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Search of human proteins with 7657232
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|7657232 interleukin 1 receptor accessory protein-like 1
precursor [Homo sapiens]
(696 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|7657232 interleukin 1 receptor accessory protein-like 1 precu... 1422 0.0
gi|11225607 interleukin 1 receptor accessory protein-like 2 [Hom... 870 0.0
gi|4504661 interleukin 1 receptor accessory protein isoform 1 [H... 303 4e-82
gi|4504655 interleukin 18 receptor 1 precursor [Homo sapiens] 204 3e-52
gi|4504659 interleukin 1 receptor, type I precursor [Homo sapiens] 194 2e-49
gi|4504657 interleukin 18 receptor accessory protein precursor [... 194 2e-49
gi|28416902 interleukin 1 receptor-like 2 precursor [Homo sapiens] 165 2e-40
gi|27894324 interleukin 1 receptor-like 1 isoform 1 precursor [H... 162 1e-39
gi|19882209 interleukin 1 receptor accessory protein isoform 2 [... 154 3e-37
gi|27894334 interleukin 1 receptor, type II precursor [Homo sapi... 107 5e-23
gi|4758598 interleukin 1 receptor, type II precursor [Homo sapiens] 107 5e-23
gi|205277451 single Ig IL-1R-related molecule [Homo sapiens] 89 1e-17
gi|205277449 single Ig IL-1R-related molecule [Homo sapiens] 89 1e-17
gi|205277445 single Ig IL-1R-related molecule [Homo sapiens] 89 1e-17
gi|27894328 interleukin 1 receptor-like 1 isoform 2 precursor [H... 76 1e-13
gi|54607118 leucine-rich repeats and immunoglobulin-like domains... 58 3e-08
gi|41350337 toll-like receptor 1 [Homo sapiens] 57 4e-08
gi|20143971 toll-like receptor 6 [Homo sapiens] 52 2e-06
gi|116008194 myosin light chain kinase isoform 3A [Homo sapiens] 50 5e-06
gi|116008192 myosin light chain kinase isoform 1 [Homo sapiens] 50 5e-06
gi|116008190 myosin light chain kinase isoform 3B [Homo sapiens] 50 5e-06
gi|116008188 myosin light chain kinase isoform 2 [Homo sapiens] 50 5e-06
gi|193083163 roundabout, axon guidance receptor, homolog 2 isofo... 50 5e-06
gi|61888896 roundabout, axon guidance receptor, homolog 2 isofor... 50 5e-06
gi|19743806 roundabout 1 isoform b [Homo sapiens] 50 9e-06
gi|239755187 PREDICTED: similar to hemicentin 2 [Homo sapiens] 50 9e-06
gi|239749684 PREDICTED: hemicentin 2 [Homo sapiens] 50 9e-06
gi|239743951 PREDICTED: hypothetical protein XP_002342997 [Homo ... 50 9e-06
gi|4506569 roundabout 1 isoform a [Homo sapiens] 50 9e-06
gi|126517478 peroxidasin homolog-like [Homo sapiens] 50 9e-06
>gi|7657232 interleukin 1 receptor accessory protein-like 1
precursor [Homo sapiens]
Length = 696
Score = 1422 bits (3682), Expect = 0.0
Identities = 696/696 (100%), Positives = 696/696 (100%)
Query: 1 MKAPIPHLILLYATFTQSLKVVTKRGSADGCTDWSIDIKKYQVLVGEPVRIKCALFYGYI 60
MKAPIPHLILLYATFTQSLKVVTKRGSADGCTDWSIDIKKYQVLVGEPVRIKCALFYGYI
Sbjct: 1 MKAPIPHLILLYATFTQSLKVVTKRGSADGCTDWSIDIKKYQVLVGEPVRIKCALFYGYI 60
Query: 61 RTNYSLAQSAGLSLMWYKSSGPGDFEEPIAFDGSRMSKEEDSIWFRPTLLQDSGLYACVI 120
RTNYSLAQSAGLSLMWYKSSGPGDFEEPIAFDGSRMSKEEDSIWFRPTLLQDSGLYACVI
Sbjct: 61 RTNYSLAQSAGLSLMWYKSSGPGDFEEPIAFDGSRMSKEEDSIWFRPTLLQDSGLYACVI 120
Query: 121 RNSTYCMKVSISLTVGENDTGLCYNSKMKYFEKAELSKSKEISCRDIEDFLLPTREPEIL 180
RNSTYCMKVSISLTVGENDTGLCYNSKMKYFEKAELSKSKEISCRDIEDFLLPTREPEIL
Sbjct: 121 RNSTYCMKVSISLTVGENDTGLCYNSKMKYFEKAELSKSKEISCRDIEDFLLPTREPEIL 180
Query: 181 WYKECRTKTWRPSIVFKRDTLLIREVREDDIGNYTCELKYGGFVVRRTTELTVTAPLTDK 240
WYKECRTKTWRPSIVFKRDTLLIREVREDDIGNYTCELKYGGFVVRRTTELTVTAPLTDK
Sbjct: 181 WYKECRTKTWRPSIVFKRDTLLIREVREDDIGNYTCELKYGGFVVRRTTELTVTAPLTDK 240
Query: 241 PPKLLYPMESKLTIQETQLGDSANLTCRAFFGYSGDVSPLIYWMKGEKFIEDLDENRVWE 300
PPKLLYPMESKLTIQETQLGDSANLTCRAFFGYSGDVSPLIYWMKGEKFIEDLDENRVWE
Sbjct: 241 PPKLLYPMESKLTIQETQLGDSANLTCRAFFGYSGDVSPLIYWMKGEKFIEDLDENRVWE 300
Query: 301 SDIRILKEHLGEQEVSISLIVDSVEEGDLGNYSCYVENGNGRRHASVLLHKRELMYTVEL 360
SDIRILKEHLGEQEVSISLIVDSVEEGDLGNYSCYVENGNGRRHASVLLHKRELMYTVEL
Sbjct: 301 SDIRILKEHLGEQEVSISLIVDSVEEGDLGNYSCYVENGNGRRHASVLLHKRELMYTVEL 360
Query: 361 AGGLGAILLLLVCLVTIYKCYKIEIMLFYRNHFGAEELDGDNKDYDAYLSYTKVDPDQWN 420
AGGLGAILLLLVCLVTIYKCYKIEIMLFYRNHFGAEELDGDNKDYDAYLSYTKVDPDQWN
Sbjct: 361 AGGLGAILLLLVCLVTIYKCYKIEIMLFYRNHFGAEELDGDNKDYDAYLSYTKVDPDQWN 420
Query: 421 QETGEEERFALEILPDMLEKHYGYKLFIPDRDLIPTGTYIEDVARCVDQSKRLIIVMTPN 480
QETGEEERFALEILPDMLEKHYGYKLFIPDRDLIPTGTYIEDVARCVDQSKRLIIVMTPN
Sbjct: 421 QETGEEERFALEILPDMLEKHYGYKLFIPDRDLIPTGTYIEDVARCVDQSKRLIIVMTPN 480
Query: 481 YVVRRGWSIFELETRLRNMLVTGEIKVILIECSELRGIMNYQEVEALKHTIKLLTVIKWH 540
YVVRRGWSIFELETRLRNMLVTGEIKVILIECSELRGIMNYQEVEALKHTIKLLTVIKWH
Sbjct: 481 YVVRRGWSIFELETRLRNMLVTGEIKVILIECSELRGIMNYQEVEALKHTIKLLTVIKWH 540
Query: 541 GPKCNKLNSKFWKRLQYEMPFKRIEPITHEQALDVSEQGPFGELQTVSAISMAAATSTAL 600
GPKCNKLNSKFWKRLQYEMPFKRIEPITHEQALDVSEQGPFGELQTVSAISMAAATSTAL
Sbjct: 541 GPKCNKLNSKFWKRLQYEMPFKRIEPITHEQALDVSEQGPFGELQTVSAISMAAATSTAL 600
Query: 601 ATAHPDLRSTFHNTYHSQMRQKHYYRSYEYDVPPTGTLPLTSIGNQHTYCNIPMTLINGQ 660
ATAHPDLRSTFHNTYHSQMRQKHYYRSYEYDVPPTGTLPLTSIGNQHTYCNIPMTLINGQ
Sbjct: 601 ATAHPDLRSTFHNTYHSQMRQKHYYRSYEYDVPPTGTLPLTSIGNQHTYCNIPMTLINGQ 660
Query: 661 RPQTKSSREQNPDEAHTNSAILPLLPRETSISSVIW 696
RPQTKSSREQNPDEAHTNSAILPLLPRETSISSVIW
Sbjct: 661 RPQTKSSREQNPDEAHTNSAILPLLPRETSISSVIW 696
>gi|11225607 interleukin 1 receptor accessory protein-like 2 [Homo
sapiens]
Length = 686
Score = 870 bits (2248), Expect = 0.0
Identities = 426/696 (61%), Positives = 542/696 (77%), Gaps = 10/696 (1%)
Query: 1 MKAPIPHLILLYATFTQSLKVVTKRGSADGCTDWSIDIKKYQVLVGEPVRIKCALFYGYI 60
MK P +++ + + +LK+V+KR S DGC DWS+D+K Y L GEPVR+KCALFY YI
Sbjct: 1 MKPPFLLALVVCSVVSTNLKMVSKRNSVDGCIDWSVDLKTYMALAGEPVRVKCALFYSYI 60
Query: 61 RTNYSLAQSAGLSLMWYKSSGPGDFEEPIAFDGSRMSKEEDSIWFRPTLLQDSGLYACVI 120
RTNYS AQS GL LMWYK+ G D EEPI F RMSKEEDSIWF QDSG Y CV+
Sbjct: 61 RTNYSTAQSTGLRLMWYKNKG--DLEEPIIFSEVRMSKEEDSIWFHSAEAQDSGFYTCVL 118
Query: 121 RNSTYCMKVSISLTVGENDTGLCYNSKMKYFEKAELSKSKEISCRDIEDFLLPTREPEIL 180
RNSTYCMKVS+SLTV EN++GLCYNS+++Y EK+E++K KEISC D++DF +EP+++
Sbjct: 119 RNSTYCMKVSMSLTVAENESGLCYNSRIRYLEKSEVTKRKEISCPDMDDFKKSDQEPDVV 178
Query: 181 WYKECRTKTWRPSIVFKRDTLLIREVREDDIGNYTCELKYGGFVVRRTTELTVTAPLTDK 240
WYKEC+ K WR I+ K + LLI+EV+E+D GNYTCELKY G +VRRTTEL VTA LTDK
Sbjct: 179 WYKECKPKMWRSIIIQKGNALLIQEVQEEDGGNYTCELKYEGKLVRRTTELKVTALLTDK 238
Query: 241 PPKLLYPMESKLTIQETQLGDSANLTCRAFFGYSGDVSPLIYWMKGEKFIEDLDENRVWE 300
PPK L+PME++ ++ + QLG N+ C+AFFG+SG+ P+IYWMKGEKFIE+L + E
Sbjct: 239 PPKPLFPMENQPSVIDVQLGKPLNIPCKAFFGFSGESGPMIYWMKGEKFIEEL-AGHIRE 297
Query: 301 SDIRILKEHLGEQEVSISLIVDSVEEGDLGNYSCYVENGNGRRHASVLLHKRELMYTVEL 360
+IR+LKEHLGE+EV ++LI DSV E DL NY+C+VEN NGR+HASVLL K++L+Y +EL
Sbjct: 298 GEIRLLKEHLGEKEVELALIFDSVVEADLANYTCHVENRNGRKHASVLLRKKDLIYKIEL 357
Query: 361 AGGLGAILLLLVCLVTIYKCYKIEIMLFYRNHFGAEELDGDNKDYDAYLSYTKVDPDQWN 420
AGGLGAI LLLV LV IYKCY IE+MLFYR HFGA+E + DNK+YDAYLSYTKVD D +
Sbjct: 358 AGGLGAIFLLLVLLVVIYKCYNIELMLFYRQHFGADETNDDNKEYDAYLSYTKVDQDTLD 417
Query: 421 QETGEEERFALEILPDMLEKHYGYKLFIPDRDLIPTGTYIEDVARCVDQSKRLIIVMTPN 480
+ EEE+FALE+LPD+LEKHYGYKLFIP+RDLIP+GTY+ED+ R V+QS+RLIIV+TP+
Sbjct: 418 CDNPEEEQFALEVLPDVLEKHYGYKLFIPERDLIPSGTYMEDLTRYVEQSRRLIIVLTPD 477
Query: 481 YVVRRGWSIFELETRLRNMLVTGEIKVILIECSELRGIMNYQEVEALKHTIKLLTVIKWH 540
Y++RRGWSIFELE+RL NMLV+GEIKVILIEC+EL+G +N QEVE+LK +IKLL++IKW
Sbjct: 478 YILRRGWSIFELESRLHNMLVSGEIKVILIECTELKGKVNCQEVESLKRSIKLLSLIKWK 537
Query: 541 GPKCNKLNSKFWKRLQYEMPFKRIEPITHEQALDVSEQGPFGELQTVSAISMAAATSTAL 600
G K +KLNSKFWK L YEMP K+ E + LD +EQG FGELQ + +I+M +TS L
Sbjct: 538 GSKSSKLNSKFWKHLVYEMPIKKKEMLPRCHVLDSAEQGLFGELQPIPSIAM-TSTSATL 596
Query: 601 ATAHPDLRSTFHNTYHSQMRQKHYYRSYEYDVPPTGTLPLTSIGNQHTYCNIPMTLINGQ 660
++ DL FH + Q+R H R Y++++P T TLP+ S+GN HTYCN+P+TL+NGQ
Sbjct: 597 VSSQADL-PEFHPSDSMQIR--HCCRGYKHEIPAT-TLPVPSLGNHHTYCNLPLTLLNGQ 652
Query: 661 RPQTKSSREQNPDEAHTNSAILPLLPRETSISSVIW 696
P + ++ E H NS++LPL +E S +S IW
Sbjct: 653 LPLNNTLKD--TQEFHRNSSLLPLSSKELSFTSDIW 686
>gi|4504661 interleukin 1 receptor accessory protein isoform 1 [Homo
sapiens]
Length = 570
Score = 303 bits (776), Expect = 4e-82
Identities = 192/568 (33%), Positives = 294/568 (51%), Gaps = 30/568 (5%)
Query: 8 LILLYATFTQSLKVVTKRGSADGCTDWSID-IKKYQVLVGEPVRIKCALFYGYIRTNYSL 66
+ LL+ + + + +++ C DW +D +++ QV EP RIKC LF +++ NYS
Sbjct: 1 MTLLWCVVSLYFYGILQSDASERCDDWGLDTMRQIQVFEDEPARIKCPLFEHFLKFNYST 60
Query: 67 AQSAGLSLMWYKSSGPGDFEEPIAF--DGSRMSKEEDSIWFRPTLLQDSGLYACVIRNST 124
A SAGL+L+WY + D EEPI F +R+SKE+D +WFRPTLL D+G Y C++RN+T
Sbjct: 61 AHSAGLTLIWYWTRQDRDLEEPINFRLPENRISKEKDVLWFRPTLLNDTGNYTCMLRNTT 120
Query: 125 YCMKVSISLTVGENDTGLCYNSKMKY-FEKAELSKS-KEISCRDIEDFLLPTREPEILWY 182
YC KV+ L V + D+ C+NS MK K + + I+C +++ + + +P I WY
Sbjct: 121 YCSKVAFPLEVVQKDS--CFNSPMKLPVHKLYIEYGIQRITCPNVDGYFPSSVKPTITWY 178
Query: 183 KECRTKTWRPSIVFKRDTLLIREVREDDIGNYTCELKY--GGFVVRRTTELTVT---APL 237
C +++ + L + GNYTC + Y G T LTV +P
Sbjct: 179 MGCYKIQNFNNVIPEGMNLSFLIALISNNGNYTCVVTYPENGRTFHLTRTLTVKVVGSPK 238
Query: 238 TDKPPKLLYPMESKLTIQETQLGDSANLTCRAFFGYSGDVSPLIYWMKGEKFIEDLDENR 297
PP + P + + E + G+ + C +F + D ++W K +D+ +
Sbjct: 239 NAVPPVIHSPNDH--VVYEKEPGEELLIPCTVYFSFLMDSRNEVWWTIDGKKPDDITIDV 296
Query: 298 VWESDIRILKEHLGEQEVSISLIVDSVEEGDLGNYSCYVENGNGR--RHASVLLHKRELM 355
I + E I I E +Y C+ + G + A V
Sbjct: 297 TINESISHSRTE-DETRTQILSIKKVTSEDLKRSYVCHARSAKGEVAKAAKVKQKVPAPR 355
Query: 356 YTVELAGGLGAILLLLVCLVTIYKCYKIEIMLFYRNHFGAEELDGDNKDYDAYLSYTKVD 415
YTVELA G GA +LL+V L+ +Y Y +E++LFYR HFG +E D K+YD Y+SY +
Sbjct: 356 YTVELACGFGATVLLVVILIVVYHVYWLEMVLFYRAHFGTDETILDGKEYDIYVSYAR-- 413
Query: 416 PDQWNQETGEEERFALEILPDMLEKHYGYKLFIPDRDLIPTGTYIEDVARCVDQSKRLII 475
EEE F L L +LE +GYKL I DRD +P G ++ + +S+RL++
Sbjct: 414 -------NAEEEEFVLLTLRGVLENEFGYKLCIFDRDSLPGGIVTDETLSFIQKSRRLLV 466
Query: 476 VMTPNYVVRRGWSIFELETRLRNMLVTGEIKVILIECSELRGIMNYQEVEALKHTIKLLT 535
V++PNYV++ ++ EL+ L NM G I VIL++ ++ +V+ LK +LT
Sbjct: 467 VLSPNYVLQGTQALLELKAGLENMASRGNINVILVQYKAVK----ETKVKELKRAKTVLT 522
Query: 536 VIKWHGPKCNKLNSKFWKRLQYEMPFKR 563
VIKW G K +FWK+LQ MP K+
Sbjct: 523 VIKWKGEKSKYPQGRFWKQLQVAMPVKK 550
>gi|4504655 interleukin 18 receptor 1 precursor [Homo sapiens]
Length = 541
Score = 204 bits (518), Expect = 3e-52
Identities = 171/566 (30%), Positives = 277/566 (48%), Gaps = 64/566 (11%)
Query: 18 SLKVVTKRGSADGCTDWSIDIKKYQVLVGEPVRIK---CALFYGYIRTNYSLAQSAGLSL 74
+L V+ +A+ CT V+ GEP +K C+L + T S
Sbjct: 9 TLWVLISVSTAESCTSRP----HITVVEGEPFYLKHCSCSLAHEIETTTKS--------- 55
Query: 75 MWYKSSGPGDFEEPIAFDGSRMSKEEDSIWFRPTLLQDSGLYACVIRNSTYCMKVSISLT 134
WYKSSG + E SR++ + + F P L D+G Y ++N T K L
Sbjct: 56 -WYKSSGSQEHVELNPRSSSRIALHDCVLEFWPVELNDTGSYFFQMKNYTQKWK----LN 110
Query: 135 VGENDTGLCYNSKMKYFEKAELSKSKEISCRDIEDFLLPTREPEILWYKECRTKTWRPSI 194
V + C+ + + E+ K +I+C E+ T YK C+ + +
Sbjct: 111 VIRRNKHSCFTERQVTSKIVEVKKFFQITC---ENSYYQTLVNSTSLYKNCK----KLLL 163
Query: 195 VFKRDTLLIREVREDDIGNYTCE--LKYGG--FVVRRTTELTVTAPLTDKPPKLLYPMES 250
++ + + +D G Y+C L + G F + +T +T+ ++ P LL P
Sbjct: 164 ENNKNPTIKKNAEFEDQGYYSCVHFLHHNGKLFNITKTFNITIVEDRSNIVPVLLGP--- 220
Query: 251 KLTIQETQLGDSANLTCRAFFGYSGDVSPLIYWMKGEKFIEDLDENRVWESDIRILKEHL 310
KL +LG + L C A + +IYWM GE+ D N E ++RI+
Sbjct: 221 KLNHVAVELGKNVRLNCSALL----NEEDVIYWMFGEE--NGSDPNIHEEKEMRIMTPE- 273
Query: 311 GEQEVSISLIVDSVEEGDLGN-YSCYVENGNGRRHASVLLHKRELMYTVE----LAGGLG 365
G+ S L ++++ E +L Y+C V + G S +L ++ M + G +
Sbjct: 274 GKWHASKVLRIENIGESNLNVLYNCTVASTGGTDTKSFILVRKADMADIPGHVFTRGMII 333
Query: 366 AILLLL--VCLVTIYKCYKIEIMLFYRNHFGAEELDGDNKDYDAYLSYTKVDPDQWNQET 423
A+L+L+ VCLVT+ Y+++++LFYR+ +E D K YDA++SY K + E
Sbjct: 334 AVLILVAVVCLVTVCVIYRVDLVLFYRHLTRRDETLTDGKTYDAFVSYLK----ECRPEN 389
Query: 424 GEEERFALEILPDMLEKHYGYKLFIPDRDLIPTGTYIEDVARCVDQSKRLIIVMTPNYVV 483
GEE FA+EILP +LEKH+GYKL I +RD++P G ++++ +++S+RLIIV++ +Y+
Sbjct: 390 GEEHTFAVEILPRVLEKHFGYKLCIFERDVVPGGAVVDEIHSLIEKSRRLIIVLSKSYMS 449
Query: 484 RRGWSIFELETRLRNMLVTGEIKVILIECSELRGIMNYQEVEALKHTIKLL---TVIKWH 540
+ELE+ L LV +IK+ILIE + + + L ++KLL V+KW
Sbjct: 450 NE--VRYELESGLHEALVERKIKIILIEFTPV------TDFTFLPQSLKLLKSHRVLKWK 501
Query: 541 GPKCNKLNSKFWKRLQYEMPFKRIEP 566
K NS+FWK L Y MP K ++P
Sbjct: 502 ADKSLSYNSRFWKNLLYLMPAKTVKP 527
>gi|4504659 interleukin 1 receptor, type I precursor [Homo sapiens]
Length = 569
Score = 194 bits (494), Expect = 2e-49
Identities = 153/524 (29%), Positives = 257/524 (49%), Gaps = 48/524 (9%)
Query: 73 SLMWYKSSGPGDFEEPIAFD-GSRMSKEEDSIWFRPTLLQDSGLYACVIRNSTYCMKVSI 131
++ WYK D + P++ + SR+ + ++ +WF P ++DSG Y CV+RNS+YC+++ I
Sbjct: 54 TITWYKD----DSKTPVSTEQASRIHQHKEKLWFVPAKVEDSGHYYCVVRNSSYCLRIKI 109
Query: 132 SLTVGENDTGLCYNSKMKYFEKAELSKSKEISCRDIEDFLLPTRE-PEILWYKECRTKTW 190
S EN+ LCYN++ + +K ++ + C +E F E P++ WYK+C+
Sbjct: 110 SAKFVENEPNLCYNAQAIFKQKLPVAGDGGLVCPYMEFFKNENNELPKLQWYKDCK-PLL 168
Query: 191 RPSIVFK--RDTLLIREVREDDIGNYTCELKY----GGFVVRRTTELTVTAPLTDKPPKL 244
+I F +D L++ V E GNYTC Y + + R E P +
Sbjct: 169 LDNIHFSGVKDRLIVMNVAEKHRGNYTCHASYTYLGKQYPITRVIEFITLEENKPTRPVI 228
Query: 245 LYPMESKLTIQETQLGDSANLTCRAFFGYSGDVSPLIYWMKGEKFIEDLDENRVWESDIR 304
+ P + E LG L C +G +S + YW K + D D+ + E
Sbjct: 229 VSPANETM---EVDLGSQIQLICNV----TGQLSDIAYW-KWNGSVIDEDDPVLGEDYYS 280
Query: 305 ILKEHLGEQEVSISLIVDSVEEGDLGNY----SCYVENGNGRRHASVLLHKRELMYTVEL 360
+ E+ + S + V ++ E + Y +C+ +N +G A + L + +
Sbjct: 281 V--ENPANKRRSTLITVLNISEIESRFYKHPFTCFAKNTHGIDAAYIQLIYPVTNFQKHM 338
Query: 361 AGGLGAILLLLVCLVTIYKCYKIEIMLFYRN--HFGAEELDGDNKDYDAYLSYTKVDPDQ 418
G + +++VC V IYK +KI+I+L+YR+ + D K YDAY+ Y K +
Sbjct: 339 IGICVTLTVIIVCSVFIYKIFKIDIVLWYRDSCYDFLPIKASDGKTYDAYILYPKTVGE- 397
Query: 419 WNQETGEEERFALEILPDMLEKHYGYKLFIPDRDLIPTGTYIEDVARCVDQSKRLIIVM- 477
T + + F ++LP++LEK GYKLFI RD +E + V +S+RLII++
Sbjct: 398 --GSTSDCDIFVFKVLPEVLEKQCGYKLFIYGRDDYVGEDIVEVINENVKKSRRLIIILV 455
Query: 478 --TPNYVVRRGWSIFELETRLRNMLVTGEIKVILIECSELRGIMNYQEV-EALKHTIKLL 534
T + G S E + + N LV IKV+L+ EL I +Y+++ E++K +
Sbjct: 456 RETSGFSWLGGSS--EEQIAMYNALVQDGIKVVLL---ELEKIQDYEKMPESIKFIKQKH 510
Query: 535 TVIKW-----HGPKCNKLNSKFWKRLQYEMPFKRIEPITHEQAL 573
I+W GP+ K ++FWK ++Y MP +R P + Q L
Sbjct: 511 GAIRWSGDFTQGPQSAK--TRFWKNVRYHMPVQRRSPSSKHQLL 552
>gi|4504657 interleukin 18 receptor accessory protein precursor
[Homo sapiens]
Length = 599
Score = 194 bits (493), Expect = 2e-49
Identities = 151/520 (29%), Positives = 251/520 (48%), Gaps = 52/520 (10%)
Query: 74 LMWYKSSGPGDFEEPIAFDGSRMSKEEDSIWFRPTLLQDSGLYACVIR--NSTYCMK--V 129
+ WY+ GD E I + +++ ++ F + +SG Y C + S Y + V
Sbjct: 82 VQWYQQPSNGDPLEDIRKSYPHIIQDKCTLHFLTPGVNNSGSYICRPKMIKSPYDVACCV 141
Query: 130 SISLTVGENDTGLC-YNSKMKYFEKAELSKSKEISCRDIEDFLLPTREPEILWYKECRTK 188
+ L V C Y++ K + L + ISC + + P + WYK +
Sbjct: 142 KMILEVKPQTNASCEYSASHK--QDLLLGSTGSISCPSLS-CQSDAQSPAVTWYKNGKLL 198
Query: 189 TWRPSIVFKRDTLLIREVREDDIGNYTCELKYGGFV----VRRTTELTVTAPLTDKPPKL 244
+ V + + +++ EV + G Y C+ V VR ++ T P +
Sbjct: 199 S-----VERSNRIVVDEVYDYHQGTYVCDYTQSDTVSSWTVRAVVQVRTIVGDTKLKPDI 253
Query: 245 LYPMESKLTIQETQLGDSANLTCRAFFGYSGDVSPLIYWMKGEKFIEDLD-ENRVWESDI 303
L P+E L E +LG ++C+A FG+ +P+I W +I+D D E V +
Sbjct: 254 LDPVEDTL---EVELGKPLTISCKARFGFERVFNPVIKW-----YIKDSDLEWEVSVPEA 305
Query: 304 RILKEHLGEQEVSISLIVDSVEEGDLGN-YSCYVENGNGRRHASVLL-HKRELMYTVELA 361
+ +K L ++ + ++I++ V + DL + C+V+N G SV L KR ++ L
Sbjct: 306 KSIKSTLKDEIIERNIILEKVTQRDLRRKFVCFVQNSIGNTTQSVQLKEKRGVVLLYILL 365
Query: 362 GGLGAILLLLVCLVTIYKCYKIEIMLFYRNHFGAEELDGDNKDYDAYLSYTKVDPDQWNQ 421
G +G ++ +L +Y+ + IEI+L YR + ++ GD KD+DA++SY K W+
Sbjct: 366 GTIGTLVAVLAASALLYRHW-IEIVLLYRTYQSKDQTLGDKKDFDAFVSYAK-----WSS 419
Query: 422 ETGE------EERFALEILPDMLEKHYGYKLFIPDRDLIPTGTYIEDVARCVDQSKRLII 475
E EE AL + PD+LE YGY L + +RD+ P G Y ED+ + +S+R I
Sbjct: 420 FPSEATSSLSEEHLALSLFPDVLENKYGYSLCLLERDVAPGGVYAEDIVSIIKRSRRGIF 479
Query: 476 VMTPNYVVRRGWSIFELETRLRNMLVTGEIKVILIECSELRGIMNYQEVEALKHTIK--- 532
+++PNYV G SIFEL+ + L +K+ILI+ +QE E+L H +K
Sbjct: 480 ILSPNYV--NGPSIFELQAAVNLALDDQTLKLILIK------FCYFQEPESLPHLVKKAL 531
Query: 533 -LLTVIKWHGPKCNKLNSKFWKRLQYEMPFKRIEPITHEQ 571
+L + W G K NS+FW +++Y MP K + T Q
Sbjct: 532 RVLPTVTWRGLKSVPPNSRFWAKMRYHMPVKNSQGFTWNQ 571
>gi|28416902 interleukin 1 receptor-like 2 precursor [Homo sapiens]
Length = 575
Score = 165 bits (417), Expect = 2e-40
Identities = 160/569 (28%), Positives = 261/569 (45%), Gaps = 58/569 (10%)
Query: 27 SADGCTDWSIDIKKYQVLVGEPVRIKCALFYGYIRTNYSLAQSAGLSLMWYKSSGPGDFE 86
+ADGC D I +K + +P C + S +S+ WYK+S
Sbjct: 18 TADGCKD--IFMKNEILSASQPFAFNCT---------FPPITSGEVSVTWYKNSSKIPVS 66
Query: 87 EPIAFDGSRMSKEEDSIWFRPTLLQDSGLYACVIRNSTYCMKVSISLTVGEN---DTGL- 142
+ I SR+ ++E I F P DSG+Y CVI+ C ++ ++LTV E DT +
Sbjct: 67 KIIQ---SRIHQDETWILFLPMEWGDSGVYQCVIKGRDSCHRIHVNLTVFEKHWCDTSIG 123
Query: 143 -CYNSKMKYFEKAELSKSKEISCRDIEDFLLPTREPEILWYKECRT-KTWRPSIVFKRDT 200
N +Y + L K ++C F I WYK+C K R +++ R
Sbjct: 124 GLPNLSDEYKQILHLGKDDSLTCH--LHFPKSCVLGPIKWYKDCNEIKGERFTVLETR-- 179
Query: 201 LLIREVREDDIGNYTCE--LKYGG----FVVRRTTELTVTAPLTDKPPKLLYPMESKLTI 254
LL+ V +D GNY C+ L + G + T +T A PK++YP +
Sbjct: 180 LLVSNVSAEDRGNYACQAILTHSGKQYEVLNGITVSITERAGYGGSVPKIIYPKNHSI-- 237
Query: 255 QETQLGDSANLTCRAFFGYSGDVSPLIYWMKGEKFIEDL--DENRVWESDIRILKEHLGE 312
E QLG + + C + D + L W ++D + R+ E ++ H+
Sbjct: 238 -EVQLGTTLIVDCNVTD--TKDNTNLRCWRVNNTLVDDYYDESKRIREG----VETHVSF 290
Query: 313 QEVSISLIVDSVEEGDLGNYSCYVENGNGRRHASVLLHKRELMYTVELAGGLGAILLLLV 372
+E ++ + + E + +Y G A ++L + L GGL A++ + V
Sbjct: 291 REHNLYTVNITFLEVKMEDYGLPFMCHAGVSTAYIILQLPAPDFRAYLIGGLIALVAVAV 350
Query: 373 CLVTIYKCYKIEIMLFYRNHFGAEELDGDNKDYDAYLSYTKVDPDQWNQETGEEERFALE 432
+V IY +KI+I+L+YR+ F + E D K YDAY+ Y K P + +Q + L
Sbjct: 351 SVVYIYNIFKIDIVLWYRSAFHSTETIVDGKLYDAYVLYPK--PHKESQRHA-VDALVLN 407
Query: 433 ILPDMLEKHYGYKLFIPDRDLIPTGTYIEDVARCVDQSKRLIIVMTPNYVVRRGWSIF-- 490
ILP++LE+ GYKLFI RD P + V +RLI+++ P + G+ +
Sbjct: 408 ILPEVLERQCGYKLFIFGRDEFPGQAVANVIDENVKLCRRLIVIVVPESL---GFGLLKN 464
Query: 491 --ELETRLRNMLVTGEIKVILIECSELRGIMNYQEV-EALKHTIKLLTVIKWHG---PKC 544
E + + + L+ +KVILI EL I +Y + E++++ + I+WHG +
Sbjct: 465 LSEEQIAVYSALIQDGMKVILI---ELEKIEDYTVMPESIQYIKQKHGAIRWHGDFTEQS 521
Query: 545 NKLNSKFWKRLQYEMPFKRIEPITHEQAL 573
+ +KFWK ++Y MP +R P Q L
Sbjct: 522 QCMKTKFWKTVRYHMPPRRCRPFPPVQLL 550
>gi|27894324 interleukin 1 receptor-like 1 isoform 1 precursor [Homo
sapiens]
Length = 556
Score = 162 bits (409), Expect = 1e-39
Identities = 131/472 (27%), Positives = 220/472 (46%), Gaps = 25/472 (5%)
Query: 105 FRPTLLQDSGLYACVIRNSTYCMKVSISLTVGENDTGLCYNSKMKYFEKAELSKSKEISC 164
F P + DSG+Y C++R+ T+ ++T+ + + + Y + K+ +I C
Sbjct: 74 FLPAAVADSGIYTCIVRSPTFNRTGYANVTIYKKQSDCNVPDYLMYSTVSGSEKNSKIYC 133
Query: 165 RDIEDFLLPTREPEILWYKECRTKTWRPSIVFKRDTLLIREVREDDIGNYTCELKYGGFV 224
I+ L + W+K C+ K L+I V +D G+YTC+ +
Sbjct: 134 PTID---LYNWTAPLEWFKNCQALQGSRYRAHK-SFLVIDNVMTEDAGDYTCKFIHNENG 189
Query: 225 VRRTTELTVTAPLTDKPPKLLYPM---ESKLTIQETQLGDSANLTCRAFFGYSGDVSPLI 281
+ T + + D+ L+P+ ++ I+E ++G +ANLTC A FG +
Sbjct: 190 ANYSVTATRSFTVKDEQGFSLFPVIGAPAQNEIKEVEIGKNANLTCSACFGKGTQFLAAV 249
Query: 282 YWMKGEKFIEDLDENRVWESDIRILKEHLGEQEVSISLIVDSVEEGDLG-NYSCYVENGN 340
W I D E R+ + + + G + + L + V+E DL Y C N +
Sbjct: 250 LWQLNGTKITDFGEPRIQQEEGQNQSFSNGLACLDMVLRIADVKEEDLLLQYDCLALNLH 309
Query: 341 GRRHASVLLHKRELM--YTVELAGGLGAILLLLV-CLVTIYKCYKIEIMLFYRNHFGAEE 397
G R +V L ++ + +++ + ++ L+L+ LV I K + IE L +R+ +
Sbjct: 310 GLRRHTVRLSRKNPIDHHSIYCIIAVCSVFLMLINVLVIILKMFWIEATLLWRDIAKPYK 369
Query: 398 LDGDNKDYDAYLSYTKVDPDQWNQET---GEEERFALEILPDMLEKHYGYKLFIPDRDLI 454
D K YDAY+ Y P + T E F +ILPD+LE GY L I RD++
Sbjct: 370 TRNDGKLYDAYVVY----PRNYKSSTDGASRVEHFVHQILPDVLENKCGYTLCIYGRDML 425
Query: 455 PTGTYIEDVARCVDQSKRLIIVMTPNYVVRRGWSIFELETRLRNMLVTGEIKVILIE--- 511
P + V + +S+R I ++TP + ++ +E E L L+ + KVILIE
Sbjct: 426 PGEDVVTAVETNIRKSRRHIFILTPQITHNKEFA-YEQEVALHCALIQNDAKVILIEMEA 484
Query: 512 CSELRGIMNYQEVEALKHTIKLLTVIKW---HGPKCNKLNSKFWKRLQYEMP 560
SEL + ++L+H +K+ IKW H LNSKFWK ++Y+MP
Sbjct: 485 LSELDMLQAEALQDSLQHLMKVQGTIKWREDHIANKRSLNSKFWKHVRYQMP 536
>gi|19882209 interleukin 1 receptor accessory protein isoform 2
[Homo sapiens]
Length = 356
Score = 154 bits (389), Expect = 3e-37
Identities = 97/300 (32%), Positives = 154/300 (51%), Gaps = 22/300 (7%)
Query: 8 LILLYATFTQSLKVVTKRGSADGCTDWSID-IKKYQVLVGEPVRIKCALFYGYIRTNYSL 66
+ LL+ + + + +++ C DW +D +++ QV EP RIKC LF +++ NYS
Sbjct: 1 MTLLWCVVSLYFYGILQSDASERCDDWGLDTMRQIQVFEDEPARIKCPLFEHFLKFNYST 60
Query: 67 AQSAGLSLMWYKSSGPGDFEEPIAF--DGSRMSKEEDSIWFRPTLLQDSGLYACVIRNST 124
A SAGL+L+WY + D EEPI F +R+SKE+D +WFRPTLL D+G Y C++RN+T
Sbjct: 61 AHSAGLTLIWYWTRQDRDLEEPINFRLPENRISKEKDVLWFRPTLLNDTGNYTCMLRNTT 120
Query: 125 YCMKVSISLTVGENDTGLCYNSKMK------YFEKAELSKSKEISCRDIEDFLLPTREPE 178
YC KV+ L V + D+ C+NS MK Y E + I+C +++ + + +P
Sbjct: 121 YCSKVAFPLEVVQKDS--CFNSPMKLPVHKLYIEYG----IQRITCPNVDGYFPSSVKPT 174
Query: 179 ILWYKECRTKTWRPSIVFKRDTLLIREVREDDIGNYTCELKY--GGFVVRRTTELTVT-- 234
I WY C +++ + L + GNYTC + Y G T LTV
Sbjct: 175 ITWYMGCYKIQNFNNVIPEGMNLSFLIALISNNGNYTCVVTYPENGRTFHLTRTLTVKVV 234
Query: 235 -APLTDKPPKLLYPMESKLTIQETQLGDSANLTCRAFFGYSGDVSPLIYWMKGEKFIEDL 293
+P PP + P + + E + G+ + C +F + D ++W K +D+
Sbjct: 235 GSPKNAVPPVIHSPNDH--VVYEKEPGEELLIPCTVYFSFLMDSRNEVWWTIDGKKPDDI 292
>gi|27894334 interleukin 1 receptor, type II precursor [Homo
sapiens]
Length = 398
Score = 107 bits (266), Expect = 5e-23
Identities = 88/351 (25%), Positives = 153/351 (43%), Gaps = 47/351 (13%)
Query: 9 ILLYATFTQSLKVVTKRGSADGCTDWSIDIKKYQVLVGEPVRIKCALFYGYIRTNYSLAQ 68
+L+ +L+ G+A C K+ L GEPV ++C ++ + S
Sbjct: 6 VLVMGVSAFTLQPAAHTGAARSCRFRGRHYKREFRLEGEPVALRCPQVPYWLWASVS--- 62
Query: 69 SAGLSLMWYKSSG----PGDFEEPIAFDGSRMSKEEDSIWFRPTLLQDSGLYACVIRNST 124
++L W+K+ PG+ E +RM ++ ++W P L +DSG Y C RN++
Sbjct: 63 -PRINLTWHKNDSARTVPGEEE-------TRMWAQDGALWLLPALQEDSGTYVCTTRNAS 114
Query: 125 YCMKVSISLTVGENDTGLCYNSKMKYFEKAELSKSKEISCRDIEDFLLPTREPEILWYKE 184
YC K+SI L V EN + + Y + LS S + C D+ +F + +I WYK+
Sbjct: 115 YCDKMSIELRVFENTD--AFLPFISYPQILTLSTSGVLVCPDLSEFTRDKTDVKIQWYKD 172
Query: 185 CRTKTWRPSIVFKRDT-----------LLIREVREDDIGNYTCELKYG----GFVVRRTT 229
S++ +D LL+ +V +D G Y C L + + + R+
Sbjct: 173 --------SLLLDKDNEKFLSVRGTTHLLVHDVALEDAGYYRCVLTFAHEGQQYNITRSI 224
Query: 230 ELTVTAPLTDKPPKLLYPMESKLTIQETQLGDSANLTCRAFFGYSGDVSPLIYWMKGEKF 289
EL + + P ++ P+++ LG + C+ F G ++ +++W +
Sbjct: 225 ELRIKKKKEETIPVIISPLKT----ISASLGSRLTIPCKVFLGTGTPLTTMLWWTANDTH 280
Query: 290 IED-LDENRVWESDIRILKEHLGEQEVSISLIVDSVEEGDLG-NYSCYVEN 338
IE RV E + E+ E + + LI D V DL ++ C V N
Sbjct: 281 IESAYPGGRVTEGPRQEYSEN-NENYIEVPLIFDPVTREDLHMDFKCVVHN 330
>gi|4758598 interleukin 1 receptor, type II precursor [Homo sapiens]
Length = 398
Score = 107 bits (266), Expect = 5e-23
Identities = 88/351 (25%), Positives = 153/351 (43%), Gaps = 47/351 (13%)
Query: 9 ILLYATFTQSLKVVTKRGSADGCTDWSIDIKKYQVLVGEPVRIKCALFYGYIRTNYSLAQ 68
+L+ +L+ G+A C K+ L GEPV ++C ++ + S
Sbjct: 6 VLVMGVSAFTLQPAAHTGAARSCRFRGRHYKREFRLEGEPVALRCPQVPYWLWASVS--- 62
Query: 69 SAGLSLMWYKSSG----PGDFEEPIAFDGSRMSKEEDSIWFRPTLLQDSGLYACVIRNST 124
++L W+K+ PG+ E +RM ++ ++W P L +DSG Y C RN++
Sbjct: 63 -PRINLTWHKNDSARTVPGEEE-------TRMWAQDGALWLLPALQEDSGTYVCTTRNAS 114
Query: 125 YCMKVSISLTVGENDTGLCYNSKMKYFEKAELSKSKEISCRDIEDFLLPTREPEILWYKE 184
YC K+SI L V EN + + Y + LS S + C D+ +F + +I WYK+
Sbjct: 115 YCDKMSIELRVFENTD--AFLPFISYPQILTLSTSGVLVCPDLSEFTRDKTDVKIQWYKD 172
Query: 185 CRTKTWRPSIVFKRDT-----------LLIREVREDDIGNYTCELKYG----GFVVRRTT 229
S++ +D LL+ +V +D G Y C L + + + R+
Sbjct: 173 --------SLLLDKDNEKFLSVRGTTHLLVHDVALEDAGYYRCVLTFAHEGQQYNITRSI 224
Query: 230 ELTVTAPLTDKPPKLLYPMESKLTIQETQLGDSANLTCRAFFGYSGDVSPLIYWMKGEKF 289
EL + + P ++ P+++ LG + C+ F G ++ +++W +
Sbjct: 225 ELRIKKKKEETIPVIISPLKT----ISASLGSRLTIPCKVFLGTGTPLTTMLWWTANDTH 280
Query: 290 IED-LDENRVWESDIRILKEHLGEQEVSISLIVDSVEEGDLG-NYSCYVEN 338
IE RV E + E+ E + + LI D V DL ++ C V N
Sbjct: 281 IESAYPGGRVTEGPRQEYSEN-NENYIEVPLIFDPVTREDLHMDFKCVVHN 330
>gi|205277451 single Ig IL-1R-related molecule [Homo sapiens]
Length = 410
Score = 89.4 bits (220), Expect = 1e-17
Identities = 88/327 (26%), Positives = 150/327 (45%), Gaps = 25/327 (7%)
Query: 239 DKPPKLLYPMESKLTIQETQLGDSANLTCRAFFGYSGDVS-PLIYWMKGEKFIEDLDENR 297
D+ P L P E + + LG S L C A+ S P + W+K +
Sbjct: 6 DRAPDFLSPSEDQ--VLRPALGSSVALNCTAWVVSGPHCSLPSVQWLKDGLPLGIGGHYS 63
Query: 298 VWESDIRILKEHLGEQEVSISLIVDSVEEGDLGNYSCYVENGNGRRHASVLLHKRELMYT 357
+ E +K +L E VS L V+ G ++C ++N + +S L + T
Sbjct: 64 LHEYSW--VKANLSEVLVSSVLGVNVTSTEVYGAFTCSIQNIS---FSSFTLQRAGP--T 116
Query: 358 VELAGGLGAILLLLVCLVT--IYKCYKIEIMLFYRNHFGAEELDGDNKDYDAYLSYTKVD 415
+A L ++L+LL L+ +Y ++ ++L+Y++ +G E++ D K YDAY+SY+
Sbjct: 117 SHVAAVLASLLVLLALLLAALLYVKCRLNVLLWYQDAYGEVEIN-DGKLYDAYVSYS--- 172
Query: 416 PDQWNQETGEEERFALEILPDMLEKHYGYKLFIPDRDLIPTGTYIEDVARCVDQSKRLII 475
+ E+ +F IL LE+ GYKLF+ DRDL+P D+ + + +RLI+
Sbjct: 173 ------DCPEDRKFVNFILKPQLERRRGYKLFLDDRDLLPRAEPSADLLVNLSRCRRLIV 226
Query: 476 VMTPNYVVRRGWSIFELETRLRNMLVTGEIKVILIECSELRGIMNYQEVEALKHTIKLLT 535
V++ + + R W L +L + I I R + + L+ L+T
Sbjct: 227 VLSDAF-LSRAWCSHSFREGLCRLLELTR-RPIFITFEGQRRDPAHPALRLLRQHRHLVT 284
Query: 536 VIKWHGPKCNKLNSKFWKRLQYEMPFK 562
++ W P +S FWK +Q +P K
Sbjct: 285 LLLWR-PGSVTPSSDFWKEVQLALPRK 310
>gi|205277449 single Ig IL-1R-related molecule [Homo sapiens]
Length = 410
Score = 89.4 bits (220), Expect = 1e-17
Identities = 88/327 (26%), Positives = 150/327 (45%), Gaps = 25/327 (7%)
Query: 239 DKPPKLLYPMESKLTIQETQLGDSANLTCRAFFGYSGDVS-PLIYWMKGEKFIEDLDENR 297
D+ P L P E + + LG S L C A+ S P + W+K +
Sbjct: 6 DRAPDFLSPSEDQ--VLRPALGSSVALNCTAWVVSGPHCSLPSVQWLKDGLPLGIGGHYS 63
Query: 298 VWESDIRILKEHLGEQEVSISLIVDSVEEGDLGNYSCYVENGNGRRHASVLLHKRELMYT 357
+ E +K +L E VS L V+ G ++C ++N + +S L + T
Sbjct: 64 LHEYSW--VKANLSEVLVSSVLGVNVTSTEVYGAFTCSIQNIS---FSSFTLQRAGP--T 116
Query: 358 VELAGGLGAILLLLVCLVT--IYKCYKIEIMLFYRNHFGAEELDGDNKDYDAYLSYTKVD 415
+A L ++L+LL L+ +Y ++ ++L+Y++ +G E++ D K YDAY+SY+
Sbjct: 117 SHVAAVLASLLVLLALLLAALLYVKCRLNVLLWYQDAYGEVEIN-DGKLYDAYVSYS--- 172
Query: 416 PDQWNQETGEEERFALEILPDMLEKHYGYKLFIPDRDLIPTGTYIEDVARCVDQSKRLII 475
+ E+ +F IL LE+ GYKLF+ DRDL+P D+ + + +RLI+
Sbjct: 173 ------DCPEDRKFVNFILKPQLERRRGYKLFLDDRDLLPRAEPSADLLVNLSRCRRLIV 226
Query: 476 VMTPNYVVRRGWSIFELETRLRNMLVTGEIKVILIECSELRGIMNYQEVEALKHTIKLLT 535
V++ + + R W L +L + I I R + + L+ L+T
Sbjct: 227 VLSDAF-LSRAWCSHSFREGLCRLLELTR-RPIFITFEGQRRDPAHPALRLLRQHRHLVT 284
Query: 536 VIKWHGPKCNKLNSKFWKRLQYEMPFK 562
++ W P +S FWK +Q +P K
Sbjct: 285 LLLWR-PGSVTPSSDFWKEVQLALPRK 310
>gi|205277445 single Ig IL-1R-related molecule [Homo sapiens]
Length = 410
Score = 89.4 bits (220), Expect = 1e-17
Identities = 88/327 (26%), Positives = 150/327 (45%), Gaps = 25/327 (7%)
Query: 239 DKPPKLLYPMESKLTIQETQLGDSANLTCRAFFGYSGDVS-PLIYWMKGEKFIEDLDENR 297
D+ P L P E + + LG S L C A+ S P + W+K +
Sbjct: 6 DRAPDFLSPSEDQ--VLRPALGSSVALNCTAWVVSGPHCSLPSVQWLKDGLPLGIGGHYS 63
Query: 298 VWESDIRILKEHLGEQEVSISLIVDSVEEGDLGNYSCYVENGNGRRHASVLLHKRELMYT 357
+ E +K +L E VS L V+ G ++C ++N + +S L + T
Sbjct: 64 LHEYSW--VKANLSEVLVSSVLGVNVTSTEVYGAFTCSIQNIS---FSSFTLQRAGP--T 116
Query: 358 VELAGGLGAILLLLVCLVT--IYKCYKIEIMLFYRNHFGAEELDGDNKDYDAYLSYTKVD 415
+A L ++L+LL L+ +Y ++ ++L+Y++ +G E++ D K YDAY+SY+
Sbjct: 117 SHVAAVLASLLVLLALLLAALLYVKCRLNVLLWYQDAYGEVEIN-DGKLYDAYVSYS--- 172
Query: 416 PDQWNQETGEEERFALEILPDMLEKHYGYKLFIPDRDLIPTGTYIEDVARCVDQSKRLII 475
+ E+ +F IL LE+ GYKLF+ DRDL+P D+ + + +RLI+
Sbjct: 173 ------DCPEDRKFVNFILKPQLERRRGYKLFLDDRDLLPRAEPSADLLVNLSRCRRLIV 226
Query: 476 VMTPNYVVRRGWSIFELETRLRNMLVTGEIKVILIECSELRGIMNYQEVEALKHTIKLLT 535
V++ + + R W L +L + I I R + + L+ L+T
Sbjct: 227 VLSDAF-LSRAWCSHSFREGLCRLLELTR-RPIFITFEGQRRDPAHPALRLLRQHRHLVT 284
Query: 536 VIKWHGPKCNKLNSKFWKRLQYEMPFK 562
++ W P +S FWK +Q +P K
Sbjct: 285 LLLWR-PGSVTPSSDFWKEVQLALPRK 310
>gi|27894328 interleukin 1 receptor-like 1 isoform 2 precursor [Homo
sapiens]
Length = 328
Score = 75.9 bits (185), Expect = 1e-13
Identities = 61/252 (24%), Positives = 110/252 (43%), Gaps = 8/252 (3%)
Query: 105 FRPTLLQDSGLYACVIRNSTYCMKVSISLTVGENDTGLCYNSKMKYFEKAELSKSKEISC 164
F P + DSG+Y C++R+ T+ ++T+ + + + Y + K+ +I C
Sbjct: 74 FLPAAVADSGIYTCIVRSPTFNRTGYANVTIYKKQSDCNVPDYLMYSTVSGSEKNSKIYC 133
Query: 165 RDIEDFLLPTREPEILWYKECRTKTWRPSIVFKRDTLLIREVREDDIGNYTCELKYGGFV 224
I+ L + W+K C+ K L+I V +D G+YTC+ +
Sbjct: 134 PTID---LYNWTAPLEWFKNCQALQGSRYRAHK-SFLVIDNVMTEDAGDYTCKFIHNENG 189
Query: 225 VRRTTELTVTAPLTDKPPKLLYPM---ESKLTIQETQLGDSANLTCRAFFGYSGDVSPLI 281
+ T + + D+ L+P+ ++ I+E ++G +ANLTC A FG +
Sbjct: 190 ANYSVTATRSFTVKDEQGFSLFPVIGAPAQNEIKEVEIGKNANLTCSACFGKGTQFLAAV 249
Query: 282 YWMKGEKFIEDLDENRVWESDIRILKEHLGEQEVSISLIVDSVEEGD-LGNYSCYVENGN 340
W I D E R+ + + + G + + L + V+E D L Y C N +
Sbjct: 250 LWQLNGTKITDFGEPRIQQEEGQNQSFSNGLACLDMVLRIADVKEEDLLLQYDCLALNLH 309
Query: 341 GRRHASVLLHKR 352
G R +V L ++
Sbjct: 310 GLRRHTVRLSRK 321
>gi|54607118 leucine-rich repeats and immunoglobulin-like domains 1
[Homo sapiens]
Length = 1093
Score = 57.8 bits (138), Expect = 3e-08
Identities = 73/320 (22%), Positives = 127/320 (39%), Gaps = 64/320 (20%)
Query: 44 LVGEPVRIKCALFYGYIRTNYSLAQSAGLSLMWYK------SSGPGDFEEPIAFDGSRMS 97
+VG+ +R C+ + + S+ ++ W K ++ +F A DG M
Sbjct: 507 MVGKDIRFTCSA---------ASSSSSPMTFAWKKDNEVLTNADMENFVHVHAQDGEVM- 556
Query: 98 KEEDSIWFRPTLLQDSGLYACVIRN---STYCMKVSISLTVGENDTGLCYNSKMKYFEKA 154
+ + R G Y CVI N STY K +++ V + T ++ ++ A
Sbjct: 557 EYTTILHLRQVTFGHEGRYQCVITNHFGSTYSHKARLTVNVLPSFTKTPHDITIRTTTMA 616
Query: 155 ELSKSKEISCRDIEDFLLPTREPEILWYKECRT-----KTWRPSIVFKRDTLLIREVRED 209
L E P+I W K+ T + R ++ D I +V+ D
Sbjct: 617 RL-----------ECAATGHPNPQIAWQKDGGTDFPAARERRMHVMPDDDVFFITDVKID 665
Query: 210 DIGNYTCELKYGGFVVRRTTELTVTAPLTDKPPKLLYPMESKLTIQETQLGDSANLTCRA 269
D G Y+C + + LTV + P L+ P+E ++ +G++ L C+A
Sbjct: 666 DAGVYSCTAQNSAGSISANATLTVL-----ETPSLVVPLEDRVV----SVGETVALQCKA 716
Query: 270 FFGYSGDVSPLIYWMKGEKFIEDLDENRVWESDIRILKEHLGEQEVSISLIVDSVEEGDL 329
+G+ P I W KG++ + L E D ++L +V +V D
Sbjct: 717 ----TGNPPPRITWFKGDRPLS-LTERHHLTPDNQLL-------------VVQNVVAEDA 758
Query: 330 GNYSCYVEN--GNGRRHASV 347
G Y+C + N G R H+ +
Sbjct: 759 GRYTCEMSNTLGTERAHSQL 778
Score = 41.2 bits (95), Expect = 0.003
Identities = 40/163 (24%), Positives = 72/163 (44%), Gaps = 15/163 (9%)
Query: 74 LMWYKSSGPGDFEEPIAFDGSRMSKEEDSIWFRPTL-LQDSGLYACVIRNSTYCMKVSIS 132
+ W K G DF P A + +D ++F + + D+G+Y+C +NS + + +
Sbjct: 630 IAWQKDGGT-DF--PAARERRMHVMPDDDVFFITDVKIDDAGVYSCTAQNSAGSISANAT 686
Query: 133 LTVGENDTGLCYNSKMKYFEKAELSKSKEISCRDIEDFLLPTREPEILWYKECR--TKTW 190
LTV E S + E +S + ++ ++ P I W+K R + T
Sbjct: 687 LTVLETP------SLVVPLEDRVVSVGETVA---LQCKATGNPPPRITWFKGDRPLSLTE 737
Query: 191 RPSIVFKRDTLLIREVREDDIGNYTCELKYGGFVVRRTTELTV 233
R + L+++ V +D G YTCE+ R ++L+V
Sbjct: 738 RHHLTPDNQLLVVQNVVAEDAGRYTCEMSNTLGTERAHSQLSV 780
>gi|41350337 toll-like receptor 1 [Homo sapiens]
Length = 786
Score = 57.4 bits (137), Expect = 4e-08
Identities = 63/269 (23%), Positives = 116/269 (43%), Gaps = 31/269 (11%)
Query: 310 LGEQEVSISLIVDSVEEGDLGNYSC-YVENGNGRRHASVLLHKRELMYTVELAGGLGAIL 368
LGE +I + V EG +Y C Y E+ G + + T+ + + +L
Sbjct: 532 LGEFVKNIDQVSSEVLEGWPDSYKCDYPESYRGTLLKDFHMSELSCNITLLIVTIVATML 591
Query: 369 LLLVCLVTIYKCYKIEIMLFYR------------NHFGAEELDGDNKDYDAYLSYTKVDP 416
+L V + ++ C +++ + R + EEL N + A++SY+ D
Sbjct: 592 VLAVTVTSL--CSYLDLPWYLRMVCQWTQTRRRARNIPLEELQR-NLQFHAFISYSGHD- 647
Query: 417 DQWNQETGEEERFALEILPDMLEKHYGYKLFIPDRDLIPTGTYIEDVARCVDQSKRLIIV 476
W + E+LP+ LEK G ++ + +R+ +P + +E++ C+++S + I V
Sbjct: 648 SFWVKN---------ELLPN-LEKE-GMQICLHERNFVPGKSIVENIITCIEKSYKSIFV 696
Query: 477 MTPNYVVRRGWSIFELETRLRNMLVTGEIKVILIECSELRGIMNYQEVEALKHTIKLLTV 536
++PN+ V+ W +EL N+ G +ILI + LK + T
Sbjct: 697 LSPNF-VQSEWCHYELYFAHHNLFHEGSNSLILILLEPIPQYSIPSSYHKLKSLMARRTY 755
Query: 537 IKWHGPKCNKLNSKFWKRLQYEMPFKRIE 565
++W PK FW L+ + K E
Sbjct: 756 LEW--PKEKSKRGLFWANLRAAINIKLTE 782
>gi|20143971 toll-like receptor 6 [Homo sapiens]
Length = 796
Score = 52.0 bits (123), Expect = 2e-06
Identities = 61/255 (23%), Positives = 110/255 (43%), Gaps = 33/255 (12%)
Query: 316 SISLIVDSVEEGDLGNYSC-YVENGNGRRHASVLLHKRELMYTVELA-GGLGAILLLLVC 373
+I + V EG +Y C Y E+ G H EL + L +GA +L+L
Sbjct: 543 NIDQVSSEVLEGWPDSYKCDYPESYRGSPLKD--FHMSELSCNITLLIVTIGATMLVLAV 600
Query: 374 LVTIYKCYKIEIMLFYR------------NHFGAEELDGDNKDYDAYLSYTKVDPDQWNQ 421
VT C +++ + R + EEL N + A++SY++ D W +
Sbjct: 601 TVTSL-CIYLDLPWYLRMVCQWTQTRRRARNIPLEELQR-NLQFHAFISYSEHD-SAWVK 657
Query: 422 ETGEEERFALEILPDMLEKHYGYKLFIPDRDLIPTGTYIEDVARCVDQSKRLIIVMTPNY 481
E++P LEK ++ + +R+ +P + +E++ C+++S + I V++PN+
Sbjct: 658 S---------ELVP-YLEKE-DIQICLHERNFVPGKSIVENIINCIEKSYKSIFVLSPNF 706
Query: 482 VVRRGWSIFELETRLRNMLVTGEIKVILIECSELRGIMNYQEVEALKHTIKLLTVIKWHG 541
V+ W +EL N+ G +ILI + + LK + T ++W
Sbjct: 707 -VQSEWCHYELYFAHHNLFHEGSNNLILILLEPIPQNSIPNKYHKLKALMTQRTYLQW-- 763
Query: 542 PKCNKLNSKFWKRLQ 556
PK FW ++
Sbjct: 764 PKEKSKRGLFWANIR 778
>gi|116008194 myosin light chain kinase isoform 3A [Homo sapiens]
Length = 1863
Score = 50.4 bits (119), Expect = 5e-06
Identities = 68/303 (22%), Positives = 112/303 (36%), Gaps = 46/303 (15%)
Query: 87 EPIAFDGSRMSKEEDSIWFRPTLLQDSGLYACVIRNSTYCMKVSISLTVGENDTGLCYNS 146
+PI + S + + L +D G Y C+ N+ + S +TV E + +
Sbjct: 552 QPIQYARSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKS----SR 607
Query: 147 KMKYFEKAELSKS---------KEISCRDIEDFLLPTR-----EPEILWYKECRTKTWRP 192
K +Y SK ++ D + + PE++W
Sbjct: 608 KSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESE 667
Query: 193 SIVFKR----DTLLIREVREDDIGNYTCELKYGGFVVRRTTELTVTAPLTDKPPKLLYPM 248
F++ +L I+EV +D G YTCE VR LTV P P +
Sbjct: 668 DFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFI--- 724
Query: 249 ESKLTIQETQLGDSANLTCRAFFGYSGDVSPLIYWMK-GEKFIEDLDENRVWESD---IR 304
SK LG S ++C +GD P ++W++ G+ +D V +++
Sbjct: 725 -SKPRSVTASLGQSVLISC----AIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTL 779
Query: 305 ILKE----HLGEQEVSISLIVDSVEEGDLGNYSCYVENGNGRRHASVLLHKRELMYTVEL 360
+LK+ H G+ E+ + + +G SC V A L RE +L
Sbjct: 780 VLKKVQPWHAGQYEILL--------KNRVGECSCQVSLMLQNSSARALPRGREPASCEDL 831
Query: 361 AGG 363
GG
Sbjct: 832 CGG 834
Score = 47.0 bits (110), Expect = 6e-05
Identities = 51/209 (24%), Positives = 84/209 (40%), Gaps = 56/209 (26%)
Query: 176 EPEILWYKECRTKTWRPSIVFK---RDT--LLIREVREDDIGNYTCELKYGGFVVRRTTE 230
EP++ W++ + T + R T L+I V E+D G YTCE G + T E
Sbjct: 61 EPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVE 120
Query: 231 LTVTA--------PLTDK---------------------PPKLLYPMESKLTIQETQLGD 261
LTV P+ K PPK + ++ ++E Q+G
Sbjct: 121 LTVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKFATKL-GRVVVKEGQMG- 178
Query: 262 SANLTCRAFFGYSGDVSPLIYWMKGEKFIEDLDENRVWESD-IRILKEHLGEQEVSISLI 320
+C+ +G P + W+KG ++ V E + +++L+ H
Sbjct: 179 --RFSCK----ITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIH----------- 221
Query: 321 VDSVEEGDLGNYSCYVENGNGRRHASVLL 349
V + D+G Y+C V NG+G+ S L
Sbjct: 222 --GVNQDDVGVYTCLVVNGSGKASMSAEL 248
Score = 37.0 bits (84), Expect = 0.062
Identities = 61/265 (23%), Positives = 99/265 (37%), Gaps = 52/265 (19%)
Query: 111 QDSGLYACVIRNSTYCMKVSISLTVGENDTGLCYNSKMKYFEKAELSKSKEISCRDIE-- 168
+DSG Y+C N+ + S +L V ++ E A S C IE
Sbjct: 480 RDSGTYSCTASNAQGQLSCSWTLQV----------ERLAVMEVAPSFSSVLKDCAVIEGQ 529
Query: 169 DFLLP-----TREPEILWYKECRTKTWRPSIVFKRDT-------LLIREVREDDIGNYTC 216
DF+L T P I W + I + R T L I++ +D G YTC
Sbjct: 530 DFVLQCSVRGTPVPRITWLLNGQ------PIQYARSTCEAGVAELHIQDALPEDHGTYTC 583
Query: 217 ELKYGGFVVRRTTELTVTAPLTDKPPKLLYPM-ESKLT-------IQETQLGDSANLTCR 268
+ V + +TV + + + L P+ SK T + + ++ D + +T
Sbjct: 584 LAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMT 643
Query: 269 AFFGYSGDVSPLIYWMKGEKFIEDLDENRVWESDIRILKEHLGEQEVSISLIVDSVEEGD 328
SG+ P + W+ + N + ES+ H ++ SL + V D
Sbjct: 644 V--QVSGNPPPEVIWLH--------NGNEIQESE----DFHFEQRGTQHSLCIQEVFPED 689
Query: 329 LGNYSCYVENGNGRRHASVLLHKRE 353
G Y+C N G +L +E
Sbjct: 690 TGTYTCEAWNSAGEVRTQAVLTVQE 714
>gi|116008192 myosin light chain kinase isoform 1 [Homo sapiens]
Length = 1914
Score = 50.4 bits (119), Expect = 5e-06
Identities = 68/303 (22%), Positives = 112/303 (36%), Gaps = 46/303 (15%)
Query: 87 EPIAFDGSRMSKEEDSIWFRPTLLQDSGLYACVIRNSTYCMKVSISLTVGENDTGLCYNS 146
+PI + S + + L +D G Y C+ N+ + S +TV E + +
Sbjct: 552 QPIQYARSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKS----SR 607
Query: 147 KMKYFEKAELSKS---------KEISCRDIEDFLLPTR-----EPEILWYKECRTKTWRP 192
K +Y SK ++ D + + PE++W
Sbjct: 608 KSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESE 667
Query: 193 SIVFKR----DTLLIREVREDDIGNYTCELKYGGFVVRRTTELTVTAPLTDKPPKLLYPM 248
F++ +L I+EV +D G YTCE VR LTV P P +
Sbjct: 668 DFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFI--- 724
Query: 249 ESKLTIQETQLGDSANLTCRAFFGYSGDVSPLIYWMK-GEKFIEDLDENRVWESD---IR 304
SK LG S ++C +GD P ++W++ G+ +D V +++
Sbjct: 725 -SKPRSVTASLGQSVLISC----AIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTL 779
Query: 305 ILKE----HLGEQEVSISLIVDSVEEGDLGNYSCYVENGNGRRHASVLLHKRELMYTVEL 360
+LK+ H G+ E+ + + +G SC V A L RE +L
Sbjct: 780 VLKKVQPWHAGQYEILL--------KNRVGECSCQVSLMLQNSSARALPRGREPASCEDL 831
Query: 361 AGG 363
GG
Sbjct: 832 CGG 834
Score = 47.0 bits (110), Expect = 6e-05
Identities = 51/209 (24%), Positives = 84/209 (40%), Gaps = 56/209 (26%)
Query: 176 EPEILWYKECRTKTWRPSIVFK---RDT--LLIREVREDDIGNYTCELKYGGFVVRRTTE 230
EP++ W++ + T + R T L+I V E+D G YTCE G + T E
Sbjct: 61 EPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVE 120
Query: 231 LTVTA--------PLTDK---------------------PPKLLYPMESKLTIQETQLGD 261
LTV P+ K PPK + ++ ++E Q+G
Sbjct: 121 LTVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKFATKL-GRVVVKEGQMG- 178
Query: 262 SANLTCRAFFGYSGDVSPLIYWMKGEKFIEDLDENRVWESD-IRILKEHLGEQEVSISLI 320
+C+ +G P + W+KG ++ V E + +++L+ H
Sbjct: 179 --RFSCK----ITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIH----------- 221
Query: 321 VDSVEEGDLGNYSCYVENGNGRRHASVLL 349
V + D+G Y+C V NG+G+ S L
Sbjct: 222 --GVNQDDVGVYTCLVVNGSGKASMSAEL 248
Score = 37.0 bits (84), Expect = 0.062
Identities = 61/265 (23%), Positives = 99/265 (37%), Gaps = 52/265 (19%)
Query: 111 QDSGLYACVIRNSTYCMKVSISLTVGENDTGLCYNSKMKYFEKAELSKSKEISCRDIE-- 168
+DSG Y+C N+ + S +L V ++ E A S C IE
Sbjct: 480 RDSGTYSCTASNAQGQLSCSWTLQV----------ERLAVMEVAPSFSSVLKDCAVIEGQ 529
Query: 169 DFLLP-----TREPEILWYKECRTKTWRPSIVFKRDT-------LLIREVREDDIGNYTC 216
DF+L T P I W + I + R T L I++ +D G YTC
Sbjct: 530 DFVLQCSVRGTPVPRITWLLNGQ------PIQYARSTCEAGVAELHIQDALPEDHGTYTC 583
Query: 217 ELKYGGFVVRRTTELTVTAPLTDKPPKLLYPM-ESKLT-------IQETQLGDSANLTCR 268
+ V + +TV + + + L P+ SK T + + ++ D + +T
Sbjct: 584 LAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMT 643
Query: 269 AFFGYSGDVSPLIYWMKGEKFIEDLDENRVWESDIRILKEHLGEQEVSISLIVDSVEEGD 328
SG+ P + W+ + N + ES+ H ++ SL + V D
Sbjct: 644 V--QVSGNPPPEVIWLH--------NGNEIQESE----DFHFEQRGTQHSLCIQEVFPED 689
Query: 329 LGNYSCYVENGNGRRHASVLLHKRE 353
G Y+C N G +L +E
Sbjct: 690 TGTYTCEAWNSAGEVRTQAVLTVQE 714
>gi|116008190 myosin light chain kinase isoform 3B [Homo sapiens]
Length = 1794
Score = 50.4 bits (119), Expect = 5e-06
Identities = 68/303 (22%), Positives = 112/303 (36%), Gaps = 46/303 (15%)
Query: 87 EPIAFDGSRMSKEEDSIWFRPTLLQDSGLYACVIRNSTYCMKVSISLTVGENDTGLCYNS 146
+PI + S + + L +D G Y C+ N+ + S +TV E + +
Sbjct: 483 QPIQYARSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKS----SR 538
Query: 147 KMKYFEKAELSKS---------KEISCRDIEDFLLPTR-----EPEILWYKECRTKTWRP 192
K +Y SK ++ D + + PE++W
Sbjct: 539 KSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESE 598
Query: 193 SIVFKR----DTLLIREVREDDIGNYTCELKYGGFVVRRTTELTVTAPLTDKPPKLLYPM 248
F++ +L I+EV +D G YTCE VR LTV P P +
Sbjct: 599 DFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFI--- 655
Query: 249 ESKLTIQETQLGDSANLTCRAFFGYSGDVSPLIYWMK-GEKFIEDLDENRVWESD---IR 304
SK LG S ++C +GD P ++W++ G+ +D V +++
Sbjct: 656 -SKPRSVTASLGQSVLISC----AIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTL 710
Query: 305 ILKE----HLGEQEVSISLIVDSVEEGDLGNYSCYVENGNGRRHASVLLHKRELMYTVEL 360
+LK+ H G+ E+ + + +G SC V A L RE +L
Sbjct: 711 VLKKVQPWHAGQYEILL--------KNRVGECSCQVSLMLQNSSARALPRGREPASCEDL 762
Query: 361 AGG 363
GG
Sbjct: 763 CGG 765
Score = 47.0 bits (110), Expect = 6e-05
Identities = 51/209 (24%), Positives = 84/209 (40%), Gaps = 56/209 (26%)
Query: 176 EPEILWYKECRTKTWRPSIVFK---RDT--LLIREVREDDIGNYTCELKYGGFVVRRTTE 230
EP++ W++ + T + R T L+I V E+D G YTCE G + T E
Sbjct: 61 EPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVE 120
Query: 231 LTVTA--------PLTDK---------------------PPKLLYPMESKLTIQETQLGD 261
LTV P+ K PPK + ++ ++E Q+G
Sbjct: 121 LTVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKFATKL-GRVVVKEGQMG- 178
Query: 262 SANLTCRAFFGYSGDVSPLIYWMKGEKFIEDLDENRVWESD-IRILKEHLGEQEVSISLI 320
+C+ +G P + W+KG ++ V E + +++L+ H
Sbjct: 179 --RFSCK----ITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIH----------- 221
Query: 321 VDSVEEGDLGNYSCYVENGNGRRHASVLL 349
V + D+G Y+C V NG+G+ S L
Sbjct: 222 --GVNQDDVGVYTCLVVNGSGKASMSAEL 248
>gi|116008188 myosin light chain kinase isoform 2 [Homo sapiens]
Length = 1845
Score = 50.4 bits (119), Expect = 5e-06
Identities = 68/303 (22%), Positives = 112/303 (36%), Gaps = 46/303 (15%)
Query: 87 EPIAFDGSRMSKEEDSIWFRPTLLQDSGLYACVIRNSTYCMKVSISLTVGENDTGLCYNS 146
+PI + S + + L +D G Y C+ N+ + S +TV E + +
Sbjct: 483 QPIQYARSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKS----SR 538
Query: 147 KMKYFEKAELSKS---------KEISCRDIEDFLLPTR-----EPEILWYKECRTKTWRP 192
K +Y SK ++ D + + PE++W
Sbjct: 539 KSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESE 598
Query: 193 SIVFKR----DTLLIREVREDDIGNYTCELKYGGFVVRRTTELTVTAPLTDKPPKLLYPM 248
F++ +L I+EV +D G YTCE VR LTV P P +
Sbjct: 599 DFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFI--- 655
Query: 249 ESKLTIQETQLGDSANLTCRAFFGYSGDVSPLIYWMK-GEKFIEDLDENRVWESD---IR 304
SK LG S ++C +GD P ++W++ G+ +D V +++
Sbjct: 656 -SKPRSVTASLGQSVLISC----AIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTL 710
Query: 305 ILKE----HLGEQEVSISLIVDSVEEGDLGNYSCYVENGNGRRHASVLLHKRELMYTVEL 360
+LK+ H G+ E+ + + +G SC V A L RE +L
Sbjct: 711 VLKKVQPWHAGQYEILL--------KNRVGECSCQVSLMLQNSSARALPRGREPASCEDL 762
Query: 361 AGG 363
GG
Sbjct: 763 CGG 765
Score = 47.0 bits (110), Expect = 6e-05
Identities = 51/209 (24%), Positives = 84/209 (40%), Gaps = 56/209 (26%)
Query: 176 EPEILWYKECRTKTWRPSIVFK---RDT--LLIREVREDDIGNYTCELKYGGFVVRRTTE 230
EP++ W++ + T + R T L+I V E+D G YTCE G + T E
Sbjct: 61 EPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVE 120
Query: 231 LTVTA--------PLTDK---------------------PPKLLYPMESKLTIQETQLGD 261
LTV P+ K PPK + ++ ++E Q+G
Sbjct: 121 LTVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKFATKL-GRVVVKEGQMG- 178
Query: 262 SANLTCRAFFGYSGDVSPLIYWMKGEKFIEDLDENRVWESD-IRILKEHLGEQEVSISLI 320
+C+ +G P + W+KG ++ V E + +++L+ H
Sbjct: 179 --RFSCK----ITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIH----------- 221
Query: 321 VDSVEEGDLGNYSCYVENGNGRRHASVLL 349
V + D+G Y+C V NG+G+ S L
Sbjct: 222 --GVNQDDVGVYTCLVVNGSGKASMSAEL 248
>gi|193083163 roundabout, axon guidance receptor, homolog 2 isoform
ROBO2a [Homo sapiens]
Length = 1394
Score = 50.4 bits (119), Expect = 5e-06
Identities = 64/276 (23%), Positives = 110/276 (39%), Gaps = 51/276 (18%)
Query: 98 KEEDSIWFRPTLLQDSGLYACVIRNSTYCMKVSISLTVGENDTGLCYNSKMKYFEKAELS 157
K++ ++ + T+ D G Y C+ N M+ S +LTV + ++ +
Sbjct: 289 KDDYTLRIKKTMSTDEGTYMCIAENRVGKMEASATLTV---------RAPPQFVVRP--- 336
Query: 158 KSKEISCRDIEDFLLPTR---EPEILWYKECRTKTWRPS---------IVFKRDTLLIRE 205
+ + ++ F T+ +P + W KE P+ V L I
Sbjct: 337 RDQIVAQGRTVTFPCETKGNPQPAVFWQKEGSQNLLFPNQPQQPNSRCSVSPTGDLTITN 396
Query: 206 VREDDIGNYTCE-LKYGGFVVRRTTELTVTAPLTDKPPKLLY--PMESKLTIQETQLGDS 262
++ D G Y C+ L G ++ + +L VT LTD+PP ++ P L + T L
Sbjct: 397 IQRSDAGYYICQALTVAGSILAKA-QLEVTDVLTDRPPPIILQGPANQTLAVDGTAL--- 452
Query: 263 ANLTCRAFFGYSGDVSPLIYWMKGEKFIEDLDENRVWESDIRILKEHLGEQEVSISLIVD 322
L C+A +GD P+I W+K E F D R + G +L +
Sbjct: 453 --LKCKA----TGDPLPVISWLK-EGFTFP-------GRDPRATIQEQG------TLQIK 492
Query: 323 SVEEGDLGNYSCYVENGNGRRHASVLLHKRELMYTV 358
++ D G Y+C + +G S +L E T+
Sbjct: 493 NLRISDTGTYTCVATSSSGETSWSAVLDVTESGATI 528
Score = 38.1 bits (87), Expect = 0.028
Identities = 43/178 (24%), Positives = 65/178 (36%), Gaps = 29/178 (16%)
Query: 176 EPEILWYKE-CRTKTWRPSIVFKRDTLLIREVREDDIGNYTCELKYGGFVVRRTTELTVT 234
EP I W K+ R I + L+I R+ D G YTC G +V
Sbjct: 178 EPTIYWKKDKVRIDDKEERISIRGGKLMISNTRKSDAGMYTC---VGTNMVGERDSDPAE 234
Query: 235 APLTDKPPKLLYPMESKLTIQETQLGDSANLTCRAFFGYSGDVSPLIYWMKGEKFIEDLD 294
+ ++P L P+ +++ ++E ++ C+ GD P + W K + DL
Sbjct: 235 LTVFERPTFLRRPI-NQVVLEE----EAVEFRCQV----QGDPQPTVRWKKDDA---DLP 282
Query: 295 ENRVWESDIRILKEHLGEQEVSISLIVDSVEEGDLGNYSCYVENGNGRRHASVLLHKR 352
R D +L + D G Y C EN G+ AS L R
Sbjct: 283 RGRYDIKD-------------DYTLRIKKTMSTDEGTYMCIAENRVGKMEASATLTVR 327
Score = 33.1 bits (74), Expect = 0.89
Identities = 64/301 (21%), Positives = 110/301 (36%), Gaps = 62/301 (20%)
Query: 43 VLVGEPVRIKCALFYGYIRTNYSLAQSAGLSLMWYKSSGPGDFEEPIAFDGSRMSKEEDS 102
V GEP ++C G+ ++ W K D +E R+S
Sbjct: 160 VAAGEPAILECQPPRGHPEP----------TIYWKKDKVRIDDKE------ERISIRGGK 203
Query: 103 IWFRPTLLQDSGLYACVIRNSTYCMKVSISLTVGENDTGLCYNSKMKYFEKAELSKSKEI 162
+ T D+G+Y CV N VGE D+ +++ FE+ + + I
Sbjct: 204 LMISNTRKSDAGMYTCVGTNM-----------VGERDSD---PAELTVFERPTFLR-RPI 248
Query: 163 SCRDIEDFLLPTR-------EPEILWYKECRTKTWRPSIVFKRD-TLLIREVREDDIGNY 214
+ +E+ + R +P + W K+ R K D TL I++ D G Y
Sbjct: 249 NQVVLEEEAVEFRCQVQGDPQPTVRWKKDDADLP-RGRYDIKDDYTLRIKKTMSTDEGTY 307
Query: 215 TCELKYGGFVVRRTTELTVTAPLTDK-PPKLLYPMESKLTIQETQLGDSANLTCRAFFGY 273
C R ++ +A LT + PP+ + ++ Q G + C
Sbjct: 308 MC------IAENRVGKMEASATLTVRAPPQFVVRPRDQIVAQ----GRTVTFPCET---- 353
Query: 274 SGDVSPLIYWMKGEKFIEDLDENRVWESDIRILKEHLGEQEVSISLIVDSVEEGDLGNYS 333
G+ P ++W K E L N+ + + R G+ L + +++ D G Y
Sbjct: 354 KGNPQPAVFWQK-EGSQNLLFPNQPQQPNSRCSVSPTGD------LTITNIQRSDAGYYI 406
Query: 334 C 334
C
Sbjct: 407 C 407
Score = 30.4 bits (67), Expect = 5.8
Identities = 35/138 (25%), Positives = 49/138 (35%), Gaps = 33/138 (23%)
Query: 210 DIGNYTCELK-YGGFVVRRTTELTVTAPLTDKPPKLLYPMESKLTIQETQLGDSANLTCR 268
D G+Y C + Y G V R L V D T G+ A L C+
Sbjct: 120 DEGSYVCVARNYLGEAVSRNASLEVALLRDD--------FRQNPTDVVVAAGEPAILECQ 171
Query: 269 AFFGYSGDVSPLIYWMKGEKFIEDLDENRVWESDIRILKEHLGEQEVSI---SLIVDSVE 325
G+ P IYW K + I+D E+ +SI L++ +
Sbjct: 172 PPRGHP---EPTIYWKKDKVRIDD------------------KEERISIRGGKLMISNTR 210
Query: 326 EGDLGNYSCYVENGNGRR 343
+ D G Y+C N G R
Sbjct: 211 KSDAGMYTCVGTNMVGER 228
>gi|61888896 roundabout, axon guidance receptor, homolog 2 isoform
ROBO2b [Homo sapiens]
Length = 1378
Score = 50.4 bits (119), Expect = 5e-06
Identities = 64/276 (23%), Positives = 110/276 (39%), Gaps = 51/276 (18%)
Query: 98 KEEDSIWFRPTLLQDSGLYACVIRNSTYCMKVSISLTVGENDTGLCYNSKMKYFEKAELS 157
K++ ++ + T+ D G Y C+ N M+ S +LTV + ++ +
Sbjct: 273 KDDYTLRIKKTMSTDEGTYMCIAENRVGKMEASATLTV---------RAPPQFVVRP--- 320
Query: 158 KSKEISCRDIEDFLLPTR---EPEILWYKECRTKTWRPS---------IVFKRDTLLIRE 205
+ + ++ F T+ +P + W KE P+ V L I
Sbjct: 321 RDQIVAQGRTVTFPCETKGNPQPAVFWQKEGSQNLLFPNQPQQPNSRCSVSPTGDLTITN 380
Query: 206 VREDDIGNYTCE-LKYGGFVVRRTTELTVTAPLTDKPPKLLY--PMESKLTIQETQLGDS 262
++ D G Y C+ L G ++ + +L VT LTD+PP ++ P L + T L
Sbjct: 381 IQRSDAGYYICQALTVAGSILAKA-QLEVTDVLTDRPPPIILQGPANQTLAVDGTAL--- 436
Query: 263 ANLTCRAFFGYSGDVSPLIYWMKGEKFIEDLDENRVWESDIRILKEHLGEQEVSISLIVD 322
L C+A +GD P+I W+K E F D R + G +L +
Sbjct: 437 --LKCKA----TGDPLPVISWLK-EGFTFP-------GRDPRATIQEQG------TLQIK 476
Query: 323 SVEEGDLGNYSCYVENGNGRRHASVLLHKRELMYTV 358
++ D G Y+C + +G S +L E T+
Sbjct: 477 NLRISDTGTYTCVATSSSGETSWSAVLDVTESGATI 512
Score = 38.1 bits (87), Expect = 0.028
Identities = 43/178 (24%), Positives = 65/178 (36%), Gaps = 29/178 (16%)
Query: 176 EPEILWYKE-CRTKTWRPSIVFKRDTLLIREVREDDIGNYTCELKYGGFVVRRTTELTVT 234
EP I W K+ R I + L+I R+ D G YTC G +V
Sbjct: 162 EPTIYWKKDKVRIDDKEERISIRGGKLMISNTRKSDAGMYTC---VGTNMVGERDSDPAE 218
Query: 235 APLTDKPPKLLYPMESKLTIQETQLGDSANLTCRAFFGYSGDVSPLIYWMKGEKFIEDLD 294
+ ++P L P+ +++ ++E ++ C+ GD P + W K + DL
Sbjct: 219 LTVFERPTFLRRPI-NQVVLEE----EAVEFRCQV----QGDPQPTVRWKKDDA---DLP 266
Query: 295 ENRVWESDIRILKEHLGEQEVSISLIVDSVEEGDLGNYSCYVENGNGRRHASVLLHKR 352
R D +L + D G Y C EN G+ AS L R
Sbjct: 267 RGRYDIKD-------------DYTLRIKKTMSTDEGTYMCIAENRVGKMEASATLTVR 311
Score = 33.1 bits (74), Expect = 0.89
Identities = 64/301 (21%), Positives = 110/301 (36%), Gaps = 62/301 (20%)
Query: 43 VLVGEPVRIKCALFYGYIRTNYSLAQSAGLSLMWYKSSGPGDFEEPIAFDGSRMSKEEDS 102
V GEP ++C G+ ++ W K D +E R+S
Sbjct: 144 VAAGEPAILECQPPRGHPEP----------TIYWKKDKVRIDDKE------ERISIRGGK 187
Query: 103 IWFRPTLLQDSGLYACVIRNSTYCMKVSISLTVGENDTGLCYNSKMKYFEKAELSKSKEI 162
+ T D+G+Y CV N VGE D+ +++ FE+ + + I
Sbjct: 188 LMISNTRKSDAGMYTCVGTNM-----------VGERDSD---PAELTVFERPTFLR-RPI 232
Query: 163 SCRDIEDFLLPTR-------EPEILWYKECRTKTWRPSIVFKRD-TLLIREVREDDIGNY 214
+ +E+ + R +P + W K+ R K D TL I++ D G Y
Sbjct: 233 NQVVLEEEAVEFRCQVQGDPQPTVRWKKDDADLP-RGRYDIKDDYTLRIKKTMSTDEGTY 291
Query: 215 TCELKYGGFVVRRTTELTVTAPLTDK-PPKLLYPMESKLTIQETQLGDSANLTCRAFFGY 273
C R ++ +A LT + PP+ + ++ Q G + C
Sbjct: 292 MC------IAENRVGKMEASATLTVRAPPQFVVRPRDQIVAQ----GRTVTFPCET---- 337
Query: 274 SGDVSPLIYWMKGEKFIEDLDENRVWESDIRILKEHLGEQEVSISLIVDSVEEGDLGNYS 333
G+ P ++W K E L N+ + + R G+ L + +++ D G Y
Sbjct: 338 KGNPQPAVFWQK-EGSQNLLFPNQPQQPNSRCSVSPTGD------LTITNIQRSDAGYYI 390
Query: 334 C 334
C
Sbjct: 391 C 391
Score = 30.4 bits (67), Expect = 5.8
Identities = 35/138 (25%), Positives = 49/138 (35%), Gaps = 33/138 (23%)
Query: 210 DIGNYTCELK-YGGFVVRRTTELTVTAPLTDKPPKLLYPMESKLTIQETQLGDSANLTCR 268
D G+Y C + Y G V R L V D T G+ A L C+
Sbjct: 104 DEGSYVCVARNYLGEAVSRNASLEVALLRDD--------FRQNPTDVVVAAGEPAILECQ 155
Query: 269 AFFGYSGDVSPLIYWMKGEKFIEDLDENRVWESDIRILKEHLGEQEVSI---SLIVDSVE 325
G+ P IYW K + I+D E+ +SI L++ +
Sbjct: 156 PPRGHP---EPTIYWKKDKVRIDD------------------KEERISIRGGKLMISNTR 194
Query: 326 EGDLGNYSCYVENGNGRR 343
+ D G Y+C N G R
Sbjct: 195 KSDAGMYTCVGTNMVGER 212
>gi|19743806 roundabout 1 isoform b [Homo sapiens]
Length = 1612
Score = 49.7 bits (117), Expect = 9e-06
Identities = 59/249 (23%), Positives = 93/249 (37%), Gaps = 47/249 (18%)
Query: 112 DSGLYACVIRN---STYCMKVSISLTVGENDTGLCYNSKMKYFEKAELSKSKEISCRDIE 168
D G+Y CV RN S+ + + +D + M + + + C+
Sbjct: 102 DEGVYVCVARNYLGEAVSHNASLEVAILRDDFRQNPSDVM-----VAVGEPAVMECQ--- 153
Query: 169 DFLLPTR---EPEILWYKECRTKTWRPS-IVFKRDTLLIREVREDDIGNYTCELKYGGFV 224
P R EP I W K+ + I + L+I R+ D G Y C G +
Sbjct: 154 ----PPRGHPEPTISWKKDGSPLDDKDERITIRGGKLMITYTRKSDAGKYVC---VGTNM 206
Query: 225 VRRTTELTVTAPLTDKPPKLLYPMESKLTIQETQLGDSANLTCRAFFGYSGDVSPLIYWM 284
V + ++P + P +T+ DSA C A GD P + W
Sbjct: 207 VGERESEVAELTVLERPSFVKRPSNLAVTVD-----DSAEFKCEA----RGDPVPTVRWR 257
Query: 285 KGEKFIEDLDENRVWESDIRILKEHLGEQEVSISLIVDSVEEGDLGNYSCYVENGNGRRH 344
K D+ + +S I +H +L + V GD+G+Y+C EN G+
Sbjct: 258 K--------DDGELPKSRYEIRDDH--------TLKIRKVTAGDMGSYTCVAENMVGKAE 301
Query: 345 ASVLLHKRE 353
AS L +E
Sbjct: 302 ASATLTVQE 310
Score = 43.5 bits (101), Expect = 7e-04
Identities = 60/274 (21%), Positives = 104/274 (37%), Gaps = 45/274 (16%)
Query: 98 KEEDSIWFRPTLLQDSGLYACVIRNSTYCMKVSISLTVGENDTGLCYNSKMKYFEKAELS 157
+++ ++ R D G Y CV N + S +LTV E + + L
Sbjct: 271 RDDHTLKIRKVTAGDMGSYTCVAENMVGKAEASATLTVQEPPHFVVKPRD----QVVALG 326
Query: 158 KSKEISCRDIEDFLLPTREPEILWYKECRTK---TWRPS------IVFKRDTLLIREVRE 208
++ C + +P I W +E +++P V + L I V+
Sbjct: 327 RTVTFQCEATGN-----PQPAIFWRREGSQNLLFSYQPPQSSSRFSVSQTGDLTITNVQR 381
Query: 209 DDIGNYTCE-LKYGGFVVRRTTELTVTAPLTDKPPKLLY--PMESKLTIQETQLGDSANL 265
D+G Y C+ L G ++ + L VT + D+PP ++ P+ + + T + L
Sbjct: 382 SDVGYYICQTLNVAGSIITKAY-LEVTDVIADRPPPVIRQGPVNQTVAVDGTFV-----L 435
Query: 266 TCRAFFGYSGDVSPLIYWMKGEKFIEDLDENRVWESDIRILKEHLGEQEVSISLIVDSVE 325
+C A +G P I W K D V D RI + G ++ + +
Sbjct: 436 SCVA----TGSPVPTILWRK--------DGVLVSTQDSRIKQLENGVLQIRYAKL----- 478
Query: 326 EGDLGNYSCYVENGNGRRHASVLLHKRELMYTVE 359
GD G Y+C +G S + +E V+
Sbjct: 479 -GDTGRYTCIASTPSGEATWSAYIEVQEFGVPVQ 511
>gi|239755187 PREDICTED: similar to hemicentin 2 [Homo sapiens]
Length = 1215
Score = 49.7 bits (117), Expect = 9e-06
Identities = 61/241 (25%), Positives = 93/241 (38%), Gaps = 44/241 (18%)
Query: 112 DSGLYACVIRNSTYCMKVSISLTVGENDTGLCYNSKMKYFEKAELSKSKEISCRDIEDFL 171
D G Y CV N+ + S+ L V E + S + + E+ S S
Sbjct: 464 DGGRYQCVASNANGVTRASVWLLVREAPQVSIHTSSQHFSQGVEVKVSCSASG------- 516
Query: 172 LPTREPEILWYKECRTKTWRPSI-VFKRDTLLIREVREDDIGNYTCEL--KYGGFVVRRT 228
PT P I W +E + I V + TL+I+ V +D GNY+C+ + G T
Sbjct: 517 YPT--PHISWSRESQALQEDSRIHVDAQGTLIIQGVAPEDAGNYSCQATNEVG------T 568
Query: 229 TELTVTAPLTDKPPKLLYPMESKLTIQETQLGDSANLTCRAFFGYSGDVSPLIYWMKGEK 288
+ TVT TD P + + + +G+ A L C A SG P + W +G
Sbjct: 569 DQETVTLYYTDPP-----SVSAVNAVVLVAVGEEAVLVCEA----SGVPPPRVIWYRG-- 617
Query: 289 FIEDLDENRVWESDIRILKEHLGEQEVSISLIVDSVEEGDLGNYSCYVENGNGRRHASVL 348
+ ++ G S L + + +E D G Y+C N G A +
Sbjct: 618 -------------GLEMILAPEGSS--SGKLRIPAAQERDAGTYTCRAVNELGDASAEIQ 662
Query: 349 L 349
L
Sbjct: 663 L 663
Score = 38.1 bits (87), Expect = 0.028
Identities = 38/144 (26%), Positives = 53/144 (36%), Gaps = 31/144 (21%)
Query: 212 GNYTCELKYGGFVVRRTTELTVTAPLTDKPPKLLYPMESKLTIQETQLGDSANLTCRAFF 271
G Y C R ++ VT P PP+L+ +T+ G++A L+CR
Sbjct: 375 GTYECTAVSRAGTGRAKAQIVVTDP----PPQLV--PAPNVTVSP---GETAVLSCRV-- 423
Query: 272 GYSGDVSPLIYWMKGEKFIEDLDENRVWESDIRILKEHLGE--QEVSISLIVDSVEEGDL 329
+ + N W D R+L G Q +SL + + D
Sbjct: 424 ------------------LGEAPYNLTWVRDWRVLPASTGRVAQLADLSLEISGIIPTDG 465
Query: 330 GNYSCYVENGNGRRHASVLLHKRE 353
G Y C N NG ASV L RE
Sbjct: 466 GRYQCVASNANGVTRASVWLLVRE 489
Score = 34.3 bits (77), Expect = 0.40
Identities = 70/304 (23%), Positives = 99/304 (32%), Gaps = 51/304 (16%)
Query: 42 QVLVGEPVRIKCALFYGYIRTNYSLAQSAGLSLMWYKSSGPGDFEEPIAFDGSRMSKEED 101
+VL G+PV + C + G W K P GSR S D
Sbjct: 778 RVLEGQPVSLPCIVLAGRPLPERH----------WLKDGRPLP-------PGSRHSIRAD 820
Query: 102 -SIWFRPTLLQDSGLYACVIRNSTYCMKVSISLTVGENDTGLCYNSKMKYFEKAELSKSK 160
S+ L + +G Y+CV N+ + L V + A +
Sbjct: 821 GSLHLDRALQEHAGRYSCVATNTAGSQHRDVELVV---------QVPPRIHPTATHHITN 871
Query: 161 EISCRDIEDFLLPTREPEILWYKECRTKTWRPSI--VFKRDTLLIREVREDDIGNYTCEL 218
E + P I W KE T R V K TLLI + D G Y C
Sbjct: 872 EGVPASLPCVASGVPAPTITWTKETNALTSRGPHYNVSKEGTLLIAQPSAQDAGAYVCTA 931
Query: 219 KYGGFVVRRTTELTVTAPLTDKPPKLLYPMESKLTIQET-QLGDSANLTCRAFFGYSGDV 277
+ L+V T + + + +Q T + G+ L C A G
Sbjct: 932 TNTVGFSSQEMRLSVN---TKPRIHMNGSRNANVPLQVTAKAGEEVTLDCEA----KGSP 984
Query: 278 SPLIYWMKGEKFIEDLDENRVWESDIRILKEHLGEQEVSISLIVDSVEEGDLGNYSCYVE 337
PL+ W K + + + NR S SL + V+ GD G+Y C
Sbjct: 985 PPLVTWTKDSRPVPPI-TNRYGLLP-------------SGSLRLAQVQVGDSGHYECTAS 1030
Query: 338 NGNG 341
N G
Sbjct: 1031 NPAG 1034
Score = 32.7 bits (73), Expect = 1.2
Identities = 39/151 (25%), Positives = 57/151 (37%), Gaps = 28/151 (18%)
Query: 200 TLLIREVREDDIGNYTCELKYGGFVVRRTTELTVTAPLTDKPPKLLYPMESKLTIQETQL 259
+L I + D G Y C V R + L V + P++ S Q
Sbjct: 454 SLEISGIIPTDGGRYQCVASNANGVTRASVWLLVR-----EAPQVSIHTSS----QHFSQ 504
Query: 260 GDSANLTCRAFFGYSGDVSPLIYWMKGEKFIEDLDENRVWESDIRILKEHLGEQEVSISL 319
G ++C A SG +P I W + E++ + D RI + G +L
Sbjct: 505 GVEVKVSCSA----SGYPTPHISWSR---------ESQALQEDSRIHVDAQG------TL 545
Query: 320 IVDSVEEGDLGNYSCYVENGNGRRHASVLLH 350
I+ V D GNYSC N G +V L+
Sbjct: 546 IIQGVAPEDAGNYSCQATNEVGTDQETVTLY 576
>gi|239749684 PREDICTED: hemicentin 2 [Homo sapiens]
Length = 5065
Score = 49.7 bits (117), Expect = 9e-06
Identities = 61/241 (25%), Positives = 93/241 (38%), Gaps = 44/241 (18%)
Query: 112 DSGLYACVIRNSTYCMKVSISLTVGENDTGLCYNSKMKYFEKAELSKSKEISCRDIEDFL 171
D G Y CV N+ + S+ L V E + S + + E+ S S
Sbjct: 581 DGGRYQCVASNANGVTRASVWLLVREAPQVSIHTSSQHFSQGVEVKVSCSASG------- 633
Query: 172 LPTREPEILWYKECRTKTWRPSI-VFKRDTLLIREVREDDIGNYTCEL--KYGGFVVRRT 228
PT P I W +E + I V + TL+I+ V +D GNY+C+ + G T
Sbjct: 634 YPT--PHISWSRESQALQEDSRIHVDAQGTLIIQGVAPEDAGNYSCQATNEVG------T 685
Query: 229 TELTVTAPLTDKPPKLLYPMESKLTIQETQLGDSANLTCRAFFGYSGDVSPLIYWMKGEK 288
+ TVT TD P + + + +G+ A L C A SG P + W +G
Sbjct: 686 DQETVTLYYTDPP-----SVSAVNAVVLVAVGEEAVLVCEA----SGVPPPRVIWYRG-- 734
Query: 289 FIEDLDENRVWESDIRILKEHLGEQEVSISLIVDSVEEGDLGNYSCYVENGNGRRHASVL 348
+ ++ G S L + + +E D G Y+C N G A +
Sbjct: 735 -------------GLEMILAPEGSS--SGKLRIPAAQERDAGTYTCRAVNELGDASAEIQ 779
Query: 349 L 349
L
Sbjct: 780 L 780
Score = 47.0 bits (110), Expect = 6e-05
Identities = 51/199 (25%), Positives = 75/199 (37%), Gaps = 41/199 (20%)
Query: 176 EPEILWYKECRTKTWRPS--IVFKRDTLLIREVREDDIGNYTCELKYGGFVVRRTTELTV 233
EP I W K+ + + + LL++ + D G YTC + RR LT+
Sbjct: 4066 EPNITWDKDGQPVSGAEGKFTIQPSGELLVKNLEGQDAGTYTCTAENAVGRARRRVHLTI 4125
Query: 234 TAPLTDKPPKLLYPMESKLTIQET-QLGDSANLTCRAFFGYSGDVSPLIYWMKGEKFIED 292
L+ P+ + L + +LGD L C A G +P I W +
Sbjct: 4126 ----------LVLPVFTTLPGDRSLRLGDRLWLRCAA----RGSPTPRIGWTVND----- 4166
Query: 293 LDENRVWESDIRILKEHLGEQEVSISLIVDSVEEGDLGNYSCYVENGNGRRHASVLLHKR 352
R + E + EQ+ +L +V D G Y C+ EN GR A +H +
Sbjct: 4167 -----------RPVTEGVSEQDGGSTLQRAAVSREDSGTYVCWAENRVGRTQAVSFVHVK 4215
Query: 353 E--------LMYTVELAGG 363
E Y VE GG
Sbjct: 4216 EAPVLQGEAFSYLVEPVGG 4234
Score = 45.8 bits (107), Expect = 1e-04
Identities = 63/238 (26%), Positives = 84/238 (35%), Gaps = 37/238 (15%)
Query: 113 SGLYACVIRNSTYCMKVSISLTVGENDTGLCYNSKMKYFEKAELSKSKEISCRDIEDFLL 172
+G Y C RNS + LTV + S ++ + E+ E S +
Sbjct: 3922 AGRYTCSARNSAGVAHKHVFLTVQASPVVKPLPSVVRAVAEEEVLLPCEASG-------I 3974
Query: 173 PTREPEILWYKE-CRTKTWRPSIVFKRDTLLIREVREDDIGNYTCELKYGGFVVRRTTEL 231
P P I W KE T + V L I +D GNY C K T L
Sbjct: 3975 P--RPTITWQKEGLNVATGVSTQVLPGGQLRIAHASPEDAGNYLCIAKNSAGSAMGKTRL 4032
Query: 232 TVTAPLTDKPPKLLYPMESKLTIQETQLGDSANLTCRAFFGYSGDVSPLIYWMKGEKFIE 291
V P +E+ L T G A L C+A G P I W
Sbjct: 4033 VVQVPPV---------IENGLPDLSTTEGSHAFLPCKA----RGSPEPNITW-------- 4071
Query: 292 DLDENRVWESDIRILKEHLGEQEVSISLIVDSVEEGDLGNYSCYVENGNGRRHASVLL 349
D D V ++ + + GE L+V ++E D G Y+C EN GR V L
Sbjct: 4072 DKDGQPVSGAEGKFTIQPSGE------LLVKNLEGQDAGTYTCTAENAVGRARRRVHL 4123
Score = 42.4 bits (98), Expect = 0.001
Identities = 57/236 (24%), Positives = 92/236 (38%), Gaps = 43/236 (18%)
Query: 110 LQDSGLYACVIRNSTYCMKVSISLTVGENDTGLCYNSKMKYFEKAELSKSKEISCRDIED 169
L DSG+Y C N+ + + L+V + + + A L + + + E
Sbjct: 3000 LSDSGMYTCEALNAAGRDQKLVQLSVLVPPA---FRQAPRGPQDAVLVRVGDKAVLSCET 3056
Query: 170 FLLPTREPEILWYKECRTKTWRPSIVFKRDTLL-------IREVREDDIGNYTCELKYGG 222
LP EP + WYK+ +P ++ +R L I+E + D G Y+C++
Sbjct: 3057 DALP--EPTVTWYKD-----GQPLVLAQRTQALRGGQRLEIQEAQVSDKGLYSCKVSNVA 3109
Query: 223 FVVRRTTELTVTAPLTDKPPKLLYPMESKLTIQETQLGDSANLTCRAFFGYSGDVSPLIY 282
RT LTV P T + PK T+ + G LTC SG +P +
Sbjct: 3110 GEAVRTFTLTVQVPPTFENPK-------TETVSQV-AGSPLVLTC----DVSGVPAPTVT 3157
Query: 283 WMKGEKFIEDLDENRVWESDIRILKEHLGEQEVSISLIVDSVEEGDLGNYSCYVEN 338
W+K D V S + + G ++S ++ G Y+C EN
Sbjct: 3158 WLK--------DRMPVESSAVHGVVSRGGRLQLS------RLQPAQAGTYTCVAEN 3199
Score = 39.7 bits (91), Expect = 0.010
Identities = 63/253 (24%), Positives = 93/253 (36%), Gaps = 53/253 (20%)
Query: 43 VLVGEPVRIKCALFYGYIRTNYSLAQSAGLSLMWYKSSGPGDFEEPIAFDGSRMSKEEDS 102
VLV PVR+ C N + A S +LMW K P P G ++
Sbjct: 1989 VLVNTPVRLTC---------NATGAPSP--TLMWLKDGNP---VSPAGTPGLQVFPGGRV 2034
Query: 103 IWFRPTLLQDSGLYACVIRNSTYCMKVSISLTVGENDTGLCYNSKMKYFEKAELSKSKEI 162
+ DSG Y+CV ++ VGE+ + M + L + +
Sbjct: 2035 LTLASARASDSGRYSCVAVSA-----------VGEDRQDVVLQVHMP---PSILGEELNV 2080
Query: 163 SCRDIEDFLLPTRE-----PEILWYKECRTKTWRPSIVFKRDTLLIREVRED--DIGNYT 215
S E L + P + W+K+ R RP + D L++ R D D G+YT
Sbjct: 2081 SVVANESVALECQSHAMPPPVLSWWKDGRPLEPRPGVHLSADKALLQVDRADVWDAGHYT 2140
Query: 216 CE-LKYGGFVVRRTTELTVTAPLTDKPPKLLYPMESK--LTIQETQLGDSANLTCRAFFG 272
CE L G + AP ++P+ LT++E G +L+C
Sbjct: 2141 CEALNQAGHSEKHYNLNVWVAP--------VFPLRESHTLTVRE---GHPTSLSCEC--- 2186
Query: 273 YSGDVSPLIYWMK 285
G P I W K
Sbjct: 2187 -RGVPFPKISWRK 2198
Score = 38.1 bits (87), Expect = 0.028
Identities = 38/144 (26%), Positives = 53/144 (36%), Gaps = 31/144 (21%)
Query: 212 GNYTCELKYGGFVVRRTTELTVTAPLTDKPPKLLYPMESKLTIQETQLGDSANLTCRAFF 271
G Y C R ++ VT P PP+L+ +T+ G++A L+CR
Sbjct: 492 GTYECTAVSRAGTGRAKAQIVVTDP----PPQLV--PAPNVTVSP---GETAVLSCRV-- 540
Query: 272 GYSGDVSPLIYWMKGEKFIEDLDENRVWESDIRILKEHLGE--QEVSISLIVDSVEEGDL 329
+ + N W D R+L G Q +SL + + D
Sbjct: 541 ------------------LGEAPYNLTWVRDWRVLPASTGRVAQLADLSLEISGIIPTDG 582
Query: 330 GNYSCYVENGNGRRHASVLLHKRE 353
G Y C N NG ASV L RE
Sbjct: 583 GRYQCVASNANGVTRASVWLLVRE 606
Score = 37.7 bits (86), Expect = 0.036
Identities = 43/148 (29%), Positives = 56/148 (37%), Gaps = 33/148 (22%)
Query: 200 TLLIREVREDDIGNYTCELKYGGFVVRRTTELTVTAPLTDKPPKLLYPMESKLTIQETQL 259
TL I +V+ D G +TC V R L V P +L P+E + + +
Sbjct: 3368 TLRISKVQLADAGIFTCVAASPAGVADRNFTLQVQVP------PVLEPVEFQNDVVVVR- 3420
Query: 260 GDSANLTCRAFFGYSGDVSPLIYWMK-GEKFIEDLDENRVWESDIRILKEHLGEQEVSIS 318
G L C A G PL+ WMK GE + E S
Sbjct: 3421 GSLVELPCEA----RGVPLPLVSWMKDGEPLLSQ-------------------SLEQGPS 3457
Query: 319 LIVDSVEEGDLGNYSCYV--ENGNGRRH 344
L +++V GD G YSC E G RRH
Sbjct: 3458 LQLEAVGAGDSGTYSCVAVSEAGEARRH 3485
Score = 37.7 bits (86), Expect = 0.036
Identities = 45/177 (25%), Positives = 73/177 (41%), Gaps = 35/177 (19%)
Query: 177 PEILWYKE---CRTKTWRPSIVFKRDTLLIREVREDDIGNYTCELKYGGFVVRRTTELTV 233
P+I W K+ R R + + +L I DD G Y C + V ++ L +
Sbjct: 4248 PDIHWIKDGLPLRGSHLRHQL--QNGSLTIHRTERDDAGRYQCLAENEMGVAKKVVILVL 4305
Query: 234 -TAPLTDKPPKLLYPMESKLTIQETQLGDSANLTCRAFFGYSGDVSPLIYWMKGEKFIED 292
+AP+ P+ +T++ GD L C+A +G+ +P I W++ +
Sbjct: 4306 QSAPVFQVEPQ-------DMTVRS---GDDVALRCQA----TGEPTPTIEWLQAG---QP 4348
Query: 293 LDENRVWESDIRILKEHLGEQEVSISLIVDSVEEGDLGNYSCYVENGNGRRHASVLL 349
L +R +R L + SL +++VE GD G Y C N G A L
Sbjct: 4349 LRASR----RLRTLPDG--------SLWLENVETGDAGTYDCVAHNLLGSATARAFL 4393
Score = 36.2 bits (82), Expect = 0.11
Identities = 68/299 (22%), Positives = 114/299 (38%), Gaps = 56/299 (18%)
Query: 87 EPIAFDGSRMSKEEDSIWFRPT--LLQDSGLYACVIRNST------YCMKVSISLTV-GE 137
+P+ G + +ED R T + D G Y CV + + ++V T+ G
Sbjct: 1447 QPVLPGGPHLQVQEDGQVLRITGSHVGDEGRYQCVAFSPAGQQARDFQLRVHAPPTIWGS 1506
Query: 138 NDTGLCYNSKMKYFEKAELSKSK-EISCRDIEDFLLPTREPEILWYKECRTKTWRPSIVF 196
N+TG E A + ++ C E +PT P I W+K+ +V+
Sbjct: 1507 NETG----------EVAVMEDHLVQLLC---EARGVPT--PNITWFKDGALLPTSTKVVY 1551
Query: 197 KRD--TLLIREVREDDIGNYTCELKYGGFVVRRTTELTVTAPLTDKPPKLLYPMESKLTI 254
R L + + D G YTC+ + T L V P T + + +
Sbjct: 1552 TRGGRQLQLGRAQSSDAGVYTCKASNAVGAAEKATRLDVYVPPT------IEGAGGRPYV 1605
Query: 255 QETQLGDSANLTCRAFFGYSGDVSPLIYWMKGEKFIEDLDENRVWESDIRILKEHLGEQE 314
+ G L C A G SP + W + + +E+R+ E+D +L+
Sbjct: 1606 VKAVAGRPVALECVA----RGHPSPTLSWHHEGLPVAESNESRL-ETDGSVLR------- 1653
Query: 315 VSISLIVDSVEEGDLGNYSCYVENGNGRRHASVLLHKRELMYTVEL--AGGLGAILLLL 371
++S E G YSC + G +VL + E+ +L A GLG + ++
Sbjct: 1654 ------LESPGEASSGLYSCVASSPAGE---AVLQYSVEVQVPPQLLVAEGLGQVTTIV 1703
Score = 34.7 bits (78), Expect = 0.31
Identities = 59/258 (22%), Positives = 91/258 (35%), Gaps = 46/258 (17%)
Query: 100 EDSIWFRPTLLQDSGLYACVIRNSTYCMKVSISLTVGENDTGLCYNSKMKYFEKAELSKS 159
+ S+ F D+G Y C NS + L V E ++ E S
Sbjct: 1166 QGSVHFAAIRTSDAGRYRCEASNSAGVDAWEVELRVLEPP----------HWGADETSGL 1215
Query: 160 KEISCRDIEDFLLPTR---EPEILWYKECRTKTW--RPSI-VFKRDTLLIREVREDDIGN 213
E + P R +P++ W K ++ +P + V + +L + V D G+
Sbjct: 1216 LERVAGENASLPCPARGTPKPQVTWRKGPSSEPLHGQPGVAVLEEGSLFLASVSPADSGD 1275
Query: 214 YTCELKYGGFVVRRTTELTVTAPLTDKPPKLLYPMESKLTIQETQLGDSANLTCRAFFGY 273
Y C+ R +L V P + + + + G S L C A
Sbjct: 1276 YECQATNEVGSTSRRAKLVVYVPPSIRE-------DGRKANVSGMAGQSLTLECDA---- 1324
Query: 274 SGDVSPLIYWMKGEKFIE----------DLDENRVWESDIRILKEHLGEQEVSISLIVDS 323
+G P I W+K + + DL +V R+L E SL
Sbjct: 1325 NGFPVPEIVWLKDAQLVGVPLGWAGYGWDLGWGQV--GGHRLLDE-------GQSLHFPR 1375
Query: 324 VEEGDLGNYSCYVENGNG 341
++EGD G YSC EN G
Sbjct: 1376 IQEGDSGLYSCRAENQAG 1393
Score = 34.3 bits (77), Expect = 0.40
Identities = 36/167 (21%), Positives = 55/167 (32%), Gaps = 25/167 (14%)
Query: 177 PEILWYKECRTKTWRPSIVFK--RDTLLIREVREDDIGNYTCELKYGGFVVRRTTELTVT 234
PE+ WYK+ + + + TL + R D G YTCE ++ +L+V
Sbjct: 2967 PEVTWYKDSQALSLGEEVFLLPGTHTLQLGRARLSDSGMYTCEALNAAGRDQKLVQLSVL 3026
Query: 235 APLTDKPPKLLYPMESKLTIQETQLGDSANLTCRAFFGYSGDVSPLIYWMKGEKFIEDLD 294
PP ++GD A L+C P + W K
Sbjct: 3027 V-----PPAFRQAPRGPQDAVLVRVGDKAVLSCET----DALPEPTVTWYK--------- 3068
Query: 295 ENRVWESDIRILKEHLGEQEVSISLIVDSVEEGDLGNYSCYVENGNG 341
+ +L + L + + D G YSC V N G
Sbjct: 3069 -----DGQPLVLAQRTQALRGGQRLEIQEAQVSDKGLYSCKVSNVAG 3110
Score = 33.1 bits (74), Expect = 0.89
Identities = 59/252 (23%), Positives = 91/252 (36%), Gaps = 55/252 (21%)
Query: 110 LQDSGLYACVIRNSTYCMKVSISLTVGENDTGLCYNSKMKYFEKAELSKSKEISCRDIED 169
L+D G+Y C N K ++L V + N + KA L E + +E
Sbjct: 1857 LRDEGIYTCAATNLAGESKREVALKV-----LVPPNIEPGPVNKAVL----ENASVTLEC 1907
Query: 170 FLLPTREPEILWYKECRTKTWRPSIVFKRD--TLLIREVREDDIGNYTC---------EL 218
P++ W+K + + + D L I + + D G+Y C EL
Sbjct: 1908 LASGVPPPDVSWFKGHQPVSSWMGVTVSVDGRVLRIEQAQLSDAGSYRCVASNVAGSTEL 1967
Query: 219 KYGGFVVRRTTELTVTA-PLTDKPPKLLYPMESKLTIQETQLGDSANLTCRAFFGYSGDV 277
+YG L V P PP L P+ + LTC A +G
Sbjct: 1968 RYG---------LRVNVPPRITLPPSLPGPV---------LVNTPVRLTCNA----TGAP 2005
Query: 278 SPLIYWMKGEKFIEDLDENRVWESDIRILKEHLGEQEVSISLIVDSVEEGDLGNYSCYVE 337
SP + W+K D N V + L+ G + ++++ S D G YSC
Sbjct: 2006 SPTLMWLK--------DGNPVSPAGTPGLQVFPGGRVLTLA----SARASDSGRYSCVAV 2053
Query: 338 NGNGRRHASVLL 349
+ G V+L
Sbjct: 2054 SAVGEDRQDVVL 2065
Score = 32.7 bits (73), Expect = 1.2
Identities = 39/151 (25%), Positives = 57/151 (37%), Gaps = 28/151 (18%)
Query: 200 TLLIREVREDDIGNYTCELKYGGFVVRRTTELTVTAPLTDKPPKLLYPMESKLTIQETQL 259
+L I + D G Y C V R + L V + P++ S Q
Sbjct: 571 SLEISGIIPTDGGRYQCVASNANGVTRASVWLLVR-----EAPQVSIHTSS----QHFSQ 621
Query: 260 GDSANLTCRAFFGYSGDVSPLIYWMKGEKFIEDLDENRVWESDIRILKEHLGEQEVSISL 319
G ++C A SG +P I W + E++ + D RI + G +L
Sbjct: 622 GVEVKVSCSA----SGYPTPHISWSR---------ESQALQEDSRIHVDAQG------TL 662
Query: 320 IVDSVEEGDLGNYSCYVENGNGRRHASVLLH 350
I+ V D GNYSC N G +V L+
Sbjct: 663 IIQGVAPEDAGNYSCQATNEVGTDQETVTLY 693
Score = 31.6 bits (70), Expect = 2.6
Identities = 62/268 (23%), Positives = 92/268 (34%), Gaps = 48/268 (17%)
Query: 92 DGSRMSKEEDSIWFRPT--LL------QDSGLYACVIRNST--YCMKVSISLTVGENDTG 141
DG +S E +P+ LL QD+G Y C N+ +V +++ V T
Sbjct: 4074 DGQPVSGAEGKFTIQPSGELLVKNLEGQDAGTYTCTAENAVGRARRRVHLTILVLPVFTT 4133
Query: 142 LCYNSKMKYFEKAELSKSKEISCRDIEDFLLPTREPEILWYKECRTKTWRPSIVFKRDTL 201
L + ++ ++ L + S PT P I W R T S TL
Sbjct: 4134 LPGDRSLRLGDRLWLRCAARGS---------PT--PRIGWTVNDRPVTEGVSEQDGGSTL 4182
Query: 202 LIREVREDDIGNYTCELKYGGFVVRRTTELTVTAPLTDKPPKLLYPMESKLTIQETQLGD 261
V +D G Y C + R + + K +L ++ +G
Sbjct: 4183 QRAAVSREDSGTYVC------WAENRVGRTQAVSFVHVKEAPVLQGEAFSYLVEP--VGG 4234
Query: 262 SANLTCRAFFGYSGDVSPLIYWMKGEKFIEDLDENRVWESDIRILKEHLGEQEVSISLIV 321
S L C GD P I+W+K + + HL Q + SL +
Sbjct: 4235 SIQLDCVV----RGDPVPDIHWIK---------------DGLPLRGSHLRHQLQNGSLTI 4275
Query: 322 DSVEEGDLGNYSCYVENGNGRRHASVLL 349
E D G Y C EN G V+L
Sbjct: 4276 HRTERDDAGRYQCLAENEMGVAKKVVIL 4303
Score = 31.2 bits (69), Expect = 3.4
Identities = 42/165 (25%), Positives = 59/165 (35%), Gaps = 31/165 (18%)
Query: 212 GNYTCELKYGGFVVRRTTELTVTAPLTDKPPKLLYPMESKLTIQETQLGDSANLTCRAFF 271
G YTCE V + +L + + PP++ P E + Q G A L C A
Sbjct: 2231 GTYTCECS--NVVGNSSQDLQLEVHV---PPQIAGPREPPTQVSVVQDG-VATLECNA-- 2282
Query: 272 GYSGDVSPLIYWMKGEKFIEDLDENRVWESDIRILKEHLGEQ--EVSISLIVDSVEEGDL 329
+G P + WE D + + LG Q SL V+ +
Sbjct: 2283 --TGKPPPTV----------------TWERDGQPVGAELGLQLQNQGQSLHVERAQAAHT 2324
Query: 330 GNYSCYVENGNGRRHASVLLHKRELMYTVELAGGLGAILLLLVCL 374
G YSC EN GR L ++ EL G L + + L
Sbjct: 2325 GRYSCVAENLAGRAERKFEL---SVLVPPELIGDLDPLTNITAAL 2366
Score = 30.8 bits (68), Expect = 4.4
Identities = 54/233 (23%), Positives = 75/233 (32%), Gaps = 31/233 (13%)
Query: 42 QVLVGEPVRIKCALFYGYIRTNYSLAQSAGLSLMWYKSSGPGDFEEPIAFDGSRMSKEED 101
+VL G+PV + C + G W K P GSR S D
Sbjct: 895 RVLEGQPVSLPCIVLAGRPLPERH----------WLKDGRPLP-------PGSRHSIRAD 937
Query: 102 -SIWFRPTLLQDSGLYACVIRNSTYCMKVSISLTVGENDTGLCYNSKMKYFEKAELSKSK 160
S+ L + +G Y+CV N+ + L V + A +
Sbjct: 938 GSLHLDRALQEHAGRYSCVATNTAGSQHRDVELVV---------QVPPRIHPTATHHITN 988
Query: 161 EISCRDIEDFLLPTREPEILWYKECRTKTWRPSI--VFKRDTLLIREVREDDIGNYTCEL 218
E + P I W KE T R V K TLLI + D G Y C
Sbjct: 989 EGVPASLPCVASGVPAPTITWTKETNALTSRGPHYNVSKEGTLLIAQPSAQDAGAYVCTA 1048
Query: 219 KYGGFVVRRTTELTVTAPLTDKPPKLLYPM--ESKLTIQETQLGDSANLTCRA 269
+ L+V K Y + L + + Q+GDS + C A
Sbjct: 1049 TNTVGFSSQEMRLSVNRLALSKYVWEEYGLLPSGSLRLAQVQVGDSGHYECTA 1101
Score = 29.6 bits (65), Expect = 9.9
Identities = 60/285 (21%), Positives = 108/285 (37%), Gaps = 44/285 (15%)
Query: 73 SLMWYKSSGP-GDFEEPIAFDGSRMSKEEDSIWFRPTLLQDSGLYACVIRNSTYCMKVSI 131
++ W++ P E+ G M K T QDSGLY+C+ N + +
Sbjct: 2383 AIRWFRGEEPVSPGEDTYLLAGGWMLK------MTQTQEQDSGLYSCLASNEAGEARRNF 2436
Query: 132 SLTVGENDTGLCYNSKMKYFEKAELSKSKEISCRDIEDFLLPTREPEILWYKECRTKTWR 191
S+ V + N ++ K ++ + C + +P++ W+K+ R
Sbjct: 2437 SVEVLVPPS--IENEDLEEVIKVLDGQTAHLMCN-----VTGHPQPKLTWFKDGRPLARG 2489
Query: 192 PSIVFKRDTLLIREVRED--DIGNYTCELKYGGFVVRRTTELTVTAPLTDKPPKLLYPME 249
+ D +L++ ++ + G+Y+C V +T ++ L P +L E
Sbjct: 2490 DAHHISPDGVLLQVLQANLSSAGHYSCIA--ANAVGEKTKHFQLSVLLA---PTILGGAE 2544
Query: 250 SKLTIQET-QLGDSANLTCRAFFGYSGDVSPLIYWMKGEKFIEDLDENRVWESDIRILKE 308
+ T + + +L C A SP I WMK E +I++L
Sbjct: 2545 DSADEEVTVTVNNPISLICEAL----AFPSPNITWMKDGAPFEA-------SRNIQLLPG 2593
Query: 309 HLGEQEVSISLIVDSVEEGDLGNYSCYVENGNGRR----HASVLL 349
G Q + + ++ D G Y+C V N G H VL+
Sbjct: 2594 THGLQ-------ILNAQKEDAGQYTCVVTNELGEAVKNYHVEVLI 2631
>gi|239743951 PREDICTED: hypothetical protein XP_002342997 [Homo
sapiens]
Length = 790
Score = 49.7 bits (117), Expect = 9e-06
Identities = 61/241 (25%), Positives = 93/241 (38%), Gaps = 44/241 (18%)
Query: 112 DSGLYACVIRNSTYCMKVSISLTVGENDTGLCYNSKMKYFEKAELSKSKEISCRDIEDFL 171
D G Y CV N+ + S+ L V E + S + + E+ S S
Sbjct: 580 DGGRYQCVASNANGVTRASVWLLVREAPQVSIHTSSQHFSQGVEVKVSCSASG------- 632
Query: 172 LPTREPEILWYKECRTKTWRPSI-VFKRDTLLIREVREDDIGNYTCEL--KYGGFVVRRT 228
PT P I W +E + I V + TL+I+ V +D GNY+C+ + G T
Sbjct: 633 YPT--PHISWSRESQALQEDSRIHVDAQGTLIIQGVAPEDAGNYSCQATNEVG------T 684
Query: 229 TELTVTAPLTDKPPKLLYPMESKLTIQETQLGDSANLTCRAFFGYSGDVSPLIYWMKGEK 288
+ TVT TD P + + + +G+ A L C A SG P + W +G
Sbjct: 685 DQETVTLYYTDPP-----SVSAVNAVVLVAVGEEAVLVCEA----SGVPPPRVIWYRG-- 733
Query: 289 FIEDLDENRVWESDIRILKEHLGEQEVSISLIVDSVEEGDLGNYSCYVENGNGRRHASVL 348
+ ++ G S L + + +E D G Y+C N G A +
Sbjct: 734 -------------GLEMILAPEGSS--SGKLRIPAAQERDAGTYTCRAVNELGDASAEIQ 778
Query: 349 L 349
L
Sbjct: 779 L 779
Score = 38.1 bits (87), Expect = 0.028
Identities = 38/144 (26%), Positives = 53/144 (36%), Gaps = 31/144 (21%)
Query: 212 GNYTCELKYGGFVVRRTTELTVTAPLTDKPPKLLYPMESKLTIQETQLGDSANLTCRAFF 271
G Y C R ++ VT P PP+L+ +T+ G++A L+CR
Sbjct: 491 GTYECTAVSRAGTGRAKAQIVVTDP----PPQLV--PAPNVTVSP---GETAVLSCRV-- 539
Query: 272 GYSGDVSPLIYWMKGEKFIEDLDENRVWESDIRILKEHLGE--QEVSISLIVDSVEEGDL 329
+ + N W D R+L G Q +SL + + D
Sbjct: 540 ------------------LGEAPYNLTWVRDWRVLPASTGRVAQLADLSLEISGIIPTDG 581
Query: 330 GNYSCYVENGNGRRHASVLLHKRE 353
G Y C N NG ASV L RE
Sbjct: 582 GRYQCVASNANGVTRASVWLLVRE 605
Score = 32.7 bits (73), Expect = 1.2
Identities = 39/151 (25%), Positives = 57/151 (37%), Gaps = 28/151 (18%)
Query: 200 TLLIREVREDDIGNYTCELKYGGFVVRRTTELTVTAPLTDKPPKLLYPMESKLTIQETQL 259
+L I + D G Y C V R + L V + P++ S Q
Sbjct: 570 SLEISGIIPTDGGRYQCVASNANGVTRASVWLLVR-----EAPQVSIHTSS----QHFSQ 620
Query: 260 GDSANLTCRAFFGYSGDVSPLIYWMKGEKFIEDLDENRVWESDIRILKEHLGEQEVSISL 319
G ++C A SG +P I W + E++ + D RI + G +L
Sbjct: 621 GVEVKVSCSA----SGYPTPHISWSR---------ESQALQEDSRIHVDAQG------TL 661
Query: 320 IVDSVEEGDLGNYSCYVENGNGRRHASVLLH 350
I+ V D GNYSC N G +V L+
Sbjct: 662 IIQGVAPEDAGNYSCQATNEVGTDQETVTLY 692
>gi|4506569 roundabout 1 isoform a [Homo sapiens]
Length = 1651
Score = 49.7 bits (117), Expect = 9e-06
Identities = 59/249 (23%), Positives = 93/249 (37%), Gaps = 47/249 (18%)
Query: 112 DSGLYACVIRN---STYCMKVSISLTVGENDTGLCYNSKMKYFEKAELSKSKEISCRDIE 168
D G+Y CV RN S+ + + +D + M + + + C+
Sbjct: 141 DEGVYVCVARNYLGEAVSHNASLEVAILRDDFRQNPSDVM-----VAVGEPAVMECQ--- 192
Query: 169 DFLLPTR---EPEILWYKECRTKTWRPS-IVFKRDTLLIREVREDDIGNYTCELKYGGFV 224
P R EP I W K+ + I + L+I R+ D G Y C G +
Sbjct: 193 ----PPRGHPEPTISWKKDGSPLDDKDERITIRGGKLMITYTRKSDAGKYVC---VGTNM 245
Query: 225 VRRTTELTVTAPLTDKPPKLLYPMESKLTIQETQLGDSANLTCRAFFGYSGDVSPLIYWM 284
V + ++P + P +T+ DSA C A GD P + W
Sbjct: 246 VGERESEVAELTVLERPSFVKRPSNLAVTVD-----DSAEFKCEA----RGDPVPTVRWR 296
Query: 285 KGEKFIEDLDENRVWESDIRILKEHLGEQEVSISLIVDSVEEGDLGNYSCYVENGNGRRH 344
K D+ + +S I +H +L + V GD+G+Y+C EN G+
Sbjct: 297 K--------DDGELPKSRYEIRDDH--------TLKIRKVTAGDMGSYTCVAENMVGKAE 340
Query: 345 ASVLLHKRE 353
AS L +E
Sbjct: 341 ASATLTVQE 349
Score = 43.5 bits (101), Expect = 7e-04
Identities = 60/274 (21%), Positives = 104/274 (37%), Gaps = 45/274 (16%)
Query: 98 KEEDSIWFRPTLLQDSGLYACVIRNSTYCMKVSISLTVGENDTGLCYNSKMKYFEKAELS 157
+++ ++ R D G Y CV N + S +LTV E + + L
Sbjct: 310 RDDHTLKIRKVTAGDMGSYTCVAENMVGKAEASATLTVQEPPHFVVKPRD----QVVALG 365
Query: 158 KSKEISCRDIEDFLLPTREPEILWYKECRTK---TWRPS------IVFKRDTLLIREVRE 208
++ C + +P I W +E +++P V + L I V+
Sbjct: 366 RTVTFQCEATGN-----PQPAIFWRREGSQNLLFSYQPPQSSSRFSVSQTGDLTITNVQR 420
Query: 209 DDIGNYTCE-LKYGGFVVRRTTELTVTAPLTDKPPKLLY--PMESKLTIQETQLGDSANL 265
D+G Y C+ L G ++ + L VT + D+PP ++ P+ + + T + L
Sbjct: 421 SDVGYYICQTLNVAGSIITKAY-LEVTDVIADRPPPVIRQGPVNQTVAVDGTFV-----L 474
Query: 266 TCRAFFGYSGDVSPLIYWMKGEKFIEDLDENRVWESDIRILKEHLGEQEVSISLIVDSVE 325
+C A +G P I W K D V D RI + G ++ + +
Sbjct: 475 SCVA----TGSPVPTILWRK--------DGVLVSTQDSRIKQLENGVLQIRYAKL----- 517
Query: 326 EGDLGNYSCYVENGNGRRHASVLLHKRELMYTVE 359
GD G Y+C +G S + +E V+
Sbjct: 518 -GDTGRYTCIASTPSGEATWSAYIEVQEFGVPVQ 550
>gi|126517478 peroxidasin homolog-like [Homo sapiens]
Length = 1463
Score = 49.7 bits (117), Expect = 9e-06
Identities = 43/174 (24%), Positives = 71/174 (40%), Gaps = 28/174 (16%)
Query: 176 EPEILWYKECRTKTWRPSI---VFKRDTLLIREVREDDIGNYTCELKYGGFVVRRTTELT 232
+PEI+W + VF TL+IR RE D G Y C + + + +
Sbjct: 262 KPEIIWIHNNHSLDLEDDTRLNVFDDGTLMIRNTRESDQGVYQCMARNSAGEAKTQSAML 321
Query: 233 VTAPLTDKPPKLLYPMESKLTIQETQLGDSANLTCRAFFGYSGDVSPLIYWMKGEKFIED 292
+ L KP ++ P ++ E +G S L C A +G PLI W + +
Sbjct: 322 RYSSLPAKPSFVIQPQDT-----EVLIGTSTTLECMA----TGHPHPLITWTRDNGL--E 370
Query: 293 LDENRVWESDIRILKEHLGEQEVSISLIVDSVEEGDLGNYSCYVENGNGRRHAS 346
LD +R H+ S L + ++ + D G ++C+ N +G A+
Sbjct: 371 LDGSR-----------HVA---TSSGLYLQNITQRDHGRFTCHANNSHGTVQAA 410
Score = 37.0 bits (84), Expect = 0.062
Identities = 59/287 (20%), Positives = 102/287 (35%), Gaps = 59/287 (20%)
Query: 74 LMWYKSSGPGDFEEPIAFDGSRMSKEED-SIWFRPTLLQDSGLYACVIRNSTYCMKVSIS 132
++W ++ D E D +R++ +D ++ R T D G+Y C+ RNS
Sbjct: 265 IIWIHNNHSLDLE-----DDTRLNVFDDGTLMIRNTRESDQGVYQCMARNS--------- 310
Query: 133 LTVGENDTGLCYNSKMKYFEKAELSKSKEISCRDIEDFL--------LPTREPE--ILWY 182
GE T S M + S I +D E + + T P I W
Sbjct: 311 --AGEAKT----QSAMLRYSSLPAKPSFVIQPQDTEVLIGTSTTLECMATGHPHPLITWT 364
Query: 183 KECRTKTWRPSIVFKRDTLLIREVREDDIGNYTCELKYGGFVVRRTTELTVTAPLTDKPP 242
++ + V L ++ + + D G +TC V+ + V A PP
Sbjct: 365 RDNGLELDGSRHVATSSGLYLQNITQRDHGRFTCHANNSHGTVQAAANIIVQA-----PP 419
Query: 243 KLLYPMESKLTIQETQLGDSANLTCRAFFGYSGDVSPLIYWMKGEKFIEDLDENRVWESD 302
+ + ++ ++E + C A G+ P+I W K + ++ V S
Sbjct: 420 QFTVTPKDQVVLEE----HAVEWLCEA----DGNPPPVIVWTKTGGQLPVEGQHTVLSSG 471
Query: 303 IRILKEHLGEQEVSISLIVDSVEEGDLGNYSCYVENGNGRRHASVLL 349
+L +D + D G Y C + G + SV L
Sbjct: 472 ---------------TLRIDRAAQHDQGQYECQAVSSLGVKKVSVQL 503
Score = 35.0 bits (79), Expect = 0.23
Identities = 53/251 (21%), Positives = 95/251 (37%), Gaps = 21/251 (8%)
Query: 74 LMWYKSSGPGDFEEPIAFDGSRMSKEEDSIWFRPTLLQDSGLYACVIRNSTYCMKVSISL 133
++W K+ G + +G ++ D G Y C +S KVS+ L
Sbjct: 450 IVWTKTGGQ------LPVEGQHTVLSSGTLRIDRAAQHDQGQYECQAVSSLGVKKVSVQL 503
Query: 134 TVGENDTGLCYNSKMKYFEKAELSKSKEISCRDIEDFLLPTREPEILWYKECRTKTWRPS 193
TV L +++ E+ K+ ISC + +P I W KE T
Sbjct: 504 TV--KPKALAVFTQLPQDTSVEVGKNINISCHAQGE-----PQPIITWNKEGVQITESGK 556
Query: 194 I-VFKRDTLLIREVREDDIGNYTCELKYGGFVVRRTTELTVTAPLTDKPPKLLYPMESKL 252
V TL I + D G Y C + + LTVTA + +ES +
Sbjct: 557 FHVDDEGTLTIYDAGFPDQGRYECVARNSFGLAVTNMFLTVTAIQGRQAGDDF--VESSI 614
Query: 253 TIQETQLGDSANLTCRAFFGY----SGDVSPLIYWMKGEKFIEDLDENRVWESDIRILKE 308
++ + N T R F S D+ ++ + +E ++E +++++E
Sbjct: 615 LDAVQRVDSAINSTRRHLFSQKPHTSSDLLAQFHYPRDPLIVEMARAGEIFEHTLQLIRE 674
Query: 309 HLGEQEVSISL 319
+ +Q +++ L
Sbjct: 675 RV-KQGLTVDL 684
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.319 0.136 0.413
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 27,069,223
Number of Sequences: 37866
Number of extensions: 1245930
Number of successful extensions: 4608
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 85
Number of HSP's successfully gapped in prelim test: 149
Number of HSP's that attempted gapping in prelim test: 3246
Number of HSP's gapped (non-prelim): 1184
length of query: 696
length of database: 18,247,518
effective HSP length: 109
effective length of query: 587
effective length of database: 14,120,124
effective search space: 8288512788
effective search space used: 8288512788
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.