVDFADPQGPSL 191
           +    AL+  L PP     L  P +E  L    +++  S  P    L       P  P  
Sbjct: 526 SPPSPALETPLSPPPEASPLSPPFEESPLSPPPEELPTSPPPEASRLSPPPEESPMSP-- 583

Query: 192 PGMDFPDPQGPSLPGLDFADPQGSTIFQIARLISHGPMPQNKQSPLYPGMLYVPFGANQL 251
                P  + P  P      P+ S +F         P P+  +SPL P     P  A++L
Sbjct: 584 -----PPEESPMSP-----PPEASRLFPPFEESPLSPPPE--ESPLSP-----PPEASRL 626

Query: 252 NAPARLGIMSSEEVAGGREDPMAYGAM--FPGFGGMRPGFEGMPHNPAMGGDFTLEFDSP 309
           + P     MS          P     +   P    + P  E  P +P      T     P
Sbjct: 627 SPPPEDSPMSPPPEESPMSPPPEVSRLSPLPVVSRLSPPPEESPLSPPPEESPTSP--PP 684

Query: 310 VAATKGPENEEGGAQGSPMPEANPDNLENPAFLTELEPAPHAGLLALPKDDIPGLPRSPS 369
            A+   P  E+     SP PE +P +           P P   L++LP ++ P LP    
Sbjct: 685 EASRLSPPPEDSPT--SPPPEDSPAS-----------PPPEDSLMSLPLEESPLLPLPEE 731

Query: 370 GKM---KGLPSVTPAAADPLMTPELADVYRTYDADMTTSVDFQEEATMDTTMAPNSLQTS 426
            ++      P ++P   +P ++P   + + +  A+        EE  +        L   
Sbjct: 732 PQLCPRSEGPHLSPRPEEPHLSPRPEEPHLSPQAEEPHLSPQPEEPCLCAVPEEPHLSPQ 791

Query: 427 MPG-NKAQEPEMMHDAWHFQEP 447
             G + + +PE +H +   +EP
Sbjct: 792 AEGPHLSPQPEELHLSPQTEEP 813



 Score = 47.4 bits (111), Expect = 3e-05
 Identities = 78/328 (23%), Positives = 120/328 (36%), Gaps = 43/328 (13%)

Query: 81  PPHSSLPWMRPREHETQQYEYSLPVHPPPLPSQPSLKPQQPGLKPFLQSAAAT-----TN 135
           P +  +P + P E          P+ PPP  S  S  P+   L P  +   A+      +
Sbjct: 433 PLNEEMPLLPPPEES--------PLSPPPEESPTSPPPEASRLSPPPEELPASPLPEALH 484

Query: 136 QATALKEA-LQPPIH---LGHLPLQEGELPLVQQQVA-PSDKPPKPELPGVDFADPQGPS 190
            +  L+E+ L PP     L   P      PL +  ++ P + PP P L       P+   
Sbjct: 485 LSRPLEESPLSPPPEESPLSPPPESSPFSPLEESPLSPPEESPPSPALETPLSPPPEASP 544

Query: 191 LPGMDFPDPQGPSLPGLDFADPQGSTIFQIARLISHGPM-PQNKQSPLYP----GMLYVP 245
           L       P  P    L  + P  ++  +++      PM P  ++SP+ P      L+ P
Sbjct: 545 LSPPFEESPLSPPPEELPTSPPPEAS--RLSPPPEESPMSPPPEESPMSPPPEASRLFPP 602

Query: 246 FGANQLNAPARLGIMSSEEVAGGREDPMAYGAMFPGFGGMRPGFEGMPHNPAMGGDFTLE 305
           F  + L+ P     +S    A     P       P    M P  E  P +P    + +  
Sbjct: 603 FEESPLSPPPEESPLSPPPEASRLSPP-------PEDSPMSPPPEESPMSPP--PEVSRL 653

Query: 306 FDSPVAATKGPENEEGGAQGSPMPEANPDNLENPAFLTELEPAPHAGLLALPKDDIPGLP 365
              PV +   P  EE     SP PE +P +   P   + L P P     + P +D P  P
Sbjct: 654 SPLPVVSRLSPPPEESPL--SPPPEESPTS--PPPEASRLSPPPEDSPTSPPPEDSPASP 709

Query: 366 RSPSGKMKGLP----SVTPAAADPLMTP 389
             P   +  LP     + P   +P + P
Sbjct: 710 -PPEDSLMSLPLEESPLLPLPEEPQLCP 736



 Score = 37.0 bits (84), Expect = 0.036
 Identities = 93/389 (23%), Positives = 133/389 (34%), Gaps = 63/389 (16%)

Query: 80   LPPHSSLPWMRPREHETQQYEYSLPVHPPPLPSQPSLKPQ-----------QPGLKPFLQ 128
            L P +  P + P+  E      +   H  P+P +P L PQ           +P L P  +
Sbjct: 788  LSPQAEGPHLSPQPEELHLSPQTEEPHLSPVPEEPCLSPQPEESHLSPQSEEPCLSPRPE 847

Query: 129  SA--AATTNQATALKEALQPPIHLGHLPLQEGELPLVQQQVAPSDKP----PKPELPGVD 182
             +  +    +        +PP   G  P  E ELPL      PS  P    P    PG  
Sbjct: 848  ESHLSPELEKPPLSPRPEKPPEEPGQCPAPE-ELPLFPPPGEPSLSPLLGEPALSEPGEP 906

Query: 183  FADPQGPSLPGMDFPDPQ-GPSLPGLDFADPQGSTIFQIARLISHGPMPQNKQSPLYPGM 241
               P    LP     +P   P L   D   P  S I   A   +  P+          G 
Sbjct: 907  PLSPLPEELPLSPSGEPSLSPQLMPPDPLPPPLSPIITAAAPPALSPL----------GE 956

Query: 242  LYVPFGA-------NQLNAPARLGIMSSEEVAGGREDPMAYGAMFPGFGGMRPGFEGMPH 294
            L  PFGA       + L AP  L    S        DP     M      + P   G P 
Sbjct: 957  LEYPFGAKGDSDPESPLAAPI-LETPISPPPEANCTDPEPVPPM------ILPPSPGSPV 1009

Query: 295  NPAMGGDFTLEFDSPVAATKGPENEEGGAQGSPMPEANPDNLENPAFLTELEPAPHAGL- 353
             PA          SP+     P       Q S +P+ +P +  +P  L    P+P + + 
Sbjct: 1010 GPA----------SPILMEPLPPQCSPLLQHSLVPQNSPPSQCSPPALPLSVPSPLSPIG 1059

Query: 354  LALPKDDIPGLPRSPSGKMK--GLPSVTPAAADPLMTPELADVYRTYDADMTTSVDF--- 408
              +   D   L    + K+     P++ P+A  PL +P + D+     +      DF   
Sbjct: 1060 KVVGVSDEAELHEMETEKVSEPECPALEPSATSPLPSP-MGDLSCPAPSPAPALDDFSGL 1118

Query: 409  -QEEATMDTTMAPNSLQT--SMPGNKAQE 434
             ++ A +D   AP S       PG+ A E
Sbjct: 1119 GEDTAPLDGIDAPGSQPEPGQTPGSLASE 1147



 Score = 36.2 bits (82), Expect = 0.062
 Identities = 68/289 (23%), Positives = 99/289 (34%), Gaps = 46/289 (15%)

Query: 115 SLKPQQPGLKPFLQSAAATTNQATALKEALQPPIH--LGHLPLQEGELPLVQQQVAPSDK 172
           S++P++PG  P    A         L+  L+ P++  +  LP  E E PL      P + 
Sbjct: 403 SMQPKEPG--PLQCEAKPLGKAGVQLEPQLEAPLNEEMPLLPPPE-ESPL---SPPPEES 456

Query: 173 PPKPELPGVDFADPQGPSLPGMDFPD-----------PQGPSLPGLDFADPQGSTIFQIA 221
           P  P  P      P    LP    P+           P  P       + P  S+ F   
Sbjct: 457 PTSPP-PEASRLSPPPEELPASPLPEALHLSRPLEESPLSPPPEESPLSPPPESSPFSPL 515

Query: 222 RLISHGPMPQNKQSPLYPGMLYVPFGANQLNAPARLGIMSS--EEVAGGREDPMAYGAMF 279
                 P  ++  SP     L  P  A+ L+ P     +S   EE+        +  +  
Sbjct: 516 EESPLSPPEESPPSPALETPLSPPPEASPLSPPFEESPLSPPPEELPTSPPPEASRLSPP 575

Query: 280 PGFGGMRPGFEGMPHNPAMGGDFTLEFDSPVAATKGPENEEGGAQGSPMPEANPDNLENP 339
           P    M P  E  P +P            P A+   P  EE     SP PE +P      
Sbjct: 576 PEESPMSPPPEESPMSPP-----------PEASRLFPPFEESPL--SPPPEESP------ 616

Query: 340 AFLTELEPAPHAGLLALPKDDIPGLPRSPSGKMKGLPSVTPAAADPLMT 388
                L P P A  L+ P +D P  P      M   P V+  +  P+++
Sbjct: 617 -----LSPPPEASRLSPPPEDSPMSPPPEESPMSPPPEVSRLSPLPVVS 660



 Score = 34.7 bits (78), Expect = 0.18
 Identities = 73/335 (21%), Positives = 98/335 (29%), Gaps = 55/335 (16%)

Query: 102  SLPVHPPPLPSQPSLKPQQPGLKPFLQSAAATTNQATALKEALQPPIHLGHLPLQEGEL- 160
            +L +  PP P      P       F+ S       +T+    L+PP      P   GEL 
Sbjct: 2101 ALHLRIPPQPGALGSPPPAAAPTIFIGSPTTPAGLSTSADGFLKPPAGSVPGPDSPGELF 2160

Query: 161  ----PLVQQQVAPSDK-------PPKPELPGVDFADPQGPSLPGMDFPDPQ-------GP 202
                P V  QV   D        P +P  P      P  PS  G     P        G 
Sbjct: 2161 LKLPPQVPAQVPSQDPFGLAPAYPLEPRFPTAPPTYPPYPSPTGAPAQPPMLGASSRPGA 2220

Query: 203  SLPGLDFADPQGSTIFQIAR----LISHGPMPQNKQSPLYPGMLYVPFGANQLNAPARLG 258
              PG     P G+   Q +     L    P   N   P  PG+     G  + + P    
Sbjct: 2221 GQPGEFHTTPPGTPRHQPSTPDPFLKPRCPSLDNLAVPESPGV-----GGGKASEPLLSP 2275

Query: 259  IMSSEEVAGGREDPMAYGAMFPGFGGMRPGFEGMPHNPAMGGDFTLE----FDSPVAATK 314
                E            GA  P +G    GF   P +    G   L+    F +P+    
Sbjct: 2276 PPFGESRKALEVKKEELGASSPSYGPPNLGFVDSPSSGTHLGGLELKTPDVFKAPLTPRA 2335

Query: 315  GPENEEGGAQG------------SPMPEANPDNLE---------NPAFLTELEPAPHAGL 353
                 +    G            +P P ++PD             P      +P P    
Sbjct: 2336 SQVEPQSPGLGLRPQEPPPAQALAPSPPSHPDIFRPGSYTDPYAQPPLTPRPQPPPPESC 2395

Query: 354  LALPKDDIPGLP--RSPSGKMKGLPSVTPAAADPL 386
             ALP   +P  P  R P+       S +P    PL
Sbjct: 2396 CALPPRSLPSDPFSRVPASPQSQSSSQSPLTPRPL 2430



 Score = 32.0 bits (71), Expect = 1.2
 Identities = 31/104 (29%), Positives = 41/104 (39%), Gaps = 13/104 (12%)

Query: 104  PVHPPPLPSQPSLKPQQPGLKPFLQSAAATTNQATALKEALQPPIHLGHLPLQEGELPLV 163
            PVHP P PS P  +P++P   P   S   T        EA  PP H G    Q   L   
Sbjct: 4304 PVHPTPPPSSPQ-EPKRPSQLPSPSSQLPT--------EAQLPPTHPGTPKPQGPTLEPP 4354

Query: 164  QQQVAPSDKPPKPELPGVDFADPQGPSLPGMDFPDPQGPSLPGL 207
              +V+P+      +L    F+   GP  P  +  + Q P    L
Sbjct: 4355 PGRVSPA----AAQLADTLFSKGLGPWDPPDNLAETQKPEQSSL 4394



 Score = 29.3 bits (64), Expect = 7.6
 Identities = 36/153 (23%), Positives = 53/153 (34%), Gaps = 26/153 (16%)

Query: 80  LPPHSSLPWMRPREHETQQYEYSLPVHPPPLPSQPSL--KPQQPGLKPFLQSAAATTN-Q 136
           L P    P + PR  E      +   H  P P +P L   P++P L P  +    +   +
Sbjct: 743 LSPRPEEPHLSPRPEEPHLSPQAEEPHLSPQPEEPCLCAVPEEPHLSPQAEGPHLSPQPE 802

Query: 137 ATALKEALQPPIHLGHLPLQ--------------EGELPLVQQQVAPSDKPPKPELPGVD 182
              L    + P HL  +P +              + E P +  +   S   P+ E P + 
Sbjct: 803 ELHLSPQTEEP-HLSPVPEEPCLSPQPEESHLSPQSEEPCLSPRPEESHLSPELEKPPLS 861

Query: 183 FADPQGPSLPGMD--------FPDPQGPSLPGL 207
               + P  PG          FP P  PSL  L
Sbjct: 862 PRPEKPPEEPGQCPAPEELPLFPPPGEPSLSPL 894


>gi|149999378 inverted formin 2 isoform 2 [Homo sapiens]
          Length = 1240

 Score = 49.3 bits (116), Expect = 7e-06
 Identities = 46/130 (35%), Positives = 54/130 (41%), Gaps = 19/130 (14%)

Query: 84  SSLPWMRPREHETQQYEYSLPVHPPPLPSQPSLKPQQPGLKPFLQSAAATTNQATALKEA 143
           S L   +PR  E QQ     P  PPPL    S +P  P   P L S  A      AL  A
Sbjct: 404 SILKVSQPRALE-QQASTPPPPPPPPLLPGSSAEPPPPPPPPPLPSVGAK-----ALPTA 457

Query: 144 LQPPIHLGHLPLQEGELPLVQQQVAPSDKPPKPELPG-VDFADPQGPSLPGMDFPDPQGP 202
             PP            LP +   +AP   P  P LPG  +F  P  P LPG+  P P  P
Sbjct: 458 PPPP-----------PLPGLGA-MAPPAPPLPPPLPGSCEFLPPPPPPLPGLGCPPPPPP 505

Query: 203 SLPGLDFADP 212
            LPG+ +  P
Sbjct: 506 LLPGMGWGPP 515


>gi|149999380 inverted formin 2 isoform 1 [Homo sapiens]
          Length = 1249

 Score = 49.3 bits (116), Expect = 7e-06
 Identities = 46/130 (35%), Positives = 54/130 (41%), Gaps = 19/130 (14%)

Query: 84  SSLPWMRPREHETQQYEYSLPVHPPPLPSQPSLKPQQPGLKPFLQSAAATTNQATALKEA 143
           S L   +PR  E QQ     P  PPPL    S +P  P   P L S  A      AL  A
Sbjct: 404 SILKVSQPRALE-QQASTPPPPPPPPLLPGSSAEPPPPPPPPPLPSVGAK-----ALPTA 457

Query: 144 LQPPIHLGHLPLQEGELPLVQQQVAPSDKPPKPELPG-VDFADPQGPSLPGMDFPDPQGP 202
             PP            LP +   +AP   P  P LPG  +F  P  P LPG+  P P  P
Sbjct: 458 PPPP-----------PLPGLGA-MAPPAPPLPPPLPGSCEFLPPPPPPLPGLGCPPPPPP 505

Query: 203 SLPGLDFADP 212
            LPG+ +  P
Sbjct: 506 LLPGMGWGPP 515


>gi|41349482 proline-rich protein BstNI subfamily 1 isoform 1
           preproprotein [Homo sapiens]
          Length = 331

 Score = 49.3 bits (116), Expect = 7e-06
 Identities = 75/279 (26%), Positives = 88/279 (31%), Gaps = 58/279 (20%)

Query: 104 PVHPPPLPSQPSLKPQQPGLKPFLQSAAATTNQATALKEALQPPIHLGHLPLQEGELPLV 163
           P  PPP P +P   P Q G +P                +  + P      P  + + P  
Sbjct: 108 PQGPPPPPGKPQGPPPQGGNRPQGPPPPGKPQGPPPQGDKSRSP----RSPPGKPQGPPP 163

Query: 164 QQQVAPSDKPPKPELPGVDFADPQGPSLPGMDFPDPQGPSLPGLDFADPQGSTIFQIARL 223
           Q    P   PP P         PQGP  P      PQGP  PG     PQG         
Sbjct: 164 QGGNQPQGPPPPP-------GKPQGP--PPQGGKKPQGPPPPG----KPQGPP------- 203

Query: 224 ISHGPMPQNKQSPLYPGMLYVPFGANQLNAPARLGIMSSEEVAGGREDPMAYGAMFPGFG 283
              G   ++ QSP        P G NQ   P            G  + P   G   P  G
Sbjct: 204 -PQGDKSRSSQSPPGKPQGPPPQGGNQPQGPP--------PPPGKPQGPPPQGGNKPQ-G 253

Query: 284 GMRPGFEGMPHNPAMGGDFTLEFDSPVAATKGPENEEGGAQGSPMPEA--NPDNLENPAF 341
              PG    P  PA GG  +    SP    +GP  +EG     P P A  NP   + P  
Sbjct: 254 PPPPGKPQGP--PAQGGSKSQSARSPPGKPQGPPQQEGNNPQGPPPPAGGNPQQPQAP-- 309

Query: 342 LTELEPAPHAGLLALPKDDIPGLPRSPSGKMKGLPSVTP 380
                          P     G PR P G   G PS  P
Sbjct: 310 ---------------PAGQPQGPPRPPQG---GRPSRPP 330



 Score = 35.8 bits (81), Expect = 0.081
 Identities = 56/221 (25%), Positives = 70/221 (31%), Gaps = 45/221 (20%)

Query: 177 ELPGVDFADPQGPSLPGMDFPD-------------------PQGPSLPGLDFADPQGSTI 217
           E P +   +PQGPS  G + P                    PQGP  PG     PQG   
Sbjct: 27  ESPSLIAGNPQGPSPQGGNKPQGPPPPPGKPQGPPPQGGNKPQGPPPPG----KPQGPP- 81

Query: 218 FQIARLISHGPMPQNKQSPLYPGMLYVPFGANQLNAPARLGIMSSEEVAGGREDPMAYGA 277
                    G   ++ +SP        P G NQ   P            G  + P   G 
Sbjct: 82  -------PQGDKSRSPRSPPGKPQGPPPQGGNQPQGP--------PPPPGKPQGPPPQGG 126

Query: 278 MFPGFGGMRPGFEGMPHNPAMGGDFTLEFDSPVAATKGPENEEGG-AQGSPMPEANPDN- 335
             P      P   G P  P   GD +    SP    +GP  + G   QG P P   P   
Sbjct: 127 NRP----QGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGP 182

Query: 336 LENPAFLTELEPAPHAGLLALPKDDIPGLPRSPSGKMKGLP 376
                   +  P P       P+ D     +SP GK +G P
Sbjct: 183 PPQGGKKPQGPPPPGKPQGPPPQGDKSRSSQSPPGKPQGPP 223



 Score = 29.6 bits (65), Expect = 5.8
 Identities = 39/143 (27%), Positives = 47/143 (32%), Gaps = 21/143 (14%)

Query: 81  PPHSSLPWMRPREHETQQYEYSLPVHPPPLPSQPSLKPQQPGLKPFLQSAAATTNQATAL 140
           PP    P   P + +  +   S P  P   P Q   +PQ P   P          Q    
Sbjct: 193 PPPPGKPQGPPPQGDKSRSSQSPPGKPQGPPPQGGNQPQGPPPPP--GKPQGPPPQGGNK 250

Query: 141 KEALQPPIHLGHLPLQEGELPLVQQQVAPSDKPPKPELPGVDFADPQGPSLPGMDFP--- 197
            +   PP      P Q G     Q   +P  KP  P  P  +  +PQGP  P    P   
Sbjct: 251 PQGPPPPGKPQGPPAQGGSKS--QSARSPPGKPQGP--PQQEGNNPQGPPPPAGGNPQQP 306

Query: 198 ------DPQGPSLPGLDFADPQG 214
                  PQGP  P      PQG
Sbjct: 307 QAPPAGQPQGPPRP------PQG 323


>gi|89142735 alpha 3 type IV collagen isoform 4 precursor [Homo
            sapiens]
          Length = 1494

 Score = 47.8 bits (112), Expect = 2e-05
 Identities = 71/233 (30%), Positives = 84/233 (36%), Gaps = 50/233 (21%)

Query: 173  PPKPELPGVDFADPQGPSLPGMDFPDPQGPSLPGLDFADPQGSTIFQIARLISHGPMPQN 232
            P  P LPG       G   P      P  P  PG     P GS +  I           +
Sbjct: 1224 PGPPGLPGAIIPGQTGNRGPPGSRGSPGAPGPPG-----PPGSHVIGIKG---------D 1269

Query: 233  KQSPLYPGMLYVPFGANQLNAPARLGIMSSEEVAGGREDPMAYGAMFPGFGGMR--PGFE 290
            K S  +PG    P  A  +  P RLG   +  + G R DP   G  FPG  G +  PGF 
Sbjct: 1270 KGSMGHPGPKGPPGTAGDMGPPGRLGAPGTPGLPGPRGDPGFQG--FPGVKGEKGNPGFL 1327

Query: 291  GM--------PHNP--AMGGDFTLEFDSPVAATKGPENEEG--GAQGSPMPEANPDNLEN 338
            G         P  P    G   TL+  S +  + GP    G  G QG P P   P N   
Sbjct: 1328 GSIGPPGPIGPKGPPGVRGDPGTLKIIS-LPGSPGPPGTPGEPGMQGEPGPPGPPGN--- 1383

Query: 339  PAFLTELEPAPHAGLLALPKDDIPGLPRSPSGK-----MKGLPSVTPAAADPL 386
               L    P    G     KD  PG P  P+G+      KG P   PA +D L
Sbjct: 1384 ---LGPCGPRGKPG-----KDGKPGTP-GPAGEKGNKGSKGEPG--PAGSDGL 1425



 Score = 36.2 bits (82), Expect = 0.062
 Identities = 81/344 (23%), Positives = 105/344 (30%), Gaps = 92/344 (26%)

Query: 28  PFFPQQSGTPGMASLSLETMR---QLGSLQRLNTLSQYSRYGFGKSFNSLWMHGLLPPHS 84
           P FP   G PG+     ET++   Q+G         Q  R G      +  + GL  P  
Sbjct: 525 PGFPGAQGDPGLKGEKGETLQPEGQVGVPGDPGLRGQPGRKGLDGIPGTPGVKGLPGPKG 584

Query: 85  SLPWMRPREHETQQYEYSLPVHPPPL--PSQPSLKPQ-QPGLKPFLQSAAATTNQATALK 141
            L     +  +    +   P  P P      P   PQ +PGL+               + 
Sbjct: 585 ELALSGEKGDQGPPGDPGSPGSPGPAGPAGPPGYGPQGEPGLQG-----------TQGVP 633

Query: 142 EALQPPIHLGHLPLQEGELPLVQQQVAPSDKPPKPELPGVD----------------FAD 185
            A  PP   G      GEL +      P   P  P  PG                     
Sbjct: 634 GAPGPPGEAG----PRGELSVSTPVPGPPGPPGPPGHPGPQGPPGIPGSLGKCGDPGLPG 689

Query: 186 PQG-PSLPGMDFPDPQGPSLPGLDFADPQGSTIFQIARLISHGPMPQNKQSPLYPGMLYV 244
           P G P +PG+ FP P GP          QG               P  K S   PG +  
Sbjct: 690 PDGEPGIPGIGFPGPPGPK-------GDQG--------------FPGTKGSLGCPGKMGE 728

Query: 245 PFGANQLNAPARLGIMSSEEVAGGREDP---MAYGAMFPGFGGMRP--------GFEGMP 293
           P            G+     + G + +P   M  G   PGF G R         G  G+P
Sbjct: 729 P------------GLPGKPGLPGAKGEPAVAMPGGPGTPGFPGERGNSGEHGEIGLPGLP 776

Query: 294 HNPAMGGDFTLEFDSPVAATKGPENEEG----------GAQGSP 327
             P   G+  L+         GP  E+G          GAQG P
Sbjct: 777 GLPGTPGNEGLDGPRGDPGQPGPPGEQGPPGRCIEGPRGAQGLP 820


>gi|89142733 alpha 3 type IV collagen isoform 2 precursor [Homo
            sapiens]
          Length = 1637

 Score = 47.8 bits (112), Expect = 2e-05
 Identities = 71/233 (30%), Positives = 84/233 (36%), Gaps = 50/233 (21%)

Query: 173  PPKPELPGVDFADPQGPSLPGMDFPDPQGPSLPGLDFADPQGSTIFQIARLISHGPMPQN 232
            P  P LPG       G   P      P  P  PG     P GS +  I           +
Sbjct: 1224 PGPPGLPGAIIPGQTGNRGPPGSRGSPGAPGPPG-----PPGSHVIGIKG---------D 1269

Query: 233  KQSPLYPGMLYVPFGANQLNAPARLGIMSSEEVAGGREDPMAYGAMFPGFGGMR--PGFE 290
            K S  +PG    P  A  +  P RLG   +  + G R DP   G  FPG  G +  PGF 
Sbjct: 1270 KGSMGHPGPKGPPGTAGDMGPPGRLGAPGTPGLPGPRGDPGFQG--FPGVKGEKGNPGFL 1327

Query: 291  GM--------PHNP--AMGGDFTLEFDSPVAATKGPENEEG--GAQGSPMPEANPDNLEN 338
            G         P  P    G   TL+  S +  + GP    G  G QG P P   P N   
Sbjct: 1328 GSIGPPGPIGPKGPPGVRGDPGTLKIIS-LPGSPGPPGTPGEPGMQGEPGPPGPPGN--- 1383

Query: 339  PAFLTELEPAPHAGLLALPKDDIPGLPRSPSGK-----MKGLPSVTPAAADPL 386
               L    P    G     KD  PG P  P+G+      KG P   PA +D L
Sbjct: 1384 ---LGPCGPRGKPG-----KDGKPGTP-GPAGEKGNKGSKGEPG--PAGSDGL 1425



 Score = 36.2 bits (82), Expect = 0.062
 Identities = 81/344 (23%), Positives = 105/344 (30%), Gaps = 92/344 (26%)

Query: 28  PFFPQQSGTPGMASLSLETMR---QLGSLQRLNTLSQYSRYGFGKSFNSLWMHGLLPPHS 84
           P FP   G PG+     ET++   Q+G         Q  R G      +  + GL  P  
Sbjct: 525 PGFPGAQGDPGLKGEKGETLQPEGQVGVPGDPGLRGQPGRKGLDGIPGTPGVKGLPGPKG 584

Query: 85  SLPWMRPREHETQQYEYSLPVHPPPL--PSQPSLKPQ-QPGLKPFLQSAAATTNQATALK 141
            L     +  +    +   P  P P      P   PQ +PGL+               + 
Sbjct: 585 ELALSGEKGDQGPPGDPGSPGSPGPAGPAGPPGYGPQGEPGLQG-----------TQGVP 633

Query: 142 EALQPPIHLGHLPLQEGELPLVQQQVAPSDKPPKPELPGVD----------------FAD 185
            A  PP   G      GEL +      P   P  P  PG                     
Sbjct: 634 GAPGPPGEAG----PRGELSVSTPVPGPPGPPGPPGHPGPQGPPGIPGSLGKCGDPGLPG 689

Query: 186 PQG-PSLPGMDFPDPQGPSLPGLDFADPQGSTIFQIARLISHGPMPQNKQSPLYPGMLYV 244
           P G P +PG+ FP P GP          QG               P  K S   PG +  
Sbjct: 690 PDGEPGIPGIGFPGPPGPK-------GDQG--------------FPGTKGSLGCPGKMGE 728

Query: 245 PFGANQLNAPARLGIMSSEEVAGGREDP---MAYGAMFPGFGGMRP--------GFEGMP 293
           P            G+     + G + +P   M  G   PGF G R         G  G+P
Sbjct: 729 P------------GLPGKPGLPGAKGEPAVAMPGGPGTPGFPGERGNSGEHGEIGLPGLP 776

Query: 294 HNPAMGGDFTLEFDSPVAATKGPENEEG----------GAQGSP 327
             P   G+  L+         GP  E+G          GAQG P
Sbjct: 777 GLPGTPGNEGLDGPRGDPGQPGPPGEQGPPGRCIEGPRGAQGLP 820


>gi|89142730 alpha 3 type IV collagen isoform 1 precursor [Homo
            sapiens]
          Length = 1670

 Score = 47.8 bits (112), Expect = 2e-05
 Identities = 71/233 (30%), Positives = 84/233 (36%), Gaps = 50/233 (21%)

Query: 173  PPKPELPGVDFADPQGPSLPGMDFPDPQGPSLPGLDFADPQGSTIFQIARLISHGPMPQN 232
            P  P LPG       G   P      P  P  PG     P GS +  I           +
Sbjct: 1224 PGPPGLPGAIIPGQTGNRGPPGSRGSPGAPGPPG-----PPGSHVIGIKG---------D 1269

Query: 233  KQSPLYPGMLYVPFGANQLNAPARLGIMSSEEVAGGREDPMAYGAMFPGFGGMR--PGFE 290
            K S  +PG    P  A  +  P RLG   +  + G R DP   G  FPG  G +  PGF 
Sbjct: 1270 KGSMGHPGPKGPPGTAGDMGPPGRLGAPGTPGLPGPRGDPGFQG--FPGVKGEKGNPGFL 1327

Query: 291  GM--------PHNP--AMGGDFTLEFDSPVAATKGPENEEG--GAQGSPMPEANPDNLEN 338
            G         P  P    G   TL+  S +  + GP    G  G QG P P   P N   
Sbjct: 1328 GSIGPPGPIGPKGPPGVRGDPGTLKIIS-LPGSPGPPGTPGEPGMQGEPGPPGPPGN--- 1383

Query: 339  PAFLTELEPAPHAGLLALPKDDIPGLPRSPSGK-----MKGLPSVTPAAADPL 386
               L    P    G     KD  PG P  P+G+      KG P   PA +D L
Sbjct: 1384 ---LGPCGPRGKPG-----KDGKPGTP-GPAGEKGNKGSKGEPG--PAGSDGL 1425



 Score = 36.2 bits (82), Expect = 0.062
 Identities = 81/344 (23%), Positives = 105/344 (30%), Gaps = 92/344 (26%)

Query: 28  PFFPQQSGTPGMASLSLETMR---QLGSLQRLNTLSQYSRYGFGKSFNSLWMHGLLPPHS 84
           P FP   G PG+     ET++   Q+G         Q  R G      +  + GL  P  
Sbjct: 525 PGFPGAQGDPGLKGEKGETLQPEGQVGVPGDPGLRGQPGRKGLDGIPGTPGVKGLPGPKG 584

Query: 85  SLPWMRPREHETQQYEYSLPVHPPPL--PSQPSLKPQ-QPGLKPFLQSAAATTNQATALK 141
            L     +  +    +   P  P P      P   PQ +PGL+               + 
Sbjct: 585 ELALSGEKGDQGPPGDPGSPGSPGPAGPAGPPGYGPQGEPGLQG-----------TQGVP 633

Query: 142 EALQPPIHLGHLPLQEGELPLVQQQVAPSDKPPKPELPGVD----------------FAD 185
            A  PP   G      GEL +      P   P  P  PG                     
Sbjct: 634 GAPGPPGEAG----PRGELSVSTPVPGPPGPPGPPGHPGPQGPPGIPGSLGKCGDPGLPG 689

Query: 186 PQG-PSLPGMDFPDPQGPSLPGLDFADPQGSTIFQIARLISHGPMPQNKQSPLYPGMLYV 244
           P G P +PG+ FP P GP          QG               P  K S   PG +  
Sbjct: 690 PDGEPGIPGIGFPGPPGPK-------GDQG--------------FPGTKGSLGCPGKMGE 728

Query: 245 PFGANQLNAPARLGIMSSEEVAGGREDP---MAYGAMFPGFGGMRP--------GFEGMP 293
           P            G+     + G + +P   M  G   PGF G R         G  G+P
Sbjct: 729 P------------GLPGKPGLPGAKGEPAVAMPGGPGTPGFPGERGNSGEHGEIGLPGLP 776

Query: 294 HNPAMGGDFTLEFDSPVAATKGPENEEG----------GAQGSP 327
             P   G+  L+         GP  E+G          GAQG P
Sbjct: 777 GLPGTPGNEGLDGPRGDPGQPGPPGEQGPPGRCIEGPRGAQGLP 820


>gi|210032580 SET domain containing 1B [Homo sapiens]
          Length = 1923

 Score = 47.0 bits (110), Expect = 4e-05
 Identities = 76/329 (23%), Positives = 110/329 (33%), Gaps = 62/329 (18%)

Query: 91   PREHETQQYEYSLPVHPPPLPSQPSLKPQQPGLKPFLQSAAATTNQATALKEALQPPIHL 150
            P E  +   E  LPV     P+     P++PGL    + A   + +  A +   +PP+  
Sbjct: 1200 PEERPSMLDEPPLPVGVEE-PADSREPPEEPGLSQ--EGAMLLSPEPPAKEVEARPPLSP 1256

Query: 151  GHLPLQEGE--------LPLVQQQVAPSDKPPKPELPGVD--FADPQGPSLPGMDFPDPQ 200
               P  + E        LPL  Q   P  +PP+P  P  +    D   PS+P     +  
Sbjct: 1257 ERAPEHDLEVEPEPPMMLPLPLQPPLPPPRPPRPPSPPPEPETTDASHPSVPPEPLAEDH 1316

Query: 201  GPSLPGLDFADPQGSTIFQIARLISHGPMPQNKQSPLYPGMLYVPFGANQLNAPARLGIM 260
             P  PGL                   G + +++ +   P     P G   L+  +    +
Sbjct: 1317 PPHTPGL------------------CGSLAKSQSTETVPA---TPGGEPPLSGGSSGLSL 1355

Query: 261  SSEEVAGGREDPMAYGAMFPGFGGMRPGFEGMPHNPAMGGDFTLEFDSP--------VAA 312
            SS +V G    P +Y A  P          G+P  P     FT  F  P           
Sbjct: 1356 SSPQVPG---SPFSYPAPSPSLSS-----GGLPRTPGRDFSFTPTFSEPSGPLLLPVCPL 1407

Query: 313  TKGPENEEGGAQGS----------PMPEANPDNLENPAFL--TELEPAPHAGLLALPKDD 360
              G  +E  G   S          P+P   P  L  PA L      P P   LL  P   
Sbjct: 1408 PTGRRDERSGPLASPVLLETGLPLPLPLPLPLPLALPAVLRAQARAPTPLPPLLPAPLAS 1467

Query: 361  IPGLPRSPSGKMKGLPSVTPAAADPLMTP 389
             P   +   G+ +  P    +   PL+ P
Sbjct: 1468 CPPPMKRKPGRPRRSPPSMLSLDGPLVRP 1496



 Score = 32.7 bits (73), Expect = 0.69
 Identities = 30/97 (30%), Positives = 41/97 (42%), Gaps = 8/97 (8%)

Query: 103  LPVHPPPLPSQPSLKPQQPGLKPFLQSAAATTNQATALKEALQPPIHLGHLPLQEGELPL 162
            +P  PPPLP QP   P  P ++P         NQ  +  EA+ PP   G   + E  + L
Sbjct: 1536 IPAPPPPLPPQPPPPPPPPPVEPTKLPFKELDNQWPS--EAI-PPGPRGRDEVTEEYMEL 1592

Query: 163  VQQQVAPSDKPPKPELPGVDFADPQGPSLPGMDFPDP 199
             + +  P  +PPK      D   P G   P +  P P
Sbjct: 1593 AKSR-GPWRRPPKKR--HEDLVPPAGS--PELSPPQP 1624


>gi|89142737 alpha 3 type IV collagen isoform 5 precursor [Homo
            sapiens]
          Length = 1424

 Score = 46.6 bits (109), Expect = 5e-05
 Identities = 55/178 (30%), Positives = 65/178 (36%), Gaps = 31/178 (17%)

Query: 173  PPKPELPGVDFADPQGPSLPGMDFPDPQGPSLPGLDFADPQGSTIFQIARLISHGPMPQN 232
            P  P LPG       G   P      P  P  PG     P GS +  I           +
Sbjct: 1224 PGPPGLPGAIIPGQTGNRGPPGSRGSPGAPGPPG-----PPGSHVIGIKG---------D 1269

Query: 233  KQSPLYPGMLYVPFGANQLNAPARLGIMSSEEVAGGREDPMAYGAMFPGFGGMR--PGFE 290
            K S  +PG    P  A  +  P RLG   +  + G R DP   G  FPG  G +  PGF 
Sbjct: 1270 KGSMGHPGPKGPPGTAGDMGPPGRLGAPGTPGLPGPRGDPGFQG--FPGVKGEKGNPGFL 1327

Query: 291  GM--------PHNP--AMGGDFTLEFDSPVAATKGPENEEG--GAQGSPMPEANPDNL 336
            G         P  P    G   TL+  S +  + GP    G  G QG P P   P NL
Sbjct: 1328 GSIGPPGPIGPKGPPGVRGDPGTLKIIS-LPGSPGPPGTPGEPGMQGEPGPPGPPGNL 1384



 Score = 36.2 bits (82), Expect = 0.062
 Identities = 81/344 (23%), Positives = 105/344 (30%), Gaps = 92/344 (26%)

Query: 28  PFFPQQSGTPGMASLSLETMR---QLGSLQRLNTLSQYSRYGFGKSFNSLWMHGLLPPHS 84
           P FP   G PG+     ET++   Q+G         Q  R G      +  + GL  P  
Sbjct: 525 PGFPGAQGDPGLKGEKGETLQPEGQVGVPGDPGLRGQPGRKGLDGIPGTPGVKGLPGPKG 584

Query: 85  SLPWMRPREHETQQYEYSLPVHPPPL--PSQPSLKPQ-QPGLKPFLQSAAATTNQATALK 141
            L     +  +    +   P  P P      P   PQ +PGL+               + 
Sbjct: 585 ELALSGEKGDQGPPGDPGSPGSPGPAGPAGPPGYGPQGEPGLQG-----------TQGVP 633

Query: 142 EALQPPIHLGHLPLQEGELPLVQQQVAPSDKPPKPELPGVD----------------FAD 185
            A  PP   G      GEL +      P   P  P  PG                     
Sbjct: 634 GAPGPPGEAG----PRGELSVSTPVPGPPGPPGPPGHPGPQGPPGIPGSLGKCGDPGLPG 689

Query: 186 PQG-PSLPGMDFPDPQGPSLPGLDFADPQGSTIFQIARLISHGPMPQNKQSPLYPGMLYV 244
           P G P +PG+ FP P GP          QG               P  K S   PG +  
Sbjct: 690 PDGEPGIPGIGFPGPPGPK-------GDQG--------------FPGTKGSLGCPGKMGE 728

Query: 245 PFGANQLNAPARLGIMSSEEVAGGREDP---MAYGAMFPGFGGMRP--------GFEGMP 293
           P            G+     + G + +P   M  G   PGF G R         G  G+P
Sbjct: 729 P------------GLPGKPGLPGAKGEPAVAMPGGPGTPGFPGERGNSGEHGEIGLPGLP 776

Query: 294 HNPAMGGDFTLEFDSPVAATKGPENEEG----------GAQGSP 327
             P   G+  L+         GP  E+G          GAQG P
Sbjct: 777 GLPGTPGNEGLDGPRGDPGQPGPPGEQGPPGRCIEGPRGAQGLP 820


>gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo
           sapiens]
          Length = 855

 Score = 46.2 bits (108), Expect = 6e-05
 Identities = 82/329 (24%), Positives = 108/329 (32%), Gaps = 42/329 (12%)

Query: 81  PPHSSLPWMRPREHETQQYEYSLPVH-------PPPLPSQPSLKPQQPGLKPFLQSAAAT 133
           PP S  P + P    + Q   +L VH       PPP P  P   P  P   P +  +A  
Sbjct: 411 PPAS--PPLSPLATPSPQAPNALAVHLLQAPFSPPPSP--PVQAPFSPPASPPVSPSATP 466

Query: 134 TNQATALKEALQPPIHLGHLPLQEGELPLVQQQVAPSDKPPKPELPGVDFADPQGPSLPG 193
            +QA     A  PP+ +   P      P+      P   PP    P +  A P   + P 
Sbjct: 467 PSQAPPSLAA--PPLQVP--PSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPA 522

Query: 194 MDFPDPQGPSLPGLDFADPQGSTIFQIARLISHGPM---PQNKQSPLYPGMLYVPFG--- 247
           +  P  Q    P   F    G   F  +  +   P+   P      L   +L VP     
Sbjct: 523 LATPPLQALPSPPASFP---GQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPA 579

Query: 248 ANQLNAPARLGIMSSEEVAGGREDPMAYGAMFPGFGGMRPGFEGMPHNPAMGGDFTLEFD 307
           +  L AP R      +    G   P    A+ PG     P     P +   G D      
Sbjct: 580 SPTLQAPRRPPTPGPDTSVSG---PRLTLALAPG---PPPPPSRSPSSTLSGPDLAGHSS 633

Query: 308 SPVAATKGPEN-------EEGGAQGSPMPEANPDNLENPAFLTELEPAPHAGLLALPKDD 360
           S   AT  PE         EGGA  SP P+A        A+     PAP       P   
Sbjct: 634 S---ATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAW--SRGPAPPLAFRGAPGAP 688

Query: 361 IPGLPRSPSGKMKGLPSVTPAAADPLMTP 389
           +P  P +  G   GL ++         TP
Sbjct: 689 LPWPPATGPGSADGLCTIYETEGPESATP 717



 Score = 35.0 bits (79), Expect = 0.14
 Identities = 66/299 (22%), Positives = 91/299 (30%), Gaps = 39/299 (13%)

Query: 90  RPREHETQQYEYSLPVHPPPLPSQPSLKPQQPGLKPFLQSAAATTNQATALKEALQPPIH 149
           R   H +Q     L    PP  + P  K   P L P   S  AT + + AL+    P   
Sbjct: 264 RAPAHPSQPKPKGLQALRPPQVTPPR-KDAAPALGPLSSSPLATPSPSAALQSQAPPT-- 320

Query: 150 LGHLPLQEGELPLVQQQVAPSD-KPPKPELPGVDFADPQGPSLPGMDFPDPQGPSLPGLD 208
              LP       L  Q   P    PP P  P         PSL  +    P  P+ P   
Sbjct: 321 ---LPATPHSSSLTCQLATPLPLAPPSPSAP---------PSLQTL----PSPPATPPSQ 364

Query: 209 FADPQGSTIFQIARLISHGP--MPQNKQSPLYPGMLYVPFGANQLNAPARLGIMSSEEVA 266
                GS   Q        P   P     P  P  L +P      + PA   +      +
Sbjct: 365 ATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPS 424

Query: 267 GGREDPMAYGAMFPGFGGMRPGFEGMPHNPAMGGDFTLEFDSPVAATKGPENEEGGAQGS 326
               + +A   +   F          P +P +   F+     PV+ +  P ++   +  +
Sbjct: 425 PQAPNALAVHLLQAPFSP--------PPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAA 476

Query: 327 PMPEANPDNLENPAFLTELEPAPHAGLLALPKDDIPGLPRSPSGKMKGLPSVTPAAADP 385
           P  +  P    +P       P P A          P L   P    K  P   PA A P
Sbjct: 477 PPLQVPPSPPASPPMSPSATPPPQAP---------PPLAAPPLQLAKPPPQAPPALATP 526


>gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo
           sapiens]
          Length = 816

 Score = 46.2 bits (108), Expect = 6e-05
 Identities = 82/329 (24%), Positives = 108/329 (32%), Gaps = 42/329 (12%)

Query: 81  PPHSSLPWMRPREHETQQYEYSLPVH-------PPPLPSQPSLKPQQPGLKPFLQSAAAT 133
           PP S  P + P    + Q   +L VH       PPP P  P   P  P   P +  +A  
Sbjct: 372 PPAS--PPLSPLATPSPQAPNALAVHLLQAPFSPPPSP--PVQAPFSPPASPPVSPSATP 427

Query: 134 TNQATALKEALQPPIHLGHLPLQEGELPLVQQQVAPSDKPPKPELPGVDFADPQGPSLPG 193
            +QA     A  PP+ +   P      P+      P   PP    P +  A P   + P 
Sbjct: 428 PSQAPPSLAA--PPLQVP--PSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPA 483

Query: 194 MDFPDPQGPSLPGLDFADPQGSTIFQIARLISHGPM---PQNKQSPLYPGMLYVPFG--- 247
           +  P  Q    P   F    G   F  +  +   P+   P      L   +L VP     
Sbjct: 484 LATPPLQALPSPPASFP---GQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPA 540

Query: 248 ANQLNAPARLGIMSSEEVAGGREDPMAYGAMFPGFGGMRPGFEGMPHNPAMGGDFTLEFD 307
           +  L AP R      +    G   P    A+ PG     P     P +   G D      
Sbjct: 541 SPTLQAPRRPPTPGPDTSVSG---PRLTLALAPG---PPPPPSRSPSSTLSGPDLAGHSS 594

Query: 308 SPVAATKGPEN-------EEGGAQGSPMPEANPDNLENPAFLTELEPAPHAGLLALPKDD 360
           S   AT  PE         EGGA  SP P+A        A+     PAP       P   
Sbjct: 595 S---ATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAW--SRGPAPPLAFRGAPGAP 649

Query: 361 IPGLPRSPSGKMKGLPSVTPAAADPLMTP 389
           +P  P +  G   GL ++         TP
Sbjct: 650 LPWPPATGPGSADGLCTIYETEGPESATP 678



 Score = 32.0 bits (71), Expect = 1.2
 Identities = 66/313 (21%), Positives = 97/313 (30%), Gaps = 31/313 (9%)

Query: 87  PWMRPREHETQQYEYSLPVHPPPLPSQPSLKP--QQPGLKPFLQSAAATTNQATALKEAL 144
           P   PR+  +   E+S     P    +PS     Q+P  +    SA   ++ A +   A 
Sbjct: 192 PTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSAR 251

Query: 145 QPPIHLGH--LPLQEGELPLVQQQVAPSDKPPKPELPGVDFAD--------PQGPSLPGM 194
             P    H   P  +G   L   QV P  K   P L  +  +         P  PS P  
Sbjct: 252 GTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAPPSPSAPPS 311

Query: 195 DFPDPQGPSLPGLDFADPQGSTIFQIARLISHGP--MPQNKQSPLYPGMLYVPFGANQLN 252
               P  P+ P        GS   Q        P   P     P  P  L +P      +
Sbjct: 312 LQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPS 371

Query: 253 APARLGIMSSEEVAGGREDPMAYGAMFPGFGGMRPGFEGMPHNPAMGGDFTLEFDSPVAA 312
            PA   +      +    + +A   +   F          P +P +   F+     PV+ 
Sbjct: 372 PPASPPLSPLATPSPQAPNALAVHLLQAPFSP--------PPSPPVQAPFSPPASPPVSP 423

Query: 313 TKGPENEEGGAQGSPMPEANPDNLENPAFLTELEPAPHAGLLALPKDDIPGLPRSPSGKM 372
           +  P ++   +  +P  +  P    +P       P P A          P L   P    
Sbjct: 424 SATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAP---------PPLAAPPLQLA 474

Query: 373 KGLPSVTPAAADP 385
           K  P   PA A P
Sbjct: 475 KPPPQAPPALATP 487


>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo
           sapiens]
          Length = 1124

 Score = 43.9 bits (102), Expect = 3e-04
 Identities = 92/352 (26%), Positives = 118/352 (33%), Gaps = 53/352 (15%)

Query: 72  NSLWMHGLLPPHSSLPWMRPREHETQQYEYSLPVHPPPLPSQPSLKPQQPGLK-PFLQ-- 128
           N+L +H L  P S      P      Q  +S P  PP  PS        P L  P LQ  
Sbjct: 654 NALAVHLLQAPFS------PPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVP 707

Query: 129 -SAAATTNQATALKEALQPPIHLGHLPLQEGELPLVQQQVAPSDKPPKPELPGVDFADP- 186
            S  A+   + +     Q P  L   PLQ    P     ++PS  PP P +P +  A P 
Sbjct: 708 PSPPASPPMSPSATPPPQAPPPLAAPPLQVPPSPPASPPMSPSATPP-PRVPPLLAAPPL 766

Query: 187 QGPSLPGMDF-------PDPQGP---------SLPGLDFADPQGSTIFQIARLISHGPM- 229
           Q P  P           P PQ P         +LP    + P G   F  +  +   P+ 
Sbjct: 767 QVPPSPPASLPMSPLAKPPPQAPPALATPPLQALPSPPASFP-GQAPFSPSASLPMSPLA 825

Query: 230 --PQNKQSPLYPGMLYV---PFGANQLNAPARLGIMSSEEVAGGREDPMAYGAMFPGFGG 284
             P      L   +L V   P  +  L AP R      +    G   P    A+ P   G
Sbjct: 826 TPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSG---PRLTLALAP---G 879

Query: 285 MRPGFEGMPHNPAMGGDFTLEFDSPVAATKGPE-------NEEGGAQGSPMPEANPDNLE 337
             P     P +   G D      S   AT  PE         EGGA  SP P+A      
Sbjct: 880 PPPPPSRSPSSTLSGPDLAGHSSS---ATSTPEELRGYDSGPEGGAAASPPPDAELAACH 936

Query: 338 NPAFLTELEPAPHAGLLALPKDDIPGLPRSPSGKMKGLPSVTPAAADPLMTP 389
             A+     PAP       P   +P  P +  G   GL ++         TP
Sbjct: 937 PAAW--SRGPAPPLAFRGAPGAPLPWPPATGPGSADGLCTIYETEGPESATP 986


>gi|33356556 amelogenin (X chromosome) isoform 3 precursor [Homo
           sapiens]
          Length = 205

 Score = 43.9 bits (102), Expect = 3e-04
 Identities = 53/192 (27%), Positives = 72/192 (37%), Gaps = 20/192 (10%)

Query: 15  ILILCLLEMSFAVPFFPQQSGTPGMASLSLETMR-QLGSLQR----LNTLSQYSRY---- 65
           IL  CLL  +FA+P  P   G PG  + S E    Q  ++ R    L  L  Y       
Sbjct: 5   ILFACLLGAAFAMPL-PPHPGHPGYINFSYENSHSQAINVDRTALVLTPLKWYQSIRPPY 63

Query: 66  -GFGKSFNSLWMHGLLPPHSSLPWMRPREHETQQYEYSLPVHPPPLPSQPSLKPQQPGLK 124
             +G      W+H  + P   L    P  H  Q +      H P +P+Q  + PQQP + 
Sbjct: 64  PSYGYEPMGGWLHHQIIP--VLSQQHPPTHTLQPHH-----HIPVVPAQQPVIPQQPMMP 116

Query: 125 -PFLQSAAATTNQATALKEALQPPIHLGHLPLQEGELPLVQQQVAPSDK-PPKPELPGVD 182
            P   S     +    L    Q P     +  Q  +    Q  V P    PP+P LP + 
Sbjct: 117 VPGQHSMTPIQHHQPNLPPPAQQPYQPQPVQPQPHQPMQPQPPVHPMQPLPPQPPLPPMF 176

Query: 183 FADPQGPSLPGM 194
              P  P LP +
Sbjct: 177 PMQPLPPMLPDL 188


>gi|163965366 nascent polypeptide-associated complex alpha subunit
            isoform a [Homo sapiens]
          Length = 2078

 Score = 43.9 bits (102), Expect = 3e-04
 Identities = 79/304 (25%), Positives = 96/304 (31%), Gaps = 61/304 (20%)

Query: 104  PVHPPPLPSQPSLKPQQPGLKPFLQSAAATTNQATALKEALQPPIHLGHLPLQEGELPLV 163
            P  P   P  P   P  P  K      AAT       K  L  P H G         P  
Sbjct: 1080 PTPPAATPPSPKGGPATPSPKGAPMPPAATPPSP---KGGLATPPHKG--------APTT 1128

Query: 164  QQQVAPSDK-----PPKPELPGVDFADPQGPSLPGMDFPDPQG-PSLPGLDFADPQGSTI 217
                 PS K     PP    P    A P  P   G+  P P+G P+ P      P+G   
Sbjct: 1129 PAATPPSPKGGLATPPPKGAPTTPAATPPSPK-GGLATPPPKGAPTTPAATPPSPKGGLA 1187

Query: 218  FQIARLISHGPMPQNKQSPLYPGMLYVPFGANQLNAPARLGIMSSEEVAGGREDPMAYGA 277
                        P  K +P  P              P+  G +++    G    P A   
Sbjct: 1188 -----------TPSPKGAPTTPAA----------TPPSPKGGLATPSPKGAPTTPAATPP 1226

Query: 278  MFPGFGGMRPGFEGMPHNPAM------GGDFTLE---FDSPVAATKGPENEEGGAQGSPM 328
              P  G   P  +G P  PA       GG  T       +P AAT  P + +GG    P 
Sbjct: 1227 S-PKGGLATPSPKGAPTTPAATPPSPKGGPATPPPKGAPTPPAAT--PPSLKGGLATPPH 1283

Query: 329  PEANPDNLENPAFLTELEPAPHAGLLALPKDDIPGLPRSPSGKMKGLPSVTP---AAADP 385
              A      NPA +T   P+P  G    P    P  P +     KG P   P   A   P
Sbjct: 1284 KGA-----PNPAVVTP--PSPKGGPATSPPKGAPTPPAATPPSPKGSPGTPPPKGAPTPP 1336

Query: 386  LMTP 389
             +TP
Sbjct: 1337 AVTP 1340



 Score = 41.2 bits (95), Expect = 0.002
 Identities = 82/323 (25%), Positives = 115/323 (35%), Gaps = 60/323 (18%)

Query: 102  SLPVHPPPLPSQPSLK-PQQPGLKPFLQSAAATTNQATALKEALQPPIHLG--HLPLQEG 158
            +LP    P PS  +L  P++    P  + A A +  +++ K+A   P   G    P  +G
Sbjct: 879  TLPPKETPTPSVVNLPFPKEGPATPAPKQAPALSMTSSSPKKARATPAPKGIPASPSPKG 938

Query: 159  ELPLVQQQVAPSDKPPKPELPGVDFADPQGPSLPGMDFPDPQG-PSLPGLDFADPQGSTI 217
                      P+  PP P+      +    P+ P    P P+G P+ P      P+G+  
Sbjct: 939  A------PTPPAATPPSPKGGPATPSPKWAPTPPAATPPSPKGGPATPS-----PKGAPT 987

Query: 218  FQIARLISHGPMPQNKQSPLYPGMLYVPFGANQLNAPARLGIMSSEEVAGGREDPMAYGA 277
               A        P  K  P  P     P     +  P+  G  ++     G   P A   
Sbjct: 988  PPAAT------PPSPKGGPATPSPKGAPTPP-AVTPPSPKGSPAATPFPKGASTPPAATP 1040

Query: 278  MFP-GFGGMRPGFEGMPHNPAM------GGDFTLEFD---SPVAATKGPENEEGGA---- 323
              P G     P  +G P  PA       GG  T       +P AAT  P + +GG     
Sbjct: 1041 PSPKGSPAATPLPKGAPTTPAATLPSPKGGPATPSLKGAPTPPAAT--PPSPKGGPATPS 1098

Query: 324  -QGSPMPEA-----------NPDNLENPAFLTELEPAPHAGLLALPKDDIP----GLPRS 367
             +G+PMP A            P +   P       P+P  GL   P    P      P S
Sbjct: 1099 PKGAPMPPAATPPSPKGGLATPPHKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPS 1158

Query: 368  PSGKM-----KGLPSVTPAAADP 385
            P G +     KG P+ TPAA  P
Sbjct: 1159 PKGGLATPPPKGAPT-TPAATPP 1180



 Score = 40.4 bits (93), Expect = 0.003
 Identities = 80/309 (25%), Positives = 103/309 (33%), Gaps = 60/309 (19%)

Query: 104  PVHPPP--LPSQPSLKPQQPGLKPFLQSAAATTNQATALKEALQPPIHLGH---LPLQEG 158
            P  P P   P+ P++ P  P   P    AA    +  +   A  PP   G     PL +G
Sbjct: 1000 PATPSPKGAPTPPAVTPPSPKGSP----AATPFPKGASTPPAATPPSPKGSPAATPLPKG 1055

Query: 159  ELPLVQQQVAPSDK--PPKPELPGVDFADPQGPSLPGMDFPDPQG-PSLPGLDFADPQGS 215
              P       PS K  P  P L G        P+ P    P P+G P+ P      P+G+
Sbjct: 1056 A-PTTPAATLPSPKGGPATPSLKGA-------PTPPAATPPSPKGGPATPS-----PKGA 1102

Query: 216  TIFQIARLISHGPMPQNKQSPLYPGMLYVPFGANQLNAPARL-----GIMSSEEVAGGRE 270
                        PMP     P   G L  P        PA       G +++    G   
Sbjct: 1103 ------------PMPPAATPPSPKGGLATPPHKGAPTTPAATPPSPKGGLATPPPKGAPT 1150

Query: 271  DPMAYGAMFPGFGGMRPGFEGMPHNPAM------GGDFTLE-FDSPVAATKGPENEEGGA 323
             P A     P  G   P  +G P  PA       GG  T     +P      P + +GG 
Sbjct: 1151 TPAATPPS-PKGGLATPPPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGL 1209

Query: 324  QGSPMPEANPDNLENPAFLTELEPAPHAGLLALPKDDIPGLPRSPSGKMKGLPSVTP--- 380
              +P P+  P     PA      P+P  GL        P  P +     KG P+  P   
Sbjct: 1210 -ATPSPKGAPTT---PA---ATPPSPKGGLATPSPKGAPTTPAATPPSPKGGPATPPPKG 1262

Query: 381  AAADPLMTP 389
            A   P  TP
Sbjct: 1263 APTPPAATP 1271



 Score = 33.5 bits (75), Expect = 0.40
 Identities = 73/308 (23%), Positives = 97/308 (31%), Gaps = 41/308 (13%)

Query: 109  PLPSQPSLKPQQPGLKPFLQSAAATTNQATALKEALQPPIHLGHLPLQEGELPLVQQQVA 168
            P P   S+ PQ    +P  +  +A  +       +   P+    LP  E  L     + +
Sbjct: 794  PSPLGVSVSPQTK--RPPTKKGSAGPDTPIGNLSSPVSPVEASFLP--ENSLSFQGSKDS 849

Query: 169  P----SDKPPKPELPGVDFA----DPQGPSLPGMDFPDPQGPSLPGLDFADPQGSTIFQI 220
            P    S  PP P+      A     P+G +LP  + P P   +LP      P      Q 
Sbjct: 850  PATTHSPTPPSPKGAPTPSAVTPLSPKGVTLPPKETPTPSVVNLP-FPKEGPATPAPKQA 908

Query: 221  ARLISHGPMPQNKQSPLYPGMLYVPFGANQLNAPARLGIMSSEEVAG-------GREDPM 273
              L      P  K++   P    +P   +   AP            G           P 
Sbjct: 909  PALSMTSSSP--KKARATPAPKGIPASPSPKGAPTPPAATPPSPKGGPATPSPKWAPTPP 966

Query: 274  AYGAMFPGFGGMRPGFEGMPHNPA------MGGDFTLEFDSPVAATKGPENEEGGAQGSP 327
            A     P  G   P  +G P  PA       GG  T    SP  A   P       +GSP
Sbjct: 967  AATPPSPKGGPATPSPKGAPTPPAATPPSPKGGPAT---PSPKGAPTPPAVTPPSPKGSP 1023

Query: 328  MPEANPDNLENPAFLTELEPAPHAGLLALPKDDIPGLPRSPSGKM---KG---LPSVTPA 381
                 P     P   T   P        LPK    G P +P+  +   KG    PS+  A
Sbjct: 1024 AATPFPKGASTPPAATPPSPKGSPAATPLPK----GAPTTPAATLPSPKGGPATPSLKGA 1079

Query: 382  AADPLMTP 389
               P  TP
Sbjct: 1080 PTPPAATP 1087


>gi|239754955 PREDICTED: similar to COL22A1 protein [Homo sapiens]
          Length = 1073

 Score = 43.1 bits (100), Expect = 5e-04
 Identities = 68/246 (27%), Positives = 82/246 (33%), Gaps = 66/246 (26%)

Query: 179 PGVDFADPQGPSLPGMDFPDPQGPSLPGLDFADPQGSTIFQ-IARLISHGPMPQ------ 231
           PG+  A P GPS P  D   P    LPG  F  PQG      ++ L+S G +        
Sbjct: 504 PGIGVAGPPGPSGPPGDKGSPGSRGLPG--FPGPQGPAGRDGLSSLLSPGDINLLAKDVC 561

Query: 232 NKQSPLYPGMLYVPFGANQLNAPARLGIMSSEEVAGGREDPMAYGAMFPGFGGMR----- 286
           N   P  PG+  +P        P + G   +E   G    P   G   PG  G +     
Sbjct: 562 NDCPPGPPGLPGLPGFKGDKGVPGKPGREGTEGKKGEAGPPGLPGP--PGIAGPQGSQGE 619

Query: 287 ------------------PGFEGMPHNPAMGGDFTLEFDSPVAATKGPENEEGGAQGSPM 328
                             PGF G P NP   G         +A   GP     G QGSP 
Sbjct: 620 RGADGEVGQKGDQGHPGVPGFMGPPGNPGPPG------ADGIAGAAGPP----GIQGSPG 669

Query: 329 PEANPDNLENPAFLTELEPAPHAGLLALP-------KDDIPGLPRSPSGKM--KGLPSVT 379
            E  P             P   +GL  +P       +D  PG P  P GK    GLP   
Sbjct: 670 KEGPPG------------PQGPSGLPGIPGEEGKEGRDGKPGPPGEP-GKAGEPGLPGPE 716

Query: 380 PAAADP 385
            A   P
Sbjct: 717 GARGPP 722



 Score = 32.7 bits (73), Expect = 0.69
 Identities = 77/297 (25%), Positives = 103/297 (34%), Gaps = 70/297 (23%)

Query: 114 PSLKPQQPGLKPFLQSAAATTNQATALKEAL---QPPIHLGHLPLQEGELPLVQQQVAPS 170
           P   P  PG      +A     Q +  KE     Q P  L  +P +EG+     +   P 
Sbjct: 643 PPGNPGPPGADGIAGAAGPPGIQGSPGKEGPPGPQGPSGLPGIPGEEGKEGRDGKPGPPG 702

Query: 171 D--KPPKPELPGVDFADPQGPSLPGMD-------FPDPQGPS----LPGLD-FADPQGST 216
           +  K  +P LPG + A  +GP  PG          P P+G S    LPG +      G T
Sbjct: 703 EPGKAGEPGLPGPEGA--RGP--PGFKGHTGDSGAPGPRGESGAMGLPGQEGLPGKDGDT 758

Query: 217 IFQIARLISHGPM-PQNKQSPLYPGMLYVPFGANQLNAPARLGIMSSEEVAGGREDPMAY 275
                     GP  PQ  Q P  P     P       +P   G   +    G + +  + 
Sbjct: 759 ----------GPTGPQGPQGPRGP-----PGKNGSPGSPGEPGPSGTPGQKGSKGENGSP 803

Query: 276 GAMFPGFGGMR-----------PGFEGMPHNPAMGGDFTLEFDSPVAATKGPENEEGGAQ 324
           G   PGF G R           PG EG+P  P   G      D  +   KGP     G +
Sbjct: 804 G--LPGFLGPRGPPGEPGEKGVPGKEGVPGKPGEPGFKGERGDPGIKGDKGPP----GGK 857

Query: 325 GSPMPEANPDNLENPAFLTELEPAPHAGLL---ALPKDDIPGLPRSPSGKMKGLPSV 378
           G P     P +              H GL+    LP ++ P  P  P G+  G P +
Sbjct: 858 GQPGDPGIPGH------------KGHTGLMGPQGLPGENGPVGPPGPPGQ-PGFPGL 901


>gi|15890086 type IV collagen alpha 5 isoform 2 precursor [Homo
           sapiens]
          Length = 1691

 Score = 43.1 bits (100), Expect = 5e-04
 Identities = 90/321 (28%), Positives = 106/321 (33%), Gaps = 68/321 (21%)

Query: 107 PPPLPSQPSLKPQQPGLKPFLQSAAATTNQATALKEALQPPIHLGHLPLQEGELPLVQQQ 166
           PP  P  P L P  PG   F         QA A       P  L  +P   G       +
Sbjct: 492 PPGQPGLPGL-PGPPGSLGF-PGQKGEKGQAGATG-----PKGLPGIPGAPGAPGFPGSK 544

Query: 167 VAPSDKPPKPELPGV--DFADPQGPSLPGMD-FPDPQG-PSLPGLDFADPQGSTIFQIAR 222
             P D    P + G   +   P  P LPG+   P   G P LPG    +P G T F+  R
Sbjct: 545 GEPGDILTFPGMKGDKGELGSPGAPGLPGLPGTPGQDGLPGLPGPK-GEPGGIT-FKGER 602

Query: 223 LISHGPMPQNKQSPLYPGMLYVPFGANQLNAPARLGIMSSEEVAGGREDPMAYGAMF-PG 281
               GP P N   P  PG +  P G      P  +G    + VAG    P   G    PG
Sbjct: 603 ----GP-PGNPGLPGLPGNIG-PMGPPGFGPPGPVGEKGIQGVAGNPGQPGIPGPKGDPG 656

Query: 282 FGGMRPGFEGMPHNPAMGGDFTLEFDS--------------------PVAATKGPENEEG 321
               +PG  G+P NP   GD  L  D                     P     GP   +G
Sbjct: 657 QTITQPGKPGLPGNPGRDGDVGLPGDPGLPGQPGLPGIPGSKGEPGIPGIGLPGPPGPKG 716

Query: 322 -----------------GAQGSPMPEANPDNLENPAFLTELEPAP-----HAGLLALPKD 359
                            G +G P P   P     P F     P P       G L  PK 
Sbjct: 717 FPGIPGPPGAPGTPGRIGLEGPPGPPGFPGPKGEPGFALPGPPGPPGLPGFKGALG-PKG 775

Query: 360 D--IPGLPRSPSGK--MKGLP 376
           D   PG P  P G+  + GLP
Sbjct: 776 DRGFPG-PPGPPGRTGLDGLP 795



 Score = 31.6 bits (70), Expect = 1.5
 Identities = 63/252 (25%), Positives = 78/252 (30%), Gaps = 71/252 (28%)

Query: 160  LPLVQQQVAPSDKPPK---PELPGVDFADPQGP----------------------SLPGM 194
            LP  +  V P+ +P     P LPG+    P GP                        PG+
Sbjct: 794  LPGPKGDVGPNGQPGPMGPPGLPGIGVQGPPGPPGIPGPIGQPGLHGIPGEKGDPGPPGL 853

Query: 195  DFPDPQG----PSLPGLDF-ADPQGSTIFQIARLISHGPMPQNKQSPLYPGMLYVPFGAN 249
            D P P G    P +PG      P GS             +P    +  +PG         
Sbjct: 854  DVPGPPGERGSPGIPGAPGPIGPPGSP-----------GLPGKAGASGFPGTKGEMGMMG 902

Query: 250  QLNAPARLGIMSSEEVAGGREDPMAYGAMFPGFGGM--RPGFEGMPHNPAMGGDFTLEFD 307
                P  LGI     V G + D    G   PG  G     G +G P  P   G      D
Sbjct: 903  PPGPPGPLGIPGRSGVPGLKGDDGLQGQ--PGLPGPTGEKGSKGEPGLPGPPG----PMD 956

Query: 308  SPVAATKGPENEEG-----------GAQGSPMPEANPDNLENPAFLTELEPAPHAGLLAL 356
              +  +KG + E G           G QG P     P     P       P P       
Sbjct: 957  PNLLGSKGEKGEPGLPGIPGVSGPKGYQGLPGDPGQPGLSGQPGL-----PGPPG----- 1006

Query: 357  PKDDIPGLPRSP 368
            PK + PGLP  P
Sbjct: 1007 PKGN-PGLPGQP 1017



 Score = 30.8 bits (68), Expect = 2.6
 Identities = 32/114 (28%), Positives = 39/114 (34%), Gaps = 25/114 (21%)

Query: 280 PGFGGMR-----PGFEGMPHNPAMGGDFTLEFDSPVAATKGPENEEG--------GAQGS 326
           PG  G+R     PGF G P  P M G         +    G + E G        G QG 
Sbjct: 86  PGPKGIRGPPGLPGFPGTPGLPGMPGHDGAPGPQGIPGCNGTKGERGFPGSPGFPGLQGP 145

Query: 327 PMPEANPDNLENP-AFLTELEPAPHAGLLALPKDDIPGLPRSPSGKMKGLPSVT 379
           P P   P     P + +    P P            PG P  P   ++GLP  T
Sbjct: 146 PGPPGIPGMKGEPGSIIMSSLPGPKGN---------PGYPGPPG--IQGLPGPT 188


>gi|4502955 type IV collagen alpha 5 isoform 1 precursor [Homo
           sapiens]
          Length = 1685

 Score = 43.1 bits (100), Expect = 5e-04
 Identities = 90/321 (28%), Positives = 106/321 (33%), Gaps = 68/321 (21%)

Query: 107 PPPLPSQPSLKPQQPGLKPFLQSAAATTNQATALKEALQPPIHLGHLPLQEGELPLVQQQ 166
           PP  P  P L P  PG   F         QA A       P  L  +P   G       +
Sbjct: 492 PPGQPGLPGL-PGPPGSLGF-PGQKGEKGQAGATG-----PKGLPGIPGAPGAPGFPGSK 544

Query: 167 VAPSDKPPKPELPGV--DFADPQGPSLPGMD-FPDPQG-PSLPGLDFADPQGSTIFQIAR 222
             P D    P + G   +   P  P LPG+   P   G P LPG    +P G T F+  R
Sbjct: 545 GEPGDILTFPGMKGDKGELGSPGAPGLPGLPGTPGQDGLPGLPGPK-GEPGGIT-FKGER 602

Query: 223 LISHGPMPQNKQSPLYPGMLYVPFGANQLNAPARLGIMSSEEVAGGREDPMAYGAMF-PG 281
               GP P N   P  PG +  P G      P  +G    + VAG    P   G    PG
Sbjct: 603 ----GP-PGNPGLPGLPGNIG-PMGPPGFGPPGPVGEKGIQGVAGNPGQPGIPGPKGDPG 656

Query: 282 FGGMRPGFEGMPHNPAMGGDFTLEFDS--------------------PVAATKGPENEEG 321
               +PG  G+P NP   GD  L  D                     P     GP   +G
Sbjct: 657 QTITQPGKPGLPGNPGRDGDVGLPGDPGLPGQPGLPGIPGSKGEPGIPGIGLPGPPGPKG 716

Query: 322 -----------------GAQGSPMPEANPDNLENPAFLTELEPAP-----HAGLLALPKD 359
                            G +G P P   P     P F     P P       G L  PK 
Sbjct: 717 FPGIPGPPGAPGTPGRIGLEGPPGPPGFPGPKGEPGFALPGPPGPPGLPGFKGALG-PKG 775

Query: 360 D--IPGLPRSPSGK--MKGLP 376
           D   PG P  P G+  + GLP
Sbjct: 776 DRGFPG-PPGPPGRTGLDGLP 795



 Score = 31.6 bits (70), Expect = 1.5
 Identities = 63/252 (25%), Positives = 78/252 (30%), Gaps = 71/252 (28%)

Query: 160  LPLVQQQVAPSDKPPK---PELPGVDFADPQGP----------------------SLPGM 194
            LP  +  V P+ +P     P LPG+    P GP                        PG+
Sbjct: 794  LPGPKGDVGPNGQPGPMGPPGLPGIGVQGPPGPPGIPGPIGQPGLHGIPGEKGDPGPPGL 853

Query: 195  DFPDPQG----PSLPGLDF-ADPQGSTIFQIARLISHGPMPQNKQSPLYPGMLYVPFGAN 249
            D P P G    P +PG      P GS             +P    +  +PG         
Sbjct: 854  DVPGPPGERGSPGIPGAPGPIGPPGSP-----------GLPGKAGASGFPGTKGEMGMMG 902

Query: 250  QLNAPARLGIMSSEEVAGGREDPMAYGAMFPGFGGM--RPGFEGMPHNPAMGGDFTLEFD 307
                P  LGI     V G + D    G   PG  G     G +G P  P   G      D
Sbjct: 903  PPGPPGPLGIPGRSGVPGLKGDDGLQGQ--PGLPGPTGEKGSKGEPGLPGPPG----PMD 956

Query: 308  SPVAATKGPENEEG-----------GAQGSPMPEANPDNLENPAFLTELEPAPHAGLLAL 356
              +  +KG + E G           G QG P     P     P       P P       
Sbjct: 957  PNLLGSKGEKGEPGLPGIPGVSGPKGYQGLPGDPGQPGLSGQPGL-----PGPPG----- 1006

Query: 357  PKDDIPGLPRSP 368
            PK + PGLP  P
Sbjct: 1007 PKGN-PGLPGQP 1017



 Score = 30.8 bits (68), Expect = 2.6
 Identities = 32/114 (28%), Positives = 39/114 (34%), Gaps = 25/114 (21%)

Query: 280 PGFGGMR-----PGFEGMPHNPAMGGDFTLEFDSPVAATKGPENEEG--------GAQGS 326
           PG  G+R     PGF G P  P M G         +    G + E G        G QG 
Sbjct: 86  PGPKGIRGPPGLPGFPGTPGLPGMPGHDGAPGPQGIPGCNGTKGERGFPGSPGFPGLQGP 145

Query: 327 PMPEANPDNLENP-AFLTELEPAPHAGLLALPKDDIPGLPRSPSGKMKGLPSVT 379
           P P   P     P + +    P P            PG P  P   ++GLP  T
Sbjct: 146 PGPPGIPGMKGEPGSIIMSSLPGPKGN---------PGYPGPPG--IQGLPGPT 188


>gi|15890088 type IV collagen alpha 5 isoform 3 precursor [Homo
           sapiens]
          Length = 1688

 Score = 43.1 bits (100), Expect = 5e-04
 Identities = 90/321 (28%), Positives = 106/321 (33%), Gaps = 68/321 (21%)

Query: 107 PPPLPSQPSLKPQQPGLKPFLQSAAATTNQATALKEALQPPIHLGHLPLQEGELPLVQQQ 166
           PP  P  P L P  PG   F         QA A       P  L  +P   G       +
Sbjct: 492 PPGQPGLPGL-PGPPGSLGF-PGQKGEKGQAGATG-----PKGLPGIPGAPGAPGFPGSK 544

Query: 167 VAPSDKPPKPELPGV--DFADPQGPSLPGMD-FPDPQG-PSLPGLDFADPQGSTIFQIAR 222
             P D    P + G   +   P  P LPG+   P   G P LPG    +P G T F+  R
Sbjct: 545 GEPGDILTFPGMKGDKGELGSPGAPGLPGLPGTPGQDGLPGLPGPK-GEPGGIT-FKGER 602

Query: 223 LISHGPMPQNKQSPLYPGMLYVPFGANQLNAPARLGIMSSEEVAGGREDPMAYGAMF-PG 281
               GP P N   P  PG +  P G      P  +G    + VAG    P   G    PG
Sbjct: 603 ----GP-PGNPGLPGLPGNIG-PMGPPGFGPPGPVGEKGIQGVAGNPGQPGIPGPKGDPG 656

Query: 282 FGGMRPGFEGMPHNPAMGGDFTLEFDS--------------------PVAATKGPENEEG 321
               +PG  G+P NP   GD  L  D                     P     GP   +G
Sbjct: 657 QTITQPGKPGLPGNPGRDGDVGLPGDPGLPGQPGLPGIPGSKGEPGIPGIGLPGPPGPKG 716

Query: 322 -----------------GAQGSPMPEANPDNLENPAFLTELEPAP-----HAGLLALPKD 359
                            G +G P P   P     P F     P P       G L  PK 
Sbjct: 717 FPGIPGPPGAPGTPGRIGLEGPPGPPGFPGPKGEPGFALPGPPGPPGLPGFKGALG-PKG 775

Query: 360 D--IPGLPRSPSGK--MKGLP 376
           D   PG P  P G+  + GLP
Sbjct: 776 DRGFPG-PPGPPGRTGLDGLP 795



 Score = 31.6 bits (70), Expect = 1.5
 Identities = 63/252 (25%), Positives = 78/252 (30%), Gaps = 71/252 (28%)

Query: 160  LPLVQQQVAPSDKPPK---PELPGVDFADPQGP----------------------SLPGM 194
            LP  +  V P+ +P     P LPG+    P GP                        PG+
Sbjct: 794  LPGPKGDVGPNGQPGPMGPPGLPGIGVQGPPGPPGIPGPIGQPGLHGIPGEKGDPGPPGL 853

Query: 195  DFPDPQG----PSLPGLDF-ADPQGSTIFQIARLISHGPMPQNKQSPLYPGMLYVPFGAN 249
            D P P G    P +PG      P GS             +P    +  +PG         
Sbjct: 854  DVPGPPGERGSPGIPGAPGPIGPPGSP-----------GLPGKAGASGFPGTKGEMGMMG 902

Query: 250  QLNAPARLGIMSSEEVAGGREDPMAYGAMFPGFGGM--RPGFEGMPHNPAMGGDFTLEFD 307
                P  LGI     V G + D    G   PG  G     G +G P  P   G      D
Sbjct: 903  PPGPPGPLGIPGRSGVPGLKGDDGLQGQ--PGLPGPTGEKGSKGEPGLPGPPG----PMD 956

Query: 308  SPVAATKGPENEEG-----------GAQGSPMPEANPDNLENPAFLTELEPAPHAGLLAL 356
              +  +KG + E G           G QG P     P     P       P P       
Sbjct: 957  PNLLGSKGEKGEPGLPGIPGVSGPKGYQGLPGDPGQPGLSGQPGL-----PGPPG----- 1006

Query: 357  PKDDIPGLPRSP 368
            PK + PGLP  P
Sbjct: 1007 PKGN-PGLPGQP 1017



 Score = 30.8 bits (68), Expect = 2.6
 Identities = 32/114 (28%), Positives = 39/114 (34%), Gaps = 25/114 (21%)

Query: 280 PGFGGMR-----PGFEGMPHNPAMGGDFTLEFDSPVAATKGPENEEG--------GAQGS 326
           PG  G+R     PGF G P  P M G         +    G + E G        G QG 
Sbjct: 86  PGPKGIRGPPGLPGFPGTPGLPGMPGHDGAPGPQGIPGCNGTKGERGFPGSPGFPGLQGP 145

Query: 327 PMPEANPDNLENP-AFLTELEPAPHAGLLALPKDDIPGLPRSPSGKMKGLPSVT 379
           P P   P     P + +    P P            PG P  P   ++GLP  T
Sbjct: 146 PGPPGIPGMKGEPGSIIMSSLPGPKGN---------PGYPGPPG--IQGLPGPT 188


>gi|51477700 mediator complex subunit 15 isoform a [Homo sapiens]
          Length = 788

 Score = 43.1 bits (100), Expect = 5e-04
 Identities = 30/92 (32%), Positives = 39/92 (42%), Gaps = 12/92 (13%)

Query: 81  PPHSSLPWMRPREHETQQYEYSLPVHPPPLPSQPSLKPQQPGLKPFLQSAAATTNQATAL 140
           PP  +LP    + H TQ ++      PPP P QP +   QP   P         +QA AL
Sbjct: 281 PPSQALPQQLQQMHHTQHHQ------PPPQPQQPPVAQNQPSQLPPQSQTQPLVSQAQAL 334

Query: 141 KEAL---QPPIHLGHLPL---QEGELPLVQQQ 166
              +   QPP+     P+   Q    P VQQQ
Sbjct: 335 PGQMLYTQPPLKFVRAPMVVQQPPVQPQVQQQ 366


>gi|32698936 B-cell CLL/lymphoma 9-like [Homo sapiens]
          Length = 1499

 Score = 43.1 bits (100), Expect = 5e-04
 Identities = 72/304 (23%), Positives = 109/304 (35%), Gaps = 56/304 (18%)

Query: 104  PVHPPPLPSQPSLK-PQQPGLKPFLQSAAATTNQATALKEALQPPIH---LGHLPLQEGE 159
            P +PP     PSL     P   P     +    Q +        P++   +  +   + E
Sbjct: 1057 PANPPSGLMNPSLPFTSSPDPTPSQNPLSLMMTQMSKYAMPSSTPLYHNAIKTIATSDDE 1116

Query: 160  LPLVQQQVAPSDKPPKPELPGVDFADPQGPSLPGMDFPDPQGPSLPGLD--FADPQGSTI 217
            L L  + + P   PP+   PG+  + P    L       P G +LPG      +P  + +
Sbjct: 1117 L-LPDRPLLPPPPPPQGSGPGISNSQPSQMHLNSAAAQSPMGMNLPGQQPLSHEPPPAML 1175

Query: 218  FQIARLISHGPMPQNKQ---SPLYPGMLYVPFGANQLNAPARLGIMSSEEVAGGREDPMA 274
                 L S+ P+  N Q    P    M+  P G + LNAP      SS+ +         
Sbjct: 1176 PSPTPLGSNIPLHPNAQGTGGPPQNSMMMAPGGPDSLNAPCGPVPSSSQMMPFPPRLQQP 1235

Query: 275  YGAMFPGFGGMRPGFEGMPHNPAMGGDFTLEFDSPVAATKGPENEEGGAQGSPMPEANPD 334
            +GAM P  GG              GG              GP  ++    G  +P   P+
Sbjct: 1236 HGAMAPTGGG--------------GG--------------GPGLQQHYPSGMALP---PE 1264

Query: 335  NLENPAFLTELEPAPHAGLLALPKDDIPGLPRSPSGKMKGL--PSVTPAAADPLMTPELA 392
            +L N        P P       P+  + G  ++ +G+M     P V P  A  L  PEL+
Sbjct: 1265 DLPNQ------PPGPMP-----PQQHLMG--KAMAGRMGDAYPPGVLPGVASVLNDPELS 1311

Query: 393  DVYR 396
            +V R
Sbjct: 1312 EVIR 1315


>gi|56243590 WD repeat domain 33 isoform 1 [Homo sapiens]
          Length = 1336

 Score = 43.1 bits (100), Expect = 5e-04
 Identities = 71/276 (25%), Positives = 96/276 (34%), Gaps = 39/276 (14%)

Query: 105 VHPPPLPSQPSLKPQQ-PGLKPFLQSAAATTNQATALKEALQPPIHLGHL--PLQEGEL- 160
           + PPP    P L PQ  PG  P  Q              + Q P+++  +  P  +G+  
Sbjct: 572 IQPPPSSGTPLLGPQPFPGQGPMSQIPQGFQQP----HPSQQMPMNMAQMGPPGPQGQFR 627

Query: 161 -PLVQQQVAPSDKPPKPELPGVD-FADPQGPSLPGMDFPDPQGPSLPGLDFADPQGSTIF 218
            P  Q Q+ P   P      G   F  PQGP  P    P PQ       D   PQG    
Sbjct: 628 PPGPQGQMGPQGPPLHQGGGGPQGFMGPQGPQGPPQGLPRPQ-------DMHGPQGMQ-- 678

Query: 219 QIARLISHGPMPQNKQSPLYPGMLYVPFG-ANQLNAPARLGIMSSEEVAGGREDPMAYGA 277
                  HGP+    Q P  P     P G       P   G +  +   G +      G 
Sbjct: 679 --RHPGPHGPL--GPQGPPGPQGSSGPQGHMGPQGPPGPQGHIGPQGPPGPQGHLGPQGP 734

Query: 278 MFPGFGGMR--PGFEGMPHNPAMGGDFTLEFDSPVAATKGPENEEGGAQGSPMPEANPDN 335
             PG  GM+  PG  GM   P   G         +    G +  +G     P+   NP  
Sbjct: 735 --PGTQGMQGPPGPRGMQGPPHPHG---------IQGGPGSQGIQGPVSQGPLMGLNPRG 783

Query: 336 LENPAFLTELE-PAPHAGLLALPKDDIPGLPRSPSG 370
           ++ P    E + PAP   ++  P  ++ G P  P G
Sbjct: 784 MQGPPGPRENQGPAPQGMIMGHPPQEMRG-PHPPGG 818


>gi|38787970 tensin like C1 domain containing phosphatase isoform 3
            [Homo sapiens]
          Length = 1285

 Score = 42.4 bits (98), Expect = 9e-04
 Identities = 77/307 (25%), Positives = 119/307 (38%), Gaps = 59/307 (19%)

Query: 83   HSSLPWMRPREHE-TQQYEYSLPVHPPPLPSQPSLKPQQPGLKPFLQSAAATTNQATALK 141
            HS+LP   PR+   +   E S P    PL +   ++ ++   +   +S  +   Q  +  
Sbjct: 763  HSTLP-RSPRDAPCSASSELSGP--STPLHTSSPVQGKESTRRQDTRSPTSAPTQRLSPG 819

Query: 142  EALQPPIHLG-----HLPLQEGELPLVQQQVAPSDKP------PKPELPG--VDFADPQG 188
            EAL P    G      LP   G  PL    V+P+  P      P+   PG   D A P+ 
Sbjct: 820  EALPPVSQAGTGKAPELPSGSGPEPLAPSPVSPTFPPSSPSDWPQERSPGGHSDGASPRS 879

Query: 189  P---SLPGMDFPDPQGPSLPGLDFADPQGSTI----FQIARLISHGPMPQNKQSPLYPGM 241
            P   +LPG+     QGP  P      P GS +     Q+  L++    PQ+  +P +P  
Sbjct: 880  PVPTTLPGLRHAPWQGPRGPP---DSPDGSPLTPVPSQMPWLVASPEPPQSSPTPAFP-- 934

Query: 242  LYVPFGANQLNAPARLGIMSSEEVAGGREDPMAYGAMFPGFGGMRPGFEG--MPHNPAMG 299
            L   +  N L+ P                 P+      PG  G +PG  G     +PA G
Sbjct: 935  LAASYDTNGLSQP-----------------PLPEKRHLPG-PGQQPGPWGPEQASSPARG 976

Query: 300  GDFTLEFDSPVAATKGPENEEGGAQGSPMPEANPDNLENPAFLTELEPAPHAG---LLAL 356
                + F +P+ +   P+  E      P  + +  N++     ++    PH      +AL
Sbjct: 977  ISHHVTF-APLLSDNVPQTPE------PPTQESQSNVKFVQDTSKFWYKPHLSRDQAIAL 1029

Query: 357  PKDDIPG 363
             KD  PG
Sbjct: 1030 LKDKDPG 1036


>gi|38787957 tensin like C1 domain containing phosphatase isoform 2
            [Homo sapiens]
          Length = 1409

 Score = 42.4 bits (98), Expect = 9e-04
 Identities = 77/307 (25%), Positives = 119/307 (38%), Gaps = 59/307 (19%)

Query: 83   HSSLPWMRPREHE-TQQYEYSLPVHPPPLPSQPSLKPQQPGLKPFLQSAAATTNQATALK 141
            HS+LP   PR+   +   E S P    PL +   ++ ++   +   +S  +   Q  +  
Sbjct: 887  HSTLP-RSPRDAPCSASSELSGP--STPLHTSSPVQGKESTRRQDTRSPTSAPTQRLSPG 943

Query: 142  EALQPPIHLG-----HLPLQEGELPLVQQQVAPSDKP------PKPELPG--VDFADPQG 188
            EAL P    G      LP   G  PL    V+P+  P      P+   PG   D A P+ 
Sbjct: 944  EALPPVSQAGTGKAPELPSGSGPEPLAPSPVSPTFPPSSPSDWPQERSPGGHSDGASPRS 1003

Query: 189  P---SLPGMDFPDPQGPSLPGLDFADPQGSTI----FQIARLISHGPMPQNKQSPLYPGM 241
            P   +LPG+     QGP  P      P GS +     Q+  L++    PQ+  +P +P  
Sbjct: 1004 PVPTTLPGLRHAPWQGPRGPP---DSPDGSPLTPVPSQMPWLVASPEPPQSSPTPAFP-- 1058

Query: 242  LYVPFGANQLNAPARLGIMSSEEVAGGREDPMAYGAMFPGFGGMRPGFEG--MPHNPAMG 299
            L   +  N L+ P                 P+      PG  G +PG  G     +PA G
Sbjct: 1059 LAASYDTNGLSQP-----------------PLPEKRHLPG-PGQQPGPWGPEQASSPARG 1100

Query: 300  GDFTLEFDSPVAATKGPENEEGGAQGSPMPEANPDNLENPAFLTELEPAPHAG---LLAL 356
                + F +P+ +   P+  E      P  + +  N++     ++    PH      +AL
Sbjct: 1101 ISHHVTF-APLLSDNVPQTPE------PPTQESQSNVKFVQDTSKFWYKPHLSRDQAIAL 1153

Query: 357  PKDDIPG 363
             KD  PG
Sbjct: 1154 LKDKDPG 1160


>gi|38787941 tensin like C1 domain containing phosphatase isoform 1
            [Homo sapiens]
          Length = 1419

 Score = 42.4 bits (98), Expect = 9e-04
 Identities = 77/307 (25%), Positives = 119/307 (38%), Gaps = 59/307 (19%)

Query: 83   HSSLPWMRPREHE-TQQYEYSLPVHPPPLPSQPSLKPQQPGLKPFLQSAAATTNQATALK 141
            HS+LP   PR+   +   E S P    PL +   ++ ++   +   +S  +   Q  +  
Sbjct: 897  HSTLP-RSPRDAPCSASSELSGP--STPLHTSSPVQGKESTRRQDTRSPTSAPTQRLSPG 953

Query: 142  EALQPPIHLG-----HLPLQEGELPLVQQQVAPSDKP------PKPELPG--VDFADPQG 188
            EAL P    G      LP   G  PL    V+P+  P      P+   PG   D A P+ 
Sbjct: 954  EALPPVSQAGTGKAPELPSGSGPEPLAPSPVSPTFPPSSPSDWPQERSPGGHSDGASPRS 1013

Query: 189  P---SLPGMDFPDPQGPSLPGLDFADPQGSTI----FQIARLISHGPMPQNKQSPLYPGM 241
            P   +LPG+     QGP  P      P GS +     Q+  L++    PQ+  +P +P  
Sbjct: 1014 PVPTTLPGLRHAPWQGPRGPP---DSPDGSPLTPVPSQMPWLVASPEPPQSSPTPAFP-- 1068

Query: 242  LYVPFGANQLNAPARLGIMSSEEVAGGREDPMAYGAMFPGFGGMRPGFEG--MPHNPAMG 299
            L   +  N L+ P                 P+      PG  G +PG  G     +PA G
Sbjct: 1069 LAASYDTNGLSQP-----------------PLPEKRHLPG-PGQQPGPWGPEQASSPARG 1110

Query: 300  GDFTLEFDSPVAATKGPENEEGGAQGSPMPEANPDNLENPAFLTELEPAPHAG---LLAL 356
                + F +P+ +   P+  E      P  + +  N++     ++    PH      +AL
Sbjct: 1111 ISHHVTF-APLLSDNVPQTPE------PPTQESQSNVKFVQDTSKFWYKPHLSRDQAIAL 1163

Query: 357  PKDDIPG 363
             KD  PG
Sbjct: 1164 LKDKDPG 1170


>gi|47132519 Ras association and pleckstrin homology domains 1
           isoform 1 [Homo sapiens]
          Length = 1250

 Score = 41.6 bits (96), Expect = 0.001
 Identities = 44/161 (27%), Positives = 56/161 (34%), Gaps = 16/161 (9%)

Query: 82  PHSSLPWMRPREHETQQYEYSLPVHPPPLPSQPSLKPQQPGLKPFLQSAAATTNQATALK 141
           P  S P    + H+ Q      P  PPP P  P+  P Q   KP +   A T+ +  A  
Sbjct: 738 PQFSAPPPPLKIHQVQHITQVAPPTPPPPPPIPAPLPPQAPPKPLVTIPAPTSTKTVA-- 795

Query: 142 EALQPPIHLGHLPLQEGELPLVQQQVA--PSDKPPKPELPGVDFADPQGPSLPGMDFPDP 199
               P +     P     +P  ++Q A   S  PP P  P V    P  P         P
Sbjct: 796 ----PVVTQAAPPTPTPPVPPAKKQPAFPASYIPPSPPTPPVPVPPPTLPKQQSFCAKPP 851

Query: 200 QGPSLPGLDFADPQGSTIFQIARLISHGPMPQNKQS-PLYP 239
             P         P  S + QIA      P P   +S PL P
Sbjct: 852 PSP-------LSPVPSVVKQIASQFPPPPTPPAMESQPLKP 885



 Score = 38.9 bits (89), Expect = 0.010
 Identities = 40/151 (26%), Positives = 53/151 (35%), Gaps = 27/151 (17%)

Query: 76  MHGLLPPHSSL-PWMRPREHETQQY---EYSLPVHPPPLPSQPSLKPQQPGLKPFLQSAA 131
           M  +  P++SL P + P+      Y   + S P+ PPP P  P   P  P   P    +A
Sbjct: 595 MESMNRPYTSLVPPLSPQPKIVTPYTASQPSPPLPPPPPPPPPPPPPPPPPPPPLPSQSA 654

Query: 132 ATTNQATALKEALQPPIHLGHLPLQEGEL------PLVQQQ-------------VAPSDK 172
            +   A  +         L +     G L      P++Q Q             V P   
Sbjct: 655 PSAGSAAPMFVKYSTITRLQNASQHSGALFKPPTPPVMQSQSVKPQILVPPNGVVPPPPP 714

Query: 173 PPKPELPGVDFAD----PQGPSLPGMDFPDP 199
           PP P  PG   A     P  PSLP    P P
Sbjct: 715 PPPPPTPGSAMAQLKPAPCAPSLPQFSAPPP 745


>gi|24308073 protein tyrosine phosphatase, non-receptor type 23 [Homo
            sapiens]
          Length = 1636

 Score = 41.6 bits (96), Expect = 0.001
 Identities = 54/199 (27%), Positives = 67/199 (33%), Gaps = 32/199 (16%)

Query: 87   PWMRPREHETQQYEYSLPVHPPPLPSQPSLKPQQPGLKPFLQSAAATTNQATALKEALQP 146
            P   P+ H +Q +    P  P PL       PQ PGL P  QS      Q   L +   P
Sbjct: 955  PQPHPQPHPSQAFGPQPPQQPLPLQHPHLFPPQAPGLLP-PQSPYPYAPQPGVLGQP-PP 1012

Query: 147  PIHL--------GHLPLQEGELPLVQQQVAPSDKPPKPELPGVDFAD-----PQGPSLPG 193
            P+H           LP   G LP       PS  PP+P  P + +       P GP    
Sbjct: 1013 PLHTQLYPGPAQDPLPAHSGALPF------PSPGPPQPPHPPLAYGPAPSTRPMGPQAAP 1066

Query: 194  MDFPDPQGPSLPGLDFADPQGSTIFQIARLISHGPMPQNKQSPLYPGMLYVPFGANQLNA 253
            +     +GPS  G     P          + S  P P     P  P     P    +  A
Sbjct: 1067 LTI---RGPSSAGQSTPSPH--------LVPSPAPSPGPGPVPPRPPAAEPPPCLRRGAA 1115

Query: 254  PARLGIMSSEEVAGGREDP 272
             A L   S E   GG + P
Sbjct: 1116 AADLLSSSPESQHGGTQSP 1134


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.314    0.134    0.410 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 22,440,387
Number of Sequences: 37866
Number of extensions: 1391295
Number of successful extensions: 6361
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 56
Number of HSP's successfully gapped in prelim test: 429
Number of HSP's that attempted gapping in prelim test: 5222
Number of HSP's gapped (non-prelim): 1329
length of query: 447
length of database: 18,247,518
effective HSP length: 105
effective length of query: 342
effective length of database: 14,271,588
effective search space: 4880883096
effective search space used: 4880883096
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 63 (28.9 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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