Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Search of human proteins with 13994322
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|13994322 TBC1 domain family, member 10A [Homo sapiens]
(508 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|13994322 TBC1 domain family, member 10A [Homo sapiens] 1038 0.0
gi|167614488 TBC1 domain family, member 10B [Homo sapiens] 575 e-164
gi|38348348 TBC1 domain family, member 10C [Homo sapiens] 399 e-111
gi|78217386 RAB GTPase activating protein 1-like isoform A [Homo... 155 8e-38
gi|164519084 RAB GTPase activating protein 1 [Homo sapiens] 140 2e-33
gi|118722351 growth hormone regulated TBC protein 1 [Homo sapiens] 137 2e-32
gi|7661864 USP6 N-terminal like isoform 1 [Homo sapiens] 136 5e-32
gi|122937432 USP6 N-terminal like isoform 2 [Homo sapiens] 136 5e-32
gi|229577000 ecotropic viral integration site 5-like isoform 1 [... 135 7e-32
gi|21687020 ecotropic viral integration site 5-like isoform 2 [H... 135 7e-32
gi|68299759 ecotropic viral integration site 5 [Homo sapiens] 129 5e-30
gi|156231067 TBC1 domain family, member 8 [Homo sapiens] 128 1e-29
gi|45597177 TBC1 domain family, member 9B (with GRAM domain) iso... 127 3e-29
gi|45597175 TBC1 domain family, member 9B (with GRAM domain) iso... 127 3e-29
gi|38570101 TBC1 domain family, member 8B (with GRAM domain) iso... 127 3e-29
gi|29648315 small G protein signaling modulator 3 [Homo sapiens] 126 5e-29
gi|139394668 TBC1 domain family, member 9 (with GRAM domain) [Ho... 125 9e-29
gi|194018478 TBC1 domain family, member 2B isoform a [Homo sapiens] 122 1e-27
gi|114688046 TBC1 domain family, member 4 [Homo sapiens] 117 2e-26
gi|194018476 TBC1 domain family, member 2B isoform b [Homo sapiens] 117 2e-26
gi|50658061 TBC1 (tre-2/USP6, BUB2, cdc16) domain family, member... 113 5e-25
gi|109638751 ubiquitin specific protease 6 [Homo sapiens] 110 4e-24
gi|222352143 TBC1 domain family, member 2 [Homo sapiens] 109 5e-24
gi|226693407 TBC1 domain family, member 3H [Homo sapiens] 105 7e-23
gi|14149985 TBC1 domain family, member 3F [Homo sapiens] 105 7e-23
gi|157502205 TBC1 domain family, member 3G [Homo sapiens] 105 7e-23
gi|183583565 TBC1 domain family, member 3 [Homo sapiens] 105 1e-22
gi|183583567 TBC1 domain family, member 3E [Homo sapiens] 105 1e-22
gi|183583563 TBC1 domain family, member 3D [Homo sapiens] 105 1e-22
gi|90577185 TBC1 domain family member 3C [Homo sapiens] 104 2e-22
>gi|13994322 TBC1 domain family, member 10A [Homo sapiens]
Length = 508
Score = 1038 bits (2685), Expect = 0.0
Identities = 508/508 (100%), Positives = 508/508 (100%)
Query: 1 MAKSNGENGPRAPAAGESLSGTRESLAQGPDAATTDELSSLGSDSEANGFAERRIDKFGF 60
MAKSNGENGPRAPAAGESLSGTRESLAQGPDAATTDELSSLGSDSEANGFAERRIDKFGF
Sbjct: 1 MAKSNGENGPRAPAAGESLSGTRESLAQGPDAATTDELSSLGSDSEANGFAERRIDKFGF 60
Query: 61 IVGSQGAEGALEEVPLEVLRQRESKWLDMLNNWDKWMAKKHKKIRLRCQKGIPPSLRGRA 120
IVGSQGAEGALEEVPLEVLRQRESKWLDMLNNWDKWMAKKHKKIRLRCQKGIPPSLRGRA
Sbjct: 61 IVGSQGAEGALEEVPLEVLRQRESKWLDMLNNWDKWMAKKHKKIRLRCQKGIPPSLRGRA 120
Query: 121 WQYLSGGKVKLQQNPGKFDELDMSPGDPKWLDVIERDLHRQFPFHEMFVSRGGHGQQDLF 180
WQYLSGGKVKLQQNPGKFDELDMSPGDPKWLDVIERDLHRQFPFHEMFVSRGGHGQQDLF
Sbjct: 121 WQYLSGGKVKLQQNPGKFDELDMSPGDPKWLDVIERDLHRQFPFHEMFVSRGGHGQQDLF 180
Query: 181 RVLKAYTLYRPEEGYCQAQAPIAAVLLMHMPAEQAFWCLVQICEKYLPGYYSEKLEAIQL 240
RVLKAYTLYRPEEGYCQAQAPIAAVLLMHMPAEQAFWCLVQICEKYLPGYYSEKLEAIQL
Sbjct: 181 RVLKAYTLYRPEEGYCQAQAPIAAVLLMHMPAEQAFWCLVQICEKYLPGYYSEKLEAIQL 240
Query: 241 DGEILFSLLQKVSPVAHKHLSRQKIDPLLYMTEWFMCAFSRTLPWSSVLRVWDMFFCEGV 300
DGEILFSLLQKVSPVAHKHLSRQKIDPLLYMTEWFMCAFSRTLPWSSVLRVWDMFFCEGV
Sbjct: 241 DGEILFSLLQKVSPVAHKHLSRQKIDPLLYMTEWFMCAFSRTLPWSSVLRVWDMFFCEGV 300
Query: 301 KIIFRVGLVLLKHALGSPEKVKACQGQYETIERLRSLSPKIMQEAFLVQEVVELPVTERQ 360
KIIFRVGLVLLKHALGSPEKVKACQGQYETIERLRSLSPKIMQEAFLVQEVVELPVTERQ
Sbjct: 301 KIIFRVGLVLLKHALGSPEKVKACQGQYETIERLRSLSPKIMQEAFLVQEVVELPVTERQ 360
Query: 361 IEREHLIQLRRWQETRGELQCRSPPRLHGAKAILDAEPGPRPALQPSPSIRLPLDAPLPG 420
IEREHLIQLRRWQETRGELQCRSPPRLHGAKAILDAEPGPRPALQPSPSIRLPLDAPLPG
Sbjct: 361 IEREHLIQLRRWQETRGELQCRSPPRLHGAKAILDAEPGPRPALQPSPSIRLPLDAPLPG 420
Query: 421 SKAKPKPPKQAQKEQRKQMKGRGQLEKPPAPNQAMVVAAAGDACPPQHVPPKDSAPKDSA 480
SKAKPKPPKQAQKEQRKQMKGRGQLEKPPAPNQAMVVAAAGDACPPQHVPPKDSAPKDSA
Sbjct: 421 SKAKPKPPKQAQKEQRKQMKGRGQLEKPPAPNQAMVVAAAGDACPPQHVPPKDSAPKDSA 480
Query: 481 PQDLAPQVSAHHRSQESLTSQESEDTYL 508
PQDLAPQVSAHHRSQESLTSQESEDTYL
Sbjct: 481 PQDLAPQVSAHHRSQESLTSQESEDTYL 508
>gi|167614488 TBC1 domain family, member 10B [Homo sapiens]
Length = 808
Score = 575 bits (1483), Expect = e-164
Identities = 290/507 (57%), Positives = 361/507 (71%), Gaps = 28/507 (5%)
Query: 6 GENGPRAPAAGESLSGTRESLAQGPDAATTDELSSLGSDSEANGFAERRIDKFGFIVGSQ 65
G +GPR A SL G + D++SS+GSDSE NG A R+ DK+GF+ GSQ
Sbjct: 255 GISGPRGQAPDTLSYLDSVSLMSGTLESLADDVSSMGSDSEINGLALRKTDKYGFLGGSQ 314
Query: 66 GAEGALEEVPLEVLRQRESKWLDMLNNWDKWMAKKHKKIRLRCQKGIPPSLRGRAWQYLS 125
+ +P++V RQRE KWLDM +NWDKW++++ +K++LRC+KGIP SLR +AWQYLS
Sbjct: 315 YSGSLESSIPVDVARQRELKWLDMFSNWDKWLSRRFQKVKLRCRKGIPSSLRAKAWQYLS 374
Query: 126 GGKVKLQQNPGKFDELDMSPGDPKWLDVIERDLHRQFPFHEMFVSRGGHGQQDLFRVLKA 185
K L+QNPGKF+EL+ +PGDPKWLDVIE+DLHRQFPFHEMF +RGGHGQQDL+R+LKA
Sbjct: 375 NSKELLEQNPGKFEELERAPGDPKWLDVIEKDLHRQFPFHEMFAARGGHGQQDLYRILKA 434
Query: 186 YTLYRPEEGYCQAQAPIAAVLLMHMPAEQAFWCLVQICEKYLPGYYSEKLEAIQLDGEIL 245
YT+YRP+EGYCQAQAP+AAVLLMHMPAEQAFWCLVQIC+KYLPGYYS LEAIQLDGEI
Sbjct: 435 YTIYRPDEGYCQAQAPVAAVLLMHMPAEQAFWCLVQICDKYLPGYYSAGLEAIQLDGEIF 494
Query: 246 FSLLQKVSPVAHKHLSRQKIDPLLYMTEWFMCAFSRTLPWSSVLRVWDMFFCEGVKIIFR 305
F+LL++ SP+AH+HL RQ+IDP+LYMTEWFMC F+RTLPW+SVLRVWDMFFCEGVKIIFR
Sbjct: 495 FALLRRASPLAHRHLRRQRIDPVLYMTEWFMCIFARTLPWASVLRVWDMFFCEGVKIIFR 554
Query: 306 VGLVLLKHALGSPEKVKACQGQYETIERLRSLSPKIMQEAFLVQEVVELPVTERQIEREH 365
V LVLL+H LGS EK+++CQG YET+E+LR+L + MQE FLV EV LPVTE IERE+
Sbjct: 555 VALVLLRHTLGSVEKLRSCQGMYETMEQLRNLPQQCMQEDFLVHEVTNLPVTEALIEREN 614
Query: 366 LIQLRRWQETRGELQCRSPPRLHGAKAILDAEPGPRPALQPSPSIRLPLDAPLPGSKAK- 424
QL++W+ETRGELQ R RLHG++AI + +P L PS S+ LPG K++
Sbjct: 615 AAQLKKWRETRGELQYRPSRRLHGSRAIHEERRRQQPPLGPSSSL-----LSLPGLKSRG 669
Query: 425 -------PKPPKQAQKEQRKQMKGRGQLEKPPAPNQAMVVAAAGDACPPQHVPPKDSAPK 477
P PP ++ PAP VV A G P P +S P
Sbjct: 670 SRAAGGAPSPPPPVRR-----------ASAGPAPGP--VVTAEG-LHPSLPSPTGNSTPL 715
Query: 478 DSAPQDLAPQVSAHHRSQESLTSQESE 504
S+ ++ Q + ++ QE E
Sbjct: 716 GSS-KETRKQEKERQKQEKERQKQEKE 741
>gi|38348348 TBC1 domain family, member 10C [Homo sapiens]
Length = 446
Score = 399 bits (1026), Expect = e-111
Identities = 205/439 (46%), Positives = 292/439 (66%), Gaps = 18/439 (4%)
Query: 24 ESLAQGPDAATTDELSSLGSDSEANGFAE-RRIDKFGFIVGSQGAEGALEEVPLEVLRQR 82
E L Q P+ D+ SSLGSDSE +G R+ D++GFI GS AE P +++RQR
Sbjct: 7 EDLVQPPELQ--DDSSSLGSDSELSGPGPYRQADRYGFIGGSS-AEPGPGHPPADLIRQR 63
Query: 83 ESKWLDMLNNWDKWMAKKHKKIRLRCQKGIPPSLRGRAWQYLSGGKVKLQQNPGKFDELD 142
E KW++M ++W+K M++++KK++++C+KGIP +LR R W L G V + +PG + EL
Sbjct: 64 EMKWVEMTSHWEKTMSRRYKKVKMQCRKGIPSALRARCWPLLCGAHVCQKNSPGTYQELA 123
Query: 143 MSPGDPKWLDVIERDLHRQFPFHEMFVSRGGHGQQDLFRVLKAYTLYRPEEGYCQAQAPI 202
+PGDP+W++ I RDLHRQFP HEMFVS GHGQQ L +VLKAYTLYRPE+GYCQAQ P+
Sbjct: 124 EAPGDPQWMETIGRDLHRQFPLHEMFVSPQGHGQQGLLQVLKAYTLYRPEQGYCQAQGPV 183
Query: 203 AAVLLMHMPAEQAFWCLVQICEKYLPGYYSEKLEAIQLDGEILFSLLQKVSPVAHKHLSR 262
AAVLLMH+P E+AFWCLVQICE YLPGYY +EA++LD E+ +LL+++ P HKHL +
Sbjct: 184 AAVLLMHLPPEEAFWCLVQICEVYLPGYYGPHMEAVRLDAEVFMALLRRLLPHVHKHLQQ 243
Query: 263 QKIDPLLYMTEWFMCAFSRTLPWSSVLRVWDMFFCEGVKIIFRVGLVLLKHALGSPEKVK 322
+ PLLY+ EWF+C F+R+LP+ +VLRVWD F EG +++FRVGL L++ ALG+ E+
Sbjct: 244 VGVGPLLYLPEWFLCLFARSLPFPTVLRVWDAFLSEGARVLFRVGLTLVRLALGTAEQRG 303
Query: 323 ACQGQYETIERLRSLSPKIMQEAFLVQEVVELPVTERQIEREHLIQLRRWQETRGELQCR 382
AC G ET+ LR++ P +QE + +V + ++ER ++RE QL + ++ R
Sbjct: 304 ACPGLLETLGALRAIPPAQLQEEAFMSQVHSVVLSERDLQREIKAQLAQLPDSAPGPPPR 363
Query: 383 SPPRLHGAKAILDAE--PGPRPALQPSPSIRLPLDAPLPGSKAKPKPPKQAQKEQRKQMK 440
RL GA+AI +A+ G R +P R+ + P +P+PP++ + + K
Sbjct: 364 PQVRLAGAQAIFEAQQLAGVRRGAKPEVP-RIVVQPP-----EEPRPPRRKPQTRGKTFH 417
Query: 441 G-----RG-QLEKPPAPNQ 453
G RG +E PP P +
Sbjct: 418 GLLTRARGPPIEGPPRPQR 436
>gi|78217386 RAB GTPase activating protein 1-like isoform A [Homo
sapiens]
Length = 815
Score = 155 bits (392), Expect = 8e-38
Identities = 101/315 (32%), Positives = 150/315 (47%), Gaps = 19/315 (6%)
Query: 1 MAKSNGENGPRA-PAAGESLSGTRESLAQGPDAATTDELSSLGSDSEANGFAERRIDKFG 59
+ +S G+ A A E +S RES + P T+ D EA ++ +
Sbjct: 439 LKQSEGKGHTNAGDAIYEVVSLQRESDKEEPVTPTSGGGPMSPQDDEAEEESDNEL---- 494
Query: 60 FIVGSQGAEGALEEVPLEVLRQRESKWLDMLNNWDKWMAKKHKKIRLRCQKGIPPSLRGR 119
S G ++ P ++L W ++L W + + K + + G+P +LR
Sbjct: 495 ----SSGTGDVSKDCPEKILYS----WGELLGKWHSNLGARPKGLSTLVKSGVPEALRAE 546
Query: 120 AWQYLSGGKVKLQQNPGKFDELD-MSPGDPKWLDVIERDLHRQFPFHEMFVSRGGHGQQD 178
WQ L+G N D + D VI RD+HR FP H+ F GG GQ+
Sbjct: 547 VWQLLAG----CHDNQAMLDRYRILITKDSAQESVITRDIHRTFPAHDYFKDTGGDGQES 602
Query: 179 LFRVLKAYTLYRPEEGYCQAQAPIAAVLLMHMPAEQAFWCLVQICEKY-LPGYYSEKLEA 237
L+++ KAY++Y + GYCQ Q+ +AAVLL+HMP EQAF LV+I Y L Y E
Sbjct: 603 LYKICKAYSVYDEDIGYCQGQSFLAAVLLLHMPEEQAFCVLVKIMYDYGLRDLYRNNFED 662
Query: 238 IQLDGEILFSLLQKVSPVAHKHLSRQKIDPLLYMTEWFMCAFSRTLPWSSVLRVWDMFFC 297
+ L L+Q+ P H H S ++ +Y ++WF+ F+ P V + D+ C
Sbjct: 663 LHCKFYQLERLMQEQLPDLHSHFSDLNLEAHMYASQWFLTLFTAKFPLCMVFHIIDLLLC 722
Query: 298 EGVKIIFRVGLVLLK 312
EG+ IIF V L LLK
Sbjct: 723 EGLNIIFHVALALLK 737
>gi|164519084 RAB GTPase activating protein 1 [Homo sapiens]
Length = 1069
Score = 140 bits (354), Expect = 2e-33
Identities = 80/233 (34%), Positives = 123/233 (52%), Gaps = 14/233 (6%)
Query: 86 WLDMLNNWDKWMAKKHKKIRLRCQKGIPPSLRGRAWQYLSGGKVKLQQNPGKFDELDM-- 143
W ++L+ W + + K++ + G+P +LRG WQ L+G N ++ +
Sbjct: 541 WGELLSKWHLNLNVRPKQLSSLVRNGVPEALRGEVWQLLAG----CHNNDHLVEKYRILI 596
Query: 144 ---SPGDPKWLDVIERDLHRQFPFHEMFVSRGGHGQQDLFRVLKAYTLYRPEEGYCQAQA 200
SP D I RD++R FP H+ F GG GQ L+++ KAY++Y E GYCQ Q+
Sbjct: 597 TKESPQD----SAITRDINRTFPAHDYFKDTGGDGQDSLYKICKAYSVYDEEIGYCQGQS 652
Query: 201 PIAAVLLMHMPAEQAFWCLVQICEKY-LPGYYSEKLEAIQLDGEILFSLLQKVSPVAHKH 259
+AAVLL+HMP EQAF LV+I Y L + + E + L L+Q+ P + H
Sbjct: 653 FLAAVLLLHMPEEQAFSVLVKIMFDYGLRELFKQNFEDLHCKFYQLERLMQEYIPDLYNH 712
Query: 260 LSRQKIDPLLYMTEWFMCAFSRTLPWSSVLRVWDMFFCEGVKIIFRVGLVLLK 312
++ +Y ++WF+ F+ P V + D+ CEG+ +IF V L LLK
Sbjct: 713 FLDISLEAHMYASQWFLTLFTAKFPLYMVFHIIDLLLCEGISVIFNVALGLLK 765
>gi|118722351 growth hormone regulated TBC protein 1 [Homo sapiens]
Length = 336
Score = 137 bits (345), Expect = 2e-32
Identities = 89/264 (33%), Positives = 131/264 (49%), Gaps = 8/264 (3%)
Query: 54 RIDKFGFIVGSQGAEGALEEV---PLEVLRQRESKWLDMLNNWDKWMAKKHKKIRLRCQK 110
RID +GF + A E+ L L +R KW +L + + ++ +K
Sbjct: 11 RIDPYGFERPEDFDDAAYEKFFSSYLVTLTRRAIKWSRLLQGGG---VPRSRTVKRYVRK 67
Query: 111 GIPPSLRGRAWQYLSGGKVKLQQNPGKFDELDMSPGDPKWLDVIERDLHRQFPFHEMFVS 170
G+P R R W LSG + ++ QNPG + +L +P+ D I DL+R FP + F
Sbjct: 68 GVPLEHRARVWMVLSGAQAQMDQNPGYYHQLLQGERNPRLEDAIRTDLNRTFPDNVKFRK 127
Query: 171 RGGHG-QQDLFRVLKAYTLYRPEEGYCQAQAPIAAVL-LMHMPAEQAFWCLVQICEKYLP 228
Q+ L+ VL AY + GYCQ IA L L+ E++FW L + + LP
Sbjct: 128 TTDPCLQRTLYNVLLAYGHHNQGVGYCQGMNFIAGYLILITNNEEESFWLLDALVGRILP 187
Query: 229 GYYSEKLEAIQLDGEILFSLLQKVSPVAHKHLSRQKIDPLLYMTEWFMCAFSRTLPWSSV 288
YYS + ++ D E+L L++ P + R + L ++ WF+C F LP +V
Sbjct: 188 DYYSPAMLGLKTDQEVLGELVRAKLPAVGALMERLGVLWTLLVSRWFICLFVDILPVETV 247
Query: 289 LRVWDMFFCEGVKIIFRVGLVLLK 312
LR+WD F EG KIIFRV L L+K
Sbjct: 248 LRIWDCLFNEGSKIIFRVALTLIK 271
>gi|7661864 USP6 N-terminal like isoform 1 [Homo sapiens]
Length = 828
Score = 136 bits (342), Expect = 5e-32
Identities = 122/427 (28%), Positives = 194/427 (45%), Gaps = 31/427 (7%)
Query: 56 DKFGFIVGSQGAEGALEEVPLEVLRQ------RESKWLDMLNNWDKWMAKKHKKIRLRCQ 109
D+FGF+ E L + + V RQ R +KWL ML W+K+ K +K R
Sbjct: 46 DRFGFL-----HEEELPDHNVAVERQKHLEIERTTKWLKMLKGWEKY--KNTEKFHRRIY 98
Query: 110 KGIPPSLRGRAWQYLSGGKVKLQQNPGKFDELD-MSPGDPKWLDVIERDLHRQFPFHEMF 168
KGIP LRG W L ++ + +L + G + I+ D++R F H MF
Sbjct: 99 KGIPLQLRGEVWALLLEIPKMKEETRDLYSKLKHRARGCSPDIRQIDLDVNRTFRDHIMF 158
Query: 169 VSRGGHGQQDLFRVLKAYTLYRPEEGYCQAQAPIAAVLLMHMPAEQAFWCLVQIC---EK 225
R G QQ LF VL AY++Y E GYCQ + I A+LLM+M E AFW LV++ +
Sbjct: 159 RDRYGVKQQSLFHVLAAYSIYNTEVGYCQGMSQITALLLMYMNEEDAFWALVKLFSGPKH 218
Query: 226 YLPGYYSEKLEAIQLDGEILFSLLQKVSPVAHKHLSRQKIDPLLYMTEWFMCAFSRTLPW 285
+ G++ + + E +L K +HL Q+I Y +WF F P+
Sbjct: 219 AMHGFFVQGFPKLLRFQEHHEKILNKFLSKLKQHLDSQEIYTSFYTMKWFFQCFLDRTPF 278
Query: 286 SSVLRVWDMFFCEGVKIIFRVGLVLLKHALGSPEKVKACQGQYETIERLR-SLSPKIMQE 344
+ LR+WD++ EG +++ + +LK L +K E +E + +L+ E
Sbjct: 279 TLNLRIWDIYIFEGERVLTAMSYTILK--LHKKHLMKL--SMEELVEFFQETLAKDFFFE 334
Query: 345 AFLVQEVVELPVTERQIEREHLIQLRRWQETRGELQCRSPPRLHGAKAILDAEPGPRPAL 404
V E +++ +TE + + L + + E + + PP L + + G R
Sbjct: 335 DDFVIEQLQISMTELKRAKLDLPEPGKEDEYPKKPLGQLPPELQ-SWGVHHLSNGQRSVG 393
Query: 405 QPSP--SIRLPLDAPLPGSKAKPKP------PKQAQKEQRKQMKGRGQLEKPPAPNQAMV 456
+PSP S R AP + P P P++AQ +RK ++ + K A Q +
Sbjct: 394 RPSPLASGRRESGAPHRRHEHSPHPQSRTGTPERAQPPRRKSVEEESKKLKDEADFQRKL 453
Query: 457 VAAAGDA 463
+ D+
Sbjct: 454 PSGPQDS 460
>gi|122937432 USP6 N-terminal like isoform 2 [Homo sapiens]
Length = 845
Score = 136 bits (342), Expect = 5e-32
Identities = 122/427 (28%), Positives = 194/427 (45%), Gaps = 31/427 (7%)
Query: 56 DKFGFIVGSQGAEGALEEVPLEVLRQ------RESKWLDMLNNWDKWMAKKHKKIRLRCQ 109
D+FGF+ E L + + V RQ R +KWL ML W+K+ K +K R
Sbjct: 63 DRFGFL-----HEEELPDHNVAVERQKHLEIERTTKWLKMLKGWEKY--KNTEKFHRRIY 115
Query: 110 KGIPPSLRGRAWQYLSGGKVKLQQNPGKFDELD-MSPGDPKWLDVIERDLHRQFPFHEMF 168
KGIP LRG W L ++ + +L + G + I+ D++R F H MF
Sbjct: 116 KGIPLQLRGEVWALLLEIPKMKEETRDLYSKLKHRARGCSPDIRQIDLDVNRTFRDHIMF 175
Query: 169 VSRGGHGQQDLFRVLKAYTLYRPEEGYCQAQAPIAAVLLMHMPAEQAFWCLVQIC---EK 225
R G QQ LF VL AY++Y E GYCQ + I A+LLM+M E AFW LV++ +
Sbjct: 176 RDRYGVKQQSLFHVLAAYSIYNTEVGYCQGMSQITALLLMYMNEEDAFWALVKLFSGPKH 235
Query: 226 YLPGYYSEKLEAIQLDGEILFSLLQKVSPVAHKHLSRQKIDPLLYMTEWFMCAFSRTLPW 285
+ G++ + + E +L K +HL Q+I Y +WF F P+
Sbjct: 236 AMHGFFVQGFPKLLRFQEHHEKILNKFLSKLKQHLDSQEIYTSFYTMKWFFQCFLDRTPF 295
Query: 286 SSVLRVWDMFFCEGVKIIFRVGLVLLKHALGSPEKVKACQGQYETIERLR-SLSPKIMQE 344
+ LR+WD++ EG +++ + +LK L +K E +E + +L+ E
Sbjct: 296 TLNLRIWDIYIFEGERVLTAMSYTILK--LHKKHLMKL--SMEELVEFFQETLAKDFFFE 351
Query: 345 AFLVQEVVELPVTERQIEREHLIQLRRWQETRGELQCRSPPRLHGAKAILDAEPGPRPAL 404
V E +++ +TE + + L + + E + + PP L + + G R
Sbjct: 352 DDFVIEQLQISMTELKRAKLDLPEPGKEDEYPKKPLGQLPPELQ-SWGVHHLSNGQRSVG 410
Query: 405 QPSP--SIRLPLDAPLPGSKAKPKP------PKQAQKEQRKQMKGRGQLEKPPAPNQAMV 456
+PSP S R AP + P P P++AQ +RK ++ + K A Q +
Sbjct: 411 RPSPLASGRRESGAPHRRHEHSPHPQSRTGTPERAQPPRRKSVEEESKKLKDEADFQRKL 470
Query: 457 VAAAGDA 463
+ D+
Sbjct: 471 PSGPQDS 477
>gi|229577000 ecotropic viral integration site 5-like isoform 1
[Homo sapiens]
Length = 805
Score = 135 bits (341), Expect = 7e-32
Identities = 96/305 (31%), Positives = 142/305 (46%), Gaps = 14/305 (4%)
Query: 17 ESLSGTRESLAQGPDAATTDELSSLGSDSEANGFAERRIDKFGFIVGSQGAEGAL----E 72
E+LS S + + DEL L E N E + GS+ G+
Sbjct: 14 EALSAPTCSPTSDSENLSPDELELLAKLEEQNRLLEADSKSMRSMNGSRRNSGSSLVSSS 73
Query: 73 EVPLEVLRQRESKWL---DMLNNWDKWMAKKHKKIRLRCQKGIPPSLRGRAWQYLSGGKV 129
+ E W+ + N W++W +K K ++ +KGIP R WQ L
Sbjct: 74 SASSNLSHLEEDTWILWGRIANEWEEWRRRKEKLLKELIRKGIPHHFRAIVWQLLCSATD 133
Query: 130 KLQQNPGKFDEL-DMSPGDPKWLDVIERDLHRQFPFHEMFVSRGGHGQQDLFRVLKAYTL 188
+N ++ EL MS K +I RD+ R +P HE F + GQ+ LF V+KAY+L
Sbjct: 134 MPVKN--QYSELLKMSSPCEK---LIRRDIARTYPEHEFFKGQDSLGQEVLFNVMKAYSL 188
Query: 189 YRPEEGYCQAQAPIAAVLLMHMPAEQAFWCLVQICEKY-LPGYYSEKLEAIQLDGEILFS 247
E GYCQ A I +LLM MP E+AF V++ ++Y L + + + L
Sbjct: 189 VDREVGYCQGSAFIVGLLLMQMPEEEAFCVFVRLMQEYRLRELFKPSMAELGLCIYQFEY 248
Query: 248 LLQKVSPVAHKHLSRQKIDPLLYMTEWFMCAFSRTLPWSSVLRVWDMFFCEGVKIIFRVG 307
+LQ+ P + H Q +Y + WF+ F T P RV+D+F EG++I+FRVG
Sbjct: 249 MLQEQLPDLNTHFRSQSFHTSMYASSWFLTLFLTTFPLPVATRVFDIFMYEGLEIVFRVG 308
Query: 308 LVLLK 312
L LL+
Sbjct: 309 LALLQ 313
>gi|21687020 ecotropic viral integration site 5-like isoform 2 [Homo
sapiens]
Length = 794
Score = 135 bits (341), Expect = 7e-32
Identities = 96/305 (31%), Positives = 142/305 (46%), Gaps = 14/305 (4%)
Query: 17 ESLSGTRESLAQGPDAATTDELSSLGSDSEANGFAERRIDKFGFIVGSQGAEGAL----E 72
E+LS S + + DEL L E N E + GS+ G+
Sbjct: 14 EALSAPTCSPTSDSENLSPDELELLAKLEEQNRLLEADSKSMRSMNGSRRNSGSSLVSSS 73
Query: 73 EVPLEVLRQRESKWL---DMLNNWDKWMAKKHKKIRLRCQKGIPPSLRGRAWQYLSGGKV 129
+ E W+ + N W++W +K K ++ +KGIP R WQ L
Sbjct: 74 SASSNLSHLEEDTWILWGRIANEWEEWRRRKEKLLKELIRKGIPHHFRAIVWQLLCSATD 133
Query: 130 KLQQNPGKFDEL-DMSPGDPKWLDVIERDLHRQFPFHEMFVSRGGHGQQDLFRVLKAYTL 188
+N ++ EL MS K +I RD+ R +P HE F + GQ+ LF V+KAY+L
Sbjct: 134 MPVKN--QYSELLKMSSPCEK---LIRRDIARTYPEHEFFKGQDSLGQEVLFNVMKAYSL 188
Query: 189 YRPEEGYCQAQAPIAAVLLMHMPAEQAFWCLVQICEKY-LPGYYSEKLEAIQLDGEILFS 247
E GYCQ A I +LLM MP E+AF V++ ++Y L + + + L
Sbjct: 189 VDREVGYCQGSAFIVGLLLMQMPEEEAFCVFVRLMQEYRLRELFKPSMAELGLCIYQFEY 248
Query: 248 LLQKVSPVAHKHLSRQKIDPLLYMTEWFMCAFSRTLPWSSVLRVWDMFFCEGVKIIFRVG 307
+LQ+ P + H Q +Y + WF+ F T P RV+D+F EG++I+FRVG
Sbjct: 249 MLQEQLPDLNTHFRSQSFHTSMYASSWFLTLFLTTFPLPVATRVFDIFMYEGLEIVFRVG 308
Query: 308 LVLLK 312
L LL+
Sbjct: 309 LALLQ 313
>gi|68299759 ecotropic viral integration site 5 [Homo sapiens]
Length = 810
Score = 129 bits (325), Expect = 5e-30
Identities = 86/291 (29%), Positives = 129/291 (44%), Gaps = 12/291 (4%)
Query: 30 PDAATTDELSSLGSDSEANGFAERRIDKFGFIVGSQGAEGAL----EEVPLEVLRQRESK 85
P + D+L L E N E + GS+ G+ + E
Sbjct: 75 PSQLSPDDLELLAKLEEQNRLLETDSKSLRSVNGSRRNSGSSLVSSSSASSNLSHLEEDS 134
Query: 86 WL---DMLNNWDKWMAKKHKKIRLRCQKGIPPSLRGRAWQYLSGGKVKLQQNPGKFDELD 142
W+ ++N W+ KK K+++ KGIP R WQ L Q P K +
Sbjct: 135 WILWGRIVNEWEDVRKKKEKQVKELVHKGIPHHFRAIVWQLLCSA----QSMPIKDQYSE 190
Query: 143 MSPGDPKWLDVIERDLHRQFPFHEMFVSRGGHGQQDLFRVLKAYTLYRPEEGYCQAQAPI 202
+ +I RD+ R +P H F + GQ+ LF V+KAY+L E GYCQ A I
Sbjct: 191 LLKMTSPCEKLIRRDIARTYPEHNFFKEKDSLGQEVLFNVMKAYSLVDREVGYCQGSAFI 250
Query: 203 AAVLLMHMPAEQAFWCLVQICEKY-LPGYYSEKLEAIQLDGEILFSLLQKVSPVAHKHLS 261
+LLM MP E+AF V++ + Y L + + + L ++Q+ P H
Sbjct: 251 VGLLLMQMPEEEAFCVFVKLMQDYRLRELFKPSMAELGLCMYQFECMIQEHLPELFVHFQ 310
Query: 262 RQKIDPLLYMTEWFMCAFSRTLPWSSVLRVWDMFFCEGVKIIFRVGLVLLK 312
Q +Y + WF+ F T P R++D+F EG++I+FRVGL LL+
Sbjct: 311 SQSFHTSMYASSWFLTIFLTTFPLPIATRIFDIFMSEGLEIVFRVGLALLQ 361
>gi|156231067 TBC1 domain family, member 8 [Homo sapiens]
Length = 1140
Score = 128 bits (321), Expect = 1e-29
Identities = 83/254 (32%), Positives = 131/254 (51%), Gaps = 13/254 (5%)
Query: 63 GSQGAEGALEEVPLEVLRQRESKWLDMLNNWDKWMAK-KHKKIRLRCQKGIPPSLRGRAW 121
GSQ + + +++ S W D + + + + +KIR GIP SLRGR W
Sbjct: 461 GSQSPDSRMSREQIKI-----SLWNDHFVEYGRTVCMFRTEKIRKLVAMGIPESLRGRLW 515
Query: 122 QYLSGGKVKLQQNPGKFDEL-DMSPGDPKWL-DVIERDLHRQFPFHEMFVSRGGHGQQDL 179
S L +PG + L + S G + + IERDLHR P H F + G L
Sbjct: 516 LLFSDAVTDLASHPGYYGNLVEESLGKCCLVTEEIERDLHRSLPEHPAFQNETGIAA--L 573
Query: 180 FRVLKAYTLYRPEEGYCQAQAPIAAVLLMHMPAEQAFWCLVQICEKYLPGYYSEKLEAIQ 239
RVL AY P+ GYCQ+ + +VLL++ E+AFW LV +CE+ LP Y++ ++ Q
Sbjct: 574 RRVLTAYAHRNPKIGYCQSMNILTSVLLLYTKEEEAFWLLVAVCERMLPDYFNHRVIGAQ 633
Query: 240 LDGEILFSLLQKVSPVAHKHLSRQKIDPLLYMT-EWFMCAFSRTLPWSSVLRVWDMFFCE 298
+D + L++ P +H++ + L ++ WF+ F +P S + V D FF +
Sbjct: 634 VDQSVFEELIKGHLPELAEHMN--DLSALASVSLSWFLTLFLSIMPLESAVNVVDCFFYD 691
Query: 299 GVKIIFRVGLVLLK 312
G+K IF++GL +L+
Sbjct: 692 GIKAIFQLGLAVLE 705
>gi|45597177 TBC1 domain family, member 9B (with GRAM domain)
isoform b [Homo sapiens]
Length = 1233
Score = 127 bits (318), Expect = 3e-29
Identities = 92/286 (32%), Positives = 143/286 (50%), Gaps = 20/286 (6%)
Query: 66 GAEGALEEVPLEVLRQRESKWLDMLNNWDKWMAK-KHKKIRLRCQKGIPPSLRGRAWQYL 124
GA+GA E++ +E W + + + + K R KGIP SLRG W
Sbjct: 469 GAKGAKEKM-------KEESWHIHFFEYGRGVCMYRTAKTRALVLKGIPESLRGELWLLF 521
Query: 125 SGGKVKLQQNPGKFDEL-DMSPGDPKWL-DVIERDLHRQFPFHEMFVSRGGHGQQDLFRV 182
SG ++ +PG + EL + S G + IERDLHR P H F + G L RV
Sbjct: 522 SGAWNEMVTHPGYYAELVEKSTGKYSLATEEIERDLHRSMPEHPAFQNELGIAA--LRRV 579
Query: 183 LKAYTLYRPEEGYCQAQAPIAAVLLMHMPAEQAFWCLVQICEKYLPGYYSEKLEAIQLDG 242
L AY P GYCQA + +VLL++ E+AFW LV +CE+ LP YY+ ++ +D
Sbjct: 580 LTAYAFRNPTIGYCQAMNIVTSVLLLYGSEEEAFWLLVALCERMLPDYYNTRVVGALVDQ 639
Query: 243 EILFSLLQKVSPVAHKHLSRQKIDPLLYMTEWFMCAFSRTLPWSSVLRVWDMFFCEGVKI 302
I L + P + + + + ++ WF+ F +P+ S + + D FF EG+K+
Sbjct: 640 GIFEELTRDFLPQLSEKMQDLGVISSISLS-WFLTLFLSVMPFESAVVIVDCFFYEGIKV 698
Query: 303 IFRVGLVLL----KHALGSPEKVKACQ--GQY-ETIERLRSLSPKI 341
I +V L +L + LG ++ +A G+Y + + +S+SP I
Sbjct: 699 ILQVALAVLDANMEQLLGCSDEGEAMTMLGRYLDNVVNKQSVSPPI 744
>gi|45597175 TBC1 domain family, member 9B (with GRAM domain)
isoform a [Homo sapiens]
Length = 1250
Score = 127 bits (318), Expect = 3e-29
Identities = 92/286 (32%), Positives = 143/286 (50%), Gaps = 20/286 (6%)
Query: 66 GAEGALEEVPLEVLRQRESKWLDMLNNWDKWMAK-KHKKIRLRCQKGIPPSLRGRAWQYL 124
GA+GA E++ +E W + + + + K R KGIP SLRG W
Sbjct: 469 GAKGAKEKM-------KEESWHIHFFEYGRGVCMYRTAKTRALVLKGIPESLRGELWLLF 521
Query: 125 SGGKVKLQQNPGKFDEL-DMSPGDPKWL-DVIERDLHRQFPFHEMFVSRGGHGQQDLFRV 182
SG ++ +PG + EL + S G + IERDLHR P H F + G L RV
Sbjct: 522 SGAWNEMVTHPGYYAELVEKSTGKYSLATEEIERDLHRSMPEHPAFQNELGIAA--LRRV 579
Query: 183 LKAYTLYRPEEGYCQAQAPIAAVLLMHMPAEQAFWCLVQICEKYLPGYYSEKLEAIQLDG 242
L AY P GYCQA + +VLL++ E+AFW LV +CE+ LP YY+ ++ +D
Sbjct: 580 LTAYAFRNPTIGYCQAMNIVTSVLLLYGSEEEAFWLLVALCERMLPDYYNTRVVGALVDQ 639
Query: 243 EILFSLLQKVSPVAHKHLSRQKIDPLLYMTEWFMCAFSRTLPWSSVLRVWDMFFCEGVKI 302
I L + P + + + + ++ WF+ F +P+ S + + D FF EG+K+
Sbjct: 640 GIFEELTRDFLPQLSEKMQDLGVISSISLS-WFLTLFLSVMPFESAVVIVDCFFYEGIKV 698
Query: 303 IFRVGLVLL----KHALGSPEKVKACQ--GQY-ETIERLRSLSPKI 341
I +V L +L + LG ++ +A G+Y + + +S+SP I
Sbjct: 699 ILQVALAVLDANMEQLLGCSDEGEAMTMLGRYLDNVVNKQSVSPPI 744
>gi|38570101 TBC1 domain family, member 8B (with GRAM domain)
isoform a [Homo sapiens]
Length = 1120
Score = 127 bits (318), Expect = 3e-29
Identities = 81/258 (31%), Positives = 129/258 (50%), Gaps = 9/258 (3%)
Query: 80 RQRESKWLDMLNNWDKWMAK-KHKKIRLRCQKGIPPSLRGRAWQYLSGGKVKLQQNPGKF 138
+ +E W + + ++ + KK R +GIP +LRG W SG + NP +
Sbjct: 455 KMKEQSWKILFAECGRGVSMFRTKKTRDLVVRGIPETLRGELWMLFSGAVNDMATNPDYY 514
Query: 139 DEL-DMSPGDPKWL-DVIERDLHRQFPFHEMFVSRGGHGQQDLFRVLKAYTLYRPEEGYC 196
E+ + S G + IERDL R P H F S G L RVL AY P+ GYC
Sbjct: 515 TEVVEQSLGTCNLATEEIERDLRRSLPEHPAFQSDTGISA--LRRVLTAYAYRNPKIGYC 572
Query: 197 QAQAPIAAVLLMHMPAEQAFWCLVQICEKYLPGYYSEKLEAIQLDGEILFSLLQKVSPVA 256
QA + +VLL++ E+AFW LV +CE+ LP Y++ ++ +D + L++ P
Sbjct: 573 QAMNILTSVLLLYAKEEEAFWLLVAVCERMLPDYFNRRIIGALVDQAVFEELIRDHLPQL 632
Query: 257 HKHLSRQKIDPLLYMTEWFMCAFSRTLPWSSVLRVWDMFFCEGVKIIFRVGLVLLKHALG 316
+H++ + ++ WF+ F LP S + V D FF +G+K I ++GL +L + L
Sbjct: 633 TEHMTDMTFFSSVSLS-WFLTLFISVLPIESAVNVVDCFFYDGIKAILQLGLAILDYNL- 690
Query: 317 SPEKVKACQGQYETIERL 334
+K+ C+ E + L
Sbjct: 691 --DKLLTCKDDAEAVTAL 706
>gi|29648315 small G protein signaling modulator 3 [Homo sapiens]
Length = 749
Score = 126 bits (316), Expect = 5e-29
Identities = 87/275 (31%), Positives = 131/275 (47%), Gaps = 19/275 (6%)
Query: 56 DKFGFIV----GSQGAEGALEEVPLEVLRQRESKW---LDMLNN-------WDKWMAK-- 99
D+FGF V G + L PL + +W L+ +N WDK
Sbjct: 43 DEFGFRVYKEEGDEPGSSLLANSPLMEDAPQRLRWQAHLEFTHNHDVGDLTWDKIAVSLP 102
Query: 100 KHKKIRLRCQKGIPPSLRGRAWQYLSGGKVKLQQNPGKFDELDMSPGDPKWLDV--IERD 157
+ +K+R GIP +R + W LSG K + + + E+ + + + + IE+D
Sbjct: 103 RSEKLRSLVLAGIPHGMRPQLWMRLSGALQKKRNSELSYREIVKNSSNDETIAAKQIEKD 162
Query: 158 LHRQFPFHEMFVSRGGHGQQDLFRVLKAYTLYRPEEGYCQAQAPIAAVLLMHMPAEQAFW 217
L R P + F S G G L RVL+A PE GYCQ +AA LL+ + E AFW
Sbjct: 163 LLRTMPSNACFASMGSIGVPRLRRVLRALAWLYPEIGYCQGTGMVAACLLLFLEEEDAFW 222
Query: 218 CLVQICEKYLP-GYYSEKLEAIQLDGEILFSLLQKVSPVAHKHLSRQKIDPLLYMTEWFM 276
+ I E LP Y+S L +Q D +L L+ + P K L I+ L WF+
Sbjct: 223 MMSAIIEDLLPASYFSTTLLGVQTDQRVLRHLIVQYLPRLDKLLQEHDIELSLITLHWFL 282
Query: 277 CAFSRTLPWSSVLRVWDMFFCEGVKIIFRVGLVLL 311
AF+ + +LR+WD+FF EG +++F++ L +L
Sbjct: 283 TAFASVVDIKLLLRIWDLFFYEGSRVLFQLTLGML 317
>gi|139394668 TBC1 domain family, member 9 (with GRAM domain) [Homo
sapiens]
Length = 1266
Score = 125 bits (314), Expect = 9e-29
Identities = 75/212 (35%), Positives = 113/212 (53%), Gaps = 5/212 (2%)
Query: 102 KKIRLRCQKGIPPSLRGRAWQYLSGGKVKLQQNPGKFDEL-DMSPGDPKWL-DVIERDLH 159
+K R KGIP S+RG W LSG + +PG +++L + S G + IERDLH
Sbjct: 506 EKTRELVLKGIPESMRGELWLLLSGAINEKATHPGYYEDLVEKSMGKYNLATEEIERDLH 565
Query: 160 RQFPFHEMFVSRGGHGQQDLFRVLKAYTLYRPEEGYCQAQAPIAAVLLMHMPAEQAFWCL 219
R P H F + G L RVL AY P GYCQA + +VLL++ E+AFW L
Sbjct: 566 RSLPEHPAFQNEMGIAA--LRRVLTAYAFRNPNIGYCQAMNIVTSVLLLYAKEEEAFWLL 623
Query: 220 VQICEKYLPGYYSEKLEAIQLDGEILFSLLQKVSPVAHKHLSRQKIDPLLYMTEWFMCAF 279
V +CE+ LP YY+ ++ +D + L + P + + + + ++ WF+ F
Sbjct: 624 VALCERMLPDYYNTRVVGALVDQGVFEELARDYVPQLYDCMQDLGVISTISLS-WFLTLF 682
Query: 280 SRTLPWSSVLRVWDMFFCEGVKIIFRVGLVLL 311
+P+ S + V D FF EG+K+IF++ L +L
Sbjct: 683 LSVMPFESAVVVVDCFFYEGIKVIFQLALAVL 714
>gi|194018478 TBC1 domain family, member 2B isoform a [Homo sapiens]
Length = 963
Score = 122 bits (305), Expect = 1e-27
Identities = 107/416 (25%), Positives = 167/416 (40%), Gaps = 57/416 (13%)
Query: 11 RAPAAGESLSGTRESLAQGPDAATTDELSSLGSDSEANGFAERRIDKFGFIVGSQGAEGA 70
+ P E TRE +AQ + A E + D +GF + E
Sbjct: 550 KTPVCSEDQGPTREVIAQLLEDALQVESQEQPEQAFVKPHLVSEYDIYGFRTVPEDDE-- 607
Query: 71 LEEVPLEVLRQRESKWLDMLNN--------WDKWMAKKHKK-------IRLRCQKGIPPS 115
EE + +R + K L + N W+ + A + ++ + GIP
Sbjct: 608 -EEKLVAKVRALDLKTLYLTENQEVSTGVKWENYFASTVNREMMCSPELKNLIRAGIPHE 666
Query: 116 LRGRAWQYLSGG---KVKLQQNPGKFDEL------DMSPGDPKWLDVIERDLHRQFPFHE 166
R + W++ K K PG F L +P + IE DL R P ++
Sbjct: 667 HRSKVWKWCVDRHTRKFKDNTEPGHFQTLLQKALEKQNPASKQ----IELDLLRTLPNNK 722
Query: 167 MFVSRGGHGQQDLFRVLKAYTLYRPEEGYCQAQAPIAAVLLMHMPAEQAFWCLVQICEKY 226
+ G Q L VL A++ P+ GYCQ + AV L+++ E AFWCLV I E +
Sbjct: 723 HYSCPTSEGIQKLRNVLLAFSWRNPDIGYCQGLNRLVAVALLYLEQEDAFWCLVTIVEVF 782
Query: 227 LP-GYYSEKLEAIQLDGEILFSLLQKVSPVAHKHLSRQKIDPLLYMTEWFMCAFSRTLPW 285
+P YY++ L Q+D + L+ + P H H + K+D L WF+ F ++
Sbjct: 783 MPRDYYTKTLLGSQVDQRVFRDLMSEKLPRLHGHFEQYKVDYTLITFNWFLVVFVDSVVS 842
Query: 286 SSVLRVWDMFFCEGVKIIFRVGLVLLKHALGSPEKVKACQGQYETIERLRSLSPKIMQEA 345
+ ++WD F EG K+IFR L L K+ E++ Q + LR + I+
Sbjct: 843 DILFKIWDSFLYEGPKVIFRFALALFKY---KEEEILKLQDSMSIFKYLRYFTRTILDAR 899
Query: 346 FLVQ----------------------EVVELPVTERQIEREHLIQLRRWQETRGEL 379
L+ E V L +TE + RE ++ R +GEL
Sbjct: 900 KLISISFGDLNPFPLRQIRNRRAYHLEKVRLELTELEAIREDFLRERDTSPDKGEL 955
>gi|114688046 TBC1 domain family, member 4 [Homo sapiens]
Length = 1298
Score = 117 bits (294), Expect = 2e-26
Identities = 86/297 (28%), Positives = 137/297 (46%), Gaps = 38/297 (12%)
Query: 88 DMLNNWDKWMAKKHKKIRLRCQ-------KGIPPSLRGRAWQYLSGGKVKLQQNPGKFDE 140
++L WDK + KIR + +G+P S RG WQ+L+ + P K
Sbjct: 888 EVLITWDKKLLNCRAKIRCDMEDIHTLLKEGVPKSRRGEIWQFLALQYRLRHRLPNK--- 944
Query: 141 LDMSPGDPKWLDVIER----------DLHRQFPFHEMFVSRGGHGQQDLFRVLKAYTLYR 190
P D + +++++ DL R FP H F + G GQ LF +LKAY+L
Sbjct: 945 --QQPPDISYKELLKQLTAQQHAILVDLGRTFPTHPYFSVQLGPGQLSLFNLLKAYSLLD 1002
Query: 191 PEEGYCQAQAPIAAVLLMHMPAEQAFWCL------VQICEKYLPGYYSEKLEAIQLDGEI 244
E GYCQ + +A VLL+HM EQAF L + ++Y P S +++ QL
Sbjct: 1003 KEVGYCQGISFVAGVLLLHMSEEQAFEMLKFLMYDLGFRKQYRPDMMSLQIQMYQLS--- 1059
Query: 245 LFSLLQKVSPVAHKHLSRQKIDPLLYMTEWFMCAFSRTLPWSSVLRVWDMFFCEGVKIIF 304
LL + HL +I P LY WF+ F+ V RV+D+ F +G ++IF
Sbjct: 1060 --RLLHDYHRDLYNHLEENEISPSLYAAPWFLTLFASQFSLGFVARVFDIIFLQGTEVIF 1117
Query: 305 RVGLVLLKHALGSPEKVKACQGQYETIERLRSLSPKIMQEAF--LVQEVVELPVTER 359
+V L LL + C+ +E L++ P + ++ +V E+ ++++
Sbjct: 1118 KVALSLLS---SQETLIMECESFENIVEFLKNTLPDMNTSEMEKIITQVFEMDISKQ 1171
>gi|194018476 TBC1 domain family, member 2B isoform b [Homo sapiens]
Length = 914
Score = 117 bits (294), Expect = 2e-26
Identities = 95/357 (26%), Positives = 149/357 (41%), Gaps = 35/357 (9%)
Query: 11 RAPAAGESLSGTRESLAQGPDAATTDELSSLGSDSEANGFAERRIDKFGFIVGSQGAEGA 70
+ P E TRE +AQ + A E + D +GF + E
Sbjct: 550 KTPVCSEDQGPTREVIAQLLEDALQVESQEQPEQAFVKPHLVSEYDIYGFRTVPEDDE-- 607
Query: 71 LEEVPLEVLRQRESKWLDMLNN--------WDKWMAKKHKK-------IRLRCQKGIPPS 115
EE + +R + K L + N W+ + A + ++ + GIP
Sbjct: 608 -EEKLVAKVRALDLKTLYLTENQEVSTGVKWENYFASTVNREMMCSPELKNLIRAGIPHE 666
Query: 116 LRGRAWQYLSGG---KVKLQQNPGKFDEL------DMSPGDPKWLDVIERDLHRQFPFHE 166
R + W++ K K PG F L +P + IE DL R P ++
Sbjct: 667 HRSKVWKWCVDRHTRKFKDNTEPGHFQTLLQKALEKQNPASKQ----IELDLLRTLPNNK 722
Query: 167 MFVSRGGHGQQDLFRVLKAYTLYRPEEGYCQAQAPIAAVLLMHMPAEQAFWCLVQICEKY 226
+ G Q L VL A++ P+ GYCQ + AV L+++ E AFWCLV I E +
Sbjct: 723 HYSCPTSEGIQKLRNVLLAFSWRNPDIGYCQGLNRLVAVALLYLEQEDAFWCLVTIVEVF 782
Query: 227 LP-GYYSEKLEAIQLDGEILFSLLQKVSPVAHKHLSRQKIDPLLYMTEWFMCAFSRTLPW 285
+P YY++ L Q+D + L+ + P H H + K+D L WF+ F ++
Sbjct: 783 MPRDYYTKTLLGSQVDQRVFRDLMSEKLPRLHGHFEQYKVDYTLITFNWFLVVFVDSVVS 842
Query: 286 SSVLRVWDMFFCEGVKIIFRVGLVLLKHALGSPEKVKACQGQYETIERLRSLSPKIM 342
+ ++WD F EG K+IFR L L K+ E++ Q + LR + I+
Sbjct: 843 DILFKIWDSFLYEGPKVIFRFALALFKY---KEEEILKLQDSMSIFKYLRYFTRTIL 896
>gi|50658061 TBC1 (tre-2/USP6, BUB2, cdc16) domain family, member 1
[Homo sapiens]
Length = 1168
Score = 113 bits (282), Expect = 5e-25
Identities = 86/296 (29%), Positives = 141/296 (47%), Gaps = 24/296 (8%)
Query: 79 LRQRESKWLDMLNNWDKWMAK-KHKKIRLRCQKGIPPSLRGRAWQYLSGGKVKLQQNPGK 137
L++ + W ML+ + K +K+ +G+P RG W++L+ Q P K
Sbjct: 767 LKEVTTVWEKMLSTPGRSKIKFDMEKMHSAVGQGVPRHHRGEIWKFLAEQFHLKHQFPSK 826
Query: 138 FDELDMSPGDPKWLDVIER----------DLHRQFPFHEMFVSRGGHGQQDLFRVLKAYT 187
P D + +++++ DL R FP H F ++ G GQ L+ +LKAY+
Sbjct: 827 -----QQPKDVPYKELLKQLTSQQHAILIDLGRTFPTHPYFSAQLGAGQLSLYNILKAYS 881
Query: 188 LYRPEEGYCQAQAPIAAVLLMHMPAEQAFWCL-VQICEKYLPGYYSEKLEAIQLDGEILF 246
L E GYCQ + +A +LL+HM E+AF L + + L Y + +Q+ L
Sbjct: 882 LLDQEVGYCQGLSFVAGILLLHMSEEEAFKMLKFLMFDMGLRKQYRPDMIILQIQMYQLS 941
Query: 247 SLLQKVSPVAHKHLSRQKIDPLLYMTEWFMCAFSRTLPWSSVLRVWDMFFCEGVKIIFRV 306
LL + HL +I P LY WF+ F+ P V RV+DM F +G ++IF+V
Sbjct: 942 RLLHDYHRDLYNHLEEHEIGPSLYAAPWFLTMFASQFPLGFVARVFDMIFLQGTEVIFKV 1001
Query: 307 GLVLLKHALGSPEKVKACQGQYETI-ERLRSLSPK--IMQEAFLVQEVVELPVTER 359
L L LGS + + ETI + ++S P ++Q + +V E+ + ++
Sbjct: 1002 ALSL----LGSHKPLILQHENLETIVDFIKSTLPNLGLVQMEKTINQVFEMDIAKQ 1053
>gi|109638751 ubiquitin specific protease 6 [Homo sapiens]
Length = 1406
Score = 110 bits (274), Expect = 4e-24
Identities = 97/385 (25%), Positives = 169/385 (43%), Gaps = 23/385 (5%)
Query: 55 IDKFGFIVGSQGAEGALEEVPLEVLRQ--RESKWLDMLNNWDKWMAKKHKKIRLRCQKGI 112
ID+FG + ++ E ++ R+ R SKW++ML W+ + K K+ R KGI
Sbjct: 45 IDRFGILHETELPPVTAREAK-KIRREMTRTSKWMEMLGEWETY--KHSSKLIDRVYKGI 101
Query: 113 PPSLRGRAWQYLSGGKVKLQQNPGKFDEL-DMSPGDPKWLDVIERDLHRQFPFHEMFVSR 171
P ++RG W L + +NPG++ + + + + I+ D+ H F R
Sbjct: 102 PMNIRGPVWSVLLNIQEIKLKNPGRYQIMKERGKRSSEHIHHIDLDVRTTLRNHVFFRDR 161
Query: 172 GGHGQQDLFRVLKAYTLYRPEEGYCQAQAPIAAVLLMHMPAEQAFWCLVQI--CEKY-LP 228
G Q++LF +L AY+ Y PE GYC+ + I A+ L+++P E AFW LVQ+ E++ LP
Sbjct: 162 YGAKQRELFYILLAYSEYNPEVGYCRDLSHITALFLLYLPEEDAFWALVQLLASERHSLP 221
Query: 229 GYYSEKLEAIQLDGEILFSLLQKVSPVAHKHLSRQKIDPLLYMTEWFMCAFSRTLPWSSV 288
G++S +Q + ++ K P H ++ + + +
Sbjct: 222 GFHSPNGGTVQGLQDQQEHVVPKSQPKTMWHQDKEGLCGQCASLGCLLRNLIDGISLGLT 281
Query: 289 LRVWDMFFCEGVKIIFRVGLVLLKHALGSPEKVKACQGQYETIERLRSLSPKIMQEAFLV 348
LR+WD++ EG +++ + + LK K C G + + R + M + ++
Sbjct: 282 LRLWDVYLVEGEQVLMPITSIALKVQQKRLMKTSRC-GLWARL-RNQFFDTWAMNDDTVL 339
Query: 349 QEVVELPVTERQIEREHLIQLRRWQETRGELQCRSPPRLHGAKAIL----DAEPGP---- 400
+ L + +++ R+ + +G L R P G K + A PGP
Sbjct: 340 K---HLRASTKKLTRKQGDLPPPAKREQGSLAPRPVPASRGGKTLCKGYRQAPPGPPAQF 396
Query: 401 -RPALQPSPSIRLPLDAPLPGSKAK 424
RP SP P PG +
Sbjct: 397 QRPICSASPPWASRFSTPCPGGAVR 421
>gi|222352143 TBC1 domain family, member 2 [Homo sapiens]
Length = 917
Score = 109 bits (273), Expect = 5e-24
Identities = 93/303 (30%), Positives = 138/303 (45%), Gaps = 18/303 (5%)
Query: 14 AAGESLSGTRESLAQGPDAATTDELSSLGSDS-EANGFAERRIDKFGFI-VGSQGAEGAL 71
A G+ S E L Q A E SDS E + + + D++GF+ V E
Sbjct: 520 ALGDEASECSELLRQLVQEALQWEAGEASSDSIELSPIS--KYDEYGFLTVPDYEVEDLK 577
Query: 72 EEVPLEVLRQRESKWLDM----LNNWDKWMAK----KHKKIRLRCQKGIPPSLRGRAWQY 123
++ L R L + ++W A +++ + G+P R R W++
Sbjct: 578 LLAKIQALESRSHHLLGLEAVDRPLRERWAALGDLVPSAELKQLLRAGVPREHRPRVWRW 637
Query: 124 LSGGKVKLQQNPGKFDELDMSPGDPKWLDV---IERDLHRQFPFHEMFVSRGGHGQQDLF 180
L +V+ PG + EL +S G + IE DL+R FP ++ F L
Sbjct: 638 LVHLRVQHLHTPGCYQEL-LSRGQAREHPAARQIELDLNRTFPNNKHFTCPTSSFPDKLR 696
Query: 181 RVLKAYTLYRPEEGYCQAQAPIAAVLLMHMPAEQ-AFWCLVQICEKYLPG-YYSEKLEAI 238
RVL A++ P GYCQ +AA+ L+ + E+ AFWCLV I E +P YY L A
Sbjct: 697 RVLLAFSWQNPTIGYCQGLNRLAAIALLVLEEEESAFWCLVAIVETIMPADYYCNTLTAS 756
Query: 239 QLDGEILFSLLQKVSPVAHKHLSRQKIDPLLYMTEWFMCAFSRTLPWSSVLRVWDMFFCE 298
Q+D +L LL + P HL + +D L WF+ F+ +L + +LRVWD F E
Sbjct: 757 QVDQRVLQDLLSEKLPRLMAHLGQHHVDLSLVTFNWFLVVFADSLISNILLRVWDAFLYE 816
Query: 299 GVK 301
G K
Sbjct: 817 GTK 819
>gi|226693407 TBC1 domain family, member 3H [Homo sapiens]
Length = 549
Score = 105 bits (263), Expect = 7e-23
Identities = 70/239 (29%), Positives = 120/239 (50%), Gaps = 14/239 (5%)
Query: 82 RESKWLDMLNNWDKWMAKKHKKIRLRCQKGIPPSLRGRAWQYLSGGKVKLQQNPGKFDEL 141
R+SKW+DML +W+K+ K +K+ R KG+P ++RG W L + +NPG++ +
Sbjct: 74 RKSKWVDMLGDWEKY--KSSRKLIDRAYKGMPMNIRGPMWSVLLNIEEMKLKNPGRYQIM 131
Query: 142 -DMSPGDPKWLDVIERDLHRQFPFHEMFVSRGGHGQQDLFRVLKAYTLYRPEEGYCQAQA 200
+ + + I+RD+ H F R G Q++L +L AY Y PE GYC+ +
Sbjct: 132 KEKGKRSSEHIQRIDRDISGTLRKHMFFRDRYGTKQRELLHILLAYEEYNPEVGYCRDLS 191
Query: 201 PIAAVLLMHMPAEQAFWCLVQI--CEKY-LPGYYSEKLEAIQLDGEILFSLLQKVSPVAH 257
IAA+ L+++P E AFW LVQ+ E++ L G++S +Q + ++ P
Sbjct: 192 HIAALFLLYLPEEDAFWALVQLLASERHSLQGFHSPNGGTVQGLQDQQEHVVATSQPKTM 251
Query: 258 KHLSRQKI----DPLLYMTEWFMCAFSRTLPWSSVLRVWDMFFCEGVKIIFRVGLVLLK 312
H ++ + PL + + S L LR+WD++ EG + + + + K
Sbjct: 252 GHQDKKDLCGQCSPLGCLIRILIDGISLGL----TLRLWDVYLVEGEQALMPITRIAFK 306
>gi|14149985 TBC1 domain family, member 3F [Homo sapiens]
Length = 549
Score = 105 bits (263), Expect = 7e-23
Identities = 70/239 (29%), Positives = 120/239 (50%), Gaps = 14/239 (5%)
Query: 82 RESKWLDMLNNWDKWMAKKHKKIRLRCQKGIPPSLRGRAWQYLSGGKVKLQQNPGKFDEL 141
R+SKW+DML +W+K+ K +K+ R KG+P ++RG W L + +NPG++ +
Sbjct: 74 RKSKWVDMLGDWEKY--KSSRKLIDRAYKGMPMNIRGPMWSVLLNTEEMKLKNPGRYQIM 131
Query: 142 -DMSPGDPKWLDVIERDLHRQFPFHEMFVSRGGHGQQDLFRVLKAYTLYRPEEGYCQAQA 200
+ + + I+RD+ H F R G Q++L +L AY Y PE GYC+ +
Sbjct: 132 KEKGKKSSEHIQRIDRDVSGTLRKHIFFRDRYGTKQRELLHILLAYEEYNPEVGYCRDLS 191
Query: 201 PIAAVLLMHMPAEQAFWCLVQI--CEKY-LPGYYSEKLEAIQLDGEILFSLLQKVSPVAH 257
IAA+ L+++P E AFW LVQ+ E++ L G++S +Q + ++ P
Sbjct: 192 HIAALFLLYLPEEDAFWALVQLLASERHSLQGFHSPNGGTVQGLQDQQEHVVATSQPKTM 251
Query: 258 KHLSRQKI----DPLLYMTEWFMCAFSRTLPWSSVLRVWDMFFCEGVKIIFRVGLVLLK 312
H ++ + PL + + S L LR+WD++ EG + + + + K
Sbjct: 252 GHQDKKDLCGQCSPLGCLIRILIDGISLGL----TLRLWDVYLVEGEQALMPITRIAFK 306
>gi|157502205 TBC1 domain family, member 3G [Homo sapiens]
Length = 549
Score = 105 bits (263), Expect = 7e-23
Identities = 70/239 (29%), Positives = 120/239 (50%), Gaps = 14/239 (5%)
Query: 82 RESKWLDMLNNWDKWMAKKHKKIRLRCQKGIPPSLRGRAWQYLSGGKVKLQQNPGKFDEL 141
R+SKW+DML +W+K+ K +K+ R KG+P ++RG W L + +NPG++ +
Sbjct: 74 RKSKWVDMLGDWEKY--KSSRKLIDRAYKGMPMNIRGPMWSVLLNIEEMKLKNPGRYQIM 131
Query: 142 -DMSPGDPKWLDVIERDLHRQFPFHEMFVSRGGHGQQDLFRVLKAYTLYRPEEGYCQAQA 200
+ + + I+RD+ H F R G Q++L +L AY Y PE GYC+ +
Sbjct: 132 KEKGKRSSEHIQRIDRDISGTLRKHMFFRDRYGTKQRELLHILLAYEEYNPEVGYCRDLS 191
Query: 201 PIAAVLLMHMPAEQAFWCLVQI--CEKY-LPGYYSEKLEAIQLDGEILFSLLQKVSPVAH 257
IAA+ L+++P E AFW LVQ+ E++ L G++S +Q + ++ P
Sbjct: 192 HIAALFLLYLPEEDAFWALVQLLASERHSLQGFHSPNGGTVQGLQDQQEHVVATSQPKTM 251
Query: 258 KHLSRQKI----DPLLYMTEWFMCAFSRTLPWSSVLRVWDMFFCEGVKIIFRVGLVLLK 312
H ++ + PL + + S L LR+WD++ EG + + + + K
Sbjct: 252 GHQDKKDLCGQCSPLGCLIRILIDGISLGL----TLRLWDVYLVEGEQALMPITRIAFK 306
>gi|183583565 TBC1 domain family, member 3 [Homo sapiens]
Length = 549
Score = 105 bits (261), Expect = 1e-22
Identities = 70/239 (29%), Positives = 120/239 (50%), Gaps = 14/239 (5%)
Query: 82 RESKWLDMLNNWDKWMAKKHKKIRLRCQKGIPPSLRGRAWQYLSGGKVKLQQNPGKFDEL 141
R+SKW+DML +W+K+ K +K+ R KG+P ++RG W L + +NPG++ +
Sbjct: 74 RKSKWVDMLGDWEKY--KSSRKLIDRAYKGMPMNIRGPMWSVLLNIEEMKLKNPGRYQIM 131
Query: 142 -DMSPGDPKWLDVIERDLHRQFPFHEMFVSRGGHGQQDLFRVLKAYTLYRPEEGYCQAQA 200
+ + + I+RD+ H F R G Q++L +L AY Y PE GYC+ +
Sbjct: 132 KEKGKRSSEHIQRIDRDVSGTLRKHIFFRDRYGTKQRELLHILLAYEEYNPEVGYCRDLS 191
Query: 201 PIAAVLLMHMPAEQAFWCLVQI--CEKY-LPGYYSEKLEAIQLDGEILFSLLQKVSPVAH 257
IAA+ L+++P E AFW LVQ+ E++ L G++S +Q + ++ P
Sbjct: 192 HIAALFLLYLPEEDAFWALVQLLASERHSLQGFHSPNGGTVQGLQDQQEHVVATSQPKTM 251
Query: 258 KHLSRQKI----DPLLYMTEWFMCAFSRTLPWSSVLRVWDMFFCEGVKIIFRVGLVLLK 312
H ++ + PL + + S L LR+WD++ EG + + + + K
Sbjct: 252 GHQDKKDLCGQCSPLGCLIRILIDGISLGL----TLRLWDVYLVEGEQALMPITRIAFK 306
>gi|183583567 TBC1 domain family, member 3E [Homo sapiens]
Length = 549
Score = 105 bits (261), Expect = 1e-22
Identities = 70/239 (29%), Positives = 120/239 (50%), Gaps = 14/239 (5%)
Query: 82 RESKWLDMLNNWDKWMAKKHKKIRLRCQKGIPPSLRGRAWQYLSGGKVKLQQNPGKFDEL 141
R+SKW+DML +W+K+ K +K+ R KG+P ++RG W L + +NPG++ +
Sbjct: 74 RKSKWVDMLGDWEKY--KSSRKLIDRAYKGMPMNIRGPMWSVLLNIEEMKLKNPGRYQIM 131
Query: 142 -DMSPGDPKWLDVIERDLHRQFPFHEMFVSRGGHGQQDLFRVLKAYTLYRPEEGYCQAQA 200
+ + + I+RD+ H F R G Q++L +L AY Y PE GYC+ +
Sbjct: 132 KEKGKRSSEHIQRIDRDVSGTLRKHIFFRDRYGTKQRELLHILLAYEEYNPEVGYCRDLS 191
Query: 201 PIAAVLLMHMPAEQAFWCLVQI--CEKY-LPGYYSEKLEAIQLDGEILFSLLQKVSPVAH 257
IAA+ L+++P E AFW LVQ+ E++ L G++S +Q + ++ P
Sbjct: 192 HIAALFLLYLPEEDAFWALVQLLASERHSLQGFHSPNGGTVQGLQDQQEHVVATSQPKTM 251
Query: 258 KHLSRQKI----DPLLYMTEWFMCAFSRTLPWSSVLRVWDMFFCEGVKIIFRVGLVLLK 312
H ++ + PL + + S L LR+WD++ EG + + + + K
Sbjct: 252 GHQDKKDLCGQCSPLGCLIRILIDGISLGL----TLRLWDVYLVEGEQALMPITRIAFK 306
>gi|183583563 TBC1 domain family, member 3D [Homo sapiens]
Length = 549
Score = 105 bits (261), Expect = 1e-22
Identities = 70/239 (29%), Positives = 120/239 (50%), Gaps = 14/239 (5%)
Query: 82 RESKWLDMLNNWDKWMAKKHKKIRLRCQKGIPPSLRGRAWQYLSGGKVKLQQNPGKFDEL 141
R+SKW+DML +W+K+ K +K+ R KG+P ++RG W L + +NPG++ +
Sbjct: 74 RKSKWVDMLGDWEKY--KSSRKLIDRAYKGMPMNIRGPMWSVLLNIEEMKLKNPGRYQIM 131
Query: 142 -DMSPGDPKWLDVIERDLHRQFPFHEMFVSRGGHGQQDLFRVLKAYTLYRPEEGYCQAQA 200
+ + + I+RD+ H F R G Q++L +L AY Y PE GYC+ +
Sbjct: 132 KEKGKRSSEHIQRIDRDVSGTLRKHIFFRDRYGTKQRELLHILLAYEEYNPEVGYCRDLS 191
Query: 201 PIAAVLLMHMPAEQAFWCLVQI--CEKY-LPGYYSEKLEAIQLDGEILFSLLQKVSPVAH 257
IAA+ L+++P E AFW LVQ+ E++ L G++S +Q + ++ P
Sbjct: 192 HIAALFLLYLPEEDAFWALVQLLASERHSLQGFHSPNGGTVQGLQDQQEHVVATSQPKTM 251
Query: 258 KHLSRQKI----DPLLYMTEWFMCAFSRTLPWSSVLRVWDMFFCEGVKIIFRVGLVLLK 312
H ++ + PL + + S L LR+WD++ EG + + + + K
Sbjct: 252 GHQDKKDLCGQCSPLGCLIRILIDGISLGL----TLRLWDVYLVEGEQALMPITRIAFK 306
>gi|90577185 TBC1 domain family member 3C [Homo sapiens]
Length = 549
Score = 104 bits (259), Expect = 2e-22
Identities = 71/241 (29%), Positives = 120/241 (49%), Gaps = 18/241 (7%)
Query: 82 RESKWLDMLNNWDKWMAKKHKKIRLRCQKGIPPSLRGRAWQYLSGGKVKLQQNPGKFDEL 141
R+SKW+DML +W+K+ K +K+ R KG+P ++RG W L + +NPG++ +
Sbjct: 74 RKSKWVDMLGDWEKY--KSSRKLIDRAYKGMPMNIRGPMWSVLLNIEEMKLKNPGRYQIM 131
Query: 142 -DMSPGDPKWLDVIERDLHRQFPFHEMFVSRGGHGQQDLFRVLKAYTLYRPEEGYCQAQA 200
+ + + I+RD+ H F R G Q++L +L AY Y PE GYC+ +
Sbjct: 132 KEKGKRSSEHIQRIDRDISGTLRKHMFFRDRYGTKQRELLHILLAYEEYNPEVGYCRDLS 191
Query: 201 PIAAVLLMHMPAEQAFWCLVQI--CEKY-LPGYYSEK---LEAIQLDGEILFSLLQKVSP 254
IAA+ L+++P E AFW LVQ+ E++ L G++S ++ +Q E + + Q
Sbjct: 192 HIAALFLLYLPEEDAFWALVQLLASERHSLQGFHSPNGGTVQGLQDQQEHVVATSQS--- 248
Query: 255 VAHKHLSRQKIDPLLYMTEWFMCAFSRTLPWSSV---LRVWDMFFCEGVKIIFRVGLVLL 311
K + Q L C + S+ LR+WD++ EG + + + +
Sbjct: 249 ---KTMGHQDKKDLCGQCSPLGCLIRILIDGISLGLTLRLWDVYLVEGEQALMPITRIAF 305
Query: 312 K 312
K
Sbjct: 306 K 306
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.317 0.134 0.410
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 23,257,114
Number of Sequences: 37866
Number of extensions: 1259205
Number of successful extensions: 7898
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 94
Number of HSP's successfully gapped in prelim test: 385
Number of HSP's that attempted gapping in prelim test: 6742
Number of HSP's gapped (non-prelim): 1323
length of query: 508
length of database: 18,247,518
effective HSP length: 107
effective length of query: 401
effective length of database: 14,195,856
effective search space: 5692538256
effective search space used: 5692538256
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.