BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|7662316 HIV-1 Vpr binding protein [Homo sapiens] (1507 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|7662316 HIV-1 Vpr binding protein [Homo sapiens] 3024 0.0 gi|55956788 nucleolin [Homo sapiens] 68 8e-11 gi|5454088 acidic (leucine-rich) nuclear phosphoprotein 32 famil... 62 3e-09 gi|60498973 myelin transcription factor 1-like [Homo sapiens] 62 3e-09 gi|210032580 SET domain containing 1B [Homo sapiens] 62 3e-09 gi|21735415 centromere protein B [Homo sapiens] 61 7e-09 gi|115529449 upstream binding transcription factor, RNA polymera... 61 7e-09 gi|115529451 upstream binding transcription factor, RNA polymera... 61 7e-09 gi|7657671 upstream binding transcription factor, RNA polymerase... 61 7e-09 gi|239756368 PREDICTED: similar to acidic (leucine-rich) nuclear... 61 9e-09 gi|239750893 PREDICTED: similar to acidic (leucine-rich) nuclear... 61 9e-09 gi|214010181 amyloid beta (A4) precursor-like protein 2 isoform ... 60 2e-08 gi|4502147 amyloid beta (A4) precursor-like protein 2 isoform 1 ... 60 2e-08 gi|214010183 amyloid beta (A4) precursor-like protein 2 isoform ... 60 2e-08 gi|61676188 HECT, UBA and WWE domain containing 1 [Homo sapiens] 59 5e-08 gi|155030232 proline, glutamic acid and leucine rich protein 1 [... 58 8e-08 gi|4503257 death-domain associated protein isoform a [Homo sapiens] 55 4e-07 gi|215422388 death-domain associated protein isoform a [Homo sap... 55 4e-07 gi|215422366 death-domain associated protein isoform b [Homo sap... 55 4e-07 gi|17975763 myelin transcription factor 1 [Homo sapiens] 55 4e-07 gi|195546902 suppressor of Ty 5 homolog isoform b [Homo sapiens] 55 7e-07 gi|114155142 nuclear pore complex-associated protein TPR [Homo s... 54 9e-07 gi|16445033 ACRC protein [Homo sapiens] 54 1e-06 gi|42740903 MTERF domain containing 2 [Homo sapiens] 53 2e-06 gi|86262149 zinc finger and BTB domain containing 7C [Homo sapiens] 53 2e-06 gi|42476169 Paf1, RNA polymerase II associated factor, homolog [... 53 2e-06 gi|195546900 suppressor of Ty 5 homolog isoform a [Homo sapiens] 53 3e-06 gi|161169023 suppressor of Ty 5 homolog isoform a [Homo sapiens] 53 3e-06 gi|20149524 suppressor of Ty 5 homolog isoform a [Homo sapiens] 53 3e-06 gi|210147569 acidic (leucine-rich) nuclear phosphoprotein 32 fam... 53 3e-06 >gi|7662316 HIV-1 Vpr binding protein [Homo sapiens] Length = 1507 Score = 3024 bits (7840), Expect = 0.0 Identities = 1507/1507 (100%), Positives = 1507/1507 (100%) Query: 1 MTTVVVHVDSKAELTTLLEQWEKEHGSGQDMVPILTRMSQLIEKETEEYRKGDPDPFDDR 60 MTTVVVHVDSKAELTTLLEQWEKEHGSGQDMVPILTRMSQLIEKETEEYRKGDPDPFDDR Sbjct: 1 MTTVVVHVDSKAELTTLLEQWEKEHGSGQDMVPILTRMSQLIEKETEEYRKGDPDPFDDR 60 Query: 61 HPGRADPECMLGHLLRILFKNDDFMNALVNAYVMTSREPPLNTAACRLLLDIMPGLETAV 120 HPGRADPECMLGHLLRILFKNDDFMNALVNAYVMTSREPPLNTAACRLLLDIMPGLETAV Sbjct: 61 HPGRADPECMLGHLLRILFKNDDFMNALVNAYVMTSREPPLNTAACRLLLDIMPGLETAV 120 Query: 121 VFQEKEGIVENLFKWAREADQPLRTYSTGLLGGAMENQDIAANYRDENSQLVAIVLRRLR 180 VFQEKEGIVENLFKWAREADQPLRTYSTGLLGGAMENQDIAANYRDENSQLVAIVLRRLR Sbjct: 121 VFQEKEGIVENLFKWAREADQPLRTYSTGLLGGAMENQDIAANYRDENSQLVAIVLRRLR 180 Query: 181 ELQLQEVALRQENKRPSPRKLSSEPLLPLDEEAVDMDYGDMAVDVVDGDQEEASGDMEIS 240 ELQLQEVALRQENKRPSPRKLSSEPLLPLDEEAVDMDYGDMAVDVVDGDQEEASGDMEIS Sbjct: 181 ELQLQEVALRQENKRPSPRKLSSEPLLPLDEEAVDMDYGDMAVDVVDGDQEEASGDMEIS 240 Query: 241 FHLDSGHKTSSRVNSTTKPEDGGLKKNKSAKQGDRENFRKAKQKLGFSSSDPDRMFVELS 300 FHLDSGHKTSSRVNSTTKPEDGGLKKNKSAKQGDRENFRKAKQKLGFSSSDPDRMFVELS Sbjct: 241 FHLDSGHKTSSRVNSTTKPEDGGLKKNKSAKQGDRENFRKAKQKLGFSSSDPDRMFVELS 300 Query: 301 NSSWSEMSPWVIGTNYTLYPMTPAIEQRLILQYLTPLGEYQELLPIFMQLGSRELMMFYI 360 NSSWSEMSPWVIGTNYTLYPMTPAIEQRLILQYLTPLGEYQELLPIFMQLGSRELMMFYI Sbjct: 301 NSSWSEMSPWVIGTNYTLYPMTPAIEQRLILQYLTPLGEYQELLPIFMQLGSRELMMFYI 360 Query: 361 DLKQTNDVLLTFEALKHLASLLLHNKFATEFVAHGGVQKLLEIPRPSMAATGVSMCLYYL 420 DLKQTNDVLLTFEALKHLASLLLHNKFATEFVAHGGVQKLLEIPRPSMAATGVSMCLYYL Sbjct: 361 DLKQTNDVLLTFEALKHLASLLLHNKFATEFVAHGGVQKLLEIPRPSMAATGVSMCLYYL 420 Query: 421 SYNQDAMERVCMHPHNVLSDVVNYTLWLMECSHASGCCHATMFFSICFSFRAVLELFDRY 480 SYNQDAMERVCMHPHNVLSDVVNYTLWLMECSHASGCCHATMFFSICFSFRAVLELFDRY Sbjct: 421 SYNQDAMERVCMHPHNVLSDVVNYTLWLMECSHASGCCHATMFFSICFSFRAVLELFDRY 480 Query: 481 DGLRRLVNLISTLEILNLEDQGALLSDDEIFASRQTGKHTCMALRKYFEAHLAIKLEQVK 540 DGLRRLVNLISTLEILNLEDQGALLSDDEIFASRQTGKHTCMALRKYFEAHLAIKLEQVK Sbjct: 481 DGLRRLVNLISTLEILNLEDQGALLSDDEIFASRQTGKHTCMALRKYFEAHLAIKLEQVK 540 Query: 541 QSLQRTEGGILVHPQPPYKACSYTHEQIVEMMEFLIEYGPAQLYWEPAEVFLKLSCVQLL 600 QSLQRTEGGILVHPQPPYKACSYTHEQIVEMMEFLIEYGPAQLYWEPAEVFLKLSCVQLL Sbjct: 541 QSLQRTEGGILVHPQPPYKACSYTHEQIVEMMEFLIEYGPAQLYWEPAEVFLKLSCVQLL 600 Query: 601 LQLISIACNWKTYYARNDTVRFALDVLAILTVVPKIQLQLAESVDVLDEAGSTVSTVGIS 660 LQLISIACNWKTYYARNDTVRFALDVLAILTVVPKIQLQLAESVDVLDEAGSTVSTVGIS Sbjct: 601 LQLISIACNWKTYYARNDTVRFALDVLAILTVVPKIQLQLAESVDVLDEAGSTVSTVGIS 660 Query: 661 IILGVAEGEFFIHDAEIQKSALQIIINCVCGPDNRISSIGKFISGTPRRKLPQNPKSSEH 720 IILGVAEGEFFIHDAEIQKSALQIIINCVCGPDNRISSIGKFISGTPRRKLPQNPKSSEH Sbjct: 661 IILGVAEGEFFIHDAEIQKSALQIIINCVCGPDNRISSIGKFISGTPRRKLPQNPKSSEH 720 Query: 721 TLAKMWNVVQSNNGIKVLLSLLSIKMPITDADQIRALACKALVGLSRSSTVRQIISKLPL 780 TLAKMWNVVQSNNGIKVLLSLLSIKMPITDADQIRALACKALVGLSRSSTVRQIISKLPL Sbjct: 721 TLAKMWNVVQSNNGIKVLLSLLSIKMPITDADQIRALACKALVGLSRSSTVRQIISKLPL 780 Query: 781 FSSCQIQQLMKEPVLQDKRSDHVKFCKYAAELIERVSGKPLLIGTDVSLARLQKADVVAQ 840 FSSCQIQQLMKEPVLQDKRSDHVKFCKYAAELIERVSGKPLLIGTDVSLARLQKADVVAQ Sbjct: 781 FSSCQIQQLMKEPVLQDKRSDHVKFCKYAAELIERVSGKPLLIGTDVSLARLQKADVVAQ 840 Query: 841 SRISFPEKELLLLIRNHLISKGLGETATVLTKEADLPMTAASHSSAFTPVTAAASPVSLP 900 SRISFPEKELLLLIRNHLISKGLGETATVLTKEADLPMTAASHSSAFTPVTAAASPVSLP Sbjct: 841 SRISFPEKELLLLIRNHLISKGLGETATVLTKEADLPMTAASHSSAFTPVTAAASPVSLP 900 Query: 901 RTPRIANGIATRLGSHAAVGASAPSAPTAHPQPRPPQGPLALPGPSYAGNSPLIGRISFI 960 RTPRIANGIATRLGSHAAVGASAPSAPTAHPQPRPPQGPLALPGPSYAGNSPLIGRISFI Sbjct: 901 RTPRIANGIATRLGSHAAVGASAPSAPTAHPQPRPPQGPLALPGPSYAGNSPLIGRISFI 960 Query: 961 RERPSPCNGRKIRVLRQKSDHGAYSQSPAIKKQLDRHLPSPPTLDSIITEYLREQHARCK 1020 RERPSPCNGRKIRVLRQKSDHGAYSQSPAIKKQLDRHLPSPPTLDSIITEYLREQHARCK Sbjct: 961 RERPSPCNGRKIRVLRQKSDHGAYSQSPAIKKQLDRHLPSPPTLDSIITEYLREQHARCK 1020 Query: 1021 NPVATCPPFSLFTPHQCPEPKQRRQAPINFTSRLNRRASFPKYGGVDGGCFDRHLIFSRF 1080 NPVATCPPFSLFTPHQCPEPKQRRQAPINFTSRLNRRASFPKYGGVDGGCFDRHLIFSRF Sbjct: 1021 NPVATCPPFSLFTPHQCPEPKQRRQAPINFTSRLNRRASFPKYGGVDGGCFDRHLIFSRF 1080 Query: 1081 RPISVFREANEDESGFTCCAFSARERFLMLGTCTGQLKLYNVFSGQEEASYNCHNSAITH 1140 RPISVFREANEDESGFTCCAFSARERFLMLGTCTGQLKLYNVFSGQEEASYNCHNSAITH Sbjct: 1081 RPISVFREANEDESGFTCCAFSARERFLMLGTCTGQLKLYNVFSGQEEASYNCHNSAITH 1140 Query: 1141 LEPSRDGSLLLTSATWSQPLSALWGMKSVFDMKHSFTEDHYVEFSKHSQDRVIGTKGDIA 1200 LEPSRDGSLLLTSATWSQPLSALWGMKSVFDMKHSFTEDHYVEFSKHSQDRVIGTKGDIA Sbjct: 1141 LEPSRDGSLLLTSATWSQPLSALWGMKSVFDMKHSFTEDHYVEFSKHSQDRVIGTKGDIA 1200 Query: 1201 HIYDIQTGNKLLTLFNPDLANNYKRNCATFNPTDDLVLNDGVLWDVRSAQAIHKFDKFNM 1260 HIYDIQTGNKLLTLFNPDLANNYKRNCATFNPTDDLVLNDGVLWDVRSAQAIHKFDKFNM Sbjct: 1201 HIYDIQTGNKLLTLFNPDLANNYKRNCATFNPTDDLVLNDGVLWDVRSAQAIHKFDKFNM 1260 Query: 1261 NISGVFHPNGLEVIINTEIWDLRTFHLLHTVPALDQCRVVFNHTGTVMYGAMLQADDEDD 1320 NISGVFHPNGLEVIINTEIWDLRTFHLLHTVPALDQCRVVFNHTGTVMYGAMLQADDEDD Sbjct: 1261 NISGVFHPNGLEVIINTEIWDLRTFHLLHTVPALDQCRVVFNHTGTVMYGAMLQADDEDD 1320 Query: 1321 LMEERMKSPFGSSFRTFNATDYKPIATIDVKRNIFDLCTDTKDCYLAVIENQGSMDALNM 1380 LMEERMKSPFGSSFRTFNATDYKPIATIDVKRNIFDLCTDTKDCYLAVIENQGSMDALNM Sbjct: 1321 LMEERMKSPFGSSFRTFNATDYKPIATIDVKRNIFDLCTDTKDCYLAVIENQGSMDALNM 1380 Query: 1381 DTVCRLYEVGRQRLAEDEDEEEDQEEEEQEEEDDDEDDDDTDDLDELDTDQLLEAELEED 1440 DTVCRLYEVGRQRLAEDEDEEEDQEEEEQEEEDDDEDDDDTDDLDELDTDQLLEAELEED Sbjct: 1381 DTVCRLYEVGRQRLAEDEDEEEDQEEEEQEEEDDDEDDDDTDDLDELDTDQLLEAELEED 1440 Query: 1441 DNNENAGEDGDNDFSPSDEELANLLEEGEDGEDEDSDADEEVELILGDTDSSDNSDLEDD 1500 DNNENAGEDGDNDFSPSDEELANLLEEGEDGEDEDSDADEEVELILGDTDSSDNSDLEDD Sbjct: 1441 DNNENAGEDGDNDFSPSDEELANLLEEGEDGEDEDSDADEEVELILGDTDSSDNSDLEDD 1500 Query: 1501 IILSLNE 1507 IILSLNE Sbjct: 1501 IILSLNE 1507 >gi|55956788 nucleolin [Homo sapiens] Length = 710 Score = 67.8 bits (164), Expect = 8e-11 Identities = 42/136 (30%), Positives = 64/136 (47%), Gaps = 30/136 (22%) Query: 1390 GRQRLAEDEDEEEDQEEEEQEEEDDDEDDDDTDDLDELDTDQLLEAELEEDDNNENAGED 1449 G+ ED DEEED + EE EE+D+DED+D+ D+++ A ED+++E+ +D Sbjct: 137 GKNAKKEDSDEEEDDDSEEDEEDDEDEDEDE-DEIEPAAMKAAAAAPASEDEDDEDDEDD 195 Query: 1450 GDNDFSPSDEELANLLE-------------------------EGEDGEDEDSDADEEVEL 1484 D+D D+ +E E ED EDED D DE+ E Sbjct: 196 EDDDDDEEDDSEEEAMETTPAKGKKAAKVVPVKAKNVAEDEDEEEDDEDEDDDDDEDDE- 254 Query: 1485 ILGDTDSSDNSDLEDD 1500 D D D+ + E++ Sbjct: 255 ---DDDDEDDEEEEEE 267 Score = 56.6 bits (135), Expect = 2e-07 Identities = 36/118 (30%), Positives = 57/118 (48%), Gaps = 37/118 (31%) Query: 1396 EDEDEEEDQEEEE------------QEEEDDDEDDDDTDDLDELDTDQLLEA-------- 1435 +DEDE+ED++E E E+EDD++D+DD DD D+ + D EA Sbjct: 159 DDEDEDEDEDEIEPAAMKAAAAAPASEDEDDEDDEDDEDDDDDEEDDSEEEAMETTPAKG 218 Query: 1436 ------------ELEEDDNNENAGEDGDNDFSPSDEELANLLEEGEDGEDEDSDADEE 1481 + ED++ E ED D+D DE+ ++ ED E+E+ + +EE Sbjct: 219 KKAAKVVPVKAKNVAEDEDEEEDDEDEDDDDDEDDED-----DDDEDDEEEEEEEEEE 271 Score = 56.2 bits (134), Expect = 2e-07 Identities = 28/64 (43%), Positives = 41/64 (64%), Gaps = 7/64 (10%) Query: 1385 RLYEVGRQRLAEDEDEEEDQEEEEQEEEDDDEDDDDTDDLDELDTDQLLEAELEEDDNNE 1444 ++ V + +AEDEDEEED E+E+ ++++DDEDDDD DD +E E E EE+ E Sbjct: 223 KVVPVKAKNVAEDEDEEEDDEDEDDDDDEDDEDDDDEDDEEE-------EEEEEEEPVKE 275 Query: 1445 NAGE 1448 G+ Sbjct: 276 APGK 279 Score = 42.0 bits (97), Expect = 0.004 Identities = 24/80 (30%), Positives = 37/80 (46%), Gaps = 27/80 (33%) Query: 1396 EDEDEEEDQEEEE---------------------------QEEEDDDEDDDDTDDLDELD 1428 ED+D++E+ + EE ++EE+DDED+DD DD D+ D Sbjct: 196 EDDDDDEEDDSEEEAMETTPAKGKKAAKVVPVKAKNVAEDEDEEEDDEDEDDDDDEDDED 255 Query: 1429 TDQLLEAELEEDDNNENAGE 1448 D + E EE++ E E Sbjct: 256 DDDEDDEEEEEEEEEEPVKE 275 Score = 42.0 bits (97), Expect = 0.004 Identities = 25/84 (29%), Positives = 40/84 (47%), Gaps = 26/84 (30%) Query: 1396 EDEDEEEDQEEEEQEE--------------------EDDDEDDDDTDDLDELDTDQLLEA 1435 +D+DEE+D EEE E ED+DE++DD D+ D+ D D Sbjct: 198 DDDDEEDDSEEEAMETTPAKGKKAAKVVPVKAKNVAEDEDEEEDDEDEDDDDDEDD---- 253 Query: 1436 ELEEDDNNENAGEDGDNDFSPSDE 1459 E+DD+ ++ E+ + + P E Sbjct: 254 --EDDDDEDDEEEEEEEEEEPVKE 275 >gi|5454088 acidic (leucine-rich) nuclear phosphoprotein 32 family, member B [Homo sapiens] Length = 251 Score = 62.4 bits (150), Expect = 3e-09 Identities = 39/90 (43%), Positives = 52/90 (57%), Gaps = 13/90 (14%) Query: 1395 AEDEDEEEDQ-EEEEQEEEDDDEDDDDTDDLDELDTDQLLEAELEEDDNNENAGEDGDND 1453 A D D E D +EEE++EE +DE+D+D +D +E + D EEDD +E+ D D+D Sbjct: 155 APDSDAEVDGVDEEEEDEEGEDEEDEDDEDGEEEEFD-------EEDDEDEDVEGDEDDD 207 Query: 1454 FSPSDEELANLLEEGEDGEDEDSDADEEVE 1483 +EE E G D EDED D DEE E Sbjct: 208 EVSEEEE-----EFGLDEEDEDEDEDEEEE 232 Score = 55.5 bits (132), Expect = 4e-07 Identities = 34/88 (38%), Positives = 49/88 (55%), Gaps = 11/88 (12%) Query: 1396 EDEDEEEDQEEEEQEEEDDDEDDDDTDDLDELDTDQLLEAELEEDDNNENAGEDGDNDFS 1455 E EDEE++ +E+ +EEE D+EDD+D D + D D++ E E E + E+ ED D Sbjct: 173 EGEDEEDEDDEDGEEEEFDEEDDEDEDVEGDEDDDEVSEEEEEFGLDEEDEDEDED---- 228 Query: 1456 PSDEELANLLEEGEDGEDEDSDADEEVE 1483 +EE EEG GE + D+E E Sbjct: 229 --EEE-----EEGGKGEKRKRETDDEGE 249 Score = 49.3 bits (116), Expect = 3e-05 Identities = 28/78 (35%), Positives = 48/78 (61%), Gaps = 8/78 (10%) Query: 1396 EDEDEEEDQEEE--EQEEEDDD-EDDDDTDDLDELDTDQLLEAELEEDDNNENAGEDGDN 1452 EDED+E+ +EEE E+++ED+D E D+D D++ E + + L+ E E++D +E E G Sbjct: 178 EDEDDEDGEEEEFDEEDDEDEDVEGDEDDDEVSEEEEEFGLDEEDEDEDEDEEEEEGGKG 237 Query: 1453 DFSPSDEELANLLEEGED 1470 + + + +EGED Sbjct: 238 EKRKRETD-----DEGED 250 Score = 38.5 bits (88), Expect = 0.050 Identities = 26/71 (36%), Positives = 33/71 (46%), Gaps = 2/71 (2%) Query: 1437 LEEDDNNENAGEDGDNDFSPSDEELANLLEEGEDGEDEDSDADEEVELILGDTDSSDNSD 1496 L+ D + D D + DEE + EEGED EDED + EE E D + D Sbjct: 145 LDGYDREDQEAPDSDAEVDGVDEEEED--EEGEDEEDEDDEDGEEEEFDEEDDEDEDVEG 202 Query: 1497 LEDDIILSLNE 1507 EDD +S E Sbjct: 203 DEDDDEVSEEE 213 Score = 34.7 bits (78), Expect = 0.72 Identities = 17/37 (45%), Positives = 24/37 (64%), Gaps = 4/37 (10%) Query: 1388 EVGRQRLAEDEDEEEDQEE----EEQEEEDDDEDDDD 1420 E G EDEDE+E++EE E+++ E DDE +DD Sbjct: 215 EFGLDEEDEDEDEDEEEEEGGKGEKRKRETDDEGEDD 251 >gi|60498973 myelin transcription factor 1-like [Homo sapiens] Length = 1184 Score = 62.4 bits (150), Expect = 3e-09 Identities = 40/121 (33%), Positives = 69/121 (57%), Gaps = 21/121 (17%) Query: 1396 EDEDEEEDQEEEEQEEEDDDEDDDDTDDLDELDTDQLLEAELEEDDNNEN---------- 1445 ++EDEE D+EEEE+ EE+D++DD+D +D+++ + ++ E E EE++ NE+ Sbjct: 121 DEEDEEGDREEEEEIEEEDEDDDEDGEDVEDEEEEEEEEEEEEEEEENEDHQMNCHNTRI 180 Query: 1446 ----AGEDGDNDFSPSDEELA--NLLEEGEDGEDEDSDADEEVELILGDTDSSDNSDLED 1499 +D +ND + +EL +LL G+ ED A E E+ +S+ ++ LED Sbjct: 181 MQDTEKDDNNNDEYDNYDELVAKSLLNLGKIAEDAAYRARTESEM-----NSNTSNSLED 235 Query: 1500 D 1500 D Sbjct: 236 D 236 Score = 62.0 bits (149), Expect = 4e-09 Identities = 39/105 (37%), Positives = 63/105 (60%), Gaps = 6/105 (5%) Query: 1396 EDEDEEEDQEEEEQEEEDDDEDDDDTDDLDELDTDQLLEAELEEDDNNENAGEDGDNDFS 1455 ED DE+E+ E EE E++D+ D+D +D +E D ++ E E+EE+D +++ EDG+ D Sbjct: 97 EDMDEKEEDEGEEYSEDNDEPGDEDEED-EEGDREE--EEEIEEEDEDDD--EDGE-DVE 150 Query: 1456 PSDEELANLLEEGEDGEDEDSDADEEVELILGDTDSSDNSDLEDD 1500 +EE EE E+ E+ED + I+ DT+ DN++ E D Sbjct: 151 DEEEEEEEEEEEEEEEENEDHQMNCHNTRIMQDTEKDDNNNDEYD 195 Score = 47.8 bits (112), Expect = 8e-05 Identities = 29/118 (24%), Positives = 58/118 (49%), Gaps = 11/118 (9%) Query: 1389 VGRQRLAEDEDEEEDQEEE-------EQEEEDDDEDDDDTDDLDELDTDQLLEAELEEDD 1441 + ++R +D+ +E + + D+ +D D T+D+DE + D E E +D Sbjct: 57 LAKKRKTQDKQPQEPAPKRKPFAVKADSSSVDECDDSDGTEDMDEKEED---EGEEYSED 113 Query: 1442 NNENAGEDGDNDFSPSDEELANLLEEGEDGEDEDSDADEEVELILGDTDSSDNSDLED 1499 N+E ED +++ +EE + EE ED +++ D ++E E + + + + ED Sbjct: 114 NDEPGDEDEEDEEGDREEE-EEIEEEDEDDDEDGEDVEDEEEEEEEEEEEEEEEENED 170 Score = 44.3 bits (103), Expect = 0.001 Identities = 27/108 (25%), Positives = 51/108 (47%), Gaps = 1/108 (0%) Query: 1394 LAEDEDEEEDQEEEEQEEEDDDEDDDDTDDLDEL-DTDQLLEAELEEDDNNENAGEDGDN 1452 LA+ ++ Q +E + D+ +DE D+D + + +E+D E ED D Sbjct: 57 LAKKRKTQDKQPQEPAPKRKPFAVKADSSSVDECDDSDGTEDMDEKEEDEGEEYSEDNDE 116 Query: 1453 DFSPSDEELANLLEEGEDGEDEDSDADEEVELILGDTDSSDNSDLEDD 1500 +E+ EE E+ E+ED D DE+ E + + + + + E++ Sbjct: 117 PGDEDEEDEEGDREEEEEIEEEDEDDDEDGEDVEDEEEEEEEEEEEEE 164 Score = 36.6 bits (83), Expect = 0.19 Identities = 30/115 (26%), Positives = 49/115 (42%), Gaps = 25/115 (21%) Query: 1396 EDEDEEEDQEEE--------EQEEEDDDEDDDDTDDLDELDTDQLLEAELEEDDNNENAG 1447 E+E+EEE+++ + Q+ E DD ++D+ D+ DEL LL N Sbjct: 161 EEEEEEENEDHQMNCHNTRIMQDTEKDDNNNDEYDNYDELVAKSLL--------NLGKIA 212 Query: 1448 EDGDNDFSPSDEELANLLEEGEDGEDEDSDADEEVELILGDTDSSDNSDLEDDII 1502 ED E +N ED D++ + + EL L DL+ D++ Sbjct: 213 EDAAYRARTESEMNSNTSNSLEDDSDKNENLGRKSELSL---------DLDSDVV 258 >gi|210032580 SET domain containing 1B [Homo sapiens] Length = 1923 Score = 62.4 bits (150), Expect = 3e-09 Identities = 33/112 (29%), Positives = 58/112 (51%), Gaps = 10/112 (8%) Query: 1391 RQRLAEDEDEEEDQEEEEQEEEDDDEDDDDTDDLDELDTDQLLEAELEEDDNNENAGEDG 1450 ++ L+E+++ E++EE E+EEE++D+DDDD+DD D E E DD + E Sbjct: 1038 KESLSEEQESTEEEEEAEEEEEEEDDDDDDSDDRD----------ESENDDEDTALSEAS 1087 Query: 1451 DNDFSPSDEELANLLEEGEDGEDEDSDADEEVELILGDTDSSDNSDLEDDII 1502 + D SDEE + + S++ E E S +S+ E++++ Sbjct: 1088 EKDEGDSDEEETVSIVTSKAEATSSSESSESSEFESSSESSPSSSEDEEEVV 1139 Score = 52.4 bits (124), Expect = 3e-06 Identities = 32/129 (24%), Positives = 64/129 (49%), Gaps = 17/129 (13%) Query: 1389 VGRQRLAEDEDEEEDQEEEEQEEEDDDEDDDDTDDLDELDTDQLLEAELEEDDNNE---- 1444 + ++ + +E+EE ++EEEE++++DDD DD D + D+ DT +E +E D++E Sbjct: 1041 LSEEQESTEEEEEAEEEEEEEDDDDDDSDDRDESENDDEDTALSEASEKDEGDSDEEETV 1100 Query: 1445 -----------NAGEDGDNDFSPSDEELANLLEEGEDGEDEDSDADEEVELILGDTD--S 1491 ++ ++F S E + E+ E+ + + +EE E ++ + S Sbjct: 1101 SIVTSKAEATSSSESSESSEFESSSESSPSSSEDEEEVVAREEEEEEEEEEMVAEESMAS 1160 Query: 1492 SDNSDLEDD 1500 + D E D Sbjct: 1161 AGPEDFEQD 1169 Score = 41.2 bits (95), Expect = 0.008 Identities = 28/140 (20%), Positives = 60/140 (42%), Gaps = 34/140 (24%) Query: 1390 GRQRLAEDEDEEEDQEEEEQEEEDDD---------------------------------E 1416 G Q+ ++++EE + E D D E Sbjct: 976 GDQKRLRPSTSVDEEDEESERERDRDMADTPCELAKRDPKGVGVRRRPARPLELDSGGEE 1035 Query: 1417 DDDDTDDLDELDTDQLLEAELEEDDNNENAGEDGDNDFSPSDEELANLLEEGEDGEDEDS 1476 D+ ++ ++ T++ EAE EE++ +++ + D D S +D+E L E + ++ DS Sbjct: 1036 DEKESLSEEQESTEEEEEAEEEEEEEDDDDDDSDDRDESENDDE-DTALSEASEKDEGDS 1094 Query: 1477 DADEEVELILGDTDSSDNSD 1496 D +E V ++ +++ +S+ Sbjct: 1095 DEEETVSIVTSKAEATSSSE 1114 Score = 35.8 bits (81), Expect = 0.32 Identities = 25/115 (21%), Positives = 54/115 (46%), Gaps = 12/115 (10%) Query: 1403 DQEEEEQEEEDDDEDDDDTDDLDELDTDQL-------LEAELE---EDDNNENAGEDGDN 1452 D+E+EE E E D + D +L + D + EL+ E+D E+ E+ ++ Sbjct: 988 DEEDEESERERDRDMADTPCELAKRDPKGVGVRRRPARPLELDSGGEEDEKESLSEEQES 1047 Query: 1453 --DFSPSDEELANLLEEGEDGEDEDSDADEEVELILGDTDSSDNSDLEDDIILSL 1505 + ++EE ++ +D +D D +++ + L + D D +++ +S+ Sbjct: 1048 TEEEEEAEEEEEEEDDDDDDSDDRDESENDDEDTALSEASEKDEGDSDEEETVSI 1102 >gi|21735415 centromere protein B [Homo sapiens] Length = 599 Score = 61.2 bits (147), Expect = 7e-09 Identities = 39/142 (27%), Positives = 69/142 (48%), Gaps = 21/142 (14%) Query: 1379 NMDTVCRLYEVGRQRLAEDEDEEEDQEEEEQEEEDDDEDDDDTDDLDELDTDQLLEAELE 1438 N L G + E+E+EEE++ E E+EEE+ +E++++ + +EL ++ +E E + Sbjct: 394 NATITTSLKSEGEEEEEEEEEEEEEEGEGEEEEEEGEEEEEEGGEGEELGEEEEVEEEGD 453 Query: 1439 ED-DNNENAGEDGDNDFSPSDEELANLLEEG--------------------EDGEDEDSD 1477 D D E E+ ++ +++ ++E G E GED DSD Sbjct: 454 VDSDEEEEEDEESSSEGLEAEDWAQGVVEAGGSFGAYGAQEEAQCPTLHFLEGGEDSDSD 513 Query: 1478 ADEEVELILGDTDSSDNSDLED 1499 ++EE + D D D+ D ED Sbjct: 514 SEEEDDEEEDDEDEDDDDDEED 535 Score = 49.3 bits (116), Expect = 3e-05 Identities = 38/123 (30%), Positives = 57/123 (46%), Gaps = 32/123 (26%) Query: 1388 EVGRQRLAEDEDEEEDQE--------EEEQEEEDDDEDDDDTDDLDELDTDQLLEAE--- 1436 E G E+E EEE++E EEE+ EE+ D D D+ ++ DE + + LEAE Sbjct: 418 EEGEGEEEEEEGEEEEEEGGEGEELGEEEEVEEEGDVDSDEEEEEDEESSSEGLEAEDWA 477 Query: 1437 --LEEDDNNENA-----------------GEDGDNDFSPSDEELANLLEEGEDGEDEDSD 1477 + E + A GED D+D D+E + +E ED +D++ D Sbjct: 478 QGVVEAGGSFGAYGAQEEAQCPTLHFLEGGEDSDSDSEEEDDEEED--DEDEDDDDDEED 535 Query: 1478 ADE 1480 DE Sbjct: 536 GDE 538 Score = 45.8 bits (107), Expect = 3e-04 Identities = 22/76 (28%), Positives = 40/76 (52%) Query: 1360 DTKDCYLAVIENQGSMDALNMDTVCRLYEVGRQRLAEDEDEEEDQEEEEQEEEDDDEDDD 1419 + +D V+E GS A + + ED D + ++E++E+E+++D++DDD Sbjct: 472 EAEDWAQGVVEAGGSFGAYGAQEEAQCPTLHFLEGGEDSDSDSEEEDDEEEDDEDEDDDD 531 Query: 1420 DTDDLDELDTDQLLEA 1435 D +D DE+ EA Sbjct: 532 DEEDGDEVPVPSFGEA 547 Score = 33.9 bits (76), Expect = 1.2 Identities = 22/60 (36%), Positives = 27/60 (45%), Gaps = 24/60 (40%) Query: 1398 EDEEEDQEEEEQEEEDDDEDDDDTDDLDELDTDQLLEAELEEDDNNENAGEDGDNDFSPS 1457 ED + D EEE+ EEEDD+++DDD D E EDGD PS Sbjct: 508 EDSDSDSEEEDDEEEDDEDEDDDDD---------------------E---EDGDEVPVPS 543 >gi|115529449 upstream binding transcription factor, RNA polymerase I isoform b [Homo sapiens] Length = 727 Score = 61.2 bits (147), Expect = 7e-09 Identities = 32/101 (31%), Positives = 56/101 (55%), Gaps = 13/101 (12%) Query: 1395 AEDEDEEEDQEEEEQEEEDDDEDDDDTDDLDELDTDQLLEAELEEDDNNENAGEDGDNDF 1454 +E++DEE++ +E+E EEE+DDE+ D ++D + ++ E E E+ D NE ED D+D Sbjct: 640 SEEDDEEDEDDEDEDEEEEDDENGDSSEDGGD-SSESSSEDESEDGDENEEDDEDEDDD- 697 Query: 1455 SPSDEELANLLEEGEDGEDEDSDADEEVELILGDTDSSDNS 1495 E+ ++ ED +S+ GD+ SD++ Sbjct: 698 -----------EDDDEDEDNESEGSSSSSSSSGDSSDSDSN 727 Score = 57.8 bits (138), Expect = 8e-08 Identities = 36/97 (37%), Positives = 51/97 (52%), Gaps = 12/97 (12%) Query: 1405 EEEEQEEEDDDEDDDDTDDLDELDTDQLLEAELEEDDNNENAGED-GDNDFSPSDEELAN 1463 + + + EEDD+ED+DD D E E EEDD N ++ ED GD+ S S++E + Sbjct: 635 QSKSESEEDDEEDEDDED-----------EDEEEEDDENGDSSEDGGDSSESSSEDESED 683 Query: 1464 LLEEGEDGEDEDSDADEEVELILGDTDSSDNSDLEDD 1500 E ED EDED D D++ + SS +S D Sbjct: 684 GDENEEDDEDEDDDEDDDEDEDNESEGSSSSSSSSGD 720 >gi|115529451 upstream binding transcription factor, RNA polymerase I isoform b [Homo sapiens] Length = 727 Score = 61.2 bits (147), Expect = 7e-09 Identities = 32/101 (31%), Positives = 56/101 (55%), Gaps = 13/101 (12%) Query: 1395 AEDEDEEEDQEEEEQEEEDDDEDDDDTDDLDELDTDQLLEAELEEDDNNENAGEDGDNDF 1454 +E++DEE++ +E+E EEE+DDE+ D ++D + ++ E E E+ D NE ED D+D Sbjct: 640 SEEDDEEDEDDEDEDEEEEDDENGDSSEDGGD-SSESSSEDESEDGDENEEDDEDEDDD- 697 Query: 1455 SPSDEELANLLEEGEDGEDEDSDADEEVELILGDTDSSDNS 1495 E+ ++ ED +S+ GD+ SD++ Sbjct: 698 -----------EDDDEDEDNESEGSSSSSSSSGDSSDSDSN 727 Score = 57.8 bits (138), Expect = 8e-08 Identities = 36/97 (37%), Positives = 51/97 (52%), Gaps = 12/97 (12%) Query: 1405 EEEEQEEEDDDEDDDDTDDLDELDTDQLLEAELEEDDNNENAGED-GDNDFSPSDEELAN 1463 + + + EEDD+ED+DD D E E EEDD N ++ ED GD+ S S++E + Sbjct: 635 QSKSESEEDDEEDEDDED-----------EDEEEEDDENGDSSEDGGDSSESSSEDESED 683 Query: 1464 LLEEGEDGEDEDSDADEEVELILGDTDSSDNSDLEDD 1500 E ED EDED D D++ + SS +S D Sbjct: 684 GDENEEDDEDEDDDEDDDEDEDNESEGSSSSSSSSGD 720 >gi|7657671 upstream binding transcription factor, RNA polymerase I isoform a [Homo sapiens] Length = 764 Score = 61.2 bits (147), Expect = 7e-09 Identities = 32/101 (31%), Positives = 56/101 (55%), Gaps = 13/101 (12%) Query: 1395 AEDEDEEEDQEEEEQEEEDDDEDDDDTDDLDELDTDQLLEAELEEDDNNENAGEDGDNDF 1454 +E++DEE++ +E+E EEE+DDE+ D ++D + ++ E E E+ D NE ED D+D Sbjct: 677 SEEDDEEDEDDEDEDEEEEDDENGDSSEDGGD-SSESSSEDESEDGDENEEDDEDEDDD- 734 Query: 1455 SPSDEELANLLEEGEDGEDEDSDADEEVELILGDTDSSDNS 1495 E+ ++ ED +S+ GD+ SD++ Sbjct: 735 -----------EDDDEDEDNESEGSSSSSSSSGDSSDSDSN 764 Score = 57.8 bits (138), Expect = 8e-08 Identities = 36/97 (37%), Positives = 51/97 (52%), Gaps = 12/97 (12%) Query: 1405 EEEEQEEEDDDEDDDDTDDLDELDTDQLLEAELEEDDNNENAGED-GDNDFSPSDEELAN 1463 + + + EEDD+ED+DD D E E EEDD N ++ ED GD+ S S++E + Sbjct: 672 QSKSESEEDDEEDEDDED-----------EDEEEEDDENGDSSEDGGDSSESSSEDESED 720 Query: 1464 LLEEGEDGEDEDSDADEEVELILGDTDSSDNSDLEDD 1500 E ED EDED D D++ + SS +S D Sbjct: 721 GDENEEDDEDEDDDEDDDEDEDNESEGSSSSSSSSGD 757 >gi|239756368 PREDICTED: similar to acidic (leucine-rich) nuclear phosphoprotein 32 family, member B [Homo sapiens] Length = 272 Score = 60.8 bits (146), Expect = 9e-09 Identities = 35/113 (30%), Positives = 62/113 (54%), Gaps = 9/113 (7%) Query: 1387 YEVGRQRLAEDEDEEEDQEEEEQEEEDDDEDDDDTDDLDELDTDQLLEAELEEDDNNENA 1446 Y+ Q + + + + ++EE++EE +DE D + +D +E + D+ EED++ + Sbjct: 168 YDPEDQEAPDSDAQVDGVDKEEEDEEGEDEKDXENEDGEEEELDE------EEDEDEDVE 221 Query: 1447 GEDGDNDFSPSDEELANLLEEGEDGEDEDSDADEEVELILGDTDSSDNSDLED 1499 G+D ++ S +EE L++ ED EDED D +EE E G+ + D ED Sbjct: 222 GDDDKDEVSEEEEEFG--LDKDEDDEDEDEDEEEE-ESGKGENRKRETDDEED 271 Score = 46.2 bits (108), Expect = 2e-04 Identities = 29/98 (29%), Positives = 50/98 (51%), Gaps = 12/98 (12%) Query: 1403 DQEEEEQEEEDDDEDDDDTDDLDELDTDQLLEAELEEDDNNENAGEDGDNDFSPSDEELA 1462 D E++E + D D D ++ DE E E E+D NE+ E+ ++ DE++ Sbjct: 169 DPEDQEAPDSDAQVDGVDKEEEDE-------EGEDEKDXENEDGEEEELDEEEDEDEDV- 220 Query: 1463 NLLEEGEDGEDEDSDADEEVELILGDTDSSDNSDLEDD 1500 EG+D +DE S+ +EE L + D ++ D E++ Sbjct: 221 ----EGDDDKDEVSEEEEEFGLDKDEDDEDEDEDEEEE 254 Score = 37.0 bits (84), Expect = 0.14 Identities = 29/92 (31%), Positives = 50/92 (54%), Gaps = 16/92 (17%) Query: 1417 DDDDTDDLDELDTDQLLEAELEEDDNNENAGEDGDNDFSPSDEELANLLEEGEDGE-DED 1475 D D +D + D+D ++ +E+++ E GED +++ N E+GE+ E DE+ Sbjct: 166 DTYDPEDQEAPDSDAQVDGVDKEEEDEE--GED--------EKDXEN--EDGEEEELDEE 213 Query: 1476 SDADEEVELILGDTDSSDNSDLEDDIILSLNE 1507 D DE+VE GD D + S+ E++ L +E Sbjct: 214 EDEDEDVE---GDDDKDEVSEEEEEFGLDKDE 242 >gi|239750893 PREDICTED: similar to acidic (leucine-rich) nuclear phosphoprotein 32 family, member B [Homo sapiens] Length = 272 Score = 60.8 bits (146), Expect = 9e-09 Identities = 35/113 (30%), Positives = 62/113 (54%), Gaps = 9/113 (7%) Query: 1387 YEVGRQRLAEDEDEEEDQEEEEQEEEDDDEDDDDTDDLDELDTDQLLEAELEEDDNNENA 1446 Y+ Q + + + + ++EE++EE +DE D + +D +E + D+ EED++ + Sbjct: 168 YDPEDQEAPDSDAQVDGVDKEEEDEEGEDEKDXENEDGEEEELDE------EEDEDEDVE 221 Query: 1447 GEDGDNDFSPSDEELANLLEEGEDGEDEDSDADEEVELILGDTDSSDNSDLED 1499 G+D ++ S +EE L++ ED EDED D +EE E G+ + D ED Sbjct: 222 GDDDKDEVSEEEEEFG--LDKDEDDEDEDEDEEEE-ESGKGENRKRETDDEED 271 Score = 46.2 bits (108), Expect = 2e-04 Identities = 29/98 (29%), Positives = 50/98 (51%), Gaps = 12/98 (12%) Query: 1403 DQEEEEQEEEDDDEDDDDTDDLDELDTDQLLEAELEEDDNNENAGEDGDNDFSPSDEELA 1462 D E++E + D D D ++ DE E E E+D NE+ E+ ++ DE++ Sbjct: 169 DPEDQEAPDSDAQVDGVDKEEEDE-------EGEDEKDXENEDGEEEELDEEEDEDEDV- 220 Query: 1463 NLLEEGEDGEDEDSDADEEVELILGDTDSSDNSDLEDD 1500 EG+D +DE S+ +EE L + D ++ D E++ Sbjct: 221 ----EGDDDKDEVSEEEEEFGLDKDEDDEDEDEDEEEE 254 Score = 37.0 bits (84), Expect = 0.14 Identities = 29/92 (31%), Positives = 50/92 (54%), Gaps = 16/92 (17%) Query: 1417 DDDDTDDLDELDTDQLLEAELEEDDNNENAGEDGDNDFSPSDEELANLLEEGEDGE-DED 1475 D D +D + D+D ++ +E+++ E GED +++ N E+GE+ E DE+ Sbjct: 166 DTYDPEDQEAPDSDAQVDGVDKEEEDEE--GED--------EKDXEN--EDGEEEELDEE 213 Query: 1476 SDADEEVELILGDTDSSDNSDLEDDIILSLNE 1507 D DE+VE GD D + S+ E++ L +E Sbjct: 214 EDEDEDVE---GDDDKDEVSEEEEEFGLDKDE 242 >gi|214010181 amyloid beta (A4) precursor-like protein 2 isoform 2 [Homo sapiens] Length = 751 Score = 60.1 bits (144), Expect = 2e-08 Identities = 33/95 (34%), Positives = 50/95 (52%), Gaps = 7/95 (7%) Query: 1398 EDEEEDQEEEEQEEEDDDEDDDDTDDLDELDTDQLLEAELEEDDNNENAGEDGDND---- 1453 E+EEED+EEEE+E+E++D D ++ E D + EA ++EDD +E GE+ D Sbjct: 215 EEEEEDEEEEEEEDEEEDYDVYKSEFPTEADLEDFTEAAVDEDDEDEEEGEEVVEDRDYY 274 Query: 1454 ---FSPSDEELANLLEEGEDGEDEDSDADEEVELI 1485 F D N E G DG D + +V+ + Sbjct: 275 YDTFKGDDYNEENPTEPGSDGTMSDKEITHDVKAV 309 Score = 36.6 bits (83), Expect = 0.19 Identities = 24/86 (27%), Positives = 42/86 (48%), Gaps = 27/86 (31%) Query: 1405 EEEEQEEEDDDEDDDDTDDLDELDTDQLLEAELEEDDNNENAGEDGDNDFSPSDEELANL 1464 +EEE+E+E+++E++D+ +D D ++ EA+LE DF+ Sbjct: 214 KEEEEEDEEEEEEEDEEEDYDVYKSEFPTEADLE--------------DFT--------- 250 Query: 1465 LEEGEDGEDEDSDADEEVELILGDTD 1490 E DED + +EE E ++ D D Sbjct: 251 ----EAAVDEDDEDEEEGEEVVEDRD 272 Score = 35.0 bits (79), Expect = 0.55 Identities = 25/98 (25%), Positives = 46/98 (46%), Gaps = 28/98 (28%) Query: 1389 VGRQRLAEDEDEEEDQEEEEQ-----------------------EEEDDDEDDDDTDDLD 1425 V ++ EDE+EEE+++EEE E+++D+E+ ++ + Sbjct: 212 VSKEEEEEDEEEEEEEDEEEDYDVYKSEFPTEADLEDFTEAAVDEDDEDEEEGEEVVE-- 269 Query: 1426 ELDTDQLLEAELEEDDNNENAGEDGDNDFSPSDEELAN 1463 D D + +D N EN E G +D + SD+E+ + Sbjct: 270 --DRDYYYDTFKGDDYNEENPTEPG-SDGTMSDKEITH 304 >gi|4502147 amyloid beta (A4) precursor-like protein 2 isoform 1 [Homo sapiens] Length = 763 Score = 60.1 bits (144), Expect = 2e-08 Identities = 33/95 (34%), Positives = 50/95 (52%), Gaps = 7/95 (7%) Query: 1398 EDEEEDQEEEEQEEEDDDEDDDDTDDLDELDTDQLLEAELEEDDNNENAGEDGDND---- 1453 E+EEED+EEEE+E+E++D D ++ E D + EA ++EDD +E GE+ D Sbjct: 215 EEEEEDEEEEEEEDEEEDYDVYKSEFPTEADLEDFTEAAVDEDDEDEEEGEEVVEDRDYY 274 Query: 1454 ---FSPSDEELANLLEEGEDGEDEDSDADEEVELI 1485 F D N E G DG D + +V+ + Sbjct: 275 YDTFKGDDYNEENPTEPGSDGTMSDKEITHDVKAV 309 Score = 36.6 bits (83), Expect = 0.19 Identities = 24/86 (27%), Positives = 42/86 (48%), Gaps = 27/86 (31%) Query: 1405 EEEEQEEEDDDEDDDDTDDLDELDTDQLLEAELEEDDNNENAGEDGDNDFSPSDEELANL 1464 +EEE+E+E+++E++D+ +D D ++ EA+LE DF+ Sbjct: 214 KEEEEEDEEEEEEEDEEEDYDVYKSEFPTEADLE--------------DFT--------- 250 Query: 1465 LEEGEDGEDEDSDADEEVELILGDTD 1490 E DED + +EE E ++ D D Sbjct: 251 ----EAAVDEDDEDEEEGEEVVEDRD 272 Score = 35.0 bits (79), Expect = 0.55 Identities = 25/98 (25%), Positives = 46/98 (46%), Gaps = 28/98 (28%) Query: 1389 VGRQRLAEDEDEEEDQEEEEQ-----------------------EEEDDDEDDDDTDDLD 1425 V ++ EDE+EEE+++EEE E+++D+E+ ++ + Sbjct: 212 VSKEEEEEDEEEEEEEDEEEDYDVYKSEFPTEADLEDFTEAAVDEDDEDEEEGEEVVE-- 269 Query: 1426 ELDTDQLLEAELEEDDNNENAGEDGDNDFSPSDEELAN 1463 D D + +D N EN E G +D + SD+E+ + Sbjct: 270 --DRDYYYDTFKGDDYNEENPTEPG-SDGTMSDKEITH 304 >gi|214010183 amyloid beta (A4) precursor-like protein 2 isoform 3 [Homo sapiens] Length = 695 Score = 59.7 bits (143), Expect = 2e-08 Identities = 33/94 (35%), Positives = 50/94 (53%), Gaps = 7/94 (7%) Query: 1398 EDEEEDQEEEEQEEEDDDEDDDDTDDLDELDTDQLLEAELEEDDNNENAGEDGDND---- 1453 E+EEED+EEEE+E+E++D D ++ E D + EA ++EDD +E GE+ D Sbjct: 215 EEEEEDEEEEEEEDEEEDYDVYKSEFPTEADLEDFTEAAVDEDDEDEEEGEEVVEDRDYY 274 Query: 1454 ---FSPSDEELANLLEEGEDGEDEDSDADEEVEL 1484 F D N E G DG D + +V++ Sbjct: 275 YDTFKGDDYNEENPTEPGSDGTMSDKEITHDVKV 308 Score = 36.6 bits (83), Expect = 0.19 Identities = 24/86 (27%), Positives = 42/86 (48%), Gaps = 27/86 (31%) Query: 1405 EEEEQEEEDDDEDDDDTDDLDELDTDQLLEAELEEDDNNENAGEDGDNDFSPSDEELANL 1464 +EEE+E+E+++E++D+ +D D ++ EA+LE DF+ Sbjct: 214 KEEEEEDEEEEEEEDEEEDYDVYKSEFPTEADLE--------------DFT--------- 250 Query: 1465 LEEGEDGEDEDSDADEEVELILGDTD 1490 E DED + +EE E ++ D D Sbjct: 251 ----EAAVDEDDEDEEEGEEVVEDRD 272 Score = 35.0 bits (79), Expect = 0.55 Identities = 25/98 (25%), Positives = 46/98 (46%), Gaps = 28/98 (28%) Query: 1389 VGRQRLAEDEDEEEDQEEEEQ-----------------------EEEDDDEDDDDTDDLD 1425 V ++ EDE+EEE+++EEE E+++D+E+ ++ + Sbjct: 212 VSKEEEEEDEEEEEEEDEEEDYDVYKSEFPTEADLEDFTEAAVDEDDEDEEEGEEVVE-- 269 Query: 1426 ELDTDQLLEAELEEDDNNENAGEDGDNDFSPSDEELAN 1463 D D + +D N EN E G +D + SD+E+ + Sbjct: 270 --DRDYYYDTFKGDDYNEENPTEPG-SDGTMSDKEITH 304 >gi|61676188 HECT, UBA and WWE domain containing 1 [Homo sapiens] Length = 4374 Score = 58.5 bits (140), Expect = 5e-08 Identities = 26/51 (50%), Positives = 39/51 (76%) Query: 1396 EDEDEEEDQEEEEQEEEDDDEDDDDTDDLDELDTDQLLEAELEEDDNNENA 1446 EDED+ +D+EEEE+E+E+DD++DD+ ++ DE D D E EL+ED + NA Sbjct: 2426 EDEDDSQDEEEEEEEDEEDDQEDDEGEEGDEDDDDDGSEMELDEDYPDMNA 2476 Score = 49.3 bits (116), Expect = 3e-05 Identities = 31/107 (28%), Positives = 51/107 (47%), Gaps = 18/107 (16%) Query: 1400 EEEDQEEEEQEEEDDDEDDDDTDDLDELDTDQLLEAELEEDDNNENAGEDGDNDFSPSDE 1459 + ED+EE QEE+ ++D+ D DE + E E EEDD ++ GE+GD D Sbjct: 2408 DPEDEEEHTQEEDSSGSNEDEDDSQDEEEE----EEEDEEDDQEDDEGEEGDED------ 2457 Query: 1460 ELANLLEEGEDGEDEDSDADEEVELILGDTDSSDNSDLEDDIILSLN 1506 + +DG + + D D ++ + D EDD+I+ + Sbjct: 2458 -------DDDDGSEMELDEDYP-DMNASPLVRFERFDREDDLIIEFD 2496 Score = 37.7 bits (86), Expect = 0.085 Identities = 20/64 (31%), Positives = 34/64 (53%) Query: 1396 EDEDEEEDQEEEEQEEEDDDEDDDDTDDLDELDTDQLLEAELEEDDNNENAGEDGDNDFS 1455 ++ED++ED E EE +E+DDD+ + D D D + E D ++ + DN FS Sbjct: 2441 DEEDDQEDDEGEEGDEDDDDDGSEMELDEDYPDMNASPLVRFERFDREDDLIIEFDNMFS 2500 Query: 1456 PSDE 1459 + + Sbjct: 2501 SATD 2504 Score = 32.3 bits (72), Expect = 3.6 Identities = 33/116 (28%), Positives = 47/116 (40%), Gaps = 30/116 (25%) Query: 1409 QEEEDDDEDDDDTDDLDELD----TDQLLEAELEEDDNNENA------------------ 1446 QE + ++E +D D+L E D ++ + ED++ E+ Sbjct: 2340 QEMQVENELEDLIDELLERDGGSGNSTIIVSRSGEDESQEDVLMDEAPSNLSQASTLQAN 2399 Query: 1447 GEDGDNDFSPSDEELANLLEEGEDG--EDEDSDADEEVELILGDTDSSDNSDLEDD 1500 ED N P DEE + EE G EDED DEE E + + D EDD Sbjct: 2400 REDSMNILDPEDEE-EHTQEEDSSGSNEDEDDSQDEEEE-----EEEDEEDDQEDD 2449 >gi|155030232 proline, glutamic acid and leucine rich protein 1 [Homo sapiens] Length = 1130 Score = 57.8 bits (138), Expect = 8e-08 Identities = 33/89 (37%), Positives = 57/89 (64%), Gaps = 12/89 (13%) Query: 1395 AEDEDEEEDQEEEEQEEEDDDEDDDDTDDLDELDTDQLLEAELEEDDNNENAGEDGDNDF 1454 + DE+EEE++EEEE+EEE+++E++D + +E D ++ E E EE+ E+ + +F Sbjct: 885 SSDEEEEEEEEEEEEEEEEEEEEEDFEE--EEEDEEEYFEEEEEEE-------EEFEEEF 935 Query: 1455 SPSDEELANLLEEGEDGEDEDSDADEEVE 1483 +EE L EE E+ ++E+ + EEVE Sbjct: 936 ---EEEEGELEEEEEEEDEEEEEELEEVE 961 Score = 49.7 bits (117), Expect = 2e-05 Identities = 27/77 (35%), Positives = 47/77 (61%), Gaps = 6/77 (7%) Query: 1396 EDEDEEEDQEEEEQEEEDDDEDDDDTDDLDELDTDQLLEAELEEDDNNENAGEDGDNDFS 1455 E+E+EEE++EEEE+E+ +++E+D++ +E + ++ E E EE++ E+ + Sbjct: 894 EEEEEEEEEEEEEEEDFEEEEEDEEEYFEEEEEEEEEFEEEFEEEEGELEEEEEEE---- 949 Query: 1456 PSDEELANLLEEGEDGE 1472 DEE LEE ED E Sbjct: 950 --DEEEEEELEEVEDLE 964 Score = 48.1 bits (113), Expect = 6e-05 Identities = 25/80 (31%), Positives = 48/80 (60%) Query: 1396 EDEDEEEDQEEEEQEEEDDDEDDDDTDDLDELDTDQLLEAELEEDDNNENAGEDGDNDFS 1455 E+E+EEE++EEEE++ E+++ED+++ + +E + ++ E EE+ E E+ D + Sbjct: 895 EEEEEEEEEEEEEEDFEEEEEDEEEYFEEEEEEEEEFEEEFEEEEGELEEEEEEEDEEEE 954 Query: 1456 PSDEELANLLEEGEDGEDED 1475 EE+ +L GE E+ Sbjct: 955 EELEEVEDLEFGTAGGEVEE 974 Score = 38.5 bits (88), Expect = 0.050 Identities = 19/68 (27%), Positives = 36/68 (52%) Query: 1434 EAELEEDDNNENAGEDGDNDFSPSDEELANLLEEGEDGEDEDSDADEEVELILGDTDSSD 1493 E E EE++ E E+ + DF +E+ EE E+ E+E + EE E L + + + Sbjct: 890 EEEEEEEEEEEEEEEEEEEDFEEEEEDEEEYFEEEEEEEEEFEEEFEEEEGELEEEEEEE 949 Query: 1494 NSDLEDDI 1501 + + E+++ Sbjct: 950 DEEEEEEL 957 Score = 38.5 bits (88), Expect = 0.050 Identities = 32/107 (29%), Positives = 49/107 (45%), Gaps = 23/107 (21%) Query: 1396 EDEDE---EEDQEEEEQEEEDDDEDDDDTDDLDELDTDQLLEAELEEDDNNENAGEDGDN 1452 EDE+E EE++EEEE EEE ++E+ + ++ +E D ++ E E ED AG + + Sbjct: 915 EDEEEYFEEEEEEEEEFEEEFEEEEGELEEEEEEEDEEEEEELEEVEDLEFGTAGGEVEE 974 Query: 1453 DFSP--------------------SDEELANLLEEGEDGEDEDSDAD 1479 P + E LLE E G +E+ AD Sbjct: 975 GAPPPPTLPPALPPPESPPKVQPEPEPEPGLLLEVEEPGTEEERGAD 1021 >gi|4503257 death-domain associated protein isoform a [Homo sapiens] Length = 740 Score = 55.5 bits (132), Expect = 4e-07 Identities = 25/61 (40%), Positives = 41/61 (67%) Query: 1396 EDEDEEEDQEEEEQEEEDDDEDDDDTDDLDELDTDQLLEAELEEDDNNENAGEDGDNDFS 1455 +DED+EE EEEE+EEE+++E+ D+++ ++L+ Q + + EE+D E A D D S Sbjct: 436 DDEDDEESDEEEEEEEEEEEEEATDSEEEEDLEQMQEGQEDDEEEDEEEEAAAGKDGDKS 495 Query: 1456 P 1456 P Sbjct: 496 P 496 Score = 52.0 bits (123), Expect = 4e-06 Identities = 27/64 (42%), Positives = 44/64 (68%), Gaps = 5/64 (7%) Query: 1391 RQRLAEDEDEEEDQEEEEQEEEDDDE--DDDDTDDLDELDTDQLLEAELEEDDNNE-NAG 1447 R +++DEE D+EEEE+EEE+++E D ++ +DL+++ Q E + EED+ E AG Sbjct: 432 RAETDDEDDEESDEEEEEEEEEEEEEATDSEEEEDLEQMQEGQ--EDDEEEDEEEEAAAG 489 Query: 1448 EDGD 1451 +DGD Sbjct: 490 KDGD 493 Score = 45.8 bits (107), Expect = 3e-04 Identities = 30/105 (28%), Positives = 52/105 (49%), Gaps = 37/105 (35%) Query: 1395 AEDEDEEEDQEEEEQEEEDDDEDDDDTDDLDELDTDQLLEAELEEDDNNENAGEDGDNDF 1454 AE +DE++++ +EE+EEE+++E+++ TD +E EED Sbjct: 433 AETDDEDDEESDEEEEEEEEEEEEEATD------------SEEEED-------------- 466 Query: 1455 SPSDEELANLLEEGEDGEDEDSDADEEVELILG-DTDSSDNSDLE 1498 LE+ ++G+++D + DEE E G D D S S L+ Sbjct: 467 ----------LEQMQEGQEDDEEEDEEEEAAAGKDGDKSPMSSLQ 501 Score = 35.8 bits (81), Expect = 0.32 Identities = 26/112 (23%), Positives = 46/112 (41%), Gaps = 6/112 (5%) Query: 1389 VGRQRLAEDEDEEEDQEEEEQEEEDDDEDDDDTDDLDELDTDQLLEAELEEDDNNENAGE 1448 + + + +D+ EE ++++ + DT + LD+ + + + + E Sbjct: 376 ISKYAMLQDKSEEGERKKRRARLQGTSSHSADTPEAS-LDSGEGPSGMASQGCPSASRAE 434 Query: 1449 DGDNDFSPSDEELANLLEEGEDGEDEDSDADEEVELILGDTDSSDNSDLEDD 1500 D D SDEE EE E+ E+E+ D E E L D E+D Sbjct: 435 TDDEDDEESDEE-----EEEEEEEEEEEATDSEEEEDLEQMQEGQEDDEEED 481 >gi|215422388 death-domain associated protein isoform a [Homo sapiens] Length = 740 Score = 55.5 bits (132), Expect = 4e-07 Identities = 25/61 (40%), Positives = 41/61 (67%) Query: 1396 EDEDEEEDQEEEEQEEEDDDEDDDDTDDLDELDTDQLLEAELEEDDNNENAGEDGDNDFS 1455 +DED+EE EEEE+EEE+++E+ D+++ ++L+ Q + + EE+D E A D D S Sbjct: 436 DDEDDEESDEEEEEEEEEEEEEATDSEEEEDLEQMQEGQEDDEEEDEEEEAAAGKDGDKS 495 Query: 1456 P 1456 P Sbjct: 496 P 496 Score = 52.0 bits (123), Expect = 4e-06 Identities = 27/64 (42%), Positives = 44/64 (68%), Gaps = 5/64 (7%) Query: 1391 RQRLAEDEDEEEDQEEEEQEEEDDDE--DDDDTDDLDELDTDQLLEAELEEDDNNE-NAG 1447 R +++DEE D+EEEE+EEE+++E D ++ +DL+++ Q E + EED+ E AG Sbjct: 432 RAETDDEDDEESDEEEEEEEEEEEEEATDSEEEEDLEQMQEGQ--EDDEEEDEEEEAAAG 489 Query: 1448 EDGD 1451 +DGD Sbjct: 490 KDGD 493 Score = 45.8 bits (107), Expect = 3e-04 Identities = 30/105 (28%), Positives = 52/105 (49%), Gaps = 37/105 (35%) Query: 1395 AEDEDEEEDQEEEEQEEEDDDEDDDDTDDLDELDTDQLLEAELEEDDNNENAGEDGDNDF 1454 AE +DE++++ +EE+EEE+++E+++ TD +E EED Sbjct: 433 AETDDEDDEESDEEEEEEEEEEEEEATD------------SEEEED-------------- 466 Query: 1455 SPSDEELANLLEEGEDGEDEDSDADEEVELILG-DTDSSDNSDLE 1498 LE+ ++G+++D + DEE E G D D S S L+ Sbjct: 467 ----------LEQMQEGQEDDEEEDEEEEAAAGKDGDKSPMSSLQ 501 Score = 35.8 bits (81), Expect = 0.32 Identities = 26/112 (23%), Positives = 46/112 (41%), Gaps = 6/112 (5%) Query: 1389 VGRQRLAEDEDEEEDQEEEEQEEEDDDEDDDDTDDLDELDTDQLLEAELEEDDNNENAGE 1448 + + + +D+ EE ++++ + DT + LD+ + + + + E Sbjct: 376 ISKYAMLQDKSEEGERKKRRARLQGTSSHSADTPEAS-LDSGEGPSGMASQGCPSASRAE 434 Query: 1449 DGDNDFSPSDEELANLLEEGEDGEDEDSDADEEVELILGDTDSSDNSDLEDD 1500 D D SDEE EE E+ E+E+ D E E L D E+D Sbjct: 435 TDDEDDEESDEE-----EEEEEEEEEEEATDSEEEEDLEQMQEGQEDDEEED 481 >gi|215422366 death-domain associated protein isoform b [Homo sapiens] Length = 752 Score = 55.5 bits (132), Expect = 4e-07 Identities = 25/61 (40%), Positives = 41/61 (67%) Query: 1396 EDEDEEEDQEEEEQEEEDDDEDDDDTDDLDELDTDQLLEAELEEDDNNENAGEDGDNDFS 1455 +DED+EE EEEE+EEE+++E+ D+++ ++L+ Q + + EE+D E A D D S Sbjct: 448 DDEDDEESDEEEEEEEEEEEEEATDSEEEEDLEQMQEGQEDDEEEDEEEEAAAGKDGDKS 507 Query: 1456 P 1456 P Sbjct: 508 P 508 Score = 52.0 bits (123), Expect = 4e-06 Identities = 27/64 (42%), Positives = 44/64 (68%), Gaps = 5/64 (7%) Query: 1391 RQRLAEDEDEEEDQEEEEQEEEDDDE--DDDDTDDLDELDTDQLLEAELEEDDNNE-NAG 1447 R +++DEE D+EEEE+EEE+++E D ++ +DL+++ Q E + EED+ E AG Sbjct: 444 RAETDDEDDEESDEEEEEEEEEEEEEATDSEEEEDLEQMQEGQ--EDDEEEDEEEEAAAG 501 Query: 1448 EDGD 1451 +DGD Sbjct: 502 KDGD 505 Score = 45.8 bits (107), Expect = 3e-04 Identities = 30/105 (28%), Positives = 52/105 (49%), Gaps = 37/105 (35%) Query: 1395 AEDEDEEEDQEEEEQEEEDDDEDDDDTDDLDELDTDQLLEAELEEDDNNENAGEDGDNDF 1454 AE +DE++++ +EE+EEE+++E+++ TD +E EED Sbjct: 445 AETDDEDDEESDEEEEEEEEEEEEEATD------------SEEEED-------------- 478 Query: 1455 SPSDEELANLLEEGEDGEDEDSDADEEVELILG-DTDSSDNSDLE 1498 LE+ ++G+++D + DEE E G D D S S L+ Sbjct: 479 ----------LEQMQEGQEDDEEEDEEEEAAAGKDGDKSPMSSLQ 513 Score = 35.8 bits (81), Expect = 0.32 Identities = 26/112 (23%), Positives = 46/112 (41%), Gaps = 6/112 (5%) Query: 1389 VGRQRLAEDEDEEEDQEEEEQEEEDDDEDDDDTDDLDELDTDQLLEAELEEDDNNENAGE 1448 + + + +D+ EE ++++ + DT + LD+ + + + + E Sbjct: 388 ISKYAMLQDKSEEGERKKRRARLQGTSSHSADTPEAS-LDSGEGPSGMASQGCPSASRAE 446 Query: 1449 DGDNDFSPSDEELANLLEEGEDGEDEDSDADEEVELILGDTDSSDNSDLEDD 1500 D D SDEE EE E+ E+E+ D E E L D E+D Sbjct: 447 TDDEDDEESDEE-----EEEEEEEEEEEATDSEEEEDLEQMQEGQEDDEEED 493 >gi|17975763 myelin transcription factor 1 [Homo sapiens] Length = 1121 Score = 55.5 bits (132), Expect = 4e-07 Identities = 33/123 (26%), Positives = 62/123 (50%), Gaps = 24/123 (19%) Query: 1394 LAEDEDEEEDQEEEEQEEEDDDEDDDDTDDLDELDTDQLLEAELEEDDNNENAGED---- 1449 L+ +E++EE++EEEE+EEED++E++++ ++ +E + ++ E E EE++ E A D Sbjct: 255 LSHEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEAAPDVIFQ 314 Query: 1450 ---------------GDNDFSPSDEELANLLEEGEDGEDEDSDADEEVELILGDTDSSDN 1494 G SP E + +D +DED+ + + TD S+ Sbjct: 315 EDTSHTSAQKAPELRGPESPSPKPEYSVIVEVRSDDDKDEDTHSRKSTV-----TDESEM 369 Query: 1495 SDL 1497 D+ Sbjct: 370 QDM 372 Score = 35.0 bits (79), Expect = 0.55 Identities = 25/111 (22%), Positives = 49/111 (44%) Query: 1390 GRQRLAEDEDEEEDQEEEEQEEEDDDEDDDDTDDLDELDTDQLLEAELEEDDNNENAGED 1449 G L ++ E EE E+ ED ++ ++ + L LE+ + E++ + Sbjct: 193 GIVHLLQEAAEGAASEEGEKGLFIQPEDAEEVVEVTTERSQDLCPQSLEDAASEESSKQK 252 Query: 1450 GDNDFSPSDEELANLLEEGEDGEDEDSDADEEVELILGDTDSSDNSDLEDD 1500 G DEE EE E+ E+E+ + +EE E + + + + E++ Sbjct: 253 GILSHEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEEEEEEE 303 Score = 34.7 bits (78), Expect = 0.72 Identities = 27/114 (23%), Positives = 51/114 (44%), Gaps = 3/114 (2%) Query: 1392 QRLAEDEDEEEDQEEEEQEEEDDDEDDDDTDDLDELDTDQLLEAELEEDDNNEN---AGE 1448 Q AE EE ++ + ED +E + T + + Q LE E+ + + + E Sbjct: 199 QEAAEGAASEEGEKGLFIQPEDAEEVVEVTTERSQDLCPQSLEDAASEESSKQKGILSHE 258 Query: 1449 DGDNDFSPSDEELANLLEEGEDGEDEDSDADEEVELILGDTDSSDNSDLEDDII 1502 + D + +EE EE E+ E+E+ + +EE E + + + + D+I Sbjct: 259 EEDEEEEEEEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEAAPDVI 312 >gi|195546902 suppressor of Ty 5 homolog isoform b [Homo sapiens] Length = 1083 Score = 54.7 bits (130), Expect = 7e-07 Identities = 41/127 (32%), Positives = 62/127 (48%), Gaps = 15/127 (11%) Query: 1390 GRQRLAEDEDEEEDQEEEEQEEEDDDEDDDDTDD--------LDELDTDQLLEAELEEDD 1441 G ++ E EDEEE++EEEE +EE+++EDDD LDE D D E E + +D Sbjct: 35 GSEKEEEPEDEEEEEEEEEYDEEEEEEDDDRPPKKPRHGGFILDEADVDDEYEDEDQWED 94 Query: 1442 NNENAGEDGDN-DFSPSDEE------LANLLEEGEDGEDEDSDADEEVELILGDTDSSDN 1494 E+ E N D DE+ L NL + + E + + + +G+T + Sbjct: 95 GAEDILEKASNIDNVVLDEDRSGARRLQNLWRDQREEELGEYYMKKYAKSSVGETVYGGS 154 Query: 1495 SDLEDDI 1501 +L DDI Sbjct: 155 DELSDDI 161 Score = 40.0 bits (92), Expect = 0.017 Identities = 28/114 (24%), Positives = 51/114 (44%), Gaps = 7/114 (6%) Query: 1394 LAEDEDEEEDQEEEEQEEEDDDEDDDDTDDLDELDTDQLLEAELEEDDNNENA----GED 1449 +++ ED +EE+ + D +E + D + +++ E E EE++ E E+ Sbjct: 1 MSDSEDSNFSEEEDSERSSDGEEAEVDEERRSAAGSEKEEEPEDEEEEEEEEEYDEEEEE 60 Query: 1450 GDNDFSPSDEELANLLEEGEDGEDEDSDAD---EEVELILGDTDSSDNSDLEDD 1500 D+D P + + D +DE D D + E IL + DN L++D Sbjct: 61 EDDDRPPKKPRHGGFILDEADVDDEYEDEDQWEDGAEDILEKASNIDNVVLDED 114 Score = 36.6 bits (83), Expect = 0.19 Identities = 27/106 (25%), Positives = 54/106 (50%), Gaps = 22/106 (20%) Query: 1388 EVGRQRLAEDEDEEEDQE-------EEEQEEEDDDEDDDD---TDDLDELDTDQ------ 1431 E +R ++ E+ E D+E E+E+E ED++E++++ ++ +E D D+ Sbjct: 12 EEDSERSSDGEEAEVDEERRSAAGSEKEEEPEDEEEEEEEEEYDEEEEEEDDDRPPKKPR 71 Query: 1432 -----LLEAELEEDDNNENAGEDGDNDFSPSDEELAN-LLEEGEDG 1471 L EA+++++ +E+ EDG D + N +L+E G Sbjct: 72 HGGFILDEADVDDEYEDEDQWEDGAEDILEKASNIDNVVLDEDRSG 117 >gi|114155142 nuclear pore complex-associated protein TPR [Homo sapiens] Length = 2363 Score = 54.3 bits (129), Expect = 9e-07 Identities = 33/87 (37%), Positives = 47/87 (54%), Gaps = 11/87 (12%) Query: 1396 EDEDEEEDQEEEEQEEEDDDEDDDDTDDLDELDTDQLLEAELEEDDNNENAGEDGDNDFS 1455 + +DEEED +E + E ED +ED++D DD DE DT E E D+NE G ND Sbjct: 1947 DSDDEEEDDDENDGEHEDYEEDEEDDDD-DEDDTGMGDEGE----DSNEGTGSADGNDGY 2001 Query: 1456 PSDEELANLLEEGEDGEDEDSDADEEV 1482 +D+ EG DG D ++ +E + Sbjct: 2002 EADD------AEGGDGTDPGTETEESM 2022 Score = 38.9 bits (89), Expect = 0.038 Identities = 27/107 (25%), Positives = 45/107 (42%), Gaps = 12/107 (11%) Query: 1402 EDQEEEEQE--------EEDDDEDDDDTDDLDELDTDQLLEAELEEDDNNENAGE----D 1449 ED EE Q + D D + D +++++ EE+D++EN GE + Sbjct: 1907 EDSEETSQSLQIDLGPLQSDQQTTTSSQDGQGKGDDVIVIDSDDEEEDDDENDGEHEDYE 1966 Query: 1450 GDNDFSPSDEELANLLEEGEDGEDEDSDADEEVELILGDTDSSDNSD 1496 D + DE+ + +EGED + AD D + D +D Sbjct: 1967 EDEEDDDDDEDDTGMGDEGEDSNEGTGSADGNDGYEADDAEGGDGTD 2013 Score = 33.5 bits (75), Expect = 1.6 Identities = 29/113 (25%), Positives = 46/113 (40%), Gaps = 19/113 (16%) Query: 1399 DEEEDQEEEEQEEEDDDEDD--------DDTDDLDELDTDQLLEAEL---EEDDNNENAG 1447 +E D E E Q D +D D T D +T Q L+ +L + D + Sbjct: 1874 EESTDGEVETQVYNQDSQDSIGEGVTQGDYTPMEDSEETSQSLQIDLGPLQSDQQTTTSS 1933 Query: 1448 EDGDNDFSPSDEELANLLEEGEDGEDEDSDADEEVELILGDTDSSDNSDLEDD 1500 +DG D+ + ++ E+ +DE+ E+ E D D+ D EDD Sbjct: 1934 QDGQGK---GDDVIVIDSDDEEEDDDENDGEHEDYE-----EDEEDDDDDEDD 1978 >gi|16445033 ACRC protein [Homo sapiens] Length = 691 Score = 53.9 bits (128), Expect = 1e-06 Identities = 26/115 (22%), Positives = 58/115 (50%), Gaps = 9/115 (7%) Query: 1395 AEDEDEEEDQEEEEQEEEDDDEDDDDTDDLD---------ELDTDQLLEAELEEDDNNEN 1445 ++D D +D ++ ++ DD DD++DD D ++ D ++++ +D ++++ Sbjct: 183 SDDSDVPDDNSDDSSDDNSDDSSDDNSDDSDVPDDKSDDSDVPDDSSDDSDVPDDSSDDS 242 Query: 1446 AGEDGDNDFSPSDEELANLLEEGEDGEDEDSDADEEVELILGDTDSSDNSDLEDD 1500 D +D S + ++ ++ E +D D+ D+ + DSSD+S+ DD Sbjct: 243 EAPDDSSDDSEAPDDSSDDSEAPDDSSDDSEAPDDSSDDSEASDDSSDDSEASDD 297 Score = 53.1 bits (126), Expect = 2e-06 Identities = 28/106 (26%), Positives = 55/106 (51%), Gaps = 4/106 (3%) Query: 1395 AEDEDEEEDQEEEEQEEEDDDEDDDDTDDLDELDTDQLLEAELEEDDNNENAGEDGDNDF 1454 +E D+ D E + DD E DD D E D ++++ DDN++++ +D +D Sbjct: 146 SEAPDDNSDDSEAPDDNSDDSEAPDDNSDDSEAPDDNSDDSDVP-DDNSDDSSDDNSDDS 204 Query: 1455 SPSDEELANLLEEGEDGEDEDSDADEEVELILGDTDSSDNSDLEDD 1500 S + + +++ ++ D D D+ ++ ++ DSSD+S+ DD Sbjct: 205 SDDNSDDSDVPDDKSDDSDVPDDSSDDSDV---PDDSSDDSEAPDD 247 Score = 53.1 bits (126), Expect = 2e-06 Identities = 27/103 (26%), Positives = 54/103 (52%), Gaps = 1/103 (0%) Query: 1398 EDEEEDQEEEEQEEEDDDEDDDDTDDLDELDTDQLLEAELEEDDNNENAGEDGDNDFSPS 1457 +D +D + + + +D D DD +DD D D D ++E +D ++++ D +D S + Sbjct: 206 DDNSDDSDVPDDKSDDSDVPDDSSDDSDVPD-DSSDDSEAPDDSSDDSEAPDDSSDDSEA 264 Query: 1458 DEELANLLEEGEDGEDEDSDADEEVELILGDTDSSDNSDLEDD 1500 ++ ++ E +D D+ +D+ + DSSD+S+ DD Sbjct: 265 PDDSSDDSEAPDDSSDDSEASDDSSDDSEASDDSSDDSEAPDD 307 Score = 52.4 bits (124), Expect = 3e-06 Identities = 31/105 (29%), Positives = 49/105 (46%), Gaps = 4/105 (3%) Query: 1396 EDEDEEEDQEEEEQEEEDDDEDDDDTDDLDELDTDQLLEAELEEDDNNENAGEDGDNDFS 1455 E D+ D E + DD E DD D E D ++E DDN++++ DN Sbjct: 137 EVPDDNSDDSEAPDDNSDDSEAPDDNSDDSEAPDDNSDDSEAP-DDNSDDSDVPDDNSDD 195 Query: 1456 PSDEELANLLEEGEDGEDEDSDADEEVELILGDTDSSDNSDLEDD 1500 SD+ + ++ D D D ++ ++ DSSD+SD+ DD Sbjct: 196 SSDDNSDDSSDDNSDDSDVPDDKSDDSDV---PDDSSDDSDVPDD 237 Score = 52.4 bits (124), Expect = 3e-06 Identities = 26/102 (25%), Positives = 50/102 (49%) Query: 1399 DEEEDQEEEEQEEEDDDEDDDDTDDLDELDTDQLLEAELEEDDNNENAGEDGDNDFSPSD 1458 D+ D + + DD E DD+ D E D ++E +D ++++ D +D S + Sbjct: 226 DDSSDDSDVPDDSSDDSEAPDDSSDDSEAPDDSSDDSEAPDDSSDDSEAPDDSSDDSEAS 285 Query: 1459 EELANLLEEGEDGEDEDSDADEEVELILGDTDSSDNSDLEDD 1500 ++ ++ E +D D+ D++ + D SD+SD+ DD Sbjct: 286 DDSSDDSEASDDSSDDSEAPDDKSDDSDVPEDKSDDSDVPDD 327 Score = 51.6 bits (122), Expect = 6e-06 Identities = 25/103 (24%), Positives = 54/103 (52%), Gaps = 1/103 (0%) Query: 1398 EDEEEDQEEEEQEEEDDDEDDDDTDDLDELDTDQLLEAELEEDDNNENAGEDGDNDFSPS 1457 +D+ +D + + +D D DD +DD + D D ++E +D ++++ D +D S + Sbjct: 216 DDKSDDSDVPDDSSDDSDVPDDSSDDSEAPD-DSSDDSEAPDDSSDDSEAPDDSSDDSEA 274 Query: 1458 DEELANLLEEGEDGEDEDSDADEEVELILGDTDSSDNSDLEDD 1500 ++ ++ E +D D+ +D+ + D SD+SD+ +D Sbjct: 275 PDDSSDDSEASDDSSDDSEASDDSSDDSEAPDDKSDDSDVPED 317 Score = 51.2 bits (121), Expect = 7e-06 Identities = 25/104 (24%), Positives = 52/104 (50%) Query: 1397 DEDEEEDQEEEEQEEEDDDEDDDDTDDLDELDTDQLLEAELEEDDNNENAGEDGDNDFSP 1456 D+ E D ++ + DD+ DD D+ D+ D ++++ +D ++++ D +D S Sbjct: 174 DDSEAPDDNSDDSDVPDDNSDDSSDDNSDDSSDDNSDDSDVPDDKSDDSDVPDDSSDDSD 233 Query: 1457 SDEELANLLEEGEDGEDEDSDADEEVELILGDTDSSDNSDLEDD 1500 ++ ++ E +D D+ D+ + DSSD+S+ DD Sbjct: 234 VPDDSSDDSEAPDDSSDDSEAPDDSSDDSEAPDDSSDDSEAPDD 277 Score = 48.5 bits (114), Expect = 5e-05 Identities = 27/104 (25%), Positives = 51/104 (49%), Gaps = 7/104 (6%) Query: 1398 EDEEEDQEEEEQEEEDDDEDDDDTDDLDELDTDQLLEAELEEDDNNENAGEDGD-NDFSP 1456 +D +D E + +D D DD++DD + ++D + ++ D ++ +D D D S Sbjct: 170 DDNSDDSEAPDDNSDDSDVPDDNSDDSSDDNSDDSSDDNSDDSDVPDDKSDDSDVPDDSS 229 Query: 1457 SDEELANLLEEGEDGEDEDSDADEEVELILGDTDSSDNSDLEDD 1500 D ++ + + + D+ SD E + DSSD+S+ DD Sbjct: 230 DDSDVPDDSSDDSEAPDDSSDDSEAPD------DSSDDSEAPDD 267 Score = 48.1 bits (113), Expect = 6e-05 Identities = 26/112 (23%), Positives = 54/112 (48%), Gaps = 6/112 (5%) Query: 1395 AEDEDEEEDQEEEEQEEEDDDEDD------DDTDDLDELDTDQLLEAELEEDDNNENAGE 1448 +E D+ D + + DD DD DD D ++ D+ ++++ +D ++++ Sbjct: 176 SEAPDDNSDDSDVPDDNSDDSSDDNSDDSSDDNSDDSDVPDDKSDDSDVPDDSSDDSDVP 235 Query: 1449 DGDNDFSPSDEELANLLEEGEDGEDEDSDADEEVELILGDTDSSDNSDLEDD 1500 D +D S + ++ ++ E +D D+ D+ + DSSD+S+ DD Sbjct: 236 DDSSDDSEAPDDSSDDSEAPDDSSDDSEAPDDSSDDSEAPDDSSDDSEASDD 287 Score = 45.4 bits (106), Expect = 4e-04 Identities = 27/105 (25%), Positives = 49/105 (46%), Gaps = 2/105 (1%) Query: 1395 AEDEDEEEDQEEEEQEEEDDDEDDDDTDDLDELDTDQLLEAELEEDDNNENAGEDGDNDF 1454 +E D+ D E + DD E DD+ D E D+ ++++ ED ++++ D ++D Sbjct: 272 SEAPDDSSDDSEASDDSSDDSEASDDSSDDSEAPDDKSDDSDVPEDKSDDSDVPDDNSDD 331 Query: 1455 SPSDEELANLLEEGEDGEDEDSDADEEVELILGDTDSSDNSDLED 1499 +L EG+ DE+ E + DSSD++ +D Sbjct: 332 LEVPVPAEDLCNEGQIASDEEELV--EAAAAVSQHDSSDDAGEQD 374 Score = 44.7 bits (104), Expect = 7e-04 Identities = 25/106 (23%), Positives = 53/106 (50%), Gaps = 11/106 (10%) Query: 1395 AEDEDEEEDQEEEEQEEEDDDEDDDDTDDLDELDTDQLLEAELEEDDNNENAGEDGDNDF 1454 ++D + +D ++ + +D+ +D D DD + +D DD++++ +D D Sbjct: 163 SDDSEAPDDNSDDSEAPDDNSDDSDVPDDNSDDSSDD------NSDDSSDDNSDDSDVPD 216 Query: 1455 SPSDEELANLLEEGEDGEDEDSDADEEVELILGDTDSSDNSDLEDD 1500 SD+ +++ ++ D D D+ ++ E DSSD+S+ DD Sbjct: 217 DKSDD--SDVPDDSSDDSDVPDDSSDDSE---APDDSSDDSEAPDD 257 Score = 43.1 bits (100), Expect = 0.002 Identities = 34/129 (26%), Positives = 56/129 (43%), Gaps = 30/129 (23%) Query: 1381 DTVCRLYEVGRQRLAEDEDEEEDQE---------EEEQEEEDDDEDDDDTDDLDELDTDQ 1431 D C +E + +L E ++E E E DDD DDD+ +DL+ D Sbjct: 84 DEECHTHEEKKAKLLEINSDDESPECCHVKPAIQEPPIVISDDDNDDDNGNDLEVPD--- 140 Query: 1432 LLEAELEEDDNNENAGEDGDNDFSPSDEELANLLEEGEDGEDEDSDADEEVELILGDTDS 1491 + D++E ++ D+ +P D + E D +DS+A + D+ Sbjct: 141 ------DNSDDSEAPDDNSDDSEAPDDNSDDS---EAPDDNSDDSEAPD---------DN 182 Query: 1492 SDNSDLEDD 1500 SD+SD+ DD Sbjct: 183 SDDSDVPDD 191 >gi|42740903 MTERF domain containing 2 [Homo sapiens] Length = 381 Score = 53.1 bits (126), Expect = 2e-06 Identities = 26/75 (34%), Positives = 44/75 (58%), Gaps = 7/75 (9%) Query: 1387 YEVGRQRLAEDEDEEEDQEEEEQEEE-DDDEDDDDTDDLDELDTDQLLEAELEEDDNNEN 1445 ++V ++ LA +E+E E +++ D+DEDDDD +D DE D D+ ++DD +++ Sbjct: 313 FQVFKKLLAREEEESESSTSDDKRASLDEDEDDDDEEDNDEDDNDE------DDDDEDDD 366 Query: 1446 AGEDGDNDFSPSDEE 1460 ED D D +EE Sbjct: 367 EAEDNDEDEDDDEEE 381 Score = 42.0 bits (97), Expect = 0.004 Identities = 27/74 (36%), Positives = 36/74 (48%), Gaps = 16/74 (21%) Query: 1408 EQEEEDDDEDDDDTDDLDELDTDQLLEAELEEDDNNENAGEDGDNDFSPSDEELANLLEE 1467 E+EE + DD LDE +EDD++E ++ DND DE+ +E Sbjct: 323 EEEESESSTSDDKRASLDE-----------DEDDDDEEDNDEDDNDEDDDDED----DDE 367 Query: 1468 GEDGEDEDSDADEE 1481 ED DED D DEE Sbjct: 368 AED-NDEDEDDDEE 380 Score = 38.5 bits (88), Expect = 0.050 Identities = 19/55 (34%), Positives = 35/55 (63%), Gaps = 4/55 (7%) Query: 1446 AGEDGDNDFSPSDEELANLLEEGEDGEDEDSDADEEVELILGDTDSSDNSDLEDD 1500 A E+ +++ S SD++ A+L E+ +D ++ED+D D+ E D D D+ + ED+ Sbjct: 321 AREEEESESSTSDDKRASLDEDEDDDDEEDNDEDDNDE----DDDDEDDDEAEDN 371 Score = 33.1 bits (74), Expect = 2.1 Identities = 21/70 (30%), Positives = 34/70 (48%), Gaps = 10/70 (14%) Query: 1431 QLLEAELEEDDNNENAGEDGDNDFSPSDEELANLLEEGEDGEDEDSDADEEVELILGDTD 1490 +LL E EE +++ + + D D++ EE D +D D D D+E D + Sbjct: 318 KLLAREEEESESSTSDDKRASLDEDEDDDD-----EEDNDEDDNDEDDDDE-----DDDE 367 Query: 1491 SSDNSDLEDD 1500 + DN + EDD Sbjct: 368 AEDNDEDEDD 377 >gi|86262149 zinc finger and BTB domain containing 7C [Homo sapiens] Length = 619 Score = 53.1 bits (126), Expect = 2e-06 Identities = 28/65 (43%), Positives = 39/65 (60%), Gaps = 3/65 (4%) Query: 1396 EDEDEEEDQEEEEQEEEDDDEDDDDTDDLDELDTDQLL---EAELEEDDNNENAGEDGDN 1452 ED+D+EED+EEEE+EEEDDD+D +D D + L Q + ++ + D E A D Sbjct: 146 EDDDDEEDEEEEEEEEEDDDDDTEDFADQENLPDPQDISCHQSPSKTDHLTEKAYSDTPR 205 Query: 1453 DFSPS 1457 DF S Sbjct: 206 DFPDS 210 Score = 42.7 bits (99), Expect = 0.003 Identities = 22/79 (27%), Positives = 42/79 (53%), Gaps = 4/79 (5%) Query: 1397 DEDEEEDQEEEEQEEEDDDEDDDDTDDLDELDTDQLLEAELEEDDNNENAGEDGDNDFSP 1456 D EE+D+E+++ +E+DDDE+D++ ++ +E D D + E+ + EN + D Sbjct: 132 DGGEEDDKEDDDDDEDDDDEEDEEEEEEEEEDDDD----DTEDFADQENLPDPQDISCHQ 187 Query: 1457 SDEELANLLEEGEDGEDED 1475 S + +L E+ D Sbjct: 188 SPSKTDHLTEKAYSDTPRD 206 Score = 40.0 bits (92), Expect = 0.017 Identities = 18/55 (32%), Positives = 36/55 (65%), Gaps = 2/55 (3%) Query: 1383 VC-RLYEVGRQRLAEDEDEEEDQEEEEQEEEDDDEDDDDTDDLDELDTDQLLEAE 1436 VC + E G ED+ E++D +E++ +EED++E++++ +D D+ DT+ + E Sbjct: 122 VCLEIMEPGGDGGEEDDKEDDDDDEDDDDEEDEEEEEEEEED-DDDDTEDFADQE 175 Score = 32.0 bits (71), Expect = 4.6 Identities = 23/68 (33%), Positives = 32/68 (47%), Gaps = 12/68 (17%) Query: 1440 DDNNENAGEDGDNDFSPSDEELANLLEEGEDGEDEDSDADEEVELILGDTDSSDNSDLED 1499 D E+ ED D+D DEE EE E+ E+ED D D E D +D +L D Sbjct: 132 DGGEEDDKEDDDDDEDDDDEED----EEEEEEEEEDDDDDTE--------DFADQENLPD 179 Query: 1500 DIILSLNE 1507 +S ++ Sbjct: 180 PQDISCHQ 187 >gi|42476169 Paf1, RNA polymerase II associated factor, homolog [Homo sapiens] Length = 531 Score = 53.1 bits (126), Expect = 2e-06 Identities = 31/102 (30%), Positives = 54/102 (52%), Gaps = 4/102 (3%) Query: 1399 DEEEDQEEEEQEEEDDDEDDDDTDDLDELDTDQLLEAELEEDDNNENAGEDGDNDFSPSD 1458 + E +EEEE+E E ++++ +D+ E + E +E +E+ E+GD D SD Sbjct: 372 ENHEPEEEEEEEMETEEKEAGGSDEEQEKGSSSEKEGSEDEHSGSESEREEGDRD-EASD 430 Query: 1459 EELANLLEEGEDGEDEDSDADEEVELILGDTDSSDNSDLEDD 1500 + + E E EDE A ++ E+ D DS D++D +D+ Sbjct: 431 KSGSG---EDESSEDEARAARDKEEIFGSDADSEDDADSDDE 469 Score = 33.9 bits (76), Expect = 1.2 Identities = 27/88 (30%), Positives = 38/88 (43%), Gaps = 11/88 (12%) Query: 1395 AEDEDEEEDQEEEEQEEEDDDED---DDDTDDLDELDTDQLLEAELEEDDNNENAGEDGD 1451 +E E E++ E E E+ D D D DE D+ A D E G D D Sbjct: 404 SEKEGSEDEHSGSESEREEGDRDEASDKSGSGEDESSEDEARAAR----DKEEIFGSDAD 459 Query: 1452 N-DFSPSDEELANLLEEGEDGEDEDSDA 1478 + D + SD+E + + G D DSD+ Sbjct: 460 SEDDADSDDEDRG---QAQGGSDNDSDS 484 Score = 33.5 bits (75), Expect = 1.6 Identities = 24/94 (25%), Positives = 36/94 (38%), Gaps = 8/94 (8%) Query: 1396 EDEDEEEDQEEEEQEEE--DDDEDDDDTDDLDELDTDQLLEAELEEDDNNENAGEDGDND 1453 EDE E++ +EE D D +D D D+ D Q + D+ N G Sbjct: 436 EDESSEDEARAARDKEEIFGSDADSEDDADSDDEDRGQAQGGSDNDSDSGSNGGGQRSRS 495 Query: 1454 FS------PSDEELANLLEEGEDGEDEDSDADEE 1481 S PS E + + E + S+AD + Sbjct: 496 HSRSASPFPSGSEHSAQEDGSEAAASDSSEADSD 529 >gi|195546900 suppressor of Ty 5 homolog isoform a [Homo sapiens] Length = 1087 Score = 52.8 bits (125), Expect = 3e-06 Identities = 31/87 (35%), Positives = 50/87 (57%), Gaps = 5/87 (5%) Query: 1390 GRQRLAEDEDEEEDQEEEEQEEEDDDEDDDDTDDLDELDTDQLLEAELEEDDNNENAGED 1449 G ++ E EDEEE++EEEE +EE+++EDDD L EA+++++ +E+ ED Sbjct: 35 GSEKEEEPEDEEEEEEEEEYDEEEEEEDDDRPPKKPRHGGFILDEADVDDEYEDEDQWED 94 Query: 1450 GDNDFSPSDE-ELANL----LEEGEDG 1471 G D +E E +N+ L+E G Sbjct: 95 GAEDILEKEEIEASNIDNVVLDEDRSG 121 Score = 47.4 bits (111), Expect = 1e-04 Identities = 37/138 (26%), Positives = 61/138 (44%), Gaps = 24/138 (17%) Query: 1388 EVGRQRLAEDEDEEEDQEEEEQEEEDDDEDDDDTDD-------------LDELDTDQLLE 1434 E R +++EE + EEEE+EEE+ DE++++ DD LDE D D E Sbjct: 28 EERRSAAGSEKEEEPEDEEEEEEEEEYDEEEEEEDDDRPPKKPRHGGFILDEADVDDEYE 87 Query: 1435 AELEEDDNNENAGEDGDNDFSPSD-----------EELANLLEEGEDGEDEDSDADEEVE 1483 E + +D E+ E + + S D L NL + + E + + + Sbjct: 88 DEDQWEDGAEDILEKEEIEASNIDNVVLDEDRSGARRLQNLWRDQREEELGEYYMKKYAK 147 Query: 1484 LILGDTDSSDNSDLEDDI 1501 +G+T + +L DDI Sbjct: 148 SSVGETVYGGSDELSDDI 165 Score = 37.0 bits (84), Expect = 0.14 Identities = 29/120 (24%), Positives = 60/120 (50%), Gaps = 20/120 (16%) Query: 1388 EVGRQRLAEDEDEEEDQE-------EEEQEEEDDDEDDDDTDDLDELDTDQLLEAELEED 1440 E +R ++ E+ E D+E E+E+E ED++E++++ ++ DE E EE+ Sbjct: 12 EEDSERSSDGEEAEVDEERRSAAGSEKEEEPEDEEEEEEE-EEYDE---------EEEEE 61 Query: 1441 DNNENAGEDGDNDFSPSDEELANLLEEGEDGEDEDSDADEEVELILGDTDSSDNSDLEDD 1500 D++ + F + ++ + E+ + ED D E+ E+ + + DN L++D Sbjct: 62 DDDRPPKKPRHGGFILDEADVDDEYEDEDQWEDGAEDILEKEEI---EASNIDNVVLDED 118 Score = 36.6 bits (83), Expect = 0.19 Identities = 26/118 (22%), Positives = 53/118 (44%), Gaps = 11/118 (9%) Query: 1394 LAEDEDEEEDQEEEEQEEEDDDEDDDDTDDLDELDTDQLLEAELEEDDNNENA----GED 1449 +++ ED +EE+ + D +E + D + +++ E E EE++ E E+ Sbjct: 1 MSDSEDSNFSEEEDSERSSDGEEAEVDEERRSAAGSEKEEEPEDEEEEEEEEEYDEEEEE 60 Query: 1450 GDNDFSPSDEELANLLEEGEDGEDEDSDADEEVELILGDTDSSDNSDLE----DDIIL 1503 D+D P + + D +DE D D+ + G D + ++E D+++L Sbjct: 61 EDDDRPPKKPRHGGFILDEADVDDEYEDEDQWED---GAEDILEKEEIEASNIDNVVL 115 >gi|161169023 suppressor of Ty 5 homolog isoform a [Homo sapiens] Length = 1087 Score = 52.8 bits (125), Expect = 3e-06 Identities = 31/87 (35%), Positives = 50/87 (57%), Gaps = 5/87 (5%) Query: 1390 GRQRLAEDEDEEEDQEEEEQEEEDDDEDDDDTDDLDELDTDQLLEAELEEDDNNENAGED 1449 G ++ E EDEEE++EEEE +EE+++EDDD L EA+++++ +E+ ED Sbjct: 35 GSEKEEEPEDEEEEEEEEEYDEEEEEEDDDRPPKKPRHGGFILDEADVDDEYEDEDQWED 94 Query: 1450 GDNDFSPSDE-ELANL----LEEGEDG 1471 G D +E E +N+ L+E G Sbjct: 95 GAEDILEKEEIEASNIDNVVLDEDRSG 121 Score = 47.4 bits (111), Expect = 1e-04 Identities = 37/138 (26%), Positives = 61/138 (44%), Gaps = 24/138 (17%) Query: 1388 EVGRQRLAEDEDEEEDQEEEEQEEEDDDEDDDDTDD-------------LDELDTDQLLE 1434 E R +++EE + EEEE+EEE+ DE++++ DD LDE D D E Sbjct: 28 EERRSAAGSEKEEEPEDEEEEEEEEEYDEEEEEEDDDRPPKKPRHGGFILDEADVDDEYE 87 Query: 1435 AELEEDDNNENAGEDGDNDFSPSD-----------EELANLLEEGEDGEDEDSDADEEVE 1483 E + +D E+ E + + S D L NL + + E + + + Sbjct: 88 DEDQWEDGAEDILEKEEIEASNIDNVVLDEDRSGARRLQNLWRDQREEELGEYYMKKYAK 147 Query: 1484 LILGDTDSSDNSDLEDDI 1501 +G+T + +L DDI Sbjct: 148 SSVGETVYGGSDELSDDI 165 Score = 37.0 bits (84), Expect = 0.14 Identities = 29/120 (24%), Positives = 60/120 (50%), Gaps = 20/120 (16%) Query: 1388 EVGRQRLAEDEDEEEDQE-------EEEQEEEDDDEDDDDTDDLDELDTDQLLEAELEED 1440 E +R ++ E+ E D+E E+E+E ED++E++++ ++ DE E EE+ Sbjct: 12 EEDSERSSDGEEAEVDEERRSAAGSEKEEEPEDEEEEEEE-EEYDE---------EEEEE 61 Query: 1441 DNNENAGEDGDNDFSPSDEELANLLEEGEDGEDEDSDADEEVELILGDTDSSDNSDLEDD 1500 D++ + F + ++ + E+ + ED D E+ E+ + + DN L++D Sbjct: 62 DDDRPPKKPRHGGFILDEADVDDEYEDEDQWEDGAEDILEKEEI---EASNIDNVVLDED 118 Score = 36.6 bits (83), Expect = 0.19 Identities = 26/118 (22%), Positives = 53/118 (44%), Gaps = 11/118 (9%) Query: 1394 LAEDEDEEEDQEEEEQEEEDDDEDDDDTDDLDELDTDQLLEAELEEDDNNENA----GED 1449 +++ ED +EE+ + D +E + D + +++ E E EE++ E E+ Sbjct: 1 MSDSEDSNFSEEEDSERSSDGEEAEVDEERRSAAGSEKEEEPEDEEEEEEEEEYDEEEEE 60 Query: 1450 GDNDFSPSDEELANLLEEGEDGEDEDSDADEEVELILGDTDSSDNSDLE----DDIIL 1503 D+D P + + D +DE D D+ + G D + ++E D+++L Sbjct: 61 EDDDRPPKKPRHGGFILDEADVDDEYEDEDQWED---GAEDILEKEEIEASNIDNVVL 115 >gi|20149524 suppressor of Ty 5 homolog isoform a [Homo sapiens] Length = 1087 Score = 52.8 bits (125), Expect = 3e-06 Identities = 31/87 (35%), Positives = 50/87 (57%), Gaps = 5/87 (5%) Query: 1390 GRQRLAEDEDEEEDQEEEEQEEEDDDEDDDDTDDLDELDTDQLLEAELEEDDNNENAGED 1449 G ++ E EDEEE++EEEE +EE+++EDDD L EA+++++ +E+ ED Sbjct: 35 GSEKEEEPEDEEEEEEEEEYDEEEEEEDDDRPPKKPRHGGFILDEADVDDEYEDEDQWED 94 Query: 1450 GDNDFSPSDE-ELANL----LEEGEDG 1471 G D +E E +N+ L+E G Sbjct: 95 GAEDILEKEEIEASNIDNVVLDEDRSG 121 Score = 47.4 bits (111), Expect = 1e-04 Identities = 37/138 (26%), Positives = 61/138 (44%), Gaps = 24/138 (17%) Query: 1388 EVGRQRLAEDEDEEEDQEEEEQEEEDDDEDDDDTDD-------------LDELDTDQLLE 1434 E R +++EE + EEEE+EEE+ DE++++ DD LDE D D E Sbjct: 28 EERRSAAGSEKEEEPEDEEEEEEEEEYDEEEEEEDDDRPPKKPRHGGFILDEADVDDEYE 87 Query: 1435 AELEEDDNNENAGEDGDNDFSPSD-----------EELANLLEEGEDGEDEDSDADEEVE 1483 E + +D E+ E + + S D L NL + + E + + + Sbjct: 88 DEDQWEDGAEDILEKEEIEASNIDNVVLDEDRSGARRLQNLWRDQREEELGEYYMKKYAK 147 Query: 1484 LILGDTDSSDNSDLEDDI 1501 +G+T + +L DDI Sbjct: 148 SSVGETVYGGSDELSDDI 165 Score = 37.0 bits (84), Expect = 0.14 Identities = 29/120 (24%), Positives = 60/120 (50%), Gaps = 20/120 (16%) Query: 1388 EVGRQRLAEDEDEEEDQE-------EEEQEEEDDDEDDDDTDDLDELDTDQLLEAELEED 1440 E +R ++ E+ E D+E E+E+E ED++E++++ ++ DE E EE+ Sbjct: 12 EEDSERSSDGEEAEVDEERRSAAGSEKEEEPEDEEEEEEE-EEYDE---------EEEEE 61 Query: 1441 DNNENAGEDGDNDFSPSDEELANLLEEGEDGEDEDSDADEEVELILGDTDSSDNSDLEDD 1500 D++ + F + ++ + E+ + ED D E+ E+ + + DN L++D Sbjct: 62 DDDRPPKKPRHGGFILDEADVDDEYEDEDQWEDGAEDILEKEEI---EASNIDNVVLDED 118 Score = 36.6 bits (83), Expect = 0.19 Identities = 26/118 (22%), Positives = 53/118 (44%), Gaps = 11/118 (9%) Query: 1394 LAEDEDEEEDQEEEEQEEEDDDEDDDDTDDLDELDTDQLLEAELEEDDNNENA----GED 1449 +++ ED +EE+ + D +E + D + +++ E E EE++ E E+ Sbjct: 1 MSDSEDSNFSEEEDSERSSDGEEAEVDEERRSAAGSEKEEEPEDEEEEEEEEEYDEEEEE 60 Query: 1450 GDNDFSPSDEELANLLEEGEDGEDEDSDADEEVELILGDTDSSDNSDLE----DDIIL 1503 D+D P + + D +DE D D+ + G D + ++E D+++L Sbjct: 61 EDDDRPPKKPRHGGFILDEADVDDEYEDEDQWED---GAEDILEKEEIEASNIDNVVL 115 >gi|210147569 acidic (leucine-rich) nuclear phosphoprotein 32 family, member E isoform 2 [Homo sapiens] Length = 227 Score = 52.8 bits (125), Expect = 3e-06 Identities = 35/120 (29%), Positives = 64/120 (53%), Gaps = 16/120 (13%) Query: 1397 DEDEEEDQEEEEQEEEDDDEDDDDTDDLDELDTDQLLEAELEEDDNNENAGEDGD---ND 1453 D+++ E + EE+++ED DEDD++ ++ + + E E EE++ +E+ ED D ++ Sbjct: 108 DQEDNEAPDSEEEDDEDGDEDDEEEEENEAGPPEGYEEEEEEEEEEDEDEDEDEDEAGSE 167 Query: 1454 FSPSDEELA---NLLEEGEDGEDED---SDADEEVELILG-------DTDSSDNSDLEDD 1500 +EE+ + EE +D ED+D + +EE E G D+ D+ + EDD Sbjct: 168 LGEGEEEVGLSYLMKEEIQDEEDDDDYVEEGEEEEEEEEGGLRGEKRKRDAEDDGEEEDD 227 Score = 50.1 bits (118), Expect = 2e-05 Identities = 25/94 (26%), Positives = 57/94 (60%), Gaps = 9/94 (9%) Query: 1388 EVGRQRLAEDEDEEEDQEEEEQEEEDDDEDDDDTDDLDELDTDQLLEAELEEDDNNENAG 1447 E G E+E+EEE++E+E+++E++D+ + + +E+ L++ E+++++++++ Sbjct: 136 EAGPPEGYEEEEEEEEEEDEDEDEDEDEAGSELGEGEEEVGLSYLMKEEIQDEEDDDDYV 195 Query: 1448 EDGDNDFSPSDEELANLLEE------GEDGEDED 1475 E+G+ + +EE L E +DGE+ED Sbjct: 196 EEGEEE---EEEEEGGLRGEKRKRDAEDDGEEED 226 Score = 34.3 bits (77), Expect = 0.93 Identities = 34/142 (23%), Positives = 61/142 (42%), Gaps = 40/142 (28%) Query: 1369 IENQGSMDALNMDTVC------RLYEVGRQRLAEDEDEEEDQEEEEQEEEDDDEDDDDTD 1422 ++N S+D N + ++E+ +Q D ++ED E + EEEDD++ D+D Sbjct: 71 LKNLKSLDLFNCEITNLEDYRESIFELLQQITYLDGFDQEDNEAPDSEEEDDEDGDEDD- 129 Query: 1423 DLDELDTDQLLEAELEEDDNNENAGEDGDNDFSPSDEELANLLEEGEDGEDEDSDADEEV 1482 EE++ NE AG EG + E+E+ + ++E Sbjct: 130 ---------------EEEEENE-AGPP-----------------EGYEEEEEEEEEEDED 156 Query: 1483 ELILGDTDSSDNSDLEDDIILS 1504 E D S+ + E+++ LS Sbjct: 157 EDEDEDEAGSELGEGEEEVGLS 178 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.318 0.134 0.393 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 59,385,173 Number of Sequences: 37866 Number of extensions: 2994723 Number of successful extensions: 49524 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 549 Number of HSP's successfully gapped in prelim test: 373 Number of HSP's that attempted gapping in prelim test: 24247 Number of HSP's gapped (non-prelim): 11011 length of query: 1507 length of database: 18,247,518 effective HSP length: 115 effective length of query: 1392 effective length of database: 13,892,928 effective search space: 19338955776 effective search space used: 19338955776 T: 11 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits) S2: 69 (31.2 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.