Guide to the Human Genome
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Search of human proteins with 7662346

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|7662346 ADNP homeobox 2 [Homo sapiens]
         (1131 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|7662346 ADNP homeobox 2 [Homo sapiens]                            2305   0.0  
gi|31563503 activity-dependent neuroprotector [Homo sapiens]          249   8e-66
gi|12229217 activity-dependent neuroprotector [Homo sapiens]          249   8e-66
gi|33286442 BCL6 co-repressor-like 1 [Homo sapiens]                    75   4e-13
gi|32455273 WNK lysine deficient protein kinase 2 [Homo sapiens]       74   8e-13
gi|126090892 aggrecan isoform 2 precursor [Homo sapiens]               69   2e-11
gi|126090883 aggrecan isoform 1 precursor [Homo sapiens]               69   2e-11
gi|146219843 Snf2-related CBP activator protein [Homo sapiens]         69   2e-11
gi|160707881 formin 2 [Homo sapiens]                                   67   1e-10
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi...    65   4e-10
gi|163965366 nascent polypeptide-associated complex alpha subuni...    65   5e-10
gi|98986457 host cell factor 1 [Homo sapiens]                          61   5e-09
gi|239749951 PREDICTED: similar to mucin 2 [Homo sapiens]              60   1e-08
gi|46397392 pogo transposable element with ZNF domain isoform 3 ...    60   2e-08
gi|46397390 pogo transposable element with ZNF domain isoform 1 ...    60   2e-08
gi|46397394 pogo transposable element with ZNF domain isoform 2 ...    60   2e-08
gi|19924099 synapsin I isoform Ia [Homo sapiens]                       60   2e-08
gi|46852161 methyl-CpG binding domain protein 6 [Homo sapiens]         59   2e-08
gi|116284392 mucin 2 precursor [Homo sapiens]                          59   3e-08
gi|163914392 glioma tumor suppressor candidate region gene 1 [Ho...    58   4e-08
gi|171460948 TSC22 domain family, member 1 isoform 1 [Homo sapiens]    58   6e-08
gi|4508017 zinc finger protein 207 isoform a [Homo sapiens]            57   1e-07
gi|150378545 POM121 membrane glycoprotein (rat)-like [Homo sapiens]    56   2e-07
gi|4885407 hyperpolarization activated cyclic nucleotide-gated p...    55   3e-07
gi|239752280 PREDICTED: similar to family with sequence similari...    55   4e-07
gi|19924097 synapsin I isoform Ib [Homo sapiens]                       55   4e-07
gi|7662236 TSC22 domain family, member 2 [Homo sapiens]                55   4e-07
gi|210032463 family with sequence similarity 48, member B2 [Homo...    55   4e-07
gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi...    54   6e-07
gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi...    54   6e-07

>gi|7662346 ADNP homeobox 2 [Homo sapiens]
          Length = 1131

 Score = 2305 bits (5972), Expect = 0.0
 Identities = 1131/1131 (100%), Positives = 1131/1131 (100%)

Query: 1    MFQIPVENLDNIRKVRKKVKGILVDIGLDSCKELLKDLKGFDPGEKYFHNTSWGDVSLWE 60
            MFQIPVENLDNIRKVRKKVKGILVDIGLDSCKELLKDLKGFDPGEKYFHNTSWGDVSLWE
Sbjct: 1    MFQIPVENLDNIRKVRKKVKGILVDIGLDSCKELLKDLKGFDPGEKYFHNTSWGDVSLWE 60

Query: 61   PSGKKVRYRTKPYCCGLCKYSTKVLTSFKNHLHRYHEDEIDQELVIPCPNCVFASQPKVV 120
            PSGKKVRYRTKPYCCGLCKYSTKVLTSFKNHLHRYHEDEIDQELVIPCPNCVFASQPKVV
Sbjct: 61   PSGKKVRYRTKPYCCGLCKYSTKVLTSFKNHLHRYHEDEIDQELVIPCPNCVFASQPKVV 120

Query: 121  GRHFRMFHAPVRKVQNYTVNILGETKSSRSDVISFTCLKCNFSNTLYYSMKKHVLVAHFH 180
            GRHFRMFHAPVRKVQNYTVNILGETKSSRSDVISFTCLKCNFSNTLYYSMKKHVLVAHFH
Sbjct: 121  GRHFRMFHAPVRKVQNYTVNILGETKSSRSDVISFTCLKCNFSNTLYYSMKKHVLVAHFH 180

Query: 181  YLINSYFGLRTEEMGEQPKTNDTVSIEKIPPPDKYYCKKCNANASSQDALMYHILTSDIH 240
            YLINSYFGLRTEEMGEQPKTNDTVSIEKIPPPDKYYCKKCNANASSQDALMYHILTSDIH
Sbjct: 181  YLINSYFGLRTEEMGEQPKTNDTVSIEKIPPPDKYYCKKCNANASSQDALMYHILTSDIH 240

Query: 241  RDLENKLRSVISEHIKRTGLLKQTHIAPKPAAHLAAPANGSAPSAPAQPPCFHLALPQNS 300
            RDLENKLRSVISEHIKRTGLLKQTHIAPKPAAHLAAPANGSAPSAPAQPPCFHLALPQNS
Sbjct: 241  RDLENKLRSVISEHIKRTGLLKQTHIAPKPAAHLAAPANGSAPSAPAQPPCFHLALPQNS 300

Query: 301  PSPAAGQPVTVAQGAPGSLTHSPPAAGQSHMTLVSSPLPVGQNSLTLQPPAPQPVFLSHG 360
            PSPAAGQPVTVAQGAPGSLTHSPPAAGQSHMTLVSSPLPVGQNSLTLQPPAPQPVFLSHG
Sbjct: 301  PSPAAGQPVTVAQGAPGSLTHSPPAAGQSHMTLVSSPLPVGQNSLTLQPPAPQPVFLSHG 360

Query: 361  VPLHQSVNPPVLPLSQPVGPVNKSVGTSVLPINQTVRPGVLPLTQPVGPINRPVGPGVLP 420
            VPLHQSVNPPVLPLSQPVGPVNKSVGTSVLPINQTVRPGVLPLTQPVGPINRPVGPGVLP
Sbjct: 361  VPLHQSVNPPVLPLSQPVGPVNKSVGTSVLPINQTVRPGVLPLTQPVGPINRPVGPGVLP 420

Query: 421  VSPSVTPGVLQAVSPGVLSVSRAVPSGVLPAGQMTPAGQMTPAGVIPGQTATSGVLPTGQ 480
            VSPSVTPGVLQAVSPGVLSVSRAVPSGVLPAGQMTPAGQMTPAGVIPGQTATSGVLPTGQ
Sbjct: 421  VSPSVTPGVLQAVSPGVLSVSRAVPSGVLPAGQMTPAGQMTPAGVIPGQTATSGVLPTGQ 480

Query: 481  MVQSGVLPVGQTAPSRVLPPGQTAPLRVISAGQVVPSGLLSPNQTVSSSAVVPVNQGVNS 540
            MVQSGVLPVGQTAPSRVLPPGQTAPLRVISAGQVVPSGLLSPNQTVSSSAVVPVNQGVNS
Sbjct: 481  MVQSGVLPVGQTAPSRVLPPGQTAPLRVISAGQVVPSGLLSPNQTVSSSAVVPVNQGVNS 540

Query: 541  GVLQLSQPVVSGVLPVGQPVRPGVLQLNQTVGTNILPVNQPVRPGASQNTTFLTSGSILR 600
            GVLQLSQPVVSGVLPVGQPVRPGVLQLNQTVGTNILPVNQPVRPGASQNTTFLTSGSILR
Sbjct: 541  GVLQLSQPVVSGVLPVGQPVRPGVLQLNQTVGTNILPVNQPVRPGASQNTTFLTSGSILR 600

Query: 601  QLIPTGKQVNGIPTYTLAPVSVTLPVPPGGLATVAPPQMPIQLLPSGAAAPMAGSMPGMP 660
            QLIPTGKQVNGIPTYTLAPVSVTLPVPPGGLATVAPPQMPIQLLPSGAAAPMAGSMPGMP
Sbjct: 601  QLIPTGKQVNGIPTYTLAPVSVTLPVPPGGLATVAPPQMPIQLLPSGAAAPMAGSMPGMP 660

Query: 661  SPPVLVNAAQSVFVQASSSAADTNQVLKQAKQWKTCPVCNELFPSNVYQVHMEVAHKHSE 720
            SPPVLVNAAQSVFVQASSSAADTNQVLKQAKQWKTCPVCNELFPSNVYQVHMEVAHKHSE
Sbjct: 661  SPPVLVNAAQSVFVQASSSAADTNQVLKQAKQWKTCPVCNELFPSNVYQVHMEVAHKHSE 720

Query: 721  SKSGEKLEPEKLAACAPFLKWMREKTVRCLSCKCLVSEEELIHHLLMHGLGCLFCPCTFH 780
            SKSGEKLEPEKLAACAPFLKWMREKTVRCLSCKCLVSEEELIHHLLMHGLGCLFCPCTFH
Sbjct: 721  SKSGEKLEPEKLAACAPFLKWMREKTVRCLSCKCLVSEEELIHHLLMHGLGCLFCPCTFH 780

Query: 781  DIKGLSEHSRNRHLGKKKLPMDYSNRGFQLDVDANGNLLFPHLDFITILPKEKLGEREVY 840
            DIKGLSEHSRNRHLGKKKLPMDYSNRGFQLDVDANGNLLFPHLDFITILPKEKLGEREVY
Sbjct: 781  DIKGLSEHSRNRHLGKKKLPMDYSNRGFQLDVDANGNLLFPHLDFITILPKEKLGEREVY 840

Query: 841  LAILAGIHSKSLVPVYVKVRPQAEGTPGSTGKRVSTCPFCFGPFVTTEAYELHLKERHHI 900
            LAILAGIHSKSLVPVYVKVRPQAEGTPGSTGKRVSTCPFCFGPFVTTEAYELHLKERHHI
Sbjct: 841  LAILAGIHSKSLVPVYVKVRPQAEGTPGSTGKRVSTCPFCFGPFVTTEAYELHLKERHHI 900

Query: 901  MPTVHTVLKSPAFKCIHCCGVYTGNMTLAAIAVHLVRCRSAPKDSSSDLQAQPGFIHNSE 960
            MPTVHTVLKSPAFKCIHCCGVYTGNMTLAAIAVHLVRCRSAPKDSSSDLQAQPGFIHNSE
Sbjct: 901  MPTVHTVLKSPAFKCIHCCGVYTGNMTLAAIAVHLVRCRSAPKDSSSDLQAQPGFIHNSE 960

Query: 961  LLLVSGEVMHDSSFSVKRKLPDGHLGAEDQRHGEEQPPILNADAAPGPEKVTSVVPFKRQ 1020
            LLLVSGEVMHDSSFSVKRKLPDGHLGAEDQRHGEEQPPILNADAAPGPEKVTSVVPFKRQ
Sbjct: 961  LLLVSGEVMHDSSFSVKRKLPDGHLGAEDQRHGEEQPPILNADAAPGPEKVTSVVPFKRQ 1020

Query: 1021 RNESRTEGPIVKDEALQILALDPKKYEGRSYEEKKQFLKDYFHKKPYPSKKEIELLSSLF 1080
            RNESRTEGPIVKDEALQILALDPKKYEGRSYEEKKQFLKDYFHKKPYPSKKEIELLSSLF
Sbjct: 1021 RNESRTEGPIVKDEALQILALDPKKYEGRSYEEKKQFLKDYFHKKPYPSKKEIELLSSLF 1080

Query: 1081 WVWKIDVASFFGKRRYICMKAIKNHKPSVLLGFDMSELKNVKHRLNFEYEP 1131
            WVWKIDVASFFGKRRYICMKAIKNHKPSVLLGFDMSELKNVKHRLNFEYEP
Sbjct: 1081 WVWKIDVASFFGKRRYICMKAIKNHKPSVLLGFDMSELKNVKHRLNFEYEP 1131


>gi|31563503 activity-dependent neuroprotector [Homo sapiens]
          Length = 1102

 Score =  249 bits (637), Expect = 8e-66
 Identities = 182/548 (33%), Positives = 257/548 (46%), Gaps = 102/548 (18%)

Query: 629  GGLATVAPPQMPI---QLLPSG------------AAAPMAGSMPG----------MPSPP 663
            GG A V+ PQ      QLLPSG            + AP   S+            + SP 
Sbjct: 352  GGNAPVSIPQQSQSVKQLLPSGNGRSYGLGSEQRSQAPARYSLQSANASSLSSGQLKSPS 411

Query: 664  VLVNAAQSVFVQASS--SAADTNQV---LKQAKQWKTCPVCNELFPSNVYQVHMEVAHKH 718
            +  + A  V  Q+SS  +AA T          ++WK C +CNELFP NVY VH E  HK 
Sbjct: 412  LSQSQASRVLGQSSSKPAAAATGPPPGNTSSTQKWKICTICNELFPENVYSVHFEKEHK- 470

Query: 719  SESKSGEKLEPEKLAACAPFLKWMREKTVRCLSCKCLVSEEELIHHLLMHGLGCLFCPCT 778
                       EK+ A A ++  +   T +CL C   +  + L++H+L+HGL C +C  T
Sbjct: 471  ----------AEKVPAVANYIMKIHNFTSKCLYCNRYLPTDTLLNHMLIHGLSCPYCRST 520

Query: 779  FHDIKGLSEHSRNRHLGKKKLPMDYSNRGFQLDVDANGNLLFPHLDFITILPKEKLGERE 838
            F+D++ ++ H R  H+ ++  P   S   F L +   G+    HL   T   ++   E  
Sbjct: 521  FNDVEKMAAHMRMVHIDEEMGPKTDSTLSFDLTLQ-QGSHTNIHLLVTTYNLRDAPAESV 579

Query: 839  VYLAI---------LAGIHSKSLVPVYVKVRPQAEGTPGSTGKRVSTCPFCF----GPFV 885
             Y A             +  K+ +PV  K  PQA   P       + CP CF    GP  
Sbjct: 580  AYHAQNNPPVPPKPQPKVQEKADIPV--KSSPQA-AVPYKKDVGKTLCPLCFSILKGPI- 635

Query: 886  TTEAYELHLKERHHIMPTVHTVLKSPAFKCIHCCGVYTGNMTLAAIAVHLVRCRSAPK-D 944
             ++A   HL+ERH ++ TVH V K   +KCIHC GVYT NMT + I +HLV CR   K  
Sbjct: 636  -SDALAHHLRERHQVIQTVHPVEKKLTYKCIHCLGVYTSNMTASTITLHLVHCRGVGKTQ 694

Query: 945  SSSDLQAQPGFIHNSELLLVSGEVMHDSSFSV--KRKLPDGHLGAEDQRHGEEQPPILNA 1002
            +  D    P  ++ S  L           F +  KRKL D    ++     EE+P     
Sbjct: 695  NGQDKTNAPSRLNQSPSLAPVKRTYEQMEFPLLKKRKLDD---DSDSPSFFEEKP----- 746

Query: 1003 DAAPGPEKVTSVVPFKRQRNESRTEGPIVKDEALQILALDPKKYEGRSYEEKKQFLKDYF 1062
                                    E P+V       LALDPK +E  SYE +K FL  YF
Sbjct: 747  ------------------------EEPVV-------LALDPKGHEDDSYEARKSFLTKYF 775

Query: 1063 HKKPYPSKKEIELLSSLFWVWKIDVASFFGKRRYICMKAIKNHKPSVLLGFDMSELKNVK 1122
            +K+PYP+++EIE L++  W+WK D+AS F  +R  C++  + +KP VLLGF+M EL  VK
Sbjct: 776  NKQPYPTRREIEKLAASLWLWKSDIASHFSNKRKKCVRDCEKYKPGVLLGFNMKELNKVK 835

Query: 1123 HRLNFEYE 1130
            H ++F+ E
Sbjct: 836  HEMDFDAE 843



 Score =  172 bits (436), Expect = 2e-42
 Identities = 110/379 (29%), Positives = 183/379 (48%), Gaps = 37/379 (9%)

Query: 1   MFQIPVENLDNIRKVRKKVKGILVDIGLDSCKELLKDLKGFDPGEKYFHNTSWGDVSLWE 60
           MFQ+PV NL ++RK RK VK IL DIGL+ CKE ++D K F+P + Y  NT+W DV LW+
Sbjct: 1   MFQLPVNNLGSLRKARKTVKKILSDIGLEYCKEHIEDFKQFEPNDFYLKNTTWEDVGLWD 60

Query: 61  PS-GKKVRYRTKPYCCGLCKYSTKVLTSFKNHLHRYHEDEIDQELVIPCPNCVFASQPKV 119
           PS  K   YRTKP+CC  C +S+K  +++K+H    H ++ +  +++ CP C F +  K 
Sbjct: 61  PSLTKNQDYRTKPFCCSACPFSSKFFSAYKSHFRNVHSEDFENRILLNCPYCTFNADKKT 120

Query: 120 VGRHFRMFHAPVRKVQNYTVNILGE------TKSSRSDVIS---FTCLKCNFSNTLYYSM 170
           +  H ++FHAP     + +++   +       K  ++D +    + C KC + + LY  +
Sbjct: 121 LETHIKIFHAPNASAPSSSLSTFKDKNKNDGLKPKQADSVEQAVYYCKKCTYRDPLYEIV 180

Query: 171 KKHVLVAHFHYLINSYFGLRTEEMGEQPKTNDTVSIEKIPPPDKYYCKKCNANASSQDAL 230
           +KH+   HF ++   Y      + GE+                  +CK+C     S +AL
Sbjct: 181 RKHIYREHFQHVAAPYIA----KAGEKSLNGAVPLGSNAREESSIHCKRCLFMPKSYEAL 236

Query: 231 MYHILTSDIHRDLENKLRSVISEH---IKRTGLLKQTHIAPKP--------AAHLAAPAN 279
           + H++  + H  +  ++ ++I      + R+  L    IAPKP           + + A+
Sbjct: 237 VQHVI--EDHERIGYQVTAMIGHTNVVVPRSKPLML--IAPKPQDKKSMGLPPRIGSLAS 292

Query: 280 GSAPSAPAQPPCFHLALPQ---NSPSPAAGQPVTVAQGAPGSLTHSPPAAGQSHMTLVSS 336
           G+  S P+Q     L++P+   NS        V + Q       +   + GQ +    S 
Sbjct: 293 GNVRSLPSQQMVNRLSIPKPNLNSTGVNMMSSVHLQQN-----NYGVKSVGQGYSVGQSM 347

Query: 337 PLPVGQNSLTLQPPAPQPV 355
            L +G N+    P   Q V
Sbjct: 348 RLGLGGNAPVSIPQQSQSV 366


>gi|12229217 activity-dependent neuroprotector [Homo sapiens]
          Length = 1102

 Score =  249 bits (637), Expect = 8e-66
 Identities = 182/548 (33%), Positives = 257/548 (46%), Gaps = 102/548 (18%)

Query: 629  GGLATVAPPQMPI---QLLPSG------------AAAPMAGSMPG----------MPSPP 663
            GG A V+ PQ      QLLPSG            + AP   S+            + SP 
Sbjct: 352  GGNAPVSIPQQSQSVKQLLPSGNGRSYGLGSEQRSQAPARYSLQSANASSLSSGQLKSPS 411

Query: 664  VLVNAAQSVFVQASS--SAADTNQV---LKQAKQWKTCPVCNELFPSNVYQVHMEVAHKH 718
            +  + A  V  Q+SS  +AA T          ++WK C +CNELFP NVY VH E  HK 
Sbjct: 412  LSQSQASRVLGQSSSKPAAAATGPPPGNTSSTQKWKICTICNELFPENVYSVHFEKEHK- 470

Query: 719  SESKSGEKLEPEKLAACAPFLKWMREKTVRCLSCKCLVSEEELIHHLLMHGLGCLFCPCT 778
                       EK+ A A ++  +   T +CL C   +  + L++H+L+HGL C +C  T
Sbjct: 471  ----------AEKVPAVANYIMKIHNFTSKCLYCNRYLPTDTLLNHMLIHGLSCPYCRST 520

Query: 779  FHDIKGLSEHSRNRHLGKKKLPMDYSNRGFQLDVDANGNLLFPHLDFITILPKEKLGERE 838
            F+D++ ++ H R  H+ ++  P   S   F L +   G+    HL   T   ++   E  
Sbjct: 521  FNDVEKMAAHMRMVHIDEEMGPKTDSTLSFDLTLQ-QGSHTNIHLLVTTYNLRDAPAESV 579

Query: 839  VYLAI---------LAGIHSKSLVPVYVKVRPQAEGTPGSTGKRVSTCPFCF----GPFV 885
             Y A             +  K+ +PV  K  PQA   P       + CP CF    GP  
Sbjct: 580  AYHAQNNPPVPPKPQPKVQEKADIPV--KSSPQA-AVPYKKDVGKTLCPLCFSILKGPI- 635

Query: 886  TTEAYELHLKERHHIMPTVHTVLKSPAFKCIHCCGVYTGNMTLAAIAVHLVRCRSAPK-D 944
             ++A   HL+ERH ++ TVH V K   +KCIHC GVYT NMT + I +HLV CR   K  
Sbjct: 636  -SDALAHHLRERHQVIQTVHPVEKKLTYKCIHCLGVYTSNMTASTITLHLVHCRGVGKTQ 694

Query: 945  SSSDLQAQPGFIHNSELLLVSGEVMHDSSFSV--KRKLPDGHLGAEDQRHGEEQPPILNA 1002
            +  D    P  ++ S  L           F +  KRKL D    ++     EE+P     
Sbjct: 695  NGQDKTNAPSRLNQSPSLAPVKRTYEQMEFPLLKKRKLDD---DSDSPSFFEEKP----- 746

Query: 1003 DAAPGPEKVTSVVPFKRQRNESRTEGPIVKDEALQILALDPKKYEGRSYEEKKQFLKDYF 1062
                                    E P+V       LALDPK +E  SYE +K FL  YF
Sbjct: 747  ------------------------EEPVV-------LALDPKGHEDDSYEARKSFLTKYF 775

Query: 1063 HKKPYPSKKEIELLSSLFWVWKIDVASFFGKRRYICMKAIKNHKPSVLLGFDMSELKNVK 1122
            +K+PYP+++EIE L++  W+WK D+AS F  +R  C++  + +KP VLLGF+M EL  VK
Sbjct: 776  NKQPYPTRREIEKLAASLWLWKSDIASHFSNKRKKCVRDCEKYKPGVLLGFNMKELNKVK 835

Query: 1123 HRLNFEYE 1130
            H ++F+ E
Sbjct: 836  HEMDFDAE 843



 Score =  172 bits (436), Expect = 2e-42
 Identities = 110/379 (29%), Positives = 183/379 (48%), Gaps = 37/379 (9%)

Query: 1   MFQIPVENLDNIRKVRKKVKGILVDIGLDSCKELLKDLKGFDPGEKYFHNTSWGDVSLWE 60
           MFQ+PV NL ++RK RK VK IL DIGL+ CKE ++D K F+P + Y  NT+W DV LW+
Sbjct: 1   MFQLPVNNLGSLRKARKTVKKILSDIGLEYCKEHIEDFKQFEPNDFYLKNTTWEDVGLWD 60

Query: 61  PS-GKKVRYRTKPYCCGLCKYSTKVLTSFKNHLHRYHEDEIDQELVIPCPNCVFASQPKV 119
           PS  K   YRTKP+CC  C +S+K  +++K+H    H ++ +  +++ CP C F +  K 
Sbjct: 61  PSLTKNQDYRTKPFCCSACPFSSKFFSAYKSHFRNVHSEDFENRILLNCPYCTFNADKKT 120

Query: 120 VGRHFRMFHAPVRKVQNYTVNILGE------TKSSRSDVIS---FTCLKCNFSNTLYYSM 170
           +  H ++FHAP     + +++   +       K  ++D +    + C KC + + LY  +
Sbjct: 121 LETHIKIFHAPNASAPSSSLSTFKDKNKNDGLKPKQADSVEQAVYYCKKCTYRDPLYEIV 180

Query: 171 KKHVLVAHFHYLINSYFGLRTEEMGEQPKTNDTVSIEKIPPPDKYYCKKCNANASSQDAL 230
           +KH+   HF ++   Y      + GE+                  +CK+C     S +AL
Sbjct: 181 RKHIYREHFQHVAAPYIA----KAGEKSLNGAVPLGSNAREESSIHCKRCLFMPKSYEAL 236

Query: 231 MYHILTSDIHRDLENKLRSVISEH---IKRTGLLKQTHIAPKP--------AAHLAAPAN 279
           + H++  + H  +  ++ ++I      + R+  L    IAPKP           + + A+
Sbjct: 237 VQHVI--EDHERIGYQVTAMIGHTNVVVPRSKPLML--IAPKPQDKKSMGLPPRIGSLAS 292

Query: 280 GSAPSAPAQPPCFHLALPQ---NSPSPAAGQPVTVAQGAPGSLTHSPPAAGQSHMTLVSS 336
           G+  S P+Q     L++P+   NS        V + Q       +   + GQ +    S 
Sbjct: 293 GNVRSLPSQQMVNRLSIPKPNLNSTGVNMMSSVHLQQN-----NYGVKSVGQGYSVGQSM 347

Query: 337 PLPVGQNSLTLQPPAPQPV 355
            L +G N+    P   Q V
Sbjct: 348 RLGLGGNAPVSIPQQSQSV 366


>gi|33286442 BCL6 co-repressor-like 1 [Homo sapiens]
          Length = 1711

 Score = 75.1 bits (183), Expect = 4e-13
 Identities = 129/470 (27%), Positives = 178/470 (37%), Gaps = 68/470 (14%)

Query: 261 LKQTHIAPKPAAHLAAPANGSAPSAPAQPPCFHLALPQNSPSPAAGQ-PVTVAQGAPGSL 319
           L  T+ +P PA  +  PA GSA    + P  F + L   +P P +G  PV VA   P   
Sbjct: 191 LVTTNFSPLPAP-ICPPAPGSASVPHSVPDAFQVPLSVPAPVPHSGLVPVQVATSVPAP- 248

Query: 320 THSPPAAG--------QSHMTLVSSPLPVGQNSLTLQP-----PAPQPVFLSHGVPLHQS 366
             SPP A          S  TL+S   P+  ++  L P     P   PV LS   P   S
Sbjct: 249 --SPPLAPVPALAPAPPSVPTLISDSNPLSVSASVLVPVPASAPPSGPVPLSAPAPAPLS 306

Query: 367 VNPPVLPLSQPVGPVNKSVGTSVLPINQTVRPGVLPLTQPVGPINRPVGPGVLPVSPSVT 426
           V     PL+    PV  S  T VL       P   P+  P+ P + P      P  P  T
Sbjct: 307 VPVSAPPLALIQAPVPPSAPTLVL------APVPTPVLAPM-PASTPPAAPAPPSVPMPT 359

Query: 427 PGVLQAVSPGVLSVSRAVPS-GVLPAGQMTPAGQMTPAGVIPGQTATSGVLPTGQMVQSG 485
           P      S G  S    +P+    P    TPA   TPA   P   AT   +PT   + + 
Sbjct: 360 P----TPSSGPPSTPTLIPAFAPTPVPAPTPAPIFTPAPT-PMPAATPAAIPTSAPIPAS 414

Query: 486 VLPVGQTAPSRVLPPGQTAPLRVISAGQVVPSGLLSPNQTVSSSAVVPVNQGVNSGVLQL 545
                  + SRV  P   AP          P  +L+P+Q +    + P + G    V  L
Sbjct: 415 F------SLSRVCFPAAQAPAMQKVPLSFQPGTVLTPSQPL--VYIPPPSCGQPLSVATL 466

Query: 546 SQPV-VSGVLPVGQPVRPGVLQLNQTVGTNILPVNQPVRPGASQNTTFLTSGSILRQLIP 604
              + VS  L +  PV P  LQ     G    P  +   P A      LTS S L  L  
Sbjct: 467 PTTLGVSSTLTL--PVLPSYLQDRCLPGVLASPELRSY-PYAFSVARPLTSDSKLVSL-- 521

Query: 605 TGKQVNGIPTYTLAPVSVTLPVP---PGGL---------ATVAPPQMPIQLLPSGAAAPM 652
              +VN +P  + +  + T P P   PG L         A V P   P+   PSG++AP 
Sbjct: 522 ---EVNRLPCTSPSGSTTTQPAPDGVPGPLADTSLVTASAKVLPTPQPLLPAPSGSSAP- 577

Query: 653 AGSMPGMPSPPVLVNAAQSVFVQASSSAADTNQVLKQAKQWKTCPVCNEL 702
                  P P  + +  +      S + +      +  ++  + P C+E+
Sbjct: 578 -------PHPAKMPSGTEQQTEGTSVTFSPLKSPPQLEREMASPPECSEM 620



 Score = 40.4 bits (93), Expect = 0.010
 Identities = 92/346 (26%), Positives = 124/346 (35%), Gaps = 59/346 (17%)

Query: 361 VPLHQSVNPPVLPLSQPVGPVNKSVGTSVLPINQTVRPGV---------LPLTQPVGPIN 411
           VPL    +   LP S      N     S  P+N  +   V         L   Q VG  N
Sbjct: 113 VPLSSPGDGLKLPASDSAEASNSRADCSWTPLNTQMSKQVDCSPAGVKALDSRQGVGEKN 172

Query: 412 R----PVGPGVLPVS---PSVT------PGVLQAVSPGVLSVSRAVPSGV-LPAGQMTPA 457
                 +G GV PV    P VT      P  +   +PG  SV  +VP    +P     P 
Sbjct: 173 TFILATLGTGV-PVEGTLPLVTTNFSPLPAPICPPAPGSASVPHSVPDAFQVPLSVPAPV 231

Query: 458 GQMTPAGVIPGQTATSGVLPTGQMVQSGVLPVGQTAPSRVLPP---GQTAPLRVISAGQV 514
                +G++P Q ATS   P+  +      PV   AP+    P     + PL V SA  +
Sbjct: 232 PH---SGLVPVQVATSVPAPSPPLA-----PVPALAPAPPSVPTLISDSNPLSV-SASVL 282

Query: 515 VPSGLLSPNQ---TVSSSAVVPVNQGVNSGVLQLSQPVVSGVLP--VGQPVRPGVLQLNQ 569
           VP    +P      +S+ A  P++  V++  L L Q  V    P  V  PV   VL    
Sbjct: 283 VPVPASAPPSGPVPLSAPAPAPLSVPVSAPPLALIQAPVPPSAPTLVLAPVPTPVLAPMP 342

Query: 570 TVGTNILPVNQPVRPGASQNTTFLTSGSILRQLIPTGKQVNGIPTYTLAPVSVTLPVPPG 629
                  P   P  P     T   +SG      +        IP +   PV    P P  
Sbjct: 343 AS----TPPAAPAPPSVPMPTPTPSSGPPSTPTL--------IPAFAPTPVPAPTPAP-- 388

Query: 630 GLATVAPPQMPI---QLLPSGAAAPMAGSMPGMPSPPVLVNAAQSV 672
            + T AP  MP      +P+ A  P + S+  +  P     A Q V
Sbjct: 389 -IFTPAPTPMPAATPAAIPTSAPIPASFSLSRVCFPAAQAPAMQKV 433



 Score = 38.1 bits (87), Expect = 0.048
 Identities = 101/427 (23%), Positives = 146/427 (34%), Gaps = 106/427 (24%)

Query: 266 IAPKPAAHLAAPANGSAPSAPAQPPCFHLALPQNSPSPAAGQPVTVAQ-GAPGSLTH--- 321
           + P P   L AP+  SAP  PA+       +P  +     G  VT +   +P  L     
Sbjct: 560 VLPTPQPLLPAPSGSSAPPHPAK-------MPSGTEQQTEGTSVTFSPLKSPPQLEREMA 612

Query: 322 SPPAAGQSHMTLVS----SPLPVGQNSLTLQPPAPQPVFLSHGVPLHQSVNPPVLPLSQP 377
           SPP   +  + L S      LP+     T   P   PV  S    L   ++         
Sbjct: 613 SPPECSEMPLDLSSKSNRQKLPLPNQRKTPPMPVLTPVHTSSKALLSTVLSRSQRTTQAA 672

Query: 378 VGPVNKSVGTSVLPI-----------------NQTVRPGVLPLTQPVGPINRPVGPGVLP 420
            G V   +G++  P                  N T     +P T  VG  N      +L 
Sbjct: 673 GGNVTSCLGSTSSPFVIFPEIVRNGDPSTWVKNSTALISTIPGTY-VGVANPVPASLLLN 731

Query: 421 VSPSV----TPGVLQAVSPGVLSVSRAVPSGVLPA-----------GQMTPAGQMTPAGV 465
             P++     P  L    P +  + +  P G               GQ +   + TPA +
Sbjct: 732 KDPNLGLNRDPRHLPKQEP-ISIIDQGEPKGTGATCGKKGSQAGAEGQPSTVKRYTPARI 790

Query: 466 IPG-------------QTATSGVLP----TGQMVQSGVLPVGQTAPSRVLPPGQTAPLRV 508
            PG              T  + + P     G+   + VLPVG +   +         + +
Sbjct: 791 APGLPGCQTKELSLWKPTGPANIYPRCSVNGKPTSTQVLPVGWSPYHQ----ASLLSIGI 846

Query: 509 ISAGQVVPS--GLLSPNQTVSSSAVVPVNQGVNSGVLQLSQPVVSGVLPVGQPVRPGVLQ 566
            SAGQ+ PS    + P   VS            SGV  LS       LP GQP RP    
Sbjct: 847 SSAGQLTPSQGAPIRPTSVVSEF----------SGVPSLSSSEAVHGLPEGQP-RP---- 891

Query: 567 LNQTVGTNILPVNQPVRPGASQNTTFLTSGSILRQLIPTGKQVNGIPTYTLAPVSVTLPV 626
                G + +P   PV    ++N T   +        P  +QVN +   TL+P + TL +
Sbjct: 892 -----GGSFVPEQDPV----TKNKTCRIAAK------PYEEQVNPV-LLTLSPQTGTLAL 935

Query: 627 ---PPGG 630
              P GG
Sbjct: 936 SVQPSGG 942


>gi|32455273 WNK lysine deficient protein kinase 2 [Homo sapiens]
          Length = 2217

 Score = 73.9 bits (180), Expect = 8e-13
 Identities = 120/442 (27%), Positives = 166/442 (37%), Gaps = 82/442 (18%)

Query: 267  APKPAAHLAAPANGSAPSAPAQPPCFHLALPQNSPSPAAGQPVTVAQGAPGSLTHSP--P 324
            AP PA  + +P     P            LPQ+ PS  A Q  T A G P     +P  P
Sbjct: 644  APSPAQCVCSPPVSEGP-----------VLPQSLPSLGAYQQPTAAPGLPVGSVPAPACP 692

Query: 325  AAGQSH-----------MTLVSSPLPVGQNSLTLQPPAPQPVFLSHGVPLHQSVNP-PVL 372
             + Q H           +   S+P+P G       PP  QP  L+   PL Q + P PV+
Sbjct: 693  PSLQQHFPDPAMSFAPVLPPPSTPMPTGPGQPA--PPGQQPPPLAQPTPLPQVLAPQPVV 750

Query: 373  PLSQPVGPVNKSVGTSVLPINQTVRPGVL-PLTQPVGPINRPVG--PGVLPVSPSVTPGV 429
            PL QPV P    +   + P +Q   P  L PL  P  P+ +P+   P  +P  P V P  
Sbjct: 751  PL-QPVPP---HLPPYLAPASQVGAPAQLKPLQMPQAPL-QPLAQVPPQMPPIPVVPPIT 805

Query: 430  LQAVSPGVLSVSRAVPSGVLPAGQMTPAGQMTPAGVIPGQTATSGVLPTGQMVQSGVLPV 489
              A   G+      +P+  +P   + P    +PA ++P   A          +Q+  LP 
Sbjct: 806  PLAGIDGLPPALPDLPTATVP--PVPPPQYFSPAVILPSLAAPLPPASPALPLQAVKLP- 862

Query: 490  GQTAPSRVLPPGQTAPLRVISAGQVVPSGLLSPNQTVSSSAVVPVNQGVNSGVLQLSQPV 549
                     PPG  APL        +P   + PN    + A +P+      GV  LS   
Sbjct: 863  --------HPPG--APL-------AMPCRTIVPN----APATIPLLAVAPPGVAALSIHS 901

Query: 550  VSGVLPVGQPVRPGVLQLNQTVGTNILPVNQPVRPGASQNTTFLTSGSILRQLIPTGKQV 609
                LP GQPV P            + P + P  P  +      T         PT    
Sbjct: 902  AVAQLP-GQPVYPAAF-------PQMAPTDVPPSPHHTVQNMRATPPQPALPPQPT---- 949

Query: 610  NGIPTYTLAPVSVTLPVPPGGLATVAPPQ---MPIQLLPSGAAAPMAGSMPGMPSPPVLV 666
              +P   + P   TLP  P     V PPQ    P  +LP     P    +P  P+ PV  
Sbjct: 950  --LPPQPVLPPQPTLPPQP-----VLPPQPTRPPQPVLPPQPMLPPQPVLPPQPALPVRP 1002

Query: 667  NAAQ-SVFVQASSSAADTNQVL 687
               Q  +  QA+ +A   +Q+L
Sbjct: 1003 EPLQPHLPEQAAPAATPGSQIL 1024



 Score = 50.1 bits (118), Expect = 1e-05
 Identities = 72/256 (28%), Positives = 106/256 (41%), Gaps = 34/256 (13%)

Query: 261  LKQTHIAPKPAAHLAAPANGSAPSAPAQPPCFHLALP-------QNSPSPAAGQPVTVAQ 313
            L+   +   P A LA P     P+APA  P   +A P        ++ +   GQPV  A 
Sbjct: 856  LQAVKLPHPPGAPLAMPCRTIVPNAPATIPLLAVAPPGVAALSIHSAVAQLPGQPVYPAA 915

Query: 314  GAPGSLTHSPPAAGQSHMTLVSSPLPVGQNSLTLQPP-APQPVFLSHGVPLHQSVNP-PV 371
                + T  PP+    H T+ +      Q +L  QP   PQPV     +P   ++ P PV
Sbjct: 916  FPQMAPTDVPPS---PHHTVQNMRATPPQPALPPQPTLPPQPV-----LPPQPTLPPQPV 967

Query: 372  LPLSQPVGPVNKSVGTSVLPINQTVRPGVLPLTQPVGPIN-RPVGPGVLP--VSPSVTPG 428
            LP  QP  P        VLP    + P  +   QP  P+   P+ P  LP   +P+ TPG
Sbjct: 968  LP-PQPTRPPQ-----PVLPPQPMLPPQPVLPPQPALPVRPEPLQPH-LPEQAAPAATPG 1020

Query: 429  ---VLQAVSPGVLSVSRAVPS-GVLPAGQMTPAGQMTPAGVIPGQTATSGVLPTGQMVQS 484
               +L   +P  + V+  VP+  V PA  ++P     P  ++P         P+     S
Sbjct: 1021 SQILLGHPAPYAVDVAAQVPTVPVPPAAVLSPP---LPEVLLPAAPELLPQFPSSLATVS 1077

Query: 485  GVLPVGQTAPSRVLPP 500
              +    T  + +LPP
Sbjct: 1078 ASVQSVPTQTATLLPP 1093



 Score = 42.7 bits (99), Expect = 0.002
 Identities = 48/181 (26%), Positives = 64/181 (35%), Gaps = 13/181 (7%)

Query: 266  IAPKPAAHLAAPANGSAPSAPAQPPCFHLALPQNSPSPAAGQPVTVAQGAPGSLTHSPPA 325
            +AP      A P +G+AP+    P       P +  +  AG P T  QG    L  S P 
Sbjct: 1384 LAPSSPPVTALPQDGAAPATSTMPE------PASGTASQAGGPGT-PQGLTSELETSQPL 1436

Query: 326  AGQSHMTLVSSPLPVGQNSLTLQPPAPQPVFLSHGVPLHQSVNPPVLPLSQPVGPVNKSV 385
            A      L   PL VG    T   PAP+           + + PP    S   G    ++
Sbjct: 1437 AETHEAPLAVQPLVVGLAPCT---PAPEAASTRDASAPREPLPPPAPEPSPHSGTPQPAL 1493

Query: 386  GTSVLPINQTVRPGVLPLTQPVGPINRPVGPGVLPVSPSVTPGVLQAVSPGVLSVSRAVP 445
            G     +   V    L  +Q   P   P+GP V P  PS      +   P V  V   + 
Sbjct: 1494 GQPAPLLPAAVGAVSLATSQLPSP---PLGPTVPPQPPSALESDGEGPPPRVGFVDSTIK 1550

Query: 446  S 446
            S
Sbjct: 1551 S 1551



 Score = 37.0 bits (84), Expect = 0.11
 Identities = 32/123 (26%), Positives = 48/123 (39%), Gaps = 26/123 (21%)

Query: 251  ISEHIKRTGLLKQTHIAP-------------KPAAHLAAPANGSAPSAPAQPPCFHLALP 297
            ++  ++ +  L +TH AP              PA   A+  + SAP  P  PP    +  
Sbjct: 1426 LTSELETSQPLAETHEAPLAVQPLVVGLAPCTPAPEAASTRDASAPREPLPPPAPEPSPH 1485

Query: 298  QNSPSPAAGQPVTVAQGAPGSLTHSPPAAGQSHMTLVSSPLPVGQNSLTLQPPAPQPVFL 357
              +P PA GQP  +   A G+            ++L +S LP      T+ PP P     
Sbjct: 1486 SGTPQPALGQPAPLLPAAVGA------------VSLATSQLPSPPLGPTV-PPQPPSALE 1532

Query: 358  SHG 360
            S G
Sbjct: 1533 SDG 1535



 Score = 30.4 bits (67), Expect = 9.9
 Identities = 21/67 (31%), Positives = 30/67 (44%), Gaps = 2/67 (2%)

Query: 627  PPGGL-ATVAPPQMPIQLLPSGAAAPMAGSMPGMPSPPVLVNAAQSVFVQASSSAADTNQ 685
            PPG   A +AP   P+  LP   AAP   +MP  P+      A      Q  +S  +T+Q
Sbjct: 1376 PPGAPPAPLAPSSPPVTALPQDGAAPATSTMP-EPASGTASQAGGPGTPQGLTSELETSQ 1434

Query: 686  VLKQAKQ 692
             L +  +
Sbjct: 1435 PLAETHE 1441


>gi|126090892 aggrecan isoform 2 precursor [Homo sapiens]
          Length = 2416

 Score = 69.3 bits (168), Expect = 2e-11
 Identities = 104/370 (28%), Positives = 157/370 (42%), Gaps = 40/370 (10%)

Query: 334  VSSPLPVGQNSLTLQPPAPQPVFLSHGVPLHQSVNPPVLPLSQ-PVGPVNKSVGTSV--- 389
            V S LP G       P  P    L  G  + +     V  LS  P G V ++  + V   
Sbjct: 914  VESGLPSGDEERIEWPSTPTVGELPSGAEILEGSASGVGDLSGLPSGEVLETSASGVGDL 973

Query: 390  --LP---INQTVRPGVLPLTQ-PVGPINRPVGPGVLPVSPSVTPGVLQAVSPGVLSVSRA 443
              LP   + +T  PGV  ++  P G +     PGV  +S   +  VL+  +PGV  +S  
Sbjct: 974  SGLPSGEVLETTAPGVEDISGLPSGEVLETTAPGVEDISGLPSGEVLETTAPGVEDIS-G 1032

Query: 444  VPSGVLPAGQMTPAGQMTPAGVIPGQ---TATSGV-----LPTGQMVQSGVLPVGQTAPS 495
            +PSG +   + T  G    +G+  G+   T   GV     LP+G+++++    V   +  
Sbjct: 1033 LPSGEVL--ETTAPGVEDISGLPSGEVLETTAPGVEDISGLPSGEVLETTAPGVEDISG- 1089

Query: 496  RVLPPGQTAPLRVISAGQVVPSGLLSPNQTVSSSAVVPVNQGVNSG-VLQLSQPVVSGV- 553
              LP G+   L   + G    SGL S     +++  V    G+ SG VL+ + P V  + 
Sbjct: 1090 --LPSGEV--LETAAPGVEDISGLPSGEVLETAAPGVEDISGLPSGEVLETAAPGVEDIS 1145

Query: 554  -LPVGQPVRPGVLQLNQTVGTNILPVNQPVRPGASQNTTFLTSGSILRQLIPTGKQVNGI 612
             LP G+ +      +    G     V +   PG  ++ + L SG +L    P  + ++G+
Sbjct: 1146 GLPSGEVLETAAPGVEDISGLPSGEVLETAAPGV-EDISGLPSGEVLETAAPGVEDISGL 1204

Query: 613  PT----YTLAPVSVTLPVPPGG--LATVAPPQMPIQLLPSG----AAAPMAGSMPGMPSP 662
            P+     T AP    +   P G  L T AP    I  LPSG     AAP    + G+PS 
Sbjct: 1205 PSGEVLETAAPGVEDISGLPSGEVLETAAPGVEDISGLPSGEVLETAAPGVEDISGLPSG 1264

Query: 663  PVLVNAAQSV 672
             VL  AA  V
Sbjct: 1265 EVLETAAPGV 1274



 Score = 47.0 bits (110), Expect = 1e-04
 Identities = 95/381 (24%), Positives = 137/381 (35%), Gaps = 105/381 (27%)

Query: 391  PINQTVRPGVLPLTQPVG-----------------------------------PINRPVG 415
            P+  +  PG+LP   P G                                   P   P  
Sbjct: 748  PVGTSPLPGILPTWPPTGAATEESTEGPSATEVPSASEEPSPSEVPFPSEEPSPSEEPF- 806

Query: 416  PGVLPV-----------------SPSVTPGVLQ---AVSPGVLSVSRAVPSGVLPAGQMT 455
            P V P                  SPS  P   +     SP V S +  +PS    +G   
Sbjct: 807  PSVRPFPSVELFPSEEPFPSKEPSPSEEPSASEEPYTPSPPVPSWTE-LPSSGEESGAPD 865

Query: 456  PAGQMTPAGVIPGQTATSGV--------LPTGQMVQSGV-------LPVGQTAPS----R 496
             +G  T +G + G    SG         LP+G +  SG+       LPV    PS    R
Sbjct: 866  VSGDFTGSGDVSGHLDFSGQLSGDRASGLPSGDLDSSGLTSTVGSGLPVESGLPSGDEER 925

Query: 497  VLPPGQTAPLRVISAGQVVP---------SGLLSPNQTVSSSAVVPVNQGVNSG-VLQLS 546
            +  P       + S  +++          SGL S     +S++ V    G+ SG VL+ +
Sbjct: 926  IEWPSTPTVGELPSGAEILEGSASGVGDLSGLPSGEVLETSASGVGDLSGLPSGEVLETT 985

Query: 547  QPVVSGV--LPVGQPVR---PGVLQLNQTVGTNILPVNQPVRPGASQNTTFLTSGSILRQ 601
             P V  +  LP G+ +    PGV  ++      +L    P      ++ + L SG +L  
Sbjct: 986  APGVEDISGLPSGEVLETTAPGVEDISGLPSGEVLETTAP----GVEDISGLPSGEVLET 1041

Query: 602  LIPTGKQVNGIPT----YTLAPVSVTLPVPPGG--LATVAPPQMPIQLLPSG----AAAP 651
              P  + ++G+P+     T AP    +   P G  L T AP    I  LPSG     AAP
Sbjct: 1042 TAPGVEDISGLPSGEVLETTAPGVEDISGLPSGEVLETTAPGVEDISGLPSGEVLETAAP 1101

Query: 652  MAGSMPGMPSPPVLVNAAQSV 672
                + G+PS  VL  AA  V
Sbjct: 1102 GVEDISGLPSGEVLETAAPGV 1122



 Score = 46.6 bits (109), Expect = 1e-04
 Identities = 106/400 (26%), Positives = 164/400 (41%), Gaps = 57/400 (14%)

Query: 296  LPQNSPSPAAGQPVTVAQGAPGSLTHSPPAAGQSHMTLVSSPLPVGQNSLTLQPPAPQPV 355
            LP       A   V    G P        A G   +    S LP G+   T  P      
Sbjct: 1109 LPSGEVLETAAPGVEDISGLPSGEVLETAAPGVEDI----SGLPSGEVLETAAPGVEDIS 1164

Query: 356  FLSHGVPLHQSVNPPVLPLSQ-PVGPVNKSVGTSVLPIN--------QTVRPGVLPLTQ- 405
             L  G  L ++  P V  +S  P G V ++    V  I+        +T  PGV  ++  
Sbjct: 1165 GLPSGEVL-ETAAPGVEDISGLPSGEVLETAAPGVEDISGLPSGEVLETAAPGVEDISGL 1223

Query: 406  PVGPINRPVGPGVLPVSPSVTPGVLQAVSPGVLSVSRAVPSG-VLPAG-------QMTPA 457
            P G +     PGV  +S   +  VL+  +PGV  +S  +PSG VL             P+
Sbjct: 1224 PSGEVLETAAPGVEDISGLPSGEVLETAAPGVEDIS-GLPSGEVLETAAPGVEDISGLPS 1282

Query: 458  GQMTPAGVIPGQTATSGVLPTGQMVQSGVLPVGQTAPSRVLPPGQTAPLRVISAGQVVPS 517
            G++      PG    SG LP+G+++++    V + +    LP G+   L   + G    S
Sbjct: 1283 GEVLET-TAPGVEEISG-LPSGEVLETTAPGVDEISG---LPSGEV--LETTAPGVEEIS 1335

Query: 518  GLLSPNQTVSSSAVVPVNQGVNSG--VLQLSQPVVSGV-----LPVGQPVRPGVLQLNQT 570
            GL S     +S++ V    G+ SG  VL++S   VSGV     LP G+ V      +   
Sbjct: 1336 GLPSGEVLETSTSAVGDLSGLPSGGEVLEIS---VSGVEDISGLPSGEVVETSASGIED- 1391

Query: 571  VGTNILPVNQPVRPGAS--QNTTFLTSGSILRQLIPTG-KQVNGIPT------YTLAPVS 621
               + LP  + +   AS  ++ + L SG  + ++  +G   ++G+P+       + + V 
Sbjct: 1392 --VSELPSGEGLETSASGVEDLSRLPSGEEVLEISASGFGDLSGLPSGGEGLETSASEVG 1449

Query: 622  VTLP-VPPG--GLATVAPPQMPIQLLPSGAAAPMAGSMPG 658
              L  +P G  GL T A     +  LPSG    + GS  G
Sbjct: 1450 TDLSGLPSGREGLETSASGAEDLSGLPSG-KEDLVGSASG 1488


>gi|126090883 aggrecan isoform 1 precursor [Homo sapiens]
          Length = 2317

 Score = 69.3 bits (168), Expect = 2e-11
 Identities = 104/370 (28%), Positives = 157/370 (42%), Gaps = 40/370 (10%)

Query: 334  VSSPLPVGQNSLTLQPPAPQPVFLSHGVPLHQSVNPPVLPLSQ-PVGPVNKSVGTSV--- 389
            V S LP G       P  P    L  G  + +     V  LS  P G V ++  + V   
Sbjct: 914  VESGLPSGDEERIEWPSTPTVGELPSGAEILEGSASGVGDLSGLPSGEVLETSASGVGDL 973

Query: 390  --LP---INQTVRPGVLPLTQ-PVGPINRPVGPGVLPVSPSVTPGVLQAVSPGVLSVSRA 443
              LP   + +T  PGV  ++  P G +     PGV  +S   +  VL+  +PGV  +S  
Sbjct: 974  SGLPSGEVLETTAPGVEDISGLPSGEVLETTAPGVEDISGLPSGEVLETTAPGVEDIS-G 1032

Query: 444  VPSGVLPAGQMTPAGQMTPAGVIPGQ---TATSGV-----LPTGQMVQSGVLPVGQTAPS 495
            +PSG +   + T  G    +G+  G+   T   GV     LP+G+++++    V   +  
Sbjct: 1033 LPSGEVL--ETTAPGVEDISGLPSGEVLETTAPGVEDISGLPSGEVLETTAPGVEDISG- 1089

Query: 496  RVLPPGQTAPLRVISAGQVVPSGLLSPNQTVSSSAVVPVNQGVNSG-VLQLSQPVVSGV- 553
              LP G+   L   + G    SGL S     +++  V    G+ SG VL+ + P V  + 
Sbjct: 1090 --LPSGEV--LETAAPGVEDISGLPSGEVLETAAPGVEDISGLPSGEVLETAAPGVEDIS 1145

Query: 554  -LPVGQPVRPGVLQLNQTVGTNILPVNQPVRPGASQNTTFLTSGSILRQLIPTGKQVNGI 612
             LP G+ +      +    G     V +   PG  ++ + L SG +L    P  + ++G+
Sbjct: 1146 GLPSGEVLETAAPGVEDISGLPSGEVLETAAPGV-EDISGLPSGEVLETAAPGVEDISGL 1204

Query: 613  PT----YTLAPVSVTLPVPPGG--LATVAPPQMPIQLLPSG----AAAPMAGSMPGMPSP 662
            P+     T AP    +   P G  L T AP    I  LPSG     AAP    + G+PS 
Sbjct: 1205 PSGEVLETAAPGVEDISGLPSGEVLETAAPGVEDISGLPSGEVLETAAPGVEDISGLPSG 1264

Query: 663  PVLVNAAQSV 672
             VL  AA  V
Sbjct: 1265 EVLETAAPGV 1274



 Score = 47.0 bits (110), Expect = 1e-04
 Identities = 95/381 (24%), Positives = 137/381 (35%), Gaps = 105/381 (27%)

Query: 391  PINQTVRPGVLPLTQPVG-----------------------------------PINRPVG 415
            P+  +  PG+LP   P G                                   P   P  
Sbjct: 748  PVGTSPLPGILPTWPPTGAATEESTEGPSATEVPSASEEPSPSEVPFPSEEPSPSEEPF- 806

Query: 416  PGVLPV-----------------SPSVTPGVLQ---AVSPGVLSVSRAVPSGVLPAGQMT 455
            P V P                  SPS  P   +     SP V S +  +PS    +G   
Sbjct: 807  PSVRPFPSVELFPSEEPFPSKEPSPSEEPSASEEPYTPSPPVPSWTE-LPSSGEESGAPD 865

Query: 456  PAGQMTPAGVIPGQTATSGV--------LPTGQMVQSGV-------LPVGQTAPS----R 496
             +G  T +G + G    SG         LP+G +  SG+       LPV    PS    R
Sbjct: 866  VSGDFTGSGDVSGHLDFSGQLSGDRASGLPSGDLDSSGLTSTVGSGLPVESGLPSGDEER 925

Query: 497  VLPPGQTAPLRVISAGQVVP---------SGLLSPNQTVSSSAVVPVNQGVNSG-VLQLS 546
            +  P       + S  +++          SGL S     +S++ V    G+ SG VL+ +
Sbjct: 926  IEWPSTPTVGELPSGAEILEGSASGVGDLSGLPSGEVLETSASGVGDLSGLPSGEVLETT 985

Query: 547  QPVVSGV--LPVGQPVR---PGVLQLNQTVGTNILPVNQPVRPGASQNTTFLTSGSILRQ 601
             P V  +  LP G+ +    PGV  ++      +L    P      ++ + L SG +L  
Sbjct: 986  APGVEDISGLPSGEVLETTAPGVEDISGLPSGEVLETTAP----GVEDISGLPSGEVLET 1041

Query: 602  LIPTGKQVNGIPT----YTLAPVSVTLPVPPGG--LATVAPPQMPIQLLPSG----AAAP 651
              P  + ++G+P+     T AP    +   P G  L T AP    I  LPSG     AAP
Sbjct: 1042 TAPGVEDISGLPSGEVLETTAPGVEDISGLPSGEVLETTAPGVEDISGLPSGEVLETAAP 1101

Query: 652  MAGSMPGMPSPPVLVNAAQSV 672
                + G+PS  VL  AA  V
Sbjct: 1102 GVEDISGLPSGEVLETAAPGV 1122



 Score = 46.6 bits (109), Expect = 1e-04
 Identities = 106/400 (26%), Positives = 164/400 (41%), Gaps = 57/400 (14%)

Query: 296  LPQNSPSPAAGQPVTVAQGAPGSLTHSPPAAGQSHMTLVSSPLPVGQNSLTLQPPAPQPV 355
            LP       A   V    G P        A G   +    S LP G+   T  P      
Sbjct: 1109 LPSGEVLETAAPGVEDISGLPSGEVLETAAPGVEDI----SGLPSGEVLETAAPGVEDIS 1164

Query: 356  FLSHGVPLHQSVNPPVLPLSQ-PVGPVNKSVGTSVLPIN--------QTVRPGVLPLTQ- 405
             L  G  L ++  P V  +S  P G V ++    V  I+        +T  PGV  ++  
Sbjct: 1165 GLPSGEVL-ETAAPGVEDISGLPSGEVLETAAPGVEDISGLPSGEVLETAAPGVEDISGL 1223

Query: 406  PVGPINRPVGPGVLPVSPSVTPGVLQAVSPGVLSVSRAVPSG-VLPAG-------QMTPA 457
            P G +     PGV  +S   +  VL+  +PGV  +S  +PSG VL             P+
Sbjct: 1224 PSGEVLETAAPGVEDISGLPSGEVLETAAPGVEDIS-GLPSGEVLETAAPGVEDISGLPS 1282

Query: 458  GQMTPAGVIPGQTATSGVLPTGQMVQSGVLPVGQTAPSRVLPPGQTAPLRVISAGQVVPS 517
            G++      PG    SG LP+G+++++    V + +    LP G+   L   + G    S
Sbjct: 1283 GEVLET-TAPGVEEISG-LPSGEVLETTAPGVDEISG---LPSGEV--LETTAPGVEEIS 1335

Query: 518  GLLSPNQTVSSSAVVPVNQGVNSG--VLQLSQPVVSGV-----LPVGQPVRPGVLQLNQT 570
            GL S     +S++ V    G+ SG  VL++S   VSGV     LP G+ V      +   
Sbjct: 1336 GLPSGEVLETSTSAVGDLSGLPSGGEVLEIS---VSGVEDISGLPSGEVVETSASGIED- 1391

Query: 571  VGTNILPVNQPVRPGAS--QNTTFLTSGSILRQLIPTG-KQVNGIPT------YTLAPVS 621
               + LP  + +   AS  ++ + L SG  + ++  +G   ++G+P+       + + V 
Sbjct: 1392 --VSELPSGEGLETSASGVEDLSRLPSGEEVLEISASGFGDLSGLPSGGEGLETSASEVG 1449

Query: 622  VTLP-VPPG--GLATVAPPQMPIQLLPSGAAAPMAGSMPG 658
              L  +P G  GL T A     +  LPSG    + GS  G
Sbjct: 1450 TDLSGLPSGREGLETSASGAEDLSGLPSG-KEDLVGSASG 1488


>gi|146219843 Snf2-related CBP activator protein [Homo sapiens]
          Length = 3230

 Score = 69.3 bits (168), Expect = 2e-11
 Identities = 113/429 (26%), Positives = 160/429 (37%), Gaps = 62/429 (14%)

Query: 304  AAGQPVTVAQGAPGSLTHSPPAAGQSHMTLVSSPLPVGQNSLTLQPPAPQPVFLSHG--- 360
            A GQP  + +    ++ H   A GQ H  L+S P  V         P P PV +      
Sbjct: 1227 AVGQPRPLQR----NVVHLVSAGGQHH--LISQPAHVALIQAVAPTPGPTPVSVLPSSTP 1280

Query: 361  --VPLHQSVNPPVLPLSQPVGPVNKSVGTSVLPINQTVRPGVLPLTQPVGPINRPVG--- 415
               P    ++ P+     P   VN + G   + + Q  R G+ P+  P+ P  RP     
Sbjct: 1281 STTPAPTGLSLPLAANQVPPTMVNNT-GVVKIVVRQAPRDGLTPVP-PLAPAPRPPSSGL 1338

Query: 416  PGVLPVSPSVTPGVLQAVSPGVLSVSRAVPSGVLP------------------AGQMTPA 457
            P VL   P++TPG L   + G        P+ V P                  A  +T +
Sbjct: 1339 PAVLNPRPTLTPGRLPTPTLGTARAPMPTPTLVRPLLKLVHSPSPEVSASAPGAAPLTIS 1398

Query: 458  GQMTPAGVIPGQTATSGVLPTGQMVQSGV-----LPVGQTAPSRV---LPPGQTAPLRV- 508
              +     +PG  ++   +P    + S V     +P+  + P  V   LP   +APL + 
Sbjct: 1399 SPLHVPSSLPGPASSPMPIPNSSPLASPVSSTVSVPLSSSLPISVPTTLPAPASAPLTIP 1458

Query: 509  ISAGQVVPSG--LLSPNQTVSSSAVVPVNQGVNSGVLQLSQPVVSGVLPVGQPVRPGVLQ 566
            ISA   V +    L  + T   + VVP   G  S     + P  S  L +G    P  L 
Sbjct: 1459 ISAPLTVSASGPALLTSVTPPLAPVVPAAPGPPSLAPSGASPSASA-LTLGLATAPS-LS 1516

Query: 567  LNQTVGTNIL---------PVNQPVRPGASQNTTFLTSGSILRQLIPTGKQVNGIPTYTL 617
             +QT G  +L          +N  V P  S     L   S L    P+           L
Sbjct: 1517 SSQTPGHPLLLAPTSSHVPGLNSTVAPACSP---VLVPASALASPFPSAPNPAPAQASLL 1573

Query: 618  APVSVTLPVPPGGLATVAPPQMPIQLLPSGAA--APMAGSMPGMPSPPVLVNAAQSVFVQ 675
            AP S         LA +A PQ  I L PS A   AP+    P   + PVL ++   V V 
Sbjct: 1574 APASSASQALATPLAPMAAPQTAI-LAPSPAPPLAPLPVLAPSPGAAPVLASSQTPVPVM 1632

Query: 676  ASSSAADTN 684
            A SS   T+
Sbjct: 1633 APSSTPGTS 1641



 Score = 57.4 bits (137), Expect = 8e-08
 Identities = 112/438 (25%), Positives = 156/438 (35%), Gaps = 75/438 (17%)

Query: 277  PANGSAP-----SAPAQPPCFHLALPQNSPSPAAGQPVTVAQGAPGSLTHSPPAAGQSHM 331
            PA  SAP     SAP        AL  +   P A  PV  A   P SL  S  +   S +
Sbjct: 1448 PAPASAPLTIPISAPLTVSASGPALLTSVTPPLA--PVVPAAPGPPSLAPSGASPSASAL 1505

Query: 332  TLVSSPLPVGQNSLTLQPPAPQPVFLSHGVPLHQSVNPPVLPLSQPVGPVNKSVGTSVLP 391
            TL  +  P   +S T   P       SH   L+ +V P   P+  P      S   S  P
Sbjct: 1506 TLGLATAPSLSSSQTPGHPLLLAPTSSHVPGLNSTVAPACSPVLVPA-----SALASPFP 1560

Query: 392  INQTVRPGVLPLTQPVGPINR----PVGPGVLP--------VSPSVTPGVLQAVSPGVLS 439
                  P    L  P    ++    P+ P   P         +P + P  + A SPG   
Sbjct: 1561 SAPNPAPAQASLLAPASSASQALATPLAPMAAPQTAILAPSPAPPLAPLPVLAPSPGAAP 1620

Query: 440  V--SRAVPSGVLPAGQMTPAGQMTPAGVIPGQTATSGVLPTGQMVQSGV---LPVGQTAP 494
            V  S   P  V+ A   TP   +  A  +P  T       T  M+ + V   LP   +  
Sbjct: 1621 VLASSQTPVPVM-APSSTPGTSLASASPVPAPTPVLAPSSTQTMLPAPVPSPLPSPASTQ 1679

Query: 495  SRVLPP------GQTAPLRVISAGQVVPSGLLSPNQTVS---SSAVVPVNQGVNSGVLQL 545
            +  L P      G ++P + +S G   P G   P QT+S   +S++VP            
Sbjct: 1680 TLALAPALAPTLGGSSPSQTLSLGTGNPQGPF-PTQTLSLTPASSLVPT----------- 1727

Query: 546  SQPVVSGVLPVGQPVRPGVLQLNQTVGTNILPVNQPVRPGASQNTTFLTSGSILRQLIPT 605
              P  +  L  G P+ P    L+      + P + PV P  +   T   + S    L P 
Sbjct: 1728 --PAQTLSLAPGPPLGP-TQTLSLAPAPPLAPAS-PVGPAPAHTLTLAPASSSASLLAPA 1783

Query: 606  GKQ---VNGIPTYTLAPVSV-TLPVPPGGLATVAPPQMPIQLLPSGAA---APMAGSMP- 657
              Q   ++  P  TL P +  TL + P    + A     + +  SGAA     M   +P 
Sbjct: 1784 SVQTLTLSPAPVPTLGPAAAQTLALAPASTQSPASQASSLVVSASGAAPLPVTMVSRLPV 1843

Query: 658  ------------GMPSPP 663
                        G PSPP
Sbjct: 1844 SKDEPDTLTLRSGPPSPP 1861



 Score = 52.0 bits (123), Expect = 3e-06
 Identities = 89/363 (24%), Positives = 139/363 (38%), Gaps = 60/363 (16%)

Query: 349  PPAPQPVFLS-----HGVPLHQS-----VNPPVLPL--------------SQPV-GPVNK 383
            PP P+PV +        VP  +      VN P  PL              +QP  GPV +
Sbjct: 984  PPRPKPVKMKVNRMLQPVPKQEGRTVVVVNNPRAPLGPVPVRPPPGPELSAQPTPGPVPQ 1043

Query: 384  SVGTSVLPINQTVRPGVLPLTQPVGPI-------NRPVGPGVLPVSPSVTPGVLQAVSPG 436
             +  S++       P ++P ++P GP+       N    P VLP    V  G  +  +P 
Sbjct: 1044 VLPASLMVSASPAGPPLIPASRPPGPVLLPPLQPNSGSLPQVLPSPLGVLSGTSRPPTPT 1103

Query: 437  V-LSVSRAVPSGVLPAGQMTPAGQMTPAGVIPGQT----ATSGVLPTGQMVQSGVLPVGQ 491
            + L  +   P  + PA     +  + P  V PG T    A +    T     +  +P   
Sbjct: 1104 LSLKPTPPAPVRLSPAPPPGSSSLLKPLTVPPGYTFPPAAATTTSTTTATATTTAVPAPT 1163

Query: 492  TAPSR-VLPPGQTAPL---RVISAGQVVPSGLLSPNQTVSSSAVVPVNQGVNSGVLQLSQ 547
             AP R +L P   A L    V+S GQ+     L+     ++    P+   +    L L+ 
Sbjct: 1164 PAPQRLILSPDMQARLPSGEVVSIGQLAS---LAQRPVANAGGSKPLTFQIQGNKLTLTG 1220

Query: 548  PVVSGVLPVGQ--PVRPGVLQLNQTVGTNILPVNQPVRPGASQNTTFLTSGSILRQLIPT 605
              V   L VGQ  P++  V+ L    G + L ++QP      Q     T G     ++P 
Sbjct: 1221 AQVR-QLAVGQPRPLQRNVVHLVSAGGQHHL-ISQPAHVALIQ-AVAPTPGPTPVSVLP- 1276

Query: 606  GKQVNGIPTYTLAPVSVTLP-----VPPGGLATVAPPQMPIQLLPSGAAAPMAGSMPGMP 660
                +  P+ T AP  ++LP     VPP  +      ++ ++  P     P+    P  P
Sbjct: 1277 ----SSTPSTTPAPTGLSLPLAANQVPPTMVNNTGVVKIVVRQAPRDGLTPVPPLAPA-P 1331

Query: 661  SPP 663
             PP
Sbjct: 1332 RPP 1334



 Score = 45.4 bits (106), Expect = 3e-04
 Identities = 105/445 (23%), Positives = 156/445 (35%), Gaps = 74/445 (16%)

Query: 277  PANGSAPSAPAQPPCFHLALPQN---SPSPAAGQPVTVAQGAPGSLTHSP--PAAGQSHM 331
            P  G   SA   P      LP +   S SPA G P+  A   PG +   P  P +G    
Sbjct: 1026 PPPGPELSAQPTPGPVPQVLPASLMVSASPA-GPPLIPASRPPGPVLLPPLQPNSGSLPQ 1084

Query: 332  TLVSSPLPVGQNSLTLQPPAPQPVFLSHGVPLHQSVNPPVLPLSQPVGPVNKSVGTSVLP 391
             L   P P+G  S T +PP P          L     PP      P  P     G+S L 
Sbjct: 1085 VL---PSPLGVLSGTSRPPTP---------TLSLKPTPPAPVRLSPAPP----PGSSSLL 1128

Query: 392  INQTVRPGVLPLTQPVGPINRPVGPGVLPVSPSVTPGVLQAV-SPGVLSVSRAVPSGVLP 450
               TV PG           +           P+ TP   + + SP +           LP
Sbjct: 1129 KPLTVPPGYTFPPAAATTTSTTTATATTTAVPAPTPAPQRLILSPDM--------QARLP 1180

Query: 451  AGQMTPAGQMTPAGVIPGQTATSGVLPTGQMVQSGVLPVGQTAPSRVLPPGQTAPLR--- 507
            +G++   GQ+      P   A  G  P    +Q   L +   A  R L  GQ  PL+   
Sbjct: 1181 SGEVVSIGQLASLAQRPVANA-GGSKPLTFQIQGNKLTL-TGAQVRQLAVGQPRPLQRNV 1238

Query: 508  --VISAG----------QVVPSGLLSPNQTVSSSAVVPVN-QGVNSGVLQLSQPVVSGVL 554
              ++SAG           V     ++P    +  +V+P +          LS P+ +  +
Sbjct: 1239 VHLVSAGGQHHLISQPAHVALIQAVAPTPGPTPVSVLPSSTPSTTPAPTGLSLPLAANQV 1298

Query: 555  PVGQPVRPGVLQL--NQTVGTNILPVNQPVRPGASQNTTFLTSGSILRQLIPTGKQVNGI 612
            P       GV+++   Q     + PV  P+ P     ++ L +    R  +  G+    +
Sbjct: 1299 PPTMVNNTGVVKIVVRQAPRDGLTPV-PPLAPAPRPPSSGLPAVLNPRPTLTPGR----L 1353

Query: 613  PTYTLAPVSVTLPV-------------PPGGLATVAPPQMPIQL-----LPSGAAAPMAG 654
            PT TL      +P              P   ++  AP   P+ +     +PS    P + 
Sbjct: 1354 PTPTLGTARAPMPTPTLVRPLLKLVHSPSPEVSASAPGAAPLTISSPLHVPSSLPGPASS 1413

Query: 655  SMPGMPSPPVLVNAAQSVFVQASSS 679
             MP   S P+    + +V V  SSS
Sbjct: 1414 PMPIPNSSPLASPVSSTVSVPLSSS 1438



 Score = 44.3 bits (103), Expect = 7e-04
 Identities = 76/283 (26%), Positives = 112/283 (39%), Gaps = 34/283 (12%)

Query: 266  IAPKPAAHLA-----APANGSAP-SAPAQPPCFHLALPQNSPSPAAGQPVTVAQGAPGSL 319
            +AP PA  LA     AP+ G+AP  A +Q P     +P  +PS   G  +  A   P   
Sbjct: 1598 LAPSPAPPLAPLPVLAPSPGAAPVLASSQTP-----VPVMAPSSTPGTSLASASPVPAPT 1652

Query: 320  THSPPAAGQSHMTL-VSSPLPVGQNSLTLQ-PPAPQPVF--LSHGVPLHQSVNPPVLPLS 375
                P++ Q+ +   V SPLP   ++ TL   PA  P     S    L      P  P  
Sbjct: 1653 PVLAPSSTQTMLPAPVPSPLPSPASTQTLALAPALAPTLGGSSPSQTLSLGTGNPQGPF- 1711

Query: 376  QPVGPVNKSVGTSVLPI-NQTVRPGVLPLTQPVGPINRPVGPGVLPVSP-SVTPGVLQAV 433
             P   ++ +  +S++P   QT+     P   P   ++    P + P SP    P     +
Sbjct: 1712 -PTQTLSLTPASSLVPTPAQTLSLAPGPPLGPTQTLSLAPAPPLAPASPVGPAPAHTLTL 1770

Query: 434  SPGVLSVSRAVPSGV-------LPAGQMTPAGQMTPAGVIPGQTATSGVLPTGQMVQ-SG 485
            +P   S S   P+ V        P   + PA   T A + P  T +     +  +V  SG
Sbjct: 1771 APASSSASLLAPASVQTLTLSPAPVPTLGPAAAQTLA-LAPASTQSPASQASSLVVSASG 1829

Query: 486  VLPVGQTAPSRVLPPGQTAPLRVISAGQVVPSGLLSPNQTVSS 528
              P+  T  SR LP  +  P  +      + SG  SP  T +S
Sbjct: 1830 AAPLPVTMVSR-LPVSKDEPDTL-----TLRSGPPSPPSTATS 1866



 Score = 42.4 bits (98), Expect = 0.003
 Identities = 105/439 (23%), Positives = 157/439 (35%), Gaps = 73/439 (16%)

Query: 259  GLLKQTHIAPKPAAHLAAPANGSAPSAPAQPPCFHLALPQNSPSPAAGQPVTVAQG---A 315
            G+L  T   P P   L          +PA PP           S +  +P+TV  G    
Sbjct: 1091 GVLSGTSRPPTPTLSLKPTPPAPVRLSPAPPP----------GSSSLLKPLTVPPGYTFP 1140

Query: 316  PGSLTHSPPAAGQSHMTLVSSPLPVGQNSLTLQPPAPQPVFLSHGVPLHQSVNPPVLPLS 375
            P + T +      +  T V +P P  Q  L L P     +     V + Q  +    P++
Sbjct: 1141 PAAATTTSTTTATATTTAVPAPTPAPQR-LILSPDMQARLPSGEVVSIGQLASLAQRPVA 1199

Query: 376  QPVG--PVNKSV-GTSVLPINQTVRPGVLPLTQPVGPINRPV------GPGVLPVSPSVT 426
               G  P+   + G  +      VR   L + QP  P+ R V      G     +S    
Sbjct: 1200 NAGGSKPLTFQIQGNKLTLTGAQVRQ--LAVGQP-RPLQRNVVHLVSAGGQHHLISQPAH 1256

Query: 427  PGVLQAVSPGVLSVSRAVPSGVLPAGQMTPAGQMTPAG---------VIPGQTATSGVLP 477
              ++QAV+P         P  VLP+   TP+    P G         V P     +GV+ 
Sbjct: 1257 VALIQAVAP----TPGPTPVSVLPSS--TPSTTPAPTGLSLPLAANQVPPTMVNNTGVVK 1310

Query: 478  --TGQMVQSGVLPVGQTAPSRVLPPGQTAPLRVISAGQVVPSGLLSPNQ-TVSSSAVVPV 534
                Q  + G+ PV   AP+   PP    P  +     + P  L +P   T  +    P 
Sbjct: 1311 IVVRQAPRDGLTPVPPLAPAP-RPPSSGLPAVLNPRPTLTPGRLPTPTLGTARAPMPTPT 1369

Query: 535  NQGVNSGVLQLSQPVVSGVLPVGQPVRPGVLQLNQTVGTNILPVNQPVR-PGASQNTTFL 593
                   ++    P VS   P   P+            T   P++ P   PG + +   +
Sbjct: 1370 LVRPLLKLVHSPSPEVSASAPGAAPL------------TISSPLHVPSSLPGPASSPMPI 1417

Query: 594  TSGSILRQLIPTGKQVNGIPTYTLAPVSV--TLPVPPGGLATVAPPQMPIQLLPSGAA-- 649
             + S L    P    V+ +P  +  P+SV  TLP P     T+ P   P+ +  SG A  
Sbjct: 1418 PNSSPLAS--PVSSTVS-VPLSSSLPISVPTTLPAPASAPLTI-PISAPLTVSASGPALL 1473

Query: 650  -------APMAGSMPGMPS 661
                   AP+  + PG PS
Sbjct: 1474 TSVTPPLAPVVPAAPGPPS 1492



 Score = 31.6 bits (70), Expect = 4.5
 Identities = 60/250 (24%), Positives = 89/250 (35%), Gaps = 46/250 (18%)

Query: 265  HIAPKPAAHLAAPANG---SAPSAPAQPPCFHLAL---------PQNSPSPAAGQPVTVA 312
            H  P     L  P++      PS P      +L L          Q   SP + +  +VA
Sbjct: 2511 HTPPPAQTCLVTPSSPLLLGPPSVPISASVTNLPLGLRPEAELCAQALASPESLELASVA 2570

Query: 313  QGAPGSLTHSPPAAGQSHMTLVSSPLPVGQNSLTLQPPAPQPVFLSHGVPLHQSVNPP-- 370
                 SL+  PP   +  + +    LPV + +L+L P AP     +  +P  Q    P  
Sbjct: 2571 SSETSSLSLVPP---KDLLPVAVEILPVSEKNLSLTPSAPSLTLEAGSIPNGQEQEAPDS 2627

Query: 371  -------VLPLSQPVG-PVNKSVGTSVLPINQTVRPGVLP---------LTQPVGPINRP 413
                   VLP  + +   V++S G  + P   +  P   P         LT+   P + P
Sbjct: 2628 AEGTTLTVLPEGEELPLCVSESNGLELPPSAASDEPLQEPLEADRTSEELTEAKTPTSSP 2687

Query: 414  VGPGVLPVSPSVTPGVLQAVSPGVLSVSRAVPSGVLPAGQMTPAGQMTPAGV-IPGQTAT 472
              P  L  +        +  +P   S + + P G  PA    P  + T A V I GQ   
Sbjct: 2688 EKPQELVTA--------EVAAPSTSSSATSSPEGPSPA---RPPRRRTSADVEIRGQGTG 2736

Query: 473  SGVLPTGQMV 482
                P G  V
Sbjct: 2737 RPGQPPGPKV 2746


>gi|160707881 formin 2 [Homo sapiens]
          Length = 1722

 Score = 66.6 bits (161), Expect = 1e-10
 Identities = 99/422 (23%), Positives = 138/422 (32%), Gaps = 57/422 (13%)

Query: 268  PKPAAHLAAPANGSAPSAPAQPPCFHLALPQNSPSPAAGQPVTVAQGAPGSLTHSPPAAG 327
            P  A     P  G+    P  PP     +P   P P AG  +      PG+    PP   
Sbjct: 892  PSTAIPQPPPLQGTEMLPPPPPPLPGAGIPPPPPLPGAG--ILPLPPLPGAGIPPPP--- 946

Query: 328  QSHMTLVSSPLPVGQNSLTLQPPAPQPVFLSHGVPLHQSVNPPVLPLSQPVGPVNKSVGT 387
                     PLP       + PP P P     G+PL     PP LP    + P     G 
Sbjct: 947  ---------PLP----GAAIPPPPPLP---GAGIPL-----PPPLP-GAGIPPPPPLPGA 984

Query: 388  SVLPINQTVRPGVLPLTQPVGPINRPVGPGVLPVSPSVTPGVLQAVSPGVLSVSRAVPSG 447
             + P       G+ P      P   P G G+ P  P    G+     P  L  +   P  
Sbjct: 985  GIPPPPPLPGAGIPP------PPPLP-GAGIPPPPPLPGAGI---PPPPPLPGAGIPPPP 1034

Query: 448  VLPAGQMTPAGQMTPAGVIPGQTATSGVLPTGQMVQSGVLPVGQTAPSRVLPPGQTAPLR 507
             LP   + P   +  AG+ P        +P    +    +P     P   +PP    P  
Sbjct: 1035 PLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGA 1094

Query: 508  VISAGQVVPSGLLSPNQTVSSSAVVPVNQGVNSGVLQLSQPVVSGVLPVGQPVRPGVLQL 567
             I     +P   + P   +  + + P      +G+        +G+ P     R G+   
Sbjct: 1095 GIPPPPPLPGVGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPRVGIPPP 1154

Query: 568  NQTVGTNILPVNQPVRPGASQNTTFLTSGSILRQLIPTGKQVNGI---PTYTLAPVSVTL 624
                G  I P   P  PGA                IP    + G+   P   L  V +  
Sbjct: 1155 PPLPGAGIPP--PPPLPGAG---------------IPPPPPLPGVGIPPPPPLPGVGIPP 1197

Query: 625  PVPPGGLATVAPPQMPIQLLPSGAAAPMAGSMPGMPSPPVLVNAAQSVFVQASSSAADTN 684
            P P  G     PP +P   +P   A P+     G+P PP+L  +   +  Q  SS   T 
Sbjct: 1198 PPPLPGAGIPPPPPLPGMGIPPAPAPPLPPPGTGIPPPPLLPVSGPPLLPQVGSSTLPTP 1257

Query: 685  QV 686
            QV
Sbjct: 1258 QV 1259


>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo
           sapiens]
          Length = 1124

 Score = 65.1 bits (157), Expect = 4e-10
 Identities = 113/439 (25%), Positives = 160/439 (36%), Gaps = 63/439 (14%)

Query: 268 PKPAAHLAAPA----NGSAPSAPAQPPCFHLA--LPQNSPSPAA--------GQPVTVAQ 313
           P P+   A P     N + P     PP   LA  LP   PSP+A          P T   
Sbjct: 307 PSPSGTKARPVPPPDNAATPLPATLPPSPPLATPLPLAPPSPSAPPSLQTLPSPPATPPS 366

Query: 314 GAPGSLTHSPPAAGQSHMTLVSSPLPVGQNSLTLQPPAPQPVFLSHGVPLHQSVNPPVLP 373
            AP S+T  P  A  S  T+    +P    S +LQ P P P+ LS  +    S+  P L 
Sbjct: 367 QAPPSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQAP-PSPLALS-SLQATTSLGSPTLQ 424

Query: 374 LSQP---VGPVNKSVGTSVLPINQTVRPGVLPLTQPVG-----PINRPVGPGVLPVSPSV 425
            +     + P       +      +  P   PL  P+      P+   + P V P+S  +
Sbjct: 425 ATHSFLTMSPRQTQASLTSPSRPASTPPDSPPLQAPLSLPASPPLQTSLSPAVSPLSSPL 484

Query: 426 TPGVLQAVSPGVLSVSRAVPSGVLPAGQMTPAGQMTPAGVIPGQTATSGVLPTGQMVQSG 485
           T   LQA+S       +A  S ++     T +    P+   P  + T+   P  + + S 
Sbjct: 485 TIHPLQALSSLASHSPQAPLSSLIMPPLETQSSLAPPSLQTPPASLTT---PPLENLPSL 541

Query: 486 VLPVGQTAPSRVLPPG-QTAPLRVISAGQVVPSGLLSPNQTVSSSAVVPVNQGVNSGVLQ 544
             P  QTA + +  P  +T P       Q  PS L +P     SS   P  Q   +    
Sbjct: 542 APPPLQTASAPLTTPHLETPPCPAPCPLQAPPSPLTTPPPETPSSIATPPPQAPPA---- 597

Query: 545 LSQPVVSGV-------LPVGQPVRPGVLQLNQTVGTNILPVNQPVRPGASQNTTFLTSGS 597
           L+ P + G+       L    P  P  L L         P+  P  P AS   + L +  
Sbjct: 598 LASPPLQGLPSPPLSPLATPPPQAPPXLALP--------PLQAPPSPPASPPLSPLAT-- 647

Query: 598 ILRQLIPTGKQVNGIPTYTL-APVS------VTLPVPPGGLATVAPPQMPIQLLPSGAAA 650
                 P+ +  N +  + L AP S      V  P  P     V+P   P    P   AA
Sbjct: 648 ------PSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAA 701

Query: 651 PMAGSMPGMP-SPPVLVNA 668
           P     P  P SPP+  +A
Sbjct: 702 PPLQVPPSPPASPPMSPSA 720



 Score = 60.1 bits (144), Expect = 1e-08
 Identities = 108/433 (24%), Positives = 145/433 (33%), Gaps = 85/433 (19%)

Query: 268 PKPAAHLAAPANGSAPSAPAQPPCFHLALP-------------QNSPSPAA--GQPVTVA 312
           P P A   + A  S  + P Q P     +P             Q  PSP A      T +
Sbjct: 358 PSPPATPPSQAPPSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQAPPSPLALSSLQATTS 417

Query: 313 QGAPG-SLTHS----PPAAGQSHMTLVSSPLPVGQNSLTLQPPAPQPVFLSHGVPLHQSV 367
            G+P    THS     P   Q+ +T  S P     +S    PP   P+ L    PL  S+
Sbjct: 418 LGSPTLQATHSFLTMSPRQTQASLTSPSRPASTPPDS----PPLQAPLSLPASPPLQTSL 473

Query: 368 NPPVLPLSQP--VGPV----NKSVGTSVLPINQTVRPGVLPLTQPVGPINRPVGPGVLPV 421
           +P V PLS P  + P+    + +  +   P++  + P  L     + P +    P  L  
Sbjct: 474 SPAVSPLSSPLTIHPLQALSSLASHSPQAPLSSLIMP-PLETQSSLAPPSLQTPPASLTT 532

Query: 422 S-----PSVTPGVLQAVSPGVLSVSRAVPSGVLPAGQMTPAGQMTPAGVIPGQTATSGVL 476
                 PS+ P  LQ  S  + +     P    P     P   +T     P +T +S   
Sbjct: 533 PPLENLPSLAPPPLQTASAPLTTPHLETPPCPAPCPLQAPPSPLTTP---PPETPSSIAT 589

Query: 477 PTGQMVQSGVLPVGQTAPSRVL-----PPGQTAPLRVISAGQVVPSGLLSPNQTVSSSAV 531
           P  Q   +   P  Q  PS  L     PP Q  P   +   Q  PS   SP     S   
Sbjct: 590 PPPQAPPALASPPLQGLPSPPLSPLATPPPQAPPXLALPPLQAPPSPPASP---PLSPLA 646

Query: 532 VPVNQGVNSGVLQLSQPVVSGVLPVGQPVRPGVLQLNQTVGTNILPVNQPVRPGASQNTT 591
            P  Q  N+  + L Q       P   P  P              PV  P  P AS   +
Sbjct: 647 TPSPQAPNALAVHLLQ------APFSPPPSP--------------PVQAPFSPPASPPVS 686

Query: 592 FLTSGSILRQLIPTGKQVNGIPTYTLAPVSVTLPVPPGGLATVAPPQMPIQLLPSGAAAP 651
                       P+    +  P    AP     P PP      +PP  P    P  A  P
Sbjct: 687 ------------PSATPPSQAPPSLAAPPLQVPPSPP-----ASPPMSPSATPPPQAPPP 729

Query: 652 MAG-SMPGMPSPP 663
           +A   +   PSPP
Sbjct: 730 LAAPPLQVPPSPP 742



 Score = 57.0 bits (136), Expect = 1e-07
 Identities = 111/437 (25%), Positives = 151/437 (34%), Gaps = 68/437 (15%)

Query: 274 LAAPANGSAPSAPAQPPCFHLALPQN----SPSPAAGQPVTVAQGAPGSLTHSPPAAGQS 329
           L  PA  + P  P + P   ++         PSPAA +       A G L      +  S
Sbjct: 189 LPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARR----RPSAGGGLQRPASRSLSS 244

Query: 330 HMTLVSSPLPVGQNS-----LTLQPPAPQPVFLSHGVPLHQSVNPPVLPLSQPVGPVNKS 384
             T +SSP   G ++         P  P+P  L    P    V PP    +  +GP++ S
Sbjct: 245 SATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRP--PQVTPPRKDAAPALGPLSSS 302

Query: 385 VGTSVLPINQTVRP--------GVLPLTQPVGPINRPVGPGVLPVSPSVTPGVLQAVSPG 436
              +  P     RP          LP T P  P      P + P SPS  P +    SP 
Sbjct: 303 PLATPSPSGTKARPVPPPDNAATPLPATLPPSPPLATPLP-LAPPSPSAPPSLQTLPSPP 361

Query: 437 VLSVSRAVPSGVLPAGQMTPAGQMTPAGVIPG-------------------QTATSGVLP 477
               S+A PS   P  Q  P+ Q  P   +P                    Q  TS   P
Sbjct: 362 ATPPSQAPPSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQAPPSPLALSSLQATTSLGSP 421

Query: 478 TGQMVQSGVLPVGQTAPSRVLPPGQTAPLRVISAGQVVPSGLLS--PNQTVSSSAVVPVN 535
           T Q   S +    +   + +  P + A     S     P  L +  P QT  S AV P++
Sbjct: 422 TLQATHSFLTMSPRQTQASLTSPSRPASTPPDSPPLQAPLSLPASPPLQTSLSPAVSPLS 481

Query: 536 QGVNSGVLQLSQPVVSGV--LPVGQPVRPGVLQLNQTVGTNILPVNQPVRPGASQNTTFL 593
             +    LQ    + S     P+   + P +    +T  +   P  Q   P AS  T  L
Sbjct: 482 SPLTIHPLQALSSLASHSPQAPLSSLIMPPL----ETQSSLAPPSLQT--PPASLTTPPL 535

Query: 594 TSGSILRQLIPTGKQVNGIPTYTL------APVSVTLPVPPGGLATVAPPQMPIQLLPSG 647
            +   L  L P   Q    P  T        P    L  PP  L T  PP+ P     S 
Sbjct: 536 EN---LPSLAPPPLQTASAPLTTPHLETPPCPAPCPLQAPPSPLTT-PPPETP-----SS 586

Query: 648 AAAPMAGSMPGMPSPPV 664
            A P   + P + SPP+
Sbjct: 587 IATPPPQAPPALASPPL 603



 Score = 55.8 bits (133), Expect = 2e-07
 Identities = 100/407 (24%), Positives = 138/407 (33%), Gaps = 87/407 (21%)

Query: 274 LAAPANGSAPSAPAQPPCFHLALPQNSPSPAAGQPVTVAQGAPGSLTHSPPAAGQSHMTL 333
           LA P+  + P++   PP  +L      P   A  P+T           +PP      +  
Sbjct: 518 LAPPSLQTPPASLTTPPLENLPSLAPPPLQTASAPLTTPH------LETPPCPAPCPLQA 571

Query: 334 VSSPL----PVGQNSLTLQPPAPQPVFLSHGVPLHQSVNPPVLPLSQPVGPVNKSVGTSV 389
             SPL    P   +S+   PP   P   S   PL    +PP+ PL+ P  P       ++
Sbjct: 572 PPSPLTTPPPETPSSIATPPPQAPPALASP--PLQGLPSPPLSPLATP--PPQAPPXLAL 627

Query: 390 LPINQTVRPGVLPLTQPVGPINRPV--GPGVL-------PVSPSVTPGVLQAVSPGVLSV 440
            P+     P   P + P+ P+  P    P  L       P SP  +P V    SP     
Sbjct: 628 PPLQAPPSP---PASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSP---PA 681

Query: 441 SRAVPSGVLPAGQMTPAGQMTPAGVIPGQTATSGVLPTGQMVQSGVLPVGQTAPSRVLPP 500
           S  V     P  Q  P+    P  V P   A+  + P+             T P +  PP
Sbjct: 682 SPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSA------------TPPPQAPPP 729

Query: 501 GQTAPLRVISAGQVVPSGLLSPNQTVSSSAVVPVNQGVNSGVLQL--SQPVVSGVLPVGQ 558
               PL      QV PS   SP  + S++    V   + +  LQ+  S P    + P+ +
Sbjct: 730 LAAPPL------QVPPSPPASPPMSPSATPPPRVPPLLAAPPLQVPPSPPASLPMSPLAK 783

Query: 559 PVRPGVLQLNQTVGTNILPVNQPVRPGASQNTTFLTSGSILRQLIPTGKQVNGIPTYTLA 618
           P  P       T     LP      PG                                A
Sbjct: 784 PP-PQAPPALATPPLQALPSPPASFPGQ-------------------------------A 811

Query: 619 PVSVTLPVPPGGLATVAPPQMPIQLLPSGAAAPMAGSMPGMPSPPVL 665
           P S +  +P   LAT  PPQ P  L     AAP+    P  P+ P L
Sbjct: 812 PFSPSASLPMSPLAT-PPPQAPPVL-----AAPLLQVPPSPPASPTL 852



 Score = 45.8 bits (107), Expect = 2e-04
 Identities = 70/246 (28%), Positives = 94/246 (38%), Gaps = 29/246 (11%)

Query: 261 LKQTHIAPKPAAHLAAPANGSAPSAPAQPPCFHLALPQNSPSPA-AGQPVTVAQGAPGSL 319
           L Q   +P P+  + AP      S PA PP    A P +   P+ A  P+ V    P S 
Sbjct: 660 LLQAPFSPPPSPPVQAPF-----SPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASP 714

Query: 320 THSPPAA--GQSHMTLVSSPLPVGQNSLTLQPPAPQPVFLSHGVPLHQSVNPPVL---PL 374
             SP A    Q+   L + PL V  +     PPA  P+  S   P      PP+L   PL
Sbjct: 715 PMSPSATPPPQAPPPLAAPPLQVPPS-----PPASPPMSPSATPPPRV---PPLLAAPPL 766

Query: 375 SQPVGPVNKSVGTSVLPINQTVRPGVLPLTQPVGPINRPVG--PGVLPVSPSVTPGVLQA 432
             P  P   S+  S L       P  L  T P+  +  P    PG  P SPS +      
Sbjct: 767 QVPPSP-PASLPMSPLAKPPPQAPPAL-ATPPLQALPSPPASFPGQAPFSPSAS----LP 820

Query: 433 VSPGVLSVSRAVPSGVLPAGQMTPAGQMTPAGVIPGQTATSG--VLPTGQMVQSGVLPVG 490
           +SP      +A P    P  Q+ P+   +P    P +  T G     +G  +   + P  
Sbjct: 821 MSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGP 880

Query: 491 QTAPSR 496
              PSR
Sbjct: 881 PPPPSR 886



 Score = 45.8 bits (107), Expect = 2e-04
 Identities = 58/198 (29%), Positives = 77/198 (38%), Gaps = 13/198 (6%)

Query: 274 LAAPANGSAPSAPAQPPCFHLAL-PQNSPSPAAGQPVTVAQGAPGSLTHSPPAAGQSHM- 331
           LAAP     PS PA PP    A  P  +P P A  P+ V    P S   SP A     + 
Sbjct: 699 LAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQVPPSPPASPPMSPSATPPPRVP 758

Query: 332 -TLVSSPLPVGQN---SLTLQP---PAPQPVFLSHGVPLHQSVNPPV-LPLSQPVGPVNK 383
             L + PL V  +   SL + P   P PQ        PL    +PP   P   P  P + 
Sbjct: 759 PLLAAPPLQVPPSPPASLPMSPLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSP-SA 817

Query: 384 SVGTSVLPINQTVRPGVLPLTQPVGPINRPVGPGVLPVSPSVTPGVLQAVSPGVLSVSRA 443
           S+  S L       P VL       P + P  P +       TPG   +VS   L++  A
Sbjct: 818 SLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTL--A 875

Query: 444 VPSGVLPAGQMTPAGQMT 461
           +  G  P    +P+  ++
Sbjct: 876 LAPGPPPPPSRSPSSTLS 893



 Score = 43.1 bits (100), Expect = 0.001
 Identities = 54/205 (26%), Positives = 74/205 (36%), Gaps = 25/205 (12%)

Query: 268 PKPAAHLAAPANGSAPSAPAQPPCFHLAL-PQNSPSPAAGQPVTVAQGAPGSLTHSPPAA 326
           P+    LAAP     PS PA PP    A  P   P   A  P+ V    P SL  SP   
Sbjct: 724 PQAPPPLAAPPLQVPPSPPASPPMSPSATPPPRVPPLLAAPPLQVPPSPPASLPMSP--- 780

Query: 327 GQSHMTLVSSPLPVGQNSLTLQP----PAPQPVFLSHGVPLHQSVNPPVLPLSQPVGPVN 382
                  ++ P P    +L   P    P+P P       P   S + P+ PL+ P     
Sbjct: 781 -------LAKPPPQAPPALATPPLQALPSP-PASFPGQAPFSPSASLPMSPLATPPPQAP 832

Query: 383 KSVGTSVLPINQTVRPGVLPLTQPVGPINRPVGPGVLPVSPSVTPGVLQAVSPGVLSVSR 442
             +   +L +     P   P +  +    RP  PG  P +    P +  A++PG      
Sbjct: 833 PVLAAPLLQV-----PPSPPASPTLQAPRRPPTPG--PDTSVSGPRLTLALAPGPPPPPS 885

Query: 443 AVPSGVLPAGQMTPAGQMTPAGVIP 467
             PS  L    +  AG  + A   P
Sbjct: 886 RSPSSTLSGPDL--AGHSSSATSTP 908



 Score = 38.1 bits (87), Expect = 0.048
 Identities = 73/252 (28%), Positives = 91/252 (36%), Gaps = 27/252 (10%)

Query: 268 PKPAAHLAAPANGSAPSAPAQPPCFHLALPQNSPSPAAGQPVTVAQGAPGSLTHSPPAA- 326
           P+    LAAP     PS PA  P   LA P     PA   P       P     SPPA+ 
Sbjct: 755 PRVPPLLAAPPLQVPPSPPASLPMSPLAKPPPQAPPALATP-------PLQALPSPPASF 807

Query: 327 -GQSHMTLVSSPLPVGQNSLTLQPPAPQPVFLSHGVPLHQ-SVNPPVLP-LSQPVGPVNK 383
            GQ+  +  S+ LP+  + L   PP   PV      PL Q   +PP  P L  P  P   
Sbjct: 808 PGQAPFS-PSASLPM--SPLATPPPQAPPVL---AAPLLQVPPSPPASPTLQAPRRPPTP 861

Query: 384 SVGTSVLPINQTVRPGVLPLTQPV-GPINRPVGPGVLPVSPSV--TPGVLQAVSPGVLSV 440
              TSV     T+     P   P   P +   GP +   S S   TP  L+    G    
Sbjct: 862 GPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGG 921

Query: 441 SRAVPSGVLPAGQMTPAG-QMTPAGVIPGQTATSGVLP----TGQMVQSGVLPVGQT-AP 494
           + A P          PA     PA  +  + A    LP    TG     G+  + +T  P
Sbjct: 922 AAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPATGPGSADGLCTIYETEGP 981

Query: 495 SRVLP-PGQTAP 505
               P PG   P
Sbjct: 982 ESATPAPGALDP 993


>gi|163965366 nascent polypeptide-associated complex alpha subunit
            isoform a [Homo sapiens]
          Length = 2078

 Score = 64.7 bits (156), Expect = 5e-10
 Identities = 108/457 (23%), Positives = 151/457 (33%), Gaps = 76/457 (16%)

Query: 277  PANGSAPSAPAQPPCFHLALPQNSPSPAAGQPVTVAQGAPGSLTHSPPAAGQSHMTLVSS 336
            P++   P+ PA  P          PSP  G  +   +G P S    P +  ++  T V+ 
Sbjct: 1363 PSSKEGPTPPAATPSHKGGPAMTPPSPKRGPAIPSPKGDPTSPAVIPLSPKKAPATPVTR 1422

Query: 337  PLPVGQNSLTLQPPAPQPVFLSH---------GVPLHQSVNPPVLPLSQPVG----PVNK 383
                  +   L PPA  PV L           G     S   P LP   P      P  K
Sbjct: 1423 EGAATPSKGDLTPPAVTPVSLKKAPATSAPKGGPATPSSKGDPTLPAVTPPSPKEPPAPK 1482

Query: 384  SVGTSVLPINQTVRPGVLPLTQPVGPINRPVGPGVLPVSPSVTPGVLQA----VSPGVLS 439
             V TS  P      P          P+  P  P V+P SP   P    +    ++P    
Sbjct: 1483 QVATSSSPKKAPATP---------APMGAPTLPAVIPSSPKEVPATPSSRRDPIAPTATL 1533

Query: 440  VSRAVPS------GVLPAGQMTPAGQMTPAGVIPGQ--------------TATSGVLPTG 479
            +S+  P+       ++P     P+ + TPA   P +                T       
Sbjct: 1534 LSKKTPATLAPKEALIPPAMTVPSPKKTPAIPTPKEAPATPSSKEASSPPAVTPSTYKGA 1593

Query: 480  QMVQSGVLPVGQTAPS---RVLPPGQTAPLRVISAGQVVPSGL-LSPNQTVSSSAVVPVN 535
               +  ++P   T+PS      PP  T P          P G   SP  T SS    P +
Sbjct: 1594 PSPKELLIPPAVTSPSPKEAPTPPAVTPPSPEKGPATPAPKGTPTSPPVTPSSLKDSPTS 1653

Query: 536  QGVNSGVLQLSQPVVSGVLPV--GQPVRPGVLQLNQTVGTNILPVNQPVRPGASQNTTFL 593
                +  +  + P  S  LP   G      VL       T I  +  P R G     +  
Sbjct: 1654 PASVTCKMGATVPQASKGLPAKKGPTALKEVLVAPAPESTPI--ITAPTRKGPQTKKSSA 1711

Query: 594  TSGSILRQLIPTGKQVNGIPTYTLAPVSVTLPVPPGGLAT-------------VAPPQMP 640
            TS  I     P+ K  +  P  T+AP  + LPV      T             +APP+  
Sbjct: 1712 TSPPICPD--PSAKNGSKGPLSTVAPAPL-LPVQKDSSKTAKGKDASHSPKGPLAPPESK 1768

Query: 641  IQLLPSGAA------APMAGSMPGMPSPPVLVNAAQS 671
                 + AA       P + S+   PSPPV +  A S
Sbjct: 1769 ASTPLTAAAFEKVLPKPESASVSAAPSPPVSLPLAPS 1805



 Score = 64.3 bits (155), Expect = 6e-10
 Identities = 105/416 (25%), Positives = 133/416 (31%), Gaps = 81/416 (19%)

Query: 262  KQTHIAPKPAAHLAAPANGSAPSAPAQPPCFHLALPQNSPSPAAGQPVTVAQGAPGSLTH 321
            K+    P P    A+P+   AP+ PA  P          PSP  G      + AP     
Sbjct: 919  KKARATPAPKGIPASPSPKGAPTPPAATP----------PSPKGGPATPSPKWAP----- 963

Query: 322  SPPAAGQSHMTLVSSPLPVGQNSLTLQPPAPQPVFLSHGVPLHQSVNPPVLPLSQPVGPV 381
            +PPAA        + P P G       P  P P     G P   +  PP  P   P  P 
Sbjct: 964  TPPAA--------TPPSPKG------GPATPSP----KGAPTPPAATPP-SPKGGPATPS 1004

Query: 382  NKSVGT--SVLPINQTVRPGVLPLTQPVGPINRPVGPGVLPVSPSVTPGVLQAVSPGVLS 439
             K   T  +V P +    P   P      P      P   P SP  +P           +
Sbjct: 1005 PKGAPTPPAVTPPSPKGSPAATPF-----PKGASTPPAATPPSPKGSPAATPLPKGAPTT 1059

Query: 440  VSRAVPSGVLPAGQMTPA--GQMTPAGVIPGQTATSGVLPTGQMVQSGVLPVGQTAPS-- 495
             +  +PS     G  TP+  G  TP    P         P+    +   +P   T PS  
Sbjct: 1060 PAATLPSP--KGGPATPSLKGAPTPPAATPPSPKGGPATPS---PKGAPMPPAATPPSPK 1114

Query: 496  --RVLPPGQTAPLRVISAGQVVPSGLLS--PNQTVSSSAVVPVNQGVNSGVLQLSQPVVS 551
                 PP + AP    +       GL +  P    ++ A  P +     G L    P  +
Sbjct: 1115 GGLATPPHKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSP---KGGLATPPPKGA 1171

Query: 552  GVLPVGQPVRP-GVLQLNQTVGTNILPVNQPVRPGASQNTTFLTSGSILRQLIPTGKQVN 610
               P   P  P G L      G    P   P  P     T             P+ K   
Sbjct: 1172 PTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLAT-------------PSPK--- 1215

Query: 611  GIPTYTLAPVSVTLPVPPGGLATVAP---PQMPIQLLPSGAAAPMAGSMPGMPSPP 663
            G PT   A    T P P GGLAT +P   P  P    PS    P      G P+PP
Sbjct: 1216 GAPTTPAA----TPPSPKGGLATPSPKGAPTTPAATPPSPKGGPATPPPKGAPTPP 1267



 Score = 56.6 bits (135), Expect = 1e-07
 Identities = 97/422 (22%), Positives = 148/422 (35%), Gaps = 35/422 (8%)

Query: 268  PKPAAHLAAPANGSAPSAPAQPPCFHLALPQNSPSPAAGQPVTVAQGAPGSLTHSPPAAG 327
            P     LA P +  AP+     P      P  SP   A  P      +P     +PP  G
Sbjct: 1272 PSLKGGLATPPHKGAPNPAVVTPPSPKGGPATSPPKGAPTPPAATPPSPKGSPGTPPPKG 1331

Query: 328  QSHMTLVSSPLPVGQNSLTLQPPAPQPVFLSHGVPLHQSVNPPVLPLSQPVGPVNKSVGT 387
                  V+ P P G  +L    P+      S G P   S      P   P    +   G 
Sbjct: 1332 APTPPAVTPPSPKGTPTLPATTPS------SKGGPTTPSSKEGPTP---PAATPSHKGGP 1382

Query: 388  SVLPINQTVRPGV-LPLTQPVGPINRPVGPGVLPVSP-----SVTPGVLQAVSPGV--LS 439
            ++ P +    P +  P   P  P   P+ P   P +P     + TP       P V  +S
Sbjct: 1383 AMTPPSPKRGPAIPSPKGDPTSPAVIPLSPKKAPATPVTREGAATPSKGDLTPPAVTPVS 1442

Query: 440  VSRAVPSGVLPAGQMTPAGQMTPAGVIPGQTATSGVLPTG-QMVQSGVLPVGQTAPSRVL 498
            + +A  +     G  TP+ +  P   +P  T  S   P   + V +   P  + AP+   
Sbjct: 1443 LKKAPATSAPKGGPATPSSKGDP--TLPAVTPPSPKEPPAPKQVATSSSP--KKAPATPA 1498

Query: 499  PPG-QTAPLRVISAGQVVPSGLLSPNQTVSSSAVVPVNQGVNSGVLQLSQPVVSGVLPVG 557
            P G  T P  + S+ + VP+   S    ++ +A +   +      L   + ++   + V 
Sbjct: 1499 PMGAPTLPAVIPSSPKEVPATPSSRRDPIAPTATLLSKK--TPATLAPKEALIPPAMTVP 1556

Query: 558  QPVR-PGVLQLNQTVGTNILPVNQPVRPGASQNTTFLTSGSILRQLIPTGKQVNGIPTYT 616
             P + P +    +   T      +   P A   +T+  + S    LIP     +  P   
Sbjct: 1557 SPKKTPAIPTPKEAPATP--SSKEASSPPAVTPSTYKGAPSPKELLIPPA-VTSPSPKEA 1613

Query: 617  LAPVSVTLPVPPGGLATVAPPQMPIQLLPSGAAAPMAGSMPGMPSPPVLVNAAQSVFVQA 676
              P +VT P P  G AT AP   P     S    P   S+   P+ P  V       V  
Sbjct: 1614 PTPPAVTPPSPEKGPATPAPKGTP----TSPPVTP--SSLKDSPTSPASVTCKMGATVPQ 1667

Query: 677  SS 678
            +S
Sbjct: 1668 AS 1669



 Score = 55.8 bits (133), Expect = 2e-07
 Identities = 99/397 (24%), Positives = 138/397 (34%), Gaps = 55/397 (13%)

Query: 295  ALPQNSPSPAAGQPVTVAQGAPGSLTHSPPAAGQSHMTLVSSPLPVGQNSLTLQPPAPQP 354
            A P  S  PA   P T    +  + T SP   G   ++L     PV + +LT  P  P  
Sbjct: 647  AFPLESADPAGVAPTTAKGTSTYTTTASPFLEGT--VSLAPKNHPVKEGTLTTLPLVPTA 704

Query: 355  VFLSHGVPLHQSVNPPVLPLSQPV--GPVNKSVGTSVLPINQTVRPGVLPLTQPVGPINR 412
               S   P+  S      PL+  V    + KSV +  LP       G  P T+ V  I+ 
Sbjct: 705  ---SENCPVAPSPQNTCAPLATLVLAPEIPKSVPSPSLP-----PAGTPPGTKKVDGISH 756

Query: 413  PVGPGVLPVSPSVTP-------------GVLQ--AVSPGVLSVSRAVPSGVLPAGQMTPA 457
                  +  SP   P             G L   A SP  L VS + P    P  +   A
Sbjct: 757  TSALAPVASSPKECPTEDSGASATASSKGTLTYLADSPSPLGVSVS-PQTKRPPTKKGSA 815

Query: 458  GQMTPAGVI--PGQTATSGVLPTGQMVQSGVL--PVGQTAPSRVLPPGQTAPLRVISAGQ 513
            G  TP G +  P     +  LP   +   G    P    +P+   P G   P  V     
Sbjct: 816  GPDTPIGNLSSPVSPVEASFLPENSLSFQGSKDSPATTHSPTPPSPKGAPTPSAVTPLS- 874

Query: 514  VVPSGL-LSPNQTVSSSAV-VPVNQGVNSGVLQLSQPVVSGVLPVGQPVRPGVLQLNQTV 571
              P G+ L P +T + S V +P  +   +       P +S  +    P +       + +
Sbjct: 875  --PKGVTLPPKETPTPSVVNLPFPKEGPATPAPKQAPALS--MTSSSPKKARATPAPKGI 930

Query: 572  GTNILPVNQPVRPGASQNTTFLTSGSILRQLIPTGKQVNGIPTYTLAPVSVTLPVPPGGL 631
              +  P   P  P A+  +             P G      P +   P + T P P GG 
Sbjct: 931  PASPSPKGAPTPPAATPPS-------------PKGGPATPSPKWAPTPPAATPPSPKGGP 977

Query: 632  ATVAP---PQMPIQLLPSGAAAPMAGSMPGMPSPPVL 665
            AT +P   P  P    PS    P   S  G P+PP +
Sbjct: 978  ATPSPKGAPTPPAATPPSPKGGPATPSPKGAPTPPAV 1014



 Score = 53.5 bits (127), Expect = 1e-06
 Identities = 115/477 (24%), Positives = 161/477 (33%), Gaps = 104/477 (21%)

Query: 270 PAAHLAAPANGSAPSAPAQPPCFHLALPQNSPSP----AAGQPVTVA---------QGAP 316
           PAA + AP    AP  P+      L +P + P P        P +V          Q  P
Sbjct: 480 PAALVMAPV---APKEPSTQVATTLRIPVSPPLPDPEDLKNLPSSVLVKFPTQKDLQTVP 536

Query: 317 GSLTHSPPAAGQSHMTLVSSP--LPVGQNSLTLQPPAPQPVFLSHGVPLHQSVNPPVLPL 374
            SL  +P +  Q+ +T    P  LP+ Q +     P+ Q    S  +PL          L
Sbjct: 537 ASLEGAPFSPAQAGLTTKKDPTVLPLVQ-AAPKNSPSFQSTSSSPEIPLSPEATLAKKSL 595

Query: 375 SQPVGPVNKSVGTSVLPINQTVRPGVLPLTQPVGPINRPVGPGVLPVSPSVTPGVLQAVS 434
            +P+ P+ K   +   P+       V+      GP +     G L  S  +TP V     
Sbjct: 596 GEPL-PIGKPASSMTSPLGVNSSASVIKTDSYAGPDSA----GPLLKSSLITPTV----- 645

Query: 435 PGVLSVSRAVPSGVLPAGQMTPAGQMTPAGVIPGQTATSGVLPTGQMVQSGVL---PVGQ 491
                +  A P+GV P      +   T A   P    T  + P    V+ G L   P+  
Sbjct: 646 -AAFPLESADPAGVAPTTAKGTSTYTTTAS--PFLEGTVSLAPKNHPVKEGTLTTLPLVP 702

Query: 492 TA----PSRVLPPGQTAPLRVISAGQVVPSGLLSPNQTVS--------------SSAVVP 533
           TA    P    P    APL  +     +P  + SP+   +              +SA+ P
Sbjct: 703 TASENCPVAPSPQNTCAPLATLVLAPEIPKSVPSPSLPPAGTPPGTKKVDGISHTSALAP 762

Query: 534 V----------NQGVNS-----GVLQL--SQPVVSGVLPVGQPVRPGVLQLNQTVGTNIL 576
           V          + G ++     G L      P   GV    Q  RP   + +    T I 
Sbjct: 763 VASSPKECPTEDSGASATASSKGTLTYLADSPSPLGVSVSPQTKRPPTKKGSAGPDTPIG 822

Query: 577 PVNQPVRPGASQNTTFLTSGSILRQ---------LIPTGKQVNGIPT------------- 614
            ++ PV P      +FL   S+  Q           PT     G PT             
Sbjct: 823 NLSSPVSP---VEASFLPENSLSFQGSKDSPATTHSPTPPSPKGAPTPSAVTPLSPKGVT 879

Query: 615 ----YTLAPVSVTLPVPPGGLATVAPPQMPIQLLPSGA-----AAPMAGSMPGMPSP 662
                T  P  V LP P  G AT AP Q P   + S +     A P    +P  PSP
Sbjct: 880 LPPKETPTPSVVNLPFPKEGPATPAPKQAPALSMTSSSPKKARATPAPKGIPASPSP 936



 Score = 49.3 bits (116), Expect = 2e-05
 Identities = 103/420 (24%), Positives = 152/420 (36%), Gaps = 54/420 (12%)

Query: 262  KQTHIAPKPAAHLAAPANGSAPSAPAQPPCFHLALPQNSPSPAAGQPVTVAQGAPGSLTH 321
            KQ   +  P    A PA   AP+ PA  P    + P+  P+  + +   +A  A   L+ 
Sbjct: 1482 KQVATSSSPKKAPATPAPMGAPTLPAVIP----SSPKEVPATPSSRRDPIAPTAT-LLSK 1536

Query: 322  SPPAAGQSHMTLVSSPLPVGQNSLTLQPPAPQPVFLSHGVPLHQSVNPP-VLPLSQPVGP 380
              PA       L+   + V     T  P  P P          ++ +PP V P +    P
Sbjct: 1537 KTPATLAPKEALIPPAMTVPSPKKT--PAIPTPKEAPATPSSKEASSPPAVTPSTYKGAP 1594

Query: 381  VNKSV-----GTSVLPINQTVRPGVLPLTQPVGPINRPVGPGVLPVSPSVTPGVLQAVSP 435
              K +      TS  P      P V P +   GP      P   P SP VTP  L+    
Sbjct: 1595 SPKELLIPPAVTSPSPKEAPTPPAVTPPSPEKGPAT--PAPKGTPTSPPVTPSSLKDSPT 1652

Query: 436  GVLSVSRAVPSGVLPAGQMTPAGQMTPAGVIPGQTATSGVLPTGQMVQSGVLPVGQTAPS 495
               SV+  + + V  A +  PA +        G TA   VL       + ++    TAP+
Sbjct: 1653 SPASVTCKMGATVPQASKGLPAKK--------GPTALKEVLVAPAPESTPII----TAPT 1700

Query: 496  RVLPPGQ--TAPLRVISAGQVVPSGLLSPNQTVSSSAVVPVNQGVNSGVLQLSQPVVSGV 553
            R  P  +  +A    I       +G   P  TV+ + ++PV Q  +S   +      S  
Sbjct: 1701 RKGPQTKKSSATSPPICPDPSAKNGSKGPLSTVAPAPLLPV-QKDSSKTAKGKDASHSPK 1759

Query: 554  LPVGQPVRPGVLQLNQTVGTNILPVNQPVRPGASQNTTFLTSGSILRQLIPTGKQVNGIP 613
             P+  P       L       +LP  +      S + +   S  +   L P+       P
Sbjct: 1760 GPLAPPESKASTPLTAAAFEKVLPKPE------SASVSAAPSPPVSLPLAPS-------P 1806

Query: 614  TYTLAPVSVTLPVPPGGLATVAPPQMPI------QLLPSGAAAPMAGSMPGMPSPPVLVN 667
              TL P    LP  PG    +  P  P+      +LLP     P++G   G+P   VLVN
Sbjct: 1807 VPTLPPKQQFLPSSPG--LVLESPSKPLAPADEDELLPLIPPEPISG---GVPFQSVLVN 1861



 Score = 48.5 bits (114), Expect = 4e-05
 Identities = 110/461 (23%), Positives = 148/461 (32%), Gaps = 74/461 (16%)

Query: 268  PKPAAHLAAPANGSAPSAPAQPPCFHLALPQNSPSPAAGQPVTVAQGAPGSLTHSPPAAG 327
            P P    A P+   AP+ PA  P          PSP  G      +GAP     +PP+  
Sbjct: 1065 PSPKGGPATPSLKGAPTPPAATP----------PSPKGGPATPSPKGAPMPPAATPPSPK 1114

Query: 328  QSHMTLVSSPLPVGQNSLTLQPPAPQPVFLSHGVPLHQSVNPPVLPLSQPVGPVNKSVGT 387
                 L + P      +    PP+P+      G+        P  P + P  P  K    
Sbjct: 1115 GG---LATPPHKGAPTTPAATPPSPK-----GGLATPPPKGAPTTPAATPPSP--KGGLA 1164

Query: 388  SVLPINQTVRPGVLPLTQPVGPINRPVGPGVLPVSPSVTP----GVLQAVSPGVLSVSRA 443
            +  P      P   P   P G +  P  P   P +P+ TP    G L   SP     + A
Sbjct: 1165 TPPPKGAPTTPAATP-PSPKGGLATP-SPKGAPTTPAATPPSPKGGLATPSPKGAPTTPA 1222

Query: 444  VPSGVLPAGQMTPAGQMTPAGVIPGQTATSGVLPTGQMVQSGVLPVGQTAPSRVLPPGQT 503
                    G  TP+ +  P    P  T  S   P G        P  + AP+   PP  T
Sbjct: 1223 ATPPSPKGGLATPSPKGAP--TTPAATPPS---PKG----GPATPPPKGAPT---PPAAT 1270

Query: 504  APLRVISAGQVVPSGLLSPNQTVSSSAVVPVNQGVNSGVLQLSQPVVSGVLPVGQPVRPG 563
             P   +  G   P    +PN  V      P  +G  +       P      P      PG
Sbjct: 1271 PP--SLKGGLATPPHKGAPNPAV---VTPPSPKGGPATSPPKGAPTPPAATPPSPKGSPG 1325

Query: 564  VLQLNQTVGTNILPVNQPVRPGASQNTTFLTSGSILRQLIPTGKQVNGIPTYTLAPVSVT 623
                  T      P    V P + + T  L + +      P+ K   G PT    P S  
Sbjct: 1326 ------TPPPKGAPTPPAVTPPSPKGTPTLPATT------PSSK---GGPT---TPSSKE 1367

Query: 624  LPVPPGGLATVAPPQMPIQLLPSGAAAPMAGSMPGMPSPPVLVNAAQSVFVQASSSAADT 683
             P PP   AT +    P    PS    P   S  G P+ P +        +  S   A  
Sbjct: 1368 GPTPPA--ATPSHKGGPAMTPPSPKRGPAIPSPKGDPTSPAV--------IPLSPKKAPA 1417

Query: 684  NQVLKQAKQWKTCPVCNELFPSNVYQVHMEVAHKHSESKSG 724
              V ++       P   +L P  V  V ++ A   S  K G
Sbjct: 1418 TPVTREG---AATPSKGDLTPPAVTPVSLKKAPATSAPKGG 1455



 Score = 43.9 bits (102), Expect = 9e-04
 Identities = 95/408 (23%), Positives = 149/408 (36%), Gaps = 44/408 (10%)

Query: 276 APANGSAPSAPAQPPCFHLALPQNSPSPAAGQPVTVAQGAPGSLTHSPPAAGQSHMTLVS 335
           A       S P   P   LA+            V ++   PGSL+   P +  + ++L +
Sbjct: 221 ASIQSGVASLPQTTPTTTLAIASPQVKDTTISSVLISPQNPGSLSLKGPVSPPAALSLST 280

Query: 336 SPLPVGQNSLTLQPPAPQPVFL----SHGVPLHQSVNPPVLPLSQPVGPVNKSVGT-SVL 390
             LPV  +S     P   P F     SH  PLHQS    V  L Q  GP   S  T   +
Sbjct: 281 QSLPVVTSSQKTAGPNTPPDFPISLGSHLAPLHQSSFGSVQLLGQ-TGPSALSDPTVKTI 339

Query: 391 PINQTVRPGVLPLTQ---PVGPINRPVGPGVLPVSPSVTPGVLQAVSPGVLSVSRAVPSG 447
            ++ +      P  +   P  P    V P  +   P V P V +   P  +S     PSG
Sbjct: 340 SVDHSSTGASYPSQRSVIPPLPSRNEVVPATVAAFPVVAPSVDK--GPSTISSITCSPSG 397

Query: 448 VLPAGQMTPAGQMTPAGVIPGQTATSGVLPTGQMVQSGVLPVGQTAPSRVLPPGQTAPLR 507
            L    +  +  ++P   +  +++ +       + Q  V  VG T      P   T P  
Sbjct: 398 SL---NVATSFSLSPTTSLILKSSPNATYHYPLVAQMPVSSVGTT------PLVVTNPCT 448

Query: 508 VISAGQVVPSGLLSPNQTVSSSAVVPVNQGVNSGVLQLSQPVVSGVLPVGQPVRPGVLQL 567
           + +A             T +      V+  ++SG +   +P     L V  PV P     
Sbjct: 449 IAAA------------PTTTFEVATCVSPPMSSGPISNIEPTSPAAL-VMAPVAPKE-PS 494

Query: 568 NQTVGTNILPVNQPVRPGASQNTTFLTSGSILRQLIPTGKQVNGIP-TYTLAPVSVTLPV 626
            Q   T  +PV+ P+     ++   L S  +++   PT K +  +P +   AP S   P 
Sbjct: 495 TQVATTLRIPVSPPLPD--PEDLKNLPSSVLVK--FPTQKDLQTVPASLEGAPFS---PA 547

Query: 627 PPGGLATVAPPQMP-IQLLPSGAAA-PMAGSMPGMPSPPVLVNAAQSV 672
             G      P  +P +Q  P  + +     S P +P  P    A +S+
Sbjct: 548 QAGLTTKKDPTVLPLVQAAPKNSPSFQSTSSSPEIPLSPEATLAKKSL 595



 Score = 40.4 bits (93), Expect = 0.010
 Identities = 56/254 (22%), Positives = 87/254 (34%), Gaps = 35/254 (13%)

Query: 268  PKPAAHLAAPANGSAPSAPAQPPCFHLALPQNSPSPAAGQPVTVAQGAPGSLTHSPPAAG 327
            P P    A PA    P++P   P      P +  S       TV Q + G      P A 
Sbjct: 1622 PSPEKGPATPAPKGTPTSPPVTPSSLKDSPTSPASVTCKMGATVPQASKGLPAKKGPTAL 1681

Query: 328  QSHMT--------LVSSPLPVG----QNSLTLQPPAPQPVFLSHGV-PLHQSVNPPVLPL 374
            +  +         ++++P   G    ++S T  P  P P   +    PL      P+LP+
Sbjct: 1682 KEVLVAPAPESTPIITAPTRKGPQTKKSSATSPPICPDPSAKNGSKGPLSTVAPAPLLPV 1741

Query: 375  SQ--------------PVGPVNKSVGTSVLPINQTVRPGVLPLTQPVGPINRPVGPGVLP 420
             +              P GP+      +  P+       VLP  +       P  P  LP
Sbjct: 1742 QKDSSKTAKGKDASHSPKGPLAPPESKASTPLTAAAFEKVLPKPESASVSAAPSPPVSLP 1801

Query: 421  VSPSVTPGV-----LQAVSPGVLSVSRAVPSGVLPAGQMTPAGQMTPAGVIPGQTATSGV 475
            ++PS  P +         SPG++  S + P       ++ P   + P   I G      V
Sbjct: 1802 LAPSPVPTLPPKQQFLPSSPGLVLESPSKPLAPADEDELLP---LIPPEPISGGVPFQSV 1858

Query: 476  LPTGQMVQSGVLPV 489
            L      +S  +PV
Sbjct: 1859 LVNMPTPKSAGIPV 1872



 Score = 39.7 bits (91), Expect = 0.016
 Identities = 92/405 (22%), Positives = 142/405 (35%), Gaps = 79/405 (19%)

Query: 316 PGSLTHSPPAAGQ--------SHMTLVSSPLPV----GQNSLTLQPP---APQPVFLSHG 360
           PG  T + PA  Q        + +  +SS L V    GQ   TL PP   APQ   LS  
Sbjct: 2   PGEATETVPATEQELPQPQAETAVLPMSSALSVTAALGQPGPTLPPPCSPAPQQCPLSAA 61

Query: 361 VPLHQSVNPPVLPLSQPVGPVNKSVGTSVLPINQTVRPGVLPLTQPVGPINRPVGPGVLP 420
                  +P  +  +    P  +S   + LP+                    P  P  LP
Sbjct: 62  NQASPFPSPSTIASTPLEVPFPQSSSGTALPLGTA-----------------PEAPTFLP 104

Query: 421 --VSPSVTPGVLQAVSPGVLSVSRAVPSGVLPAGQMTPA-GQMTPAGVIPGQTATSGVLP 477
             + P ++P  L   SP +    +  PS   P   +  A   +  +   P    TS   P
Sbjct: 105 NLIGPPISPAALALASPMIAPTLKGTPSSSAPLALVALAPHSVQKSSAFPPNLLTSP--P 162

Query: 478 TGQMVQSGVL-----PVGQTAPSRVL----------PPGQTAPLRVISAGQVVPSGLLSP 522
           +  + +SG +     P+  + P   L          P G  +P  ++S    VP   ++P
Sbjct: 163 SVAVAESGSVITLSAPIAPSEPKTNLNKVPSEVVPNPKGTPSPPCIVS---TVPYHCVTP 219

Query: 523 NQTVSSSAVVPVNQGVNSGVLQLSQP-----VVSGVLPVGQPVRPGVLQLNQTV------ 571
             ++  S V  + Q   +  L ++ P      +S VL    P  PG L L   V      
Sbjct: 220 MASI-QSGVASLPQTTPTTTLAIASPQVKDTTISSVLI--SPQNPGSLSLKGPVSPPAAL 276

Query: 572 --GTNILPVNQPVRPGASQNTTFLTSGSILRQLIPTGKQVNGIPTYTLAPVSVTLPVPPG 629
              T  LPV    +  A  NT      S+   L P  +        +   V +     P 
Sbjct: 277 SLSTQSLPVVTSSQKTAGPNTPPDFPISLGSHLAPLHQS-------SFGSVQLLGQTGPS 329

Query: 630 GLATVAPPQMPIQLLPSGAAAPMAGS-MPGMPSPPVLVNAAQSVF 673
            L+      + +    +GA+ P   S +P +PS   +V A  + F
Sbjct: 330 ALSDPTVKTISVDHSSTGASYPSQRSVIPPLPSRNEVVPATVAAF 374



 Score = 38.1 bits (87), Expect = 0.048
 Identities = 77/334 (23%), Positives = 110/334 (32%), Gaps = 81/334 (24%)

Query: 262  KQTHIAPKPAAHLAAPANGSAPSAPAQ----------------PPCFHLALPQNSPSPAA 305
            K+T   P P    A P++  A S PA                 PP      P+ +P+P A
Sbjct: 1559 KKTPAIPTPKEAPATPSSKEASSPPAVTPSTYKGAPSPKELLIPPAVTSPSPKEAPTPPA 1618

Query: 306  GQPVTVAQG----APGSLTHSPPAAGQSHMTLVSSPLPV-------------------GQ 342
              P +  +G    AP     SPP    S     +SP  V                   G 
Sbjct: 1619 VTPPSPEKGPATPAPKGTPTSPPVTPSSLKDSPTSPASVTCKMGATVPQASKGLPAKKGP 1678

Query: 343  NSL--TLQPPAPQ-------PVFLSHGVPLHQSVNPPVLP----LSQPVGPVNKSVGTSV 389
             +L   L  PAP+       P           + +PP+ P     +   GP++      +
Sbjct: 1679 TALKEVLVAPAPESTPIITAPTRKGPQTKKSSATSPPICPDPSAKNGSKGPLSTVAPAPL 1738

Query: 390  LPI---NQTVRPGVLPLTQPVGPINRPVGPGVLPVSPSVTPGVLQAVSPGVLSVSRA--- 443
            LP+   +     G      P GP+  P      P++ +    VL    P   SVS A   
Sbjct: 1739 LPVQKDSSKTAKGKDASHSPKGPLAPPESKASTPLTAAAFEKVLP--KPESASVSAAPSP 1796

Query: 444  ---VPSGVLPAGQMTPAGQMTPAGVIPGQTATSGVLPTGQMVQSGVLPVGQTAPSRVLPP 500
               +P    P   + P  Q  P+   PG    S   P     +  +LP        ++PP
Sbjct: 1797 PVSLPLAPSPVPTLPPKQQFLPSS--PGLVLESPSKPLAPADEDELLP--------LIPP 1846

Query: 501  GQTAPLRVISAGQVVPSGLLSPNQTVSSSAVVPV 534
                    IS G  VP   +  N     SA +PV
Sbjct: 1847 ------EPISGG--VPFQSVLVNMPTPKSAGIPV 1872


>gi|98986457 host cell factor 1 [Homo sapiens]
          Length = 2035

 Score = 61.2 bits (147), Expect = 5e-09
 Identities = 113/487 (23%), Positives = 170/487 (34%), Gaps = 76/487 (15%)

Query: 207 EKIPPPDKYYCKKCNANASSQDALMYHILTSDIHRDLENKLRSVISEHIKRTGLLKQTHI 266
           EK PPP +    + N N  S +     + T+D +                   L  Q + 
Sbjct: 362 EKPPPPARVQLVRANTN--SLEVSWGAVATADSYL------------------LQLQKYD 401

Query: 267 APKPAAHLAAPANGSAPSAPAQPPCFHLALPQNSPSPAAGQPVTVAQGAPGSLTHSPPAA 326
            P  AA   +P     PS PA PP         SP+PAA  P        G +T  P AA
Sbjct: 402 IPATAATATSPTPNPVPSVPANPP--------KSPAPAAAAPAVQPLTQVG-ITLLPQAA 452

Query: 327 GQSHMTLVSSPLPVGQNSLTLQPPAPQPVFLSHGVPLHQSVNPPVLPLSQPVGPVNKSVG 386
                T     LP    S    P A +    + GVP    V  P      P+  +  +  
Sbjct: 453 PAPPTTTTIQVLPTVPGSSISVPTAAR----TQGVPAVLKVTGPQATTGTPLVTMRPASQ 508

Query: 387 TSVLPINQTVRPGVLPLTQP--------VGPINRPVGPGVLPVSPSVTPGVLQAVSPGVL 438
               P+  T  P  + +  P        +G   +  G   L  + + T  +  + +P VL
Sbjct: 509 AGKAPVTVTSLPAGVRMVVPTQSAQGTVIGSSPQMSGMAALAAAAAATQKIPPSSAPTVL 568

Query: 439 SVSRAVPSG--VLPAGQMTPAGQMTPAGVIPGQTATSGVLPTGQMVQSGVLPVG------ 490
           S    VP+G  ++    +TP     PA V    +      P  +M+++    VG      
Sbjct: 569 S----VPAGTTIVKTMAVTPGTTTLPATVKVASSPVMVSNPATRMLKTAAAQVGTSVSSA 624

Query: 491 -QTAPSRVLPPGQTAPLRVISAGQVVPS---GLLSPNQTVSSSAVVP------VNQGVNS 540
             T+   ++   ++  + V    QVV +   G+      V S   VP       N G   
Sbjct: 625 TNTSTRPIITVHKSGTVTVAQQAQVVTTVVGGVTKTITLVKSPISVPGGSALISNLGKVM 684

Query: 541 GVLQLSQPVVSGVLPVGQPVRPGVLQLNQTVGTNILPVNQPVRPGASQNTTFLTSGSILR 600
            V+Q      S V   GQ     V Q+ QT G   LP    ++         +TS     
Sbjct: 685 SVVQTKPVQTSAV--TGQASTGPVTQIIQTKGP--LPAGTILK--------LVTSADGKP 732

Query: 601 QLIPTGKQVNGIPTY-TLAPVSVTLPVPPGGLATVAPPQMPIQLLPSGAAAPMAGSMPGM 659
             I T  Q +G  T  T+  +S   P       T     +P+  + + A A    S PG+
Sbjct: 733 TTIITTTQASGAGTKPTILGISSVSPSTTKPGTTTIIKTIPMSAIITQAGATGVTSSPGI 792

Query: 660 PSPPVLV 666
            SP  ++
Sbjct: 793 KSPITII 799



 Score = 44.7 bits (104), Expect = 5e-04
 Identities = 84/378 (22%), Positives = 137/378 (36%), Gaps = 74/378 (19%)

Query: 309 VTVAQGAPGSLTHSPPAAGQSHMTLVSSPLPVGQNSLTLQP-----PAPQPVFLSHGVPL 363
           VTVAQ A   +  +        +TLV SP+ V   S  +          Q   +      
Sbjct: 641 VTVAQQA--QVVTTVVGGVTKTITLVKSPISVPGGSALISNLGKVMSVVQTKPVQTSAVT 698

Query: 364 HQSVNPPVLPLSQPVGPVNKSVGTSVLPINQTVRPGVLPLTQPVGPINRPVGPGVLPVSP 423
            Q+   PV  + Q  GP+       ++         ++  TQ  G   +P   G+  VSP
Sbjct: 699 GQASTGPVTQIIQTKGPLPAGTILKLVTSADGKPTTIITTTQASGAGTKPTILGISSVSP 758

Query: 424 SVTPGVLQAVSPGVLSVSRAVPSGVLPAGQMTPAGQMTPAGVIPGQTATSGVLPTGQMVQ 483
           S T        PG  ++ + +P   +          +T AG   G T++ G+     ++ 
Sbjct: 759 STT-------KPGTTTIIKTIPMSAI----------ITQAGAT-GVTSSPGIKSPITIIT 800

Query: 484 SGVLPVGQTAPSRVLPP--------GQTAPLRVISAG---------QVVPSGLLSPNQTV 526
           + V+  G  AP++++          GQ    +V+  G         + VP G +     V
Sbjct: 801 TKVMTSGTGAPAKIITAVPKIATGHGQQGVTQVVLKGAPGQPGTILRTVPMGGVRLVTPV 860

Query: 527 SSSAVVPVNQGV----NSGVLQLSQPVVSGVLPV------GQPVRPGVLQLNQTVGTNIL 576
           + SAV P    +     +GV  L    V+G +        G      +     T+GT   
Sbjct: 861 TVSAVKPAVTTLVVKGTTGVTTLG--TVTGTVSTSLAGAGGHSTSASLATPITTLGTIAT 918

Query: 577 PVNQPVRPGA----SQNTTFLTSGSILRQLIPTGKQVNGIPTYTLAPVS----VTLPVPP 628
             +Q + P A    +  TT   +G +              PT T+ PVS    VTL   P
Sbjct: 919 LSSQVINPTAITVSAAQTTLTAAGGLTT------------PTITMQPVSQPTQVTLITAP 966

Query: 629 GGLATVAPPQMPIQLLPS 646
            G+       +P+ +L S
Sbjct: 967 SGVEAQPVHDLPVSILAS 984


>gi|239749951 PREDICTED: similar to mucin 2 [Homo sapiens]
          Length = 2639

 Score = 60.1 bits (144), Expect = 1e-08
 Identities = 83/407 (20%), Positives = 132/407 (32%), Gaps = 25/407 (6%)

Query: 288  QPPCFHLALPQN-SPSPAAGQPVTVAQGAPGSLTHSPPAAGQSHMTLVSSPLPVGQNSLT 346
            QP        +N +P+P            P S   + P    +  T+  +P P G  + T
Sbjct: 1299 QPTTMTTTTTENPTPTPITTTTTVTPTPTPTSTQSTTPTPITTTTTVTPTPTPTGTQTPT 1358

Query: 347  LQP--------PAPQPVFLSHGVPLHQSVNPPVLPLSQPVGPVNKSVGTSVLPINQTVRP 398
              P        P P P           +    V P   P G   ++  ++ +    TV P
Sbjct: 1359 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG--TQTPTSTPITTTTTVTP 1416

Query: 399  GVLPLTQPVGPINRPVGPGVLPVSPSVTPGVLQAVSPGVLSVSRAVPSGVLPAGQMTPAG 458
               P T    P   P+      V+P+ TP   QA +P  ++ +  V     P G  TP  
Sbjct: 1417 TPTP-TGTQTPTTTPI-TTTTTVTPTPTPTGTQAPTPTAITTTSTVTPTPTPTGTQTPTT 1474

Query: 459  Q--MTPAGVIPGQTATSGVLPTGQMVQSGVLPVGQTAPSRVLPPGQTAPLRVISAGQV-V 515
                T   V P  T T    PT   + +         P+    P  T      +      
Sbjct: 1475 TPITTTTTVTPTPTPTGTQTPTPTAITTTTTVTPTPTPTGTQTPTSTPITTTTTVTPTPT 1534

Query: 516  PSGLLSPNQT-VSSSAVVPVNQGVNSGVLQLSQPVVSGVLPVGQPVRPGV---LQLNQTV 571
            P+G  +P  T +S++  V             + P+ +       P   G      +  T 
Sbjct: 1535 PTGTQTPTPTPISTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTVLITT 1594

Query: 572  GTNILPVNQPVRPGASQNTTFLTSGSILRQLIPTGKQVNGIPTYTLAPVSVTLPVPPGGL 631
             T + P   P    ++  T   T+ ++     PTG Q     T T+ P+S T  V P   
Sbjct: 1595 TTTMTPTPTPTSTKSTTVTPITTTTTVTATPTPTGTQ-----TPTMIPISTTTTVTPTPT 1649

Query: 632  ATVAPPQMPIQLLPSGAAAPMAGSMPGMPSPPVLVNAAQSVFVQASS 678
             T      P     +  A     + P   S P    +  S   ++++
Sbjct: 1650 PTTGSTGPPTHTSTAPIAELTTSNPPPESSTPQTSRSTSSPLTESTT 1696



 Score = 56.6 bits (135), Expect = 1e-07
 Identities = 91/443 (20%), Positives = 136/443 (30%), Gaps = 62/443 (13%)

Query: 258  TGLLKQTHIAPKPAAHLAAPANGSAPSAPAQPPCFHLALPQNSPSPAAGQ-PVTVAQGAP 316
            T +   T + P P          +    P   P         +P+P   Q P T      
Sbjct: 1337 TPITTTTTVTPTPTP--------TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 1388

Query: 317  GSLTHSPPAAGQ---------SHMTLVSSPLPVGQNSLTLQP--------PAPQPVFLSH 359
             ++T +P   G          +  T+  +P P G  + T  P        P P P     
Sbjct: 1389 TTVTPTPTPTGTQTPTSTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQA 1448

Query: 360  GVPLHQSVNPPVLPLSQPVG-------PVNKSVGTSVLPI---NQTVRPGVLPLTQPVGP 409
              P   +    V P   P G       P+  +   +  P     QT  P  +  T  V P
Sbjct: 1449 PTPTAITTTSTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTPTAITTTTTVTP 1508

Query: 410  INRPVG---PGVLP------VSPSVTPGVLQAVSPGVLSVSRAVPSGVLPAGQMTPAGQM 460
               P G   P   P      V+P+ TP   Q  +P  +S +  V     P G  TP    
Sbjct: 1509 TPTPTGTQTPTSTPITTTTTVTPTPTPTGTQTPTPTPISTTTTVTPTPTPTGTQTP---- 1564

Query: 461  TPAGVIPGQTATSGVLPTGQMVQSGVLPVGQTAPSRVLPPGQTAPLRVISAGQVVPSGLL 520
            T   +    T T    PTG    + VL    T  +    P  T    V            
Sbjct: 1565 TTTPITTTTTVTPTPTPTGTQTPTTVLITTTTTMTPTPTPTSTKSTTVTPITTTTTVTAT 1624

Query: 521  SPNQTVSSSAVVPVNQGVNSGVLQLSQPVVSGVLPVGQPVRPGVLQLNQTVGTNILPVNQ 580
                   +  ++P++    + V     P        G P       + +   +N  P + 
Sbjct: 1625 PTPTGTQTPTMIPIS--TTTTVTPTPTPTTGST---GPPTHTSTAPIAELTTSNPPPESS 1679

Query: 581  PVRPGASQNTTFLTSGSILRQLIPTGKQVNGIPTYTLAPVSVTLPVPPGGLATVAPPQMP 640
              +   S ++    S ++L  L P  +      T T  P + T P    G  T++PP   
Sbjct: 1680 TPQTSRSTSSPLTESTTLLSTLPPAIEM-----TSTAPPSTPTAPTTTSGGHTLSPPP-- 1732

Query: 641  IQLLPSGAAAPMAGSMPGMPSPP 663
                 S    P  G+  G  S P
Sbjct: 1733 -STTTSPPGTPTRGTTTGSSSAP 1754



 Score = 35.0 bits (79), Expect = 0.40
 Identities = 48/197 (24%), Positives = 67/197 (34%), Gaps = 22/197 (11%)

Query: 300  SPSPAAGQ-PVTVAQGAPGSLTHSP-PAAGQSHM--------TLVSSPLPVGQNSLTLQP 349
            +P+P   Q P TV      ++T +P P + +S          T+ ++P P G  + T+ P
Sbjct: 1578 TPTPTGTQTPTTVLITTTTTMTPTPTPTSTKSTTVTPITTTTTVTATPTPTGTQTPTMIP 1637

Query: 350  --------PAPQPVFLSHGVPLHQSVNPPVLPLSQPVGPVNKSVGTSVLPINQTVRPGVL 401
                    P P P   S G P H S  P     +    P + +  TS    +       L
Sbjct: 1638 ISTTTTVTPTPTPTTGSTGPPTHTSTAPIAELTTSNPPPESSTPQTSRSTSSPLTESTTL 1697

Query: 402  PLTQPVGPINRPVGPGVLPVSPSVTPGVLQAVSPGVLSVSRAVPSGVLPAGQMTPAGQMT 461
              T P         P   P +P+ T G      P   + S   P G  P    T      
Sbjct: 1698 LSTLPPAIEMTSTAPPSTPTAPTTTSGGHTLSPPPSTTTS---PPGT-PTRGTTTGSSSA 1753

Query: 462  PAGVIPGQTATSGVLPT 478
            P       T TS   PT
Sbjct: 1754 PTPSTVQTTTTSAWTPT 1770


>gi|46397392 pogo transposable element with ZNF domain isoform 3
           [Homo sapiens]
          Length = 363

 Score = 59.7 bits (143), Expect = 2e-08
 Identities = 62/206 (30%), Positives = 85/206 (41%), Gaps = 16/206 (7%)

Query: 305 AGQPVTVAQGAPGSLTHSP-PAAGQSHMTLVSSPLPVGQNS--LTLQPPAPQPVFLS-HG 360
           AG P+    G P  LT +P P  G      V  P+ V QN+  +T  P A QP+F++  G
Sbjct: 95  AGNPLVQQGGQPLILTQNPAPGLGTMVTQPVLRPVQVMQNANHVTSSPVASQPIFITTQG 154

Query: 361 VPLHQSVNPPVLPLSQPVGPVNKSVGTSVLPINQTVRPGVLPLTQPVGPIN-----RPVG 415
            P+ ++V P    ++Q    +N   G +V PI     PG   +   VG         PV 
Sbjct: 155 FPV-RNVRPVQNAMNQVGIVLNVQQGQTVRPITLVPAPGTQFVKPTVGVPQVFSQMTPVR 213

Query: 416 PG-VLPVSPSVTPGVLQAVSPGVLSVSRAVPSGVLPAGQMTPAGQMTPAGVIPGQTATSG 474
           PG  +PV P  T      V P  L++   VP       + TP+   TP    P       
Sbjct: 214 PGSTMPVRP--TTNTFTTVIPATLTIRSTVPQSQSQQTKSTPSTSTTPTATQPTSLGQLA 271

Query: 475 VLPTGQMVQSGVLPVGQTAPSRVLPP 500
           V   GQ  Q+      + APS   PP
Sbjct: 272 VQSPGQSNQT---TNPKLAPSFPSPP 294



 Score = 46.2 bits (108), Expect = 2e-04
 Identities = 70/294 (23%), Positives = 108/294 (36%), Gaps = 29/294 (9%)

Query: 420 PVSPSVTPGVLQAVSPGVLSVSRAVPSGVLPAGQMTPAGQMTPAGVIPGQTATSGVLPTG 479
           PVS  V P    A   G LS S  V S      Q + + + T   +I    A + ++  G
Sbjct: 48  PVSAPV-PIAAHASVAGHLSTSTTVSSS---GAQNSDSTKKTLVTLIANNNAGNPLVQQG 103

Query: 480 Q----MVQSGVLPVGQTAPSRVLPPGQTAP-LRVISAGQVVPSGLLSPNQTVSSSAVVPV 534
                + Q+    +G      VL P Q       +++  V    +    Q      V PV
Sbjct: 104 GQPLILTQNPAPGLGTMVTQPVLRPVQVMQNANHVTSSPVASQPIFITTQGFPVRNVRPV 163

Query: 535 NQGVNSGVLQLSQPVVSGVLPVGQPVRPGVLQLNQTVG-----TNILPVN----QPVRPG 585
              +N   + L+      V P+     PG   +  TVG     + + PV      PVRP 
Sbjct: 164 QNAMNQVGIVLNVQQGQTVRPITLVPAPGTQFVKPTVGVPQVFSQMTPVRPGSTMPVRPT 223

Query: 586 ASQNTTFLTSGSILRQLIPTGK--QVNGIPTYTLAPVSVTLPVPPGGLATVAPPQMPIQL 643
            +  TT + +   +R  +P  +  Q    P+ +  P + T P   G LA  +P Q     
Sbjct: 224 TNTFTTVIPATLTIRSTVPQSQSQQTKSTPSTSTTPTA-TQPTSLGQLAVQSPGQSNQTT 282

Query: 644 LPSGAAAPMAGSMPGMPSPPVLVNAAQSVFVQASSSAADTNQVLKQAKQWKTCP 697
            P  A        P  PSPP +  A+     +   +  ++N+V K      T P
Sbjct: 283 NPKLA--------PSFPSPPAVSIASFVTVKRPGVTGENSNEVAKLVNTLNTIP 328


>gi|46397390 pogo transposable element with ZNF domain isoform 1
           [Homo sapiens]
          Length = 1410

 Score = 59.7 bits (143), Expect = 2e-08
 Identities = 62/206 (30%), Positives = 85/206 (41%), Gaps = 16/206 (7%)

Query: 305 AGQPVTVAQGAPGSLTHSP-PAAGQSHMTLVSSPLPVGQNS--LTLQPPAPQPVFLS-HG 360
           AG P+    G P  LT +P P  G      V  P+ V QN+  +T  P A QP+F++  G
Sbjct: 95  AGNPLVQQGGQPLILTQNPAPGLGTMVTQPVLRPVQVMQNANHVTSSPVASQPIFITTQG 154

Query: 361 VPLHQSVNPPVLPLSQPVGPVNKSVGTSVLPINQTVRPGVLPLTQPVGPIN-----RPVG 415
            P+ ++V P    ++Q    +N   G +V PI     PG   +   VG         PV 
Sbjct: 155 FPV-RNVRPVQNAMNQVGIVLNVQQGQTVRPITLVPAPGTQFVKPTVGVPQVFSQMTPVR 213

Query: 416 PG-VLPVSPSVTPGVLQAVSPGVLSVSRAVPSGVLPAGQMTPAGQMTPAGVIPGQTATSG 474
           PG  +PV P  T      V P  L++   VP       + TP+   TP    P       
Sbjct: 214 PGSTMPVRP--TTNTFTTVIPATLTIRSTVPQSQSQQTKSTPSTSTTPTATQPTSLGQLA 271

Query: 475 VLPTGQMVQSGVLPVGQTAPSRVLPP 500
           V   GQ  Q+      + APS   PP
Sbjct: 272 VQSPGQSNQT---TNPKLAPSFPSPP 294



 Score = 46.2 bits (108), Expect = 2e-04
 Identities = 70/294 (23%), Positives = 108/294 (36%), Gaps = 29/294 (9%)

Query: 420 PVSPSVTPGVLQAVSPGVLSVSRAVPSGVLPAGQMTPAGQMTPAGVIPGQTATSGVLPTG 479
           PVS  V P    A   G LS S  V S      Q + + + T   +I    A + ++  G
Sbjct: 48  PVSAPV-PIAAHASVAGHLSTSTTVSSS---GAQNSDSTKKTLVTLIANNNAGNPLVQQG 103

Query: 480 Q----MVQSGVLPVGQTAPSRVLPPGQTAP-LRVISAGQVVPSGLLSPNQTVSSSAVVPV 534
                + Q+    +G      VL P Q       +++  V    +    Q      V PV
Sbjct: 104 GQPLILTQNPAPGLGTMVTQPVLRPVQVMQNANHVTSSPVASQPIFITTQGFPVRNVRPV 163

Query: 535 NQGVNSGVLQLSQPVVSGVLPVGQPVRPGVLQLNQTVG-----TNILPVN----QPVRPG 585
              +N   + L+      V P+     PG   +  TVG     + + PV      PVRP 
Sbjct: 164 QNAMNQVGIVLNVQQGQTVRPITLVPAPGTQFVKPTVGVPQVFSQMTPVRPGSTMPVRPT 223

Query: 586 ASQNTTFLTSGSILRQLIPTGK--QVNGIPTYTLAPVSVTLPVPPGGLATVAPPQMPIQL 643
            +  TT + +   +R  +P  +  Q    P+ +  P + T P   G LA  +P Q     
Sbjct: 224 TNTFTTVIPATLTIRSTVPQSQSQQTKSTPSTSTTPTA-TQPTSLGQLAVQSPGQSNQTT 282

Query: 644 LPSGAAAPMAGSMPGMPSPPVLVNAAQSVFVQASSSAADTNQVLKQAKQWKTCP 697
            P  A        P  PSPP +  A+     +   +  ++N+V K      T P
Sbjct: 283 NPKLA--------PSFPSPPAVSIASFVTVKRPGVTGENSNEVAKLVNTLNTIP 328


>gi|46397394 pogo transposable element with ZNF domain isoform 2
           [Homo sapiens]
          Length = 1357

 Score = 59.7 bits (143), Expect = 2e-08
 Identities = 62/206 (30%), Positives = 85/206 (41%), Gaps = 16/206 (7%)

Query: 305 AGQPVTVAQGAPGSLTHSP-PAAGQSHMTLVSSPLPVGQNS--LTLQPPAPQPVFLS-HG 360
           AG P+    G P  LT +P P  G      V  P+ V QN+  +T  P A QP+F++  G
Sbjct: 42  AGNPLVQQGGQPLILTQNPAPGLGTMVTQPVLRPVQVMQNANHVTSSPVASQPIFITTQG 101

Query: 361 VPLHQSVNPPVLPLSQPVGPVNKSVGTSVLPINQTVRPGVLPLTQPVGPIN-----RPVG 415
            P+ ++V P    ++Q    +N   G +V PI     PG   +   VG         PV 
Sbjct: 102 FPV-RNVRPVQNAMNQVGIVLNVQQGQTVRPITLVPAPGTQFVKPTVGVPQVFSQMTPVR 160

Query: 416 PG-VLPVSPSVTPGVLQAVSPGVLSVSRAVPSGVLPAGQMTPAGQMTPAGVIPGQTATSG 474
           PG  +PV P  T      V P  L++   VP       + TP+   TP    P       
Sbjct: 161 PGSTMPVRP--TTNTFTTVIPATLTIRSTVPQSQSQQTKSTPSTSTTPTATQPTSLGQLA 218

Query: 475 VLPTGQMVQSGVLPVGQTAPSRVLPP 500
           V   GQ  Q+      + APS   PP
Sbjct: 219 VQSPGQSNQT---TNPKLAPSFPSPP 241



 Score = 42.7 bits (99), Expect = 0.002
 Identities = 45/178 (25%), Positives = 69/178 (38%), Gaps = 20/178 (11%)

Query: 531 VVPVNQGVNSGVLQLSQPVVSGVLPVGQPVRPGVLQLNQTVG-----TNILPVN----QP 581
           V PV   +N   + L+      V P+     PG   +  TVG     + + PV      P
Sbjct: 107 VRPVQNAMNQVGIVLNVQQGQTVRPITLVPAPGTQFVKPTVGVPQVFSQMTPVRPGSTMP 166

Query: 582 VRPGASQNTTFLTSGSILRQLIPTGK--QVNGIPTYTLAPVSVTLPVPPGGLATVAPPQM 639
           VRP  +  TT + +   +R  +P  +  Q    P+ +  P + T P   G LA  +P Q 
Sbjct: 167 VRPTTNTFTTVIPATLTIRSTVPQSQSQQTKSTPSTSTTPTA-TQPTSLGQLAVQSPGQS 225

Query: 640 PIQLLPSGAAAPMAGSMPGMPSPPVLVNAAQSVFVQASSSAADTNQVLKQAKQWKTCP 697
                P  A        P  PSPP +  A+     +   +  ++N+V K      T P
Sbjct: 226 NQTTNPKLA--------PSFPSPPAVSIASFVTVKRPGVTGENSNEVAKLVNTLNTIP 275


>gi|19924099 synapsin I isoform Ia [Homo sapiens]
          Length = 705

 Score = 59.7 bits (143), Expect = 2e-08
 Identities = 88/325 (27%), Positives = 122/325 (37%), Gaps = 80/325 (24%)

Query: 240 HRDLENKL--RSVISEHIKRTGLLKQTHIAPKPAAHLAAPANGSAP------SAPAQPPC 291
           H+D + +L    V+++  +     +Q   +P   +H   P+ G+ P        PA PP 
Sbjct: 398 HQDEDKQLIVELVVNKMAQALPRQRQRDASPGRGSHGQTPSPGALPLGRQTSQQPAGPPA 457

Query: 292 FHLALPQNSPSPAAGQPVTVAQGAPGSLTHSPPAAGQSHMTLVSSPLPVGQNSLT-LQPP 350
                 Q  P P  G P    Q  PG     PP        L   P P GQ  L+ L PP
Sbjct: 458 ------QQRPPPQGGPP----QPGPGPQRQGPP--------LQQRPPPQGQQHLSGLGPP 499

Query: 351 APQPVFLSHGVPLHQSVNPPVLPLSQPVGPVNKSVGTSVLPINQTVRPGVLPLTQPVGPI 410
           A        G PL Q +  P    S P  P +++                 P TQ  G  
Sbjct: 500 A--------GSPLPQRLPSPT---SAPQQPASQAA----------------PPTQGQGRQ 532

Query: 411 NRPV--GPGVLPVS-PSVTPGVLQAVSPGVL----SVSRAVP---SGVLPAGQMT----- 455
           +RPV  GPG  P + P  +P   +   P       SVS   P   SG  P GQ       
Sbjct: 533 SRPVAGGPGAPPAARPPASPSPQRQAGPPQATRQTSVSGPAPPKASGAPPGGQQRQGPPQ 592

Query: 456 ----PAG---QMTPAGVIPGQTATSGVLPTGQMVQSGVLPVGQTAPSRVLPPGQTAPLRV 508
               PAG   Q + AG +P     +G   T Q   SG  P G+  P     P Q  P   
Sbjct: 593 KPPGPAGPTRQASQAGPVP----RTGPPTTQQPRPSGPGPAGRPKPQLAQKPSQDVPPPA 648

Query: 509 ISAGQVVPSGLLSPNQTVSSSAVVP 533
            +A    P   L+ +Q+++++  +P
Sbjct: 649 TAAAGGPPHPQLNKSQSLTNAFNLP 673


>gi|46852161 methyl-CpG binding domain protein 6 [Homo sapiens]
          Length = 1003

 Score = 59.3 bits (142), Expect = 2e-08
 Identities = 105/406 (25%), Positives = 147/406 (36%), Gaps = 63/406 (15%)

Query: 281 SAPSAPAQPPCFHLALP--QNSPSPAAGQPVTVAQGAPGSLTHSPPAAGQSHMTLVSSPL 338
           S+P   A P  FH   P   ++  P    P T   G PGSL   PP+  Q+  TL     
Sbjct: 124 SSPGEGASPQMFHTVSPGPPSARPPCRVPPTTPLNGGPGSLPPEPPSVSQAFPTLAG--- 180

Query: 339 PVGQNSLTLQPPAP-----QPVFLSHG-VPLHQSVNPPVLPLSQPVGPVNKSVGTSVLPI 392
           P G     L  P P      P FL  G  P      PP + L+ P      ++ +S++P 
Sbjct: 181 PGGLFPPRLADPVPSGGSSSPRFLPRGNAPSPAPPPPPAISLNAPSYNWGAALRSSLVPS 240

Query: 393 NQTVRP-----GVLPLTQPVGPINRPVGPGVLPVSPSVTPGVLQAVSPGVLSVSRAVPSG 447
           +    P        P   P+   +  + P  LP S ++      A  P V S +  +P  
Sbjct: 241 DLGSPPAPHASSSPPSDPPLFHCSDALTPPPLPPSNNLPAHPGPASQPPVSSATMHLPLV 300

Query: 448 VLPAGQMTPAGQMTPAGVIPGQTATSGVLPTGQMVQSGVLPVGQTAPSRVLPPGQTAPLR 507
           + P G     G  T  G        S +L      Q   LP   T   R   P   AP  
Sbjct: 301 LGPLG-----GAPTVEGPGAPPFLASSLLSAAAKAQHPPLPPPSTLQGR--RPRAQAP-- 351

Query: 508 VISAGQVVPSGLLSPNQ--TVSSSAVVPVNQGVNSGVLQLSQPVVSGVLPVGQPVRPGVL 565
             SA     S  L P+Q        V  + +G      + S+P      PV QP      
Sbjct: 352 --SASH---SSSLRPSQRRPRRPPTVFRLLEGRGPQTPRRSRP--RAPAPVPQPF----- 399

Query: 566 QLNQTVGTNILPVNQPVRPGASQNTTFLTSGSILRQL-IPTGKQVNGIPTYTLAPVSVTL 624
                   ++   +QP+ P            S+L  L +PT    +   ++ L      L
Sbjct: 400 --------SLPEPSQPILP------------SVLSLLGLPTPGPSHSDGSFNLLGSDAHL 439

Query: 625 PVPPGGLATVAPPQ--MPIQLLPSGAAAPMAGSMPGMPSPPVLVNA 668
           P PP  L++ +PPQ   PIQ    G  +    S+PG P+PP    A
Sbjct: 440 P-PPPTLSSGSPPQPRHPIQPSLPGTTSGSLSSVPGAPAPPAASKA 484



 Score = 45.8 bits (107), Expect = 2e-04
 Identities = 102/431 (23%), Positives = 154/431 (35%), Gaps = 81/431 (18%)

Query: 268 PKPAAHLAAPANGSAPSAPAQPPCFHL-ALPQNSPSPAAGQ------------PVTVAQG 314
           P+  A +  P +   PS P  P    L  LP   PS + G             P T++ G
Sbjct: 389 PRAPAPVPQPFSLPEPSQPILPSVLSLLGLPTPGPSHSDGSFNLLGSDAHLPPPPTLSSG 448

Query: 315 APGSLTH--SPPAAGQSHMTLVSSPLPVGQNSLTLQPPAPQPVFLSHGVPLHQSVNP--P 370
           +P    H   P   G +  +L S P      + +  P  P PV  S    L     P  P
Sbjct: 449 SPPQPRHPIQPSLPGTTSGSLSSVPGAPAPPAASKAPVVPSPVLQSPSEGLGMGAGPACP 508

Query: 371 VLPLSQPVGPVNKSVGTSVLPINQTVRPGVLPLTQPVGPINRPVGPGVLPVSPSVTPGVL 430
           + PL+        S     L ++    PG+L      G +  P+  G  P SP +   + 
Sbjct: 509 LPPLAGGEAFPFPSPEQG-LALSGAGFPGML------GALPLPLSLGQPPPSPLLNHSLF 561

Query: 431 QAVSPGVLSVSRAVPSGVLPAGQMTPAGQMTPAGVIPGQTATSGVLPTGQMVQSGVLPVG 490
             ++ G               GQ  P   + P G  PG     G      ++ + +LP  
Sbjct: 562 GVLTGG--------------GGQPPPEPLLPPPGG-PGPPLAPGEPEGPSLLVASLLP-- 604

Query: 491 QTAPSRVLPPGQTAPLRVISAGQVVPSGLLSPNQTVSSSAVVPVNQGVNSGVLQLSQPVV 550
              PS +LPP    P  ++++   +P  LL+   T           G  SG        +
Sbjct: 605 -PPPSDLLPPPSAPPSNLLAS--FLP--LLALGPTAGDGEGSAEGAGGPSGEPFSGLGDL 659

Query: 551 SGVL--PVGQPVRPGVLQLNQTV---------GTN----ILPVNQPVRPGASQNTTFLTS 595
           S +L  P+  P  P ++ LN  +         GT     +L   QP  P +S  T     
Sbjct: 660 SPLLFPPLSAP--PTLIALNSALLAATLDPPSGTPPQPCVLSAPQPGPPTSSVTTATTDP 717

Query: 596 GSILRQLIPTGKQVNGIPTYTLAPVS--------VTLPVPPGGLATVAPP-------QMP 640
           G+      P+    +G P   L+P+          +L   PG L ++  P       Q+ 
Sbjct: 718 GASSLGKAPSN---SGRPPQLLSPLLGASLLGDLSSLTSSPGALPSLLQPPGPLLSGQLG 774

Query: 641 IQLLPSGAAAP 651
           +QLLP G A P
Sbjct: 775 LQLLPGGGAPP 785



 Score = 32.0 bits (71), Expect = 3.4
 Identities = 84/339 (24%), Positives = 124/339 (36%), Gaps = 71/339 (20%)

Query: 268 PKPAAHLAAPANGSAPSAPAQPPCFHLALPQNSPSP--AAGQP------VTVAQGAPGSL 319
           P P+  L     G       QPP   L  P   P P  A G+P      V      P S 
Sbjct: 550 PPPSPLLNHSLFGVLTGGGGQPPPEPLLPPPGGPGPPLAPGEPEGPSLLVASLLPPPPSD 609

Query: 320 THSPPAAGQSHMTLVSSPLPVGQNSLTLQPPAPQPVFLSHGV--PLHQSVN-----PPVL 372
              PP+A  S+  L++S LP+    L L P A      + G   P  +  +      P+L
Sbjct: 610 LLPPPSAPPSN--LLASFLPL----LALGPTAGDGEGSAEGAGGPSGEPFSGLGDLSPLL 663

Query: 373 --PLSQPVGPVNKSVGTSVL------PINQTVRPGVLPLTQPVGPINRPVGPGVLPVSPS 424
             PLS P  P   ++ +++L      P     +P VL   QP        GP    V+ +
Sbjct: 664 FPPLSAP--PTLIALNSALLAATLDPPSGTPPQPCVLSAPQP--------GPPTSSVTTA 713

Query: 425 VTPGVLQAVSPGVLSVSRAVPSGVLPAGQMTPAGQMTPAGVIPGQTATSGVLPTGQMVQS 484
            T        PG  S+ +A  +   P   ++P    +  G +   T++ G L        
Sbjct: 714 TT-------DPGASSLGKAPSNSGRPPQLLSPLLGASLLGDLSSLTSSPGAL-------- 758

Query: 485 GVLPVGQTAPSRVLPPGQTAPLRVISAG-QVVPSGLLSPNQTVSSSAVVPVNQGVNSGVL 543
                    PS + PPG   PL     G Q++P G   P  + +SS +  + Q +     
Sbjct: 759 ---------PSLLQPPG---PLLSGQLGLQLLPGGGAPPPLSEASSPLACLLQSLQIPPE 806

Query: 544 QLSQPVVSGVLPVG----QPVRPGVLQLNQTVGTNILPV 578
           Q   P +    P      +P RP +  L    G+   PV
Sbjct: 807 QPEAPCLPPESPASALEPEPARPPLSALAPPHGSPDPPV 845


>gi|116284392 mucin 2 precursor [Homo sapiens]
          Length = 5179

 Score = 58.9 bits (141), Expect = 3e-08
 Identities = 85/397 (21%), Positives = 126/397 (31%), Gaps = 31/397 (7%)

Query: 284  SAPAQPPCFHLALPQNS-PSPAAGQPVTVAQGAPGSLTHSPPAAGQSHMTLVSSPLPVGQ 342
            + P+ PP     LP  + PSP    P T     P + T SPP    +     ++P P   
Sbjct: 1404 TTPSPPPTSTTTLPPTTTPSP----PTTTTTTPPPTTTPSPPITTTTTPPPTTTPSPPIS 1459

Query: 343  NSLTLQPPA--------PQPVFLSHGVPLHQSVNPPVLPLSQP--VGPVNKSVGTSVLPI 392
             + T  P          P P   +   P   +  PP      P    P+     T+ LP 
Sbjct: 1460 TTTTPPPTTTPSPPTTTPSPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPASTTTLPP 1519

Query: 393  NQTVRPGVLPLTQPVGPINRPVGPGVLPVSPSVTPGVLQAVSPGVLSVSRAVPSGVLPAG 452
              T  P     T P  P   P  P   P++P  +   L    P   + S    +   P  
Sbjct: 1520 TTTPSPPTTTTTTP-PPTTTPSPPTTTPITPPTSTTTL----PPTTTPSPPPTTTTTPPP 1574

Query: 453  QMTPAGQMTPAGVIPGQTATSGVLPTGQMVQSGVLPVGQTAPSRVLP-PGQTAPLRVISA 511
              TP+   T     P  T T+   P      S       T P    P P  T P+   ++
Sbjct: 1575 TTTPSPPTTTTPSPPTITTTT---PPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTS 1631

Query: 512  GQVVPSGLLSPNQTVSSSAVVPVNQGVNSGVLQLSQPVVSGVLPVGQPVRPGVLQLNQTV 571
               +P          +++   P            S P+ +   P         +    + 
Sbjct: 1632 TTTLPPTTTPSPPPTTTTTPPPTTTPSPPTTTTPSPPITTTTTPPPTTTPSSPITTTPSP 1691

Query: 572  GTNILPVNQPVRPGASQNTTFLTSGSILRQLIPTGKQVNGIPTYTLAPVSVTL-PVPPGG 630
             T  +    P    +S  TT  T  S      P        PT T +P + T+  +PP  
Sbjct: 1692 PTTTMTTPSPTTTPSSPITTTTTPSSTTTPSPPPTTMTTPSPTTTPSPPTTTMTTLPP-- 1749

Query: 631  LATVAPPQMPIQLLPS---GAAAPMAGSMPGMPSPPV 664
              T + P     L PS      +P + + P  P  P+
Sbjct: 1750 -TTTSSPLTTTPLPPSITPPTFSPFSTTTPTTPCVPL 1785



 Score = 55.1 bits (131), Expect = 4e-07
 Identities = 83/398 (20%), Positives = 124/398 (31%), Gaps = 39/398 (9%)

Query: 264  THIAPKPAAHLAAPANGSAPSAPAQPPCFHLALPQNSPSPAAGQPVTVAQGAPGSLTHSP 323
            T   P P    + P   +    P   P      P   P+     P T     P + T +P
Sbjct: 1592 TTTTPPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTPSPPPTTTTTP 1651

Query: 324  PAAGQSHMTLVSSPLPVGQNSLTLQPPAPQPVFLSHGVPLHQSVNPPVLPLSQPVGPVNK 383
            P          ++P P    + T  PP   P       P+  + +PP   ++ P      
Sbjct: 1652 PPTTTPSPPTTTTPSP-PITTTTTPPPTTTP-----SSPITTTPSPPTTTMTTP-----S 1700

Query: 384  SVGTSVLPINQTVRPGVLPLTQPVGPINRPVGPGVLPVSPSVTPGVLQAVSPGVLSVSRA 443
               T   PI  T  P       P         P   P  P+ T   L   +      +  
Sbjct: 1701 PTTTPSSPITTTTTPSSTTTPSPPPTTMTTPSPTTTPSPPTTTMTTLPPTTTSSPLTTTP 1760

Query: 444  VPSGVLPAGQMTPAGQMTPAGVIPGQTATSGVLPTGQMVQSGVLPVGQT-APSRVLPPGQ 502
            +P  + P    +P    TP          +G L +G+   +   P G T     V  PG 
Sbjct: 1761 LPPSITPP-TFSPFSTTTPTTPCVPLCNWTGWLDSGK--PNFHKPGGDTELIGDVCGPGW 1817

Query: 503  TAPLRV-------ISAGQV-------VPSGLLSPNQTVSSSAVVP----VNQGVNSGVLQ 544
             A +         +  GQ+       V  GL+  N+      V+P    +N  +N    +
Sbjct: 1818 AANISCRATMYPDVPIGQLGQTVVCDVSVGLICKNEDQKPGGVIPMAFCLNYEINVQCCE 1877

Query: 545  -LSQPVVSGVLPVGQPVRPGVLQLNQTVGTNILPVNQPVRPGASQNTTFLTSGSILRQLI 603
             ++QP          P  P    +  T  T + P   P        T   T+ ++     
Sbjct: 1878 CVTQPTTMTTTTTENPTPPTTTPITTT--TTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 1935

Query: 604  PTGKQVNGIPTYTLAPVSVTLPVPPGGLATVAPPQMPI 641
            PTG Q    PT T    + T+   P    T  P   PI
Sbjct: 1936 PTGTQT---PTTTPITTTTTVTPTPTPTGTQTPTTTPI 1970



 Score = 51.6 bits (122), Expect = 4e-06
 Identities = 80/385 (20%), Positives = 122/385 (31%), Gaps = 34/385 (8%)

Query: 283  PSAPAQPPCFHLALPQNSPSPAAGQ-PVTVAQGAPGSLTHSPPAAGQ---------SHMT 332
            P+ P   P         +P+P   Q P T       ++T +P   G          +  T
Sbjct: 1893 PTPPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 1952

Query: 333  LVSSPLPVGQNSLTLQP--------PAPQPVFLSHGVPLHQSVNPPVLPLSQPVGPVNKS 384
            +  +P P G  + T  P        P P P           +    V P   P G   ++
Sbjct: 1953 VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG--TQT 2010

Query: 385  VGTSVLPINQTVRPGVLPLTQPVGPINRPVGPGVLPVSPSVTPGVLQAVSPGVLSVSRAV 444
              T+ +    TV P   P T    P   P+      V+P+ TP   Q  +   ++ +  V
Sbjct: 2011 PTTTPITTTTTVTPTPTP-TGTQTPTTTPITT-TTTVTPTPTPTGTQTPTTTPITTTTTV 2068

Query: 445  PSGVLPAGQMTPAGQ--MTPAGVIPGQTATSGVLPTGQMVQSGVLPVGQTAPSRVLPPGQ 502
                 P G  TP      T   V P  T T    PT   + +         P+    P  
Sbjct: 2069 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP-T 2127

Query: 503  TAPLRVISA--GQVVPSGLLSPNQT-VSSSAVVPVNQGVNSGVLQLSQPVVSGVLPVGQP 559
            T P+   +       P+G  +P  T ++++  V             + P+ +       P
Sbjct: 2128 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 2187

Query: 560  VRPGVLQLNQT---VGTNILPVNQPVRPGASQNTTFLTSGSILRQLIPTGKQVNGIPTYT 616
               G      T     T + P   P        T   T+ ++     PTG Q    PT T
Sbjct: 2188 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT---PTTT 2244

Query: 617  LAPVSVTLPVPPGGLATVAPPQMPI 641
                + T+   P    T  P   PI
Sbjct: 2245 PITTTTTVTPTPTPTGTQTPTTTPI 2269



 Score = 51.2 bits (121), Expect = 5e-06
 Identities = 87/431 (20%), Positives = 134/431 (31%), Gaps = 43/431 (9%)

Query: 258  TGLLKQTHIAPKPAAHLAAPANGSAPSAPAQPPCFHLALPQNSPSPAAGQ-PVTVAQGAP 316
            T +   T + P P          +    P   P         +P+P   Q P T      
Sbjct: 3785 TPITTTTTVTPTPTP--------TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 3836

Query: 317  GSLTHSPPAAGQ---------SHMTLVSSPLPVGQNSLTLQP--------PAPQPVFLSH 359
             ++T +P   G          +  T+  +P P G  + T  P        P P P     
Sbjct: 3837 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 3896

Query: 360  GVPLHQSVNPPVLPLSQPVGPVNKSVGTSVLPINQTVRPGVLPLTQPVGPINRPVGPGVL 419
                  +    V P   P G   ++  T+ +    TV P   P T    P   P+     
Sbjct: 3897 PTTTPITTTTTVTPTPTPTG--TQTPTTTPITTTTTVTPTPTP-TGTQTPTTTPITT-TT 3952

Query: 420  PVSPSVTPGVLQAVSPGVLSVSRAVPSGVLPAGQMTPAGQ--MTPAGVIPGQTATSGVLP 477
             V+P+ TP   Q  +   ++ +  V     P G  TP      T   V P  T T    P
Sbjct: 3953 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 4012

Query: 478  TGQMVQSGVLPVGQTAPSRVLPPGQTAPLRVISA--GQVVPSGLLSPNQT-VSSSAVVPV 534
            T   + +         P+    P  T P+   +       P+G  +P  T ++++  V  
Sbjct: 4013 TTTPITTTTTVTPTPTPTGTQTP-TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 4071

Query: 535  NQGVNSGVLQLSQPVVSGVLPVGQPVRPGVLQLNQT---VGTNILPVNQPVRPGASQNTT 591
                       + P+ +       P   G      T     T + P   P        T 
Sbjct: 4072 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 4131

Query: 592  FLTSGSILRQLIPTGKQVNGIPTYTLAPVSVTLPVPPGGLATVAPPQMPIQLLPSGAAAP 651
              T+ ++     PTG Q    PT T    + T+   P    T  P   PI    +    P
Sbjct: 4132 ITTTTTVTPTPTPTGTQT---PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 4188

Query: 652  M-AGSMPGMPS 661
               G+  G P+
Sbjct: 4189 TPTGTQTGPPT 4199



 Score = 50.1 bits (118), Expect = 1e-05
 Identities = 93/416 (22%), Positives = 127/416 (30%), Gaps = 49/416 (11%)

Query: 258  TGLLKQTHIAPKPAAHLAAPANGSAPSAPAQPPCFHLALPQNSPSPAAGQPVTVAQGAPG 317
            T  L  T     P      P   + PS P   P          P+     P T     P 
Sbjct: 1514 TTTLPPTTTPSPPTTTTTTPPPTTTPSPPTTTPI-------TPPTSTTTLPPTTTPSPPP 1566

Query: 318  SLTHSPPAAGQSHMTLVSSPLPVGQNSLTLQPPAPQPVFLSHGVPLHQSVNPP--VLPLS 375
            + T +PP          ++P P    + T  PP   P       P   +  PP    P  
Sbjct: 1567 TTTTTPPPTTTPSPPTTTTPSP-PTITTTTPPPTTTP-----SPPTTTTTTPPPTTTPSP 1620

Query: 376  QPVGPVNKSVGTSVLPINQTVRPGVLPLTQPVGPINRPVGPGVLPVSPSVT-----PGVL 430
                P+     T+ LP   T  P     T P  P   P  P     SP +T     P   
Sbjct: 1621 PTTTPITPPTSTTTLPPTTTPSPPPTTTTTP-PPTTTPSPPTTTTPSPPITTTTTPPPTT 1679

Query: 431  QAVSPGVLSVSRAVPSGVLPAGQMTPAGQMTPAGVIPGQTATSGVLPTGQMVQS-GVLPV 489
               SP   + S    +   P+   TP+  +T     P  T T    PT     S    P 
Sbjct: 1680 TPSSPITTTPSPPTTTMTTPSPTTTPSSPITTT-TTPSSTTTPSPPPTTMTTPSPTTTPS 1738

Query: 490  GQTAPSRVLPPGQT-APLRVISAGQVVPSGLLSP-NQTVSSSAVVPV---NQGVNSGVLQ 544
              T     LPP  T +PL        +     SP + T  ++  VP+      ++SG   
Sbjct: 1739 PPTTTMTTLPPTTTSSPLTTTPLPPSITPPTFSPFSTTTPTTPCVPLCNWTGWLDSGKPN 1798

Query: 545  LSQPVVSGVLPVGQPVRPG----------------VLQLNQT----VGTNILPVNQPVRP 584
              +P     L +G    PG                + QL QT    V   ++  N+  +P
Sbjct: 1799 FHKPGGDTEL-IGDVCGPGWAANISCRATMYPDVPIGQLGQTVVCDVSVGLICKNEDQKP 1857

Query: 585  GASQNTTFLTSGSILRQLIPTGKQVNGIPTYTLAPVSVTLPVPPGGLATVAPPQMP 640
            G      F  +  I  Q      Q   + T T    +     P     TV P   P
Sbjct: 1858 GGVIPMAFCLNYEINVQCCECVTQPTTMTTTTTENPTPPTTTPITTTTTVTPTPTP 1913



 Score = 50.1 bits (118), Expect = 1e-05
 Identities = 84/424 (19%), Positives = 137/424 (32%), Gaps = 47/424 (11%)

Query: 258  TGLLKQTHIAPKPAAHLAAPANGSAPSAPAQPPCFHLALPQNSPSPAAGQ-PVTVAQGAP 316
            T +   T + P P          +    P   P         +P+P   Q P T      
Sbjct: 3900 TPITTTTTVTPTPTP--------TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 3951

Query: 317  GSLTHSPPAAGQ---------SHMTLVSSPLPVGQNSLTLQP--------PAPQPVFLSH 359
             ++T +P   G          +  T+  +P P G  + T  P        P P P     
Sbjct: 3952 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 4011

Query: 360  GVPLHQSVNPPVLPLSQPVGPVNKSVGTSVLPINQTVRPGVLPLTQPVGPINRPVGPGVL 419
                  +    V P   P G   ++  T+ +    TV P   P T    P   P+     
Sbjct: 4012 PTTTPITTTTTVTPTPTPTG--TQTPTTTPITTTTTVTPTPTP-TGTQTPTTTPITT-TT 4067

Query: 420  PVSPSVTPGVLQAVSPGVLSVSRAVPSGVLPAGQMTPAGQMTPAGVIPGQTATSGVLPTG 479
             V+P+ TP   Q  +   ++ +  V     P G  TP    T   +    T T    PTG
Sbjct: 4068 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP----TTTPITTTTTVTPTPTPTG 4123

Query: 480  QMVQSGVLPVGQTAPSRVLPPGQTAPLRVISAGQVVPSGLLSPNQTVSSSAVVPVNQGVN 539
                +   P+  T  + V P       +  +   +  +  ++P  T + +   P    + 
Sbjct: 4124 TQTPT-TTPI--TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-PTTTPIT 4179

Query: 540  SGVLQLSQPVVSGVLPVGQPVRPGVLQLNQTVGTNILPVNQPVRPGASQNTTFLTSGSIL 599
            +       P  +G    G P       + +   +N  P +   +   S ++    S ++L
Sbjct: 4180 TTTTVTPTPTPTGT-QTGPPTHTSTAPIAELTTSNPPPESSTPQTSRSTSSPLTESTTLL 4238

Query: 600  RQLIPTGKQVNGIPTYTLAPVSVTLPVPPGGLATVAPPQMPIQLLPSGAAAPMAGSMPGM 659
              L P  +      T T  P + T P    G  T++PP        S    P  G+  G 
Sbjct: 4239 STLPPAIEM-----TSTAPPSTPTAPTTTSGGHTLSPPP---STTTSPPGTPTRGTTTGS 4290

Query: 660  PSPP 663
             S P
Sbjct: 4291 SSAP 4294



 Score = 49.3 bits (116), Expect = 2e-05
 Identities = 83/410 (20%), Positives = 127/410 (30%), Gaps = 42/410 (10%)

Query: 258  TGLLKQTHIAPKPAAHLAAPANGSAPSAPAQPPCFHLALPQNSPSPAAGQ-PVTVAQGAP 316
            T +   T + P P          +    P   P         +P+P   Q P T      
Sbjct: 1922 TPITTTTTVTPTPTP--------TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 1973

Query: 317  GSLTHSPPAAGQ---------SHMTLVSSPLPVGQNSLTLQP--------PAPQPVFLSH 359
             ++T +P   G          +  T+  +P P G  + T  P        P P P     
Sbjct: 1974 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 2033

Query: 360  GVPLHQSVNPPVLPLSQPVGPVNKSVGTSVLPINQTVRPGVLPLTQPVGPINRPVGPGVL 419
                  +    V P   P G   ++  T+ +    TV P   P T    P   P+     
Sbjct: 2034 PTTTPITTTTTVTPTPTPTG--TQTPTTTPITTTTTVTPTPTP-TGTQTPTTTPITT-TT 2089

Query: 420  PVSPSVTPGVLQAVSPGVLSVSRAVPSGVLPAGQMTPAGQ--MTPAGVIPGQTATSGVLP 477
             V+P+ TP   Q  +   ++ +  V     P G  TP      T   V P  T T    P
Sbjct: 2090 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 2149

Query: 478  TGQMVQSGVLPVGQTAPSRVLPPGQTAPLRVISA--GQVVPSGLLSPNQT-VSSSAVVPV 534
            T   + +         P+    P  T P+   +       P+G  +P  T ++++  V  
Sbjct: 2150 TTTPITTTTTVTPTPTPTGTQTP-TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 2208

Query: 535  NQGVNSGVLQLSQPVVSGVLPVGQPVRPGVLQLNQT---VGTNILPVNQPVRPGASQNTT 591
                       + P+ +       P   G      T     T + P   P        T 
Sbjct: 2209 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2268

Query: 592  FLTSGSILRQLIPTGKQVNGIPTYTLAPVSVTLPVPPGGLATVAPPQMPI 641
              T+ ++     PTG Q    PT T    + T+   P    T  P   PI
Sbjct: 2269 ITTTTTVTPTPTPTGTQT---PTTTPITTTTTVTPTPTPTGTQTPTTTPI 2315



 Score = 49.3 bits (116), Expect = 2e-05
 Identities = 83/410 (20%), Positives = 127/410 (30%), Gaps = 42/410 (10%)

Query: 258  TGLLKQTHIAPKPAAHLAAPANGSAPSAPAQPPCFHLALPQNSPSPAAGQ-PVTVAQGAP 316
            T +   T + P P          +    P   P         +P+P   Q P T      
Sbjct: 1945 TPITTTTTVTPTPTP--------TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 1996

Query: 317  GSLTHSPPAAGQ---------SHMTLVSSPLPVGQNSLTLQP--------PAPQPVFLSH 359
             ++T +P   G          +  T+  +P P G  + T  P        P P P     
Sbjct: 1997 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 2056

Query: 360  GVPLHQSVNPPVLPLSQPVGPVNKSVGTSVLPINQTVRPGVLPLTQPVGPINRPVGPGVL 419
                  +    V P   P G   ++  T+ +    TV P   P T    P   P+     
Sbjct: 2057 PTTTPITTTTTVTPTPTPTG--TQTPTTTPITTTTTVTPTPTP-TGTQTPTTTPITT-TT 2112

Query: 420  PVSPSVTPGVLQAVSPGVLSVSRAVPSGVLPAGQMTPAGQ--MTPAGVIPGQTATSGVLP 477
             V+P+ TP   Q  +   ++ +  V     P G  TP      T   V P  T T    P
Sbjct: 2113 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 2172

Query: 478  TGQMVQSGVLPVGQTAPSRVLPPGQTAPLRVISA--GQVVPSGLLSPNQT-VSSSAVVPV 534
            T   + +         P+    P  T P+   +       P+G  +P  T ++++  V  
Sbjct: 2173 TTTPITTTTTVTPTPTPTGTQTP-TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 2231

Query: 535  NQGVNSGVLQLSQPVVSGVLPVGQPVRPGVLQLNQT---VGTNILPVNQPVRPGASQNTT 591
                       + P+ +       P   G      T     T + P   P        T 
Sbjct: 2232 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2291

Query: 592  FLTSGSILRQLIPTGKQVNGIPTYTLAPVSVTLPVPPGGLATVAPPQMPI 641
              T+ ++     PTG Q    PT T    + T+   P    T  P   PI
Sbjct: 2292 ITTTTTVTPTPTPTGTQT---PTTTPITTTTTVTPTPTPTGTQTPTTTPI 2338



 Score = 49.3 bits (116), Expect = 2e-05
 Identities = 83/410 (20%), Positives = 127/410 (30%), Gaps = 42/410 (10%)

Query: 258  TGLLKQTHIAPKPAAHLAAPANGSAPSAPAQPPCFHLALPQNSPSPAAGQ-PVTVAQGAP 316
            T +   T + P P          +    P   P         +P+P   Q P T      
Sbjct: 1968 TPITTTTTVTPTPTP--------TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 2019

Query: 317  GSLTHSPPAAGQ---------SHMTLVSSPLPVGQNSLTLQP--------PAPQPVFLSH 359
             ++T +P   G          +  T+  +P P G  + T  P        P P P     
Sbjct: 2020 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 2079

Query: 360  GVPLHQSVNPPVLPLSQPVGPVNKSVGTSVLPINQTVRPGVLPLTQPVGPINRPVGPGVL 419
                  +    V P   P G   ++  T+ +    TV P   P T    P   P+     
Sbjct: 2080 PTTTPITTTTTVTPTPTPTG--TQTPTTTPITTTTTVTPTPTP-TGTQTPTTTPITT-TT 2135

Query: 420  PVSPSVTPGVLQAVSPGVLSVSRAVPSGVLPAGQMTPAGQ--MTPAGVIPGQTATSGVLP 477
             V+P+ TP   Q  +   ++ +  V     P G  TP      T   V P  T T    P
Sbjct: 2136 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 2195

Query: 478  TGQMVQSGVLPVGQTAPSRVLPPGQTAPLRVISA--GQVVPSGLLSPNQT-VSSSAVVPV 534
            T   + +         P+    P  T P+   +       P+G  +P  T ++++  V  
Sbjct: 2196 TTTPITTTTTVTPTPTPTGTQTP-TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 2254

Query: 535  NQGVNSGVLQLSQPVVSGVLPVGQPVRPGVLQLNQT---VGTNILPVNQPVRPGASQNTT 591
                       + P+ +       P   G      T     T + P   P        T 
Sbjct: 2255 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2314

Query: 592  FLTSGSILRQLIPTGKQVNGIPTYTLAPVSVTLPVPPGGLATVAPPQMPI 641
              T+ ++     PTG Q    PT T    + T+   P    T  P   PI
Sbjct: 2315 ITTTTTVTPTPTPTGTQT---PTTTPITTTTTVTPTPTPTGTQTPTTTPI 2361



 Score = 49.3 bits (116), Expect = 2e-05
 Identities = 83/410 (20%), Positives = 127/410 (30%), Gaps = 42/410 (10%)

Query: 258  TGLLKQTHIAPKPAAHLAAPANGSAPSAPAQPPCFHLALPQNSPSPAAGQ-PVTVAQGAP 316
            T +   T + P P          +    P   P         +P+P   Q P T      
Sbjct: 1991 TPITTTTTVTPTPTP--------TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 2042

Query: 317  GSLTHSPPAAGQ---------SHMTLVSSPLPVGQNSLTLQP--------PAPQPVFLSH 359
             ++T +P   G          +  T+  +P P G  + T  P        P P P     
Sbjct: 2043 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 2102

Query: 360  GVPLHQSVNPPVLPLSQPVGPVNKSVGTSVLPINQTVRPGVLPLTQPVGPINRPVGPGVL 419
                  +    V P   P G   ++  T+ +    TV P   P T    P   P+     
Sbjct: 2103 PTTTPITTTTTVTPTPTPTG--TQTPTTTPITTTTTVTPTPTP-TGTQTPTTTPITT-TT 2158

Query: 420  PVSPSVTPGVLQAVSPGVLSVSRAVPSGVLPAGQMTPAGQ--MTPAGVIPGQTATSGVLP 477
             V+P+ TP   Q  +   ++ +  V     P G  TP      T   V P  T T    P
Sbjct: 2159 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 2218

Query: 478  TGQMVQSGVLPVGQTAPSRVLPPGQTAPLRVISA--GQVVPSGLLSPNQT-VSSSAVVPV 534
            T   + +         P+    P  T P+   +       P+G  +P  T ++++  V  
Sbjct: 2219 TTTPITTTTTVTPTPTPTGTQTP-TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 2277

Query: 535  NQGVNSGVLQLSQPVVSGVLPVGQPVRPGVLQLNQT---VGTNILPVNQPVRPGASQNTT 591
                       + P+ +       P   G      T     T + P   P        T 
Sbjct: 2278 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2337

Query: 592  FLTSGSILRQLIPTGKQVNGIPTYTLAPVSVTLPVPPGGLATVAPPQMPI 641
              T+ ++     PTG Q    PT T    + T+   P    T  P   PI
Sbjct: 2338 ITTTTTVTPTPTPTGTQT---PTTTPITTTTTVTPTPTPTGTQTPTTTPI 2384



 Score = 49.3 bits (116), Expect = 2e-05
 Identities = 83/410 (20%), Positives = 127/410 (30%), Gaps = 42/410 (10%)

Query: 258  TGLLKQTHIAPKPAAHLAAPANGSAPSAPAQPPCFHLALPQNSPSPAAGQ-PVTVAQGAP 316
            T +   T + P P          +    P   P         +P+P   Q P T      
Sbjct: 2014 TPITTTTTVTPTPTP--------TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 2065

Query: 317  GSLTHSPPAAGQ---------SHMTLVSSPLPVGQNSLTLQP--------PAPQPVFLSH 359
             ++T +P   G          +  T+  +P P G  + T  P        P P P     
Sbjct: 2066 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 2125

Query: 360  GVPLHQSVNPPVLPLSQPVGPVNKSVGTSVLPINQTVRPGVLPLTQPVGPINRPVGPGVL 419
                  +    V P   P G   ++  T+ +    TV P   P T    P   P+     
Sbjct: 2126 PTTTPITTTTTVTPTPTPTG--TQTPTTTPITTTTTVTPTPTP-TGTQTPTTTPITT-TT 2181

Query: 420  PVSPSVTPGVLQAVSPGVLSVSRAVPSGVLPAGQMTPAGQ--MTPAGVIPGQTATSGVLP 477
             V+P+ TP   Q  +   ++ +  V     P G  TP      T   V P  T T    P
Sbjct: 2182 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 2241

Query: 478  TGQMVQSGVLPVGQTAPSRVLPPGQTAPLRVISA--GQVVPSGLLSPNQT-VSSSAVVPV 534
            T   + +         P+    P  T P+   +       P+G  +P  T ++++  V  
Sbjct: 2242 TTTPITTTTTVTPTPTPTGTQTP-TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 2300

Query: 535  NQGVNSGVLQLSQPVVSGVLPVGQPVRPGVLQLNQT---VGTNILPVNQPVRPGASQNTT 591
                       + P+ +       P   G      T     T + P   P        T 
Sbjct: 2301 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2360

Query: 592  FLTSGSILRQLIPTGKQVNGIPTYTLAPVSVTLPVPPGGLATVAPPQMPI 641
              T+ ++     PTG Q    PT T    + T+   P    T  P   PI
Sbjct: 2361 ITTTTTVTPTPTPTGTQT---PTTTPITTTTTVTPTPTPTGTQTPTTTPI 2407



 Score = 49.3 bits (116), Expect = 2e-05
 Identities = 83/410 (20%), Positives = 127/410 (30%), Gaps = 42/410 (10%)

Query: 258  TGLLKQTHIAPKPAAHLAAPANGSAPSAPAQPPCFHLALPQNSPSPAAGQ-PVTVAQGAP 316
            T +   T + P P          +    P   P         +P+P   Q P T      
Sbjct: 2037 TPITTTTTVTPTPTP--------TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 2088

Query: 317  GSLTHSPPAAGQ---------SHMTLVSSPLPVGQNSLTLQP--------PAPQPVFLSH 359
             ++T +P   G          +  T+  +P P G  + T  P        P P P     
Sbjct: 2089 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 2148

Query: 360  GVPLHQSVNPPVLPLSQPVGPVNKSVGTSVLPINQTVRPGVLPLTQPVGPINRPVGPGVL 419
                  +    V P   P G   ++  T+ +    TV P   P T    P   P+     
Sbjct: 2149 PTTTPITTTTTVTPTPTPTG--TQTPTTTPITTTTTVTPTPTP-TGTQTPTTTPITT-TT 2204

Query: 420  PVSPSVTPGVLQAVSPGVLSVSRAVPSGVLPAGQMTPAGQ--MTPAGVIPGQTATSGVLP 477
             V+P+ TP   Q  +   ++ +  V     P G  TP      T   V P  T T    P
Sbjct: 2205 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 2264

Query: 478  TGQMVQSGVLPVGQTAPSRVLPPGQTAPLRVISA--GQVVPSGLLSPNQT-VSSSAVVPV 534
            T   + +         P+    P  T P+   +       P+G  +P  T ++++  V  
Sbjct: 2265 TTTPITTTTTVTPTPTPTGTQTP-TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 2323

Query: 535  NQGVNSGVLQLSQPVVSGVLPVGQPVRPGVLQLNQT---VGTNILPVNQPVRPGASQNTT 591
                       + P+ +       P   G      T     T + P   P        T 
Sbjct: 2324 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2383

Query: 592  FLTSGSILRQLIPTGKQVNGIPTYTLAPVSVTLPVPPGGLATVAPPQMPI 641
              T+ ++     PTG Q    PT T    + T+   P    T  P   PI
Sbjct: 2384 ITTTTTVTPTPTPTGTQT---PTTTPITTTTTVTPTPTPTGTQTPTTTPI 2430



 Score = 49.3 bits (116), Expect = 2e-05
 Identities = 83/410 (20%), Positives = 127/410 (30%), Gaps = 42/410 (10%)

Query: 258  TGLLKQTHIAPKPAAHLAAPANGSAPSAPAQPPCFHLALPQNSPSPAAGQ-PVTVAQGAP 316
            T +   T + P P          +    P   P         +P+P   Q P T      
Sbjct: 2060 TPITTTTTVTPTPTP--------TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 2111

Query: 317  GSLTHSPPAAGQ---------SHMTLVSSPLPVGQNSLTLQP--------PAPQPVFLSH 359
             ++T +P   G          +  T+  +P P G  + T  P        P P P     
Sbjct: 2112 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 2171

Query: 360  GVPLHQSVNPPVLPLSQPVGPVNKSVGTSVLPINQTVRPGVLPLTQPVGPINRPVGPGVL 419
                  +    V P   P G   ++  T+ +    TV P   P T    P   P+     
Sbjct: 2172 PTTTPITTTTTVTPTPTPTG--TQTPTTTPITTTTTVTPTPTP-TGTQTPTTTPITT-TT 2227

Query: 420  PVSPSVTPGVLQAVSPGVLSVSRAVPSGVLPAGQMTPAGQ--MTPAGVIPGQTATSGVLP 477
             V+P+ TP   Q  +   ++ +  V     P G  TP      T   V P  T T    P
Sbjct: 2228 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 2287

Query: 478  TGQMVQSGVLPVGQTAPSRVLPPGQTAPLRVISA--GQVVPSGLLSPNQT-VSSSAVVPV 534
            T   + +         P+    P  T P+   +       P+G  +P  T ++++  V  
Sbjct: 2288 TTTPITTTTTVTPTPTPTGTQTP-TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 2346

Query: 535  NQGVNSGVLQLSQPVVSGVLPVGQPVRPGVLQLNQT---VGTNILPVNQPVRPGASQNTT 591
                       + P+ +       P   G      T     T + P   P        T 
Sbjct: 2347 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2406

Query: 592  FLTSGSILRQLIPTGKQVNGIPTYTLAPVSVTLPVPPGGLATVAPPQMPI 641
              T+ ++     PTG Q    PT T    + T+   P    T  P   PI
Sbjct: 2407 ITTTTTVTPTPTPTGTQT---PTTTPITTTTTVTPTPTPTGTQTPTTTPI 2453



 Score = 49.3 bits (116), Expect = 2e-05
 Identities = 83/410 (20%), Positives = 127/410 (30%), Gaps = 42/410 (10%)

Query: 258  TGLLKQTHIAPKPAAHLAAPANGSAPSAPAQPPCFHLALPQNSPSPAAGQ-PVTVAQGAP 316
            T +   T + P P          +    P   P         +P+P   Q P T      
Sbjct: 2083 TPITTTTTVTPTPTP--------TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 2134

Query: 317  GSLTHSPPAAGQ---------SHMTLVSSPLPVGQNSLTLQP--------PAPQPVFLSH 359
             ++T +P   G          +  T+  +P P G  + T  P        P P P     
Sbjct: 2135 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 2194

Query: 360  GVPLHQSVNPPVLPLSQPVGPVNKSVGTSVLPINQTVRPGVLPLTQPVGPINRPVGPGVL 419
                  +    V P   P G   ++  T+ +    TV P   P T    P   P+     
Sbjct: 2195 PTTTPITTTTTVTPTPTPTG--TQTPTTTPITTTTTVTPTPTP-TGTQTPTTTPITT-TT 2250

Query: 420  PVSPSVTPGVLQAVSPGVLSVSRAVPSGVLPAGQMTPAGQ--MTPAGVIPGQTATSGVLP 477
             V+P+ TP   Q  +   ++ +  V     P G  TP      T   V P  T T    P
Sbjct: 2251 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 2310

Query: 478  TGQMVQSGVLPVGQTAPSRVLPPGQTAPLRVISA--GQVVPSGLLSPNQT-VSSSAVVPV 534
            T   + +         P+    P  T P+   +       P+G  +P  T ++++  V  
Sbjct: 2311 TTTPITTTTTVTPTPTPTGTQTP-TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 2369

Query: 535  NQGVNSGVLQLSQPVVSGVLPVGQPVRPGVLQLNQT---VGTNILPVNQPVRPGASQNTT 591
                       + P+ +       P   G      T     T + P   P        T 
Sbjct: 2370 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2429

Query: 592  FLTSGSILRQLIPTGKQVNGIPTYTLAPVSVTLPVPPGGLATVAPPQMPI 641
              T+ ++     PTG Q    PT T    + T+   P    T  P   PI
Sbjct: 2430 ITTTTTVTPTPTPTGTQT---PTTTPITTTTTVTPTPTPTGTQTPTTTPI 2476



 Score = 49.3 bits (116), Expect = 2e-05
 Identities = 83/410 (20%), Positives = 127/410 (30%), Gaps = 42/410 (10%)

Query: 258  TGLLKQTHIAPKPAAHLAAPANGSAPSAPAQPPCFHLALPQNSPSPAAGQ-PVTVAQGAP 316
            T +   T + P P          +    P   P         +P+P   Q P T      
Sbjct: 2106 TPITTTTTVTPTPTP--------TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 2157

Query: 317  GSLTHSPPAAGQ---------SHMTLVSSPLPVGQNSLTLQP--------PAPQPVFLSH 359
             ++T +P   G          +  T+  +P P G  + T  P        P P P     
Sbjct: 2158 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 2217

Query: 360  GVPLHQSVNPPVLPLSQPVGPVNKSVGTSVLPINQTVRPGVLPLTQPVGPINRPVGPGVL 419
                  +    V P   P G   ++  T+ +    TV P   P T    P   P+     
Sbjct: 2218 PTTTPITTTTTVTPTPTPTG--TQTPTTTPITTTTTVTPTPTP-TGTQTPTTTPITT-TT 2273

Query: 420  PVSPSVTPGVLQAVSPGVLSVSRAVPSGVLPAGQMTPAGQ--MTPAGVIPGQTATSGVLP 477
             V+P+ TP   Q  +   ++ +  V     P G  TP      T   V P  T T    P
Sbjct: 2274 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 2333

Query: 478  TGQMVQSGVLPVGQTAPSRVLPPGQTAPLRVISA--GQVVPSGLLSPNQT-VSSSAVVPV 534
            T   + +         P+    P  T P+   +       P+G  +P  T ++++  V  
Sbjct: 2334 TTTPITTTTTVTPTPTPTGTQTP-TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 2392

Query: 535  NQGVNSGVLQLSQPVVSGVLPVGQPVRPGVLQLNQT---VGTNILPVNQPVRPGASQNTT 591
                       + P+ +       P   G      T     T + P   P        T 
Sbjct: 2393 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2452

Query: 592  FLTSGSILRQLIPTGKQVNGIPTYTLAPVSVTLPVPPGGLATVAPPQMPI 641
              T+ ++     PTG Q    PT T    + T+   P    T  P   PI
Sbjct: 2453 ITTTTTVTPTPTPTGTQT---PTTTPITTTTTVTPTPTPTGTQTPTTTPI 2499



 Score = 49.3 bits (116), Expect = 2e-05
 Identities = 83/410 (20%), Positives = 127/410 (30%), Gaps = 42/410 (10%)

Query: 258  TGLLKQTHIAPKPAAHLAAPANGSAPSAPAQPPCFHLALPQNSPSPAAGQ-PVTVAQGAP 316
            T +   T + P P          +    P   P         +P+P   Q P T      
Sbjct: 2129 TPITTTTTVTPTPTP--------TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 2180

Query: 317  GSLTHSPPAAGQ---------SHMTLVSSPLPVGQNSLTLQP--------PAPQPVFLSH 359
             ++T +P   G          +  T+  +P P G  + T  P        P P P     
Sbjct: 2181 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 2240

Query: 360  GVPLHQSVNPPVLPLSQPVGPVNKSVGTSVLPINQTVRPGVLPLTQPVGPINRPVGPGVL 419
                  +    V P   P G   ++  T+ +    TV P   P T    P   P+     
Sbjct: 2241 PTTTPITTTTTVTPTPTPTG--TQTPTTTPITTTTTVTPTPTP-TGTQTPTTTPITT-TT 2296

Query: 420  PVSPSVTPGVLQAVSPGVLSVSRAVPSGVLPAGQMTPAGQ--MTPAGVIPGQTATSGVLP 477
             V+P+ TP   Q  +   ++ +  V     P G  TP      T   V P  T T    P
Sbjct: 2297 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 2356

Query: 478  TGQMVQSGVLPVGQTAPSRVLPPGQTAPLRVISA--GQVVPSGLLSPNQT-VSSSAVVPV 534
            T   + +         P+    P  T P+   +       P+G  +P  T ++++  V  
Sbjct: 2357 TTTPITTTTTVTPTPTPTGTQTP-TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 2415

Query: 535  NQGVNSGVLQLSQPVVSGVLPVGQPVRPGVLQLNQT---VGTNILPVNQPVRPGASQNTT 591
                       + P+ +       P   G      T     T + P   P        T 
Sbjct: 2416 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2475

Query: 592  FLTSGSILRQLIPTGKQVNGIPTYTLAPVSVTLPVPPGGLATVAPPQMPI 641
              T+ ++     PTG Q    PT T    + T+   P    T  P   PI
Sbjct: 2476 ITTTTTVTPTPTPTGTQT---PTTTPITTTTTVTPTPTPTGTQTPTTTPI 2522



 Score = 49.3 bits (116), Expect = 2e-05
 Identities = 83/410 (20%), Positives = 127/410 (30%), Gaps = 42/410 (10%)

Query: 258  TGLLKQTHIAPKPAAHLAAPANGSAPSAPAQPPCFHLALPQNSPSPAAGQ-PVTVAQGAP 316
            T +   T + P P          +    P   P         +P+P   Q P T      
Sbjct: 2152 TPITTTTTVTPTPTP--------TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 2203

Query: 317  GSLTHSPPAAGQ---------SHMTLVSSPLPVGQNSLTLQP--------PAPQPVFLSH 359
             ++T +P   G          +  T+  +P P G  + T  P        P P P     
Sbjct: 2204 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 2263

Query: 360  GVPLHQSVNPPVLPLSQPVGPVNKSVGTSVLPINQTVRPGVLPLTQPVGPINRPVGPGVL 419
                  +    V P   P G   ++  T+ +    TV P   P T    P   P+     
Sbjct: 2264 PTTTPITTTTTVTPTPTPTG--TQTPTTTPITTTTTVTPTPTP-TGTQTPTTTPITT-TT 2319

Query: 420  PVSPSVTPGVLQAVSPGVLSVSRAVPSGVLPAGQMTPAGQ--MTPAGVIPGQTATSGVLP 477
             V+P+ TP   Q  +   ++ +  V     P G  TP      T   V P  T T    P
Sbjct: 2320 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 2379

Query: 478  TGQMVQSGVLPVGQTAPSRVLPPGQTAPLRVISA--GQVVPSGLLSPNQT-VSSSAVVPV 534
            T   + +         P+    P  T P+   +       P+G  +P  T ++++  V  
Sbjct: 2380 TTTPITTTTTVTPTPTPTGTQTP-TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 2438

Query: 535  NQGVNSGVLQLSQPVVSGVLPVGQPVRPGVLQLNQT---VGTNILPVNQPVRPGASQNTT 591
                       + P+ +       P   G      T     T + P   P        T 
Sbjct: 2439 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2498

Query: 592  FLTSGSILRQLIPTGKQVNGIPTYTLAPVSVTLPVPPGGLATVAPPQMPI 641
              T+ ++     PTG Q    PT T    + T+   P    T  P   PI
Sbjct: 2499 ITTTTTVTPTPTPTGTQT---PTTTPITTTTTVTPTPTPTGTQTPTTTPI 2545



 Score = 49.3 bits (116), Expect = 2e-05
 Identities = 83/410 (20%), Positives = 127/410 (30%), Gaps = 42/410 (10%)

Query: 258  TGLLKQTHIAPKPAAHLAAPANGSAPSAPAQPPCFHLALPQNSPSPAAGQ-PVTVAQGAP 316
            T +   T + P P          +    P   P         +P+P   Q P T      
Sbjct: 2175 TPITTTTTVTPTPTP--------TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 2226

Query: 317  GSLTHSPPAAGQ---------SHMTLVSSPLPVGQNSLTLQP--------PAPQPVFLSH 359
             ++T +P   G          +  T+  +P P G  + T  P        P P P     
Sbjct: 2227 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 2286

Query: 360  GVPLHQSVNPPVLPLSQPVGPVNKSVGTSVLPINQTVRPGVLPLTQPVGPINRPVGPGVL 419
                  +    V P   P G   ++  T+ +    TV P   P T    P   P+     
Sbjct: 2287 PTTTPITTTTTVTPTPTPTG--TQTPTTTPITTTTTVTPTPTP-TGTQTPTTTPITT-TT 2342

Query: 420  PVSPSVTPGVLQAVSPGVLSVSRAVPSGVLPAGQMTPAGQ--MTPAGVIPGQTATSGVLP 477
             V+P+ TP   Q  +   ++ +  V     P G  TP      T   V P  T T    P
Sbjct: 2343 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 2402

Query: 478  TGQMVQSGVLPVGQTAPSRVLPPGQTAPLRVISA--GQVVPSGLLSPNQT-VSSSAVVPV 534
            T   + +         P+    P  T P+   +       P+G  +P  T ++++  V  
Sbjct: 2403 TTTPITTTTTVTPTPTPTGTQTP-TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 2461

Query: 535  NQGVNSGVLQLSQPVVSGVLPVGQPVRPGVLQLNQT---VGTNILPVNQPVRPGASQNTT 591
                       + P+ +       P   G      T     T + P   P        T 
Sbjct: 2462 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2521

Query: 592  FLTSGSILRQLIPTGKQVNGIPTYTLAPVSVTLPVPPGGLATVAPPQMPI 641
              T+ ++     PTG Q    PT T    + T+   P    T  P   PI
Sbjct: 2522 ITTTTTVTPTPTPTGTQT---PTTTPITTTTTVTPTPTPTGTQTPTTTPI 2568



 Score = 49.3 bits (116), Expect = 2e-05
 Identities = 83/410 (20%), Positives = 127/410 (30%), Gaps = 42/410 (10%)

Query: 258  TGLLKQTHIAPKPAAHLAAPANGSAPSAPAQPPCFHLALPQNSPSPAAGQ-PVTVAQGAP 316
            T +   T + P P          +    P   P         +P+P   Q P T      
Sbjct: 2198 TPITTTTTVTPTPTP--------TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 2249

Query: 317  GSLTHSPPAAGQ---------SHMTLVSSPLPVGQNSLTLQP--------PAPQPVFLSH 359
             ++T +P   G          +  T+  +P P G  + T  P        P P P     
Sbjct: 2250 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 2309

Query: 360  GVPLHQSVNPPVLPLSQPVGPVNKSVGTSVLPINQTVRPGVLPLTQPVGPINRPVGPGVL 419
                  +    V P   P G   ++  T+ +    TV P   P T    P   P+     
Sbjct: 2310 PTTTPITTTTTVTPTPTPTG--TQTPTTTPITTTTTVTPTPTP-TGTQTPTTTPITT-TT 2365

Query: 420  PVSPSVTPGVLQAVSPGVLSVSRAVPSGVLPAGQMTPAGQ--MTPAGVIPGQTATSGVLP 477
             V+P+ TP   Q  +   ++ +  V     P G  TP      T   V P  T T    P
Sbjct: 2366 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 2425

Query: 478  TGQMVQSGVLPVGQTAPSRVLPPGQTAPLRVISA--GQVVPSGLLSPNQT-VSSSAVVPV 534
            T   + +         P+    P  T P+   +       P+G  +P  T ++++  V  
Sbjct: 2426 TTTPITTTTTVTPTPTPTGTQTP-TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 2484

Query: 535  NQGVNSGVLQLSQPVVSGVLPVGQPVRPGVLQLNQT---VGTNILPVNQPVRPGASQNTT 591
                       + P+ +       P   G      T     T + P   P        T 
Sbjct: 2485 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2544

Query: 592  FLTSGSILRQLIPTGKQVNGIPTYTLAPVSVTLPVPPGGLATVAPPQMPI 641
              T+ ++     PTG Q    PT T    + T+   P    T  P   PI
Sbjct: 2545 ITTTTTVTPTPTPTGTQT---PTTTPITTTTTVTPTPTPTGTQTPTTTPI 2591



 Score = 49.3 bits (116), Expect = 2e-05
 Identities = 83/410 (20%), Positives = 127/410 (30%), Gaps = 42/410 (10%)

Query: 258  TGLLKQTHIAPKPAAHLAAPANGSAPSAPAQPPCFHLALPQNSPSPAAGQ-PVTVAQGAP 316
            T +   T + P P          +    P   P         +P+P   Q P T      
Sbjct: 2221 TPITTTTTVTPTPTP--------TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 2272

Query: 317  GSLTHSPPAAGQ---------SHMTLVSSPLPVGQNSLTLQP--------PAPQPVFLSH 359
             ++T +P   G          +  T+  +P P G  + T  P        P P P     
Sbjct: 2273 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 2332

Query: 360  GVPLHQSVNPPVLPLSQPVGPVNKSVGTSVLPINQTVRPGVLPLTQPVGPINRPVGPGVL 419
                  +    V P   P G   ++  T+ +    TV P   P T    P   P+     
Sbjct: 2333 PTTTPITTTTTVTPTPTPTG--TQTPTTTPITTTTTVTPTPTP-TGTQTPTTTPITT-TT 2388

Query: 420  PVSPSVTPGVLQAVSPGVLSVSRAVPSGVLPAGQMTPAGQ--MTPAGVIPGQTATSGVLP 477
             V+P+ TP   Q  +   ++ +  V     P G  TP      T   V P  T T    P
Sbjct: 2389 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 2448

Query: 478  TGQMVQSGVLPVGQTAPSRVLPPGQTAPLRVISA--GQVVPSGLLSPNQT-VSSSAVVPV 534
            T   + +         P+    P  T P+   +       P+G  +P  T ++++  V  
Sbjct: 2449 TTTPITTTTTVTPTPTPTGTQTP-TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 2507

Query: 535  NQGVNSGVLQLSQPVVSGVLPVGQPVRPGVLQLNQT---VGTNILPVNQPVRPGASQNTT 591
                       + P+ +       P   G      T     T + P   P        T 
Sbjct: 2508 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2567

Query: 592  FLTSGSILRQLIPTGKQVNGIPTYTLAPVSVTLPVPPGGLATVAPPQMPI 641
              T+ ++     PTG Q    PT T    + T+   P    T  P   PI
Sbjct: 2568 ITTTTTVTPTPTPTGTQT---PTTTPITTTTTVTPTPTPTGTQTPTTTPI 2614



 Score = 49.3 bits (116), Expect = 2e-05
 Identities = 83/410 (20%), Positives = 127/410 (30%), Gaps = 42/410 (10%)

Query: 258  TGLLKQTHIAPKPAAHLAAPANGSAPSAPAQPPCFHLALPQNSPSPAAGQ-PVTVAQGAP 316
            T +   T + P P          +    P   P         +P+P   Q P T      
Sbjct: 2244 TPITTTTTVTPTPTP--------TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 2295

Query: 317  GSLTHSPPAAGQ---------SHMTLVSSPLPVGQNSLTLQP--------PAPQPVFLSH 359
             ++T +P   G          +  T+  +P P G  + T  P        P P P     
Sbjct: 2296 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 2355

Query: 360  GVPLHQSVNPPVLPLSQPVGPVNKSVGTSVLPINQTVRPGVLPLTQPVGPINRPVGPGVL 419
                  +    V P   P G   ++  T+ +    TV P   P T    P   P+     
Sbjct: 2356 PTTTPITTTTTVTPTPTPTG--TQTPTTTPITTTTTVTPTPTP-TGTQTPTTTPITT-TT 2411

Query: 420  PVSPSVTPGVLQAVSPGVLSVSRAVPSGVLPAGQMTPAGQ--MTPAGVIPGQTATSGVLP 477
             V+P+ TP   Q  +   ++ +  V     P G  TP      T   V P  T T    P
Sbjct: 2412 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 2471

Query: 478  TGQMVQSGVLPVGQTAPSRVLPPGQTAPLRVISA--GQVVPSGLLSPNQT-VSSSAVVPV 534
            T   + +         P+    P  T P+   +       P+G  +P  T ++++  V  
Sbjct: 2472 TTTPITTTTTVTPTPTPTGTQTP-TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 2530

Query: 535  NQGVNSGVLQLSQPVVSGVLPVGQPVRPGVLQLNQT---VGTNILPVNQPVRPGASQNTT 591
                       + P+ +       P   G      T     T + P   P        T 
Sbjct: 2531 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2590

Query: 592  FLTSGSILRQLIPTGKQVNGIPTYTLAPVSVTLPVPPGGLATVAPPQMPI 641
              T+ ++     PTG Q    PT T    + T+   P    T  P   PI
Sbjct: 2591 ITTTTTVTPTPTPTGTQT---PTTTPITTTTTVTPTPTPTGTQTPTTTPI 2637



 Score = 49.3 bits (116), Expect = 2e-05
 Identities = 83/410 (20%), Positives = 127/410 (30%), Gaps = 42/410 (10%)

Query: 258  TGLLKQTHIAPKPAAHLAAPANGSAPSAPAQPPCFHLALPQNSPSPAAGQ-PVTVAQGAP 316
            T +   T + P P          +    P   P         +P+P   Q P T      
Sbjct: 2267 TPITTTTTVTPTPTP--------TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 2318

Query: 317  GSLTHSPPAAGQ---------SHMTLVSSPLPVGQNSLTLQP--------PAPQPVFLSH 359
             ++T +P   G          +  T+  +P P G  + T  P        P P P     
Sbjct: 2319 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 2378

Query: 360  GVPLHQSVNPPVLPLSQPVGPVNKSVGTSVLPINQTVRPGVLPLTQPVGPINRPVGPGVL 419
                  +    V P   P G   ++  T+ +    TV P   P T    P   P+     
Sbjct: 2379 PTTTPITTTTTVTPTPTPTG--TQTPTTTPITTTTTVTPTPTP-TGTQTPTTTPITT-TT 2434

Query: 420  PVSPSVTPGVLQAVSPGVLSVSRAVPSGVLPAGQMTPAGQ--MTPAGVIPGQTATSGVLP 477
             V+P+ TP   Q  +   ++ +  V     P G  TP      T   V P  T T    P
Sbjct: 2435 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 2494

Query: 478  TGQMVQSGVLPVGQTAPSRVLPPGQTAPLRVISA--GQVVPSGLLSPNQT-VSSSAVVPV 534
            T   + +         P+    P  T P+   +       P+G  +P  T ++++  V  
Sbjct: 2495 TTTPITTTTTVTPTPTPTGTQTP-TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 2553

Query: 535  NQGVNSGVLQLSQPVVSGVLPVGQPVRPGVLQLNQT---VGTNILPVNQPVRPGASQNTT 591
                       + P+ +       P   G      T     T + P   P        T 
Sbjct: 2554 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2613

Query: 592  FLTSGSILRQLIPTGKQVNGIPTYTLAPVSVTLPVPPGGLATVAPPQMPI 641
              T+ ++     PTG Q    PT T    + T+   P    T  P   PI
Sbjct: 2614 ITTTTTVTPTPTPTGTQT---PTTTPITTTTTVTPTPTPTGTQTPTTTPI 2660



 Score = 49.3 bits (116), Expect = 2e-05
 Identities = 83/410 (20%), Positives = 127/410 (30%), Gaps = 42/410 (10%)

Query: 258  TGLLKQTHIAPKPAAHLAAPANGSAPSAPAQPPCFHLALPQNSPSPAAGQ-PVTVAQGAP 316
            T +   T + P P          +    P   P         +P+P   Q P T      
Sbjct: 2290 TPITTTTTVTPTPTP--------TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 2341

Query: 317  GSLTHSPPAAGQ---------SHMTLVSSPLPVGQNSLTLQP--------PAPQPVFLSH 359
             ++T +P   G          +  T+  +P P G  + T  P        P P P     
Sbjct: 2342 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 2401

Query: 360  GVPLHQSVNPPVLPLSQPVGPVNKSVGTSVLPINQTVRPGVLPLTQPVGPINRPVGPGVL 419
                  +    V P   P G   ++  T+ +    TV P   P T    P   P+     
Sbjct: 2402 PTTTPITTTTTVTPTPTPTG--TQTPTTTPITTTTTVTPTPTP-TGTQTPTTTPITT-TT 2457

Query: 420  PVSPSVTPGVLQAVSPGVLSVSRAVPSGVLPAGQMTPAGQ--MTPAGVIPGQTATSGVLP 477
             V+P+ TP   Q  +   ++ +  V     P G  TP      T   V P  T T    P
Sbjct: 2458 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 2517

Query: 478  TGQMVQSGVLPVGQTAPSRVLPPGQTAPLRVISA--GQVVPSGLLSPNQT-VSSSAVVPV 534
            T   + +         P+    P  T P+   +       P+G  +P  T ++++  V  
Sbjct: 2518 TTTPITTTTTVTPTPTPTGTQTP-TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 2576

Query: 535  NQGVNSGVLQLSQPVVSGVLPVGQPVRPGVLQLNQT---VGTNILPVNQPVRPGASQNTT 591
                       + P+ +       P   G      T     T + P   P        T 
Sbjct: 2577 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2636

Query: 592  FLTSGSILRQLIPTGKQVNGIPTYTLAPVSVTLPVPPGGLATVAPPQMPI 641
              T+ ++     PTG Q    PT T    + T+   P    T  P   PI
Sbjct: 2637 ITTTTTVTPTPTPTGTQT---PTTTPITTTTTVTPTPTPTGTQTPTTTPI 2683



 Score = 49.3 bits (116), Expect = 2e-05
 Identities = 83/410 (20%), Positives = 127/410 (30%), Gaps = 42/410 (10%)

Query: 258  TGLLKQTHIAPKPAAHLAAPANGSAPSAPAQPPCFHLALPQNSPSPAAGQ-PVTVAQGAP 316
            T +   T + P P          +    P   P         +P+P   Q P T      
Sbjct: 2313 TPITTTTTVTPTPTP--------TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 2364

Query: 317  GSLTHSPPAAGQ---------SHMTLVSSPLPVGQNSLTLQP--------PAPQPVFLSH 359
             ++T +P   G          +  T+  +P P G  + T  P        P P P     
Sbjct: 2365 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 2424

Query: 360  GVPLHQSVNPPVLPLSQPVGPVNKSVGTSVLPINQTVRPGVLPLTQPVGPINRPVGPGVL 419
                  +    V P   P G   ++  T+ +    TV P   P T    P   P+     
Sbjct: 2425 PTTTPITTTTTVTPTPTPTG--TQTPTTTPITTTTTVTPTPTP-TGTQTPTTTPITT-TT 2480

Query: 420  PVSPSVTPGVLQAVSPGVLSVSRAVPSGVLPAGQMTPAGQ--MTPAGVIPGQTATSGVLP 477
             V+P+ TP   Q  +   ++ +  V     P G  TP      T   V P  T T    P
Sbjct: 2481 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 2540

Query: 478  TGQMVQSGVLPVGQTAPSRVLPPGQTAPLRVISA--GQVVPSGLLSPNQT-VSSSAVVPV 534
            T   + +         P+    P  T P+   +       P+G  +P  T ++++  V  
Sbjct: 2541 TTTPITTTTTVTPTPTPTGTQTP-TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 2599

Query: 535  NQGVNSGVLQLSQPVVSGVLPVGQPVRPGVLQLNQT---VGTNILPVNQPVRPGASQNTT 591
                       + P+ +       P   G      T     T + P   P        T 
Sbjct: 2600 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2659

Query: 592  FLTSGSILRQLIPTGKQVNGIPTYTLAPVSVTLPVPPGGLATVAPPQMPI 641
              T+ ++     PTG Q    PT T    + T+   P    T  P   PI
Sbjct: 2660 ITTTTTVTPTPTPTGTQT---PTTTPITTTTTVTPTPTPTGTQTPTTTPI 2706



 Score = 49.3 bits (116), Expect = 2e-05
 Identities = 83/410 (20%), Positives = 127/410 (30%), Gaps = 42/410 (10%)

Query: 258  TGLLKQTHIAPKPAAHLAAPANGSAPSAPAQPPCFHLALPQNSPSPAAGQ-PVTVAQGAP 316
            T +   T + P P          +    P   P         +P+P   Q P T      
Sbjct: 2336 TPITTTTTVTPTPTP--------TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 2387

Query: 317  GSLTHSPPAAGQ---------SHMTLVSSPLPVGQNSLTLQP--------PAPQPVFLSH 359
             ++T +P   G          +  T+  +P P G  + T  P        P P P     
Sbjct: 2388 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 2447

Query: 360  GVPLHQSVNPPVLPLSQPVGPVNKSVGTSVLPINQTVRPGVLPLTQPVGPINRPVGPGVL 419
                  +    V P   P G   ++  T+ +    TV P   P T    P   P+     
Sbjct: 2448 PTTTPITTTTTVTPTPTPTG--TQTPTTTPITTTTTVTPTPTP-TGTQTPTTTPITT-TT 2503

Query: 420  PVSPSVTPGVLQAVSPGVLSVSRAVPSGVLPAGQMTPAGQ--MTPAGVIPGQTATSGVLP 477
             V+P+ TP   Q  +   ++ +  V     P G  TP      T   V P  T T    P
Sbjct: 2504 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 2563

Query: 478  TGQMVQSGVLPVGQTAPSRVLPPGQTAPLRVISA--GQVVPSGLLSPNQT-VSSSAVVPV 534
            T   + +         P+    P  T P+   +       P+G  +P  T ++++  V  
Sbjct: 2564 TTTPITTTTTVTPTPTPTGTQTP-TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 2622

Query: 535  NQGVNSGVLQLSQPVVSGVLPVGQPVRPGVLQLNQT---VGTNILPVNQPVRPGASQNTT 591
                       + P+ +       P   G      T     T + P   P        T 
Sbjct: 2623 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2682

Query: 592  FLTSGSILRQLIPTGKQVNGIPTYTLAPVSVTLPVPPGGLATVAPPQMPI 641
              T+ ++     PTG Q    PT T    + T+   P    T  P   PI
Sbjct: 2683 ITTTTTVTPTPTPTGTQT---PTTTPITTTTTVTPTPTPTGTQTPTTTPI 2729



 Score = 49.3 bits (116), Expect = 2e-05
 Identities = 83/410 (20%), Positives = 127/410 (30%), Gaps = 42/410 (10%)

Query: 258  TGLLKQTHIAPKPAAHLAAPANGSAPSAPAQPPCFHLALPQNSPSPAAGQ-PVTVAQGAP 316
            T +   T + P P          +    P   P         +P+P   Q P T      
Sbjct: 2359 TPITTTTTVTPTPTP--------TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 2410

Query: 317  GSLTHSPPAAGQ---------SHMTLVSSPLPVGQNSLTLQP--------PAPQPVFLSH 359
             ++T +P   G          +  T+  +P P G  + T  P        P P P     
Sbjct: 2411 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 2470

Query: 360  GVPLHQSVNPPVLPLSQPVGPVNKSVGTSVLPINQTVRPGVLPLTQPVGPINRPVGPGVL 419
                  +    V P   P G   ++  T+ +    TV P   P T    P   P+     
Sbjct: 2471 PTTTPITTTTTVTPTPTPTG--TQTPTTTPITTTTTVTPTPTP-TGTQTPTTTPITT-TT 2526

Query: 420  PVSPSVTPGVLQAVSPGVLSVSRAVPSGVLPAGQMTPAGQ--MTPAGVIPGQTATSGVLP 477
             V+P+ TP   Q  +   ++ +  V     P G  TP      T   V P  T T    P
Sbjct: 2527 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 2586

Query: 478  TGQMVQSGVLPVGQTAPSRVLPPGQTAPLRVISA--GQVVPSGLLSPNQT-VSSSAVVPV 534
            T   + +         P+    P  T P+   +       P+G  +P  T ++++  V  
Sbjct: 2587 TTTPITTTTTVTPTPTPTGTQTP-TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 2645

Query: 535  NQGVNSGVLQLSQPVVSGVLPVGQPVRPGVLQLNQT---VGTNILPVNQPVRPGASQNTT 591
                       + P+ +       P   G      T     T + P   P        T 
Sbjct: 2646 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2705

Query: 592  FLTSGSILRQLIPTGKQVNGIPTYTLAPVSVTLPVPPGGLATVAPPQMPI 641
              T+ ++     PTG Q    PT T    + T+   P    T  P   PI
Sbjct: 2706 ITTTTTVTPTPTPTGTQT---PTTTPITTTTTVTPTPTPTGTQTPTTTPI 2752



 Score = 49.3 bits (116), Expect = 2e-05
 Identities = 83/410 (20%), Positives = 127/410 (30%), Gaps = 42/410 (10%)

Query: 258  TGLLKQTHIAPKPAAHLAAPANGSAPSAPAQPPCFHLALPQNSPSPAAGQ-PVTVAQGAP 316
            T +   T + P P          +    P   P         +P+P   Q P T      
Sbjct: 2382 TPITTTTTVTPTPTP--------TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 2433

Query: 317  GSLTHSPPAAGQ---------SHMTLVSSPLPVGQNSLTLQP--------PAPQPVFLSH 359
             ++T +P   G          +  T+  +P P G  + T  P        P P P     
Sbjct: 2434 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 2493

Query: 360  GVPLHQSVNPPVLPLSQPVGPVNKSVGTSVLPINQTVRPGVLPLTQPVGPINRPVGPGVL 419
                  +    V P   P G   ++  T+ +    TV P   P T    P   P+     
Sbjct: 2494 PTTTPITTTTTVTPTPTPTG--TQTPTTTPITTTTTVTPTPTP-TGTQTPTTTPITT-TT 2549

Query: 420  PVSPSVTPGVLQAVSPGVLSVSRAVPSGVLPAGQMTPAGQ--MTPAGVIPGQTATSGVLP 477
             V+P+ TP   Q  +   ++ +  V     P G  TP      T   V P  T T    P
Sbjct: 2550 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 2609

Query: 478  TGQMVQSGVLPVGQTAPSRVLPPGQTAPLRVISA--GQVVPSGLLSPNQT-VSSSAVVPV 534
            T   + +         P+    P  T P+   +       P+G  +P  T ++++  V  
Sbjct: 2610 TTTPITTTTTVTPTPTPTGTQTP-TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 2668

Query: 535  NQGVNSGVLQLSQPVVSGVLPVGQPVRPGVLQLNQT---VGTNILPVNQPVRPGASQNTT 591
                       + P+ +       P   G      T     T + P   P        T 
Sbjct: 2669 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2728

Query: 592  FLTSGSILRQLIPTGKQVNGIPTYTLAPVSVTLPVPPGGLATVAPPQMPI 641
              T+ ++     PTG Q    PT T    + T+   P    T  P   PI
Sbjct: 2729 ITTTTTVTPTPTPTGTQT---PTTTPITTTTTVTPTPTPTGTQTPTTTPI 2775



 Score = 49.3 bits (116), Expect = 2e-05
 Identities = 83/410 (20%), Positives = 127/410 (30%), Gaps = 42/410 (10%)

Query: 258  TGLLKQTHIAPKPAAHLAAPANGSAPSAPAQPPCFHLALPQNSPSPAAGQ-PVTVAQGAP 316
            T +   T + P P          +    P   P         +P+P   Q P T      
Sbjct: 2405 TPITTTTTVTPTPTP--------TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 2456

Query: 317  GSLTHSPPAAGQ---------SHMTLVSSPLPVGQNSLTLQP--------PAPQPVFLSH 359
             ++T +P   G          +  T+  +P P G  + T  P        P P P     
Sbjct: 2457 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 2516

Query: 360  GVPLHQSVNPPVLPLSQPVGPVNKSVGTSVLPINQTVRPGVLPLTQPVGPINRPVGPGVL 419
                  +    V P   P G   ++  T+ +    TV P   P T    P   P+     
Sbjct: 2517 PTTTPITTTTTVTPTPTPTG--TQTPTTTPITTTTTVTPTPTP-TGTQTPTTTPITT-TT 2572

Query: 420  PVSPSVTPGVLQAVSPGVLSVSRAVPSGVLPAGQMTPAGQ--MTPAGVIPGQTATSGVLP 477
             V+P+ TP   Q  +   ++ +  V     P G  TP      T   V P  T T    P
Sbjct: 2573 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 2632

Query: 478  TGQMVQSGVLPVGQTAPSRVLPPGQTAPLRVISA--GQVVPSGLLSPNQT-VSSSAVVPV 534
            T   + +         P+    P  T P+   +       P+G  +P  T ++++  V  
Sbjct: 2633 TTTPITTTTTVTPTPTPTGTQTP-TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 2691

Query: 535  NQGVNSGVLQLSQPVVSGVLPVGQPVRPGVLQLNQT---VGTNILPVNQPVRPGASQNTT 591
                       + P+ +       P   G      T     T + P   P        T 
Sbjct: 2692 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2751

Query: 592  FLTSGSILRQLIPTGKQVNGIPTYTLAPVSVTLPVPPGGLATVAPPQMPI 641
              T+ ++     PTG Q    PT T    + T+   P    T  P   PI
Sbjct: 2752 ITTTTTVTPTPTPTGTQT---PTTTPITTTTTVTPTPTPTGTQTPTTTPI 2798



 Score = 49.3 bits (116), Expect = 2e-05
 Identities = 83/410 (20%), Positives = 127/410 (30%), Gaps = 42/410 (10%)

Query: 258  TGLLKQTHIAPKPAAHLAAPANGSAPSAPAQPPCFHLALPQNSPSPAAGQ-PVTVAQGAP 316
            T +   T + P P          +    P   P         +P+P   Q P T      
Sbjct: 2428 TPITTTTTVTPTPTP--------TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 2479

Query: 317  GSLTHSPPAAGQ---------SHMTLVSSPLPVGQNSLTLQP--------PAPQPVFLSH 359
             ++T +P   G          +  T+  +P P G  + T  P        P P P     
Sbjct: 2480 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 2539

Query: 360  GVPLHQSVNPPVLPLSQPVGPVNKSVGTSVLPINQTVRPGVLPLTQPVGPINRPVGPGVL 419
                  +    V P   P G   ++  T+ +    TV P   P T    P   P+     
Sbjct: 2540 PTTTPITTTTTVTPTPTPTG--TQTPTTTPITTTTTVTPTPTP-TGTQTPTTTPITT-TT 2595

Query: 420  PVSPSVTPGVLQAVSPGVLSVSRAVPSGVLPAGQMTPAGQ--MTPAGVIPGQTATSGVLP 477
             V+P+ TP   Q  +   ++ +  V     P G  TP      T   V P  T T    P
Sbjct: 2596 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 2655

Query: 478  TGQMVQSGVLPVGQTAPSRVLPPGQTAPLRVISA--GQVVPSGLLSPNQT-VSSSAVVPV 534
            T   + +         P+    P  T P+   +       P+G  +P  T ++++  V  
Sbjct: 2656 TTTPITTTTTVTPTPTPTGTQTP-TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 2714

Query: 535  NQGVNSGVLQLSQPVVSGVLPVGQPVRPGVLQLNQT---VGTNILPVNQPVRPGASQNTT 591
                       + P+ +       P   G      T     T + P   P        T 
Sbjct: 2715 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2774

Query: 592  FLTSGSILRQLIPTGKQVNGIPTYTLAPVSVTLPVPPGGLATVAPPQMPI 641
              T+ ++     PTG Q    PT T    + T+   P    T  P   PI
Sbjct: 2775 ITTTTTVTPTPTPTGTQT---PTTTPITTTTTVTPTPTPTGTQTPTTTPI 2821



 Score = 49.3 bits (116), Expect = 2e-05
 Identities = 83/410 (20%), Positives = 127/410 (30%), Gaps = 42/410 (10%)

Query: 258  TGLLKQTHIAPKPAAHLAAPANGSAPSAPAQPPCFHLALPQNSPSPAAGQ-PVTVAQGAP 316
            T +   T + P P          +    P   P         +P+P   Q P T      
Sbjct: 2451 TPITTTTTVTPTPTP--------TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 2502

Query: 317  GSLTHSPPAAGQ---------SHMTLVSSPLPVGQNSLTLQP--------PAPQPVFLSH 359
             ++T +P   G          +  T+  +P P G  + T  P        P P P     
Sbjct: 2503 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 2562

Query: 360  GVPLHQSVNPPVLPLSQPVGPVNKSVGTSVLPINQTVRPGVLPLTQPVGPINRPVGPGVL 419
                  +    V P   P G   ++  T+ +    TV P   P T    P   P+     
Sbjct: 2563 PTTTPITTTTTVTPTPTPTG--TQTPTTTPITTTTTVTPTPTP-TGTQTPTTTPITT-TT 2618

Query: 420  PVSPSVTPGVLQAVSPGVLSVSRAVPSGVLPAGQMTPAGQ--MTPAGVIPGQTATSGVLP 477
             V+P+ TP   Q  +   ++ +  V     P G  TP      T   V P  T T    P
Sbjct: 2619 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 2678

Query: 478  TGQMVQSGVLPVGQTAPSRVLPPGQTAPLRVISA--GQVVPSGLLSPNQT-VSSSAVVPV 534
            T   + +         P+    P  T P+   +       P+G  +P  T ++++  V  
Sbjct: 2679 TTTPITTTTTVTPTPTPTGTQTP-TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 2737

Query: 535  NQGVNSGVLQLSQPVVSGVLPVGQPVRPGVLQLNQT---VGTNILPVNQPVRPGASQNTT 591
                       + P+ +       P   G      T     T + P   P        T 
Sbjct: 2738 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2797

Query: 592  FLTSGSILRQLIPTGKQVNGIPTYTLAPVSVTLPVPPGGLATVAPPQMPI 641
              T+ ++     PTG Q    PT T    + T+   P    T  P   PI
Sbjct: 2798 ITTTTTVTPTPTPTGTQT---PTTTPITTTTTVTPTPTPTGTQTPTTTPI 2844



 Score = 49.3 bits (116), Expect = 2e-05
 Identities = 83/410 (20%), Positives = 127/410 (30%), Gaps = 42/410 (10%)

Query: 258  TGLLKQTHIAPKPAAHLAAPANGSAPSAPAQPPCFHLALPQNSPSPAAGQ-PVTVAQGAP 316
            T +   T + P P          +    P   P         +P+P   Q P T      
Sbjct: 2474 TPITTTTTVTPTPTP--------TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 2525

Query: 317  GSLTHSPPAAGQ---------SHMTLVSSPLPVGQNSLTLQP--------PAPQPVFLSH 359
             ++T +P   G          +  T+  +P P G  + T  P        P P P     
Sbjct: 2526 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 2585

Query: 360  GVPLHQSVNPPVLPLSQPVGPVNKSVGTSVLPINQTVRPGVLPLTQPVGPINRPVGPGVL 419
                  +    V P   P G   ++  T+ +    TV P   P T    P   P+     
Sbjct: 2586 PTTTPITTTTTVTPTPTPTG--TQTPTTTPITTTTTVTPTPTP-TGTQTPTTTPITT-TT 2641

Query: 420  PVSPSVTPGVLQAVSPGVLSVSRAVPSGVLPAGQMTPAGQ--MTPAGVIPGQTATSGVLP 477
             V+P+ TP   Q  +   ++ +  V     P G  TP      T   V P  T T    P
Sbjct: 2642 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 2701

Query: 478  TGQMVQSGVLPVGQTAPSRVLPPGQTAPLRVISA--GQVVPSGLLSPNQT-VSSSAVVPV 534
            T   + +         P+    P  T P+   +       P+G  +P  T ++++  V  
Sbjct: 2702 TTTPITTTTTVTPTPTPTGTQTP-TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 2760

Query: 535  NQGVNSGVLQLSQPVVSGVLPVGQPVRPGVLQLNQT---VGTNILPVNQPVRPGASQNTT 591
                       + P+ +       P   G      T     T + P   P        T 
Sbjct: 2761 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2820

Query: 592  FLTSGSILRQLIPTGKQVNGIPTYTLAPVSVTLPVPPGGLATVAPPQMPI 641
              T+ ++     PTG Q    PT T    + T+   P    T  P   PI
Sbjct: 2821 ITTTTTVTPTPTPTGTQT---PTTTPITTTTTVTPTPTPTGTQTPTTTPI 2867



 Score = 49.3 bits (116), Expect = 2e-05
 Identities = 83/410 (20%), Positives = 127/410 (30%), Gaps = 42/410 (10%)

Query: 258  TGLLKQTHIAPKPAAHLAAPANGSAPSAPAQPPCFHLALPQNSPSPAAGQ-PVTVAQGAP 316
            T +   T + P P          +    P   P         +P+P   Q P T      
Sbjct: 2497 TPITTTTTVTPTPTP--------TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 2548

Query: 317  GSLTHSPPAAGQ---------SHMTLVSSPLPVGQNSLTLQP--------PAPQPVFLSH 359
             ++T +P   G          +  T+  +P P G  + T  P        P P P     
Sbjct: 2549 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 2608

Query: 360  GVPLHQSVNPPVLPLSQPVGPVNKSVGTSVLPINQTVRPGVLPLTQPVGPINRPVGPGVL 419
                  +    V P   P G   ++  T+ +    TV P   P T    P   P+     
Sbjct: 2609 PTTTPITTTTTVTPTPTPTG--TQTPTTTPITTTTTVTPTPTP-TGTQTPTTTPITT-TT 2664

Query: 420  PVSPSVTPGVLQAVSPGVLSVSRAVPSGVLPAGQMTPAGQ--MTPAGVIPGQTATSGVLP 477
             V+P+ TP   Q  +   ++ +  V     P G  TP      T   V P  T T    P
Sbjct: 2665 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 2724

Query: 478  TGQMVQSGVLPVGQTAPSRVLPPGQTAPLRVISA--GQVVPSGLLSPNQT-VSSSAVVPV 534
            T   + +         P+    P  T P+   +       P+G  +P  T ++++  V  
Sbjct: 2725 TTTPITTTTTVTPTPTPTGTQTP-TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 2783

Query: 535  NQGVNSGVLQLSQPVVSGVLPVGQPVRPGVLQLNQT---VGTNILPVNQPVRPGASQNTT 591
                       + P+ +       P   G      T     T + P   P        T 
Sbjct: 2784 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2843

Query: 592  FLTSGSILRQLIPTGKQVNGIPTYTLAPVSVTLPVPPGGLATVAPPQMPI 641
              T+ ++     PTG Q    PT T    + T+   P    T  P   PI
Sbjct: 2844 ITTTTTVTPTPTPTGTQT---PTTTPITTTTTVTPTPTPTGTQTPTTTPI 2890



 Score = 49.3 bits (116), Expect = 2e-05
 Identities = 83/410 (20%), Positives = 127/410 (30%), Gaps = 42/410 (10%)

Query: 258  TGLLKQTHIAPKPAAHLAAPANGSAPSAPAQPPCFHLALPQNSPSPAAGQ-PVTVAQGAP 316
            T +   T + P P          +    P   P         +P+P   Q P T      
Sbjct: 2520 TPITTTTTVTPTPTP--------TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 2571

Query: 317  GSLTHSPPAAGQ---------SHMTLVSSPLPVGQNSLTLQP--------PAPQPVFLSH 359
             ++T +P   G          +  T+  +P P G  + T  P        P P P     
Sbjct: 2572 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 2631

Query: 360  GVPLHQSVNPPVLPLSQPVGPVNKSVGTSVLPINQTVRPGVLPLTQPVGPINRPVGPGVL 419
                  +    V P   P G   ++  T+ +    TV P   P T    P   P+     
Sbjct: 2632 PTTTPITTTTTVTPTPTPTG--TQTPTTTPITTTTTVTPTPTP-TGTQTPTTTPITT-TT 2687

Query: 420  PVSPSVTPGVLQAVSPGVLSVSRAVPSGVLPAGQMTPAGQ--MTPAGVIPGQTATSGVLP 477
             V+P+ TP   Q  +   ++ +  V     P G  TP      T   V P  T T    P
Sbjct: 2688 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 2747

Query: 478  TGQMVQSGVLPVGQTAPSRVLPPGQTAPLRVISA--GQVVPSGLLSPNQT-VSSSAVVPV 534
            T   + +         P+    P  T P+   +       P+G  +P  T ++++  V  
Sbjct: 2748 TTTPITTTTTVTPTPTPTGTQTP-TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 2806

Query: 535  NQGVNSGVLQLSQPVVSGVLPVGQPVRPGVLQLNQT---VGTNILPVNQPVRPGASQNTT 591
                       + P+ +       P   G      T     T + P   P        T 
Sbjct: 2807 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2866

Query: 592  FLTSGSILRQLIPTGKQVNGIPTYTLAPVSVTLPVPPGGLATVAPPQMPI 641
              T+ ++     PTG Q    PT T    + T+   P    T  P   PI
Sbjct: 2867 ITTTTTVTPTPTPTGTQT---PTTTPITTTTTVTPTPTPTGTQTPTTTPI 2913



 Score = 49.3 bits (116), Expect = 2e-05
 Identities = 83/410 (20%), Positives = 127/410 (30%), Gaps = 42/410 (10%)

Query: 258  TGLLKQTHIAPKPAAHLAAPANGSAPSAPAQPPCFHLALPQNSPSPAAGQ-PVTVAQGAP 316
            T +   T + P P          +    P   P         +P+P   Q P T      
Sbjct: 2543 TPITTTTTVTPTPTP--------TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 2594

Query: 317  GSLTHSPPAAGQ---------SHMTLVSSPLPVGQNSLTLQP--------PAPQPVFLSH 359
             ++T +P   G          +  T+  +P P G  + T  P        P P P     
Sbjct: 2595 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 2654

Query: 360  GVPLHQSVNPPVLPLSQPVGPVNKSVGTSVLPINQTVRPGVLPLTQPVGPINRPVGPGVL 419
                  +    V P   P G   ++  T+ +    TV P   P T    P   P+     
Sbjct: 2655 PTTTPITTTTTVTPTPTPTG--TQTPTTTPITTTTTVTPTPTP-TGTQTPTTTPITT-TT 2710

Query: 420  PVSPSVTPGVLQAVSPGVLSVSRAVPSGVLPAGQMTPAGQ--MTPAGVIPGQTATSGVLP 477
             V+P+ TP   Q  +   ++ +  V     P G  TP      T   V P  T T    P
Sbjct: 2711 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 2770

Query: 478  TGQMVQSGVLPVGQTAPSRVLPPGQTAPLRVISA--GQVVPSGLLSPNQT-VSSSAVVPV 534
            T   + +         P+    P  T P+   +       P+G  +P  T ++++  V  
Sbjct: 2771 TTTPITTTTTVTPTPTPTGTQTP-TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 2829

Query: 535  NQGVNSGVLQLSQPVVSGVLPVGQPVRPGVLQLNQT---VGTNILPVNQPVRPGASQNTT 591
                       + P+ +       P   G      T     T + P   P        T 
Sbjct: 2830 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2889

Query: 592  FLTSGSILRQLIPTGKQVNGIPTYTLAPVSVTLPVPPGGLATVAPPQMPI 641
              T+ ++     PTG Q    PT T    + T+   P    T  P   PI
Sbjct: 2890 ITTTTTVTPTPTPTGTQT---PTTTPITTTTTVTPTPTPTGTQTPTTTPI 2936



 Score = 49.3 bits (116), Expect = 2e-05
 Identities = 83/410 (20%), Positives = 127/410 (30%), Gaps = 42/410 (10%)

Query: 258  TGLLKQTHIAPKPAAHLAAPANGSAPSAPAQPPCFHLALPQNSPSPAAGQ-PVTVAQGAP 316
            T +   T + P P          +    P   P         +P+P   Q P T      
Sbjct: 2566 TPITTTTTVTPTPTP--------TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 2617

Query: 317  GSLTHSPPAAGQ---------SHMTLVSSPLPVGQNSLTLQP--------PAPQPVFLSH 359
             ++T +P   G          +  T+  +P P G  + T  P        P P P     
Sbjct: 2618 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 2677

Query: 360  GVPLHQSVNPPVLPLSQPVGPVNKSVGTSVLPINQTVRPGVLPLTQPVGPINRPVGPGVL 419
                  +    V P   P G   ++  T+ +    TV P   P T    P   P+     
Sbjct: 2678 PTTTPITTTTTVTPTPTPTG--TQTPTTTPITTTTTVTPTPTP-TGTQTPTTTPITT-TT 2733

Query: 420  PVSPSVTPGVLQAVSPGVLSVSRAVPSGVLPAGQMTPAGQ--MTPAGVIPGQTATSGVLP 477
             V+P+ TP   Q  +   ++ +  V     P G  TP      T   V P  T T    P
Sbjct: 2734 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 2793

Query: 478  TGQMVQSGVLPVGQTAPSRVLPPGQTAPLRVISA--GQVVPSGLLSPNQT-VSSSAVVPV 534
            T   + +         P+    P  T P+   +       P+G  +P  T ++++  V  
Sbjct: 2794 TTTPITTTTTVTPTPTPTGTQTP-TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 2852

Query: 535  NQGVNSGVLQLSQPVVSGVLPVGQPVRPGVLQLNQT---VGTNILPVNQPVRPGASQNTT 591
                       + P+ +       P   G      T     T + P   P        T 
Sbjct: 2853 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2912

Query: 592  FLTSGSILRQLIPTGKQVNGIPTYTLAPVSVTLPVPPGGLATVAPPQMPI 641
              T+ ++     PTG Q    PT T    + T+   P    T  P   PI
Sbjct: 2913 ITTTTTVTPTPTPTGTQT---PTTTPITTTTTVTPTPTPTGTQTPTTTPI 2959



 Score = 49.3 bits (116), Expect = 2e-05
 Identities = 83/410 (20%), Positives = 127/410 (30%), Gaps = 42/410 (10%)

Query: 258  TGLLKQTHIAPKPAAHLAAPANGSAPSAPAQPPCFHLALPQNSPSPAAGQ-PVTVAQGAP 316
            T +   T + P P          +    P   P         +P+P   Q P T      
Sbjct: 2589 TPITTTTTVTPTPTP--------TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 2640

Query: 317  GSLTHSPPAAGQ---------SHMTLVSSPLPVGQNSLTLQP--------PAPQPVFLSH 359
             ++T +P   G          +  T+  +P P G  + T  P        P P P     
Sbjct: 2641 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 2700

Query: 360  GVPLHQSVNPPVLPLSQPVGPVNKSVGTSVLPINQTVRPGVLPLTQPVGPINRPVGPGVL 419
                  +    V P   P G   ++  T+ +    TV P   P T    P   P+     
Sbjct: 2701 PTTTPITTTTTVTPTPTPTG--TQTPTTTPITTTTTVTPTPTP-TGTQTPTTTPITT-TT 2756

Query: 420  PVSPSVTPGVLQAVSPGVLSVSRAVPSGVLPAGQMTPAGQ--MTPAGVIPGQTATSGVLP 477
             V+P+ TP   Q  +   ++ +  V     P G  TP      T   V P  T T    P
Sbjct: 2757 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 2816

Query: 478  TGQMVQSGVLPVGQTAPSRVLPPGQTAPLRVISA--GQVVPSGLLSPNQT-VSSSAVVPV 534
            T   + +         P+    P  T P+   +       P+G  +P  T ++++  V  
Sbjct: 2817 TTTPITTTTTVTPTPTPTGTQTP-TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 2875

Query: 535  NQGVNSGVLQLSQPVVSGVLPVGQPVRPGVLQLNQT---VGTNILPVNQPVRPGASQNTT 591
                       + P+ +       P   G      T     T + P   P        T 
Sbjct: 2876 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2935

Query: 592  FLTSGSILRQLIPTGKQVNGIPTYTLAPVSVTLPVPPGGLATVAPPQMPI 641
              T+ ++     PTG Q    PT T    + T+   P    T  P   PI
Sbjct: 2936 ITTTTTVTPTPTPTGTQT---PTTTPITTTTTVTPTPTPTGTQTPTTTPI 2982



 Score = 49.3 bits (116), Expect = 2e-05
 Identities = 83/410 (20%), Positives = 127/410 (30%), Gaps = 42/410 (10%)

Query: 258  TGLLKQTHIAPKPAAHLAAPANGSAPSAPAQPPCFHLALPQNSPSPAAGQ-PVTVAQGAP 316
            T +   T + P P          +    P   P         +P+P   Q P T      
Sbjct: 2612 TPITTTTTVTPTPTP--------TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 2663

Query: 317  GSLTHSPPAAGQ---------SHMTLVSSPLPVGQNSLTLQP--------PAPQPVFLSH 359
             ++T +P   G          +  T+  +P P G  + T  P        P P P     
Sbjct: 2664 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 2723

Query: 360  GVPLHQSVNPPVLPLSQPVGPVNKSVGTSVLPINQTVRPGVLPLTQPVGPINRPVGPGVL 419
                  +    V P   P G   ++  T+ +    TV P   P T    P   P+     
Sbjct: 2724 PTTTPITTTTTVTPTPTPTG--TQTPTTTPITTTTTVTPTPTP-TGTQTPTTTPITT-TT 2779

Query: 420  PVSPSVTPGVLQAVSPGVLSVSRAVPSGVLPAGQMTPAGQ--MTPAGVIPGQTATSGVLP 477
             V+P+ TP   Q  +   ++ +  V     P G  TP      T   V P  T T    P
Sbjct: 2780 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 2839

Query: 478  TGQMVQSGVLPVGQTAPSRVLPPGQTAPLRVISA--GQVVPSGLLSPNQT-VSSSAVVPV 534
            T   + +         P+    P  T P+   +       P+G  +P  T ++++  V  
Sbjct: 2840 TTTPITTTTTVTPTPTPTGTQTP-TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 2898

Query: 535  NQGVNSGVLQLSQPVVSGVLPVGQPVRPGVLQLNQT---VGTNILPVNQPVRPGASQNTT 591
                       + P+ +       P   G      T     T + P   P        T 
Sbjct: 2899 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2958

Query: 592  FLTSGSILRQLIPTGKQVNGIPTYTLAPVSVTLPVPPGGLATVAPPQMPI 641
              T+ ++     PTG Q    PT T    + T+   P    T  P   PI
Sbjct: 2959 ITTTTTVTPTPTPTGTQT---PTTTPITTTTTVTPTPTPTGTQTPTTTPI 3005



 Score = 49.3 bits (116), Expect = 2e-05
 Identities = 83/410 (20%), Positives = 127/410 (30%), Gaps = 42/410 (10%)

Query: 258  TGLLKQTHIAPKPAAHLAAPANGSAPSAPAQPPCFHLALPQNSPSPAAGQ-PVTVAQGAP 316
            T +   T + P P          +    P   P         +P+P   Q P T      
Sbjct: 2635 TPITTTTTVTPTPTP--------TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 2686

Query: 317  GSLTHSPPAAGQ---------SHMTLVSSPLPVGQNSLTLQP--------PAPQPVFLSH 359
             ++T +P   G          +  T+  +P P G  + T  P        P P P     
Sbjct: 2687 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 2746

Query: 360  GVPLHQSVNPPVLPLSQPVGPVNKSVGTSVLPINQTVRPGVLPLTQPVGPINRPVGPGVL 419
                  +    V P   P G   ++  T+ +    TV P   P T    P   P+     
Sbjct: 2747 PTTTPITTTTTVTPTPTPTG--TQTPTTTPITTTTTVTPTPTP-TGTQTPTTTPITT-TT 2802

Query: 420  PVSPSVTPGVLQAVSPGVLSVSRAVPSGVLPAGQMTPAGQ--MTPAGVIPGQTATSGVLP 477
             V+P+ TP   Q  +   ++ +  V     P G  TP      T   V P  T T    P
Sbjct: 2803 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 2862

Query: 478  TGQMVQSGVLPVGQTAPSRVLPPGQTAPLRVISA--GQVVPSGLLSPNQT-VSSSAVVPV 534
            T   + +         P+    P  T P+   +       P+G  +P  T ++++  V  
Sbjct: 2863 TTTPITTTTTVTPTPTPTGTQTP-TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 2921

Query: 535  NQGVNSGVLQLSQPVVSGVLPVGQPVRPGVLQLNQT---VGTNILPVNQPVRPGASQNTT 591
                       + P+ +       P   G      T     T + P   P        T 
Sbjct: 2922 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2981

Query: 592  FLTSGSILRQLIPTGKQVNGIPTYTLAPVSVTLPVPPGGLATVAPPQMPI 641
              T+ ++     PTG Q    PT T    + T+   P    T  P   PI
Sbjct: 2982 ITTTTTVTPTPTPTGTQT---PTTTPITTTTTVTPTPTPTGTQTPTTTPI 3028



 Score = 49.3 bits (116), Expect = 2e-05
 Identities = 83/410 (20%), Positives = 127/410 (30%), Gaps = 42/410 (10%)

Query: 258  TGLLKQTHIAPKPAAHLAAPANGSAPSAPAQPPCFHLALPQNSPSPAAGQ-PVTVAQGAP 316
            T +   T + P P          +    P   P         +P+P   Q P T      
Sbjct: 2658 TPITTTTTVTPTPTP--------TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 2709

Query: 317  GSLTHSPPAAGQ---------SHMTLVSSPLPVGQNSLTLQP--------PAPQPVFLSH 359
             ++T +P   G          +  T+  +P P G  + T  P        P P P     
Sbjct: 2710 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 2769

Query: 360  GVPLHQSVNPPVLPLSQPVGPVNKSVGTSVLPINQTVRPGVLPLTQPVGPINRPVGPGVL 419
                  +    V P   P G   ++  T+ +    TV P   P T    P   P+     
Sbjct: 2770 PTTTPITTTTTVTPTPTPTG--TQTPTTTPITTTTTVTPTPTP-TGTQTPTTTPITT-TT 2825

Query: 420  PVSPSVTPGVLQAVSPGVLSVSRAVPSGVLPAGQMTPAGQ--MTPAGVIPGQTATSGVLP 477
             V+P+ TP   Q  +   ++ +  V     P G  TP      T   V P  T T    P
Sbjct: 2826 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 2885

Query: 478  TGQMVQSGVLPVGQTAPSRVLPPGQTAPLRVISA--GQVVPSGLLSPNQT-VSSSAVVPV 534
            T   + +         P+    P  T P+   +       P+G  +P  T ++++  V  
Sbjct: 2886 TTTPITTTTTVTPTPTPTGTQTP-TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 2944

Query: 535  NQGVNSGVLQLSQPVVSGVLPVGQPVRPGVLQLNQT---VGTNILPVNQPVRPGASQNTT 591
                       + P+ +       P   G      T     T + P   P        T 
Sbjct: 2945 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3004

Query: 592  FLTSGSILRQLIPTGKQVNGIPTYTLAPVSVTLPVPPGGLATVAPPQMPI 641
              T+ ++     PTG Q    PT T    + T+   P    T  P   PI
Sbjct: 3005 ITTTTTVTPTPTPTGTQT---PTTTPITTTTTVTPTPTPTGTQTPTTTPI 3051



 Score = 49.3 bits (116), Expect = 2e-05
 Identities = 83/410 (20%), Positives = 127/410 (30%), Gaps = 42/410 (10%)

Query: 258  TGLLKQTHIAPKPAAHLAAPANGSAPSAPAQPPCFHLALPQNSPSPAAGQ-PVTVAQGAP 316
            T +   T + P P          +    P   P         +P+P   Q P T      
Sbjct: 2681 TPITTTTTVTPTPTP--------TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 2732

Query: 317  GSLTHSPPAAGQ---------SHMTLVSSPLPVGQNSLTLQP--------PAPQPVFLSH 359
             ++T +P   G          +  T+  +P P G  + T  P        P P P     
Sbjct: 2733 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 2792

Query: 360  GVPLHQSVNPPVLPLSQPVGPVNKSVGTSVLPINQTVRPGVLPLTQPVGPINRPVGPGVL 419
                  +    V P   P G   ++  T+ +    TV P   P T    P   P+     
Sbjct: 2793 PTTTPITTTTTVTPTPTPTG--TQTPTTTPITTTTTVTPTPTP-TGTQTPTTTPITT-TT 2848

Query: 420  PVSPSVTPGVLQAVSPGVLSVSRAVPSGVLPAGQMTPAGQ--MTPAGVIPGQTATSGVLP 477
             V+P+ TP   Q  +   ++ +  V     P G  TP      T   V P  T T    P
Sbjct: 2849 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 2908

Query: 478  TGQMVQSGVLPVGQTAPSRVLPPGQTAPLRVISA--GQVVPSGLLSPNQT-VSSSAVVPV 534
            T   + +         P+    P  T P+   +       P+G  +P  T ++++  V  
Sbjct: 2909 TTTPITTTTTVTPTPTPTGTQTP-TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 2967

Query: 535  NQGVNSGVLQLSQPVVSGVLPVGQPVRPGVLQLNQT---VGTNILPVNQPVRPGASQNTT 591
                       + P+ +       P   G      T     T + P   P        T 
Sbjct: 2968 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3027

Query: 592  FLTSGSILRQLIPTGKQVNGIPTYTLAPVSVTLPVPPGGLATVAPPQMPI 641
              T+ ++     PTG Q    PT T    + T+   P    T  P   PI
Sbjct: 3028 ITTTTTVTPTPTPTGTQT---PTTTPITTTTTVTPTPTPTGTQTPTTTPI 3074



 Score = 49.3 bits (116), Expect = 2e-05
 Identities = 83/410 (20%), Positives = 127/410 (30%), Gaps = 42/410 (10%)

Query: 258  TGLLKQTHIAPKPAAHLAAPANGSAPSAPAQPPCFHLALPQNSPSPAAGQ-PVTVAQGAP 316
            T +   T + P P          +    P   P         +P+P   Q P T      
Sbjct: 2704 TPITTTTTVTPTPTP--------TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 2755

Query: 317  GSLTHSPPAAGQ---------SHMTLVSSPLPVGQNSLTLQP--------PAPQPVFLSH 359
             ++T +P   G          +  T+  +P P G  + T  P        P P P     
Sbjct: 2756 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 2815

Query: 360  GVPLHQSVNPPVLPLSQPVGPVNKSVGTSVLPINQTVRPGVLPLTQPVGPINRPVGPGVL 419
                  +    V P   P G   ++  T+ +    TV P   P T    P   P+     
Sbjct: 2816 PTTTPITTTTTVTPTPTPTG--TQTPTTTPITTTTTVTPTPTP-TGTQTPTTTPITT-TT 2871

Query: 420  PVSPSVTPGVLQAVSPGVLSVSRAVPSGVLPAGQMTPAGQ--MTPAGVIPGQTATSGVLP 477
             V+P+ TP   Q  +   ++ +  V     P G  TP      T   V P  T T    P
Sbjct: 2872 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 2931

Query: 478  TGQMVQSGVLPVGQTAPSRVLPPGQTAPLRVISA--GQVVPSGLLSPNQT-VSSSAVVPV 534
            T   + +         P+    P  T P+   +       P+G  +P  T ++++  V  
Sbjct: 2932 TTTPITTTTTVTPTPTPTGTQTP-TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 2990

Query: 535  NQGVNSGVLQLSQPVVSGVLPVGQPVRPGVLQLNQT---VGTNILPVNQPVRPGASQNTT 591
                       + P+ +       P   G      T     T + P   P        T 
Sbjct: 2991 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3050

Query: 592  FLTSGSILRQLIPTGKQVNGIPTYTLAPVSVTLPVPPGGLATVAPPQMPI 641
              T+ ++     PTG Q    PT T    + T+   P    T  P   PI
Sbjct: 3051 ITTTTTVTPTPTPTGTQT---PTTTPITTTTTVTPTPTPTGTQTPTTTPI 3097



 Score = 49.3 bits (116), Expect = 2e-05
 Identities = 83/410 (20%), Positives = 127/410 (30%), Gaps = 42/410 (10%)

Query: 258  TGLLKQTHIAPKPAAHLAAPANGSAPSAPAQPPCFHLALPQNSPSPAAGQ-PVTVAQGAP 316
            T +   T + P P          +    P   P         +P+P   Q P T      
Sbjct: 2727 TPITTTTTVTPTPTP--------TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 2778

Query: 317  GSLTHSPPAAGQ---------SHMTLVSSPLPVGQNSLTLQP--------PAPQPVFLSH 359
             ++T +P   G          +  T+  +P P G  + T  P        P P P     
Sbjct: 2779 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 2838

Query: 360  GVPLHQSVNPPVLPLSQPVGPVNKSVGTSVLPINQTVRPGVLPLTQPVGPINRPVGPGVL 419
                  +    V P   P G   ++  T+ +    TV P   P T    P   P+     
Sbjct: 2839 PTTTPITTTTTVTPTPTPTG--TQTPTTTPITTTTTVTPTPTP-TGTQTPTTTPITT-TT 2894

Query: 420  PVSPSVTPGVLQAVSPGVLSVSRAVPSGVLPAGQMTPAGQ--MTPAGVIPGQTATSGVLP 477
             V+P+ TP   Q  +   ++ +  V     P G  TP      T   V P  T T    P
Sbjct: 2895 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 2954

Query: 478  TGQMVQSGVLPVGQTAPSRVLPPGQTAPLRVISA--GQVVPSGLLSPNQT-VSSSAVVPV 534
            T   + +         P+    P  T P+   +       P+G  +P  T ++++  V  
Sbjct: 2955 TTTPITTTTTVTPTPTPTGTQTP-TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3013

Query: 535  NQGVNSGVLQLSQPVVSGVLPVGQPVRPGVLQLNQT---VGTNILPVNQPVRPGASQNTT 591
                       + P+ +       P   G      T     T + P   P        T 
Sbjct: 3014 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3073

Query: 592  FLTSGSILRQLIPTGKQVNGIPTYTLAPVSVTLPVPPGGLATVAPPQMPI 641
              T+ ++     PTG Q    PT T    + T+   P    T  P   PI
Sbjct: 3074 ITTTTTVTPTPTPTGTQT---PTTTPITTTTTVTPTPTPTGTQTPTTTPI 3120



 Score = 49.3 bits (116), Expect = 2e-05
 Identities = 83/410 (20%), Positives = 127/410 (30%), Gaps = 42/410 (10%)

Query: 258  TGLLKQTHIAPKPAAHLAAPANGSAPSAPAQPPCFHLALPQNSPSPAAGQ-PVTVAQGAP 316
            T +   T + P P          +    P   P         +P+P   Q P T      
Sbjct: 2750 TPITTTTTVTPTPTP--------TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 2801

Query: 317  GSLTHSPPAAGQ---------SHMTLVSSPLPVGQNSLTLQP--------PAPQPVFLSH 359
             ++T +P   G          +  T+  +P P G  + T  P        P P P     
Sbjct: 2802 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 2861

Query: 360  GVPLHQSVNPPVLPLSQPVGPVNKSVGTSVLPINQTVRPGVLPLTQPVGPINRPVGPGVL 419
                  +    V P   P G   ++  T+ +    TV P   P T    P   P+     
Sbjct: 2862 PTTTPITTTTTVTPTPTPTG--TQTPTTTPITTTTTVTPTPTP-TGTQTPTTTPITT-TT 2917

Query: 420  PVSPSVTPGVLQAVSPGVLSVSRAVPSGVLPAGQMTPAGQ--MTPAGVIPGQTATSGVLP 477
             V+P+ TP   Q  +   ++ +  V     P G  TP      T   V P  T T    P
Sbjct: 2918 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 2977

Query: 478  TGQMVQSGVLPVGQTAPSRVLPPGQTAPLRVISA--GQVVPSGLLSPNQT-VSSSAVVPV 534
            T   + +         P+    P  T P+   +       P+G  +P  T ++++  V  
Sbjct: 2978 TTTPITTTTTVTPTPTPTGTQTP-TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3036

Query: 535  NQGVNSGVLQLSQPVVSGVLPVGQPVRPGVLQLNQT---VGTNILPVNQPVRPGASQNTT 591
                       + P+ +       P   G      T     T + P   P        T 
Sbjct: 3037 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3096

Query: 592  FLTSGSILRQLIPTGKQVNGIPTYTLAPVSVTLPVPPGGLATVAPPQMPI 641
              T+ ++     PTG Q    PT T    + T+   P    T  P   PI
Sbjct: 3097 ITTTTTVTPTPTPTGTQT---PTTTPITTTTTVTPTPTPTGTQTPTTTPI 3143



 Score = 49.3 bits (116), Expect = 2e-05
 Identities = 83/410 (20%), Positives = 127/410 (30%), Gaps = 42/410 (10%)

Query: 258  TGLLKQTHIAPKPAAHLAAPANGSAPSAPAQPPCFHLALPQNSPSPAAGQ-PVTVAQGAP 316
            T +   T + P P          +    P   P         +P+P   Q P T      
Sbjct: 2773 TPITTTTTVTPTPTP--------TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 2824

Query: 317  GSLTHSPPAAGQ---------SHMTLVSSPLPVGQNSLTLQP--------PAPQPVFLSH 359
             ++T +P   G          +  T+  +P P G  + T  P        P P P     
Sbjct: 2825 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 2884

Query: 360  GVPLHQSVNPPVLPLSQPVGPVNKSVGTSVLPINQTVRPGVLPLTQPVGPINRPVGPGVL 419
                  +    V P   P G   ++  T+ +    TV P   P T    P   P+     
Sbjct: 2885 PTTTPITTTTTVTPTPTPTG--TQTPTTTPITTTTTVTPTPTP-TGTQTPTTTPITT-TT 2940

Query: 420  PVSPSVTPGVLQAVSPGVLSVSRAVPSGVLPAGQMTPAGQ--MTPAGVIPGQTATSGVLP 477
             V+P+ TP   Q  +   ++ +  V     P G  TP      T   V P  T T    P
Sbjct: 2941 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 3000

Query: 478  TGQMVQSGVLPVGQTAPSRVLPPGQTAPLRVISA--GQVVPSGLLSPNQT-VSSSAVVPV 534
            T   + +         P+    P  T P+   +       P+G  +P  T ++++  V  
Sbjct: 3001 TTTPITTTTTVTPTPTPTGTQTP-TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3059

Query: 535  NQGVNSGVLQLSQPVVSGVLPVGQPVRPGVLQLNQT---VGTNILPVNQPVRPGASQNTT 591
                       + P+ +       P   G      T     T + P   P        T 
Sbjct: 3060 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3119

Query: 592  FLTSGSILRQLIPTGKQVNGIPTYTLAPVSVTLPVPPGGLATVAPPQMPI 641
              T+ ++     PTG Q    PT T    + T+   P    T  P   PI
Sbjct: 3120 ITTTTTVTPTPTPTGTQT---PTTTPITTTTTVTPTPTPTGTQTPTTTPI 3166



 Score = 49.3 bits (116), Expect = 2e-05
 Identities = 83/410 (20%), Positives = 127/410 (30%), Gaps = 42/410 (10%)

Query: 258  TGLLKQTHIAPKPAAHLAAPANGSAPSAPAQPPCFHLALPQNSPSPAAGQ-PVTVAQGAP 316
            T +   T + P P          +    P   P         +P+P   Q P T      
Sbjct: 2796 TPITTTTTVTPTPTP--------TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 2847

Query: 317  GSLTHSPPAAGQ---------SHMTLVSSPLPVGQNSLTLQP--------PAPQPVFLSH 359
             ++T +P   G          +  T+  +P P G  + T  P        P P P     
Sbjct: 2848 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 2907

Query: 360  GVPLHQSVNPPVLPLSQPVGPVNKSVGTSVLPINQTVRPGVLPLTQPVGPINRPVGPGVL 419
                  +    V P   P G   ++  T+ +    TV P   P T    P   P+     
Sbjct: 2908 PTTTPITTTTTVTPTPTPTG--TQTPTTTPITTTTTVTPTPTP-TGTQTPTTTPITT-TT 2963

Query: 420  PVSPSVTPGVLQAVSPGVLSVSRAVPSGVLPAGQMTPAGQ--MTPAGVIPGQTATSGVLP 477
             V+P+ TP   Q  +   ++ +  V     P G  TP      T   V P  T T    P
Sbjct: 2964 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 3023

Query: 478  TGQMVQSGVLPVGQTAPSRVLPPGQTAPLRVISA--GQVVPSGLLSPNQT-VSSSAVVPV 534
            T   + +         P+    P  T P+   +       P+G  +P  T ++++  V  
Sbjct: 3024 TTTPITTTTTVTPTPTPTGTQTP-TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3082

Query: 535  NQGVNSGVLQLSQPVVSGVLPVGQPVRPGVLQLNQT---VGTNILPVNQPVRPGASQNTT 591
                       + P+ +       P   G      T     T + P   P        T 
Sbjct: 3083 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3142

Query: 592  FLTSGSILRQLIPTGKQVNGIPTYTLAPVSVTLPVPPGGLATVAPPQMPI 641
              T+ ++     PTG Q    PT T    + T+   P    T  P   PI
Sbjct: 3143 ITTTTTVTPTPTPTGTQT---PTTTPITTTTTVTPTPTPTGTQTPTTTPI 3189



 Score = 49.3 bits (116), Expect = 2e-05
 Identities = 83/410 (20%), Positives = 127/410 (30%), Gaps = 42/410 (10%)

Query: 258  TGLLKQTHIAPKPAAHLAAPANGSAPSAPAQPPCFHLALPQNSPSPAAGQ-PVTVAQGAP 316
            T +   T + P P          +    P   P         +P+P   Q P T      
Sbjct: 2819 TPITTTTTVTPTPTP--------TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 2870

Query: 317  GSLTHSPPAAGQ---------SHMTLVSSPLPVGQNSLTLQP--------PAPQPVFLSH 359
             ++T +P   G          +  T+  +P P G  + T  P        P P P     
Sbjct: 2871 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 2930

Query: 360  GVPLHQSVNPPVLPLSQPVGPVNKSVGTSVLPINQTVRPGVLPLTQPVGPINRPVGPGVL 419
                  +    V P   P G   ++  T+ +    TV P   P T    P   P+     
Sbjct: 2931 PTTTPITTTTTVTPTPTPTG--TQTPTTTPITTTTTVTPTPTP-TGTQTPTTTPITT-TT 2986

Query: 420  PVSPSVTPGVLQAVSPGVLSVSRAVPSGVLPAGQMTPAGQ--MTPAGVIPGQTATSGVLP 477
             V+P+ TP   Q  +   ++ +  V     P G  TP      T   V P  T T    P
Sbjct: 2987 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 3046

Query: 478  TGQMVQSGVLPVGQTAPSRVLPPGQTAPLRVISA--GQVVPSGLLSPNQT-VSSSAVVPV 534
            T   + +         P+    P  T P+   +       P+G  +P  T ++++  V  
Sbjct: 3047 TTTPITTTTTVTPTPTPTGTQTP-TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3105

Query: 535  NQGVNSGVLQLSQPVVSGVLPVGQPVRPGVLQLNQT---VGTNILPVNQPVRPGASQNTT 591
                       + P+ +       P   G      T     T + P   P        T 
Sbjct: 3106 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3165

Query: 592  FLTSGSILRQLIPTGKQVNGIPTYTLAPVSVTLPVPPGGLATVAPPQMPI 641
              T+ ++     PTG Q    PT T    + T+   P    T  P   PI
Sbjct: 3166 ITTTTTVTPTPTPTGTQT---PTTTPITTTTTVTPTPTPTGTQTPTTTPI 3212



 Score = 49.3 bits (116), Expect = 2e-05
 Identities = 83/410 (20%), Positives = 127/410 (30%), Gaps = 42/410 (10%)

Query: 258  TGLLKQTHIAPKPAAHLAAPANGSAPSAPAQPPCFHLALPQNSPSPAAGQ-PVTVAQGAP 316
            T +   T + P P          +    P   P         +P+P   Q P T      
Sbjct: 2842 TPITTTTTVTPTPTP--------TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 2893

Query: 317  GSLTHSPPAAGQ---------SHMTLVSSPLPVGQNSLTLQP--------PAPQPVFLSH 359
             ++T +P   G          +  T+  +P P G  + T  P        P P P     
Sbjct: 2894 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 2953

Query: 360  GVPLHQSVNPPVLPLSQPVGPVNKSVGTSVLPINQTVRPGVLPLTQPVGPINRPVGPGVL 419
                  +    V P   P G   ++  T+ +    TV P   P T    P   P+     
Sbjct: 2954 PTTTPITTTTTVTPTPTPTG--TQTPTTTPITTTTTVTPTPTP-TGTQTPTTTPITT-TT 3009

Query: 420  PVSPSVTPGVLQAVSPGVLSVSRAVPSGVLPAGQMTPAGQ--MTPAGVIPGQTATSGVLP 477
             V+P+ TP   Q  +   ++ +  V     P G  TP      T   V P  T T    P
Sbjct: 3010 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 3069

Query: 478  TGQMVQSGVLPVGQTAPSRVLPPGQTAPLRVISA--GQVVPSGLLSPNQT-VSSSAVVPV 534
            T   + +         P+    P  T P+   +       P+G  +P  T ++++  V  
Sbjct: 3070 TTTPITTTTTVTPTPTPTGTQTP-TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3128

Query: 535  NQGVNSGVLQLSQPVVSGVLPVGQPVRPGVLQLNQT---VGTNILPVNQPVRPGASQNTT 591
                       + P+ +       P   G      T     T + P   P        T 
Sbjct: 3129 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3188

Query: 592  FLTSGSILRQLIPTGKQVNGIPTYTLAPVSVTLPVPPGGLATVAPPQMPI 641
              T+ ++     PTG Q    PT T    + T+   P    T  P   PI
Sbjct: 3189 ITTTTTVTPTPTPTGTQT---PTTTPITTTTTVTPTPTPTGTQTPTTTPI 3235



 Score = 49.3 bits (116), Expect = 2e-05
 Identities = 83/410 (20%), Positives = 127/410 (30%), Gaps = 42/410 (10%)

Query: 258  TGLLKQTHIAPKPAAHLAAPANGSAPSAPAQPPCFHLALPQNSPSPAAGQ-PVTVAQGAP 316
            T +   T + P P          +    P   P         +P+P   Q P T      
Sbjct: 2865 TPITTTTTVTPTPTP--------TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 2916

Query: 317  GSLTHSPPAAGQ---------SHMTLVSSPLPVGQNSLTLQP--------PAPQPVFLSH 359
             ++T +P   G          +  T+  +P P G  + T  P        P P P     
Sbjct: 2917 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 2976

Query: 360  GVPLHQSVNPPVLPLSQPVGPVNKSVGTSVLPINQTVRPGVLPLTQPVGPINRPVGPGVL 419
                  +    V P   P G   ++  T+ +    TV P   P T    P   P+     
Sbjct: 2977 PTTTPITTTTTVTPTPTPTG--TQTPTTTPITTTTTVTPTPTP-TGTQTPTTTPITT-TT 3032

Query: 420  PVSPSVTPGVLQAVSPGVLSVSRAVPSGVLPAGQMTPAGQ--MTPAGVIPGQTATSGVLP 477
             V+P+ TP   Q  +   ++ +  V     P G  TP      T   V P  T T    P
Sbjct: 3033 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 3092

Query: 478  TGQMVQSGVLPVGQTAPSRVLPPGQTAPLRVISA--GQVVPSGLLSPNQT-VSSSAVVPV 534
            T   + +         P+    P  T P+   +       P+G  +P  T ++++  V  
Sbjct: 3093 TTTPITTTTTVTPTPTPTGTQTP-TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3151

Query: 535  NQGVNSGVLQLSQPVVSGVLPVGQPVRPGVLQLNQT---VGTNILPVNQPVRPGASQNTT 591
                       + P+ +       P   G      T     T + P   P        T 
Sbjct: 3152 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3211

Query: 592  FLTSGSILRQLIPTGKQVNGIPTYTLAPVSVTLPVPPGGLATVAPPQMPI 641
              T+ ++     PTG Q    PT T    + T+   P    T  P   PI
Sbjct: 3212 ITTTTTVTPTPTPTGTQT---PTTTPITTTTTVTPTPTPTGTQTPTTTPI 3258



 Score = 49.3 bits (116), Expect = 2e-05
 Identities = 83/410 (20%), Positives = 127/410 (30%), Gaps = 42/410 (10%)

Query: 258  TGLLKQTHIAPKPAAHLAAPANGSAPSAPAQPPCFHLALPQNSPSPAAGQ-PVTVAQGAP 316
            T +   T + P P          +    P   P         +P+P   Q P T      
Sbjct: 2888 TPITTTTTVTPTPTP--------TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 2939

Query: 317  GSLTHSPPAAGQ---------SHMTLVSSPLPVGQNSLTLQP--------PAPQPVFLSH 359
             ++T +P   G          +  T+  +P P G  + T  P        P P P     
Sbjct: 2940 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 2999

Query: 360  GVPLHQSVNPPVLPLSQPVGPVNKSVGTSVLPINQTVRPGVLPLTQPVGPINRPVGPGVL 419
                  +    V P   P G   ++  T+ +    TV P   P T    P   P+     
Sbjct: 3000 PTTTPITTTTTVTPTPTPTG--TQTPTTTPITTTTTVTPTPTP-TGTQTPTTTPITT-TT 3055

Query: 420  PVSPSVTPGVLQAVSPGVLSVSRAVPSGVLPAGQMTPAGQ--MTPAGVIPGQTATSGVLP 477
             V+P+ TP   Q  +   ++ +  V     P G  TP      T   V P  T T    P
Sbjct: 3056 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 3115

Query: 478  TGQMVQSGVLPVGQTAPSRVLPPGQTAPLRVISA--GQVVPSGLLSPNQT-VSSSAVVPV 534
            T   + +         P+    P  T P+   +       P+G  +P  T ++++  V  
Sbjct: 3116 TTTPITTTTTVTPTPTPTGTQTP-TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3174

Query: 535  NQGVNSGVLQLSQPVVSGVLPVGQPVRPGVLQLNQT---VGTNILPVNQPVRPGASQNTT 591
                       + P+ +       P   G      T     T + P   P        T 
Sbjct: 3175 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3234

Query: 592  FLTSGSILRQLIPTGKQVNGIPTYTLAPVSVTLPVPPGGLATVAPPQMPI 641
              T+ ++     PTG Q    PT T    + T+   P    T  P   PI
Sbjct: 3235 ITTTTTVTPTPTPTGTQT---PTTTPITTTTTVTPTPTPTGTQTPTTTPI 3281



 Score = 49.3 bits (116), Expect = 2e-05
 Identities = 83/410 (20%), Positives = 127/410 (30%), Gaps = 42/410 (10%)

Query: 258  TGLLKQTHIAPKPAAHLAAPANGSAPSAPAQPPCFHLALPQNSPSPAAGQ-PVTVAQGAP 316
            T +   T + P P          +    P   P         +P+P   Q P T      
Sbjct: 2911 TPITTTTTVTPTPTP--------TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 2962

Query: 317  GSLTHSPPAAGQ---------SHMTLVSSPLPVGQNSLTLQP--------PAPQPVFLSH 359
             ++T +P   G          +  T+  +P P G  + T  P        P P P     
Sbjct: 2963 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 3022

Query: 360  GVPLHQSVNPPVLPLSQPVGPVNKSVGTSVLPINQTVRPGVLPLTQPVGPINRPVGPGVL 419
                  +    V P   P G   ++  T+ +    TV P   P T    P   P+     
Sbjct: 3023 PTTTPITTTTTVTPTPTPTG--TQTPTTTPITTTTTVTPTPTP-TGTQTPTTTPITT-TT 3078

Query: 420  PVSPSVTPGVLQAVSPGVLSVSRAVPSGVLPAGQMTPAGQ--MTPAGVIPGQTATSGVLP 477
             V+P+ TP   Q  +   ++ +  V     P G  TP      T   V P  T T    P
Sbjct: 3079 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 3138

Query: 478  TGQMVQSGVLPVGQTAPSRVLPPGQTAPLRVISA--GQVVPSGLLSPNQT-VSSSAVVPV 534
            T   + +         P+    P  T P+   +       P+G  +P  T ++++  V  
Sbjct: 3139 TTTPITTTTTVTPTPTPTGTQTP-TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3197

Query: 535  NQGVNSGVLQLSQPVVSGVLPVGQPVRPGVLQLNQT---VGTNILPVNQPVRPGASQNTT 591
                       + P+ +       P   G      T     T + P   P        T 
Sbjct: 3198 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3257

Query: 592  FLTSGSILRQLIPTGKQVNGIPTYTLAPVSVTLPVPPGGLATVAPPQMPI 641
              T+ ++     PTG Q    PT T    + T+   P    T  P   PI
Sbjct: 3258 ITTTTTVTPTPTPTGTQT---PTTTPITTTTTVTPTPTPTGTQTPTTTPI 3304



 Score = 49.3 bits (116), Expect = 2e-05
 Identities = 83/410 (20%), Positives = 127/410 (30%), Gaps = 42/410 (10%)

Query: 258  TGLLKQTHIAPKPAAHLAAPANGSAPSAPAQPPCFHLALPQNSPSPAAGQ-PVTVAQGAP 316
            T +   T + P P          +    P   P         +P+P   Q P T      
Sbjct: 2934 TPITTTTTVTPTPTP--------TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 2985

Query: 317  GSLTHSPPAAGQ---------SHMTLVSSPLPVGQNSLTLQP--------PAPQPVFLSH 359
             ++T +P   G          +  T+  +P P G  + T  P        P P P     
Sbjct: 2986 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 3045

Query: 360  GVPLHQSVNPPVLPLSQPVGPVNKSVGTSVLPINQTVRPGVLPLTQPVGPINRPVGPGVL 419
                  +    V P   P G   ++  T+ +    TV P   P T    P   P+     
Sbjct: 3046 PTTTPITTTTTVTPTPTPTG--TQTPTTTPITTTTTVTPTPTP-TGTQTPTTTPITT-TT 3101

Query: 420  PVSPSVTPGVLQAVSPGVLSVSRAVPSGVLPAGQMTPAGQ--MTPAGVIPGQTATSGVLP 477
             V+P+ TP   Q  +   ++ +  V     P G  TP      T   V P  T T    P
Sbjct: 3102 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 3161

Query: 478  TGQMVQSGVLPVGQTAPSRVLPPGQTAPLRVISA--GQVVPSGLLSPNQT-VSSSAVVPV 534
            T   + +         P+    P  T P+   +       P+G  +P  T ++++  V  
Sbjct: 3162 TTTPITTTTTVTPTPTPTGTQTP-TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3220

Query: 535  NQGVNSGVLQLSQPVVSGVLPVGQPVRPGVLQLNQT---VGTNILPVNQPVRPGASQNTT 591
                       + P+ +       P   G      T     T + P   P        T 
Sbjct: 3221 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3280

Query: 592  FLTSGSILRQLIPTGKQVNGIPTYTLAPVSVTLPVPPGGLATVAPPQMPI 641
              T+ ++     PTG Q    PT T    + T+   P    T  P   PI
Sbjct: 3281 ITTTTTVTPTPTPTGTQT---PTTTPITTTTTVTPTPTPTGTQTPTTTPI 3327



 Score = 49.3 bits (116), Expect = 2e-05
 Identities = 83/410 (20%), Positives = 127/410 (30%), Gaps = 42/410 (10%)

Query: 258  TGLLKQTHIAPKPAAHLAAPANGSAPSAPAQPPCFHLALPQNSPSPAAGQ-PVTVAQGAP 316
            T +   T + P P          +    P   P         +P+P   Q P T      
Sbjct: 2957 TPITTTTTVTPTPTP--------TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 3008

Query: 317  GSLTHSPPAAGQ---------SHMTLVSSPLPVGQNSLTLQP--------PAPQPVFLSH 359
             ++T +P   G          +  T+  +P P G  + T  P        P P P     
Sbjct: 3009 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 3068

Query: 360  GVPLHQSVNPPVLPLSQPVGPVNKSVGTSVLPINQTVRPGVLPLTQPVGPINRPVGPGVL 419
                  +    V P   P G   ++  T+ +    TV P   P T    P   P+     
Sbjct: 3069 PTTTPITTTTTVTPTPTPTG--TQTPTTTPITTTTTVTPTPTP-TGTQTPTTTPITT-TT 3124

Query: 420  PVSPSVTPGVLQAVSPGVLSVSRAVPSGVLPAGQMTPAGQ--MTPAGVIPGQTATSGVLP 477
             V+P+ TP   Q  +   ++ +  V     P G  TP      T   V P  T T    P
Sbjct: 3125 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 3184

Query: 478  TGQMVQSGVLPVGQTAPSRVLPPGQTAPLRVISA--GQVVPSGLLSPNQT-VSSSAVVPV 534
            T   + +         P+    P  T P+   +       P+G  +P  T ++++  V  
Sbjct: 3185 TTTPITTTTTVTPTPTPTGTQTP-TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3243

Query: 535  NQGVNSGVLQLSQPVVSGVLPVGQPVRPGVLQLNQT---VGTNILPVNQPVRPGASQNTT 591
                       + P+ +       P   G      T     T + P   P        T 
Sbjct: 3244 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3303

Query: 592  FLTSGSILRQLIPTGKQVNGIPTYTLAPVSVTLPVPPGGLATVAPPQMPI 641
              T+ ++     PTG Q    PT T    + T+   P    T  P   PI
Sbjct: 3304 ITTTTTVTPTPTPTGTQT---PTTTPITTTTTVTPTPTPTGTQTPTTTPI 3350



 Score = 49.3 bits (116), Expect = 2e-05
 Identities = 83/410 (20%), Positives = 127/410 (30%), Gaps = 42/410 (10%)

Query: 258  TGLLKQTHIAPKPAAHLAAPANGSAPSAPAQPPCFHLALPQNSPSPAAGQ-PVTVAQGAP 316
            T +   T + P P          +    P   P         +P+P   Q P T      
Sbjct: 2980 TPITTTTTVTPTPTP--------TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 3031

Query: 317  GSLTHSPPAAGQ---------SHMTLVSSPLPVGQNSLTLQP--------PAPQPVFLSH 359
             ++T +P   G          +  T+  +P P G  + T  P        P P P     
Sbjct: 3032 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 3091

Query: 360  GVPLHQSVNPPVLPLSQPVGPVNKSVGTSVLPINQTVRPGVLPLTQPVGPINRPVGPGVL 419
                  +    V P   P G   ++  T+ +    TV P   P T    P   P+     
Sbjct: 3092 PTTTPITTTTTVTPTPTPTG--TQTPTTTPITTTTTVTPTPTP-TGTQTPTTTPITT-TT 3147

Query: 420  PVSPSVTPGVLQAVSPGVLSVSRAVPSGVLPAGQMTPAGQ--MTPAGVIPGQTATSGVLP 477
             V+P+ TP   Q  +   ++ +  V     P G  TP      T   V P  T T    P
Sbjct: 3148 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 3207

Query: 478  TGQMVQSGVLPVGQTAPSRVLPPGQTAPLRVISA--GQVVPSGLLSPNQT-VSSSAVVPV 534
            T   + +         P+    P  T P+   +       P+G  +P  T ++++  V  
Sbjct: 3208 TTTPITTTTTVTPTPTPTGTQTP-TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3266

Query: 535  NQGVNSGVLQLSQPVVSGVLPVGQPVRPGVLQLNQT---VGTNILPVNQPVRPGASQNTT 591
                       + P+ +       P   G      T     T + P   P        T 
Sbjct: 3267 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3326

Query: 592  FLTSGSILRQLIPTGKQVNGIPTYTLAPVSVTLPVPPGGLATVAPPQMPI 641
              T+ ++     PTG Q    PT T    + T+   P    T  P   PI
Sbjct: 3327 ITTTTTVTPTPTPTGTQT---PTTTPITTTTTVTPTPTPTGTQTPTTTPI 3373



 Score = 49.3 bits (116), Expect = 2e-05
 Identities = 83/410 (20%), Positives = 127/410 (30%), Gaps = 42/410 (10%)

Query: 258  TGLLKQTHIAPKPAAHLAAPANGSAPSAPAQPPCFHLALPQNSPSPAAGQ-PVTVAQGAP 316
            T +   T + P P          +    P   P         +P+P   Q P T      
Sbjct: 3003 TPITTTTTVTPTPTP--------TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 3054

Query: 317  GSLTHSPPAAGQ---------SHMTLVSSPLPVGQNSLTLQP--------PAPQPVFLSH 359
             ++T +P   G          +  T+  +P P G  + T  P        P P P     
Sbjct: 3055 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 3114

Query: 360  GVPLHQSVNPPVLPLSQPVGPVNKSVGTSVLPINQTVRPGVLPLTQPVGPINRPVGPGVL 419
                  +    V P   P G   ++  T+ +    TV P   P T    P   P+     
Sbjct: 3115 PTTTPITTTTTVTPTPTPTG--TQTPTTTPITTTTTVTPTPTP-TGTQTPTTTPITT-TT 3170

Query: 420  PVSPSVTPGVLQAVSPGVLSVSRAVPSGVLPAGQMTPAGQ--MTPAGVIPGQTATSGVLP 477
             V+P+ TP   Q  +   ++ +  V     P G  TP      T   V P  T T    P
Sbjct: 3171 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 3230

Query: 478  TGQMVQSGVLPVGQTAPSRVLPPGQTAPLRVISA--GQVVPSGLLSPNQT-VSSSAVVPV 534
            T   + +         P+    P  T P+   +       P+G  +P  T ++++  V  
Sbjct: 3231 TTTPITTTTTVTPTPTPTGTQTP-TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3289

Query: 535  NQGVNSGVLQLSQPVVSGVLPVGQPVRPGVLQLNQT---VGTNILPVNQPVRPGASQNTT 591
                       + P+ +       P   G      T     T + P   P        T 
Sbjct: 3290 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3349

Query: 592  FLTSGSILRQLIPTGKQVNGIPTYTLAPVSVTLPVPPGGLATVAPPQMPI 641
              T+ ++     PTG Q    PT T    + T+   P    T  P   PI
Sbjct: 3350 ITTTTTVTPTPTPTGTQT---PTTTPITTTTTVTPTPTPTGTQTPTTTPI 3396



 Score = 49.3 bits (116), Expect = 2e-05
 Identities = 83/410 (20%), Positives = 127/410 (30%), Gaps = 42/410 (10%)

Query: 258  TGLLKQTHIAPKPAAHLAAPANGSAPSAPAQPPCFHLALPQNSPSPAAGQ-PVTVAQGAP 316
            T +   T + P P          +    P   P         +P+P   Q P T      
Sbjct: 3026 TPITTTTTVTPTPTP--------TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 3077

Query: 317  GSLTHSPPAAGQ---------SHMTLVSSPLPVGQNSLTLQP--------PAPQPVFLSH 359
             ++T +P   G          +  T+  +P P G  + T  P        P P P     
Sbjct: 3078 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 3137

Query: 360  GVPLHQSVNPPVLPLSQPVGPVNKSVGTSVLPINQTVRPGVLPLTQPVGPINRPVGPGVL 419
                  +    V P   P G   ++  T+ +    TV P   P T    P   P+     
Sbjct: 3138 PTTTPITTTTTVTPTPTPTG--TQTPTTTPITTTTTVTPTPTP-TGTQTPTTTPITT-TT 3193

Query: 420  PVSPSVTPGVLQAVSPGVLSVSRAVPSGVLPAGQMTPAGQ--MTPAGVIPGQTATSGVLP 477
             V+P+ TP   Q  +   ++ +  V     P G  TP      T   V P  T T    P
Sbjct: 3194 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 3253

Query: 478  TGQMVQSGVLPVGQTAPSRVLPPGQTAPLRVISA--GQVVPSGLLSPNQT-VSSSAVVPV 534
            T   + +         P+    P  T P+   +       P+G  +P  T ++++  V  
Sbjct: 3254 TTTPITTTTTVTPTPTPTGTQTP-TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3312

Query: 535  NQGVNSGVLQLSQPVVSGVLPVGQPVRPGVLQLNQT---VGTNILPVNQPVRPGASQNTT 591
                       + P+ +       P   G      T     T + P   P        T 
Sbjct: 3313 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3372

Query: 592  FLTSGSILRQLIPTGKQVNGIPTYTLAPVSVTLPVPPGGLATVAPPQMPI 641
              T+ ++     PTG Q    PT T    + T+   P    T  P   PI
Sbjct: 3373 ITTTTTVTPTPTPTGTQT---PTTTPITTTTTVTPTPTPTGTQTPTTTPI 3419



 Score = 49.3 bits (116), Expect = 2e-05
 Identities = 83/410 (20%), Positives = 127/410 (30%), Gaps = 42/410 (10%)

Query: 258  TGLLKQTHIAPKPAAHLAAPANGSAPSAPAQPPCFHLALPQNSPSPAAGQ-PVTVAQGAP 316
            T +   T + P P          +    P   P         +P+P   Q P T      
Sbjct: 3049 TPITTTTTVTPTPTP--------TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 3100

Query: 317  GSLTHSPPAAGQ---------SHMTLVSSPLPVGQNSLTLQP--------PAPQPVFLSH 359
             ++T +P   G          +  T+  +P P G  + T  P        P P P     
Sbjct: 3101 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 3160

Query: 360  GVPLHQSVNPPVLPLSQPVGPVNKSVGTSVLPINQTVRPGVLPLTQPVGPINRPVGPGVL 419
                  +    V P   P G   ++  T+ +    TV P   P T    P   P+     
Sbjct: 3161 PTTTPITTTTTVTPTPTPTG--TQTPTTTPITTTTTVTPTPTP-TGTQTPTTTPITT-TT 3216

Query: 420  PVSPSVTPGVLQAVSPGVLSVSRAVPSGVLPAGQMTPAGQ--MTPAGVIPGQTATSGVLP 477
             V+P+ TP   Q  +   ++ +  V     P G  TP      T   V P  T T    P
Sbjct: 3217 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 3276

Query: 478  TGQMVQSGVLPVGQTAPSRVLPPGQTAPLRVISA--GQVVPSGLLSPNQT-VSSSAVVPV 534
            T   + +         P+    P  T P+   +       P+G  +P  T ++++  V  
Sbjct: 3277 TTTPITTTTTVTPTPTPTGTQTP-TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3335

Query: 535  NQGVNSGVLQLSQPVVSGVLPVGQPVRPGVLQLNQT---VGTNILPVNQPVRPGASQNTT 591
                       + P+ +       P   G      T     T + P   P        T 
Sbjct: 3336 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3395

Query: 592  FLTSGSILRQLIPTGKQVNGIPTYTLAPVSVTLPVPPGGLATVAPPQMPI 641
              T+ ++     PTG Q    PT T    + T+   P    T  P   PI
Sbjct: 3396 ITTTTTVTPTPTPTGTQT---PTTTPITTTTTVTPTPTPTGTQTPTTTPI 3442



 Score = 49.3 bits (116), Expect = 2e-05
 Identities = 83/410 (20%), Positives = 127/410 (30%), Gaps = 42/410 (10%)

Query: 258  TGLLKQTHIAPKPAAHLAAPANGSAPSAPAQPPCFHLALPQNSPSPAAGQ-PVTVAQGAP 316
            T +   T + P P          +    P   P         +P+P   Q P T      
Sbjct: 3072 TPITTTTTVTPTPTP--------TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 3123

Query: 317  GSLTHSPPAAGQ---------SHMTLVSSPLPVGQNSLTLQP--------PAPQPVFLSH 359
             ++T +P   G          +  T+  +P P G  + T  P        P P P     
Sbjct: 3124 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 3183

Query: 360  GVPLHQSVNPPVLPLSQPVGPVNKSVGTSVLPINQTVRPGVLPLTQPVGPINRPVGPGVL 419
                  +    V P   P G   ++  T+ +    TV P   P T    P   P+     
Sbjct: 3184 PTTTPITTTTTVTPTPTPTG--TQTPTTTPITTTTTVTPTPTP-TGTQTPTTTPITT-TT 3239

Query: 420  PVSPSVTPGVLQAVSPGVLSVSRAVPSGVLPAGQMTPAGQ--MTPAGVIPGQTATSGVLP 477
             V+P+ TP   Q  +   ++ +  V     P G  TP      T   V P  T T    P
Sbjct: 3240 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 3299

Query: 478  TGQMVQSGVLPVGQTAPSRVLPPGQTAPLRVISA--GQVVPSGLLSPNQT-VSSSAVVPV 534
            T   + +         P+    P  T P+   +       P+G  +P  T ++++  V  
Sbjct: 3300 TTTPITTTTTVTPTPTPTGTQTP-TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3358

Query: 535  NQGVNSGVLQLSQPVVSGVLPVGQPVRPGVLQLNQT---VGTNILPVNQPVRPGASQNTT 591
                       + P+ +       P   G      T     T + P   P        T 
Sbjct: 3359 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3418

Query: 592  FLTSGSILRQLIPTGKQVNGIPTYTLAPVSVTLPVPPGGLATVAPPQMPI 641
              T+ ++     PTG Q    PT T    + T+   P    T  P   PI
Sbjct: 3419 ITTTTTVTPTPTPTGTQT---PTTTPITTTTTVTPTPTPTGTQTPTTTPI 3465



 Score = 49.3 bits (116), Expect = 2e-05
 Identities = 83/410 (20%), Positives = 127/410 (30%), Gaps = 42/410 (10%)

Query: 258  TGLLKQTHIAPKPAAHLAAPANGSAPSAPAQPPCFHLALPQNSPSPAAGQ-PVTVAQGAP 316
            T +   T + P P          +    P   P         +P+P   Q P T      
Sbjct: 3095 TPITTTTTVTPTPTP--------TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 3146

Query: 317  GSLTHSPPAAGQ---------SHMTLVSSPLPVGQNSLTLQP--------PAPQPVFLSH 359
             ++T +P   G          +  T+  +P P G  + T  P        P P P     
Sbjct: 3147 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 3206

Query: 360  GVPLHQSVNPPVLPLSQPVGPVNKSVGTSVLPINQTVRPGVLPLTQPVGPINRPVGPGVL 419
                  +    V P   P G   ++  T+ +    TV P   P T    P   P+     
Sbjct: 3207 PTTTPITTTTTVTPTPTPTG--TQTPTTTPITTTTTVTPTPTP-TGTQTPTTTPITT-TT 3262

Query: 420  PVSPSVTPGVLQAVSPGVLSVSRAVPSGVLPAGQMTPAGQ--MTPAGVIPGQTATSGVLP 477
             V+P+ TP   Q  +   ++ +  V     P G  TP      T   V P  T T    P
Sbjct: 3263 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 3322

Query: 478  TGQMVQSGVLPVGQTAPSRVLPPGQTAPLRVISA--GQVVPSGLLSPNQT-VSSSAVVPV 534
            T   + +         P+    P  T P+   +       P+G  +P  T ++++  V  
Sbjct: 3323 TTTPITTTTTVTPTPTPTGTQTP-TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3381

Query: 535  NQGVNSGVLQLSQPVVSGVLPVGQPVRPGVLQLNQT---VGTNILPVNQPVRPGASQNTT 591
                       + P+ +       P   G      T     T + P   P        T 
Sbjct: 3382 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3441

Query: 592  FLTSGSILRQLIPTGKQVNGIPTYTLAPVSVTLPVPPGGLATVAPPQMPI 641
              T+ ++     PTG Q    PT T    + T+   P    T  P   PI
Sbjct: 3442 ITTTTTVTPTPTPTGTQT---PTTTPITTTTTVTPTPTPTGTQTPTTTPI 3488



 Score = 49.3 bits (116), Expect = 2e-05
 Identities = 83/410 (20%), Positives = 127/410 (30%), Gaps = 42/410 (10%)

Query: 258  TGLLKQTHIAPKPAAHLAAPANGSAPSAPAQPPCFHLALPQNSPSPAAGQ-PVTVAQGAP 316
            T +   T + P P          +    P   P         +P+P   Q P T      
Sbjct: 3118 TPITTTTTVTPTPTP--------TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 3169

Query: 317  GSLTHSPPAAGQ---------SHMTLVSSPLPVGQNSLTLQP--------PAPQPVFLSH 359
             ++T +P   G          +  T+  +P P G  + T  P        P P P     
Sbjct: 3170 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 3229

Query: 360  GVPLHQSVNPPVLPLSQPVGPVNKSVGTSVLPINQTVRPGVLPLTQPVGPINRPVGPGVL 419
                  +    V P   P G   ++  T+ +    TV P   P T    P   P+     
Sbjct: 3230 PTTTPITTTTTVTPTPTPTG--TQTPTTTPITTTTTVTPTPTP-TGTQTPTTTPITT-TT 3285

Query: 420  PVSPSVTPGVLQAVSPGVLSVSRAVPSGVLPAGQMTPAGQ--MTPAGVIPGQTATSGVLP 477
             V+P+ TP   Q  +   ++ +  V     P G  TP      T   V P  T T    P
Sbjct: 3286 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 3345

Query: 478  TGQMVQSGVLPVGQTAPSRVLPPGQTAPLRVISA--GQVVPSGLLSPNQT-VSSSAVVPV 534
            T   + +         P+    P  T P+   +       P+G  +P  T ++++  V  
Sbjct: 3346 TTTPITTTTTVTPTPTPTGTQTP-TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3404

Query: 535  NQGVNSGVLQLSQPVVSGVLPVGQPVRPGVLQLNQT---VGTNILPVNQPVRPGASQNTT 591
                       + P+ +       P   G      T     T + P   P        T 
Sbjct: 3405 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3464

Query: 592  FLTSGSILRQLIPTGKQVNGIPTYTLAPVSVTLPVPPGGLATVAPPQMPI 641
              T+ ++     PTG Q    PT T    + T+   P    T  P   PI
Sbjct: 3465 ITTTTTVTPTPTPTGTQT---PTTTPITTTTTVTPTPTPTGTQTPTTTPI 3511



 Score = 49.3 bits (116), Expect = 2e-05
 Identities = 83/410 (20%), Positives = 127/410 (30%), Gaps = 42/410 (10%)

Query: 258  TGLLKQTHIAPKPAAHLAAPANGSAPSAPAQPPCFHLALPQNSPSPAAGQ-PVTVAQGAP 316
            T +   T + P P          +    P   P         +P+P   Q P T      
Sbjct: 3141 TPITTTTTVTPTPTP--------TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 3192

Query: 317  GSLTHSPPAAGQ---------SHMTLVSSPLPVGQNSLTLQP--------PAPQPVFLSH 359
             ++T +P   G          +  T+  +P P G  + T  P        P P P     
Sbjct: 3193 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 3252

Query: 360  GVPLHQSVNPPVLPLSQPVGPVNKSVGTSVLPINQTVRPGVLPLTQPVGPINRPVGPGVL 419
                  +    V P   P G   ++  T+ +    TV P   P T    P   P+     
Sbjct: 3253 PTTTPITTTTTVTPTPTPTG--TQTPTTTPITTTTTVTPTPTP-TGTQTPTTTPITT-TT 3308

Query: 420  PVSPSVTPGVLQAVSPGVLSVSRAVPSGVLPAGQMTPAGQ--MTPAGVIPGQTATSGVLP 477
             V+P+ TP   Q  +   ++ +  V     P G  TP      T   V P  T T    P
Sbjct: 3309 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 3368

Query: 478  TGQMVQSGVLPVGQTAPSRVLPPGQTAPLRVISA--GQVVPSGLLSPNQT-VSSSAVVPV 534
            T   + +         P+    P  T P+   +       P+G  +P  T ++++  V  
Sbjct: 3369 TTTPITTTTTVTPTPTPTGTQTP-TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3427

Query: 535  NQGVNSGVLQLSQPVVSGVLPVGQPVRPGVLQLNQT---VGTNILPVNQPVRPGASQNTT 591
                       + P+ +       P   G      T     T + P   P        T 
Sbjct: 3428 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3487

Query: 592  FLTSGSILRQLIPTGKQVNGIPTYTLAPVSVTLPVPPGGLATVAPPQMPI 641
              T+ ++     PTG Q    PT T    + T+   P    T  P   PI
Sbjct: 3488 ITTTTTVTPTPTPTGTQT---PTTTPITTTTTVTPTPTPTGTQTPTTTPI 3534



 Score = 49.3 bits (116), Expect = 2e-05
 Identities = 83/410 (20%), Positives = 127/410 (30%), Gaps = 42/410 (10%)

Query: 258  TGLLKQTHIAPKPAAHLAAPANGSAPSAPAQPPCFHLALPQNSPSPAAGQ-PVTVAQGAP 316
            T +   T + P P          +    P   P         +P+P   Q P T      
Sbjct: 3164 TPITTTTTVTPTPTP--------TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 3215

Query: 317  GSLTHSPPAAGQ---------SHMTLVSSPLPVGQNSLTLQP--------PAPQPVFLSH 359
             ++T +P   G          +  T+  +P P G  + T  P        P P P     
Sbjct: 3216 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 3275

Query: 360  GVPLHQSVNPPVLPLSQPVGPVNKSVGTSVLPINQTVRPGVLPLTQPVGPINRPVGPGVL 419
                  +    V P   P G   ++  T+ +    TV P   P T    P   P+     
Sbjct: 3276 PTTTPITTTTTVTPTPTPTG--TQTPTTTPITTTTTVTPTPTP-TGTQTPTTTPITT-TT 3331

Query: 420  PVSPSVTPGVLQAVSPGVLSVSRAVPSGVLPAGQMTPAGQ--MTPAGVIPGQTATSGVLP 477
             V+P+ TP   Q  +   ++ +  V     P G  TP      T   V P  T T    P
Sbjct: 3332 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 3391

Query: 478  TGQMVQSGVLPVGQTAPSRVLPPGQTAPLRVISA--GQVVPSGLLSPNQT-VSSSAVVPV 534
            T   + +         P+    P  T P+   +       P+G  +P  T ++++  V  
Sbjct: 3392 TTTPITTTTTVTPTPTPTGTQTP-TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3450

Query: 535  NQGVNSGVLQLSQPVVSGVLPVGQPVRPGVLQLNQT---VGTNILPVNQPVRPGASQNTT 591
                       + P+ +       P   G      T     T + P   P        T 
Sbjct: 3451 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3510

Query: 592  FLTSGSILRQLIPTGKQVNGIPTYTLAPVSVTLPVPPGGLATVAPPQMPI 641
              T+ ++     PTG Q    PT T    + T+   P    T  P   PI
Sbjct: 3511 ITTTTTVTPTPTPTGTQT---PTTTPITTTTTVTPTPTPTGTQTPTTTPI 3557



 Score = 49.3 bits (116), Expect = 2e-05
 Identities = 83/410 (20%), Positives = 127/410 (30%), Gaps = 42/410 (10%)

Query: 258  TGLLKQTHIAPKPAAHLAAPANGSAPSAPAQPPCFHLALPQNSPSPAAGQ-PVTVAQGAP 316
            T +   T + P P          +    P   P         +P+P   Q P T      
Sbjct: 3187 TPITTTTTVTPTPTP--------TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 3238

Query: 317  GSLTHSPPAAGQ---------SHMTLVSSPLPVGQNSLTLQP--------PAPQPVFLSH 359
             ++T +P   G          +  T+  +P P G  + T  P        P P P     
Sbjct: 3239 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 3298

Query: 360  GVPLHQSVNPPVLPLSQPVGPVNKSVGTSVLPINQTVRPGVLPLTQPVGPINRPVGPGVL 419
                  +    V P   P G   ++  T+ +    TV P   P T    P   P+     
Sbjct: 3299 PTTTPITTTTTVTPTPTPTG--TQTPTTTPITTTTTVTPTPTP-TGTQTPTTTPITT-TT 3354

Query: 420  PVSPSVTPGVLQAVSPGVLSVSRAVPSGVLPAGQMTPAGQ--MTPAGVIPGQTATSGVLP 477
             V+P+ TP   Q  +   ++ +  V     P G  TP      T   V P  T T    P
Sbjct: 3355 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 3414

Query: 478  TGQMVQSGVLPVGQTAPSRVLPPGQTAPLRVISA--GQVVPSGLLSPNQT-VSSSAVVPV 534
            T   + +         P+    P  T P+   +       P+G  +P  T ++++  V  
Sbjct: 3415 TTTPITTTTTVTPTPTPTGTQTP-TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3473

Query: 535  NQGVNSGVLQLSQPVVSGVLPVGQPVRPGVLQLNQT---VGTNILPVNQPVRPGASQNTT 591
                       + P+ +       P   G      T     T + P   P        T 
Sbjct: 3474 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3533

Query: 592  FLTSGSILRQLIPTGKQVNGIPTYTLAPVSVTLPVPPGGLATVAPPQMPI 641
              T+ ++     PTG Q    PT T    + T+   P    T  P   PI
Sbjct: 3534 ITTTTTVTPTPTPTGTQT---PTTTPITTTTTVTPTPTPTGTQTPTTTPI 3580



 Score = 49.3 bits (116), Expect = 2e-05
 Identities = 83/410 (20%), Positives = 127/410 (30%), Gaps = 42/410 (10%)

Query: 258  TGLLKQTHIAPKPAAHLAAPANGSAPSAPAQPPCFHLALPQNSPSPAAGQ-PVTVAQGAP 316
            T +   T + P P          +    P   P         +P+P   Q P T      
Sbjct: 3210 TPITTTTTVTPTPTP--------TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 3261

Query: 317  GSLTHSPPAAGQ---------SHMTLVSSPLPVGQNSLTLQP--------PAPQPVFLSH 359
             ++T +P   G          +  T+  +P P G  + T  P        P P P     
Sbjct: 3262 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 3321

Query: 360  GVPLHQSVNPPVLPLSQPVGPVNKSVGTSVLPINQTVRPGVLPLTQPVGPINRPVGPGVL 419
                  +    V P   P G   ++  T+ +    TV P   P T    P   P+     
Sbjct: 3322 PTTTPITTTTTVTPTPTPTG--TQTPTTTPITTTTTVTPTPTP-TGTQTPTTTPITT-TT 3377

Query: 420  PVSPSVTPGVLQAVSPGVLSVSRAVPSGVLPAGQMTPAGQ--MTPAGVIPGQTATSGVLP 477
             V+P+ TP   Q  +   ++ +  V     P G  TP      T   V P  T T    P
Sbjct: 3378 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 3437

Query: 478  TGQMVQSGVLPVGQTAPSRVLPPGQTAPLRVISA--GQVVPSGLLSPNQT-VSSSAVVPV 534
            T   + +         P+    P  T P+   +       P+G  +P  T ++++  V  
Sbjct: 3438 TTTPITTTTTVTPTPTPTGTQTP-TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3496

Query: 535  NQGVNSGVLQLSQPVVSGVLPVGQPVRPGVLQLNQT---VGTNILPVNQPVRPGASQNTT 591
                       + P+ +       P   G      T     T + P   P        T 
Sbjct: 3497 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3556

Query: 592  FLTSGSILRQLIPTGKQVNGIPTYTLAPVSVTLPVPPGGLATVAPPQMPI 641
              T+ ++     PTG Q    PT T    + T+   P    T  P   PI
Sbjct: 3557 ITTTTTVTPTPTPTGTQT---PTTTPITTTTTVTPTPTPTGTQTPTTTPI 3603



 Score = 49.3 bits (116), Expect = 2e-05
 Identities = 83/410 (20%), Positives = 127/410 (30%), Gaps = 42/410 (10%)

Query: 258  TGLLKQTHIAPKPAAHLAAPANGSAPSAPAQPPCFHLALPQNSPSPAAGQ-PVTVAQGAP 316
            T +   T + P P          +    P   P         +P+P   Q P T      
Sbjct: 3233 TPITTTTTVTPTPTP--------TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 3284

Query: 317  GSLTHSPPAAGQ---------SHMTLVSSPLPVGQNSLTLQP--------PAPQPVFLSH 359
             ++T +P   G          +  T+  +P P G  + T  P        P P P     
Sbjct: 3285 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 3344

Query: 360  GVPLHQSVNPPVLPLSQPVGPVNKSVGTSVLPINQTVRPGVLPLTQPVGPINRPVGPGVL 419
                  +    V P   P G   ++  T+ +    TV P   P T    P   P+     
Sbjct: 3345 PTTTPITTTTTVTPTPTPTG--TQTPTTTPITTTTTVTPTPTP-TGTQTPTTTPITT-TT 3400

Query: 420  PVSPSVTPGVLQAVSPGVLSVSRAVPSGVLPAGQMTPAGQ--MTPAGVIPGQTATSGVLP 477
             V+P+ TP   Q  +   ++ +  V     P G  TP      T   V P  T T    P
Sbjct: 3401 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 3460

Query: 478  TGQMVQSGVLPVGQTAPSRVLPPGQTAPLRVISA--GQVVPSGLLSPNQT-VSSSAVVPV 534
            T   + +         P+    P  T P+   +       P+G  +P  T ++++  V  
Sbjct: 3461 TTTPITTTTTVTPTPTPTGTQTP-TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3519

Query: 535  NQGVNSGVLQLSQPVVSGVLPVGQPVRPGVLQLNQT---VGTNILPVNQPVRPGASQNTT 591
                       + P+ +       P   G      T     T + P   P        T 
Sbjct: 3520 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3579

Query: 592  FLTSGSILRQLIPTGKQVNGIPTYTLAPVSVTLPVPPGGLATVAPPQMPI 641
              T+ ++     PTG Q    PT T    + T+   P    T  P   PI
Sbjct: 3580 ITTTTTVTPTPTPTGTQT---PTTTPITTTTTVTPTPTPTGTQTPTTTPI 3626



 Score = 49.3 bits (116), Expect = 2e-05
 Identities = 83/410 (20%), Positives = 127/410 (30%), Gaps = 42/410 (10%)

Query: 258  TGLLKQTHIAPKPAAHLAAPANGSAPSAPAQPPCFHLALPQNSPSPAAGQ-PVTVAQGAP 316
            T +   T + P P          +    P   P         +P+P   Q P T      
Sbjct: 3256 TPITTTTTVTPTPTP--------TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 3307

Query: 317  GSLTHSPPAAGQ---------SHMTLVSSPLPVGQNSLTLQP--------PAPQPVFLSH 359
             ++T +P   G          +  T+  +P P G  + T  P        P P P     
Sbjct: 3308 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 3367

Query: 360  GVPLHQSVNPPVLPLSQPVGPVNKSVGTSVLPINQTVRPGVLPLTQPVGPINRPVGPGVL 419
                  +    V P   P G   ++  T+ +    TV P   P T    P   P+     
Sbjct: 3368 PTTTPITTTTTVTPTPTPTG--TQTPTTTPITTTTTVTPTPTP-TGTQTPTTTPITT-TT 3423

Query: 420  PVSPSVTPGVLQAVSPGVLSVSRAVPSGVLPAGQMTPAGQ--MTPAGVIPGQTATSGVLP 477
             V+P+ TP   Q  +   ++ +  V     P G  TP      T   V P  T T    P
Sbjct: 3424 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 3483

Query: 478  TGQMVQSGVLPVGQTAPSRVLPPGQTAPLRVISA--GQVVPSGLLSPNQT-VSSSAVVPV 534
            T   + +         P+    P  T P+   +       P+G  +P  T ++++  V  
Sbjct: 3484 TTTPITTTTTVTPTPTPTGTQTP-TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3542

Query: 535  NQGVNSGVLQLSQPVVSGVLPVGQPVRPGVLQLNQT---VGTNILPVNQPVRPGASQNTT 591
                       + P+ +       P   G      T     T + P   P        T 
Sbjct: 3543 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3602

Query: 592  FLTSGSILRQLIPTGKQVNGIPTYTLAPVSVTLPVPPGGLATVAPPQMPI 641
              T+ ++     PTG Q    PT T    + T+   P    T  P   PI
Sbjct: 3603 ITTTTTVTPTPTPTGTQT---PTTTPITTTTTVTPTPTPTGTQTPTTTPI 3649



 Score = 49.3 bits (116), Expect = 2e-05
 Identities = 83/410 (20%), Positives = 127/410 (30%), Gaps = 42/410 (10%)

Query: 258  TGLLKQTHIAPKPAAHLAAPANGSAPSAPAQPPCFHLALPQNSPSPAAGQ-PVTVAQGAP 316
            T +   T + P P          +    P   P         +P+P   Q P T      
Sbjct: 3279 TPITTTTTVTPTPTP--------TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 3330

Query: 317  GSLTHSPPAAGQ---------SHMTLVSSPLPVGQNSLTLQP--------PAPQPVFLSH 359
             ++T +P   G          +  T+  +P P G  + T  P        P P P     
Sbjct: 3331 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 3390

Query: 360  GVPLHQSVNPPVLPLSQPVGPVNKSVGTSVLPINQTVRPGVLPLTQPVGPINRPVGPGVL 419
                  +    V P   P G   ++  T+ +    TV P   P T    P   P+     
Sbjct: 3391 PTTTPITTTTTVTPTPTPTG--TQTPTTTPITTTTTVTPTPTP-TGTQTPTTTPITT-TT 3446

Query: 420  PVSPSVTPGVLQAVSPGVLSVSRAVPSGVLPAGQMTPAGQ--MTPAGVIPGQTATSGVLP 477
             V+P+ TP   Q  +   ++ +  V     P G  TP      T   V P  T T    P
Sbjct: 3447 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 3506

Query: 478  TGQMVQSGVLPVGQTAPSRVLPPGQTAPLRVISA--GQVVPSGLLSPNQT-VSSSAVVPV 534
            T   + +         P+    P  T P+   +       P+G  +P  T ++++  V  
Sbjct: 3507 TTTPITTTTTVTPTPTPTGTQTP-TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3565

Query: 535  NQGVNSGVLQLSQPVVSGVLPVGQPVRPGVLQLNQT---VGTNILPVNQPVRPGASQNTT 591
                       + P+ +       P   G      T     T + P   P        T 
Sbjct: 3566 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3625

Query: 592  FLTSGSILRQLIPTGKQVNGIPTYTLAPVSVTLPVPPGGLATVAPPQMPI 641
              T+ ++     PTG Q    PT T    + T+   P    T  P   PI
Sbjct: 3626 ITTTTTVTPTPTPTGTQT---PTTTPITTTTTVTPTPTPTGTQTPTTTPI 3672



 Score = 49.3 bits (116), Expect = 2e-05
 Identities = 83/410 (20%), Positives = 127/410 (30%), Gaps = 42/410 (10%)

Query: 258  TGLLKQTHIAPKPAAHLAAPANGSAPSAPAQPPCFHLALPQNSPSPAAGQ-PVTVAQGAP 316
            T +   T + P P          +    P   P         +P+P   Q P T      
Sbjct: 3302 TPITTTTTVTPTPTP--------TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 3353

Query: 317  GSLTHSPPAAGQ---------SHMTLVSSPLPVGQNSLTLQP--------PAPQPVFLSH 359
             ++T +P   G          +  T+  +P P G  + T  P        P P P     
Sbjct: 3354 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 3413

Query: 360  GVPLHQSVNPPVLPLSQPVGPVNKSVGTSVLPINQTVRPGVLPLTQPVGPINRPVGPGVL 419
                  +    V P   P G   ++  T+ +    TV P   P T    P   P+     
Sbjct: 3414 PTTTPITTTTTVTPTPTPTG--TQTPTTTPITTTTTVTPTPTP-TGTQTPTTTPITT-TT 3469

Query: 420  PVSPSVTPGVLQAVSPGVLSVSRAVPSGVLPAGQMTPAGQ--MTPAGVIPGQTATSGVLP 477
             V+P+ TP   Q  +   ++ +  V     P G  TP      T   V P  T T    P
Sbjct: 3470 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 3529

Query: 478  TGQMVQSGVLPVGQTAPSRVLPPGQTAPLRVISA--GQVVPSGLLSPNQT-VSSSAVVPV 534
            T   + +         P+    P  T P+   +       P+G  +P  T ++++  V  
Sbjct: 3530 TTTPITTTTTVTPTPTPTGTQTP-TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3588

Query: 535  NQGVNSGVLQLSQPVVSGVLPVGQPVRPGVLQLNQT---VGTNILPVNQPVRPGASQNTT 591
                       + P+ +       P   G      T     T + P   P        T 
Sbjct: 3589 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3648

Query: 592  FLTSGSILRQLIPTGKQVNGIPTYTLAPVSVTLPVPPGGLATVAPPQMPI 641
              T+ ++     PTG Q    PT T    + T+   P    T  P   PI
Sbjct: 3649 ITTTTTVTPTPTPTGTQT---PTTTPITTTTTVTPTPTPTGTQTPTTTPI 3695



 Score = 49.3 bits (116), Expect = 2e-05
 Identities = 83/410 (20%), Positives = 127/410 (30%), Gaps = 42/410 (10%)

Query: 258  TGLLKQTHIAPKPAAHLAAPANGSAPSAPAQPPCFHLALPQNSPSPAAGQ-PVTVAQGAP 316
            T +   T + P P          +    P   P         +P+P   Q P T      
Sbjct: 3325 TPITTTTTVTPTPTP--------TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 3376

Query: 317  GSLTHSPPAAGQ---------SHMTLVSSPLPVGQNSLTLQP--------PAPQPVFLSH 359
             ++T +P   G          +  T+  +P P G  + T  P        P P P     
Sbjct: 3377 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 3436

Query: 360  GVPLHQSVNPPVLPLSQPVGPVNKSVGTSVLPINQTVRPGVLPLTQPVGPINRPVGPGVL 419
                  +    V P   P G   ++  T+ +    TV P   P T    P   P+     
Sbjct: 3437 PTTTPITTTTTVTPTPTPTG--TQTPTTTPITTTTTVTPTPTP-TGTQTPTTTPITT-TT 3492

Query: 420  PVSPSVTPGVLQAVSPGVLSVSRAVPSGVLPAGQMTPAGQ--MTPAGVIPGQTATSGVLP 477
             V+P+ TP   Q  +   ++ +  V     P G  TP      T   V P  T T    P
Sbjct: 3493 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 3552

Query: 478  TGQMVQSGVLPVGQTAPSRVLPPGQTAPLRVISA--GQVVPSGLLSPNQT-VSSSAVVPV 534
            T   + +         P+    P  T P+   +       P+G  +P  T ++++  V  
Sbjct: 3553 TTTPITTTTTVTPTPTPTGTQTP-TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3611

Query: 535  NQGVNSGVLQLSQPVVSGVLPVGQPVRPGVLQLNQT---VGTNILPVNQPVRPGASQNTT 591
                       + P+ +       P   G      T     T + P   P        T 
Sbjct: 3612 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3671

Query: 592  FLTSGSILRQLIPTGKQVNGIPTYTLAPVSVTLPVPPGGLATVAPPQMPI 641
              T+ ++     PTG Q    PT T    + T+   P    T  P   PI
Sbjct: 3672 ITTTTTVTPTPTPTGTQT---PTTTPITTTTTVTPTPTPTGTQTPTTTPI 3718



 Score = 49.3 bits (116), Expect = 2e-05
 Identities = 83/410 (20%), Positives = 127/410 (30%), Gaps = 42/410 (10%)

Query: 258  TGLLKQTHIAPKPAAHLAAPANGSAPSAPAQPPCFHLALPQNSPSPAAGQ-PVTVAQGAP 316
            T +   T + P P          +    P   P         +P+P   Q P T      
Sbjct: 3348 TPITTTTTVTPTPTP--------TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 3399

Query: 317  GSLTHSPPAAGQ---------SHMTLVSSPLPVGQNSLTLQP--------PAPQPVFLSH 359
             ++T +P   G          +  T+  +P P G  + T  P        P P P     
Sbjct: 3400 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 3459

Query: 360  GVPLHQSVNPPVLPLSQPVGPVNKSVGTSVLPINQTVRPGVLPLTQPVGPINRPVGPGVL 419
                  +    V P   P G   ++  T+ +    TV P   P T    P   P+     
Sbjct: 3460 PTTTPITTTTTVTPTPTPTG--TQTPTTTPITTTTTVTPTPTP-TGTQTPTTTPITT-TT 3515

Query: 420  PVSPSVTPGVLQAVSPGVLSVSRAVPSGVLPAGQMTPAGQ--MTPAGVIPGQTATSGVLP 477
             V+P+ TP   Q  +   ++ +  V     P G  TP      T   V P  T T    P
Sbjct: 3516 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 3575

Query: 478  TGQMVQSGVLPVGQTAPSRVLPPGQTAPLRVISA--GQVVPSGLLSPNQT-VSSSAVVPV 534
            T   + +         P+    P  T P+   +       P+G  +P  T ++++  V  
Sbjct: 3576 TTTPITTTTTVTPTPTPTGTQTP-TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3634

Query: 535  NQGVNSGVLQLSQPVVSGVLPVGQPVRPGVLQLNQT---VGTNILPVNQPVRPGASQNTT 591
                       + P+ +       P   G      T     T + P   P        T 
Sbjct: 3635 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3694

Query: 592  FLTSGSILRQLIPTGKQVNGIPTYTLAPVSVTLPVPPGGLATVAPPQMPI 641
              T+ ++     PTG Q    PT T    + T+   P    T  P   PI
Sbjct: 3695 ITTTTTVTPTPTPTGTQT---PTTTPITTTTTVTPTPTPTGTQTPTTTPI 3741



 Score = 49.3 bits (116), Expect = 2e-05
 Identities = 83/410 (20%), Positives = 127/410 (30%), Gaps = 42/410 (10%)

Query: 258  TGLLKQTHIAPKPAAHLAAPANGSAPSAPAQPPCFHLALPQNSPSPAAGQ-PVTVAQGAP 316
            T +   T + P P          +    P   P         +P+P   Q P T      
Sbjct: 3371 TPITTTTTVTPTPTP--------TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 3422

Query: 317  GSLTHSPPAAGQ---------SHMTLVSSPLPVGQNSLTLQP--------PAPQPVFLSH 359
             ++T +P   G          +  T+  +P P G  + T  P        P P P     
Sbjct: 3423 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 3482

Query: 360  GVPLHQSVNPPVLPLSQPVGPVNKSVGTSVLPINQTVRPGVLPLTQPVGPINRPVGPGVL 419
                  +    V P   P G   ++  T+ +    TV P   P T    P   P+     
Sbjct: 3483 PTTTPITTTTTVTPTPTPTG--TQTPTTTPITTTTTVTPTPTP-TGTQTPTTTPITT-TT 3538

Query: 420  PVSPSVTPGVLQAVSPGVLSVSRAVPSGVLPAGQMTPAGQ--MTPAGVIPGQTATSGVLP 477
             V+P+ TP   Q  +   ++ +  V     P G  TP      T   V P  T T    P
Sbjct: 3539 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 3598

Query: 478  TGQMVQSGVLPVGQTAPSRVLPPGQTAPLRVISA--GQVVPSGLLSPNQT-VSSSAVVPV 534
            T   + +         P+    P  T P+   +       P+G  +P  T ++++  V  
Sbjct: 3599 TTTPITTTTTVTPTPTPTGTQTP-TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3657

Query: 535  NQGVNSGVLQLSQPVVSGVLPVGQPVRPGVLQLNQT---VGTNILPVNQPVRPGASQNTT 591
                       + P+ +       P   G      T     T + P   P        T 
Sbjct: 3658 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3717

Query: 592  FLTSGSILRQLIPTGKQVNGIPTYTLAPVSVTLPVPPGGLATVAPPQMPI 641
              T+ ++     PTG Q    PT T    + T+   P    T  P   PI
Sbjct: 3718 ITTTTTVTPTPTPTGTQT---PTTTPITTTTTVTPTPTPTGTQTPTTTPI 3764



 Score = 49.3 bits (116), Expect = 2e-05
 Identities = 83/410 (20%), Positives = 127/410 (30%), Gaps = 42/410 (10%)

Query: 258  TGLLKQTHIAPKPAAHLAAPANGSAPSAPAQPPCFHLALPQNSPSPAAGQ-PVTVAQGAP 316
            T +   T + P P          +    P   P         +P+P   Q P T      
Sbjct: 3394 TPITTTTTVTPTPTP--------TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 3445

Query: 317  GSLTHSPPAAGQ---------SHMTLVSSPLPVGQNSLTLQP--------PAPQPVFLSH 359
             ++T +P   G          +  T+  +P P G  + T  P        P P P     
Sbjct: 3446 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 3505

Query: 360  GVPLHQSVNPPVLPLSQPVGPVNKSVGTSVLPINQTVRPGVLPLTQPVGPINRPVGPGVL 419
                  +    V P   P G   ++  T+ +    TV P   P T    P   P+     
Sbjct: 3506 PTTTPITTTTTVTPTPTPTG--TQTPTTTPITTTTTVTPTPTP-TGTQTPTTTPITT-TT 3561

Query: 420  PVSPSVTPGVLQAVSPGVLSVSRAVPSGVLPAGQMTPAGQ--MTPAGVIPGQTATSGVLP 477
             V+P+ TP   Q  +   ++ +  V     P G  TP      T   V P  T T    P
Sbjct: 3562 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 3621

Query: 478  TGQMVQSGVLPVGQTAPSRVLPPGQTAPLRVISA--GQVVPSGLLSPNQT-VSSSAVVPV 534
            T   + +         P+    P  T P+   +       P+G  +P  T ++++  V  
Sbjct: 3622 TTTPITTTTTVTPTPTPTGTQTP-TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3680

Query: 535  NQGVNSGVLQLSQPVVSGVLPVGQPVRPGVLQLNQT---VGTNILPVNQPVRPGASQNTT 591
                       + P+ +       P   G      T     T + P   P        T 
Sbjct: 3681 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3740

Query: 592  FLTSGSILRQLIPTGKQVNGIPTYTLAPVSVTLPVPPGGLATVAPPQMPI 641
              T+ ++     PTG Q    PT T    + T+   P    T  P   PI
Sbjct: 3741 ITTTTTVTPTPTPTGTQT---PTTTPITTTTTVTPTPTPTGTQTPTTTPI 3787



 Score = 49.3 bits (116), Expect = 2e-05
 Identities = 83/410 (20%), Positives = 127/410 (30%), Gaps = 42/410 (10%)

Query: 258  TGLLKQTHIAPKPAAHLAAPANGSAPSAPAQPPCFHLALPQNSPSPAAGQ-PVTVAQGAP 316
            T +   T + P P          +    P   P         +P+P   Q P T      
Sbjct: 3417 TPITTTTTVTPTPTP--------TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 3468

Query: 317  GSLTHSPPAAGQ---------SHMTLVSSPLPVGQNSLTLQP--------PAPQPVFLSH 359
             ++T +P   G          +  T+  +P P G  + T  P        P P P     
Sbjct: 3469 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 3528

Query: 360  GVPLHQSVNPPVLPLSQPVGPVNKSVGTSVLPINQTVRPGVLPLTQPVGPINRPVGPGVL 419
                  +    V P   P G   ++  T+ +    TV P   P T    P   P+     
Sbjct: 3529 PTTTPITTTTTVTPTPTPTG--TQTPTTTPITTTTTVTPTPTP-TGTQTPTTTPITT-TT 3584

Query: 420  PVSPSVTPGVLQAVSPGVLSVSRAVPSGVLPAGQMTPAGQ--MTPAGVIPGQTATSGVLP 477
             V+P+ TP   Q  +   ++ +  V     P G  TP      T   V P  T T    P
Sbjct: 3585 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 3644

Query: 478  TGQMVQSGVLPVGQTAPSRVLPPGQTAPLRVISA--GQVVPSGLLSPNQT-VSSSAVVPV 534
            T   + +         P+    P  T P+   +       P+G  +P  T ++++  V  
Sbjct: 3645 TTTPITTTTTVTPTPTPTGTQTP-TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3703

Query: 535  NQGVNSGVLQLSQPVVSGVLPVGQPVRPGVLQLNQT---VGTNILPVNQPVRPGASQNTT 591
                       + P+ +       P   G      T     T + P   P        T 
Sbjct: 3704 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3763

Query: 592  FLTSGSILRQLIPTGKQVNGIPTYTLAPVSVTLPVPPGGLATVAPPQMPI 641
              T+ ++     PTG Q    PT T    + T+   P    T  P   PI
Sbjct: 3764 ITTTTTVTPTPTPTGTQT---PTTTPITTTTTVTPTPTPTGTQTPTTTPI 3810



 Score = 49.3 bits (116), Expect = 2e-05
 Identities = 83/410 (20%), Positives = 127/410 (30%), Gaps = 42/410 (10%)

Query: 258  TGLLKQTHIAPKPAAHLAAPANGSAPSAPAQPPCFHLALPQNSPSPAAGQ-PVTVAQGAP 316
            T +   T + P P          +    P   P         +P+P   Q P T      
Sbjct: 3440 TPITTTTTVTPTPTP--------TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 3491

Query: 317  GSLTHSPPAAGQ---------SHMTLVSSPLPVGQNSLTLQP--------PAPQPVFLSH 359
             ++T +P   G          +  T+  +P P G  + T  P        P P P     
Sbjct: 3492 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 3551

Query: 360  GVPLHQSVNPPVLPLSQPVGPVNKSVGTSVLPINQTVRPGVLPLTQPVGPINRPVGPGVL 419
                  +    V P   P G   ++  T+ +    TV P   P T    P   P+     
Sbjct: 3552 PTTTPITTTTTVTPTPTPTG--TQTPTTTPITTTTTVTPTPTP-TGTQTPTTTPITT-TT 3607

Query: 420  PVSPSVTPGVLQAVSPGVLSVSRAVPSGVLPAGQMTPAGQ--MTPAGVIPGQTATSGVLP 477
             V+P+ TP   Q  +   ++ +  V     P G  TP      T   V P  T T    P
Sbjct: 3608 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 3667

Query: 478  TGQMVQSGVLPVGQTAPSRVLPPGQTAPLRVISA--GQVVPSGLLSPNQT-VSSSAVVPV 534
            T   + +         P+    P  T P+   +       P+G  +P  T ++++  V  
Sbjct: 3668 TTTPITTTTTVTPTPTPTGTQTP-TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3726

Query: 535  NQGVNSGVLQLSQPVVSGVLPVGQPVRPGVLQLNQT---VGTNILPVNQPVRPGASQNTT 591
                       + P+ +       P   G      T     T + P   P        T 
Sbjct: 3727 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3786

Query: 592  FLTSGSILRQLIPTGKQVNGIPTYTLAPVSVTLPVPPGGLATVAPPQMPI 641
              T+ ++     PTG Q    PT T    + T+   P    T  P   PI
Sbjct: 3787 ITTTTTVTPTPTPTGTQT---PTTTPITTTTTVTPTPTPTGTQTPTTTPI 3833



 Score = 49.3 bits (116), Expect = 2e-05
 Identities = 83/410 (20%), Positives = 127/410 (30%), Gaps = 42/410 (10%)

Query: 258  TGLLKQTHIAPKPAAHLAAPANGSAPSAPAQPPCFHLALPQNSPSPAAGQ-PVTVAQGAP 316
            T +   T + P P          +    P   P         +P+P   Q P T      
Sbjct: 3463 TPITTTTTVTPTPTP--------TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 3514

Query: 317  GSLTHSPPAAGQ---------SHMTLVSSPLPVGQNSLTLQP--------PAPQPVFLSH 359
             ++T +P   G          +  T+  +P P G  + T  P        P P P     
Sbjct: 3515 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 3574

Query: 360  GVPLHQSVNPPVLPLSQPVGPVNKSVGTSVLPINQTVRPGVLPLTQPVGPINRPVGPGVL 419
                  +    V P   P G   ++  T+ +    TV P   P T    P   P+     
Sbjct: 3575 PTTTPITTTTTVTPTPTPTG--TQTPTTTPITTTTTVTPTPTP-TGTQTPTTTPITT-TT 3630

Query: 420  PVSPSVTPGVLQAVSPGVLSVSRAVPSGVLPAGQMTPAGQ--MTPAGVIPGQTATSGVLP 477
             V+P+ TP   Q  +   ++ +  V     P G  TP      T   V P  T T    P
Sbjct: 3631 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 3690

Query: 478  TGQMVQSGVLPVGQTAPSRVLPPGQTAPLRVISA--GQVVPSGLLSPNQT-VSSSAVVPV 534
            T   + +         P+    P  T P+   +       P+G  +P  T ++++  V  
Sbjct: 3691 TTTPITTTTTVTPTPTPTGTQTP-TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3749

Query: 535  NQGVNSGVLQLSQPVVSGVLPVGQPVRPGVLQLNQT---VGTNILPVNQPVRPGASQNTT 591
                       + P+ +       P   G      T     T + P   P        T 
Sbjct: 3750 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3809

Query: 592  FLTSGSILRQLIPTGKQVNGIPTYTLAPVSVTLPVPPGGLATVAPPQMPI 641
              T+ ++     PTG Q    PT T    + T+   P    T  P   PI
Sbjct: 3810 ITTTTTVTPTPTPTGTQT---PTTTPITTTTTVTPTPTPTGTQTPTTTPI 3856



 Score = 49.3 bits (116), Expect = 2e-05
 Identities = 83/410 (20%), Positives = 127/410 (30%), Gaps = 42/410 (10%)

Query: 258  TGLLKQTHIAPKPAAHLAAPANGSAPSAPAQPPCFHLALPQNSPSPAAGQ-PVTVAQGAP 316
            T +   T + P P          +    P   P         +P+P   Q P T      
Sbjct: 3486 TPITTTTTVTPTPTP--------TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 3537

Query: 317  GSLTHSPPAAGQ---------SHMTLVSSPLPVGQNSLTLQP--------PAPQPVFLSH 359
             ++T +P   G          +  T+  +P P G  + T  P        P P P     
Sbjct: 3538 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 3597

Query: 360  GVPLHQSVNPPVLPLSQPVGPVNKSVGTSVLPINQTVRPGVLPLTQPVGPINRPVGPGVL 419
                  +    V P   P G   ++  T+ +    TV P   P T    P   P+     
Sbjct: 3598 PTTTPITTTTTVTPTPTPTG--TQTPTTTPITTTTTVTPTPTP-TGTQTPTTTPITT-TT 3653

Query: 420  PVSPSVTPGVLQAVSPGVLSVSRAVPSGVLPAGQMTPAGQ--MTPAGVIPGQTATSGVLP 477
             V+P+ TP   Q  +   ++ +  V     P G  TP      T   V P  T T    P
Sbjct: 3654 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 3713

Query: 478  TGQMVQSGVLPVGQTAPSRVLPPGQTAPLRVISA--GQVVPSGLLSPNQT-VSSSAVVPV 534
            T   + +         P+    P  T P+   +       P+G  +P  T ++++  V  
Sbjct: 3714 TTTPITTTTTVTPTPTPTGTQTP-TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3772

Query: 535  NQGVNSGVLQLSQPVVSGVLPVGQPVRPGVLQLNQT---VGTNILPVNQPVRPGASQNTT 591
                       + P+ +       P   G      T     T + P   P        T 
Sbjct: 3773 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3832

Query: 592  FLTSGSILRQLIPTGKQVNGIPTYTLAPVSVTLPVPPGGLATVAPPQMPI 641
              T+ ++     PTG Q    PT T    + T+   P    T  P   PI
Sbjct: 3833 ITTTTTVTPTPTPTGTQT---PTTTPITTTTTVTPTPTPTGTQTPTTTPI 3879



 Score = 49.3 bits (116), Expect = 2e-05
 Identities = 83/410 (20%), Positives = 127/410 (30%), Gaps = 42/410 (10%)

Query: 258  TGLLKQTHIAPKPAAHLAAPANGSAPSAPAQPPCFHLALPQNSPSPAAGQ-PVTVAQGAP 316
            T +   T + P P          +    P   P         +P+P   Q P T      
Sbjct: 3509 TPITTTTTVTPTPTP--------TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 3560

Query: 317  GSLTHSPPAAGQ---------SHMTLVSSPLPVGQNSLTLQP--------PAPQPVFLSH 359
             ++T +P   G          +  T+  +P P G  + T  P        P P P     
Sbjct: 3561 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 3620

Query: 360  GVPLHQSVNPPVLPLSQPVGPVNKSVGTSVLPINQTVRPGVLPLTQPVGPINRPVGPGVL 419
                  +    V P   P G   ++  T+ +    TV P   P T    P   P+     
Sbjct: 3621 PTTTPITTTTTVTPTPTPTG--TQTPTTTPITTTTTVTPTPTP-TGTQTPTTTPITT-TT 3676

Query: 420  PVSPSVTPGVLQAVSPGVLSVSRAVPSGVLPAGQMTPAGQ--MTPAGVIPGQTATSGVLP 477
             V+P+ TP   Q  +   ++ +  V     P G  TP      T   V P  T T    P
Sbjct: 3677 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 3736

Query: 478  TGQMVQSGVLPVGQTAPSRVLPPGQTAPLRVISA--GQVVPSGLLSPNQT-VSSSAVVPV 534
            T   + +         P+    P  T P+   +       P+G  +P  T ++++  V  
Sbjct: 3737 TTTPITTTTTVTPTPTPTGTQTP-TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3795

Query: 535  NQGVNSGVLQLSQPVVSGVLPVGQPVRPGVLQLNQT---VGTNILPVNQPVRPGASQNTT 591
                       + P+ +       P   G      T     T + P   P        T 
Sbjct: 3796 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3855

Query: 592  FLTSGSILRQLIPTGKQVNGIPTYTLAPVSVTLPVPPGGLATVAPPQMPI 641
              T+ ++     PTG Q    PT T    + T+   P    T  P   PI
Sbjct: 3856 ITTTTTVTPTPTPTGTQT---PTTTPITTTTTVTPTPTPTGTQTPTTTPI 3902



 Score = 49.3 bits (116), Expect = 2e-05
 Identities = 83/410 (20%), Positives = 127/410 (30%), Gaps = 42/410 (10%)

Query: 258  TGLLKQTHIAPKPAAHLAAPANGSAPSAPAQPPCFHLALPQNSPSPAAGQ-PVTVAQGAP 316
            T +   T + P P          +    P   P         +P+P   Q P T      
Sbjct: 3532 TPITTTTTVTPTPTP--------TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 3583

Query: 317  GSLTHSPPAAGQ---------SHMTLVSSPLPVGQNSLTLQP--------PAPQPVFLSH 359
             ++T +P   G          +  T+  +P P G  + T  P        P P P     
Sbjct: 3584 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 3643

Query: 360  GVPLHQSVNPPVLPLSQPVGPVNKSVGTSVLPINQTVRPGVLPLTQPVGPINRPVGPGVL 419
                  +    V P   P G   ++  T+ +    TV P   P T    P   P+     
Sbjct: 3644 PTTTPITTTTTVTPTPTPTG--TQTPTTTPITTTTTVTPTPTP-TGTQTPTTTPITT-TT 3699

Query: 420  PVSPSVTPGVLQAVSPGVLSVSRAVPSGVLPAGQMTPAGQ--MTPAGVIPGQTATSGVLP 477
             V+P+ TP   Q  +   ++ +  V     P G  TP      T   V P  T T    P
Sbjct: 3700 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 3759

Query: 478  TGQMVQSGVLPVGQTAPSRVLPPGQTAPLRVISA--GQVVPSGLLSPNQT-VSSSAVVPV 534
            T   + +         P+    P  T P+   +       P+G  +P  T ++++  V  
Sbjct: 3760 TTTPITTTTTVTPTPTPTGTQTP-TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3818

Query: 535  NQGVNSGVLQLSQPVVSGVLPVGQPVRPGVLQLNQT---VGTNILPVNQPVRPGASQNTT 591
                       + P+ +       P   G      T     T + P   P        T 
Sbjct: 3819 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3878

Query: 592  FLTSGSILRQLIPTGKQVNGIPTYTLAPVSVTLPVPPGGLATVAPPQMPI 641
              T+ ++     PTG Q    PT T    + T+   P    T  P   PI
Sbjct: 3879 ITTTTTVTPTPTPTGTQT---PTTTPITTTTTVTPTPTPTGTQTPTTTPI 3925



 Score = 49.3 bits (116), Expect = 2e-05
 Identities = 83/410 (20%), Positives = 127/410 (30%), Gaps = 42/410 (10%)

Query: 258  TGLLKQTHIAPKPAAHLAAPANGSAPSAPAQPPCFHLALPQNSPSPAAGQ-PVTVAQGAP 316
            T +   T + P P          +    P   P         +P+P   Q P T      
Sbjct: 3555 TPITTTTTVTPTPTP--------TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 3606

Query: 317  GSLTHSPPAAGQ---------SHMTLVSSPLPVGQNSLTLQP--------PAPQPVFLSH 359
             ++T +P   G          +  T+  +P P G  + T  P        P P P     
Sbjct: 3607 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 3666

Query: 360  GVPLHQSVNPPVLPLSQPVGPVNKSVGTSVLPINQTVRPGVLPLTQPVGPINRPVGPGVL 419
                  +    V P   P G   ++  T+ +    TV P   P T    P   P+     
Sbjct: 3667 PTTTPITTTTTVTPTPTPTG--TQTPTTTPITTTTTVTPTPTP-TGTQTPTTTPITT-TT 3722

Query: 420  PVSPSVTPGVLQAVSPGVLSVSRAVPSGVLPAGQMTPAGQ--MTPAGVIPGQTATSGVLP 477
             V+P+ TP   Q  +   ++ +  V     P G  TP      T   V P  T T    P
Sbjct: 3723 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 3782

Query: 478  TGQMVQSGVLPVGQTAPSRVLPPGQTAPLRVISA--GQVVPSGLLSPNQT-VSSSAVVPV 534
            T   + +         P+    P  T P+   +       P+G  +P  T ++++  V  
Sbjct: 3783 TTTPITTTTTVTPTPTPTGTQTP-TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3841

Query: 535  NQGVNSGVLQLSQPVVSGVLPVGQPVRPGVLQLNQT---VGTNILPVNQPVRPGASQNTT 591
                       + P+ +       P   G      T     T + P   P        T 
Sbjct: 3842 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3901

Query: 592  FLTSGSILRQLIPTGKQVNGIPTYTLAPVSVTLPVPPGGLATVAPPQMPI 641
              T+ ++     PTG Q    PT T    + T+   P    T  P   PI
Sbjct: 3902 ITTTTTVTPTPTPTGTQT---PTTTPITTTTTVTPTPTPTGTQTPTTTPI 3948



 Score = 49.3 bits (116), Expect = 2e-05
 Identities = 83/410 (20%), Positives = 127/410 (30%), Gaps = 42/410 (10%)

Query: 258  TGLLKQTHIAPKPAAHLAAPANGSAPSAPAQPPCFHLALPQNSPSPAAGQ-PVTVAQGAP 316
            T +   T + P P          +    P   P         +P+P   Q P T      
Sbjct: 3578 TPITTTTTVTPTPTP--------TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 3629

Query: 317  GSLTHSPPAAGQ---------SHMTLVSSPLPVGQNSLTLQP--------PAPQPVFLSH 359
             ++T +P   G          +  T+  +P P G  + T  P        P P P     
Sbjct: 3630 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 3689

Query: 360  GVPLHQSVNPPVLPLSQPVGPVNKSVGTSVLPINQTVRPGVLPLTQPVGPINRPVGPGVL 419
                  +    V P   P G   ++  T+ +    TV P   P T    P   P+     
Sbjct: 3690 PTTTPITTTTTVTPTPTPTG--TQTPTTTPITTTTTVTPTPTP-TGTQTPTTTPITT-TT 3745

Query: 420  PVSPSVTPGVLQAVSPGVLSVSRAVPSGVLPAGQMTPAGQ--MTPAGVIPGQTATSGVLP 477
             V+P+ TP   Q  +   ++ +  V     P G  TP      T   V P  T T    P
Sbjct: 3746 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 3805

Query: 478  TGQMVQSGVLPVGQTAPSRVLPPGQTAPLRVISA--GQVVPSGLLSPNQT-VSSSAVVPV 534
            T   + +         P+    P  T P+   +       P+G  +P  T ++++  V  
Sbjct: 3806 TTTPITTTTTVTPTPTPTGTQTP-TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3864

Query: 535  NQGVNSGVLQLSQPVVSGVLPVGQPVRPGVLQLNQT---VGTNILPVNQPVRPGASQNTT 591
                       + P+ +       P   G      T     T + P   P        T 
Sbjct: 3865 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3924

Query: 592  FLTSGSILRQLIPTGKQVNGIPTYTLAPVSVTLPVPPGGLATVAPPQMPI 641
              T+ ++     PTG Q    PT T    + T+   P    T  P   PI
Sbjct: 3925 ITTTTTVTPTPTPTGTQT---PTTTPITTTTTVTPTPTPTGTQTPTTTPI 3971



 Score = 49.3 bits (116), Expect = 2e-05
 Identities = 83/410 (20%), Positives = 127/410 (30%), Gaps = 42/410 (10%)

Query: 258  TGLLKQTHIAPKPAAHLAAPANGSAPSAPAQPPCFHLALPQNSPSPAAGQ-PVTVAQGAP 316
            T +   T + P P          +    P   P         +P+P   Q P T      
Sbjct: 3601 TPITTTTTVTPTPTP--------TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 3652

Query: 317  GSLTHSPPAAGQ---------SHMTLVSSPLPVGQNSLTLQP--------PAPQPVFLSH 359
             ++T +P   G          +  T+  +P P G  + T  P        P P P     
Sbjct: 3653 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 3712

Query: 360  GVPLHQSVNPPVLPLSQPVGPVNKSVGTSVLPINQTVRPGVLPLTQPVGPINRPVGPGVL 419
                  +    V P   P G   ++  T+ +    TV P   P T    P   P+     
Sbjct: 3713 PTTTPITTTTTVTPTPTPTG--TQTPTTTPITTTTTVTPTPTP-TGTQTPTTTPITT-TT 3768

Query: 420  PVSPSVTPGVLQAVSPGVLSVSRAVPSGVLPAGQMTPAGQ--MTPAGVIPGQTATSGVLP 477
             V+P+ TP   Q  +   ++ +  V     P G  TP      T   V P  T T    P
Sbjct: 3769 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 3828

Query: 478  TGQMVQSGVLPVGQTAPSRVLPPGQTAPLRVISA--GQVVPSGLLSPNQT-VSSSAVVPV 534
            T   + +         P+    P  T P+   +       P+G  +P  T ++++  V  
Sbjct: 3829 TTTPITTTTTVTPTPTPTGTQTP-TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3887

Query: 535  NQGVNSGVLQLSQPVVSGVLPVGQPVRPGVLQLNQT---VGTNILPVNQPVRPGASQNTT 591
                       + P+ +       P   G      T     T + P   P        T 
Sbjct: 3888 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3947

Query: 592  FLTSGSILRQLIPTGKQVNGIPTYTLAPVSVTLPVPPGGLATVAPPQMPI 641
              T+ ++     PTG Q    PT T    + T+   P    T  P   PI
Sbjct: 3948 ITTTTTVTPTPTPTGTQT---PTTTPITTTTTVTPTPTPTGTQTPTTTPI 3994



 Score = 49.3 bits (116), Expect = 2e-05
 Identities = 83/410 (20%), Positives = 127/410 (30%), Gaps = 42/410 (10%)

Query: 258  TGLLKQTHIAPKPAAHLAAPANGSAPSAPAQPPCFHLALPQNSPSPAAGQ-PVTVAQGAP 316
            T +   T + P P          +    P   P         +P+P   Q P T      
Sbjct: 3624 TPITTTTTVTPTPTP--------TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 3675

Query: 317  GSLTHSPPAAGQ---------SHMTLVSSPLPVGQNSLTLQP--------PAPQPVFLSH 359
             ++T +P   G          +  T+  +P P G  + T  P        P P P     
Sbjct: 3676 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 3735

Query: 360  GVPLHQSVNPPVLPLSQPVGPVNKSVGTSVLPINQTVRPGVLPLTQPVGPINRPVGPGVL 419
                  +    V P   P G   ++  T+ +    TV P   P T    P   P+     
Sbjct: 3736 PTTTPITTTTTVTPTPTPTG--TQTPTTTPITTTTTVTPTPTP-TGTQTPTTTPITT-TT 3791

Query: 420  PVSPSVTPGVLQAVSPGVLSVSRAVPSGVLPAGQMTPAGQ--MTPAGVIPGQTATSGVLP 477
             V+P+ TP   Q  +   ++ +  V     P G  TP      T   V P  T T    P
Sbjct: 3792 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 3851

Query: 478  TGQMVQSGVLPVGQTAPSRVLPPGQTAPLRVISA--GQVVPSGLLSPNQT-VSSSAVVPV 534
            T   + +         P+    P  T P+   +       P+G  +P  T ++++  V  
Sbjct: 3852 TTTPITTTTTVTPTPTPTGTQTP-TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3910

Query: 535  NQGVNSGVLQLSQPVVSGVLPVGQPVRPGVLQLNQT---VGTNILPVNQPVRPGASQNTT 591
                       + P+ +       P   G      T     T + P   P        T 
Sbjct: 3911 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3970

Query: 592  FLTSGSILRQLIPTGKQVNGIPTYTLAPVSVTLPVPPGGLATVAPPQMPI 641
              T+ ++     PTG Q    PT T    + T+   P    T  P   PI
Sbjct: 3971 ITTTTTVTPTPTPTGTQT---PTTTPITTTTTVTPTPTPTGTQTPTTTPI 4017



 Score = 49.3 bits (116), Expect = 2e-05
 Identities = 83/410 (20%), Positives = 127/410 (30%), Gaps = 42/410 (10%)

Query: 258  TGLLKQTHIAPKPAAHLAAPANGSAPSAPAQPPCFHLALPQNSPSPAAGQ-PVTVAQGAP 316
            T +   T + P P          +    P   P         +P+P   Q P T      
Sbjct: 3647 TPITTTTTVTPTPTP--------TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 3698

Query: 317  GSLTHSPPAAGQ---------SHMTLVSSPLPVGQNSLTLQP--------PAPQPVFLSH 359
             ++T +P   G          +  T+  +P P G  + T  P        P P P     
Sbjct: 3699 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 3758

Query: 360  GVPLHQSVNPPVLPLSQPVGPVNKSVGTSVLPINQTVRPGVLPLTQPVGPINRPVGPGVL 419
                  +    V P   P G   ++  T+ +    TV P   P T    P   P+     
Sbjct: 3759 PTTTPITTTTTVTPTPTPTG--TQTPTTTPITTTTTVTPTPTP-TGTQTPTTTPITT-TT 3814

Query: 420  PVSPSVTPGVLQAVSPGVLSVSRAVPSGVLPAGQMTPAGQ--MTPAGVIPGQTATSGVLP 477
             V+P+ TP   Q  +   ++ +  V     P G  TP      T   V P  T T    P
Sbjct: 3815 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 3874

Query: 478  TGQMVQSGVLPVGQTAPSRVLPPGQTAPLRVISA--GQVVPSGLLSPNQT-VSSSAVVPV 534
            T   + +         P+    P  T P+   +       P+G  +P  T ++++  V  
Sbjct: 3875 TTTPITTTTTVTPTPTPTGTQTP-TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3933

Query: 535  NQGVNSGVLQLSQPVVSGVLPVGQPVRPGVLQLNQT---VGTNILPVNQPVRPGASQNTT 591
                       + P+ +       P   G      T     T + P   P        T 
Sbjct: 3934 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3993

Query: 592  FLTSGSILRQLIPTGKQVNGIPTYTLAPVSVTLPVPPGGLATVAPPQMPI 641
              T+ ++     PTG Q    PT T    + T+   P    T  P   PI
Sbjct: 3994 ITTTTTVTPTPTPTGTQT---PTTTPITTTTTVTPTPTPTGTQTPTTTPI 4040



 Score = 49.3 bits (116), Expect = 2e-05
 Identities = 83/410 (20%), Positives = 127/410 (30%), Gaps = 42/410 (10%)

Query: 258  TGLLKQTHIAPKPAAHLAAPANGSAPSAPAQPPCFHLALPQNSPSPAAGQ-PVTVAQGAP 316
            T +   T + P P          +    P   P         +P+P   Q P T      
Sbjct: 3670 TPITTTTTVTPTPTP--------TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 3721

Query: 317  GSLTHSPPAAGQ---------SHMTLVSSPLPVGQNSLTLQP--------PAPQPVFLSH 359
             ++T +P   G          +  T+  +P P G  + T  P        P P P     
Sbjct: 3722 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 3781

Query: 360  GVPLHQSVNPPVLPLSQPVGPVNKSVGTSVLPINQTVRPGVLPLTQPVGPINRPVGPGVL 419
                  +    V P   P G   ++  T+ +    TV P   P T    P   P+     
Sbjct: 3782 PTTTPITTTTTVTPTPTPTG--TQTPTTTPITTTTTVTPTPTP-TGTQTPTTTPITT-TT 3837

Query: 420  PVSPSVTPGVLQAVSPGVLSVSRAVPSGVLPAGQMTPAGQ--MTPAGVIPGQTATSGVLP 477
             V+P+ TP   Q  +   ++ +  V     P G  TP      T   V P  T T    P
Sbjct: 3838 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 3897

Query: 478  TGQMVQSGVLPVGQTAPSRVLPPGQTAPLRVISA--GQVVPSGLLSPNQT-VSSSAVVPV 534
            T   + +         P+    P  T P+   +       P+G  +P  T ++++  V  
Sbjct: 3898 TTTPITTTTTVTPTPTPTGTQTP-TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3956

Query: 535  NQGVNSGVLQLSQPVVSGVLPVGQPVRPGVLQLNQT---VGTNILPVNQPVRPGASQNTT 591
                       + P+ +       P   G      T     T + P   P        T 
Sbjct: 3957 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 4016

Query: 592  FLTSGSILRQLIPTGKQVNGIPTYTLAPVSVTLPVPPGGLATVAPPQMPI 641
              T+ ++     PTG Q    PT T    + T+   P    T  P   PI
Sbjct: 4017 ITTTTTVTPTPTPTGTQT---PTTTPITTTTTVTPTPTPTGTQTPTTTPI 4063



 Score = 49.3 bits (116), Expect = 2e-05
 Identities = 83/410 (20%), Positives = 127/410 (30%), Gaps = 42/410 (10%)

Query: 258  TGLLKQTHIAPKPAAHLAAPANGSAPSAPAQPPCFHLALPQNSPSPAAGQ-PVTVAQGAP 316
            T +   T + P P          +    P   P         +P+P   Q P T      
Sbjct: 3693 TPITTTTTVTPTPTP--------TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 3744

Query: 317  GSLTHSPPAAGQ---------SHMTLVSSPLPVGQNSLTLQP--------PAPQPVFLSH 359
             ++T +P   G          +  T+  +P P G  + T  P        P P P     
Sbjct: 3745 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 3804

Query: 360  GVPLHQSVNPPVLPLSQPVGPVNKSVGTSVLPINQTVRPGVLPLTQPVGPINRPVGPGVL 419
                  +    V P   P G   ++  T+ +    TV P   P T    P   P+     
Sbjct: 3805 PTTTPITTTTTVTPTPTPTG--TQTPTTTPITTTTTVTPTPTP-TGTQTPTTTPITT-TT 3860

Query: 420  PVSPSVTPGVLQAVSPGVLSVSRAVPSGVLPAGQMTPAGQ--MTPAGVIPGQTATSGVLP 477
             V+P+ TP   Q  +   ++ +  V     P G  TP      T   V P  T T    P
Sbjct: 3861 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 3920

Query: 478  TGQMVQSGVLPVGQTAPSRVLPPGQTAPLRVISA--GQVVPSGLLSPNQT-VSSSAVVPV 534
            T   + +         P+    P  T P+   +       P+G  +P  T ++++  V  
Sbjct: 3921 TTTPITTTTTVTPTPTPTGTQTP-TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3979

Query: 535  NQGVNSGVLQLSQPVVSGVLPVGQPVRPGVLQLNQT---VGTNILPVNQPVRPGASQNTT 591
                       + P+ +       P   G      T     T + P   P        T 
Sbjct: 3980 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 4039

Query: 592  FLTSGSILRQLIPTGKQVNGIPTYTLAPVSVTLPVPPGGLATVAPPQMPI 641
              T+ ++     PTG Q    PT T    + T+   P    T  P   PI
Sbjct: 4040 ITTTTTVTPTPTPTGTQT---PTTTPITTTTTVTPTPTPTGTQTPTTTPI 4086



 Score = 49.3 bits (116), Expect = 2e-05
 Identities = 83/410 (20%), Positives = 127/410 (30%), Gaps = 42/410 (10%)

Query: 258  TGLLKQTHIAPKPAAHLAAPANGSAPSAPAQPPCFHLALPQNSPSPAAGQ-PVTVAQGAP 316
            T +   T + P P          +    P   P         +P+P   Q P T      
Sbjct: 3716 TPITTTTTVTPTPTP--------TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 3767

Query: 317  GSLTHSPPAAGQ---------SHMTLVSSPLPVGQNSLTLQP--------PAPQPVFLSH 359
             ++T +P   G          +  T+  +P P G  + T  P        P P P     
Sbjct: 3768 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 3827

Query: 360  GVPLHQSVNPPVLPLSQPVGPVNKSVGTSVLPINQTVRPGVLPLTQPVGPINRPVGPGVL 419
                  +    V P   P G   ++  T+ +    TV P   P T    P   P+     
Sbjct: 3828 PTTTPITTTTTVTPTPTPTG--TQTPTTTPITTTTTVTPTPTP-TGTQTPTTTPITT-TT 3883

Query: 420  PVSPSVTPGVLQAVSPGVLSVSRAVPSGVLPAGQMTPAGQ--MTPAGVIPGQTATSGVLP 477
             V+P+ TP   Q  +   ++ +  V     P G  TP      T   V P  T T    P
Sbjct: 3884 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 3943

Query: 478  TGQMVQSGVLPVGQTAPSRVLPPGQTAPLRVISA--GQVVPSGLLSPNQT-VSSSAVVPV 534
            T   + +         P+    P  T P+   +       P+G  +P  T ++++  V  
Sbjct: 3944 TTTPITTTTTVTPTPTPTGTQTP-TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 4002

Query: 535  NQGVNSGVLQLSQPVVSGVLPVGQPVRPGVLQLNQT---VGTNILPVNQPVRPGASQNTT 591
                       + P+ +       P   G      T     T + P   P        T 
Sbjct: 4003 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 4062

Query: 592  FLTSGSILRQLIPTGKQVNGIPTYTLAPVSVTLPVPPGGLATVAPPQMPI 641
              T+ ++     PTG Q    PT T    + T+   P    T  P   PI
Sbjct: 4063 ITTTTTVTPTPTPTGTQT---PTTTPITTTTTVTPTPTPTGTQTPTTTPI 4109



 Score = 49.3 bits (116), Expect = 2e-05
 Identities = 83/410 (20%), Positives = 127/410 (30%), Gaps = 42/410 (10%)

Query: 258  TGLLKQTHIAPKPAAHLAAPANGSAPSAPAQPPCFHLALPQNSPSPAAGQ-PVTVAQGAP 316
            T +   T + P P          +    P   P         +P+P   Q P T      
Sbjct: 3739 TPITTTTTVTPTPTP--------TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 3790

Query: 317  GSLTHSPPAAGQ---------SHMTLVSSPLPVGQNSLTLQP--------PAPQPVFLSH 359
             ++T +P   G          +  T+  +P P G  + T  P        P P P     
Sbjct: 3791 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 3850

Query: 360  GVPLHQSVNPPVLPLSQPVGPVNKSVGTSVLPINQTVRPGVLPLTQPVGPINRPVGPGVL 419
                  +    V P   P G   ++  T+ +    TV P   P T    P   P+     
Sbjct: 3851 PTTTPITTTTTVTPTPTPTG--TQTPTTTPITTTTTVTPTPTP-TGTQTPTTTPITT-TT 3906

Query: 420  PVSPSVTPGVLQAVSPGVLSVSRAVPSGVLPAGQMTPAGQ--MTPAGVIPGQTATSGVLP 477
             V+P+ TP   Q  +   ++ +  V     P G  TP      T   V P  T T    P
Sbjct: 3907 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 3966

Query: 478  TGQMVQSGVLPVGQTAPSRVLPPGQTAPLRVISA--GQVVPSGLLSPNQT-VSSSAVVPV 534
            T   + +         P+    P  T P+   +       P+G  +P  T ++++  V  
Sbjct: 3967 TTTPITTTTTVTPTPTPTGTQTP-TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 4025

Query: 535  NQGVNSGVLQLSQPVVSGVLPVGQPVRPGVLQLNQT---VGTNILPVNQPVRPGASQNTT 591
                       + P+ +       P   G      T     T + P   P        T 
Sbjct: 4026 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 4085

Query: 592  FLTSGSILRQLIPTGKQVNGIPTYTLAPVSVTLPVPPGGLATVAPPQMPI 641
              T+ ++     PTG Q    PT T    + T+   P    T  P   PI
Sbjct: 4086 ITTTTTVTPTPTPTGTQT---PTTTPITTTTTVTPTPTPTGTQTPTTTPI 4132



 Score = 49.3 bits (116), Expect = 2e-05
 Identities = 83/410 (20%), Positives = 127/410 (30%), Gaps = 42/410 (10%)

Query: 258  TGLLKQTHIAPKPAAHLAAPANGSAPSAPAQPPCFHLALPQNSPSPAAGQ-PVTVAQGAP 316
            T +   T + P P          +    P   P         +P+P   Q P T      
Sbjct: 3762 TPITTTTTVTPTPTP--------TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 3813

Query: 317  GSLTHSPPAAGQ---------SHMTLVSSPLPVGQNSLTLQP--------PAPQPVFLSH 359
             ++T +P   G          +  T+  +P P G  + T  P        P P P     
Sbjct: 3814 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 3873

Query: 360  GVPLHQSVNPPVLPLSQPVGPVNKSVGTSVLPINQTVRPGVLPLTQPVGPINRPVGPGVL 419
                  +    V P   P G   ++  T+ +    TV P   P T    P   P+     
Sbjct: 3874 PTTTPITTTTTVTPTPTPTG--TQTPTTTPITTTTTVTPTPTP-TGTQTPTTTPITT-TT 3929

Query: 420  PVSPSVTPGVLQAVSPGVLSVSRAVPSGVLPAGQMTPAGQ--MTPAGVIPGQTATSGVLP 477
             V+P+ TP   Q  +   ++ +  V     P G  TP      T   V P  T T    P
Sbjct: 3930 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 3989

Query: 478  TGQMVQSGVLPVGQTAPSRVLPPGQTAPLRVISA--GQVVPSGLLSPNQT-VSSSAVVPV 534
            T   + +         P+    P  T P+   +       P+G  +P  T ++++  V  
Sbjct: 3990 TTTPITTTTTVTPTPTPTGTQTP-TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 4048

Query: 535  NQGVNSGVLQLSQPVVSGVLPVGQPVRPGVLQLNQT---VGTNILPVNQPVRPGASQNTT 591
                       + P+ +       P   G      T     T + P   P        T 
Sbjct: 4049 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 4108

Query: 592  FLTSGSILRQLIPTGKQVNGIPTYTLAPVSVTLPVPPGGLATVAPPQMPI 641
              T+ ++     PTG Q    PT T    + T+   P    T  P   PI
Sbjct: 4109 ITTTTTVTPTPTPTGTQT---PTTTPITTTTTVTPTPTPTGTQTPTTTPI 4155



 Score = 47.8 bits (112), Expect = 6e-05
 Identities = 83/399 (20%), Positives = 129/399 (32%), Gaps = 42/399 (10%)

Query: 258  TGLLKQTHIAPKPAAHLAAPANGSAPSAPAQPPCFHLALPQNSPSPAAGQ-PVTVAQGAP 316
            T +   T + P P          +    P   P         +P+P   Q P T      
Sbjct: 3831 TPITTTTTVTPTPTP--------TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 3882

Query: 317  GSLTHSPPAAGQ---------SHMTLVSSPLPVGQNSLTLQP--------PAPQPVFLSH 359
             ++T +P   G          +  T+  +P P G  + T  P        P P P     
Sbjct: 3883 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 3942

Query: 360  GVPLHQSVNPPVLPLSQPVGPVNKSVGTSVLPINQTVRPGVLPLTQPVGPINRPVGPGVL 419
                  +    V P   P G   ++  T+ +    TV P   P T    P   P+     
Sbjct: 3943 PTTTPITTTTTVTPTPTPTG--TQTPTTTPITTTTTVTPTPTP-TGTQTPTTTPITT-TT 3998

Query: 420  PVSPSVTPGVLQAVSPGVLSVSRAVPSGVLPAGQMTPAGQ--MTPAGVIPGQTATSGVLP 477
             V+P+ TP   Q  +   ++ +  V     P G  TP      T   V P  T T    P
Sbjct: 3999 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 4058

Query: 478  TGQMVQSGVLPVGQTAPSRVLPPGQTAPLRVISA--GQVVPSGLLSPNQT-VSSSAVVPV 534
            T   + +         P+    P  T P+   +       P+G  +P  T ++++  V  
Sbjct: 4059 TTTPITTTTTVTPTPTPTGTQTP-TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 4117

Query: 535  NQGVNSGVLQLSQPVVSGVLPVGQPVRPGVLQLNQT---VGTNILPVNQPVRPGASQNTT 591
                       + P+ +       P   G      T     T + P   P        T 
Sbjct: 4118 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 4177

Query: 592  FLTSGSILRQLIPTGKQVNGIPTYT-LAPVS-VTLPVPP 628
              T+ ++     PTG Q  G PT+T  AP++ +T   PP
Sbjct: 4178 ITTTTTVTPTPTPTGTQ-TGPPTHTSTAPIAELTTSNPP 4215



 Score = 47.4 bits (111), Expect = 8e-05
 Identities = 71/344 (20%), Positives = 111/344 (32%), Gaps = 33/344 (9%)

Query: 307  QPVTVAQGAPGSLTHSPPAAGQSHMTLVSSPLPVGQNSLTLQP--------PAPQPVFLS 358
            QP T+      + T        +  T+  +P P G  + T  P        P P P    
Sbjct: 1881 QPTTMTTTTTENPTPPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ 1940

Query: 359  HGVPLHQSVNPPVLPLSQPVGPVNKSVGTSVLPINQTVRPGVLPLTQPVGPINRPVGPGV 418
                   +    V P   P G   ++  T+ +    TV P   P T    P   P+    
Sbjct: 1941 TPTTTPITTTTTVTPTPTPTG--TQTPTTTPITTTTTVTPTPTP-TGTQTPTTTPITT-T 1996

Query: 419  LPVSPSVTPGVLQAVSPGVLSVSRAVPSGVLPAGQMTPAGQMTPAGVIPGQTATSGVLPT 478
              V+P+ TP   Q  +   ++ +  V     P G  TP    T   +    T T    PT
Sbjct: 1997 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP----TTTPITTTTTVTPTPTPT 2052

Query: 479  GQMVQSGVLPVGQTAPSRVLPPGQTAPLRVISAGQVVPSGLLSPNQTVSSSAVVPVNQGV 538
            G    +   P+  T  + V P       +  +   +  +  ++P  T + +   P    +
Sbjct: 2053 GTQTPT-TTPI--TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-PTTTPI 2108

Query: 539  NSGVLQLSQPVVSGV-LPVGQPVRPGVLQLNQTVGTNILPVNQPVRPGASQNTTFLTSGS 597
             +       P  +G   P   P+         T  T + P   P        T   T+ +
Sbjct: 2109 TTTTTVTPTPTPTGTQTPTTTPI---------TTTTTVTPTPTPTGTQTPTTTPITTTTT 2159

Query: 598  ILRQLIPTGKQVNGIPTYTLAPVSVTLPVPPGGLATVAPPQMPI 641
            +     PTG Q    PT T    + T+   P    T  P   PI
Sbjct: 2160 VTPTPTPTGTQT---PTTTPITTTTTVTPTPTPTGTQTPTTTPI 2200



 Score = 43.9 bits (102), Expect = 9e-04
 Identities = 77/359 (21%), Positives = 112/359 (31%), Gaps = 49/359 (13%)

Query: 258  TGLLKQTHIAPKPAAHLAAPANGSAPSAPAQPPCFHLALPQNSPSPAAGQ-PVTVAQGAP 316
            T +   T + P P          +    P   P         +P+P   Q P T      
Sbjct: 3969 TPITTTTTVTPTPTP--------TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 4020

Query: 317  GSLTHSPPAAGQ---------SHMTLVSSPLPVGQNSLTLQP--------PAPQPVFLSH 359
             ++T +P   G          +  T+  +P P G  + T  P        P P P     
Sbjct: 4021 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 4080

Query: 360  GVPLHQSVNPPVLPLSQPVGPVNKSVGTSVLPINQTVRPGVLPLTQPVGPINRPVGPGVL 419
                  +    V P   P G   ++  T+ +    TV P   P T    P   P+     
Sbjct: 4081 PTTTPITTTTTVTPTPTPTG--TQTPTTTPITTTTTVTPTPTP-TGTQTPTTTPITT-TT 4136

Query: 420  PVSPSVTPGVLQAVSPGVLSVSRAVPSGVLPAGQMTPAGQMTPAGVIPGQTATSGVLPTG 479
             V+P+ TP   Q  +   ++ +  V     P G  TP             T T     TG
Sbjct: 4137 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTG 4196

Query: 480  QMVQSGVLPVGQTAPSRVLPPGQTAP--LRVISAGQVVPSGLLSP-----NQTVSSSAVV 532
                +   P+ +   S   PP  + P   R  S+     + LLS        T ++    
Sbjct: 4197 PPTHTSTAPIAELTTSNP-PPESSTPQTSRSTSSPLTESTTLLSTLPPAIEMTSTAPPST 4255

Query: 533  PVNQGVNSGVLQLSQPVVSGVLPVGQPVRPGVLQLNQTVGTNILPVNQPVRPGASQNTT 591
            P      SG   LS P  +   P G P R        T G++  P      P   Q TT
Sbjct: 4256 PTAPTTTSGGHTLSPPPSTTTSPPGTPTR------GTTTGSSSAPT-----PSTVQTTT 4303



 Score = 36.6 bits (83), Expect = 0.14
 Identities = 60/300 (20%), Positives = 89/300 (29%), Gaps = 68/300 (22%)

Query: 362  PLHQSVNPPVLPLSQPVGPVNKSVGTSVLPINQTVRPGVLPLTQPVGPINRPVGPGVLPV 421
            P+ + +  P  P + P  P      T+ LP   T  P     T P  P      P   P+
Sbjct: 1391 PMDKCITTPSPPTTTPSPP---PTSTTTLPPTTTPSPPTTTTTTP--PPTTTPSP---PI 1442

Query: 422  SPSVTPGVLQAVSPGVLSVSRAVPSGVLPAGQMTPAGQMTPAGVIPGQTATSGVLPTGQM 481
            + + TP      SP + + +   P+        TP+   T     P  T T+   PT   
Sbjct: 1443 TTTTTPPPTTTPSPPISTTTTPPPTTTPSPPTTTPSPPTTTPS--PPTTTTTTPPPTTTP 1500

Query: 482  VQSGVLPVGQTAPSRVLPPGQTAPLRVISAGQVVPSGLLSPNQTVSSSAVVPVNQGVNSG 541
                  P+   A +  LPP  T                  P+   +++   P        
Sbjct: 1501 SPPTTTPITPPASTTTLPPTTT------------------PSPPTTTTTTPP-------- 1534

Query: 542  VLQLSQPVVSGVLPVGQPVRPGVLQLNQTVGTNILPVNQPVRPGASQNTTFLTSGSILRQ 601
                  P  +   P   P+ P       T  T + P   P  P  +  T           
Sbjct: 1535 ------PTTTPSPPTTTPITP------PTSTTTLPPTTTPSPPPTTTTTP---------- 1572

Query: 602  LIPTGKQVNGIPTYTLAPVSVTLPVPPGGLATVAPPQMPIQLLPSGAAAPMAGSMPGMPS 661
                       PT T +P + T P PP    T  PP        +    P   + P  P+
Sbjct: 1573 ----------PPTTTPSPPTTTTPSPPTITTTTPPPTTTPSPPTTTTTTPPPTTTPSPPT 1622


>gi|163914392 glioma tumor suppressor candidate region gene 1 [Homo
           sapiens]
          Length = 1560

 Score = 58.2 bits (139), Expect = 4e-08
 Identities = 115/477 (24%), Positives = 172/477 (36%), Gaps = 104/477 (21%)

Query: 276 APANGSAPSAPAQPPCFHLALPQNSPSPA-----------------AGQPVTVAQGAPGS 318
           AP  GS+P  PA     H       P PA                 AG  +T+ QG PG+
Sbjct: 328 APGLGSSPLVPAPNVILHRTPTPIQPKPAGVLPPKLYQLTPKPFAPAGATLTI-QGEPGA 386

Query: 319 LTHSPP--------AAGQSHMTLVSS--PLPVGQNSLTLQPPA-------PQPV-FLSHG 360
           L   P         AAG++   +V S  P P  Q ++  QPPA       PQP   LS  
Sbjct: 387 LPQQPKAPQNLTFMAAGKAGQNVVLSGFPAPALQANVFKQPPATTTGAAPPQPPGALSKP 446

Query: 361 VPLH------------QSVNP----------PVLPLSQPVGPVNKSVGTSVLPI------ 392
           + +H            Q + P          P + L Q +  +  +VG  +L        
Sbjct: 447 MSVHLLNQGSSIVIPAQHMLPGQNQFLLPGAPAVQLPQQLSALPANVGGQILAAAAPHTG 506

Query: 393 NQTVRPGVLPLTQPVGPINRPVGPGVLPVSPSVTPGVLQAV-----SPGVLSVSRAVPSG 447
            Q +   +L      GP++  +GP + P S + +  +L A       P +  +  ++ +G
Sbjct: 507 GQLIANPILTNQNLAGPLS--LGPVLAPHSGAHSAHILSAAPIQVGQPALFQMPVSLAAG 564

Query: 448 VLPA-GQMTPAG----------QMTPAGVIPGQTATSGVLPTGQMVQSG-VLPVGQTAPS 495
            LP   Q  PAG           + P+ V    T    V P      +G   PV    P+
Sbjct: 565 SLPTQSQPAPAGPAATTVLQGVTLPPSAVAMLNTPDGLVQPATPAAATGEAAPVLTVQPA 624

Query: 496 RVLPPGQTAPLRVISAGQVVPSGLLSPNQTVSSSAVVP--VNQGVNSGVLQLSQPVVSGV 553
              PP  + PL +   G   P     P      +A  P       + G+    + +V G 
Sbjct: 625 PQAPPAVSTPLPL---GLQQPQAQQPPQAPTPQAAAPPQATTPQPSPGLASSPEKIVLGQ 681

Query: 554 LPVGQPVRPGVLQLNQTVGTNILPVNQPVRPGASQNTTFLTSGSILRQLIPTGKQVNGIP 613
            P   P       L Q      LP  +  +P +++        S++    P  +  +  P
Sbjct: 682 PPSATP----TAILTQDSLQMFLPQERSQQPLSAEGPHLSVPASVIVSAPPPAQ--DPAP 735

Query: 614 TYTLAPVSVTLPVPPGGLATVAP-PQMPIQLLPSGAAAPMAGSMPGMPSPPVLVNAA 669
              +A  +   P  P   A+ AP PQ+P       AAAP+ G  PG  S P L + A
Sbjct: 736 ATPVAKGAGLGPQAPDSQASPAPAPQIP-------AAAPLKG--PGPSSSPSLPHQA 783



 Score = 52.4 bits (124), Expect = 2e-06
 Identities = 89/377 (23%), Positives = 124/377 (32%), Gaps = 76/377 (20%)

Query: 263  QTHIAPKPAAHLAAPANGSAPSA-PAQPPCFHLALPQNSPSPAAGQPVTVAQGAPGSLTH 321
            Q   AP P    AAP  G  PS+ P+ P    L    + PSP   +P +     P S++ 
Sbjct: 753  QASPAPAPQIPAAAPLKGPGPSSSPSLPHQAPLGDSPHLPSPHPTRPPSRPPSRPQSVSR 812

Query: 322  SPPAAGQSHMTLVSSPLP------VGQNSLTLQPPAPQPVFLSHGVPLHQSVNPPVLPLS 375
             PP+    H        P      V QN L + PPA  P   + G P      PP+ P S
Sbjct: 813  -PPSEPPLHPCPPPQAPPTLPGIFVIQNQLGVPPPASNPAPTAPGPP-----QPPLRPQS 866

Query: 376  QPV-GPVNKSVGTSVLPINQTVRPGVLPLTQPVGPINRPVGPGVLPVSPSVTPGVLQAVS 434
            QP  GP+                        P  P   P        S S T   L A +
Sbjct: 867  QPPEGPL------------------------PPAPHLPPSSTSSAVASSSETSSRLPAPT 902

Query: 435  PGVLSVSRAVPSGVLPAGQMTPAGQMTPAGVIPGQTATSGVLPTGQMVQSGVLPVGQTAP 494
            P    +      G   +    P   + P    P          T QMV         T P
Sbjct: 903  PSDFQLQFPPSQGPHKSPTPPPTLHLVPEPAAPPPPPPR----TFQMV---------TTP 949

Query: 495  SRVLPPGQTAPLRVISAGQVVPSGLLSPNQTVSSSAVVPVNQGVNSGVLQLSQPVVSGVL 554
               LP     P  ++     VPSG++  N+   + A    +  +       +  +VSG  
Sbjct: 950  FPALPQ----PKALLERFHQVPSGIILQNKAGGAPAAPQTSTSLGPLTSPAASVLVSGQA 1005

Query: 555  PVGQPVRPGVLQLNQTVGTNILPVNQPVRPGASQNTTFLTSGSILRQLIPTGKQVNGIPT 614
            P G P  P        +    LP   P+ P  ++N  F                 + +PT
Sbjct: 1006 PSGTPTAPSHAPAPAPMAATGLP---PLLP--AENKAF----------------ASNLPT 1044

Query: 615  YTLAPVSVTLPVPPGGL 631
              +A  + + P  P GL
Sbjct: 1045 LNVAKAASSGPGKPSGL 1061



 Score = 45.8 bits (107), Expect = 2e-04
 Identities = 98/396 (24%), Positives = 143/396 (36%), Gaps = 48/396 (12%)

Query: 339 PVGQNSLTLQPPAPQPVFLSHGVPLHQSVNPPVLP---LSQPVGPVNKSVGTSVLPINQT 395
           P G          PQ +F      L     P VL    L  P   VNK++  SV P  Q 
Sbjct: 143 PTGAGGAAAVAAGPQALFPGSTDLLGLQGPPTVLTHQALVPPQDVVNKAL--SVQPFLQP 200

Query: 396 VRPGVLPLTQPVGPINRPVGPGVLPVSPSVTPGVLQAVSPGVLSVSRAVPSGVLPAGQMT 455
           V  G + L    G    P G      + ++    +Q V   V++++   P+  L A Q+ 
Sbjct: 201 VGLGNVTLQPIPGLQGLPNGSPGGATAATLGLAPIQVVGQPVMALN--TPTSQLLAKQVP 258

Query: 456 PAGQMTPAG--VIPGQTATSGVLPTGQ--MVQSGV-LPVGQTAPSRVLPPGQTAPLRVIS 510
            +G +  A     P   A++GV P G   ++Q  +   V  T     +  G  A     S
Sbjct: 259 VSGYLASAAGPSEPVTLASAGVSPQGAGLVIQKNLSAAVATTLNGNSVFGGAGAA----S 314

Query: 511 AGQVVPSGL-LSPNQTVSSSAVVPVNQGVNSGVLQLSQPVVSGVLP------VGQPVRPG 563
           A    PSG  L+    + SS +VP    +        QP  +GVLP        +P  P 
Sbjct: 315 APTGTPSGQPLAVAPGLGSSPLVPAPNVILHRTPTPIQPKPAGVLPPKLYQLTPKPFAPA 374

Query: 564 VLQLNQTVGTNILPVNQPVRPGASQNTTFLTSGSILRQLIPTGKQVNGIPTYTLAPVSVT 623
                 T+     P   P +P A QN TF+ +G   + ++     ++G P   L   +  
Sbjct: 375 ----GATLTIQGEPGALPQQPKAPQNLTFMAAGKAGQNVV-----LSGFPAPALQ--ANV 423

Query: 624 LPVPPGGLATVAPPQMPIQLLPSGAAAPMAGSMPGMPSPPVLVNAAQSVFVQASSSAADT 683
              PP      APPQ      P GA +         P    L+N   S+ + A       
Sbjct: 424 FKQPPATTTGAAPPQ------PPGALSK--------PMSVHLLNQGSSIVIPAQHMLPGQ 469

Query: 684 NQVLKQAKQWKTCPVCNELFPSNVYQVHMEVAHKHS 719
           NQ L         P      P+NV    +  A  H+
Sbjct: 470 NQFLLPGAPAVQLPQQLSALPANVGGQILAAAAPHT 505


>gi|171460948 TSC22 domain family, member 1 isoform 1 [Homo sapiens]
          Length = 1073

 Score = 57.8 bits (138), Expect = 6e-08
 Identities = 94/363 (25%), Positives = 133/363 (36%), Gaps = 60/363 (16%)

Query: 264 THIAPKPAAHLAAP-ANGSAPS----APAQPPCFHLALPQNSPSPAAG----------QP 308
           T I P P   +    A G  PS    A  Q P    A P  +P P A           QP
Sbjct: 575 TGIQPSPVNVVGVTSALGQQPSISSLAQPQLPYSQAAPPVQTPLPGAPPPQQLQYGQQQP 634

Query: 309 VTVAQGAPG---SLTHSPPAAGQSHMTLVSSPLPVGQNSL------TLQPPAPQPVFLSH 359
           +   Q APG   S+T +P +       ++ + +  GQ S       T   P  QP     
Sbjct: 635 MVSTQMAPGHVKSVTQNPASEYVQQQPILQTAMSSGQPSSAGVGAGTTVIPVAQP----- 689

Query: 360 GVPLHQSVNPPVLPLSQPVGPVNKSVGTSVLPINQT-VRPGVLPLTQPVGPINRP--VGP 416
                Q +  PV P + P  P     G SV P+ Q       +P    +  I +   +  
Sbjct: 690 -----QGIQLPVQPTAVPAQPA----GASVQPVGQAPAAVSAVPTGSQIANIGQQANIPT 740

Query: 417 GVLPVSPSVTPGVLQAVSPGVLSVSRAVPSGVLPAGQMTPAGQMTPAGVIPGQTATSGVL 476
            V   S  V P V+Q  +P    V     +G++  G  T A  +    VI  Q++   V 
Sbjct: 741 AVQQPSTQVPPSVIQQGAPPSSQVVPPAQTGIIHQGVQTSAPSLPQQLVIASQSSLLTVP 800

Query: 477 PTGQMVQSGVLPVGQTAPSRVLPPGQTAP----LRVIS-AGQVVPSGLLS-PNQTVSSSA 530
           P  Q    GV PV Q   S+ LP   + P    + V S      PSG+ S P   V    
Sbjct: 801 PQPQ----GVEPVAQGIVSQQLPAVSSLPSASSISVTSQVSSTGPSGMPSAPTNLVPPQN 856

Query: 531 VVPVNQGVNSGVLQ-LSQPVVSGV---LPVGQPVRPGVLQ-----LNQTVGTNILPVNQP 581
           +       N  ++Q +SQP +      LP+ Q +     Q     L Q +G+ I    + 
Sbjct: 857 IAQTPATQNGNLVQSVSQPPLIATNTNLPLAQQIPLSSTQFSAQSLAQAIGSQIEDARRA 916

Query: 582 VRP 584
             P
Sbjct: 917 AEP 919


>gi|4508017 zinc finger protein 207 isoform a [Homo sapiens]
          Length = 478

 Score = 56.6 bits (135), Expect = 1e-07
 Identities = 86/311 (27%), Positives = 123/311 (39%), Gaps = 46/311 (14%)

Query: 382 NKSVGTSVLPINQTVRPG---VLPLTQP-VGPINRPVGPGVLPVSPSVTPGVLQAVSPGV 437
           + +  TS  P  Q V+P    + P+ QP + P+  P  PG+ P  P + PGV   + PG+
Sbjct: 120 DSAASTSFQP--QPVQPQQGYIPPMAQPGLPPV--PGAPGMPPGIPPLMPGV-PPLMPGM 174

Query: 438 LSVSRAVPSGVLPAGQMTPAGQMTP---AGVIPGQ---TATSGVLPTGQ---MVQSGVL- 487
             V   +P G++P G M P G   P    G+ PG        G+ P  Q   +   G+L 
Sbjct: 175 PPVMPGMPPGMMPMGGMMPPGPGIPPLMPGMPPGMPPPVPRPGIPPMTQAQAVSAPGILN 234

Query: 488 -PVGQTAPSRVLPPGQTAPLRVISAGQVVPSGLLSPNQTVSSSAVVPVNQGVNSGVLQLS 546
            P   TA      P  T PL   SAGQ+      S   + +S ++   ++ +     Q +
Sbjct: 235 RPPAPTATVPAPQPPVTKPL-FPSAGQMGTPVTSSSTASSNSESLSASSKALFPSTAQ-A 292

Query: 547 QPVVSGVLPVGQPVRPGVLQLNQTVGTNILPVNQPVRPGASQNTTFLTSGSILRQLIPTG 606
           Q  V G  PVG   +P    LN T  T   P  +P  P  +Q+T   TS +      P  
Sbjct: 293 QAAVQG--PVGTDFKP----LNSTPATTTEP-PKPTFPAYTQSTASTTSTTNSTAAKPAA 345

Query: 607 KQVNGIPTYTLAPVSVTLPVPPGGLA--------------TVAPPQMPIQLLPSGAAAPM 652
              +   T T    +  L  P   ++                 P Q PI   P G   P+
Sbjct: 346 SITSKPATLTTTSATSKLIHPDEDISLEERRAQLPKYQRNLPRPGQAPIGNPPVG---PI 402

Query: 653 AGSMPGMPSPP 663
            G MP  P  P
Sbjct: 403 GGMMPPQPGIP 413



 Score = 32.3 bits (72), Expect = 2.6
 Identities = 59/283 (20%), Positives = 85/283 (30%), Gaps = 66/283 (23%)

Query: 274 LAAPANGSAPSAPAQPPCFHLALPQNSPSPAAGQPVTVAQGAPGSLTHSPPAAGQSHMTL 333
           +A P     P AP  PP     +P   P         +  G P  +   PP         
Sbjct: 142 MAQPGLPPVPGAPGMPPGIPPLMPGVPP---------LMPGMPPVMPGMPPGM------- 185

Query: 334 VSSPLPVGQNSLTLQPPAPQPVFLSHGVPLHQSVNPPVLPLSQPVGPVNKSVGTSVLPIN 393
               +P+G     + PP P       G+P      PP +P   P                
Sbjct: 186 ----MPMG----GMMPPGP-------GIPPLMPGMPPGMPPPVP---------------- 214

Query: 394 QTVRPGVLPLTQ-----PVGPINRPVGPGVLPVSPSVTPGVLQAVSPGVLSVSRAVPSGV 448
              RPG+ P+TQ       G +NRP  P      P+  P V + + P    +   V S  
Sbjct: 215 ---RPGIPPMTQAQAVSAPGILNRP--PAPTATVPAPQPPVTKPLFPSAGQMGTPVTSSS 269

Query: 449 LPAGQMTPAGQMTPA---GVIPGQTATSGVLPTGQMVQSGVLPVGQTAPSRVLPPGQTAP 505
             +         + A        Q A  G  P G    +   P+  T  +   PP  T P
Sbjct: 270 TASSNSESLSASSKALFPSTAQAQAAVQG--PVG----TDFKPLNSTPATTTEPPKPTFP 323

Query: 506 LRVISAGQVVPSGLLSPNQTVSSSAVVPVNQGVNSGVLQLSQP 548
               S      +   +  +  +S    P      S   +L  P
Sbjct: 324 AYTQSTASTTSTTNSTAAKPAASITSKPATLTTTSATSKLIHP 366


>gi|150378545 POM121 membrane glycoprotein (rat)-like [Homo sapiens]
          Length = 987

 Score = 55.8 bits (133), Expect = 2e-07
 Identities = 87/372 (23%), Positives = 133/372 (35%), Gaps = 46/372 (12%)

Query: 343 NSLTLQPPAPQPVFLSHGVPLHQSVNPPVLPLSQPVGPVNKSVGTSVLPINQTVRPGVLP 402
           NS+T  PP  QP F +  +P   + +PP   L+    P+ +S+     P      P + P
Sbjct: 295 NSVTETPPTTQPSF-TFTLPAAATASPPTSLLAPSTNPLLESLKKMQTP------PSLPP 347

Query: 403 LTQPVG-----PINRPVGPGVLP---VSPSVTPGVLQAVSPGVLSVSRAVPSGVLPAGQM 454
             +  G      ++ P  P +LP   +S S  PG+L   SP   S       G++PA  M
Sbjct: 348 CPESAGAATTEALSPPKTPSLLPPLGLSQSGPPGLLP--SPSFDSKPPTTLLGLIPAPSM 405

Query: 455 TPAGQMTPAGVIPGQTAT---SGVLPTGQMVQSGVLPVGQTAPSRVLPPGQ--------- 502
            PA        +  +TAT   +   P+    QS +     T+PS    P           
Sbjct: 406 VPATDTKAPPTLQAETATKPQATSAPSPAPKQSFLFGTQNTSPSSPAAPAASSASPMFKP 465

Query: 503 --TAPLRVISAGQVVPSGLLSPNQTVSSSAVVPVNQGVNSGVLQLSQPVVSGVLPVGQPV 560
             TAP +    G   P    S   T  SS+ +P      +      QPV S + P     
Sbjct: 466 IFTAPPKSEKEGPTPPGP--SVTATAPSSSSLPTTTSTTAPTF---QPVFSSMGPPASVP 520

Query: 561 RPGVLQLNQTVGTNILPVNQPVRPGASQNTTF---LTSGSILRQLIPT---GKQVNGIPT 614
            P       T          P+  G +  T+    +TS S           G  +N + +
Sbjct: 521 LPAPFFKQTTTPATAPTTTAPLFTGLASATSAVAPITSASPSTDSASKPAFGFGINSVSS 580

Query: 615 YTLAPVSVTLPVPPGGLATVAPPQMPIQLLPSGAAAPMAGSMPGMPSPPVLVNAAQS--- 671
            +++  + T           AP        P+  +    G  P +P+   +   +QS   
Sbjct: 581 SSVSTTTSTATAASQPFLFGAPQASAASFTPAMGSIFQFGKPPALPTTTTVTTFSQSLPT 640

Query: 672 -VFVQASSSAAD 682
            V    SSSAAD
Sbjct: 641 AVPTATSSSAAD 652



 Score = 35.0 bits (79), Expect = 0.40
 Identities = 66/284 (23%), Positives = 93/284 (32%), Gaps = 42/284 (14%)

Query: 275 AAPANGSAPS---APAQPPCFHLALPQNSPSPAAGQPVTVAQGAPGSLTHSPPAAGQSHM 331
           +APA  S P+   +    P F++    ++ SP    P    Q A G+    PP A +  +
Sbjct: 663 SAPATSSQPTLTFSNTSTPTFNIPFGSSAKSPLPSYPGANPQPAFGAAEGQPPGAAKPAL 722

Query: 332 TLVSSPLPVGQNSLTLQP---PAPQPVFLSHGVPLHQSVNPPVLPLSQPVGPVNKSVG-- 386
           T          NS    P   P P P      VP H  V  P+ P     G  + + G  
Sbjct: 723 TPSFGSSFTFGNSAAPAPATAPTPAPASTIKIVPAH--VPTPIQPTFG--GATHSAFGLK 778

Query: 387 -------------------TSVLPINQTVRPGVLPLTQPVGPINRPVGPGVLPVSPSVTP 427
                              T+V         G    TQ     +     G    SP    
Sbjct: 779 ATASAFGAPASSQPAFGGSTAVFSFGAATSSGFGATTQTASSGSSSSVFGSTTPSPFTFG 838

Query: 428 GVLQAVSPGVLSVSRAVPSGVLPAGQMT-PAGQMTPAGVIPGQTATSGVLPTGQMVQSGV 486
           G       G   ++ A P      G  +  AGQ        G TATS    TG + Q+ +
Sbjct: 839 GSAAPAGSGSFGINVATPGSSATTGAFSFGAGQ-------SGSTATSTPF-TGGLGQNAL 890

Query: 487 LPVGQTAPSRVLPPGQTAPLRVISAGQVVPS-GLLSPNQTVSSS 529
              GQ+ P      G T   + +  G   P+ G  +P   V +S
Sbjct: 891 GTTGQSTPF-AFNVGSTTESKPVFGGTATPTFGQNTPAPGVGTS 933



 Score = 33.9 bits (76), Expect = 0.90
 Identities = 95/422 (22%), Positives = 137/422 (32%), Gaps = 62/422 (14%)

Query: 259 GLLKQTHIAPKPAAHLAA--PANGSAPSAPAQ-PPCFHLAL---PQNSPSPAAGQPVTVA 312
           GLL       KP   L    PA    P+   + PP         PQ + +P+     +  
Sbjct: 381 GLLPSPSFDSKPPTTLLGLIPAPSMVPATDTKAPPTLQAETATKPQATSAPSPAPKQSFL 440

Query: 313 QGAPGSLTHSPPAAGQSHMTLVSSPLPVGQNSLTLQPPAPQPVFLSHGVPLHQSVNPPVL 372
            G   +   SP A   S  + +  P+         + P P    ++   P   S+     
Sbjct: 441 FGTQNTSPSSPAAPAASSASPMFKPIFTAPPKSEKEGPTPPGPSVTATAPSSSSLPTTTS 500

Query: 373 PLSQPVGPVNKSVGTSV---LP---INQTVRPGVLPLTQPVGPINRPVGPGVLPVSP--S 424
             +    PV  S+G      LP     QT  P   P T    P+   +      V+P  S
Sbjct: 501 TTAPTFQPVFSSMGPPASVPLPAPFFKQTTTPATAPTT--TAPLFTGLASATSAVAPITS 558

Query: 425 VTPGVLQAVSP----GVLSVSRAVPSGVLPAGQMTPAGQMTPAGVIPGQTATSGVLPTGQ 480
            +P    A  P    G+ SVS +  S        T A Q    G  P  +A S     G 
Sbjct: 559 ASPSTDSASKPAFGFGINSVSSSSVS--TTTSTATAASQPFLFGA-PQASAASFTPAMGS 615

Query: 481 MVQSGVLPVGQTAPSRVLPPGQTAPLRVISAGQVVPSGLLSPNQTVSSSAVVPVNQGVNS 540
           + Q G             PP       V +  Q +P+ +  P  T SS+A      G  S
Sbjct: 616 IFQFG------------KPPALPTTTTVTTFSQSLPTAV--PTATSSSAADF---SGFGS 658

Query: 541 GVLQLSQPVVSGVLPVGQPVRPGVLQLNQTVGTNILPVNQ------PVRPGASQNTTFLT 594
             L  S P  S         +P +   N +  T  +P         P  PGA+    F  
Sbjct: 659 -TLATSAPATSS--------QPTLTFSNTSTPTFNIPFGSSAKSPLPSYPGANPQPAFGA 709

Query: 595 S-----GSILRQLIPTGKQVNGIPTYTLAPVSVTLPVP-PGGLATVAPPQMPIQLLPSGA 648
           +     G+    L P+          + AP   T P P P     + P  +P  + P+  
Sbjct: 710 AEGQPPGAAKPALTPSFGSSFTFGN-SAAPAPATAPTPAPASTIKIVPAHVPTPIQPTFG 768

Query: 649 AA 650
            A
Sbjct: 769 GA 770


>gi|4885407 hyperpolarization activated cyclic nucleotide-gated
            potassium channel 4 [Homo sapiens]
          Length = 1203

 Score = 55.5 bits (132), Expect = 3e-07
 Identities = 74/259 (28%), Positives = 99/259 (38%), Gaps = 48/259 (18%)

Query: 272  AHLAAPANGSA--PSAPAQPPCFHLALPQNSPSPAAGQPVTVAQGAPGSLTHSPPAAGQS 329
            A  +APA  S   PS+ + PP      P ++P+P+AG   T   G      H   A G S
Sbjct: 863  AGFSAPAGLSPLLPSSSSSPPPGACGSP-SAPTPSAGVAATTIAG----FGHFHKALGGS 917

Query: 330  HMTLVS---SPLPVGQNSLTLQPPAPQPVFLSHGVPLHQSVNPPVLPLSQPVGPVNKSVG 386
              +  S   +PL  G  S     P+P P     G+ L +   PP         P ++S  
Sbjct: 918  LSSSDSPLLTPLQPGARSPQAAQPSPAPPGARGGLGLPEHFLPPP--------PSSRSPS 969

Query: 387  TSVLPINQTVRPGVLPLTQPVGPINRPVGPGVLPVSPSVTPGVLQAVSPGVLSVSRAVPS 446
            +S   + Q   PG L L    GP++ P  P   P  PS+  G                  
Sbjct: 970  SSPGQLGQP--PGELSLGLATGPLSTPETPPRQPEPPSLVAG---------------ASG 1012

Query: 447  GVLPAGQMTPAGQMTPAGVIPGQTATSGVLPTGQMVQSGVL---PVGQTAPSRV------ 497
            G  P G  TP G ++P G  PG   T    P       G L   P     P +V      
Sbjct: 1013 GASPVG-FTPRGGLSPPGHSPGPPRTFPSAPPRASGSHGSLLLPPASSPPPPQVPQRRGT 1071

Query: 498  --LPPGQ-TAPLRVISAGQ 513
              L PG+ T  L++ISA Q
Sbjct: 1072 PPLTPGRLTQDLKLISASQ 1090



 Score = 34.3 bits (77), Expect = 0.69
 Identities = 79/336 (23%), Positives = 122/336 (36%), Gaps = 46/336 (13%)

Query: 358  SHGVPLHQSVNP---PVL--PLSQPVGPVNKSVGTSVLPINQTVRPGVLPLTQPVGPINR 412
            +H V    S  P   PV+  PL Q   P+  +  T+ + I  T  P +     P      
Sbjct: 756  AHRVQAAASATPTPTPVIWTPLIQ--APLQAAAATTSVAIALTHHPRL-----PAAIFRP 808

Query: 413  PVGPGVLPVSPSVTPGVLQAVSPGVLSVSRAVPSGVLPAGQMTPAGQMTPAGVIPGQTAT 472
            P G G+  +    TP  L+ +   + S   +      P+   TP+        + G +A 
Sbjct: 809  PPGSGLGNLGAGQTPRHLKRLQSLIPSALGSASPASSPSQVDTPSSSSFHIQQLAGFSAP 868

Query: 473  SGVLPTGQMVQSGVLPVGQTAPSRVLPPGQTAPLRVISAGQV--VPSGLLSPNQTVSSSA 530
            +G+ P      S   P    +PS   P    A   +   G       G LS +    S  
Sbjct: 869  AGLSPLLPSSSSSPPPGACGSPSAPTPSAGVAATTIAGFGHFHKALGGSLSSS---DSPL 925

Query: 531  VVPVNQGVNSGVLQLSQPVVSGVLPVGQPVRPGVLQLNQTVGTNILPVNQPVRPGASQNT 590
            + P+  G  S   Q +QP          P  PG        G   LP +    P +S++ 
Sbjct: 926  LTPLQPGARSP--QAAQP---------SPAPPGAR------GGLGLPEHFLPPPPSSRSP 968

Query: 591  TFLTSGSILRQLIPTGKQVNGIPTYTLAPVSV--TLPVPPGGLATVAPPQMPIQLLPSGA 648
            +  +S   L Q  P G+   G+ T  L+        P PP  +A  +    P+   P G 
Sbjct: 969  S--SSPGQLGQ--PPGELSLGLATGPLSTPETPPRQPEPPSLVAGASGGASPVGFTPRGG 1024

Query: 649  AAPMAGSMPGMP-----SPPVLVNAAQSVFVQASSS 679
             +P  G  PG P     +PP    +  S+ +  +SS
Sbjct: 1025 LSP-PGHSPGPPRTFPSAPPRASGSHGSLLLPPASS 1059


>gi|239752280 PREDICTED: similar to family with sequence similarity
           48, member B2 [Homo sapiens]
          Length = 779

 Score = 55.1 bits (131), Expect = 4e-07
 Identities = 84/320 (26%), Positives = 118/320 (36%), Gaps = 32/320 (10%)

Query: 286 PAQPPCFHLALPQNSPSPAAGQPVTVAQGAPGSLTHSPPAAGQSHMTLVSSPLPVGQNSL 345
           PA  P    A P  +P+PAA   +  A  A  +       A  SH    S PL       
Sbjct: 456 PAAAPAVAAAAPAPAPAPAAAPALAAAAVAAAA-----GGAAPSHSQKPSVPLIKASRR- 509

Query: 346 TLQPPAPQPV-FLSHGVPLHQSVNPPVLPLSQPVGPVNKS--VGTSVLPINQTVRPGVLP 402
             +P A +P  F+     +        L  +   GPV  +  +G S  P+         P
Sbjct: 510 --RPAAGRPTRFVKIAPAIQVRTGSTGLKATNVEGPVRGAQVLGCSFKPVQAPGSGAPAP 567

Query: 403 LTQPVGPINRPVGPGVLPVSPSVTPGVLQAVSPGVLSVSRAVPSGVLPAGQMTPAGQMTP 462
                  +    GP      P   PG +QA SP  L      P G+ P     P G    
Sbjct: 568 AGISGSGLQSSGGP-----LPDARPGAVQASSPAPLQFFLNTPEGLRPLTLQVPQGW--- 619

Query: 463 AGVIPGQTATSGVLPTGQMVQSGVLPVGQTAPSRVLPPGQTAPLRVISAGQVVPS-GLLS 521
             V+ G    S  L + Q +Q        TA     P  Q + L + + GQ  P+  LL+
Sbjct: 620 -AVLTGPQQQSHQLVSLQQLQQ------PTAAHPPQPGPQGSTLGLSTQGQAFPAQQLLN 672

Query: 522 PNQTVSSSAVVPVNQGVNSGVLQLSQPVVSGV-LP--VGQPVRPGVLQLNQTVGTNILPV 578
            N T + S + P  Q     +L  +Q    GV LP  +GQ  +P +L   Q     I   
Sbjct: 673 VNLTGAGSGLQPQPQAAVLSLLGSAQVPQQGVQLPFVLGQQPQPLLLLQPQPQPQQIQLQ 732

Query: 579 NQPVRPGASQNTTFLTSGSI 598
            QP+R    Q   FL +G++
Sbjct: 733 TQPLR--VLQQPVFLATGAV 750



 Score = 38.1 bits (87), Expect = 0.048
 Identities = 76/307 (24%), Positives = 111/307 (36%), Gaps = 39/307 (12%)

Query: 278 ANGSAPSAPAQP-PCFHLALPQNSPSPAAGQPVTVAQGAPGSLTHSPPAAGQSHMTLVSS 336
           A   +  +P QP P  H A  +      AG+ V+ AQ +  S    P     S     S 
Sbjct: 335 ARQKSQKSPWQPFPDDHSACLRPGSETDAGRAVSQAQESVQSKVKGPGKMSHSS----SG 390

Query: 337 PLPVGQNSLTLQPPAPQPVFLSHGVPLHQSVNPPVLPLSQ-PVGPVNKSVGTSVLPINQT 395
           P  V Q S    P  P PV++   V      +PP  P +Q P      S G S       
Sbjct: 391 PASVSQLSSWKTPEQPDPVWVQSSVSGKGEKHPP--PRTQLPSSSGKISSGNS------- 441

Query: 396 VRPGVLPLTQPVGPINRP---VGPGVLPVSPSVTPGVLQAVSPGVLSVSRAVPSGVLPAG 452
                 P  Q   P+ RP     P V   +P+  P    A +    +V+ A   G  P+ 
Sbjct: 442 -----FPPQQAGSPLKRPFPAAAPAVAAAAPAPAPAPAAAPALAAAAVA-AAAGGAAPSH 495

Query: 453 QMTP------AGQMTPAGVIPG---QTATSGVLPTGQMVQSGVLPVGQTAPSRVLPPGQT 503
              P      A +  PA   P    + A +  + TG          G    ++VL     
Sbjct: 496 SQKPSVPLIKASRRRPAAGRPTRFVKIAPAIQVRTGSTGLKATNVEGPVRGAQVL-GCSF 554

Query: 504 APLRVISAGQVVPSGLLSPNQTVSSSAVVPVNQGVNSGVLQLSQPV-VSGVLPVGQPVRP 562
            P++   +G   P+G +S +   SS   +P       G +Q S P  +   L   + +RP
Sbjct: 555 KPVQAPGSGAPAPAG-ISGSGLQSSGGPLP---DARPGAVQASSPAPLQFFLNTPEGLRP 610

Query: 563 GVLQLNQ 569
             LQ+ Q
Sbjct: 611 LTLQVPQ 617


>gi|19924097 synapsin I isoform Ib [Homo sapiens]
          Length = 669

 Score = 55.1 bits (131), Expect = 4e-07
 Identities = 78/275 (28%), Positives = 102/275 (37%), Gaps = 39/275 (14%)

Query: 240 HRDLENKL--RSVISEHIKRTGLLKQTHIAPKPAAHLAAPANGSAP------SAPAQPPC 291
           H+D + +L    V+++  +     +Q   +P   +H   P+ G+ P        PA PP 
Sbjct: 398 HQDEDKQLIVELVVNKMAQALPRQRQRDASPGRGSHGQTPSPGALPLGRQTSQQPAGPPA 457

Query: 292 FHLALPQNSPSPAAGQPVTVAQGAPGSLTHSPPAAGQSHMT----LVSSPLPVGQNSLTL 347
                PQ  P P  G P    QG P  L   PP  GQ H++       SPLP    S T 
Sbjct: 458 QQRPPPQGGP-PQPG-PGPQRQGPP--LQQRPPPQGQQHLSGLGPPAGSPLPQRLPSPTS 513

Query: 348 QPPAP---------------QPVFLSHGVPLHQSVNPPVLPLSQ-PVGPVNKSVGTSVLP 391
            P  P               +PV    G P   +  PP  P  Q   GP   +  TSV  
Sbjct: 514 APQQPASQAAPPTQGQGRQSRPVAGGPGAP--PAARPPASPSPQRQAGPPQATRQTSVSG 571

Query: 392 INQTVRPGVLP-LTQPVGPINRPVGPGVLPVSPSVTPGVLQAVSPGVLSVSRAVPSGVLP 450
                  G  P   Q  GP  +P GP   P   +   G +    P      R  PSG  P
Sbjct: 572 PAPPKASGAPPGGQQRQGPPQKPPGPAG-PTRQASQAGPVPRTGPPTTQQPR--PSGPGP 628

Query: 451 AGQMTPAGQMTPA-GVIPGQTATSGVLPTGQMVQS 484
           AG+  P     P+  V P  TA +G  P  Q+  S
Sbjct: 629 AGRPKPQLAQKPSQDVPPPATAAAGGPPHPQLKAS 663



 Score = 37.7 bits (86), Expect = 0.062
 Identities = 68/272 (25%), Positives = 80/272 (29%), Gaps = 56/272 (20%)

Query: 394 QTVRPGVLPL-----TQPVGPINRPVGPGVLPVSPSVTPGVLQAVSPGVLSVSRAVPSGV 448
           QT  PG LPL      QP GP  +   P   P      PG      PG       +    
Sbjct: 435 QTPSPGALPLGRQTSQQPAGPPAQQRPP---PQGGPPQPG------PGPQRQGPPLQQRP 485

Query: 449 LPAGQMTPAGQMTPAGV-----------IPGQTATSGVLPT-GQMVQSGVLPVGQTAPSR 496
            P GQ   +G   PAG             P Q A+    PT GQ  QS  +  G  AP  
Sbjct: 486 PPQGQQHLSGLGPPAGSPLPQRLPSPTSAPQQPASQAAPPTQGQGRQSRPVAGGPGAPPA 545

Query: 497 VLPPGQTAPLRVISAGQVVPSGLLSPNQTVSSSAVVPVNQGVNSGVLQLSQPVVSGVLPV 556
             PP   +P R     Q          QT  S    P   G   G  Q   P      P 
Sbjct: 546 ARPPASPSPQRQAGPPQAT-------RQTSVSGPAPPKASGAPPGGQQRQGPPQKPPGPA 598

Query: 557 GQPVRPGVLQLNQTVGTNILPVNQPVRPGASQNTTFLTSGSILRQLIPTGKQVNGIPTYT 616
           G                       P R  +       T     +Q  P+G    G P   
Sbjct: 599 G-----------------------PTRQASQAGPVPRTGPPTTQQPRPSGPGPAGRPKPQ 635

Query: 617 LAPVSVTLPVPPGGLATVAPPQMPIQLLPSGA 648
           LA        PP   A   PP   ++  P+ A
Sbjct: 636 LAQKPSQDVPPPATAAAGGPPHPQLKASPAQA 667


>gi|7662236 TSC22 domain family, member 2 [Homo sapiens]
          Length = 780

 Score = 55.1 bits (131), Expect = 4e-07
 Identities = 108/420 (25%), Positives = 142/420 (33%), Gaps = 82/420 (19%)

Query: 277 PANGSAPSAPAQPPCFHLALPQNSPSPAAGQPVTVAQGA------PGSLT---------- 320
           P+   +   PAQP  F +  PQ  P P  G    VAQ +      PG+ T          
Sbjct: 254 PSEKMSQPTPAQPQSFSVGQPQPPPPPVGG---AVAQSSAPLPPFPGAATGPQPMMAAAQ 310

Query: 321 -HSPPAAGQSHMTLVSSPLPVGQNSLTLQPPAPQPVFLSHGVPLHQSVNPPVLPLSQ-PV 378
              P  AG    TL  + + + Q +++L PP P P     G P  Q       P  Q P 
Sbjct: 311 PSQPQGAGPGGQTLPPTNVTLAQPAMSL-PPQPGPAV---GAPAAQQPQQFAYPQPQIPP 366

Query: 379 G---PVNKSVGTSVLPINQT-VRPGVLPLTQPVGPINRPVGPGVLPVSPSVTPGVLQAVS 434
           G   PV  S  +  L  +   ++P         G    P     LPV        + A  
Sbjct: 367 GHLLPVQPSGQSEYLQQHVAGLQPPSPAQPSSTGAAASPATAATLPVGTGQNASSVGAQL 426

Query: 435 PGVL---SVSRAVPSGVLPAGQMTPAGQMTPAGVIPGQTATSGVLPTGQMVQSGVLPVGQ 491
            G     S + A  +G    GQ+ P     P GV P           G +VQ  + P G 
Sbjct: 427 MGASSQPSEAMAPRTGPAQGGQVAPC---QPTGVPPA--------TVGGVVQPCLGPAGA 475

Query: 492 TAPSRVLPP--GQTAPLRVISAGQVVPSGLLSPNQTVSSSAVVPVNQGVNSGVLQLSQPV 549
             P  V PP  G + PL  +  G                 AVVP    V + V   S P 
Sbjct: 476 GQPQSVPPPQMGGSGPLSAVPGG---------------PHAVVPGVPNVPAAVPAPSVPS 520

Query: 550 VSGVLPVGQPVRPGVLQLNQTVGTN---------ILPVNQPVRPGASQNTTFLTSGSILR 600
           VS    V  P  P  L  +Q + ++         I  V  P+ PG     T L    + +
Sbjct: 521 VS-TTSVTMPNVPAPLAQSQQLSSHTPVSRSSSIIQHVGLPLAPGTHSAPTSLPQSDLSQ 579

Query: 601 QLIPTGKQVNGIPTYTLAPVSVTLPVPPGGL-----ATVAPP-----QMPIQLLPSGAAA 650
               T   V  +        S  LP PP  L       V PP       P+QL P  + A
Sbjct: 580 FQTQTQPLVGQVD--DTRRKSEPLPQPPLSLIAENKPVVKPPVADSLANPLQLTPMNSLA 637



 Score = 30.8 bits (68), Expect = 7.6
 Identities = 49/200 (24%), Positives = 67/200 (33%), Gaps = 35/200 (17%)

Query: 263 QTHIAPKPAAHLAAPANGSAPSAPAQPPCFHLALPQNSPSPAAGQPVTVAQGAPGSLTHS 322
           Q H+A       A P++  A ++PA      +   QN+ S  A      +Q +      +
Sbjct: 382 QQHVAGLQPPSPAQPSSTGAAASPATAATLPVGTGQNASSVGAQLMGASSQPSEAMAPRT 441

Query: 323 PPAAGQSHMTLVSSPLPVGQNSLTLQPPAPQPVFLSHGVPLHQSVNPPVLPLSQPVGPVN 382
            PA G      V+   P G    T+     QP     G    QSV PP +  S P+  V 
Sbjct: 442 GPAQGGQ----VAPCQPTGVPPATV-GGVVQPCLGPAGAGQPQSVPPPQMGGSGPLSAV- 495

Query: 383 KSVGTSVLPINQTVRPGVLPLTQPVGPINRPVGPGVLPVSPSVTPGVLQAVSPGVLSVSR 442
                                  P GP    V PGV    P+V   V     P V + S 
Sbjct: 496 -----------------------PGGP--HAVVPGV----PNVPAAVPAPSVPSVSTTSV 526

Query: 443 AVPSGVLPAGQMTPAGQMTP 462
            +P+   P  Q       TP
Sbjct: 527 TMPNVPAPLAQSQQLSSHTP 546


>gi|210032463 family with sequence similarity 48, member B2 [Homo
           sapiens]
          Length = 817

 Score = 55.1 bits (131), Expect = 4e-07
 Identities = 84/320 (26%), Positives = 118/320 (36%), Gaps = 32/320 (10%)

Query: 286 PAQPPCFHLALPQNSPSPAAGQPVTVAQGAPGSLTHSPPAAGQSHMTLVSSPLPVGQNSL 345
           PA  P    A P  +P+PAA   +  A  A  +       A  SH    S PL       
Sbjct: 494 PAAAPAVAAAAPAPAPAPAAAPALAAAAVAAAA-----GGAAPSHSQKPSVPLIKASRR- 547

Query: 346 TLQPPAPQPV-FLSHGVPLHQSVNPPVLPLSQPVGPVNKS--VGTSVLPINQTVRPGVLP 402
             +P A +P  F+     +        L  +   GPV  +  +G S  P+         P
Sbjct: 548 --RPAAGRPTRFVKIAPAIQVRTGSTGLKATNVEGPVRGAQVLGCSFKPVQAPGSGAPAP 605

Query: 403 LTQPVGPINRPVGPGVLPVSPSVTPGVLQAVSPGVLSVSRAVPSGVLPAGQMTPAGQMTP 462
                  +    GP      P   PG +QA SP  L      P G+ P     P G    
Sbjct: 606 AGISGSGLQSSGGP-----LPDARPGAVQASSPAPLQFFLNTPEGLRPLTLQVPQGW--- 657

Query: 463 AGVIPGQTATSGVLPTGQMVQSGVLPVGQTAPSRVLPPGQTAPLRVISAGQVVPS-GLLS 521
             V+ G    S  L + Q +Q        TA     P  Q + L + + GQ  P+  LL+
Sbjct: 658 -AVLTGPQQQSHQLVSLQQLQQ------PTAAHPPQPGPQGSTLGLSTQGQAFPAQQLLN 710

Query: 522 PNQTVSSSAVVPVNQGVNSGVLQLSQPVVSGV-LP--VGQPVRPGVLQLNQTVGTNILPV 578
            N T + S + P  Q     +L  +Q    GV LP  +GQ  +P +L   Q     I   
Sbjct: 711 VNLTGAGSGLQPQPQAAVLSLLGSAQVPQQGVQLPFVLGQQPQPLLLLQPQPQPQQIQLQ 770

Query: 579 NQPVRPGASQNTTFLTSGSI 598
            QP+R    Q   FL +G++
Sbjct: 771 TQPLR--VLQQPVFLATGAV 788



 Score = 38.1 bits (87), Expect = 0.048
 Identities = 76/307 (24%), Positives = 111/307 (36%), Gaps = 39/307 (12%)

Query: 278 ANGSAPSAPAQP-PCFHLALPQNSPSPAAGQPVTVAQGAPGSLTHSPPAAGQSHMTLVSS 336
           A   +  +P QP P  H A  +      AG+ V+ AQ +  S    P     S     S 
Sbjct: 373 ARQKSQKSPWQPFPDDHSACLRPGSETDAGRAVSQAQESVQSKVKGPGKMSHSS----SG 428

Query: 337 PLPVGQNSLTLQPPAPQPVFLSHGVPLHQSVNPPVLPLSQ-PVGPVNKSVGTSVLPINQT 395
           P  V Q S    P  P PV++   V      +PP  P +Q P      S G S       
Sbjct: 429 PASVSQLSSWKTPEQPDPVWVQSSVSGKGEKHPP--PRTQLPSSSGKISSGNS------- 479

Query: 396 VRPGVLPLTQPVGPINRP---VGPGVLPVSPSVTPGVLQAVSPGVLSVSRAVPSGVLPAG 452
                 P  Q   P+ RP     P V   +P+  P    A +    +V+ A   G  P+ 
Sbjct: 480 -----FPPQQAGSPLKRPFPAAAPAVAAAAPAPAPAPAAAPALAAAAVA-AAAGGAAPSH 533

Query: 453 QMTP------AGQMTPAGVIPG---QTATSGVLPTGQMVQSGVLPVGQTAPSRVLPPGQT 503
              P      A +  PA   P    + A +  + TG          G    ++VL     
Sbjct: 534 SQKPSVPLIKASRRRPAAGRPTRFVKIAPAIQVRTGSTGLKATNVEGPVRGAQVL-GCSF 592

Query: 504 APLRVISAGQVVPSGLLSPNQTVSSSAVVPVNQGVNSGVLQLSQPV-VSGVLPVGQPVRP 562
            P++   +G   P+G +S +   SS   +P       G +Q S P  +   L   + +RP
Sbjct: 593 KPVQAPGSGAPAPAG-ISGSGLQSSGGPLP---DARPGAVQASSPAPLQFFLNTPEGLRP 648

Query: 563 GVLQLNQ 569
             LQ+ Q
Sbjct: 649 LTLQVPQ 655


>gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo
           sapiens]
          Length = 855

 Score = 54.3 bits (129), Expect = 6e-07
 Identities = 74/278 (26%), Positives = 100/278 (35%), Gaps = 33/278 (11%)

Query: 275 AAPANGSAPSAPAQPPCFHLALPQNSPSPAAGQP----VTVAQGAPGSLTHSPPAAGQSH 330
           AAPA G   S+P   P    AL   +P      P    +T     P  L    P+A  S 
Sbjct: 292 AAPALGPLSSSPLATPSPSAALQSQAPPTLPATPHSSSLTCQLATPLPLAPPSPSAPPSL 351

Query: 331 MTLVSSPL-PVGQNSLTLQPPAPQPVFLSHGVPLHQSV-NPPVLPLSQPVGPVNKSVGTS 388
            TL S P  P  Q + +L  P  Q          H  + +PP+ PL+ P  P       +
Sbjct: 352 QTLPSPPATPPSQATTSLGSPTLQAT--------HSFLPSPPLSPLATP--PPQAPPALA 401

Query: 389 VLPINQTVRPGVLPLTQPVGPINRPV--GPGVL-------PVSPSVTPGVLQAVSPGVLS 439
           + P+     P   P + P+ P+  P    P  L       P SP  +P V    SP    
Sbjct: 402 LPPLQAPPSP---PASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSP---P 455

Query: 440 VSRAVPSGVLPAGQMTPAGQMTPAGVIPGQTATSGVLPTGQMVQSGVLPVGQTAPSRVLP 499
            S  V     P  Q  P+    P  V P   A+  + P+         P+         P
Sbjct: 456 ASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKP 515

Query: 500 PGQTAPLRVISAGQVVPSGLLS-PNQT-VSSSAVVPVN 535
           P Q  P       Q +PS   S P Q   S SA +P++
Sbjct: 516 PPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMS 553



 Score = 52.8 bits (125), Expect = 2e-06
 Identities = 104/422 (24%), Positives = 141/422 (33%), Gaps = 71/422 (16%)

Query: 267 APKPAAHLAAPANGSAPSAPAQPPCFHLALPQNSPSPAAGQPVTVAQGAPGSLTHSPPAA 326
           APK +A  A     ++   P  P     +      S AAG  V + + AP +    P   
Sbjct: 150 APKRSALSAGARRDTSGPTPGTP-----SPAMARRSRAAGTEVGLPRPAPSARPRPPTEG 204

Query: 327 GQSHMTLVSSPLPVGQNSLTLQPPAPQPVFLSHGV---PLHQSVNPPVLPLSQPVGPVNK 383
            +  ++  S      ++S T   PA +    + G    P  +S++    PLS P      
Sbjct: 205 PRKSVSSAS------EHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPS 258

Query: 384 SVGTSVLPIN--QTVRPGVLPLTQP-VGPINRPVGPGVLPVS--PSVTPG---VLQAVSP 435
           + GT   P +  Q    G+  L  P V P  +   P + P+S  P  TP     LQ+ +P
Sbjct: 259 ARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAALQSQAP 318

Query: 436 GVLSVSR---------AVPSGVLPAGQMTPAGQMT---PAGVIPGQTATSGVLPTGQMVQ 483
             L  +          A P  + P     P    T   P    P Q  TS   PT Q   
Sbjct: 319 PTLPATPHSSSLTCQLATPLPLAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATH 378

Query: 484 SGVLPVGQTAPSRVLPPGQTAPLRVISAGQVVPSGLLSPNQTVSSSAVVPVNQGVNSGVL 543
           S  LP    +P    PP Q  P   +   Q  PS   SP     S    P  Q  N+  +
Sbjct: 379 S-FLPSPPLSPLAT-PPPQAPPALALPPLQAPPSPPASPPL---SPLATPSPQAPNALAV 433

Query: 544 QLSQPVVSGVLPVGQPVRPGVLQLNQTVGTNILPVNQPVRPGASQNTTFLTSGSILRQLI 603
            L Q       P   P  P              PV  P  P AS   +            
Sbjct: 434 HLLQA------PFSPPPSP--------------PVQAPFSPPASPPVS------------ 461

Query: 604 PTGKQVNGIPTYTLAPVSVTLPVPPGGLATVAPPQMPIQLLPSGAAAPMAGSMPGMPSPP 663
           P+    +  P    AP     P PP           P Q  P  AA P+  + P   +PP
Sbjct: 462 PSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPP 521

Query: 664 VL 665
            L
Sbjct: 522 AL 523



 Score = 48.9 bits (115), Expect = 3e-05
 Identities = 91/379 (24%), Positives = 132/379 (34%), Gaps = 54/379 (14%)

Query: 304 AAGQPVTVAQGAPGSLTHSPPAAGQSHMTLVSSPLPVGQNSLTLQPPAPQPVFLSHGVPL 363
           +AG     +   PG  T SP  A +S        LP    S   +PP   P         
Sbjct: 157 SAGARRDTSGPTPG--TPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASE 214

Query: 364 HQSVNPPVLPLSQPVG------PVNKSVGTSVLPINQTVRPGVLPLTQPVGPINRPVGPG 417
           H +  P      +P        P ++S+ +S  P++   R G      P  P +      
Sbjct: 215 HSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAH------ 268

Query: 418 VLPVSPSVTPGVLQAVSPGVLSVSRAVPSGVLPAGQMTPAGQMTPAGVIPGQTATSGVLP 477
             P  P   P  LQA+ P  ++  R   +  L     +P    +P+  +  Q   +  LP
Sbjct: 269 --PSQPK--PKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAALQSQAPPT--LP 322

Query: 478 TGQMVQSGVLPVGQTAPSRVLPPGQTAPLRVISAGQVVPSGLLSPNQTVSSSAVVPVNQG 537
                 S  L      P  + PP  +AP  +    Q +PS   +P    ++S   P  Q 
Sbjct: 323 ATP--HSSSLTCQLATPLPLAPPSPSAPPSL----QTLPSPPATPPSQATTSLGSPTLQA 376

Query: 538 VNSGVLQLSQPVVSGVLPVGQPVRPGVLQLNQTVGTNILPVNQPVRPGASQNTTFLTSGS 597
            +S    L  P +S  L    P  P  L L         P+  P  P AS   + L +  
Sbjct: 377 THSF---LPSPPLSP-LATPPPQAPPALALP--------PLQAPPSPPASPPLSPLAT-- 422

Query: 598 ILRQLIPTGKQVNGIPTYTL-APVS------VTLPVPPGGLATVAPPQMPIQLLPSGAAA 650
                 P+ +  N +  + L AP S      V  P  P     V+P   P    P   AA
Sbjct: 423 ------PSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAA 476

Query: 651 PMAGSMPGMP-SPPVLVNA 668
           P     P  P SPP+  +A
Sbjct: 477 PPLQVPPSPPASPPMSPSA 495



 Score = 47.4 bits (111), Expect = 8e-05
 Identities = 64/235 (27%), Positives = 88/235 (37%), Gaps = 17/235 (7%)

Query: 268 PKPAAHLAAPANGSAPSAPAQPPCFHLALPQNSPSPAAGQPVTV-AQGAPGSLTHSPPAA 326
           P+    LA P   + PS PA PP   LA    +PSP A   + V    AP S   SPP  
Sbjct: 394 PQAPPALALPPLQAPPSPPASPPLSPLA----TPSPQAPNALAVHLLQAPFSPPPSPPV- 448

Query: 327 GQSHMTLVSSPLPVGQNSLTLQPPAPQPVFLSHGVPLHQSVNPPVLPLSQP--VGPVNKS 384
            Q+  +  +SP PV   S +  PP+  P  L+   PL    +PP  P   P    P    
Sbjct: 449 -QAPFSPPASP-PV---SPSATPPSQAPPSLA-APPLQVPPSPPASPPMSPSATPPPQAP 502

Query: 385 VGTSVLPINQTVRPGVLPLTQPVGPINR-PVGPGVLPVSPSVTPGVLQAVSPGVLSVSRA 443
              +  P+     P   P      P+   P  P   P     +P     +SP      +A
Sbjct: 503 PPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQA 562

Query: 444 VPSGVLPAGQMTPAGQMTPAGVIPGQTATSG--VLPTGQMVQSGVLPVGQTAPSR 496
            P    P  Q+ P+   +P    P +  T G     +G  +   + P     PSR
Sbjct: 563 PPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSR 617



 Score = 43.5 bits (101), Expect = 0.001
 Identities = 55/203 (27%), Positives = 76/203 (37%), Gaps = 15/203 (7%)

Query: 261 LKQTHIAPKPAAHLAAPANGSAPSAPAQPPCFHLALPQNSPSPA-AGQPVTVAQGAPGSL 319
           L Q   +P P+  + AP      S PA PP    A P +   P+ A  P+ V    P S 
Sbjct: 435 LLQAPFSPPPSPPVQAPF-----SPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASP 489

Query: 320 THSPPAAGQSHMTLVSSPLPVGQNSLTLQPPAPQPVFLSHGVPLHQSVNPPV-LPLSQPV 378
             SP A          +P P+    L L  P PQ        PL    +PP   P   P 
Sbjct: 490 PMSPSATPPP-----QAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPF 544

Query: 379 GPVNKSVGTSVLPINQTVRPGVLPLTQPVGPINRPVGPGVLPVSPSVTPGVLQAVSPGVL 438
            P + S+  S L       P VL       P + P  P +       TPG   +VS   L
Sbjct: 545 SP-SASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRL 603

Query: 439 SVSRAVPSGVLPAGQMTPAGQMT 461
           ++  A+  G  P    +P+  ++
Sbjct: 604 TL--ALAPGPPPPPSRSPSSTLS 624



 Score = 40.8 bits (94), Expect = 0.007
 Identities = 49/195 (25%), Positives = 70/195 (35%), Gaps = 30/195 (15%)

Query: 274 LAAPANGSAPSAPAQPPCFHLALPQ-NSPSPAAGQPVTVAQGAPGSLTHSPPAAGQSHMT 332
           LAAP     PS PA PP    A P   +P P A  P+ +A+  P     +PPA     + 
Sbjct: 474 LAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPP----QAPPALATPPLQ 529

Query: 333 LVSSPLPVGQNSLTLQPPAPQPVFLSHGVPLHQSVNPPVLPLSQPVGPVNKSVGTSVLPI 392
            + SP                P       P   S + P+ PL+ P       +   +L +
Sbjct: 530 ALPSP----------------PASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQV 573

Query: 393 NQTVRPGVLPLTQPVGPINRPVGPGVLPVSPSVTPGVLQAVSPGVLSVSRAVPSGVLPAG 452
                P   P +  +    RP  PG  P +    P +  A++PG        PS  L   
Sbjct: 574 -----PPSPPASPTLQAPRRPPTPG--PDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGP 626

Query: 453 QMTPAGQMTPAGVIP 467
            +  AG  + A   P
Sbjct: 627 DL--AGHSSSATSTP 639



 Score = 34.7 bits (78), Expect = 0.53
 Identities = 82/355 (23%), Positives = 117/355 (32%), Gaps = 66/355 (18%)

Query: 349 PPAPQPVFLSHGVPLHQSVNPPVLPLSQPVGPVNKSVGTSVLPINQTVRPGVLPLTQPVG 408
           P A  P  L+   P      PPV P +  V     +VG               PL +  G
Sbjct: 17  PAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRK-------------PLAERAG 63

Query: 409 PINRPVGPGVLPVSPSVTPGVLQAVSPGVLSVSRAVPSGVLPAGQMTPAGQMTPAGVIPG 468
            I    G   +P S         A +      SR   SG    G+  P  + T  G +  
Sbjct: 64  GI----GGATIPESAPRAGPTRSAGTSSRNPASRPPASG---RGERAPPAKNTSPGPVSS 116

Query: 469 QTATSGVLPTGQMVQSGV---------------------LPVGQTAPSRVLPPGQTAPL- 506
               SG    G + Q G+                     L  G    +    PG  +P  
Sbjct: 117 PGRASGTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAM 176

Query: 507 --RVISAGQVVPSGLLSPNQTVSSSAVVPVNQGVNSGVLQLSQPVVSGVLPVGQ--PVRP 562
             R  +AG  V  GL  P     S+   P  +G    V   S+   +   P  +  P   
Sbjct: 177 ARRSRAAGTEV--GLPRP---APSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAG 231

Query: 563 GVLQ--LNQTVGTNILPVNQPVRPGASQNTTFLTSGSILRQLIPTGKQVNGIPTYT---- 616
           G LQ   ++++ ++  P++ P R G S   T   + +   Q  P G Q    P  T    
Sbjct: 232 GGLQRPASRSLSSSATPLSSPARSGPSARGT-PRAPAHPSQPKPKGLQALRPPQVTPPRK 290

Query: 617 -----LAPVS---VTLPVPPGGLATVAPPQMPIQLLPSGAAAPMAGSMPGMPSPP 663
                L P+S   +  P P   L + APP +P     S     +A  +P  P  P
Sbjct: 291 DAAPALGPLSSSPLATPSPSAALQSQAPPTLPATPHSSSLTCQLATPLPLAPPSP 345


>gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo
           sapiens]
          Length = 816

 Score = 54.3 bits (129), Expect = 6e-07
 Identities = 97/377 (25%), Positives = 121/377 (32%), Gaps = 55/377 (14%)

Query: 304 AAGQPVTVAQGAPGSLTHSPPAAGQSHMTLVSSPLPVGQNSLTLQPPAPQPVFLSHGVPL 363
           +AG     +   PG  T SP  A +S        LP    S   +PP   P         
Sbjct: 148 SAGARRDTSGPTPG--TPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASE 205

Query: 364 HQSVNPPVLPLSQPVG------PVNKSVGTSVLPINQTVRPGVLPLTQPVGPIN----RP 413
           H +  P      +P        P ++S+ +S  P++   R G      P  P +    +P
Sbjct: 206 HSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKP 265

Query: 414 VGPGVLPVSPSVTPGVLQAVSP-GVLSVSR-AVPSGVLPAGQMTPAGQMT---PAGVIPG 468
            G   L   P VTP    A    G LS S  A PS   P     P    T   P    P 
Sbjct: 266 KGLQALR-PPQVTPPRKDAAPALGPLSSSPLATPSPSAPPSPSAPPSLQTLPSPPATPPS 324

Query: 469 QTATSGVLPTGQMVQSGVLPVGQTAPSRVLPPGQTAPLRVISAGQVVPSGLLSPNQTVSS 528
           Q  TS   PT Q   S  LP    +P    PP Q  P   +   Q  PS   SP     S
Sbjct: 325 QATTSLGSPTLQATHS-FLPSPPLSPLAT-PPPQAPPALALPPLQAPPSPPASPPL---S 379

Query: 529 SAVVPVNQGVNSGVLQLSQPVVSGVLPVGQPVRPGVLQLNQTVGTNILPVNQPVRPGASQ 588
               P  Q  N+  + L Q       P   P  P              PV  P  P AS 
Sbjct: 380 PLATPSPQAPNALAVHLLQA------PFSPPPSP--------------PVQAPFSPPASP 419

Query: 589 NTTFLTSGSILRQLIPTGKQVNGIPTYTLAPVSVTLPVPPGGLATVAPPQMPIQLLPSGA 648
             +            P+    +  P    AP     P PP           P Q  P  A
Sbjct: 420 PVS------------PSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLA 467

Query: 649 AAPMAGSMPGMPSPPVL 665
           A P+  + P   +PP L
Sbjct: 468 APPLQLAKPPPQAPPAL 484



 Score = 47.4 bits (111), Expect = 8e-05
 Identities = 68/257 (26%), Positives = 85/257 (33%), Gaps = 56/257 (21%)

Query: 271 AAHLAAPANGSAPSA---PAQPPCFHLALPQNSPSPAAGQPVTVAQGAPGSLTHSPPAAG 327
           A H   P+   +P A   P  PP   L   Q  PSP A  P++         T SP A  
Sbjct: 337 ATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPL------ATPSPQAPN 390

Query: 328 QSHMTLVSSPLPVGQNSLTLQPPAPQPVFLSHGVPLHQSVNPPVLPLSQPVGPVNKSVGT 387
              + L+ +P           PP   PV      P     +PPV P + P          
Sbjct: 391 ALAVHLLQAP---------FSPPPSPPV----QAPFSPPASPPVSPSATP---------P 428

Query: 388 SVLPINQTVRPGVLPLTQPVGPINRPVGPGVLPVSPSVTPGVLQAVSPGVLSVSRAVPSG 447
           S  P +    P  +P + P  P          P+SPS TP            +  A P  
Sbjct: 429 SQAPPSLAAPPLQVPPSPPASP----------PMSPSATPPPQAPPPLAAPPLQLAKPPP 478

Query: 448 VLPAGQMTPAGQM--TPAGVIPGQTATSGVLPTGQMVQSGVLPVGQTAPSRVLPPGQTAP 505
             P    TP  Q   +P    PGQ   S          S  LP+   A     PP Q  P
Sbjct: 479 QAPPALATPPLQALPSPPASFPGQAPFS---------PSASLPMSPLA----TPPPQAPP 525

Query: 506 LRVISAGQVVPSGLLSP 522
           +      QV PS   SP
Sbjct: 526 VLAAPLLQVPPSPPASP 542



 Score = 47.4 bits (111), Expect = 8e-05
 Identities = 64/235 (27%), Positives = 88/235 (37%), Gaps = 17/235 (7%)

Query: 268 PKPAAHLAAPANGSAPSAPAQPPCFHLALPQNSPSPAAGQPVTV-AQGAPGSLTHSPPAA 326
           P+    LA P   + PS PA PP   LA    +PSP A   + V    AP S   SPP  
Sbjct: 355 PQAPPALALPPLQAPPSPPASPPLSPLA----TPSPQAPNALAVHLLQAPFSPPPSPPV- 409

Query: 327 GQSHMTLVSSPLPVGQNSLTLQPPAPQPVFLSHGVPLHQSVNPPVLPLSQP--VGPVNKS 384
            Q+  +  +SP PV   S +  PP+  P  L+   PL    +PP  P   P    P    
Sbjct: 410 -QAPFSPPASP-PV---SPSATPPSQAPPSLA-APPLQVPPSPPASPPMSPSATPPPQAP 463

Query: 385 VGTSVLPINQTVRPGVLPLTQPVGPINR-PVGPGVLPVSPSVTPGVLQAVSPGVLSVSRA 443
              +  P+     P   P      P+   P  P   P     +P     +SP      +A
Sbjct: 464 PPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQA 523

Query: 444 VPSGVLPAGQMTPAGQMTPAGVIPGQTATSG--VLPTGQMVQSGVLPVGQTAPSR 496
            P    P  Q+ P+   +P    P +  T G     +G  +   + P     PSR
Sbjct: 524 PPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSR 578



 Score = 43.5 bits (101), Expect = 0.001
 Identities = 55/203 (27%), Positives = 76/203 (37%), Gaps = 15/203 (7%)

Query: 261 LKQTHIAPKPAAHLAAPANGSAPSAPAQPPCFHLALPQNSPSPA-AGQPVTVAQGAPGSL 319
           L Q   +P P+  + AP      S PA PP    A P +   P+ A  P+ V    P S 
Sbjct: 396 LLQAPFSPPPSPPVQAPF-----SPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASP 450

Query: 320 THSPPAAGQSHMTLVSSPLPVGQNSLTLQPPAPQPVFLSHGVPLHQSVNPPV-LPLSQPV 378
             SP A          +P P+    L L  P PQ        PL    +PP   P   P 
Sbjct: 451 PMSPSATPPP-----QAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPF 505

Query: 379 GPVNKSVGTSVLPINQTVRPGVLPLTQPVGPINRPVGPGVLPVSPSVTPGVLQAVSPGVL 438
            P + S+  S L       P VL       P + P  P +       TPG   +VS   L
Sbjct: 506 SP-SASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRL 564

Query: 439 SVSRAVPSGVLPAGQMTPAGQMT 461
           ++  A+  G  P    +P+  ++
Sbjct: 565 TL--ALAPGPPPPPSRSPSSTLS 585



 Score = 42.0 bits (97), Expect = 0.003
 Identities = 109/443 (24%), Positives = 156/443 (35%), Gaps = 79/443 (17%)

Query: 266 IAPKPAAHLAAPANGSA--PSAPAQPPCFHLALPQNSPSPAAGQPVTVAQGAPGSLTHSP 323
           +  KP A  A    G+    SAP   P       + S  PA+G+     + AP +   SP
Sbjct: 53  VGRKPLAERAGGIGGATIPESAPRAGPT------RTSRPPASGR----GERAPPAKNTSP 102

Query: 324 -PAAGQSHMTLVSSPLPVGQNSLTLQPP----------APQPVFLSHGVPLHQSVNPPVL 372
            P +     +  + P P+GQ  L +             AP+   LS G     S   P  
Sbjct: 103 GPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGT 162

Query: 373 PLSQPVGPVNKSVGTSV-LPINQTVRPGVLPLTQPVGPINRPVGPGVLPVSPSVTPGVLQ 431
           P S  +   +++ GT V LP      P   P     GP  + V       +   +P   +
Sbjct: 163 P-SPAMARRSRAAGTEVGLP---RPAPSARPRPPTEGP-RKSVSSASEHSTTEPSPAARR 217

Query: 432 AVSPG---VLSVSRAVPSGVLPAGQMT---PAGQMTP-AGVIPGQTATSG--------VL 476
             S G       SR++ S   P        P+ + TP A   P Q    G        V 
Sbjct: 218 RPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVT 277

Query: 477 PTGQMVQSGVLPVGQT---APSRVLPPGQTAPLRVISAGQVVPSGLLSPNQTVSSSAVVP 533
           P  +     + P+  +    PS   PP  +AP  +    Q +PS   +P    ++S   P
Sbjct: 278 PPRKDAAPALGPLSSSPLATPSPSAPPSPSAPPSL----QTLPSPPATPPSQATTSLGSP 333

Query: 534 VNQGVNSGVLQLSQPVVSGVLPVGQPVRPGVLQLNQTVGTNILPVNQPVRPGASQNTTFL 593
             Q  +S    L  P +S  L    P  P  L L         P+  P  P AS   + L
Sbjct: 334 TLQATHSF---LPSPPLSP-LATPPPQAPPALALP--------PLQAPPSPPASPPLSPL 381

Query: 594 TSGSILRQLIPTGKQVNGIPTYTL-APVS------VTLPVPPGGLATVAPPQMPIQLLPS 646
            +        P+ +  N +  + L AP S      V  P  P     V+P   P    P 
Sbjct: 382 AT--------PSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPP 433

Query: 647 GAAAPMAGSMPGMP-SPPVLVNA 668
             AAP     P  P SPP+  +A
Sbjct: 434 SLAAPPLQVPPSPPASPPMSPSA 456



 Score = 40.8 bits (94), Expect = 0.007
 Identities = 49/195 (25%), Positives = 70/195 (35%), Gaps = 30/195 (15%)

Query: 274 LAAPANGSAPSAPAQPPCFHLALPQ-NSPSPAAGQPVTVAQGAPGSLTHSPPAAGQSHMT 332
           LAAP     PS PA PP    A P   +P P A  P+ +A+  P     +PPA     + 
Sbjct: 435 LAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPP----QAPPALATPPLQ 490

Query: 333 LVSSPLPVGQNSLTLQPPAPQPVFLSHGVPLHQSVNPPVLPLSQPVGPVNKSVGTSVLPI 392
            + SP                P       P   S + P+ PL+ P       +   +L +
Sbjct: 491 ALPSP----------------PASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQV 534

Query: 393 NQTVRPGVLPLTQPVGPINRPVGPGVLPVSPSVTPGVLQAVSPGVLSVSRAVPSGVLPAG 452
                P   P +  +    RP  PG  P +    P +  A++PG        PS  L   
Sbjct: 535 -----PPSPPASPTLQAPRRPPTPG--PDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGP 587

Query: 453 QMTPAGQMTPAGVIP 467
            +  AG  + A   P
Sbjct: 588 DL--AGHSSSATSTP 600


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.317    0.134    0.408 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 51,493,764
Number of Sequences: 37866
Number of extensions: 2976762
Number of successful extensions: 17812
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 84
Number of HSP's successfully gapped in prelim test: 905
Number of HSP's that attempted gapping in prelim test: 13248
Number of HSP's gapped (non-prelim): 4358
length of query: 1131
length of database: 18,247,518
effective HSP length: 113
effective length of query: 1018
effective length of database: 13,968,660
effective search space: 14220095880
effective search space used: 14220095880
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 67 (30.4 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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