BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|7705915 tubulin, epsilon 1 [Homo sapiens] (475 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|7705915 tubulin, epsilon 1 [Homo sapiens] 954 0.0 gi|42558279 tubulin, beta 8 [Homo sapiens] 267 2e-71 gi|29788785 tubulin, beta [Homo sapiens] 261 1e-69 gi|4507729 tubulin, beta 2 [Homo sapiens] 260 2e-69 gi|21361322 tubulin, beta 4 [Homo sapiens] 260 2e-69 gi|5174735 tubulin, beta, 2 [Homo sapiens] 260 2e-69 gi|29788768 tubulin, beta 2B [Homo sapiens] 259 4e-69 gi|14210536 tubulin, beta 6 [Homo sapiens] 257 1e-68 gi|50592996 tubulin, beta, 4 [Homo sapiens] 255 5e-68 gi|13562114 beta tubulin 1, class VI [Homo sapiens] 245 7e-65 gi|55770868 tubulin, beta polypeptide 4, member Q [Homo sapiens] 244 1e-64 gi|17921989 tubulin, alpha 4a [Homo sapiens] 235 6e-62 gi|9507215 tubulin, alpha 8 [Homo sapiens] 234 2e-61 gi|14389309 tubulin alpha 6 [Homo sapiens] 232 5e-61 gi|57013276 tubulin, alpha, ubiquitous [Homo sapiens] 232 6e-61 gi|17986283 tubulin, alpha 1a [Homo sapiens] 230 2e-60 gi|156564363 tubulin, alpha 3d [Homo sapiens] 230 2e-60 gi|17921993 tubulin, alpha 3c [Homo sapiens] 230 2e-60 gi|46409270 tubulin, alpha 3e [Homo sapiens] 223 4e-58 gi|13376181 tubulin, alpha-like 3 [Homo sapiens] 221 1e-57 gi|31543831 tubulin, gamma 1 [Homo sapiens] 171 1e-42 gi|7706751 tubulin, gamma 2 [Homo sapiens] 170 2e-42 gi|50592998 delta-tubulin [Homo sapiens] 134 2e-31 gi|239756254 PREDICTED: similar to tubulin, beta 5 [Homo sapiens] 92 8e-19 gi|239750785 PREDICTED: similar to tubulin, beta 5 [Homo sapiens] 92 8e-19 gi|169178090 PREDICTED: similar to hCG1784562 [Homo sapiens] 59 1e-08 gi|169179398 PREDICTED: similar to hCG1784562 [Homo sapiens] 59 1e-08 gi|169181282 PREDICTED: similar to hCG1784562 [Homo sapiens] 59 1e-08 gi|94721261 2',3'-cyclic nucleotide 3' phosphodiesterase [Homo s... 32 0.96 gi|39780571 misato [Homo sapiens] 32 0.96 >gi|7705915 tubulin, epsilon 1 [Homo sapiens] Length = 475 Score = 954 bits (2465), Expect = 0.0 Identities = 475/475 (100%), Positives = 475/475 (100%) Query: 1 MTQSVVVQVGQCGNQIGCCFWDLALREHAAVNQKGIYDEAISSFFRNVDTRVVGDGGSIS 60 MTQSVVVQVGQCGNQIGCCFWDLALREHAAVNQKGIYDEAISSFFRNVDTRVVGDGGSIS Sbjct: 1 MTQSVVVQVGQCGNQIGCCFWDLALREHAAVNQKGIYDEAISSFFRNVDTRVVGDGGSIS 60 Query: 61 KGKICSLKARAVLIDMEEGVVNEILQGPLRDVFDTKQLITDISGSGNNWAVGHKVFGSLY 120 KGKICSLKARAVLIDMEEGVVNEILQGPLRDVFDTKQLITDISGSGNNWAVGHKVFGSLY Sbjct: 61 KGKICSLKARAVLIDMEEGVVNEILQGPLRDVFDTKQLITDISGSGNNWAVGHKVFGSLY 120 Query: 121 QDQILEKFRKSAEHCDCLQCFFIIHSMGGGTGSGLGTFLLKVLEDEFPEVYRFVTSIYPS 180 QDQILEKFRKSAEHCDCLQCFFIIHSMGGGTGSGLGTFLLKVLEDEFPEVYRFVTSIYPS Sbjct: 121 QDQILEKFRKSAEHCDCLQCFFIIHSMGGGTGSGLGTFLLKVLEDEFPEVYRFVTSIYPS 180 Query: 181 GEDDVITSPYNSILAMKELNEHADCVLPIDNQSLFDIISKIDLMVNSGKLGTTVKPKSLV 240 GEDDVITSPYNSILAMKELNEHADCVLPIDNQSLFDIISKIDLMVNSGKLGTTVKPKSLV Sbjct: 181 GEDDVITSPYNSILAMKELNEHADCVLPIDNQSLFDIISKIDLMVNSGKLGTTVKPKSLV 240 Query: 241 TSSSGALKKQHKKPFDAMNNIVANLLLNLTSSARFEGSLNMDLNEISMNLVPFPQLHYLV 300 TSSSGALKKQHKKPFDAMNNIVANLLLNLTSSARFEGSLNMDLNEISMNLVPFPQLHYLV Sbjct: 241 TSSSGALKKQHKKPFDAMNNIVANLLLNLTSSARFEGSLNMDLNEISMNLVPFPQLHYLV 300 Query: 301 SSLTPLYTLTDVNIPPRRLDQMFSDAFSKDHQLLRADPKHSLYLACALMVRGNVQISDLR 360 SSLTPLYTLTDVNIPPRRLDQMFSDAFSKDHQLLRADPKHSLYLACALMVRGNVQISDLR Sbjct: 301 SSLTPLYTLTDVNIPPRRLDQMFSDAFSKDHQLLRADPKHSLYLACALMVRGNVQISDLR 360 Query: 361 RNIERLKPSLQFVSWNQEGWKTSLCSVPPVGHSHSLLALANNTCVKPTFMELKERFMRLY 420 RNIERLKPSLQFVSWNQEGWKTSLCSVPPVGHSHSLLALANNTCVKPTFMELKERFMRLY Sbjct: 361 RNIERLKPSLQFVSWNQEGWKTSLCSVPPVGHSHSLLALANNTCVKPTFMELKERFMRLY 420 Query: 421 KKKAHLHHYLQVEGMEESCFTEAVSSLSALIQEYDQLDATKNMPVQDLPRLSIAM 475 KKKAHLHHYLQVEGMEESCFTEAVSSLSALIQEYDQLDATKNMPVQDLPRLSIAM Sbjct: 421 KKKAHLHHYLQVEGMEESCFTEAVSSLSALIQEYDQLDATKNMPVQDLPRLSIAM 475 >gi|42558279 tubulin, beta 8 [Homo sapiens] Length = 444 Score = 267 bits (682), Expect = 2e-71 Identities = 161/466 (34%), Positives = 245/466 (52%), Gaps = 43/466 (9%) Query: 1 MTQSVVVQVGQCGNQIGCCFWDLALREHAAVNQKGIY--DEAISSFFRNVDTRVVGDGGS 58 M + V+ Q+GQCGNQIG FW++ EHA ++ G Y D + NV G Sbjct: 1 MREIVLTQIGQCGNQIGAKFWEVISDEHA-IDSAGTYHGDSHLQLERINVYYNEASGGRY 59 Query: 59 ISKGKICSLKARAVLIDMEEGVVNEILQGPLRDVFDTKQLITDISGSGNNWAVGHKVFGS 118 + RAVL+D+E G ++ + GP VF I G+GNNWA GH G+ Sbjct: 60 VP---------RAVLVDLEPGTMDSVRSGPFGQVFRPDNFIFGQCGAGNNWAKGHYTEGA 110 Query: 119 LYQDQILEKFRKSAEHCDCLQCFFIIHSMGGGTGSGLGTFLLKVLEDEFPEVYRFVTSIY 178 + +++ RK AE CDCLQ F + HS+GGGTGSG+GT LL + +E+P+ SI Sbjct: 111 ELMESVMDVVRKEAESCDCLQGFQLTHSLGGGTGSGMGTLLLSKIREEYPDRIINTFSIL 170 Query: 179 PSGE-DDVITSPYNSILAMKELNEHADCVLPIDNQSLFDIISKIDLMVNSGKLGTTVKPK 237 PS + D + PYN+ L++ +L E+AD IDN++L+DI SK T+K Sbjct: 171 PSPKVSDTVVEPYNATLSVHQLIENADETFCIDNEALYDICSK------------TLK-- 216 Query: 238 SLVTSSSGALKKQHKKPFDAMNNIVANLLLNLTSSARFEGSLNMDLNEISMNLVPFPQLH 297 L T + G L N++V+ + +T+ RF G LN DL ++++N+VPFP+LH Sbjct: 217 -LPTPTYGDL-----------NHLVSATMSGVTTCLRFPGQLNADLRKLAVNMVPFPRLH 264 Query: 298 YLVSSLTPLYTLTDVNIPPRRLDQMFSDAFSKDHQLLRADPKHSLYLACALMVRGNVQIS 357 + + PL + + ++ F + + DP+H YL A + RG + + Sbjct: 265 FFMPGFAPLTSRGSQQYRALTVAELTQQMFDAKNMMAACDPRHGRYLTAAAIFRGRMPMR 324 Query: 358 DLRRNIERL--KPSLQFVSWNQEGWKTSLCSVPPVGHSHSLLALANNTCVKPTFMELKER 415 ++ + + K S F W KT++C +PP G S + NNT ++ F + E+ Sbjct: 325 EVDEQMFNIQDKNSSYFADWLPNNVKTAVCDIPPRGLKMSATFIGNNTAIQELFKRVSEQ 384 Query: 416 FMRLYKKKAHLHHYLQVEGMEESCFTEAVSSLSALIQEYDQL-DAT 460 F ++++KA LH Y EGM+E FTEA S+++ L+ EY Q DAT Sbjct: 385 FTAMFRRKAFLHWYTG-EGMDEMEFTEAESNMNDLVSEYQQYQDAT 429 >gi|29788785 tubulin, beta [Homo sapiens] Length = 444 Score = 261 bits (666), Expect = 1e-69 Identities = 154/466 (33%), Positives = 247/466 (53%), Gaps = 43/466 (9%) Query: 1 MTQSVVVQVGQCGNQIGCCFWDLALREHAAVNQKGIYDEAISSFFRNVDTRVVGDGGSIS 60 M + V +Q GQCGNQIG FW++ EH ++ G Y + D+ + D S+ Sbjct: 1 MREIVHIQAGQCGNQIGAKFWEVISDEHG-IDPTGTY---------HGDSDLQLDRISVY 50 Query: 61 KGKICSLK--ARAVLIDMEEGVVNEILQGPLRDVFDTKQLITDISGSGNNWAVGHKVFGS 118 + K RA+L+D+E G ++ + GP +F + SG+GNNWA GH G+ Sbjct: 51 YNEATGGKYVPRAILVDLEPGTMDSVRSGPFGQIFRPDNFVFGQSGAGNNWAKGHYTEGA 110 Query: 119 LYQDQILEKFRKSAEHCDCLQCFFIIHSMGGGTGSGLGTFLLKVLEDEFPEVYRFVTSIY 178 D +L+ RK AE CDCLQ F + HS+GGGTGSG+GT L+ + +E+P+ S+ Sbjct: 111 ELVDSVLDVVRKEAESCDCLQGFQLTHSLGGGTGSGMGTLLISKIREEYPDRIMNTFSVV 170 Query: 179 PSGE-DDVITSPYNSILAMKELNEHADCVLPIDNQSLFDIISKIDLMVNSGKLGTTVKPK 237 PS + D + PYN+ L++ +L E+ D IDN++L+DI + T+K Sbjct: 171 PSPKVSDTVVEPYNATLSVHQLVENTDETYCIDNEALYDICFR------------TLK-- 216 Query: 238 SLVTSSSGALKKQHKKPFDAMNNIVANLLLNLTSSARFEGSLNMDLNEISMNLVPFPQLH 297 L T + G L N++V+ + +T+ RF G LN DL ++++N+VPFP+LH Sbjct: 217 -LTTPTYGDL-----------NHLVSATMSGVTTCLRFPGQLNADLRKLAVNMVPFPRLH 264 Query: 298 YLVSSLTPLYTLTDVNIPPRRLDQMFSDAFSKDHQLLRADPKHSLYLACALMVRGNVQIS 357 + + PL + + ++ F + + DP+H YL A + RG + + Sbjct: 265 FFMPGFAPLTSRGSQQYRALTVPELTQQVFDAKNMMAACDPRHGRYLTVAAVFRGRMSMK 324 Query: 358 DLRRNIERL--KPSLQFVSWNQEGWKTSLCSVPPVGHSHSLLALANNTCVKPTFMELKER 415 ++ + + K S FV W KT++C +PP G ++ + N+T ++ F + E+ Sbjct: 325 EVDEQMLNVQNKNSSYFVEWIPNNVKTAVCDIPPRGLKMAVTFIGNSTAIQELFKRISEQ 384 Query: 416 FMRLYKKKAHLHHYLQVEGMEESCFTEAVSSLSALIQEYDQL-DAT 460 F ++++KA LH Y EGM+E FTEA S+++ L+ EY Q DAT Sbjct: 385 FTAMFRRKAFLHWYTG-EGMDEMEFTEAESNMNDLVSEYQQYQDAT 429 >gi|4507729 tubulin, beta 2 [Homo sapiens] Length = 445 Score = 260 bits (665), Expect = 2e-69 Identities = 151/464 (32%), Positives = 241/464 (51%), Gaps = 39/464 (8%) Query: 1 MTQSVVVQVGQCGNQIGCCFWDLALREHAAVNQKGIYDEAISSFFRNVDTRVVGDGGSIS 60 M + V +Q GQCGNQIG FW++ EH ++ G Y ++ G+ Sbjct: 1 MREIVHIQAGQCGNQIGAKFWEVISDEHG-IDPTGSYHGDSDLQLERINVYYNEAAGN-- 57 Query: 61 KGKICSLKARAVLIDMEEGVVNEILQGPLRDVFDTKQLITDISGSGNNWAVGHKVFGSLY 120 RA+L+D+E G ++ + GP +F + SG+GNNWA GH G+ Sbjct: 58 -----KYVPRAILVDLEPGTMDSVRSGPFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAEL 112 Query: 121 QDQILEKFRKSAEHCDCLQCFFIIHSMGGGTGSGLGTFLLKVLEDEFPEVYRFVTSIYPS 180 D +L+ RK +E CDCLQ F + HS+GGGTGSG+GT L+ + +E+P+ S+ PS Sbjct: 113 VDSVLDVVRKESESCDCLQGFQLTHSLGGGTGSGMGTLLISKIREEYPDRIMNTFSVMPS 172 Query: 181 GE-DDVITSPYNSILAMKELNEHADCVLPIDNQSLFDIISKIDLMVNSGKLGTTVKPKSL 239 + D + PYN+ L++ +L E+ D IDN++L+DI + T+K L Sbjct: 173 PKVSDTVVEPYNATLSVHQLVENTDETYSIDNEALYDICFR------------TLK---L 217 Query: 240 VTSSSGALKKQHKKPFDAMNNIVANLLLNLTSSARFEGSLNMDLNEISMNLVPFPQLHYL 299 T + G L N++V+ + +T+ RF G LN DL ++++N+VPFP+LH+ Sbjct: 218 TTPTYGDL-----------NHLVSATMSGVTTCLRFPGQLNADLRKLAVNMVPFPRLHFF 266 Query: 300 VSSLTPLYTLTDVNIPPRRLDQMFSDAFSKDHQLLRADPKHSLYLACALMVRGNVQISDL 359 + PL + + ++ F + + DP+H YL A + RG + + ++ Sbjct: 267 MPGFAPLTSRGSQQYRALTVPELTQQMFDSKNMMAACDPRHGRYLTVAAIFRGRMSMKEV 326 Query: 360 RRNIERL--KPSLQFVSWNQEGWKTSLCSVPPVGHSHSLLALANNTCVKPTFMELKERFM 417 + + K S FV W KT++C +PP G S + N+T ++ F + E+F Sbjct: 327 DEQMLNVQNKNSSYFVEWIPNNVKTAVCDIPPRGLKMSATFIGNSTAIQELFKRISEQFT 386 Query: 418 RLYKKKAHLHHYLQVEGMEESCFTEAVSSLSALIQEYDQL-DAT 460 ++++KA LH Y EGM+E FTEA S+++ L+ EY Q DAT Sbjct: 387 AMFRRKAFLHWYTG-EGMDEMEFTEAESNMNDLVSEYQQYQDAT 429 >gi|21361322 tubulin, beta 4 [Homo sapiens] Length = 444 Score = 260 bits (664), Expect = 2e-69 Identities = 156/466 (33%), Positives = 243/466 (52%), Gaps = 43/466 (9%) Query: 1 MTQSVVVQVGQCGNQIGCCFWDLALREHAAVNQKGIY--DEAISSFFRNVDTRVVGDGGS 58 M + V +Q GQCGNQIG FW++ EH ++ G Y D + NV G Sbjct: 1 MREIVHLQAGQCGNQIGAKFWEVISDEHG-IDPTGTYHGDSDLQLERINVYYNEATGGNY 59 Query: 59 ISKGKICSLKARAVLIDMEEGVVNEILQGPLRDVFDTKQLITDISGSGNNWAVGHKVFGS 118 + RAVL+D+E G ++ + GP +F + SG+GNNWA GH G+ Sbjct: 60 VP---------RAVLVDLEPGTMDSVRSGPFGQIFRPDNFVFGQSGAGNNWAKGHYTEGA 110 Query: 119 LYQDQILEKFRKSAEHCDCLQCFFIIHSMGGGTGSGLGTFLLKVLEDEFPEVYRFVTSIY 178 D +L+ RK AE CDCLQ F + HS+GGGTGSG+GT L+ + +EFP+ S+ Sbjct: 111 ELVDAVLDVVRKEAESCDCLQGFQLTHSLGGGTGSGMGTLLISKIREEFPDRIMNTFSVV 170 Query: 179 PSGE-DDVITSPYNSILAMKELNEHADCVLPIDNQSLFDIISKIDLMVNSGKLGTTVKPK 237 PS + D + PYN+ L++ +L E+ D IDN++L+DI + T+K Sbjct: 171 PSPKVSDTVVEPYNATLSVHQLVENTDETYCIDNEALYDICFR------------TLK-- 216 Query: 238 SLVTSSSGALKKQHKKPFDAMNNIVANLLLNLTSSARFEGSLNMDLNEISMNLVPFPQLH 297 L T + G L N++V+ + +T+ RF G LN DL ++++N+VPFP+LH Sbjct: 217 -LTTPTYGDL-----------NHLVSATMSGVTTCLRFPGQLNADLRKLAVNMVPFPRLH 264 Query: 298 YLVSSLTPLYTLTDVNIPPRRLDQMFSDAFSKDHQLLRADPKHSLYLACALMVRGNVQIS 357 + + PL + + ++ F + + DP+H YL A + RG + + Sbjct: 265 FFMPGFAPLTSRGSQQYRALTVPELTQQMFDAKNMMAACDPRHGRYLTVAAVFRGRMSMK 324 Query: 358 DLRRNI--ERLKPSLQFVSWNQEGWKTSLCSVPPVGHSHSLLALANNTCVKPTFMELKER 415 ++ + + K S FV W KT++C +PP G + + N+T ++ F + E+ Sbjct: 325 EVDEQMLSVQSKNSSYFVEWIPNNVKTAVCDIPPRGLKMAATFIGNSTAIQELFKRISEQ 384 Query: 416 FMRLYKKKAHLHHYLQVEGMEESCFTEAVSSLSALIQEYDQL-DAT 460 F ++++KA LH Y EGM+E FTEA S+++ L+ EY Q DAT Sbjct: 385 FTAMFRRKAFLHWYTG-EGMDEMEFTEAESNMNDLVSEYQQYQDAT 429 >gi|5174735 tubulin, beta, 2 [Homo sapiens] Length = 445 Score = 260 bits (664), Expect = 2e-69 Identities = 154/464 (33%), Positives = 242/464 (52%), Gaps = 39/464 (8%) Query: 1 MTQSVVVQVGQCGNQIGCCFWDLALREHAAVNQKGIYDEAISSFFRNVDTRVVGDGGSIS 60 M + V +Q GQCGNQIG FW++ EH ++ G Y ++ + Sbjct: 1 MREIVHLQAGQCGNQIGAKFWEVISDEHG-IDPTGTYHGDSDLQLERINVYY----NEAT 55 Query: 61 KGKICSLKARAVLIDMEEGVVNEILQGPLRDVFDTKQLITDISGSGNNWAVGHKVFGSLY 120 GK RAVL+D+E G ++ + GP +F + SG+GNNWA GH G+ Sbjct: 56 GGKYVP---RAVLVDLEPGTMDSVRSGPFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAEL 112 Query: 121 QDQILEKFRKSAEHCDCLQCFFIIHSMGGGTGSGLGTFLLKVLEDEFPEVYRFVTSIYPS 180 D +L+ RK AE CDCLQ F + HS+GGGTGSG+GT L+ + +E+P+ S+ PS Sbjct: 113 VDSVLDVVRKEAESCDCLQGFQLTHSLGGGTGSGMGTLLISKIREEYPDRIMNTFSVVPS 172 Query: 181 GE-DDVITSPYNSILAMKELNEHADCVLPIDNQSLFDIISKIDLMVNSGKLGTTVKPKSL 239 + D + PYN+ L++ +L E+ D IDN++L+DI + T+K L Sbjct: 173 PKVSDTVVEPYNATLSVHQLVENTDETYCIDNEALYDICFR------------TLK---L 217 Query: 240 VTSSSGALKKQHKKPFDAMNNIVANLLLNLTSSARFEGSLNMDLNEISMNLVPFPQLHYL 299 T + G L N++V+ + +T+ RF G LN DL ++++N+VPFP+LH+ Sbjct: 218 TTPTYGDL-----------NHLVSATMSGVTTCLRFPGQLNADLRKLAVNMVPFPRLHFF 266 Query: 300 VSSLTPLYTLTDVNIPPRRLDQMFSDAFSKDHQLLRADPKHSLYLACALMVRGNVQISDL 359 + PL + + ++ F + + DP+H YL A + RG + + ++ Sbjct: 267 MPGFAPLTSRGSQQYRALTVPELTQQMFDAKNMMAACDPRHGRYLTVAAVFRGRMSMKEV 326 Query: 360 RRNIERL--KPSLQFVSWNQEGWKTSLCSVPPVGHSHSLLALANNTCVKPTFMELKERFM 417 + + K S FV W KT++C +PP G S + N+T ++ F + E+F Sbjct: 327 DEQMLNVQNKNSSYFVEWIPNNVKTAVCDIPPRGLKMSATFIGNSTAIQELFKRISEQFT 386 Query: 418 RLYKKKAHLHHYLQVEGMEESCFTEAVSSLSALIQEYDQL-DAT 460 ++++KA LH Y EGM+E FTEA S+++ L+ EY Q DAT Sbjct: 387 AMFRRKAFLHWYTG-EGMDEMEFTEAESNMNDLVSEYQQYQDAT 429 >gi|29788768 tubulin, beta 2B [Homo sapiens] Length = 445 Score = 259 bits (662), Expect = 4e-69 Identities = 150/464 (32%), Positives = 242/464 (52%), Gaps = 39/464 (8%) Query: 1 MTQSVVVQVGQCGNQIGCCFWDLALREHAAVNQKGIYDEAISSFFRNVDTRVVGDGGSIS 60 M + V +Q GQCGNQIG FW++ EH + S+ + D ++ + Sbjct: 1 MREIVHIQAGQCGNQIGAKFWEVISDEHGI--------DPTGSYHGDSDLQLERINVYYN 52 Query: 61 KGKICSLKARAVLIDMEEGVVNEILQGPLRDVFDTKQLITDISGSGNNWAVGHKVFGSLY 120 + RA+L+D+E G ++ + GP +F + SG+GNNWA GH G+ Sbjct: 53 EATGNKYVPRAILVDLEPGTMDSVRSGPFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAEL 112 Query: 121 QDQILEKFRKSAEHCDCLQCFFIIHSMGGGTGSGLGTFLLKVLEDEFPEVYRFVTSIYPS 180 D +L+ RK +E CDCLQ F + HS+GGGTGSG+GT L+ + +E+P+ S+ PS Sbjct: 113 VDSVLDVVRKESESCDCLQGFQLTHSLGGGTGSGMGTLLISKIREEYPDRIMNTFSVMPS 172 Query: 181 GE-DDVITSPYNSILAMKELNEHADCVLPIDNQSLFDIISKIDLMVNSGKLGTTVKPKSL 239 + D + PYN+ L++ +L E+ D IDN++L+DI + T+K L Sbjct: 173 PKVSDTVVEPYNATLSVHQLVENTDETYCIDNEALYDICFR------------TLK---L 217 Query: 240 VTSSSGALKKQHKKPFDAMNNIVANLLLNLTSSARFEGSLNMDLNEISMNLVPFPQLHYL 299 T + G L N++V+ + +T+ RF G LN DL ++++N+VPFP+LH+ Sbjct: 218 TTPTYGDL-----------NHLVSATMSGVTTCLRFPGQLNADLRKLAVNMVPFPRLHFF 266 Query: 300 VSSLTPLYTLTDVNIPPRRLDQMFSDAFSKDHQLLRADPKHSLYLACALMVRGNVQISDL 359 + PL + + ++ F + + DP+H YL A + RG + + ++ Sbjct: 267 MPGFAPLTSRGSQQYRALTVPELTQQMFDSKNMMAACDPRHGRYLTVAAIFRGRMSMKEV 326 Query: 360 RRNIERL--KPSLQFVSWNQEGWKTSLCSVPPVGHSHSLLALANNTCVKPTFMELKERFM 417 + + K S FV W KT++C +PP G S + N+T ++ F + E+F Sbjct: 327 DEQMLNVQNKNSSYFVEWIPNNVKTAVCDIPPRGLKMSATFIGNSTAIQELFKRISEQFT 386 Query: 418 RLYKKKAHLHHYLQVEGMEESCFTEAVSSLSALIQEYDQL-DAT 460 ++++KA LH Y EGM+E FTEA S+++ L+ EY Q DAT Sbjct: 387 AMFRRKAFLHWYTG-EGMDEMEFTEAESNMNDLVSEYQQYQDAT 429 >gi|14210536 tubulin, beta 6 [Homo sapiens] Length = 446 Score = 257 bits (657), Expect = 1e-68 Identities = 154/466 (33%), Positives = 241/466 (51%), Gaps = 39/466 (8%) Query: 1 MTQSVVVQVGQCGNQIGCCFWDLALREHAAVNQKGIYDEAISSFFRNVDTRVVGDGGSIS 60 M + V +Q GQCGNQIG FW++ EH G ++ R V + S Sbjct: 1 MREIVHIQAGQCGNQIGTKFWEVISDEHGIDPAGGYVGDSALQLER---INVYYNESSSQ 57 Query: 61 KGKICSLKARAVLIDMEEGVVNEILQGPLRDVFDTKQLITDISGSGNNWAVGHKVFGSLY 120 K RA L+D+E G ++ + GP +F I +G+GNNWA GH G+ Sbjct: 58 K-----YVPRAALVDLEPGTMDSVRSGPFGQLFRPDNFIFGQTGAGNNWAKGHYTEGAEL 112 Query: 121 QDQILEKFRKSAEHCDCLQCFFIIHSMGGGTGSGLGTFLLKVLEDEFPEVYRFVTSIYPS 180 D +L+ RK EHCDCLQ F + HS+GGGTGSG+GT L+ + +EFP+ S+ PS Sbjct: 113 VDAVLDVVRKECEHCDCLQGFQLTHSLGGGTGSGMGTLLISKIREEFPDRIMNTFSVMPS 172 Query: 181 GE-DDVITSPYNSILAMKELNEHADCVLPIDNQSLFDIISKIDLMVNSGKLGTTVKPKSL 239 + D + PYN+ L++ +L E+ D IDN++L+DI + T+K L Sbjct: 173 PKVSDTVVEPYNATLSVHQLVENTDETYCIDNEALYDICFR------------TLK---L 217 Query: 240 VTSSSGALKKQHKKPFDAMNNIVANLLLNLTSSARFEGSLNMDLNEISMNLVPFPQLHYL 299 T + G L N++V+ + +T+S RF G LN DL ++++N+VPFP+LH+ Sbjct: 218 TTPTYGDL-----------NHLVSATMSGVTTSLRFPGQLNADLRKLAVNMVPFPRLHFF 266 Query: 300 VSSLTPLYTLTDVNIPPRRLDQMFSDAFSKDHQLLRADPKHSLYLACALMVRGNVQISDL 359 + PL + + ++ F + + DP+H YL A + RG + + ++ Sbjct: 267 MPGFAPLTSRGSQQYRALTVPELTQQMFDARNMMAACDPRHGRYLTVATVFRGPMSMKEV 326 Query: 360 RRNIERL--KPSLQFVSWNQEGWKTSLCSVPPVGHSHSLLALANNTCVKPTFMELKERFM 417 + + K S FV W K ++C +PP G + + N+T ++ F + E+F Sbjct: 327 DEQMLAIQSKNSSYFVEWIPNNVKVAVCDIPPRGLKMASTFIGNSTAIQELFKRISEQFS 386 Query: 418 RLYKKKAHLHHYLQVEGMEESCFTEAVSSLSALIQEYDQL-DATKN 462 ++++KA L H+ EGM+E FTEA S+++ L+ EY Q DAT N Sbjct: 387 AMFRRKAFL-HWFTGEGMDEMEFTEAESNMNDLVSEYQQYQDATAN 431 >gi|50592996 tubulin, beta, 4 [Homo sapiens] Length = 450 Score = 255 bits (652), Expect = 5e-68 Identities = 152/470 (32%), Positives = 239/470 (50%), Gaps = 51/470 (10%) Query: 1 MTQSVVVQVGQCGNQIGCCFWDLALREHAA------VNQKGIYDEAISSFFRNVDTRVVG 54 M + V +Q GQCGNQIG FW++ EH V + E IS ++ + Sbjct: 1 MREIVHIQAGQCGNQIGAKFWEVISDEHGIDPSGNYVGDSDLQLERISVYYNEASSH--- 57 Query: 55 DGGSISKGKICSLKARAVLIDMEEGVVNEILQGPLRDVFDTKQLITDISGSGNNWAVGHK 114 RA+L+D+E G ++ + G +F I SG+GNNWA GH Sbjct: 58 -----------KYVPRAILVDLEPGTMDSVRSGAFGHLFRPDNFIFGQSGAGNNWAKGHY 106 Query: 115 VFGSLYQDQILEKFRKSAEHCDCLQCFFIIHSMGGGTGSGLGTFLLKVLEDEFPEVYRFV 174 G+ D +L+ RK E+CDCLQ F + HS+GGGTGSG+GT L+ + +E+P+ Sbjct: 107 TEGAELVDSVLDVVRKECENCDCLQGFQLTHSLGGGTGSGMGTLLISKVREEYPDRIMNT 166 Query: 175 TSIYPSGE-DDVITSPYNSILAMKELNEHADCVLPIDNQSLFDIISKIDLMVNSGKLGTT 233 S+ PS + D + PYN+ L++ +L E+ D IDN++L+DI + T Sbjct: 167 FSVVPSPKVSDTVVEPYNATLSIHQLVENTDETYCIDNEALYDICFR------------T 214 Query: 234 VKPKSLVTSSSGALKKQHKKPFDAMNNIVANLLLNLTSSARFEGSLNMDLNEISMNLVPF 293 +K L T + G L N++V+ + +T+S RF G LN DL ++++N+VPF Sbjct: 215 LK---LATPTYGDL-----------NHLVSATMSGVTTSLRFPGQLNADLRKLAVNMVPF 260 Query: 294 PQLHYLVSSLTPLYTLTDVNIPPRRLDQMFSDAFSKDHQLLRADPKHSLYLACALMVRGN 353 P+LH+ + PL + ++ F + + DP+H YL A + RG Sbjct: 261 PRLHFFMPGFAPLTARGSQQYRALTVPELTQQMFDAKNMMAACDPRHGRYLTVATVFRGR 320 Query: 354 VQISDLRRNIERL--KPSLQFVSWNQEGWKTSLCSVPPVGHSHSLLALANNTCVKPTFME 411 + + ++ + + K S FV W K ++C +PP G S + N+T ++ F Sbjct: 321 MSMKEVDEQMLAIQSKNSSYFVEWIPNNVKVAVCDIPPRGLKMSSTFIGNSTAIQELFKR 380 Query: 412 LKERFMRLYKKKAHLHHYLQVEGMEESCFTEAVSSLSALIQEYDQL-DAT 460 + E+F ++++KA LH Y EGM+E FTEA S+++ L+ EY Q DAT Sbjct: 381 ISEQFTAMFRRKAFLHWYTG-EGMDEMEFTEAESNMNDLVSEYQQYQDAT 429 >gi|13562114 beta tubulin 1, class VI [Homo sapiens] Length = 451 Score = 245 bits (625), Expect = 7e-65 Identities = 150/476 (31%), Positives = 242/476 (50%), Gaps = 50/476 (10%) Query: 1 MTQSVVVQVGQCGNQIGCCFWDLALREHA---AVNQKG---IYDEAISSFFRNVDTRVVG 54 M + V +Q+GQCGNQIG FW++ EH A + +G + E IS ++ R Sbjct: 1 MREIVHIQIGQCGNQIGAKFWEMIGEEHGIDLAGSDRGASALQLERISVYYNEAYGR--- 57 Query: 55 DGGSISKGKICSLKARAVLIDMEEGVVNEILQGPLRDVFDTKQLITDISGSGNNWAVGHK 114 RAVL+D+E G ++ I L +F + SG+GNNWA GH Sbjct: 58 -----------KYVPRAVLVDLEPGTMDSIRSSKLGALFQPDSFVHGNSGAGNNWAKGHY 106 Query: 115 VFGSLYQDQILEKFRKSAEHCDCLQCFFIIHSMGGGTGSGLGTFLLKVLEDEFPEVYRFV 174 G+ + +LE R +E CDCLQ F I+HS+GGGTGSG+GT L+ + +E+P+ Sbjct: 107 TEGAELIENVLEVVRHESESCDCLQGFQIVHSLGGGTGSGMGTLLMNKIREEYPDRIMNS 166 Query: 175 TSIYPSGE-DDVITSPYNSILAMKELNEHADCVLPIDNQSLFDIISKIDLMVNSGKLGTT 233 S+ PS + D + PYN++L++ +L E+AD IDN++L+DI + T Sbjct: 167 FSVMPSPKVSDTVVEPYNAVLSIHQLIENADACFCIDNEALYDICFR------------T 214 Query: 234 VKPKSLVTSSSGALKKQHKKPFDAMNNIVANLLLNLTSSARFEGSLNMDLNEISMNLVPF 293 +K L T + G L N++V+ + +T+S RF G LN DL ++++N+VPF Sbjct: 215 LK---LTTPTYGDL-----------NHLVSLTMSGITTSLRFPGQLNADLRKLAVNMVPF 260 Query: 294 PQLHYLVSSLTPLYTLTDVNIPPRRLDQMFSDAFSKDHQLLRADPKHSLYLACALMVRGN 353 P+LH+ + PL + ++ F + + D + YL A + RG Sbjct: 261 PRLHFFMPGFAPLTAQGSQQYRALSVAELTQQMFDARNTMAACDLRRGRYLTVACIFRGK 320 Query: 354 VQISDLRRNI--ERLKPSLQFVSWNQEGWKTSLCSVPPVGHSHSLLALANNTCVKPTFME 411 + ++ + + + + S FV W K ++C +PP G S + + NNT ++ F Sbjct: 321 MSTKEVDQQLLSVQTRNSSCFVEWIPNNVKVAVCDIPPRGLSMAATFIGNNTAIQEIFNR 380 Query: 412 LKERFMRLYKKKAHLHHYLQVEGMEESCFTEAVSSLSALIQEYDQLDATKNMPVQD 467 + E F ++K+KA +H Y EGM+ + F EA +++ L+ EY Q K + +D Sbjct: 381 VSEHFSAMFKRKAFVHWYTS-EGMDINEFGEAENNIHDLVSEYQQFQDAKAVLEED 435 >gi|55770868 tubulin, beta polypeptide 4, member Q [Homo sapiens] Length = 434 Score = 244 bits (623), Expect = 1e-64 Identities = 153/466 (32%), Positives = 240/466 (51%), Gaps = 44/466 (9%) Query: 1 MTQSVVVQVGQCGNQIGCCFWDLALREHAAVNQKGIY--DEAISSFFRNVDTRVVGDGGS 58 M + V+ Q GQCGNQIG FW++ EHA ++ G Y D + NV G Sbjct: 1 MRELVLTQTGQCGNQIGAKFWEVISDEHA-IDSAGTYHGDSHLQLERINVHHHEASGGRY 59 Query: 59 ISKGKICSLKARAVLIDMEEGVVNEILQGPLRDVFDTKQLITDISGSGNNWAVGHKVFGS 118 +S RAVL+D+E G ++ + GP VF I+ G+GNNWA G G+ Sbjct: 60 VS---------RAVLVDLEPGTMDSVRSGPFGQVFRPDNFISRQCGAGNNWAKGRYTEGA 110 Query: 119 LYQDQILEKFRKSAEHCDCLQCFFIIHSMGGGTGSGLGTFLLKVLEDEFPE-VYRFVTSI 177 + +++ RK AE CDCLQ F + HS+GGGTGSG+GT L+ + +E+P+ + ++ + Sbjct: 111 ELTESVMDVVRKEAESCDCLQGFQLTHSLGGGTGSGMGTLLISKIWEEYPDRIINTLSIL 170 Query: 178 YPSGEDDVITSPYNSILAMKELNEHADCVLPIDNQSLFDIISKIDLMVNSGKLGTTVKPK 237 D + PYN+ L++ +L E+AD IDN++L+DI S+ T+K Sbjct: 171 LLPKVSDTVVEPYNATLSVHQLIENADETFCIDNEALYDICSR------------TLK-- 216 Query: 238 SLVTSSSGALKKQHKKPFDAMNNIVANLLLNLTSSARFEGSLNMDLNEISMNLVPFPQLH 297 L T + G L N++V+ + +T+ F LN DL +++MN+VPFP+LH Sbjct: 217 -LPTPTYGDL-----------NHLVSATMSGVTTCLCFPDQLNADLRKLAMNMVPFPRLH 264 Query: 298 YLVSSLTPLYTLTDVNIPPRRLDQMFSDAFSKDHQLLRADPKHSLYLACALMVRGNVQIS 357 + + PL + + ++ F + + DP+H YL A + +G + + Sbjct: 265 FFMPGFAPLTSRGSQQYRALTVAELTQQMFDAKNMMAARDPRHGRYLTAAAIFQGRMPMR 324 Query: 358 DLRRNIERL--KPSLQFVSWNQEGWKTSLCSVPPVGHSHSLLALANNTCVKPTFMELKER 415 ++ + + K S F W KT++C +PP G S+ NNT V+ + E+ Sbjct: 325 EVDEQMFNIQDKNSSYFADWFPNNVKTAVCDIPPWGLKMSVTFTGNNTAVQ-ELKRVSEQ 383 Query: 416 FMRLYKKKAHLHHYLQVEGMEESCFTEAVSSLSALIQEYDQL-DAT 460 F +++KA LH Y EGM+E FTEA S+++ L+ EY Q DAT Sbjct: 384 FTATFRRKAFLHWYTG-EGMDEMEFTEAESNMNDLVSEYQQYQDAT 428 >gi|17921989 tubulin, alpha 4a [Homo sapiens] Length = 448 Score = 235 bits (600), Expect = 6e-62 Identities = 141/474 (29%), Positives = 240/474 (50%), Gaps = 56/474 (11%) Query: 1 MTQSVVVQVGQCGNQIGCCFWDLALREHAAVNQKGIYDEAISSFFRNVDTRVVGDGGSIS 60 M + + V VGQ G Q+G W+L EH GI + + + +G G Sbjct: 1 MRECISVHVGQAGVQMGNACWELYCLEH------GIQPDG-----QMPSDKTIGGGDDSF 49 Query: 61 KGKICSLKA-----RAVLIDMEEGVVNEILQGPLRDVFDTKQLITDISGSGNNWAVGHKV 115 C A RAV +D+E V++EI GP R +F +QLIT + NN+A GH Sbjct: 50 TTFFCETGAGKHVPRAVFVDLEPTVIDEIRNGPYRQLFHPEQLITGKEDAANNYARGHYT 109 Query: 116 FGSLYQDQILEKFRKSAEHCDCLQCFFIIHSMGGGTGSGLGTFLLKVLEDEFPEVYRFVT 175 G D +L++ RK ++ C LQ F + HS GGGTGSG + L++ L ++ + + Sbjct: 110 IGKEIIDPVLDRIRKLSDQCTGLQGFLVFHSFGGGTGSGFTSLLMERLSVDYGKKSKLEF 169 Query: 176 SIYPSGE-DDVITSPYNSILAMKELNEHADCVLPIDNQSLFDIISK-IDLMVNSGKLGTT 233 SIYP+ + + PYNSIL EH+DC +DN++++DI + +D+ Sbjct: 170 SIYPAPQVSTAVVEPYNSILTTHTTLEHSDCAFMVDNEAIYDICRRNLDI---------- 219 Query: 234 VKPKSLVTSSSGALKKQHKKPFDAMNNIVANLLLNLTSSARFEGSLNMDLNEISMNLVPF 293 + + +N +++ ++ ++T+S RF+G+LN+DL E NLVP+ Sbjct: 220 -----------------ERPTYTNLNRLISQIVSSITASLRFDGALNVDLTEFQTNLVPY 262 Query: 294 PQLHYLVSSLTPLYTLTDVNIPPRRLDQMFSDAFSKDHQLLRADPKHSLYLACALMVRGN 353 P++H+ +++ P+ + + ++ + F +Q+++ DP+H Y+AC L+ RG+ Sbjct: 263 PRIHFPLATYAPVISAEKAYHEQLSVAEITNACFEPANQMVKCDPRHGKYMACCLLYRGD 322 Query: 354 VQISDLRRNIERLKP--SLQFVSWNQEGWKTSLCSVPP--------VGHSHSLLALANNT 403 V D+ I +K S+QFV W G+K + PP ++ L+N T Sbjct: 323 VVPKDVNAAIAAIKTKRSIQFVDWCPTGFKVGINYQPPTVVPGGDLAKVQRAVCMLSNTT 382 Query: 404 CVKPTFMELKERFMRLYKKKAHLHHYLQVEGMEESCFTEAVSSLSALIQEYDQL 457 + + L +F +Y K+A +H Y+ EGMEE F+EA ++AL ++Y+++ Sbjct: 383 AIAEAWARLDHKFDLMYAKRAFVHWYVG-EGMEEGEFSEAREDMAALEKDYEEV 435 >gi|9507215 tubulin, alpha 8 [Homo sapiens] Length = 449 Score = 234 bits (596), Expect = 2e-61 Identities = 143/469 (30%), Positives = 237/469 (50%), Gaps = 46/469 (9%) Query: 1 MTQSVVVQVGQCGNQIGCCFWDLALREHAAVNQKGIYDEAISSFFRNVDTRVVGDGGSIS 60 M + + V VGQ G QIG W+L EH + G +D S N D Sbjct: 1 MRECISVHVGQAGVQIGNACWELFCLEHG-IQADGTFDAQASKI--NDDDSFTTFFSETG 57 Query: 61 KGKICSLKARAVLIDMEEGVVNEILQGPLRDVFDTKQLITDISGSGNNWAVGHKVFGSLY 120 GK RAV+ID+E VV+E+ G R +F +QLIT + NN+A GH G Sbjct: 58 NGKHVP---RAVMIDLEPTVVDEVRAGTYRQLFHPEQLITGKEDAANNYARGHYTVGKES 114 Query: 121 QDQILEKFRKSAEHCDCLQCFFIIHSMGGGTGSGLGTFLLKVLEDEFPEVYRFVTSIYPS 180 D +L++ RK + C LQ F I HS GGGTGSG + L++ L ++ + + +IYP+ Sbjct: 115 IDLVLDRIRKLTDACSGLQGFLIFHSFGGGTGSGFTSLLMERLSLDYGKKSKLEFAIYPA 174 Query: 181 GE-DDVITSPYNSILAMKELNEHADCVLPIDNQSLFDIISK-IDLMVNSGKLGTTVKPKS 238 + + PYNSIL EH+DC +DN++++DI + +D+ Sbjct: 175 PQVSTAVVEPYNSILTTHTTLEHSDCAFMVDNEAIYDICRRNLDI--------------- 219 Query: 239 LVTSSSGALKKQHKKPFDAMNNIVANLLLNLTSSARFEGSLNMDLNEISMNLVPFPQLHY 298 + + +N +++ ++ ++T+S RF+G+LN+DL E NLVP+P++H+ Sbjct: 220 ------------ERPTYTNLNRLISQIVSSITASLRFDGALNVDLTEFQTNLVPYPRIHF 267 Query: 299 LVSSLTPLYTLTDVNIPPRRLDQMFSDAFSKDHQLLRADPKHSLYLACALMVRGNVQISD 358 + + P+ + + ++ S F + Q+++ DP+H Y+AC ++ RG+V D Sbjct: 268 PLVTYAPIISAEKAYHEQLSVAEITSSCFEPNSQMVKCDPRHGKYMACCMLYRGDVVPKD 327 Query: 359 LRRNIERLKP--SLQFVSWNQEGWKTSLCSVPP--------VGHSHSLLALANNTCVKPT 408 + I +K ++QFV W G+K + PP ++ L+N T + Sbjct: 328 VNVAIAAIKTKRTIQFVDWCPTGFKVGINYQPPTVVPGGDLAKVQRAVCMLSNTTAIAEA 387 Query: 409 FMELKERFMRLYKKKAHLHHYLQVEGMEESCFTEAVSSLSALIQEYDQL 457 + L +F +Y K+A +H Y+ EGMEE F+EA L+AL ++Y+++ Sbjct: 388 WARLDHKFDLMYAKRAFVHWYVG-EGMEEGEFSEAREDLAALEKDYEEV 435 >gi|14389309 tubulin alpha 6 [Homo sapiens] Length = 449 Score = 232 bits (592), Expect = 5e-61 Identities = 141/479 (29%), Positives = 242/479 (50%), Gaps = 62/479 (12%) Query: 1 MTQSVVVQVGQCGNQIGCCFWDLALREHA--------AVNQKGIYDEAISSFFRNVDTRV 52 M + + + VGQ G QIG W+L EH + G D++ ++FF Sbjct: 1 MRECISIHVGQAGVQIGNACWELYCLEHGIQPDGQMPSDKTIGGGDDSFNTFFSET---- 56 Query: 53 VGDGGSISKGKICSLKARAVLIDMEEGVVNEILQGPLRDVFDTKQLITDISGSGNNWAVG 112 G G + RAV +D+E V++E+ G R +F +QLIT + NN+A G Sbjct: 57 -GAGKHVP---------RAVFVDLEPTVIDEVRTGTYRQLFHPEQLITGKEDAANNYARG 106 Query: 113 HKVFGSLYQDQILEKFRKSAEHCDCLQCFFIIHSMGGGTGSGLGTFLLKVLEDEFPEVYR 172 H G D +L++ RK A+ C LQ F + HS GGGTGSG + L++ L ++ + + Sbjct: 107 HYTIGKEIIDLVLDRIRKLADQCTGLQGFLVFHSFGGGTGSGFTSLLMERLSVDYGKKSK 166 Query: 173 FVTSIYPSGE-DDVITSPYNSILAMKELNEHADCVLPIDNQSLFDIISK-IDLMVNSGKL 230 SIYP+ + + PYNSIL EH+DC +DN++++DI + +D+ Sbjct: 167 LEFSIYPAPQVSTAVVEPYNSILTTHTTLEHSDCAFMVDNEAIYDICRRNLDI------- 219 Query: 231 GTTVKPKSLVTSSSGALKKQHKKPFDAMNNIVANLLLNLTSSARFEGSLNMDLNEISMNL 290 + + +N +++ ++ ++T+S RF+G+LN+DL E NL Sbjct: 220 --------------------ERPTYTNLNRLISQIVSSITASLRFDGALNVDLTEFQTNL 259 Query: 291 VPFPQLHYLVSSLTPLYTLTDVNIPPRRLDQMFSDAFSKDHQLLRADPKHSLYLACALMV 350 VP+P++H+ +++ P+ + + ++ + F +Q+++ DP+H Y+AC L+ Sbjct: 260 VPYPRIHFPLATYAPVISAEKAYHEQLTVAEITNACFEPANQMVKCDPRHGKYMACCLLY 319 Query: 351 RGNVQISDLRRNIERLKP--SLQFVSWNQEGWKTSLCSVPP--------VGHSHSLLALA 400 RG+V D+ I +K ++QFV W G+K + PP ++ L+ Sbjct: 320 RGDVVPKDVNAAIATIKTKRTIQFVDWCPTGFKVGINYQPPTVVPGGDLAKVQRAVCMLS 379 Query: 401 NNTCVKPTFMELKERFMRLYKKKAHLHHYLQVEGMEESCFTEAVSSLSALIQEYDQLDA 459 N T V + L +F +Y K+A +H Y+ EGMEE F+EA ++AL ++Y+++ A Sbjct: 380 NTTAVAEAWARLDHKFDLMYAKRAFVHWYVG-EGMEEGEFSEAREDMAALEKDYEEVGA 437 >gi|57013276 tubulin, alpha, ubiquitous [Homo sapiens] Length = 451 Score = 232 bits (591), Expect = 6e-61 Identities = 140/477 (29%), Positives = 241/477 (50%), Gaps = 62/477 (12%) Query: 1 MTQSVVVQVGQCGNQIGCCFWDLALREHA--------AVNQKGIYDEAISSFFRNVDTRV 52 M + + + VGQ G QIG W+L EH + G D++ ++FF Sbjct: 1 MRECISIHVGQAGVQIGNACWELYCLEHGIQPDGQMPSDKTIGGGDDSFNTFFSET---- 56 Query: 53 VGDGGSISKGKICSLKARAVLIDMEEGVVNEILQGPLRDVFDTKQLITDISGSGNNWAVG 112 G G + RAV +D+E V++E+ G R +F +QLIT + NN+A G Sbjct: 57 -GAGKHVP---------RAVFVDLEPTVIDEVRTGTYRQLFHPEQLITGKEDAANNYARG 106 Query: 113 HKVFGSLYQDQILEKFRKSAEHCDCLQCFFIIHSMGGGTGSGLGTFLLKVLEDEFPEVYR 172 H G D +L++ RK A+ C LQ F + HS GGGTGSG + L++ L ++ + + Sbjct: 107 HYTIGKEIIDLVLDRIRKLADQCTGLQGFLVFHSFGGGTGSGFTSLLMERLSVDYGKKSK 166 Query: 173 FVTSIYPSGE-DDVITSPYNSILAMKELNEHADCVLPIDNQSLFDIISK-IDLMVNSGKL 230 SIYP+ + + PYNSIL EH+DC +DN++++DI + +D+ Sbjct: 167 LEFSIYPAPQVSTAVVEPYNSILTTHTTLEHSDCAFMVDNEAIYDICRRNLDI------- 219 Query: 231 GTTVKPKSLVTSSSGALKKQHKKPFDAMNNIVANLLLNLTSSARFEGSLNMDLNEISMNL 290 + + +N +++ ++ ++T+S RF+G+LN+DL E NL Sbjct: 220 --------------------ERPTYTNLNRLISQIVSSITASLRFDGALNVDLTEFQTNL 259 Query: 291 VPFPQLHYLVSSLTPLYTLTDVNIPPRRLDQMFSDAFSKDHQLLRADPKHSLYLACALMV 350 VP+P++H+ +++ P+ + + ++ + F +Q+++ DP+H Y+AC L+ Sbjct: 260 VPYPRIHFPLATYAPVISAEKAYHEQLSVAEITNACFEPANQMVKCDPRHGKYMACCLLY 319 Query: 351 RGNVQISDLRRNIERLKP--SLQFVSWNQEGWKTSLCSVPP--------VGHSHSLLALA 400 RG+V D+ I +K S+QFV W G+K + PP ++ L+ Sbjct: 320 RGDVVPKDVNAAIATIKTKRSIQFVDWCPTGFKVGINYQPPTVVPGGDLAKVQRAVCMLS 379 Query: 401 NNTCVKPTFMELKERFMRLYKKKAHLHHYLQVEGMEESCFTEAVSSLSALIQEYDQL 457 N T + + L +F +Y K+A +H Y+ EGMEE F+EA ++AL ++Y+++ Sbjct: 380 NTTAIAEAWARLDHKFDLMYAKRAFVHWYVG-EGMEEGEFSEAREDMAALEKDYEEV 435 >gi|17986283 tubulin, alpha 1a [Homo sapiens] Length = 451 Score = 230 bits (587), Expect = 2e-60 Identities = 139/477 (29%), Positives = 240/477 (50%), Gaps = 62/477 (12%) Query: 1 MTQSVVVQVGQCGNQIGCCFWDLALREHA--------AVNQKGIYDEAISSFFRNVDTRV 52 M + + + VGQ G QIG W+L EH + G D++ ++FF Sbjct: 1 MRECISIHVGQAGVQIGNACWELYCLEHGIQPDGQMPSDKTIGGGDDSFNTFFSET---- 56 Query: 53 VGDGGSISKGKICSLKARAVLIDMEEGVVNEILQGPLRDVFDTKQLITDISGSGNNWAVG 112 G G + RAV +D+E V++E+ G R +F +QLIT + NN+A G Sbjct: 57 -GAGKHVP---------RAVFVDLEPTVIDEVRTGTYRQLFHPEQLITGKEDAANNYARG 106 Query: 113 HKVFGSLYQDQILEKFRKSAEHCDCLQCFFIIHSMGGGTGSGLGTFLLKVLEDEFPEVYR 172 H G D +L++ RK A+ C LQ F + HS GGGTGSG + L++ L ++ + + Sbjct: 107 HYTIGKEIIDLVLDRIRKLADQCTGLQGFLVFHSFGGGTGSGFTSLLMERLSVDYGKKSK 166 Query: 173 FVTSIYPSGE-DDVITSPYNSILAMKELNEHADCVLPIDNQSLFDIISK-IDLMVNSGKL 230 SIYP+ + + PYNSIL EH+DC +DN++++DI + +D+ Sbjct: 167 LEFSIYPAPQVSTAVVEPYNSILTTHTTLEHSDCAFMVDNEAIYDICRRNLDI------- 219 Query: 231 GTTVKPKSLVTSSSGALKKQHKKPFDAMNNIVANLLLNLTSSARFEGSLNMDLNEISMNL 290 + + +N ++ ++ ++T+S RF+G+LN+DL E NL Sbjct: 220 --------------------ERPTYTNLNRLIGQIVSSITASLRFDGALNVDLTEFQTNL 259 Query: 291 VPFPQLHYLVSSLTPLYTLTDVNIPPRRLDQMFSDAFSKDHQLLRADPKHSLYLACALMV 350 VP+P++H+ +++ P+ + + ++ + F +Q+++ DP+H Y+AC L+ Sbjct: 260 VPYPRIHFPLATYAPVISAEKAYHEQLSVAEITNACFEPANQMVKCDPRHGKYMACCLLY 319 Query: 351 RGNVQISDLRRNIERLKP--SLQFVSWNQEGWKTSLCSVPP--------VGHSHSLLALA 400 RG+V D+ I +K ++QFV W G+K + PP ++ L+ Sbjct: 320 RGDVVPKDVNAAIATIKTKRTIQFVDWCPTGFKVGINYQPPTVVPGGDLAKVQRAVCMLS 379 Query: 401 NNTCVKPTFMELKERFMRLYKKKAHLHHYLQVEGMEESCFTEAVSSLSALIQEYDQL 457 N T + + L +F +Y K+A +H Y+ EGMEE F+EA ++AL ++Y+++ Sbjct: 380 NTTAIAEAWARLDHKFDLMYAKRAFVHWYVG-EGMEEGEFSEAREDMAALEKDYEEV 435 >gi|156564363 tubulin, alpha 3d [Homo sapiens] Length = 450 Score = 230 bits (586), Expect = 2e-60 Identities = 140/477 (29%), Positives = 240/477 (50%), Gaps = 62/477 (12%) Query: 1 MTQSVVVQVGQCGNQIGCCFWDLALREHA--------AVNQKGIYDEAISSFFRNVDTRV 52 M + + + VGQ G QIG W+L EH + G D++ ++FF Sbjct: 1 MRECISIHVGQAGVQIGNACWELYCLEHGIQPDGQMPSDKTIGGGDDSFNTFFSET---- 56 Query: 53 VGDGGSISKGKICSLKARAVLIDMEEGVVNEILQGPLRDVFDTKQLITDISGSGNNWAVG 112 G G + RAV +D+E VV+E+ G R +F +QLIT + NN+A G Sbjct: 57 -GAGKHVP---------RAVFVDLEPTVVDEVRTGTYRQLFHPEQLITGKEDAANNYARG 106 Query: 113 HKVFGSLYQDQILEKFRKSAEHCDCLQCFFIIHSMGGGTGSGLGTFLLKVLEDEFPEVYR 172 H G D +L++ RK A+ C LQ F I HS GGGTGSG + L++ L ++ + + Sbjct: 107 HYTIGKEIVDLVLDRIRKLADLCTGLQGFLIFHSFGGGTGSGFASLLMERLSVDYGKKSK 166 Query: 173 FVTSIYPSGE-DDVITSPYNSILAMKELNEHADCVLPIDNQSLFDIISK-IDLMVNSGKL 230 +IYP+ + + PYNSIL EH+DC +DN++++DI + +D+ Sbjct: 167 LEFAIYPAPQVSTAVVEPYNSILTTHTTLEHSDCAFMVDNEAIYDICRRNLDI------- 219 Query: 231 GTTVKPKSLVTSSSGALKKQHKKPFDAMNNIVANLLLNLTSSARFEGSLNMDLNEISMNL 290 + + +N ++ ++ ++T+S RF+G+LN+DL E NL Sbjct: 220 --------------------ERPTYTNLNRLIGQIVSSITASLRFDGALNVDLTEFQTNL 259 Query: 291 VPFPQLHYLVSSLTPLYTLTDVNIPPRRLDQMFSDAFSKDHQLLRADPKHSLYLACALMV 350 VP+P++H+ +++ P+ + + ++ + F +Q+++ DP+H Y+AC ++ Sbjct: 260 VPYPRIHFPLATYAPVISAEKAYHEQLSVAEITNACFEPANQMVKCDPRHGKYMACCMLY 319 Query: 351 RGNVQISDLRRNIERLKP--SLQFVSWNQEGWKTSLCSVPP--------VGHSHSLLALA 400 RG+V D+ I +K ++QFV W G+K + PP ++ L+ Sbjct: 320 RGDVVPKDVNAAIATIKTKRTIQFVDWCPTGFKVGINYQPPTVVPGGDLAKVQRAVCMLS 379 Query: 401 NNTCVKPTFMELKERFMRLYKKKAHLHHYLQVEGMEESCFTEAVSSLSALIQEYDQL 457 N T + + L +F +Y K+A +H Y+ EGMEE F+EA L+AL ++Y+++ Sbjct: 380 NTTAIAEAWARLDHKFDLMYAKRAFVHWYVG-EGMEEGEFSEAREDLAALEKDYEEV 435 >gi|17921993 tubulin, alpha 3c [Homo sapiens] Length = 450 Score = 230 bits (586), Expect = 2e-60 Identities = 140/477 (29%), Positives = 240/477 (50%), Gaps = 62/477 (12%) Query: 1 MTQSVVVQVGQCGNQIGCCFWDLALREHA--------AVNQKGIYDEAISSFFRNVDTRV 52 M + + + VGQ G QIG W+L EH + G D++ ++FF Sbjct: 1 MRECISIHVGQAGVQIGNACWELYCLEHGIQPDGQMPSDKTIGGGDDSFNTFFSET---- 56 Query: 53 VGDGGSISKGKICSLKARAVLIDMEEGVVNEILQGPLRDVFDTKQLITDISGSGNNWAVG 112 G G + RAV +D+E VV+E+ G R +F +QLIT + NN+A G Sbjct: 57 -GAGKHVP---------RAVFVDLEPTVVDEVRTGTYRQLFHPEQLITGKEDAANNYARG 106 Query: 113 HKVFGSLYQDQILEKFRKSAEHCDCLQCFFIIHSMGGGTGSGLGTFLLKVLEDEFPEVYR 172 H G D +L++ RK A+ C LQ F I HS GGGTGSG + L++ L ++ + + Sbjct: 107 HYTIGKEIVDLVLDRIRKLADLCTGLQGFLIFHSFGGGTGSGFASLLMERLSVDYGKKSK 166 Query: 173 FVTSIYPSGE-DDVITSPYNSILAMKELNEHADCVLPIDNQSLFDIISK-IDLMVNSGKL 230 +IYP+ + + PYNSIL EH+DC +DN++++DI + +D+ Sbjct: 167 LEFAIYPAPQVSTAVVEPYNSILTTHTTLEHSDCAFMVDNEAIYDICRRNLDI------- 219 Query: 231 GTTVKPKSLVTSSSGALKKQHKKPFDAMNNIVANLLLNLTSSARFEGSLNMDLNEISMNL 290 + + +N ++ ++ ++T+S RF+G+LN+DL E NL Sbjct: 220 --------------------ERPTYTNLNRLIGQIVSSITASLRFDGALNVDLTEFQTNL 259 Query: 291 VPFPQLHYLVSSLTPLYTLTDVNIPPRRLDQMFSDAFSKDHQLLRADPKHSLYLACALMV 350 VP+P++H+ +++ P+ + + ++ + F +Q+++ DP+H Y+AC ++ Sbjct: 260 VPYPRIHFPLATYAPVISAEKAYHEQLSVAEITNACFEPANQMVKCDPRHGKYMACCMLY 319 Query: 351 RGNVQISDLRRNIERLKP--SLQFVSWNQEGWKTSLCSVPP--------VGHSHSLLALA 400 RG+V D+ I +K ++QFV W G+K + PP ++ L+ Sbjct: 320 RGDVVPKDVNAAIATIKTKRTIQFVDWCPTGFKVGINYQPPTVVPGGDLAKVQRAVCMLS 379 Query: 401 NNTCVKPTFMELKERFMRLYKKKAHLHHYLQVEGMEESCFTEAVSSLSALIQEYDQL 457 N T + + L +F +Y K+A +H Y+ EGMEE F+EA L+AL ++Y+++ Sbjct: 380 NTTAIAEAWARLDHKFDLMYAKRAFVHWYVG-EGMEEGEFSEAREDLAALEKDYEEV 435 >gi|46409270 tubulin, alpha 3e [Homo sapiens] Length = 450 Score = 223 bits (567), Expect = 4e-58 Identities = 138/477 (28%), Positives = 238/477 (49%), Gaps = 62/477 (12%) Query: 1 MTQSVVVQVGQCGNQIGCCFWDLALREHA--------AVNQKGIYDEAISSFFRNVDTRV 52 M + + + VGQ G QIG W+L EH + G D++ ++FF Sbjct: 1 MRECISIHVGQAGVQIGNACWELYCLEHGIQPDGQMPSDKTIGGGDDSFNTFFSET---- 56 Query: 53 VGDGGSISKGKICSLKARAVLIDMEEGVVNEILQGPLRDVFDTKQLITDISGSGNNWAVG 112 G G + RAV +D+E VV+E+ G R +F +QLIT + +N+A G Sbjct: 57 -GAGKHVP---------RAVFVDLEPTVVDEVRTGTYRQLFHPEQLITGKEDAASNYARG 106 Query: 113 HKVFGSLYQDQILEKFRKSAEHCDCLQCFFIIHSMGGGTGSGLGTFLLKVLEDEFPEVYR 172 H G D +L++ RK A+ C LQ F I HS GGGTGSG + L++ L ++ + + Sbjct: 107 HYTIGKEIVDLVLDRIRKLADLCTGLQGFLIFHSFGGGTGSGFASLLMERLSVDYSKKSK 166 Query: 173 FVTSIYPSGE-DDVITSPYNSILAMKELNEHADCVLPIDNQSLFDIISK-IDLMVNSGKL 230 +IYP+ + + PYNSIL EH+DC +DN++++DI + +D+ Sbjct: 167 LEFAIYPAPQVSTAVVEPYNSILTTHTTLEHSDCAFMVDNEAIYDICRRNLDI------- 219 Query: 231 GTTVKPKSLVTSSSGALKKQHKKPFDAMNNIVANLLLNLTSSARFEGSLNMDLNEISMNL 290 + + +N ++ ++ ++T+S RF+G+LN+DL E NL Sbjct: 220 --------------------ERPTYTNLNRLIGQIVSSITASLRFDGALNVDLTEFQTNL 259 Query: 291 VPFPQLHYLVSSLTPLYTLTDVNIPPRRLDQMFSDAFSKDHQLLRADPKHSLYLACALMV 350 VP+P++H+ +++ P+ + + ++ + F +Q+++ DP+H Y+AC ++ Sbjct: 260 VPYPRIHFPLATYAPVISAEKAYHEQLSVAEITNACFEPANQMVKCDPRHGKYMACCMLY 319 Query: 351 RGNVQISDLRRNIERLKP--SLQFVSWNQEGWKTSLCSVPP--------VGHSHSLLALA 400 RG+V D+ I +K ++QFV W G+K + PP ++ L+ Sbjct: 320 RGDVVPKDVNAAIATIKTKRTIQFVDWCPTGFKVGINYQPPTVVPGGDLAKVQRAVCMLS 379 Query: 401 NNTCVKPTFMELKERFMRLYKKKAHLHHYLQVEGMEESCFTEAVSSLSALIQEYDQL 457 N T + + L +F +Y K A +H Y+ EGMEE F+EA L+AL ++ +++ Sbjct: 380 NTTAIAEAWARLVHKFDLMYAKWAFVHWYVG-EGMEEGEFSEAREDLAALEKDCEEV 435 >gi|13376181 tubulin, alpha-like 3 [Homo sapiens] Length = 446 Score = 221 bits (563), Expect = 1e-57 Identities = 143/473 (30%), Positives = 231/473 (48%), Gaps = 47/473 (9%) Query: 1 MTQSVVVQVGQCGNQIGCCFWDLALREHAAVNQKGIYDEAISSFFRNVDTRVVGDGGSIS 60 M + + + +GQ G QIG W+L EH + G+ + N Sbjct: 1 MRECLSIHIGQAGIQIGDACWELYCLEHG-IQPNGVVLDTQQDQLENAKMEHTNASFDTF 59 Query: 61 KGKICSLKA-----RAVLIDMEEGVVNEILQGPLRDVFDTKQLITDISGSGNNWAVGHKV 115 C +A RA+ +D+E V++ I G R +F +QL++ + NN+A G Sbjct: 60 ---FCETRAGKHVPRALFVDLEPTVIDGIRTGQHRSLFHPEQLLSGKEDAANNYARGRYS 116 Query: 116 FGSLYQDQILEKFRKSAEHCDCLQCFFIIHSMGGGTGSGLGTFLLKVLEDEFPEVYRFVT 175 GS D +LE+ RK AE C LQ F I S GGGTGSG + L++ L E+ + Sbjct: 117 VGSEVIDLVLERTRKLAEQCGGLQGFLIFRSFGGGTGSGFTSLLMERLTGEYSRKTKLEF 176 Query: 176 SIYPSGE-DDVITSPYNSILAMKELNEHADCVLPIDNQSLFDIISKIDLMVNSGKLGTTV 234 S+YP+ + PYNS+L EH DC +DN++++DI + KLG Sbjct: 177 SVYPAPRISTAVVEPYNSVLTTHSTTEHTDCTFMVDNEAVYDICHR--------KLGVEC 228 Query: 235 KPKSLVTSSSGALKKQHKKPFDAMNNIVANLLLNLTSSARFEGSLNMDLNEISMNLVPFP 294 + ++N +V ++ ++T+S RFEG LN+DL E NLVP+P Sbjct: 229 PSHA------------------SINRLVVQVVSSITASLRFEGPLNVDLIEFQTNLVPYP 270 Query: 295 QLHYLVSSLTPLYTLTDVNIPPRRLDQMFSDAFSKDHQLLRADPKHSLYLACALMVRGNV 354 ++H+ +++ P+ + + + + F +QL++ DP+ Y+AC L+ RG+V Sbjct: 271 RIHFPMTAFAPIVSADKAYHEQFSVSDITTACFESSNQLVKCDPRLGKYMACCLLYRGDV 330 Query: 355 QISDLRRNIERLKP--SLQFVSWNQEGWKTSLCSVPP-------VGHSH-SLLALANNTC 404 ++ I K S+QFV W G+K + + PP + H S+ L+N T Sbjct: 331 VPKEVNAAIAATKSRHSVQFVDWCPTGFKVGINNRPPTVMPGGDLAKVHRSICMLSNTTA 390 Query: 405 VKPTFMELKERFMRLYKKKAHLHHYLQVEGMEESCFTEAVSSLSALIQEYDQL 457 + + L +F +Y K+A LH YL+ EGMEE+ F EA L+AL ++Y+++ Sbjct: 391 IVEAWARLDHKFDLMYAKRAFLHWYLR-EGMEEAEFLEAREDLAALERDYEEV 442 >gi|31543831 tubulin, gamma 1 [Homo sapiens] Length = 451 Score = 171 bits (434), Expect = 1e-42 Identities = 134/470 (28%), Positives = 231/470 (49%), Gaps = 60/470 (12%) Query: 5 VVVQVGQCGNQIGCCFWDLALREHAAVNQKGIYDEAISSFFRNVDTRVVGDGGSISKGKI 64 + +Q+GQCGNQIG FW EH ++ +GI +E + D + V + + I Sbjct: 6 ITLQLGQCGNQIGFEFWKQLCAEHG-ISPEGIVEEFATE---GTDRKDVFFYQADDEHYI 61 Query: 65 CSLKARAVLIDMEEGVVNEILQGPLRDVFDTKQLITDI--SGSGNNWAVGHKVFGSLYQD 122 RAVL+D+E V++ IL P +++ + + G+GNNWA G +++D Sbjct: 62 ----PRAVLLDLEPRVIHSILNSPYAKLYNPENIYLSEHGGGAGNNWASGFSQGEKIHED 117 Query: 123 QILEKFRKSAEHCDCLQCFFIIHSMGGGTGSGLGTFLLKVLEDEFPEVYRFVTSIYPSGE 182 I + + A+ D L+ F + HS+ GGTGSGLG++LL+ L D +P+ S++P+ + Sbjct: 118 -IFDIIDREADGSDSLEGFVLCHSIAGGTGSGLGSYLLERLNDRYPKKLVQTYSVFPNQD 176 Query: 183 D--DVITSPYNSILAMKELNEHADCVLPIDNQSLFDIISKIDLMVNSGKLGTTVKPKSLV 240 + DV+ PYNS+L +K L ++ADCV+ +DN +L I Sbjct: 177 EMSDVVVQPYNSLLTLKRLTQNADCVVVLDNTALNRI----------------------- 213 Query: 241 TSSSGALKKQHKKPFDAMNNIVANLLLNLTSSARFEGSLNMDLNEISMNLVPFPQLHYLV 300 ++ L Q+ F +N +V+ ++ T++ R+ G +N DL + +L+P P+LH+L+ Sbjct: 214 --ATDRLHIQNPS-FSQINQLVSTIMSASTTTLRYPGYMNNDLIGLIASLIPTPRLHFLM 270 Query: 301 SSLTPLYT--------LTDVNIPPRRLDQMFSDAFSKDHQLLRADPKHSLYLACALMVRG 352 + TPL T T V RRL Q + S R + Y+A +++G Sbjct: 271 TGYTPLTTDQSVASVRKTTVLDVMRRLLQPKNVMVSTG----RDRQTNHCYIAILNIIQG 326 Query: 353 NVQISDLRRNIERLKPS--LQFVSWNQEGWKTSLCSVPPV---GHSHSLLALANNTCVKP 407 V + + ++++R++ F+ W + +L P H S L +AN+T + Sbjct: 327 EVDPTQVHKSLQRIRERKLANFIPWGPASIQVALSRKSPYLPSAHRVSGLMMANHTSISS 386 Query: 408 TFMELKERFMRLYKKKAHLHHYLQVEGMEESCFTEAVSS---LSALIQEY 454 F ++ +L K++A L + + E M + F E +S + LI EY Sbjct: 387 LFERTCRQYDKLRKREAFLEQF-RKEDMFKDNFDEMDTSREIVQQLIDEY 435 >gi|7706751 tubulin, gamma 2 [Homo sapiens] Length = 451 Score = 170 bits (431), Expect = 2e-42 Identities = 135/470 (28%), Positives = 229/470 (48%), Gaps = 60/470 (12%) Query: 5 VVVQVGQCGNQIGCCFWDLALREHAAVNQKGIYDEAISSFFRNVDTRVVGDGGSISKGKI 64 + +Q+GQCGNQIG FW EH ++ +GI +E + D + V + + I Sbjct: 6 ITLQLGQCGNQIGFEFWKQLCAEHG-ISPEGIVEEFATE---GTDRKDVFFYQADDEHYI 61 Query: 65 CSLKARAVLIDMEEGVVNEILQGPLRDVFDTKQLITDI--SGSGNNWAVGHKVFGSLYQD 122 RAVL+D+E V++ IL P +++ + + G+GNNWA G +++D Sbjct: 62 ----PRAVLLDLEPRVIHSILNSPYAKLYNPENIYLSEHGGGAGNNWASGFSQGEKIHED 117 Query: 123 QILEKFRKSAEHCDCLQCFFIIHSMGGGTGSGLGTFLLKVLEDEFPEVYRFVTSIYPSGE 182 I + + A+ D L+ F + HS+ GGTGSGLG++LL+ L D +P+ S++P + Sbjct: 118 -IFDIIDREADGSDSLEGFVLCHSIAGGTGSGLGSYLLERLNDRYPKKLVQTYSVFPYQD 176 Query: 183 D--DVITSPYNSILAMKELNEHADCVLPIDNQSLFDIISKIDLMVNSGKLGTTVKPKSLV 240 + DV+ PYNS+L +K L ++ADCV+ +DN +L I Sbjct: 177 EMSDVVVQPYNSLLTLKRLTQNADCVVVLDNTALNRI----------------------- 213 Query: 241 TSSSGALKKQHKKPFDAMNNIVANLLLNLTSSARFEGSLNMDLNEISMNLVPFPQLHYLV 300 ++ L Q+ F +N +V+ ++ T++ R+ G +N DL + +L+P P+LH+L+ Sbjct: 214 --ATDRLHIQNPS-FSQINQLVSTIMSASTTTLRYPGYMNNDLIGLIASLIPTPRLHFLM 270 Query: 301 SSLTPLYT--------LTDVNIPPRRLDQMFSDAFSKDHQLLRADPKHSLYLACALMVRG 352 + TPL T T V RRL Q + S R + Y+A +++G Sbjct: 271 TGYTPLTTDQSVASVRKTTVLDVMRRLLQPKNVMVSTG----RDRQTNHCYIAILNIIQG 326 Query: 353 NVQISDLRRNIERLKPS--LQFVSWNQEGWKTSLCSVPPV---GHSHSLLALANNTCVKP 407 V + + ++++R++ F+ W + +L P H S L +AN+T + Sbjct: 327 EVDPTQVHKSLQRIRERKLANFIPWGPASIQVALSRKSPYLPSAHRVSGLMMANHTSISS 386 Query: 408 TFMELKERFMRLYKKKAHLHHYLQVEGMEESCFTEAVSS---LSALIQEY 454 F ++F +L K+ A L + + E M + F E S + LI EY Sbjct: 387 LFESSCQQFDKLRKRDAFLEQF-RKEDMFKDNFDEMDRSREVVQELIDEY 435 >gi|50592998 delta-tubulin [Homo sapiens] Length = 453 Score = 134 bits (336), Expect = 2e-31 Identities = 129/482 (26%), Positives = 212/482 (43%), Gaps = 61/482 (12%) Query: 5 VVVQVGQCGNQIGCCFWDLALREHAAVNQKGIYDEAISSFFRNVDTRVVGDGGSISKGKI 64 V VQ+GQCGNQIG +D L + + + + S N + S+ + Sbjct: 4 VTVQLGQCGNQIGFEVFDALLSDSHS-------SQGLCSMRENEAYQASCKERFFSEEEN 56 Query: 65 CSLKARAVLIDMEEGVVNEILQGPLRD---VFDTKQLITDISGSGNNWAVGHKVFGSLYQ 121 ARAVL+DME V+N++L + + GSGNNWA G+ V G ++ Sbjct: 57 GVPIARAVLVDMEPKVINQMLSKAAQSGQWKYGQHACFCQKQGSGNNWAYGYSVHGPRHE 116 Query: 122 DQILEKFRKSAEHCDCLQCFFIIHSMGGGTGSGLGTFLLKVLEDEFPEVYRFVTSIYPSG 181 + I+ RK E CD FFII SM GGTGSGLG F+ + LED++ + I+P G Sbjct: 117 ESIMNIIRKEVEKCDSFSGFFIIMSMAGGTGSGLGAFVTQNLEDQYSNSLKMNQIIWPYG 176 Query: 182 EDDVITSPYNSILAMKELNEHADCVLPIDNQSLFDIISKI---------DL-MVNSGKLG 231 +VI YNSIL + L +D +L +N ++ I +K+ D+ V + +LG Sbjct: 177 TGEVIVQNYNSILTLSHLYRSSDALLLHENDAIHKICAKLMNIKQISFSDINQVLAHQLG 236 Query: 232 TTVKPKSLVTSSSGALKKQHKKPFDAMNNIVANLLLNLTSSARFEGSLNMDLNEISMNLV 291 + +P SS F N + +L+ +L F+ ++ +S N + Sbjct: 237 SVFQPTYSAESS-----------FHYRRNPLGDLMEHLVPHPEFKMLSVRNIPHMSENSL 285 Query: 292 PF---------PQLHYLVSSLTPLYTLTDVNIPPRRLDQMFSDAFSKDHQLLRADPKHSL 342 + L ++ S + D ++ P S L D + Sbjct: 286 AYTTFTWAGLLKHLRQMLISNAKMEEGIDRHVWP-----PLSGLPPLSKMSLNKDLHFNT 340 Query: 343 YLACALMVRG-NVQISDLRRNIERLKPSLQFVSWNQ-----EGWKTSLCSVPPVGHSHSL 396 +A +++RG +VQ +D +E K + SW + WKT + S Sbjct: 341 SIANLVILRGKDVQSAD----VEGFKDPALYTSWLKPVNAFNVWKTQRAFSK---YEKSA 393 Query: 397 LALANNT-CVKPTFMELKERFMRLYKKKAHLHHYLQVEGMEESCFTEAVSSLSALIQEYD 455 + ++N+ VKP M + + ++ KA++H Y + G+EE F ++ +SL ++ Y Sbjct: 394 VLVSNSQFLVKPLDM-IVGKAWNMFASKAYIHQYTKF-GIEEEDFLDSFTSLEQVVASYC 451 Query: 456 QL 457 L Sbjct: 452 NL 453 >gi|239756254 PREDICTED: similar to tubulin, beta 5 [Homo sapiens] Length = 365 Score = 92.4 bits (228), Expect = 8e-19 Identities = 82/337 (24%), Positives = 149/337 (44%), Gaps = 51/337 (15%) Query: 130 KSAEHCDCLQCFFIIHSMGGGTGSGLGTFLLKVLEDEFPEVYRFVTSIYPSGED-DVITS 188 K AE CDCLQ F + HS+G GTGSG+GT L + +E P+ +S+ PS + + Sbjct: 58 KEAESCDCLQGFQLTHSLGEGTGSGMGTLLHSKIREEDPDHIMNTSSVMPSLKVFGTVAE 117 Query: 189 PYNSILAMKELNEHADCVLPIDNQSLFDIISKIDLMVNSGKLGTTVKPKSLVTSSSGALK 248 P ++ L + L E+ D D ++ ++I + L T + Sbjct: 118 PCSAXLPIHPLVENTDETCGTDIEAPYNI---------------RFRTLELTTQN----- 157 Query: 249 KQHKKPFDAMNNIVANLLLNLTSSARFEGSLNMDLNEISMNLVPFPQLHYLVSSLTPLYT 308 ++ + + V+ + +T+ F LN DL ++++N V FP+L + +++ PL + Sbjct: 158 ------YEDLTHXVSANMRGVTTFLCFPHQLNSDLCKLAVNTVSFPRLQFFMATFAPLTS 211 Query: 309 ----LTDVNIPPRRLDQMFSDAFSKDHQLLRADPKHSLYLACALMVRGNV-----QISDL 359 L P+ Q+F D K+ + L N+ ++++ Sbjct: 212 CGSQLYRALTMPKLTQQVF-------------DAKNMMAAPPGLPSSMNIHPFMKEVNEQ 258 Query: 360 RRNIERLKPSLQFVSWNQEGWKTSLCSVPPVGHSHSLLALANNTCVKPTFMELKERFMRL 419 +++ S F+ W KT++ + P GH ++ + N+ + M ++F + Sbjct: 259 MLSVQNKSASSYFMEWMLTTVKTAMWDILPHGHKMAVTFVGNSAATQKLSM-ASQQFPAV 317 Query: 420 YKKKAHLHHYLQVEGMEESCFTEAVSSLSALIQEYDQ 456 KA LH Y EGM E F EA ++++ I E+ Q Sbjct: 318 LCGKAVLHWYAG-EGMNEMEFAEAENNMNDFISEHRQ 353 >gi|239750785 PREDICTED: similar to tubulin, beta 5 [Homo sapiens] Length = 365 Score = 92.4 bits (228), Expect = 8e-19 Identities = 82/337 (24%), Positives = 149/337 (44%), Gaps = 51/337 (15%) Query: 130 KSAEHCDCLQCFFIIHSMGGGTGSGLGTFLLKVLEDEFPEVYRFVTSIYPSGED-DVITS 188 K AE CDCLQ F + HS+G GTGSG+GT L + +E P+ +S+ PS + + Sbjct: 58 KEAESCDCLQGFQLTHSLGEGTGSGMGTLLHSKIREEDPDHIMNTSSVMPSLKVFGTVAE 117 Query: 189 PYNSILAMKELNEHADCVLPIDNQSLFDIISKIDLMVNSGKLGTTVKPKSLVTSSSGALK 248 P ++ L + L E+ D D ++ ++I + L T + Sbjct: 118 PCSAXLPIHPLVENTDETCGTDIEAPYNI---------------RFRTLELTTQN----- 157 Query: 249 KQHKKPFDAMNNIVANLLLNLTSSARFEGSLNMDLNEISMNLVPFPQLHYLVSSLTPLYT 308 ++ + + V+ + +T+ F LN DL ++++N V FP+L + +++ PL + Sbjct: 158 ------YEDLTHXVSANMRGVTTFLCFPHQLNSDLCKLAVNTVSFPRLQFFMATFAPLTS 211 Query: 309 ----LTDVNIPPRRLDQMFSDAFSKDHQLLRADPKHSLYLACALMVRGNV-----QISDL 359 L P+ Q+F D K+ + L N+ ++++ Sbjct: 212 CGSQLYRALTMPKLTQQVF-------------DAKNMMAAPPGLPSSMNIHPFMKEVNEQ 258 Query: 360 RRNIERLKPSLQFVSWNQEGWKTSLCSVPPVGHSHSLLALANNTCVKPTFMELKERFMRL 419 +++ S F+ W KT++ + P GH ++ + N+ + M ++F + Sbjct: 259 MLSVQNKSASSYFMEWMLTTVKTAMWDILPHGHKMAVTFVGNSAATQKLSM-ASQQFPAV 317 Query: 420 YKKKAHLHHYLQVEGMEESCFTEAVSSLSALIQEYDQ 456 KA LH Y EGM E F EA ++++ I E+ Q Sbjct: 318 LCGKAVLHWYAG-EGMNEMEFAEAENNMNDFISEHRQ 353 >gi|169178090 PREDICTED: similar to hCG1784562 [Homo sapiens] Length = 316 Score = 58.9 bits (141), Expect = 1e-08 Identities = 40/145 (27%), Positives = 69/145 (47%), Gaps = 7/145 (4%) Query: 315 PPRRLDQMFSDAFSKDHQLLRADPKHSLYLACALMVRGNV---QISDLRRNIERLKPSLQ 371 PP + ++ F + L DP H YL A +V G + ++ + NI+ K S Sbjct: 174 PPLEVSKLTKQMFDAKNMLAACDPCHGCYLMAAPIVGGCMSMREVDEQTYNIQN-KYSSY 232 Query: 372 FVSWNQEGWKTSLCSVPPVGHSHSLLALANNTCVKPTFME--LKERFMRLYKKKAHLHHY 429 F W + + C +PP+ S+ ++NNT ++ F + E+F ++ KA L Y Sbjct: 233 FAHWIPHNVERAACDIPPLELKMSVTFISNNTAIQELFRFRCILEQFTAKFRCKAFLSWY 292 Query: 430 LQVEGMEESCFTEAVSSLSALIQEY 454 +GM + F E S+++ L+ EY Sbjct: 293 -SGKGMHDVEFAEVESNMNNLVSEY 316 >gi|169179398 PREDICTED: similar to hCG1784562 [Homo sapiens] Length = 316 Score = 58.9 bits (141), Expect = 1e-08 Identities = 40/145 (27%), Positives = 69/145 (47%), Gaps = 7/145 (4%) Query: 315 PPRRLDQMFSDAFSKDHQLLRADPKHSLYLACALMVRGNV---QISDLRRNIERLKPSLQ 371 PP + ++ F + L DP H YL A +V G + ++ + NI+ K S Sbjct: 174 PPLEVSKLTKQMFDAKNMLAACDPCHGCYLMAAPIVGGCMSMREVDEQTYNIQN-KYSSY 232 Query: 372 FVSWNQEGWKTSLCSVPPVGHSHSLLALANNTCVKPTFME--LKERFMRLYKKKAHLHHY 429 F W + + C +PP+ S+ ++NNT ++ F + E+F ++ KA L Y Sbjct: 233 FAHWIPHNVERAACDIPPLELKMSVTFISNNTAIQELFRFRCILEQFTAKFRCKAFLSWY 292 Query: 430 LQVEGMEESCFTEAVSSLSALIQEY 454 +GM + F E S+++ L+ EY Sbjct: 293 -SGKGMHDVEFAEVESNMNNLVSEY 316 >gi|169181282 PREDICTED: similar to hCG1784562 [Homo sapiens] Length = 316 Score = 58.9 bits (141), Expect = 1e-08 Identities = 40/145 (27%), Positives = 69/145 (47%), Gaps = 7/145 (4%) Query: 315 PPRRLDQMFSDAFSKDHQLLRADPKHSLYLACALMVRGNV---QISDLRRNIERLKPSLQ 371 PP + ++ F + L DP H YL A +V G + ++ + NI+ K S Sbjct: 174 PPLEVSKLTKQMFDAKNMLAACDPCHGCYLMAAPIVGGCMSMREVDEQTYNIQN-KYSSY 232 Query: 372 FVSWNQEGWKTSLCSVPPVGHSHSLLALANNTCVKPTFME--LKERFMRLYKKKAHLHHY 429 F W + + C +PP+ S+ ++NNT ++ F + E+F ++ KA L Y Sbjct: 233 FAHWIPHNVERAACDIPPLELKMSVTFISNNTAIQELFRFRCILEQFTAKFRCKAFLSWY 292 Query: 430 LQVEGMEESCFTEAVSSLSALIQEY 454 +GM + F E S+++ L+ EY Sbjct: 293 -SGKGMHDVEFAEVESNMNNLVSEY 316 >gi|94721261 2',3'-cyclic nucleotide 3' phosphodiesterase [Homo sapiens] Length = 421 Score = 32.3 bits (72), Expect = 0.96 Identities = 20/66 (30%), Positives = 34/66 (51%), Gaps = 1/66 (1%) Query: 306 LYTLTDVNIPPRRLDQMFSDAFSKDHQLLRADPKHSLYLACALMVRGNVQISDLRRNIER 365 + L D N RL+Q+F A +Q++ +PK + L CA + N Q ++++ Sbjct: 118 ILVLDDTNHERERLEQLFEMADQYQYQVVLVEPKTAWRLDCAQLKEKN-QWQLSADDLKK 176 Query: 366 LKPSLQ 371 LKP L+ Sbjct: 177 LKPGLE 182 >gi|39780571 misato [Homo sapiens] Length = 570 Score = 32.3 bits (72), Expect = 0.96 Identities = 25/95 (26%), Positives = 43/95 (45%), Gaps = 6/95 (6%) Query: 120 YQDQILEKFRKSAEHCDCLQCFFIIHSMGGGTGSGLGTFLLKVLEDEFPE----VYRFVT 175 YQ+++ ++ E CD LQ F I+ + G SG+G ++L+DE+ + + Sbjct: 207 YQEELEDRLHFYVEECDYLQGFQILCDLHDGF-SGVGAKAAELLQDEYSGRGIITWGLLP 265 Query: 176 SIYPSGE-DDVITSPYNSILAMKELNEHADCVLPI 209 Y GE I N+ + L H+ V P+ Sbjct: 266 GPYHRGEAQRNIYRLLNTAFGLVHLTAHSSLVCPL 300 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.320 0.135 0.400 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 17,286,241 Number of Sequences: 37866 Number of extensions: 745647 Number of successful extensions: 1786 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 26 Number of HSP's successfully gapped in prelim test: 14 Number of HSP's that attempted gapping in prelim test: 1620 Number of HSP's gapped (non-prelim): 53 length of query: 475 length of database: 18,247,518 effective HSP length: 106 effective length of query: 369 effective length of database: 14,233,722 effective search space: 5252243418 effective search space used: 5252243418 T: 11 A: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.8 bits) S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.