Guide to the Human Genome
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Search of human proteins with 7662316

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|7662316 HIV-1 Vpr binding protein [Homo sapiens]
         (1507 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|7662316 HIV-1 Vpr binding protein [Homo sapiens]                  3024   0.0  
gi|55956788 nucleolin [Homo sapiens]                                   68   8e-11
gi|5454088 acidic (leucine-rich) nuclear phosphoprotein 32 famil...    62   3e-09
gi|60498973 myelin transcription factor 1-like [Homo sapiens]          62   3e-09
gi|210032580 SET domain containing 1B [Homo sapiens]                   62   3e-09
gi|21735415 centromere protein B [Homo sapiens]                        61   7e-09
gi|115529449 upstream binding transcription factor, RNA polymera...    61   7e-09
gi|115529451 upstream binding transcription factor, RNA polymera...    61   7e-09
gi|7657671 upstream binding transcription factor, RNA polymerase...    61   7e-09
gi|239756368 PREDICTED: similar to acidic (leucine-rich) nuclear...    61   9e-09
gi|239750893 PREDICTED: similar to acidic (leucine-rich) nuclear...    61   9e-09
gi|214010181 amyloid beta (A4) precursor-like protein 2 isoform ...    60   2e-08
gi|4502147 amyloid beta (A4) precursor-like protein 2 isoform 1 ...    60   2e-08
gi|214010183 amyloid beta (A4) precursor-like protein 2 isoform ...    60   2e-08
gi|61676188 HECT, UBA and WWE domain containing 1 [Homo sapiens]       59   5e-08
gi|155030232 proline, glutamic acid and leucine rich protein 1 [...    58   8e-08
gi|4503257 death-domain associated protein isoform a [Homo sapiens]    55   4e-07
gi|215422388 death-domain associated protein isoform a [Homo sap...    55   4e-07
gi|215422366 death-domain associated protein isoform b [Homo sap...    55   4e-07
gi|17975763 myelin transcription factor 1 [Homo sapiens]               55   4e-07
gi|195546902 suppressor of Ty 5 homolog isoform b [Homo sapiens]       55   7e-07
gi|114155142 nuclear pore complex-associated protein TPR [Homo s...    54   9e-07
gi|16445033 ACRC protein [Homo sapiens]                                54   1e-06
gi|42740903 MTERF domain containing 2 [Homo sapiens]                   53   2e-06
gi|86262149 zinc finger and BTB domain containing 7C [Homo sapiens]    53   2e-06
gi|42476169 Paf1, RNA polymerase II associated factor, homolog [...    53   2e-06
gi|195546900 suppressor of Ty 5 homolog isoform a [Homo sapiens]       53   3e-06
gi|161169023 suppressor of Ty 5 homolog isoform a [Homo sapiens]       53   3e-06
gi|20149524 suppressor of Ty 5 homolog isoform a [Homo sapiens]        53   3e-06
gi|210147569 acidic (leucine-rich) nuclear phosphoprotein 32 fam...    53   3e-06

>gi|7662316 HIV-1 Vpr binding protein [Homo sapiens]
          Length = 1507

 Score = 3024 bits (7840), Expect = 0.0
 Identities = 1507/1507 (100%), Positives = 1507/1507 (100%)

Query: 1    MTTVVVHVDSKAELTTLLEQWEKEHGSGQDMVPILTRMSQLIEKETEEYRKGDPDPFDDR 60
            MTTVVVHVDSKAELTTLLEQWEKEHGSGQDMVPILTRMSQLIEKETEEYRKGDPDPFDDR
Sbjct: 1    MTTVVVHVDSKAELTTLLEQWEKEHGSGQDMVPILTRMSQLIEKETEEYRKGDPDPFDDR 60

Query: 61   HPGRADPECMLGHLLRILFKNDDFMNALVNAYVMTSREPPLNTAACRLLLDIMPGLETAV 120
            HPGRADPECMLGHLLRILFKNDDFMNALVNAYVMTSREPPLNTAACRLLLDIMPGLETAV
Sbjct: 61   HPGRADPECMLGHLLRILFKNDDFMNALVNAYVMTSREPPLNTAACRLLLDIMPGLETAV 120

Query: 121  VFQEKEGIVENLFKWAREADQPLRTYSTGLLGGAMENQDIAANYRDENSQLVAIVLRRLR 180
            VFQEKEGIVENLFKWAREADQPLRTYSTGLLGGAMENQDIAANYRDENSQLVAIVLRRLR
Sbjct: 121  VFQEKEGIVENLFKWAREADQPLRTYSTGLLGGAMENQDIAANYRDENSQLVAIVLRRLR 180

Query: 181  ELQLQEVALRQENKRPSPRKLSSEPLLPLDEEAVDMDYGDMAVDVVDGDQEEASGDMEIS 240
            ELQLQEVALRQENKRPSPRKLSSEPLLPLDEEAVDMDYGDMAVDVVDGDQEEASGDMEIS
Sbjct: 181  ELQLQEVALRQENKRPSPRKLSSEPLLPLDEEAVDMDYGDMAVDVVDGDQEEASGDMEIS 240

Query: 241  FHLDSGHKTSSRVNSTTKPEDGGLKKNKSAKQGDRENFRKAKQKLGFSSSDPDRMFVELS 300
            FHLDSGHKTSSRVNSTTKPEDGGLKKNKSAKQGDRENFRKAKQKLGFSSSDPDRMFVELS
Sbjct: 241  FHLDSGHKTSSRVNSTTKPEDGGLKKNKSAKQGDRENFRKAKQKLGFSSSDPDRMFVELS 300

Query: 301  NSSWSEMSPWVIGTNYTLYPMTPAIEQRLILQYLTPLGEYQELLPIFMQLGSRELMMFYI 360
            NSSWSEMSPWVIGTNYTLYPMTPAIEQRLILQYLTPLGEYQELLPIFMQLGSRELMMFYI
Sbjct: 301  NSSWSEMSPWVIGTNYTLYPMTPAIEQRLILQYLTPLGEYQELLPIFMQLGSRELMMFYI 360

Query: 361  DLKQTNDVLLTFEALKHLASLLLHNKFATEFVAHGGVQKLLEIPRPSMAATGVSMCLYYL 420
            DLKQTNDVLLTFEALKHLASLLLHNKFATEFVAHGGVQKLLEIPRPSMAATGVSMCLYYL
Sbjct: 361  DLKQTNDVLLTFEALKHLASLLLHNKFATEFVAHGGVQKLLEIPRPSMAATGVSMCLYYL 420

Query: 421  SYNQDAMERVCMHPHNVLSDVVNYTLWLMECSHASGCCHATMFFSICFSFRAVLELFDRY 480
            SYNQDAMERVCMHPHNVLSDVVNYTLWLMECSHASGCCHATMFFSICFSFRAVLELFDRY
Sbjct: 421  SYNQDAMERVCMHPHNVLSDVVNYTLWLMECSHASGCCHATMFFSICFSFRAVLELFDRY 480

Query: 481  DGLRRLVNLISTLEILNLEDQGALLSDDEIFASRQTGKHTCMALRKYFEAHLAIKLEQVK 540
            DGLRRLVNLISTLEILNLEDQGALLSDDEIFASRQTGKHTCMALRKYFEAHLAIKLEQVK
Sbjct: 481  DGLRRLVNLISTLEILNLEDQGALLSDDEIFASRQTGKHTCMALRKYFEAHLAIKLEQVK 540

Query: 541  QSLQRTEGGILVHPQPPYKACSYTHEQIVEMMEFLIEYGPAQLYWEPAEVFLKLSCVQLL 600
            QSLQRTEGGILVHPQPPYKACSYTHEQIVEMMEFLIEYGPAQLYWEPAEVFLKLSCVQLL
Sbjct: 541  QSLQRTEGGILVHPQPPYKACSYTHEQIVEMMEFLIEYGPAQLYWEPAEVFLKLSCVQLL 600

Query: 601  LQLISIACNWKTYYARNDTVRFALDVLAILTVVPKIQLQLAESVDVLDEAGSTVSTVGIS 660
            LQLISIACNWKTYYARNDTVRFALDVLAILTVVPKIQLQLAESVDVLDEAGSTVSTVGIS
Sbjct: 601  LQLISIACNWKTYYARNDTVRFALDVLAILTVVPKIQLQLAESVDVLDEAGSTVSTVGIS 660

Query: 661  IILGVAEGEFFIHDAEIQKSALQIIINCVCGPDNRISSIGKFISGTPRRKLPQNPKSSEH 720
            IILGVAEGEFFIHDAEIQKSALQIIINCVCGPDNRISSIGKFISGTPRRKLPQNPKSSEH
Sbjct: 661  IILGVAEGEFFIHDAEIQKSALQIIINCVCGPDNRISSIGKFISGTPRRKLPQNPKSSEH 720

Query: 721  TLAKMWNVVQSNNGIKVLLSLLSIKMPITDADQIRALACKALVGLSRSSTVRQIISKLPL 780
            TLAKMWNVVQSNNGIKVLLSLLSIKMPITDADQIRALACKALVGLSRSSTVRQIISKLPL
Sbjct: 721  TLAKMWNVVQSNNGIKVLLSLLSIKMPITDADQIRALACKALVGLSRSSTVRQIISKLPL 780

Query: 781  FSSCQIQQLMKEPVLQDKRSDHVKFCKYAAELIERVSGKPLLIGTDVSLARLQKADVVAQ 840
            FSSCQIQQLMKEPVLQDKRSDHVKFCKYAAELIERVSGKPLLIGTDVSLARLQKADVVAQ
Sbjct: 781  FSSCQIQQLMKEPVLQDKRSDHVKFCKYAAELIERVSGKPLLIGTDVSLARLQKADVVAQ 840

Query: 841  SRISFPEKELLLLIRNHLISKGLGETATVLTKEADLPMTAASHSSAFTPVTAAASPVSLP 900
            SRISFPEKELLLLIRNHLISKGLGETATVLTKEADLPMTAASHSSAFTPVTAAASPVSLP
Sbjct: 841  SRISFPEKELLLLIRNHLISKGLGETATVLTKEADLPMTAASHSSAFTPVTAAASPVSLP 900

Query: 901  RTPRIANGIATRLGSHAAVGASAPSAPTAHPQPRPPQGPLALPGPSYAGNSPLIGRISFI 960
            RTPRIANGIATRLGSHAAVGASAPSAPTAHPQPRPPQGPLALPGPSYAGNSPLIGRISFI
Sbjct: 901  RTPRIANGIATRLGSHAAVGASAPSAPTAHPQPRPPQGPLALPGPSYAGNSPLIGRISFI 960

Query: 961  RERPSPCNGRKIRVLRQKSDHGAYSQSPAIKKQLDRHLPSPPTLDSIITEYLREQHARCK 1020
            RERPSPCNGRKIRVLRQKSDHGAYSQSPAIKKQLDRHLPSPPTLDSIITEYLREQHARCK
Sbjct: 961  RERPSPCNGRKIRVLRQKSDHGAYSQSPAIKKQLDRHLPSPPTLDSIITEYLREQHARCK 1020

Query: 1021 NPVATCPPFSLFTPHQCPEPKQRRQAPINFTSRLNRRASFPKYGGVDGGCFDRHLIFSRF 1080
            NPVATCPPFSLFTPHQCPEPKQRRQAPINFTSRLNRRASFPKYGGVDGGCFDRHLIFSRF
Sbjct: 1021 NPVATCPPFSLFTPHQCPEPKQRRQAPINFTSRLNRRASFPKYGGVDGGCFDRHLIFSRF 1080

Query: 1081 RPISVFREANEDESGFTCCAFSARERFLMLGTCTGQLKLYNVFSGQEEASYNCHNSAITH 1140
            RPISVFREANEDESGFTCCAFSARERFLMLGTCTGQLKLYNVFSGQEEASYNCHNSAITH
Sbjct: 1081 RPISVFREANEDESGFTCCAFSARERFLMLGTCTGQLKLYNVFSGQEEASYNCHNSAITH 1140

Query: 1141 LEPSRDGSLLLTSATWSQPLSALWGMKSVFDMKHSFTEDHYVEFSKHSQDRVIGTKGDIA 1200
            LEPSRDGSLLLTSATWSQPLSALWGMKSVFDMKHSFTEDHYVEFSKHSQDRVIGTKGDIA
Sbjct: 1141 LEPSRDGSLLLTSATWSQPLSALWGMKSVFDMKHSFTEDHYVEFSKHSQDRVIGTKGDIA 1200

Query: 1201 HIYDIQTGNKLLTLFNPDLANNYKRNCATFNPTDDLVLNDGVLWDVRSAQAIHKFDKFNM 1260
            HIYDIQTGNKLLTLFNPDLANNYKRNCATFNPTDDLVLNDGVLWDVRSAQAIHKFDKFNM
Sbjct: 1201 HIYDIQTGNKLLTLFNPDLANNYKRNCATFNPTDDLVLNDGVLWDVRSAQAIHKFDKFNM 1260

Query: 1261 NISGVFHPNGLEVIINTEIWDLRTFHLLHTVPALDQCRVVFNHTGTVMYGAMLQADDEDD 1320
            NISGVFHPNGLEVIINTEIWDLRTFHLLHTVPALDQCRVVFNHTGTVMYGAMLQADDEDD
Sbjct: 1261 NISGVFHPNGLEVIINTEIWDLRTFHLLHTVPALDQCRVVFNHTGTVMYGAMLQADDEDD 1320

Query: 1321 LMEERMKSPFGSSFRTFNATDYKPIATIDVKRNIFDLCTDTKDCYLAVIENQGSMDALNM 1380
            LMEERMKSPFGSSFRTFNATDYKPIATIDVKRNIFDLCTDTKDCYLAVIENQGSMDALNM
Sbjct: 1321 LMEERMKSPFGSSFRTFNATDYKPIATIDVKRNIFDLCTDTKDCYLAVIENQGSMDALNM 1380

Query: 1381 DTVCRLYEVGRQRLAEDEDEEEDQEEEEQEEEDDDEDDDDTDDLDELDTDQLLEAELEED 1440
            DTVCRLYEVGRQRLAEDEDEEEDQEEEEQEEEDDDEDDDDTDDLDELDTDQLLEAELEED
Sbjct: 1381 DTVCRLYEVGRQRLAEDEDEEEDQEEEEQEEEDDDEDDDDTDDLDELDTDQLLEAELEED 1440

Query: 1441 DNNENAGEDGDNDFSPSDEELANLLEEGEDGEDEDSDADEEVELILGDTDSSDNSDLEDD 1500
            DNNENAGEDGDNDFSPSDEELANLLEEGEDGEDEDSDADEEVELILGDTDSSDNSDLEDD
Sbjct: 1441 DNNENAGEDGDNDFSPSDEELANLLEEGEDGEDEDSDADEEVELILGDTDSSDNSDLEDD 1500

Query: 1501 IILSLNE 1507
            IILSLNE
Sbjct: 1501 IILSLNE 1507


>gi|55956788 nucleolin [Homo sapiens]
          Length = 710

 Score = 67.8 bits (164), Expect = 8e-11
 Identities = 42/136 (30%), Positives = 64/136 (47%), Gaps = 30/136 (22%)

Query: 1390 GRQRLAEDEDEEEDQEEEEQEEEDDDEDDDDTDDLDELDTDQLLEAELEEDDNNENAGED 1449
            G+    ED DEEED + EE EE+D+DED+D+ D+++         A   ED+++E+  +D
Sbjct: 137  GKNAKKEDSDEEEDDDSEEDEEDDEDEDEDE-DEIEPAAMKAAAAAPASEDEDDEDDEDD 195

Query: 1450 GDNDFSPSDEELANLLE-------------------------EGEDGEDEDSDADEEVEL 1484
             D+D    D+     +E                         E ED EDED D DE+ E 
Sbjct: 196  EDDDDDEEDDSEEEAMETTPAKGKKAAKVVPVKAKNVAEDEDEEEDDEDEDDDDDEDDE- 254

Query: 1485 ILGDTDSSDNSDLEDD 1500
               D D  D+ + E++
Sbjct: 255  ---DDDDEDDEEEEEE 267



 Score = 56.6 bits (135), Expect = 2e-07
 Identities = 36/118 (30%), Positives = 57/118 (48%), Gaps = 37/118 (31%)

Query: 1396 EDEDEEEDQEEEE------------QEEEDDDEDDDDTDDLDELDTDQLLEA-------- 1435
            +DEDE+ED++E E             E+EDD++D+DD DD D+ + D   EA        
Sbjct: 159  DDEDEDEDEDEIEPAAMKAAAAAPASEDEDDEDDEDDEDDDDDEEDDSEEEAMETTPAKG 218

Query: 1436 ------------ELEEDDNNENAGEDGDNDFSPSDEELANLLEEGEDGEDEDSDADEE 1481
                         + ED++ E   ED D+D    DE+     ++ ED E+E+ + +EE
Sbjct: 219  KKAAKVVPVKAKNVAEDEDEEEDDEDEDDDDDEDDED-----DDDEDDEEEEEEEEEE 271



 Score = 56.2 bits (134), Expect = 2e-07
 Identities = 28/64 (43%), Positives = 41/64 (64%), Gaps = 7/64 (10%)

Query: 1385 RLYEVGRQRLAEDEDEEEDQEEEEQEEEDDDEDDDDTDDLDELDTDQLLEAELEEDDNNE 1444
            ++  V  + +AEDEDEEED E+E+ ++++DDEDDDD DD +E       E E EE+   E
Sbjct: 223  KVVPVKAKNVAEDEDEEEDDEDEDDDDDEDDEDDDDEDDEEE-------EEEEEEEPVKE 275

Query: 1445 NAGE 1448
              G+
Sbjct: 276  APGK 279



 Score = 42.0 bits (97), Expect = 0.004
 Identities = 24/80 (30%), Positives = 37/80 (46%), Gaps = 27/80 (33%)

Query: 1396 EDEDEEEDQEEEE---------------------------QEEEDDDEDDDDTDDLDELD 1428
            ED+D++E+ + EE                           ++EE+DDED+DD DD D+ D
Sbjct: 196  EDDDDDEEDDSEEEAMETTPAKGKKAAKVVPVKAKNVAEDEDEEEDDEDEDDDDDEDDED 255

Query: 1429 TDQLLEAELEEDDNNENAGE 1448
             D   + E EE++  E   E
Sbjct: 256  DDDEDDEEEEEEEEEEPVKE 275



 Score = 42.0 bits (97), Expect = 0.004
 Identities = 25/84 (29%), Positives = 40/84 (47%), Gaps = 26/84 (30%)

Query: 1396 EDEDEEEDQEEEEQEE--------------------EDDDEDDDDTDDLDELDTDQLLEA 1435
            +D+DEE+D EEE  E                     ED+DE++DD D+ D+ D D     
Sbjct: 198  DDDDEEDDSEEEAMETTPAKGKKAAKVVPVKAKNVAEDEDEEEDDEDEDDDDDEDD---- 253

Query: 1436 ELEEDDNNENAGEDGDNDFSPSDE 1459
              E+DD+ ++  E+ + +  P  E
Sbjct: 254  --EDDDDEDDEEEEEEEEEEPVKE 275


>gi|5454088 acidic (leucine-rich) nuclear phosphoprotein 32 family,
            member B [Homo sapiens]
          Length = 251

 Score = 62.4 bits (150), Expect = 3e-09
 Identities = 39/90 (43%), Positives = 52/90 (57%), Gaps = 13/90 (14%)

Query: 1395 AEDEDEEEDQ-EEEEQEEEDDDEDDDDTDDLDELDTDQLLEAELEEDDNNENAGEDGDND 1453
            A D D E D  +EEE++EE +DE+D+D +D +E + D       EEDD +E+   D D+D
Sbjct: 155  APDSDAEVDGVDEEEEDEEGEDEEDEDDEDGEEEEFD-------EEDDEDEDVEGDEDDD 207

Query: 1454 FSPSDEELANLLEEGEDGEDEDSDADEEVE 1483
                +EE     E G D EDED D DEE E
Sbjct: 208  EVSEEEE-----EFGLDEEDEDEDEDEEEE 232



 Score = 55.5 bits (132), Expect = 4e-07
 Identities = 34/88 (38%), Positives = 49/88 (55%), Gaps = 11/88 (12%)

Query: 1396 EDEDEEEDQEEEEQEEEDDDEDDDDTDDLDELDTDQLLEAELEEDDNNENAGEDGDNDFS 1455
            E EDEE++ +E+ +EEE D+EDD+D D   + D D++ E E E   + E+  ED D    
Sbjct: 173  EGEDEEDEDDEDGEEEEFDEEDDEDEDVEGDEDDDEVSEEEEEFGLDEEDEDEDED---- 228

Query: 1456 PSDEELANLLEEGEDGEDEDSDADEEVE 1483
              +EE     EEG  GE    + D+E E
Sbjct: 229  --EEE-----EEGGKGEKRKRETDDEGE 249



 Score = 49.3 bits (116), Expect = 3e-05
 Identities = 28/78 (35%), Positives = 48/78 (61%), Gaps = 8/78 (10%)

Query: 1396 EDEDEEEDQEEE--EQEEEDDD-EDDDDTDDLDELDTDQLLEAELEEDDNNENAGEDGDN 1452
            EDED+E+ +EEE  E+++ED+D E D+D D++ E + +  L+ E E++D +E   E G  
Sbjct: 178  EDEDDEDGEEEEFDEEDDEDEDVEGDEDDDEVSEEEEEFGLDEEDEDEDEDEEEEEGGKG 237

Query: 1453 DFSPSDEELANLLEEGED 1470
            +    + +     +EGED
Sbjct: 238  EKRKRETD-----DEGED 250



 Score = 38.5 bits (88), Expect = 0.050
 Identities = 26/71 (36%), Positives = 33/71 (46%), Gaps = 2/71 (2%)

Query: 1437 LEEDDNNENAGEDGDNDFSPSDEELANLLEEGEDGEDEDSDADEEVELILGDTDSSDNSD 1496
            L+  D  +    D D +    DEE  +  EEGED EDED +  EE E    D +  D   
Sbjct: 145  LDGYDREDQEAPDSDAEVDGVDEEEED--EEGEDEEDEDDEDGEEEEFDEEDDEDEDVEG 202

Query: 1497 LEDDIILSLNE 1507
             EDD  +S  E
Sbjct: 203  DEDDDEVSEEE 213



 Score = 34.7 bits (78), Expect = 0.72
 Identities = 17/37 (45%), Positives = 24/37 (64%), Gaps = 4/37 (10%)

Query: 1388 EVGRQRLAEDEDEEEDQEE----EEQEEEDDDEDDDD 1420
            E G     EDEDE+E++EE    E+++ E DDE +DD
Sbjct: 215  EFGLDEEDEDEDEDEEEEEGGKGEKRKRETDDEGEDD 251


>gi|60498973 myelin transcription factor 1-like [Homo sapiens]
          Length = 1184

 Score = 62.4 bits (150), Expect = 3e-09
 Identities = 40/121 (33%), Positives = 69/121 (57%), Gaps = 21/121 (17%)

Query: 1396 EDEDEEEDQEEEEQEEEDDDEDDDDTDDLDELDTDQLLEAELEEDDNNEN---------- 1445
            ++EDEE D+EEEE+ EE+D++DD+D +D+++ + ++  E E EE++ NE+          
Sbjct: 121  DEEDEEGDREEEEEIEEEDEDDDEDGEDVEDEEEEEEEEEEEEEEEENEDHQMNCHNTRI 180

Query: 1446 ----AGEDGDNDFSPSDEELA--NLLEEGEDGEDEDSDADEEVELILGDTDSSDNSDLED 1499
                  +D +ND   + +EL   +LL  G+  ED    A  E E+     +S+ ++ LED
Sbjct: 181  MQDTEKDDNNNDEYDNYDELVAKSLLNLGKIAEDAAYRARTESEM-----NSNTSNSLED 235

Query: 1500 D 1500
            D
Sbjct: 236  D 236



 Score = 62.0 bits (149), Expect = 4e-09
 Identities = 39/105 (37%), Positives = 63/105 (60%), Gaps = 6/105 (5%)

Query: 1396 EDEDEEEDQEEEEQEEEDDDEDDDDTDDLDELDTDQLLEAELEEDDNNENAGEDGDNDFS 1455
            ED DE+E+ E EE  E++D+  D+D +D +E D ++  E E+EE+D +++  EDG+ D  
Sbjct: 97   EDMDEKEEDEGEEYSEDNDEPGDEDEED-EEGDREE--EEEIEEEDEDDD--EDGE-DVE 150

Query: 1456 PSDEELANLLEEGEDGEDEDSDADEEVELILGDTDSSDNSDLEDD 1500
              +EE     EE E+ E+ED   +     I+ DT+  DN++ E D
Sbjct: 151  DEEEEEEEEEEEEEEEENEDHQMNCHNTRIMQDTEKDDNNNDEYD 195



 Score = 47.8 bits (112), Expect = 8e-05
 Identities = 29/118 (24%), Positives = 58/118 (49%), Gaps = 11/118 (9%)

Query: 1389 VGRQRLAEDEDEEEDQEEE-------EQEEEDDDEDDDDTDDLDELDTDQLLEAELEEDD 1441
            + ++R  +D+  +E   +        +    D+ +D D T+D+DE + D   E E   +D
Sbjct: 57   LAKKRKTQDKQPQEPAPKRKPFAVKADSSSVDECDDSDGTEDMDEKEED---EGEEYSED 113

Query: 1442 NNENAGEDGDNDFSPSDEELANLLEEGEDGEDEDSDADEEVELILGDTDSSDNSDLED 1499
            N+E   ED +++    +EE   + EE ED +++  D ++E E    + +  +  + ED
Sbjct: 114  NDEPGDEDEEDEEGDREEE-EEIEEEDEDDDEDGEDVEDEEEEEEEEEEEEEEEENED 170



 Score = 44.3 bits (103), Expect = 0.001
 Identities = 27/108 (25%), Positives = 51/108 (47%), Gaps = 1/108 (0%)

Query: 1394 LAEDEDEEEDQEEEEQEEEDDDEDDDDTDDLDEL-DTDQLLEAELEEDDNNENAGEDGDN 1452
            LA+    ++ Q +E   +        D+  +DE  D+D   + + +E+D  E   ED D 
Sbjct: 57   LAKKRKTQDKQPQEPAPKRKPFAVKADSSSVDECDDSDGTEDMDEKEEDEGEEYSEDNDE 116

Query: 1453 DFSPSDEELANLLEEGEDGEDEDSDADEEVELILGDTDSSDNSDLEDD 1500
                 +E+     EE E+ E+ED D DE+ E +  + +  +  + E++
Sbjct: 117  PGDEDEEDEEGDREEEEEIEEEDEDDDEDGEDVEDEEEEEEEEEEEEE 164



 Score = 36.6 bits (83), Expect = 0.19
 Identities = 30/115 (26%), Positives = 49/115 (42%), Gaps = 25/115 (21%)

Query: 1396 EDEDEEEDQEEE--------EQEEEDDDEDDDDTDDLDELDTDQLLEAELEEDDNNENAG 1447
            E+E+EEE+++ +         Q+ E DD ++D+ D+ DEL    LL        N     
Sbjct: 161  EEEEEEENEDHQMNCHNTRIMQDTEKDDNNNDEYDNYDELVAKSLL--------NLGKIA 212

Query: 1448 EDGDNDFSPSDEELANLLEEGEDGEDEDSDADEEVELILGDTDSSDNSDLEDDII 1502
            ED         E  +N     ED  D++ +   + EL L         DL+ D++
Sbjct: 213  EDAAYRARTESEMNSNTSNSLEDDSDKNENLGRKSELSL---------DLDSDVV 258


>gi|210032580 SET domain containing 1B [Homo sapiens]
          Length = 1923

 Score = 62.4 bits (150), Expect = 3e-09
 Identities = 33/112 (29%), Positives = 58/112 (51%), Gaps = 10/112 (8%)

Query: 1391 RQRLAEDEDEEEDQEEEEQEEEDDDEDDDDTDDLDELDTDQLLEAELEEDDNNENAGEDG 1450
            ++ L+E+++  E++EE E+EEE++D+DDDD+DD D          E E DD +    E  
Sbjct: 1038 KESLSEEQESTEEEEEAEEEEEEEDDDDDDSDDRD----------ESENDDEDTALSEAS 1087

Query: 1451 DNDFSPSDEELANLLEEGEDGEDEDSDADEEVELILGDTDSSDNSDLEDDII 1502
            + D   SDEE    +   +      S++ E  E       S  +S+ E++++
Sbjct: 1088 EKDEGDSDEEETVSIVTSKAEATSSSESSESSEFESSSESSPSSSEDEEEVV 1139



 Score = 52.4 bits (124), Expect = 3e-06
 Identities = 32/129 (24%), Positives = 64/129 (49%), Gaps = 17/129 (13%)

Query: 1389 VGRQRLAEDEDEEEDQEEEEQEEEDDDEDDDDTDDLDELDTDQLLEAELEEDDNNE---- 1444
            +  ++ + +E+EE ++EEEE++++DDD DD D  + D+ DT     +E +E D++E    
Sbjct: 1041 LSEEQESTEEEEEAEEEEEEEDDDDDDSDDRDESENDDEDTALSEASEKDEGDSDEEETV 1100

Query: 1445 -----------NAGEDGDNDFSPSDEELANLLEEGEDGEDEDSDADEEVELILGDTD--S 1491
                       ++     ++F  S E   +  E+ E+    + + +EE E ++ +    S
Sbjct: 1101 SIVTSKAEATSSSESSESSEFESSSESSPSSSEDEEEVVAREEEEEEEEEEMVAEESMAS 1160

Query: 1492 SDNSDLEDD 1500
            +   D E D
Sbjct: 1161 AGPEDFEQD 1169



 Score = 41.2 bits (95), Expect = 0.008
 Identities = 28/140 (20%), Positives = 60/140 (42%), Gaps = 34/140 (24%)

Query: 1390 GRQRLAEDEDEEEDQEEEEQEEEDDD---------------------------------E 1416
            G Q+        ++++EE + E D D                                 E
Sbjct: 976  GDQKRLRPSTSVDEEDEESERERDRDMADTPCELAKRDPKGVGVRRRPARPLELDSGGEE 1035

Query: 1417 DDDDTDDLDELDTDQLLEAELEEDDNNENAGEDGDNDFSPSDEELANLLEEGEDGEDEDS 1476
            D+ ++   ++  T++  EAE EE++ +++  +  D D S +D+E    L E  + ++ DS
Sbjct: 1036 DEKESLSEEQESTEEEEEAEEEEEEEDDDDDDSDDRDESENDDE-DTALSEASEKDEGDS 1094

Query: 1477 DADEEVELILGDTDSSDNSD 1496
            D +E V ++    +++ +S+
Sbjct: 1095 DEEETVSIVTSKAEATSSSE 1114



 Score = 35.8 bits (81), Expect = 0.32
 Identities = 25/115 (21%), Positives = 54/115 (46%), Gaps = 12/115 (10%)

Query: 1403 DQEEEEQEEEDDDEDDDDTDDLDELDTDQL-------LEAELE---EDDNNENAGEDGDN 1452
            D+E+EE E E D +  D   +L + D   +          EL+   E+D  E+  E+ ++
Sbjct: 988  DEEDEESERERDRDMADTPCELAKRDPKGVGVRRRPARPLELDSGGEEDEKESLSEEQES 1047

Query: 1453 --DFSPSDEELANLLEEGEDGEDEDSDADEEVELILGDTDSSDNSDLEDDIILSL 1505
              +   ++EE     ++ +D +D D   +++ +  L +    D  D +++  +S+
Sbjct: 1048 TEEEEEAEEEEEEEDDDDDDSDDRDESENDDEDTALSEASEKDEGDSDEEETVSI 1102


>gi|21735415 centromere protein B [Homo sapiens]
          Length = 599

 Score = 61.2 bits (147), Expect = 7e-09
 Identities = 39/142 (27%), Positives = 69/142 (48%), Gaps = 21/142 (14%)

Query: 1379 NMDTVCRLYEVGRQRLAEDEDEEEDQEEEEQEEEDDDEDDDDTDDLDELDTDQLLEAELE 1438
            N      L   G +   E+E+EEE++ E E+EEE+ +E++++  + +EL  ++ +E E +
Sbjct: 394  NATITTSLKSEGEEEEEEEEEEEEEEGEGEEEEEEGEEEEEEGGEGEELGEEEEVEEEGD 453

Query: 1439 ED-DNNENAGEDGDNDFSPSDEELANLLEEG--------------------EDGEDEDSD 1477
             D D  E   E+  ++   +++    ++E G                    E GED DSD
Sbjct: 454  VDSDEEEEEDEESSSEGLEAEDWAQGVVEAGGSFGAYGAQEEAQCPTLHFLEGGEDSDSD 513

Query: 1478 ADEEVELILGDTDSSDNSDLED 1499
            ++EE +    D D  D+ D ED
Sbjct: 514  SEEEDDEEEDDEDEDDDDDEED 535



 Score = 49.3 bits (116), Expect = 3e-05
 Identities = 38/123 (30%), Positives = 57/123 (46%), Gaps = 32/123 (26%)

Query: 1388 EVGRQRLAEDEDEEEDQE--------EEEQEEEDDDEDDDDTDDLDELDTDQLLEAE--- 1436
            E G     E+E EEE++E        EEE+ EE+ D D D+ ++ DE  + + LEAE   
Sbjct: 418  EEGEGEEEEEEGEEEEEEGGEGEELGEEEEVEEEGDVDSDEEEEEDEESSSEGLEAEDWA 477

Query: 1437 --LEEDDNNENA-----------------GEDGDNDFSPSDEELANLLEEGEDGEDEDSD 1477
              + E   +  A                 GED D+D    D+E  +  +E ED +D++ D
Sbjct: 478  QGVVEAGGSFGAYGAQEEAQCPTLHFLEGGEDSDSDSEEEDDEEED--DEDEDDDDDEED 535

Query: 1478 ADE 1480
             DE
Sbjct: 536  GDE 538



 Score = 45.8 bits (107), Expect = 3e-04
 Identities = 22/76 (28%), Positives = 40/76 (52%)

Query: 1360 DTKDCYLAVIENQGSMDALNMDTVCRLYEVGRQRLAEDEDEEEDQEEEEQEEEDDDEDDD 1419
            + +D    V+E  GS  A       +   +      ED D + ++E++E+E+++D++DDD
Sbjct: 472  EAEDWAQGVVEAGGSFGAYGAQEEAQCPTLHFLEGGEDSDSDSEEEDDEEEDDEDEDDDD 531

Query: 1420 DTDDLDELDTDQLLEA 1435
            D +D DE+      EA
Sbjct: 532  DEEDGDEVPVPSFGEA 547



 Score = 33.9 bits (76), Expect = 1.2
 Identities = 22/60 (36%), Positives = 27/60 (45%), Gaps = 24/60 (40%)

Query: 1398 EDEEEDQEEEEQEEEDDDEDDDDTDDLDELDTDQLLEAELEEDDNNENAGEDGDNDFSPS 1457
            ED + D EEE+ EEEDD+++DDD D                     E   EDGD    PS
Sbjct: 508  EDSDSDSEEEDDEEEDDEDEDDDDD---------------------E---EDGDEVPVPS 543


>gi|115529449 upstream binding transcription factor, RNA polymerase I
            isoform b [Homo sapiens]
          Length = 727

 Score = 61.2 bits (147), Expect = 7e-09
 Identities = 32/101 (31%), Positives = 56/101 (55%), Gaps = 13/101 (12%)

Query: 1395 AEDEDEEEDQEEEEQEEEDDDEDDDDTDDLDELDTDQLLEAELEEDDNNENAGEDGDNDF 1454
            +E++DEE++ +E+E EEE+DDE+ D ++D  +  ++   E E E+ D NE   ED D+D 
Sbjct: 640  SEEDDEEDEDDEDEDEEEEDDENGDSSEDGGD-SSESSSEDESEDGDENEEDDEDEDDD- 697

Query: 1455 SPSDEELANLLEEGEDGEDEDSDADEEVELILGDTDSSDNS 1495
                       E+ ++ ED +S+         GD+  SD++
Sbjct: 698  -----------EDDDEDEDNESEGSSSSSSSSGDSSDSDSN 727



 Score = 57.8 bits (138), Expect = 8e-08
 Identities = 36/97 (37%), Positives = 51/97 (52%), Gaps = 12/97 (12%)

Query: 1405 EEEEQEEEDDDEDDDDTDDLDELDTDQLLEAELEEDDNNENAGED-GDNDFSPSDEELAN 1463
            + + + EEDD+ED+DD D           E E EEDD N ++ ED GD+  S S++E  +
Sbjct: 635  QSKSESEEDDEEDEDDED-----------EDEEEEDDENGDSSEDGGDSSESSSEDESED 683

Query: 1464 LLEEGEDGEDEDSDADEEVELILGDTDSSDNSDLEDD 1500
              E  ED EDED D D++ +       SS +S    D
Sbjct: 684  GDENEEDDEDEDDDEDDDEDEDNESEGSSSSSSSSGD 720


>gi|115529451 upstream binding transcription factor, RNA polymerase I
            isoform b [Homo sapiens]
          Length = 727

 Score = 61.2 bits (147), Expect = 7e-09
 Identities = 32/101 (31%), Positives = 56/101 (55%), Gaps = 13/101 (12%)

Query: 1395 AEDEDEEEDQEEEEQEEEDDDEDDDDTDDLDELDTDQLLEAELEEDDNNENAGEDGDNDF 1454
            +E++DEE++ +E+E EEE+DDE+ D ++D  +  ++   E E E+ D NE   ED D+D 
Sbjct: 640  SEEDDEEDEDDEDEDEEEEDDENGDSSEDGGD-SSESSSEDESEDGDENEEDDEDEDDD- 697

Query: 1455 SPSDEELANLLEEGEDGEDEDSDADEEVELILGDTDSSDNS 1495
                       E+ ++ ED +S+         GD+  SD++
Sbjct: 698  -----------EDDDEDEDNESEGSSSSSSSSGDSSDSDSN 727



 Score = 57.8 bits (138), Expect = 8e-08
 Identities = 36/97 (37%), Positives = 51/97 (52%), Gaps = 12/97 (12%)

Query: 1405 EEEEQEEEDDDEDDDDTDDLDELDTDQLLEAELEEDDNNENAGED-GDNDFSPSDEELAN 1463
            + + + EEDD+ED+DD D           E E EEDD N ++ ED GD+  S S++E  +
Sbjct: 635  QSKSESEEDDEEDEDDED-----------EDEEEEDDENGDSSEDGGDSSESSSEDESED 683

Query: 1464 LLEEGEDGEDEDSDADEEVELILGDTDSSDNSDLEDD 1500
              E  ED EDED D D++ +       SS +S    D
Sbjct: 684  GDENEEDDEDEDDDEDDDEDEDNESEGSSSSSSSSGD 720


>gi|7657671 upstream binding transcription factor, RNA polymerase I
            isoform a [Homo sapiens]
          Length = 764

 Score = 61.2 bits (147), Expect = 7e-09
 Identities = 32/101 (31%), Positives = 56/101 (55%), Gaps = 13/101 (12%)

Query: 1395 AEDEDEEEDQEEEEQEEEDDDEDDDDTDDLDELDTDQLLEAELEEDDNNENAGEDGDNDF 1454
            +E++DEE++ +E+E EEE+DDE+ D ++D  +  ++   E E E+ D NE   ED D+D 
Sbjct: 677  SEEDDEEDEDDEDEDEEEEDDENGDSSEDGGD-SSESSSEDESEDGDENEEDDEDEDDD- 734

Query: 1455 SPSDEELANLLEEGEDGEDEDSDADEEVELILGDTDSSDNS 1495
                       E+ ++ ED +S+         GD+  SD++
Sbjct: 735  -----------EDDDEDEDNESEGSSSSSSSSGDSSDSDSN 764



 Score = 57.8 bits (138), Expect = 8e-08
 Identities = 36/97 (37%), Positives = 51/97 (52%), Gaps = 12/97 (12%)

Query: 1405 EEEEQEEEDDDEDDDDTDDLDELDTDQLLEAELEEDDNNENAGED-GDNDFSPSDEELAN 1463
            + + + EEDD+ED+DD D           E E EEDD N ++ ED GD+  S S++E  +
Sbjct: 672  QSKSESEEDDEEDEDDED-----------EDEEEEDDENGDSSEDGGDSSESSSEDESED 720

Query: 1464 LLEEGEDGEDEDSDADEEVELILGDTDSSDNSDLEDD 1500
              E  ED EDED D D++ +       SS +S    D
Sbjct: 721  GDENEEDDEDEDDDEDDDEDEDNESEGSSSSSSSSGD 757


>gi|239756368 PREDICTED: similar to acidic (leucine-rich) nuclear
            phosphoprotein 32 family, member B [Homo sapiens]
          Length = 272

 Score = 60.8 bits (146), Expect = 9e-09
 Identities = 35/113 (30%), Positives = 62/113 (54%), Gaps = 9/113 (7%)

Query: 1387 YEVGRQRLAEDEDEEEDQEEEEQEEEDDDEDDDDTDDLDELDTDQLLEAELEEDDNNENA 1446
            Y+   Q   + + + +  ++EE++EE +DE D + +D +E + D+      EED++ +  
Sbjct: 168  YDPEDQEAPDSDAQVDGVDKEEEDEEGEDEKDXENEDGEEEELDE------EEDEDEDVE 221

Query: 1447 GEDGDNDFSPSDEELANLLEEGEDGEDEDSDADEEVELILGDTDSSDNSDLED 1499
            G+D  ++ S  +EE    L++ ED EDED D +EE E   G+    +  D ED
Sbjct: 222  GDDDKDEVSEEEEEFG--LDKDEDDEDEDEDEEEE-ESGKGENRKRETDDEED 271



 Score = 46.2 bits (108), Expect = 2e-04
 Identities = 29/98 (29%), Positives = 50/98 (51%), Gaps = 12/98 (12%)

Query: 1403 DQEEEEQEEEDDDEDDDDTDDLDELDTDQLLEAELEEDDNNENAGEDGDNDFSPSDEELA 1462
            D E++E  + D   D  D ++ DE       E E E+D  NE+  E+  ++    DE++ 
Sbjct: 169  DPEDQEAPDSDAQVDGVDKEEEDE-------EGEDEKDXENEDGEEEELDEEEDEDEDV- 220

Query: 1463 NLLEEGEDGEDEDSDADEEVELILGDTDSSDNSDLEDD 1500
                EG+D +DE S+ +EE  L   + D  ++ D E++
Sbjct: 221  ----EGDDDKDEVSEEEEEFGLDKDEDDEDEDEDEEEE 254



 Score = 37.0 bits (84), Expect = 0.14
 Identities = 29/92 (31%), Positives = 50/92 (54%), Gaps = 16/92 (17%)

Query: 1417 DDDDTDDLDELDTDQLLEAELEEDDNNENAGEDGDNDFSPSDEELANLLEEGEDGE-DED 1475
            D  D +D +  D+D  ++   +E+++ E  GED        +++  N  E+GE+ E DE+
Sbjct: 166  DTYDPEDQEAPDSDAQVDGVDKEEEDEE--GED--------EKDXEN--EDGEEEELDEE 213

Query: 1476 SDADEEVELILGDTDSSDNSDLEDDIILSLNE 1507
             D DE+VE   GD D  + S+ E++  L  +E
Sbjct: 214  EDEDEDVE---GDDDKDEVSEEEEEFGLDKDE 242


>gi|239750893 PREDICTED: similar to acidic (leucine-rich) nuclear
            phosphoprotein 32 family, member B [Homo sapiens]
          Length = 272

 Score = 60.8 bits (146), Expect = 9e-09
 Identities = 35/113 (30%), Positives = 62/113 (54%), Gaps = 9/113 (7%)

Query: 1387 YEVGRQRLAEDEDEEEDQEEEEQEEEDDDEDDDDTDDLDELDTDQLLEAELEEDDNNENA 1446
            Y+   Q   + + + +  ++EE++EE +DE D + +D +E + D+      EED++ +  
Sbjct: 168  YDPEDQEAPDSDAQVDGVDKEEEDEEGEDEKDXENEDGEEEELDE------EEDEDEDVE 221

Query: 1447 GEDGDNDFSPSDEELANLLEEGEDGEDEDSDADEEVELILGDTDSSDNSDLED 1499
            G+D  ++ S  +EE    L++ ED EDED D +EE E   G+    +  D ED
Sbjct: 222  GDDDKDEVSEEEEEFG--LDKDEDDEDEDEDEEEE-ESGKGENRKRETDDEED 271



 Score = 46.2 bits (108), Expect = 2e-04
 Identities = 29/98 (29%), Positives = 50/98 (51%), Gaps = 12/98 (12%)

Query: 1403 DQEEEEQEEEDDDEDDDDTDDLDELDTDQLLEAELEEDDNNENAGEDGDNDFSPSDEELA 1462
            D E++E  + D   D  D ++ DE       E E E+D  NE+  E+  ++    DE++ 
Sbjct: 169  DPEDQEAPDSDAQVDGVDKEEEDE-------EGEDEKDXENEDGEEEELDEEEDEDEDV- 220

Query: 1463 NLLEEGEDGEDEDSDADEEVELILGDTDSSDNSDLEDD 1500
                EG+D +DE S+ +EE  L   + D  ++ D E++
Sbjct: 221  ----EGDDDKDEVSEEEEEFGLDKDEDDEDEDEDEEEE 254



 Score = 37.0 bits (84), Expect = 0.14
 Identities = 29/92 (31%), Positives = 50/92 (54%), Gaps = 16/92 (17%)

Query: 1417 DDDDTDDLDELDTDQLLEAELEEDDNNENAGEDGDNDFSPSDEELANLLEEGEDGE-DED 1475
            D  D +D +  D+D  ++   +E+++ E  GED        +++  N  E+GE+ E DE+
Sbjct: 166  DTYDPEDQEAPDSDAQVDGVDKEEEDEE--GED--------EKDXEN--EDGEEEELDEE 213

Query: 1476 SDADEEVELILGDTDSSDNSDLEDDIILSLNE 1507
             D DE+VE   GD D  + S+ E++  L  +E
Sbjct: 214  EDEDEDVE---GDDDKDEVSEEEEEFGLDKDE 242


>gi|214010181 amyloid beta (A4) precursor-like protein 2 isoform 2
            [Homo sapiens]
          Length = 751

 Score = 60.1 bits (144), Expect = 2e-08
 Identities = 33/95 (34%), Positives = 50/95 (52%), Gaps = 7/95 (7%)

Query: 1398 EDEEEDQEEEEQEEEDDDEDDDDTDDLDELDTDQLLEAELEEDDNNENAGEDGDND---- 1453
            E+EEED+EEEE+E+E++D D   ++   E D +   EA ++EDD +E  GE+   D    
Sbjct: 215  EEEEEDEEEEEEEDEEEDYDVYKSEFPTEADLEDFTEAAVDEDDEDEEEGEEVVEDRDYY 274

Query: 1454 ---FSPSDEELANLLEEGEDGEDEDSDADEEVELI 1485
               F   D    N  E G DG   D +   +V+ +
Sbjct: 275  YDTFKGDDYNEENPTEPGSDGTMSDKEITHDVKAV 309



 Score = 36.6 bits (83), Expect = 0.19
 Identities = 24/86 (27%), Positives = 42/86 (48%), Gaps = 27/86 (31%)

Query: 1405 EEEEQEEEDDDEDDDDTDDLDELDTDQLLEAELEEDDNNENAGEDGDNDFSPSDEELANL 1464
            +EEE+E+E+++E++D+ +D D   ++   EA+LE              DF+         
Sbjct: 214  KEEEEEDEEEEEEEDEEEDYDVYKSEFPTEADLE--------------DFT--------- 250

Query: 1465 LEEGEDGEDEDSDADEEVELILGDTD 1490
                E   DED + +EE E ++ D D
Sbjct: 251  ----EAAVDEDDEDEEEGEEVVEDRD 272



 Score = 35.0 bits (79), Expect = 0.55
 Identities = 25/98 (25%), Positives = 46/98 (46%), Gaps = 28/98 (28%)

Query: 1389 VGRQRLAEDEDEEEDQEEEEQ-----------------------EEEDDDEDDDDTDDLD 1425
            V ++   EDE+EEE+++EEE                        E+++D+E+ ++  +  
Sbjct: 212  VSKEEEEEDEEEEEEEDEEEDYDVYKSEFPTEADLEDFTEAAVDEDDEDEEEGEEVVE-- 269

Query: 1426 ELDTDQLLEAELEEDDNNENAGEDGDNDFSPSDEELAN 1463
              D D   +    +D N EN  E G +D + SD+E+ +
Sbjct: 270  --DRDYYYDTFKGDDYNEENPTEPG-SDGTMSDKEITH 304


>gi|4502147 amyloid beta (A4) precursor-like protein 2 isoform 1 [Homo
            sapiens]
          Length = 763

 Score = 60.1 bits (144), Expect = 2e-08
 Identities = 33/95 (34%), Positives = 50/95 (52%), Gaps = 7/95 (7%)

Query: 1398 EDEEEDQEEEEQEEEDDDEDDDDTDDLDELDTDQLLEAELEEDDNNENAGEDGDND---- 1453
            E+EEED+EEEE+E+E++D D   ++   E D +   EA ++EDD +E  GE+   D    
Sbjct: 215  EEEEEDEEEEEEEDEEEDYDVYKSEFPTEADLEDFTEAAVDEDDEDEEEGEEVVEDRDYY 274

Query: 1454 ---FSPSDEELANLLEEGEDGEDEDSDADEEVELI 1485
               F   D    N  E G DG   D +   +V+ +
Sbjct: 275  YDTFKGDDYNEENPTEPGSDGTMSDKEITHDVKAV 309



 Score = 36.6 bits (83), Expect = 0.19
 Identities = 24/86 (27%), Positives = 42/86 (48%), Gaps = 27/86 (31%)

Query: 1405 EEEEQEEEDDDEDDDDTDDLDELDTDQLLEAELEEDDNNENAGEDGDNDFSPSDEELANL 1464
            +EEE+E+E+++E++D+ +D D   ++   EA+LE              DF+         
Sbjct: 214  KEEEEEDEEEEEEEDEEEDYDVYKSEFPTEADLE--------------DFT--------- 250

Query: 1465 LEEGEDGEDEDSDADEEVELILGDTD 1490
                E   DED + +EE E ++ D D
Sbjct: 251  ----EAAVDEDDEDEEEGEEVVEDRD 272



 Score = 35.0 bits (79), Expect = 0.55
 Identities = 25/98 (25%), Positives = 46/98 (46%), Gaps = 28/98 (28%)

Query: 1389 VGRQRLAEDEDEEEDQEEEEQ-----------------------EEEDDDEDDDDTDDLD 1425
            V ++   EDE+EEE+++EEE                        E+++D+E+ ++  +  
Sbjct: 212  VSKEEEEEDEEEEEEEDEEEDYDVYKSEFPTEADLEDFTEAAVDEDDEDEEEGEEVVE-- 269

Query: 1426 ELDTDQLLEAELEEDDNNENAGEDGDNDFSPSDEELAN 1463
              D D   +    +D N EN  E G +D + SD+E+ +
Sbjct: 270  --DRDYYYDTFKGDDYNEENPTEPG-SDGTMSDKEITH 304


>gi|214010183 amyloid beta (A4) precursor-like protein 2 isoform 3
            [Homo sapiens]
          Length = 695

 Score = 59.7 bits (143), Expect = 2e-08
 Identities = 33/94 (35%), Positives = 50/94 (53%), Gaps = 7/94 (7%)

Query: 1398 EDEEEDQEEEEQEEEDDDEDDDDTDDLDELDTDQLLEAELEEDDNNENAGEDGDND---- 1453
            E+EEED+EEEE+E+E++D D   ++   E D +   EA ++EDD +E  GE+   D    
Sbjct: 215  EEEEEDEEEEEEEDEEEDYDVYKSEFPTEADLEDFTEAAVDEDDEDEEEGEEVVEDRDYY 274

Query: 1454 ---FSPSDEELANLLEEGEDGEDEDSDADEEVEL 1484
               F   D    N  E G DG   D +   +V++
Sbjct: 275  YDTFKGDDYNEENPTEPGSDGTMSDKEITHDVKV 308



 Score = 36.6 bits (83), Expect = 0.19
 Identities = 24/86 (27%), Positives = 42/86 (48%), Gaps = 27/86 (31%)

Query: 1405 EEEEQEEEDDDEDDDDTDDLDELDTDQLLEAELEEDDNNENAGEDGDNDFSPSDEELANL 1464
            +EEE+E+E+++E++D+ +D D   ++   EA+LE              DF+         
Sbjct: 214  KEEEEEDEEEEEEEDEEEDYDVYKSEFPTEADLE--------------DFT--------- 250

Query: 1465 LEEGEDGEDEDSDADEEVELILGDTD 1490
                E   DED + +EE E ++ D D
Sbjct: 251  ----EAAVDEDDEDEEEGEEVVEDRD 272



 Score = 35.0 bits (79), Expect = 0.55
 Identities = 25/98 (25%), Positives = 46/98 (46%), Gaps = 28/98 (28%)

Query: 1389 VGRQRLAEDEDEEEDQEEEEQ-----------------------EEEDDDEDDDDTDDLD 1425
            V ++   EDE+EEE+++EEE                        E+++D+E+ ++  +  
Sbjct: 212  VSKEEEEEDEEEEEEEDEEEDYDVYKSEFPTEADLEDFTEAAVDEDDEDEEEGEEVVE-- 269

Query: 1426 ELDTDQLLEAELEEDDNNENAGEDGDNDFSPSDEELAN 1463
              D D   +    +D N EN  E G +D + SD+E+ +
Sbjct: 270  --DRDYYYDTFKGDDYNEENPTEPG-SDGTMSDKEITH 304


>gi|61676188 HECT, UBA and WWE domain containing 1 [Homo sapiens]
          Length = 4374

 Score = 58.5 bits (140), Expect = 5e-08
 Identities = 26/51 (50%), Positives = 39/51 (76%)

Query: 1396 EDEDEEEDQEEEEQEEEDDDEDDDDTDDLDELDTDQLLEAELEEDDNNENA 1446
            EDED+ +D+EEEE+E+E+DD++DD+ ++ DE D D   E EL+ED  + NA
Sbjct: 2426 EDEDDSQDEEEEEEEDEEDDQEDDEGEEGDEDDDDDGSEMELDEDYPDMNA 2476



 Score = 49.3 bits (116), Expect = 3e-05
 Identities = 31/107 (28%), Positives = 51/107 (47%), Gaps = 18/107 (16%)

Query: 1400 EEEDQEEEEQEEEDDDEDDDDTDDLDELDTDQLLEAELEEDDNNENAGEDGDNDFSPSDE 1459
            + ED+EE  QEE+    ++D+ D  DE +     E E EEDD  ++ GE+GD D      
Sbjct: 2408 DPEDEEEHTQEEDSSGSNEDEDDSQDEEEE----EEEDEEDDQEDDEGEEGDED------ 2457

Query: 1460 ELANLLEEGEDGEDEDSDADEEVELILGDTDSSDNSDLEDDIILSLN 1506
                   + +DG + + D D   ++        +  D EDD+I+  +
Sbjct: 2458 -------DDDDGSEMELDEDYP-DMNASPLVRFERFDREDDLIIEFD 2496



 Score = 37.7 bits (86), Expect = 0.085
 Identities = 20/64 (31%), Positives = 34/64 (53%)

Query: 1396 EDEDEEEDQEEEEQEEEDDDEDDDDTDDLDELDTDQLLEAELEEDDNNENAGEDGDNDFS 1455
            ++ED++ED E EE +E+DDD+  +   D D  D +       E  D  ++   + DN FS
Sbjct: 2441 DEEDDQEDDEGEEGDEDDDDDGSEMELDEDYPDMNASPLVRFERFDREDDLIIEFDNMFS 2500

Query: 1456 PSDE 1459
             + +
Sbjct: 2501 SATD 2504



 Score = 32.3 bits (72), Expect = 3.6
 Identities = 33/116 (28%), Positives = 47/116 (40%), Gaps = 30/116 (25%)

Query: 1409 QEEEDDDEDDDDTDDLDELD----TDQLLEAELEEDDNNENA------------------ 1446
            QE + ++E +D  D+L E D       ++ +   ED++ E+                   
Sbjct: 2340 QEMQVENELEDLIDELLERDGGSGNSTIIVSRSGEDESQEDVLMDEAPSNLSQASTLQAN 2399

Query: 1447 GEDGDNDFSPSDEELANLLEEGEDG--EDEDSDADEEVELILGDTDSSDNSDLEDD 1500
             ED  N   P DEE  +  EE   G  EDED   DEE E      +  +  D EDD
Sbjct: 2400 REDSMNILDPEDEE-EHTQEEDSSGSNEDEDDSQDEEEE-----EEEDEEDDQEDD 2449


>gi|155030232 proline, glutamic acid and leucine rich protein 1 [Homo
            sapiens]
          Length = 1130

 Score = 57.8 bits (138), Expect = 8e-08
 Identities = 33/89 (37%), Positives = 57/89 (64%), Gaps = 12/89 (13%)

Query: 1395 AEDEDEEEDQEEEEQEEEDDDEDDDDTDDLDELDTDQLLEAELEEDDNNENAGEDGDNDF 1454
            + DE+EEE++EEEE+EEE+++E++D  +  +E D ++  E E EE+       E+ + +F
Sbjct: 885  SSDEEEEEEEEEEEEEEEEEEEEEDFEE--EEEDEEEYFEEEEEEE-------EEFEEEF 935

Query: 1455 SPSDEELANLLEEGEDGEDEDSDADEEVE 1483
               +EE   L EE E+ ++E+ +  EEVE
Sbjct: 936  ---EEEEGELEEEEEEEDEEEEEELEEVE 961



 Score = 49.7 bits (117), Expect = 2e-05
 Identities = 27/77 (35%), Positives = 47/77 (61%), Gaps = 6/77 (7%)

Query: 1396 EDEDEEEDQEEEEQEEEDDDEDDDDTDDLDELDTDQLLEAELEEDDNNENAGEDGDNDFS 1455
            E+E+EEE++EEEE+E+ +++E+D++    +E + ++  E E EE++      E+ +    
Sbjct: 894  EEEEEEEEEEEEEEEDFEEEEEDEEEYFEEEEEEEEEFEEEFEEEEGELEEEEEEE---- 949

Query: 1456 PSDEELANLLEEGEDGE 1472
              DEE    LEE ED E
Sbjct: 950  --DEEEEEELEEVEDLE 964



 Score = 48.1 bits (113), Expect = 6e-05
 Identities = 25/80 (31%), Positives = 48/80 (60%)

Query: 1396 EDEDEEEDQEEEEQEEEDDDEDDDDTDDLDELDTDQLLEAELEEDDNNENAGEDGDNDFS 1455
            E+E+EEE++EEEE++ E+++ED+++  + +E + ++  E   EE+   E   E+ D +  
Sbjct: 895  EEEEEEEEEEEEEEDFEEEEEDEEEYFEEEEEEEEEFEEEFEEEEGELEEEEEEEDEEEE 954

Query: 1456 PSDEELANLLEEGEDGEDED 1475
               EE+ +L      GE E+
Sbjct: 955  EELEEVEDLEFGTAGGEVEE 974



 Score = 38.5 bits (88), Expect = 0.050
 Identities = 19/68 (27%), Positives = 36/68 (52%)

Query: 1434 EAELEEDDNNENAGEDGDNDFSPSDEELANLLEEGEDGEDEDSDADEEVELILGDTDSSD 1493
            E E EE++  E   E+ + DF   +E+     EE E+ E+E  +  EE E  L + +  +
Sbjct: 890  EEEEEEEEEEEEEEEEEEEDFEEEEEDEEEYFEEEEEEEEEFEEEFEEEEGELEEEEEEE 949

Query: 1494 NSDLEDDI 1501
            + + E+++
Sbjct: 950  DEEEEEEL 957



 Score = 38.5 bits (88), Expect = 0.050
 Identities = 32/107 (29%), Positives = 49/107 (45%), Gaps = 23/107 (21%)

Query: 1396 EDEDE---EEDQEEEEQEEEDDDEDDDDTDDLDELDTDQLLEAELEEDDNNENAGEDGDN 1452
            EDE+E   EE++EEEE EEE ++E+ +  ++ +E D ++  E E  ED     AG + + 
Sbjct: 915  EDEEEYFEEEEEEEEEFEEEFEEEEGELEEEEEEEDEEEEEELEEVEDLEFGTAGGEVEE 974

Query: 1453 DFSP--------------------SDEELANLLEEGEDGEDEDSDAD 1479
               P                     + E   LLE  E G +E+  AD
Sbjct: 975  GAPPPPTLPPALPPPESPPKVQPEPEPEPGLLLEVEEPGTEEERGAD 1021


>gi|4503257 death-domain associated protein isoform a [Homo sapiens]
          Length = 740

 Score = 55.5 bits (132), Expect = 4e-07
 Identities = 25/61 (40%), Positives = 41/61 (67%)

Query: 1396 EDEDEEEDQEEEEQEEEDDDEDDDDTDDLDELDTDQLLEAELEEDDNNENAGEDGDNDFS 1455
            +DED+EE  EEEE+EEE+++E+  D+++ ++L+  Q  + + EE+D  E A    D D S
Sbjct: 436  DDEDDEESDEEEEEEEEEEEEEATDSEEEEDLEQMQEGQEDDEEEDEEEEAAAGKDGDKS 495

Query: 1456 P 1456
            P
Sbjct: 496  P 496



 Score = 52.0 bits (123), Expect = 4e-06
 Identities = 27/64 (42%), Positives = 44/64 (68%), Gaps = 5/64 (7%)

Query: 1391 RQRLAEDEDEEEDQEEEEQEEEDDDE--DDDDTDDLDELDTDQLLEAELEEDDNNE-NAG 1447
            R    +++DEE D+EEEE+EEE+++E  D ++ +DL+++   Q  E + EED+  E  AG
Sbjct: 432  RAETDDEDDEESDEEEEEEEEEEEEEATDSEEEEDLEQMQEGQ--EDDEEEDEEEEAAAG 489

Query: 1448 EDGD 1451
            +DGD
Sbjct: 490  KDGD 493



 Score = 45.8 bits (107), Expect = 3e-04
 Identities = 30/105 (28%), Positives = 52/105 (49%), Gaps = 37/105 (35%)

Query: 1395 AEDEDEEEDQEEEEQEEEDDDEDDDDTDDLDELDTDQLLEAELEEDDNNENAGEDGDNDF 1454
            AE +DE++++ +EE+EEE+++E+++ TD            +E EED              
Sbjct: 433  AETDDEDDEESDEEEEEEEEEEEEEATD------------SEEEED-------------- 466

Query: 1455 SPSDEELANLLEEGEDGEDEDSDADEEVELILG-DTDSSDNSDLE 1498
                      LE+ ++G+++D + DEE E   G D D S  S L+
Sbjct: 467  ----------LEQMQEGQEDDEEEDEEEEAAAGKDGDKSPMSSLQ 501



 Score = 35.8 bits (81), Expect = 0.32
 Identities = 26/112 (23%), Positives = 46/112 (41%), Gaps = 6/112 (5%)

Query: 1389 VGRQRLAEDEDEEEDQEEEEQEEEDDDEDDDDTDDLDELDTDQLLEAELEEDDNNENAGE 1448
            + +  + +D+ EE ++++     +       DT +   LD+ +       +   + +  E
Sbjct: 376  ISKYAMLQDKSEEGERKKRRARLQGTSSHSADTPEAS-LDSGEGPSGMASQGCPSASRAE 434

Query: 1449 DGDNDFSPSDEELANLLEEGEDGEDEDSDADEEVELILGDTDSSDNSDLEDD 1500
              D D   SDEE     EE E+ E+E+   D E E  L         D E+D
Sbjct: 435  TDDEDDEESDEE-----EEEEEEEEEEEATDSEEEEDLEQMQEGQEDDEEED 481


>gi|215422388 death-domain associated protein isoform a [Homo sapiens]
          Length = 740

 Score = 55.5 bits (132), Expect = 4e-07
 Identities = 25/61 (40%), Positives = 41/61 (67%)

Query: 1396 EDEDEEEDQEEEEQEEEDDDEDDDDTDDLDELDTDQLLEAELEEDDNNENAGEDGDNDFS 1455
            +DED+EE  EEEE+EEE+++E+  D+++ ++L+  Q  + + EE+D  E A    D D S
Sbjct: 436  DDEDDEESDEEEEEEEEEEEEEATDSEEEEDLEQMQEGQEDDEEEDEEEEAAAGKDGDKS 495

Query: 1456 P 1456
            P
Sbjct: 496  P 496



 Score = 52.0 bits (123), Expect = 4e-06
 Identities = 27/64 (42%), Positives = 44/64 (68%), Gaps = 5/64 (7%)

Query: 1391 RQRLAEDEDEEEDQEEEEQEEEDDDE--DDDDTDDLDELDTDQLLEAELEEDDNNE-NAG 1447
            R    +++DEE D+EEEE+EEE+++E  D ++ +DL+++   Q  E + EED+  E  AG
Sbjct: 432  RAETDDEDDEESDEEEEEEEEEEEEEATDSEEEEDLEQMQEGQ--EDDEEEDEEEEAAAG 489

Query: 1448 EDGD 1451
            +DGD
Sbjct: 490  KDGD 493



 Score = 45.8 bits (107), Expect = 3e-04
 Identities = 30/105 (28%), Positives = 52/105 (49%), Gaps = 37/105 (35%)

Query: 1395 AEDEDEEEDQEEEEQEEEDDDEDDDDTDDLDELDTDQLLEAELEEDDNNENAGEDGDNDF 1454
            AE +DE++++ +EE+EEE+++E+++ TD            +E EED              
Sbjct: 433  AETDDEDDEESDEEEEEEEEEEEEEATD------------SEEEED-------------- 466

Query: 1455 SPSDEELANLLEEGEDGEDEDSDADEEVELILG-DTDSSDNSDLE 1498
                      LE+ ++G+++D + DEE E   G D D S  S L+
Sbjct: 467  ----------LEQMQEGQEDDEEEDEEEEAAAGKDGDKSPMSSLQ 501



 Score = 35.8 bits (81), Expect = 0.32
 Identities = 26/112 (23%), Positives = 46/112 (41%), Gaps = 6/112 (5%)

Query: 1389 VGRQRLAEDEDEEEDQEEEEQEEEDDDEDDDDTDDLDELDTDQLLEAELEEDDNNENAGE 1448
            + +  + +D+ EE ++++     +       DT +   LD+ +       +   + +  E
Sbjct: 376  ISKYAMLQDKSEEGERKKRRARLQGTSSHSADTPEAS-LDSGEGPSGMASQGCPSASRAE 434

Query: 1449 DGDNDFSPSDEELANLLEEGEDGEDEDSDADEEVELILGDTDSSDNSDLEDD 1500
              D D   SDEE     EE E+ E+E+   D E E  L         D E+D
Sbjct: 435  TDDEDDEESDEE-----EEEEEEEEEEEATDSEEEEDLEQMQEGQEDDEEED 481


>gi|215422366 death-domain associated protein isoform b [Homo sapiens]
          Length = 752

 Score = 55.5 bits (132), Expect = 4e-07
 Identities = 25/61 (40%), Positives = 41/61 (67%)

Query: 1396 EDEDEEEDQEEEEQEEEDDDEDDDDTDDLDELDTDQLLEAELEEDDNNENAGEDGDNDFS 1455
            +DED+EE  EEEE+EEE+++E+  D+++ ++L+  Q  + + EE+D  E A    D D S
Sbjct: 448  DDEDDEESDEEEEEEEEEEEEEATDSEEEEDLEQMQEGQEDDEEEDEEEEAAAGKDGDKS 507

Query: 1456 P 1456
            P
Sbjct: 508  P 508



 Score = 52.0 bits (123), Expect = 4e-06
 Identities = 27/64 (42%), Positives = 44/64 (68%), Gaps = 5/64 (7%)

Query: 1391 RQRLAEDEDEEEDQEEEEQEEEDDDE--DDDDTDDLDELDTDQLLEAELEEDDNNE-NAG 1447
            R    +++DEE D+EEEE+EEE+++E  D ++ +DL+++   Q  E + EED+  E  AG
Sbjct: 444  RAETDDEDDEESDEEEEEEEEEEEEEATDSEEEEDLEQMQEGQ--EDDEEEDEEEEAAAG 501

Query: 1448 EDGD 1451
            +DGD
Sbjct: 502  KDGD 505



 Score = 45.8 bits (107), Expect = 3e-04
 Identities = 30/105 (28%), Positives = 52/105 (49%), Gaps = 37/105 (35%)

Query: 1395 AEDEDEEEDQEEEEQEEEDDDEDDDDTDDLDELDTDQLLEAELEEDDNNENAGEDGDNDF 1454
            AE +DE++++ +EE+EEE+++E+++ TD            +E EED              
Sbjct: 445  AETDDEDDEESDEEEEEEEEEEEEEATD------------SEEEED-------------- 478

Query: 1455 SPSDEELANLLEEGEDGEDEDSDADEEVELILG-DTDSSDNSDLE 1498
                      LE+ ++G+++D + DEE E   G D D S  S L+
Sbjct: 479  ----------LEQMQEGQEDDEEEDEEEEAAAGKDGDKSPMSSLQ 513



 Score = 35.8 bits (81), Expect = 0.32
 Identities = 26/112 (23%), Positives = 46/112 (41%), Gaps = 6/112 (5%)

Query: 1389 VGRQRLAEDEDEEEDQEEEEQEEEDDDEDDDDTDDLDELDTDQLLEAELEEDDNNENAGE 1448
            + +  + +D+ EE ++++     +       DT +   LD+ +       +   + +  E
Sbjct: 388  ISKYAMLQDKSEEGERKKRRARLQGTSSHSADTPEAS-LDSGEGPSGMASQGCPSASRAE 446

Query: 1449 DGDNDFSPSDEELANLLEEGEDGEDEDSDADEEVELILGDTDSSDNSDLEDD 1500
              D D   SDEE     EE E+ E+E+   D E E  L         D E+D
Sbjct: 447  TDDEDDEESDEE-----EEEEEEEEEEEATDSEEEEDLEQMQEGQEDDEEED 493


>gi|17975763 myelin transcription factor 1 [Homo sapiens]
          Length = 1121

 Score = 55.5 bits (132), Expect = 4e-07
 Identities = 33/123 (26%), Positives = 62/123 (50%), Gaps = 24/123 (19%)

Query: 1394 LAEDEDEEEDQEEEEQEEEDDDEDDDDTDDLDELDTDQLLEAELEEDDNNENAGED---- 1449
            L+ +E++EE++EEEE+EEED++E++++ ++ +E + ++  E E EE++  E A  D    
Sbjct: 255  LSHEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEAAPDVIFQ 314

Query: 1450 ---------------GDNDFSPSDEELANLLEEGEDGEDEDSDADEEVELILGDTDSSDN 1494
                           G    SP  E    +    +D +DED+ + +        TD S+ 
Sbjct: 315  EDTSHTSAQKAPELRGPESPSPKPEYSVIVEVRSDDDKDEDTHSRKSTV-----TDESEM 369

Query: 1495 SDL 1497
             D+
Sbjct: 370  QDM 372



 Score = 35.0 bits (79), Expect = 0.55
 Identities = 25/111 (22%), Positives = 49/111 (44%)

Query: 1390 GRQRLAEDEDEEEDQEEEEQEEEDDDEDDDDTDDLDELDTDQLLEAELEEDDNNENAGED 1449
            G   L ++  E    EE E+      ED ++  ++    +  L    LE+  + E++ + 
Sbjct: 193  GIVHLLQEAAEGAASEEGEKGLFIQPEDAEEVVEVTTERSQDLCPQSLEDAASEESSKQK 252

Query: 1450 GDNDFSPSDEELANLLEEGEDGEDEDSDADEEVELILGDTDSSDNSDLEDD 1500
            G       DEE     EE E+ E+E+ + +EE E    + +  +  + E++
Sbjct: 253  GILSHEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEEEEEEE 303



 Score = 34.7 bits (78), Expect = 0.72
 Identities = 27/114 (23%), Positives = 51/114 (44%), Gaps = 3/114 (2%)

Query: 1392 QRLAEDEDEEEDQEEEEQEEEDDDEDDDDTDDLDELDTDQLLEAELEEDDNNEN---AGE 1448
            Q  AE    EE ++    + ED +E  + T +  +    Q LE    E+ + +    + E
Sbjct: 199  QEAAEGAASEEGEKGLFIQPEDAEEVVEVTTERSQDLCPQSLEDAASEESSKQKGILSHE 258

Query: 1449 DGDNDFSPSDEELANLLEEGEDGEDEDSDADEEVELILGDTDSSDNSDLEDDII 1502
            + D +    +EE     EE E+ E+E+ + +EE E    + +  +  +   D+I
Sbjct: 259  EEDEEEEEEEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEAAPDVI 312


>gi|195546902 suppressor of Ty 5 homolog isoform b [Homo sapiens]
          Length = 1083

 Score = 54.7 bits (130), Expect = 7e-07
 Identities = 41/127 (32%), Positives = 62/127 (48%), Gaps = 15/127 (11%)

Query: 1390 GRQRLAEDEDEEEDQEEEEQEEEDDDEDDDDTDD--------LDELDTDQLLEAELEEDD 1441
            G ++  E EDEEE++EEEE +EE+++EDDD            LDE D D   E E + +D
Sbjct: 35   GSEKEEEPEDEEEEEEEEEYDEEEEEEDDDRPPKKPRHGGFILDEADVDDEYEDEDQWED 94

Query: 1442 NNENAGEDGDN-DFSPSDEE------LANLLEEGEDGEDEDSDADEEVELILGDTDSSDN 1494
              E+  E   N D    DE+      L NL  +  + E  +    +  +  +G+T    +
Sbjct: 95   GAEDILEKASNIDNVVLDEDRSGARRLQNLWRDQREEELGEYYMKKYAKSSVGETVYGGS 154

Query: 1495 SDLEDDI 1501
             +L DDI
Sbjct: 155  DELSDDI 161



 Score = 40.0 bits (92), Expect = 0.017
 Identities = 28/114 (24%), Positives = 51/114 (44%), Gaps = 7/114 (6%)

Query: 1394 LAEDEDEEEDQEEEEQEEEDDDEDDDDTDDLDELDTDQLLEAELEEDDNNENA----GED 1449
            +++ ED    +EE+ +   D +E + D +      +++  E E EE++  E       E+
Sbjct: 1    MSDSEDSNFSEEEDSERSSDGEEAEVDEERRSAAGSEKEEEPEDEEEEEEEEEYDEEEEE 60

Query: 1450 GDNDFSPSDEELANLLEEGEDGEDEDSDAD---EEVELILGDTDSSDNSDLEDD 1500
             D+D  P        + +  D +DE  D D   +  E IL    + DN  L++D
Sbjct: 61   EDDDRPPKKPRHGGFILDEADVDDEYEDEDQWEDGAEDILEKASNIDNVVLDED 114



 Score = 36.6 bits (83), Expect = 0.19
 Identities = 27/106 (25%), Positives = 54/106 (50%), Gaps = 22/106 (20%)

Query: 1388 EVGRQRLAEDEDEEEDQE-------EEEQEEEDDDEDDDD---TDDLDELDTDQ------ 1431
            E   +R ++ E+ E D+E       E+E+E ED++E++++    ++ +E D D+      
Sbjct: 12   EEDSERSSDGEEAEVDEERRSAAGSEKEEEPEDEEEEEEEEEYDEEEEEEDDDRPPKKPR 71

Query: 1432 -----LLEAELEEDDNNENAGEDGDNDFSPSDEELAN-LLEEGEDG 1471
                 L EA+++++  +E+  EDG  D       + N +L+E   G
Sbjct: 72   HGGFILDEADVDDEYEDEDQWEDGAEDILEKASNIDNVVLDEDRSG 117


>gi|114155142 nuclear pore complex-associated protein TPR [Homo
            sapiens]
          Length = 2363

 Score = 54.3 bits (129), Expect = 9e-07
 Identities = 33/87 (37%), Positives = 47/87 (54%), Gaps = 11/87 (12%)

Query: 1396 EDEDEEEDQEEEEQEEEDDDEDDDDTDDLDELDTDQLLEAELEEDDNNENAGEDGDNDFS 1455
            + +DEEED +E + E ED +ED++D DD DE DT    E E    D+NE  G    ND  
Sbjct: 1947 DSDDEEEDDDENDGEHEDYEEDEEDDDD-DEDDTGMGDEGE----DSNEGTGSADGNDGY 2001

Query: 1456 PSDEELANLLEEGEDGEDEDSDADEEV 1482
             +D+       EG DG D  ++ +E +
Sbjct: 2002 EADD------AEGGDGTDPGTETEESM 2022



 Score = 38.9 bits (89), Expect = 0.038
 Identities = 27/107 (25%), Positives = 45/107 (42%), Gaps = 12/107 (11%)

Query: 1402 EDQEEEEQE--------EEDDDEDDDDTDDLDELDTDQLLEAELEEDDNNENAGE----D 1449
            ED EE  Q         + D        D   + D   +++++ EE+D++EN GE    +
Sbjct: 1907 EDSEETSQSLQIDLGPLQSDQQTTTSSQDGQGKGDDVIVIDSDDEEEDDDENDGEHEDYE 1966

Query: 1450 GDNDFSPSDEELANLLEEGEDGEDEDSDADEEVELILGDTDSSDNSD 1496
             D +    DE+   + +EGED  +    AD        D +  D +D
Sbjct: 1967 EDEEDDDDDEDDTGMGDEGEDSNEGTGSADGNDGYEADDAEGGDGTD 2013



 Score = 33.5 bits (75), Expect = 1.6
 Identities = 29/113 (25%), Positives = 46/113 (40%), Gaps = 19/113 (16%)

Query: 1399 DEEEDQEEEEQEEEDDDEDD--------DDTDDLDELDTDQLLEAEL---EEDDNNENAG 1447
            +E  D E E Q    D +D         D T   D  +T Q L+ +L   + D     + 
Sbjct: 1874 EESTDGEVETQVYNQDSQDSIGEGVTQGDYTPMEDSEETSQSLQIDLGPLQSDQQTTTSS 1933

Query: 1448 EDGDNDFSPSDEELANLLEEGEDGEDEDSDADEEVELILGDTDSSDNSDLEDD 1500
            +DG       D+ +    ++ E+ +DE+    E+ E      D  D+ D EDD
Sbjct: 1934 QDGQGK---GDDVIVIDSDDEEEDDDENDGEHEDYE-----EDEEDDDDDEDD 1978


>gi|16445033 ACRC protein [Homo sapiens]
          Length = 691

 Score = 53.9 bits (128), Expect = 1e-06
 Identities = 26/115 (22%), Positives = 58/115 (50%), Gaps = 9/115 (7%)

Query: 1395 AEDEDEEEDQEEEEQEEEDDDEDDDDTDDLD---------ELDTDQLLEAELEEDDNNEN 1445
            ++D D  +D  ++  ++  DD  DD++DD D         ++  D   ++++ +D ++++
Sbjct: 183  SDDSDVPDDNSDDSSDDNSDDSSDDNSDDSDVPDDKSDDSDVPDDSSDDSDVPDDSSDDS 242

Query: 1446 AGEDGDNDFSPSDEELANLLEEGEDGEDEDSDADEEVELILGDTDSSDNSDLEDD 1500
               D  +D S + ++ ++  E  +D  D+    D+  +      DSSD+S+  DD
Sbjct: 243  EAPDDSSDDSEAPDDSSDDSEAPDDSSDDSEAPDDSSDDSEASDDSSDDSEASDD 297



 Score = 53.1 bits (126), Expect = 2e-06
 Identities = 28/106 (26%), Positives = 55/106 (51%), Gaps = 4/106 (3%)

Query: 1395 AEDEDEEEDQEEEEQEEEDDDEDDDDTDDLDELDTDQLLEAELEEDDNNENAGEDGDNDF 1454
            +E  D+  D  E   +  DD E  DD  D  E   D   ++++  DDN++++ +D  +D 
Sbjct: 146  SEAPDDNSDDSEAPDDNSDDSEAPDDNSDDSEAPDDNSDDSDVP-DDNSDDSSDDNSDDS 204

Query: 1455 SPSDEELANLLEEGEDGEDEDSDADEEVELILGDTDSSDNSDLEDD 1500
            S  + + +++ ++  D  D   D+ ++ ++     DSSD+S+  DD
Sbjct: 205  SDDNSDDSDVPDDKSDDSDVPDDSSDDSDV---PDDSSDDSEAPDD 247



 Score = 53.1 bits (126), Expect = 2e-06
 Identities = 27/103 (26%), Positives = 54/103 (52%), Gaps = 1/103 (0%)

Query: 1398 EDEEEDQEEEEQEEEDDDEDDDDTDDLDELDTDQLLEAELEEDDNNENAGEDGDNDFSPS 1457
            +D  +D +  + + +D D  DD +DD D  D D   ++E  +D ++++   D  +D S +
Sbjct: 206  DDNSDDSDVPDDKSDDSDVPDDSSDDSDVPD-DSSDDSEAPDDSSDDSEAPDDSSDDSEA 264

Query: 1458 DEELANLLEEGEDGEDEDSDADEEVELILGDTDSSDNSDLEDD 1500
             ++ ++  E  +D  D+   +D+  +      DSSD+S+  DD
Sbjct: 265  PDDSSDDSEAPDDSSDDSEASDDSSDDSEASDDSSDDSEAPDD 307



 Score = 52.4 bits (124), Expect = 3e-06
 Identities = 31/105 (29%), Positives = 49/105 (46%), Gaps = 4/105 (3%)

Query: 1396 EDEDEEEDQEEEEQEEEDDDEDDDDTDDLDELDTDQLLEAELEEDDNNENAGEDGDNDFS 1455
            E  D+  D  E   +  DD E  DD  D  E   D   ++E   DDN++++    DN   
Sbjct: 137  EVPDDNSDDSEAPDDNSDDSEAPDDNSDDSEAPDDNSDDSEAP-DDNSDDSDVPDDNSDD 195

Query: 1456 PSDEELANLLEEGEDGEDEDSDADEEVELILGDTDSSDNSDLEDD 1500
             SD+   +  ++  D  D   D  ++ ++     DSSD+SD+ DD
Sbjct: 196  SSDDNSDDSSDDNSDDSDVPDDKSDDSDV---PDDSSDDSDVPDD 237



 Score = 52.4 bits (124), Expect = 3e-06
 Identities = 26/102 (25%), Positives = 50/102 (49%)

Query: 1399 DEEEDQEEEEQEEEDDDEDDDDTDDLDELDTDQLLEAELEEDDNNENAGEDGDNDFSPSD 1458
            D+  D  +   +  DD E  DD+ D  E   D   ++E  +D ++++   D  +D S + 
Sbjct: 226  DDSSDDSDVPDDSSDDSEAPDDSSDDSEAPDDSSDDSEAPDDSSDDSEAPDDSSDDSEAS 285

Query: 1459 EELANLLEEGEDGEDEDSDADEEVELILGDTDSSDNSDLEDD 1500
            ++ ++  E  +D  D+    D++ +      D SD+SD+ DD
Sbjct: 286  DDSSDDSEASDDSSDDSEAPDDKSDDSDVPEDKSDDSDVPDD 327



 Score = 51.6 bits (122), Expect = 6e-06
 Identities = 25/103 (24%), Positives = 54/103 (52%), Gaps = 1/103 (0%)

Query: 1398 EDEEEDQEEEEQEEEDDDEDDDDTDDLDELDTDQLLEAELEEDDNNENAGEDGDNDFSPS 1457
            +D+ +D +  +   +D D  DD +DD +  D D   ++E  +D ++++   D  +D S +
Sbjct: 216  DDKSDDSDVPDDSSDDSDVPDDSSDDSEAPD-DSSDDSEAPDDSSDDSEAPDDSSDDSEA 274

Query: 1458 DEELANLLEEGEDGEDEDSDADEEVELILGDTDSSDNSDLEDD 1500
             ++ ++  E  +D  D+   +D+  +      D SD+SD+ +D
Sbjct: 275  PDDSSDDSEASDDSSDDSEASDDSSDDSEAPDDKSDDSDVPED 317



 Score = 51.2 bits (121), Expect = 7e-06
 Identities = 25/104 (24%), Positives = 52/104 (50%)

Query: 1397 DEDEEEDQEEEEQEEEDDDEDDDDTDDLDELDTDQLLEAELEEDDNNENAGEDGDNDFSP 1456
            D+ E  D   ++ +  DD+ DD   D+ D+   D   ++++ +D ++++   D  +D S 
Sbjct: 174  DDSEAPDDNSDDSDVPDDNSDDSSDDNSDDSSDDNSDDSDVPDDKSDDSDVPDDSSDDSD 233

Query: 1457 SDEELANLLEEGEDGEDEDSDADEEVELILGDTDSSDNSDLEDD 1500
              ++ ++  E  +D  D+    D+  +      DSSD+S+  DD
Sbjct: 234  VPDDSSDDSEAPDDSSDDSEAPDDSSDDSEAPDDSSDDSEAPDD 277



 Score = 48.5 bits (114), Expect = 5e-05
 Identities = 27/104 (25%), Positives = 51/104 (49%), Gaps = 7/104 (6%)

Query: 1398 EDEEEDQEEEEQEEEDDDEDDDDTDDLDELDTDQLLEAELEEDDNNENAGEDGD-NDFSP 1456
            +D  +D E  +   +D D  DD++DD  + ++D   +   ++ D  ++  +D D  D S 
Sbjct: 170  DDNSDDSEAPDDNSDDSDVPDDNSDDSSDDNSDDSSDDNSDDSDVPDDKSDDSDVPDDSS 229

Query: 1457 SDEELANLLEEGEDGEDEDSDADEEVELILGDTDSSDNSDLEDD 1500
             D ++ +   +  +  D+ SD  E  +      DSSD+S+  DD
Sbjct: 230  DDSDVPDDSSDDSEAPDDSSDDSEAPD------DSSDDSEAPDD 267



 Score = 48.1 bits (113), Expect = 6e-05
 Identities = 26/112 (23%), Positives = 54/112 (48%), Gaps = 6/112 (5%)

Query: 1395 AEDEDEEEDQEEEEQEEEDDDEDD------DDTDDLDELDTDQLLEAELEEDDNNENAGE 1448
            +E  D+  D  +   +  DD  DD      DD  D  ++  D+  ++++ +D ++++   
Sbjct: 176  SEAPDDNSDDSDVPDDNSDDSSDDNSDDSSDDNSDDSDVPDDKSDDSDVPDDSSDDSDVP 235

Query: 1449 DGDNDFSPSDEELANLLEEGEDGEDEDSDADEEVELILGDTDSSDNSDLEDD 1500
            D  +D S + ++ ++  E  +D  D+    D+  +      DSSD+S+  DD
Sbjct: 236  DDSSDDSEAPDDSSDDSEAPDDSSDDSEAPDDSSDDSEAPDDSSDDSEASDD 287



 Score = 45.4 bits (106), Expect = 4e-04
 Identities = 27/105 (25%), Positives = 49/105 (46%), Gaps = 2/105 (1%)

Query: 1395 AEDEDEEEDQEEEEQEEEDDDEDDDDTDDLDELDTDQLLEAELEEDDNNENAGEDGDNDF 1454
            +E  D+  D  E   +  DD E  DD+ D  E   D+  ++++ ED ++++   D ++D 
Sbjct: 272  SEAPDDSSDDSEASDDSSDDSEASDDSSDDSEAPDDKSDDSDVPEDKSDDSDVPDDNSDD 331

Query: 1455 SPSDEELANLLEEGEDGEDEDSDADEEVELILGDTDSSDNSDLED 1499
                    +L  EG+   DE+     E    +   DSSD++  +D
Sbjct: 332  LEVPVPAEDLCNEGQIASDEEELV--EAAAAVSQHDSSDDAGEQD 374



 Score = 44.7 bits (104), Expect = 7e-04
 Identities = 25/106 (23%), Positives = 53/106 (50%), Gaps = 11/106 (10%)

Query: 1395 AEDEDEEEDQEEEEQEEEDDDEDDDDTDDLDELDTDQLLEAELEEDDNNENAGEDGDNDF 1454
            ++D +  +D  ++ +  +D+ +D D  DD  +  +D         DD++++  +D D   
Sbjct: 163  SDDSEAPDDNSDDSEAPDDNSDDSDVPDDNSDDSSDD------NSDDSSDDNSDDSDVPD 216

Query: 1455 SPSDEELANLLEEGEDGEDEDSDADEEVELILGDTDSSDNSDLEDD 1500
              SD+  +++ ++  D  D   D+ ++ E      DSSD+S+  DD
Sbjct: 217  DKSDD--SDVPDDSSDDSDVPDDSSDDSE---APDDSSDDSEAPDD 257



 Score = 43.1 bits (100), Expect = 0.002
 Identities = 34/129 (26%), Positives = 56/129 (43%), Gaps = 30/129 (23%)

Query: 1381 DTVCRLYEVGRQRLAEDEDEEEDQE---------EEEQEEEDDDEDDDDTDDLDELDTDQ 1431
            D  C  +E  + +L E   ++E  E         E      DDD DDD+ +DL+  D   
Sbjct: 84   DEECHTHEEKKAKLLEINSDDESPECCHVKPAIQEPPIVISDDDNDDDNGNDLEVPD--- 140

Query: 1432 LLEAELEEDDNNENAGEDGDNDFSPSDEELANLLEEGEDGEDEDSDADEEVELILGDTDS 1491
                  +  D++E   ++ D+  +P D    +   E  D   +DS+A +         D+
Sbjct: 141  ------DNSDDSEAPDDNSDDSEAPDDNSDDS---EAPDDNSDDSEAPD---------DN 182

Query: 1492 SDNSDLEDD 1500
            SD+SD+ DD
Sbjct: 183  SDDSDVPDD 191


>gi|42740903 MTERF domain containing 2 [Homo sapiens]
          Length = 381

 Score = 53.1 bits (126), Expect = 2e-06
 Identities = 26/75 (34%), Positives = 44/75 (58%), Gaps = 7/75 (9%)

Query: 1387 YEVGRQRLAEDEDEEEDQEEEEQEEE-DDDEDDDDTDDLDELDTDQLLEAELEEDDNNEN 1445
            ++V ++ LA +E+E E    +++    D+DEDDDD +D DE D D+      ++DD +++
Sbjct: 313  FQVFKKLLAREEEESESSTSDDKRASLDEDEDDDDEEDNDEDDNDE------DDDDEDDD 366

Query: 1446 AGEDGDNDFSPSDEE 1460
              ED D D    +EE
Sbjct: 367  EAEDNDEDEDDDEEE 381



 Score = 42.0 bits (97), Expect = 0.004
 Identities = 27/74 (36%), Positives = 36/74 (48%), Gaps = 16/74 (21%)

Query: 1408 EQEEEDDDEDDDDTDDLDELDTDQLLEAELEEDDNNENAGEDGDNDFSPSDEELANLLEE 1467
            E+EE +    DD    LDE           +EDD++E   ++ DND    DE+     +E
Sbjct: 323  EEEESESSTSDDKRASLDE-----------DEDDDDEEDNDEDDNDEDDDDED----DDE 367

Query: 1468 GEDGEDEDSDADEE 1481
             ED  DED D DEE
Sbjct: 368  AED-NDEDEDDDEE 380



 Score = 38.5 bits (88), Expect = 0.050
 Identities = 19/55 (34%), Positives = 35/55 (63%), Gaps = 4/55 (7%)

Query: 1446 AGEDGDNDFSPSDEELANLLEEGEDGEDEDSDADEEVELILGDTDSSDNSDLEDD 1500
            A E+ +++ S SD++ A+L E+ +D ++ED+D D+  E    D D  D+ + ED+
Sbjct: 321  AREEEESESSTSDDKRASLDEDEDDDDEEDNDEDDNDE----DDDDEDDDEAEDN 371



 Score = 33.1 bits (74), Expect = 2.1
 Identities = 21/70 (30%), Positives = 34/70 (48%), Gaps = 10/70 (14%)

Query: 1431 QLLEAELEEDDNNENAGEDGDNDFSPSDEELANLLEEGEDGEDEDSDADEEVELILGDTD 1490
            +LL  E EE +++ +  +    D    D++     EE  D +D D D D+E      D +
Sbjct: 318  KLLAREEEESESSTSDDKRASLDEDEDDDD-----EEDNDEDDNDEDDDDE-----DDDE 367

Query: 1491 SSDNSDLEDD 1500
            + DN + EDD
Sbjct: 368  AEDNDEDEDD 377


>gi|86262149 zinc finger and BTB domain containing 7C [Homo sapiens]
          Length = 619

 Score = 53.1 bits (126), Expect = 2e-06
 Identities = 28/65 (43%), Positives = 39/65 (60%), Gaps = 3/65 (4%)

Query: 1396 EDEDEEEDQEEEEQEEEDDDEDDDDTDDLDELDTDQLL---EAELEEDDNNENAGEDGDN 1452
            ED+D+EED+EEEE+EEEDDD+D +D  D + L   Q +   ++  + D   E A  D   
Sbjct: 146  EDDDDEEDEEEEEEEEEDDDDDTEDFADQENLPDPQDISCHQSPSKTDHLTEKAYSDTPR 205

Query: 1453 DFSPS 1457
            DF  S
Sbjct: 206  DFPDS 210



 Score = 42.7 bits (99), Expect = 0.003
 Identities = 22/79 (27%), Positives = 42/79 (53%), Gaps = 4/79 (5%)

Query: 1397 DEDEEEDQEEEEQEEEDDDEDDDDTDDLDELDTDQLLEAELEEDDNNENAGEDGDNDFSP 1456
            D  EE+D+E+++ +E+DDDE+D++ ++ +E D D     + E+  + EN  +  D     
Sbjct: 132  DGGEEDDKEDDDDDEDDDDEEDEEEEEEEEEDDDD----DTEDFADQENLPDPQDISCHQ 187

Query: 1457 SDEELANLLEEGEDGEDED 1475
            S  +  +L E+       D
Sbjct: 188  SPSKTDHLTEKAYSDTPRD 206



 Score = 40.0 bits (92), Expect = 0.017
 Identities = 18/55 (32%), Positives = 36/55 (65%), Gaps = 2/55 (3%)

Query: 1383 VC-RLYEVGRQRLAEDEDEEEDQEEEEQEEEDDDEDDDDTDDLDELDTDQLLEAE 1436
            VC  + E G     ED+ E++D +E++ +EED++E++++ +D D+ DT+   + E
Sbjct: 122  VCLEIMEPGGDGGEEDDKEDDDDDEDDDDEEDEEEEEEEEED-DDDDTEDFADQE 175



 Score = 32.0 bits (71), Expect = 4.6
 Identities = 23/68 (33%), Positives = 32/68 (47%), Gaps = 12/68 (17%)

Query: 1440 DDNNENAGEDGDNDFSPSDEELANLLEEGEDGEDEDSDADEEVELILGDTDSSDNSDLED 1499
            D   E+  ED D+D    DEE     EE E+ E+ED D D E        D +D  +L D
Sbjct: 132  DGGEEDDKEDDDDDEDDDDEED----EEEEEEEEEDDDDDTE--------DFADQENLPD 179

Query: 1500 DIILSLNE 1507
               +S ++
Sbjct: 180  PQDISCHQ 187


>gi|42476169 Paf1, RNA polymerase II associated factor, homolog [Homo
            sapiens]
          Length = 531

 Score = 53.1 bits (126), Expect = 2e-06
 Identities = 31/102 (30%), Positives = 54/102 (52%), Gaps = 4/102 (3%)

Query: 1399 DEEEDQEEEEQEEEDDDEDDDDTDDLDELDTDQLLEAELEEDDNNENAGEDGDNDFSPSD 1458
            +  E +EEEE+E E ++++   +D+  E  +    E   +E   +E+  E+GD D   SD
Sbjct: 372  ENHEPEEEEEEEMETEEKEAGGSDEEQEKGSSSEKEGSEDEHSGSESEREEGDRD-EASD 430

Query: 1459 EELANLLEEGEDGEDEDSDADEEVELILGDTDSSDNSDLEDD 1500
            +  +    E E  EDE   A ++ E+   D DS D++D +D+
Sbjct: 431  KSGSG---EDESSEDEARAARDKEEIFGSDADSEDDADSDDE 469



 Score = 33.9 bits (76), Expect = 1.2
 Identities = 27/88 (30%), Positives = 38/88 (43%), Gaps = 11/88 (12%)

Query: 1395 AEDEDEEEDQEEEEQEEEDDDED---DDDTDDLDELDTDQLLEAELEEDDNNENAGEDGD 1451
            +E E  E++    E E E+ D D   D      DE   D+   A     D  E  G D D
Sbjct: 404  SEKEGSEDEHSGSESEREEGDRDEASDKSGSGEDESSEDEARAAR----DKEEIFGSDAD 459

Query: 1452 N-DFSPSDEELANLLEEGEDGEDEDSDA 1478
            + D + SD+E      + + G D DSD+
Sbjct: 460  SEDDADSDDEDRG---QAQGGSDNDSDS 484



 Score = 33.5 bits (75), Expect = 1.6
 Identities = 24/94 (25%), Positives = 36/94 (38%), Gaps = 8/94 (8%)

Query: 1396 EDEDEEEDQEEEEQEEE--DDDEDDDDTDDLDELDTDQLLEAELEEDDNNENAGEDGDND 1453
            EDE  E++      +EE    D D +D  D D+ D  Q       + D+  N G      
Sbjct: 436  EDESSEDEARAARDKEEIFGSDADSEDDADSDDEDRGQAQGGSDNDSDSGSNGGGQRSRS 495

Query: 1454 FS------PSDEELANLLEEGEDGEDEDSDADEE 1481
             S      PS  E +   +  E    + S+AD +
Sbjct: 496  HSRSASPFPSGSEHSAQEDGSEAAASDSSEADSD 529


>gi|195546900 suppressor of Ty 5 homolog isoform a [Homo sapiens]
          Length = 1087

 Score = 52.8 bits (125), Expect = 3e-06
 Identities = 31/87 (35%), Positives = 50/87 (57%), Gaps = 5/87 (5%)

Query: 1390 GRQRLAEDEDEEEDQEEEEQEEEDDDEDDDDTDDLDELDTDQLLEAELEEDDNNENAGED 1449
            G ++  E EDEEE++EEEE +EE+++EDDD            L EA+++++  +E+  ED
Sbjct: 35   GSEKEEEPEDEEEEEEEEEYDEEEEEEDDDRPPKKPRHGGFILDEADVDDEYEDEDQWED 94

Query: 1450 GDNDFSPSDE-ELANL----LEEGEDG 1471
            G  D    +E E +N+    L+E   G
Sbjct: 95   GAEDILEKEEIEASNIDNVVLDEDRSG 121



 Score = 47.4 bits (111), Expect = 1e-04
 Identities = 37/138 (26%), Positives = 61/138 (44%), Gaps = 24/138 (17%)

Query: 1388 EVGRQRLAEDEDEEEDQEEEEQEEEDDDEDDDDTDD-------------LDELDTDQLLE 1434
            E  R     +++EE + EEEE+EEE+ DE++++ DD             LDE D D   E
Sbjct: 28   EERRSAAGSEKEEEPEDEEEEEEEEEYDEEEEEEDDDRPPKKPRHGGFILDEADVDDEYE 87

Query: 1435 AELEEDDNNENAGEDGDNDFSPSD-----------EELANLLEEGEDGEDEDSDADEEVE 1483
             E + +D  E+  E  + + S  D             L NL  +  + E  +    +  +
Sbjct: 88   DEDQWEDGAEDILEKEEIEASNIDNVVLDEDRSGARRLQNLWRDQREEELGEYYMKKYAK 147

Query: 1484 LILGDTDSSDNSDLEDDI 1501
              +G+T    + +L DDI
Sbjct: 148  SSVGETVYGGSDELSDDI 165



 Score = 37.0 bits (84), Expect = 0.14
 Identities = 29/120 (24%), Positives = 60/120 (50%), Gaps = 20/120 (16%)

Query: 1388 EVGRQRLAEDEDEEEDQE-------EEEQEEEDDDEDDDDTDDLDELDTDQLLEAELEED 1440
            E   +R ++ E+ E D+E       E+E+E ED++E++++ ++ DE         E EE+
Sbjct: 12   EEDSERSSDGEEAEVDEERRSAAGSEKEEEPEDEEEEEEE-EEYDE---------EEEEE 61

Query: 1441 DNNENAGEDGDNDFSPSDEELANLLEEGEDGEDEDSDADEEVELILGDTDSSDNSDLEDD 1500
            D++    +     F   + ++ +  E+ +  ED   D  E+ E+   +  + DN  L++D
Sbjct: 62   DDDRPPKKPRHGGFILDEADVDDEYEDEDQWEDGAEDILEKEEI---EASNIDNVVLDED 118



 Score = 36.6 bits (83), Expect = 0.19
 Identities = 26/118 (22%), Positives = 53/118 (44%), Gaps = 11/118 (9%)

Query: 1394 LAEDEDEEEDQEEEEQEEEDDDEDDDDTDDLDELDTDQLLEAELEEDDNNENA----GED 1449
            +++ ED    +EE+ +   D +E + D +      +++  E E EE++  E       E+
Sbjct: 1    MSDSEDSNFSEEEDSERSSDGEEAEVDEERRSAAGSEKEEEPEDEEEEEEEEEYDEEEEE 60

Query: 1450 GDNDFSPSDEELANLLEEGEDGEDEDSDADEEVELILGDTDSSDNSDLE----DDIIL 1503
             D+D  P        + +  D +DE  D D+  +   G  D  +  ++E    D+++L
Sbjct: 61   EDDDRPPKKPRHGGFILDEADVDDEYEDEDQWED---GAEDILEKEEIEASNIDNVVL 115


>gi|161169023 suppressor of Ty 5 homolog isoform a [Homo sapiens]
          Length = 1087

 Score = 52.8 bits (125), Expect = 3e-06
 Identities = 31/87 (35%), Positives = 50/87 (57%), Gaps = 5/87 (5%)

Query: 1390 GRQRLAEDEDEEEDQEEEEQEEEDDDEDDDDTDDLDELDTDQLLEAELEEDDNNENAGED 1449
            G ++  E EDEEE++EEEE +EE+++EDDD            L EA+++++  +E+  ED
Sbjct: 35   GSEKEEEPEDEEEEEEEEEYDEEEEEEDDDRPPKKPRHGGFILDEADVDDEYEDEDQWED 94

Query: 1450 GDNDFSPSDE-ELANL----LEEGEDG 1471
            G  D    +E E +N+    L+E   G
Sbjct: 95   GAEDILEKEEIEASNIDNVVLDEDRSG 121



 Score = 47.4 bits (111), Expect = 1e-04
 Identities = 37/138 (26%), Positives = 61/138 (44%), Gaps = 24/138 (17%)

Query: 1388 EVGRQRLAEDEDEEEDQEEEEQEEEDDDEDDDDTDD-------------LDELDTDQLLE 1434
            E  R     +++EE + EEEE+EEE+ DE++++ DD             LDE D D   E
Sbjct: 28   EERRSAAGSEKEEEPEDEEEEEEEEEYDEEEEEEDDDRPPKKPRHGGFILDEADVDDEYE 87

Query: 1435 AELEEDDNNENAGEDGDNDFSPSD-----------EELANLLEEGEDGEDEDSDADEEVE 1483
             E + +D  E+  E  + + S  D             L NL  +  + E  +    +  +
Sbjct: 88   DEDQWEDGAEDILEKEEIEASNIDNVVLDEDRSGARRLQNLWRDQREEELGEYYMKKYAK 147

Query: 1484 LILGDTDSSDNSDLEDDI 1501
              +G+T    + +L DDI
Sbjct: 148  SSVGETVYGGSDELSDDI 165



 Score = 37.0 bits (84), Expect = 0.14
 Identities = 29/120 (24%), Positives = 60/120 (50%), Gaps = 20/120 (16%)

Query: 1388 EVGRQRLAEDEDEEEDQE-------EEEQEEEDDDEDDDDTDDLDELDTDQLLEAELEED 1440
            E   +R ++ E+ E D+E       E+E+E ED++E++++ ++ DE         E EE+
Sbjct: 12   EEDSERSSDGEEAEVDEERRSAAGSEKEEEPEDEEEEEEE-EEYDE---------EEEEE 61

Query: 1441 DNNENAGEDGDNDFSPSDEELANLLEEGEDGEDEDSDADEEVELILGDTDSSDNSDLEDD 1500
            D++    +     F   + ++ +  E+ +  ED   D  E+ E+   +  + DN  L++D
Sbjct: 62   DDDRPPKKPRHGGFILDEADVDDEYEDEDQWEDGAEDILEKEEI---EASNIDNVVLDED 118



 Score = 36.6 bits (83), Expect = 0.19
 Identities = 26/118 (22%), Positives = 53/118 (44%), Gaps = 11/118 (9%)

Query: 1394 LAEDEDEEEDQEEEEQEEEDDDEDDDDTDDLDELDTDQLLEAELEEDDNNENA----GED 1449
            +++ ED    +EE+ +   D +E + D +      +++  E E EE++  E       E+
Sbjct: 1    MSDSEDSNFSEEEDSERSSDGEEAEVDEERRSAAGSEKEEEPEDEEEEEEEEEYDEEEEE 60

Query: 1450 GDNDFSPSDEELANLLEEGEDGEDEDSDADEEVELILGDTDSSDNSDLE----DDIIL 1503
             D+D  P        + +  D +DE  D D+  +   G  D  +  ++E    D+++L
Sbjct: 61   EDDDRPPKKPRHGGFILDEADVDDEYEDEDQWED---GAEDILEKEEIEASNIDNVVL 115


>gi|20149524 suppressor of Ty 5 homolog isoform a [Homo sapiens]
          Length = 1087

 Score = 52.8 bits (125), Expect = 3e-06
 Identities = 31/87 (35%), Positives = 50/87 (57%), Gaps = 5/87 (5%)

Query: 1390 GRQRLAEDEDEEEDQEEEEQEEEDDDEDDDDTDDLDELDTDQLLEAELEEDDNNENAGED 1449
            G ++  E EDEEE++EEEE +EE+++EDDD            L EA+++++  +E+  ED
Sbjct: 35   GSEKEEEPEDEEEEEEEEEYDEEEEEEDDDRPPKKPRHGGFILDEADVDDEYEDEDQWED 94

Query: 1450 GDNDFSPSDE-ELANL----LEEGEDG 1471
            G  D    +E E +N+    L+E   G
Sbjct: 95   GAEDILEKEEIEASNIDNVVLDEDRSG 121



 Score = 47.4 bits (111), Expect = 1e-04
 Identities = 37/138 (26%), Positives = 61/138 (44%), Gaps = 24/138 (17%)

Query: 1388 EVGRQRLAEDEDEEEDQEEEEQEEEDDDEDDDDTDD-------------LDELDTDQLLE 1434
            E  R     +++EE + EEEE+EEE+ DE++++ DD             LDE D D   E
Sbjct: 28   EERRSAAGSEKEEEPEDEEEEEEEEEYDEEEEEEDDDRPPKKPRHGGFILDEADVDDEYE 87

Query: 1435 AELEEDDNNENAGEDGDNDFSPSD-----------EELANLLEEGEDGEDEDSDADEEVE 1483
             E + +D  E+  E  + + S  D             L NL  +  + E  +    +  +
Sbjct: 88   DEDQWEDGAEDILEKEEIEASNIDNVVLDEDRSGARRLQNLWRDQREEELGEYYMKKYAK 147

Query: 1484 LILGDTDSSDNSDLEDDI 1501
              +G+T    + +L DDI
Sbjct: 148  SSVGETVYGGSDELSDDI 165



 Score = 37.0 bits (84), Expect = 0.14
 Identities = 29/120 (24%), Positives = 60/120 (50%), Gaps = 20/120 (16%)

Query: 1388 EVGRQRLAEDEDEEEDQE-------EEEQEEEDDDEDDDDTDDLDELDTDQLLEAELEED 1440
            E   +R ++ E+ E D+E       E+E+E ED++E++++ ++ DE         E EE+
Sbjct: 12   EEDSERSSDGEEAEVDEERRSAAGSEKEEEPEDEEEEEEE-EEYDE---------EEEEE 61

Query: 1441 DNNENAGEDGDNDFSPSDEELANLLEEGEDGEDEDSDADEEVELILGDTDSSDNSDLEDD 1500
            D++    +     F   + ++ +  E+ +  ED   D  E+ E+   +  + DN  L++D
Sbjct: 62   DDDRPPKKPRHGGFILDEADVDDEYEDEDQWEDGAEDILEKEEI---EASNIDNVVLDED 118



 Score = 36.6 bits (83), Expect = 0.19
 Identities = 26/118 (22%), Positives = 53/118 (44%), Gaps = 11/118 (9%)

Query: 1394 LAEDEDEEEDQEEEEQEEEDDDEDDDDTDDLDELDTDQLLEAELEEDDNNENA----GED 1449
            +++ ED    +EE+ +   D +E + D +      +++  E E EE++  E       E+
Sbjct: 1    MSDSEDSNFSEEEDSERSSDGEEAEVDEERRSAAGSEKEEEPEDEEEEEEEEEYDEEEEE 60

Query: 1450 GDNDFSPSDEELANLLEEGEDGEDEDSDADEEVELILGDTDSSDNSDLE----DDIIL 1503
             D+D  P        + +  D +DE  D D+  +   G  D  +  ++E    D+++L
Sbjct: 61   EDDDRPPKKPRHGGFILDEADVDDEYEDEDQWED---GAEDILEKEEIEASNIDNVVL 115


>gi|210147569 acidic (leucine-rich) nuclear phosphoprotein 32 family,
            member E isoform 2 [Homo sapiens]
          Length = 227

 Score = 52.8 bits (125), Expect = 3e-06
 Identities = 35/120 (29%), Positives = 64/120 (53%), Gaps = 16/120 (13%)

Query: 1397 DEDEEEDQEEEEQEEEDDDEDDDDTDDLDELDTDQLLEAELEEDDNNENAGEDGD---ND 1453
            D+++ E  + EE+++ED DEDD++ ++ +    +   E E EE++ +E+  ED D   ++
Sbjct: 108  DQEDNEAPDSEEEDDEDGDEDDEEEEENEAGPPEGYEEEEEEEEEEDEDEDEDEDEAGSE 167

Query: 1454 FSPSDEELA---NLLEEGEDGEDED---SDADEEVELILG-------DTDSSDNSDLEDD 1500
                +EE+     + EE +D ED+D    + +EE E   G         D+ D+ + EDD
Sbjct: 168  LGEGEEEVGLSYLMKEEIQDEEDDDDYVEEGEEEEEEEEGGLRGEKRKRDAEDDGEEEDD 227



 Score = 50.1 bits (118), Expect = 2e-05
 Identities = 25/94 (26%), Positives = 57/94 (60%), Gaps = 9/94 (9%)

Query: 1388 EVGRQRLAEDEDEEEDQEEEEQEEEDDDEDDDDTDDLDELDTDQLLEAELEEDDNNENAG 1447
            E G     E+E+EEE++E+E+++E++D+   +  +  +E+    L++ E+++++++++  
Sbjct: 136  EAGPPEGYEEEEEEEEEEDEDEDEDEDEAGSELGEGEEEVGLSYLMKEEIQDEEDDDDYV 195

Query: 1448 EDGDNDFSPSDEELANLLEE------GEDGEDED 1475
            E+G+ +    +EE   L  E       +DGE+ED
Sbjct: 196  EEGEEE---EEEEEGGLRGEKRKRDAEDDGEEED 226



 Score = 34.3 bits (77), Expect = 0.93
 Identities = 34/142 (23%), Positives = 61/142 (42%), Gaps = 40/142 (28%)

Query: 1369 IENQGSMDALNMDTVC------RLYEVGRQRLAEDEDEEEDQEEEEQEEEDDDEDDDDTD 1422
            ++N  S+D  N +          ++E+ +Q    D  ++ED E  + EEEDD++ D+D  
Sbjct: 71   LKNLKSLDLFNCEITNLEDYRESIFELLQQITYLDGFDQEDNEAPDSEEEDDEDGDEDD- 129

Query: 1423 DLDELDTDQLLEAELEEDDNNENAGEDGDNDFSPSDEELANLLEEGEDGEDEDSDADEEV 1482
                           EE++ NE AG                   EG + E+E+ + ++E 
Sbjct: 130  ---------------EEEEENE-AGPP-----------------EGYEEEEEEEEEEDED 156

Query: 1483 ELILGDTDSSDNSDLEDDIILS 1504
            E    D   S+  + E+++ LS
Sbjct: 157  EDEDEDEAGSELGEGEEEVGLS 178


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.318    0.134    0.393 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 59,385,173
Number of Sequences: 37866
Number of extensions: 2994723
Number of successful extensions: 49524
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 549
Number of HSP's successfully gapped in prelim test: 373
Number of HSP's that attempted gapping in prelim test: 24247
Number of HSP's gapped (non-prelim): 11011
length of query: 1507
length of database: 18,247,518
effective HSP length: 115
effective length of query: 1392
effective length of database: 13,892,928
effective search space: 19338955776
effective search space used: 19338955776
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 69 (31.2 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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