Guide to the Human Genome
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Search of human proteins with 7662340

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|7662340 MORC family CW-type zinc finger 2 [Homo sapiens]
         (970 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|7662340 MORC family CW-type zinc finger 2 [Homo sapiens]          1934   0.0  
gi|221625538 MORC family CW-type zinc finger 1 [Homo sapiens]         491   e-138
gi|145553976 zinc finger, CW type with coiled-coil domain 2 isof...   129   1e-29
gi|145553971 zinc finger, CW type with coiled-coil domain 2 isof...   129   1e-29
gi|28872812 MORC family CW-type zinc finger 3 [Homo sapiens]          121   3e-27
gi|110349719 titin isoform N2-A [Homo sapiens]                         64   7e-10
gi|163965366 nascent polypeptide-associated complex alpha subuni...    61   4e-09
gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens]     61   6e-09
gi|78042577 MAP7 domain containing 1 [Homo sapiens]                    59   2e-08
gi|189181724 proteoglycan 4 isoform D [Homo sapiens]                   58   5e-08
gi|189181722 proteoglycan 4 isoform C [Homo sapiens]                   58   5e-08
gi|189181720 proteoglycan 4 isoform B [Homo sapiens]                   58   5e-08
gi|67190163 proteoglycan 4 isoform A [Homo sapiens]                    58   5e-08
gi|9945318 MAX binding protein [Homo sapiens]                          52   4e-06
gi|149158690 HLA-B associated transcript-2 [Homo sapiens]              51   5e-06
gi|24431935 reticulon 4 isoform A [Homo sapiens]                       51   6e-06
gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens]         50   8e-06
gi|21040326 SON DNA-binding protein isoform F [Homo sapiens]           50   1e-05
gi|21040314 SON DNA-binding protein isoform B [Homo sapiens]           50   1e-05
gi|116284392 mucin 2 precursor [Homo sapiens]                          50   1e-05
gi|38788260 bromodomain PHD finger transcription factor isoform ...    49   2e-05
gi|32140760 collagen, type XXVII, alpha 1 [Homo sapiens]               49   2e-05
gi|33286442 BCL6 co-repressor-like 1 [Homo sapiens]                    49   2e-05
gi|149773456 hypothetical protein LOC643314 [Homo sapiens]             49   3e-05
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi...    49   3e-05
gi|21312134 mediator complex subunit 15 isoform b [Homo sapiens]       49   3e-05
gi|239751395 PREDICTED: hypothetical protein, partial [Homo sapi...    48   4e-05
gi|239745904 PREDICTED: hypothetical protein, partial [Homo sapi...    48   4e-05
gi|153792074 proline rich 12 [Homo sapiens]                            48   4e-05
gi|24431933 reticulon 4 isoform B [Homo sapiens]                       48   5e-05

>gi|7662340 MORC family CW-type zinc finger 2 [Homo sapiens]
          Length = 970

 Score = 1934 bits (5011), Expect = 0.0
 Identities = 970/970 (100%), Positives = 970/970 (100%)

Query: 1   MLCFLDDGAGMDPSDAASVIQFGKSAKRTPESTQIGQYGNGLKSGSMRIGKDFILFTKKE 60
           MLCFLDDGAGMDPSDAASVIQFGKSAKRTPESTQIGQYGNGLKSGSMRIGKDFILFTKKE
Sbjct: 1   MLCFLDDGAGMDPSDAASVIQFGKSAKRTPESTQIGQYGNGLKSGSMRIGKDFILFTKKE 60

Query: 61  DTMTCLFLSRTFHEEEGIDEVIVPLPTWNARTREPVTDNVEKFAIETELIYKYSPFRTEE 120
           DTMTCLFLSRTFHEEEGIDEVIVPLPTWNARTREPVTDNVEKFAIETELIYKYSPFRTEE
Sbjct: 61  DTMTCLFLSRTFHEEEGIDEVIVPLPTWNARTREPVTDNVEKFAIETELIYKYSPFRTEE 120

Query: 121 EVMTQFMKIPGDSGTLVIIFNLKLMDNGEPELDIISNPRDIQMAETSPEGTKPERRSFRA 180
           EVMTQFMKIPGDSGTLVIIFNLKLMDNGEPELDIISNPRDIQMAETSPEGTKPERRSFRA
Sbjct: 121 EVMTQFMKIPGDSGTLVIIFNLKLMDNGEPELDIISNPRDIQMAETSPEGTKPERRSFRA 180

Query: 181 YAAVLYIDPRMRIFIHGHKVQTKRLSCCLYKPRMYKYTSSRFKTRAEQEVKKAEHVARIA 240
           YAAVLYIDPRMRIFIHGHKVQTKRLSCCLYKPRMYKYTSSRFKTRAEQEVKKAEHVARIA
Sbjct: 181 YAAVLYIDPRMRIFIHGHKVQTKRLSCCLYKPRMYKYTSSRFKTRAEQEVKKAEHVARIA 240

Query: 241 EEKAREAESKARTLEVRLGGDLTRDSRVMLRQVQNRAITLRREADVKKRIKEAKQRALKE 300
           EEKAREAESKARTLEVRLGGDLTRDSRVMLRQVQNRAITLRREADVKKRIKEAKQRALKE
Sbjct: 241 EEKAREAESKARTLEVRLGGDLTRDSRVMLRQVQNRAITLRREADVKKRIKEAKQRALKE 300

Query: 301 PKELNFVFGVNIEHRDLDGMFIYNCSRLIKMYEKVGPQLEGGMACGGVVGVVDVPYLVLE 360
           PKELNFVFGVNIEHRDLDGMFIYNCSRLIKMYEKVGPQLEGGMACGGVVGVVDVPYLVLE
Sbjct: 301 PKELNFVFGVNIEHRDLDGMFIYNCSRLIKMYEKVGPQLEGGMACGGVVGVVDVPYLVLE 360

Query: 361 PTHNKQDFADAKEYRHLLRAMGEHLAQYWKDIAIAQRGIIKFWDEFGYLSANWNQPPSSE 420
           PTHNKQDFADAKEYRHLLRAMGEHLAQYWKDIAIAQRGIIKFWDEFGYLSANWNQPPSSE
Sbjct: 361 PTHNKQDFADAKEYRHLLRAMGEHLAQYWKDIAIAQRGIIKFWDEFGYLSANWNQPPSSE 420

Query: 421 LRYKRRRAMEIPTTIQCDLCLKWRTLPFQLSSVEKDYPDTWVCSMNPDPEQDRCEASEQK 480
           LRYKRRRAMEIPTTIQCDLCLKWRTLPFQLSSVEKDYPDTWVCSMNPDPEQDRCEASEQK
Sbjct: 421 LRYKRRRAMEIPTTIQCDLCLKWRTLPFQLSSVEKDYPDTWVCSMNPDPEQDRCEASEQK 480

Query: 481 QKVPLGTFRKDMKTQEEKQKQLTEKIRQQQEKLEALQKTTPIRSQADLKKLPLEVTTRPS 540
           QKVPLGTFRKDMKTQEEKQKQLTEKIRQQQEKLEALQKTTPIRSQADLKKLPLEVTTRPS
Sbjct: 481 QKVPLGTFRKDMKTQEEKQKQLTEKIRQQQEKLEALQKTTPIRSQADLKKLPLEVTTRPS 540

Query: 541 TEEPVRRPQRPRSPPLPAVIRNAPSRPPSLPTPRPASQPRKAPVISSTPKLPALAAREEA 600
           TEEPVRRPQRPRSPPLPAVIRNAPSRPPSLPTPRPASQPRKAPVISSTPKLPALAAREEA
Sbjct: 541 TEEPVRRPQRPRSPPLPAVIRNAPSRPPSLPTPRPASQPRKAPVISSTPKLPALAAREEA 600

Query: 601 STSRLLQPPEAPRKPANTLVKTASRPAPLVQQLSPSLLPNSKSPREVPSPKVIKTPVVKK 660
           STSRLLQPPEAPRKPANTLVKTASRPAPLVQQLSPSLLPNSKSPREVPSPKVIKTPVVKK
Sbjct: 601 STSRLLQPPEAPRKPANTLVKTASRPAPLVQQLSPSLLPNSKSPREVPSPKVIKTPVVKK 660

Query: 661 TESPIKLSPATPSRKRSVAVSDEEEVEEEAERRKERCKRGRFVVKEEKKDSNELSDSAGE 720
           TESPIKLSPATPSRKRSVAVSDEEEVEEEAERRKERCKRGRFVVKEEKKDSNELSDSAGE
Sbjct: 661 TESPIKLSPATPSRKRSVAVSDEEEVEEEAERRKERCKRGRFVVKEEKKDSNELSDSAGE 720

Query: 721 EDSADLKRAQKDKGLHVEVRVNREWYTGRVTAVEVGKHVVRWKVKFDYVPTDTTPRDRWV 780
           EDSADLKRAQKDKGLHVEVRVNREWYTGRVTAVEVGKHVVRWKVKFDYVPTDTTPRDRWV
Sbjct: 721 EDSADLKRAQKDKGLHVEVRVNREWYTGRVTAVEVGKHVVRWKVKFDYVPTDTTPRDRWV 780

Query: 781 EKGSEDVRLMKPPSPEHQSLDTQQEGGEEEVGPVAQQAIAVAEPSTSECLRIEPDTTALS 840
           EKGSEDVRLMKPPSPEHQSLDTQQEGGEEEVGPVAQQAIAVAEPSTSECLRIEPDTTALS
Sbjct: 781 EKGSEDVRLMKPPSPEHQSLDTQQEGGEEEVGPVAQQAIAVAEPSTSECLRIEPDTTALS 840

Query: 841 TNHETIDLLVQILRNCLRYFLPPSFPISKKQLSAMNSDELISFPLKEYFKQYEVGLQNLC 900
           TNHETIDLLVQILRNCLRYFLPPSFPISKKQLSAMNSDELISFPLKEYFKQYEVGLQNLC
Sbjct: 841 TNHETIDLLVQILRNCLRYFLPPSFPISKKQLSAMNSDELISFPLKEYFKQYEVGLQNLC 900

Query: 901 NSYQSRADSRAKASEESLRTSERKLRETEEKLQKLRTNIVALLQKVQEDIDINTDDELDA 960
           NSYQSRADSRAKASEESLRTSERKLRETEEKLQKLRTNIVALLQKVQEDIDINTDDELDA
Sbjct: 901 NSYQSRADSRAKASEESLRTSERKLRETEEKLQKLRTNIVALLQKVQEDIDINTDDELDA 960

Query: 961 YIEDLITKGD 970
           YIEDLITKGD
Sbjct: 961 YIEDLITKGD 970


>gi|221625538 MORC family CW-type zinc finger 1 [Homo sapiens]
          Length = 984

 Score =  491 bits (1263), Expect = e-138
 Identities = 257/518 (49%), Positives = 343/518 (66%), Gaps = 14/518 (2%)

Query: 1   MLCFLDDGAGMDPSDAASVIQFGKSAKRTPESTQIGQYGNGLKSGSMRIGKDFILFTKKE 60
           MLCFLDDG GM P +A+ +I FG+S KR      IGQYGNGLKSGSMRIGKDFILFTKKE
Sbjct: 62  MLCFLDDGCGMSPEEASDIIYFGRSKKRLSTLKFIGQYGNGLKSGSMRIGKDFILFTKKE 121

Query: 61  DTMTCLFLSRTFHEEEGIDEVIVPLPTWNARTREPVTDNVEKFAIETELIYKYSPFRTEE 120
           +TMTC+F S+TF EEE + EV+VP+P+W  RTRE VTD+ +KFA+E  +IYKYSPF+TE 
Sbjct: 122 ETMTCVFFSQTFCEEESLSEVVVPMPSWLIRTRESVTDDPQKFAMELSIIYKYSPFKTEA 181

Query: 121 EVMTQFMKIPGDSGTLVIIFNLKLMDNGEPELDIISNPRDIQMAETSPEGTKPERRSFRA 180
           E+M QF  I G  GTL++I+NLKL+ NGEPELD+ ++  DI MA    +   P R SFRA
Sbjct: 182 ELMQQFDVIYGKCGTLLVIYNLKLLLNGEPELDVKTDKEDILMAGALED--FPARWSFRA 239

Query: 181 YAAVLYIDPRMRIFIHGHKVQTKRLSCCLYKPRMYKYTSSRFKTRAEQEVKKAEHVARIA 240
           Y +VLY +P MRIFI   +V+TK L  CLY+PR Y Y +S FK   + EVKKAE   +IA
Sbjct: 240 YTSVLYFNPWMRIFIQAKRVKTKHLCYCLYRPRKYLYVTSSFKGAFKDEVKKAEEAVKIA 299

Query: 241 EEKAREAESKARTLEVRLGGDLTRDSRVMLRQVQNRAITLRREADVKKRIKEAKQRALKE 300
           E   +EA+ K    +        R S    + V  RA+    + + K++  + KQR LK 
Sbjct: 300 ESILKEAQIKVNQCD--------RTSLSSAKDVLQRAL---EDVEAKQKNLKEKQRELKT 348

Query: 301 PKELNFVFGVNIEHRDLDGMFIYNCSRLIKMYEKVGPQLEGGMACG-GVVGVVDVPYLVL 359
            + L+  +GVN+E+R   GMFIY+ +RLIKM+EKVG QL+     G GVVG+V++P  V+
Sbjct: 349 ARTLSLFYGVNVENRSQAGMFIYSNNRLIKMHEKVGSQLKLKSLLGAGVVGIVNIPLEVM 408

Query: 360 EPTHNKQDFADAKEYRHLLRAMGEHLAQYWKDIAIAQRGIIKFWDEFGYLSANWNQPPSS 419
           EP+HNKQ+F + +EY HLL+ MG++L QY KD  I  R +  F +EFGY +    + P +
Sbjct: 409 EPSHNKQEFLNVQEYNHLLKVMGQYLVQYCKDTGINNRNLTLFCNEFGYQNDIDVEKPLN 468

Query: 420 ELRYKRRRAMEIPTTIQCDLCLKWRTLPFQLSSVEKDYPDTWVCSMNPDPEQDRCEASEQ 479
             +Y+RR+AM IP  IQCDLCLKWR LP   +  EK++ D W+C+ NP+  ++ C   E 
Sbjct: 469 SFQYQRRQAMGIPFIIQCDLCLKWRVLPSSTNYQEKEFFDIWICANNPNRLENSCHQVEC 528

Query: 480 KQKVPLGTFRKDMKTQEEKQKQLTEKIRQQQEKLEALQ 517
              +PLGT      ++ EK+KQL E + + Q +L   Q
Sbjct: 529 LPSIPLGTMSTISPSKNEKEKQLRESVIKYQNRLAEQQ 566



 Score = 44.3 bits (103), Expect = 6e-04
 Identities = 43/161 (26%), Positives = 73/161 (45%), Gaps = 15/161 (9%)

Query: 821 VAEPSTSECLRI--EPDTTALSTNHETIDLLVQILRNCLRYFLPPSFPISKKQLSAMNSD 878
           +A  S S   ++   P ++  +   ET+  L   LR  L YF P     S+ +  A++ +
Sbjct: 791 IARVSVSGSCKVASSPASSQSTPVKETVRKLKSKLREILLYFFPEHQLPSELEEPALSCE 850

Query: 879 -----ELISFPLK--------EYFKQYEVGLQNLCNSYQSRADSRAKASEESLRTSERKL 925
                E ++  LK         Y  QYE  ++    S    +++R   +E SL   E K 
Sbjct: 851 LEQCPEQMNKKLKMCFNQIQNTYMVQYEKKIKRKLQSIIYDSNTRGIHNEISLGQCENKR 910

Query: 926 RETEEKLQKLRTNIVALLQKVQEDIDINTDDELDAYIEDLI 966
           + +E+KL+ LR  +  LLQK+Q        ++ D Y+E L+
Sbjct: 911 KISEDKLKNLRIKLALLLQKLQLGGPEGDLEQTDTYLEALL 951


>gi|145553976 zinc finger, CW type with coiled-coil domain 2 isoform
           a [Homo sapiens]
          Length = 937

 Score =  129 bits (325), Expect = 1e-29
 Identities = 84/228 (36%), Positives = 122/228 (53%), Gaps = 19/228 (8%)

Query: 2   LCFLDDGAGMDPSDAASVIQFGKSAKRTPEST-QIGQYGNGLKSGSMRIGKDFILFTKKE 60
           L F DDG GM P     ++ FG + K   +S   IG +GNG KSGSMR+GKD ++FTK  
Sbjct: 84  LTFTDDGCGMTPHKLHRMLSFGFTDKVIKKSQCPIGVFGNGFKSGSMRLGKDALVFTKNG 143

Query: 61  DTMTCLFLSRTFHEEEGIDEVIVPLPTWNARTREPVTDNVEKFAIETELIYKYSPFRTEE 120
            T+T   LS+T+ E      VIVP+  +N + ++ +    E      E I  YS F  E 
Sbjct: 144 GTLTVGLLSQTYLECVQAQAVIVPIVPFNQQNKKMII--TEDSLPSLEAILNYSIFNREN 201

Query: 121 EVMTQFMKIPGDSGTLVIIFNLKLMDNGEPELDIISNPRDIQMAETSPE--------GTK 172
           +++ QF  IPG  GT V+I+N++   NG+ ELD  ++  DI +++   E           
Sbjct: 202 DLLAQFDAIPGKKGTRVLIWNIRRNKNGKSELDFDTDQYDILVSDFDTEEKMTGGVTSEL 261

Query: 173 PERR-SFRAYAAVLYIDPRMRIFIHGHKVQTKRLSCCL-------YKP 212
           PE   S RA+  +LY+ PRM+IF+   KV T+ ++  L       YKP
Sbjct: 262 PETEYSLRAFCGILYMKPRMKIFLRQKKVTTQMIAKSLANVEYDTYKP 309



 Score =  101 bits (251), Expect = 4e-21
 Identities = 119/473 (25%), Positives = 189/473 (39%), Gaps = 80/473 (16%)

Query: 302 KELNFVFGVNIEHRDLDGMFIYNCSRLIKMYEKVGPQLEGGMACG-GVVGVVDVPYLVLE 360
           K++   FG + ++ +  G+ +Y+ +RLIK +EKVG Q++     G GV+GV++  +L  +
Sbjct: 314 KQVRITFGFSCKNSNQFGIMMYHNNRLIKSFEKVGCQVKPTRGEGVGVIGVIECNFL--K 371

Query: 361 PTHNKQDFADAKEYRHLLRAMGEHLAQYWKDIAIAQRGIIKFWDEFGYLSANWNQPPSSE 420
           P +NKQDF   KEYR  + A+ + L  YWK+            D F             E
Sbjct: 372 PAYNKQDFEYTKEYRLTINALAQKLNAYWKEKTSQ--------DNF-------------E 410

Query: 421 LRYKRRRAMEIP--TTIQCDLCLKWRTLPFQLSSVEKDYPDTWVCSMNPDPEQDRCEASE 478
                R   ++P  T +QCD CLKWR LP ++       P  W C  N  P+  RC   E
Sbjct: 411 TSTVARPIPKVPDQTWVQCDECLKWRKLPGKID--PSMLPARWFCYYNSHPKYRRCSVPE 468

Query: 479 QK----QKVPLGTFRKDMKTQEEKQKQLTEKIRQQQEKLEALQKTTPIRSQADL--KKLP 532
           ++    + + L   +K  +T EEK+K   E   +  +      K   ++  A L  K + 
Sbjct: 469 EQELTDEDLCLSKAKKQEQTVEEKKKMPME--NENHQVFSNPPKILTVQEMAGLNNKTIG 526

Query: 533 LEVTTRPSTEEPVRRPQRPRSPPLPAVIRNAPSRPPSLPTPRPASQPRKAPVISSTPKLP 592
            E    PS               LP+      SR PSL       +P  + V+  + K  
Sbjct: 527 YEGIHSPSV--------------LPS--GGEESRSPSLQL-----KPLDSSVLQFSSKYK 565

Query: 593 ALAAREEASTSRLLQPPEAPRKPANTLVKTASRPAPLVQQLSPSLLPNSKSPREVPSPKV 652
            +   E     R LQ          T     S PAP  +  +P   P  ++  +  S + 
Sbjct: 566 WILGEEPVEKRRRLQ------NEMTTPSLDYSMPAPYRRVEAPVAYPEGENSHDKSSSER 619

Query: 653 IKTPVV--------KKTESPIKLSPATPSRK--RSVAVSDEEEVEEEAERRKERCKRGRF 702
              P +        K T    ++S   P  K  R  ++  EE  ++      E   RG  
Sbjct: 620 STPPYLFPEYPEASKNTGQNREVSILYPGAKDQRQGSLLPEELEDQMPRLVAEESNRGST 679

Query: 703 VVKEEKKDSNELSDSAGEEDSADLKRAQKDKGLHVE-VRVNREWYTGRVTAVE 754
            + +E+ +        G      + +  +D G  ++ +  NRE    R  AVE
Sbjct: 680 TINKEEVNKGPFVAVVG------VAKGVRDSGAPIQLIPFNREELAERRKAVE 726


>gi|145553971 zinc finger, CW type with coiled-coil domain 2 isoform
           b [Homo sapiens]
          Length = 900

 Score =  129 bits (325), Expect = 1e-29
 Identities = 84/228 (36%), Positives = 122/228 (53%), Gaps = 19/228 (8%)

Query: 2   LCFLDDGAGMDPSDAASVIQFGKSAKRTPEST-QIGQYGNGLKSGSMRIGKDFILFTKKE 60
           L F DDG GM P     ++ FG + K   +S   IG +GNG KSGSMR+GKD ++FTK  
Sbjct: 84  LTFTDDGCGMTPHKLHRMLSFGFTDKVIKKSQCPIGVFGNGFKSGSMRLGKDALVFTKNG 143

Query: 61  DTMTCLFLSRTFHEEEGIDEVIVPLPTWNARTREPVTDNVEKFAIETELIYKYSPFRTEE 120
            T+T   LS+T+ E      VIVP+  +N + ++ +    E      E I  YS F  E 
Sbjct: 144 GTLTVGLLSQTYLECVQAQAVIVPIVPFNQQNKKMII--TEDSLPSLEAILNYSIFNREN 201

Query: 121 EVMTQFMKIPGDSGTLVIIFNLKLMDNGEPELDIISNPRDIQMAETSPE--------GTK 172
           +++ QF  IPG  GT V+I+N++   NG+ ELD  ++  DI +++   E           
Sbjct: 202 DLLAQFDAIPGKKGTRVLIWNIRRNKNGKSELDFDTDQYDILVSDFDTEEKMTGGVTSEL 261

Query: 173 PERR-SFRAYAAVLYIDPRMRIFIHGHKVQTKRLSCCL-------YKP 212
           PE   S RA+  +LY+ PRM+IF+   KV T+ ++  L       YKP
Sbjct: 262 PETEYSLRAFCGILYMKPRMKIFLRQKKVTTQMIAKSLANVEYDTYKP 309



 Score =  101 bits (251), Expect = 4e-21
 Identities = 119/473 (25%), Positives = 189/473 (39%), Gaps = 80/473 (16%)

Query: 302 KELNFVFGVNIEHRDLDGMFIYNCSRLIKMYEKVGPQLEGGMACG-GVVGVVDVPYLVLE 360
           K++   FG + ++ +  G+ +Y+ +RLIK +EKVG Q++     G GV+GV++  +L  +
Sbjct: 314 KQVRITFGFSCKNSNQFGIMMYHNNRLIKSFEKVGCQVKPTRGEGVGVIGVIECNFL--K 371

Query: 361 PTHNKQDFADAKEYRHLLRAMGEHLAQYWKDIAIAQRGIIKFWDEFGYLSANWNQPPSSE 420
           P +NKQDF   KEYR  + A+ + L  YWK+            D F             E
Sbjct: 372 PAYNKQDFEYTKEYRLTINALAQKLNAYWKEKTSQ--------DNF-------------E 410

Query: 421 LRYKRRRAMEIP--TTIQCDLCLKWRTLPFQLSSVEKDYPDTWVCSMNPDPEQDRCEASE 478
                R   ++P  T +QCD CLKWR LP ++       P  W C  N  P+  RC   E
Sbjct: 411 TSTVARPIPKVPDQTWVQCDECLKWRKLPGKID--PSMLPARWFCYYNSHPKYRRCSVPE 468

Query: 479 QK----QKVPLGTFRKDMKTQEEKQKQLTEKIRQQQEKLEALQKTTPIRSQADL--KKLP 532
           ++    + + L   +K  +T EEK+K   E   +  +      K   ++  A L  K + 
Sbjct: 469 EQELTDEDLCLSKAKKQEQTVEEKKKMPME--NENHQVFSNPPKILTVQEMAGLNNKTIG 526

Query: 533 LEVTTRPSTEEPVRRPQRPRSPPLPAVIRNAPSRPPSLPTPRPASQPRKAPVISSTPKLP 592
            E    PS               LP+      SR PSL       +P  + V+  + K  
Sbjct: 527 YEGIHSPSV--------------LPS--GGEESRSPSLQL-----KPLDSSVLQFSSKYK 565

Query: 593 ALAAREEASTSRLLQPPEAPRKPANTLVKTASRPAPLVQQLSPSLLPNSKSPREVPSPKV 652
            +   E     R LQ          T     S PAP  +  +P   P  ++  +  S + 
Sbjct: 566 WILGEEPVEKRRRLQ------NEMTTPSLDYSMPAPYRRVEAPVAYPEGENSHDKSSSER 619

Query: 653 IKTPVV--------KKTESPIKLSPATPSRK--RSVAVSDEEEVEEEAERRKERCKRGRF 702
              P +        K T    ++S   P  K  R  ++  EE  ++      E   RG  
Sbjct: 620 STPPYLFPEYPEASKNTGQNREVSILYPGAKDQRQGSLLPEELEDQMPRLVAEESNRGST 679

Query: 703 VVKEEKKDSNELSDSAGEEDSADLKRAQKDKGLHVE-VRVNREWYTGRVTAVE 754
            + +E+ +        G      + +  +D G  ++ +  NRE    R  AVE
Sbjct: 680 TINKEEVNKGPFVAVVG------VAKGVRDSGAPIQLIPFNREELAERRKAVE 726


>gi|28872812 MORC family CW-type zinc finger 3 [Homo sapiens]
          Length = 939

 Score =  121 bits (304), Expect = 3e-27
 Identities = 156/678 (23%), Positives = 283/678 (41%), Gaps = 89/678 (13%)

Query: 302 KELNFVFGVNIEHRDLDGMFIYNCSRLIKMYEKVGPQLEGGMACGGVVGVVDVPYLVLEP 361
           K +   FG N  ++D  G+ +Y+ +RLIK YEKVG QL       GVVG+++  +  L+P
Sbjct: 297 KTVRITFGFNCRNKDHYGIMMYHRNRLIKAYEKVGCQLRANNMGVGVVGIIECNF--LKP 354

Query: 362 THNKQDFADAKEYRHLLRAMGEHLAQYWKDIAIAQRGIIKFWDEFGYLSANWNQPPSSEL 421
           THNKQDF    EYR  + A+GE L  YW ++ + +               N   P +  +
Sbjct: 355 THNKQDFDYTNEYRLTITALGEKLNDYWNEMKVKK---------------NTEYPLNLPV 399

Query: 422 RYKRRRAMEIPTTIQCDLCLKWRTLPFQLSSVEKDYPDTWVCSMNPDPEQDRCEASEQKQ 481
              ++R  +  T +QCD CLKWR LP  +  +    P+ W CS NPDP+   CE  E+ +
Sbjct: 400 EDIQKRPDQ--TWVQCDACLKWRKLPDGMDQL----PEKWYCSNNPDPQFRNCEVPEEPE 453

Query: 482 KVPL--GTFRKDMKTQEEKQKQLTEKIRQQQEKLEALQKTTPIRSQADLKKLPLEVTTRP 539
              L   T+ K  K             +  +EK    Q     R  A+L   P  ++T P
Sbjct: 454 DEDLVHPTYEKTYK-------------KTNKEKFRIRQPEMIPRINAELLFRPTALST-P 499

Query: 540 STEEPVRR-PQRPRSPPLPAVIRNAPSRPPSLPTPRPASQPRKAPVISSTPKLPA----L 594
           S   P    P+R  S    +      +     P   P S   K  + + +  L A    L
Sbjct: 500 SFSSPKESVPRRHLSEGTNSYATRLLNNHQVPPQSEPESNSLKRRLSTRSSILNAKNRRL 559

Query: 595 AAREEASTSR---------LLQPPEAPRKPANTLVKTASRPAPLVQ-QLSPSLLPNSKSP 644
           +++ E S  +         +L+    P+   +  +   S  + + Q  +    + +S+  
Sbjct: 560 SSQFENSVYKGDDDDEDVIILEENSTPKPAVDHDIDMKSEQSHVEQGGVQVEFVGDSEPC 619

Query: 645 REVPSPKVIKTPVVKKTESPIKLSPATPSRKRSVAVSDEEEVEEEAERRKERCKRGRFVV 704
            +  S     +   +        + AT +   S+ V  EE VE+E + R +       V 
Sbjct: 620 GQTGSTSTSSSRCDQGN------TAATQTEVPSLVVKKEETVEDEIDVRNDAVILPSCVE 673

Query: 705 KEEK-KDSNELSDSAGEEDSADLKRAQKDKGLHVEVRVNRE----WYTGRVTAVEVGKHV 759
            E K  ++ E +D + ++    L+  +    L  E + N +     +T ++  ++  + +
Sbjct: 674 AEAKIHETQETTDKSADDAGCQLQELRNQLLLVTEEKENYKRQCHMFTDQIKVLQ--QRI 731

Query: 760 VRWKVKFDYVPTDTTPRDRWVEKGSEDVRLM-----KPPSPEHQSLDTQQEGGEEEVGPV 814
           +    K  YV  +T  +       ++ V L+     K  SP+H  + +Q +   EE+  +
Sbjct: 732 LEMNDK--YVKKETCHQ----STETDAVFLLESINGKSESPDH--MVSQYQQALEEIERL 783

Query: 815 AQQAIAVAEPSTSECLRIEPDTTALSTNHETIDLLVQILRNCLRYFLPPSFPISKKQLSA 874
            +Q  A+ +   +EC +   +  + S   E    L  + R   +  +      S+ +L  
Sbjct: 784 KKQCSAL-QHVKAECSQCS-NNESKSEMDEMAVQLDDVFRQLDKCSIERDQYKSEVELLE 841

Query: 875 MNSDELISFPLKEYFKQYEVGLQNLCNSYQSRADSRAKASEESLRTSERKLRETEEKLQK 934
           M   +     ++   ++ +  ++ L ++ Q  A   + +S  ++  S   +     KL+ 
Sbjct: 842 MEKSQ-----IRSQCEELKTEVEQLKSTNQQTATDVSTSS--NIEESVNHMDGESLKLRS 894

Query: 935 LRTNIVALLQKVQEDIDI 952
           LR N+  LL  +  D+D+
Sbjct: 895 LRVNVGQLLAMIVPDLDL 912



 Score =  119 bits (298), Expect = 1e-26
 Identities = 82/240 (34%), Positives = 127/240 (52%), Gaps = 27/240 (11%)

Query: 2   LCFLDDGAGMDPSDAASVIQFGKSAKRTPES-TQIGQYGNGLKSGSMRIGKDFILFTKKE 60
           L F D+G GM       ++ FG S K T      +G YGNG KSGSMR+GKD I+FTK  
Sbjct: 63  LTFTDNGNGMTSDKLHKMLSFGFSDKVTMNGHVPVGLYGNGFKSGSMRLGKDAIVFTKNG 122

Query: 61  DTMTCLFLSRTFHEEEGIDEVIVPLPTWNARTREPVTDNVEKFAIETELIYKYSPFRTEE 120
           ++M+   LS+T+ E    + V+VP+  +N + R+ +  N+ +       I ++S F TE+
Sbjct: 123 ESMSVGLLSQTYLEVIKAEHVVVPIVAFN-KHRQMI--NLAESKASLAAILEHSLFSTEQ 179

Query: 121 EVMTQFMKIPGDSGTLVIIFNLKLMDNGEPELDIISNPRDIQMAE-----TSPEGTKPER 175
           +++ +   I G  GT +II+NL+   N   E D   +  DI++ E     T  +G K + 
Sbjct: 180 KLLAELDAIIGKKGTRIIIWNLRSYKNA-TEFDFEKDKYDIRIPEDLDEITGKKGYKKQE 238

Query: 176 R----------SFRAYAAVLYIDPRMRIFIHGHKVQTKRLSCCL-------YKPRMYKYT 218
           R          S RAY ++LY+ PRM+I + G KV+T+ +S  L       Y+P+    T
Sbjct: 239 RMDQIAPESDYSLRAYCSILYLKPRMQIILRGQKVKTQLVSKSLAYIERDVYRPKFLSKT 298


>gi|110349719 titin isoform N2-A [Homo sapiens]
          Length = 33423

 Score = 63.9 bits (154), Expect = 7e-10
 Identities = 89/374 (23%), Positives = 151/374 (40%), Gaps = 44/374 (11%)

Query: 488   FRKDMKTQ-EEKQKQLTEKIRQQQEKLEALQKTTPIRSQADLKKLPLEVTTRPSTEE--P 544
             F +++ T  EE   +  E+   ++E+    ++  P+       K+P EV  +P  EE  P
Sbjct: 9910  FEEEVVTHVEEYLVEEEEEYIHEEEEFITEEEVVPVIPV----KVP-EVPRKPVPEEKKP 9964

Query: 545   VRRPQRPRSPP--LPAVIRNAPSRPPSLPTPRPASQPRKAPVISSTP----KLPALAARE 598
             V  P++  +PP  +P V +    + P L   +    P K P +   P    K+P    ++
Sbjct: 9965  VPVPKKKEAPPAKVPEVPKKPEEKVPVLIPKKEKPPPAKVPEVPKKPVPEEKVPVPVPKK 10024

Query: 599   -EASTSRLLQPPEAPRKPANT------LVKTASRPAPLVQQLSPSLLPNSKSPREVPSPK 651
              EA  +++   PE P+KP           K    P   V ++   L+P  K P  VP   
Sbjct: 10025 VEAPPAKV---PEVPKKPVPEKKVPVPAPKKVEAPPAKVPEVPKKLIPEEKKPTPVPKKV 10081

Query: 652   VIKTPVVKKTESPIKLSPATPSRKRSV----AVSDEEEVEEEAE---RRKERCKRGRFVV 704
                 P V K   P+ +  A P  +  +     V +EE + EE E     +E       V+
Sbjct: 10082 EAPPPKVPKKREPVPVPVALPQEEEVLFEEEIVPEEEVLPEEEEVLPEEEEVLPEEEEVL 10141

Query: 705   KEEKKDSNELSDSAGEEDSA-DLKRAQKDKGLHVEVRVNREWYTGRVTAVEVGKHVVRWK 763
              EE++   E  +   EE+   + +    ++ +  EV+             E+ K V   K
Sbjct: 10142 PEEEEIPPEEEEVPPEEEYVPEEEEFVPEEEVLPEVKPK---VPVPAPVPEIKKKVTEKK 10198

Query: 764   V---KFDYVPTDTTPRDRWVEKGSEDVRLMKPPSPEHQSLDTQQEGGEEEVGPVAQQAIA 820
             V   K +  P    P    V K  E+ R++ P   E   ++  +E  EE   P++++ I 
Sbjct: 10199 VVIPKKEEAPPAKVPE---VPKKVEEKRIILPKEEEVLPVEVTEEPEEE---PISEEEIP 10252

Query: 821   VAEPSTSECLRIEP 834
                PS  E   + P
Sbjct: 10253 EEPPSIEEVEEVAP 10266



 Score = 52.8 bits (125), Expect = 2e-06
 Identities = 60/252 (23%), Positives = 100/252 (39%), Gaps = 33/252 (13%)

Query: 470   EQDRCEASEQKQKVPLGTFRKDMKTQEEKQKQLTEKIRQQQEKLEALQKTTPIRSQ---- 525
             EQ R E   + +KV      + ++  E ++ ++ EK +   +  E  +K  P +      
Sbjct: 10405 EQHRVEEEHRVEKV-----HRVIEVFEAEEVEVFEKPKAPPKGPEISEKIIPPKKPPTKV 10459

Query: 526   ADLKKLPLEVTTRPS---TEEPVRRPQRPRSPP--LPAV-----------IRNAPSRPPS 569
                K+ P +V   P     EE VR P+ PR PP  +P V           +   P++ P 
Sbjct: 10460 VPRKEPPAKVPEVPKKIVVEEKVRVPEEPRVPPTKVPEVLPPKEVVPEKKVPVPPAKKPE 10519

Query: 570   LPTPRPASQPRKAPVISSTPKLPALAAREEASTSRLLQPPEA---PRKPANTLVKTASRP 626
              P P+    P++       P  P    + E   +++ + P+A    +K    +      P
Sbjct: 10520 APPPKVPEAPKEVVPEKKVPVPP--PKKPEVPPTKVPEVPKAAVPEKKVPEAIPPKPESP 10577

Query: 627   APLVQQLSPSLLPNSKSPREVP-SPKV--IKTPVVKKTESPIKLSPATPSRKRSVAVSDE 683
              P V +    ++P  K P   P  P+V  +K P   K   P K  P  P +K  V  +  
Sbjct: 10578 PPEVPEAPKEVVPEKKVPAAPPKKPEVTPVKVPEAPKEVVPEKKVPVPPPKKPEVPPTKV 10637

Query: 684   EEVEEEAERRKE 695
              EV + A   K+
Sbjct: 10638 PEVPKVAVPEKK 10649



 Score = 52.0 bits (123), Expect = 3e-06
 Identities = 58/243 (23%), Positives = 93/243 (38%), Gaps = 35/243 (14%)

Query: 454   EKDYPDTWVCSMNPDPEQDRCEASEQKQKVPLGTFRKDMKTQEEKQKQLTEKIRQQQEKL 513
             EK  P+    ++ P PE    E  E+ ++V L          EE   ++ E    + E  
Sbjct: 10647 EKKVPE----AIPPKPESPPPEVFEEPEEVAL----------EEPPAEVVE----EPEPA 10688

Query: 514   EALQKTTPIRSQADLKKLPLEVTTRPSTEEPVRRPQRPRS----PPLPAVIRNAPSRPPS 569
                Q T P +     KK P  V  +P    PV+ P+ P+       +P V+   P  PP+
Sbjct: 10689 APPQVTVPPKKPVPEKKAPAVVAKKPELP-PVKVPEVPKEVVPEKKVPLVVPKKPEAPPA 10747

Query: 570   -LPTPRPASQPRKAPVISSTPKLPALAAREEASTSRLLQPPEAPRKPANTLVKTASRPAP 628
              +P       P K   +   P++P       A    + + P    KPA  + + A  P P
Sbjct: 10748 KVPEVPKEVVPEKKVAVPKKPEVPP------AKVPEVPKKPVLEEKPAVPVPERAESPPP 10801

Query: 629   LVQQLSPSLLPNSKSPREVPSPKVIKTPVVKKTESPIKLSPATPSRKRSVAVSDEEEVEE 688
              V +      P   +P E  +P+  K   V + E P    PA P   + +    +  V +
Sbjct: 10802 EVYEE-----PEEIAPEEEIAPEEEKPVPVAEEEEPEVPPPAVPEEPKKIIPEKKVPVIK 10856

Query: 689   EAE 691
             + E
Sbjct: 10857 KPE 10859



 Score = 46.2 bits (108), Expect = 1e-04
 Identities = 107/526 (20%), Positives = 194/526 (36%), Gaps = 67/526 (12%)

Query: 477  SEQKQKVPLGTFRKDMKTQEEKQKQLTEKIRQQQEKLEALQKTTPI---------RSQAD 527
            +E++  V +   +K++ T+E+    +++++    +  E  +K  P          + +  
Sbjct: 9253 TEEEVSVTVPEVQKEIVTEEKIHVAISKRVEPPPKVPELPEKPAPEEVAPVPIPKKVEPP 9312

Query: 528  LKKLPLEVTTRPSTEE----------PVRRPQRPRSPPLPAVIRNAPSRPPSLPTPRPAS 577
              K+P EV  +P  EE          P   P+ P  P  P      P          PA 
Sbjct: 9313 APKVP-EVPKKPVPEEKKPVPVPKKEPAAPPKVPEVPKKPVPEEKIPVPVAKKKEAPPAK 9371

Query: 578  QPRKAPVISSTPKLPALAAREEASTSRLLQPPEAPRKPANTLVKTASR------PAPLVQ 631
             P     + +  K+  +  REE+    +   PE P+K      K   R      P P V 
Sbjct: 9372 VPEVQKGVVTEEKITIVTQREESPPPAV---PEIPKKKVPEERKPVPRKEEEVPPPPKVP 9428

Query: 632  QLSPSLLPNSKSPREVPSPKVIKTP---VVKKT-------ESPIKLSPATPSRKRSVAVS 681
             L    +P  K    VP  K    P   V KKT        +  KLS A P R       
Sbjct: 9429 ALPKKPVPEEKVAVPVPVAKKAPPPRAEVSKKTVVEEKRFVAEEKLSFAVPQRVE--VTR 9486

Query: 682  DEEEVEEEAERRKERCKRGRFVVKEEKKDSNELSDSAGEEDSADLKRAQKDKGLH-VEVR 740
             E   EEE    +E       V +EE+++  E ++    E   + +    ++ LH +  R
Sbjct: 9487 HEVSAEEEWSYSEEEEGVSISVYREEEREEEEEAEVTEYEVMEEPEEYVVEEKLHIISKR 9546

Query: 741  VNREWYTGRVTAVEVGKHVVRWKV--KFDYVPTDTTPRDRWVEKGSEDVRLMKPPSPEHQ 798
            V  E     VT  +  K V++ K+  K +  P    P      K     + +  P P+ +
Sbjct: 9547 VEAE--PAEVTERQEKKIVLKPKIPAKIEEPPPAKVPE---APKKIVPEKKVPAPVPKKE 9601

Query: 799  SLDTQQEGGEEEVGPVAQQAIAVAEPSTSECLRIEPDTTALSTNHETIDLLVQILRNCLR 858
             +   +   EE   PV ++ +    P   +    EP    ++  H  I    ++L    +
Sbjct: 9602 KVPPPKV-PEEPKKPVPEKKV---PPKVIK--MEEPLPAKVTERHMQITQEEKVLVAVTK 9655

Query: 859  YFLPPSFPISKKQLSAMNSDELISF-PLKEYFKQYEVGLQNLCNSYQSRADSRAKASEES 917
               PP   + ++   A+  ++++   P +E     +V        ++ R     K S E+
Sbjct: 9656 KEAPPKARVPEEPKRAVPEEKVLKLKPKREEEPPAKV------TEFRKRVVKEEKVSIEA 9709

Query: 918  LRTSERKLRETEEKLQKLRTNIVALLQKVQEDIDINTDDELDAYIE 963
             +   + ++E     +K R   +      +E + +  ++E + Y E
Sbjct: 9710 PKREPQPIKEVTIMEEKERAYTLE-----EEAVSVQREEEYEEYEE 9750



 Score = 45.4 bits (106), Expect = 3e-04
 Identities = 47/212 (22%), Positives = 81/212 (38%), Gaps = 39/212 (18%)

Query: 496  EEKQKQLTEKIRQQQEKLEALQKTTPIRSQADLKKLPLEVTTRPSTEEPVRRPQRPRSPP 555
            EE +++  E+  + +E +   +K  P++               P  EEPV  P +P++PP
Sbjct: 9769 EEYEEREYERYEEHEEYITEPEKPIPVK---------------PVPEEPV--PTKPKAPP 9811

Query: 556  LPAVIRNAPSRPPSLPTPRPASQPRKAPVISSTPKLPALAAREEASTSRLLQPPEAPRKP 615
               + +  P     +P P+    P         P+ P     E+   S   +  E   +P
Sbjct: 9812 AKVLKKAVPEEKVPVPIPKKLKPPPP-----KVPEEPKKVFEEKIRISITKREKEQVTEP 9866

Query: 616  ANTLVKTASRPAPLVQQLSPSLLPNSKSPREVPSPKVIKTPVVKKTESPIKLSPATPSRK 675
            A    K   +P  +V +             +VP P+    P V+  E P +L P   + +
Sbjct: 9867 A---AKVPMKPKRVVAE------------EKVPVPRKEVAPPVRVPEVPKELEPEEVAFE 9911

Query: 676  RSVAVSDEEEVEEEAERRKERCKRGRFVVKEE 707
              V    EE + EE E      +   F+ +EE
Sbjct: 9912 EEVVTHVEEYLVEEEEEYIH--EEEEFITEEE 9941



 Score = 44.7 bits (104), Expect = 4e-04
 Identities = 53/237 (22%), Positives = 91/237 (38%), Gaps = 17/237 (7%)

Query: 467   PDPEQ--DRCEASEQKQKVPLGTFRKDMKTQEEKQKQLTEKIRQQQEKLEALQKTTPIRS 524
             P+PE+  ++ +   +    P    ++D+K +  + K + +K   ++ ++    + TP++ 
Sbjct: 10866 PEPEKVIEKPKLKPRPPPPPPAPPKEDVKEKIFQLKAIPKKKVPEKPQVPEKVELTPLKV 10925

Query: 525   QADLKKLPLEVTTRPSTEEPVRRPQRPRSPPLPAVIRNAPSRPPSLPTPRPASQPRKAPV 584
                 KK+   +        P R+P+      L +V+R  P        P+   + +K  V
Sbjct: 10926 PGGEKKVRKLL--------PERKPEPKEEVVLKSVLRKRPEEEEPKVEPKKLEKVKKPAV 10977

Query: 585   ISSTPKLPALAAREEASTSRLLQPPEAPR----KPANTLVKTASRPAPLVQQLSPSLLPN 640
                 P  P         T R  + PE  +    KPA  L   A  P P  +    ++ P 
Sbjct: 10978 PEPPPPKPVEEVEVPTVTKRERKIPEPTKVPEIKPAIPL--PAPEPKPKPEAEVKTIKPP 11035

Query: 641   SKSPREVPSPKVIKTPVV-KKTESPIKLSPATPSRKRSVAVSDEEEVEEEAERRKER 696
                P   P    +  PVV KK E+      A   +     V  +     EAERRK R
Sbjct: 11036 PVEPEPTPIAAPVTVPVVGKKAEAKAPKEEAAKPKGPIKGVPKKTPSPIEAERRKLR 11092



 Score = 43.1 bits (100), Expect = 0.001
 Identities = 45/174 (25%), Positives = 69/174 (39%), Gaps = 11/174 (6%)

Query: 529   KKLPLEVTTRPSTEEPVRRPQRPRSPPLPAVIRNAPSRPPSLPTPRPASQPRKAPVISST 588
             KK+P     +P    PV+ P+ P+   +P   +  P  PP  P   P   P    V    
Sbjct: 10592 KKVPAAPPKKPEVT-PVKVPEAPKEV-VPE--KKVPVPPPKKPEVPPTKVPEVPKVAVPE 10647

Query: 589   PKLP-ALAAREEASTSRLLQPPE--APRKPANTLVKTASRPAPLVQQLSPSL-LPNSKSP 644
              K+P A+  + E+    + + PE  A  +P   +V+     AP    + P   +P  K+P
Sbjct: 10648 KKVPEAIPPKPESPPPEVFEEPEEVALEEPPAEVVEEPEPAAPPQVTVPPKKPVPEKKAP 10707

Query: 645   REV---PSPKVIKTPVVKKTESPIKLSPATPSRKRSVAVSDEEEVEEEAERRKE 695
               V   P    +K P V K   P K  P    +K     +   EV +E    K+
Sbjct: 10708 AVVAKKPELPPVKVPEVPKEVVPEKKVPLVVPKKPEAPPAKVPEVPKEVVPEKK 10761



 Score = 41.2 bits (95), Expect = 0.005
 Identities = 42/160 (26%), Positives = 68/160 (42%), Gaps = 34/160 (21%)

Query: 478   EQKQKVPLGTFRKDMKTQ--------EEKQKQLTEKIRQQQEKLEALQKTTPIRSQADLK 529
             E K KVP+     ++K +         +K++    K+ +  +K+E  +   P   +    
Sbjct: 10176 EVKPKVPVPAPVPEIKKKVTEKKVVIPKKEEAPPAKVPEVPKKVEEKRIILPKEEEV--- 10232

Query: 530   KLPLEVTTRPSTEEPVRRPQRPRSPP------------LPAVIRNAPSRPPSLPTPRP-- 575
              LP+EVT  P  EEP+   + P  PP            +P VI+ A    P  PTP P  
Sbjct: 10233 -LPVEVTEEPE-EEPISEEEIPEEPPSIEEVEEVAPPRVPEVIKKA---VPEAPTPVPKK 10287

Query: 576   -ASQPRKAPVISSTPKLPALAAREEASTSRLLQPPEAPRK 614
               + P K        K+P    ++EA  +++   PE P+K
Sbjct: 10288 VEAPPAKVSKKIPEEKVPVPVQKKEAPPAKV---PEVPKK 10324



 Score = 40.0 bits (92), Expect = 0.011
 Identities = 73/338 (21%), Positives = 117/338 (34%), Gaps = 89/338 (26%)

Query: 469   PEQDRCEASEQKQKVPLGTFRKDMKTQEEKQKQLTEKIRQQQEKLEALQKTTPIRSQADL 528
             PE  R    E+K+ VP+       K +E    ++ E  ++ +EK+  L    P + +   
Sbjct: 9951  PEVPRKPVPEEKKPVPVP------KKKEAPPAKVPEVPKKPEEKVPVL---IPKKEKPPP 10001

Query: 529   KKLPLEVTTRPSTEE-------------PVRRPQRPRSP--------PLPAVIRNAPSRP 567
              K+P EV  +P  EE             P + P+ P+ P        P P  +   P++ 
Sbjct: 10002 AKVP-EVPKKPVPEEKVPVPVPKKVEAPPAKVPEVPKKPVPEKKVPVPAPKKVEAPPAKV 10060

Query: 568   PSLPTP------RPASQPRKAPVISSTPKLP----------ALAAREEASTSRLLQPPEA 611
             P +P        +P   P+K  V +  PK+P          AL   EE      + P E 
Sbjct: 10061 PEVPKKLIPEEKKPTPVPKK--VEAPPPKVPKKREPVPVPVALPQEEEVLFEEEIVPEEE 10118

Query: 612   PRKPANTLVKTASRPAPLVQQLSPS-----------------------------LLPNSK 642
                    ++       P  +++ P                              +LP  K
Sbjct: 10119 VLPEEEEVLPEEEEVLPEEEEVLPEEEEIPPEEEEVPPEEEYVPEEEEFVPEEEVLPEVK 10178

Query: 643   SPREVPSP------KVIKTPVV--KKTESPIKLSPATPSR---KRSVAVSDEEEVEEEAE 691
                 VP+P      KV +  VV  KK E+P    P  P +   KR +   +EE +  E  
Sbjct: 10179 PKVPVPAPVPEIKKKVTEKKVVIPKKEEAPPAKVPEVPKKVEEKRIILPKEEEVLPVEVT 10238

Query: 692   RRKERCKRGRFVVKEEKKDSNELSDSAGEEDSADLKRA 729
                E        + EE     E+ + A       +K+A
Sbjct: 10239 EEPEEEPISEEEIPEEPPSIEEVEEVAPPRVPEVIKKA 10276



 Score = 39.3 bits (90), Expect = 0.018
 Identities = 55/228 (24%), Positives = 87/228 (38%), Gaps = 41/228 (17%)

Query: 499  QKQLTEKIRQQQEKLEALQKTTPIRSQADLKKL--PLEVTTRPSTEEPVRRPQRPRSPPL 556
            QK++ E+  +++   +  +K  P   +   K +   +E T+R   EE V+  + P     
Sbjct: 9153 QKEVYEESHERKVPAKVPEKKAPPPPKVIKKPVIEKIEKTSRRMEEEKVQVTKVPEVSK- 9211

Query: 557  PAVIRNAPSRPPS----LPTPRPASQPRKAPVISSTPKLPALAAREEAST---------- 602
              ++   PSR P     +    PA   +K  VIS      A    EE S           
Sbjct: 9212 -KIVPQKPSRTPVQEEVIEVKVPAVHTKKM-VISEEKMFFASHTEEEVSVTVPEVQKEIV 9269

Query: 603  ---------SRLLQPP----EAPRKPANTLV------KTASRPAPLVQQLSPSLLPNSKS 643
                     S+ ++PP    E P KPA   V      K    PAP V ++    +P  K 
Sbjct: 9270 TEEKIHVAISKRVEPPPKVPELPEKPAPEEVAPVPIPKKVEPPAPKVPEVPKKPVPEEKK 9329

Query: 644  PREVPSPKVI---KTPVVKKTESPIKLSPATPSRKRSVAVSDEEEVEE 688
            P  VP  +     K P V K   P +  P   ++K+    +   EV++
Sbjct: 9330 PVPVPKKEPAAPPKVPEVPKKPVPEEKIPVPVAKKKEAPPAKVPEVQK 9377



 Score = 35.4 bits (80), Expect = 0.26
 Identities = 56/281 (19%), Positives = 107/281 (38%), Gaps = 27/281 (9%)

Query: 425   RRRAMEIPTTIQCDLCLKWRTLPFQLSSVEKDYPDTWVCSMNPDPEQDRCEASEQKQKVP 484
             +RR  E+P ++  +L    RT  + +SS +K               +    +S ++ K  
Sbjct: 32474 QRRDEEVPRSVFPELT---RTEAYAVSSFKKT-------------SEMEASSSVREVKSQ 32517

Query: 485   LGTFRKDMKTQEEKQKQLTEKIRQQQEKLEALQKTTPIRSQADLKKLPLEVTTRPSTEEP 544
             +   R+ + + E       +    +++ LE    T  I++    + L    +      E 
Sbjct: 32518 MTETRESLSSYEHSASAEMKSAALEEKSLEEKSTTRKIKTTLAARILTKPRSMTVYEGES 32577

Query: 545   VRRPQRPRSPPLPAVIRNAPSRPPSLPTPRPASQPRKAPVISSTPKLPALAAREEASTSR 604
              R        P+P V      +  S       +  +      ST ++ ++ A +E + S 
Sbjct: 32578 ARFSCDTDGEPVPTVTWLRKGQVLSTSARHQVTTTK----YKSTFEISSVQASDEGNYSV 32633

Query: 605   LLQPPEAPRKPANTLVKTASRPAPLVQQLSPSLL---PNSKSPREVPSPKVIKTPVVK-- 659
             +++  E  ++   TL    +R         P +    P  KSP  V SPK +K+P     
Sbjct: 32634 VVENSEGKQEAEFTLTIQKARVTEKAVTSPPRVKSPEPRVKSPEAVKSPKRVKSPEPSHP 32693

Query: 660   KTESPIKLSPATPSRKRSVAVSDEEEVEE--EAERRKERCK 698
             K  SP +  P    + + + VS   ++ +  +AE  KE  K
Sbjct: 32694 KAVSPTETKPTPTEKVQHLPVSAPPKITQFLKAEASKEIAK 32734



 Score = 34.3 bits (77), Expect = 0.58
 Identities = 38/180 (21%), Positives = 75/180 (41%), Gaps = 21/180 (11%)

Query: 454   EKDYPDTWVCSMNPDPEQDRCEASEQKQKVPLGTFRKDMKTQEEKQKQLTEKIRQQQEKL 513
             +++ P   V  +    E+ R    ++++ +P+     ++  + E++    E+I ++   +
Sbjct: 10204 KEEAPPAKVPEVPKKVEEKRIILPKEEEVLPV-----EVTEEPEEEPISEEEIPEEPPSI 10258

Query: 514   EALQKTTPIRSQADLKKLPLEVTTRPSTEEPVRRPQRPRSPPLPAVIRNAPSRPPSLPTP 573
             E +++  P R    +KK   E  T      PV  P++  +PP   V +  P     +P  
Sbjct: 10259 EEVEEVAPPRVPEVIKKAVPEAPT------PV--PKKVEAPP-AKVSKKIPEEKVPVPVQ 10309

Query: 574   RPASQPRKAP-VISSTPKLPALAAREEASTSRLLQPPEAPRKPANTLVKTASRPAPLVQQ 632
             +  + P K P V    P+   L  ++EA       PP   R      V  A R   +V++
Sbjct: 10310 KKEAPPAKVPEVPKKVPEKKVLVPKKEA------VPPAKGRTVLEEKVSVAFRQEVVVKE 10363


>gi|163965366 nascent polypeptide-associated complex alpha subunit
            isoform a [Homo sapiens]
          Length = 2078

 Score = 61.2 bits (147), Expect = 4e-09
 Identities = 46/149 (30%), Positives = 65/149 (43%), Gaps = 12/149 (8%)

Query: 532  PLEVTTRPSTEEPVRRPQRPRS---PPLPAVIRNAPSRPPSLPTPRPASQPRKAPVISST 588
            P+ +   P+T  P   P  P S   P LPAV   +P  PP+      +S P+KAP   + 
Sbjct: 1440 PVSLKKAPATSAPKGGPATPSSKGDPTLPAVTPPSPKEPPAPKQVATSSSPKKAPATPAP 1499

Query: 589  PKLPALAAREEASTSRLLQPPEAPRKPANTLVKTASRPAPLVQQLSPSLLPNSKSPREVP 648
               P L A   +S   +   P + R P        S+  P       +L+P + +   VP
Sbjct: 1500 MGAPTLPAVIPSSPKEVPATPSSRRDPIAPTATLLSKKTPATLAPKEALIPPAMT---VP 1556

Query: 649  SPKVIKTPVVKKTESPIKLSPATPSRKRS 677
            SPK  KTP +       K +PATPS K +
Sbjct: 1557 SPK--KTPAIPTP----KEAPATPSSKEA 1579



 Score = 57.4 bits (137), Expect = 6e-08
 Identities = 41/148 (27%), Positives = 68/148 (45%), Gaps = 7/148 (4%)

Query: 532  PLEVTTRPSTEEPVRRPQRPRSPPLPAVIRNAPSRPPSLPTPRPASQPRKAPVISSTPKL 591
            P +V T  S ++    P    +P LPAVI ++P   P+ P+ R       A ++S   K 
Sbjct: 1481 PKQVATSSSPKKAPATPAPMGAPTLPAVIPSSPKEVPATPSSRRDPIAPTATLLSK--KT 1538

Query: 592  PALAAREEASTSRLLQPPEAPRKPANTLVKTA-----SRPAPLVQQLSPSLLPNSKSPRE 646
            PA  A +EA     +  P   + PA    K A     S+ A     ++PS    + SP+E
Sbjct: 1539 PATLAPKEALIPPAMTVPSPKKTPAIPTPKEAPATPSSKEASSPPAVTPSTYKGAPSPKE 1598

Query: 647  VPSPKVIKTPVVKKTESPIKLSPATPSR 674
            +  P  + +P  K+  +P  ++P +P +
Sbjct: 1599 LLIPPAVTSPSPKEAPTPPAVTPPSPEK 1626



 Score = 51.6 bits (122), Expect = 4e-06
 Identities = 47/166 (28%), Positives = 70/166 (42%), Gaps = 26/166 (15%)

Query: 537  TRPSTEEPVRRPQRPRSPPLPAVIRNAPSRPPSLPTPR-------------PASQP---R 580
            T PS +     P     P  PAVI  +P + P+ P  R             PA  P   +
Sbjct: 1385 TPPSPKRGPAIPSPKGDPTSPAVIPLSPKKAPATPVTREGAATPSKGDLTPPAVTPVSLK 1444

Query: 581  KAPVISSTPKLPALAAREEASTSRLLQPPEAPRKPANTLVKTAS-------RPAPLVQQL 633
            KAP  S+    PA  + +   T   + PP     PA   V T+S        PAP+    
Sbjct: 1445 KAPATSAPKGGPATPSSKGDPTLPAVTPPSPKEPPAPKQVATSSSPKKAPATPAPMGAPT 1504

Query: 634  SPSLLPNSKSPREVP-SPKVIKTPVVKKTESPIKLSPATPSRKRSV 678
             P+++P+  SP+EVP +P   + P+        K +PAT + K ++
Sbjct: 1505 LPAVIPS--SPKEVPATPSSRRDPIAPTATLLSKKTPATLAPKEAL 1548



 Score = 50.4 bits (119), Expect = 8e-06
 Identities = 46/155 (29%), Positives = 59/155 (38%), Gaps = 18/155 (11%)

Query: 529  KKLPLEVTTRPSTEEPVRRPQRPRSPPLPAVIRNA-PSRPPSLPTPRPA-------SQPR 580
            K  P      P + + V  P  P+  P P+V+    P   P+ P P+ A       S P+
Sbjct: 862  KGAPTPSAVTPLSPKGVTLP--PKETPTPSVVNLPFPKEGPATPAPKQAPALSMTSSSPK 919

Query: 581  KAPVISSTPKLPALAAREEASTSRLLQPPEAPRKPANTLVKTASRPAPLVQQLSPSLLPN 640
            KA    +   +PA  + + A T     PP     PA    K A  P            P+
Sbjct: 920  KARATPAPKGIPASPSPKGAPTPPAATPPSPKGGPATPSPKWAPTPPAATP-------PS 972

Query: 641  SKSPREVPSPKVIKTPVVKKTESPIKLSPATPSRK 675
             K     PSPK   TP      SP K  PATPS K
Sbjct: 973  PKGGPATPSPKGAPTPPAATPPSP-KGGPATPSPK 1006



 Score = 48.5 bits (114), Expect = 3e-05
 Identities = 41/145 (28%), Positives = 56/145 (38%), Gaps = 8/145 (5%)

Query: 537  TRPSTEEPVRRPQRPRSPPLPAVIRNAPSRPPSLPTPRPASQPRKAPVISSTPKLPALAA 596
            T PS +  +  P    +P  PA    +P   P+ P P+ A  P  A   S    L A   
Sbjct: 1224 TPPSPKGGLATPSPKGAPTTPAATPPSPKGGPATPPPKGAPTPPAATPPSLKGGL-ATPP 1282

Query: 597  REEASTSRLLQPPEAPRKPANTLVKTASRPAPLVQQLSPSLLPNSKSPREVPSPKVIK-- 654
             + A    ++ PP     PA +  K A  P P     SP   P +  P+  P+P  +   
Sbjct: 1283 HKGAPNPAVVTPPSPKGGPATSPPKGAPTP-PAATPPSPKGSPGTPPPKGAPTPPAVTPP 1341

Query: 655  ----TPVVKKTESPIKLSPATPSRK 675
                TP +  T    K  P TPS K
Sbjct: 1342 SPKGTPTLPATTPSSKGGPTTPSSK 1366



 Score = 46.2 bits (108), Expect = 1e-04
 Identities = 46/167 (27%), Positives = 60/167 (35%), Gaps = 17/167 (10%)

Query: 519  TTPIRSQADLKKLPLEVTTRPSTEEPVRRPQRPRSPPLPAVIRNAPSRPPSLP------- 571
            T P  +    K  P   + + +   P   P  P+  P     + AP+ P + P       
Sbjct: 941  TPPAATPPSPKGGPATPSPKWAPTPPAATPPSPKGGPATPSPKGAPTPPAATPPSPKGGP 1000

Query: 572  -TPRPASQPRKAPVISSTPKLPALAA--REEASTSRLLQPPEAPRKPANTLVKTASRPAP 628
             TP P   P    V   +PK    A    + AST     PP     PA T +   +   P
Sbjct: 1001 ATPSPKGAPTPPAVTPPSPKGSPAATPFPKGASTPPAATPPSPKGSPAATPLPKGAPTTP 1060

Query: 629  LVQQLSPSLLPNSKSPREVPSPKVIKTPVVKKTESPIKLSPATPSRK 675
                   + LP+ K     PS K   TP      SP K  PATPS K
Sbjct: 1061 ------AATLPSPKGGPATPSLKGAPTPPAATPPSP-KGGPATPSPK 1100



 Score = 45.4 bits (106), Expect = 3e-04
 Identities = 43/147 (29%), Positives = 67/147 (45%), Gaps = 18/147 (12%)

Query: 536  TTRPSTEEPVRRPQRPRSPPLPAVIRNAPSRPPSLPTPR--PAS------QPRKAPVISS 587
            TT  S E P      P     PA+   +P R P++P+P+  P S       P+KAP    
Sbjct: 1361 TTPSSKEGPTPPAATPSHKGGPAMTPPSPKRGPAIPSPKGDPTSPAVIPLSPKKAPATPV 1420

Query: 588  TPKLPALAAREEASTSRLLQPPEAPRKPANTLVKTA-SRPAPLVQQLSPSLLPNSKSPRE 646
            T +  A  ++ +  T   + P    + PA +  K   + P+       P++ P   SP+E
Sbjct: 1421 TREGAATPSKGDL-TPPAVTPVSLKKAPATSAPKGGPATPSSKGDPTLPAVTP--PSPKE 1477

Query: 647  VPSPKVIKTPVVKKTESPIKLSPATPS 673
             P+PK + T     + SP K +PATP+
Sbjct: 1478 PPAPKQVAT-----SSSP-KKAPATPA 1498



 Score = 45.1 bits (105), Expect = 3e-04
 Identities = 39/157 (24%), Positives = 51/157 (32%), Gaps = 15/157 (9%)

Query: 519  TTPIRSQADLKKLPLEVTTRPSTEEPVRRPQRPRSPPLPAVIRNAPSRPPSLPTPRPASQ 578
            T P  +    K  P   + + +   P   P  P+  P         S PP+   P P   
Sbjct: 987  TPPAATPPSPKGGPATPSPKGAPTPPAVTPPSPKGSPAATPFPKGASTPPAATPPSPKGS 1046

Query: 579  PRKAPVISSTPKLPALAAREEASTSRLLQPPEAPRKPANTLVKTASRPAPLVQQLSPSLL 638
            P   P+    P  PA               P     PA   +K A  P P     SP   
Sbjct: 1047 PAATPLPKGAPTTPAATL------------PSPKGGPATPSLKGAPTP-PAATPPSPKGG 1093

Query: 639  PNSKSPREVPSPKVIKTPVVK--KTESPIKLSPATPS 673
            P + SP+  P P     P  K      P K +P TP+
Sbjct: 1094 PATPSPKGAPMPPAATPPSPKGGLATPPHKGAPTTPA 1130



 Score = 42.4 bits (98), Expect = 0.002
 Identities = 38/121 (31%), Positives = 51/121 (42%), Gaps = 13/121 (10%)

Query: 561 RNAPSRPPSLPTPRPASQPRKAPVISSTPKLPALAAREEASTS--RLLQPPEAPRKPAN- 617
           +++P+   S   P P   P  + V   +PK   L  +E  + S   L  P E P  PA  
Sbjct: 847 KDSPATTHSPTPPSPKGAPTPSAVTPLSPKGVTLPPKETPTPSVVNLPFPKEGPATPAPK 906

Query: 618 ---TLVKTASRPAPLVQQLSPSLLPNSKSPREVPSPKVIKTPVVKKTESPIKLSPATPSR 674
               L  T+S P       +P  +P S SP+  P+P     P      SP K  PATPS 
Sbjct: 907 QAPALSMTSSSPKKARATPAPKGIPASPSPKGAPTPPAATPP------SP-KGGPATPSP 959

Query: 675 K 675
           K
Sbjct: 960 K 960



 Score = 40.8 bits (94), Expect = 0.006
 Identities = 37/118 (31%), Positives = 53/118 (44%), Gaps = 14/118 (11%)

Query: 557  PAVIRNAPSRPPSLPTPRPASQPRKAPVISSTPKLPALAAREEASTSRLLQPPEAPRKPA 616
            PA+   +P + P++PTP+ A     +   SS P +     +   S   LL PP A   P+
Sbjct: 1551 PAMTVPSPKKTPAIPTPKEAPATPSSKEASSPPAVTPSTYKGAPSPKELLIPP-AVTSPS 1609

Query: 617  NTLVKTASRPAPLVQQLSPSLLPNSKSPREVP-SPKVIKTPVVKKTESPIKLSPATPS 673
                K A  P P V   SP   P + +P+  P SP V        T S +K SP +P+
Sbjct: 1610 ---PKEAPTP-PAVTPPSPEKGPATPAPKGTPTSPPV--------TPSSLKDSPTSPA 1655



 Score = 39.7 bits (91), Expect = 0.014
 Identities = 41/144 (28%), Positives = 55/144 (38%), Gaps = 8/144 (5%)

Query: 535  VTTRPSTEEPVRRPQRPRSPPLPAVIRNAPSRPPSLPTPRPASQPRKA--PVISSTPKLP 592
            V T PS +          +P  PA    +P   P  P P+ A  P     P    TP LP
Sbjct: 1291 VVTPPSPKGGPATSPPKGAPTPPAATPPSPKGSPGTPPPKGAPTPPAVTPPSPKGTPTLP 1350

Query: 593  ALAAREEASTSRLLQPPEAPRKPANTLVKTASRPAPLVQQLSPSLLPNSKSPREVP-SPK 651
            A     +   +      E P  PA T    + +  P +   SP   P   SP+  P SP 
Sbjct: 1351 ATTPSSKGGPT-TPSSKEGPTPPAAT---PSHKGGPAMTPPSPKRGPAIPSPKGDPTSPA 1406

Query: 652  VIKTPVVKKTESPI-KLSPATPSR 674
            VI     K   +P+ +   ATPS+
Sbjct: 1407 VIPLSPKKAPATPVTREGAATPSK 1430



 Score = 38.9 bits (89), Expect = 0.024
 Identities = 39/139 (28%), Positives = 48/139 (34%), Gaps = 9/139 (6%)

Query: 537  TRPSTEEPVRRPQRPRSPPLPAVIRNAPSRPPSLPTPRPASQPRKAPVISSTPKLPALAA 596
            T PS +  +  P    +P  PA     PS    L TP P   P      ++TP  P    
Sbjct: 1109 TPPSPKGGLATPPHKGAPTTPAA--TPPSPKGGLATPPPKGAPTTP---AATPPSPKGGL 1163

Query: 597  REEASTSRLLQPPEAPRKPANTLVKTASRPAPLVQQLSPSLLPNSKSPREVPSPKVIKTP 656
                       P   P  P   L   + + AP     +P   P+ K     PSPK   T 
Sbjct: 1164 ATPPPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATP---PSPKGGLATPSPKGAPTT 1220

Query: 657  VVKKTESPIKLSPATPSRK 675
                  SP K   ATPS K
Sbjct: 1221 PAATPPSP-KGGLATPSPK 1238



 Score = 37.0 bits (84), Expect = 0.090
 Identities = 43/157 (27%), Positives = 60/157 (38%), Gaps = 14/157 (8%)

Query: 509 QQEKLEALQKTTPIRSQADLKKLPLEVTTRPSTEEPVRRPQRPRSPPLPAVIRNAPSRPP 568
           QQ  L A  + +P  S + +   PLEV   P +      P    +P  P  + N    PP
Sbjct: 54  QQCPLSAANQASPFPSPSTIASTPLEVPF-PQSSSGTALPLGT-APEAPTFLPNLIG-PP 110

Query: 569 SLPTPRPASQPRKAPVISSTPK------LPALAAREEASTSRLLQPPEAPRKPANTLVKT 622
             P     + P  AP +  TP       L ALA      +S    PP     P +  V  
Sbjct: 111 ISPAALALASPMIAPTLKGTPSSSAPLALVALAPHSVQKSSAF--PPNLLTSPPSVAVAE 168

Query: 623 ASRPAPLVQQLSPSLLPN--SKSPRE-VPSPKVIKTP 656
           +     L   ++PS      +K P E VP+PK   +P
Sbjct: 169 SGSVITLSAPIAPSEPKTNLNKVPSEVVPNPKGTPSP 205



 Score = 37.0 bits (84), Expect = 0.090
 Identities = 40/142 (28%), Positives = 53/142 (37%), Gaps = 10/142 (7%)

Query: 537  TRPSTEEPVRRPQRPRSPPLPAVIRNAPSRPPSLPTPRPASQPRKAPVISSTPKLP-ALA 595
            T PS +  +  P    +P  PA     PS    L TP P   P        +PK   A  
Sbjct: 1178 TPPSPKGGLATPSPKGAPTTPAA--TPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATP 1235

Query: 596  AREEASTSRLLQPPEAPRKPANTLVKTASRPAPLVQQLSPSLLPNSKSP--REVPSPKVI 653
            + + A T+    PP     PA    K A  P        PSL     +P  +  P+P V+
Sbjct: 1236 SPKGAPTTPAATPPSPKGGPATPPPKGAPTPPAAT---PPSLKGGLATPPHKGAPNPAVV 1292

Query: 654  KTPVVK--KTESPIKLSPATPS 673
              P  K     SP K +P  P+
Sbjct: 1293 TPPSPKGGPATSPPKGAPTPPA 1314



 Score = 36.6 bits (83), Expect = 0.12
 Identities = 36/147 (24%), Positives = 54/147 (36%), Gaps = 20/147 (13%)

Query: 545  VRRPQRPRSPPLPAVIRNAPSRPPSLPTPR--PASQPRKAPVISSTPKLPALAAREEAST 602
            V  P    +P  PAV   +P + P+ P P+  P S P     +  +P  PA    +  +T
Sbjct: 1605 VTSPSPKEAPTPPAVTPPSPEKGPATPAPKGTPTSPPVTPSSLKDSPTSPASVTCKMGAT 1664

Query: 603  ----SRLLQPPEAPRKPANTLVKTASRPAPLVQQLSPSLLPNSKSPR----EVPSPKVIK 654
                S+ L   + P      LV  A    P++        P  K P+       SP +  
Sbjct: 1665 VPQASKGLPAKKGPTALKEVLVAPAPESTPII------TAPTRKGPQTKKSSATSPPICP 1718

Query: 655  TPVVKKTE----SPIKLSPATPSRKRS 677
             P  K       S +  +P  P +K S
Sbjct: 1719 DPSAKNGSKGPLSTVAPAPLLPVQKDS 1745



 Score = 34.3 bits (77), Expect = 0.58
 Identities = 39/155 (25%), Positives = 68/155 (43%), Gaps = 16/155 (10%)

Query: 531 LPLEVT-TRPSTEEPVRRPQRPRSPPLPAVIRNAPSRPPSLPTPRPASQPRKAPVISSTP 589
           +P E T T P+TE+ + +PQ   +  LP  + +A S   +L  P P   P  +P     P
Sbjct: 1   MPGEATETVPATEQELPQPQA-ETAVLP--MSSALSVTAALGQPGPTLPPPCSPAPQQCP 57

Query: 590 KLPALAAREEASTSRLLQPP---EAPRKPANTLVKTASRPAPLVQQLSPSLLPNSKSPRE 646
              A  A    S S +   P     P+  + T +   + P       +P+ LPN   P  
Sbjct: 58  LSAANQASPFPSPSTIASTPLEVPFPQSSSGTALPLGTAPE------APTFLPNLIGPPI 111

Query: 647 VPSPKVIKTPVVKKTESPIKLSPATPSRKRSVAVS 681
            P+   + +P++  T   +K +P++ +    VA++
Sbjct: 112 SPAALALASPMIAPT---LKGTPSSSAPLALVALA 143



 Score = 33.1 bits (74), Expect = 1.3
 Identities = 43/167 (25%), Positives = 60/167 (35%), Gaps = 14/167 (8%)

Query: 521  PIRSQADL--KKLPLEVTTRPSTEEPVRRPQRPRSPPLPAVIRNAPSRPPSLPTPRPASQ 578
            PI   A L  KK P  +  + +   P      P+  P     + AP+ P S      +S 
Sbjct: 1526 PIAPTATLLSKKTPATLAPKEALIPPAMTVPSPKKTPAIPTPKEAPATPSS---KEASSP 1582

Query: 579  PRKAPVISSTPKLPALAAREEASTSRLLQPPEAPRKPANT---LVKTASRPAPLVQQLSP 635
            P   P        P       A TS    P EAP  PA T     K  + PAP     SP
Sbjct: 1583 PAVTPSTYKGAPSPKELLIPPAVTSP--SPKEAPTPPAVTPPSPEKGPATPAPKGTPTSP 1640

Query: 636  SLLPNSKSPREVPSPKVIKTPVVKKTESPIKLSPATPSRKRSVAVSD 682
             + P+S       SP    +   K   +  + S   P++K   A+ +
Sbjct: 1641 PVTPSSLK----DSPTSPASVTCKMGATVPQASKGLPAKKGPTALKE 1683



 Score = 32.3 bits (72), Expect = 2.2
 Identities = 40/148 (27%), Positives = 60/148 (40%), Gaps = 19/148 (12%)

Query: 535  VTTRPSTEEPVRRPQRPRSPPL---PAVIRNAPSRP-------PSLPTPRPASQPRKAPV 584
            + T P+ + P  +     SPP+   P+  +N    P       P LP  + +S+  K   
Sbjct: 1695 IITAPTRKGPQTKKSSATSPPICPDPSA-KNGSKGPLSTVAPAPLLPVQKDSSKTAKGKD 1753

Query: 585  ISSTPKLPALAAREEASTSRLLQPPE-APRKPANTLVKTASRPAPLVQQLSPSLLPNSKS 643
             S +PK P      +AST       E    KP +  V  A  P P+   L+PS +P    
Sbjct: 1754 ASHSPKGPLAPPESKASTPLTAAAFEKVLPKPESASVSAAPSP-PVSLPLAPSPVPTLP- 1811

Query: 644  PREVPSPKVIKTPVVKKTESPIK-LSPA 670
                P  + + +      ESP K L+PA
Sbjct: 1812 ----PKQQFLPSSPGLVLESPSKPLAPA 1835


>gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens]
          Length = 1020

 Score = 60.8 bits (146), Expect = 6e-09
 Identities = 60/272 (22%), Positives = 111/272 (40%), Gaps = 42/272 (15%)

Query: 467  PDPEQDRCEASE--QKQKVPLGTFRKDMKTQEEKQKQLTEKIRQQQEKLEALQKTTPIRS 524
            P  E+ R  A +  +K K P+   ++++K+ E+ +  L E  +  ++++    K   ++S
Sbjct: 769  PAKEEARSPADKFPEKAKSPV---KEEVKSPEKAKSPLKEDAKAPEKEIP---KKEEVKS 822

Query: 525  QADLKKLPLEVTTRPSTEEPVRRPQRPRSPPLPAVIRNAPSRPPSLP---TPRPASQPRK 581
                ++ P EV  +    EP ++ +  ++P  P       S+    P    P+P  + +K
Sbjct: 823  PVKEEEKPQEVKVK----EPPKKAEEEKAPATPKTEEKKDSKKEEAPKKEAPKPKVEEKK 878

Query: 582  APVISSTPKLPALAAREEASTSRLLQPPEAPRKPANTLVKTASRPAPLVQQLSPSLLPNS 641
             P +    +    A +EEA   + +  PE    PA   VK  ++P               
Sbjct: 879  EPAVEKPKESKVEAKKEEAEDKKKVPTPEK-EAPAKVEVKEDAKPKE------------- 924

Query: 642  KSPREVPSPKVIKTPVVKKTESPIKLS-PATPSRKRSVAVSDEEEVEEEAERRKERCKRG 700
                        KT V KK     K   P+ P+ K+  A   ++  EE+A++ +E+ K  
Sbjct: 925  ------------KTEVAKKEPDDAKAKEPSKPAEKKEAAPEKKDTKEEKAKKPEEKPKTE 972

Query: 701  RFVVKEEKKDSNELSDSAGEEDSADLKRAQKD 732
                +++K  S E S    E+        QKD
Sbjct: 973  AKAKEDDKTLSKEPSKPKAEKAEKSSSTDQKD 1004



 Score = 58.9 bits (141), Expect = 2e-08
 Identities = 84/384 (21%), Positives = 152/384 (39%), Gaps = 43/384 (11%)

Query: 470 EQDRCEASEQKQKVP----LGTFRKDMKT--QEEKQKQLTEKIRQQQEKLEALQKTTPIR 523
           E++  E  E++ K P      +  K+ K+  +EE +     K  +++E     +  +P +
Sbjct: 490 EEEEAEGGEEETKSPPAEEAASPEKEAKSPVKEEAKSPAEAKSPEKEEAKSPAEVKSPEK 549

Query: 524 SQADLK---KLPLEVTTRPSTEEP-----VRRPQRPRSPPLPAVIRNAPSRPPSLPTPRP 575
           +++  K   K P E  + P  EE      V+ P++ +SP        A ++ P      P
Sbjct: 550 AKSPAKEEAKSPPEAKS-PEKEEAKSPAEVKSPEKAKSPAKEEAKSPAEAKSPE-KAKSP 607

Query: 576 ASQPRKAPVISSTPKLPALAAREEASTSRLLQPPEAPRKPANTLVKTASRP-------AP 628
             +  K+P  + +P       +EEA +   ++ PE  + P     K+  +        A 
Sbjct: 608 VKEEAKSPAEAKSP------VKEEAKSPAEVKSPEKAKSPTKEEAKSPEKAKSPEKEEAK 661

Query: 629 LVQQLSPSLLPNSKSPREVPSPKVIKTPVVKKTESPIKLSPATPSRKRSVAVSDEEEVEE 688
             ++    +   +KSP +  SP   +    +K +SP+K    +P + +S    + +  E+
Sbjct: 662 SPEKAKSPVKAEAKSPEKAKSPVKAEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKSPEK 721

Query: 689 EAERRKERCK---RGRFVVKEEKKDSNELSDSAGEEDSADLKRAQKDKGLHVEVRVNREW 745
                KE  K   + +  VKEE K S E + S  +  + D+K  +       E R   + 
Sbjct: 722 AKSPVKEEAKTPEKAKSPVKEEAK-SPEKAKSPEKAKTLDVKSPEAKTPAKEEARSPADK 780

Query: 746 YTGRVTAVEVGKHVVRWKVKFDYVPTDTTPRD-RWVEKGSEDVRLMKPPSPEHQSLDTQQ 804
           +       E  K  V+ +VK           D +  EK       +K P  E +     Q
Sbjct: 781 FP------EKAKSPVKEEVKSPEKAKSPLKEDAKAPEKEIPKKEEVKSPVKEEEK---PQ 831

Query: 805 EGGEEEVGPVAQQAIAVAEPSTSE 828
           E   +E    A++  A A P T E
Sbjct: 832 EVKVKEPPKKAEEEKAPATPKTEE 855



 Score = 49.3 bits (116), Expect = 2e-05
 Identities = 86/369 (23%), Positives = 141/369 (38%), Gaps = 51/369 (13%)

Query: 497 EKQKQLTEKIRQQQEKLEALQKTTPIRSQADLKKLPLEVTTRPSTEEPVRR----PQRPR 552
           EK K  T++  +  EK ++ +K      +     +  E  +    + PV+     P++ +
Sbjct: 636 EKAKSPTKEEAKSPEKAKSPEKEEAKSPEKAKSPVKAEAKSPEKAKSPVKAEAKSPEKAK 695

Query: 553 SPPLPAVIRNAPSRPPSLPTPRPASQPRKA--PVI--SSTPKLPALAAREEASTSRLLQP 608
           SP        +P +  S P    A  P KA  PV   + TP+      +EEA +    + 
Sbjct: 696 SPVKEEA--KSPEKAKS-PVKEEAKSPEKAKSPVKEEAKTPEKAKSPVKEEAKSPEKAKS 752

Query: 609 PEAPRKPANTL-VKTASRPAPLVQQLSPSLLPNSKSPREVPSPKVIKTPVVKKTESPIKL 667
           PE     A TL VK+     P  ++      P  K P +  SP   +    +K +SP+K 
Sbjct: 753 PEK----AKTLDVKSPEAKTPAKEEARS---PADKFPEKAKSPVKEEVKSPEKAKSPLKE 805

Query: 668 SPATPSRKRSVAVSDEEEVEEEAERRKERCKRGRFVVKEEK----KDSNELSDSAGEEDS 723
               P ++       +  V+EE + ++ + K      +EEK      + E  DS  EE  
Sbjct: 806 DAKAPEKEIPKKEEVKSPVKEEEKPQEVKVKEPPKKAEEEKAPATPKTEEKKDSKKEE-- 863

Query: 724 ADLKRAQKDKGLHVEVRVNREWYTGRVTAVEVGKHVVRWKVKFDYVPT------------ 771
           A  K A K K   VE +        + + VE  K     K K   VPT            
Sbjct: 864 APKKEAPKPK---VEEKKEPAVEKPKESKVEAKKEEAEDKKK---VPTPEKEAPAKVEVK 917

Query: 772 -DTTPRDRW--VEKGSEDVRLMKPPSPEHQSLDTQQEGGEEEVGPVAQQAIAVAEPSTSE 828
            D  P+++    +K  +D +  +P  P       ++E   E+     ++A    E   +E
Sbjct: 918 EDAKPKEKTEVAKKEPDDAKAKEPSKPAE-----KKEAAPEKKDTKEEKAKKPEEKPKTE 972

Query: 829 CLRIEPDTT 837
               E D T
Sbjct: 973 AKAKEDDKT 981



 Score = 30.4 bits (67), Expect = 8.4
 Identities = 66/316 (20%), Positives = 114/316 (36%), Gaps = 71/316 (22%)

Query: 470 EQDRCEASEQKQKVPLGTFRKDMKTQEEKQKQLTEKIRQQQEKLEALQKTTPIRSQADLK 529
           E+ R E  ++ Q         D+ + +E  +QL  ++R  + ++ A      +R   DL 
Sbjct: 343 ERQRSELEDRHQA--------DIASYQEAIQQLDAELRNTKWEMAA-----QLREYQDLL 389

Query: 530 KLPLEVTTRPSTEEPVRRPQRPRSP--PLPAVIRNAPSRPPSLPTPRPASQPRKAPVISS 587
            + + +    +    +   +  R    P+P  +     + PS+ T        K  V+  
Sbjct: 390 NVKMALDIEIAAYRKLLEGEECRIGFGPIPFSLPEGLPKIPSVSTHIKVKSEEKIKVVEK 449

Query: 588 TPKLPALAAREEASTSRLLQPPEAPRKPANTLV-----------------KTASRPA--- 627
           + K   +   +   T    +  E   K A                     +T S PA   
Sbjct: 450 SEKETVIVEEQTEETQVTEEVTEEEEKEAKEEEGKEEEGGEEEEAEGGEEETKSPPAEEA 509

Query: 628 --PLVQQLSPSLLPNSKSPREVPSPK--------VIKTPVVKKTESPIKLSPATPSRKRS 677
             P  +  SP +   +KSP E  SP+         +K+P  +K +SP K    +P   +S
Sbjct: 510 ASPEKEAKSP-VKEEAKSPAEAKSPEKEEAKSPAEVKSP--EKAKSPAKEEAKSPPEAKS 566

Query: 678 VAVSDEEEVEEEAERR---------KERCK---------RGRFVVKEEKKDSNELSDSAG 719
               ++EE +  AE +         KE  K         + +  VKEE K   E      
Sbjct: 567 ---PEKEEAKSPAEVKSPEKAKSPAKEEAKSPAEAKSPEKAKSPVKEEAKSPAEAKSPVK 623

Query: 720 EE--DSADLKRAQKDK 733
           EE    A++K  +K K
Sbjct: 624 EEAKSPAEVKSPEKAK 639


>gi|78042577 MAP7 domain containing 1 [Homo sapiens]
          Length = 841

 Score = 58.9 bits (141), Expect = 2e-08
 Identities = 69/281 (24%), Positives = 111/281 (39%), Gaps = 24/281 (8%)

Query: 466 NPDPEQDRCEASEQKQKVPLGTFRKDMKTQEEKQKQLTEKIRQQQEKLEALQKTTPIRSQ 525
           +P P + R EAS  ++K      +KD + + EK+K    + R  +++           S 
Sbjct: 399 SPAPVRRRPEASPVQKKE-----KKDKERENEKEKSALARERSLKKRQSLPASPRARLSA 453

Query: 526 ADLKKLPLEVTTRPSTEEPVRRPQRPRSP-PLPAVIRNAPSRPPSLPTPRPASQPRKAPV 584
           +   +L  +   RPS+  P     RP SP P P      P +PPS P    AS   +   
Sbjct: 454 STASELSPKSKARPSS--PSTSWHRPASPCPSPGPGHTLPPKPPS-PRGTTASPKGRVRR 510

Query: 585 ISSTPKLPALAAREEASTSRLLQPPEAPRKPANTLVKTA-SRPAPLVQQLSPSLLPNSKS 643
                + P+ A  E+ S S+        R+ +N     A + PAP     SP+  P    
Sbjct: 511 KEEAKESPSAAGPEDKSQSK--------RRASNEKESAAPASPAP-----SPAPSPTPAP 557

Query: 644 PREVPSPKVIKTPVVKKTESPIKLSPATPSRKRSVAVSDEEEVEEEAERRKERCKRGRFV 703
           P++   P    T     T  P    P TPS+  +     EE     AE+R++  +  R  
Sbjct: 558 PQKEQPPAETPTDAAVLTSPPAPAPPVTPSKPMAGTTDREEATRLLAEKRRQ-AREQRER 616

Query: 704 VKEEKKDSNELSDSAGEEDSADLKRAQKDKGLHVEVRVNRE 744
            ++E++   E      EE  A    A+ ++      R  +E
Sbjct: 617 EEQERRLQAERDKRMREEQLAREAEARAEREAEARRREEQE 657



 Score = 43.9 bits (102), Expect = 7e-04
 Identities = 54/200 (27%), Positives = 82/200 (41%), Gaps = 21/200 (10%)

Query: 557 PAVIRNAPSRPPSLPT--PRPASQPRKAPVISSTPKLPALAAREEASTSRLLQPPEAPRK 614
           PAV+   P  P   P   P P   P  A V  + P  P   A + A++S+ L     P +
Sbjct: 15  PAVVARTPPEPRPSPEGDPSPPPPPMSALVPDTPPDTP--PAMKNATSSKQL-----PLE 67

Query: 615 PANTLVKTASRPAPLVQQLSPSLLPNSKSPR-EVPSPKVIKTPVVKKTESPIKLSPA-TP 672
           P +   +   RPAP  Q+ SPS    S+ P      P+  + P      SP  +  + +P
Sbjct: 68  PESPSGQVGPRPAP-PQEESPSSEAKSRGPTPPAMGPRDARPPRRSSQPSPTAVPASDSP 126

Query: 673 SRKRSVAVSDEEEVEEEAERRKER-----CKRGRFVVKEEKKDS---NELSDSAGEEDSA 724
             K+ V  + E   +   ERR+ER      K+  ++ KEEK  +    +L +     +  
Sbjct: 127 PTKQEVKKAGERH-KLAKERREERAKYLAAKKAVWLEKEEKAKALREKQLQERRRRLEEQ 185

Query: 725 DLKRAQKDKGLHVEVRVNRE 744
            LK  Q+   L    R   E
Sbjct: 186 RLKAEQRRAALEERQRQKLE 205



 Score = 38.1 bits (87), Expect = 0.040
 Identities = 45/209 (21%), Positives = 84/209 (40%), Gaps = 15/209 (7%)

Query: 543 EPVRRPQRPRSPPLPAVIRNAPSRPPSL-PTPRPASQPRKAPVISSTPK-----LPALAA 596
           EP   P+   SPP P +    P  PP   P  + A+  ++ P+   +P       PA   
Sbjct: 24  EPRPSPEGDPSPPPPPMSALVPDTPPDTPPAMKNATSSKQLPLEPESPSGQVGPRPAPPQ 83

Query: 597 REEASTSRLLQPPEAPRKPANTLVKTASRPAPLVQQLSPSLLPNSKSPREVPSPKVIKTP 656
            E  S+    + P  P      +    +RP     Q SP+ +P S SP   P+ + +K  
Sbjct: 84  EESPSSEAKSRGPTPP-----AMGPRDARPPRRSSQPSPTAVPASDSP---PTKQEVKKA 135

Query: 657 VVKKTESPIKLSPATPSRKRSVAVSDEEEVEEEAERRKERCKRGRFVVKEEKKDSNELSD 716
             +   +  +            AV  E+E + +A R K+  +R R  ++E++  + +   
Sbjct: 136 GERHKLAKERREERAKYLAAKKAVWLEKEEKAKALREKQLQERRR-RLEEQRLKAEQRRA 194

Query: 717 SAGEEDSADLKRAQKDKGLHVEVRVNREW 745
           +  E     L++ ++     ++  V + W
Sbjct: 195 ALEERQRQKLEKNKERYEAAIQRSVKKTW 223



 Score = 36.2 bits (82), Expect = 0.15
 Identities = 39/171 (22%), Positives = 77/171 (45%), Gaps = 11/171 (6%)

Query: 470 EQDRCEASEQKQKVPLGTFRKDMKTQEEKQKQLTEKIRQQQEKLEALQK---TTPIRSQA 526
           E+D+    EQ  +       ++ + +  ++++  EK + +QE+ E LQK       RS+ 
Sbjct: 626 ERDKRMREEQLAREAEARAEREAEARRREEQEAREKAQAEQEEQERLQKQKEEAEARSRE 685

Query: 527 DLKKLPLEVTTRPSTEEPVRRPQRPRSPPLPAVIRNAPSRPPSLPTPRPASQPRKAPVIS 586
           + ++  LE       +E  R+ +R R   L  +++   +R   +   +     ++A    
Sbjct: 686 EAERQRLEREKHFQQQEQERQERRKR---LEEIMKR--TRKSEVSETKQKQDSKEANANG 740

Query: 587 STPK-LPALAAREEASTSRLLQPPE-APRKPANTLVKTASRPAPLVQQLSP 635
           S+P+ + A+ AR        +Q  E  P++P  +L  +   PA LV  L P
Sbjct: 741 SSPEPVKAVEARSPGLQKEAVQKEEPIPQEPQWSL-PSKELPASLVNGLQP 790


>gi|189181724 proteoglycan 4 isoform D [Homo sapiens]
          Length = 1270

 Score = 57.8 bits (138), Expect = 5e-08
 Identities = 55/185 (29%), Positives = 77/185 (41%), Gaps = 36/185 (19%)

Query: 520 TPIRSQADLKKLPLEVTTRPS-----------TEEPVRRPQRPRSP-------PLPAVIR 561
           T I+S     K P   TT+ +           T+EP   P  P+ P       P P   +
Sbjct: 235 TTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPA--PTTPKEPAPTTTKEPAPTTTK 292

Query: 562 NAPSRP-------PSLPTP----RPASQPRKAPVISSTPKLPALAAREEASTSRLLQPPE 610
           +AP+ P       P  P P     PA    K P   +TPK PA   +E A T+     P 
Sbjct: 293 SAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPT-PTTPKEPAPTTKEPAPTTPKEPAPT 351

Query: 611 APRKPANTLVKTASRPAPLVQQLSPSLLPNSKSPREVPSPKVIKT-PVVKKTESP--IKL 667
           AP+KPA T  K  +   P     + +  P+  +P+E P+P   K+ P   K  +P   K 
Sbjct: 352 APKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKE-PAPTTTKSAPTTTKEPAPTTTKS 410

Query: 668 SPATP 672
           +P TP
Sbjct: 411 APTTP 415



 Score = 56.2 bits (134), Expect = 1e-07
 Identities = 52/201 (25%), Positives = 76/201 (37%), Gaps = 24/201 (11%)

Query: 493 KTQEEKQKQLTEKIRQQQ--EKLEALQKTTPIRSQADLKKLPLEVTTRPSTEEPVRRPQR 550
           KT   K+ Q  EK   +      + L K TP +++   K   L     P+   P      
Sbjct: 169 KTTSAKETQSIEKTSAKDLAPTSKVLAKPTP-KAETTTKGPALTTPKEPTPTTPKEPAST 227

Query: 551 PRSPPLPAVIRNAPSRPP--------SLPT----PRPASQPRKAPVISSTPKLPALAARE 598
               P P  I++AP+ P         S PT    P P +    AP   +TPK PA    +
Sbjct: 228 TPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAP---TTPKEPAPTTTK 284

Query: 599 EASTSRLLQPPEAPRKPANTLVK-----TASRPAPLVQQLSPSLLPNSKSP-REVPSPKV 652
           E + +     P  P++PA T  K     T   PAP   +      P   +P  + P+P  
Sbjct: 285 EPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTT 344

Query: 653 IKTPVVKKTESPIKLSPATPS 673
            K P     + P   +P  P+
Sbjct: 345 PKEPAPTAPKKPAPTTPKEPA 365



 Score = 51.6 bits (122), Expect = 4e-06
 Identities = 44/171 (25%), Positives = 66/171 (38%), Gaps = 23/171 (13%)

Query: 519 TTPIRSQADLKKLPLEVTTR---PSTEEPVRRPQRPRSPPLPAVIRNAPSRP-------P 568
           TTP        K P   T +   P+T+EP   P  P+ P   A  + AP+ P       P
Sbjct: 312 TTPKEPAPTTPKEPTPTTPKEPAPTTKEPA--PTTPKEPAPTAPKKPAPTTPKEPAPTTP 369

Query: 569 SLPTPRPASQPR----KAPVISSTPKLPALAAREEASTSRLLQPPEAPRKPANTLVKTAS 624
             P P    +P     K P  ++T   P        +T++    P  P++P+ T   T  
Sbjct: 370 KEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTK--SAPTTPKEPSPT---TTK 424

Query: 625 RPAPLVQQLSPSLLPNSKSPR--EVPSPKVIKTPVVKKTESPIKLSPATPS 673
            PAP   +      P   +P   + P+P   K P    T+ P   +P  P+
Sbjct: 425 EPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPA 475



 Score = 49.7 bits (117), Expect = 1e-05
 Identities = 53/221 (23%), Positives = 76/221 (34%), Gaps = 23/221 (10%)

Query: 468 DPEQDRCEASEQKQKVPLGTFRKDMKTQEEKQKQLTEKIRQQQEKLEALQKTTPIRSQAD 527
           +P     +++    K P  T  K   T  ++    T K        E    TT   +   
Sbjct: 231 EPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTT 290

Query: 528 LKKLPLEVTTRPSTEEPVRRPQRPRSPPLPAVIRNAPSRP--PSLPTPRPASQPRKAPVI 585
            K  P        T      P  P+ P         P+ P  P+  T  PA    K P  
Sbjct: 291 TKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPA- 349

Query: 586 SSTPKLPALAA---------REEASTSRLLQPPEAPRKPANTLVK----TASRPAPLVQQ 632
            + PK PA            +E A T+     P  P++PA T  K    T   PAP   +
Sbjct: 350 PTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTK 409

Query: 633 LSPSLLPNSKSPREVPSPKVIKTPVVKKTESPIKLSPATPS 673
            +P+      +P+E PSP   K P     + P   +P  P+
Sbjct: 410 SAPT------TPKE-PSPTTTKEPAPTTPKEPAPTTPKKPA 443



 Score = 49.3 bits (116), Expect = 2e-05
 Identities = 44/160 (27%), Positives = 62/160 (38%), Gaps = 13/160 (8%)

Query: 519 TTPIRSQADLKKLPLEVTTRPSTEEPVRRPQRPRSPPLPAVIRNAPSRP--PSLPT---P 573
           TTP        K P   T +       +        P P   ++AP+ P  PS  T   P
Sbjct: 367 TTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEP 426

Query: 574 RPASQPRKAPVISSTPKLPALAAREEASTSRLLQP-PEAPRKPANTLVKTASRPAPLVQQ 632
            P +    AP   +TPK PA    +E + +   +P P   +KPA T   T   PAP   +
Sbjct: 427 APTTPKEPAP---TTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPT---TPKEPAPTTPK 480

Query: 633 LSPSLLPNSKSPREVPSPKVIKTPVVKKTESPIKLSPATP 672
            +    P   +P   P      TP      +P +L+P TP
Sbjct: 481 ETAPTTPKKLTP-TTPEKLAPTTPEKPAPTTPEELAPTTP 519



 Score = 47.0 bits (110), Expect = 9e-05
 Identities = 52/213 (24%), Positives = 81/213 (38%), Gaps = 12/213 (5%)

Query: 468 DPEQDRCEASEQKQKVPLGTFRKDMKTQEEKQKQLTEKIRQQQEKLEALQKTTPIRSQAD 527
           +P     +++    K P  T  K   T  ++    T K        E    TTP +    
Sbjct: 387 EPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAP-TTPKKPAPT 445

Query: 528 LKKLPLEVTTRPSTEEPVRRPQRPRSPPLPAVIRNAPSRPPSLPTPRPASQPRKAPVISS 587
             K P   T +       ++P  P +P  PA      + P +     P +  + AP   +
Sbjct: 446 TPKEPAPTTPKEPAPTTTKKPA-PTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAP---T 501

Query: 588 TPKLPALAAREEASTSRLLQP-PEAPRKPANTLVKTASRPAPLVQQLSPSLLPNSKSPRE 646
           TP+ PA    EE + +   +P P  P +PA T  K A+   P     +    P   +P+E
Sbjct: 502 TPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKE 561

Query: 647 VPSPKVIK--TPVVKKTESPIKL---SPATPSR 674
            P+P   K   P   K  +P  L   +P TP +
Sbjct: 562 -PAPTTPKETAPTTPKGTAPTTLKEPAPTTPKK 593



 Score = 44.3 bits (103), Expect = 6e-04
 Identities = 51/214 (23%), Positives = 73/214 (34%), Gaps = 17/214 (7%)

Query: 475 EASEQKQKVPLGTFRKDMKTQEEKQKQLTEKIRQQQEKLEALQKTTPIRSQADLKKLPLE 534
           E +    K P  T  K+      K+   T   +      E L  TTP   +      P E
Sbjct: 457 EPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTP---EKPAPTTPEE 513

Query: 535 VTTRPSTEEPVRRPQRPRSPPLPAVIRNAPSRPPSLPTPRPASQPRKAPVISSTPKLPAL 594
           +      E     P+ P      A   N P  P       PA    K P   +TPK  A 
Sbjct: 514 LAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPA-PTTPKETAP 572

Query: 595 AAREEASTSRLLQP-PEAPRKP-----ANTLVK-----TASRPAPLVQQLSPSLLPNSKS 643
              +  + + L +P P  P+KP     A T  K     T  +PAP   + +    P   +
Sbjct: 573 TTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPA 632

Query: 644 PR--EVPSPKVIKTPVVKKTESPIKLSPATPSRK 675
           P   + P+P   K       + P   +P  P+ K
Sbjct: 633 PTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPK 666



 Score = 42.4 bits (98), Expect = 0.002
 Identities = 43/164 (26%), Positives = 62/164 (37%), Gaps = 21/164 (12%)

Query: 536 TTRPSTEEPVRRPQRPRSPPLPAVIRNAPSRPPSLPTPRPASQPRKAPV----------I 585
           TT   T     +   P +P  PA      + P +L  P P +  + AP            
Sbjct: 618 TTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPT 677

Query: 586 SSTPKLPALAAREEASTSRLLQP-PEAPRKPANTLVKTASRPAPLVQQLSPSLLPNS--- 641
           S+T   PA    +E + +   +P P  P+KPA T   T   P P   ++S          
Sbjct: 678 STTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPT---TPETPPPTTSEVSTPTTTKEPTT 734

Query: 642 --KSPREVPSPKVIKTPVVKKTESPIKLSPATPSRKRSVAVSDE 683
             KSP E  +P++   P  K  E+  K  P  P+ K   A   E
Sbjct: 735 IHKSPDE-STPELSAEPTPKALENSPK-EPGVPTTKTPAATKPE 776



 Score = 38.5 bits (88), Expect = 0.031
 Identities = 35/120 (29%), Positives = 55/120 (45%), Gaps = 24/120 (20%)

Query: 571 PTPRPASQPRKAPVISSTPKLPALAAREEASTSRLLQP--------PEAPRKPANTLVKT 622
           PTP+ A    K P ++ TPK P     +E +++   +P        P  P++PA T  K+
Sbjct: 197 PTPK-AETTTKGPALT-TPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKS 254

Query: 623 A----SRPAPLVQQLSPSLLPNSKSPREVPSPKVIKTPVVKKTES----PIKLSPATPSR 674
           A      PAP     + +  P   +P+E P+P   K P    T+S    P + +P TP +
Sbjct: 255 APTTPKEPAP-----TTTKEPAPTTPKE-PAPTTTKEPAPTTTKSAPTTPKEPAPTTPKK 308



 Score = 38.1 bits (87), Expect = 0.040
 Identities = 43/226 (19%), Positives = 82/226 (36%), Gaps = 18/226 (7%)

Query: 519 TTPIRSQADLKKLPLEVT--TRPSTEEPVRRPQRPRSPPLPAVIRNAPSRPPSL---PTP 573
           TTP        K P   T  T P T   V  P   + P    + ++     P L   PTP
Sbjct: 695 TTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPT--TIHKSPDESTPELSAEPTP 752

Query: 574 RPASQPRKAPVISSTPKLPALAAREEASTSRLLQPPEAPRKPANTLVKTASRPAPLVQQL 633
           +      K P + +T K PA    E  +T++     +   +   T  +T +    + ++ 
Sbjct: 753 KALENSPKEPGVPTT-KTPAATKPEMTTTAK----DKTTERDLRTTPETTTAAPKMTKET 807

Query: 634 SPSLLPNSKSPREVPSPKVIKTPVVKKTESPIK------LSPATPSRKRSVAVSDEEEVE 687
           + +    ++S     + +V  T     T   I       L+P   + K+++  ++     
Sbjct: 808 ATTTEKTTESKITATTTQVTSTTTQDTTPFKITTLKTTTLAPKVTTTKKTITTTEIMNKP 867

Query: 688 EEAERRKERCKRGRFVVKEEKKDSNELSDSAGEEDSADLKRAQKDK 733
           EE  + K+R    +    + +K +         +    + R +K K
Sbjct: 868 EETAKPKDRATNSKATTPKPQKPTKAPKKPTSTKKPKTMPRVRKPK 913



 Score = 37.0 bits (84), Expect = 0.090
 Identities = 48/220 (21%), Positives = 84/220 (38%), Gaps = 32/220 (14%)

Query: 458 PDTWVCSMNPDPEQDRCEASEQKQKVPLGTFRKDMKTQEEKQKQLTEKIRQQQEKLEALQ 517
           PD     ++ +P     E S ++  VP        KT    + ++T           A  
Sbjct: 739 PDESTPELSAEPTPKALENSPKEPGVPT------TKTPAATKPEMTTT---------AKD 783

Query: 518 KTTPIRSQADLKKLPLEVTTRPS-TEEPVRRPQRPRSPPLPAVIRNAPSRPPSLPTPRPA 576
           KTT    + DL+  P   T  P  T+E     ++     + A      S      T    
Sbjct: 784 KTT----ERDLRTTPETTTAAPKMTKETATTTEKTTESKITATTTQVTS------TTTQD 833

Query: 577 SQPRKAPVISSTPKLPALAAREEA-STSRLLQPPEAPRKPANTLVKT-ASRPAPLVQQLS 634
           + P K   + +T   P +   ++  +T+ ++  PE   KP +    + A+ P P     +
Sbjct: 834 TTPFKITTLKTTTLAPKVTTTKKTITTTEIMNKPEETAKPKDRATNSKATTPKPQKPTKA 893

Query: 635 PSLLPNSKSPREVP---SPKVIKTPVVKKTESPIKLSPAT 671
           P    ++K P+ +P    PK   TP  K T +  +L+P +
Sbjct: 894 PKKPTSTKKPKTMPRVRKPKTTPTP-RKMTSTMPELNPTS 932



 Score = 32.7 bits (73), Expect = 1.7
 Identities = 23/94 (24%), Positives = 37/94 (39%), Gaps = 4/94 (4%)

Query: 519 TTPIRSQADLKKLPLEVTTRPSTEEPVRRPQRPRSPPLPAVIRNAPSRPPSLPTPRPASQ 578
           TT I ++ +    P +  T      P  +PQ+P   P        P   P +  P+    
Sbjct: 860 TTEIMNKPEETAKPKDRATNSKATTP--KPQKPTKAPKKPTSTKKPKTMPRVRKPKTTPT 917

Query: 579 PRKAPVISSTPKLPALAAREEASTSRLLQPPEAP 612
           PRK  + S+ P+L   +   EA      +P + P
Sbjct: 918 PRK--MTSTMPELNPTSRIAEAMLQTTTRPNQTP 949


>gi|189181722 proteoglycan 4 isoform C [Homo sapiens]
          Length = 1311

 Score = 57.8 bits (138), Expect = 5e-08
 Identities = 55/185 (29%), Positives = 77/185 (41%), Gaps = 36/185 (19%)

Query: 520 TPIRSQADLKKLPLEVTTRPS-----------TEEPVRRPQRPRSP-------PLPAVIR 561
           T I+S     K P   TT+ +           T+EP   P  P+ P       P P   +
Sbjct: 276 TTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPA--PTTPKEPAPTTTKEPAPTTTK 333

Query: 562 NAPSRP-------PSLPTP----RPASQPRKAPVISSTPKLPALAAREEASTSRLLQPPE 610
           +AP+ P       P  P P     PA    K P   +TPK PA   +E A T+     P 
Sbjct: 334 SAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPT-PTTPKEPAPTTKEPAPTTPKEPAPT 392

Query: 611 APRKPANTLVKTASRPAPLVQQLSPSLLPNSKSPREVPSPKVIKT-PVVKKTESP--IKL 667
           AP+KPA T  K  +   P     + +  P+  +P+E P+P   K+ P   K  +P   K 
Sbjct: 393 APKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKE-PAPTTTKSAPTTTKEPAPTTTKS 451

Query: 668 SPATP 672
           +P TP
Sbjct: 452 APTTP 456



 Score = 56.2 bits (134), Expect = 1e-07
 Identities = 52/201 (25%), Positives = 76/201 (37%), Gaps = 24/201 (11%)

Query: 493 KTQEEKQKQLTEKIRQQQ--EKLEALQKTTPIRSQADLKKLPLEVTTRPSTEEPVRRPQR 550
           KT   K+ Q  EK   +      + L K TP +++   K   L     P+   P      
Sbjct: 210 KTTSAKETQSIEKTSAKDLAPTSKVLAKPTP-KAETTTKGPALTTPKEPTPTTPKEPAST 268

Query: 551 PRSPPLPAVIRNAPSRPP--------SLPT----PRPASQPRKAPVISSTPKLPALAARE 598
               P P  I++AP+ P         S PT    P P +    AP   +TPK PA    +
Sbjct: 269 TPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAP---TTPKEPAPTTTK 325

Query: 599 EASTSRLLQPPEAPRKPANTLVK-----TASRPAPLVQQLSPSLLPNSKSP-REVPSPKV 652
           E + +     P  P++PA T  K     T   PAP   +      P   +P  + P+P  
Sbjct: 326 EPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTT 385

Query: 653 IKTPVVKKTESPIKLSPATPS 673
            K P     + P   +P  P+
Sbjct: 386 PKEPAPTAPKKPAPTTPKEPA 406



 Score = 51.6 bits (122), Expect = 4e-06
 Identities = 44/171 (25%), Positives = 66/171 (38%), Gaps = 23/171 (13%)

Query: 519 TTPIRSQADLKKLPLEVTTR---PSTEEPVRRPQRPRSPPLPAVIRNAPSRP-------P 568
           TTP        K P   T +   P+T+EP   P  P+ P   A  + AP+ P       P
Sbjct: 353 TTPKEPAPTTPKEPTPTTPKEPAPTTKEPA--PTTPKEPAPTAPKKPAPTTPKEPAPTTP 410

Query: 569 SLPTPRPASQPR----KAPVISSTPKLPALAAREEASTSRLLQPPEAPRKPANTLVKTAS 624
             P P    +P     K P  ++T   P        +T++    P  P++P+ T   T  
Sbjct: 411 KEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTK--SAPTTPKEPSPT---TTK 465

Query: 625 RPAPLVQQLSPSLLPNSKSPR--EVPSPKVIKTPVVKKTESPIKLSPATPS 673
            PAP   +      P   +P   + P+P   K P    T+ P   +P  P+
Sbjct: 466 EPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPA 516



 Score = 49.7 bits (117), Expect = 1e-05
 Identities = 53/221 (23%), Positives = 76/221 (34%), Gaps = 23/221 (10%)

Query: 468 DPEQDRCEASEQKQKVPLGTFRKDMKTQEEKQKQLTEKIRQQQEKLEALQKTTPIRSQAD 527
           +P     +++    K P  T  K   T  ++    T K        E    TT   +   
Sbjct: 272 EPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTT 331

Query: 528 LKKLPLEVTTRPSTEEPVRRPQRPRSPPLPAVIRNAPSRP--PSLPTPRPASQPRKAPVI 585
            K  P        T      P  P+ P         P+ P  P+  T  PA    K P  
Sbjct: 332 TKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPA- 390

Query: 586 SSTPKLPALAA---------REEASTSRLLQPPEAPRKPANTLVK----TASRPAPLVQQ 632
            + PK PA            +E A T+     P  P++PA T  K    T   PAP   +
Sbjct: 391 PTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTK 450

Query: 633 LSPSLLPNSKSPREVPSPKVIKTPVVKKTESPIKLSPATPS 673
            +P+      +P+E PSP   K P     + P   +P  P+
Sbjct: 451 SAPT------TPKE-PSPTTTKEPAPTTPKEPAPTTPKKPA 484



 Score = 49.3 bits (116), Expect = 2e-05
 Identities = 44/160 (27%), Positives = 62/160 (38%), Gaps = 13/160 (8%)

Query: 519 TTPIRSQADLKKLPLEVTTRPSTEEPVRRPQRPRSPPLPAVIRNAPSRP--PSLPT---P 573
           TTP        K P   T +       +        P P   ++AP+ P  PS  T   P
Sbjct: 408 TTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEP 467

Query: 574 RPASQPRKAPVISSTPKLPALAAREEASTSRLLQP-PEAPRKPANTLVKTASRPAPLVQQ 632
            P +    AP   +TPK PA    +E + +   +P P   +KPA T   T   PAP   +
Sbjct: 468 APTTPKEPAP---TTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPT---TPKEPAPTTPK 521

Query: 633 LSPSLLPNSKSPREVPSPKVIKTPVVKKTESPIKLSPATP 672
            +    P   +P   P      TP      +P +L+P TP
Sbjct: 522 ETAPTTPKKLTP-TTPEKLAPTTPEKPAPTTPEELAPTTP 560



 Score = 47.0 bits (110), Expect = 9e-05
 Identities = 52/213 (24%), Positives = 81/213 (38%), Gaps = 12/213 (5%)

Query: 468 DPEQDRCEASEQKQKVPLGTFRKDMKTQEEKQKQLTEKIRQQQEKLEALQKTTPIRSQAD 527
           +P     +++    K P  T  K   T  ++    T K        E    TTP +    
Sbjct: 428 EPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAP-TTPKKPAPT 486

Query: 528 LKKLPLEVTTRPSTEEPVRRPQRPRSPPLPAVIRNAPSRPPSLPTPRPASQPRKAPVISS 587
             K P   T +       ++P  P +P  PA      + P +     P +  + AP   +
Sbjct: 487 TPKEPAPTTPKEPAPTTTKKPA-PTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAP---T 542

Query: 588 TPKLPALAAREEASTSRLLQP-PEAPRKPANTLVKTASRPAPLVQQLSPSLLPNSKSPRE 646
           TP+ PA    EE + +   +P P  P +PA T  K A+   P     +    P   +P+E
Sbjct: 543 TPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKE 602

Query: 647 VPSPKVIK--TPVVKKTESPIKL---SPATPSR 674
            P+P   K   P   K  +P  L   +P TP +
Sbjct: 603 -PAPTTPKETAPTTPKGTAPTTLKEPAPTTPKK 634



 Score = 44.3 bits (103), Expect = 6e-04
 Identities = 51/214 (23%), Positives = 73/214 (34%), Gaps = 17/214 (7%)

Query: 475 EASEQKQKVPLGTFRKDMKTQEEKQKQLTEKIRQQQEKLEALQKTTPIRSQADLKKLPLE 534
           E +    K P  T  K+      K+   T   +      E L  TTP   +      P E
Sbjct: 498 EPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTP---EKPAPTTPEE 554

Query: 535 VTTRPSTEEPVRRPQRPRSPPLPAVIRNAPSRPPSLPTPRPASQPRKAPVISSTPKLPAL 594
           +      E     P+ P      A   N P  P       PA    K P   +TPK  A 
Sbjct: 555 LAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPA-PTTPKETAP 613

Query: 595 AAREEASTSRLLQP-PEAPRKP-----ANTLVK-----TASRPAPLVQQLSPSLLPNSKS 643
              +  + + L +P P  P+KP     A T  K     T  +PAP   + +    P   +
Sbjct: 614 TTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPA 673

Query: 644 PR--EVPSPKVIKTPVVKKTESPIKLSPATPSRK 675
           P   + P+P   K       + P   +P  P+ K
Sbjct: 674 PTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPK 707



 Score = 42.4 bits (98), Expect = 0.002
 Identities = 43/164 (26%), Positives = 62/164 (37%), Gaps = 21/164 (12%)

Query: 536 TTRPSTEEPVRRPQRPRSPPLPAVIRNAPSRPPSLPTPRPASQPRKAPV----------I 585
           TT   T     +   P +P  PA      + P +L  P P +  + AP            
Sbjct: 659 TTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPT 718

Query: 586 SSTPKLPALAAREEASTSRLLQP-PEAPRKPANTLVKTASRPAPLVQQLSPSLLPNS--- 641
           S+T   PA    +E + +   +P P  P+KPA T   T   P P   ++S          
Sbjct: 719 STTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPT---TPETPPPTTSEVSTPTTTKEPTT 775

Query: 642 --KSPREVPSPKVIKTPVVKKTESPIKLSPATPSRKRSVAVSDE 683
             KSP E  +P++   P  K  E+  K  P  P+ K   A   E
Sbjct: 776 IHKSPDE-STPELSAEPTPKALENSPK-EPGVPTTKTPAATKPE 817



 Score = 38.5 bits (88), Expect = 0.031
 Identities = 35/120 (29%), Positives = 55/120 (45%), Gaps = 24/120 (20%)

Query: 571 PTPRPASQPRKAPVISSTPKLPALAAREEASTSRLLQP--------PEAPRKPANTLVKT 622
           PTP+ A    K P ++ TPK P     +E +++   +P        P  P++PA T  K+
Sbjct: 238 PTPK-AETTTKGPALT-TPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKS 295

Query: 623 A----SRPAPLVQQLSPSLLPNSKSPREVPSPKVIKTPVVKKTES----PIKLSPATPSR 674
           A      PAP     + +  P   +P+E P+P   K P    T+S    P + +P TP +
Sbjct: 296 APTTPKEPAP-----TTTKEPAPTTPKE-PAPTTTKEPAPTTTKSAPTTPKEPAPTTPKK 349



 Score = 38.1 bits (87), Expect = 0.040
 Identities = 43/226 (19%), Positives = 82/226 (36%), Gaps = 18/226 (7%)

Query: 519 TTPIRSQADLKKLPLEVT--TRPSTEEPVRRPQRPRSPPLPAVIRNAPSRPPSL---PTP 573
           TTP        K P   T  T P T   V  P   + P    + ++     P L   PTP
Sbjct: 736 TTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPT--TIHKSPDESTPELSAEPTP 793

Query: 574 RPASQPRKAPVISSTPKLPALAAREEASTSRLLQPPEAPRKPANTLVKTASRPAPLVQQL 633
           +      K P + +T K PA    E  +T++     +   +   T  +T +    + ++ 
Sbjct: 794 KALENSPKEPGVPTT-KTPAATKPEMTTTAK----DKTTERDLRTTPETTTAAPKMTKET 848

Query: 634 SPSLLPNSKSPREVPSPKVIKTPVVKKTESPIK------LSPATPSRKRSVAVSDEEEVE 687
           + +    ++S     + +V  T     T   I       L+P   + K+++  ++     
Sbjct: 849 ATTTEKTTESKITATTTQVTSTTTQDTTPFKITTLKTTTLAPKVTTTKKTITTTEIMNKP 908

Query: 688 EEAERRKERCKRGRFVVKEEKKDSNELSDSAGEEDSADLKRAQKDK 733
           EE  + K+R    +    + +K +         +    + R +K K
Sbjct: 909 EETAKPKDRATNSKATTPKPQKPTKAPKKPTSTKKPKTMPRVRKPK 954



 Score = 37.0 bits (84), Expect = 0.090
 Identities = 48/220 (21%), Positives = 84/220 (38%), Gaps = 32/220 (14%)

Query: 458 PDTWVCSMNPDPEQDRCEASEQKQKVPLGTFRKDMKTQEEKQKQLTEKIRQQQEKLEALQ 517
           PD     ++ +P     E S ++  VP        KT    + ++T           A  
Sbjct: 780 PDESTPELSAEPTPKALENSPKEPGVPT------TKTPAATKPEMTTT---------AKD 824

Query: 518 KTTPIRSQADLKKLPLEVTTRPS-TEEPVRRPQRPRSPPLPAVIRNAPSRPPSLPTPRPA 576
           KTT    + DL+  P   T  P  T+E     ++     + A      S      T    
Sbjct: 825 KTT----ERDLRTTPETTTAAPKMTKETATTTEKTTESKITATTTQVTS------TTTQD 874

Query: 577 SQPRKAPVISSTPKLPALAAREEA-STSRLLQPPEAPRKPANTLVKT-ASRPAPLVQQLS 634
           + P K   + +T   P +   ++  +T+ ++  PE   KP +    + A+ P P     +
Sbjct: 875 TTPFKITTLKTTTLAPKVTTTKKTITTTEIMNKPEETAKPKDRATNSKATTPKPQKPTKA 934

Query: 635 PSLLPNSKSPREVP---SPKVIKTPVVKKTESPIKLSPAT 671
           P    ++K P+ +P    PK   TP  K T +  +L+P +
Sbjct: 935 PKKPTSTKKPKTMPRVRKPKTTPTP-RKMTSTMPELNPTS 973



 Score = 32.7 bits (73), Expect = 1.7
 Identities = 23/94 (24%), Positives = 37/94 (39%), Gaps = 4/94 (4%)

Query: 519 TTPIRSQADLKKLPLEVTTRPSTEEPVRRPQRPRSPPLPAVIRNAPSRPPSLPTPRPASQ 578
           TT I ++ +    P +  T      P  +PQ+P   P        P   P +  P+    
Sbjct: 901 TTEIMNKPEETAKPKDRATNSKATTP--KPQKPTKAPKKPTSTKKPKTMPRVRKPKTTPT 958

Query: 579 PRKAPVISSTPKLPALAAREEASTSRLLQPPEAP 612
           PRK  + S+ P+L   +   EA      +P + P
Sbjct: 959 PRK--MTSTMPELNPTSRIAEAMLQTTTRPNQTP 990


>gi|189181720 proteoglycan 4 isoform B [Homo sapiens]
          Length = 1363

 Score = 57.8 bits (138), Expect = 5e-08
 Identities = 55/185 (29%), Positives = 77/185 (41%), Gaps = 36/185 (19%)

Query: 520 TPIRSQADLKKLPLEVTTRPS-----------TEEPVRRPQRPRSP-------PLPAVIR 561
           T I+S     K P   TT+ +           T+EP   P  P+ P       P P   +
Sbjct: 328 TTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPA--PTTPKEPAPTTTKEPAPTTTK 385

Query: 562 NAPSRP-------PSLPTP----RPASQPRKAPVISSTPKLPALAAREEASTSRLLQPPE 610
           +AP+ P       P  P P     PA    K P   +TPK PA   +E A T+     P 
Sbjct: 386 SAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPT-PTTPKEPAPTTKEPAPTTPKEPAPT 444

Query: 611 APRKPANTLVKTASRPAPLVQQLSPSLLPNSKSPREVPSPKVIKT-PVVKKTESP--IKL 667
           AP+KPA T  K  +   P     + +  P+  +P+E P+P   K+ P   K  +P   K 
Sbjct: 445 APKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKE-PAPTTTKSAPTTTKEPAPTTTKS 503

Query: 668 SPATP 672
           +P TP
Sbjct: 504 APTTP 508



 Score = 56.2 bits (134), Expect = 1e-07
 Identities = 52/201 (25%), Positives = 76/201 (37%), Gaps = 24/201 (11%)

Query: 493 KTQEEKQKQLTEKIRQQQ--EKLEALQKTTPIRSQADLKKLPLEVTTRPSTEEPVRRPQR 550
           KT   K+ Q  EK   +      + L K TP +++   K   L     P+   P      
Sbjct: 262 KTTSAKETQSIEKTSAKDLAPTSKVLAKPTP-KAETTTKGPALTTPKEPTPTTPKEPAST 320

Query: 551 PRSPPLPAVIRNAPSRPP--------SLPT----PRPASQPRKAPVISSTPKLPALAARE 598
               P P  I++AP+ P         S PT    P P +    AP   +TPK PA    +
Sbjct: 321 TPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAP---TTPKEPAPTTTK 377

Query: 599 EASTSRLLQPPEAPRKPANTLVK-----TASRPAPLVQQLSPSLLPNSKSP-REVPSPKV 652
           E + +     P  P++PA T  K     T   PAP   +      P   +P  + P+P  
Sbjct: 378 EPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTT 437

Query: 653 IKTPVVKKTESPIKLSPATPS 673
            K P     + P   +P  P+
Sbjct: 438 PKEPAPTAPKKPAPTTPKEPA 458



 Score = 51.6 bits (122), Expect = 4e-06
 Identities = 44/171 (25%), Positives = 66/171 (38%), Gaps = 23/171 (13%)

Query: 519 TTPIRSQADLKKLPLEVTTR---PSTEEPVRRPQRPRSPPLPAVIRNAPSRP-------P 568
           TTP        K P   T +   P+T+EP   P  P+ P   A  + AP+ P       P
Sbjct: 405 TTPKEPAPTTPKEPTPTTPKEPAPTTKEPA--PTTPKEPAPTAPKKPAPTTPKEPAPTTP 462

Query: 569 SLPTPRPASQPR----KAPVISSTPKLPALAAREEASTSRLLQPPEAPRKPANTLVKTAS 624
             P P    +P     K P  ++T   P        +T++    P  P++P+ T   T  
Sbjct: 463 KEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTK--SAPTTPKEPSPT---TTK 517

Query: 625 RPAPLVQQLSPSLLPNSKSPR--EVPSPKVIKTPVVKKTESPIKLSPATPS 673
            PAP   +      P   +P   + P+P   K P    T+ P   +P  P+
Sbjct: 518 EPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPA 568



 Score = 49.7 bits (117), Expect = 1e-05
 Identities = 53/221 (23%), Positives = 76/221 (34%), Gaps = 23/221 (10%)

Query: 468 DPEQDRCEASEQKQKVPLGTFRKDMKTQEEKQKQLTEKIRQQQEKLEALQKTTPIRSQAD 527
           +P     +++    K P  T  K   T  ++    T K        E    TT   +   
Sbjct: 324 EPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTT 383

Query: 528 LKKLPLEVTTRPSTEEPVRRPQRPRSPPLPAVIRNAPSRP--PSLPTPRPASQPRKAPVI 585
            K  P        T      P  P+ P         P+ P  P+  T  PA    K P  
Sbjct: 384 TKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPA- 442

Query: 586 SSTPKLPALAA---------REEASTSRLLQPPEAPRKPANTLVK----TASRPAPLVQQ 632
            + PK PA            +E A T+     P  P++PA T  K    T   PAP   +
Sbjct: 443 PTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTK 502

Query: 633 LSPSLLPNSKSPREVPSPKVIKTPVVKKTESPIKLSPATPS 673
            +P+      +P+E PSP   K P     + P   +P  P+
Sbjct: 503 SAPT------TPKE-PSPTTTKEPAPTTPKEPAPTTPKKPA 536



 Score = 49.3 bits (116), Expect = 2e-05
 Identities = 44/160 (27%), Positives = 62/160 (38%), Gaps = 13/160 (8%)

Query: 519 TTPIRSQADLKKLPLEVTTRPSTEEPVRRPQRPRSPPLPAVIRNAPSRP--PSLPT---P 573
           TTP        K P   T +       +        P P   ++AP+ P  PS  T   P
Sbjct: 460 TTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEP 519

Query: 574 RPASQPRKAPVISSTPKLPALAAREEASTSRLLQP-PEAPRKPANTLVKTASRPAPLVQQ 632
            P +    AP   +TPK PA    +E + +   +P P   +KPA T   T   PAP   +
Sbjct: 520 APTTPKEPAP---TTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPT---TPKEPAPTTPK 573

Query: 633 LSPSLLPNSKSPREVPSPKVIKTPVVKKTESPIKLSPATP 672
            +    P   +P   P      TP      +P +L+P TP
Sbjct: 574 ETAPTTPKKLTP-TTPEKLAPTTPEKPAPTTPEELAPTTP 612



 Score = 47.0 bits (110), Expect = 9e-05
 Identities = 52/213 (24%), Positives = 81/213 (38%), Gaps = 12/213 (5%)

Query: 468 DPEQDRCEASEQKQKVPLGTFRKDMKTQEEKQKQLTEKIRQQQEKLEALQKTTPIRSQAD 527
           +P     +++    K P  T  K   T  ++    T K        E    TTP +    
Sbjct: 480 EPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAP-TTPKKPAPT 538

Query: 528 LKKLPLEVTTRPSTEEPVRRPQRPRSPPLPAVIRNAPSRPPSLPTPRPASQPRKAPVISS 587
             K P   T +       ++P  P +P  PA      + P +     P +  + AP   +
Sbjct: 539 TPKEPAPTTPKEPAPTTTKKPA-PTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAP---T 594

Query: 588 TPKLPALAAREEASTSRLLQP-PEAPRKPANTLVKTASRPAPLVQQLSPSLLPNSKSPRE 646
           TP+ PA    EE + +   +P P  P +PA T  K A+   P     +    P   +P+E
Sbjct: 595 TPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKE 654

Query: 647 VPSPKVIK--TPVVKKTESPIKL---SPATPSR 674
            P+P   K   P   K  +P  L   +P TP +
Sbjct: 655 -PAPTTPKETAPTTPKGTAPTTLKEPAPTTPKK 686



 Score = 44.3 bits (103), Expect = 6e-04
 Identities = 51/214 (23%), Positives = 73/214 (34%), Gaps = 17/214 (7%)

Query: 475 EASEQKQKVPLGTFRKDMKTQEEKQKQLTEKIRQQQEKLEALQKTTPIRSQADLKKLPLE 534
           E +    K P  T  K+      K+   T   +      E L  TTP   +      P E
Sbjct: 550 EPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTP---EKPAPTTPEE 606

Query: 535 VTTRPSTEEPVRRPQRPRSPPLPAVIRNAPSRPPSLPTPRPASQPRKAPVISSTPKLPAL 594
           +      E     P+ P      A   N P  P       PA    K P   +TPK  A 
Sbjct: 607 LAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPA-PTTPKETAP 665

Query: 595 AAREEASTSRLLQP-PEAPRKP-----ANTLVK-----TASRPAPLVQQLSPSLLPNSKS 643
              +  + + L +P P  P+KP     A T  K     T  +PAP   + +    P   +
Sbjct: 666 TTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPA 725

Query: 644 PR--EVPSPKVIKTPVVKKTESPIKLSPATPSRK 675
           P   + P+P   K       + P   +P  P+ K
Sbjct: 726 PTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPK 759



 Score = 42.4 bits (98), Expect = 0.002
 Identities = 43/164 (26%), Positives = 62/164 (37%), Gaps = 21/164 (12%)

Query: 536 TTRPSTEEPVRRPQRPRSPPLPAVIRNAPSRPPSLPTPRPASQPRKAPV----------I 585
           TT   T     +   P +P  PA      + P +L  P P +  + AP            
Sbjct: 711 TTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPT 770

Query: 586 SSTPKLPALAAREEASTSRLLQP-PEAPRKPANTLVKTASRPAPLVQQLSPSLLPNS--- 641
           S+T   PA    +E + +   +P P  P+KPA T   T   P P   ++S          
Sbjct: 771 STTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPT---TPETPPPTTSEVSTPTTTKEPTT 827

Query: 642 --KSPREVPSPKVIKTPVVKKTESPIKLSPATPSRKRSVAVSDE 683
             KSP E  +P++   P  K  E+  K  P  P+ K   A   E
Sbjct: 828 IHKSPDE-STPELSAEPTPKALENSPK-EPGVPTTKTPAATKPE 869



 Score = 38.5 bits (88), Expect = 0.031
 Identities = 35/120 (29%), Positives = 55/120 (45%), Gaps = 24/120 (20%)

Query: 571 PTPRPASQPRKAPVISSTPKLPALAAREEASTSRLLQP--------PEAPRKPANTLVKT 622
           PTP+ A    K P ++ TPK P     +E +++   +P        P  P++PA T  K+
Sbjct: 290 PTPK-AETTTKGPALT-TPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKS 347

Query: 623 A----SRPAPLVQQLSPSLLPNSKSPREVPSPKVIKTPVVKKTES----PIKLSPATPSR 674
           A      PAP     + +  P   +P+E P+P   K P    T+S    P + +P TP +
Sbjct: 348 APTTPKEPAP-----TTTKEPAPTTPKE-PAPTTTKEPAPTTTKSAPTTPKEPAPTTPKK 401



 Score = 38.1 bits (87), Expect = 0.040
 Identities = 43/226 (19%), Positives = 82/226 (36%), Gaps = 18/226 (7%)

Query: 519  TTPIRSQADLKKLPLEVT--TRPSTEEPVRRPQRPRSPPLPAVIRNAPSRPPSL---PTP 573
            TTP        K P   T  T P T   V  P   + P    + ++     P L   PTP
Sbjct: 788  TTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPT--TIHKSPDESTPELSAEPTP 845

Query: 574  RPASQPRKAPVISSTPKLPALAAREEASTSRLLQPPEAPRKPANTLVKTASRPAPLVQQL 633
            +      K P + +T K PA    E  +T++     +   +   T  +T +    + ++ 
Sbjct: 846  KALENSPKEPGVPTT-KTPAATKPEMTTTAK----DKTTERDLRTTPETTTAAPKMTKET 900

Query: 634  SPSLLPNSKSPREVPSPKVIKTPVVKKTESPIK------LSPATPSRKRSVAVSDEEEVE 687
            + +    ++S     + +V  T     T   I       L+P   + K+++  ++     
Sbjct: 901  ATTTEKTTESKITATTTQVTSTTTQDTTPFKITTLKTTTLAPKVTTTKKTITTTEIMNKP 960

Query: 688  EEAERRKERCKRGRFVVKEEKKDSNELSDSAGEEDSADLKRAQKDK 733
            EE  + K+R    +    + +K +         +    + R +K K
Sbjct: 961  EETAKPKDRATNSKATTPKPQKPTKAPKKPTSTKKPKTMPRVRKPK 1006



 Score = 37.0 bits (84), Expect = 0.090
 Identities = 48/220 (21%), Positives = 84/220 (38%), Gaps = 32/220 (14%)

Query: 458  PDTWVCSMNPDPEQDRCEASEQKQKVPLGTFRKDMKTQEEKQKQLTEKIRQQQEKLEALQ 517
            PD     ++ +P     E S ++  VP        KT    + ++T           A  
Sbjct: 832  PDESTPELSAEPTPKALENSPKEPGVPT------TKTPAATKPEMTTT---------AKD 876

Query: 518  KTTPIRSQADLKKLPLEVTTRPS-TEEPVRRPQRPRSPPLPAVIRNAPSRPPSLPTPRPA 576
            KTT    + DL+  P   T  P  T+E     ++     + A      S      T    
Sbjct: 877  KTT----ERDLRTTPETTTAAPKMTKETATTTEKTTESKITATTTQVTS------TTTQD 926

Query: 577  SQPRKAPVISSTPKLPALAAREEA-STSRLLQPPEAPRKPANTLVKT-ASRPAPLVQQLS 634
            + P K   + +T   P +   ++  +T+ ++  PE   KP +    + A+ P P     +
Sbjct: 927  TTPFKITTLKTTTLAPKVTTTKKTITTTEIMNKPEETAKPKDRATNSKATTPKPQKPTKA 986

Query: 635  PSLLPNSKSPREVP---SPKVIKTPVVKKTESPIKLSPAT 671
            P    ++K P+ +P    PK   TP  K T +  +L+P +
Sbjct: 987  PKKPTSTKKPKTMPRVRKPKTTPTP-RKMTSTMPELNPTS 1025



 Score = 32.7 bits (73), Expect = 1.7
 Identities = 23/94 (24%), Positives = 37/94 (39%), Gaps = 4/94 (4%)

Query: 519  TTPIRSQADLKKLPLEVTTRPSTEEPVRRPQRPRSPPLPAVIRNAPSRPPSLPTPRPASQ 578
            TT I ++ +    P +  T      P  +PQ+P   P        P   P +  P+    
Sbjct: 953  TTEIMNKPEETAKPKDRATNSKATTP--KPQKPTKAPKKPTSTKKPKTMPRVRKPKTTPT 1010

Query: 579  PRKAPVISSTPKLPALAAREEASTSRLLQPPEAP 612
            PRK  + S+ P+L   +   EA      +P + P
Sbjct: 1011 PRK--MTSTMPELNPTSRIAEAMLQTTTRPNQTP 1042


>gi|67190163 proteoglycan 4 isoform A [Homo sapiens]
          Length = 1404

 Score = 57.8 bits (138), Expect = 5e-08
 Identities = 55/185 (29%), Positives = 77/185 (41%), Gaps = 36/185 (19%)

Query: 520 TPIRSQADLKKLPLEVTTRPS-----------TEEPVRRPQRPRSP-------PLPAVIR 561
           T I+S     K P   TT+ +           T+EP   P  P+ P       P P   +
Sbjct: 369 TTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPA--PTTPKEPAPTTTKEPAPTTTK 426

Query: 562 NAPSRP-------PSLPTP----RPASQPRKAPVISSTPKLPALAAREEASTSRLLQPPE 610
           +AP+ P       P  P P     PA    K P   +TPK PA   +E A T+     P 
Sbjct: 427 SAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPT-PTTPKEPAPTTKEPAPTTPKEPAPT 485

Query: 611 APRKPANTLVKTASRPAPLVQQLSPSLLPNSKSPREVPSPKVIKT-PVVKKTESP--IKL 667
           AP+KPA T  K  +   P     + +  P+  +P+E P+P   K+ P   K  +P   K 
Sbjct: 486 APKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKE-PAPTTTKSAPTTTKEPAPTTTKS 544

Query: 668 SPATP 672
           +P TP
Sbjct: 545 APTTP 549



 Score = 56.2 bits (134), Expect = 1e-07
 Identities = 52/201 (25%), Positives = 76/201 (37%), Gaps = 24/201 (11%)

Query: 493 KTQEEKQKQLTEKIRQQQ--EKLEALQKTTPIRSQADLKKLPLEVTTRPSTEEPVRRPQR 550
           KT   K+ Q  EK   +      + L K TP +++   K   L     P+   P      
Sbjct: 303 KTTSAKETQSIEKTSAKDLAPTSKVLAKPTP-KAETTTKGPALTTPKEPTPTTPKEPAST 361

Query: 551 PRSPPLPAVIRNAPSRPP--------SLPT----PRPASQPRKAPVISSTPKLPALAARE 598
               P P  I++AP+ P         S PT    P P +    AP   +TPK PA    +
Sbjct: 362 TPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAP---TTPKEPAPTTTK 418

Query: 599 EASTSRLLQPPEAPRKPANTLVK-----TASRPAPLVQQLSPSLLPNSKSP-REVPSPKV 652
           E + +     P  P++PA T  K     T   PAP   +      P   +P  + P+P  
Sbjct: 419 EPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTT 478

Query: 653 IKTPVVKKTESPIKLSPATPS 673
            K P     + P   +P  P+
Sbjct: 479 PKEPAPTAPKKPAPTTPKEPA 499



 Score = 51.6 bits (122), Expect = 4e-06
 Identities = 44/171 (25%), Positives = 66/171 (38%), Gaps = 23/171 (13%)

Query: 519 TTPIRSQADLKKLPLEVTTR---PSTEEPVRRPQRPRSPPLPAVIRNAPSRP-------P 568
           TTP        K P   T +   P+T+EP   P  P+ P   A  + AP+ P       P
Sbjct: 446 TTPKEPAPTTPKEPTPTTPKEPAPTTKEPA--PTTPKEPAPTAPKKPAPTTPKEPAPTTP 503

Query: 569 SLPTPRPASQPR----KAPVISSTPKLPALAAREEASTSRLLQPPEAPRKPANTLVKTAS 624
             P P    +P     K P  ++T   P        +T++    P  P++P+ T   T  
Sbjct: 504 KEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTK--SAPTTPKEPSPT---TTK 558

Query: 625 RPAPLVQQLSPSLLPNSKSPR--EVPSPKVIKTPVVKKTESPIKLSPATPS 673
            PAP   +      P   +P   + P+P   K P    T+ P   +P  P+
Sbjct: 559 EPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPA 609



 Score = 49.7 bits (117), Expect = 1e-05
 Identities = 53/221 (23%), Positives = 76/221 (34%), Gaps = 23/221 (10%)

Query: 468 DPEQDRCEASEQKQKVPLGTFRKDMKTQEEKQKQLTEKIRQQQEKLEALQKTTPIRSQAD 527
           +P     +++    K P  T  K   T  ++    T K        E    TT   +   
Sbjct: 365 EPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTT 424

Query: 528 LKKLPLEVTTRPSTEEPVRRPQRPRSPPLPAVIRNAPSRP--PSLPTPRPASQPRKAPVI 585
            K  P        T      P  P+ P         P+ P  P+  T  PA    K P  
Sbjct: 425 TKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPA- 483

Query: 586 SSTPKLPALAA---------REEASTSRLLQPPEAPRKPANTLVK----TASRPAPLVQQ 632
            + PK PA            +E A T+     P  P++PA T  K    T   PAP   +
Sbjct: 484 PTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTK 543

Query: 633 LSPSLLPNSKSPREVPSPKVIKTPVVKKTESPIKLSPATPS 673
            +P+      +P+E PSP   K P     + P   +P  P+
Sbjct: 544 SAPT------TPKE-PSPTTTKEPAPTTPKEPAPTTPKKPA 577



 Score = 49.3 bits (116), Expect = 2e-05
 Identities = 44/160 (27%), Positives = 62/160 (38%), Gaps = 13/160 (8%)

Query: 519 TTPIRSQADLKKLPLEVTTRPSTEEPVRRPQRPRSPPLPAVIRNAPSRP--PSLPT---P 573
           TTP        K P   T +       +        P P   ++AP+ P  PS  T   P
Sbjct: 501 TTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEP 560

Query: 574 RPASQPRKAPVISSTPKLPALAAREEASTSRLLQP-PEAPRKPANTLVKTASRPAPLVQQ 632
            P +    AP   +TPK PA    +E + +   +P P   +KPA T   T   PAP   +
Sbjct: 561 APTTPKEPAP---TTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPT---TPKEPAPTTPK 614

Query: 633 LSPSLLPNSKSPREVPSPKVIKTPVVKKTESPIKLSPATP 672
            +    P   +P   P      TP      +P +L+P TP
Sbjct: 615 ETAPTTPKKLTP-TTPEKLAPTTPEKPAPTTPEELAPTTP 653



 Score = 47.0 bits (110), Expect = 9e-05
 Identities = 52/213 (24%), Positives = 81/213 (38%), Gaps = 12/213 (5%)

Query: 468 DPEQDRCEASEQKQKVPLGTFRKDMKTQEEKQKQLTEKIRQQQEKLEALQKTTPIRSQAD 527
           +P     +++    K P  T  K   T  ++    T K        E    TTP +    
Sbjct: 521 EPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAP-TTPKKPAPT 579

Query: 528 LKKLPLEVTTRPSTEEPVRRPQRPRSPPLPAVIRNAPSRPPSLPTPRPASQPRKAPVISS 587
             K P   T +       ++P  P +P  PA      + P +     P +  + AP   +
Sbjct: 580 TPKEPAPTTPKEPAPTTTKKPA-PTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAP---T 635

Query: 588 TPKLPALAAREEASTSRLLQP-PEAPRKPANTLVKTASRPAPLVQQLSPSLLPNSKSPRE 646
           TP+ PA    EE + +   +P P  P +PA T  K A+   P     +    P   +P+E
Sbjct: 636 TPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKE 695

Query: 647 VPSPKVIK--TPVVKKTESPIKL---SPATPSR 674
            P+P   K   P   K  +P  L   +P TP +
Sbjct: 696 -PAPTTPKETAPTTPKGTAPTTLKEPAPTTPKK 727



 Score = 44.3 bits (103), Expect = 6e-04
 Identities = 51/214 (23%), Positives = 73/214 (34%), Gaps = 17/214 (7%)

Query: 475 EASEQKQKVPLGTFRKDMKTQEEKQKQLTEKIRQQQEKLEALQKTTPIRSQADLKKLPLE 534
           E +    K P  T  K+      K+   T   +      E L  TTP   +      P E
Sbjct: 591 EPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTP---EKPAPTTPEE 647

Query: 535 VTTRPSTEEPVRRPQRPRSPPLPAVIRNAPSRPPSLPTPRPASQPRKAPVISSTPKLPAL 594
           +      E     P+ P      A   N P  P       PA    K P   +TPK  A 
Sbjct: 648 LAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPA-PTTPKETAP 706

Query: 595 AAREEASTSRLLQP-PEAPRKP-----ANTLVK-----TASRPAPLVQQLSPSLLPNSKS 643
              +  + + L +P P  P+KP     A T  K     T  +PAP   + +    P   +
Sbjct: 707 TTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPA 766

Query: 644 PR--EVPSPKVIKTPVVKKTESPIKLSPATPSRK 675
           P   + P+P   K       + P   +P  P+ K
Sbjct: 767 PTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPK 800



 Score = 42.4 bits (98), Expect = 0.002
 Identities = 43/164 (26%), Positives = 62/164 (37%), Gaps = 21/164 (12%)

Query: 536 TTRPSTEEPVRRPQRPRSPPLPAVIRNAPSRPPSLPTPRPASQPRKAPV----------I 585
           TT   T     +   P +P  PA      + P +L  P P +  + AP            
Sbjct: 752 TTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPT 811

Query: 586 SSTPKLPALAAREEASTSRLLQP-PEAPRKPANTLVKTASRPAPLVQQLSPSLLPNS--- 641
           S+T   PA    +E + +   +P P  P+KPA T   T   P P   ++S          
Sbjct: 812 STTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPT---TPETPPPTTSEVSTPTTTKEPTT 868

Query: 642 --KSPREVPSPKVIKTPVVKKTESPIKLSPATPSRKRSVAVSDE 683
             KSP E  +P++   P  K  E+  K  P  P+ K   A   E
Sbjct: 869 IHKSPDE-STPELSAEPTPKALENSPK-EPGVPTTKTPAATKPE 910



 Score = 38.5 bits (88), Expect = 0.031
 Identities = 35/120 (29%), Positives = 55/120 (45%), Gaps = 24/120 (20%)

Query: 571 PTPRPASQPRKAPVISSTPKLPALAAREEASTSRLLQP--------PEAPRKPANTLVKT 622
           PTP+ A    K P ++ TPK P     +E +++   +P        P  P++PA T  K+
Sbjct: 331 PTPK-AETTTKGPALT-TPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKS 388

Query: 623 A----SRPAPLVQQLSPSLLPNSKSPREVPSPKVIKTPVVKKTES----PIKLSPATPSR 674
           A      PAP     + +  P   +P+E P+P   K P    T+S    P + +P TP +
Sbjct: 389 APTTPKEPAP-----TTTKEPAPTTPKE-PAPTTTKEPAPTTTKSAPTTPKEPAPTTPKK 442



 Score = 38.1 bits (87), Expect = 0.040
 Identities = 43/226 (19%), Positives = 82/226 (36%), Gaps = 18/226 (7%)

Query: 519  TTPIRSQADLKKLPLEVT--TRPSTEEPVRRPQRPRSPPLPAVIRNAPSRPPSL---PTP 573
            TTP        K P   T  T P T   V  P   + P    + ++     P L   PTP
Sbjct: 829  TTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPT--TIHKSPDESTPELSAEPTP 886

Query: 574  RPASQPRKAPVISSTPKLPALAAREEASTSRLLQPPEAPRKPANTLVKTASRPAPLVQQL 633
            +      K P + +T K PA    E  +T++     +   +   T  +T +    + ++ 
Sbjct: 887  KALENSPKEPGVPTT-KTPAATKPEMTTTAK----DKTTERDLRTTPETTTAAPKMTKET 941

Query: 634  SPSLLPNSKSPREVPSPKVIKTPVVKKTESPIK------LSPATPSRKRSVAVSDEEEVE 687
            + +    ++S     + +V  T     T   I       L+P   + K+++  ++     
Sbjct: 942  ATTTEKTTESKITATTTQVTSTTTQDTTPFKITTLKTTTLAPKVTTTKKTITTTEIMNKP 1001

Query: 688  EEAERRKERCKRGRFVVKEEKKDSNELSDSAGEEDSADLKRAQKDK 733
            EE  + K+R    +    + +K +         +    + R +K K
Sbjct: 1002 EETAKPKDRATNSKATTPKPQKPTKAPKKPTSTKKPKTMPRVRKPK 1047



 Score = 37.0 bits (84), Expect = 0.090
 Identities = 48/220 (21%), Positives = 84/220 (38%), Gaps = 32/220 (14%)

Query: 458  PDTWVCSMNPDPEQDRCEASEQKQKVPLGTFRKDMKTQEEKQKQLTEKIRQQQEKLEALQ 517
            PD     ++ +P     E S ++  VP        KT    + ++T           A  
Sbjct: 873  PDESTPELSAEPTPKALENSPKEPGVPT------TKTPAATKPEMTTT---------AKD 917

Query: 518  KTTPIRSQADLKKLPLEVTTRPS-TEEPVRRPQRPRSPPLPAVIRNAPSRPPSLPTPRPA 576
            KTT    + DL+  P   T  P  T+E     ++     + A      S      T    
Sbjct: 918  KTT----ERDLRTTPETTTAAPKMTKETATTTEKTTESKITATTTQVTS------TTTQD 967

Query: 577  SQPRKAPVISSTPKLPALAAREEA-STSRLLQPPEAPRKPANTLVKT-ASRPAPLVQQLS 634
            + P K   + +T   P +   ++  +T+ ++  PE   KP +    + A+ P P     +
Sbjct: 968  TTPFKITTLKTTTLAPKVTTTKKTITTTEIMNKPEETAKPKDRATNSKATTPKPQKPTKA 1027

Query: 635  PSLLPNSKSPREVP---SPKVIKTPVVKKTESPIKLSPAT 671
            P    ++K P+ +P    PK   TP  K T +  +L+P +
Sbjct: 1028 PKKPTSTKKPKTMPRVRKPKTTPTP-RKMTSTMPELNPTS 1066



 Score = 32.7 bits (73), Expect = 1.7
 Identities = 23/94 (24%), Positives = 37/94 (39%), Gaps = 4/94 (4%)

Query: 519  TTPIRSQADLKKLPLEVTTRPSTEEPVRRPQRPRSPPLPAVIRNAPSRPPSLPTPRPASQ 578
            TT I ++ +    P +  T      P  +PQ+P   P        P   P +  P+    
Sbjct: 994  TTEIMNKPEETAKPKDRATNSKATTP--KPQKPTKAPKKPTSTKKPKTMPRVRKPKTTPT 1051

Query: 579  PRKAPVISSTPKLPALAAREEASTSRLLQPPEAP 612
            PRK  + S+ P+L   +   EA      +P + P
Sbjct: 1052 PRK--MTSTMPELNPTSRIAEAMLQTTTRPNQTP 1083


>gi|9945318 MAX binding protein [Homo sapiens]
          Length = 582

 Score = 51.6 bits (122), Expect = 4e-06
 Identities = 77/344 (22%), Positives = 129/344 (37%), Gaps = 28/344 (8%)

Query: 489 RKDMKTQEEKQKQLTEKIRQQQEK----LEALQKTTPIRS-QADLKKLPLEVTTRPSTEE 543
           ++  + +EE+++   E+ R+Q++K    L  L  T P+   + +   LPL     P    
Sbjct: 18  QQQQRAREEQERLRLEQEREQEQKKANSLARLAHTLPVEEPRMEAPPLPLSPPAPPPAPP 77

Query: 544 PVRRPQRPRSP-PLPAVIRNAPSRPPSLPTPRPASQPRKAPVISSTPKLPALAAREEAS- 601
           P      P +  P+P V  +    PP  P P  A     AP   +    P L+ +E A  
Sbjct: 78  PPLATPAPLTVIPIPVVTNSPQPLPPPPPLPAAAQPLPLAPRQPALVGAPGLSIKEPAPL 137

Query: 602 TSRLLQPPEAPRKP-ANTLVKTASRPAPLVQQLSPSLLPNSKSPREVPSPKVIKTPVVKK 660
            SR   P  AP  P +   +     P PL    +P L   + +P     P++        
Sbjct: 138 PSRPQVPTPAPLLPDSKATIPPNGSPKPLQPLPTPVL---TIAPHPGVQPQLAPQQPPPP 194

Query: 661 TESPIKLSPA-----TPSRKRSVAVSDEEEVEEEAERRKERCKRGRFVVK------EEKK 709
           T   +KL+PA     +  +KR   +   E   +  + R+   K     +K      ++KK
Sbjct: 195 TLGTLKLAPAEEVKSSEQKKRPGGIGTREVHNKLEKNRRAHLKECFETLKRNIPNVDDKK 254

Query: 710 DSNELSDSAGEEDSADLKRAQKDKGLHVEVRVNREWYTGRVTAVEVGKHVVRWKVKFDYV 769
            SN             LKR +K+    +E R+ RE    +    E+   + +W    D +
Sbjct: 255 TSNLSVLRTALRYIQSLKRKEKEYEHEME-RLAREKIATQQRLAELKHELSQW---MDVL 310

Query: 770 PTDTTPRDRWVEKGSEDVRLMKPPSPEHQSLDTQQEGGEEEVGP 813
             D   R     +  +D       S    ++D   E     +GP
Sbjct: 311 EIDRVLRQ--TGQPEDDQASTSTASEGEDNIDEDMEEDRAGLGP 352



 Score = 31.6 bits (70), Expect = 3.8
 Identities = 46/219 (21%), Positives = 74/219 (33%), Gaps = 40/219 (18%)

Query: 489 RKDMKTQEEKQKQLTEKIRQQQEKLEALQKTTPIRSQADLKKLPLEVTTRPSTEEPVRR- 547
           RK+ + + E ++   EKI  QQ   E   + +      ++ ++ L  T +P  ++     
Sbjct: 273 RKEKEYEHEMERLAREKIATQQRLAELKHELSQWMDVLEIDRV-LRQTGQPEDDQASTST 331

Query: 548 --------------------PQRPRSPPLPAVIRNAPSRPPSLPTPRPAS-QPRKAPVIS 586
                               P +    P P ++++    P + P P P    P    V  
Sbjct: 332 ASEGEDNIDEDMEEDRAGLGPPKLSHRPQPELLKSTLPPPSTTPAPLPPHPHPHPHSVAL 391

Query: 587 STPKLPALAAREEASTSRLLQPPEAPRKPANTLVKTASRPAPLVQQLS------------ 634
               LP    + +  T  L  PP  P  PA TLV     PA LV                
Sbjct: 392 PPAHLPVQQQQPQQKTP-LPAPPPPPAAPAQTLVPA---PAHLVATAGGGSTVIAHTATT 447

Query: 635 -PSLLPNSKSPREVPSPKVIKTPVVKKTESPIKLSPATP 672
             S++       + P  K I           ++L+PATP
Sbjct: 448 HASVIQTVNHVLQGPGGKHIAHIAPSAPSPAVQLAPATP 486


>gi|149158690 HLA-B associated transcript-2 [Homo sapiens]
          Length = 2157

 Score = 51.2 bits (121), Expect = 5e-06
 Identities = 59/215 (27%), Positives = 83/215 (38%), Gaps = 33/215 (15%)

Query: 456 DYPDTWVCSMNPDPEQDRCEASEQKQK-----VPLGTFRKDMKTQEEKQKQLTEKIRQQQ 510
           DYPD       P   +D  EA  Q++K     + L   R   + +EE+++   E+     
Sbjct: 428 DYPDRGGPPCKPPAPEDEDEAWRQRRKQSSSEISLAVERARRRREEEERRMQEERRAACA 487

Query: 511 EKLEALQKTTPIRSQADLKKLPLEVTTRPSTEEPVRRPQRPRSPPLPAVIRNAPSRPPSL 570
           EKL+ L +    +  A  K+L  E    P+       P  P  PP       AP  PP  
Sbjct: 488 EKLKRLDE----KFGAPDKRLKAEPAAPPAA------PSTPAPPPAVPKELPAPPAPPPA 537

Query: 571 PTPRPASQPR---KAPVISSTPKLPALAAREEASTSRLLQPPEAPRKPANTLVKTASRPA 627
             P P ++P    +AP   STP  P +AA           P       + +   + S  A
Sbjct: 538 SAPTPETEPEEPAQAPPAQSTP-TPGVAA----------APTLVSGGGSTSSTSSGSFEA 586

Query: 628 PLVQQLSPSLLPNSKSPREVPSPKVIKTPVVKKTE 662
             V+   PS     + P EVP P    TP V K E
Sbjct: 587 SPVEPQLPS-KEGPEPPEEVPPP---TTPPVPKVE 617


>gi|24431935 reticulon 4 isoform A [Homo sapiens]
          Length = 1192

 Score = 50.8 bits (120), Expect = 6e-06
 Identities = 84/367 (22%), Positives = 139/367 (37%), Gaps = 66/367 (17%)

Query: 488 FRKDMKTQEEKQKQLTEKIRQQQEKLEALQKTTPIRSQADLKKLPLEVTTRPSTEEPVRR 547
           F ++ + +EE++++  E   +  E+LE L++    +  A L   P  V T P+   P+  
Sbjct: 27  FVREPEDEEEEEEEEEEDEDEDLEELEVLER----KPAAGLSAAP--VPTAPAAGAPLMD 80

Query: 548 PQRPRSPPLPAVIRNAPSRPPSLPTPRPASQPRKAPVISSTPKLPALAAREEASTSRLLQ 607
                 PP P      P+ PP  P  +P+  P     +SST   P+  +    S S+L +
Sbjct: 81  FGNDFVPPAPR--GPLPAAPPVAPERQPSWDPSP---VSSTVPAPSPLSAAAVSPSKLPE 135

Query: 608 PPEAPRKPANTLVKTASRPAPLVQQLSPSLLPNSKSPREVPSPKVIKTPVVKKTESPIKL 667
             E P +P          PA +  Q  P   P + +P   PS                  
Sbjct: 136 DDEPPARPP------PPPPASVSPQAEPVWTPPAPAPAAPPS------------------ 171

Query: 668 SPATPSRKRSVAVSDEEEVEEEAERRKE-RCKRGRFVVKEEKKDSNELSDSAGEED--SA 724
           +PA P R+ S    DE      A      R       +KE+  ++     SAG+ED  S 
Sbjct: 172 TPAAPKRRGSSGSVDETLFALPAASEPVIRSSAENMDLKEQPGNTI----SAGQEDFPSV 227

Query: 725 DLKRAQKDKGLHV--EVRVNREWYTGRVTAVEVGKHVVRWKVKFDYVPTDTTPRDRWVEK 782
            L+ A     L            Y G ++ V               +PT+ T ++  V +
Sbjct: 228 LLETAASLPSLSPLSAASFKEHEYLGNLSTV---------------LPTEGTLQEN-VSE 271

Query: 783 GSEDVR------LMKPPSPEHQSLDTQQEGGEEEVGPVAQQAIAVAEPSTSECLRIEPDT 836
            S++V       L+     E   L+  + G    V P A+ A+ VA P     ++ + + 
Sbjct: 272 ASKEVSEKAKTLLIDRDLTEFSELEYSEMGSSFSVSPKAESAVIVANPREEIIVKNKDEE 331

Query: 837 TALSTNH 843
             L +N+
Sbjct: 332 EKLVSNN 338


>gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens]
          Length = 904

 Score = 50.4 bits (119), Expect = 8e-06
 Identities = 69/290 (23%), Positives = 116/290 (40%), Gaps = 52/290 (17%)

Query: 468 DPEQDRCEASEQKQKVPLGTFRKDMKTQEEKQKQLTEKIRQQQEKLEALQKTTPIRSQAD 527
           +P      ++    KVP     K     E K+    +  ++++EK    +KT P RS++ 
Sbjct: 232 EPSVQEATSTSDILKVP-----KPEPIPEPKEPSPEKNSKKEKEK----EKTRP-RSRSR 281

Query: 528 LKKLPLEVTTRPSTEEPVRRPQR------PRSPPLPAVIRNAPSR--PPSLPTPRPASQP 579
            K      +  PS   P RR +       PR  P P   R +P R  PP    P P  + 
Sbjct: 282 SKSRSRTRSRSPSHTRPRRRHRSRSRSYSPRRRPSPRR-RPSPRRRTPPRRMPPPPRHRR 340

Query: 580 RKAPVISSTPKLPALAAREEASTSRLLQPPEAPRKPANTLVKTASRPAPLVQQLSPSLLP 639
            ++PV        +L+    +S+S   + P  P+KP     K  S P    ++LSPS  P
Sbjct: 341 SRSPVRRRRRSSASLSGSSSSSSSSRSRSP--PKKPP----KRTSSPPRKTRRLSPSASP 394

Query: 640 NSK----SPREVPSPKVIKTPVVKKT----ESPIKLSPATPSRK---------------- 675
             +    SP   P PK   +P  +++    +S + +SP   S K                
Sbjct: 395 PRRRHRPSPPATPPPKTRHSPTPQQSNRTRKSRVSVSPGRTSGKVTKHKGTEKRESPSPA 454

Query: 676 ---RSVAVSDEEEVEEEAERRKERCKRGRFVVKEEKKDSNELSDSAGEED 722
              R V +S+ EE +       +  ++ R   ++ ++ S++   S+  ED
Sbjct: 455 PKPRKVELSESEEDKGGKMAAADSVQQRRQYRRQNQQSSSDSGSSSSSED 504



 Score = 45.4 bits (106), Expect = 3e-04
 Identities = 51/158 (32%), Positives = 71/158 (44%), Gaps = 23/158 (14%)

Query: 544 PVRRPQRPRS-PPLPAVIRNAPSRPPS-----LPTPRPASQP---RKAPVISSTPK---L 591
           P   P+R  + PP P   R +PS PP       P P+  S P   R++P +SS  +    
Sbjct: 606 PSPPPKRRTASPPPPPKRRASPSPPPKRRVSHSPPPKQRSSPVTKRRSPSLSSKHRKGSS 665

Query: 592 PALAAREEAS--TSRLLQPPEAPRKPANTLVKTASRPAPLVQQLSPS-LLPNSKSPREVP 648
           P+ + RE  S   ++   P   PR P     +T+S P P+ +  S S     S SP   P
Sbjct: 666 PSRSTREARSPQPNKRHSPSPRPRAP-----QTSSSPPPVRRGASSSPQRRQSPSPSTRP 720

Query: 649 SPKVIKTP---VVKKTESPIKLSPATPSRKRSVAVSDE 683
             +V +TP    +KK  SP   S    S  RSV+ S E
Sbjct: 721 IRRVSRTPEPKKIKKAASPSPQSVRRVSSSRSVSGSPE 758



 Score = 44.7 bits (104), Expect = 4e-04
 Identities = 56/219 (25%), Positives = 80/219 (36%), Gaps = 23/219 (10%)

Query: 466 NPDPEQDRCEASEQKQKVPLGTFRKDMKTQEEKQKQLTEKIRQQQEKLEALQKTTPIRSQ 525
           N     D   +S  + + P    R  +K  E  +++     R         QK T  R +
Sbjct: 489 NQQSSSDSGSSSSSEDERPK---RSHVKNGEVGRRRRHSPSRSASPSPRKRQKETSPRGR 545

Query: 526 ADLKKLPLEVTTR--PSTEEPVRRPQRPRSPPLPAVIRNAPSRPP--SLPTPRPASQPRK 581
                 P     R  PS   P RR + P  PP     R  PS PP    P+PR  S P +
Sbjct: 546 RRRSPSPPPTRRRRSPSPAPPPRRRRTPTPPPR----RRTPSPPPRRRSPSPRRYSPPIQ 601

Query: 582 APVISSTPKLPALAAREEASTSRLLQPPEAPRKPANTLVKTASRPAPLVQQLSPSLLPN- 640
               S +P      A       R   P   P++  +       R +P+ ++ SPSL    
Sbjct: 602 RR-YSPSPPPKRRTASPPPPPKRRASPSPPPKRRVSHSPPPKQRSSPVTKRRSPSLSSKH 660

Query: 641 ------SKSPREVPSPKVIKTPVVKKTESPIKLSPATPS 673
                 S+S RE  SP+    P  + + SP   +P T S
Sbjct: 661 RKGSSPSRSTREARSPQ----PNKRHSPSPRPRAPQTSS 695



 Score = 43.1 bits (100), Expect = 0.001
 Identities = 41/139 (29%), Positives = 56/139 (40%), Gaps = 24/139 (17%)

Query: 538 RPSTEEPVRRPQRPRSPPLPAVIRNAPSRPPSLPTPRPASQPRKAPVISSTPKLPALAAR 597
           R S   P  R +R  SP  P   R  P+ PP   TP P  + R     S +P+      R
Sbjct: 547 RRSPSPPPTRRRRSPSPAPPPRRRRTPTPPPRRRTPSPPPRRR-----SPSPR------R 595

Query: 598 EEASTSRLLQPPEAPRKPANTLVKTASRPAPLVQQLSPSLLPNSKSPREVPSPKVIKTPV 657
                 R   P   P++      +TAS P P  ++ SPS  P  +     P PK   +PV
Sbjct: 596 YSPPIQRRYSPSPPPKR------RTASPPPPPKRRASPSPPPKRRVSHS-PPPKQRSSPV 648

Query: 658 VKKTESPIKLSPATPSRKR 676
            K+       SP+  S+ R
Sbjct: 649 TKRR------SPSLSSKHR 661



 Score = 42.0 bits (97), Expect = 0.003
 Identities = 50/184 (27%), Positives = 77/184 (41%), Gaps = 28/184 (15%)

Query: 538 RPSTEEPVRRPQRPRSPPLPAVIRNAPSRPPSLPTPRPASQPRKAPVISSTP---KLPAL 594
           R S     R PQ   SPP   V R A S P    +P P+++P +   +S TP   K+   
Sbjct: 681 RHSPSPRPRAPQTSSSPP--PVRRGASSSPQRRQSPSPSTRPIRR--VSRTPEPKKIKKA 736

Query: 595 AAREEASTSRLLQPPEAPRKPANTLVKTASRPAPLVQQLSPSLLPNSKSPREVPSPKVIK 654
           A+    S  R+         P     K  + P+P+           S+SP    SP V  
Sbjct: 737 ASPSPQSVRRVSSSRSVSGSPEPAAKKPPAPPSPV----------QSQSPSTNWSPAV-- 784

Query: 655 TPVVKKTESPIKLSPATPSRKRSVAVSDEEEVEEEAERRKERCKRGRFVVKEEKKDSNEL 714
              VKK +SP   SP+ P        SD+E   ++ +++K++  +     K+ KK   E 
Sbjct: 785 --PVKKAKSPTP-SPSPPRN------SDQEGGGKKKKKKKDKKHKKDKKHKKHKKHKKEK 835

Query: 715 SDSA 718
           + +A
Sbjct: 836 AVAA 839



 Score = 37.7 bits (86), Expect = 0.053
 Identities = 54/264 (20%), Positives = 98/264 (37%), Gaps = 51/264 (19%)

Query: 479 QKQKVPLGTFRKDMKTQEEKQKQLTEKIRQQQEKLEALQKTTPIRSQADLKKLPLEVTTR 538
           Q ++  L + +K  + ++++ K+  E  R+++E+  + ++          +  P+    +
Sbjct: 135 QIEQEKLASMKKQDEDKDKRDKEEKESSREKRERSRSPRRRKSRSPSPRRRSSPVRRERK 194

Query: 539 PSTEEPVRRPQRPRSP-PLPAVIRNAPSRPPSLPTPRPASQPRKAPVISSTPKLPALAAR 597
            S     R   + RSP P P        + P LP P              + K+   + +
Sbjct: 195 RSHSRSPRHRTKSRSPSPAP----EKKEKTPELPEP--------------SVKVKEPSVQ 236

Query: 598 EEASTSRLLQPPEAPRKPANTLVKTASRPAPLVQQLSPSLLPNSKSPREVP-----SPKV 652
           E  STS +L+ P               +P P+ +   PS   NSK  +E       S   
Sbjct: 237 EATSTSDILKVP---------------KPEPIPEPKEPSPEKNSKKEKEKEKTRPRSRSR 281

Query: 653 IKTPVVKKTESPIKLSPATPSRKRSVAVSDEEEV---EEEAERRK---------ERCKRG 700
            K+    ++ SP    P    R RS + S           + RR+          R +R 
Sbjct: 282 SKSRSRTRSRSPSHTRPRRRHRSRSRSYSPRRRPSPRRRPSPRRRTPPRRMPPPPRHRRS 341

Query: 701 RFVVKEEKKDSNELSDSAGEEDSA 724
           R  V+  ++ S  LS S+    S+
Sbjct: 342 RSPVRRRRRSSASLSGSSSSSSSS 365


>gi|21040326 SON DNA-binding protein isoform F [Homo sapiens]
          Length = 2426

 Score = 50.1 bits (118), Expect = 1e-05
 Identities = 41/139 (29%), Positives = 55/139 (39%), Gaps = 10/139 (7%)

Query: 554  PPLPAVIRNAPSRPPSLPTPRPASQPRKAPVI--SSTPKLPALAAREEASTSRLLQPPEA 611
            PPLP      P  PP++P P P  +P   P +     P+ PAL   + A T+    P E 
Sbjct: 1147 PPLP------PEEPPTMP-PLPPEEPPMTPPLPPEEPPEGPALPTEQSALTAENTWPTEV 1199

Query: 612  PRKPANTLVKTASRPAPLVQQLSPSLLPNSKS-PREVPSPKVIKTPVVKKTESPIKLSPA 670
            P  P+   V     P    +   PS +P   S     PS  V +  V      P   S  
Sbjct: 1200 PSSPSEESVSQPEPPVSQSEISEPSAVPTDYSVSASDPSVLVSEAAVTVPEPPPEPESSI 1259

Query: 671  TPSRKRSVAVSDEEEVEEE 689
            T +   S  V++E EV  E
Sbjct: 1260 TLTPVESAVVAEEHEVVPE 1278



 Score = 47.0 bits (110), Expect = 9e-05
 Identities = 54/223 (24%), Positives = 93/223 (41%), Gaps = 15/223 (6%)

Query: 464 SMNPDPEQDRCEASEQKQKVPLGTFRKDMKTQEEKQKQLTE----KIRQQQEKLEALQKT 519
           S+  DP  +      +K K      +K  K +E+K K+  E    K +   +    L+  
Sbjct: 94  SVQTDPTDEIPTKKSKKHKKHKNKKKKKKKEKEKKYKRQPEESESKTKSHDDGNIDLESD 153

Query: 520 TPIRSQADLKKLPLEVTTRPSTEEPVRRPQRPRSPPLPAVIRNAPSRPPSLPTPRPASQP 579
           + ++  ++   + LE+ TR     P    + P     P V+    S P  L T +PA++ 
Sbjct: 154 SFLKFDSEPSAVALELPTRAFG--PSETNESPAVVLEPPVVSMEVSEPHILETLKPATKT 211

Query: 580 RKAPVIS----STPKLPALAAREEASTSRLLQPPEAPRKPANTLVKTASRPAPL--VQQL 633
            +  V+S    S     ++A   E S +++L    A   P  TLV  +S P     V+  
Sbjct: 212 AELSVVSTSVISEQSEQSVAVMPEPSMTKILDSFAAAPVPTTTLVLKSSEPVVTMSVEYQ 271

Query: 634 SPSLLPNSKSPREVPSPKVIKTPVVKKTESP---IKLSPATPS 673
             S+L + +S    PS  ++  P V K   P   + +S  TP+
Sbjct: 272 MKSVLKSVESTSPEPSKIMLVEPPVAKVLEPSETLVVSSETPT 314


>gi|21040314 SON DNA-binding protein isoform B [Homo sapiens]
          Length = 2303

 Score = 50.1 bits (118), Expect = 1e-05
 Identities = 41/139 (29%), Positives = 55/139 (39%), Gaps = 10/139 (7%)

Query: 554  PPLPAVIRNAPSRPPSLPTPRPASQPRKAPVI--SSTPKLPALAAREEASTSRLLQPPEA 611
            PPLP      P  PP++P P P  +P   P +     P+ PAL   + A T+    P E 
Sbjct: 1147 PPLP------PEEPPTMP-PLPPEEPPMTPPLPPEEPPEGPALPTEQSALTAENTWPTEV 1199

Query: 612  PRKPANTLVKTASRPAPLVQQLSPSLLPNSKS-PREVPSPKVIKTPVVKKTESPIKLSPA 670
            P  P+   V     P    +   PS +P   S     PS  V +  V      P   S  
Sbjct: 1200 PSSPSEESVSQPEPPVSQSEISEPSAVPTDYSVSASDPSVLVSEAAVTVPEPPPEPESSI 1259

Query: 671  TPSRKRSVAVSDEEEVEEE 689
            T +   S  V++E EV  E
Sbjct: 1260 TLTPVESAVVAEEHEVVPE 1278



 Score = 47.0 bits (110), Expect = 9e-05
 Identities = 54/223 (24%), Positives = 93/223 (41%), Gaps = 15/223 (6%)

Query: 464 SMNPDPEQDRCEASEQKQKVPLGTFRKDMKTQEEKQKQLTE----KIRQQQEKLEALQKT 519
           S+  DP  +      +K K      +K  K +E+K K+  E    K +   +    L+  
Sbjct: 94  SVQTDPTDEIPTKKSKKHKKHKNKKKKKKKEKEKKYKRQPEESESKTKSHDDGNIDLESD 153

Query: 520 TPIRSQADLKKLPLEVTTRPSTEEPVRRPQRPRSPPLPAVIRNAPSRPPSLPTPRPASQP 579
           + ++  ++   + LE+ TR     P    + P     P V+    S P  L T +PA++ 
Sbjct: 154 SFLKFDSEPSAVALELPTRAFG--PSETNESPAVVLEPPVVSMEVSEPHILETLKPATKT 211

Query: 580 RKAPVIS----STPKLPALAAREEASTSRLLQPPEAPRKPANTLVKTASRPAPL--VQQL 633
            +  V+S    S     ++A   E S +++L    A   P  TLV  +S P     V+  
Sbjct: 212 AELSVVSTSVISEQSEQSVAVMPEPSMTKILDSFAAAPVPTTTLVLKSSEPVVTMSVEYQ 271

Query: 634 SPSLLPNSKSPREVPSPKVIKTPVVKKTESP---IKLSPATPS 673
             S+L + +S    PS  ++  P V K   P   + +S  TP+
Sbjct: 272 MKSVLKSVESTSPEPSKIMLVEPPVAKVLEPSETLVVSSETPT 314


>gi|116284392 mucin 2 precursor [Homo sapiens]
          Length = 5179

 Score = 49.7 bits (117), Expect = 1e-05
 Identities = 39/164 (23%), Positives = 55/164 (33%), Gaps = 11/164 (6%)

Query: 519  TTPIRSQADLKKLPLEVTTRP-----STEEPVRRPQRPRSPPLPAVIRNAPSRPPSLPTP 573
            TTPI   A    LP   T  P     +T  P   P  P + P+          P + P+P
Sbjct: 1505 TTPITPPASTTTLPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTPSP 1564

Query: 574  RPASQPRKAPVISSTPKLPALAAREEASTSRLLQPPEAPRKPANTLVKT----ASRPAPL 629
             P +     P  ++TP  P        + +    PP     P  T   T     +   P 
Sbjct: 1565 PPTTTTTPPP--TTTPSPPTTTTPSPPTITTTTPPPTTTPSPPTTTTTTPPPTTTPSPPT 1622

Query: 630  VQQLSPSLLPNSKSPREVPSPKVIKTPVVKKTESPIKLSPATPS 673
               ++P     +  P   PSP    T     T +P   +  TPS
Sbjct: 1623 TTPITPPTSTTTLPPTTTPSPPPTTTTTPPPTTTPSPPTTTTPS 1666



 Score = 48.5 bits (114), Expect = 3e-05
 Identities = 38/153 (24%), Positives = 55/153 (35%), Gaps = 14/153 (9%)

Query: 532  PLEVTTRPSTEEPVRRPQRPRSPPLPAVIRNAP-----SRPPSLPTPRPASQPRKAPVIS 586
            P+  TT P    P   P  P + P P     +P     + PP   TP P +     P  S
Sbjct: 1457 PISTTTTPP---PTTTPSPPTTTPSPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPAS 1513

Query: 587  STPKLPALAAREEASTSRLLQPPEAPRKPANTLVKTASRPAPLVQQLSPSLLPNSKS--- 643
            +T   P        +T+    P   P  P  T +   +    L    +PS  P + +   
Sbjct: 1514 TTTLPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTPSPPPTTTTTPP 1573

Query: 644  PREVPSPKVIKT---PVVKKTESPIKLSPATPS 673
            P   PSP    T   P +  T  P   +P+ P+
Sbjct: 1574 PTTTPSPPTTTTPSPPTITTTTPPPTTTPSPPT 1606



 Score = 47.0 bits (110), Expect = 9e-05
 Identities = 38/144 (26%), Positives = 50/144 (34%), Gaps = 7/144 (4%)

Query: 532  PLEVTTRPSTEEPVRRPQRPRSPPLPAVIRNAPSRPPSLP---TPRPASQPRKAPVISST 588
            P   TT P T  P        SPP+       P+  PS P   TP P +     P  ++T
Sbjct: 1645 PTTTTTPPPTTTPSPPTTTTPSPPITTTTTPPPTTTPSSPITTTPSPPTTTMTTPSPTTT 1704

Query: 589  PKLPALAAREEASTSRLLQPPEAPRKPANTLVKTASRPAPLVQQLSPSLLPNSKSPREVP 648
            P  P       +ST+    PP     P+ T   T S P   +  L P+    S      P
Sbjct: 1705 PSSPITTTTTPSSTTTPSPPPTTMTTPSPT--TTPSPPTTTMTTLPPT--TTSSPLTTTP 1760

Query: 649  SPKVIKTPVVKKTESPIKLSPATP 672
             P  I  P      +    +P  P
Sbjct: 1761 LPPSITPPTFSPFSTTTPTTPCVP 1784



 Score = 45.4 bits (106), Expect = 3e-04
 Identities = 45/163 (27%), Positives = 55/163 (33%), Gaps = 19/163 (11%)

Query: 519  TTPIRSQADLKKLPLEVTTRPSTEEPVRRPQRPRSPPLPAVIRNAPSRPPSLP-----TP 573
            TTP          P   TT P T  P        SPP        P+  PS P     TP
Sbjct: 1397 TTPSPPTTTPSPPPTSTTTLPPTTTP--------SPPTTTTTTPPPTTTPSPPITTTTTP 1448

Query: 574  RPASQPRKAPVISSTPKLPALAAREEAST--SRLLQPPEAPRKPANTLVKTASRPAPLVQ 631
             P + P  +P IS+T   P        +T  S     P  P     T   T +   P   
Sbjct: 1449 PPTTTP--SPPISTTTTPPPTTTPSPPTTTPSPPTTTPSPPTTTTTTPPPTTTPSPPTTT 1506

Query: 632  QLSPSLLPNSKSPREVPSP--KVIKTPVVKKTESPIKLSPATP 672
             ++P     +  P   PSP      TP    T SP   +P TP
Sbjct: 1507 PITPPASTTTLPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITP 1549



 Score = 45.4 bits (106), Expect = 3e-04
 Identities = 41/165 (24%), Positives = 52/165 (31%), Gaps = 12/165 (7%)

Query: 519  TTPIRSQADLKKLPLEVTTRP-----STEEPVRRPQRPRSP-PLPAVIRNAPSRPPSLPT 572
            TTPI        LP   T  P     +T  P   P  P +  P P  I    + PP   T
Sbjct: 1544 TTPITPPTSTTTLPPTTTPSPPPTTTTTPPPTTTPSPPTTTTPSPPTITT--TTPPPTTT 1601

Query: 573  PRPASQPRKAPVISSTPKLPALAAREEASTSRLLQPPEAPRKPANTLVK----TASRPAP 628
            P P +     P  ++TP  P        +++  L P   P  P  T       T   P  
Sbjct: 1602 PSPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTPSPPPTTTTTPPPTTTPSPPT 1661

Query: 629  LVQQLSPSLLPNSKSPREVPSPKVIKTPVVKKTESPIKLSPATPS 673
                  P     +  P   PS  +  TP    T         TPS
Sbjct: 1662 TTTPSPPITTTTTPPPTTTPSSPITTTPSPPTTTMTTPSPTTTPS 1706



 Score = 41.6 bits (96), Expect = 0.004
 Identities = 38/135 (28%), Positives = 49/135 (36%), Gaps = 11/135 (8%)

Query: 536  TTRPSTEEPVRRPQRPRSPPLPAVI---RNAPSRPPSLPT-PRPASQPRKAPVISSTPKL 591
            TT P T  P      P +PP           PS PP+  T P P + P  +P  ++TP  
Sbjct: 1610 TTPPPTTTPSPPTTTPITPPTSTTTLPPTTTPSPPPTTTTTPPPTTTP--SPPTTTTPSP 1667

Query: 592  PALAAREEASTSRLLQPPEAPRKPANTLVKTASRPAPLVQQLSPSLLPNSKSPREVPS-- 649
            P         T+    P      P  T   T + P+P     SP     + S    PS  
Sbjct: 1668 PITTTTTPPPTTTPSSPITTTPSPPTT---TMTTPSPTTTPSSPITTTTTPSSTTTPSPP 1724

Query: 650  PKVIKTPVVKKTESP 664
            P  + TP    T SP
Sbjct: 1725 PTTMTTPSPTTTPSP 1739



 Score = 40.4 bits (93), Expect = 0.008
 Identities = 39/151 (25%), Positives = 51/151 (33%), Gaps = 13/151 (8%)

Query: 532  PLEVTT---RPSTEEPVRRPQRPRSPPLPAVIRNAPSRPPSLP---TPRPASQPRKAPVI 585
            P   TT    P T      P    SPP        P+  PS P   TP P       P  
Sbjct: 1618 PSPPTTTPITPPTSTTTLPPTTTPSPPPTTTTTPPPTTTPSPPTTTTPSPPITTTTTPPP 1677

Query: 586  SSTPKLPALAAREEASTSRLL-QPPEAPRKPANTLVKTASRPAPLVQQLSPSLLPNSKSP 644
            ++TP  P        +T+     P   P  P    + T + P+       P     + SP
Sbjct: 1678 TTTPSSPITTTPSPPTTTMTTPSPTTTPSSP----ITTTTTPSSTTTPSPPPTTMTTPSP 1733

Query: 645  REVPSP--KVIKTPVVKKTESPIKLSPATPS 673
               PSP    + T     T SP+  +P  PS
Sbjct: 1734 TTTPSPPTTTMTTLPPTTTSSPLTTTPLPPS 1764



 Score = 37.7 bits (86), Expect = 0.053
 Identities = 37/164 (22%), Positives = 61/164 (37%), Gaps = 16/164 (9%)

Query: 519  TTPIRSQADLKKLPLEVTTRPSTEEPVRRPQRPRSPPLPAVIRNAPSRPPSL-----PTP 573
            TTPI +   +   P    T+  T  P+         P P   +   + P +      PTP
Sbjct: 4129 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 4188

Query: 574  RPASQPRKAPVISSTPKLPALAARE---EASTSRLLQPPEAPRKPANTLVKTASRPAPLV 630
             P       P  +ST  +  L       E+ST +  +   +P   + TL+ T     P  
Sbjct: 4189 TPTGTQTGPPTHTSTAPIAELTTSNPPPESSTPQTSRSTSSPLTESTTLLST----LPPA 4244

Query: 631  QQLSPSLLPNSKSPREVPSPKVIKTPVVKKTESPIKLSPATPSR 674
             +++ +  P++ +     S     +P    T SP    P TP+R
Sbjct: 4245 IEMTSTAPPSTPTAPTTTSGGHTLSPPPSTTTSP----PGTPTR 4284



 Score = 34.7 bits (78), Expect = 0.44
 Identities = 38/171 (22%), Positives = 53/171 (30%), Gaps = 25/171 (14%)

Query: 519  TTPIRSQADLKKLPLEVTTRPSTEEPVRRPQRPRSPPLPAVIRNAPSRP-------PSLP 571
            TTPI +   +   P    T+  T  P+         P P   +   + P          P
Sbjct: 4083 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 4142

Query: 572  TPRPASQPRKAPVISSTPKLPALAAREEASTSRLLQPPEAPRKPANTLVKTASRPAPLVQ 631
            TP     P   P+ ++T   P         T    Q P     P  T       P P   
Sbjct: 4143 TPTGTQTPTTTPITTTTTVTP-------TPTPTGTQTPTT--TPITTTTTVTPTPTPTGT 4193

Query: 632  QLSP---------SLLPNSKSPREVPSPKVIKTPVVKKTESPIKLSPATPS 673
            Q  P         + L  S  P E  +P+  ++     TES   LS   P+
Sbjct: 4194 QTGPPTHTSTAPIAELTTSNPPPESSTPQTSRSTSSPLTESTTLLSTLPPA 4244



 Score = 31.6 bits (70), Expect = 3.8
 Identities = 34/160 (21%), Positives = 52/160 (32%), Gaps = 21/160 (13%)

Query: 519  TTPIRSQADLKKLPLEVTTRPSTEEPVRRPQRPRSPPLPAVIRNAPSRP-------PSLP 571
            TTPI +   +   P    T+  T  P+         P P   +   + P          P
Sbjct: 1898 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 1957

Query: 572  TPRPASQPRKAPVISSTPKLPALAAREEASTSRLLQPPEAPRKPANTLVKTASRPAPLVQ 631
            TP     P   P+ ++T   P         T    Q P     P  T       P P   
Sbjct: 1958 TPTGTQTPTTTPITTTTTVTP-------TPTPTGTQTPTT--TPITTTTTVTPTPTPTGT 2008

Query: 632  QLSPSLLPNSKSPREVPSPKVIKTPVVKKTESPIKLSPAT 671
            Q +P+  P + +    P+P    TP   +T +   ++  T
Sbjct: 2009 Q-TPTTTPITTTTTVTPTP----TPTGTQTPTTTPITTTT 2043



 Score = 31.6 bits (70), Expect = 3.8
 Identities = 34/160 (21%), Positives = 52/160 (32%), Gaps = 21/160 (13%)

Query: 519  TTPIRSQADLKKLPLEVTTRPSTEEPVRRPQRPRSPPLPAVIRNAPSRP-------PSLP 571
            TTPI +   +   P    T+  T  P+         P P   +   + P          P
Sbjct: 2013 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 2072

Query: 572  TPRPASQPRKAPVISSTPKLPALAAREEASTSRLLQPPEAPRKPANTLVKTASRPAPLVQ 631
            TP     P   P+ ++T   P         T    Q P     P  T       P P   
Sbjct: 2073 TPTGTQTPTTTPITTTTTVTP-------TPTPTGTQTPTT--TPITTTTTVTPTPTPTGT 2123

Query: 632  QLSPSLLPNSKSPREVPSPKVIKTPVVKKTESPIKLSPAT 671
            Q +P+  P + +    P+P    TP   +T +   ++  T
Sbjct: 2124 Q-TPTTTPITTTTTVTPTP----TPTGTQTPTTTPITTTT 2158



 Score = 31.6 bits (70), Expect = 3.8
 Identities = 34/160 (21%), Positives = 52/160 (32%), Gaps = 21/160 (13%)

Query: 519  TTPIRSQADLKKLPLEVTTRPSTEEPVRRPQRPRSPPLPAVIRNAPSRP-------PSLP 571
            TTPI +   +   P    T+  T  P+         P P   +   + P          P
Sbjct: 2128 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 2187

Query: 572  TPRPASQPRKAPVISSTPKLPALAAREEASTSRLLQPPEAPRKPANTLVKTASRPAPLVQ 631
            TP     P   P+ ++T   P         T    Q P     P  T       P P   
Sbjct: 2188 TPTGTQTPTTTPITTTTTVTP-------TPTPTGTQTPTT--TPITTTTTVTPTPTPTGT 2238

Query: 632  QLSPSLLPNSKSPREVPSPKVIKTPVVKKTESPIKLSPAT 671
            Q +P+  P + +    P+P    TP   +T +   ++  T
Sbjct: 2239 Q-TPTTTPITTTTTVTPTP----TPTGTQTPTTTPITTTT 2273



 Score = 31.6 bits (70), Expect = 3.8
 Identities = 34/160 (21%), Positives = 52/160 (32%), Gaps = 21/160 (13%)

Query: 519  TTPIRSQADLKKLPLEVTTRPSTEEPVRRPQRPRSPPLPAVIRNAPSRP-------PSLP 571
            TTPI +   +   P    T+  T  P+         P P   +   + P          P
Sbjct: 2243 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 2302

Query: 572  TPRPASQPRKAPVISSTPKLPALAAREEASTSRLLQPPEAPRKPANTLVKTASRPAPLVQ 631
            TP     P   P+ ++T   P         T    Q P     P  T       P P   
Sbjct: 2303 TPTGTQTPTTTPITTTTTVTP-------TPTPTGTQTPTT--TPITTTTTVTPTPTPTGT 2353

Query: 632  QLSPSLLPNSKSPREVPSPKVIKTPVVKKTESPIKLSPAT 671
            Q +P+  P + +    P+P    TP   +T +   ++  T
Sbjct: 2354 Q-TPTTTPITTTTTVTPTP----TPTGTQTPTTTPITTTT 2388



 Score = 31.6 bits (70), Expect = 3.8
 Identities = 34/160 (21%), Positives = 52/160 (32%), Gaps = 21/160 (13%)

Query: 519  TTPIRSQADLKKLPLEVTTRPSTEEPVRRPQRPRSPPLPAVIRNAPSRP-------PSLP 571
            TTPI +   +   P    T+  T  P+         P P   +   + P          P
Sbjct: 2358 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 2417

Query: 572  TPRPASQPRKAPVISSTPKLPALAAREEASTSRLLQPPEAPRKPANTLVKTASRPAPLVQ 631
            TP     P   P+ ++T   P         T    Q P     P  T       P P   
Sbjct: 2418 TPTGTQTPTTTPITTTTTVTP-------TPTPTGTQTPTT--TPITTTTTVTPTPTPTGT 2468

Query: 632  QLSPSLLPNSKSPREVPSPKVIKTPVVKKTESPIKLSPAT 671
            Q +P+  P + +    P+P    TP   +T +   ++  T
Sbjct: 2469 Q-TPTTTPITTTTTVTPTP----TPTGTQTPTTTPITTTT 2503



 Score = 31.6 bits (70), Expect = 3.8
 Identities = 34/160 (21%), Positives = 52/160 (32%), Gaps = 21/160 (13%)

Query: 519  TTPIRSQADLKKLPLEVTTRPSTEEPVRRPQRPRSPPLPAVIRNAPSRP-------PSLP 571
            TTPI +   +   P    T+  T  P+         P P   +   + P          P
Sbjct: 2473 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 2532

Query: 572  TPRPASQPRKAPVISSTPKLPALAAREEASTSRLLQPPEAPRKPANTLVKTASRPAPLVQ 631
            TP     P   P+ ++T   P         T    Q P     P  T       P P   
Sbjct: 2533 TPTGTQTPTTTPITTTTTVTP-------TPTPTGTQTPTT--TPITTTTTVTPTPTPTGT 2583

Query: 632  QLSPSLLPNSKSPREVPSPKVIKTPVVKKTESPIKLSPAT 671
            Q +P+  P + +    P+P    TP   +T +   ++  T
Sbjct: 2584 Q-TPTTTPITTTTTVTPTP----TPTGTQTPTTTPITTTT 2618



 Score = 31.6 bits (70), Expect = 3.8
 Identities = 34/160 (21%), Positives = 52/160 (32%), Gaps = 21/160 (13%)

Query: 519  TTPIRSQADLKKLPLEVTTRPSTEEPVRRPQRPRSPPLPAVIRNAPSRP-------PSLP 571
            TTPI +   +   P    T+  T  P+         P P   +   + P          P
Sbjct: 2588 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 2647

Query: 572  TPRPASQPRKAPVISSTPKLPALAAREEASTSRLLQPPEAPRKPANTLVKTASRPAPLVQ 631
            TP     P   P+ ++T   P         T    Q P     P  T       P P   
Sbjct: 2648 TPTGTQTPTTTPITTTTTVTP-------TPTPTGTQTPTT--TPITTTTTVTPTPTPTGT 2698

Query: 632  QLSPSLLPNSKSPREVPSPKVIKTPVVKKTESPIKLSPAT 671
            Q +P+  P + +    P+P    TP   +T +   ++  T
Sbjct: 2699 Q-TPTTTPITTTTTVTPTP----TPTGTQTPTTTPITTTT 2733



 Score = 31.6 bits (70), Expect = 3.8
 Identities = 34/160 (21%), Positives = 52/160 (32%), Gaps = 21/160 (13%)

Query: 519  TTPIRSQADLKKLPLEVTTRPSTEEPVRRPQRPRSPPLPAVIRNAPSRP-------PSLP 571
            TTPI +   +   P    T+  T  P+         P P   +   + P          P
Sbjct: 2703 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 2762

Query: 572  TPRPASQPRKAPVISSTPKLPALAAREEASTSRLLQPPEAPRKPANTLVKTASRPAPLVQ 631
            TP     P   P+ ++T   P         T    Q P     P  T       P P   
Sbjct: 2763 TPTGTQTPTTTPITTTTTVTP-------TPTPTGTQTPTT--TPITTTTTVTPTPTPTGT 2813

Query: 632  QLSPSLLPNSKSPREVPSPKVIKTPVVKKTESPIKLSPAT 671
            Q +P+  P + +    P+P    TP   +T +   ++  T
Sbjct: 2814 Q-TPTTTPITTTTTVTPTP----TPTGTQTPTTTPITTTT 2848



 Score = 31.6 bits (70), Expect = 3.8
 Identities = 34/160 (21%), Positives = 52/160 (32%), Gaps = 21/160 (13%)

Query: 519  TTPIRSQADLKKLPLEVTTRPSTEEPVRRPQRPRSPPLPAVIRNAPSRP-------PSLP 571
            TTPI +   +   P    T+  T  P+         P P   +   + P          P
Sbjct: 2818 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 2877

Query: 572  TPRPASQPRKAPVISSTPKLPALAAREEASTSRLLQPPEAPRKPANTLVKTASRPAPLVQ 631
            TP     P   P+ ++T   P         T    Q P     P  T       P P   
Sbjct: 2878 TPTGTQTPTTTPITTTTTVTP-------TPTPTGTQTPTT--TPITTTTTVTPTPTPTGT 2928

Query: 632  QLSPSLLPNSKSPREVPSPKVIKTPVVKKTESPIKLSPAT 671
            Q +P+  P + +    P+P    TP   +T +   ++  T
Sbjct: 2929 Q-TPTTTPITTTTTVTPTP----TPTGTQTPTTTPITTTT 2963



 Score = 31.6 bits (70), Expect = 3.8
 Identities = 34/160 (21%), Positives = 52/160 (32%), Gaps = 21/160 (13%)

Query: 519  TTPIRSQADLKKLPLEVTTRPSTEEPVRRPQRPRSPPLPAVIRNAPSRP-------PSLP 571
            TTPI +   +   P    T+  T  P+         P P   +   + P          P
Sbjct: 2933 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 2992

Query: 572  TPRPASQPRKAPVISSTPKLPALAAREEASTSRLLQPPEAPRKPANTLVKTASRPAPLVQ 631
            TP     P   P+ ++T   P         T    Q P     P  T       P P   
Sbjct: 2993 TPTGTQTPTTTPITTTTTVTP-------TPTPTGTQTPTT--TPITTTTTVTPTPTPTGT 3043

Query: 632  QLSPSLLPNSKSPREVPSPKVIKTPVVKKTESPIKLSPAT 671
            Q +P+  P + +    P+P    TP   +T +   ++  T
Sbjct: 3044 Q-TPTTTPITTTTTVTPTP----TPTGTQTPTTTPITTTT 3078



 Score = 31.6 bits (70), Expect = 3.8
 Identities = 34/160 (21%), Positives = 52/160 (32%), Gaps = 21/160 (13%)

Query: 519  TTPIRSQADLKKLPLEVTTRPSTEEPVRRPQRPRSPPLPAVIRNAPSRP-------PSLP 571
            TTPI +   +   P    T+  T  P+         P P   +   + P          P
Sbjct: 3048 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 3107

Query: 572  TPRPASQPRKAPVISSTPKLPALAAREEASTSRLLQPPEAPRKPANTLVKTASRPAPLVQ 631
            TP     P   P+ ++T   P         T    Q P     P  T       P P   
Sbjct: 3108 TPTGTQTPTTTPITTTTTVTP-------TPTPTGTQTPTT--TPITTTTTVTPTPTPTGT 3158

Query: 632  QLSPSLLPNSKSPREVPSPKVIKTPVVKKTESPIKLSPAT 671
            Q +P+  P + +    P+P    TP   +T +   ++  T
Sbjct: 3159 Q-TPTTTPITTTTTVTPTP----TPTGTQTPTTTPITTTT 3193



 Score = 31.6 bits (70), Expect = 3.8
 Identities = 34/160 (21%), Positives = 52/160 (32%), Gaps = 21/160 (13%)

Query: 519  TTPIRSQADLKKLPLEVTTRPSTEEPVRRPQRPRSPPLPAVIRNAPSRP-------PSLP 571
            TTPI +   +   P    T+  T  P+         P P   +   + P          P
Sbjct: 3163 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 3222

Query: 572  TPRPASQPRKAPVISSTPKLPALAAREEASTSRLLQPPEAPRKPANTLVKTASRPAPLVQ 631
            TP     P   P+ ++T   P         T    Q P     P  T       P P   
Sbjct: 3223 TPTGTQTPTTTPITTTTTVTP-------TPTPTGTQTPTT--TPITTTTTVTPTPTPTGT 3273

Query: 632  QLSPSLLPNSKSPREVPSPKVIKTPVVKKTESPIKLSPAT 671
            Q +P+  P + +    P+P    TP   +T +   ++  T
Sbjct: 3274 Q-TPTTTPITTTTTVTPTP----TPTGTQTPTTTPITTTT 3308



 Score = 31.6 bits (70), Expect = 3.8
 Identities = 34/160 (21%), Positives = 52/160 (32%), Gaps = 21/160 (13%)

Query: 519  TTPIRSQADLKKLPLEVTTRPSTEEPVRRPQRPRSPPLPAVIRNAPSRP-------PSLP 571
            TTPI +   +   P    T+  T  P+         P P   +   + P          P
Sbjct: 3278 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 3337

Query: 572  TPRPASQPRKAPVISSTPKLPALAAREEASTSRLLQPPEAPRKPANTLVKTASRPAPLVQ 631
            TP     P   P+ ++T   P         T    Q P     P  T       P P   
Sbjct: 3338 TPTGTQTPTTTPITTTTTVTP-------TPTPTGTQTPTT--TPITTTTTVTPTPTPTGT 3388

Query: 632  QLSPSLLPNSKSPREVPSPKVIKTPVVKKTESPIKLSPAT 671
            Q +P+  P + +    P+P    TP   +T +   ++  T
Sbjct: 3389 Q-TPTTTPITTTTTVTPTP----TPTGTQTPTTTPITTTT 3423



 Score = 31.6 bits (70), Expect = 3.8
 Identities = 34/160 (21%), Positives = 52/160 (32%), Gaps = 21/160 (13%)

Query: 519  TTPIRSQADLKKLPLEVTTRPSTEEPVRRPQRPRSPPLPAVIRNAPSRP-------PSLP 571
            TTPI +   +   P    T+  T  P+         P P   +   + P          P
Sbjct: 3393 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 3452

Query: 572  TPRPASQPRKAPVISSTPKLPALAAREEASTSRLLQPPEAPRKPANTLVKTASRPAPLVQ 631
            TP     P   P+ ++T   P         T    Q P     P  T       P P   
Sbjct: 3453 TPTGTQTPTTTPITTTTTVTP-------TPTPTGTQTPTT--TPITTTTTVTPTPTPTGT 3503

Query: 632  QLSPSLLPNSKSPREVPSPKVIKTPVVKKTESPIKLSPAT 671
            Q +P+  P + +    P+P    TP   +T +   ++  T
Sbjct: 3504 Q-TPTTTPITTTTTVTPTP----TPTGTQTPTTTPITTTT 3538



 Score = 31.6 bits (70), Expect = 3.8
 Identities = 34/160 (21%), Positives = 52/160 (32%), Gaps = 21/160 (13%)

Query: 519  TTPIRSQADLKKLPLEVTTRPSTEEPVRRPQRPRSPPLPAVIRNAPSRP-------PSLP 571
            TTPI +   +   P    T+  T  P+         P P   +   + P          P
Sbjct: 3508 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 3567

Query: 572  TPRPASQPRKAPVISSTPKLPALAAREEASTSRLLQPPEAPRKPANTLVKTASRPAPLVQ 631
            TP     P   P+ ++T   P         T    Q P     P  T       P P   
Sbjct: 3568 TPTGTQTPTTTPITTTTTVTP-------TPTPTGTQTPTT--TPITTTTTVTPTPTPTGT 3618

Query: 632  QLSPSLLPNSKSPREVPSPKVIKTPVVKKTESPIKLSPAT 671
            Q +P+  P + +    P+P    TP   +T +   ++  T
Sbjct: 3619 Q-TPTTTPITTTTTVTPTP----TPTGTQTPTTTPITTTT 3653



 Score = 31.6 bits (70), Expect = 3.8
 Identities = 34/160 (21%), Positives = 52/160 (32%), Gaps = 21/160 (13%)

Query: 519  TTPIRSQADLKKLPLEVTTRPSTEEPVRRPQRPRSPPLPAVIRNAPSRP-------PSLP 571
            TTPI +   +   P    T+  T  P+         P P   +   + P          P
Sbjct: 3623 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 3682

Query: 572  TPRPASQPRKAPVISSTPKLPALAAREEASTSRLLQPPEAPRKPANTLVKTASRPAPLVQ 631
            TP     P   P+ ++T   P         T    Q P     P  T       P P   
Sbjct: 3683 TPTGTQTPTTTPITTTTTVTP-------TPTPTGTQTPTT--TPITTTTTVTPTPTPTGT 3733

Query: 632  QLSPSLLPNSKSPREVPSPKVIKTPVVKKTESPIKLSPAT 671
            Q +P+  P + +    P+P    TP   +T +   ++  T
Sbjct: 3734 Q-TPTTTPITTTTTVTPTP----TPTGTQTPTTTPITTTT 3768



 Score = 31.6 bits (70), Expect = 3.8
 Identities = 34/160 (21%), Positives = 52/160 (32%), Gaps = 21/160 (13%)

Query: 519  TTPIRSQADLKKLPLEVTTRPSTEEPVRRPQRPRSPPLPAVIRNAPSRP-------PSLP 571
            TTPI +   +   P    T+  T  P+         P P   +   + P          P
Sbjct: 3738 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 3797

Query: 572  TPRPASQPRKAPVISSTPKLPALAAREEASTSRLLQPPEAPRKPANTLVKTASRPAPLVQ 631
            TP     P   P+ ++T   P         T    Q P     P  T       P P   
Sbjct: 3798 TPTGTQTPTTTPITTTTTVTP-------TPTPTGTQTPTT--TPITTTTTVTPTPTPTGT 3848

Query: 632  QLSPSLLPNSKSPREVPSPKVIKTPVVKKTESPIKLSPAT 671
            Q +P+  P + +    P+P    TP   +T +   ++  T
Sbjct: 3849 Q-TPTTTPITTTTTVTPTP----TPTGTQTPTTTPITTTT 3883



 Score = 31.6 bits (70), Expect = 3.8
 Identities = 34/160 (21%), Positives = 52/160 (32%), Gaps = 21/160 (13%)

Query: 519  TTPIRSQADLKKLPLEVTTRPSTEEPVRRPQRPRSPPLPAVIRNAPSRP-------PSLP 571
            TTPI +   +   P    T+  T  P+         P P   +   + P          P
Sbjct: 3853 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 3912

Query: 572  TPRPASQPRKAPVISSTPKLPALAAREEASTSRLLQPPEAPRKPANTLVKTASRPAPLVQ 631
            TP     P   P+ ++T   P         T    Q P     P  T       P P   
Sbjct: 3913 TPTGTQTPTTTPITTTTTVTP-------TPTPTGTQTPTT--TPITTTTTVTPTPTPTGT 3963

Query: 632  QLSPSLLPNSKSPREVPSPKVIKTPVVKKTESPIKLSPAT 671
            Q +P+  P + +    P+P    TP   +T +   ++  T
Sbjct: 3964 Q-TPTTTPITTTTTVTPTP----TPTGTQTPTTTPITTTT 3998



 Score = 31.6 bits (70), Expect = 3.8
 Identities = 34/160 (21%), Positives = 52/160 (32%), Gaps = 21/160 (13%)

Query: 519  TTPIRSQADLKKLPLEVTTRPSTEEPVRRPQRPRSPPLPAVIRNAPSRP-------PSLP 571
            TTPI +   +   P    T+  T  P+         P P   +   + P          P
Sbjct: 3968 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 4027

Query: 572  TPRPASQPRKAPVISSTPKLPALAAREEASTSRLLQPPEAPRKPANTLVKTASRPAPLVQ 631
            TP     P   P+ ++T   P         T    Q P     P  T       P P   
Sbjct: 4028 TPTGTQTPTTTPITTTTTVTP-------TPTPTGTQTPTT--TPITTTTTVTPTPTPTGT 4078

Query: 632  QLSPSLLPNSKSPREVPSPKVIKTPVVKKTESPIKLSPAT 671
            Q +P+  P + +    P+P    TP   +T +   ++  T
Sbjct: 4079 Q-TPTTTPITTTTTVTPTP----TPTGTQTPTTTPITTTT 4113


>gi|38788260 bromodomain PHD finger transcription factor isoform 2
            [Homo sapiens]
          Length = 2903

 Score = 49.3 bits (116), Expect = 2e-05
 Identities = 62/281 (22%), Positives = 123/281 (43%), Gaps = 50/281 (17%)

Query: 494  TQEEKQKQLTEKIRQQQEKLEALQKTTPIRSQADLKKLPLEVTTRPSTEEPVRRPQ---R 550
            T E++Q +L+ +++  Q+K      T P    + +   P E   +P T +P  +PQ   +
Sbjct: 2361 TGEQRQSKLSPQMQVHQDK------TLPPAQSSSVG--PAEA--QPQTAQPSAQPQPQTQ 2410

Query: 551  PRSPPLPAVIRNAPSRPPSLPTPRPASQ--PRKAPVISSTPKLPALAAREEASTSRLLQP 608
            P+SP  P V        P + T    S   P +A    +    P +AA+ +  ++   Q 
Sbjct: 2411 PQSPAQPEV-----QTQPEVQTQTTVSSHVPSEAQPTHAQSSKPQVAAQSQPQSNVQGQS 2465

Query: 609  PEAPRKPANTLVK-----------------TASRPAPLVQQLSPSLLPNSKSPREVPSPK 651
            P   + P+ T ++                 T S+P P +Q  +   +P+   P+  P   
Sbjct: 2466 PVRVQSPSQTRIRPSTPSQLSPGQQSQVQTTTSQPIP-IQPHTSLQIPSQGQPQSQPQVV 2524

Query: 652  VIKTPVVKKTESPIKLSPATPSRKRSVAVSDE------EEVEEEAERRKERCKRGRFV-V 704
            +    V++  +    ++PA     + + V ++      +++++E ++  ++ KR   V  
Sbjct: 2525 MKHNAVIEHLKQKKSMTPAEREENQRMIVCNQVMKYILDKIDKEEKQAAKKRKREESVEQ 2584

Query: 705  KEEKKDSNELSD---SAGEEDSADL--KRAQKDKGLHVEVR 740
            K  K+++ +LS       E+  A++  KRA  DK L +EV+
Sbjct: 2585 KRSKQNATKLSALLFKHKEQLRAEILKKRALLDKDLQIEVQ 2625



 Score = 39.7 bits (91), Expect = 0.014
 Identities = 40/160 (25%), Positives = 65/160 (40%), Gaps = 17/160 (10%)

Query: 470  EQDRCEASEQKQKVPLGTFRKDMKTQEEKQKQLTEKIRQQQEKLEALQKTTPIRSQADLK 529
            EQ R + +  K    L   ++ ++ +  K++ L +K   Q E  E L++   I+ + DL 
Sbjct: 2583 EQKRSKQNATKLSALLFKHKEQLRAEILKKRALLDK-DLQIEVQEELKRDLKIKKEKDLM 2641

Query: 530  KLPLEVTTRPSTEEPVRRPQRPRSPPLPAVIRNAPSRPPSLPTPRPASQPRKAPVISSTP 589
            +L        +    V  P  P +P  PA     P  PP  P P PA Q      + STP
Sbjct: 2642 QL--------AQATAVAAPCPPVTPAPPA-----PPAPPPSPPPPPAVQHTG---LLSTP 2685

Query: 590  KLPALAAREEASTSRLLQPPEAPRKPANTLVKTASRPAPL 629
             LPA + + +    +        +K  +T  K   +   L
Sbjct: 2686 TLPAASQKRKREEEKDSSSKSKKKKMISTTSKETKKDTKL 2725



 Score = 36.2 bits (82), Expect = 0.15
 Identities = 25/85 (29%), Positives = 36/85 (42%), Gaps = 12/85 (14%)

Query: 546 RRPQRPRSPPLPAVIRNAPSRPPSLPTP------------RPASQPRKAPVISSTPKLPA 593
           RR + P+ P  PA  R AP+ PP  P P            R +S+ R A   +       
Sbjct: 4   RRGRPPKQPAAPAAERCAPAPPPPPPPPTSGPIGGLRSRHRGSSRGRWAAAQAEVAPKTR 63

Query: 594 LAAREEASTSRLLQPPEAPRKPANT 618
           L++    S+SR   PP  P  P+ +
Sbjct: 64  LSSPRGGSSSRRKPPPPPPAPPSTS 88


>gi|32140760 collagen, type XXVII, alpha 1 [Homo sapiens]
          Length = 1860

 Score = 48.9 bits (115), Expect = 2e-05
 Identities = 55/222 (24%), Positives = 82/222 (36%), Gaps = 27/222 (12%)

Query: 473 RCEASEQKQKVPLGTFRKDMKTQEEKQKQLTEKIRQQQEKLEALQKTTPIRSQADLKKLP 532
           R  A++  QK+      K + T+          I+         QKT P  S      LP
Sbjct: 349 RPAAAQPSQKITATKIPKSLPTKPSAPSTSIVPIKSPHPT----QKTAP--SSFTKSALP 402

Query: 533 LEVTTRPSTEEPVRRPQRPRSPPLPAVIRNAPSRPPSLPTPRPASQPRKAPVISSTPK-L 591
            +    P++     R  RP   P+         R P +P P P S     P  SS+ K +
Sbjct: 403 TQKQVPPTSRPVPARVSRPAEKPI--------QRNPGMPRPPPPSTRPLPPTTSSSKKPI 454

Query: 592 PALAAREEASTSRLLQPPEAPRKPANTLVKTASRPAPLVQQLSPSLLPNSKSPREVPSPK 651
           P LA  E   TS   +P  A         +T++   P    LS S  P   S R    P 
Sbjct: 455 PTLARTEAKITSHASKPASA---------RTSTHKPPPFTALSSSPAPTPGSTRSTRPPA 505

Query: 652 VIKTPVVKKTESPIKLSPATPSRKRSVAVSDEEEVEEEAERR 693
            +  P    T +P + +PA P+   S     ++ +  EA ++
Sbjct: 506 TM-VPPTSGTSTP-RTAPAVPT-PGSAPTGSKKPIGSEASKK 544



 Score = 42.7 bits (99), Expect = 0.002
 Identities = 37/133 (27%), Positives = 56/133 (42%), Gaps = 7/133 (5%)

Query: 536 TTRPSTEEPVRRPQRPRSP-PLPAVIRNAPSRPPS--LPTPRPASQPRKAPVISSTPKLP 592
           + R ST +P        SP P P   R+  +RPP+  +P     S PR AP + +    P
Sbjct: 473 SARTSTHKPPPFTALSSSPAPTPGSTRS--TRPPATMVPPTSGTSTPRTAPAVPTPGSAP 530

Query: 593 ALAAREEAS-TSRLLQPPEAPRKPANTLVKTASRPAPLVQQLSPSLLPNSKSPREVPSPK 651
             + +   S  S+   P  +PRKP       A+R  PL   L+    P    P +  +P 
Sbjct: 531 TGSKKPIGSEASKKAGPKSSPRKPVPLRPGKAARDVPL-SDLTTRPSPRQPQPSQQTTPA 589

Query: 652 VIKTPVVKKTESP 664
           ++  P    + SP
Sbjct: 590 LVLAPAQFLSSSP 602


>gi|33286442 BCL6 co-repressor-like 1 [Homo sapiens]
          Length = 1711

 Score = 48.9 bits (115), Expect = 2e-05
 Identities = 45/137 (32%), Positives = 57/137 (41%), Gaps = 30/137 (21%)

Query: 553 SPPLPAVIRNAPSRPPSLPT----------------PRPASQPRKAPVISSTPKLPALAA 596
           SPPL  V   AP+ PPS+PT                P PAS P   PV  S P    L+ 
Sbjct: 249 SPPLAPVPALAPA-PPSVPTLISDSNPLSVSASVLVPVPASAPPSGPVPLSAPAPAPLSV 307

Query: 597 REEASTSRLLQPPEAPRKPANTLVKTASRPAPLVQQLSPSLLPNSKSPREVPSPKVIKTP 656
              A    L+Q P  P  P  TLV  A  P P++  +  S  P + +P  VP P      
Sbjct: 308 PVSAPPLALIQAPVPPSAP--TLV-LAPVPTPVLAPMPASTPPAAPAPPSVPMP------ 358

Query: 657 VVKKTESPIKLSPATPS 673
               T +P    P+TP+
Sbjct: 359 ----TPTPSSGPPSTPT 371



 Score = 40.8 bits (94), Expect = 0.006
 Identities = 43/164 (26%), Positives = 66/164 (40%), Gaps = 22/164 (13%)

Query: 531 LPLEVTTRPSTEEPVRRPQRPRSPPLPAVIRNAPSRPPSLPTP--------------RPA 576
           LPL  T       P+  P  P S  +P  + +A   P S+P P               PA
Sbjct: 189 LPLVTTNFSPLPAPIC-PPAPGSASVPHSVPDAFQVPLSVPAPVPHSGLVPVQVATSVPA 247

Query: 577 SQPRKAPVISSTPKLPALAAREEAS-----TSRLLQPPEAPRKPANTLVKTASRPAPLVQ 631
             P  APV +  P  P++      S     ++ +L P  A   P+  +  +A  PAPL  
Sbjct: 248 PSPPLAPVPALAPAPPSVPTLISDSNPLSVSASVLVPVPASAPPSGPVPLSAPAPAPLSV 307

Query: 632 QLSPSLLPNSKSPREVPSPKVIKTPVVKKTESPIKLS--PATPS 673
            +S   L   ++P    +P ++  PV     +P+  S  PA P+
Sbjct: 308 PVSAPPLALIQAPVPPSAPTLVLAPVPTPVLAPMPASTPPAAPA 351



 Score = 39.3 bits (90), Expect = 0.018
 Identities = 45/167 (26%), Positives = 62/167 (37%), Gaps = 24/167 (14%)

Query: 531 LPLEVTTRPSTEEPVRRPQ---RPRSPPLPAVIRNA--------------PSRPPSLPTP 573
           +P++V T      P   P     P  P +P +I ++               S PPS P P
Sbjct: 237 VPVQVATSVPAPSPPLAPVPALAPAPPSVPTLISDSNPLSVSASVLVPVPASAPPSGPVP 296

Query: 574 RPASQPRKAPVISSTPKLPALAAREEASTSRL-LQPPEAP---RKPANTLVKTASRPAPL 629
             A  P    V  S P L  + A    S   L L P   P     PA+T     + P+  
Sbjct: 297 LSAPAPAPLSVPVSAPPLALIQAPVPPSAPTLVLAPVPTPVLAPMPASTPPAAPAPPSVP 356

Query: 630 VQQLSPSLLPNSKS---PREVPSPKVIKTPVVKKTESPIKLSPATPS 673
           +   +PS  P S     P   P+P    TP    T +P  +  ATP+
Sbjct: 357 MPTPTPSSGPPSTPTLIPAFAPTPVPAPTPAPIFTPAPTPMPAATPA 403



 Score = 35.0 bits (79), Expect = 0.34
 Identities = 30/114 (26%), Positives = 39/114 (34%), Gaps = 20/114 (17%)

Query: 548 PQRPRSPPLPAVIRNAPSRPPSLPTPRPASQPRKAPVISSTPKLPALAAREEASTSRLLQ 607
           P  P  P +P       S PPS PT  PA  P   P  +  P               +  
Sbjct: 347 PAAPAPPSVPMPTPTPSSGPPSTPTLIPAFAPTPVPAPTPAP---------------IFT 391

Query: 608 PPEAPRKPANTLVKTASRPAPLVQQLSPSLLPNSKSP--REVP---SPKVIKTP 656
           P   P   A       S P P    LS    P +++P  ++VP    P  + TP
Sbjct: 392 PAPTPMPAATPAAIPTSAPIPASFSLSRVCFPAAQAPAMQKVPLSFQPGTVLTP 445


>gi|149773456 hypothetical protein LOC643314 [Homo sapiens]
          Length = 1427

 Score = 48.5 bits (114), Expect = 3e-05
 Identities = 48/187 (25%), Positives = 74/187 (39%), Gaps = 19/187 (10%)

Query: 515  ALQKTTPIRSQADLKKLPL-EVTTRPSTEEPVRRPQRPRSPPLPAVIRNAPSRPPS-LPT 572
            A++ +TP    +    +P  E  T P+   P   P+ P SP         P+ P + +PT
Sbjct: 991  AVRVSTPEEPASPAAAVPTPEEPTSPAAAVPT--PEEPTSPAAAVPPPEEPTSPAAAVPT 1048

Query: 573  PRPASQPRKAPVISSTPKLPALAA---REEASTSRLLQPPEAPRKPANTLVKTASRPAPL 629
            P   + P  A      P  PA A     E  S +  +  PE P  PA      A+ P P 
Sbjct: 1049 PEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPA------AAVPTPE 1102

Query: 630  VQQLSPSLLPNSKSPRE----VPSPKVIKTP--VVKKTESPIKLSPATPSRKRSVAVSDE 683
                  + +P  + P      VP+P+   +P   V   E P   +PA P+ + S + +  
Sbjct: 1103 EPTSPAAAVPTPEEPASPAAAVPTPEEPASPAAAVPTPEEPAFPAPAVPTPEESASAAVA 1162

Query: 684  EEVEEEA 690
                EE+
Sbjct: 1163 VPTPEES 1169



 Score = 39.7 bits (91), Expect = 0.014
 Identities = 49/194 (25%), Positives = 67/194 (34%), Gaps = 33/194 (17%)

Query: 467  PDPEQDRCEASEQKQKVPLGTFRKDMKTQEEKQKQLTEKIRQQQEKLEALQKTTPIRSQA 526
            P PE+    A+         +F   + T EE                 A    TP    A
Sbjct: 1164 PTPEESASPAAAVPTPAESASFAAVVATLEEPTSP-------------AASVPTPAAMVA 1210

Query: 527  DLKKLPLEVTTRPSTEEP------VRRPQRPRSPPLPAVIRNAP-SRPPSLPTPRPASQP 579
             L++      + P++EEP      V  P+ P SP         P S   ++ TP   S P
Sbjct: 1211 TLEEFTSPAASVPTSEEPASLAAAVSNPEEPTSPAAAVPTLEEPTSSAAAVLTPEELSSP 1270

Query: 580  RKAPVISSTPKLPALAA---REEASTSRLLQPPEAPRKPANTLVKTASRPAPLVQQLSPS 636
              +      P  PA A     E AS +  +  PE    PA      AS P P V  +  +
Sbjct: 1271 AASVPTPEEPASPAAAVSNLEEPASPAAAVPTPEVAAIPA------ASVPTPEVPAIPAA 1324

Query: 637  LLPNSKSPREVPSP 650
             +P    P E  SP
Sbjct: 1325 AVP----PMEEVSP 1334



 Score = 35.0 bits (79), Expect = 0.34
 Identities = 41/163 (25%), Positives = 58/163 (35%), Gaps = 30/163 (18%)

Query: 537  TRPSTEEPVRRPQRPRSPPLPAVIRNAPSRPPS----LPTPRPASQPRKAPVISSTPKLP 592
            T P TEE       P  P  PA   +AP  P +    + TP   + P  A      P  P
Sbjct: 961  TVPITEED----GTPEGPVTPATTVHAPEEPDTAAVRVSTPEEPASPAAAVPTPEEPTSP 1016

Query: 593  ALAAREEASTSRLLQPPEAPRKPANTLVKTASRPAPLVQQLSPSLLPNSKSPRE----VP 648
            A A          +  PE P  PA      A+ P P       + +P  + P      VP
Sbjct: 1017 AAA----------VPTPEEPTSPA------AAVPPPEEPTSPAAAVPTPEEPTSPAAAVP 1060

Query: 649  SPKVIKTP--VVKKTESPIKLSPATPSRKRSVAVSDEEEVEEE 689
            +P+   +P   V   E P   + A P+ +   + +      EE
Sbjct: 1061 TPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEE 1103



 Score = 33.1 bits (74), Expect = 1.3
 Identities = 37/142 (26%), Positives = 57/142 (40%), Gaps = 15/142 (10%)

Query: 545  VRRPQRPRSP----PLPAVIRNAPSRPPSL--PTPRPASQPRKAPVISSTPKLPALAA-- 596
            V  P+   SP    P PA   +  +   +L  PT   AS P  A ++++  +  + AA  
Sbjct: 1163 VPTPEESASPAAAVPTPAESASFAAVVATLEEPTSPAASVPTPAAMVATLEEFTSPAASV 1222

Query: 597  ---REEASTSRLLQPPEAPRKPANTLVKTASRPAPLVQQLSPSLLPNSKSPREVPSPKVI 653
                E AS +  +  PE P  PA  +       +     L+P  L  S     VP+P+  
Sbjct: 1223 PTSEEPASLAAAVSNPEEPTSPAAAVPTLEEPTSSAAAVLTPEEL--SSPAASVPTPEEP 1280

Query: 654  KTP--VVKKTESPIKLSPATPS 673
             +P   V   E P   + A P+
Sbjct: 1281 ASPAAAVSNLEEPASPAAAVPT 1302


>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo
           sapiens]
          Length = 1124

 Score = 48.5 bits (114), Expect = 3e-05
 Identities = 46/141 (32%), Positives = 61/141 (43%), Gaps = 9/141 (6%)

Query: 519 TTPIRSQADLKKLPLEVTTRPSTEEPVRRPQRP--RSPPLPAV--IRNAPSRPPSLPTPR 574
           T P ++   L   PL+V   P    P+     P  R PPL A   ++  PS P SLP   
Sbjct: 721 TPPPQAPPPLAAPPLQVPPSPPASPPMSPSATPPPRVPPLLAAPPLQVPPSPPASLPMSP 780

Query: 575 PASQPRKAPVISSTPKLPALAAREEASTSRLLQPPEA--PRKPANTLVKTAS--RPAPLV 630
            A  P +AP   +TP L AL +   +   +    P A  P  P  T    A     APL+
Sbjct: 781 LAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLL 840

Query: 631 Q-QLSPSLLPNSKSPREVPSP 650
           Q   SP   P  ++PR  P+P
Sbjct: 841 QVPPSPPASPTLQAPRRPPTP 861



 Score = 45.4 bits (106), Expect = 3e-04
 Identities = 44/166 (26%), Positives = 64/166 (38%), Gaps = 13/166 (7%)

Query: 519 TTPIRSQADLKKLPLEVTTRPSTEEPVRRPQRPRSPPLPAVIRNAPSRPPSLPTPRPASQ 578
           T P+ +   L   PL+  + P T   +  P  P   PL A      + PP  P+      
Sbjct: 532 TPPLENLPSLAPPPLQTASAPLTTPHLETPPCPAPCPLQAPPSPLTTPPPETPSSIATPP 591

Query: 579 PRKAPVISS-------TPKLPALAAREEASTSRLLQPP--EAPRKPANTLVKTASRPAPL 629
           P+  P ++S       +P L  LA     +   L  PP    P  PA+  +   + P+P 
Sbjct: 592 PQAPPALASPPLQGLPSPPLSPLATPPPQAPPXLALPPLQAPPSPPASPPLSPLATPSPQ 651

Query: 630 V-QQLSPSLLPNSKSPREVPSPKVIKTPVVKKTESPIKLSPATPSR 674
               L+  LL    SP   PSP V + P       P+  S   PS+
Sbjct: 652 APNALAVHLLQAPFSP--PPSPPV-QAPFSPPASPPVSPSATPPSQ 694



 Score = 44.7 bits (104), Expect = 4e-04
 Identities = 47/152 (30%), Positives = 62/152 (40%), Gaps = 17/152 (11%)

Query: 532 PLEVTTRPSTEEP----VRRPQRPRSPPLPAVIRNAPSRPPSLPTPRP-ASQPRKAPVIS 586
           PL     PS + P    V   Q P SPP P+    AP  PP+ P   P A+ P +AP   
Sbjct: 641 PLSPLATPSPQAPNALAVHLLQAPFSPP-PSPPVQAPFSPPASPPVSPSATPPSQAPPSL 699

Query: 587 STPKL---PALAAREEASTSRLLQPPEAPRKPANTLVKTASRPAPLVQQLSPSLLPNSKS 643
           + P L   P+  A    S S    P   P   A  L    S PA      SP + P++  
Sbjct: 700 AAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQVPPSPPA------SPPMSPSATP 753

Query: 644 PREVPSPKVIKTPVVKKTESPIKLSPATPSRK 675
           P  V  P ++  P ++   SP    P +P  K
Sbjct: 754 PPRV--PPLLAAPPLQVPPSPPASLPMSPLAK 783



 Score = 43.9 bits (102), Expect = 7e-04
 Identities = 48/176 (27%), Positives = 70/176 (39%), Gaps = 35/176 (19%)

Query: 518 KTTPIRSQADLKKLPLEVTTRP-------STEEPVRRP-------QRPRSPPLPAVIRNA 563
           +T P  +   L+  P  +TT P       +T  P   P       Q   SPPL  +    
Sbjct: 559 ETPPCPAPCPLQAPPSPLTTPPPETPSSIATPPPQAPPALASPPLQGLPSPPLSPLATPP 618

Query: 564 PSRPPSLPTP------RPASQPRKAPVISSTPKLPALAAREEASTSRLLQPPEAPRKPAN 617
           P  PP L  P       P + P  +P+ + +P+ P       A    LLQ P +P  P +
Sbjct: 619 PQAPPXLALPPLQAPPSPPASPPLSPLATPSPQAP------NALAVHLLQAPFSP--PPS 670

Query: 618 TLVKTASRPAPLVQQLSPSLLPNSKSPREVPSPKVIKTPVVKKTESPIKLSPATPS 673
             V+    P P    +SPS  P S++P  + +P +   P      SP    P +PS
Sbjct: 671 PPVQAPFSP-PASPPVSPSATPPSQAPPSLAAPPLQVPP------SPPASPPMSPS 719



 Score = 42.4 bits (98), Expect = 0.002
 Identities = 43/151 (28%), Positives = 61/151 (40%), Gaps = 24/151 (15%)

Query: 540 STEEPVRRPQRPRSPPLPAVIRNAPSRPPSLPTPRPASQPRKAPVISSTPKLPALAAREE 599
           ST EP   P   R P     ++   SR  S      +S  R  P    TP+ PA  ++ +
Sbjct: 216 STTEP--SPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPK 273

Query: 600 ASTSRLLQPPEA--PRKPANTLVKTASRPAPLVQQLSPSLL----PNSKSPREVPSPKVI 653
               + L+PP+   PRK A          AP +  LS S L    P+    R VP P   
Sbjct: 274 PKGLQALRPPQVTPPRKDA----------APALGPLSSSPLATPSPSGTKARPVPPPDNA 323

Query: 654 KTPV------VKKTESPIKLSPATPSRKRSV 678
            TP+           +P+ L+P +PS   S+
Sbjct: 324 ATPLPATLPPSPPLATPLPLAPPSPSAPPSL 354



 Score = 41.2 bits (95), Expect = 0.005
 Identities = 52/184 (28%), Positives = 78/184 (42%), Gaps = 30/184 (16%)

Query: 513 LEALQKTTPIRSQADLKKLPLEVTTRP-STEEPVRRPQRPR-----SPPLPAVIRNAPSR 566
           L +LQ TT + S   L+     +T  P  T+  +  P RP      SPPL A + + P+ 
Sbjct: 409 LSSLQATTSLGSPT-LQATHSFLTMSPRQTQASLTSPSRPASTPPDSPPLQAPL-SLPAS 466

Query: 567 PPSLPTPRPASQPRKAPV-ISSTPKLPALAARE-EASTSRLLQPP---EAPRKPANTLVK 621
           PP   +  PA  P  +P+ I     L +LA+   +A  S L+ PP   ++   P +    
Sbjct: 467 PPLQTSLSPAVSPLSSPLTIHPLQALSSLASHSPQAPLSSLIMPPLETQSSLAPPSLQTP 526

Query: 622 TAS------------RPAPLVQQLSPSLLPNSKSPREVPSPKVIKTPVVKKTESPIKLSP 669
            AS             P PL    +P   P+ ++P   P+P  ++ P    T  P    P
Sbjct: 527 PASLTTPPLENLPSLAPPPLQTASAPLTTPHLETP-PCPAPCPLQAPPSPLTTPP----P 581

Query: 670 ATPS 673
            TPS
Sbjct: 582 ETPS 585



 Score = 40.8 bits (94), Expect = 0.006
 Identities = 45/169 (26%), Positives = 67/169 (39%), Gaps = 24/169 (14%)

Query: 532 PLEVTTRPSTEEPVRRP--QRPRSPPLPAVIRNAPSRPP-SLPTPRPASQPRKAPVISST 588
           P +VT       P   P    P + P P+  +  P  PP +  TP PA+ P   P+ +  
Sbjct: 282 PPQVTPPRKDAAPALGPLSSSPLATPSPSGTKARPVPPPDNAATPLPATLPPSPPLATPL 341

Query: 589 PKLPALAAREEASTSRLLQPPEAPRKPANTLVKTASRPA-PLVQQLSPSLLPN---SKSP 644
           P  P  +     S   L  PP  P   A   + T    A P +Q + P  +P+   S S 
Sbjct: 342 PLAPP-SPSAPPSLQTLPSPPATPPSQAPPSMTTPPMQAPPSLQTIPPIQVPHSLTSPSL 400

Query: 645 REVPSPKVIK---------TPVVKKTESPIKLSP-------ATPSRKRS 677
           +  PSP  +          +P ++ T S + +SP        +PSR  S
Sbjct: 401 QAPPSPLALSSLQATTSLGSPTLQATHSFLTMSPRQTQASLTSPSRPAS 449



 Score = 39.7 bits (91), Expect = 0.014
 Identities = 42/169 (24%), Positives = 68/169 (40%), Gaps = 21/169 (12%)

Query: 519 TTPIRSQADLKKLPLEVTTRPSTEEPVRRPQRPRSPPLPAVIRNAPSR-PPSLPTPRPAS 577
           T P ++   L   PL+V   P    P+  P     P  P  +   P + PPS P   P S
Sbjct: 690 TPPSQAPPSLAAPPLQVPPSPPASPPMS-PSATPPPQAPPPLAAPPLQVPPSPPASPPMS 748

Query: 578 -----QPRKAPVISSTP-KLPALAAREEASTSRLLQPPEAPRKPANTLVKTASRP----- 626
                 PR  P++++ P ++P         +     PP+AP   A   ++    P     
Sbjct: 749 PSATPPPRVPPLLAAPPLQVPPSPPASLPMSPLAKPPPQAPPALATPPLQALPSPPASFP 808

Query: 627 --APLVQQLSPSLLPNSKSPREVPSPKVIKTPVVKKTESPIKLSPATPS 673
             AP     S  + P +  P +  +P V+  P+++   SP    PA+P+
Sbjct: 809 GQAPFSPSASLPMSPLATPPPQ--APPVLAAPLLQVPPSP----PASPT 851



 Score = 35.8 bits (81), Expect = 0.20
 Identities = 44/162 (27%), Positives = 55/162 (33%), Gaps = 29/162 (17%)

Query: 539 PSTEEPVRRPQRPRSPPLPAVIRNAPSRPPSLPTPRPASQPRKAPVISSTPKLPALAARE 598
           P T  P    +   +     + R APS  P  PT  P      A   S+T   PA   R 
Sbjct: 169 PGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRP 228

Query: 599 EA--------------STSRLLQP----------PEAPRKPANTLVK--TASRP---APL 629
            A              S + L  P          P AP  P+    K   A RP    P 
Sbjct: 229 SAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPP 288

Query: 630 VQQLSPSLLPNSKSPREVPSPKVIKTPVVKKTESPIKLSPAT 671
            +  +P+L P S SP   PSP   K   V   ++     PAT
Sbjct: 289 RKDAAPALGPLSSSPLATPSPSGTKARPVPPPDNAATPLPAT 330



 Score = 33.9 bits (76), Expect = 0.76
 Identities = 41/140 (29%), Positives = 57/140 (40%), Gaps = 20/140 (14%)

Query: 558 AVIRNAPSRPPSLPTPRPASQPRKAPVISSTPKLPALAAREEASTSRLLQPPEAPRK--- 614
           A  R   +R P L TPRP   PR  P     P  PA A R   +   + + P A R    
Sbjct: 12  AAARTPAARAPGLLTPRPPGSPRPPP-----PVTPA-ALRVLGAAGAVGRKPLAERAGGI 65

Query: 615 PANTLVKTASRPAPLVQQLSPSLLPNSKSPREVPSPKVIKTPVVKKT-----ESPIKLSP 669
              T+ ++A R  P     + S  P S+ P    S +  + P  K T      SP + S 
Sbjct: 66  GGATIPESAPRAGPTRSAGTSSRNPASRPP---ASGRGERAPPAKNTSPGPVSSPGRASG 122

Query: 670 AT---PSRKRSVAVSDEEEV 686
            T   P  ++ + +S EE V
Sbjct: 123 TTRPGPLGQKGLRISAEETV 142



 Score = 33.5 bits (75), Expect = 0.99
 Identities = 40/134 (29%), Positives = 55/134 (41%), Gaps = 25/134 (18%)

Query: 548 PQRPRSPPL-PAVIRNAPSRPPSLPTPRPASQPRKAPVISSTPKL--PALAAREEASTSR 604
           PQ P S  + P +   +   PPSL TP PAS     P + + P L  P L       T+ 
Sbjct: 500 PQAPLSSLIMPPLETQSSLAPPSLQTP-PAS--LTTPPLENLPSLAPPPLQTASAPLTTP 556

Query: 605 LLQPPEAPRKPANTLVKTASRPAPLVQQLSPSLLPNSKSPREV-----PSPKVIKTPVVK 659
            L+ P  P             P PL    SP   P  ++P  +      +P  + +P ++
Sbjct: 557 HLETPPCP------------APCPLQAPPSPLTTPPPETPSSIATPPPQAPPALASPPLQ 604

Query: 660 KTESPIKLSP-ATP 672
              SP  LSP ATP
Sbjct: 605 GLPSP-PLSPLATP 617


>gi|21312134 mediator complex subunit 15 isoform b [Homo sapiens]
          Length = 748

 Score = 48.5 bits (114), Expect = 3e-05
 Identities = 62/264 (23%), Positives = 99/264 (37%), Gaps = 65/264 (24%)

Query: 495 QEEKQKQLTEKIRQQQEKLEALQKTTPIRSQADLKKLPLEVTTRPSTEEPVRRPQRPRSP 554
           Q + Q+Q  ++ +QQQ++ +ALQ   PI+     +  P      P   + +   Q  + P
Sbjct: 243 QLQLQQQQQQQQQQQQQQQQALQAQPPIQQPPMQQPQPPPSQALPQQLQQMHHTQHHQPP 302

Query: 555 PLPA---VIRNAPSR-PPSLPTPRPASQPR----------------KAPVI--------- 585
           P P    V +N PS+ PP   T    SQ +                +AP++         
Sbjct: 303 PQPQQPPVAQNQPSQLPPQSQTQPLVSQAQALPGQMLYTQPPLKFVRAPMVVQQPPVQPQ 362

Query: 586 -------------------------SSTPKLPALAAREEASTSRLLQPPEAP-----RKP 615
                                    SS P L + +  ++  T + + PP  P     +  
Sbjct: 363 VQQQQTAVQTAQAAQMVAPGVQVSQSSLPMLSSPSPGQQVQTPQSMPPPPQPSPQPGQPS 422

Query: 616 ANTLVKTASRPAPLVQQLSPSLLPNSKSPREVPSPKVIKTPVVKKTESPIKL-SPATPSR 674
           +      +S PAP     SPS    S SP+   SP   +TP      SP  L +P  PS 
Sbjct: 423 SQPNSNVSSGPAP-----SPSSFLPSPSPQPSQSPVTARTPQNFSVPSPGPLNTPVNPSS 477

Query: 675 KRSVAVSDEEEVEEEAERRKERCK 698
             S A S + E ++  ++ K+  K
Sbjct: 478 VMSPAGSSQAEEQQYLDKLKQLSK 501



 Score = 43.9 bits (102), Expect = 7e-04
 Identities = 74/366 (20%), Positives = 140/366 (38%), Gaps = 52/366 (14%)

Query: 363 HNKQDFADAKEYRHLLRAMGEHLAQYWKDIAIAQRGIIKFWDEFGYLSA-------NWNQ 415
           HNK+  A   +  + L+++    A     I +  RG  +     G L A       +   
Sbjct: 70  HNKKSQASVSDPMNALQSLTGGPAAGAAGIGMPPRGPGQSLGGMGSLGAMGQPMSLSGQP 129

Query: 416 PPSSELRYKRRRAMEIPTTIQCDLCLKWRTLPFQLSSVEKDYPDTWVCSMNPDPEQDRCE 475
           PP +        A+    T Q  L L+   L  Q    ++ +      ++    +Q + +
Sbjct: 130 PPGTSGMAPHSMAVVSTATPQTQLQLQQVAL--QQQQQQQQFQQQQQAALQQQQQQQQQQ 187

Query: 476 ASEQKQKVPLGTFRKDMKTQEEKQKQLTEK-------------IRQQQEKLE-----ALQ 517
             + +Q      F+  ++ Q++ Q+Q  ++             I+QQQ++L+      LQ
Sbjct: 188 QFQAQQSAMQQQFQAVVQQQQQLQQQQQQQQHLIKLHHQNQQQIQQQQQQLQRIAQLQLQ 247

Query: 518 KTTPIRSQADLKKLPLEVTTRPSTEEPVRRPQRPRSPPLPAVIRNAPSRPPSLPTPRP-- 575
           +    + Q   ++        P  + P+++PQ P S  LP  ++         P P+P  
Sbjct: 248 QQQQQQQQQQQQQQQALQAQPPIQQPPMQQPQPPPSQALPQQLQQMHHTQHHQPPPQPQQ 307

Query: 576 ----ASQPRKAPVISSTPKLPALAAREEASTSRLL--QPP-----------EAPRKPANT 618
                +QP + P  S T     L ++ +A   ++L  QPP           + P +P   
Sbjct: 308 PPVAQNQPSQLPPQSQT---QPLVSQAQALPGQMLYTQPPLKFVRAPMVVQQPPVQPQVQ 364

Query: 619 LVKTASRPAPLVQQLSPSLLPNSKSPREVPSP---KVIKTPVVKKTESPIKLSPATPSRK 675
             +TA + A   Q ++P +  +  S   + SP   + ++TP            P  PS +
Sbjct: 365 QQQTAVQTAQAAQMVAPGVQVSQSSLPMLSSPSPGQQVQTPQSMPPPPQPSPQPGQPSSQ 424

Query: 676 RSVAVS 681
            +  VS
Sbjct: 425 PNSNVS 430



 Score = 43.9 bits (102), Expect = 7e-04
 Identities = 30/119 (25%), Positives = 52/119 (43%), Gaps = 15/119 (12%)

Query: 484 PLGTFRKDMKTQEEKQKQLTEKIRQQQEKLEALQKTTPIRSQADLKKLPLEVTTRPSTEE 543
           PL   R  M  Q   Q  +  +++QQQ  ++  Q    +     + +  L + + PS  +
Sbjct: 344 PLKFVRAPMVVQ---QPPVQPQVQQQQTAVQTAQAAQMVAPGVQVSQSSLPMLSSPSPGQ 400

Query: 544 PVRRPQRPRSPPLPAV------------IRNAPSRPPSLPTPRPASQPRKAPVISSTPK 590
            V+ PQ    PP P+             + + P+  PS   P P+ QP ++PV + TP+
Sbjct: 401 QVQTPQSMPPPPQPSPQPGQPSSQPNSNVSSGPAPSPSSFLPSPSPQPSQSPVTARTPQ 459


>gi|239751395 PREDICTED: hypothetical protein, partial [Homo
           sapiens]
          Length = 306

 Score = 48.1 bits (113), Expect = 4e-05
 Identities = 42/142 (29%), Positives = 57/142 (40%), Gaps = 11/142 (7%)

Query: 536 TTRPSTEEPVRRPQRPR----SPPLPAVIRNAPSRPPSLPTPRPASQPRKAPVISSTPKL 591
           T  PS++  + R   P     SPP           P + PT  P+S P   P  SSTP L
Sbjct: 25  TLTPSSQPILTRSSTPTLTPSSPPTLTPSNTPTLTPSNTPTLTPSSTPTLTP--SSTPTL 82

Query: 592 PALAAREEASTSRLLQPPEAPRKPANTLVKTASRPAPLVQQLSPSLLPNSKSPREVPSPK 651
                   +ST  L         P+NT   T S    L    +P+L P+S +P   PS  
Sbjct: 83  TPQPILTRSSTPTLTPSSPPTLTPSNTPTLTPSNTPTLTPSNTPTLTPSS-TPTLTPS-- 139

Query: 652 VIKTPVVKKTESPIKLSPATPS 673
              TP +  +  PI    +TP+
Sbjct: 140 --STPTLTPSSRPILTRSSTPT 159



 Score = 42.7 bits (99), Expect = 0.002
 Identities = 45/144 (31%), Positives = 59/144 (40%), Gaps = 9/144 (6%)

Query: 536 TTRPSTEEPVRRPQRPRSPPLPAVIRNAPSRPP----SLPTPRPASQPRKAPVISSTPKL 591
           T  PS+   + R   P   P    I    S P     S PT  P+S P   P  SSTP L
Sbjct: 143 TLTPSSRPILTRSSTPTLTPSSRPILTRSSTPTLTPSSTPTLTPSSTPTLTP--SSTPTL 200

Query: 592 -PALAAREEASTSRLLQPPEAP-RKPANTLVKTASRPAPLVQQLSPSLLPNSKSPREVPS 649
            P+       S++  L P   P   P++T   T S    L +  +P+L P+S +P   PS
Sbjct: 201 TPSSRPILTRSSTPTLTPSSRPILTPSSTPTLTPSSRPILTRSSTPTLTPSS-TPTLTPS 259

Query: 650 PKVIKTPVVKKTESPIKLSPATPS 673
                TP    T +P      TPS
Sbjct: 260 NTPTLTPSNTPTLTPSNTPTLTPS 283



 Score = 42.0 bits (97), Expect = 0.003
 Identities = 39/127 (30%), Positives = 51/127 (40%), Gaps = 16/127 (12%)

Query: 564 PSRPPSL-PTPRPASQPRKAPVI--SSTPKLPALAAREEASTSRLLQPPEAPR-KPANTL 619
           PS PP+L P+  P   P   P++  SSTP L         S+   L P   P   P+NT 
Sbjct: 12  PSSPPTLTPSSTPTLTPSSQPILTRSSTPTLTP-------SSPPTLTPSNTPTLTPSNTP 64

Query: 620 VKTASRPAPLVQQLSPSLLPN-----SKSPREVPSPKVIKTPVVKKTESPIKLSPATPSR 674
             T S    L    +P+L P      S +P   PS     TP    T +P      TPS 
Sbjct: 65  TLTPSSTPTLTPSSTPTLTPQPILTRSSTPTLTPSSPPTLTPSNTPTLTPSNTPTLTPSN 124

Query: 675 KRSVAVS 681
             ++  S
Sbjct: 125 TPTLTPS 131



 Score = 42.0 bits (97), Expect = 0.003
 Identities = 39/141 (27%), Positives = 53/141 (37%), Gaps = 11/141 (7%)

Query: 536 TTRPSTEEPVRRPQRPRSPPLPAVIRNAPSRPPSLPTPRPASQPRKAPVI--SSTPKLPA 593
           T  PS+   + R   P   P         S P   P+  P   P   P++  SSTP L  
Sbjct: 159 TLTPSSRPILTRSSTPTLTPSSTPTLTPSSTPTLTPSSTPTLTPSSRPILTRSSTPTLTP 218

Query: 594 LAAREEASTSRLLQPPEAPR-KPANTLVKTASRPAPLVQQLSPSLLPNSKSPREVPSPKV 652
                  S+  +L P   P   P++  + T S    L    +P+L P S +P   PS   
Sbjct: 219 -------SSRPILTPSSTPTLTPSSRPILTRSSTPTLTPSSTPTLTP-SNTPTLTPSNTP 270

Query: 653 IKTPVVKKTESPIKLSPATPS 673
             TP    T +P      TPS
Sbjct: 271 TLTPSNTPTLTPSSTPTLTPS 291



 Score = 41.2 bits (95), Expect = 0.005
 Identities = 41/149 (27%), Positives = 59/149 (39%), Gaps = 17/149 (11%)

Query: 536 TTRPSTEEPVRRPQRPRSPPLPAVIRNA-----PSRPPSL-PTPRPASQPRKAPVI--SS 587
           T  PS+   +     P   P P + R++     PS PP+L P+  P   P   P +  S+
Sbjct: 65  TLTPSSTPTLTPSSTPTLTPQPILTRSSTPTLTPSSPPTLTPSNTPTLTPSNTPTLTPSN 124

Query: 588 TPKLPALAAREEASTSRLLQPPEAPR-KPANTLVKTASRPAPLVQQLSPSLLPNSKSPRE 646
           TP L         S++  L P   P   P++  + T S    L     P +L  S +P  
Sbjct: 125 TPTLTP-------SSTPTLTPSSTPTLTPSSRPILTRSSTPTLTPSSRP-ILTRSSTPTL 176

Query: 647 VPSPKVIKTPVVKKTESPIKLSPATPSRK 675
            PS     TP    T +P      TPS +
Sbjct: 177 TPSSTPTLTPSSTPTLTPSSTPTLTPSSR 205



 Score = 40.8 bits (94), Expect = 0.006
 Identities = 33/108 (30%), Positives = 52/108 (48%), Gaps = 12/108 (11%)

Query: 567 PPSLPTPRPASQPRKAPVISSTPKL-PALAAREEASTSRLLQPPEAPR-KPANTLVKTAS 624
           P + PT  P+S P   P  SSTP L P+       S++  L P   P   P+NT   T S
Sbjct: 4   PSNTPTLTPSSPPTLTP--SSTPTLTPSSQPILTRSSTPTLTPSSPPTLTPSNTPTLTPS 61

Query: 625 RPAPLVQQLSPSLLPNSKSPREVPSPKVIKTPVVKKTESPIKLSPATP 672
               L    +P+L P+S       +P +   P++ ++ +P  L+P++P
Sbjct: 62  NTPTLTPSSTPTLTPSS-------TPTLTPQPILTRSSTP-TLTPSSP 101



 Score = 40.8 bits (94), Expect = 0.006
 Identities = 46/153 (30%), Positives = 64/153 (41%), Gaps = 16/153 (10%)

Query: 532 PLEVTTRPSTEEPVRRPQRPRSPPLPAVIRNAPSRPPSL-----PTPRPASQPRKAPVIS 586
           P  + TR ST  P   P  P +          PS  P+L     PT  P+S P   P  S
Sbjct: 84  PQPILTRSST--PTLTPSSPPTLTPSNTPTLTPSNTPTLTPSNTPTLTPSSTPTLTP--S 139

Query: 587 STPKL-PALAAREEASTSRLLQPPEAP-RKPANTLVKTASRPAPLVQQLSPSLLPNSKSP 644
           STP L P+       S++  L P   P    ++T   T S    L    +P+L P+S +P
Sbjct: 140 STPTLTPSSRPILTRSSTPTLTPSSRPILTRSSTPTLTPSSTPTLTPSSTPTLTPSS-TP 198

Query: 645 REVPSPKVI----KTPVVKKTESPIKLSPATPS 673
              PS + I     TP +  +  PI    +TP+
Sbjct: 199 TLTPSSRPILTRSSTPTLTPSSRPILTPSSTPT 231



 Score = 39.7 bits (91), Expect = 0.014
 Identities = 40/127 (31%), Positives = 52/127 (40%), Gaps = 9/127 (7%)

Query: 536 TTRPSTEEPVRRPQRPRSPPLPAVIRNAPSRP----PSLPTPRPASQPRKAPVISSTPKL 591
           T  PS+   +     P   P         SRP     S PT  P+S+P   P  SSTP L
Sbjct: 175 TLTPSSTPTLTPSSTPTLTPSSTPTLTPSSRPILTRSSTPTLTPSSRPILTP--SSTPTL 232

Query: 592 -PALAAREEASTSRLLQPPEAPR-KPANTLVKTASRPAPLVQQLSPSLLPNSKSPREVPS 649
            P+       S++  L P   P   P+NT   T S    L    +P+L P+S +P   PS
Sbjct: 233 TPSSRPILTRSSTPTLTPSSTPTLTPSNTPTLTPSNTPTLTPSNTPTLTPSS-TPTLTPS 291

Query: 650 PKVIKTP 656
                TP
Sbjct: 292 STPTLTP 298



 Score = 39.3 bits (90), Expect = 0.018
 Identities = 40/151 (26%), Positives = 57/151 (37%), Gaps = 5/151 (3%)

Query: 536 TTRPSTEEPVRRPQRPRSPPLPAVIRNAPSRPPSLPTPRPASQPRKAPVI--SSTPKL-P 592
           T  PS    +     P   P         SRP    +  P   P   P++  SSTP L P
Sbjct: 119 TLTPSNTPTLTPSSTPTLTPSSTPTLTPSSRPILTRSSTPTLTPSSRPILTRSSTPTLTP 178

Query: 593 ALAAREEASTSRLLQPPEAPR-KPANTLVKTASRPAPLVQQLSPSLLPNSKSPREVPSPK 651
           +       S++  L P   P   P++  + T S    L     P L P+S +P   PS +
Sbjct: 179 SSTPTLTPSSTPTLTPSSTPTLTPSSRPILTRSSTPTLTPSSRPILTPSS-TPTLTPSSR 237

Query: 652 VIKTPVVKKTESPIKLSPATPSRKRSVAVSD 682
            I T     T +P      TPS   ++  S+
Sbjct: 238 PILTRSSTPTLTPSSTPTLTPSNTPTLTPSN 268



 Score = 37.4 bits (85), Expect = 0.069
 Identities = 33/110 (30%), Positives = 44/110 (40%), Gaps = 12/110 (10%)

Query: 536 TTRPSTEEPVRRPQRPRSPPLPAVIRNAPSRPPSLPTPRPASQPRKAPVI--SSTPKL-P 592
           T  PS+   + R   P   P         SRP   P+  P   P   P++  SSTP L P
Sbjct: 199 TLTPSSRPILTRSSTPTLTP--------SSRPILTPSSTPTLTPSSRPILTRSSTPTLTP 250

Query: 593 ALAAREEASTSRLLQPPEAPR-KPANTLVKTASRPAPLVQQLSPSLLPNS 641
           +       S +  L P   P   P+NT   T S    L    +P+L P+S
Sbjct: 251 SSTPTLTPSNTPTLTPSNTPTLTPSNTPTLTPSSTPTLTPSSTPTLTPSS 300


>gi|239745904 PREDICTED: hypothetical protein, partial [Homo
           sapiens]
          Length = 306

 Score = 48.1 bits (113), Expect = 4e-05
 Identities = 42/142 (29%), Positives = 57/142 (40%), Gaps = 11/142 (7%)

Query: 536 TTRPSTEEPVRRPQRPR----SPPLPAVIRNAPSRPPSLPTPRPASQPRKAPVISSTPKL 591
           T  PS++  + R   P     SPP           P + PT  P+S P   P  SSTP L
Sbjct: 25  TLTPSSQPILTRSSTPTLTPSSPPTLTPSNTPTLTPSNTPTLTPSSTPTLTP--SSTPTL 82

Query: 592 PALAAREEASTSRLLQPPEAPRKPANTLVKTASRPAPLVQQLSPSLLPNSKSPREVPSPK 651
                   +ST  L         P+NT   T S    L    +P+L P+S +P   PS  
Sbjct: 83  TPQPILTRSSTPTLTPSSPPTLTPSNTPTLTPSNTPTLTPSNTPTLTPSS-TPTLTPS-- 139

Query: 652 VIKTPVVKKTESPIKLSPATPS 673
              TP +  +  PI    +TP+
Sbjct: 140 --STPTLTPSSRPILTRSSTPT 159



 Score = 42.7 bits (99), Expect = 0.002
 Identities = 45/144 (31%), Positives = 59/144 (40%), Gaps = 9/144 (6%)

Query: 536 TTRPSTEEPVRRPQRPRSPPLPAVIRNAPSRPP----SLPTPRPASQPRKAPVISSTPKL 591
           T  PS+   + R   P   P    I    S P     S PT  P+S P   P  SSTP L
Sbjct: 143 TLTPSSRPILTRSSTPTLTPSSRPILTRSSTPTLTPSSTPTLTPSSTPTLTP--SSTPTL 200

Query: 592 -PALAAREEASTSRLLQPPEAP-RKPANTLVKTASRPAPLVQQLSPSLLPNSKSPREVPS 649
            P+       S++  L P   P   P++T   T S    L +  +P+L P+S +P   PS
Sbjct: 201 TPSSRPILTRSSTPTLTPSSRPILTPSSTPTLTPSSRPILTRSSTPTLTPSS-TPTLTPS 259

Query: 650 PKVIKTPVVKKTESPIKLSPATPS 673
                TP    T +P      TPS
Sbjct: 260 NTPTLTPSNTPTLTPSNTPTLTPS 283



 Score = 42.0 bits (97), Expect = 0.003
 Identities = 39/127 (30%), Positives = 51/127 (40%), Gaps = 16/127 (12%)

Query: 564 PSRPPSL-PTPRPASQPRKAPVI--SSTPKLPALAAREEASTSRLLQPPEAPR-KPANTL 619
           PS PP+L P+  P   P   P++  SSTP L         S+   L P   P   P+NT 
Sbjct: 12  PSSPPTLTPSSTPTLTPSSQPILTRSSTPTLTP-------SSPPTLTPSNTPTLTPSNTP 64

Query: 620 VKTASRPAPLVQQLSPSLLPN-----SKSPREVPSPKVIKTPVVKKTESPIKLSPATPSR 674
             T S    L    +P+L P      S +P   PS     TP    T +P      TPS 
Sbjct: 65  TLTPSSTPTLTPSSTPTLTPQPILTRSSTPTLTPSSPPTLTPSNTPTLTPSNTPTLTPSN 124

Query: 675 KRSVAVS 681
             ++  S
Sbjct: 125 TPTLTPS 131



 Score = 42.0 bits (97), Expect = 0.003
 Identities = 39/141 (27%), Positives = 53/141 (37%), Gaps = 11/141 (7%)

Query: 536 TTRPSTEEPVRRPQRPRSPPLPAVIRNAPSRPPSLPTPRPASQPRKAPVI--SSTPKLPA 593
           T  PS+   + R   P   P         S P   P+  P   P   P++  SSTP L  
Sbjct: 159 TLTPSSRPILTRSSTPTLTPSSTPTLTPSSTPTLTPSSTPTLTPSSRPILTRSSTPTLTP 218

Query: 594 LAAREEASTSRLLQPPEAPR-KPANTLVKTASRPAPLVQQLSPSLLPNSKSPREVPSPKV 652
                  S+  +L P   P   P++  + T S    L    +P+L P S +P   PS   
Sbjct: 219 -------SSRPILTPSSTPTLTPSSRPILTRSSTPTLTPSSTPTLTP-SNTPTLTPSNTP 270

Query: 653 IKTPVVKKTESPIKLSPATPS 673
             TP    T +P      TPS
Sbjct: 271 TLTPSNTPTLTPSSTPTLTPS 291



 Score = 41.2 bits (95), Expect = 0.005
 Identities = 41/149 (27%), Positives = 59/149 (39%), Gaps = 17/149 (11%)

Query: 536 TTRPSTEEPVRRPQRPRSPPLPAVIRNA-----PSRPPSL-PTPRPASQPRKAPVI--SS 587
           T  PS+   +     P   P P + R++     PS PP+L P+  P   P   P +  S+
Sbjct: 65  TLTPSSTPTLTPSSTPTLTPQPILTRSSTPTLTPSSPPTLTPSNTPTLTPSNTPTLTPSN 124

Query: 588 TPKLPALAAREEASTSRLLQPPEAPR-KPANTLVKTASRPAPLVQQLSPSLLPNSKSPRE 646
           TP L         S++  L P   P   P++  + T S    L     P +L  S +P  
Sbjct: 125 TPTLTP-------SSTPTLTPSSTPTLTPSSRPILTRSSTPTLTPSSRP-ILTRSSTPTL 176

Query: 647 VPSPKVIKTPVVKKTESPIKLSPATPSRK 675
            PS     TP    T +P      TPS +
Sbjct: 177 TPSSTPTLTPSSTPTLTPSSTPTLTPSSR 205



 Score = 40.8 bits (94), Expect = 0.006
 Identities = 33/108 (30%), Positives = 52/108 (48%), Gaps = 12/108 (11%)

Query: 567 PPSLPTPRPASQPRKAPVISSTPKL-PALAAREEASTSRLLQPPEAPR-KPANTLVKTAS 624
           P + PT  P+S P   P  SSTP L P+       S++  L P   P   P+NT   T S
Sbjct: 4   PSNTPTLTPSSPPTLTP--SSTPTLTPSSQPILTRSSTPTLTPSSPPTLTPSNTPTLTPS 61

Query: 625 RPAPLVQQLSPSLLPNSKSPREVPSPKVIKTPVVKKTESPIKLSPATP 672
               L    +P+L P+S       +P +   P++ ++ +P  L+P++P
Sbjct: 62  NTPTLTPSSTPTLTPSS-------TPTLTPQPILTRSSTP-TLTPSSP 101



 Score = 40.8 bits (94), Expect = 0.006
 Identities = 46/153 (30%), Positives = 64/153 (41%), Gaps = 16/153 (10%)

Query: 532 PLEVTTRPSTEEPVRRPQRPRSPPLPAVIRNAPSRPPSL-----PTPRPASQPRKAPVIS 586
           P  + TR ST  P   P  P +          PS  P+L     PT  P+S P   P  S
Sbjct: 84  PQPILTRSST--PTLTPSSPPTLTPSNTPTLTPSNTPTLTPSNTPTLTPSSTPTLTP--S 139

Query: 587 STPKL-PALAAREEASTSRLLQPPEAP-RKPANTLVKTASRPAPLVQQLSPSLLPNSKSP 644
           STP L P+       S++  L P   P    ++T   T S    L    +P+L P+S +P
Sbjct: 140 STPTLTPSSRPILTRSSTPTLTPSSRPILTRSSTPTLTPSSTPTLTPSSTPTLTPSS-TP 198

Query: 645 REVPSPKVI----KTPVVKKTESPIKLSPATPS 673
              PS + I     TP +  +  PI    +TP+
Sbjct: 199 TLTPSSRPILTRSSTPTLTPSSRPILTPSSTPT 231



 Score = 39.7 bits (91), Expect = 0.014
 Identities = 40/127 (31%), Positives = 52/127 (40%), Gaps = 9/127 (7%)

Query: 536 TTRPSTEEPVRRPQRPRSPPLPAVIRNAPSRP----PSLPTPRPASQPRKAPVISSTPKL 591
           T  PS+   +     P   P         SRP     S PT  P+S+P   P  SSTP L
Sbjct: 175 TLTPSSTPTLTPSSTPTLTPSSTPTLTPSSRPILTRSSTPTLTPSSRPILTP--SSTPTL 232

Query: 592 -PALAAREEASTSRLLQPPEAPR-KPANTLVKTASRPAPLVQQLSPSLLPNSKSPREVPS 649
            P+       S++  L P   P   P+NT   T S    L    +P+L P+S +P   PS
Sbjct: 233 TPSSRPILTRSSTPTLTPSSTPTLTPSNTPTLTPSNTPTLTPSNTPTLTPSS-TPTLTPS 291

Query: 650 PKVIKTP 656
                TP
Sbjct: 292 STPTLTP 298



 Score = 39.3 bits (90), Expect = 0.018
 Identities = 40/151 (26%), Positives = 57/151 (37%), Gaps = 5/151 (3%)

Query: 536 TTRPSTEEPVRRPQRPRSPPLPAVIRNAPSRPPSLPTPRPASQPRKAPVI--SSTPKL-P 592
           T  PS    +     P   P         SRP    +  P   P   P++  SSTP L P
Sbjct: 119 TLTPSNTPTLTPSSTPTLTPSSTPTLTPSSRPILTRSSTPTLTPSSRPILTRSSTPTLTP 178

Query: 593 ALAAREEASTSRLLQPPEAPR-KPANTLVKTASRPAPLVQQLSPSLLPNSKSPREVPSPK 651
           +       S++  L P   P   P++  + T S    L     P L P+S +P   PS +
Sbjct: 179 SSTPTLTPSSTPTLTPSSTPTLTPSSRPILTRSSTPTLTPSSRPILTPSS-TPTLTPSSR 237

Query: 652 VIKTPVVKKTESPIKLSPATPSRKRSVAVSD 682
            I T     T +P      TPS   ++  S+
Sbjct: 238 PILTRSSTPTLTPSSTPTLTPSNTPTLTPSN 268



 Score = 37.4 bits (85), Expect = 0.069
 Identities = 33/110 (30%), Positives = 44/110 (40%), Gaps = 12/110 (10%)

Query: 536 TTRPSTEEPVRRPQRPRSPPLPAVIRNAPSRPPSLPTPRPASQPRKAPVI--SSTPKL-P 592
           T  PS+   + R   P   P         SRP   P+  P   P   P++  SSTP L P
Sbjct: 199 TLTPSSRPILTRSSTPTLTP--------SSRPILTPSSTPTLTPSSRPILTRSSTPTLTP 250

Query: 593 ALAAREEASTSRLLQPPEAPR-KPANTLVKTASRPAPLVQQLSPSLLPNS 641
           +       S +  L P   P   P+NT   T S    L    +P+L P+S
Sbjct: 251 SSTPTLTPSNTPTLTPSNTPTLTPSNTPTLTPSSTPTLTPSSTPTLTPSS 300


>gi|153792074 proline rich 12 [Homo sapiens]
          Length = 2036

 Score = 48.1 bits (113), Expect = 4e-05
 Identities = 50/183 (27%), Positives = 67/183 (36%), Gaps = 23/183 (12%)

Query: 548  PQRPRSPPLPAVIRNAPSRPPSL-----PTPRPASQPRKAPVISSTPKLPALAAREEAST 602
            P  P  P LP+   N    PP L     PTP PA  P+  P     P  PAL +      
Sbjct: 1431 PGPPPLPGLPSANSNGTPEPPLLEEKPPPTPPPAPTPQPQPPPPPPPPQPALPSPPPLVA 1490

Query: 603  SRLLQPPEAPRKPANTLVKTASRPAPLVQQLSPSLLPNSKSPRE--VPSPKVIKTPVVKK 660
                 PP  P  P       +  P P      P+  P +  P E   PSP+  + P  + 
Sbjct: 1491 PTPSSPPPPPLPPPPPPAMPSPPPPP-----PPAAAPLAAPPEEPAAPSPEDPELPDTR- 1544

Query: 661  TESPIKLSPATPSRKRSVAVSDEEEVEEEAERRKERC--KRGRFVVKEEKKDSNELSDSA 718
                    P   ++K+  A    E  EE  E   E    +R  FV++ E   S +L+   
Sbjct: 1545 --------PLHLAKKQETAAVCGETDEEAGESGGEGIFRERDEFVIRAEDIPSLKLALQT 1596

Query: 719  GEE 721
            G E
Sbjct: 1597 GRE 1599



 Score = 41.2 bits (95), Expect = 0.005
 Identities = 27/85 (31%), Positives = 35/85 (41%), Gaps = 1/85 (1%)

Query: 532  PLEVTTRPSTEEPVRRPQRPRSPPLPAVIRNAPSRPPSLPTPRPASQPRKAPVISSTPKL 591
            PL     P T  P   PQ P+ PP P   + A   PP L  P P+S P         P +
Sbjct: 1451 PLLEEKPPPTPPPAPTPQ-PQPPPPPPPPQPALPSPPPLVAPTPSSPPPPPLPPPPPPAM 1509

Query: 592  PALAAREEASTSRLLQPPEAPRKPA 616
            P+       + + L  PPE P  P+
Sbjct: 1510 PSPPPPPPPAAAPLAAPPEEPAAPS 1534



 Score = 37.7 bits (86), Expect = 0.053
 Identities = 25/82 (30%), Positives = 31/82 (37%), Gaps = 6/82 (7%)

Query: 537  TRPSTEEPVRRPQRPRSPPLPAV------IRNAPSRPPSLPTPRPASQPRKAPVISSTPK 590
            T P    P  +P  P  PP PA+      +   PS PP  P P P      +P     P 
Sbjct: 1460 TPPPAPTPQPQPPPPPPPPQPALPSPPPLVAPTPSSPPPPPLPPPPPPAMPSPPPPPPPA 1519

Query: 591  LPALAAREEASTSRLLQPPEAP 612
               LAA  E   +   + PE P
Sbjct: 1520 AAPLAAPPEEPAAPSPEDPELP 1541


>gi|24431933 reticulon 4 isoform B [Homo sapiens]
          Length = 373

 Score = 47.8 bits (112), Expect = 5e-05
 Identities = 44/156 (28%), Positives = 71/156 (45%), Gaps = 15/156 (9%)

Query: 488 FRKDMKTQEEKQKQLTEKIRQQQEKLEALQKTTPIRSQADLKKLPLEVTTRPSTEEPVRR 547
           F ++ + +EE++++  E   +  E+LE L++    +  A L   P  V T P+   P+  
Sbjct: 27  FVREPEDEEEEEEEEEEDEDEDLEELEVLER----KPAAGLSAAP--VPTAPAAGAPLMD 80

Query: 548 ------PQRPRSPPLPAVIRNAPSRPPSL-PTPRPASQPRKAPVISSTPKLPALAAREEA 600
                 P  PR P LPA    AP R PS  P+P  ++ P  +P +S+    P+    ++ 
Sbjct: 81  FGNDFVPPAPRGP-LPAAPPVAPERQPSWDPSPVSSTVPAPSP-LSAAAVSPSKLPEDDE 138

Query: 601 STSRLLQPPEAPRKPANTLVKTASRPAPLVQQLSPS 636
             +R   PP A   P    V T   PAP     +P+
Sbjct: 139 PPARPPPPPPASVSPQAEPVWTPPAPAPAAPPSTPA 174


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.314    0.131    0.377 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 39,485,844
Number of Sequences: 37866
Number of extensions: 2091468
Number of successful extensions: 21105
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 180
Number of HSP's successfully gapped in prelim test: 1209
Number of HSP's that attempted gapping in prelim test: 13457
Number of HSP's gapped (non-prelim): 6427
length of query: 970
length of database: 18,247,518
effective HSP length: 112
effective length of query: 858
effective length of database: 14,006,526
effective search space: 12017599308
effective search space used: 12017599308
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 67 (30.4 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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