Guide to the Human Genome
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Search of human proteins with 7662342

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|7662342 zinc fingers and homeoboxes 2 [Homo sapiens]
         (837 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|7662342 zinc fingers and homeoboxes 2 [Homo sapiens]              1680   0.0  
gi|63079683 zinc fingers and homeoboxes 1 [Homo sapiens]              559   e-159
gi|63079680 zinc fingers and homeoboxes 1 [Homo sapiens]              559   e-159
gi|28827782 zinc fingers and homeoboxes 3 [Homo sapiens]              436   e-122
gi|158631177 homeodomain leucine zipper protein [Homo sapiens]         76   1e-13
gi|239751129 PREDICTED: hypothetical protein XP_002347726 [Homo ...    52   3e-06
gi|239745620 PREDICTED: hypothetical protein XP_002344158 [Homo ...    52   3e-06
gi|118498345 AT-binding transcription factor 1 [Homo sapiens]          50   7e-06
gi|126090663 zinc finger homeodomain 4 [Homo sapiens]                  46   2e-04
gi|23943886 Rhox homeobox family, member 1 [Homo sapiens]              46   2e-04
gi|189181724 proteoglycan 4 isoform D [Homo sapiens]                   45   3e-04
gi|189181722 proteoglycan 4 isoform C [Homo sapiens]                   45   3e-04
gi|189181720 proteoglycan 4 isoform B [Homo sapiens]                   45   3e-04
gi|67190163 proteoglycan 4 isoform A [Homo sapiens]                    45   3e-04
gi|21956641 ISL LIM homeobox 2 [Homo sapiens]                          45   4e-04
gi|138175817 zinc finger protein 236 [Homo sapiens]                    44   5e-04
gi|61969662 double homeobox A [Homo sapiens]                           44   6e-04
gi|4557489 cone-rod homeobox protein [Homo sapiens]                    44   8e-04
gi|21361183 paired-like homeodomain transcription factor 2 isofo...    43   0.001
gi|239744249 PREDICTED: similar to double homeobox, 4 [Homo sapi...    43   0.001
gi|239744248 PREDICTED: similar to double homeobox, 4 [Homo sapi...    43   0.001
gi|239744246 PREDICTED: hypothetical protein XP_002343082 [Homo ...    43   0.001
gi|239744242 PREDICTED: similar to double homeobox, 4 [Homo sapi...    43   0.001
gi|239744240 PREDICTED: similar to double homeobox, 4 [Homo sapi...    43   0.001
gi|239742468 PREDICTED: double homeobox, 4-like [Homo sapiens]         43   0.001
gi|239742467 PREDICTED: double homeobox, 4-like [Homo sapiens]         43   0.001
gi|194272172 double homeobox, 4 [Homo sapiens]                         43   0.001
gi|194272217 double homeobox, 4-like [Homo sapiens]                    43   0.001
gi|194272216 double homeobox, 4-like [Homo sapiens]                    43   0.001
gi|194272215 double homeobox, 4-like [Homo sapiens]                    43   0.001

>gi|7662342 zinc fingers and homeoboxes 2 [Homo sapiens]
          Length = 837

 Score = 1680 bits (4351), Expect = 0.0
 Identities = 837/837 (100%), Positives = 837/837 (100%)

Query: 1   MASKRKSTTPCMVRTSQVVEQDVPEEVDRAKEKGIGTPQPDVAKDSWAAELENSSKENEV 60
           MASKRKSTTPCMVRTSQVVEQDVPEEVDRAKEKGIGTPQPDVAKDSWAAELENSSKENEV
Sbjct: 1   MASKRKSTTPCMVRTSQVVEQDVPEEVDRAKEKGIGTPQPDVAKDSWAAELENSSKENEV 60

Query: 61  IEVKSMGESQSKKLQGGYECKYCPYSTQNLNEFTEHVDMQHPNVILNPLYVCAECNFTTK 120
           IEVKSMGESQSKKLQGGYECKYCPYSTQNLNEFTEHVDMQHPNVILNPLYVCAECNFTTK
Sbjct: 61  IEVKSMGESQSKKLQGGYECKYCPYSTQNLNEFTEHVDMQHPNVILNPLYVCAECNFTTK 120

Query: 121 KYDSLSDHNSKFHPGEANFKLKLIKRNNQTVLEQSIETTNHVVSITTSGPGTGDSDSGIS 180
           KYDSLSDHNSKFHPGEANFKLKLIKRNNQTVLEQSIETTNHVVSITTSGPGTGDSDSGIS
Sbjct: 121 KYDSLSDHNSKFHPGEANFKLKLIKRNNQTVLEQSIETTNHVVSITTSGPGTGDSDSGIS 180

Query: 181 VSKTPIMKPGKPKADAKKVPKKPEEITPENHVEGTARLVTDTAEILSRLGGVELLQDTLG 240
           VSKTPIMKPGKPKADAKKVPKKPEEITPENHVEGTARLVTDTAEILSRLGGVELLQDTLG
Sbjct: 181 VSKTPIMKPGKPKADAKKVPKKPEEITPENHVEGTARLVTDTAEILSRLGGVELLQDTLG 240

Query: 241 HVMPSVQLPPNINLVPKVPVPLNTTKYNSALDTNATMINSFNKFPYPTQAELSWLTAASK 300
           HVMPSVQLPPNINLVPKVPVPLNTTKYNSALDTNATMINSFNKFPYPTQAELSWLTAASK
Sbjct: 241 HVMPSVQLPPNINLVPKVPVPLNTTKYNSALDTNATMINSFNKFPYPTQAELSWLTAASK 300

Query: 301 HPEEHIRIWFATQRLKHGISWSPEEVEEARKKMFNGTIQSVPPTITVLPAQLAPTKVTQP 360
           HPEEHIRIWFATQRLKHGISWSPEEVEEARKKMFNGTIQSVPPTITVLPAQLAPTKVTQP
Sbjct: 301 HPEEHIRIWFATQRLKHGISWSPEEVEEARKKMFNGTIQSVPPTITVLPAQLAPTKVTQP 360

Query: 361 ILQTALPCQILGQTSLVLTQVTSGSTTVSCSPITLAVAGVTNHGQKRPLVTPQAAPEPKR 420
           ILQTALPCQILGQTSLVLTQVTSGSTTVSCSPITLAVAGVTNHGQKRPLVTPQAAPEPKR
Sbjct: 361 ILQTALPCQILGQTSLVLTQVTSGSTTVSCSPITLAVAGVTNHGQKRPLVTPQAAPEPKR 420

Query: 421 PHIAQVPEPPPKVANPPLTPASDRKKTKEQIAHLKASFLQSQFPDDAEVYRLIEVTGLAR 480
           PHIAQVPEPPPKVANPPLTPASDRKKTKEQIAHLKASFLQSQFPDDAEVYRLIEVTGLAR
Sbjct: 421 PHIAQVPEPPPKVANPPLTPASDRKKTKEQIAHLKASFLQSQFPDDAEVYRLIEVTGLAR 480

Query: 481 SEIKKWFSDHRYRCQRGIVHITSESLAKDQLAIAASRHGRTYHAYPDFAPQKFKEKTQGQ 540
           SEIKKWFSDHRYRCQRGIVHITSESLAKDQLAIAASRHGRTYHAYPDFAPQKFKEKTQGQ
Sbjct: 481 SEIKKWFSDHRYRCQRGIVHITSESLAKDQLAIAASRHGRTYHAYPDFAPQKFKEKTQGQ 540

Query: 541 VKILEDSFLKSSFPTQAELDRLRVETKLSRREIDSWFSERRKLRDSMEQAVLDSMGSGKK 600
           VKILEDSFLKSSFPTQAELDRLRVETKLSRREIDSWFSERRKLRDSMEQAVLDSMGSGKK
Sbjct: 541 VKILEDSFLKSSFPTQAELDRLRVETKLSRREIDSWFSERRKLRDSMEQAVLDSMGSGKK 600

Query: 601 GQDVGAPNGALSRLDQLSGAQLTSSLPSPSPAIAKSQEQVHLLRSTFARTQWPTPQEYDQ 660
           GQDVGAPNGALSRLDQLSGAQLTSSLPSPSPAIAKSQEQVHLLRSTFARTQWPTPQEYDQ
Sbjct: 601 GQDVGAPNGALSRLDQLSGAQLTSSLPSPSPAIAKSQEQVHLLRSTFARTQWPTPQEYDQ 660

Query: 661 LAAKTGLVRTEIVRWFKENRCLLKTGTVKWMEQYQHQPMADDHGYDAVARKATKPMAESP 720
           LAAKTGLVRTEIVRWFKENRCLLKTGTVKWMEQYQHQPMADDHGYDAVARKATKPMAESP
Sbjct: 661 LAAKTGLVRTEIVRWFKENRCLLKTGTVKWMEQYQHQPMADDHGYDAVARKATKPMAESP 720

Query: 721 KNGGDVVPQYYKDPKKLCEEDLEKLVTRVKVGSEPAKDCLPAKPSEATSDRSEGSSRDGQ 780
           KNGGDVVPQYYKDPKKLCEEDLEKLVTRVKVGSEPAKDCLPAKPSEATSDRSEGSSRDGQ
Sbjct: 721 KNGGDVVPQYYKDPKKLCEEDLEKLVTRVKVGSEPAKDCLPAKPSEATSDRSEGSSRDGQ 780

Query: 781 GSDENEESSVVDYVEVTVGEEDAISDRSDSWSQAAAEGVSELAESDSDCVPAEAGQA 837
           GSDENEESSVVDYVEVTVGEEDAISDRSDSWSQAAAEGVSELAESDSDCVPAEAGQA
Sbjct: 781 GSDENEESSVVDYVEVTVGEEDAISDRSDSWSQAAAEGVSELAESDSDCVPAEAGQA 837


>gi|63079683 zinc fingers and homeoboxes 1 [Homo sapiens]
          Length = 873

 Score =  559 bits (1441), Expect = e-159
 Identities = 347/889 (39%), Positives = 492/889 (55%), Gaps = 109/889 (12%)

Query: 1   MASKRKSTTPCMVRTSQVVEQDVPEEVDRAKEKGIGTPQPDVAKDSWAAELENSSKENEV 60
           MAS+RKSTTPCMV  S   EQD   E+    ++G     P V         E+ S + EV
Sbjct: 1   MASRRKSTTPCMVLAS---EQDPDLELISDLDEG-----PPVLTPVENTRAESISSDEEV 52

Query: 61  IEVKSMGESQSKKLQGGYECKYCPYSTQNLNEFTEHVDMQHPNVILNPLYVCAECNFTTK 120
            E       Q+KK++GGYECKYC + T +LN FT HVD +HPNV+LN  YVC ECNF TK
Sbjct: 53  HESVDSDNQQNKKVEGGYECKYCTFQTPDLNMFTFHVDSEHPNVVLNSSYVCVECNFLTK 112

Query: 121 KYDSLSDHNSKFHPGEANFKLKLIKRNNQTVLEQSIETTNHVVSI-----TTSGPGTGDS 175
           +YD+LS+HN K+HPGE NFKL ++KRNNQT+ EQ+I       S            T  S
Sbjct: 113 RYDALSEHNLKYHPGEENFKLTMVKRNNQTIFEQTINDLTFDGSFVKEENAEQAESTEVS 172

Query: 176 DSGISVSKTPIMKPGKPKADAKKV-----------PKKPEEITP------ENHVEGTARL 218
            SGIS+SKTPIMK  K K + K++            +K  EI P      EN     +  
Sbjct: 173 SSGISISKTPIMKMMKNKVENKRIAVHHNSVEDVPEEKENEIKPDREEIVENPSSSASES 232

Query: 219 VTDTAEI-------LSRLGGVELLQDTLGHVMPSVQLPPNINLVPKVPVPLNT-TKYNSA 270
            T T+ +        S +     +   L  V+ +V    N NL+PKV +P+N+   YN+A
Sbjct: 233 NTSTSIVNRIHPSTASTVVTPAAVLPGLAQVITAVSAQQNSNLIPKVLIPVNSIPTYNAA 292

Query: 271 LDTNATMINSFNKFPYPTQAELSWLTAASKHPEEHIRIWFATQRLKHGISWSPEEVEEAR 330
           LD N  ++N++NKFPYPT +E++ L+A +K+ EE I+IWF+ QRLKHG+SW+PEEVEEAR
Sbjct: 293 LDNNPLLLNTYNKFPYPTMSEITVLSAQAKYTEEQIKIWFSAQRLKHGVSWTPEEVEEAR 352

Query: 331 KKMFNGTIQSVPPTITVLPAQLAPTKVTQP-ILQTALPCQILGQTSLVLTQVTSGSTTVS 389
           +K FNGT+ +VP TITV+P  ++      P ILQT   CQI+GQ  LVLTQV   +T   
Sbjct: 353 RKQFNGTVHTVPQTITVIPTHISTGSNGLPSILQT---CQIVGQPGLVLTQVAGTNTLPV 409

Query: 390 CSPITLAVAGVTNHGQKRPLVTPQAAPEPK-RPHIAQVP-EPPPKVANPPLTPAS---DR 444
            +PI L VAGV +    +    P A P  + +P  A VP     K     + P S     
Sbjct: 410 TAPIALTVAGVPSQNNIQKSQVPAAQPTAETKPATAAVPTSQSVKHETALVNPDSFGIRA 469

Query: 445 KKTKEQIAHLKASFLQSQFPDDAEVYRLIEVTGLARSEIKKWFSDHRYRCQRG----IVH 500
           KKTKEQ+A LK S+L++QFP D+E+ RL+++TGL + EIKKWFSD RY  +       +H
Sbjct: 470 KKTKEQLAELKVSYLKNQFPHDSEIIRLMKITGLTKGEIKKWFSDTRYNQRNSKSNQCLH 529

Query: 501 ITSESL----------AKDQLAIAASRHGRTYHAYPDFAPQKFKEKTQGQVKILEDSFLK 550
           + ++S             +   +  ++  ++++ +PDF PQKFKEKT  Q+++L+ SFL 
Sbjct: 530 LNNDSSTTIIIDSSDETTESPTVGTAQPKQSWNPFPDFTPQKFKEKTAEQLRVLQASFLN 589

Query: 551 SSFPTQAELDRLRVETKLSRREIDSWFSERRKLRDSMEQAV-LDSMGSGKKGQDVGAPNG 609
           SS  T  EL+RLR +TKL+RREID+WF+E++K +   E+ + +D   +G   ++ G  + 
Sbjct: 590 SSVLTDEELNRLRAQTKLTRREIDAWFTEKKKSKALKEEKMEIDESNAGSSKEEAGETSP 649

Query: 610 ALSRLDQLSGAQLTSSLPSPSPAIAKSQEQVHLLRSTFARTQWPTPQEYDQLAAKTGLVR 669
           A       SGA  +    S      K+ EQ+H+L+S F RTQWP+P+EYD+LA ++GL R
Sbjct: 650 A-----DESGAPKSG---STGKICKKTPEQLHMLKSAFVRTQWPSPEEYDKLAKESGLAR 701

Query: 670 TEIVRWFKENRCLLKTGTVKWMEQYQHQPMADDHGYDAVARKA----------------- 712
           T+IV WF + R   K G +KW   YQ    +  +G  ++ ++                  
Sbjct: 702 TDIVSWFGDTRYAWKNGNLKWYYYYQSANSSSMNGLSSLRKRGRGRPKGRGRGRPRGRPR 761

Query: 713 ---------TKPMAESPKNGGDVVPQYYKDPKKLCEEDLEKLVTRVKVGSEPAKDCLPAK 763
                      P     K G  ++  YY   K L E+DL++LV +  +G E  +      
Sbjct: 762 GSKRINNWDRGPSLIKFKTGTAILKDYYLKHKFLNEQDLDELVNKSHMGYEQVR------ 815

Query: 764 PSEATSDRSEGSSRDGQGSDEN-EESSVVDYVEVTVGEEDAISDRSDSW 811
             E  ++R   S    +  +EN EE  V+D  E    E++  +D SD+W
Sbjct: 816 --EWFAERQRRSELGIELFEENEEEDEVIDDQE----EDEEETDDSDTW 858


>gi|63079680 zinc fingers and homeoboxes 1 [Homo sapiens]
          Length = 873

 Score =  559 bits (1441), Expect = e-159
 Identities = 347/889 (39%), Positives = 492/889 (55%), Gaps = 109/889 (12%)

Query: 1   MASKRKSTTPCMVRTSQVVEQDVPEEVDRAKEKGIGTPQPDVAKDSWAAELENSSKENEV 60
           MAS+RKSTTPCMV  S   EQD   E+    ++G     P V         E+ S + EV
Sbjct: 1   MASRRKSTTPCMVLAS---EQDPDLELISDLDEG-----PPVLTPVENTRAESISSDEEV 52

Query: 61  IEVKSMGESQSKKLQGGYECKYCPYSTQNLNEFTEHVDMQHPNVILNPLYVCAECNFTTK 120
            E       Q+KK++GGYECKYC + T +LN FT HVD +HPNV+LN  YVC ECNF TK
Sbjct: 53  HESVDSDNQQNKKVEGGYECKYCTFQTPDLNMFTFHVDSEHPNVVLNSSYVCVECNFLTK 112

Query: 121 KYDSLSDHNSKFHPGEANFKLKLIKRNNQTVLEQSIETTNHVVSI-----TTSGPGTGDS 175
           +YD+LS+HN K+HPGE NFKL ++KRNNQT+ EQ+I       S            T  S
Sbjct: 113 RYDALSEHNLKYHPGEENFKLTMVKRNNQTIFEQTINDLTFDGSFVKEENAEQAESTEVS 172

Query: 176 DSGISVSKTPIMKPGKPKADAKKV-----------PKKPEEITP------ENHVEGTARL 218
            SGIS+SKTPIMK  K K + K++            +K  EI P      EN     +  
Sbjct: 173 SSGISISKTPIMKMMKNKVENKRIAVHHNSVEDVPEEKENEIKPDREEIVENPSSSASES 232

Query: 219 VTDTAEI-------LSRLGGVELLQDTLGHVMPSVQLPPNINLVPKVPVPLNT-TKYNSA 270
            T T+ +        S +     +   L  V+ +V    N NL+PKV +P+N+   YN+A
Sbjct: 233 NTSTSIVNRIHPSTASTVVTPAAVLPGLAQVITAVSAQQNSNLIPKVLIPVNSIPTYNAA 292

Query: 271 LDTNATMINSFNKFPYPTQAELSWLTAASKHPEEHIRIWFATQRLKHGISWSPEEVEEAR 330
           LD N  ++N++NKFPYPT +E++ L+A +K+ EE I+IWF+ QRLKHG+SW+PEEVEEAR
Sbjct: 293 LDNNPLLLNTYNKFPYPTMSEITVLSAQAKYTEEQIKIWFSAQRLKHGVSWTPEEVEEAR 352

Query: 331 KKMFNGTIQSVPPTITVLPAQLAPTKVTQP-ILQTALPCQILGQTSLVLTQVTSGSTTVS 389
           +K FNGT+ +VP TITV+P  ++      P ILQT   CQI+GQ  LVLTQV   +T   
Sbjct: 353 RKQFNGTVHTVPQTITVIPTHISTGSNGLPSILQT---CQIVGQPGLVLTQVAGTNTLPV 409

Query: 390 CSPITLAVAGVTNHGQKRPLVTPQAAPEPK-RPHIAQVP-EPPPKVANPPLTPAS---DR 444
            +PI L VAGV +    +    P A P  + +P  A VP     K     + P S     
Sbjct: 410 TAPIALTVAGVPSQNNIQKSQVPAAQPTAETKPATAAVPTSQSVKHETALVNPDSFGIRA 469

Query: 445 KKTKEQIAHLKASFLQSQFPDDAEVYRLIEVTGLARSEIKKWFSDHRYRCQRG----IVH 500
           KKTKEQ+A LK S+L++QFP D+E+ RL+++TGL + EIKKWFSD RY  +       +H
Sbjct: 470 KKTKEQLAELKVSYLKNQFPHDSEIIRLMKITGLTKGEIKKWFSDTRYNQRNSKSNQCLH 529

Query: 501 ITSESL----------AKDQLAIAASRHGRTYHAYPDFAPQKFKEKTQGQVKILEDSFLK 550
           + ++S             +   +  ++  ++++ +PDF PQKFKEKT  Q+++L+ SFL 
Sbjct: 530 LNNDSSTTIIIDSSDETTESPTVGTAQPKQSWNPFPDFTPQKFKEKTAEQLRVLQASFLN 589

Query: 551 SSFPTQAELDRLRVETKLSRREIDSWFSERRKLRDSMEQAV-LDSMGSGKKGQDVGAPNG 609
           SS  T  EL+RLR +TKL+RREID+WF+E++K +   E+ + +D   +G   ++ G  + 
Sbjct: 590 SSVLTDEELNRLRAQTKLTRREIDAWFTEKKKSKALKEEKMEIDESNAGSSKEEAGETSP 649

Query: 610 ALSRLDQLSGAQLTSSLPSPSPAIAKSQEQVHLLRSTFARTQWPTPQEYDQLAAKTGLVR 669
           A       SGA  +    S      K+ EQ+H+L+S F RTQWP+P+EYD+LA ++GL R
Sbjct: 650 A-----DESGAPKSG---STGKICKKTPEQLHMLKSAFVRTQWPSPEEYDKLAKESGLAR 701

Query: 670 TEIVRWFKENRCLLKTGTVKWMEQYQHQPMADDHGYDAVARKA----------------- 712
           T+IV WF + R   K G +KW   YQ    +  +G  ++ ++                  
Sbjct: 702 TDIVSWFGDTRYAWKNGNLKWYYYYQSANSSSMNGLSSLRKRGRGRPKGRGRGRPRGRPR 761

Query: 713 ---------TKPMAESPKNGGDVVPQYYKDPKKLCEEDLEKLVTRVKVGSEPAKDCLPAK 763
                      P     K G  ++  YY   K L E+DL++LV +  +G E  +      
Sbjct: 762 GSKRINNWDRGPSLIKFKTGTAILKDYYLKHKFLNEQDLDELVNKSHMGYEQVR------ 815

Query: 764 PSEATSDRSEGSSRDGQGSDEN-EESSVVDYVEVTVGEEDAISDRSDSW 811
             E  ++R   S    +  +EN EE  V+D  E    E++  +D SD+W
Sbjct: 816 --EWFAERQRRSELGIELFEENEEEDEVIDDQE----EDEEETDDSDTW 858


>gi|28827782 zinc fingers and homeoboxes 3 [Homo sapiens]
          Length = 956

 Score =  436 bits (1120), Expect = e-122
 Identities = 316/965 (32%), Positives = 455/965 (47%), Gaps = 157/965 (16%)

Query: 1   MASKRKSTTPCMVRTSQVVEQDVPEEVDRAKEKGIGTPQPDVAKDSWAAELENSSKENEV 60
           MASKRKSTTPCM+    VV QD   E   A+    G PQ D+  ++ AA  E +   +  
Sbjct: 1   MASKRKSTTPCMIPVKTVVLQDASMEAQPAETLPEG-PQQDLPPEASAASSEAAQNPSST 59

Query: 61  IEVKSMGESQSKKLQGG-YECKYCPYSTQNLNEFTEHVDMQHPNVILNPLYVCAECNFTT 119
            +  ++       L G  Y CKYC + + ++ +F  H++ +H +   +P +VC+ C+F  
Sbjct: 60  -DGSTLANGHRSTLDGYLYSCKYCDFRSHDMTQFVGHMNSEHTDFNKDPTFVCSGCSFLA 118

Query: 120 KKYDSLSDHNSKFHPGEANFKLKLIKRNNQTVLEQSIETTNHVVSITTSGPGTG-DSDSG 178
           K  + LS HN+  H GEA+F   + K +N  V+EQSI  +     +       G D  + 
Sbjct: 119 KTPEGLSLHNATCHSGEASFVWNVAKPDNHVVVEQSIPESTSTPDLAGEPSAEGADGQAE 178

Query: 179 ISVSKTPIMKPGKPKADAKKVPKKPEEITPENHVEGTARLVTDTAEILS----------- 227
           I ++KTPIMK  K KA+AKK+    E +  +   E   +L T   E+             
Sbjct: 179 IIITKTPIMKIMKGKAEAKKIHTLKENVPSQPVGEALPKLSTGEMEVREGDHSFINGAVP 238

Query: 228 ------------------RLGGVELLQDTLGHVMPSVQLP------------PNINLVPK 257
                              +G V +L   +   +   Q P            P    +PK
Sbjct: 239 VSQASASSAKNPHAANGPLIGTVPVLPAGIAQFLSLQQQPPVHAQHHVHQPLPTAKALPK 298

Query: 258 VPVPLNT-TKYNSALDTNATMINSFNKFPYPTQAELSWLTAASKHPEEHIRIWFATQRLK 316
           V +PL++   YN+A+D+N+ + NSF+KFPYPT+AEL +LT  +K+PEE ++IWF  QRLK
Sbjct: 299 VMIPLSSIPTYNAAMDSNSFLKNSFHKFPYPTKAELCYLTVVTKYPEEQLKIWFTAQRLK 358

Query: 317 HGISWSPEEVEEARKKMFNGTIQSVP-PTITVLPAQL-APTKVTQPILQTALPCQILGQT 374
            GISWSPEE+E+ARKKMFN  IQSVP PTITVL   L A     Q ++Q ALP  ++GQ 
Sbjct: 359 QGISWSPEEIEDARKKMFNTVIQSVPQPTITVLNTPLVASAGNVQHLIQAALPGHVVGQP 418

Query: 375 S------LVLTQVTSGSTTVSCSPITLAVAGVTNHGQKRPL--VTPQAAPEPKRPHIAQ- 425
                  LV   + +     + SP+ L V  V       P+  V        K  + AQ 
Sbjct: 419 EGTGGGLLVTQPLMANGLQATSSPLPLTVTSVPKQPGVAPINTVCSNTTSAVKVVNAAQS 478

Query: 426 VPEPPPKVANPPLTPAS--DRKKTKEQIAHLKASFLQSQFPDDAEVYRLIEVTGLARSEI 483
           +    P + +     AS    KK+ EQ++ LK SF ++QFP  +EV  L +VTGL+  E+
Sbjct: 479 LLTACPSITSQAFLDASIYKNKKSHEQLSALKGSFCRNQFPGQSEVEHLTKVTGLSTREV 538

Query: 484 KKWFSDHRYRCQ-----RGIVHITSESLAKDQ-----------------------LAIAA 515
           +KWFSD RY C+     R ++     S+  D                        LA   
Sbjct: 539 RKWFSDRRYHCRNLKGSRAMIPGDHSSIIIDSVPEVSFSPSSKVPEVTCIPTTATLATHP 598

Query: 516 SRHGRTYHAYPDFAPQKFKEKTQGQVKILEDSFLKSSFPTQAELDRLRVETKLSRREIDS 575
           S   +++H  PDF P K+KE+   Q++ LE SF ++  P   ELDRLR ETK++RREIDS
Sbjct: 599 SAKRQSWHQTPDFTPTKYKERAPEQLRALESSFAQNPLPLDEELDRLRSETKMTRREIDS 658

Query: 576 WFSERRK-------------LRDSMEQAVLDSMGSGKKGQD--VGAPNGALS-------- 612
           WFSERRK                  E+A  D  G      +  V   NG+L         
Sbjct: 659 WFSERRKKVNAEETKKAEENASQEEEEAAEDEGGEEDLASELRVSGENGSLEMPSSHILA 718

Query: 613 --------------RLDQLSGAQLTSSLPSPSP----------------AIAKSQEQVHL 642
                         R+ + +G      L +  P                +  K+ +Q HL
Sbjct: 719 ERKVSPIKINLKNLRVTEANGRNEIPGLGACDPEDDESNKLAEQLPGKVSCKKTAQQRHL 778

Query: 643 LRSTFARTQWPTPQEYDQLAAKTGLVRTEIVRWFKENRCLLKTGTVKWMEQYQHQPMADD 702
           LR  F +TQWP+ Q+YD + A+TGL R E+VRWF ++R  LK G +KW E Y+       
Sbjct: 779 LRQLFVQTQWPSNQDYDSIMAQTGLPRPEVVRWFGDSRYALKNGQLKWYEDYKRGNFPP- 837

Query: 703 HGYDAVARKATKPMAESPKNGGDVVPQYYKDPKKLCEEDLEKLVTRVKVGSEPAKDCLPA 762
            G   +A          P N  +++  YY   K L EEDL+ L  + ++ S+  K     
Sbjct: 838 -GLLVIA----------PGN-RELLQDYYMTHKMLYEEDLQNLCDKTQMSSQQVKQWFAE 885

Query: 763 KPSEATSDRSEGSSRDGQGSDENEESSVVDYVEVTVGEEDAISDRSDSWSQAAAEGVSEL 822
           K  E T   ++  S D QG    E ++V   +  T  E   +S+ S+SW     E  SE 
Sbjct: 886 KMGEETRAVADTGSED-QGPGTGELTAVHKGMGDTYSE---VSENSESWEPRVPEASSEP 941

Query: 823 AESDS 827
            ++ S
Sbjct: 942 FDTSS 946


>gi|158631177 homeodomain leucine zipper protein [Homo sapiens]
          Length = 550

 Score = 75.9 bits (185), Expect = 1e-13
 Identities = 110/453 (24%), Positives = 170/453 (37%), Gaps = 60/453 (13%)

Query: 269 SALDTNATMINSFNKFPYPTQAELSWLTAASKHPEEHIRIWFATQRLKHGISWSPEEVEE 328
           S LD+N  ++ +F+ FPYP+ A+++ L        E ++ WF  QRL+ GISWS EE+EE
Sbjct: 62  SELDSNEHLLKTFSYFPYPSLADIALLCLRYGLQMEKVKTWFMAQRLRCGISWSSEEIEE 121

Query: 329 ARKKM--------FNGTI----------QSVPPTITVLPAQ----LAPTKVTQPILQTAL 366
            R ++        F   +          + VPP     P Q    + P  +++P     L
Sbjct: 122 TRARVVYRRDQLHFKSLLSFTHHAGRPPEEVPPPPVPAPEQVGIGIGPPTLSKPTQTKGL 181

Query: 367 ------PCQI--LGQTSLVLTQ--VTSGSTTVSCSPITLAVAGVTNHGQKRPLVTPQAAP 416
                 P Q+  L Q+   L +  +T GS            +    H Q   L   QA  
Sbjct: 182 KVEPEEPSQMPPLPQSHQKLKESLMTPGSGAFPYQ------SDFWQHLQSSGLSKEQAGR 235

Query: 417 EPKRP---------HIAQVPEPPPKVANPPLT-PASDRKKTKEQIAHLKASFLQSQFPDD 466
            P +          H   VP+P  +   PP+   AS  K+         +S   S F   
Sbjct: 236 GPNQSHGIGTASWNHSTTVPQPQARDKPPPIALIASSCKEESASSVTPSSSSTSSSFQVL 295

Query: 467 AEVYRLIEVTGLARSEIKKWFSDHRYRCQRGIVHITSESLAKDQLAIAASRHGRTYHAYP 526
           A               + +  S         +     + L  + +     R G T +  P
Sbjct: 296 ANGATAASKPLQPLGCVPQSVSPSEQALPPHLEPAWPQGLRHNSV---PGRVGPTEYLSP 352

Query: 527 DFAPQ-KFKEKTQGQVKILEDSFLKSSFPTQAELDRLRVETKLSRREIDSWFSERR-KLR 584
           D   Q K K KT+ Q+ IL+  FL+  +  + +  +L   T L R EI  WF + R  L+
Sbjct: 353 DMQRQRKTKRKTKEQLAILKSFFLQCQWARREDYQKLEQITGLPRPEIIQWFGDTRYALK 412

Query: 585 DSMEQAVLDSMGSGKKG-QDVGAPNGALSRLDQLSGAQLTSSLPSPSPAIAKSQEQVHLL 643
               +   D+   G    QD   P    S       A+ T  LP P P        +  L
Sbjct: 413 HGQLKWFRDNAVPGAPSFQDPAIPTPPPSTRSLNERAE-TPPLPIPPP-----PPDIQPL 466

Query: 644 RSTFARTQWPTPQEYDQLAAKTGLVRTEIVRWF 676
              +A  Q     +  QL+  + L   +++ WF
Sbjct: 467 ERYWAAHQQLRETDIPQLSQASRLSTQQVLDWF 499



 Score = 60.8 bits (146), Expect = 5e-09
 Identities = 50/189 (26%), Positives = 82/189 (43%), Gaps = 20/189 (10%)

Query: 635 KSQEQVHLLRSTFARTQWPTPQEYDQLAAKTGLVRTEIVRWFKENRCLLKTGTVKWMEQ- 693
           K++EQ+ +L+S F + QW   ++Y +L   TGL R EI++WF + R  LK G +KW    
Sbjct: 363 KTKEQLAILKSFFLQCQWARREDYQKLEQITGLPRPEIIQWFGDTRYALKHGQLKWFRDN 422

Query: 694 -YQHQPMADDHGYD-------AVARKATKPMAESPKNGGDVVP--QYYKDPKKLCEEDLE 743
                P   D           ++  +A  P    P    D+ P  +Y+   ++L E D+ 
Sbjct: 423 AVPGAPSFQDPAIPTPPPSTRSLNERAETPPLPIPPPPPDIQPLERYWAAHQQLRETDIP 482

Query: 744 KLVTRVKVGSEPAKDCLPAK---PSEATSDRSEGSSRDGQGSDENEESSVVDYVEVTVGE 800
           +L    ++ ++   D   ++   P+E           D +  +E EE    D  E    E
Sbjct: 483 QLSQASRLSTQQVLDWFDSRLPQPAEVV------VCLDEEEEEEEEELPEDDEEEEEEEE 536

Query: 801 EDAISDRSD 809
           ED   D  D
Sbjct: 537 EDDDDDDDD 545


>gi|239751129 PREDICTED: hypothetical protein XP_002347726 [Homo
           sapiens]
          Length = 345

 Score = 51.6 bits (122), Expect = 3e-06
 Identities = 37/134 (27%), Positives = 63/134 (47%), Gaps = 11/134 (8%)

Query: 454 LKASFLQSQFPDDAEVYRLIEVTGLARSEIKKWFSDHRYRCQRGIVHITSESLAKDQLAI 513
           L++ F    FPD A   +L +  G+  S I+ WF ++R + ++      SE   KDQ   
Sbjct: 30  LQSWFQHDPFPDKAAREQLAKEIGVPESNIQVWFKNYRVKQRKLDYKCFSE---KDQ--- 83

Query: 514 AASRHGRTYHAYPDFAPQKFKEK----TQGQVKILEDSFLKSSFPTQAELDRLRVETKLS 569
               H ++ H   ++ P++ ++K    T  Q   L  +F ++ FP  A   +L  +T L 
Sbjct: 84  -TQGHDQSQHLTQEYLPKEARQKQTFITWTQKNRLVQAFERNPFPDIATRKKLAEQTGLQ 142

Query: 570 RREIDSWFSERRKL 583
              I  WF ++R L
Sbjct: 143 ESRIQMWFQKQRSL 156



 Score = 40.0 bits (92), Expect = 0.009
 Identities = 38/145 (26%), Positives = 56/145 (38%), Gaps = 12/145 (8%)

Query: 538 QGQVKILEDSFLKSSFPTQAELDRLRVETKLSRREIDSWFSERRKLRDSMEQAVLDSMGS 597
           Q Q  IL+  F    FP +A  ++L  E  +    I  WF   R     ++Q  LD    
Sbjct: 24  QSQKDILQSWFQHDPFPDKAAREQLAKEIGVPESNIQVWFKNYR-----VKQRKLDYKCF 78

Query: 598 GKKGQDVGAPNGALSRLDQLSGAQLTSSLPSPSPAIAKSQEQVHLLRSTFARTQWPTPQE 657
            +K Q  G           L+   L          I  +Q+  + L   F R  +P    
Sbjct: 79  SEKDQTQGHDQS-----QHLTQEYLPKEARQKQTFITWTQK--NRLVQAFERNPFPDIAT 131

Query: 658 YDQLAAKTGLVRTEIVRWFKENRCL 682
             +LA +TGL  + I  WF++ R L
Sbjct: 132 RKKLAEQTGLQESRIQMWFQKQRSL 156



 Score = 32.3 bits (72), Expect = 1.9
 Identities = 18/45 (40%), Positives = 23/45 (51%)

Query: 447 TKEQIAHLKASFLQSQFPDDAEVYRLIEVTGLARSEIKKWFSDHR 491
           T  Q   L  +F ++ FPD A   +L E TGL  S I+ WF   R
Sbjct: 110 TWTQKNRLVQAFERNPFPDIATRKKLAEQTGLQESRIQMWFQKQR 154



 Score = 30.4 bits (67), Expect = 7.1
 Identities = 16/48 (33%), Positives = 24/48 (50%)

Query: 633 IAKSQEQVHLLRSTFARTQWPTPQEYDQLAAKTGLVRTEIVRWFKENR 680
           I  +Q Q  +L+S F    +P     +QLA + G+  + I  WFK  R
Sbjct: 20  IQYNQSQKDILQSWFQHDPFPDKAAREQLAKEIGVPESNIQVWFKNYR 67


>gi|239745620 PREDICTED: hypothetical protein XP_002344158 [Homo
           sapiens]
          Length = 345

 Score = 51.6 bits (122), Expect = 3e-06
 Identities = 37/134 (27%), Positives = 63/134 (47%), Gaps = 11/134 (8%)

Query: 454 LKASFLQSQFPDDAEVYRLIEVTGLARSEIKKWFSDHRYRCQRGIVHITSESLAKDQLAI 513
           L++ F    FPD A   +L +  G+  S I+ WF ++R + ++      SE   KDQ   
Sbjct: 30  LQSWFQHDPFPDKAAREQLAKEIGVPESNIQVWFKNYRVKQRKLDYKCFSE---KDQ--- 83

Query: 514 AASRHGRTYHAYPDFAPQKFKEK----TQGQVKILEDSFLKSSFPTQAELDRLRVETKLS 569
               H ++ H   ++ P++ ++K    T  Q   L  +F ++ FP  A   +L  +T L 
Sbjct: 84  -TQGHDQSQHLTQEYLPKEARQKQTFITWTQKNRLVQAFERNPFPDIATRKKLAEQTGLQ 142

Query: 570 RREIDSWFSERRKL 583
              I  WF ++R L
Sbjct: 143 ESRIQMWFQKQRSL 156



 Score = 40.0 bits (92), Expect = 0.009
 Identities = 38/145 (26%), Positives = 56/145 (38%), Gaps = 12/145 (8%)

Query: 538 QGQVKILEDSFLKSSFPTQAELDRLRVETKLSRREIDSWFSERRKLRDSMEQAVLDSMGS 597
           Q Q  IL+  F    FP +A  ++L  E  +    I  WF   R     ++Q  LD    
Sbjct: 24  QSQKDILQSWFQHDPFPDKAAREQLAKEIGVPESNIQVWFKNYR-----VKQRKLDYKCF 78

Query: 598 GKKGQDVGAPNGALSRLDQLSGAQLTSSLPSPSPAIAKSQEQVHLLRSTFARTQWPTPQE 657
            +K Q  G           L+   L          I  +Q+  + L   F R  +P    
Sbjct: 79  SEKDQTQGHDQS-----QHLTQEYLPKEARQKQTFITWTQK--NRLVQAFERNPFPDIAT 131

Query: 658 YDQLAAKTGLVRTEIVRWFKENRCL 682
             +LA +TGL  + I  WF++ R L
Sbjct: 132 RKKLAEQTGLQESRIQMWFQKQRSL 156



 Score = 32.3 bits (72), Expect = 1.9
 Identities = 18/45 (40%), Positives = 23/45 (51%)

Query: 447 TKEQIAHLKASFLQSQFPDDAEVYRLIEVTGLARSEIKKWFSDHR 491
           T  Q   L  +F ++ FPD A   +L E TGL  S I+ WF   R
Sbjct: 110 TWTQKNRLVQAFERNPFPDIATRKKLAEQTGLQESRIQMWFQKQR 154



 Score = 30.4 bits (67), Expect = 7.1
 Identities = 16/48 (33%), Positives = 24/48 (50%)

Query: 633 IAKSQEQVHLLRSTFARTQWPTPQEYDQLAAKTGLVRTEIVRWFKENR 680
           I  +Q Q  +L+S F    +P     +QLA + G+  + I  WFK  R
Sbjct: 20  IQYNQSQKDILQSWFQHDPFPDKAAREQLAKEIGVPESNIQVWFKNYR 67


>gi|118498345 AT-binding transcription factor 1 [Homo sapiens]
          Length = 3703

 Score = 50.4 bits (119), Expect = 7e-06
 Identities = 65/290 (22%), Positives = 119/290 (41%), Gaps = 33/290 (11%)

Query: 342  PPTITVLPAQLAPTKVTQPILQTALPCQILGQTSLVLTQVTSGSTTVSCSPITLAVAGVT 401
            P +   +PA   P  +T P +  A P       S+ LTQ++        SP+ +    + 
Sbjct: 2058 PASTPAIPASAPP--ITSPTIAPAQP-------SVPLTQLSMPMELPIFSPLMMQTMPLQ 2108

Query: 402  NHGQKRPLVTPQAAP-EPKRPHIAQVPEPPPKVANPPLTPASDRKK----TKEQIAHLKA 456
                + P   PQ  P EP    +AQ+ +      NP L    +++     T +Q+  L+ 
Sbjct: 2109 TLPAQLP---PQLGPVEPLPADLAQLYQHQ---LNPTLLQQQNKRPRTRITDDQLRVLRQ 2162

Query: 457  SFLQSQFPDDAEVYRLIEVTGLARSEIKKWFSD----HRYRCQRGIVHITSESLAKDQLA 512
             F  +  P + ++  + + +GL +  IK WF +     R R +    + ++  +   +  
Sbjct: 2163 YFDINNSPSEEQIKEMADKSGLPQKVIKHWFRNTLFKERQRNKDSPYNFSNPPITSLEEL 2222

Query: 513  IAASRHGRTYHAYPDFAPQKFKEKTQG---QVKILEDSFLKSSFPTQAELDRLRVETKLS 569
               SR         ++   K   +T+    Q+++L+D F  +++P   E ++L     L 
Sbjct: 2223 KIDSRPPSPEPPKQEYWGSKRSSRTRFTDYQLRVLQDFFDANAYPKDDEFEQLSNLLNLP 2282

Query: 570  RREIDSWF-SERRKLRDSMEQAVLDSMGSGKKGQDVGAPNGALSRLDQLS 618
             R I  WF + R+K R + E     + G GK G+     N    R   L+
Sbjct: 2283 TRVIVVWFQNARQKARKNYE-----NQGEGKDGERRELTNDRYIRTSNLN 2327



 Score = 45.4 bits (106), Expect = 2e-04
 Identities = 61/289 (21%), Positives = 110/289 (38%), Gaps = 49/289 (16%)

Query: 411  TPQAAPEPKRPHIAQVPEPPPKVANPPLTPASDRKKTKEQIAHLKAS--FLQSQFPDDAE 468
            TP+  P P  P    +P  PP+ A+ P  PAS    T   IA  + S    Q   P +  
Sbjct: 2036 TPEPPPPPPPPPPPPLPAAPPQPASTPAIPASAPPITSPTIAPAQPSVPLTQLSMPMELP 2095

Query: 469  VYRLIEVTGLARSEIKKWFSDHRYRCQRGIVHITSESLAKDQLAIAASRHGRTYHAYPDF 528
            ++  + +  +    +           Q G V    E L  D   +   +   T     + 
Sbjct: 2096 IFSPLMMQTMPLQTLPAQLPP-----QLGPV----EPLPADLAQLYQHQLNPTLLQQQNK 2146

Query: 529  APQKFKEKTQGQVKILEDSFLKSSFPTQAELDRLRVETKLSRREIDSWF-----SERRKL 583
             P+     T  Q+++L   F  ++ P++ ++  +  ++ L ++ I  WF      ER++ 
Sbjct: 2147 RPRT--RITDDQLRVLRQYFDINNSPSEEQIKEMADKSGLPQKVIKHWFRNTLFKERQRN 2204

Query: 584  RDSMEQAVLDSMGSGKKGQDVGAPNGALSRLDQLSGAQLTSSLPSPSPAIAK-------- 635
            +DS                     N  ++ L++L   ++ S  PSP P   +        
Sbjct: 2205 KDS----------------PYNFSNPPITSLEEL---KIDSRPPSPEPPKQEYWGSKRSS 2245

Query: 636  ----SQEQVHLLRSTFARTQWPTPQEYDQLAAKTGLVRTEIVRWFKENR 680
                +  Q+ +L+  F    +P   E++QL+    L    IV WF+  R
Sbjct: 2246 RTRFTDYQLRVLQDFFDANAYPKDDEFEQLSNLLNLPTRVIVVWFQNAR 2294



 Score = 35.4 bits (80), Expect = 0.22
 Identities = 32/131 (24%), Positives = 49/131 (37%), Gaps = 20/131 (15%)

Query: 24   PEEVDRAKEKGIGTPQPDVAKDSWAAELENSSKENEVIEVKSMGES----------QSKK 73
            PEE+ + +E G  + Q +        EL +S   ++ I      ES          +  K
Sbjct: 1166 PEELAKDQEGGASSSQAE-------KELTDSPATSKRISFPGSSESPLSSKRPKTAEEIK 1218

Query: 74   LQGGYECKYCPYSTQNLNEFTEHVDMQHPNVILNPLYVCAECNFTTKKYDSLSDHNSKFH 133
             +  Y+C YC YS  ++N    H   QH    + P+  C  C         L  H +  H
Sbjct: 1219 PEQMYQCPYCKYSNADVNRLRVHAMTQHS---VQPMLRCPLCQDMLNNKIHLQLHLTHLH 1275

Query: 134  PGEANFKLKLI 144
                +   KLI
Sbjct: 1276 SVAPDCVEKLI 1286



 Score = 32.7 bits (73), Expect = 1.4
 Identities = 20/71 (28%), Positives = 31/71 (43%), Gaps = 11/71 (15%)

Query: 404  GQKRPLVTPQAAPE----------PKRPHIAQVPEPPPKVANPPLTPASDRKKTKEQIAH 453
            GQ +P +  Q  PE          P+   +  +P+PPP+ A PP  P      +  Q++H
Sbjct: 2448 GQPKPELQQQEQPEQKTNTPQQKLPQLVSLPSLPQPPPQ-APPPQCPLPQSSPSPSQLSH 2506

Query: 454  LKASFLQSQFP 464
            L    L +  P
Sbjct: 2507 LPLKPLHTSTP 2517



 Score = 32.7 bits (73), Expect = 1.4
 Identities = 16/45 (35%), Positives = 23/45 (51%)

Query: 537  TQGQVKILEDSFLKSSFPTQAELDRLRVETKLSRREIDSWFSERR 581
            T  Q++IL   +L  S PT+  LD +  E  L +R +  WF   R
Sbjct: 2649 TPEQLEILYQKYLLDSNPTRKMLDHIAHEVGLKKRVVQVWFQNTR 2693



 Score = 30.0 bits (66), Expect = 9.3
 Identities = 31/113 (27%), Positives = 49/113 (43%), Gaps = 18/113 (15%)

Query: 338  IQSVPPTITVLPAQLAP---------TKVTQPILQT-ALPCQILGQTSLVLTQVTSGSTT 387
            +Q +PP +  LP   +P         T +T P      LP   +    L  + + +  ++
Sbjct: 3118 LQGIPPVL--LPGLNSPSLPGFTPSNTALTSPKPNLMGLPSTTVPSPGLPTSGLPNKPSS 3175

Query: 388  VSCSPITLAVAGVTNHGQKRPLVTPQAAPEPKRPHIAQVPEPPPKVANPPLTP 440
             S S  T A A +   G ++P   PQ   + ++P + Q   PPP  A PP TP
Sbjct: 3176 ASLSSPTPAQATMAM-GPQQP---PQQQQQQQQPQVQQ--PPPPPAAQPPPTP 3222


>gi|126090663 zinc finger homeodomain 4 [Homo sapiens]
          Length = 3571

 Score = 45.8 bits (107), Expect = 2e-04
 Identities = 57/260 (21%), Positives = 107/260 (41%), Gaps = 46/260 (17%)

Query: 340  SVPPTITV---LPAQLAPTKVTQPILQTALPCQILGQTSLVLTQVTSGSTTVSCSPITLA 396
            S PP + +   L   L P+ + QP+   ALP Q+    +L L Q+ + S  ++       
Sbjct: 2017 SAPPQVQLPVSLDLPLFPSIMMQPVQHPALPPQL----ALQLPQMDALSADLT------- 2065

Query: 397  VAGVTNHGQKRPLVTPQAAPEPKRPHIAQVPEPPPKVANPPLTPASDRKKTKEQIAHLKA 456
                        L   Q   +P     +Q   P  ++             T +Q+  L+A
Sbjct: 2066 -----------QLCQQQLGLDPNFLRHSQFKRPRTRI-------------TDDQLKILRA 2101

Query: 457  SFLQSQFPDDAEVYRLIEVTGLARSEIKKWFSD----HRYRCQRGIVHITSESLA--KDQ 510
             F  +  P + ++  + E +GL++  IK WF +     R R +    + ++  +   +D 
Sbjct: 2102 YFDINNSPSEEQIQEMAEKSGLSQKVIKHWFRNTLFKERQRNKDSPYNFSNPPITVLEDI 2161

Query: 511  LAIAASRHGRTYHAYPDFAPQKFKEK-TQGQVKILEDSFLKSSFPTQAELDRLRVETKLS 569
                       Y +   F+ +  + + T  Q+++L+D F  +++P   E+++L     L 
Sbjct: 2162 RIDPQPTSLEHYKSDASFSKRSSRTRFTDYQLRVLQDFFDTNAYPKDDEIEQLSTVLNLP 2221

Query: 570  RREIDSWF-SERRKLRDSME 588
             R I  WF + R+K R S E
Sbjct: 2222 TRVIVVWFQNARQKARKSYE 2241



 Score = 38.5 bits (88), Expect = 0.026
 Identities = 47/231 (20%), Positives = 88/231 (38%), Gaps = 26/231 (11%)

Query: 13   VRTSQVVEQDVPEEVDRAKEKGIGTPQPDVAKDSWAAELENSSKENEVIEVKSMGESQSK 72
            ++ + V E D  +  +R   +G  + +  V+       L  + +E+   +     E    
Sbjct: 1107 IKPTAVAEDDEKDTSERDNSEGKNSNKDSVSVAGGTQPLLLAKEEDVATKRSKPTEDNKF 1166

Query: 73   KLQGGYECKYCPYSTQNLNEFTEHVDMQHPNVILNPLYVCAECNFTTKKYDSLSDHNSKF 132
              +  Y+C YC Y++++ +    HV  QH    + P+  C  C         L  H +  
Sbjct: 1167 CHEQFYQCPYCNYNSRDQSRIQMHVLSQHS---VQPVICCPLCQDVLSNKMHLQLHLTHL 1223

Query: 133  HPGEANFKLKL--------IKRNNQTVL-----EQSIETTNHVVSITTSGPGTGDSD--- 176
            H    +   KL        +   N  +L     E+S   T   V+   SG  +G+S    
Sbjct: 1224 HSVSPDCVEKLLMTVPVPDVMMPNSMLLPAAASEKSERDTPAAVTAEGSGKYSGESPMDD 1283

Query: 177  ---SGISVSKTPIMKPGKPKADAKKVPKKPEEITPENHVEGTARLVTDTAE 224
               +G+  SK  +    + K + +K  K+P E++  N        + DT +
Sbjct: 1284 KSMAGLEDSKANV----EVKNEEQKPTKEPLEVSEWNKNSSKDVKIPDTLQ 1330



 Score = 33.9 bits (76), Expect = 0.64
 Identities = 31/105 (29%), Positives = 44/105 (41%), Gaps = 8/105 (7%)

Query: 537  TQGQVKILEDSFLKSSFPTQAELDRLRVETKLSRREIDSWFSERRKLRDSMEQAVLDSMG 596
            T  Q++IL + +L  S PT+  LD +  E  L +R +  WF   R      +   +    
Sbjct: 2568 TPEQLEILYEKYLLDSNPTRKMLDHIAREVGLKKRVVQVWFQNTRARERKGQFRAVGPAQ 2627

Query: 597  SGKKGQDVGAPNGALSRLDQ-------LSGAQLTSSLPSPSPAIA 634
            S K+     A   A S L+          G Q   SLP PSP I+
Sbjct: 2628 SHKRCPFCRALFKAKSALESHIRSRHWNEGKQAGYSLP-PSPLIS 2671



 Score = 30.4 bits (67), Expect = 7.1
 Identities = 13/47 (27%), Positives = 26/47 (55%)

Query: 631  PAIAKSQEQVHLLRSTFARTQWPTPQEYDQLAAKTGLVRTEIVRWFK 677
            P    + +Q+ +LR+ F     P+ ++  ++A K+GL +  I  WF+
Sbjct: 2087 PRTRITDDQLKILRAYFDINNSPSEEQIQEMAEKSGLSQKVIKHWFR 2133


>gi|23943886 Rhox homeobox family, member 1 [Homo sapiens]
          Length = 184

 Score = 45.8 bits (107), Expect = 2e-04
 Identities = 29/94 (30%), Positives = 46/94 (48%), Gaps = 7/94 (7%)

Query: 404 GQKRPLVTPQAAPEPKRPHIAQVPEPPPKVANPPLTPASDRKK-TKEQIAHLKASFLQSQ 462
           G + P   PQ  P P+ P  A +  P P+     + P + R K T  Q+  L++ F  +Q
Sbjct: 73  GNQEPRQQPQ--PPPEEPAQAAMEGPQPE----NMQPRTRRTKFTLLQVEELESVFRHTQ 126

Query: 463 FPDDAEVYRLIEVTGLARSEIKKWFSDHRYRCQR 496
           +PD      L E  G+   +++ WF + R RC+R
Sbjct: 127 YPDVPTRRELAENLGVTEDKVRVWFKNKRARCRR 160



 Score = 30.8 bits (68), Expect = 5.4
 Identities = 15/42 (35%), Positives = 20/42 (47%)

Query: 639 QVHLLRSTFARTQWPTPQEYDQLAAKTGLVRTEIVRWFKENR 680
           QV  L S F  TQ+P      +LA   G+   ++  WFK  R
Sbjct: 114 QVEELESVFRHTQYPDVPTRRELAENLGVTEDKVRVWFKNKR 155


>gi|189181724 proteoglycan 4 isoform D [Homo sapiens]
          Length = 1270

 Score = 45.1 bits (105), Expect = 3e-04
 Identities = 74/311 (23%), Positives = 110/311 (35%), Gaps = 51/311 (16%)

Query: 150 TVLEQSIETT------NHVVSITTSGPGTGDSDSGISVSKTPIMKPGKPKADAKKVPKKP 203
           T L++   TT        +   TT GP +  SD     +      P  PK  A   PKKP
Sbjct: 650 TTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETA-PTTPKEPAPTTPKKP 708

Query: 204 EEITPENHVEGTARLVTDTAEILSRLGGVELLQDTLGHVMPSVQLPPNINLVPKVPVPLN 263
              TPE     T+ + T T             + T  H  P  +  P ++  P  P  L 
Sbjct: 709 APTTPETPPPTTSEVSTPTT----------TKEPTTIHKSPD-ESTPELSAEP-TPKALE 756

Query: 264 TTKYNSALDTNATMINSFNKFPYPTQAELSWLTAASKHPEEHIRIWFATQRLKHGISWSP 323
            +     + T  T        P  T+ E++  TA  K  E  +R              + 
Sbjct: 757 NSPKEPGVPTTKT--------PAATKPEMT-TTAKDKTTERDLR--------------TT 793

Query: 324 EEVEEARKKMFNGTIQSVPPTITVLPAQLAPTKVTQPILQTALPCQILG-QTSLVLTQVT 382
            E   A  KM   T  +   T T        T+VT    Q   P +I   +T+ +  +VT
Sbjct: 794 PETTTAAPKMTKETATTTEKT-TESKITATTTQVTSTTTQDTTPFKITTLKTTTLAPKVT 852

Query: 383 SGSTTVSCSPI---TLAVAGVTNHGQKRPLVTP---QAAPEPKRPHIAQVPEPPPKVANP 436
           +   T++ + I       A   +        TP   +    PK+P   + P+  P+V  P
Sbjct: 853 TTKKTITTTEIMNKPEETAKPKDRATNSKATTPKPQKPTKAPKKPTSTKKPKTMPRVRKP 912

Query: 437 PLTPASDRKKT 447
             TP + RK T
Sbjct: 913 KTTP-TPRKMT 922



 Score = 34.7 bits (78), Expect = 0.38
 Identities = 64/269 (23%), Positives = 88/269 (32%), Gaps = 13/269 (4%)

Query: 189 PGKPKADAKKVPKKPEEITPENHVEGTARLVTDTAEILSRLGGVELLQDTLGHVMPSVQL 248
           P  PK  A   PKKP   TP+     T +  T T          E    T     P+   
Sbjct: 295 PTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPK 354

Query: 249 PPNINLVPKVPVPLNTTKYNSALDTNATMINSFNKFPYPTQAELSWLTAASKHPEEHIRI 308
            P     PK P P  TT    A  T      +  K P PT  + +  T  +K P      
Sbjct: 355 KP-APTTPKEPAP--TTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTT--TKEPAPTTTK 409

Query: 309 WFATQRLKHGISWSPEEVEEARKKMFNGTIQSVPPTITVLPAQLAPTKVTQPI-LQTALP 367
              T   +   + + E      K+    T +   PT    P + APT   +P    T  P
Sbjct: 410 SAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPT---TPKEPAPTTPKEPAPTTTKKP 466

Query: 368 CQILGQTSLVLT-QVTSGSTTVSCSPITLAVAGVTNHGQKRPLVTPQAA---PEPKRPHI 423
                +     T + T+ +T    +P T      T   +  P    + A   PE   P  
Sbjct: 467 APTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTT 526

Query: 424 AQVPEPPPKVANPPLTPASDRKKTKEQIA 452
            + P P    A  P TP      T ++ A
Sbjct: 527 PEEPAPTTPKAAAPNTPKEPAPTTPKEPA 555



 Score = 30.4 bits (67), Expect = 7.1
 Identities = 69/311 (22%), Positives = 99/311 (31%), Gaps = 30/311 (9%)

Query: 150 TVLEQSIETTNHVVSITTSGPGTGDSDSGISVSKTPIMKPGKPKADAKKVPKKPEEITPE 209
           T  E+   TT   ++ TT    T  +    + +      P  PK  A   PK+P   TP+
Sbjct: 501 TTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPK 560

Query: 210 NHVEGTARLVTDTAEILSRLGGVELLQDTLGHVMPSV-QLPPNINLVP-KVPVPLNTTKY 267
                T +    T               TL    P+  + P    L P     P +TT  
Sbjct: 561 EPAPTTPKETAPTTP-------KGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCD 613

Query: 268 NSALDTNATMINSFNKFPYPTQAELSWLTAASKHPEEHIRIWFATQRLKHGISWSPEEVE 327
             A  T      +  K P PT           K P        A   LK     +P+  +
Sbjct: 614 KPAPTTPKGTAPTTPKEPAPT---------TPKEPAPTTPKGTAPTTLKEPAPTTPK--K 662

Query: 328 EARKKMFNGTIQSVPPTITVLPAQLAPTKVTQPILQTALPCQILGQTSLVLTQVTSGSTT 387
            A K++   T +    T +  PA   P K T P      P     +     T  T   TT
Sbjct: 663 PAPKELAPTTTKGPTSTTSDKPAPTTP-KETAPTTPKE-PAPTTPKKPAPTTPETPPPTT 720

Query: 388 VSCSPITLAVAGVTNHGQKRPLVTPQAAPEPKRPHIAQVPEPP-------PKVANPPLTP 440
              S  T      T H +     TP+ + EP    +   P+ P       P    P +T 
Sbjct: 721 SEVSTPTTTKEPTTIH-KSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTT 779

Query: 441 ASDRKKTKEQI 451
            +  K T+  +
Sbjct: 780 TAKDKTTERDL 790


>gi|189181722 proteoglycan 4 isoform C [Homo sapiens]
          Length = 1311

 Score = 45.1 bits (105), Expect = 3e-04
 Identities = 74/311 (23%), Positives = 110/311 (35%), Gaps = 51/311 (16%)

Query: 150 TVLEQSIETT------NHVVSITTSGPGTGDSDSGISVSKTPIMKPGKPKADAKKVPKKP 203
           T L++   TT        +   TT GP +  SD     +      P  PK  A   PKKP
Sbjct: 691 TTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETA-PTTPKEPAPTTPKKP 749

Query: 204 EEITPENHVEGTARLVTDTAEILSRLGGVELLQDTLGHVMPSVQLPPNINLVPKVPVPLN 263
              TPE     T+ + T T             + T  H  P  +  P ++  P  P  L 
Sbjct: 750 APTTPETPPPTTSEVSTPTT----------TKEPTTIHKSPD-ESTPELSAEP-TPKALE 797

Query: 264 TTKYNSALDTNATMINSFNKFPYPTQAELSWLTAASKHPEEHIRIWFATQRLKHGISWSP 323
            +     + T  T        P  T+ E++  TA  K  E  +R              + 
Sbjct: 798 NSPKEPGVPTTKT--------PAATKPEMT-TTAKDKTTERDLR--------------TT 834

Query: 324 EEVEEARKKMFNGTIQSVPPTITVLPAQLAPTKVTQPILQTALPCQILG-QTSLVLTQVT 382
            E   A  KM   T  +   T T        T+VT    Q   P +I   +T+ +  +VT
Sbjct: 835 PETTTAAPKMTKETATTTEKT-TESKITATTTQVTSTTTQDTTPFKITTLKTTTLAPKVT 893

Query: 383 SGSTTVSCSPI---TLAVAGVTNHGQKRPLVTP---QAAPEPKRPHIAQVPEPPPKVANP 436
           +   T++ + I       A   +        TP   +    PK+P   + P+  P+V  P
Sbjct: 894 TTKKTITTTEIMNKPEETAKPKDRATNSKATTPKPQKPTKAPKKPTSTKKPKTMPRVRKP 953

Query: 437 PLTPASDRKKT 447
             TP + RK T
Sbjct: 954 KTTP-TPRKMT 963



 Score = 34.7 bits (78), Expect = 0.38
 Identities = 64/269 (23%), Positives = 88/269 (32%), Gaps = 13/269 (4%)

Query: 189 PGKPKADAKKVPKKPEEITPENHVEGTARLVTDTAEILSRLGGVELLQDTLGHVMPSVQL 248
           P  PK  A   PKKP   TP+     T +  T T          E    T     P+   
Sbjct: 336 PTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPK 395

Query: 249 PPNINLVPKVPVPLNTTKYNSALDTNATMINSFNKFPYPTQAELSWLTAASKHPEEHIRI 308
            P     PK P P  TT    A  T      +  K P PT  + +  T  +K P      
Sbjct: 396 KP-APTTPKEPAP--TTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTT--TKEPAPTTTK 450

Query: 309 WFATQRLKHGISWSPEEVEEARKKMFNGTIQSVPPTITVLPAQLAPTKVTQPI-LQTALP 367
              T   +   + + E      K+    T +   PT    P + APT   +P    T  P
Sbjct: 451 SAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPT---TPKEPAPTTPKEPAPTTTKKP 507

Query: 368 CQILGQTSLVLT-QVTSGSTTVSCSPITLAVAGVTNHGQKRPLVTPQAA---PEPKRPHI 423
                +     T + T+ +T    +P T      T   +  P    + A   PE   P  
Sbjct: 508 APTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTT 567

Query: 424 AQVPEPPPKVANPPLTPASDRKKTKEQIA 452
            + P P    A  P TP      T ++ A
Sbjct: 568 PEEPAPTTPKAAAPNTPKEPAPTTPKEPA 596



 Score = 30.4 bits (67), Expect = 7.1
 Identities = 69/311 (22%), Positives = 99/311 (31%), Gaps = 30/311 (9%)

Query: 150 TVLEQSIETTNHVVSITTSGPGTGDSDSGISVSKTPIMKPGKPKADAKKVPKKPEEITPE 209
           T  E+   TT   ++ TT    T  +    + +      P  PK  A   PK+P   TP+
Sbjct: 542 TTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPK 601

Query: 210 NHVEGTARLVTDTAEILSRLGGVELLQDTLGHVMPSV-QLPPNINLVP-KVPVPLNTTKY 267
                T +    T               TL    P+  + P    L P     P +TT  
Sbjct: 602 EPAPTTPKETAPTTP-------KGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCD 654

Query: 268 NSALDTNATMINSFNKFPYPTQAELSWLTAASKHPEEHIRIWFATQRLKHGISWSPEEVE 327
             A  T      +  K P PT           K P        A   LK     +P+  +
Sbjct: 655 KPAPTTPKGTAPTTPKEPAPT---------TPKEPAPTTPKGTAPTTLKEPAPTTPK--K 703

Query: 328 EARKKMFNGTIQSVPPTITVLPAQLAPTKVTQPILQTALPCQILGQTSLVLTQVTSGSTT 387
            A K++   T +    T +  PA   P K T P      P     +     T  T   TT
Sbjct: 704 PAPKELAPTTTKGPTSTTSDKPAPTTP-KETAPTTPKE-PAPTTPKKPAPTTPETPPPTT 761

Query: 388 VSCSPITLAVAGVTNHGQKRPLVTPQAAPEPKRPHIAQVPEPP-------PKVANPPLTP 440
              S  T      T H +     TP+ + EP    +   P+ P       P    P +T 
Sbjct: 762 SEVSTPTTTKEPTTIH-KSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTT 820

Query: 441 ASDRKKTKEQI 451
            +  K T+  +
Sbjct: 821 TAKDKTTERDL 831


>gi|189181720 proteoglycan 4 isoform B [Homo sapiens]
          Length = 1363

 Score = 45.1 bits (105), Expect = 3e-04
 Identities = 74/311 (23%), Positives = 110/311 (35%), Gaps = 51/311 (16%)

Query: 150  TVLEQSIETT------NHVVSITTSGPGTGDSDSGISVSKTPIMKPGKPKADAKKVPKKP 203
            T L++   TT        +   TT GP +  SD     +      P  PK  A   PKKP
Sbjct: 743  TTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETA-PTTPKEPAPTTPKKP 801

Query: 204  EEITPENHVEGTARLVTDTAEILSRLGGVELLQDTLGHVMPSVQLPPNINLVPKVPVPLN 263
               TPE     T+ + T T             + T  H  P  +  P ++  P  P  L 
Sbjct: 802  APTTPETPPPTTSEVSTPTT----------TKEPTTIHKSPD-ESTPELSAEP-TPKALE 849

Query: 264  TTKYNSALDTNATMINSFNKFPYPTQAELSWLTAASKHPEEHIRIWFATQRLKHGISWSP 323
             +     + T  T        P  T+ E++  TA  K  E  +R              + 
Sbjct: 850  NSPKEPGVPTTKT--------PAATKPEMT-TTAKDKTTERDLR--------------TT 886

Query: 324  EEVEEARKKMFNGTIQSVPPTITVLPAQLAPTKVTQPILQTALPCQILG-QTSLVLTQVT 382
             E   A  KM   T  +   T T        T+VT    Q   P +I   +T+ +  +VT
Sbjct: 887  PETTTAAPKMTKETATTTEKT-TESKITATTTQVTSTTTQDTTPFKITTLKTTTLAPKVT 945

Query: 383  SGSTTVSCSPI---TLAVAGVTNHGQKRPLVTP---QAAPEPKRPHIAQVPEPPPKVANP 436
            +   T++ + I       A   +        TP   +    PK+P   + P+  P+V  P
Sbjct: 946  TTKKTITTTEIMNKPEETAKPKDRATNSKATTPKPQKPTKAPKKPTSTKKPKTMPRVRKP 1005

Query: 437  PLTPASDRKKT 447
              TP + RK T
Sbjct: 1006 KTTP-TPRKMT 1015



 Score = 34.7 bits (78), Expect = 0.38
 Identities = 64/269 (23%), Positives = 88/269 (32%), Gaps = 13/269 (4%)

Query: 189 PGKPKADAKKVPKKPEEITPENHVEGTARLVTDTAEILSRLGGVELLQDTLGHVMPSVQL 248
           P  PK  A   PKKP   TP+     T +  T T          E    T     P+   
Sbjct: 388 PTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPK 447

Query: 249 PPNINLVPKVPVPLNTTKYNSALDTNATMINSFNKFPYPTQAELSWLTAASKHPEEHIRI 308
            P     PK P P  TT    A  T      +  K P PT  + +  T  +K P      
Sbjct: 448 KP-APTTPKEPAP--TTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTT--TKEPAPTTTK 502

Query: 309 WFATQRLKHGISWSPEEVEEARKKMFNGTIQSVPPTITVLPAQLAPTKVTQPI-LQTALP 367
              T   +   + + E      K+    T +   PT    P + APT   +P    T  P
Sbjct: 503 SAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPT---TPKEPAPTTPKEPAPTTTKKP 559

Query: 368 CQILGQTSLVLT-QVTSGSTTVSCSPITLAVAGVTNHGQKRPLVTPQAA---PEPKRPHI 423
                +     T + T+ +T    +P T      T   +  P    + A   PE   P  
Sbjct: 560 APTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTT 619

Query: 424 AQVPEPPPKVANPPLTPASDRKKTKEQIA 452
            + P P    A  P TP      T ++ A
Sbjct: 620 PEEPAPTTPKAAAPNTPKEPAPTTPKEPA 648



 Score = 30.4 bits (67), Expect = 7.1
 Identities = 69/311 (22%), Positives = 99/311 (31%), Gaps = 30/311 (9%)

Query: 150 TVLEQSIETTNHVVSITTSGPGTGDSDSGISVSKTPIMKPGKPKADAKKVPKKPEEITPE 209
           T  E+   TT   ++ TT    T  +    + +      P  PK  A   PK+P   TP+
Sbjct: 594 TTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPK 653

Query: 210 NHVEGTARLVTDTAEILSRLGGVELLQDTLGHVMPSV-QLPPNINLVP-KVPVPLNTTKY 267
                T +    T               TL    P+  + P    L P     P +TT  
Sbjct: 654 EPAPTTPKETAPTTP-------KGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCD 706

Query: 268 NSALDTNATMINSFNKFPYPTQAELSWLTAASKHPEEHIRIWFATQRLKHGISWSPEEVE 327
             A  T      +  K P PT           K P        A   LK     +P+  +
Sbjct: 707 KPAPTTPKGTAPTTPKEPAPT---------TPKEPAPTTPKGTAPTTLKEPAPTTPK--K 755

Query: 328 EARKKMFNGTIQSVPPTITVLPAQLAPTKVTQPILQTALPCQILGQTSLVLTQVTSGSTT 387
            A K++   T +    T +  PA   P K T P      P     +     T  T   TT
Sbjct: 756 PAPKELAPTTTKGPTSTTSDKPAPTTP-KETAPTTPKE-PAPTTPKKPAPTTPETPPPTT 813

Query: 388 VSCSPITLAVAGVTNHGQKRPLVTPQAAPEPKRPHIAQVPEPP-------PKVANPPLTP 440
              S  T      T H +     TP+ + EP    +   P+ P       P    P +T 
Sbjct: 814 SEVSTPTTTKEPTTIH-KSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTT 872

Query: 441 ASDRKKTKEQI 451
            +  K T+  +
Sbjct: 873 TAKDKTTERDL 883


>gi|67190163 proteoglycan 4 isoform A [Homo sapiens]
          Length = 1404

 Score = 45.1 bits (105), Expect = 3e-04
 Identities = 74/311 (23%), Positives = 110/311 (35%), Gaps = 51/311 (16%)

Query: 150  TVLEQSIETT------NHVVSITTSGPGTGDSDSGISVSKTPIMKPGKPKADAKKVPKKP 203
            T L++   TT        +   TT GP +  SD     +      P  PK  A   PKKP
Sbjct: 784  TTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETA-PTTPKEPAPTTPKKP 842

Query: 204  EEITPENHVEGTARLVTDTAEILSRLGGVELLQDTLGHVMPSVQLPPNINLVPKVPVPLN 263
               TPE     T+ + T T             + T  H  P  +  P ++  P  P  L 
Sbjct: 843  APTTPETPPPTTSEVSTPTT----------TKEPTTIHKSPD-ESTPELSAEP-TPKALE 890

Query: 264  TTKYNSALDTNATMINSFNKFPYPTQAELSWLTAASKHPEEHIRIWFATQRLKHGISWSP 323
             +     + T  T        P  T+ E++  TA  K  E  +R              + 
Sbjct: 891  NSPKEPGVPTTKT--------PAATKPEMT-TTAKDKTTERDLR--------------TT 927

Query: 324  EEVEEARKKMFNGTIQSVPPTITVLPAQLAPTKVTQPILQTALPCQILG-QTSLVLTQVT 382
             E   A  KM   T  +   T T        T+VT    Q   P +I   +T+ +  +VT
Sbjct: 928  PETTTAAPKMTKETATTTEKT-TESKITATTTQVTSTTTQDTTPFKITTLKTTTLAPKVT 986

Query: 383  SGSTTVSCSPI---TLAVAGVTNHGQKRPLVTP---QAAPEPKRPHIAQVPEPPPKVANP 436
            +   T++ + I       A   +        TP   +    PK+P   + P+  P+V  P
Sbjct: 987  TTKKTITTTEIMNKPEETAKPKDRATNSKATTPKPQKPTKAPKKPTSTKKPKTMPRVRKP 1046

Query: 437  PLTPASDRKKT 447
              TP + RK T
Sbjct: 1047 KTTP-TPRKMT 1056



 Score = 34.7 bits (78), Expect = 0.38
 Identities = 64/269 (23%), Positives = 88/269 (32%), Gaps = 13/269 (4%)

Query: 189 PGKPKADAKKVPKKPEEITPENHVEGTARLVTDTAEILSRLGGVELLQDTLGHVMPSVQL 248
           P  PK  A   PKKP   TP+     T +  T T          E    T     P+   
Sbjct: 429 PTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPK 488

Query: 249 PPNINLVPKVPVPLNTTKYNSALDTNATMINSFNKFPYPTQAELSWLTAASKHPEEHIRI 308
            P     PK P P  TT    A  T      +  K P PT  + +  T  +K P      
Sbjct: 489 KP-APTTPKEPAP--TTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTT--TKEPAPTTTK 543

Query: 309 WFATQRLKHGISWSPEEVEEARKKMFNGTIQSVPPTITVLPAQLAPTKVTQPI-LQTALP 367
              T   +   + + E      K+    T +   PT    P + APT   +P    T  P
Sbjct: 544 SAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPT---TPKEPAPTTPKEPAPTTTKKP 600

Query: 368 CQILGQTSLVLT-QVTSGSTTVSCSPITLAVAGVTNHGQKRPLVTPQAA---PEPKRPHI 423
                +     T + T+ +T    +P T      T   +  P    + A   PE   P  
Sbjct: 601 APTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTT 660

Query: 424 AQVPEPPPKVANPPLTPASDRKKTKEQIA 452
            + P P    A  P TP      T ++ A
Sbjct: 661 PEEPAPTTPKAAAPNTPKEPAPTTPKEPA 689



 Score = 30.4 bits (67), Expect = 7.1
 Identities = 69/311 (22%), Positives = 99/311 (31%), Gaps = 30/311 (9%)

Query: 150 TVLEQSIETTNHVVSITTSGPGTGDSDSGISVSKTPIMKPGKPKADAKKVPKKPEEITPE 209
           T  E+   TT   ++ TT    T  +    + +      P  PK  A   PK+P   TP+
Sbjct: 635 TTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPK 694

Query: 210 NHVEGTARLVTDTAEILSRLGGVELLQDTLGHVMPSV-QLPPNINLVP-KVPVPLNTTKY 267
                T +    T               TL    P+  + P    L P     P +TT  
Sbjct: 695 EPAPTTPKETAPTTP-------KGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCD 747

Query: 268 NSALDTNATMINSFNKFPYPTQAELSWLTAASKHPEEHIRIWFATQRLKHGISWSPEEVE 327
             A  T      +  K P PT           K P        A   LK     +P+  +
Sbjct: 748 KPAPTTPKGTAPTTPKEPAPT---------TPKEPAPTTPKGTAPTTLKEPAPTTPK--K 796

Query: 328 EARKKMFNGTIQSVPPTITVLPAQLAPTKVTQPILQTALPCQILGQTSLVLTQVTSGSTT 387
            A K++   T +    T +  PA   P K T P      P     +     T  T   TT
Sbjct: 797 PAPKELAPTTTKGPTSTTSDKPAPTTP-KETAPTTPKE-PAPTTPKKPAPTTPETPPPTT 854

Query: 388 VSCSPITLAVAGVTNHGQKRPLVTPQAAPEPKRPHIAQVPEPP-------PKVANPPLTP 440
              S  T      T H +     TP+ + EP    +   P+ P       P    P +T 
Sbjct: 855 SEVSTPTTTKEPTTIH-KSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTT 913

Query: 441 ASDRKKTKEQI 451
            +  K T+  +
Sbjct: 914 TAKDKTTERDL 924


>gi|21956641 ISL LIM homeobox 2 [Homo sapiens]
          Length = 359

 Score = 44.7 bits (104), Expect = 4e-04
 Identities = 32/108 (29%), Positives = 47/108 (43%), Gaps = 3/108 (2%)

Query: 636 SQEQVHLLRSTFARTQWPTPQEYDQLAAKTGLVRTEIVRWFKENRCLLKTGTV--KWMEQ 693
           +++Q+H LR+ +A    P     +QL   TGL    I  WF+  RC  K  ++  K ++Q
Sbjct: 199 NEKQLHTLRTCYAANPRPDALMKEQLVEMTGLSPRVIRVWFQNKRCKDKKKSILMKQLQQ 258

Query: 694 YQHQPMADDHGYDAVARKATKPMA-ESPKNGGDVVPQYYKDPKKLCEE 740
            QH       G       A  P+  E+   G  V  Q Y+ P K   E
Sbjct: 259 QQHSDKTSLQGLTGTPLVAGSPIRHENAVQGSAVEVQTYQPPWKALSE 306



 Score = 34.3 bits (77), Expect = 0.49
 Identities = 37/160 (23%), Positives = 68/160 (42%), Gaps = 15/160 (9%)

Query: 420 RPHIAQVPEPPPKVANPPLTPASDRKKTKEQIAHLKASFLQSQFPDDAEVYRLIEVTGLA 479
           RPH+ +  E   +V              ++Q+  L+  +  +  PD     +L+E+TGL+
Sbjct: 181 RPHVHKQTEKTTRVRTV---------LNEKQLHTLRTCYAANPRPDALMKEQLVEMTGLS 231

Query: 480 RSEIKKWFSDHRYRCQRGIVHITSESLAKDQLAIAASRHGRTYHAYPDFAPQKFKEKTQG 539
              I+ WF +   RC+     I  + L + Q +   S  G T       +P + +   QG
Sbjct: 232 PRVIRVWFQNK--RCKDKKKSILMKQLQQQQHSDKTSLQGLTGTPLVAGSPIRHENAVQG 289

Query: 540 ---QVKILEDSF-LKSSFPTQAELDRLRVETKLSRREIDS 575
              +V+  +  +   S F  Q++LD+   +  +S  E  S
Sbjct: 290 SAVEVQTYQPPWKALSEFALQSDLDQPAFQQLVSFSESGS 329


>gi|138175817 zinc finger protein 236 [Homo sapiens]
          Length = 1845

 Score = 44.3 bits (103), Expect = 5e-04
 Identities = 20/58 (34%), Positives = 25/58 (43%)

Query: 78  YECKYCPYSTQNLNEFTEHVDMQHPNVILNPLYVCAECNFTTKKYDSLSDHNSKFHPG 135
           + C +CP +         HV   H  V   P Y C EC+   K   SL+ H SK H G
Sbjct: 253 HACAFCPAAFSQKGNLQSHVQRVHSEVKNGPTYNCTECSCVFKSLGSLNTHISKMHMG 310


>gi|61969662 double homeobox A [Homo sapiens]
          Length = 204

 Score = 43.9 bits (102), Expect = 6e-04
 Identities = 34/148 (22%), Positives = 61/148 (41%), Gaps = 15/148 (10%)

Query: 537 TQGQVKILEDSFLKSSFPTQAELDRLRVETKLSRREIDSWFSERRKLRDSMEQAVLDSMG 596
           T+ Q+KIL ++F +  +P  A   +L +E       I  WF  RR      ++   +++ 
Sbjct: 23  TEEQLKILINTFNQKPYPGYATKQKLALEINTEESRIQIWFQNRRARHGFQKRPEAETLE 82

Query: 597 SGK-KGQDVGAPNGALSRLDQLSGAQLTSSLPSPSPAIAKSQEQVHLLRSTFARTQWPTP 655
           S + +GQD               G +   S  +       S  Q+H L   F +  +P  
Sbjct: 83  SSQSQGQD-------------QPGVEF-QSREARRCRTTYSASQLHTLIKAFMKNPYPGI 128

Query: 656 QEYDQLAAKTGLVRTEIVRWFKENRCLL 683
              ++LA + G+  + +  WF+  R  L
Sbjct: 129 DSREELAKEIGVPESRVQIWFQNRRSRL 156



 Score = 41.2 bits (95), Expect = 0.004
 Identities = 19/48 (39%), Positives = 25/48 (52%)

Query: 277 MINSFNKFPYPTQAELSWLTAASKHPEEHIRIWFATQRLKHGISWSPE 324
           +IN+FN+ PYP  A    L       E  I+IWF  +R +HG    PE
Sbjct: 30  LINTFNQKPYPGYATKQKLALEINTEESRIQIWFQNRRARHGFQKRPE 77



 Score = 36.2 bits (82), Expect = 0.13
 Identities = 45/191 (23%), Positives = 73/191 (38%), Gaps = 28/191 (14%)

Query: 445 KKTKEQIAHLKASFLQSQFPDDAEVYRLIEVTGLARSEIKKWFSDHRYR-----CQRGIV 499
           K T+EQ+  L  +F Q  +P  A   +L        S I+ WF + R R           
Sbjct: 21  KFTEEQLKILINTFNQKPYPGYATKQKLALEINTEESRIQIWFQNRRARHGFQKRPEAET 80

Query: 500 HITSESLAKDQLAI-----AASRHGRTYHAYPDFAPQKFKEKTQGQVKILEDSFLKSSFP 554
             +S+S  +DQ  +      A R   TY A               Q+  L  +F+K+ +P
Sbjct: 81  LESSQSQGQDQPGVEFQSREARRCRTTYSA--------------SQLHTLIKAFMKNPYP 126

Query: 555 TQAELDRLRVETKLSRREIDSWFSERR-KLRDSMEQAVLDSMGSGKKGQDVGAPNGALSR 613
                + L  E  +    +  WF  RR +L    ++  + S+   ++G+    P G    
Sbjct: 127 GIDSREELAKEIGVPESRVQIWFQNRRSRLLLQRKREPVASLEQEEQGK---IPEGLQGA 183

Query: 614 LDQLSGAQLTS 624
            D  +G   TS
Sbjct: 184 EDTQNGTNFTS 194


>gi|4557489 cone-rod homeobox protein [Homo sapiens]
          Length = 299

 Score = 43.5 bits (101), Expect = 8e-04
 Identities = 28/93 (30%), Positives = 44/93 (47%), Gaps = 6/93 (6%)

Query: 636 SQEQVHLLRSTFARTQWPTPQEYDQLAAKTGLVRTEIVRWFKENRCLLKTGTVKWMEQYQ 695
           ++ Q+  L + FA+TQ+P     +++A K  L  + +  WFK  R   K    +  ++ Q
Sbjct: 47  TRSQLEELEALFAKTQYPDVYAREEVALKINLPESRVQVWFKNRRA--KCRQQRQQQKQQ 104

Query: 696 HQPMADDHGYDAVARKATKPMAESPKNGGDVVP 728
            QP     G  A AR A +    SP+   DV P
Sbjct: 105 QQP----PGGQAKARPAKRKAGTSPRPSTDVCP 133



 Score = 35.8 bits (81), Expect = 0.17
 Identities = 21/67 (31%), Positives = 35/67 (52%), Gaps = 10/67 (14%)

Query: 437 PLTPASDRKK----TKEQIAHLKASFLQSQFPDDAEVYRLIEVT---GLARSEIKKWFSD 489
           P  P   R++    T+ Q+  L+A F ++Q+PD   VY   EV     L  S ++ WF +
Sbjct: 33  PSAPRKQRRERTTFTRSQLEELEALFAKTQYPD---VYAREEVALKINLPESRVQVWFKN 89

Query: 490 HRYRCQR 496
            R +C++
Sbjct: 90  RRAKCRQ 96


>gi|21361183 paired-like homeodomain transcription factor 2 isoform
           c [Homo sapiens]
          Length = 324

 Score = 43.1 bits (100), Expect = 0.001
 Identities = 58/269 (21%), Positives = 115/269 (42%), Gaps = 34/269 (12%)

Query: 379 TQVTSGSTTVSCSPITLAVAGVTNHGQKRPL-----------VTPQAAPEPKRPHIAQVP 427
           T++++ S++    P  LA+A V   GQ R L           ++  ++PE      +Q  
Sbjct: 17  TKLSAVSSSSCHHPQPLAMASVLAPGQPRSLDSSKHRLEVHTISDTSSPEAAEKDKSQQG 76

Query: 428 EPPPKVANPPLTPASDRKK----TKEQIAHLKASFLQSQFPDDAEVYRLIEVTGLARSEI 483
           +     A  P      R++    T +Q+  L+A+F ++++PD +    +   T L  + +
Sbjct: 77  KNEDVGAEDPSKKKRQRRQRTHFTSQQLQELEATFQRNRYPDMSTREEIAVWTNLTEARV 136

Query: 484 KKWFSDHRYRCQRGIVHITSESLAKDQLAIAASRHGRTY-HAYPDFAPQKFKEKTQGQVK 542
           + WF + R + ++   +  +E L K+      +   + Y   YP ++   +  K      
Sbjct: 137 RVWFKNRRAKWRKRERNQQAE-LCKNGFGPQFNGLMQPYDDMYPGYSYNNWAAK-----G 190

Query: 543 ILEDSFLKSSFPTQAELDRLRVETKLSRREIDSWFSERRKLRD-SMEQAVLDSMGSGKKG 601
           +   S    SFP     + + V    S+    S FS    +   SM  +++ S  +G  G
Sbjct: 191 LTSASLSTKSFPF---FNSMNVNPLSSQ----SMFSPPNSISSMSMSSSMVPSAVTGVPG 243

Query: 602 QDVGAPNGALSRLDQLSGAQLTSSLPSPS 630
             +     +L+ L+ LS   L S++P+P+
Sbjct: 244 SSL----NSLNNLNNLSSPSLNSAVPTPA 268



 Score = 36.2 bits (82), Expect = 0.13
 Identities = 28/112 (25%), Positives = 46/112 (41%), Gaps = 21/112 (18%)

Query: 586 SMEQAVLDSMGSGKKGQDVGAPNGALSRLDQLSGAQLTSSLPSPSPAIAKSQEQVHLLRS 645
           S E A  D    GK  +DVGA + +  +  +      TS             +Q+  L +
Sbjct: 64  SPEAAEKDKSQQGKN-EDVGAEDPSKKKRQRRQRTHFTS-------------QQLQELEA 109

Query: 646 TFARTQWPTPQEYDQLAAKTGLVRTEIVRWFKENRCLLKTGTVKWMEQYQHQ 697
           TF R ++P     +++A  T L    +  WFK  R        KW ++ ++Q
Sbjct: 110 TFQRNRYPDMSTREEIAVWTNLTEARVRVWFKNRR-------AKWRKRERNQ 154


>gi|239744249 PREDICTED: similar to double homeobox, 4 [Homo
           sapiens]
          Length = 483

 Score = 42.7 bits (99), Expect = 0.001
 Identities = 45/189 (23%), Positives = 70/189 (37%), Gaps = 31/189 (16%)

Query: 403 HGQKRPLVTPQAAPEPKRPHIAQVPEPPPKVANPPLTPASDRKK-----TKEQIAHLKAS 457
           HG     + P+ + +  RP +  +  P P  +  P       ++     T  Q   L+A 
Sbjct: 40  HGSPPASLCPRPSVK-LRPGLTAMALPTPSDSTLPAEARGRGRRRRLVWTPSQSEALRAC 98

Query: 458 FLQSQFPDDAEVYRLIEVTGLARSEIKKWFSDHRYRCQRGIVHITSESLAKDQLAIAASR 517
           F ++ +P  A   RL +  G+    ++ WF + R R  R                    +
Sbjct: 99  FERNPYPGIATRERLAQAIGIPEPRVQIWFQNERSRQLR--------------------Q 138

Query: 518 HGRTYHAYPDF-APQKFKEK----TQGQVKILEDSFLKSSFPTQAELDRLRVETKLSRRE 572
           H R    +P    P + + K    T  Q  +L  +F K  FP  A  + L  ET L    
Sbjct: 139 HRRESRPWPGRRGPPEGRRKRTAVTGSQTALLLRAFEKDRFPGIAAREELARETGLPESR 198

Query: 573 IDSWFSERR 581
           I  WF  RR
Sbjct: 199 IQIWFQNRR 207



 Score = 32.7 bits (73), Expect = 1.4
 Identities = 22/65 (33%), Positives = 27/65 (41%)

Query: 429 PPPKVANPPLTPASDRKKTKEQIAHLKASFLQSQFPDDAEVYRLIEVTGLARSEIKKWFS 488
           P P    PP         T  Q A L  +F + +FP  A    L   TGL  S I+ WF 
Sbjct: 145 PWPGRRGPPEGRRKRTAVTGSQTALLLRAFEKDRFPGIAAREELARETGLPESRIQIWFQ 204

Query: 489 DHRYR 493
           + R R
Sbjct: 205 NRRAR 209



 Score = 32.0 bits (71), Expect = 2.4
 Identities = 32/144 (22%), Positives = 51/144 (35%), Gaps = 24/144 (16%)

Query: 537 TQGQVKILEDSFLKSSFPTQAELDRLRVETKLSRREIDSWFSERRKLRDSMEQAVLDSMG 596
           T  Q + L   F ++ +P  A  +RL     +    +  WF   R  R   +        
Sbjct: 88  TPSQSEALRACFERNPYPGIATRERLAQAIGIPEPRVQIWFQNERS-RQLRQHRRESRPW 146

Query: 597 SGKKGQDVGAPNGALSRLDQLSGAQLTSSLPSPSPAIAKSQEQVHLLRSTFARTQWPTPQ 656
            G++G     P G   R                    A +  Q  LL   F + ++P   
Sbjct: 147 PGRRGP----PEGRRKRT-------------------AVTGSQTALLLRAFEKDRFPGIA 183

Query: 657 EYDQLAAKTGLVRTEIVRWFKENR 680
             ++LA +TGL  + I  WF+  R
Sbjct: 184 AREELARETGLPESRIQIWFQNRR 207



 Score = 30.4 bits (67), Expect = 7.1
 Identities = 14/43 (32%), Positives = 22/43 (51%)

Query: 275 ATMINSFNKFPYPTQAELSWLTAASKHPEEHIRIWFATQRLKH 317
           A ++ +F K  +P  A    L   +  PE  I+IWF  +R +H
Sbjct: 168 ALLLRAFEKDRFPGIAAREELARETGLPESRIQIWFQNRRARH 210


>gi|239744248 PREDICTED: similar to double homeobox, 4 [Homo
           sapiens]
          Length = 483

 Score = 42.7 bits (99), Expect = 0.001
 Identities = 45/189 (23%), Positives = 70/189 (37%), Gaps = 31/189 (16%)

Query: 403 HGQKRPLVTPQAAPEPKRPHIAQVPEPPPKVANPPLTPASDRKK-----TKEQIAHLKAS 457
           HG     + P+ + +  RP +  +  P P  +  P       ++     T  Q   L+A 
Sbjct: 40  HGSPPASLCPRPSVK-LRPGLTAMALPTPSDSTLPAEARGRGRRRRLVWTPSQSEALRAC 98

Query: 458 FLQSQFPDDAEVYRLIEVTGLARSEIKKWFSDHRYRCQRGIVHITSESLAKDQLAIAASR 517
           F ++ +P  A   RL +  G+    ++ WF + R R  R                    +
Sbjct: 99  FERNPYPGIATRERLAQAIGIPEPRVQIWFQNERSRQLR--------------------Q 138

Query: 518 HGRTYHAYPDF-APQKFKEK----TQGQVKILEDSFLKSSFPTQAELDRLRVETKLSRRE 572
           H R    +P    P + + K    T  Q  +L  +F K  FP  A  + L  ET L    
Sbjct: 139 HRRESRPWPGRRGPPEGRRKRTAVTGSQTALLLRAFEKDRFPGIAAREELARETGLPESR 198

Query: 573 IDSWFSERR 581
           I  WF  RR
Sbjct: 199 IQIWFQNRR 207



 Score = 32.7 bits (73), Expect = 1.4
 Identities = 22/65 (33%), Positives = 27/65 (41%)

Query: 429 PPPKVANPPLTPASDRKKTKEQIAHLKASFLQSQFPDDAEVYRLIEVTGLARSEIKKWFS 488
           P P    PP         T  Q A L  +F + +FP  A    L   TGL  S I+ WF 
Sbjct: 145 PWPGRRGPPEGRRKRTAVTGSQTALLLRAFEKDRFPGIAAREELARETGLPESRIQIWFQ 204

Query: 489 DHRYR 493
           + R R
Sbjct: 205 NRRAR 209



 Score = 32.0 bits (71), Expect = 2.4
 Identities = 32/144 (22%), Positives = 51/144 (35%), Gaps = 24/144 (16%)

Query: 537 TQGQVKILEDSFLKSSFPTQAELDRLRVETKLSRREIDSWFSERRKLRDSMEQAVLDSMG 596
           T  Q + L   F ++ +P  A  +RL     +    +  WF   R  R   +        
Sbjct: 88  TPSQSEALRACFERNPYPGIATRERLAQAIGIPEPRVQIWFQNERS-RQLRQHRRESRPW 146

Query: 597 SGKKGQDVGAPNGALSRLDQLSGAQLTSSLPSPSPAIAKSQEQVHLLRSTFARTQWPTPQ 656
            G++G     P G   R                    A +  Q  LL   F + ++P   
Sbjct: 147 PGRRGP----PEGRRKRT-------------------AVTGSQTALLLRAFEKDRFPGIA 183

Query: 657 EYDQLAAKTGLVRTEIVRWFKENR 680
             ++LA +TGL  + I  WF+  R
Sbjct: 184 AREELARETGLPESRIQIWFQNRR 207



 Score = 30.4 bits (67), Expect = 7.1
 Identities = 14/43 (32%), Positives = 22/43 (51%)

Query: 275 ATMINSFNKFPYPTQAELSWLTAASKHPEEHIRIWFATQRLKH 317
           A ++ +F K  +P  A    L   +  PE  I+IWF  +R +H
Sbjct: 168 ALLLRAFEKDRFPGIAAREELARETGLPESRIQIWFQNRRARH 210


>gi|239744246 PREDICTED: hypothetical protein XP_002343082 [Homo
           sapiens]
          Length = 483

 Score = 42.7 bits (99), Expect = 0.001
 Identities = 45/189 (23%), Positives = 70/189 (37%), Gaps = 31/189 (16%)

Query: 403 HGQKRPLVTPQAAPEPKRPHIAQVPEPPPKVANPPLTPASDRKK-----TKEQIAHLKAS 457
           HG     + P+ + +  RP +  +  P P  +  P       ++     T  Q   L+A 
Sbjct: 40  HGSPPASLCPRPSVK-LRPGLTAMALPTPSDSTLPAEARGRGRRRRLVWTPSQSEALRAC 98

Query: 458 FLQSQFPDDAEVYRLIEVTGLARSEIKKWFSDHRYRCQRGIVHITSESLAKDQLAIAASR 517
           F ++ +P  A   RL +  G+    ++ WF + R R  R                    +
Sbjct: 99  FERNPYPGIATRERLAQAIGIPEPRVQIWFQNERSRQLR--------------------Q 138

Query: 518 HGRTYHAYPDF-APQKFKEK----TQGQVKILEDSFLKSSFPTQAELDRLRVETKLSRRE 572
           H R    +P    P + + K    T  Q  +L  +F K  FP  A  + L  ET L    
Sbjct: 139 HRRESRPWPGRRGPPEGRRKRTAVTGSQTALLLRAFEKDRFPGIAAREELARETGLPESR 198

Query: 573 IDSWFSERR 581
           I  WF  RR
Sbjct: 199 IQIWFQNRR 207



 Score = 32.7 bits (73), Expect = 1.4
 Identities = 22/65 (33%), Positives = 27/65 (41%)

Query: 429 PPPKVANPPLTPASDRKKTKEQIAHLKASFLQSQFPDDAEVYRLIEVTGLARSEIKKWFS 488
           P P    PP         T  Q A L  +F + +FP  A    L   TGL  S I+ WF 
Sbjct: 145 PWPGRRGPPEGRRKRTAVTGSQTALLLRAFEKDRFPGIAAREELARETGLPESRIQIWFQ 204

Query: 489 DHRYR 493
           + R R
Sbjct: 205 NRRAR 209



 Score = 32.0 bits (71), Expect = 2.4
 Identities = 32/144 (22%), Positives = 51/144 (35%), Gaps = 24/144 (16%)

Query: 537 TQGQVKILEDSFLKSSFPTQAELDRLRVETKLSRREIDSWFSERRKLRDSMEQAVLDSMG 596
           T  Q + L   F ++ +P  A  +RL     +    +  WF   R  R   +        
Sbjct: 88  TPSQSEALRACFERNPYPGIATRERLAQAIGIPEPRVQIWFQNERS-RQLRQHRRESRPW 146

Query: 597 SGKKGQDVGAPNGALSRLDQLSGAQLTSSLPSPSPAIAKSQEQVHLLRSTFARTQWPTPQ 656
            G++G     P G   R                    A +  Q  LL   F + ++P   
Sbjct: 147 PGRRGP----PEGRRKRT-------------------AVTGSQTALLLRAFEKDRFPGIA 183

Query: 657 EYDQLAAKTGLVRTEIVRWFKENR 680
             ++LA +TGL  + I  WF+  R
Sbjct: 184 AREELARETGLPESRIQIWFQNRR 207



 Score = 30.4 bits (67), Expect = 7.1
 Identities = 14/43 (32%), Positives = 22/43 (51%)

Query: 275 ATMINSFNKFPYPTQAELSWLTAASKHPEEHIRIWFATQRLKH 317
           A ++ +F K  +P  A    L   +  PE  I+IWF  +R +H
Sbjct: 168 ALLLRAFEKDRFPGIAAREELARETGLPESRIQIWFQNRRARH 210


>gi|239744242 PREDICTED: similar to double homeobox, 4 [Homo
           sapiens]
          Length = 483

 Score = 42.7 bits (99), Expect = 0.001
 Identities = 45/189 (23%), Positives = 70/189 (37%), Gaps = 31/189 (16%)

Query: 403 HGQKRPLVTPQAAPEPKRPHIAQVPEPPPKVANPPLTPASDRKK-----TKEQIAHLKAS 457
           HG     + P+ + +  RP +  +  P P  +  P       ++     T  Q   L+A 
Sbjct: 40  HGSPPASLCPRPSVK-LRPGLTAMALPTPSDSTLPAEARGRGRRRRLVWTPSQSEALRAC 98

Query: 458 FLQSQFPDDAEVYRLIEVTGLARSEIKKWFSDHRYRCQRGIVHITSESLAKDQLAIAASR 517
           F ++ +P  A   RL +  G+    ++ WF + R R  R                    +
Sbjct: 99  FERNPYPGIATRERLAQAIGIPEPRVQIWFQNERSRQLR--------------------Q 138

Query: 518 HGRTYHAYPDF-APQKFKEK----TQGQVKILEDSFLKSSFPTQAELDRLRVETKLSRRE 572
           H R    +P    P + + K    T  Q  +L  +F K  FP  A  + L  ET L    
Sbjct: 139 HRRESRPWPGRRGPPEGRRKRTAVTGSQTALLLRAFEKDRFPGIAAREELARETGLPESR 198

Query: 573 IDSWFSERR 581
           I  WF  RR
Sbjct: 199 IQIWFQNRR 207



 Score = 32.7 bits (73), Expect = 1.4
 Identities = 22/65 (33%), Positives = 27/65 (41%)

Query: 429 PPPKVANPPLTPASDRKKTKEQIAHLKASFLQSQFPDDAEVYRLIEVTGLARSEIKKWFS 488
           P P    PP         T  Q A L  +F + +FP  A    L   TGL  S I+ WF 
Sbjct: 145 PWPGRRGPPEGRRKRTAVTGSQTALLLRAFEKDRFPGIAAREELARETGLPESRIQIWFQ 204

Query: 489 DHRYR 493
           + R R
Sbjct: 205 NRRAR 209



 Score = 32.0 bits (71), Expect = 2.4
 Identities = 32/144 (22%), Positives = 51/144 (35%), Gaps = 24/144 (16%)

Query: 537 TQGQVKILEDSFLKSSFPTQAELDRLRVETKLSRREIDSWFSERRKLRDSMEQAVLDSMG 596
           T  Q + L   F ++ +P  A  +RL     +    +  WF   R  R   +        
Sbjct: 88  TPSQSEALRACFERNPYPGIATRERLAQAIGIPEPRVQIWFQNERS-RQLRQHRRESRPW 146

Query: 597 SGKKGQDVGAPNGALSRLDQLSGAQLTSSLPSPSPAIAKSQEQVHLLRSTFARTQWPTPQ 656
            G++G     P G   R                    A +  Q  LL   F + ++P   
Sbjct: 147 PGRRGP----PEGRRKRT-------------------AVTGSQTALLLRAFEKDRFPGIA 183

Query: 657 EYDQLAAKTGLVRTEIVRWFKENR 680
             ++LA +TGL  + I  WF+  R
Sbjct: 184 AREELARETGLPESRIQIWFQNRR 207



 Score = 30.4 bits (67), Expect = 7.1
 Identities = 14/43 (32%), Positives = 22/43 (51%)

Query: 275 ATMINSFNKFPYPTQAELSWLTAASKHPEEHIRIWFATQRLKH 317
           A ++ +F K  +P  A    L   +  PE  I+IWF  +R +H
Sbjct: 168 ALLLRAFEKDRFPGIAAREELARETGLPESRIQIWFQNRRARH 210


>gi|239744240 PREDICTED: similar to double homeobox, 4 [Homo
           sapiens]
          Length = 483

 Score = 42.7 bits (99), Expect = 0.001
 Identities = 45/189 (23%), Positives = 70/189 (37%), Gaps = 31/189 (16%)

Query: 403 HGQKRPLVTPQAAPEPKRPHIAQVPEPPPKVANPPLTPASDRKK-----TKEQIAHLKAS 457
           HG     + P+ + +  RP +  +  P P  +  P       ++     T  Q   L+A 
Sbjct: 40  HGSPPASLCPRPSVK-LRPGLTAMALPTPSDSTLPAEARGRGRRRRLVWTPSQSEALRAC 98

Query: 458 FLQSQFPDDAEVYRLIEVTGLARSEIKKWFSDHRYRCQRGIVHITSESLAKDQLAIAASR 517
           F ++ +P  A   RL +  G+    ++ WF + R R  R                    +
Sbjct: 99  FERNPYPGIATRERLAQAIGIPEPRVQIWFQNERSRQLR--------------------Q 138

Query: 518 HGRTYHAYPDF-APQKFKEK----TQGQVKILEDSFLKSSFPTQAELDRLRVETKLSRRE 572
           H R    +P    P + + K    T  Q  +L  +F K  FP  A  + L  ET L    
Sbjct: 139 HRRESRPWPGRRGPPEGRRKRTAVTGSQTALLLRAFEKDRFPGIAAREELARETGLPESR 198

Query: 573 IDSWFSERR 581
           I  WF  RR
Sbjct: 199 IQIWFQNRR 207



 Score = 32.7 bits (73), Expect = 1.4
 Identities = 22/65 (33%), Positives = 27/65 (41%)

Query: 429 PPPKVANPPLTPASDRKKTKEQIAHLKASFLQSQFPDDAEVYRLIEVTGLARSEIKKWFS 488
           P P    PP         T  Q A L  +F + +FP  A    L   TGL  S I+ WF 
Sbjct: 145 PWPGRRGPPEGRRKRTAVTGSQTALLLRAFEKDRFPGIAAREELARETGLPESRIQIWFQ 204

Query: 489 DHRYR 493
           + R R
Sbjct: 205 NRRAR 209



 Score = 32.0 bits (71), Expect = 2.4
 Identities = 32/144 (22%), Positives = 51/144 (35%), Gaps = 24/144 (16%)

Query: 537 TQGQVKILEDSFLKSSFPTQAELDRLRVETKLSRREIDSWFSERRKLRDSMEQAVLDSMG 596
           T  Q + L   F ++ +P  A  +RL     +    +  WF   R  R   +        
Sbjct: 88  TPSQSEALRACFERNPYPGIATRERLAQAIGIPEPRVQIWFQNERS-RQLRQHRRESRPW 146

Query: 597 SGKKGQDVGAPNGALSRLDQLSGAQLTSSLPSPSPAIAKSQEQVHLLRSTFARTQWPTPQ 656
            G++G     P G   R                    A +  Q  LL   F + ++P   
Sbjct: 147 PGRRGP----PEGRRKRT-------------------AVTGSQTALLLRAFEKDRFPGIA 183

Query: 657 EYDQLAAKTGLVRTEIVRWFKENR 680
             ++LA +TGL  + I  WF+  R
Sbjct: 184 AREELARETGLPESRIQIWFQNRR 207



 Score = 30.4 bits (67), Expect = 7.1
 Identities = 14/43 (32%), Positives = 22/43 (51%)

Query: 275 ATMINSFNKFPYPTQAELSWLTAASKHPEEHIRIWFATQRLKH 317
           A ++ +F K  +P  A    L   +  PE  I+IWF  +R +H
Sbjct: 168 ALLLRAFEKDRFPGIAAREELARETGLPESRIQIWFQNRRARH 210


>gi|239742468 PREDICTED: double homeobox, 4-like [Homo sapiens]
          Length = 485

 Score = 42.7 bits (99), Expect = 0.001
 Identities = 47/190 (24%), Positives = 70/190 (36%), Gaps = 33/190 (17%)

Query: 403 HGQKRPLVTPQAAPEPK-RPHIAQVPEPPPKVANPPLTPASDRKK-----TKEQIAHLKA 456
           HG     + P+  P  K RP +  +  P P  +  P       ++     T  Q   L+A
Sbjct: 40  HGSPPASLCPR--PSVKFRPGLTAMALPTPSDSTLPAEARGRGRRRRLVWTPSQSEALRA 97

Query: 457 SFLQSQFPDDAEVYRLIEVTGLARSEIKKWFSDHRYRCQRGIVHITSESLAKDQLAIAAS 516
            F ++ +P  A   RL +  G+    ++ WF + R R  R                    
Sbjct: 98  CFERNPYPGIATRERLAQAIGIPEPRVQIWFQNERSRQLR-------------------- 137

Query: 517 RHGRTYHAYPDF-APQKFKEK----TQGQVKILEDSFLKSSFPTQAELDRLRVETKLSRR 571
           +H R    +P    P + + K    T  Q  +L  +F K  FP  A  + L  ET L   
Sbjct: 138 QHRRESRPWPGRRGPPEGRRKRTAVTGSQTALLLRAFEKDRFPGIAAREELARETGLPES 197

Query: 572 EIDSWFSERR 581
            I  WF  RR
Sbjct: 198 RIQIWFQNRR 207



 Score = 32.7 bits (73), Expect = 1.4
 Identities = 22/65 (33%), Positives = 27/65 (41%)

Query: 429 PPPKVANPPLTPASDRKKTKEQIAHLKASFLQSQFPDDAEVYRLIEVTGLARSEIKKWFS 488
           P P    PP         T  Q A L  +F + +FP  A    L   TGL  S I+ WF 
Sbjct: 145 PWPGRRGPPEGRRKRTAVTGSQTALLLRAFEKDRFPGIAAREELARETGLPESRIQIWFQ 204

Query: 489 DHRYR 493
           + R R
Sbjct: 205 NRRAR 209



 Score = 32.0 bits (71), Expect = 2.4
 Identities = 32/144 (22%), Positives = 51/144 (35%), Gaps = 24/144 (16%)

Query: 537 TQGQVKILEDSFLKSSFPTQAELDRLRVETKLSRREIDSWFSERRKLRDSMEQAVLDSMG 596
           T  Q + L   F ++ +P  A  +RL     +    +  WF   R  R   +        
Sbjct: 88  TPSQSEALRACFERNPYPGIATRERLAQAIGIPEPRVQIWFQNERS-RQLRQHRRESRPW 146

Query: 597 SGKKGQDVGAPNGALSRLDQLSGAQLTSSLPSPSPAIAKSQEQVHLLRSTFARTQWPTPQ 656
            G++G     P G   R                    A +  Q  LL   F + ++P   
Sbjct: 147 PGRRGP----PEGRRKRT-------------------AVTGSQTALLLRAFEKDRFPGIA 183

Query: 657 EYDQLAAKTGLVRTEIVRWFKENR 680
             ++LA +TGL  + I  WF+  R
Sbjct: 184 AREELARETGLPESRIQIWFQNRR 207



 Score = 30.4 bits (67), Expect = 7.1
 Identities = 14/43 (32%), Positives = 22/43 (51%)

Query: 275 ATMINSFNKFPYPTQAELSWLTAASKHPEEHIRIWFATQRLKH 317
           A ++ +F K  +P  A    L   +  PE  I+IWF  +R +H
Sbjct: 168 ALLLRAFEKDRFPGIAAREELARETGLPESRIQIWFQNRRARH 210


>gi|239742467 PREDICTED: double homeobox, 4-like [Homo sapiens]
          Length = 483

 Score = 42.7 bits (99), Expect = 0.001
 Identities = 47/190 (24%), Positives = 70/190 (36%), Gaps = 33/190 (17%)

Query: 403 HGQKRPLVTPQAAPEPK-RPHIAQVPEPPPKVANPPLTPASDRKK-----TKEQIAHLKA 456
           HG     + P+  P  K RP +  +  P P  +  P       ++     T  Q   L+A
Sbjct: 40  HGSPPASLCPR--PSVKFRPGLTAMALPTPSDSTLPAEARGRGRRRRLVWTPSQSEALRA 97

Query: 457 SFLQSQFPDDAEVYRLIEVTGLARSEIKKWFSDHRYRCQRGIVHITSESLAKDQLAIAAS 516
            F ++ +P  A   RL +  G+    ++ WF + R R  R                    
Sbjct: 98  CFERNPYPGIATRERLAQAIGIPEPRVQIWFQNERSRQLR-------------------- 137

Query: 517 RHGRTYHAYPDF-APQKFKEK----TQGQVKILEDSFLKSSFPTQAELDRLRVETKLSRR 571
           +H R    +P    P + + K    T  Q  +L  +F K  FP  A  + L  ET L   
Sbjct: 138 QHRRESRPWPGRRGPPEGRRKRTAVTGSQTALLLRAFEKDRFPGIAAREELARETGLPES 197

Query: 572 EIDSWFSERR 581
            I  WF  RR
Sbjct: 198 RIQIWFQNRR 207



 Score = 32.7 bits (73), Expect = 1.4
 Identities = 22/65 (33%), Positives = 27/65 (41%)

Query: 429 PPPKVANPPLTPASDRKKTKEQIAHLKASFLQSQFPDDAEVYRLIEVTGLARSEIKKWFS 488
           P P    PP         T  Q A L  +F + +FP  A    L   TGL  S I+ WF 
Sbjct: 145 PWPGRRGPPEGRRKRTAVTGSQTALLLRAFEKDRFPGIAAREELARETGLPESRIQIWFQ 204

Query: 489 DHRYR 493
           + R R
Sbjct: 205 NRRAR 209



 Score = 32.0 bits (71), Expect = 2.4
 Identities = 32/144 (22%), Positives = 51/144 (35%), Gaps = 24/144 (16%)

Query: 537 TQGQVKILEDSFLKSSFPTQAELDRLRVETKLSRREIDSWFSERRKLRDSMEQAVLDSMG 596
           T  Q + L   F ++ +P  A  +RL     +    +  WF   R  R   +        
Sbjct: 88  TPSQSEALRACFERNPYPGIATRERLAQAIGIPEPRVQIWFQNERS-RQLRQHRRESRPW 146

Query: 597 SGKKGQDVGAPNGALSRLDQLSGAQLTSSLPSPSPAIAKSQEQVHLLRSTFARTQWPTPQ 656
            G++G     P G   R                    A +  Q  LL   F + ++P   
Sbjct: 147 PGRRGP----PEGRRKRT-------------------AVTGSQTALLLRAFEKDRFPGIA 183

Query: 657 EYDQLAAKTGLVRTEIVRWFKENR 680
             ++LA +TGL  + I  WF+  R
Sbjct: 184 AREELARETGLPESRIQIWFQNRR 207



 Score = 30.4 bits (67), Expect = 7.1
 Identities = 14/43 (32%), Positives = 22/43 (51%)

Query: 275 ATMINSFNKFPYPTQAELSWLTAASKHPEEHIRIWFATQRLKH 317
           A ++ +F K  +P  A    L   +  PE  I+IWF  +R +H
Sbjct: 168 ALLLRAFEKDRFPGIAAREELARETGLPESRIQIWFQNRRARH 210


>gi|194272172 double homeobox, 4 [Homo sapiens]
          Length = 485

 Score = 42.7 bits (99), Expect = 0.001
 Identities = 47/190 (24%), Positives = 70/190 (36%), Gaps = 33/190 (17%)

Query: 403 HGQKRPLVTPQAAPEPK-RPHIAQVPEPPPKVANPPLTPASDRKK-----TKEQIAHLKA 456
           HG     + P+  P  K RP +  +  P P  +  P       ++     T  Q   L+A
Sbjct: 40  HGSPPASLCPR--PSVKFRPGLTAMALPTPSDSTLPAEARGRGRRRRLVWTPSQSEALRA 97

Query: 457 SFLQSQFPDDAEVYRLIEVTGLARSEIKKWFSDHRYRCQRGIVHITSESLAKDQLAIAAS 516
            F ++ +P  A   RL +  G+    ++ WF + R R  R                    
Sbjct: 98  CFERNPYPGIATRERLAQAIGIPEPRVQIWFQNERSRQLR-------------------- 137

Query: 517 RHGRTYHAYPDF-APQKFKEK----TQGQVKILEDSFLKSSFPTQAELDRLRVETKLSRR 571
           +H R    +P    P + + K    T  Q  +L  +F K  FP  A  + L  ET L   
Sbjct: 138 QHRRESRPWPGRRGPPEGRRKRTAVTGSQTALLLRAFEKDRFPGIAAREELARETGLPES 197

Query: 572 EIDSWFSERR 581
            I  WF  RR
Sbjct: 198 RIQIWFQNRR 207



 Score = 32.7 bits (73), Expect = 1.4
 Identities = 22/65 (33%), Positives = 27/65 (41%)

Query: 429 PPPKVANPPLTPASDRKKTKEQIAHLKASFLQSQFPDDAEVYRLIEVTGLARSEIKKWFS 488
           P P    PP         T  Q A L  +F + +FP  A    L   TGL  S I+ WF 
Sbjct: 145 PWPGRRGPPEGRRKRTAVTGSQTALLLRAFEKDRFPGIAAREELARETGLPESRIQIWFQ 204

Query: 489 DHRYR 493
           + R R
Sbjct: 205 NRRAR 209



 Score = 32.0 bits (71), Expect = 2.4
 Identities = 32/144 (22%), Positives = 51/144 (35%), Gaps = 24/144 (16%)

Query: 537 TQGQVKILEDSFLKSSFPTQAELDRLRVETKLSRREIDSWFSERRKLRDSMEQAVLDSMG 596
           T  Q + L   F ++ +P  A  +RL     +    +  WF   R  R   +        
Sbjct: 88  TPSQSEALRACFERNPYPGIATRERLAQAIGIPEPRVQIWFQNERS-RQLRQHRRESRPW 146

Query: 597 SGKKGQDVGAPNGALSRLDQLSGAQLTSSLPSPSPAIAKSQEQVHLLRSTFARTQWPTPQ 656
            G++G     P G   R                    A +  Q  LL   F + ++P   
Sbjct: 147 PGRRGP----PEGRRKRT-------------------AVTGSQTALLLRAFEKDRFPGIA 183

Query: 657 EYDQLAAKTGLVRTEIVRWFKENR 680
             ++LA +TGL  + I  WF+  R
Sbjct: 184 AREELARETGLPESRIQIWFQNRR 207



 Score = 30.4 bits (67), Expect = 7.1
 Identities = 14/43 (32%), Positives = 22/43 (51%)

Query: 275 ATMINSFNKFPYPTQAELSWLTAASKHPEEHIRIWFATQRLKH 317
           A ++ +F K  +P  A    L   +  PE  I+IWF  +R +H
Sbjct: 168 ALLLRAFEKDRFPGIAAREELARETGLPESRIQIWFQNRRARH 210


>gi|194272217 double homeobox, 4-like [Homo sapiens]
          Length = 485

 Score = 42.7 bits (99), Expect = 0.001
 Identities = 47/190 (24%), Positives = 70/190 (36%), Gaps = 33/190 (17%)

Query: 403 HGQKRPLVTPQAAPEPK-RPHIAQVPEPPPKVANPPLTPASDRKK-----TKEQIAHLKA 456
           HG     + P+  P  K RP +  +  P P  +  P       ++     T  Q   L+A
Sbjct: 40  HGSPPASLCPR--PSVKFRPGLTAMALPTPSDSTLPAEARGRGRRRRLVWTPSQSEALRA 97

Query: 457 SFLQSQFPDDAEVYRLIEVTGLARSEIKKWFSDHRYRCQRGIVHITSESLAKDQLAIAAS 516
            F ++ +P  A   RL +  G+    ++ WF + R R  R                    
Sbjct: 98  CFERNPYPGIATRERLAQAIGIPEPRVQIWFQNERSRQLR-------------------- 137

Query: 517 RHGRTYHAYPDF-APQKFKEK----TQGQVKILEDSFLKSSFPTQAELDRLRVETKLSRR 571
           +H R    +P    P + + K    T  Q  +L  +F K  FP  A  + L  ET L   
Sbjct: 138 QHRRESRPWPGRRGPPEGRRKRTAVTGSQTALLLRAFEKDRFPGIAAREELARETGLPES 197

Query: 572 EIDSWFSERR 581
            I  WF  RR
Sbjct: 198 RIQIWFQNRR 207



 Score = 32.7 bits (73), Expect = 1.4
 Identities = 22/65 (33%), Positives = 27/65 (41%)

Query: 429 PPPKVANPPLTPASDRKKTKEQIAHLKASFLQSQFPDDAEVYRLIEVTGLARSEIKKWFS 488
           P P    PP         T  Q A L  +F + +FP  A    L   TGL  S I+ WF 
Sbjct: 145 PWPGRRGPPEGRRKRTAVTGSQTALLLRAFEKDRFPGIAAREELARETGLPESRIQIWFQ 204

Query: 489 DHRYR 493
           + R R
Sbjct: 205 NRRAR 209



 Score = 32.0 bits (71), Expect = 2.4
 Identities = 32/144 (22%), Positives = 51/144 (35%), Gaps = 24/144 (16%)

Query: 537 TQGQVKILEDSFLKSSFPTQAELDRLRVETKLSRREIDSWFSERRKLRDSMEQAVLDSMG 596
           T  Q + L   F ++ +P  A  +RL     +    +  WF   R  R   +        
Sbjct: 88  TPSQSEALRACFERNPYPGIATRERLAQAIGIPEPRVQIWFQNERS-RQLRQHRRESRPW 146

Query: 597 SGKKGQDVGAPNGALSRLDQLSGAQLTSSLPSPSPAIAKSQEQVHLLRSTFARTQWPTPQ 656
            G++G     P G   R                    A +  Q  LL   F + ++P   
Sbjct: 147 PGRRGP----PEGRRKRT-------------------AVTGSQTALLLRAFEKDRFPGIA 183

Query: 657 EYDQLAAKTGLVRTEIVRWFKENR 680
             ++LA +TGL  + I  WF+  R
Sbjct: 184 AREELARETGLPESRIQIWFQNRR 207



 Score = 30.4 bits (67), Expect = 7.1
 Identities = 14/43 (32%), Positives = 22/43 (51%)

Query: 275 ATMINSFNKFPYPTQAELSWLTAASKHPEEHIRIWFATQRLKH 317
           A ++ +F K  +P  A    L   +  PE  I+IWF  +R +H
Sbjct: 168 ALLLRAFEKDRFPGIAAREELARETGLPESRIQIWFQNRRARH 210


>gi|194272216 double homeobox, 4-like [Homo sapiens]
          Length = 485

 Score = 42.7 bits (99), Expect = 0.001
 Identities = 47/190 (24%), Positives = 70/190 (36%), Gaps = 33/190 (17%)

Query: 403 HGQKRPLVTPQAAPEPK-RPHIAQVPEPPPKVANPPLTPASDRKK-----TKEQIAHLKA 456
           HG     + P+  P  K RP +  +  P P  +  P       ++     T  Q   L+A
Sbjct: 40  HGSPPASLCPR--PSVKFRPGLTAMALPTPSDSTLPAEARGRGRRRRLVWTPSQSEALRA 97

Query: 457 SFLQSQFPDDAEVYRLIEVTGLARSEIKKWFSDHRYRCQRGIVHITSESLAKDQLAIAAS 516
            F ++ +P  A   RL +  G+    ++ WF + R R  R                    
Sbjct: 98  CFERNPYPGIATRERLAQAIGIPEPRVQIWFQNERSRQLR-------------------- 137

Query: 517 RHGRTYHAYPDF-APQKFKEK----TQGQVKILEDSFLKSSFPTQAELDRLRVETKLSRR 571
           +H R    +P    P + + K    T  Q  +L  +F K  FP  A  + L  ET L   
Sbjct: 138 QHRRESRPWPGRRGPPEGRRKRTAVTGSQTALLLRAFEKDRFPGIAAREELARETGLPES 197

Query: 572 EIDSWFSERR 581
            I  WF  RR
Sbjct: 198 RIQIWFQNRR 207



 Score = 32.7 bits (73), Expect = 1.4
 Identities = 22/65 (33%), Positives = 27/65 (41%)

Query: 429 PPPKVANPPLTPASDRKKTKEQIAHLKASFLQSQFPDDAEVYRLIEVTGLARSEIKKWFS 488
           P P    PP         T  Q A L  +F + +FP  A    L   TGL  S I+ WF 
Sbjct: 145 PWPGRRGPPEGRRKRTAVTGSQTALLLRAFEKDRFPGIAAREELARETGLPESRIQIWFQ 204

Query: 489 DHRYR 493
           + R R
Sbjct: 205 NRRAR 209



 Score = 32.0 bits (71), Expect = 2.4
 Identities = 32/144 (22%), Positives = 51/144 (35%), Gaps = 24/144 (16%)

Query: 537 TQGQVKILEDSFLKSSFPTQAELDRLRVETKLSRREIDSWFSERRKLRDSMEQAVLDSMG 596
           T  Q + L   F ++ +P  A  +RL     +    +  WF   R  R   +        
Sbjct: 88  TPSQSEALRACFERNPYPGIATRERLAQAIGIPEPRVQIWFQNERS-RQLRQHRRESRPW 146

Query: 597 SGKKGQDVGAPNGALSRLDQLSGAQLTSSLPSPSPAIAKSQEQVHLLRSTFARTQWPTPQ 656
            G++G     P G   R                    A +  Q  LL   F + ++P   
Sbjct: 147 PGRRGP----PEGRRKRT-------------------AVTGSQTALLLRAFEKDRFPGIA 183

Query: 657 EYDQLAAKTGLVRTEIVRWFKENR 680
             ++LA +TGL  + I  WF+  R
Sbjct: 184 AREELARETGLPESRIQIWFQNRR 207



 Score = 30.4 bits (67), Expect = 7.1
 Identities = 14/43 (32%), Positives = 22/43 (51%)

Query: 275 ATMINSFNKFPYPTQAELSWLTAASKHPEEHIRIWFATQRLKH 317
           A ++ +F K  +P  A    L   +  PE  I+IWF  +R +H
Sbjct: 168 ALLLRAFEKDRFPGIAAREELARETGLPESRIQIWFQNRRARH 210


>gi|194272215 double homeobox, 4-like [Homo sapiens]
          Length = 485

 Score = 42.7 bits (99), Expect = 0.001
 Identities = 47/190 (24%), Positives = 70/190 (36%), Gaps = 33/190 (17%)

Query: 403 HGQKRPLVTPQAAPEPK-RPHIAQVPEPPPKVANPPLTPASDRKK-----TKEQIAHLKA 456
           HG     + P+  P  K RP +  +  P P  +  P       ++     T  Q   L+A
Sbjct: 40  HGSPPASLCPR--PSVKFRPGLTAMALPTPSDSTLPAEARGRGRRRRLVWTPSQSEALRA 97

Query: 457 SFLQSQFPDDAEVYRLIEVTGLARSEIKKWFSDHRYRCQRGIVHITSESLAKDQLAIAAS 516
            F ++ +P  A   RL +  G+    ++ WF + R R  R                    
Sbjct: 98  CFERNPYPGIATRERLAQAIGIPEPRVQIWFQNERSRQLR-------------------- 137

Query: 517 RHGRTYHAYPDF-APQKFKEK----TQGQVKILEDSFLKSSFPTQAELDRLRVETKLSRR 571
           +H R    +P    P + + K    T  Q  +L  +F K  FP  A  + L  ET L   
Sbjct: 138 QHRRESRPWPGRRGPPEGRRKRTAVTGSQTALLLRAFEKDRFPGIAAREELARETGLPES 197

Query: 572 EIDSWFSERR 581
            I  WF  RR
Sbjct: 198 RIQIWFQNRR 207



 Score = 32.7 bits (73), Expect = 1.4
 Identities = 22/65 (33%), Positives = 27/65 (41%)

Query: 429 PPPKVANPPLTPASDRKKTKEQIAHLKASFLQSQFPDDAEVYRLIEVTGLARSEIKKWFS 488
           P P    PP         T  Q A L  +F + +FP  A    L   TGL  S I+ WF 
Sbjct: 145 PWPGRRGPPEGRRKRTAVTGSQTALLLRAFEKDRFPGIAAREELARETGLPESRIQIWFQ 204

Query: 489 DHRYR 493
           + R R
Sbjct: 205 NRRAR 209



 Score = 32.0 bits (71), Expect = 2.4
 Identities = 32/144 (22%), Positives = 51/144 (35%), Gaps = 24/144 (16%)

Query: 537 TQGQVKILEDSFLKSSFPTQAELDRLRVETKLSRREIDSWFSERRKLRDSMEQAVLDSMG 596
           T  Q + L   F ++ +P  A  +RL     +    +  WF   R  R   +        
Sbjct: 88  TPSQSEALRACFERNPYPGIATRERLAQAIGIPEPRVQIWFQNERS-RQLRQHRRESRPW 146

Query: 597 SGKKGQDVGAPNGALSRLDQLSGAQLTSSLPSPSPAIAKSQEQVHLLRSTFARTQWPTPQ 656
            G++G     P G   R                    A +  Q  LL   F + ++P   
Sbjct: 147 PGRRGP----PEGRRKRT-------------------AVTGSQTALLLRAFEKDRFPGIA 183

Query: 657 EYDQLAAKTGLVRTEIVRWFKENR 680
             ++LA +TGL  + I  WF+  R
Sbjct: 184 AREELARETGLPESRIQIWFQNRR 207



 Score = 30.4 bits (67), Expect = 7.1
 Identities = 14/43 (32%), Positives = 22/43 (51%)

Query: 275 ATMINSFNKFPYPTQAELSWLTAASKHPEEHIRIWFATQRLKH 317
           A ++ +F K  +P  A    L   +  PE  I+IWF  +R +H
Sbjct: 168 ALLLRAFEKDRFPGIAAREELARETGLPESRIQIWFQNRRARH 210


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.311    0.127    0.367 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 34,663,947
Number of Sequences: 37866
Number of extensions: 1726303
Number of successful extensions: 9847
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 163
Number of HSP's successfully gapped in prelim test: 302
Number of HSP's that attempted gapping in prelim test: 8155
Number of HSP's gapped (non-prelim): 1803
length of query: 837
length of database: 18,247,518
effective HSP length: 111
effective length of query: 726
effective length of database: 14,044,392
effective search space: 10196228592
effective search space used: 10196228592
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 66 (30.0 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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