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Search of human proteins with 13994190
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|13994190 frizzled 8 [Homo sapiens]
(694 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|13994190 frizzled 8 [Homo sapiens] 1462 0.0
gi|27894385 frizzled 5 precursor [Homo sapiens] 790 0.0
gi|4503827 frizzled 2 [Homo sapiens] 525 e-149
gi|4503825 frizzled 1 [Homo sapiens] 508 e-144
gi|4503833 frizzled 7 [Homo sapiens] 504 e-143
gi|6005762 frizzled 10 [Homo sapiens] 472 e-133
gi|4503835 frizzled 9 [Homo sapiens] 452 e-127
gi|22547161 frizzled 4 [Homo sapiens] 338 8e-93
gi|8393378 frizzled 3 [Homo sapiens] 272 9e-73
gi|34734079 frizzled 6 [Homo sapiens] 262 7e-70
gi|5032099 smoothened [Homo sapiens] 159 8e-39
gi|38455388 frizzled-related protein [Homo sapiens] 132 1e-30
gi|170784838 secreted frizzled-related protein 4 [Homo sapiens] 121 2e-27
gi|48475052 secreted frizzled-related protein 2 precursor [Homo ... 107 3e-23
gi|188528609 secreted frizzled-related protein 5 [Homo sapiens] 103 7e-22
gi|56117838 secreted frizzled-related protein 1 [Homo sapiens] 93 7e-19
gi|29244926 corin [Homo sapiens] 90 8e-18
gi|13899255 membrane frizzled-related protein [Homo sapiens] 69 1e-11
gi|110347449 POU domain, class 4, transcription factor 1 [Homo s... 64 4e-10
gi|62388875 carboxypeptidase Z isoform 2 precursor [Homo sapiens] 61 3e-09
gi|62388877 carboxypeptidase Z isoform 1 [Homo sapiens] 61 4e-09
gi|122937319 even-skipped homeobox 2 [Homo sapiens] 60 9e-09
gi|33620755 YEATS domain containing 2 [Homo sapiens] 57 4e-08
gi|116284398 WAS/WASL interacting protein family, member 1 [Homo... 56 1e-07
gi|38373695 WAS/WASL interacting protein family, member 1 [Homo ... 56 1e-07
gi|4502565 calpain, small subunit 1 [Homo sapiens] 55 2e-07
gi|51599151 calpain, small subunit 1 [Homo sapiens] 55 2e-07
gi|109452587 family with sequence similarity 98, member B isofor... 55 2e-07
gi|5032007 purine-rich element binding protein A [Homo sapiens] 55 2e-07
gi|22547197 zinc finger protein of the cerebellum 2 [Homo sapiens] 55 2e-07
>gi|13994190 frizzled 8 [Homo sapiens]
Length = 694
Score = 1462 bits (3785), Expect = 0.0
Identities = 694/694 (100%), Positives = 694/694 (100%)
Query: 1 MEWGYLLEVTSLLAALALLQRSSGAAAASAKELACQEITVPLCKGIGYNYTYMPNQFNHD 60
MEWGYLLEVTSLLAALALLQRSSGAAAASAKELACQEITVPLCKGIGYNYTYMPNQFNHD
Sbjct: 1 MEWGYLLEVTSLLAALALLQRSSGAAAASAKELACQEITVPLCKGIGYNYTYMPNQFNHD 60
Query: 61 TQDEAGLEVHQFWPLVEIQCSPDLKFFLCSMYTPICLEDYKKPLPPCRSVCERAKAGCAP 120
TQDEAGLEVHQFWPLVEIQCSPDLKFFLCSMYTPICLEDYKKPLPPCRSVCERAKAGCAP
Sbjct: 61 TQDEAGLEVHQFWPLVEIQCSPDLKFFLCSMYTPICLEDYKKPLPPCRSVCERAKAGCAP 120
Query: 121 LMRQYGFAWPDRMRCDRLPEQGNPDTLCMDYNRTDLTTAAPSPPRRLPPPPPGEQPPSGS 180
LMRQYGFAWPDRMRCDRLPEQGNPDTLCMDYNRTDLTTAAPSPPRRLPPPPPGEQPPSGS
Sbjct: 121 LMRQYGFAWPDRMRCDRLPEQGNPDTLCMDYNRTDLTTAAPSPPRRLPPPPPGEQPPSGS 180
Query: 181 GHGRPPGARPPHRGGGRGGGGGDAAAPPARGGGGGGKARPPGGGAAPCEPGCQCRAPMVS 240
GHGRPPGARPPHRGGGRGGGGGDAAAPPARGGGGGGKARPPGGGAAPCEPGCQCRAPMVS
Sbjct: 181 GHGRPPGARPPHRGGGRGGGGGDAAAPPARGGGGGGKARPPGGGAAPCEPGCQCRAPMVS 240
Query: 241 VSSERHPLYNRVKTGQIANCALPCHNPFFSQDERAFTVFWIGLWSVLCFVSTFATVSTFL 300
VSSERHPLYNRVKTGQIANCALPCHNPFFSQDERAFTVFWIGLWSVLCFVSTFATVSTFL
Sbjct: 241 VSSERHPLYNRVKTGQIANCALPCHNPFFSQDERAFTVFWIGLWSVLCFVSTFATVSTFL 300
Query: 301 IDMERFKYPERPIIFLSACYLFVSVGYLVRLVAGHEKVACSGGAPGAGGAGGAGGAAAGA 360
IDMERFKYPERPIIFLSACYLFVSVGYLVRLVAGHEKVACSGGAPGAGGAGGAGGAAAGA
Sbjct: 301 IDMERFKYPERPIIFLSACYLFVSVGYLVRLVAGHEKVACSGGAPGAGGAGGAGGAAAGA 360
Query: 361 GAAGAGAGGPGGRGEYEELGAVEQHVRYETTGPALCTVVFLLVYFFGMASSIWWVILSLT 420
GAAGAGAGGPGGRGEYEELGAVEQHVRYETTGPALCTVVFLLVYFFGMASSIWWVILSLT
Sbjct: 361 GAAGAGAGGPGGRGEYEELGAVEQHVRYETTGPALCTVVFLLVYFFGMASSIWWVILSLT 420
Query: 421 WFLAAGMKWGNEAIAGYSQYFHLAAWLVPSVKSIAVLALSSVDGDPVAGICYVGNQSLDN 480
WFLAAGMKWGNEAIAGYSQYFHLAAWLVPSVKSIAVLALSSVDGDPVAGICYVGNQSLDN
Sbjct: 421 WFLAAGMKWGNEAIAGYSQYFHLAAWLVPSVKSIAVLALSSVDGDPVAGICYVGNQSLDN 480
Query: 481 LRGFVLAPLVIYLFIGTMFLLAGFVSLFRIRSVIKQQDGPTKTHKLEKLMIRLGLFTVLY 540
LRGFVLAPLVIYLFIGTMFLLAGFVSLFRIRSVIKQQDGPTKTHKLEKLMIRLGLFTVLY
Sbjct: 481 LRGFVLAPLVIYLFIGTMFLLAGFVSLFRIRSVIKQQDGPTKTHKLEKLMIRLGLFTVLY 540
Query: 541 TVPAAVVVACLFYEQHNRPRWEATHNCPCLRDLQPDQARRPDYAVFMLKYFMCLVVGITS 600
TVPAAVVVACLFYEQHNRPRWEATHNCPCLRDLQPDQARRPDYAVFMLKYFMCLVVGITS
Sbjct: 541 TVPAAVVVACLFYEQHNRPRWEATHNCPCLRDLQPDQARRPDYAVFMLKYFMCLVVGITS 600
Query: 601 GVWVWSGKTLESWRSLCTRCCWASKGAAVGGGAGATAAGGGGGPGGGGGGGPGGGGGPGG 660
GVWVWSGKTLESWRSLCTRCCWASKGAAVGGGAGATAAGGGGGPGGGGGGGPGGGGGPGG
Sbjct: 601 GVWVWSGKTLESWRSLCTRCCWASKGAAVGGGAGATAAGGGGGPGGGGGGGPGGGGGPGG 660
Query: 661 GGGSLYSDVSTGLTWRSGTASSVSYPKQMPLSQV 694
GGGSLYSDVSTGLTWRSGTASSVSYPKQMPLSQV
Sbjct: 661 GGGSLYSDVSTGLTWRSGTASSVSYPKQMPLSQV 694
>gi|27894385 frizzled 5 precursor [Homo sapiens]
Length = 585
Score = 790 bits (2039), Expect = 0.0
Identities = 413/683 (60%), Positives = 464/683 (67%), Gaps = 115/683 (16%)
Query: 16 LALLQRSSGAAAASAKELACQEITVPLCKGIGYNYTYMPNQFNHDTQDEAGLEVHQFWPL 75
L LL + G AAA++K CQEITVP+C+GIGYN T+MPNQFNHDTQDEAGLEVHQFWPL
Sbjct: 14 LLLLAQLVGRAAAASKAPVCQEITVPMCRGIGYNLTHMPNQFNHDTQDEAGLEVHQFWPL 73
Query: 76 VEIQCSPDLKFFLCSMYTPICLEDYKKPLPPCRSVCERAKAGCAPLMRQYGFAWPDRMRC 135
VEIQCSPDL+FFLCSMYTPICL DY KPLPPCRSVCERAKAGC+PLMRQYGFAWP+RM C
Sbjct: 74 VEIQCSPDLRFFLCSMYTPICLPDYHKPLPPCRSVCERAKAGCSPLMRQYGFAWPERMSC 133
Query: 136 DRLPEQG-NPDTLCMDYNRTDLTTAAPSPPRRLPPPP--PGEQPPSGSGHGRPPGARPPH 192
DRLP G + + LCMDYNR++ TTA PPR P P PG PPGA
Sbjct: 134 DRLPVLGRDAEVLCMDYNRSEATTA---PPRPFPAKPTLPG-----------PPGA---- 175
Query: 193 RGGGRGGGGGDAAAPPARGGGGGGKARPPGGGAAPCEPGCQCRAPMVSVSSERHPLYNRV 252
PA GG P GG C+ CR P V + E HPLYN+V
Sbjct: 176 ---------------PASGG------ECPAGGPFVCK----CREPFVPILKESHPLYNKV 210
Query: 253 KTGQIANCALPCHNPFFSQDERAFTVFWIGLWSVLCFVSTFATVSTFLIDMERFKYPERP 312
+TGQ+ NCA+PC+ P FS DER F FWIGLWSVLCF+ST TV+TFLIDMERF+YPERP
Sbjct: 211 RTGQVPNCAVPCYQPSFSADERTFATFWIGLWSVLCFISTSTTVATFLIDMERFRYPERP 270
Query: 313 IIFLSACYLFVSVGYLVRLVAGHEKVACSGGAPGAGGAGGAGGAAAGAGAAGAGAGGPGG 372
IIFLSACYL VS+G+LVRLV GH VACS
Sbjct: 271 IIFLSACYLCVSLGFLVRLVVGHASVACS------------------------------- 299
Query: 373 RGEYEELGAVEQHVRYETTGPALCTVVFLLVYFFGMASSIWWVILSLTWFLAAGMKWGNE 432
H+ YETTGPALCT+VFLLVYFFGMASSIWWVILSLTWFLAAGMKWGNE
Sbjct: 300 --------REHNHIHYETTGPALCTIVFLLVYFFGMASSIWWVILSLTWFLAAGMKWGNE 351
Query: 433 AIAGYSQYFHLAAWLVPSVKSIAVLALSSVDGDPVAGICYVGNQSLDNLRGFVLAPLVIY 492
AIAGY+QYFHLAAWL+PSVKSI LALSSVDGDPVAGICYVGNQ+L++LRGFVL PLV+Y
Sbjct: 352 AIAGYAQYFHLAAWLIPSVKSITALALSSVDGDPVAGICYVGNQNLNSLRGFVLGPLVLY 411
Query: 493 LFIGTMFLLAGFVSLFRIRSVIKQQDGPTKTHKLEKLMIRLGLFTVLYTVPAAVVVACLF 552
L +GT+FLLAGFVSLFRIRSVIKQ G TKT KLEKLMIR+G+FT+LYTVPA++VVAC
Sbjct: 412 LLVGTLFLLAGFVSLFRIRSVIKQ--GGTKTDKLEKLMIRIGIFTLLYTVPASIVVACYL 469
Query: 553 YEQHNRPRWEATHNCPCLRDLQPDQARRPDYAVFMLKYFMCLVVGITSGVWVWSGKTLES 612
YEQH R WEA C C +P+Y V MLKYFMCLVVGITSGVW+WSGKT+ES
Sbjct: 470 YEQHYRESWEAALTCACPGHDTGQPRAKPEYWVLMLKYFMCLVVGITSGVWIWSGKTVES 529
Query: 613 WRSLCTRCCWASKGAAVGGGAGATAAGGGGGPGGGGGGGPGGGGGPGGGGGSLYSDVSTG 672
WR +RCC + G GA AAG Y + S
Sbjct: 530 WRRFTSRCCCRPRRGHKSG--GAMAAGD-------------------------YPEASAA 562
Query: 673 LTWRSG-TASSVSYPKQMPLSQV 694
LT R+G + +Y KQ+ LS V
Sbjct: 563 LTGRTGPPGPAATYHKQVSLSHV 585
>gi|4503827 frizzled 2 [Homo sapiens]
Length = 565
Score = 525 bits (1352), Expect = e-149
Identities = 293/628 (46%), Positives = 371/628 (59%), Gaps = 103/628 (16%)
Query: 12 LLAALALLQRSSGAAAASAKELA------CQEITVPLCKGIGYNYTYMPNQFNHDTQDEA 65
LL L LL + A K ++ CQ I++PLC I YN T MPN H Q++A
Sbjct: 10 LLLPLLLLPAAGPAQFHGEKGISIPDHGFCQPISIPLCTDIAYNQTIMPNLLGHTNQEDA 69
Query: 66 GLEVHQFWPLVEIQCSPDLKFFLCSMYTPICLEDYKKPLPPCRSVCERAKAGCAPLMRQY 125
GLEVHQF+PLV++QCSP+L+FFLCSMY P+C ++ +PPCRS+CERA+ GC LM ++
Sbjct: 70 GLEVHQFYPLVKVQCSPELRFFLCSMYAPVCTV-LEQAIPPCRSICERARQGCEALMNKF 128
Query: 126 GFAWPDRMRCDRLPEQGNPDTLCMDYNRTDLTTAAPSPPRRLPPPPPGEQPPSGSGHGRP 185
GF WP+R+RC+ P G + +C+ N ++ AP+ PPP G
Sbjct: 129 GFQWPERLRCEHFPRHG-AEQICVGQNHSE--DGAPALLTTAPPP------------GLQ 173
Query: 186 PGARPPHRGGGRGGGGGDAAAPPARGGGGGGKARPPGGGAAPCEPGCQCRAPMVSVSSER 245
PGA GG GG G APP A E C + +
Sbjct: 174 PGA------GGTPGGPGGGGAPPRY---------------ATLEHPFHCPRVL------K 206
Query: 246 HPLYNRVKTGQIANCALPCH------NPFFSQDERAFTVFWIGLWSVLCFVSTFATVSTF 299
P Y K +CA PC + FFSQ+E F WI WSVLC STF TV+T+
Sbjct: 207 VPSYLSYKFLGERDCAAPCEPARPDGSMFFSQEETRFARLWILTWSVLCCASTFFTVTTY 266
Query: 300 LIDMERFKYPERPIIFLSACYLFVSVGYLVRLVAGHEKVACSGGAPGAGGAGGAGGAAAG 359
L+DM+RF+YPERPIIFLS CY VSV Y+ V E+V C+
Sbjct: 267 LVDMQRFRYPERPIIFLSGCYTMVSVAYIAGFVL-QERVVCNE----------------- 308
Query: 360 AGAAGAGAGGPGGRGEYEELGAVEQHVRYETTGPALCTVVFLLVYFFGMASSIWWVILSL 419
R + V Q + E CT++F+++YFF MASSIWWVILSL
Sbjct: 309 -------------RFSEDGYRTVVQGTKKEG-----CTILFMMLYFFSMASSIWWVILSL 350
Query: 420 TWFLAAGMKWGNEAIAGYSQYFHLAAWLVPSVKSIAVLALSSVDGDPVAGICYVGNQSLD 479
TWFLAAGMKWG+EAI SQYFHLAAW VP+VK+I +LA+ +DGD ++G+C+VG SLD
Sbjct: 351 TWFLAAGMKWGHEAIEANSQYFHLAAWAVPAVKTITILAMGQIDGDLLSGVCFVGLNSLD 410
Query: 480 NLRGFVLAPLVIYLFIGTMFLLAGFVSLFRIRSVIKQQDGPTKTHKLEKLMIRLGLFTVL 539
LRGFVLAPL +YLFIGT FLLAGFVSLFRIR+++K DG TKT KLE+LM+R+G+F+VL
Sbjct: 411 PLRGFVLAPLFVYLFIGTSFLLAGFVSLFRIRTIMK-HDG-TKTEKLERLMVRIGVFSVL 468
Query: 540 YTVPAAVVVACLFYEQHNRPRWE---ATHNC-----PCLRDLQPDQARRPDYAVFMLKYF 591
YTVPA +V+AC FYEQ R WE + +C PC P + PD+ V+M+KY
Sbjct: 469 YTVPATIVIACYFYEQAFREHWERSWVSQHCKSLAIPCPAHYTPRMS--PDFTVYMIKYL 526
Query: 592 MCLVVGITSGVWVWSGKTLESWRSLCTR 619
M L+VGITSG W+WSGKTL SWR TR
Sbjct: 527 MTLIVGITSGFWIWSGKTLHSWRKFYTR 554
Score = 29.6 bits (65), Expect = 9.8
Identities = 15/24 (62%), Positives = 15/24 (62%), Gaps = 1/24 (4%)
Query: 636 TAAGGGGGPGGGGG-GGPGGGGGP 658
TA G PG GG GGPGGGG P
Sbjct: 166 TAPPPGLQPGAGGTPGGPGGGGAP 189
>gi|4503825 frizzled 1 [Homo sapiens]
Length = 647
Score = 508 bits (1308), Expect = e-144
Identities = 284/611 (46%), Positives = 355/611 (58%), Gaps = 102/611 (16%)
Query: 35 CQEITVPLCKGIGYNYTYMPNQFNHDTQDEAGLEVHQFWPLVEIQCSPDLKFFLCSMYTP 94
CQ I++PLC I YN T MPN H Q++AGLEVHQF+PLV++QCS +LKFFLCSMY P
Sbjct: 116 CQPISIPLCTDIAYNQTIMPNLLGHTNQEDAGLEVHQFYPLVKVQCSAELKFFLCSMYAP 175
Query: 95 ICLEDYKKPLPPCRSVCERAKAGCAPLMRQYGFAWPDRMRCDRLPEQGNPDTLCMDYNRT 154
+C ++ LPPCRS+CERA+ GC LM ++GF WPD ++C++ P G + LC+ N +
Sbjct: 176 VCTV-LEQALPPCRSLCERARQGCEALMNKFGFQWPDTLKCEKFPVHGAGE-LCVGQNTS 233
Query: 155 DLTTAAPSPPRRLPPPPPGEQPPSGSGHGRPPGARPPHRGGGRGGGGGDAAAPPARGGGG 214
D T PS L P P G G HRGG GG G
Sbjct: 234 DKGTPTPS----LLPEFWTSNPQHGGGG---------HRGGFPGGAGASER--------- 271
Query: 215 GGKARPPGGGAAPCEPGCQCRAPMVSVSSERHPLYNRVKTGQIANCALPCHNP------F 268
GK P RA V H L + +C PC +
Sbjct: 272 -GKFSCP-------------RALKVPSYLNYHFLGEK-------DCGAPCEPTKVYGLMY 310
Query: 269 FSQDERAFTVFWIGLWSVLCFVSTFATVSTFLIDMERFKYPERPIIFLSACYLFVSVGYL 328
F +E F+ WIG+WSVLC ST TV T+L+DM RF YPERPIIFLS CY V+V Y+
Sbjct: 311 FGPEELRFSRTWIGIWSVLCCASTLFTVLTYLVDMRRFSYPERPIIFLSGCYTAVAVAYI 370
Query: 329 VRLVAGHEKVACSGGAPGAGGAGGAGGAAAGAGAAGAGAGGPGGRGEYEELGAVEQHVRY 388
+ ++V C+ A GA G G
Sbjct: 371 AGFLL-EDRVVCNDKF-----------AEDGARTVAQGTKKEG----------------- 401
Query: 389 ETTGPALCTVVFLLVYFFGMASSIWWVILSLTWFLAAGMKWGNEAIAGYSQYFHLAAWLV 448
CT++F+++YFF MASSIWWVILSLTWFLAAGMKWG+EAI SQYFHLAAW V
Sbjct: 402 -------CTILFMMLYFFSMASSIWWVILSLTWFLAAGMKWGHEAIEANSQYFHLAAWAV 454
Query: 449 PSVKSIAVLALSSVDGDPVAGICYVGNQSLDNLRGFVLAPLVIYLFIGTMFLLAGFVSLF 508
P++K+I +LAL VDGD ++G+C+VG ++D LRGFVLAPL +YLFIGT FLLAGFVSLF
Sbjct: 455 PAIKTITILALGQVDGDVLSGVCFVGLNNVDALRGFVLAPLFVYLFIGTSFLLAGFVSLF 514
Query: 509 RIRSVIKQQDGPTKTHKLEKLMIRLGLFTVLYTVPAAVVVACLFYEQHNRPRWEATH--- 565
RIR+++K DG TKT KLEKLM+R+G+F+VLYTVPA +V+AC FYEQ R +WE +
Sbjct: 515 RIRTIMK-HDG-TKTEKLEKLMVRIGVFSVLYTVPATIVIACYFYEQAFRDQWERSWVAQ 572
Query: 566 -------NCPCLR---DLQPDQARRPDYAVFMLKYFMCLVVGITSGVWVWSGKTLESWRS 615
CP L+ P PD+ VFM+KY M L+VGITSG W+WSGKTL SWR
Sbjct: 573 SCKSYAIPCPHLQAGGGAPPHPPMSPDFTVFMIKYLMTLIVGITSGFWIWSGKTLNSWRK 632
Query: 616 LCTRCCWASKG 626
TR + +G
Sbjct: 633 FYTRLTNSKQG 643
>gi|4503833 frizzled 7 [Homo sapiens]
Length = 574
Score = 504 bits (1299), Expect = e-143
Identities = 285/610 (46%), Positives = 360/610 (59%), Gaps = 106/610 (17%)
Query: 35 CQEITVPLCKGIGYNYTYMPNQFNHDTQDEAGLEVHQFWPLVEIQCSPDLKFFLCSMYTP 94
CQ I++PLC I YN T +PN H Q++AGLEVHQF+PLV++QCSP+L+FFLCSMY P
Sbjct: 49 CQPISIPLCTDIAYNQTILPNLLGHTNQEDAGLEVHQFYPLVKVQCSPELRFFLCSMYAP 108
Query: 95 ICLEDYKKPLPPCRSVCERAKAGCAPLMRQYGFAWPDRMRCDRLPEQGNPDTLCMDYNRT 154
+C + +PPCRS+CERA+ GC LM ++GF WP+R+RC+ P G + +C+ N +
Sbjct: 109 VCTV-LDQAIPPCRSLCERARQGCEALMNKFGFQWPERLRCENFPVHGAGE-ICVGQNTS 166
Query: 155 DLT-------TAAPSPPRRLPPPPPGEQPPSGS-GHGRP--PGARPPHRGGGRGGGGGDA 204
D + TA P+ P LP P PP S G GRP P + P
Sbjct: 167 DGSGGPGGGPTAYPTAPY-LPDLPFTALPPGASDGRGRPAFPFSCPRQ-----------L 214
Query: 205 AAPPARGGGGGGKARPPGGGAAPCEPGCQCRAPMVSVSSERHPLYNRVKTGQIANCALPC 264
PP G G+ R G APCEPG AN +
Sbjct: 215 KVPPYLGYRFLGE-RDCG---APCEPGR-------------------------ANGLM-- 243
Query: 265 HNPFFSQDERAFTVFWIGLWSVLCFVSTFATVSTFLIDMERFKYPERPIIFLSACYLFVS 324
+F ++ER F W+G+WSVLC ST TV T+L+DM RF YPERPIIFLS CY V+
Sbjct: 244 ---YFKEEERRFARLWVGVWSVLCCASTLFTVLTYLVDMRRFSYPERPIIFLSGCYFMVA 300
Query: 325 VGYLVRLVAGHEKVACSGGAPGAGGAGGAGGAAAGAGAAGAGAGGPGGRGEYEELGAVEQ 384
V ++ + V + G A G G
Sbjct: 301 VAHVAGFLLEDRAVCVERFSDD-----GYRTVAQGTKKEG-------------------- 335
Query: 385 HVRYETTGPALCTVVFLLVYFFGMASSIWWVILSLTWFLAAGMKWGNEAIAGYSQYFHLA 444
CT++F+++YFFGMASSIWWVILSLTWFLAAGMKWG+EAI SQYFHLA
Sbjct: 336 -----------CTILFMVLYFFGMASSIWWVILSLTWFLAAGMKWGHEAIEANSQYFHLA 384
Query: 445 AWLVPSVKSIAVLALSSVDGDPVAGICYVGNQSLDNLRGFVLAPLVIYLFIGTMFLLAGF 504
AW VP+VK+I +LA+ VDGD ++G+CYVG S+D LRGFVLAPL +YLFIGT FLLAGF
Sbjct: 385 AWAVPAVKTITILAMGQVDGDLLSGVCYVGLSSVDALRGFVLAPLFVYLFIGTSFLLAGF 444
Query: 505 VSLFRIRSVIKQQDGPTKTHKLEKLMIRLGLFTVLYTVPAAVVVACLFYEQHNRPRWEAT 564
VSLFRIR+++K DG TKT KLEKLM+R+G+F+VLYTVPA +V+AC FYEQ R WE T
Sbjct: 445 VSLFRIRTIMK-HDG-TKTEKLEKLMVRIGVFSVLYTVPATIVLACYFYEQAFREHWERT 502
Query: 565 --------HNCPCLRDLQPDQARRPDYAVFMLKYFMCLVVGITSGVWVWSGKTLESWRSL 616
+ PC P + PD+ VFM+KY M ++VGIT+G W+WSGKTL+SWR
Sbjct: 503 WLLQTCKSYAVPCPPGHFPPMS--PDFTVFMIKYLMTMIVGITTGFWIWSGKTLQSWRRF 560
Query: 617 CTRCCWASKG 626
R +SKG
Sbjct: 561 YHRLSHSSKG 570
>gi|6005762 frizzled 10 [Homo sapiens]
Length = 581
Score = 472 bits (1215), Expect = e-133
Identities = 260/617 (42%), Positives = 352/617 (57%), Gaps = 105/617 (17%)
Query: 18 LLQRSSGAAAASAKELA------CQEITVPLCKGIGYNYTYMPNQFNHDTQDEAGLEVHQ 71
+LQ AA S+ ++ CQ I +P+CK IGYN T MPN H+ Q EA +++H+
Sbjct: 11 VLQVMGSCAAISSMDMERPGDGKCQPIEIPMCKDIGYNMTRMPNLMGHENQREAAIQLHE 70
Query: 72 FWPLVEIQCSPDLKFFLCSMYTPICLEDYKKPLPPCRSVCERAKAGCAPLMRQYGFAWPD 131
F PLVE C L+FFLCS+Y P+C E P+P CR +CE+A+ C+P+M Q+ F WPD
Sbjct: 71 FAPLVEYGCHGHLRFFLCSLYAPMCTEQVSTPIPACRVMCEQARLKCSPIMEQFNFKWPD 130
Query: 132 RMRCDRLPEQGNPDTLCMDYNRTDLTTAAPSPPRRLPPPPPGEQPPSGSGHGRPPGARP- 190
+ C +LP + +P+ LCM+ P ++P GSG PP RP
Sbjct: 131 SLDCRKLPNKNDPNYLCME-----------------APNNGSDEPTRGSGLF-PPLFRPQ 172
Query: 191 -PHRGGGRGGGGGDAAAPPARGGGGGGKARPPGGGAAPCEPGCQCRAPMVSVSSERHPLY 249
PH A P + GG PG G PG +
Sbjct: 173 RPH----------SAQEHPLKDGG-------PGRGGCD-NPG---------------KFH 199
Query: 250 NRVKTGQIANCALPCHNPFFSQDERAFTVFWIGLWSVLCFVSTFATVSTFLIDMERFKYP 309
+ K+ A P + ++S++++ F V W+ +W+VLCF S+ TV TFLID RF+YP
Sbjct: 200 HVEKSASCAPLCTPGVDVYWSREDKRFAVVWLAIWAVLCFFSSAFTVLTFLIDPARFRYP 259
Query: 310 ERPIIFLSACYLFVSVGYLVRLVAGHEKVACSGGAPGAGGAGGAGGAAAGAGAAGAGAGG 369
ERPIIFLS CY SVGYL+RL AG E +AC +
Sbjct: 260 ERPIIFLSMCYCVYSVGYLIRLFAGAESIACDRDSG------------------------ 295
Query: 370 PGGRGEYEELGAVEQHVRYETTGPALCTVVFLLVYFFGMASSIWWVILSLTWFLAAGMKW 429
+L +++ + E+TG CT+VFL++Y+FGMASS+WWV+L+LTWFLAAG KW
Sbjct: 296 --------QLYVIQEGL--ESTG---CTLVFLVLYYFGMASSLWWVVLTLTWFLAAGKKW 342
Query: 430 GNEAIAGYSQYFHLAAWLVPSVKSIAVLALSSVDGDPVAGICYVGNQSLDNLRGFVLAPL 489
G+EAI S YFHLAAW +P+VK+I +L + V GD + G+CYVG+ ++ L GFVL PL
Sbjct: 343 GHEAIEANSSYFHLAAWAIPAVKTILILVMRRVAGDELTGVCYVGSMDVNALTGFVLIPL 402
Query: 490 VIYLFIGTMFLLAGFVSLFRIRSVIKQQDGPTKTHKLEKLMIRLGLFTVLYTVPAAVVVA 549
YL IGT F+L+GFV+LF IR V+K G T KLEKLM+R+GLF+VLYTVPA V+A
Sbjct: 403 ACYLVIGTSFILSGFVALFHIRRVMK--TGGENTDKLEKLMVRIGLFSVLYTVPATCVIA 460
Query: 550 CLFYEQHNRPRWE---ATHNCPCLRDLQP----DQARRPDYAVFMLKYFMCLVVGITSGV 602
C FYE+ N W+ A H C + A P +FM+K FM LVVGITSG+
Sbjct: 461 CYFYERLNMDYWKILAAQHKCKMNNQTKTLDCLMAASIPAVEIFMVKIFMLLVVGITSGM 520
Query: 603 WVWSGKTLESWRSLCTR 619
W+W+ KTL+SW+ +C+R
Sbjct: 521 WIWTSKTLQSWQQVCSR 537
>gi|4503835 frizzled 9 [Homo sapiens]
Length = 591
Score = 452 bits (1162), Expect = e-127
Identities = 263/639 (41%), Positives = 345/639 (53%), Gaps = 118/639 (18%)
Query: 20 QRSSGAAAASAKELACQEITVPLCKGIGYNYTYMPNQFNHDTQDEAGLEVHQFWPLVEIQ 79
+R GAA CQ + +P+C+GIGYN T MPN H +Q EA E+ +F PLV+
Sbjct: 31 ERGRGAAP-------CQAVEIPMCRGIGYNLTRMPNLLGHTSQGEAAAELAEFAPLVQYG 83
Query: 80 CSPDLKFFLCSMYTPICLEDYKKPLPPCRSVCERAKAGCAPLMRQYGFAWPDRMRCDRLP 139
C L+FFLCS+Y P+C + P+P CR +CE+A+ CAP+M Q+ F WPD + C RLP
Sbjct: 84 CHSHLRFFLCSLYAPMCTDQVSTPIPACRPMCEQARLRCAPIMEQFNFGWPDSLDCARLP 143
Query: 140 EQGNPDTLCMDYNRTDLTTAAPSPPRRLPPPPPGEQPPSGSGHGRPPGARPPHRGGGRGG 199
+ +P LCM+ + TA P+ P + G G P A P R
Sbjct: 144 TRNDPHALCME--APENATAGPAEPHK--------------GLGMLPVAPRPAR------ 181
Query: 200 GGGDAAAPPARGGGGGGKARPPGGGAAPCEPGCQCRAPMVSVSSERHPLYNRVKTGQIAN 259
PP G P GG+ CE + E+ + ++
Sbjct: 182 -------PP-------GDLGPGAGGSGTCE------------NPEKFQYVEKSRS----- 210
Query: 260 CALPCH---NPFFSQDERAFTVFWIGLWSVLCFVSTFATVSTFLIDMERFKYPERPIIFL 316
CA C F+S+ ++ F + W+ +WS LCF ST TV TFL++ RF+YPERPIIFL
Sbjct: 211 CAPRCGPGVEVFWSRRDKDFALVWMAVWSALCFFSTAFTVLTFLLEPHRFQYPERPIIFL 270
Query: 317 SACYLFVSVGYLVRLVAGHEKVACSGGAPGAGGAGGAGGAAAGAGAAGAGAGGPGGRGEY 376
S CY S+ +L+R VAG + VAC
Sbjct: 271 SMCYNVYSLAFLIRAVAGAQSVACD----------------------------------- 295
Query: 377 EELGAVEQHVRYETTGPALCTVVFLLVYFFGMASSIWWVILSLTWFLAAGMKWGNEAIAG 436
+E GA+ +V E CT+VFLL+Y+FGMASS+WWV+L+LTWFLAAG KWG+EAI
Sbjct: 296 QEAGAL--YVIQEGLENTGCTLVFLLLYYFGMASSLWWVVLTLTWFLAAGKKWGHEAIEA 353
Query: 437 YSQYFHLAAWLVPSVKSIAVLALSSVDGDPVAGICYVGNQSLDNLRGFVLAPLVIYLFIG 496
+ YFH+AAW +P++K+I +L L V GD + G+CYV + L GFVL PL YL +G
Sbjct: 354 HGSYFHMAAWGLPALKTIVILTLRKVAGDELTGLCYVASTDAAALTGFVLVPLSGYLVLG 413
Query: 497 TMFLLAGFVSLFRIRSVIKQQDGPTKTHKLEKLMIRLGLFTVLYTVPAAVVVACLFYEQH 556
+ FLL GFV+LF IR ++K G T T KLEKLM+++G+F++LYTVPA V+ C YE+
Sbjct: 414 SSFLLTGFVALFHIRKIMK--TGGTNTEKLEKLMVKIGVFSILYTVPATCVIVCYVYERL 471
Query: 557 NRPRW--EATHNCPCL--------RDLQPDQARRPDYAVFMLKYFMCLVVGITSGVWVWS 606
N W AT PC RD P AVFMLK FM LVVGITSGVWVWS
Sbjct: 472 NMDFWRLRATEQ-PCAAAAGPGGRRDCSLPGGSVPTVAVFMLKIFMSLVVGITSGVWVWS 530
Query: 607 GKTLESWRSLCTRCCWASKGAAVGGGAGATAAGGGGGPG 645
KT ++W+SLC R K AA A A A G G G
Sbjct: 531 SKTFQTWQSLCYR-----KIAAGRARAKACRAPGSYGRG 564
>gi|22547161 frizzled 4 [Homo sapiens]
Length = 537
Score = 338 bits (868), Expect = 8e-93
Identities = 192/430 (44%), Positives = 251/430 (58%), Gaps = 60/430 (13%)
Query: 214 GGGKARPPGGGAAPCEPGCQCRAPMVSVSSERHPLYNRVKTGQIANCALPCHNP--FFSQ 271
G G P P +PG +C + V +S+++ R NC L C +S+
Sbjct: 161 GPGDEEVPLPHKTPIQPGEECHS--VGTNSDQYIWVKRS-----LNCVLKCGYDAGLYSR 213
Query: 272 DERAFTVFWIGLWSVLCFVSTFATVSTFLIDMERFKYPERPIIFLSACYLFVSVGYLVRL 331
+ FT W+ +W+ LCF+ST TV TFLID RF YPERPIIFLS CY S+ Y+VRL
Sbjct: 214 SAKEFTDIWMAVWASLCFISTAFTVLTFLIDSSRFSYPERPIIFLSMCYNIYSIAYIVRL 273
Query: 332 VAGHEKVACSGGAPGAGGAGGAGGAAAGAGAAGAGAGGPGGRGEYEELGAVEQHVRYETT 391
G E+++C ++EE A E + E
Sbjct: 274 TVGRERISC----------------------------------DFEE--AAEPVLIQEGL 297
Query: 392 GPALCTVVFLLVYFFGMASSIWWVILSLTWFLAAGMKWGNEAIAGYSQYFHLAAWLVPSV 451
C ++FLL+YFFGMASSIWWVIL+LTWFLAAG+KWG+EAI +S YFH+AAW +P+V
Sbjct: 298 KNTGCAIIFLLMYFFGMASSIWWVILTLTWFLAAGLKWGHEAIEMHSSYFHIAAWAIPAV 357
Query: 452 KSIAVLALSSVDGDPVAGICYVGNQSLDNLRGFVLAPLVIYLFIGTMFLLAGFVSLFRIR 511
K+I +L + VD D + G+CYVGNQ+LD L GFV+APL YL IGT+F+ AG V+LF+IR
Sbjct: 358 KTIVILIMRLVDADELTGLCYVGNQNLDALTGFVVAPLFTYLVIGTLFIAAGLVALFKIR 417
Query: 512 SVIKQQDGPTKTHKLEKLMIRLGLFTVLYTVPAAVVVACLFYEQHNRPRWEATHNCPCLR 571
S + Q+DG TKT KLE+LM+++G+F+VLYTVPA V+AC FYE N W
Sbjct: 418 SNL-QKDG-TKTDKLERLMVKIGVFSVLYTVPATCVIACYFYEISN---WA--------- 463
Query: 572 DLQPDQARRPDYAVFMLKYFMCLVVGITSGVWVWSGKTLESWRSLCTRCCWASKGAAVGG 631
L A + AV MLK FM L+VGITSG+W+WS KTL +W+ R + K
Sbjct: 464 -LFRYSADDSNMAVEMLKIFMSLLVGITSGMWIWSAKTLHTWQKCSNRLVNSGKVKREKR 522
Query: 632 GAGATAAGGG 641
G G G G
Sbjct: 523 GNGWVKPGKG 532
Score = 123 bits (308), Expect = 7e-28
Identities = 55/147 (37%), Positives = 85/147 (57%), Gaps = 2/147 (1%)
Query: 4 GYLLEVTSLLAALALLQRSSGAAAASAKELACQEITVPLCKGIGYNYTYMPNQFNHDTQD 63
G L + LL L LL + G +E C I + +C+ +GYN T MPN H+ Q
Sbjct: 16 GVGLSLGLLLQLLLLLGPARGFG--DEEERRCDPIRISMCQNLGYNVTKMPNLVGHELQT 73
Query: 64 EAGLEVHQFWPLVEIQCSPDLKFFLCSMYTPICLEDYKKPLPPCRSVCERAKAGCAPLMR 123
+A L++ F PL++ CS L+FFLCS+Y P+C E P+ PC +C K C P+++
Sbjct: 74 DAELQLTTFTPLIQYGCSSQLQFFLCSVYVPMCTEKINIPIGPCGGMCLSVKRRCEPVLK 133
Query: 124 QYGFAWPDRMRCDRLPEQGNPDTLCMD 150
++GFAWP+ + C + P Q + + +CM+
Sbjct: 134 EFGFAWPESLNCSKFPPQNDHNHMCME 160
>gi|8393378 frizzled 3 [Homo sapiens]
Length = 666
Score = 272 bits (695), Expect = 9e-73
Identities = 146/367 (39%), Positives = 210/367 (57%), Gaps = 47/367 (12%)
Query: 257 IANCALPCHNPFFSQDERAFTVFWIGLWSVLCFVSTFATVSTFLIDMERFKYPERPIIFL 316
+ +C+ PC N +F ++E +F ++IGL S++C +T T TFLID+ RF+YPERPIIF
Sbjct: 182 VRDCSPPCPNMYFRREELSFARYFIGLISIICLSATLFTFLTFLIDVTRFRYPERPIIFY 241
Query: 317 SACYLFVSVGYLVRLVAGHEKVACSGGAPGAGGAGGAGGAAAGAGAAGAGAGGPGGRGEY 376
+ CY+ VS+ + + + ++VAC+ P A A G+
Sbjct: 242 AVCYMMVSLIFFIGFLL-EDRVACNASIP----------AQYKASTVTQGSHNKA----- 285
Query: 377 EELGAVEQHVRYETTGPALCTVVFLLVYFFGMASSIWWVILSLTWFLAAGMKWGNEAIAG 436
CT++F+++YFF MA S+WWVIL++TWFLAA KWG+EAI
Sbjct: 286 -------------------CTMLFMILYFFTMAGSVWWVILTITWFLAAVPKWGSEAIEK 326
Query: 437 YSQYFHLAAWLVPSVKSIAVLALSSVDGDPVAGICYVGNQSLDNLRGFVLAPLVIYLFIG 496
+ FH +AW +P +I +LA++ ++GD ++G+C+VG +D LR FVLAPL +Y+ +G
Sbjct: 327 KALLFHASAWGIPGTLTIILLAMNKIEGDNISGVCFVGLYDVDALRYFVLAPLCLYVVVG 386
Query: 497 TMFLLAGFVSLFRIRSVIKQQDGPTKTHKLEKLMIRLGLFTVLYTVPAAVVVACLFYEQH 556
LLAG +SL R+R I + KL K MIR+G+F++LY VP VV+ C FYEQ
Sbjct: 387 VSLLLAGIISLNRVRIEIPLE--KENQDKLVKFMIRIGVFSILYLVPLLVVIGCYFYEQA 444
Query: 557 NRPRWEAT--------HNCPCLRDLQPDQARRPDYAVFMLKYFMCLVVGITSGVWVWSGK 608
R WE T ++ PC Q Q RPD +F++KY M L+VGI S WV S K
Sbjct: 445 YRGIWETTWIQERCREYHIPC--PYQVTQMSRPDLILFLMKYLMALIVGIPSVFWVGSKK 502
Query: 609 TLESWRS 615
T W S
Sbjct: 503 TCFEWAS 509
Score = 113 bits (283), Expect = 5e-25
Identities = 53/134 (39%), Positives = 78/134 (58%), Gaps = 2/134 (1%)
Query: 34 ACQEITVPLCKGIGYNYTYMPNQFNHDTQDEAGLEVHQFWPLVEIQCSPDLKFFLCSMYT 93
+C+ IT+ +C+ + YN T+MPN NH Q A L + F P+V + CS D + FLC++Y
Sbjct: 27 SCEPITLRMCQDLPYNTTFMPNLLNHYDQQTAALAMEPFHPMVNLDCSRDFRPFLCALYA 86
Query: 94 PICLEDYKKPLPPCRSVCERAKAGCAPLMRQYGFAWPDRMRCDRLPEQGNPDTLCMDYNR 153
PIC+E Y + PCR +C+RA + C+ LM +G WP+ M C R P+ P +D N
Sbjct: 87 PICME-YGRVTLPCRRLCQRAYSECSKLMEMFGVPWPEDMECSRFPDCDEPYPRLVDLNL 145
Query: 154 T-DLTTAAPSPPRR 166
+ T AP +R
Sbjct: 146 AGEPTEGAPVAVQR 159
>gi|34734079 frizzled 6 [Homo sapiens]
Length = 706
Score = 262 bits (670), Expect = 7e-70
Identities = 149/371 (40%), Positives = 203/371 (54%), Gaps = 47/371 (12%)
Query: 257 IANCALPCHNPFFSQDERAFTVFWIGLWSVLCFVSTFATVSTFLIDMERFKYPERPIIFL 316
I CA PC N +F DE F +IG S+ C +T T TFLID+ RF+YPERPII+
Sbjct: 178 IDQCAPPCPNMYFKSDELEFAKSFIGTVSIFCLCATLFTFLTFLIDVRRFRYPERPIIYY 237
Query: 317 SACYLFVSVGYLVRLVAGHEKVACSGGAPGAGGAGGAGGAAAGAGAAGAGAGGPGGRGEY 376
S CY VS+ Y + + G + AC+ A G+
Sbjct: 238 SVCYSIVSLMYFIGFLLG-DSTACNK------------------------ADEKLELGDT 272
Query: 377 EELGAVEQHVRYETTGPALCTVVFLLVYFFGMASSIWWVILSLTWFLAAGMKWGNEAIAG 436
LG+ + CTV+F+L+YFF MA ++WWVIL++TWFLAAG KW EAI
Sbjct: 273 VVLGSQNK----------ACTVLFMLLYFFTMAGTVWWVILTITWFLAAGRKWSCEAIEQ 322
Query: 437 YSQYFHLAAWLVPSVKSIAVLALSSVDGDPVAGICYVGNQSLDNLRGFVLAPLVIYLFIG 496
+ +FH AW P ++ +LA++ V+GD ++G+C+VG LD R FVL PL + +F+G
Sbjct: 323 KAVWFHAVAWGTPGFLTVMLLAMNKVEGDNISGVCFVGLYDLDASRYFVLLPLCLCVFVG 382
Query: 497 TMFLLAGFVSLFRIRSVIKQQDGPTKTHKLEKLMIRLGLFTVLYTVPAAVVVACLFYEQH 556
LLAG +SL +R VI Q DG + KL+K MIR+G+F+ LY VP ++ C YEQ
Sbjct: 383 LSLLLAGIISLNHVRQVI-QHDGRNQ-EKLKKFMIRIGVFSGLYLVPLVTLLGCYVYEQV 440
Query: 557 NRPRWEAT--------HNCPCLRDLQPDQARRPDYAVFMLKYFMCLVVGITSGVWVWSGK 608
NR WE T ++ PC Q RP+ A+FM+KY M L+VGI++ WV S K
Sbjct: 441 NRITWEITWVSDHCRQYHIPC--PYQAKAKARPELALFMIKYLMTLIVGISAVFWVGSKK 498
Query: 609 TLESWRSLCTR 619
T W R
Sbjct: 499 TCTEWAGFFKR 509
Score = 103 bits (258), Expect = 4e-22
Identities = 42/104 (40%), Positives = 62/104 (59%), Gaps = 1/104 (0%)
Query: 35 CQEITVPLCKGIGYNYTYMPNQFNHDTQDEAGLEVHQFWPLVEIQCSPDLKFFLCSMYTP 94
C+ ITVP C + YN T+ PN H Q A +E+ F PL ++CSP+++ FLC + P
Sbjct: 24 CEPITVPRCMKMAYNMTFFPNLMGHYDQSIAAVEMEHFLPLANLECSPNIETFLCKAFVP 83
Query: 95 ICLEDYKKPLPPCRSVCERAKAGCAPLMRQYGFAWPDRMRCDRL 138
C+E +PPCR +CE+ + C L+ +G WP+ + CDRL
Sbjct: 84 TCIEQI-HVVPPCRKLCEKVYSDCKKLIDTFGIRWPEELECDRL 126
>gi|5032099 smoothened [Homo sapiens]
Length = 787
Score = 159 bits (402), Expect = 8e-39
Identities = 112/401 (27%), Positives = 182/401 (45%), Gaps = 65/401 (16%)
Query: 233 QCRAPMVSVSSERHPLYNRVKTGQIANCALPCHNPFFSQDERAFTVFWIGLWSVLCFVST 292
QC P+V + + Y V+ C + C NP F++ E +I + + + T
Sbjct: 192 QCEVPLVRTDNPKS-WYEDVE-----GCGIQCQNPLFTEAEHQDMHSYIAAFGAVTGLCT 245
Query: 293 FATVSTFLIDMERF-KYPERPIIFLSACYLFVSVGYLVRLVAG-HEKVACSGGAPGAGGA 350
T++TF+ D +YP + +++AC+ S+G+L + + G ++ C
Sbjct: 246 LFTLATFVADWRNSNRYPAVILFYVNACFFVGSIGWLAQFMDGARREIVCR--------- 296
Query: 351 GGAGGAAAGAGAAGAGAGGPGGRGEYEELGAVEQHVRYETTGPAL-CTVVFLLVYFFGMA 409
A G GE T+ L C ++F++VY+ MA
Sbjct: 297 ----------------ADGTMRLGE-------------PTSNETLSCVIIFVIVYYALMA 327
Query: 410 SSIWWVILSLTW---FLAAGMKWGNEAIAGYSQYFHLAAWLVPSVKSIAVLALSSVDGDP 466
+W+V+L+ W F A G + + ++G + YFHL W +P V ++A+LA++ VDGD
Sbjct: 328 GVVWFVVLTYAWHTSFKALGTTY--QPLSGKTSYFHLLTWSLPFVLTVAILAVAQVDGDS 385
Query: 467 VAGICYVGNQSLDNLRGFVLAPLVIYLFIGTMFLLAGFVSLFRIRSVIKQQDGPTKTHKL 526
V+GIC+VG ++ GFVLAP+ + L +G FL+ G ++LF I+S K+
Sbjct: 386 VSGICFVGYKNYRYRAGFVLAPIGLVLIVGGYFLIRGVMTLFSIKSNHPGLLSEKAASKI 445
Query: 527 EKLMIRLGLFTVLYTVPAAVVVACLFYEQHNRPRWEATHN----CPC-----LRDLQP-- 575
+ M+RLG+F L + +C FY+ N+ WE + C L QP
Sbjct: 446 NETMLRLGIFGFLAFGFVLITFSCHFYDFFNQAEWERSFRDYVLCQANVTIGLPTKQPIP 505
Query: 576 --DQARRPDYAVFMLKYFMCLVVGITSGVWVWSGKTLESWR 614
+ RP V + F GI WVW+ TL WR
Sbjct: 506 DCEIKNRPSLLVEKINLFAMFGTGIAMSTWVWTKATLLIWR 546
Score = 43.5 bits (101), Expect = 7e-04
Identities = 33/111 (29%), Positives = 56/111 (50%), Gaps = 9/111 (8%)
Query: 35 CQEITVPLCKG--IGYNYTYMPNQFNHDTQDEAGLEVHQFWPLVEI-QCSPDLKFFLCSM 91
C+ + +C G + Y T + D+Q+EA ++ + L +C ++ LC++
Sbjct: 70 CEPLRYNVCLGSVLPYGATSTLLAGDSDSQEEAHGKLVLWSGLRNAPRCWAVIQPLLCAV 129
Query: 92 YTPICLEDYKKPLPPCRSVCERAKAGCAPLMRQYGFAWPDRMRC--DRLPE 140
Y P C D + P R++C+ + CA + R+ G WPD +RC DR PE
Sbjct: 130 YMPKCENDRVEL--PSRTLCQATRGPCAIVERERG--WPDFLRCTPDRFPE 176
>gi|38455388 frizzled-related protein [Homo sapiens]
Length = 325
Score = 132 bits (331), Expect = 1e-30
Identities = 66/138 (47%), Positives = 88/138 (63%), Gaps = 7/138 (5%)
Query: 4 GYLLEVTSLLAALAL-LQRSSGAAAASAKELACQEITVPLCKGIGYNYTYMPNQFNHDTQ 62
G LL LLA AL L R GA AA AC+ + +PLCK + +N T MPN +H TQ
Sbjct: 8 GMLLLRAGLLALAALCLLRVPGARAA-----ACEPVRIPLCKSLPWNMTKMPNHLHHSTQ 62
Query: 63 DEAGLEVHQFWPLVEIQCSPDLKFFLCSMYTPICLEDYK-KPLPPCRSVCERAKAGCAPL 121
A L + QF L+ CSPDL FFLC+MY PIC D++ +P+ PC+SVCERA+ GC P+
Sbjct: 63 ANAILAIEQFEGLLGTHCSPDLLFFLCAMYAPICTIDFQHEPIKPCKSVCERARQGCEPI 122
Query: 122 MRQYGFAWPDRMRCDRLP 139
+ +Y +WP+ + C+ LP
Sbjct: 123 LIKYRHSWPENLACEELP 140
>gi|170784838 secreted frizzled-related protein 4 [Homo sapiens]
Length = 346
Score = 121 bits (303), Expect = 2e-27
Identities = 55/130 (42%), Positives = 80/130 (61%), Gaps = 5/130 (3%)
Query: 11 SLLAALALLQRSSGAAAASAKELACQEITVPLCKGIGYNYTYMPNQFNHDTQDEAGLEVH 70
S+L AL L A + C+ + +P+C+ + +N T MPN +H TQ+ A L +
Sbjct: 4 SILVALCLWLH----LALGVRGAPCEAVRIPMCRHMPWNITRMPNHLHHSTQENAILAIE 59
Query: 71 QFWPLVEIQCSPDLKFFLCSMYTPIC-LEDYKKPLPPCRSVCERAKAGCAPLMRQYGFAW 129
Q+ LV++ CS L+FFLC+MY PIC LE P+ PC+SVC+RA+ C PLM+ Y +W
Sbjct: 60 QYEELVDVNCSAVLRFFLCAMYAPICTLEFLHDPIKPCKSVCQRARDDCEPLMKMYNHSW 119
Query: 130 PDRMRCDRLP 139
P+ + CD LP
Sbjct: 120 PESLACDELP 129
>gi|48475052 secreted frizzled-related protein 2 precursor [Homo
sapiens]
Length = 295
Score = 107 bits (268), Expect = 3e-23
Identities = 54/140 (38%), Positives = 76/140 (54%), Gaps = 6/140 (4%)
Query: 29 SAKELACQEI--TVPLCKGIGYNYTYMPNQFNHDTQDEAGLEVHQFWPLVEIQCSPDLKF 86
S K C+ I + LC GI Y +PN H+T E + + PLV QC PD K
Sbjct: 34 SYKRSNCKPIPANLQLCHGIEYQNMRLPNLLGHETMKEVLEQAGAWIPLVMKQCHPDTKK 93
Query: 87 FLCSMYTPICLEDYKKPLPPCRSVCERAKAGCAPLMRQYGFAWPDRMRCDRLPEQGNPDT 146
FLCS++ P+CL+D + + PC S+C + K CAP+M +GF WPD + CDR P+ +
Sbjct: 94 FLCSLFAPVCLDDLDETIQPCHSLCVQVKDRCAPVMSAFGFPWPDMLECDRFPQDND--- 150
Query: 147 LCMDYNRTD-LTTAAPSPPR 165
LC+ +D L A P+
Sbjct: 151 LCIPLASSDHLLPATEEAPK 170
>gi|188528609 secreted frizzled-related protein 5 [Homo sapiens]
Length = 317
Score = 103 bits (256), Expect = 7e-22
Identities = 46/122 (37%), Positives = 69/122 (56%), Gaps = 6/122 (4%)
Query: 40 VPLCKGIGYNYTYMPNQFNHDTQDEAGLEVHQFWPLVEIQCSPDLKFFLCSMYTPICLED 99
+PLC +GY +PN H++ E + + PL+ +C D + FLCS++ P+CL+
Sbjct: 60 LPLCHTVGYKRMRLPNLLEHESLAEVKQQASSWLPLLAKRCHSDTQVFLCSLFAPVCLD- 118
Query: 100 YKKPLPPCRSVCERAKAGCAPLMRQYGFAWPDRMRCDRLPEQGNPDTLCMDYNRTDLTTA 159
+P+ PCRS+CE +AGCAPLM YGF WP+ + C + P + LC+ L
Sbjct: 119 --RPIYPCRSLCEAVRAGCAPLMEAYGFPWPEMLHCHKFPLDND---LCIAVQFGHLPAT 173
Query: 160 AP 161
AP
Sbjct: 174 AP 175
>gi|56117838 secreted frizzled-related protein 1 [Homo sapiens]
Length = 314
Score = 93.2 bits (230), Expect = 7e-19
Identities = 42/133 (31%), Positives = 69/133 (51%), Gaps = 7/133 (5%)
Query: 42 LCKGIGYNYTYMPNQFNHDTQDEAGLEVHQFWPLVEIQCSPDLKFFLCSMYTPICLEDYK 101
LC +GY +PN H+T E + + PL+ C + FLCS++ P+CL+
Sbjct: 67 LCHNVGYKKMVLPNLLEHETMAEVKQQASSWVPLLNKNCHAGTQVFLCSLFAPVCLD--- 123
Query: 102 KPLPPCRSVCERAKAGCAPLMRQYGFAWPDRMRCDRLPEQGNPDTLCMDYNRTDLTTAAP 161
+P+ PCR +CE + C P+M+ +GF WP+ ++CD+ PE +C+ + T A+
Sbjct: 124 RPIYPCRWLCEAVRDSCEPVMQFFGFYWPEMLKCDKFPE----GDVCIAMTPPNATEASK 179
Query: 162 SPPRRLPPPPPGE 174
+ PP E
Sbjct: 180 PQGTTVCPPCDNE 192
>gi|29244926 corin [Homo sapiens]
Length = 1042
Score = 89.7 bits (221), Expect = 8e-18
Identities = 42/117 (35%), Positives = 63/117 (53%), Gaps = 2/117 (1%)
Query: 35 CQEITVPLCKGIGYNYTYMPNQFNHDTQDEAGL--EVHQFWPLVEIQCSPDLKFFLCSMY 92
C+ IT+ LC + YN T PN F H TQ EA + E F LV+ C L FF C++
Sbjct: 455 CEPITLELCMNLPYNSTSYPNYFGHRTQKEASISWESSLFPALVQTNCYKYLMFFSCTIL 514
Query: 93 TPICLEDYKKPLPPCRSVCERAKAGCAPLMRQYGFAWPDRMRCDRLPEQGNPDTLCM 149
P C + + +PPCR++CE +K C ++ G WP+ C + PE+ + + C+
Sbjct: 515 VPKCDVNTGEHIPPCRALCEHSKERCESVLGIVGLQWPEDTDCSQFPEENSDNQTCL 571
Score = 57.0 bits (136), Expect = 6e-08
Identities = 36/121 (29%), Positives = 55/121 (45%), Gaps = 8/121 (6%)
Query: 34 ACQEITVPLCKGIGYNYTYMPN-QFNHDTQDEAGLEVHQFWPLVEIQCSPDLKFFLCSMY 92
AC IT C+ + Y+ T P + + E L+ + L + C + F C++
Sbjct: 138 ACMNITHSQCQMLPYHATLTPLLSVVRNMEMEKFLKFFTY--LHRLSCYQHIMLFGCTLA 195
Query: 93 TPICL--EDYKKPLPPCRSVCERAKAGCAPLMRQYGFAWPDRMRCDRL---PEQGNPDTL 147
P C+ D L PCRS CE AK GC ++ ++WPD +RC + E N +
Sbjct: 196 FPECIIDGDDSHGLLPCRSFCEAAKEGCESVLGMVNYSWPDFLRCSQFRNQTESSNVSRI 255
Query: 148 C 148
C
Sbjct: 256 C 256
>gi|13899255 membrane frizzled-related protein [Homo sapiens]
Length = 579
Score = 69.3 bits (168), Expect = 1e-11
Identities = 39/110 (35%), Positives = 54/110 (49%), Gaps = 4/110 (3%)
Query: 32 ELACQEITVPLCKGIGYNYTYMPNQF-NHDTQDEAGLEVHQFWPLVEIQCSPDLKFFLCS 90
ELAC+ + V +C G+ YN T PN + TQ+E + + L + C + LC
Sbjct: 463 ELACEPVQVEMCLGLSYNTTAFPNIWVGMITQEEVVEVLSGYKSLTSLPCYQHFRRLLCG 522
Query: 91 MYTPICLEDYKKPLPPCRSVCERAKAGCAPLMRQYGFAWPDRMRCDRLPE 140
+ P C LPPCRSVC+ A+ C + G WP C+RLPE
Sbjct: 523 LLVPRCTP-LGSVLPPCRSVCQEAEHQCQSGLALLGTPWP--FNCNRLPE 569
>gi|110347449 POU domain, class 4, transcription factor 1 [Homo
sapiens]
Length = 419
Score = 64.3 bits (155), Expect = 4e-10
Identities = 31/42 (73%), Positives = 31/42 (73%), Gaps = 4/42 (9%)
Query: 626 GAAVGGGAGATAAGGGGGPGGGGG--GGP--GGGGGPGGGGG 663
GAA GGG GGGGGPGGGGG GGP GGGGGPGGGGG
Sbjct: 135 GAAAGGGGAHDGPGGGGGPGGGGGPGGGPGGGGGGGPGGGGG 176
Score = 60.8 bits (146), Expect = 4e-09
Identities = 27/36 (75%), Positives = 27/36 (75%)
Query: 628 AVGGGAGATAAGGGGGPGGGGGGGPGGGGGPGGGGG 663
A GGAGA A GGG G GGGGGPGGGGGPGGG G
Sbjct: 129 AGAGGAGAAAGGGGAHDGPGGGGGPGGGGGPGGGPG 164
Score = 60.8 bits (146), Expect = 4e-09
Identities = 35/68 (51%), Positives = 41/68 (60%), Gaps = 7/68 (10%)
Query: 630 GGGAGATAAGG-GGGPGGGGGGGP-GGGGGPGGG--GGSLYSDV---STGLTWRSGTASS 682
GGG G GG GGGPGGGGGGGP GGGGGPGGG GGS + S G A++
Sbjct: 148 GGGGGPGGGGGPGGGPGGGGGGGPGGGGGGPGGGLLGGSAHPHPHMHSLGHLSHPAAAAA 207
Query: 683 VSYPKQMP 690
++ P +P
Sbjct: 208 MNMPSGLP 215
Score = 42.7 bits (99), Expect = 0.001
Identities = 17/31 (54%), Positives = 17/31 (54%)
Query: 342 GGAPGAGGAGGAGGAAAGAGAAGAGAGGPGG 372
GG PG GG G G G G G G GGPGG
Sbjct: 150 GGGPGGGGGPGGGPGGGGGGGPGGGGGGPGG 180
Score = 41.6 bits (96), Expect = 0.003
Identities = 31/75 (41%), Positives = 32/75 (42%), Gaps = 13/75 (17%)
Query: 155 DLTTAAPSPPRRLPPPPPGEQPPSGSG--HGRPPGARPPHRGGGRGGGGGDAAAPPARGG 212
DL SP L G +G G H P G GGG GGGGG P GG
Sbjct: 115 DLLDHISSPSLALMAGAGGAGAAAGGGGAHDGPGG------GGGPGGGGGPGGGP---GG 165
Query: 213 GGGGKARPPGGGAAP 227
GGGG P GGG P
Sbjct: 166 GGGG--GPGGGGGGP 178
Score = 40.4 bits (93), Expect = 0.006
Identities = 22/45 (48%), Positives = 22/45 (48%), Gaps = 3/45 (6%)
Query: 333 AGHEKVACSGGAP--GAGGAGGAGGAAA-GAGAAGAGAGGPGGRG 374
AG A GG G GG GG GG G G G G GGPGG G
Sbjct: 131 AGGAGAAAGGGGAHDGPGGGGGPGGGGGPGGGPGGGGGGGPGGGG 175
Score = 39.3 bits (90), Expect = 0.012
Identities = 20/37 (54%), Positives = 21/37 (56%), Gaps = 2/37 (5%)
Query: 338 VACSGGAPGAGGAGGAGGAAAGAGAAG--AGAGGPGG 372
+A GA GAG A G GGA G G G G GGPGG
Sbjct: 125 LALMAGAGGAGAAAGGGGAHDGPGGGGGPGGGGGPGG 161
Score = 37.4 bits (85), Expect = 0.047
Identities = 20/43 (46%), Positives = 22/43 (51%), Gaps = 6/43 (13%)
Query: 338 VACSGGAPGAGGAGGA------GGAAAGAGAAGAGAGGPGGRG 374
+A +GGA A G GGA GG G G G G GG GG G
Sbjct: 128 MAGAGGAGAAAGGGGAHDGPGGGGGPGGGGGPGGGPGGGGGGG 170
Score = 36.6 bits (83), Expect = 0.080
Identities = 22/44 (50%), Positives = 22/44 (50%), Gaps = 11/44 (25%)
Query: 181 GHGRPPGARPPHRGGGRGGGGGDAAAPPARGGGGGGKARPPGGG 224
G G P G P G G GGGGG GGGGGG PGGG
Sbjct: 149 GGGGPGGGGGPGGGPGGGGGGGP-------GGGGGG----PGGG 181
Score = 35.8 bits (81), Expect = 0.14
Identities = 17/31 (54%), Positives = 17/31 (54%), Gaps = 1/31 (3%)
Query: 342 GGAPGAGGAGGAGGAAAGAGAAGAGAGGPGG 372
GG PG GG GG GG G G G G G GG
Sbjct: 156 GGGPG-GGPGGGGGGGPGGGGGGPGGGLLGG 185
Score = 34.7 bits (78), Expect = 0.31
Identities = 24/67 (35%), Positives = 27/67 (40%), Gaps = 8/67 (11%)
Query: 181 GHGRPPGARPPHRGGGRGGGGGDAAAPPARGGGGGGKARPPGGGAAPCEPGCQCRAPMVS 240
G G G H G G GGG G P GGG GG GGG P G ++
Sbjct: 133 GAGAAAGGGGAHDGPGGGGGPGGGGGP---GGGPGG-----GGGGGPGGGGGGPGGGLLG 184
Query: 241 VSSERHP 247
S+ HP
Sbjct: 185 GSAHPHP 191
Score = 33.5 bits (75), Expect = 0.68
Identities = 23/53 (43%), Positives = 23/53 (43%), Gaps = 12/53 (22%)
Query: 170 PPPGEQPPSGSGHGRPPGARPPHRGGGRGGGGGDAAAPPARGGGG--GGKARP 220
P G P G G G PG GGG GG GG P GGG GG A P
Sbjct: 147 PGGGGGPGGGGGPGGGPG------GGGGGGPGGGGGGP----GGGLLGGSAHP 189
Score = 33.1 bits (74), Expect = 0.89
Identities = 22/49 (44%), Positives = 22/49 (44%), Gaps = 11/49 (22%)
Query: 179 GSGHGRPPGARPPHRGGGRGGGGGDAAAPPARGGGGGGKARPPGGGAAP 227
G G G PG P GGG GGGG GG GGG GG A P
Sbjct: 152 GPGGGGGPGGGPGGGGGGGPGGGG--------GGPGGGLL---GGSAHP 189
>gi|62388875 carboxypeptidase Z isoform 2 precursor [Homo sapiens]
Length = 641
Score = 61.2 bits (147), Expect = 3e-09
Identities = 39/134 (29%), Positives = 57/134 (42%), Gaps = 13/134 (9%)
Query: 12 LLAALALLQRSSGAAAASAKELACQEITVPLCKGIGYNYTYMPNQFNHDTQD--EAGLE- 68
LL L + G C ++ + C YN+T PN H + + EA E
Sbjct: 9 LLTVLVVAAARPGCEFERNPAATCVDLQLRTCSDAAYNHTTFPNLLQHRSWEVVEASSEY 68
Query: 69 -----VHQFWPLVEIQCSPDLKFFLCSMYTPICLEDYKKPLPPCRSVCERAKAGCAPLMR 123
+HQ L+E QC+PDL+ C++ P C + + PCR +CE + C P
Sbjct: 69 ILLSVLHQ---LLEGQCNPDLRLLGCAVLAPRCEGGWVRR--PCRHICEGLREVCQPAFD 123
Query: 124 QYGFAWPDRMRCDR 137
AWP + C R
Sbjct: 124 AIDMAWPYFLDCHR 137
>gi|62388877 carboxypeptidase Z isoform 1 [Homo sapiens]
Length = 652
Score = 60.8 bits (146), Expect = 4e-09
Identities = 36/117 (30%), Positives = 54/117 (46%), Gaps = 13/117 (11%)
Query: 29 SAKELACQEITVPLCKGIGYNYTYMPNQFNHDTQD--EAGLE------VHQFWPLVEIQC 80
+A C ++ + C YN+T PN H + + EA E +HQ L+E QC
Sbjct: 37 AADSATCVDLQLRTCSDAAYNHTTFPNLLQHRSWEVVEASSEYILLSVLHQ---LLEGQC 93
Query: 81 SPDLKFFLCSMYTPICLEDYKKPLPPCRSVCERAKAGCAPLMRQYGFAWPDRMRCDR 137
+PDL+ C++ P C + + PCR +CE + C P AWP + C R
Sbjct: 94 NPDLRLLGCAVLAPRCEGGWVRR--PCRHICEGLREVCQPAFDAIDMAWPYFLDCHR 148
>gi|122937319 even-skipped homeobox 2 [Homo sapiens]
Length = 476
Score = 59.7 bits (143), Expect = 9e-09
Identities = 27/44 (61%), Positives = 29/44 (65%)
Query: 621 CWASKGAAVGGGAGATAAGGGGGPGGGGGGGPGGGGGPGGGGGS 664
C +S+ AA A A A G GG GGGGGGG GGGGG G GGGS
Sbjct: 392 CHSSQSAAAAAAAAAAALGSRGGGGGGGGGGGGGGGGAGAGGGS 435
Score = 38.1 bits (87), Expect = 0.028
Identities = 31/89 (34%), Positives = 33/89 (37%), Gaps = 22/89 (24%)
Query: 159 AAPSPPRRLPPPPPGEQPP----------SGSGHGRPPGARPPHRGGGRGGGGGDAAAPP 208
AA S PP G P S + A RGGG GGGGG
Sbjct: 368 AAASSAAAAGAPPSGGSAPCSCLSCHSSQSAAAAAAAAAAALGSRGGGGGGGGG------ 421
Query: 209 ARGGGGGGKARPPGGGAAPCEPGCQCRAP 237
GGGGGG A GG + GC AP
Sbjct: 422 --GGGGGGGAGAGGGS----DFGCSAAAP 444
Score = 37.4 bits (85), Expect = 0.047
Identities = 16/31 (51%), Positives = 18/31 (58%)
Query: 339 ACSGGAPGAGGAGGAGGAAAGAGAAGAGAGG 369
A + A G+ G GG GG G G GAGAGG
Sbjct: 403 AAAAAALGSRGGGGGGGGGGGGGGGGAGAGG 433
Score = 35.4 bits (80), Expect = 0.18
Identities = 15/34 (44%), Positives = 16/34 (47%)
Query: 339 ACSGGAPGAGGAGGAGGAAAGAGAAGAGAGGPGG 372
A + A G GG GG G G G GAG GG
Sbjct: 401 AAAAAAAALGSRGGGGGGGGGGGGGGGGAGAGGG 434
Score = 33.9 bits (76), Expect = 0.52
Identities = 14/25 (56%), Positives = 14/25 (56%)
Query: 348 GGAGGAGGAAAGAGAAGAGAGGPGG 372
GG GG GG G G AGAG G G
Sbjct: 414 GGGGGGGGGGGGGGGAGAGGGSDFG 438
Score = 33.5 bits (75), Expect = 0.68
Identities = 17/38 (44%), Positives = 18/38 (47%), Gaps = 2/38 (5%)
Query: 627 AAVGGGAGATAAGGGGGPGG--GGGGGPGGGGGPGGGG 662
A G AG T + G G G GG GG GG GG G
Sbjct: 145 AESGSAAGTTTSASGSGLGSLHGGSGGSGGSAALGGSG 182
Score = 33.5 bits (75), Expect = 0.68
Identities = 17/56 (30%), Positives = 22/56 (39%)
Query: 335 HEKVACSGGAPGAGGAGGAGGAAAGAGAAGAGAGGPGGRGEYEELGAVEQHVRYET 390
H + + A A A G+ G G G G G GG G G + G R E+
Sbjct: 393 HSSQSAAAAAAAAAAALGSRGGGGGGGGGGGGGGGGAGAGGGSDFGCSAAAPRSES 448
Score = 32.3 bits (72), Expect = 1.5
Identities = 17/40 (42%), Positives = 17/40 (42%)
Query: 625 KGAAVGGGAGATAAGGGGGPGGGGGGGPGGGGGPGGGGGS 664
KG A G A T G G GG GG GG GGS
Sbjct: 142 KGYAESGSAAGTTTSASGSGLGSLHGGSGGSGGSAALGGS 181
Score = 32.0 bits (71), Expect = 2.0
Identities = 15/35 (42%), Positives = 15/35 (42%)
Query: 346 GAGGAGGAGGAAAGAGAAGAGAGGPGGRGEYEELG 380
G GG GG GG GAGA G G E G
Sbjct: 415 GGGGGGGGGGGGGGAGAGGGSDFGCSAAAPRSESG 449
Score = 31.6 bits (70), Expect = 2.6
Identities = 19/51 (37%), Positives = 22/51 (43%), Gaps = 15/51 (29%)
Query: 339 ACSGGAPGAGG---------------AGGAGGAAAGAGAAGAGAGGPGGRG 374
A + GAP +GG A A AAA G+ G G GG GG G
Sbjct: 373 AAAAGAPPSGGSAPCSCLSCHSSQSAAAAAAAAAAALGSRGGGGGGGGGGG 423
Score = 31.2 bits (69), Expect = 3.4
Identities = 17/41 (41%), Positives = 21/41 (51%), Gaps = 1/41 (2%)
Query: 622 WASKGAAVGGGAGATAAGGGGGPGG-GGGGGPGGGGGPGGG 661
+A G+A G A+ +G G GG GG GG GG G G
Sbjct: 144 YAESGSAAGTTTSASGSGLGSLHGGSGGSGGSAALGGSGSG 184
Score = 30.0 bits (66), Expect = 7.5
Identities = 13/37 (35%), Positives = 15/37 (40%)
Query: 338 VACSGGAPGAGGAGGAGGAAAGAGAAGAGAGGPGGRG 374
++C A A A A G G G GG GG G
Sbjct: 390 LSCHSSQSAAAAAAAAAAALGSRGGGGGGGGGGGGGG 426
>gi|33620755 YEATS domain containing 2 [Homo sapiens]
Length = 1422
Score = 57.4 bits (137), Expect = 4e-08
Identities = 26/39 (66%), Positives = 29/39 (74%), Gaps = 3/39 (7%)
Query: 626 GAAVGGGAGATAAGGGGGPGGGGGGGPGGGGGPGGGGGS 664
G+A GG+GA GGGGG GGGGG G GGGG GGGGG+
Sbjct: 794 GSAASGGSGA---GGGGGGGGGGGSGSGGGGSTGGGGGT 829
Score = 49.7 bits (117), Expect = 9e-06
Identities = 22/42 (52%), Positives = 25/42 (59%)
Query: 623 ASKGAAVGGGAGATAAGGGGGPGGGGGGGPGGGGGPGGGGGS 664
+ A+ G GAG GGGGG G GGGG GGGG GGG+
Sbjct: 793 SGSAASGGSGAGGGGGGGGGGGSGSGGGGSTGGGGGTAGGGT 834
Score = 43.9 bits (102), Expect = 5e-04
Identities = 22/54 (40%), Positives = 28/54 (51%), Gaps = 4/54 (7%)
Query: 339 ACSGGAPGAGGAGGAGGAAAGAGAAGA--GAGGPGGRGEYEEL--GAVEQHVRY 388
A SGG+ GG GG GG +G+G G+ G GG G G G + QH+ Y
Sbjct: 796 AASGGSGAGGGGGGGGGGGSGSGGGGSTGGGGGTAGGGTQSTAGPGGISQHLTY 849
Score = 43.9 bits (102), Expect = 5e-04
Identities = 23/55 (41%), Positives = 27/55 (49%)
Query: 623 ASKGAAVGGGAGATAAGGGGGPGGGGGGGPGGGGGPGGGGGSLYSDVSTGLTWRS 677
AS G+ GGG G GG G GGG GG GG G G + +S LT+ S
Sbjct: 797 ASGGSGAGGGGGGGGGGGSGSGGGGSTGGGGGTAGGGTQSTAGPGGISQHLTYTS 851
Score = 38.5 bits (88), Expect = 0.021
Identities = 24/59 (40%), Positives = 27/59 (45%), Gaps = 1/59 (1%)
Query: 625 KGAAVGGGAGATAAGGGGGPGGGGGGGPGGGGGPGG-GGGSLYSDVSTGLTWRSGTASS 682
+GA + A G GG G GG GGGGG GG G G S G T GT S+
Sbjct: 779 QGAILRATNNANLQSGSAASGGSGAGGGGGGGGGGGSGSGGGGSTGGGGGTAGGGTQST 837
Score = 35.0 bits (79), Expect = 0.23
Identities = 23/59 (38%), Positives = 25/59 (42%), Gaps = 11/59 (18%)
Query: 173 GEQPPSGSGHGRPPGARPPHRGGGRGGGGGDAAAPPARGGGGGGKARPPGGGAAPCEPG 231
G GSG G GGG GGGGG + GGGGG A GG + PG
Sbjct: 794 GSAASGGSGAG---------GGGGGGGGGGSGSGGGGSTGGGGGTA--GGGTQSTAGPG 841
Score = 31.2 bits (69), Expect = 3.4
Identities = 16/44 (36%), Positives = 16/44 (36%)
Query: 350 AGGAGGAAAGAGAAGAGAGGPGGRGEYEELGAVEQHVRYETTGP 393
A G GA G G G G G GG G G T GP
Sbjct: 797 ASGGSGAGGGGGGGGGGGSGSGGGGSTGGGGGTAGGGTQSTAGP 840
Score = 29.6 bits (65), Expect = 9.8
Identities = 19/51 (37%), Positives = 19/51 (37%), Gaps = 7/51 (13%)
Query: 173 GEQPPSGSGHGRPPGARPPHRGGGRGGGGGDAAAPPARGGGGGGKARPPGG 223
G G G G G GG GGGGG A GGG PGG
Sbjct: 799 GGSGAGGGGGGGGGGGSGSGGGGSTGGGGGTA-------GGGTQSTAGPGG 842
>gi|116284398 WAS/WASL interacting protein family, member 1 [Homo
sapiens]
Length = 503
Score = 56.2 bits (134), Expect = 1e-07
Identities = 27/40 (67%), Positives = 27/40 (67%), Gaps = 1/40 (2%)
Query: 625 KGAAVGGGAGATAAGGG-GGPGGGGGGGPGGGGGPGGGGG 663
KGA GGG G GGG GG GGGGGGG GGGGP G GG
Sbjct: 63 KGAGAGGGGGGFGGGGGFGGGGGGGGGGSFGGGGPPGLGG 102
Score = 47.4 bits (111), Expect = 5e-05
Identities = 23/36 (63%), Positives = 23/36 (63%)
Query: 638 AGGGGGPGGGGGGGPGGGGGPGGGGGSLYSDVSTGL 673
AG GGG GG GGGG GGGG GGGGGS GL
Sbjct: 65 AGAGGGGGGFGGGGGFGGGGGGGGGGSFGGGGPPGL 100
Score = 40.0 bits (92), Expect = 0.007
Identities = 18/39 (46%), Positives = 19/39 (48%)
Query: 342 GGAPGAGGAGGAGGAAAGAGAAGAGAGGPGGRGEYEELG 380
GG G GG GG GG G G G GGP G G + G
Sbjct: 69 GGGGGFGGGGGFGGGGGGGGGGSFGGGGPPGLGGLFQAG 107
Score = 37.4 bits (85), Expect = 0.047
Identities = 21/44 (47%), Positives = 22/44 (50%), Gaps = 6/44 (13%)
Query: 184 RPPGARPPHRGGGRGGGGGDAAAPPARGGGGGGKARPPGGGAAP 227
+P GA GGG GGGGG GGGGGG GGG P
Sbjct: 61 KPKGAGAGGGGGGFGGGGGFG------GGGGGGGGGSFGGGGPP 98
Score = 36.6 bits (83), Expect = 0.080
Identities = 18/50 (36%), Positives = 24/50 (48%)
Query: 323 VSVGYLVRLVAGHEKVACSGGAPGAGGAGGAGGAAAGAGAAGAGAGGPGG 372
+S G ++ +++ A P GAGG GG G G G G GG GG
Sbjct: 40 ISKGKKLKKTVTNDRSAPILDKPKGAGAGGGGGGFGGGGGFGGGGGGGGG 89
Score = 35.4 bits (80), Expect = 0.18
Identities = 30/112 (26%), Positives = 36/112 (32%), Gaps = 29/112 (25%)
Query: 161 PSPPRRLPPPPP-----------------------------GEQPPSGSGHGRPPGARPP 191
P PP PPPPP G++ + R
Sbjct: 2 PVPPPPAPPPPPTFALANTEKPTLNKTEQAGRNALLSDISKGKKLKKTVTNDRSAPILDK 61
Query: 192 HRGGGRGGGGGDAAAPPARGGGGGGKARPPGGGAAPCEPGCQCRAPMVSVSS 243
+G G GGGGG GGGGGG GG P G +A M + S
Sbjct: 62 PKGAGAGGGGGGFGGGGGFGGGGGGGGGGSFGGGGPPGLGGLFQAGMPKLRS 113
Score = 35.4 bits (80), Expect = 0.18
Identities = 18/42 (42%), Positives = 19/42 (45%)
Query: 343 GAPGAGGAGGAGGAAAGAGAAGAGAGGPGGRGEYEELGAVEQ 384
GA GG GG GG G G G GG G G LG + Q
Sbjct: 64 GAGAGGGGGGFGGGGGFGGGGGGGGGGSFGGGGPPGLGGLFQ 105
Score = 32.7 bits (73), Expect = 1.2
Identities = 29/108 (26%), Positives = 37/108 (34%), Gaps = 21/108 (19%)
Query: 142 GNPDTLCMDYNRTDLTTAAPS-----------PPRRLPPPPPGEQPPSGSGHGRPPGARP 190
GN +T + L+++ P PP PPPP PP SG PP P
Sbjct: 327 GNDETPRLPQRNLSLSSSTPPLPSPGRSGPLPPPPSERPPPPVRDPPGRSGPLPPP--PP 384
Query: 191 PHRGGGRGGGGGDAAAPPARGGGGGGKARP--------PGGGAAPCEP 230
R G P+R G ++ P P GA P P
Sbjct: 385 VSRNGSTSRALPATPQLPSRSGVDSPRSGPRPPLPPDRPSAGAPPPPP 432
Score = 32.0 bits (71), Expect = 2.0
Identities = 24/78 (30%), Positives = 29/78 (37%), Gaps = 14/78 (17%)
Query: 157 TTAAPSPPRRLPPPPPGEQ-------PPSGSGHGRPPGARPPHRGGGRGGGGGDAAAPPA 209
+T PS + PPPPP PPS SG+ P R P R ++ PP
Sbjct: 296 STPRPSASSQAPPPPPPPSRPGPPPLPPSSSGNDETP--RLPQRNLSL-----SSSTPPL 348
Query: 210 RGGGGGGKARPPGGGAAP 227
G G PP P
Sbjct: 349 PSPGRSGPLPPPPSERPP 366
Score = 31.6 bits (70), Expect = 2.6
Identities = 30/106 (28%), Positives = 38/106 (35%), Gaps = 11/106 (10%)
Query: 161 PSPPRRL-----PPPPPGEQPPSGSGHGRPP----GARPPHRGGGRGGGGGDAAAPPARG 211
P+P R L PPPPP PS PP +PP R A PP
Sbjct: 254 PTPSRALDDKPPPPPPPVGNRPSIHREAVPPPPPQNNKPPVPSTPRPSASSQAPPPPPPP 313
Query: 212 GGGGGKARPPGGGAAPCEPGCQCRAPMVSVSSERHPLYNRVKTGQI 257
G PP P R +S+SS PL + ++G +
Sbjct: 314 SRPGPPPLPPSSSGNDETPRLPQR--NLSLSSSTPPLPSPGRSGPL 357
>gi|38373695 WAS/WASL interacting protein family, member 1 [Homo
sapiens]
Length = 503
Score = 56.2 bits (134), Expect = 1e-07
Identities = 27/40 (67%), Positives = 27/40 (67%), Gaps = 1/40 (2%)
Query: 625 KGAAVGGGAGATAAGGG-GGPGGGGGGGPGGGGGPGGGGG 663
KGA GGG G GGG GG GGGGGGG GGGGP G GG
Sbjct: 63 KGAGAGGGGGGFGGGGGFGGGGGGGGGGSFGGGGPPGLGG 102
Score = 47.4 bits (111), Expect = 5e-05
Identities = 23/36 (63%), Positives = 23/36 (63%)
Query: 638 AGGGGGPGGGGGGGPGGGGGPGGGGGSLYSDVSTGL 673
AG GGG GG GGGG GGGG GGGGGS GL
Sbjct: 65 AGAGGGGGGFGGGGGFGGGGGGGGGGSFGGGGPPGL 100
Score = 40.0 bits (92), Expect = 0.007
Identities = 18/39 (46%), Positives = 19/39 (48%)
Query: 342 GGAPGAGGAGGAGGAAAGAGAAGAGAGGPGGRGEYEELG 380
GG G GG GG GG G G G GGP G G + G
Sbjct: 69 GGGGGFGGGGGFGGGGGGGGGGSFGGGGPPGLGGLFQAG 107
Score = 37.4 bits (85), Expect = 0.047
Identities = 21/44 (47%), Positives = 22/44 (50%), Gaps = 6/44 (13%)
Query: 184 RPPGARPPHRGGGRGGGGGDAAAPPARGGGGGGKARPPGGGAAP 227
+P GA GGG GGGGG GGGGGG GGG P
Sbjct: 61 KPKGAGAGGGGGGFGGGGGFG------GGGGGGGGGSFGGGGPP 98
Score = 36.6 bits (83), Expect = 0.080
Identities = 18/50 (36%), Positives = 24/50 (48%)
Query: 323 VSVGYLVRLVAGHEKVACSGGAPGAGGAGGAGGAAAGAGAAGAGAGGPGG 372
+S G ++ +++ A P GAGG GG G G G G GG GG
Sbjct: 40 ISKGKKLKKTVTNDRSAPILDKPKGAGAGGGGGGFGGGGGFGGGGGGGGG 89
Score = 35.4 bits (80), Expect = 0.18
Identities = 30/112 (26%), Positives = 36/112 (32%), Gaps = 29/112 (25%)
Query: 161 PSPPRRLPPPPP-----------------------------GEQPPSGSGHGRPPGARPP 191
P PP PPPPP G++ + R
Sbjct: 2 PVPPPPAPPPPPTFALANTEKPTLNKTEQAGRNALLSDISKGKKLKKTVTNDRSAPILDK 61
Query: 192 HRGGGRGGGGGDAAAPPARGGGGGGKARPPGGGAAPCEPGCQCRAPMVSVSS 243
+G G GGGGG GGGGGG GG P G +A M + S
Sbjct: 62 PKGAGAGGGGGGFGGGGGFGGGGGGGGGGSFGGGGPPGLGGLFQAGMPKLRS 113
Score = 35.4 bits (80), Expect = 0.18
Identities = 18/42 (42%), Positives = 19/42 (45%)
Query: 343 GAPGAGGAGGAGGAAAGAGAAGAGAGGPGGRGEYEELGAVEQ 384
GA GG GG GG G G G GG G G LG + Q
Sbjct: 64 GAGAGGGGGGFGGGGGFGGGGGGGGGGSFGGGGPPGLGGLFQ 105
Score = 32.7 bits (73), Expect = 1.2
Identities = 29/108 (26%), Positives = 37/108 (34%), Gaps = 21/108 (19%)
Query: 142 GNPDTLCMDYNRTDLTTAAPS-----------PPRRLPPPPPGEQPPSGSGHGRPPGARP 190
GN +T + L+++ P PP PPPP PP SG PP P
Sbjct: 327 GNDETPRLPQRNLSLSSSTPPLPSPGRSGPLPPPPSERPPPPVRDPPGRSGPLPPP--PP 384
Query: 191 PHRGGGRGGGGGDAAAPPARGGGGGGKARP--------PGGGAAPCEP 230
R G P+R G ++ P P GA P P
Sbjct: 385 VSRNGSTSRALPATPQLPSRSGVDSPRSGPRPPLPPDRPSAGAPPPPP 432
Score = 32.0 bits (71), Expect = 2.0
Identities = 24/78 (30%), Positives = 29/78 (37%), Gaps = 14/78 (17%)
Query: 157 TTAAPSPPRRLPPPPPGEQ-------PPSGSGHGRPPGARPPHRGGGRGGGGGDAAAPPA 209
+T PS + PPPPP PPS SG+ P R P R ++ PP
Sbjct: 296 STPRPSASSQAPPPPPPPSRPGPPPLPPSSSGNDETP--RLPQRNLSL-----SSSTPPL 348
Query: 210 RGGGGGGKARPPGGGAAP 227
G G PP P
Sbjct: 349 PSPGRSGPLPPPPSERPP 366
Score = 31.6 bits (70), Expect = 2.6
Identities = 30/106 (28%), Positives = 38/106 (35%), Gaps = 11/106 (10%)
Query: 161 PSPPRRL-----PPPPPGEQPPSGSGHGRPP----GARPPHRGGGRGGGGGDAAAPPARG 211
P+P R L PPPPP PS PP +PP R A PP
Sbjct: 254 PTPSRALDDKPPPPPPPVGNRPSIHREAVPPPPPQNNKPPVPSTPRPSASSQAPPPPPPP 313
Query: 212 GGGGGKARPPGGGAAPCEPGCQCRAPMVSVSSERHPLYNRVKTGQI 257
G PP P R +S+SS PL + ++G +
Sbjct: 314 SRPGPPPLPPSSSGNDETPRLPQR--NLSLSSSTPPLPSPGRSGPL 357
>gi|4502565 calpain, small subunit 1 [Homo sapiens]
Length = 268
Score = 55.5 bits (132), Expect = 2e-07
Identities = 28/65 (43%), Positives = 34/65 (52%)
Query: 626 GAAVGGGAGATAAGGGGGPGGGGGGGPGGGGGPGGGGGSLYSDVSTGLTWRSGTASSVSY 685
G +GGG G G G GGGGGGG GGGGG GGGGG + G+ A++
Sbjct: 18 GGGLGGGLGNVLGGLISGAGGGGGGGGGGGGGGGGGGGGTAMRILGGVISAISEAAAQYN 77
Query: 686 PKQMP 690
P+ P
Sbjct: 78 PEPPP 82
Score = 49.7 bits (117), Expect = 9e-06
Identities = 25/45 (55%), Positives = 25/45 (55%), Gaps = 6/45 (13%)
Query: 625 KGAAVGGGAGATAAGGGGG------PGGGGGGGPGGGGGPGGGGG 663
KG GGG G GG G G GGGGG GGGGG GGGGG
Sbjct: 9 KGGGGGGGGGGGLGGGLGNVLGGLISGAGGGGGGGGGGGGGGGGG 53
Score = 38.5 bits (88), Expect = 0.021
Identities = 19/38 (50%), Positives = 20/38 (52%), Gaps = 5/38 (13%)
Query: 342 GGAPGAGGAGGA-----GGAAAGAGAAGAGAGGPGGRG 374
GG G GG GG GG +GAG G G GG GG G
Sbjct: 13 GGGGGGGGLGGGLGNVLGGLISGAGGGGGGGGGGGGGG 50
Score = 34.7 bits (78), Expect = 0.31
Identities = 27/72 (37%), Positives = 30/72 (41%), Gaps = 16/72 (22%)
Query: 179 GSGHGRPPGARPPHRGGGRGGGGGDAAAPPARGGGGGGKARPPGGGAAPCEPGCQCRAPM 238
G G G G GGG GGGGG GGGGGG GGG A + +
Sbjct: 22 GGGLGNVLGGLISGAGGGGGGGGGGG------GGGGGG-----GGGTA-----MRILGGV 65
Query: 239 VSVSSERHPLYN 250
+S SE YN
Sbjct: 66 ISAISEAAAQYN 77
Score = 33.9 bits (76), Expect = 0.52
Identities = 17/34 (50%), Positives = 18/34 (52%), Gaps = 1/34 (2%)
Query: 342 GGAPGAGGAGGAGGAAAGA-GAAGAGAGGPGGRG 374
GG G GG GG GG G +GAGG GG G
Sbjct: 10 GGGGGGGGGGGLGGGLGNVLGGLISGAGGGGGGG 43
Score = 32.7 bits (73), Expect = 1.2
Identities = 14/32 (43%), Positives = 17/32 (53%)
Query: 338 VACSGGAPGAGGAGGAGGAAAGAGAAGAGAGG 369
++ +GG G GG GG GG G G A GG
Sbjct: 33 ISGAGGGGGGGGGGGGGGGGGGGGTAMRILGG 64
>gi|51599151 calpain, small subunit 1 [Homo sapiens]
Length = 268
Score = 55.5 bits (132), Expect = 2e-07
Identities = 28/65 (43%), Positives = 34/65 (52%)
Query: 626 GAAVGGGAGATAAGGGGGPGGGGGGGPGGGGGPGGGGGSLYSDVSTGLTWRSGTASSVSY 685
G +GGG G G G GGGGGGG GGGGG GGGGG + G+ A++
Sbjct: 18 GGGLGGGLGNVLGGLISGAGGGGGGGGGGGGGGGGGGGGTAMRILGGVISAISEAAAQYN 77
Query: 686 PKQMP 690
P+ P
Sbjct: 78 PEPPP 82
Score = 49.7 bits (117), Expect = 9e-06
Identities = 25/45 (55%), Positives = 25/45 (55%), Gaps = 6/45 (13%)
Query: 625 KGAAVGGGAGATAAGGGGG------PGGGGGGGPGGGGGPGGGGG 663
KG GGG G GG G G GGGGG GGGGG GGGGG
Sbjct: 9 KGGGGGGGGGGGLGGGLGNVLGGLISGAGGGGGGGGGGGGGGGGG 53
Score = 38.5 bits (88), Expect = 0.021
Identities = 19/38 (50%), Positives = 20/38 (52%), Gaps = 5/38 (13%)
Query: 342 GGAPGAGGAGGA-----GGAAAGAGAAGAGAGGPGGRG 374
GG G GG GG GG +GAG G G GG GG G
Sbjct: 13 GGGGGGGGLGGGLGNVLGGLISGAGGGGGGGGGGGGGG 50
Score = 34.7 bits (78), Expect = 0.31
Identities = 27/72 (37%), Positives = 30/72 (41%), Gaps = 16/72 (22%)
Query: 179 GSGHGRPPGARPPHRGGGRGGGGGDAAAPPARGGGGGGKARPPGGGAAPCEPGCQCRAPM 238
G G G G GGG GGGGG GGGGGG GGG A + +
Sbjct: 22 GGGLGNVLGGLISGAGGGGGGGGGGG------GGGGGG-----GGGTA-----MRILGGV 65
Query: 239 VSVSSERHPLYN 250
+S SE YN
Sbjct: 66 ISAISEAAAQYN 77
Score = 33.9 bits (76), Expect = 0.52
Identities = 17/34 (50%), Positives = 18/34 (52%), Gaps = 1/34 (2%)
Query: 342 GGAPGAGGAGGAGGAAAGA-GAAGAGAGGPGGRG 374
GG G GG GG GG G +GAGG GG G
Sbjct: 10 GGGGGGGGGGGLGGGLGNVLGGLISGAGGGGGGG 43
Score = 32.7 bits (73), Expect = 1.2
Identities = 14/32 (43%), Positives = 17/32 (53%)
Query: 338 VACSGGAPGAGGAGGAGGAAAGAGAAGAGAGG 369
++ +GG G GG GG GG G G A GG
Sbjct: 33 ISGAGGGGGGGGGGGGGGGGGGGGTAMRILGG 64
>gi|109452587 family with sequence similarity 98, member B isoform 1
[Homo sapiens]
Length = 433
Score = 55.5 bits (132), Expect = 2e-07
Identities = 25/38 (65%), Positives = 25/38 (65%)
Query: 626 GAAVGGGAGATAAGGGGGPGGGGGGGPGGGGGPGGGGG 663
G GGG G GG GG GGG GGG GGGGG GGGGG
Sbjct: 344 GGGRGGGGGGGGRGGWGGGGGGWGGGGGGGGGWGGGGG 381
Score = 55.1 bits (131), Expect = 2e-07
Identities = 24/34 (70%), Positives = 24/34 (70%)
Query: 630 GGGAGATAAGGGGGPGGGGGGGPGGGGGPGGGGG 663
GGG G GGGGG GG GGGG G GGG GGGGG
Sbjct: 342 GGGGGRGGGGGGGGRGGWGGGGGGWGGGGGGGGG 375
Score = 53.5 bits (127), Expect = 6e-07
Identities = 24/38 (63%), Positives = 24/38 (63%)
Query: 626 GAAVGGGAGATAAGGGGGPGGGGGGGPGGGGGPGGGGG 663
G GGG G GGGG G GGGGG GGG G GGGGG
Sbjct: 346 GRGGGGGGGGRGGWGGGGGGWGGGGGGGGGWGGGGGGG 383
Score = 53.1 bits (126), Expect = 8e-07
Identities = 24/38 (63%), Positives = 24/38 (63%)
Query: 626 GAAVGGGAGATAAGGGGGPGGGGGGGPGGGGGPGGGGG 663
G GGG G GGGG GGGGGGG GGGG GG GG
Sbjct: 349 GGGGGGGRGGWGGGGGGWGGGGGGGGGWGGGGGGGRGG 386
Score = 52.8 bits (125), Expect = 1e-06
Identities = 26/47 (55%), Positives = 27/47 (57%), Gaps = 5/47 (10%)
Query: 622 WASKGAAVGGGAGATAAGGGGGPGGGGGGG-----PGGGGGPGGGGG 663
W + GG G GGGGG GGGGGGG GGGGG GGGGG
Sbjct: 325 WQKRQEGGGGRGGWGGGGGGGGRGGGGGGGGRGGWGGGGGGWGGGGG 371
Score = 52.8 bits (125), Expect = 1e-06
Identities = 24/39 (61%), Positives = 25/39 (64%)
Query: 625 KGAAVGGGAGATAAGGGGGPGGGGGGGPGGGGGPGGGGG 663
+G GGG G GGGGG G GG GG GGG G GGGGG
Sbjct: 335 RGGWGGGGGGGGRGGGGGGGGRGGWGGGGGGWGGGGGGG 373
Score = 52.8 bits (125), Expect = 1e-06
Identities = 23/34 (67%), Positives = 23/34 (67%)
Query: 630 GGGAGATAAGGGGGPGGGGGGGPGGGGGPGGGGG 663
GGG G GGGGG GG GGG GG GG GGGGG
Sbjct: 341 GGGGGGRGGGGGGGGRGGWGGGGGGWGGGGGGGG 374
Score = 52.8 bits (125), Expect = 1e-06
Identities = 24/38 (63%), Positives = 24/38 (63%)
Query: 626 GAAVGGGAGATAAGGGGGPGGGGGGGPGGGGGPGGGGG 663
G GGG G G GGG GG GGGG GGGG GGGGG
Sbjct: 345 GGRGGGGGGGGRGGWGGGGGGWGGGGGGGGGWGGGGGG 382
Score = 52.4 bits (124), Expect = 1e-06
Identities = 24/39 (61%), Positives = 25/39 (64%)
Query: 625 KGAAVGGGAGATAAGGGGGPGGGGGGGPGGGGGPGGGGG 663
+G GGG GGGGG GGGGGGG G GGG GGG G
Sbjct: 347 RGGGGGGGGRGGWGGGGGGWGGGGGGGGGWGGGGGGGRG 385
Score = 52.0 bits (123), Expect = 2e-06
Identities = 27/49 (55%), Positives = 27/49 (55%), Gaps = 1/49 (2%)
Query: 630 GGGAGATAAGGGGGPGGGGGGGPGGGGGPGGGGGSLYSDVSTGLTWRSG 678
GGG G GGGGG G GGGGG GG GG GGGGG G W G
Sbjct: 332 GGGRGGWGGGGGGG-GRGGGGGGGGRGGWGGGGGGWGGGGGGGGGWGGG 379
Score = 50.8 bits (120), Expect = 4e-06
Identities = 23/42 (54%), Positives = 23/42 (54%)
Query: 622 WASKGAAVGGGAGATAAGGGGGPGGGGGGGPGGGGGPGGGGG 663
W G G G G G GG GGGGG G GGGGG G GGG
Sbjct: 338 WGGGGGGGGRGGGGGGGGRGGWGGGGGGWGGGGGGGGGWGGG 379
Score = 49.3 bits (116), Expect = 1e-05
Identities = 26/54 (48%), Positives = 26/54 (48%), Gaps = 7/54 (12%)
Query: 622 WASKGAAVGGGAGATAAGGGGGPGGGGG-------GGPGGGGGPGGGGGSLYSD 668
W G GGG G GGGG GG GG GG GG GG GG GG Y D
Sbjct: 359 WGGGGGGWGGGGGGGGGWGGGGGGGRGGFQGRGDYGGRGGYGGRGGYGGRGYGD 412
Score = 45.1 bits (105), Expect = 2e-04
Identities = 22/39 (56%), Positives = 22/39 (56%)
Query: 640 GGGGPGGGGGGGPGGGGGPGGGGGSLYSDVSTGLTWRSG 678
GGGG GG GGGG GGG G GGGGG G W G
Sbjct: 331 GGGGRGGWGGGGGGGGRGGGGGGGGRGGWGGGGGGWGGG 369
Score = 43.9 bits (102), Expect = 5e-04
Identities = 25/62 (40%), Positives = 28/62 (45%), Gaps = 11/62 (17%)
Query: 164 PRRLPPPPPGEQPPSGSGHGRPPGARPPHRGGGRGG-GGGDAAAPPARGGGGGGKARPPG 222
P + PPPP PP + GGGRGG GGG GGGGGG+ G
Sbjct: 312 PNEIEPPPPE----------MPPWQKRQEGGGGRGGWGGGGGGGGRGGGGGGGGRGGWGG 361
Query: 223 GG 224
GG
Sbjct: 362 GG 363
Score = 43.1 bits (100), Expect = 9e-04
Identities = 22/38 (57%), Positives = 22/38 (57%), Gaps = 1/38 (2%)
Query: 626 GAAVGGGAGATAAGGGGGPGGGGGGGPGGGGGPGGGGG 663
G GG G GGGG GGGG GG GGGGG GG G
Sbjct: 353 GGGRGGWGGGGGGWGGGGGGGGGWGG-GGGGGRGGFQG 389
Score = 43.1 bits (100), Expect = 9e-04
Identities = 23/40 (57%), Positives = 23/40 (57%), Gaps = 3/40 (7%)
Query: 630 GGGAGATAAGGGGGPGGG---GGGGPGGGGGPGGGGGSLY 666
GG G GG GG G G GGGG GGGGG GGGG Y
Sbjct: 394 GGRGGYGGRGGYGGRGYGDPYGGGGGGGGGGGGGGGYRRY 433
Score = 42.4 bits (98), Expect = 0.001
Identities = 24/48 (50%), Positives = 24/48 (50%), Gaps = 10/48 (20%)
Query: 626 GAAVGGGAGATAAGGGGGPGGGGG----------GGPGGGGGPGGGGG 663
G GG G GG GG GG GG GG GGGGG GGGGG
Sbjct: 381 GGGRGGFQGRGDYGGRGGYGGRGGYGGRGYGDPYGGGGGGGGGGGGGG 428
Score = 41.2 bits (95), Expect = 0.003
Identities = 18/39 (46%), Positives = 20/39 (51%)
Query: 342 GGAPGAGGAGGAGGAAAGAGAAGAGAGGPGGRGEYEELG 380
GG G G GG G G G G G GG GGRG ++ G
Sbjct: 353 GGGRGGWGGGGGGWGGGGGGGGGWGGGGGGGRGGFQGRG 391
Score = 40.4 bits (93), Expect = 0.006
Identities = 18/33 (54%), Positives = 18/33 (54%)
Query: 342 GGAPGAGGAGGAGGAAAGAGAAGAGAGGPGGRG 374
GG G GG GG GG G G G G GG GG G
Sbjct: 345 GGRGGGGGGGGRGGWGGGGGGWGGGGGGGGGWG 377
Score = 40.4 bits (93), Expect = 0.006
Identities = 18/33 (54%), Positives = 18/33 (54%)
Query: 342 GGAPGAGGAGGAGGAAAGAGAAGAGAGGPGGRG 374
GG G GG GG GG G G G G GG GG G
Sbjct: 348 GGGGGGGGRGGWGGGGGGWGGGGGGGGGWGGGG 380
Score = 38.5 bits (88), Expect = 0.021
Identities = 17/33 (51%), Positives = 17/33 (51%)
Query: 342 GGAPGAGGAGGAGGAAAGAGAAGAGAGGPGGRG 374
GG G GG GG GG G G G G G GG G
Sbjct: 333 GGRGGWGGGGGGGGRGGGGGGGGRGGWGGGGGG 365
Score = 38.1 bits (87), Expect = 0.028
Identities = 17/33 (51%), Positives = 17/33 (51%)
Query: 342 GGAPGAGGAGGAGGAAAGAGAAGAGAGGPGGRG 374
GG G G GG GG G G G G GG GG G
Sbjct: 341 GGGGGGRGGGGGGGGRGGWGGGGGGWGGGGGGG 373
Score = 37.7 bits (86), Expect = 0.036
Identities = 17/33 (51%), Positives = 17/33 (51%)
Query: 342 GGAPGAGGAGGAGGAAAGAGAAGAGAGGPGGRG 374
GG G GG GG GG G G G G GG G G
Sbjct: 336 GGWGGGGGGGGRGGGGGGGGRGGWGGGGGGWGG 368
Score = 37.4 bits (85), Expect = 0.047
Identities = 20/45 (44%), Positives = 20/45 (44%), Gaps = 10/45 (22%)
Query: 342 GGAPGAGGAGGAGGAAAGAGAAGAGA----------GGPGGRGEY 376
GG G GG GG GG G G G G GG GGRG Y
Sbjct: 361 GGGGGWGGGGGGGGGWGGGGGGGRGGFQGRGDYGGRGGYGGRGGY 405
Score = 37.0 bits (84), Expect = 0.062
Identities = 16/30 (53%), Positives = 18/30 (60%)
Query: 622 WASKGAAVGGGAGATAAGGGGGPGGGGGGG 651
+ +G G G G GGGGG GGGGGGG
Sbjct: 399 YGGRGGYGGRGYGDPYGGGGGGGGGGGGGG 428
Score = 36.2 bits (82), Expect = 0.11
Identities = 16/33 (48%), Positives = 16/33 (48%)
Query: 342 GGAPGAGGAGGAGGAAAGAGAAGAGAGGPGGRG 374
GG G GG GG G G G G GG GG G
Sbjct: 331 GGGGRGGWGGGGGGGGRGGGGGGGGRGGWGGGG 363
Score = 36.2 bits (82), Expect = 0.11
Identities = 17/30 (56%), Positives = 17/30 (56%)
Query: 195 GGRGGGGGDAAAPPARGGGGGGKARPPGGG 224
GGRGG GG P GGGGGG GGG
Sbjct: 400 GGRGGYGGRGYGDPYGGGGGGGGGGGGGGG 429
Score = 35.8 bits (81), Expect = 0.14
Identities = 17/33 (51%), Positives = 17/33 (51%)
Query: 342 GGAPGAGGAGGAGGAAAGAGAAGAGAGGPGGRG 374
GG G GG GG GG G G G GG GG G
Sbjct: 394 GGRGGYGGRGGYGGRGYGDPYGGGGGGGGGGGG 426
Score = 33.9 bits (76), Expect = 0.52
Identities = 17/34 (50%), Positives = 17/34 (50%), Gaps = 1/34 (2%)
Query: 342 GGAPGAGGAG-GAGGAAAGAGAAGAGAGGPGGRG 374
G G GG G G GG G G G G GG GG G
Sbjct: 337 GWGGGGGGGGRGGGGGGGGRGGWGGGGGGWGGGG 370
Score = 31.2 bits (69), Expect = 3.4
Identities = 19/41 (46%), Positives = 20/41 (48%), Gaps = 15/41 (36%)
Query: 179 GSGHGRPPGARPPHRGGGRGGGGGDAAAPPARGGGGGGKAR 219
G G+G P GGG GGGGG GGGGGG R
Sbjct: 407 GRGYGDP-------YGGGGGGGGG--------GGGGGGYRR 432
Score = 30.8 bits (68), Expect = 4.4
Identities = 15/33 (45%), Positives = 15/33 (45%)
Query: 342 GGAPGAGGAGGAGGAAAGAGAAGAGAGGPGGRG 374
GG G G GG GG G G G G P G G
Sbjct: 385 GGFQGRGDYGGRGGYGGRGGYGGRGYGDPYGGG 417
Score = 30.8 bits (68), Expect = 4.4
Identities = 17/40 (42%), Positives = 17/40 (42%), Gaps = 5/40 (12%)
Query: 342 GGAPGAGGAGGAGGAAAGA-----GAAGAGAGGPGGRGEY 376
G G GG GG GG G G G GG GG G Y
Sbjct: 391 GDYGGRGGYGGRGGYGGRGYGDPYGGGGGGGGGGGGGGGY 430
>gi|5032007 purine-rich element binding protein A [Homo sapiens]
Length = 322
Score = 55.1 bits (131), Expect = 2e-07
Identities = 24/39 (61%), Positives = 26/39 (66%)
Query: 626 GAAVGGGAGATAAGGGGGPGGGGGGGPGGGGGPGGGGGS 664
GAA+G G G G G GGGGGGG GGGG GGGGG+
Sbjct: 12 GAALGSGGSLGHPGSGSGSGGGGGGGGGGGGSGGGGGGA 50
Score = 48.1 bits (113), Expect = 3e-05
Identities = 20/36 (55%), Positives = 24/36 (66%)
Query: 626 GAAVGGGAGATAAGGGGGPGGGGGGGPGGGGGPGGG 661
G ++G + +GGGGG GGGGGG GGGGG GG
Sbjct: 18 GGSLGHPGSGSGSGGGGGGGGGGGGSGGGGGGAPGG 53
Score = 43.5 bits (101), Expect = 7e-04
Identities = 21/34 (61%), Positives = 22/34 (64%), Gaps = 1/34 (2%)
Query: 631 GGAGATAAGGGGGPGGGGGGGPGGGGGPGGGGGS 664
GGA + G G PG G G G GGGGG GGGGGS
Sbjct: 11 GGAALGSGGSLGHPGSGSGSGGGGGGG-GGGGGS 43
Score = 39.7 bits (91), Expect = 0.010
Identities = 18/34 (52%), Positives = 18/34 (52%)
Query: 630 GGGAGATAAGGGGGPGGGGGGGPGGGGGPGGGGG 663
G G A G GG G G G GGGG GGGGG
Sbjct: 7 GSEQGGAALGSGGSLGHPGSGSGSGGGGGGGGGG 40
Score = 38.9 bits (89), Expect = 0.016
Identities = 17/37 (45%), Positives = 22/37 (59%), Gaps = 1/37 (2%)
Query: 346 GAGGAGGAGGAAAGAGAAGAGAGGPGG-RGEYEELGA 381
G+G GG GG G G+ G G G PGG + E +EL +
Sbjct: 27 GSGSGGGGGGGGGGGGSGGGGGGAPGGLQHETQELAS 63
Score = 37.4 bits (85), Expect = 0.047
Identities = 16/33 (48%), Positives = 21/33 (63%)
Query: 342 GGAPGAGGAGGAGGAAAGAGAAGAGAGGPGGRG 374
G A G+GG+ G G+ +G+G G G GG GG G
Sbjct: 12 GAALGSGGSLGHPGSGSGSGGGGGGGGGGGGSG 44
Score = 36.2 bits (82), Expect = 0.11
Identities = 15/32 (46%), Positives = 18/32 (56%)
Query: 341 SGGAPGAGGAGGAGGAAAGAGAAGAGAGGPGG 372
SGG+ G G+G G G G G G+GG GG
Sbjct: 17 SGGSLGHPGSGSGSGGGGGGGGGGGGSGGGGG 48
Score = 35.8 bits (81), Expect = 0.14
Identities = 16/42 (38%), Positives = 23/42 (54%)
Query: 333 AGHEKVACSGGAPGAGGAGGAGGAAAGAGAAGAGAGGPGGRG 374
+G E+ + G+ G+ G G+G + G G G G GG GG G
Sbjct: 6 SGSEQGGAALGSGGSLGHPGSGSGSGGGGGGGGGGGGSGGGG 47
Score = 35.8 bits (81), Expect = 0.14
Identities = 23/54 (42%), Positives = 24/54 (44%), Gaps = 11/54 (20%)
Query: 174 EQPPSGSGHGRPPGARPPHRGGGRGGGGGDAAAPPARGGGGGGKARPPGGGAAP 227
EQ + G G G H G G G GGG GGGGGG GGG AP
Sbjct: 9 EQGGAALGSGGSLG----HPGSGSGSGGGG-------GGGGGGGGSGGGGGGAP 51
Score = 33.5 bits (75), Expect = 0.68
Identities = 16/48 (33%), Positives = 22/48 (45%)
Query: 343 GAPGAGGAGGAGGAAAGAGAAGAGAGGPGGRGEYEELGAVEQHVRYET 390
G G G G +G+G+ G G GG GG G G +++ET
Sbjct: 11 GGAALGSGGSLGHPGSGSGSGGGGGGGGGGGGSGGGGGGAPGGLQHET 58
Score = 32.0 bits (71), Expect = 2.0
Identities = 13/28 (46%), Positives = 15/28 (53%)
Query: 623 ASKGAAVGGGAGATAAGGGGGPGGGGGG 650
+ G+ GGG G G GGG GG GG
Sbjct: 26 SGSGSGGGGGGGGGGGGSGGGGGGAPGG 53
Score = 31.2 bits (69), Expect = 3.4
Identities = 22/52 (42%), Positives = 22/52 (42%), Gaps = 22/52 (42%)
Query: 172 PGEQPPSGSGHGRPPGARPPHRGGGRGGGGGDAAAPPARGGGGGGKARPPGG 223
PG SG G GGG GGGGG GGGGGG PGG
Sbjct: 24 PGSGSGSGGG------------GGGGGGGGGS-------GGGGGG---APGG 53
Score = 30.4 bits (67), Expect = 5.8
Identities = 17/42 (40%), Positives = 19/42 (45%)
Query: 607 GKTLESWRSLCTRCCWASKGAAVGGGAGATAAGGGGGPGGGG 648
G L S SL + G GGG G +GGGGG GG
Sbjct: 12 GAALGSGGSLGHPGSGSGSGGGGGGGGGGGGSGGGGGGAPGG 53
>gi|22547197 zinc finger protein of the cerebellum 2 [Homo sapiens]
Length = 532
Score = 55.1 bits (131), Expect = 2e-07
Identities = 25/45 (55%), Positives = 28/45 (62%)
Query: 624 SKGAAVGGGAGATAAGGGGGPGGGGGGGPGGGGGPGGGGGSLYSD 668
S GA G G G+ + GGGGG GGGGGG GGG G GG L S+
Sbjct: 482 SGGAGGGSGGGSGSGGGGGGAGGGGGGSSGGGSGTAGGHSGLSSN 526
Score = 52.8 bits (125), Expect = 1e-06
Identities = 24/42 (57%), Positives = 28/42 (66%)
Query: 623 ASKGAAVGGGAGATAAGGGGGPGGGGGGGPGGGGGPGGGGGS 664
A+ +AV G G+ + G GGG GGG G G GGGG GGGGGS
Sbjct: 468 AAAVSAVHRGGGSGSGGAGGGSGGGSGSGGGGGGAGGGGGGS 509
Score = 52.0 bits (123), Expect = 2e-06
Identities = 22/39 (56%), Positives = 25/39 (64%)
Query: 626 GAAVGGGAGATAAGGGGGPGGGGGGGPGGGGGPGGGGGS 664
G + GGAG + GG G GGGGG G GGGG GGG G+
Sbjct: 478 GGSGSGGAGGGSGGGSGSGGGGGGAGGGGGGSSGGGSGT 516
Score = 51.6 bits (122), Expect = 2e-06
Identities = 26/48 (54%), Positives = 31/48 (64%), Gaps = 3/48 (6%)
Query: 630 GGGAGATAAGGGGGPGGGGGGGPGGGGGPGG---GGGSLYSDVSTGLT 674
GGG+G+ AGGG G G G GGG GG GG GG GGGS + +GL+
Sbjct: 477 GGGSGSGGAGGGSGGGSGSGGGGGGAGGGGGGSSGGGSGTAGGHSGLS 524
Score = 51.2 bits (121), Expect = 3e-06
Identities = 21/38 (55%), Positives = 23/38 (60%)
Query: 625 KGAAVGGGAGATAAGGGGGPGGGGGGGPGGGGGPGGGG 662
+G G G +GGG G GGGGGG GGGGG GGG
Sbjct: 476 RGGGSGSGGAGGGSGGGSGSGGGGGGAGGGGGGSSGGG 513
Score = 50.4 bits (119), Expect = 5e-06
Identities = 22/42 (52%), Positives = 25/42 (59%)
Query: 623 ASKGAAVGGGAGATAAGGGGGPGGGGGGGPGGGGGPGGGGGS 664
+ G A GG G + +GGGGG GGGGGG GGG GG S
Sbjct: 480 SGSGGAGGGSGGGSGSGGGGGGAGGGGGGSSGGGSGTAGGHS 521
Score = 47.8 bits (112), Expect = 3e-05
Identities = 28/63 (44%), Positives = 30/63 (47%), Gaps = 1/63 (1%)
Query: 623 ASKGAAVGGGAGATAAGGGGGPGGGG-GGGPGGGGGPGGGGGSLYSDVSTGLTWRSGTAS 681
A+ AA A +A GGG G GG GGG GGG G GGGGG SGTA
Sbjct: 459 AAAAAAAAAAAAVSAVHRGGGSGSGGAGGGSGGGSGSGGGGGGAGGGGGGSSGGGSGTAG 518
Query: 682 SVS 684
S
Sbjct: 519 GHS 521
Score = 44.7 bits (104), Expect = 3e-04
Identities = 18/31 (58%), Positives = 21/31 (67%)
Query: 342 GGAPGAGGAGGAGGAAAGAGAAGAGAGGPGG 372
GG G+GGAGG G +G+G G GAGG GG
Sbjct: 477 GGGSGSGGAGGGSGGGSGSGGGGGGAGGGGG 507
Score = 38.9 bits (89), Expect = 0.016
Identities = 16/34 (47%), Positives = 18/34 (52%)
Query: 341 SGGAPGAGGAGGAGGAAAGAGAAGAGAGGPGGRG 374
SG GG+GG G+ G G AG G GG G G
Sbjct: 480 SGSGGAGGGSGGGSGSGGGGGGAGGGGGGSSGGG 513
Score = 38.5 bits (88), Expect = 0.021
Identities = 15/29 (51%), Positives = 18/29 (62%)
Query: 346 GAGGAGGAGGAAAGAGAAGAGAGGPGGRG 374
G G+GGAGG + G +G G GG GG G
Sbjct: 478 GGSGSGGAGGGSGGGSGSGGGGGGAGGGG 506
Score = 38.5 bits (88), Expect = 0.021
Identities = 16/41 (39%), Positives = 20/41 (48%)
Query: 341 SGGAPGAGGAGGAGGAAAGAGAAGAGAGGPGGRGEYEELGA 381
+GG G G G GG AG G G+ GG G G + L +
Sbjct: 485 AGGGSGGGSGSGGGGGGAGGGGGGSSGGGSGTAGGHSGLSS 525
Score = 38.1 bits (87), Expect = 0.028
Identities = 19/38 (50%), Positives = 19/38 (50%)
Query: 627 AAVGGGAGATAAGGGGGPGGGGGGGPGGGGGPGGGGGS 664
AA A A AA GGG G G GGG GGG GS
Sbjct: 458 AAAAAAAAAAAAAVSAVHRGGGSGSGGAGGGSGGGSGS 495
Score = 37.4 bits (85), Expect = 0.047
Identities = 16/35 (45%), Positives = 18/35 (51%)
Query: 192 HRGGGRGGGGGDAAAPPARGGGGGGKARPPGGGAA 226
HRGGG G GG + G GGGG GGG +
Sbjct: 475 HRGGGSGSGGAGGGSGGGSGSGGGGGGAGGGGGGS 509
Score = 37.0 bits (84), Expect = 0.062
Identities = 18/41 (43%), Positives = 19/41 (46%)
Query: 623 ASKGAAVGGGAGATAAGGGGGPGGGGGGGPGGGGGPGGGGG 663
A+ AA A A A GG G GG GGG G G G G
Sbjct: 456 AAAAAAAAAAAAAAAVSAVHRGGGSGSGGAGGGSGGGSGSG 496
Score = 35.0 bits (79), Expect = 0.23
Identities = 22/47 (46%), Positives = 24/47 (51%), Gaps = 11/47 (23%)
Query: 179 GSGHGRPPGARPPHRGGGRGGGGGDAAAPPARGGGGGGKARPPGGGA 225
GSG G GA GGG GGG G GGGGGG + GGG+
Sbjct: 479 GSGSG---GA-----GGGSGGGSGSGGGGGGAGGGGGGSS---GGGS 514
Score = 33.9 bits (76), Expect = 0.52
Identities = 15/36 (41%), Positives = 18/36 (50%)
Query: 339 ACSGGAPGAGGAGGAGGAAAGAGAAGAGAGGPGGRG 374
A + A GG G+GGA G+G GG GG G
Sbjct: 468 AAAVSAVHRGGGSGSGGAGGGSGGGSGSGGGGGGAG 503
Score = 33.9 bits (76), Expect = 0.52
Identities = 14/34 (41%), Positives = 16/34 (47%)
Query: 339 ACSGGAPGAGGAGGAGGAAAGAGAAGAGAGGPGG 372
A G G+G GG GGA G G + G G G
Sbjct: 485 AGGGSGGGSGSGGGGGGAGGGGGGSSGGGSGTAG 518
Score = 31.6 bits (70), Expect = 2.6
Identities = 15/41 (36%), Positives = 19/41 (46%), Gaps = 3/41 (7%)
Query: 341 SGGAPGAGGAG---GAGGAAAGAGAAGAGAGGPGGRGEYEE 378
SGG G+GG G G GG + G +G G G + E
Sbjct: 489 SGGGSGSGGGGGGAGGGGGGSSGGGSGTAGGHSGLSSNFNE 529
Score = 31.2 bits (69), Expect = 3.4
Identities = 18/46 (39%), Positives = 22/46 (47%), Gaps = 6/46 (13%)
Query: 173 GEQPPSGSGHGRPPGARPPHRGGGRGGGGGDAAAPPARGGGGGGKA 218
G G+G G G+ GGG GGGGG ++ GGG G A
Sbjct: 478 GGSGSGGAGGGSGGGSGSGGGGGGAGGGGGGSS------GGGSGTA 517
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.321 0.140 0.462
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 35,076,331
Number of Sequences: 37866
Number of extensions: 2339942
Number of successful extensions: 86913
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 1043
Number of HSP's successfully gapped in prelim test: 948
Number of HSP's that attempted gapping in prelim test: 24617
Number of HSP's gapped (non-prelim): 39703
length of query: 694
length of database: 18,247,518
effective HSP length: 109
effective length of query: 585
effective length of database: 14,120,124
effective search space: 8260272540
effective search space used: 8260272540
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.