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Search of human proteins with 76150623
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|76150623 nucleolar protein 1, 120kDa [Homo sapiens]
(808 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|76150625 nucleolar protein 1, 120kDa [Homo sapiens] 1610 0.0
gi|76150623 nucleolar protein 1, 120kDa [Homo sapiens] 1610 0.0
gi|23199998 NOL1/NOP2/Sun domain family, member 5 isoform 1 [Hom... 109 9e-24
gi|8922322 NOL1/NOP2/Sun domain family, member 5 isoform 2 [Homo... 107 4e-23
gi|32698918 NOL1/NOP2/Sun domain family, member 6 [Homo sapiens] 103 8e-22
gi|39995082 NOL1/NOP2/Sun domain family, member 2 [Homo sapiens] 89 2e-17
gi|40316918 NOL1/NOP2/Sun domain family 4 protein [Homo sapiens] 81 4e-15
gi|87298836 NOL1/NOP2/Sun domain family, member 5C isoform 1 [Ho... 77 5e-14
gi|23200000 NOL1/NOP2/Sun domain family, member 5C isoform 1 [Ho... 77 5e-14
gi|11545785 NOL1/NOP2/Sun domain family, member 3 [Homo sapiens] 76 1e-13
gi|23200002 NOL1/NOP2/Sun domain family, member 5C isoform 2 [Ho... 70 1e-11
gi|55956788 nucleolin [Homo sapiens] 55 3e-07
gi|4504487 histidine rich calcium binding protein precursor [Hom... 54 8e-07
gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Hom... 50 1e-05
gi|156104891 general transcription factor IIF, polypeptide 1, 74... 49 2e-05
gi|148596949 nucleolar and coiled-body phosphoprotein 1 [Homo sa... 48 4e-05
gi|20336260 retinoblastoma protein-binding zinc finger protein i... 48 4e-05
gi|20336258 retinoblastoma protein-binding zinc finger protein i... 48 4e-05
gi|148763345 cell division cycle 2-like 2 isoform 4 [Homo sapiens] 47 7e-05
gi|148763347 cell division cycle 2-like 2 isoform 1 [Homo sapiens] 47 7e-05
gi|69354671 ATP-binding cassette, sub-family F, member 1 isoform... 46 2e-04
gi|155030232 proline, glutamic acid and leucine rich protein 1 [... 46 2e-04
gi|117414137 retinitis pigmentosa 1-like 1 [Homo sapiens] 45 3e-04
gi|4503351 DNA (cytosine-5-)-methyltransferase 1 isoform b [Homo... 45 4e-04
gi|16332372 cell division cycle 2-like 1 (PITSLRE proteins) isof... 45 4e-04
gi|16332370 cell division cycle 2-like 1 (PITSLRE proteins) isof... 45 4e-04
gi|16332364 cell division cycle 2-like 1 (PITSLRE proteins) isof... 45 4e-04
gi|16332362 cell division cycle 2-like 1 (PITSLRE proteins) isof... 45 4e-04
gi|16332358 cell division cycle 2-like 1 (PITSLRE proteins) isof... 45 4e-04
gi|150170670 piccolo isoform 2 [Homo sapiens] 44 5e-04
>gi|76150625 nucleolar protein 1, 120kDa [Homo sapiens]
Length = 808
Score = 1610 bits (4169), Expect = 0.0
Identities = 808/808 (100%), Positives = 808/808 (100%)
Query: 1 MGRKLDPTKEKRGPGRKARKQKGAETELVRFLPAVSDENSKRLSSRARKRAAKRRLGSVE 60
MGRKLDPTKEKRGPGRKARKQKGAETELVRFLPAVSDENSKRLSSRARKRAAKRRLGSVE
Sbjct: 1 MGRKLDPTKEKRGPGRKARKQKGAETELVRFLPAVSDENSKRLSSRARKRAAKRRLGSVE 60
Query: 61 APKTNKSPEAKPLPGKLPKGAVQTAGKKGPQSLFNAPRGKKRPAPGSDEEEEEEDSEEDG 120
APKTNKSPEAKPLPGKLPKGAVQTAGKKGPQSLFNAPRGKKRPAPGSDEEEEEEDSEEDG
Sbjct: 61 APKTNKSPEAKPLPGKLPKGAVQTAGKKGPQSLFNAPRGKKRPAPGSDEEEEEEDSEEDG 120
Query: 121 MVNHGDLWGSEDDADTVDDYGADSNSEDEEEGEALLPIERAARKQKAREAAAGIQWSEEE 180
MVNHGDLWGSEDDADTVDDYGADSNSEDEEEGEALLPIERAARKQKAREAAAGIQWSEEE
Sbjct: 121 MVNHGDLWGSEDDADTVDDYGADSNSEDEEEGEALLPIERAARKQKAREAAAGIQWSEEE 180
Query: 181 TEDEEEEKEVTPESGPPKVEEADGGLQINVDEEPFVLPPAGEMEQDAQAPDLQRVHKRIQ 240
TEDEEEEKEVTPESGPPKVEEADGGLQINVDEEPFVLPPAGEMEQDAQAPDLQRVHKRIQ
Sbjct: 181 TEDEEEEKEVTPESGPPKVEEADGGLQINVDEEPFVLPPAGEMEQDAQAPDLQRVHKRIQ 240
Query: 241 DIVGILRDFGAQREEGRSRSEYLNRLKKDLAIYYSYGDFLLGKLMDLFPLSELVEFLEAN 300
DIVGILRDFGAQREEGRSRSEYLNRLKKDLAIYYSYGDFLLGKLMDLFPLSELVEFLEAN
Sbjct: 241 DIVGILRDFGAQREEGRSRSEYLNRLKKDLAIYYSYGDFLLGKLMDLFPLSELVEFLEAN 300
Query: 301 EVPRPVTLRTNTLKTRRRDLAQALINRGVNLDPLGKWSKTGLVVYDSSVPIGATPEYLAG 360
EVPRPVTLRTNTLKTRRRDLAQALINRGVNLDPLGKWSKTGLVVYDSSVPIGATPEYLAG
Sbjct: 301 EVPRPVTLRTNTLKTRRRDLAQALINRGVNLDPLGKWSKTGLVVYDSSVPIGATPEYLAG 360
Query: 361 HYMLQGASSMLPVMALAPQEHERILDMCCAPGGKTSYMAQLMKNTGVILANDANAERLKS 420
HYMLQGASSMLPVMALAPQEHERILDMCCAPGGKTSYMAQLMKNTGVILANDANAERLKS
Sbjct: 361 HYMLQGASSMLPVMALAPQEHERILDMCCAPGGKTSYMAQLMKNTGVILANDANAERLKS 420
Query: 421 VVGNLHRLGVTNTIISHYDGRQFPKVVGGFDRVLLDAPCSGTGVISKDPAVKTNKDEKDI 480
VVGNLHRLGVTNTIISHYDGRQFPKVVGGFDRVLLDAPCSGTGVISKDPAVKTNKDEKDI
Sbjct: 421 VVGNLHRLGVTNTIISHYDGRQFPKVVGGFDRVLLDAPCSGTGVISKDPAVKTNKDEKDI 480
Query: 481 LRCAHLQKELLLSAIDSVNATSKTGGYLVYCTCSITVEENEWVVDYALKKRNVRLVPTGL 540
LRCAHLQKELLLSAIDSVNATSKTGGYLVYCTCSITVEENEWVVDYALKKRNVRLVPTGL
Sbjct: 481 LRCAHLQKELLLSAIDSVNATSKTGGYLVYCTCSITVEENEWVVDYALKKRNVRLVPTGL 540
Query: 541 DFGQEGFTRFRERRFHPSLRSTRRFYPHTHNMDGFFIAKFKKFSNSIPQSQTGNSETATP 600
DFGQEGFTRFRERRFHPSLRSTRRFYPHTHNMDGFFIAKFKKFSNSIPQSQTGNSETATP
Sbjct: 541 DFGQEGFTRFRERRFHPSLRSTRRFYPHTHNMDGFFIAKFKKFSNSIPQSQTGNSETATP 600
Query: 601 TNVDLPQVIPKSENSSQPAKKAKGAAKTKQQLQKQQHPKKASFQKLNGISKGADSELSTV 660
TNVDLPQVIPKSENSSQPAKKAKGAAKTKQQLQKQQHPKKASFQKLNGISKGADSELSTV
Sbjct: 601 TNVDLPQVIPKSENSSQPAKKAKGAAKTKQQLQKQQHPKKASFQKLNGISKGADSELSTV 660
Query: 661 PSVTKTQASSSFQDSSQPAGKAEGIREPKVTGKLKQRSPKLQSSKKVAFLRQNAPPKGTD 720
PSVTKTQASSSFQDSSQPAGKAEGIREPKVTGKLKQRSPKLQSSKKVAFLRQNAPPKGTD
Sbjct: 661 PSVTKTQASSSFQDSSQPAGKAEGIREPKVTGKLKQRSPKLQSSKKVAFLRQNAPPKGTD 720
Query: 721 TQTPAVLSPSKTQATLKPKDHHQPLGRAKGVEKQQLPEQPFEKAAFQKQNDTPKGPQPPT 780
TQTPAVLSPSKTQATLKPKDHHQPLGRAKGVEKQQLPEQPFEKAAFQKQNDTPKGPQPPT
Sbjct: 721 TQTPAVLSPSKTQATLKPKDHHQPLGRAKGVEKQQLPEQPFEKAAFQKQNDTPKGPQPPT 780
Query: 781 VSPIRSSRPPPAKRKKSQSRGNSQLLLS 808
VSPIRSSRPPPAKRKKSQSRGNSQLLLS
Sbjct: 781 VSPIRSSRPPPAKRKKSQSRGNSQLLLS 808
>gi|76150623 nucleolar protein 1, 120kDa [Homo sapiens]
Length = 808
Score = 1610 bits (4169), Expect = 0.0
Identities = 808/808 (100%), Positives = 808/808 (100%)
Query: 1 MGRKLDPTKEKRGPGRKARKQKGAETELVRFLPAVSDENSKRLSSRARKRAAKRRLGSVE 60
MGRKLDPTKEKRGPGRKARKQKGAETELVRFLPAVSDENSKRLSSRARKRAAKRRLGSVE
Sbjct: 1 MGRKLDPTKEKRGPGRKARKQKGAETELVRFLPAVSDENSKRLSSRARKRAAKRRLGSVE 60
Query: 61 APKTNKSPEAKPLPGKLPKGAVQTAGKKGPQSLFNAPRGKKRPAPGSDEEEEEEDSEEDG 120
APKTNKSPEAKPLPGKLPKGAVQTAGKKGPQSLFNAPRGKKRPAPGSDEEEEEEDSEEDG
Sbjct: 61 APKTNKSPEAKPLPGKLPKGAVQTAGKKGPQSLFNAPRGKKRPAPGSDEEEEEEDSEEDG 120
Query: 121 MVNHGDLWGSEDDADTVDDYGADSNSEDEEEGEALLPIERAARKQKAREAAAGIQWSEEE 180
MVNHGDLWGSEDDADTVDDYGADSNSEDEEEGEALLPIERAARKQKAREAAAGIQWSEEE
Sbjct: 121 MVNHGDLWGSEDDADTVDDYGADSNSEDEEEGEALLPIERAARKQKAREAAAGIQWSEEE 180
Query: 181 TEDEEEEKEVTPESGPPKVEEADGGLQINVDEEPFVLPPAGEMEQDAQAPDLQRVHKRIQ 240
TEDEEEEKEVTPESGPPKVEEADGGLQINVDEEPFVLPPAGEMEQDAQAPDLQRVHKRIQ
Sbjct: 181 TEDEEEEKEVTPESGPPKVEEADGGLQINVDEEPFVLPPAGEMEQDAQAPDLQRVHKRIQ 240
Query: 241 DIVGILRDFGAQREEGRSRSEYLNRLKKDLAIYYSYGDFLLGKLMDLFPLSELVEFLEAN 300
DIVGILRDFGAQREEGRSRSEYLNRLKKDLAIYYSYGDFLLGKLMDLFPLSELVEFLEAN
Sbjct: 241 DIVGILRDFGAQREEGRSRSEYLNRLKKDLAIYYSYGDFLLGKLMDLFPLSELVEFLEAN 300
Query: 301 EVPRPVTLRTNTLKTRRRDLAQALINRGVNLDPLGKWSKTGLVVYDSSVPIGATPEYLAG 360
EVPRPVTLRTNTLKTRRRDLAQALINRGVNLDPLGKWSKTGLVVYDSSVPIGATPEYLAG
Sbjct: 301 EVPRPVTLRTNTLKTRRRDLAQALINRGVNLDPLGKWSKTGLVVYDSSVPIGATPEYLAG 360
Query: 361 HYMLQGASSMLPVMALAPQEHERILDMCCAPGGKTSYMAQLMKNTGVILANDANAERLKS 420
HYMLQGASSMLPVMALAPQEHERILDMCCAPGGKTSYMAQLMKNTGVILANDANAERLKS
Sbjct: 361 HYMLQGASSMLPVMALAPQEHERILDMCCAPGGKTSYMAQLMKNTGVILANDANAERLKS 420
Query: 421 VVGNLHRLGVTNTIISHYDGRQFPKVVGGFDRVLLDAPCSGTGVISKDPAVKTNKDEKDI 480
VVGNLHRLGVTNTIISHYDGRQFPKVVGGFDRVLLDAPCSGTGVISKDPAVKTNKDEKDI
Sbjct: 421 VVGNLHRLGVTNTIISHYDGRQFPKVVGGFDRVLLDAPCSGTGVISKDPAVKTNKDEKDI 480
Query: 481 LRCAHLQKELLLSAIDSVNATSKTGGYLVYCTCSITVEENEWVVDYALKKRNVRLVPTGL 540
LRCAHLQKELLLSAIDSVNATSKTGGYLVYCTCSITVEENEWVVDYALKKRNVRLVPTGL
Sbjct: 481 LRCAHLQKELLLSAIDSVNATSKTGGYLVYCTCSITVEENEWVVDYALKKRNVRLVPTGL 540
Query: 541 DFGQEGFTRFRERRFHPSLRSTRRFYPHTHNMDGFFIAKFKKFSNSIPQSQTGNSETATP 600
DFGQEGFTRFRERRFHPSLRSTRRFYPHTHNMDGFFIAKFKKFSNSIPQSQTGNSETATP
Sbjct: 541 DFGQEGFTRFRERRFHPSLRSTRRFYPHTHNMDGFFIAKFKKFSNSIPQSQTGNSETATP 600
Query: 601 TNVDLPQVIPKSENSSQPAKKAKGAAKTKQQLQKQQHPKKASFQKLNGISKGADSELSTV 660
TNVDLPQVIPKSENSSQPAKKAKGAAKTKQQLQKQQHPKKASFQKLNGISKGADSELSTV
Sbjct: 601 TNVDLPQVIPKSENSSQPAKKAKGAAKTKQQLQKQQHPKKASFQKLNGISKGADSELSTV 660
Query: 661 PSVTKTQASSSFQDSSQPAGKAEGIREPKVTGKLKQRSPKLQSSKKVAFLRQNAPPKGTD 720
PSVTKTQASSSFQDSSQPAGKAEGIREPKVTGKLKQRSPKLQSSKKVAFLRQNAPPKGTD
Sbjct: 661 PSVTKTQASSSFQDSSQPAGKAEGIREPKVTGKLKQRSPKLQSSKKVAFLRQNAPPKGTD 720
Query: 721 TQTPAVLSPSKTQATLKPKDHHQPLGRAKGVEKQQLPEQPFEKAAFQKQNDTPKGPQPPT 780
TQTPAVLSPSKTQATLKPKDHHQPLGRAKGVEKQQLPEQPFEKAAFQKQNDTPKGPQPPT
Sbjct: 721 TQTPAVLSPSKTQATLKPKDHHQPLGRAKGVEKQQLPEQPFEKAAFQKQNDTPKGPQPPT 780
Query: 781 VSPIRSSRPPPAKRKKSQSRGNSQLLLS 808
VSPIRSSRPPPAKRKKSQSRGNSQLLLS
Sbjct: 781 VSPIRSSRPPPAKRKKSQSRGNSQLLLS 808
>gi|23199998 NOL1/NOP2/Sun domain family, member 5 isoform 1 [Homo
sapiens]
Length = 466
Score = 109 bits (273), Expect = 9e-24
Identities = 109/352 (30%), Positives = 155/352 (44%), Gaps = 57/352 (16%)
Query: 299 ANEVPRPVTLRTNTLKTRRRDLAQALINRGVN--------------------LDPLGKWS 338
A+++PR V R NTLKT D+ +G + LDPL
Sbjct: 131 ASQLPRFV--RVNTLKTCSDDVVDYFKRQGFSYQGRASSLDDLRALKGKHFLLDPL---- 184
Query: 339 KTGLVVYDSSVPIGATPEYLAGHYMLQGASSMLPVMALAPQEHERILDMCCAPGGKTSYM 398
L+V+ + + P Y AGH +LQ +S LP M L P ++D C APG KTS++
Sbjct: 185 MPELLVFPAQTDLHEHPLYRAGHLILQDRASCLPAMLLDPPPGSHVIDACAAPGNKTSHL 244
Query: 399 AQLMKNTGVILANDANAERLKSVVGNLHRLGVTNTIISHYDGRQFPKVVGGFDR------ 452
A L+KN G I A D +A+RL S+ L R GV+ ++ D F V R
Sbjct: 245 AALLKNQGKIFAFDLDAKRLASMATLLARAGVSCCELAEED---FLAVSPSDPRYHEVHY 301
Query: 453 VLLDAPCSGTGVISK---DPAVKTNKDEKDILRCAHLQKELLLSAIDSVNATSKTGGYLV 509
+LLD CSG+G+ S+ +P T + + A Q+ L A+ T + LV
Sbjct: 302 ILLDPSCSGSGMPSRQLEEPGAGTPSPVR-LHALAGFQQRALCHAL-----TFPSLQRLV 355
Query: 510 YCTCSITVEENEWVVDYALKKR--NVRLVPTGLDFGQEGFTRFRERRFHPSLRSTRRFYP 567
Y TCS+ EENE VV AL++ RL P + G + F P R P
Sbjct: 356 YSTCSLCQEENEDVVRDALQQNPGAFRLAPALPAWPHRGLSTF------PGAEHCLRASP 409
Query: 568 HTHNMDGFFIAKFKKFSNSIPQSQTGNSETATPTNVDLPQVIPKSENSSQPA 619
T GFF+A ++ +P S ++ + P P PK + Q A
Sbjct: 410 ETTLSSGFFVAVIERV--EVP-SSASQAKASAPERT--PSPAPKRKKRQQRA 456
>gi|8922322 NOL1/NOP2/Sun domain family, member 5 isoform 2 [Homo
sapiens]
Length = 429
Score = 107 bits (267), Expect = 4e-23
Identities = 101/315 (32%), Positives = 142/315 (45%), Gaps = 52/315 (16%)
Query: 299 ANEVPRPVTLRTNTLKTRRRDLAQALINRGVN--------------------LDPLGKWS 338
A+++PR V R NTLKT D+ +G + LDPL
Sbjct: 131 ASQLPRFV--RVNTLKTCSDDVVDYFKRQGFSYQGRASSLDDLRALKGKHFLLDPL---- 184
Query: 339 KTGLVVYDSSVPIGATPEYLAGHYMLQGASSMLPVMALAPQEHERILDMCCAPGGKTSYM 398
L+V+ + + P Y AGH +LQ +S LP M L P ++D C APG KTS++
Sbjct: 185 MPELLVFPAQTDLHEHPLYRAGHLILQDRASCLPAMLLDPPPGSHVIDACAAPGNKTSHL 244
Query: 399 AQLMKNTGVILANDANAERLKSVVGNLHRLGVTNTIISHYDGRQFPKVVGGFDR------ 452
A L+KN G I A D +A+RL S+ L R GV+ ++ D F V R
Sbjct: 245 AALLKNQGKIFAFDLDAKRLASMATLLARAGVSCCELAEED---FLAVSPSDPRYHEVHY 301
Query: 453 VLLDAPCSGTGVISK---DPAVKTNKDEKDILRCAHLQKELLLSAIDSVNATSKTGGYLV 509
+LLD CSG+G+ S+ +P T + + A Q+ L A+ T + LV
Sbjct: 302 ILLDPSCSGSGMPSRQLEEPGAGTPSPVR-LHALAGFQQRALCHAL-----TFPSLQRLV 355
Query: 510 YCTCSITVEENEWVVDYALKKR--NVRLVPTGLDFGQEGFTRFRERRFHPSLRSTRRFYP 567
Y TCS+ EENE VV AL++ RL P + G + F P R P
Sbjct: 356 YSTCSLCQEENEDVVRDALQQNPGAFRLAPALPAWPHRGLSTF------PGAEHCLRASP 409
Query: 568 HTHNMDGFFIAKFKK 582
T GFF+A ++
Sbjct: 410 ETTLSSGFFVAVIER 424
>gi|32698918 NOL1/NOP2/Sun domain family, member 6 [Homo sapiens]
Length = 469
Score = 103 bits (256), Expect = 8e-22
Identities = 90/272 (33%), Positives = 128/272 (47%), Gaps = 46/272 (16%)
Query: 350 PIGATPEY---LAGHYMLQGASSMLPVMALAPQEHERILDMCCAPGGKTSYMAQLMKNTG 406
P+ +P + L + LQ S L L PQ E+ILD+C APGGKT+++A LM + G
Sbjct: 201 PVYLSPSFDSVLPRYLFLQNLPSALVSHVLNPQPGEKILDLCAAPGGKTTHIAALMHDQG 260
Query: 407 VILANDANAERLKSVVGNLHRLGVTNTIISHYDGRQF-------------PKVVGGFDRV 453
++A D +++ + N LG+ + +DG + P + FDR+
Sbjct: 261 EVIALDKIFNKVEKIKQNALLLGLNSIRAFCFDGTKAVKLDMVEDTEGEPPFLPESFDRI 320
Query: 454 LLDAPCSGTGVISKDPAVKTNKDEKDILRCAHLQKELLLSAIDSVNATSKTGGYLVYCTC 513
LLDAPCSG G + P + K++ LQ++L +A+ + K G LVY TC
Sbjct: 321 LLDAPCSGMG---QRPNMACTWSVKEVASYQPLQRKLFTAAVQLL----KPEGVLVYSTC 373
Query: 514 SITVEENEWVVDYALKK-RNVRLVPTGLDFGQEGFTRF--------RERRFHP------- 557
+IT+ ENE V +AL K ++L P G EG + +RF P
Sbjct: 374 TITLAENEEQVAWALTKFPCLQLQPQEPQIGGEGMRGAGLSCEQLKQLQRFDPSAVPLPD 433
Query: 558 ----SLRSTRR-FYPHTHNMD--GFFIAKFKK 582
SLR RR N D GFFIAKF K
Sbjct: 434 TDMDSLREARREDMLRLANKDSIGFFIAKFVK 465
>gi|39995082 NOL1/NOP2/Sun domain family, member 2 [Homo sapiens]
Length = 767
Score = 88.6 bits (218), Expect = 2e-17
Identities = 108/463 (23%), Positives = 171/463 (36%), Gaps = 107/463 (23%)
Query: 250 GAQREEGRSRSEYLNRLKKDLAIYYSYGDFLLGKLMDLFPLSELVEFLEANEVPRPVTLR 309
G +R E Y +K++ + Y + + + P E +F++A P P TLR
Sbjct: 26 GGKRGEAGWEGGYPEIVKENKLFEHYYQE------LKIVPEGEWGQFMDALREPLPATLR 79
Query: 310 TNTLKTRRRDLAQALINRGVNLDPLGKWSKTGLVVYDSSVPIGATPEYLAGHYML----- 364
K+ +++ L N+ L G V + P+ PE LA H L
Sbjct: 80 ITGYKSHAKEILHCLKNK--YFKELEDLEVDGQKV-EVPQPLSWYPEELAWHTNLSRKIL 136
Query: 365 ------------------------QGASSMLPVMALAPQEHERILDMCCAPGGKTSYMAQ 400
Q A SM+P + L + H +ILDMC APG KT+ + +
Sbjct: 137 RKSPHLEKFHQFLVSETESGNISRQEAVSMIPPLLLNVRPHHKILDMCAAPGSKTTQLIE 196
Query: 401 LMK-------NTGVILANDANAERLKSVVGNLHRLGVTNTIISHYDGRQFPKV---VGG- 449
++ G ++AND + +R +V RL ++ ++D P++ V G
Sbjct: 197 MLHADMNVPFPEGFVIANDVDNKRCYLLVHQAKRLSSPCIMVVNHDASSIPRLQIDVDGR 256
Query: 450 -----FDRVLLDAPCSGTGVISKDPAVKTNKDEKDILRCAHLQKELLLSAIDSVNATSKT 504
+DR+L D PCSG G + K+ V + L+ LQ + + +
Sbjct: 257 KEILFYDRILCDVPCSGDGTMRKNIDVWKKWTTLNSLQLHGLQLRIATRGAEQL----AE 312
Query: 505 GGYLVYCTCSITVEENEWVVDYALKKRNVRLVPTGLDFGQEGF----------------- 547
GG +VY TCS+ E+E V+ L+K L + G
Sbjct: 313 GGRMVYSTCSLNPIEDEAVIASLLEKSEGALELADVSNELPGLKWMPGITQWKVMTKDGQ 372
Query: 548 -------------TRFRERRFHPS---------LRSTRRFYPHTHNMDGFFIAKFKK--- 582
T+ R F P L R PH N GFF+A K
Sbjct: 373 WFTDWDAVPHSRHTQIRPTMFPPKDPEKLQAMHLERCLRILPHHQNTGGFFVAVLVKKSS 432
Query: 583 --FSNSIPQSQTGNSETATPTNVDLPQVIPKSENSSQPAKKAK 623
++ P+ Q ++ET T Q+ P +P +K
Sbjct: 433 MPWNKRQPKLQGKSAETREST-----QLSPADLTEGKPTDPSK 470
>gi|40316918 NOL1/NOP2/Sun domain family 4 protein [Homo sapiens]
Length = 384
Score = 80.9 bits (198), Expect = 4e-15
Identities = 61/182 (33%), Positives = 100/182 (54%), Gaps = 24/182 (13%)
Query: 362 YMLQGASSMLPVMALAPQEHERILDMCCAPGGKTSYMAQLMKNTGV---ILANDANAERL 418
Y L A+S+LPV+AL Q + +LD+C APGGKT + Q TG + AND + R+
Sbjct: 155 YYLMDAASLLPVLALGLQPGDIVLDLCAAPGGKTLALLQ----TGCCRNLAANDLSPSRI 210
Query: 419 KSVVGNLH-----RLGVTNTI-ISHYDGRQFPKVVGG-FDRVLLDAPCS----GTGVISK 467
+ LH + N + ++ +DGR++ ++ G +DRVL+D PC+
Sbjct: 211 ARLQKILHSYVPEEIRDGNQVRVTSWDGRKWGELEGDTYDRVLVDVPCTTDRHSLHEEEN 270
Query: 468 DPAVKTNKDEKDILRCAHLQKELLLSAIDSVNATSKTGGYLVYCTCSITVEENEWVVDYA 527
+ ++ K E+ IL LQ +LL + + +K GG++VY TCS++ +NE+VV A
Sbjct: 271 NIFKRSRKKERQILPV--LQVQLLAAGL----LATKPGGHVVYSTCSLSHLQNEYVVQGA 324
Query: 528 LK 529
++
Sbjct: 325 IE 326
>gi|87298836 NOL1/NOP2/Sun domain family, member 5C isoform 1 [Homo
sapiens]
Length = 315
Score = 77.4 bits (189), Expect = 5e-14
Identities = 85/295 (28%), Positives = 125/295 (42%), Gaps = 35/295 (11%)
Query: 342 LVVYDSSVPIGATPEYLAGHYMLQGASSMLPVMALAPQEHERILDMCCAPGGKTSYMAQL 401
L+V+ + + P Y AGH +LQ +S LP M L P++ KTS++A L
Sbjct: 4 LLVFPAQTDLHEHPLYRAGHLILQDRASCLPAMLLDPRQAPMSWMPVPPQAIKTSHLAAL 63
Query: 402 MKNTGVILANDANAERLKSVVGNLHRLGVTNTIISHYDGRQFPKVVGGFDR---VLLDAP 458
+KN G I A D +A RL S+ L GV+ ++ D + + VLLD
Sbjct: 64 LKNQGKIFAFDLDARRLASMATLLAWAGVSCCELAEEDFLAVSPLDPRYREVHYVLLDPS 123
Query: 459 CSGTGVISK---DPAVKTNKDEKDILRCAHLQKELLLSAIDSVNATSKTGGYLVYCTCSI 515
CSG+G+ S+ +P T + + A Q+ L A+ T + LVY CS+
Sbjct: 124 CSGSGMPSRQLEEPGAGTPSPVR-LHALAGFQQRALCHAL-----TFPSLQRLVYSMCSL 177
Query: 516 TVEENEWVVDYALKKR--NVRLVPTGLDFGQEGFTRFRERRFHPSLRSTRRFYPHTHNMD 573
EENE +V AL++ RL P G + F P R P T
Sbjct: 178 CQEENEDMVQDALQQNPGAFRLAPALPARPHRGLSTF------PGAEHCLRASPKTTLSG 231
Query: 574 GFFIAKFKKFSNSIPQSQTGNSETATPTNVDLPQVIPKSENSSQPAKKAKGAAKT 628
GFF+A ++ SQ ++ + P E + PA K K AK+
Sbjct: 232 GFFVAVIERVEMPTSASQ---AKASAP------------ERTPSPAPKRKKRAKS 271
>gi|23200000 NOL1/NOP2/Sun domain family, member 5C isoform 1 [Homo
sapiens]
Length = 315
Score = 77.4 bits (189), Expect = 5e-14
Identities = 85/295 (28%), Positives = 125/295 (42%), Gaps = 35/295 (11%)
Query: 342 LVVYDSSVPIGATPEYLAGHYMLQGASSMLPVMALAPQEHERILDMCCAPGGKTSYMAQL 401
L+V+ + + P Y AGH +LQ +S LP M L P++ KTS++A L
Sbjct: 4 LLVFPAQTDLHEHPLYRAGHLILQDRASCLPAMLLDPRQAPMSWMPVPPQAIKTSHLAAL 63
Query: 402 MKNTGVILANDANAERLKSVVGNLHRLGVTNTIISHYDGRQFPKVVGGFDR---VLLDAP 458
+KN G I A D +A RL S+ L GV+ ++ D + + VLLD
Sbjct: 64 LKNQGKIFAFDLDARRLASMATLLAWAGVSCCELAEEDFLAVSPLDPRYREVHYVLLDPS 123
Query: 459 CSGTGVISK---DPAVKTNKDEKDILRCAHLQKELLLSAIDSVNATSKTGGYLVYCTCSI 515
CSG+G+ S+ +P T + + A Q+ L A+ T + LVY CS+
Sbjct: 124 CSGSGMPSRQLEEPGAGTPSPVR-LHALAGFQQRALCHAL-----TFPSLQRLVYSMCSL 177
Query: 516 TVEENEWVVDYALKKR--NVRLVPTGLDFGQEGFTRFRERRFHPSLRSTRRFYPHTHNMD 573
EENE +V AL++ RL P G + F P R P T
Sbjct: 178 CQEENEDMVQDALQQNPGAFRLAPALPARPHRGLSTF------PGAEHCLRASPKTTLSG 231
Query: 574 GFFIAKFKKFSNSIPQSQTGNSETATPTNVDLPQVIPKSENSSQPAKKAKGAAKT 628
GFF+A ++ SQ ++ + P E + PA K K AK+
Sbjct: 232 GFFVAVIERVEMPTSASQ---AKASAP------------ERTPSPAPKRKKRAKS 271
>gi|11545785 NOL1/NOP2/Sun domain family, member 3 [Homo sapiens]
Length = 340
Score = 75.9 bits (185), Expect = 1e-13
Identities = 62/177 (35%), Positives = 97/177 (54%), Gaps = 19/177 (10%)
Query: 362 YMLQGASSMLPVMALAPQEHERILDMCCAPGGKTSYMAQLMKNTGVILANDANAERLKSV 421
Y L A+S+LPV+AL ++ E++LD+C APGGK+ + Q G + N+ ++ RL+ +
Sbjct: 113 YYLLNAASLLPVLALELRDGEKVLDLCAAPGGKSIALLQ-CACPGYLHCNEYDSLRLRWL 171
Query: 422 VGNLHRL---GVTNTI-ISHYDGRQF----PKVVGGFDRVLLDAPCSG--TGVISKDPAV 471
L + N I +S DGR+ P++ FD+VL+DAPCS + + S D +
Sbjct: 172 RQTLESFIPQPLINVIKVSELDGRKMGDAQPEM---FDKVLVDAPCSNDRSWLFSSD-SQ 227
Query: 472 KTNKDEKDILRCAHLQKELLLSAIDSVNATSKTGGYLVYCTCSITVEENEWVVDYAL 528
K + LQ ELL SAI ++ + GG LVY TC+++ EN+ V+ L
Sbjct: 228 KASCRISQRRNLPLLQIELLRSAIKAL----RPGGILVYSTCTLSKAENQDVISEIL 280
>gi|23200002 NOL1/NOP2/Sun domain family, member 5C isoform 2 [Homo
sapiens]
Length = 291
Score = 69.7 bits (169), Expect = 1e-11
Identities = 80/295 (27%), Positives = 115/295 (38%), Gaps = 59/295 (20%)
Query: 342 LVVYDSSVPIGATPEYLAGHYMLQGASSMLPVMALAPQEHERILDMCCAPGGKTSYMAQL 401
L+V+ + + P Y AGH +LQ +S LP M L P++ KTS++A L
Sbjct: 4 LLVFPAQTDLHEHPLYRAGHLILQDRASCLPAMLLDPRQAPMSWMPVPPQAIKTSHLAAL 63
Query: 402 MKNTGVILANDANAERLKSVVGNLHRLGVTNTIISHYDGRQFPKVVGGFDR---VLLDAP 458
+KN G I A D +A RL S+ L GV+ ++ D + + VLLD
Sbjct: 64 LKNQGKIFAFDLDARRLASMATLLAWAGVSCCELAEEDFLAVSPLDPRYREVHYVLLDPS 123
Query: 459 CSGTGVISK---DPAVKTNKDEKDILRCAHLQKELLLSAIDSVNATSKTGGYLVYCTCSI 515
CSG+G+ S+ +P T LVY CS+
Sbjct: 124 CSGSGMPSRQLEEPGAGTPSPR------------------------------LVYSMCSL 153
Query: 516 TVEENEWVVDYALKKR--NVRLVPTGLDFGQEGFTRFRERRFHPSLRSTRRFYPHTHNMD 573
EENE +V AL++ RL P G + F P R P T
Sbjct: 154 CQEENEDMVQDALQQNPGAFRLAPALPARPHRGLSTF------PGAEHCLRASPKTTLSG 207
Query: 574 GFFIAKFKKFSNSIPQSQTGNSETATPTNVDLPQVIPKSENSSQPAKKAKGAAKT 628
GFF+A ++ SQ ++ + P E + PA K K AK+
Sbjct: 208 GFFVAVIERVEMPTSASQ---AKASAP------------ERTPSPAPKRKKRAKS 247
>gi|55956788 nucleolin [Homo sapiens]
Length = 710
Score = 55.1 bits (131), Expect = 3e-07
Identities = 65/253 (25%), Positives = 97/253 (38%), Gaps = 38/253 (15%)
Query: 14 PGRKARKQKGAETELVRFLPAVSDENSKRLSSRARKRAAK--RRLGSVEAPKTNKSPEAK 71
P +K +K + V VS +++ A+K A ++ + A KT +A
Sbjct: 49 PQKKGKKAAATSAKKV----VVSPTKKVAVATPAKKAAVTPGKKAAATPAKKTVTPAKAV 104
Query: 72 PLPGKLP----KGAVQTAGKKGPQSLFNAPRGKKRPAPGSDEEEEEEDSEEDGMVNHGD- 126
PGK K V T GKKG + K +EEE++DSEED + +
Sbjct: 105 TTPGKKGATPGKALVATPGKKGAAIPAKGAKNGKNAKKEDSDEEEDDDSEEDEEDDEDED 164
Query: 127 ------------------LWGSEDDADTVDDYGADSNSEDEEEGEALLPIERAARKQKAR 168
EDD D DD D + ED+ E EA+ A+ +KA
Sbjct: 165 EDEDEIEPAAMKAAAAAPASEDEDDEDDEDDEDDDDDEEDDSEEEAMETTP--AKGKKAA 222
Query: 169 EAAAGIQWSEEETEDEEE----EKEVTPESGPPKVEEADGGLQINVDEEPFVLPPA---G 221
+ + E EDEEE E + E +E D + +EEP P
Sbjct: 223 KVVPVKAKNVAEDEDEEEDDEDEDDDDDEDDEDDDDEDDEEEEEEEEEEPVKEAPGKRKK 282
Query: 222 EMEQDAQAPDLQR 234
EM + AP+ ++
Sbjct: 283 EMAKQKAAPEAKK 295
Score = 46.2 bits (108), Expect = 1e-04
Identities = 42/153 (27%), Positives = 64/153 (41%), Gaps = 38/153 (24%)
Query: 81 AVQTAGKKGPQSLFNAPRGKKRPAPGSDEEEEEEDSEEDGMVNHGDLWGSEDDADTVDDY 140
A++T KG ++ P K A DEEE++ED ++D DD D DD
Sbjct: 210 AMETTPAKGKKAAKVVPVKAKNVAEDEDEEEDDEDEDDD------------DDEDDEDDD 257
Query: 141 GADSNSEDEEEGEALLPIERAARKQKAREAAAGIQWSEEETEDEEEEKEVTPESGPPKVE 200
D E+EEE E P++ A K+K E +++ PE+ KVE
Sbjct: 258 DEDDEEEEEEEEEE--PVKEAPGKRK----------------KEMAKQKAAPEAKKQKVE 299
Query: 201 EADGGLQINVDEEPFVLPPAGEMEQDAQAPDLQ 233
+ N+ FV G + + AP+L+
Sbjct: 300 GTEPTTAFNL----FV----GNLNFNKSAPELK 324
>gi|4504487 histidine rich calcium binding protein precursor [Homo
sapiens]
Length = 699
Score = 53.5 bits (127), Expect = 8e-07
Identities = 30/97 (30%), Positives = 48/97 (49%), Gaps = 1/97 (1%)
Query: 100 KKRPAPGSDEEEEEEDSEEDGMVNHGDLWGSEDDADTVDDYGADSNSEDEEEGEALLPIE 159
+K PGS EE++E + + +HG ED+ D + +G N E+EEE + E
Sbjct: 487 EKEEDPGSHEEDDESSEQGEKGTHHGSR-DQEDEEDEEEGHGLSLNQEEEEEEDKEEEEE 545
Query: 160 RAARKQKAREAAAGIQWSEEETEDEEEEKEVTPESGP 196
+++ A G S + +E+EEEE+E E P
Sbjct: 546 EEDEERREERAEVGAPLSPDHSEEEEEEEEGLEEDEP 582
Score = 38.9 bits (89), Expect = 0.019
Identities = 30/104 (28%), Positives = 42/104 (40%), Gaps = 19/104 (18%)
Query: 108 DEEEEEEDSEEDGMVNHGDLWGSEDDADTVDDYGADSNSEDEEEGEALLPIERAARKQKA 167
D EEE+E E+ G D + + T + EDEEEG L
Sbjct: 481 DSEEEKEKEEDPGSHEEDDESSEQGEKGTHHGSRDQEDEEDEEEGHGL------------ 528
Query: 168 REAAAGIQWSEEETEDEEEEKEVTPESGPPKVEEADGGLQINVD 211
+ EEE ED+EEE+E E + E A+ G ++ D
Sbjct: 529 -----SLNQEEEEEEDKEEEEE--EEDEERREERAEVGAPLSPD 565
Score = 32.7 bits (73), Expect = 1.4
Identities = 32/135 (23%), Positives = 52/135 (38%), Gaps = 39/135 (28%)
Query: 98 RGKKRPAPGSDEEEEEEDSEEDGMVNHGDL------WGSEDDADTVDDY----------- 140
RG +EEEEEE+ EE+ +G GSE+D D D +
Sbjct: 183 RGHDGEDDEGEEEEEEEEEEEEASTEYGHQAHRHRGHGSEEDEDVSDGHHHHGPSHRHQG 242
Query: 141 ----GADSNSEDEEEGEALLPIERAARKQKAREAAAGIQWSEE----------------E 180
D + +D+++ + + IE R Q R GI+ E+
Sbjct: 243 HEEDDDDDDDDDDDDDDDDVSIE--YRHQAHRHQGHGIEEDEDVSDGHHHRDPSHRHRSH 300
Query: 181 TEDEEEEKEVTPESG 195
ED+ ++ +V+ E G
Sbjct: 301 EEDDNDDDDVSTEYG 315
Score = 30.0 bits (66), Expect = 9.0
Identities = 25/80 (31%), Positives = 33/80 (41%), Gaps = 13/80 (16%)
Query: 108 DEEEEEEDSEEDGMVNHGDLWGSEDDADTVDDYGADSNSEDEEEGEALLPIER----AAR 163
D+EEEEE+ +E+ E+ A+ D + E+EEE E L E
Sbjct: 539 DKEEEEEEEDEE---------RREERAEVGAPLSPDHSEEEEEEEEGLEEDEPRFTIIPN 589
Query: 164 KQKAREAAAGIQWSEEETED 183
RE A G EE ED
Sbjct: 590 PLDRREEAGGASSEEESGED 609
>gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Homo
sapiens]
Length = 1152
Score = 49.7 bits (117), Expect = 1e-05
Identities = 40/145 (27%), Positives = 64/145 (44%), Gaps = 22/145 (15%)
Query: 79 KGAVQTAGKKGPQSLFNAPRGKKRPAPGSDEEEEEE--------DSEEDGMVNHGDLWGS 130
+G ++ G+ G + L KKR +++E E+ + EE G HG+ G
Sbjct: 683 RGEMERPGE-GEKELAEKEEWKKRDGEEQEQKEREQGHQKERNQEMEEGGEEEHGE--GE 739
Query: 131 EDDADTVDDYGADSNSEDEEEGEAL-----------LPIERAARKQKAREAAAGIQWSEE 179
E++ D ++ + ++E EGE + ERA +++K E + EE
Sbjct: 740 EEEGDREEEEEKEGEGKEEGEGEEVEGEREKEEGERKKEERAGKEEKGEEEGDQGEGEEE 799
Query: 180 ETEDEEEEKEVTPESGPPKVEEADG 204
ETE EEKE E +VEE G
Sbjct: 800 ETEGRGEEKEEGGEVEGGEVEEGKG 824
Score = 44.7 bits (104), Expect = 4e-04
Identities = 47/204 (23%), Positives = 81/204 (39%), Gaps = 12/204 (5%)
Query: 2 GRKLDPTKEKRGPGRKARKQKGAETE-LVRFLPAVSDENSKRLSSRARKRAAKRRLGSVE 60
G +++ +EK RK ++ G E + +E ++ + G VE
Sbjct: 761 GEEVEGEREKEEGERKKEERAGKEEKGEEEGDQGEGEEEETEGRGEEKEEGGEVEGGEVE 820
Query: 61 APKTNKSPEAKPLPGKLPKGAVQTAGKKGPQSLFNAPRGKKRPAPGSDEEEEEEDSEEDG 120
K + E + G+ +G + +G + +G++ G EEE EE E +G
Sbjct: 821 EGKGEREEEEEEGEGEEEEGEGEEEEGEGEEEEGEG-KGEEEGEEGEGEEEGEE-GEGEG 878
Query: 121 MVNHGDLWGSEDDADTVDDYGADSNSEDEEEGEALLPIERAARKQKAREAAAGIQWSEEE 180
G+ G E+ ++ + E+E EGE +++ E + E E
Sbjct: 879 EEEEGEGEGEEEGEGEGEEEEGEGEGEEEGEGEG---------EEEEGEGKGEEEGEEGE 929
Query: 181 TEDEEEEKEVTPESGPPKVEEADG 204
E EEEE E E G + EE +G
Sbjct: 930 GEGEEEEGEGEGEDGEGEGEEEEG 953
Score = 42.0 bits (97), Expect = 0.002
Identities = 34/108 (31%), Positives = 50/108 (46%), Gaps = 8/108 (7%)
Query: 99 GKKRPAPGSDEEEE-EEDSEEDGM-VNHGDLWGSEDDADTVDDYGADSNSEDEEEGEALL 156
G++ G EEEE EE+ EE+G G+ G E++ V+ G E E EGE
Sbjct: 981 GEEEEGEGEGEEEEGEEEGEEEGEGEEEGEGEGEEEEEGEVE--GEVEGEEGEGEGEE-- 1036
Query: 157 PIERAARKQKAREAAAGIQWSEEETEDEEEEKEVTPESGPPKVEEADG 204
E + + RE + + E+EEEE+ E+G + E DG
Sbjct: 1037 --EEGEEEGEEREKEGEGEENRRNREEEEEEEGKYQETGEEENERQDG 1082
Score = 39.3 bits (90), Expect = 0.015
Identities = 43/182 (23%), Positives = 70/182 (38%), Gaps = 18/182 (9%)
Query: 99 GKKRPAPGSDEEEEEEDSEEDGMVNHGDLWGSEDDADTVDDYGADSNSE-----DEEEGE 153
G++ +EEE E EE+G G+ E + + D G E +EEEGE
Sbjct: 904 GEEEGEGEGEEEEGEGKGEEEGEEGEGEGEEEEGEGEGEDGEGEGEEEEGEWEGEEEEGE 963
Query: 154 ALLPIERAARKQKA-----REAAAGIQWSEEETEDEEEEKEVTPESGPPKVEEADGGLQI 208
E ++ E G EE E+ EEE E E EE +G ++
Sbjct: 964 GEGEEEGEGEGEEGEGEGEEEEGEGEGEEEEGEEEGEEEGEGEEEGEGEGEEEEEGEVEG 1023
Query: 209 NVD--------EEPFVLPPAGEMEQDAQAPDLQRVHKRIQDIVGILRDFGAQREEGRSRS 260
V+ EE E E++ + + +R + ++ G ++ G + E +
Sbjct: 1024 EVEGEEGEGEGEEEEGEEEGEEREKEGEGEENRRNREEEEEEEGKYQETGEEENERQDGE 1083
Query: 261 EY 262
EY
Sbjct: 1084 EY 1085
Score = 35.8 bits (81), Expect = 0.16
Identities = 41/162 (25%), Positives = 68/162 (41%), Gaps = 19/162 (11%)
Query: 99 GKKRPAPGSDEEEEEEDSEEDGM---VNHGDLWGSEDDADTVDDYGADSNSEDE------ 149
G+ G +EE E E EE+G G+ G E + + ++ G E+E
Sbjct: 941 GEDGEGEGEEEEGEWEGEEEEGEGEGEEEGEGEGEEGEGEGEEEEGEGEGEEEEGEEEGE 1000
Query: 150 EEGEALLPIERAARKQKAREAAAGIQWSEEETEDEEEEKEVTPESGPPKVEEADG----G 205
EEGE E +++ E ++ EE E E EE+E E G + +E +G
Sbjct: 1001 EEGEGEEEGEGEGEEEEEGEVEGEVEG--EEGEGEGEEEE-GEEEGEEREKEGEGEENRR 1057
Query: 206 LQINVDEEPFVLPPAGEMEQDAQAPDLQRVHKRIQDIVGILR 247
+ +EE GE E + Q + +K++ I G ++
Sbjct: 1058 NREEEEEEEGKYQETGEEENERQDGE---EYKKVSKIKGSVK 1096
Score = 31.2 bits (69), Expect = 4.0
Identities = 35/153 (22%), Positives = 60/153 (39%), Gaps = 6/153 (3%)
Query: 109 EEEEEEDSEEDGMVNHGDLWGSEDDADTVDDYGADSNSEDEEEGEALLPIERAARKQKAR 168
EE+E E +EE+ V+ G +E +D + D S + + GEA E
Sbjct: 602 EEQEVEANEENVKVHGGRKEKTEILSDDLTDKAEVSEGKAKSVGEAEDGPEGRGDGTCEE 661
Query: 169 EAAAGIQWSEEETEDEEEEKEVTPESGPPKVEEADGGLQINVDEEPFVLPPAGEMEQDAQ 228
++ W +EE E E++K G ++E G + ++E + E EQ +
Sbjct: 662 GSSGAEHWQDEEREKGEKDK------GRGEMERPGEGEKELAEKEEWKKRDGEEQEQKER 715
Query: 229 APDLQRVHKRIQDIVGILRDFGAQREEGRSRSE 261
Q+ + + G + EEG E
Sbjct: 716 EQGHQKERNQEMEEGGEEEHGEGEEEEGDREEE 748
Score = 30.4 bits (67), Expect = 6.9
Identities = 39/175 (22%), Positives = 67/175 (38%), Gaps = 23/175 (13%)
Query: 41 KRLSSRARKRAAKRRLGSVEAPKTNKSPEAKPLPGKLPKGAVQTAGKKGPQSLFNAPRGK 100
+ LS+R R+R +R S +T P+ G L A P S+F PR
Sbjct: 404 RTLSARMRRRERERSPDSFSMRRT-----LPPIEGTLGLSACFL-----PNSVF--PRCS 451
Query: 101 KRPAPGS--DEEEEEEDSEEDGMVNHGDLWGSEDDADTVDDYGADSNS---------EDE 149
+R S E++ + E D +++ D++ TV+ G ++
Sbjct: 452 ERNLQESVLSEQDLMQPEEPDYLLDEMTKEAEIDNSSTVESLGETTDILNMTHIMSLNSN 511
Query: 150 EEGEALLPIERAARKQKAREAAAGIQWSEEETEDEEEEKEVTPESGPPKVEEADG 204
E+ L P+++ ++Q E +E + DE EE E K + G
Sbjct: 512 EKSLKLSPVQKQKKQQTIGELTQDTALTENDDSDEYEEMSEMKEGKACKQHVSQG 566
>gi|156104891 general transcription factor IIF, polypeptide 1, 74kDa
[Homo sapiens]
Length = 517
Score = 48.9 bits (115), Expect = 2e-05
Identities = 48/187 (25%), Positives = 77/187 (41%), Gaps = 28/187 (14%)
Query: 37 DENSKRLSSRARKRAAKRRLGSVEAPKTNKSPEAKPLPGKLPKGAVQTAGKKGPQSLFNA 96
DE+ + R R++A++ R+ +E S +A G+ G V A KK P A
Sbjct: 188 DEDEEEKEKRGRRKASELRIHDLE-DDLEMSSDASDASGE-EGGRVPKAKKKAPL----A 241
Query: 97 PRGKKRPAPGSDEEEEEEDSEEDGMVNHGDLWGSEDDADTVDDYGADSNSEDEEEGEALL 156
G+K+ ++E EDS++ GD G E D Y +D +S +EE E+
Sbjct: 242 KGGRKKKKKKGSDDEAFEDSDD------GDFEGQEVD------YMSDGSSSSQEEPESKA 289
Query: 157 PIERAARKQKAREAAAGIQWSEEETEDEEEEKEVTPESGPP----------KVEEADGGL 206
+ K + + EE + EE+KE E P EE+D
Sbjct: 290 KAPQQEEGPKGVDEQSDSSEESEEEKPPEEDKEEEEEKKAPTPQEKKRRKDSSEESDSSE 349
Query: 207 QINVDEE 213
+ ++D E
Sbjct: 350 ESDIDSE 356
>gi|148596949 nucleolar and coiled-body phosphoprotein 1 [Homo
sapiens]
Length = 699
Score = 47.8 bits (112), Expect = 4e-05
Identities = 56/258 (21%), Positives = 96/258 (37%), Gaps = 44/258 (17%)
Query: 578 AKFKKFSNSIPQSQTGNSETATPTNVDLPQVIPKSENSSQPAKKAKGAAKTKQQLQKQQH 637
AK + S+S S + E V V P+++ + P KKAK + + +
Sbjct: 121 AKASESSSSEESSDDDDEEDQKKQPVQ-KGVKPQAKAAKAPPKKAKSSDSDSDSSSEDEP 179
Query: 638 PK----KASFQKLNGISKGADSELSTVPSVTKTQASSSFQDSSQPAGKAEGIREPKVTGK 693
PK K + + +K P + +A+SS SS + ++ E K
Sbjct: 180 PKNQKPKITPVTVKAQTKAPPKPARAAPKIANGKAASS-SSSSSSSSSSDDSEEEKAAAT 238
Query: 694 LKQRSPKLQSSKKVAFLRQNAPPKGTDTQT--------------------------PAVL 727
K+ PK Q K P + + + P+
Sbjct: 239 PKKTVPKKQVVAKAPVKAATTPTRKSSSSEDSSSDEEEEQKKPMKNKPGPYSSVPPPSAP 298
Query: 728 SPSKTQATLKPKDHHQPLGRAKGVEKQQLPEQPFEKAAFQKQNDTPKGPQPPTVSPI--R 785
P K+ T PK K VEKQQ P + E ++ + + + + +PPT + +
Sbjct: 299 PPKKSLGTQPPK---------KAVEKQQ-PVESSEDSSDESDSSSEEEKKPPTKAVVSKA 348
Query: 786 SSRPPPAKRKKSQSRGNS 803
+++PPPAK+ S +S
Sbjct: 349 TTKPPPAKKAAESSSDSS 366
Score = 36.2 bits (82), Expect = 0.12
Identities = 60/256 (23%), Positives = 101/256 (39%), Gaps = 35/256 (13%)
Query: 41 KRLSSRARKRAAKRRLGSVEAPKTNKSPEAKPLPGKLPKGAVQTAGKKGPQSLFNAPRGK 100
K L+ +A +++ S E KT K A P K A+ K+ PQ R
Sbjct: 415 KLLTRKADSSSSEEESSSSEEEKTKKMV-ATTKPKATAKAALSLPAKQAPQG----SRDS 469
Query: 101 KRPAPGSDEEEEEEDSEED-----------GMVNHGDLWGSEDDADTVDDYGADSNSEDE 149
+ S EEEEE + + G + A++ + +D +SE+E
Sbjct: 470 SSDSDSSSSEEEEEKTSKSAVKKKPQKVAGGAAPSKPASAKKGKAESSNSSSSDDSSEEE 529
Query: 150 EE---GEALLPIERAARKQKAREAAAGIQWSEEETEDEEEEKE----VTPESGPPK---- 198
EE G+ P +A + A + + +E+EEEEK+ V +SG K
Sbjct: 530 EEKLKGKG-SPRPQAPKANGTSALTAQNGKAAKNSEEEEEEKKKAAVVVSKSGSLKKRKQ 588
Query: 199 ---VEEADGGLQINVD-EEPFVLPPAGEMEQDAQAPDLQRVHKRIQDIVGILRD--FGAQ 252
+EA+ + + P P + E+ A +P +RV + ++ + D F A+
Sbjct: 589 NEAAKEAETPQAKKIKLQTPNTFPKRKKGEKRASSP-FRRVREEEIEVDSRVADNSFDAK 647
Query: 253 REEGRSRSEYLNRLKK 268
R E N++ K
Sbjct: 648 RGAAGDWGERANQVLK 663
Score = 33.9 bits (76), Expect = 0.62
Identities = 46/190 (24%), Positives = 68/190 (35%), Gaps = 38/190 (20%)
Query: 38 ENSKRLSSRARKRAAKRRLGSVEAPKTNKSPEAKPLPGKLPKGAVQTAGKKGPQSLFNAP 97
E + + K+A K+ S + + E + P K K AV P P
Sbjct: 65 ERKLQANGPVAKKAKKKASSSDSEDSSEEEEEVQGPPAK--KAAV-------PAKRVGLP 115
Query: 98 RGK---KRPAPGSDEEEEEEDSEED--------GMVNHGDLWGSEDDADTVDDYGADSNS 146
GK K S EE ++D EED G+ + D +DS+S
Sbjct: 116 PGKAAAKASESSSSEESSDDDDEEDQKKQPVQKGVKPQAKAAKAPPKKAKSSDSDSDSSS 175
Query: 147 EDE---EEGEALLPIE------------RAARK---QKAREAAAGIQWSEEETEDEEEEK 188
EDE + + P+ RAA K KA +++ S + EEE+
Sbjct: 176 EDEPPKNQKPKITPVTVKAQTKAPPKPARAAPKIANGKAASSSSSSSSSSSSDDSEEEKA 235
Query: 189 EVTPESGPPK 198
TP+ PK
Sbjct: 236 AATPKKTVPK 245
Score = 33.1 bits (74), Expect = 1.1
Identities = 43/224 (19%), Positives = 78/224 (34%), Gaps = 29/224 (12%)
Query: 610 PKSENSSQPAKKA-----KGAAKTKQQLQKQQHPKK--ASFQKLNGISKGADSELSTVPS 662
P ++ ++ PAK+ K AAK + ++ QK + KG + +
Sbjct: 100 PPAKKAAVPAKRVGLPPGKAAAKASESSSSEESSDDDDEEDQKKQPVQKGVKPQAKAAKA 159
Query: 663 VTKTQASSSFQDSSQPAGKAEGIREPKVT-----------GKLKQRSPKLQSSKKVAFLR 711
K SS S + ++PK+T K + +PK+ + K +
Sbjct: 160 PPKKAKSSDSDSDSSSEDEPPKNQKPKITPVTVKAQTKAPPKPARAAPKIANGKAASSSS 219
Query: 712 QNAPPKGTD-------TQTPAVLSPSKTQATLKP-KDHHQPLGRAKGVEKQQLPEQPFEK 763
++ +D TP P K P K P ++ E E+ +K
Sbjct: 220 SSSSSSSSDDSEEEKAAATPKKTVPKKQVVAKAPVKAATTPTRKSSSSEDSSSDEEEEQK 279
Query: 764 AAFQKQNDTPKGPQPPTVSPIRSS---RPPPAKRKKSQSRGNSQ 804
+ + PP+ P + S +PP +K Q +S+
Sbjct: 280 KPMKNKPGPYSSVPPPSAPPPKKSLGTQPPKKAVEKQQPVESSE 323
Score = 32.0 bits (71), Expect = 2.4
Identities = 41/180 (22%), Positives = 59/180 (32%), Gaps = 35/180 (19%)
Query: 36 SDENSKRLSSRARKRAAKRRLGSVEA-PKTNKSPEAKPLPGKLPKGAVQ----------- 83
S E+S +K+ K + G + P + P K L + PK AV+
Sbjct: 266 SSEDSSSDEEEEQKKPMKNKPGPYSSVPPPSAPPPKKSLGTQPPKKAVEKQQPVESSEDS 325
Query: 84 -------TAGKKGPQSLFNAPRGKKRPAPGSDEEEEEEDSEEDGMVNHGDLWGSEDDADT 136
+ +K P + + +P P E DS + SEDD
Sbjct: 326 SDESDSSSEEEKKPPTKAVVSKATTKPPPAKKAAESSSDSSDSD--------SSEDDEAP 377
Query: 137 VDDYGADSNSEDEEEGEALLPIERAARK--------QKAREAAAGIQWSEEETEDEEEEK 188
G NS ++ P + A QK A SEEE+ EEEK
Sbjct: 378 SKPAGTTKNSSNKPAVTTKSPAVKPAAAPKQPVGGGQKLLTRKADSSSSEEESSSSEEEK 437
Score = 31.6 bits (70), Expect = 3.1
Identities = 22/128 (17%), Positives = 48/128 (37%), Gaps = 9/128 (7%)
Query: 96 APRGKKRPAPGSDEEEEEEDSEEDG---------MVNHGDLWGSEDDADTVDDYGADSNS 146
A + KK+ + E+ EE+ E G G G + +S+
Sbjct: 75 AKKAKKKASSSDSEDSSEEEEEVQGPPAKKAAVPAKRVGLPPGKAAAKASESSSSEESSD 134
Query: 147 EDEEEGEALLPIERAARKQKAREAAAGIQWSEEETEDEEEEKEVTPESGPPKVEEADGGL 206
+D+EE + P+++ + Q A + +++ + ++ P++ PK+
Sbjct: 135 DDDEEDQKKQPVQKGVKPQAKAAKAPPKKAKSSDSDSDSSSEDEPPKNQKPKITPVTVKA 194
Query: 207 QINVDEEP 214
Q +P
Sbjct: 195 QTKAPPKP 202
>gi|20336260 retinoblastoma protein-binding zinc finger protein
isoform b [Homo sapiens]
Length = 1682
Score = 47.8 bits (112), Expect = 4e-05
Identities = 50/200 (25%), Positives = 82/200 (41%), Gaps = 24/200 (12%)
Query: 10 EKRGPGRKARKQKGAETELVRFLPAVSDENSKRLSSRARKRAAKRRLGSVEAPKTNKSPE 69
+K+ K + K + +L P + N + + ++ K ++E P T +
Sbjct: 172 KKKSQENKNKGNKIQDIQLKTSEPDFTSANMRDSAEGPKEDEEKPSASALEQPATLQEVA 231
Query: 70 AKPLPGKLPKGAVQTAGKKGPQSLFNAPRGKKRPAPGSDEEEEEEDSEEDGMVNHGDLWG 129
++ +P +L A + P A + +EEEEEED EE+
Sbjct: 232 SQEVPPELATPAPAWEPQPEPDERLEAAACEVNDLGEEEEEEEEEDEEEE---------- 281
Query: 130 SEDDADTVDDYGADSNSEDEEEGEALLPIERAARKQKAR--EAAAGIQWSEEETEDE--E 185
EDD D EDE E EA +P E + ++ + R E + + T +E E
Sbjct: 282 -EDD--------DDDELEDEGEEEASMPNENSVKEPEIRCDEKPEDLLEEPKTTSEETLE 332
Query: 186 EEKEVTPESGPPKV-EEADG 204
+ EVTP P+ EEA+G
Sbjct: 333 DCSEVTPAMQIPRTKEEANG 352
>gi|20336258 retinoblastoma protein-binding zinc finger protein
isoform a [Homo sapiens]
Length = 1718
Score = 47.8 bits (112), Expect = 4e-05
Identities = 50/200 (25%), Positives = 82/200 (41%), Gaps = 24/200 (12%)
Query: 10 EKRGPGRKARKQKGAETELVRFLPAVSDENSKRLSSRARKRAAKRRLGSVEAPKTNKSPE 69
+K+ K + K + +L P + N + + ++ K ++E P T +
Sbjct: 172 KKKSQENKNKGNKIQDIQLKTSEPDFTSANMRDSAEGPKEDEEKPSASALEQPATLQEVA 231
Query: 70 AKPLPGKLPKGAVQTAGKKGPQSLFNAPRGKKRPAPGSDEEEEEEDSEEDGMVNHGDLWG 129
++ +P +L A + P A + +EEEEEED EE+
Sbjct: 232 SQEVPPELATPAPAWEPQPEPDERLEAAACEVNDLGEEEEEEEEEDEEEE---------- 281
Query: 130 SEDDADTVDDYGADSNSEDEEEGEALLPIERAARKQKAR--EAAAGIQWSEEETEDE--E 185
EDD D EDE E EA +P E + ++ + R E + + T +E E
Sbjct: 282 -EDD--------DDDELEDEGEEEASMPNENSVKEPEIRCDEKPEDLLEEPKTTSEETLE 332
Query: 186 EEKEVTPESGPPKV-EEADG 204
+ EVTP P+ EEA+G
Sbjct: 333 DCSEVTPAMQIPRTKEEANG 352
>gi|148763345 cell division cycle 2-like 2 isoform 4 [Homo sapiens]
Length = 770
Score = 47.0 bits (110), Expect = 7e-05
Identities = 57/233 (24%), Positives = 97/233 (41%), Gaps = 23/233 (9%)
Query: 10 EKRGPGRKARKQKGAETELVRFLPAVSDENSKRLSSRARKRAAKRR--LGSVEAPKTNKS 67
E+R R+AR++ A +R SD+ SR+ R + R LG P +
Sbjct: 187 EERRKEREARREVSAHHRTMR--EDYSDKVKASHWSRSPPRPPRERFELGDGRKPVKEEK 244
Query: 68 PEAKPLPGKLPKGAVQTAGKKGPQSLFNAPRGKKRPAPGSDEEEEEEDSEEDGMVNHGDL 127
E + L L + + K +A G + +EEEEEE+ EE+G +
Sbjct: 245 MEERDLLSDL-QDISDSERKTSSAESSSAESG----SGSEEEEEEEEEEEEEGSTSEESE 299
Query: 128 WGSEDDADTVDDYGADSNSEDEEEGEALLPIERAARKQKARE----AAAGIQWSEEETED 183
E++ + ++ G++S E+ E + E + +++ E ++ + E
Sbjct: 300 EEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERENENHLLVVPESRFDRDSGES 359
Query: 184 EEEEKEV---TPESGPPKVEEADGGLQINVDEEPFVLPPAGEMEQDAQAPDLQ 233
EE E+EV TP+S + E D V + P +LP + E P LQ
Sbjct: 360 EEAEEEVGEGTPQSS--ALTEGD-----YVPDSPALLPIELKQELPKYLPALQ 405
Score = 42.7 bits (99), Expect = 0.001
Identities = 51/231 (22%), Positives = 87/231 (37%), Gaps = 47/231 (20%)
Query: 4 KLDPTKEKRGPGRKARKQKGAETELVRFLPAVSDENSKRLSSRARKRAAKRRLGSVEAPK 63
+L+ + KR RK R+Q+ + E E +R R ++R A+R + +
Sbjct: 155 RLEQLERKRERERKMREQQKEQRE--------QKERERRAEERRKEREARREVSA----- 201
Query: 64 TNKSPEAKPLPGKLPKGAVQTAGKKGPQSLFNAPRGKKRPAPGSDEEEEEEDSEEDGMVN 123
+ + K+ + + P+ F G+K P +E+ EE D D
Sbjct: 202 -HHRTMREDYSDKVKASHWSRSPPRPPRERFELGDGRK---PVKEEKMEERDLLSDLQ-- 255
Query: 124 HGDLWGSEDDADTVDDYGADSNSEDEEEGEALLPIERAARKQKAREAAAGIQWSEEETED 183
D+ SE + + A+S S EEE EEE E+
Sbjct: 256 --DISDSERKTSSAESSSAESGSGSEEE--------------------------EEEEEE 287
Query: 184 EEEEKEVTPESGPPKVEEADGGLQINVDEEPFVLPPAGEMEQDAQAPDLQR 234
EEEE + ES + EE + + + E A E+ ++ + D +R
Sbjct: 288 EEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEER 338
>gi|148763347 cell division cycle 2-like 2 isoform 1 [Homo sapiens]
Length = 780
Score = 47.0 bits (110), Expect = 7e-05
Identities = 57/233 (24%), Positives = 97/233 (41%), Gaps = 23/233 (9%)
Query: 10 EKRGPGRKARKQKGAETELVRFLPAVSDENSKRLSSRARKRAAKRR--LGSVEAPKTNKS 67
E+R R+AR++ A +R SD+ SR+ R + R LG P +
Sbjct: 197 EERRKEREARREVSAHHRTMR--EDYSDKVKASHWSRSPPRPPRERFELGDGRKPVKEEK 254
Query: 68 PEAKPLPGKLPKGAVQTAGKKGPQSLFNAPRGKKRPAPGSDEEEEEEDSEEDGMVNHGDL 127
E + L L + + K +A G + +EEEEEE+ EE+G +
Sbjct: 255 MEERDLLSDL-QDISDSERKTSSAESSSAESG----SGSEEEEEEEEEEEEEGSTSEESE 309
Query: 128 WGSEDDADTVDDYGADSNSEDEEEGEALLPIERAARKQKARE----AAAGIQWSEEETED 183
E++ + ++ G++S E+ E + E + +++ E ++ + E
Sbjct: 310 EEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERENENHLLVVPESRFDRDSGES 369
Query: 184 EEEEKEV---TPESGPPKVEEADGGLQINVDEEPFVLPPAGEMEQDAQAPDLQ 233
EE E+EV TP+S + E D V + P +LP + E P LQ
Sbjct: 370 EEAEEEVGEGTPQSS--ALTEGD-----YVPDSPALLPIELKQELPKYLPALQ 415
Score = 42.7 bits (99), Expect = 0.001
Identities = 51/231 (22%), Positives = 87/231 (37%), Gaps = 47/231 (20%)
Query: 4 KLDPTKEKRGPGRKARKQKGAETELVRFLPAVSDENSKRLSSRARKRAAKRRLGSVEAPK 63
+L+ + KR RK R+Q+ + E E +R R ++R A+R + +
Sbjct: 165 RLEQLERKRERERKMREQQKEQRE--------QKERERRAEERRKEREARREVSA----- 211
Query: 64 TNKSPEAKPLPGKLPKGAVQTAGKKGPQSLFNAPRGKKRPAPGSDEEEEEEDSEEDGMVN 123
+ + K+ + + P+ F G+K P +E+ EE D D
Sbjct: 212 -HHRTMREDYSDKVKASHWSRSPPRPPRERFELGDGRK---PVKEEKMEERDLLSDLQ-- 265
Query: 124 HGDLWGSEDDADTVDDYGADSNSEDEEEGEALLPIERAARKQKAREAAAGIQWSEEETED 183
D+ SE + + A+S S EEE EEE E+
Sbjct: 266 --DISDSERKTSSAESSSAESGSGSEEE--------------------------EEEEEE 297
Query: 184 EEEEKEVTPESGPPKVEEADGGLQINVDEEPFVLPPAGEMEQDAQAPDLQR 234
EEEE + ES + EE + + + E A E+ ++ + D +R
Sbjct: 298 EEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEER 348
>gi|69354671 ATP-binding cassette, sub-family F, member 1 isoform a
[Homo sapiens]
Length = 845
Score = 45.8 bits (107), Expect = 2e-04
Identities = 50/187 (26%), Positives = 77/187 (41%), Gaps = 14/187 (7%)
Query: 9 KEKRGPGRKARKQKGAETELVRFLPAVSDENS-KRLSSRARKRAAKRRLGSVEAPKTNKS 67
KE++ ++ +++K +T R V D+ K L R +K L + + ++
Sbjct: 62 KEQQQQQQQQQQKKKRDTRKGRRKKDVDDDGEEKELMERLKK------LSVPTSDEEDEV 115
Query: 68 PEAKPLPGKLPKGAVQTAGKKGPQSLFNAPRGKKRPAPGSDEEEE-----EEDSEEDGMV 122
P KP GK KG A QS K P P E+ E+ +
Sbjct: 116 PAPKPRGGKKTKGGNVFAALIQDQSEEEEEEEKHPPKPAKPEKNRINKAVSEEQQPALKG 175
Query: 123 NHGDLWGSEDDADTVDDYGADSNSEDEEEGEALLPIERAARKQKAREAAAGIQWSEEETE 182
G S+ A + + A N E+++E E + E+ KQ +A Q SEEE E
Sbjct: 176 KKGKEEKSKGKAKPQNKFAALDNEEEDKEEEIIK--EKEPPKQGKEKAKKAEQGSEEEGE 233
Query: 183 DEEEEKE 189
EEEE+E
Sbjct: 234 GEEEEEE 240
Score = 33.5 bits (75), Expect = 0.81
Identities = 40/193 (20%), Positives = 79/193 (40%), Gaps = 22/193 (11%)
Query: 20 KQKGAETELVRFLPAVSDENSKRLSSRARKRAAKRRLGSVEAPKTNKSPEAKPLPGKLPK 79
KQ G E ++++ + ++ + R +R+ + E K L +L K
Sbjct: 50 KQAGEEEKVLKEKEQQQQQQQQQQKKKRDTRKGRRK------KDVDDDGEEKELMERLKK 103
Query: 80 GAVQTAGKKGPQSLFNAPRGKKRPAPGS-------DEEEEEEDSEEDGMVNHGDLWGSED 132
+V T+ ++ PRG K+ G+ D+ EEEE+ E+ +
Sbjct: 104 LSVPTSDEEDEVPA-PKPRGGKKTKGGNVFAALIQDQSEEEEEEEKHPPKPAKPEKNRIN 162
Query: 133 DADTVDDYGADSNSEDEEEGEALLPIERAARKQKAREAAAGIQWSEEETEDEEEEKEVTP 192
A + + A + +EE ++ K K + A + EE+ E+E +++ P
Sbjct: 163 KAVSEEQQPALKGKKGKEE--------KSKGKAKPQNKFAALDNEEEDKEEEIIKEKEPP 214
Query: 193 ESGPPKVEEADGG 205
+ G K ++A+ G
Sbjct: 215 KQGKEKAKKAEQG 227
Score = 32.3 bits (72), Expect = 1.8
Identities = 28/128 (21%), Positives = 52/128 (40%), Gaps = 19/128 (14%)
Query: 609 IPKSENSSQ-PAKKAKGAAKTK--------------QQLQKQQHPKKASFQKLNGISKGA 653
+P S+ + PA K +G KTK ++ ++++HP K + + N I+K
Sbjct: 106 VPTSDEEDEVPAPKPRGGKKTKGGNVFAALIQDQSEEEEEEEKHPPKPAKPEKNRINKAV 165
Query: 654 DSELSTVPSVTKTQASSSFQDSSQPAGKAEGI---REPKVTGKLKQRSPKLQSSKKVAFL 710
E K + S + ++P K + E K +K++ P Q +K
Sbjct: 166 SEEQQPALKGKKGKEEKS-KGKAKPQNKFAALDNEEEDKEEEIIKEKEPPKQGKEKAKKA 224
Query: 711 RQNAPPKG 718
Q + +G
Sbjct: 225 EQGSEEEG 232
>gi|155030232 proline, glutamic acid and leucine rich protein 1 [Homo
sapiens]
Length = 1130
Score = 45.8 bits (107), Expect = 2e-04
Identities = 55/221 (24%), Positives = 80/221 (36%), Gaps = 74/221 (33%)
Query: 62 PKTNKSPEAKPLPGKLPKGAVQTAGKKGPQSLFNAP-----RGKKRPAPGSDEEEEEEDS 116
P P P P +P+G T G GP +L +EEEEEE+
Sbjct: 846 PPPVPGPVTLPPPQLVPEG---TPGGGGPPALEEDLTVININSSDEEEEEEEEEEEEEEE 902
Query: 117 EEDGMVNHGDLWGSEDDADTVDDYGADSNSEDEEEGEALLPIERAARKQKAREAAAGIQW 176
EE+ E+D + ++ + E+EEE E ++ E G
Sbjct: 903 EEE----------EEEDFEEEEEDEEEYFEEEEEEEEEF---------EEEFEEEEGELE 943
Query: 177 SEEETEDEEEEKE-----------------------------VTPESGPPKVE---EADG 204
EEE EDEEEE+E + P PPKV+ E +
Sbjct: 944 EEEEEEDEEEEEELEEVEDLEFGTAGGEVEEGAPPPPTLPPALPPPESPPKVQPEPEPEP 1003
Query: 205 GLQINVDE---------------EPFVLPPAGEMEQDAQAP 230
GL + V+E P LP GE+E++ ++P
Sbjct: 1004 GLLLEVEEPGTEEERGADTAPTLAPEALPSQGEVEREGESP 1044
Score = 41.2 bits (95), Expect = 0.004
Identities = 40/140 (28%), Positives = 59/140 (42%), Gaps = 18/140 (12%)
Query: 108 DEEEEEEDSEEDGMVNHGDLWGSEDDADT--------VDDYGADSNSEDEEEGE------ 153
+EEEEEE+ EE+ G+L E++ D V+D + + EEG
Sbjct: 923 EEEEEEEEFEEEFEEEEGELEEEEEEEDEEEEEELEEVEDLEFGTAGGEVEEGAPPPPTL 982
Query: 154 --ALLPIERAARKQKAREAAAGIQWSEEETEDEEEEKEVTPESGPPKVEEADGGLQINVD 211
AL P E + Q E G+ EE EEE T + P+ + G ++
Sbjct: 983 PPALPPPESPPKVQPEPEPEPGLLLEVEEPGTEEERGADTAPTLAPEALPSQGEVE-REG 1041
Query: 212 EEPFVLPPAGEM-EQDAQAP 230
E P PP E+ E++ AP
Sbjct: 1042 ESPAAGPPPQELVEEEPSAP 1061
Score = 32.3 bits (72), Expect = 1.8
Identities = 40/153 (26%), Positives = 58/153 (37%), Gaps = 33/153 (21%)
Query: 103 PAPGSDEEEEEEDSEEDGMVNHGDLWGSE-----DDADTVDDYGADSNSEDEEEGEALLP 157
P P S + + E E G++ + G+E D A T+ S E E EGE+ P
Sbjct: 987 PPPESPPKVQPEPEPEPGLLLEVEEPGTEEERGADTAPTLAPEALPSQGEVEREGES--P 1044
Query: 158 IERAARKQKAREA-AAGIQWSEEETEDEEEEKEVTPESGPPKVEEADGGLQINVDEEPFV 216
++ E +A EEETED ++ + PE+
Sbjct: 1045 AAGPPPQELVEEEPSAPPTLLEEETEDGSDKVQPPPET---------------------- 1082
Query: 217 LPPAGEMEQDAQAPDLQRVHKRIQDIVGILRDF 249
P EME + +A LQ K D +L DF
Sbjct: 1083 -PAEEEMETETEAEALQ--EKEQDDTAAMLADF 1112
>gi|117414137 retinitis pigmentosa 1-like 1 [Homo sapiens]
Length = 2400
Score = 45.1 bits (105), Expect = 3e-04
Identities = 39/191 (20%), Positives = 82/191 (42%), Gaps = 5/191 (2%)
Query: 57 GSVEAPKTNKSPEAKPLPGKLPKGAVQTAGK--KGPQSLFNA-PRGKKRPAPGSDEEEEE 113
G + + PE++ + +G Q + + P++ + P + AP +++E +
Sbjct: 1858 GDAQEAEGEAQPESEDVEAPEAEGEAQPESEDVETPEAEWEVQPESEGAEAPEAEKEAQP 1917
Query: 114 EDSEEDGMVNHGDLWGSEDDADTVDDYGADSNSEDEEEGEALLPIERAARKQKAREAAAG 173
E + + G+ + A+ + A +E + + E+ + IE +++A+ +
Sbjct: 1918 ETESVEALETEGEDEPESEGAEAQEAEEAAQEAEGQTQPESEV-IESQEAEEEAQPESED 1976
Query: 174 IQWSEEETEDEEEEKEVTPESGPPKVEEADGGLQINVDEEPFVLPPAGEMEQDAQAPDLQ 233
++ E E E +E E E PES + EA+G +Q +EE E + ++ + Q
Sbjct: 1977 VEALEVEVETQEAEGEAQPESEDVEAPEAEGEMQ-EAEEEAQPESDGVEAQPKSEGEEAQ 2035
Query: 234 RVHKRIQDIVG 244
V Q G
Sbjct: 2036 EVEGETQKTEG 2046
Score = 43.5 bits (101), Expect = 8e-04
Identities = 51/206 (24%), Positives = 83/206 (40%), Gaps = 23/206 (11%)
Query: 106 GSDEEEEEEDSEEDGMVNHGDLWGS-EDDADTVDDYGADSNSEDEEEGEALLPIERAARK 164
GS+ E E++ E G+ G+ G D + A +D + + IE +
Sbjct: 1784 GSELGEAEQEGE--GISERGETGGQGSGHEDNLQGEAAAGGDQDPGQSDGAEGIEAPEAE 1841
Query: 165 QKAREAAAGIQWSEEETEDEEEEKEVTPESGPPKVEEADGGLQINVDEEPFVLPPAGEME 224
+A+ + G++ E E + +E E E PES + EA+G Q E V P E E
Sbjct: 1842 GEAQPESEGVEAPEAEGDAQEAEGEAQPESEDVEAPEAEGEAQ---PESEDVETPEAEWE 1898
Query: 225 -----QDAQAPDLQRVHKRIQDIVGILRDFGAQREEGRSRSEYLNRLKKDLAIYYSYGDF 279
+ A+AP+ ++ + + V L G E SE + + A + G
Sbjct: 1899 VQPESEGAEAPEAEKEAQPETESVEALETEG----EDEPESEGAEAQEAEEAAQEAEG-- 1952
Query: 280 LLGKLMDLFPLSELVEFLEANEVPRP 305
P SE++E EA E +P
Sbjct: 1953 ------QTQPESEVIESQEAEEEAQP 1972
Score = 43.5 bits (101), Expect = 8e-04
Identities = 51/180 (28%), Positives = 78/180 (43%), Gaps = 25/180 (13%)
Query: 59 VEAPKTNKSPEAKPLPGKLPKGAVQTAGKKGPQSLFNAPRGKKRPAPGSDEEEEEEDSEE 118
VEA ++ EA+ + G+ K T G P+S G + P E EEE E
Sbjct: 2023 VEAQPKSEGEEAQEVEGETQK----TEGDAQPES-----DGVEAP------EAEEEAQEA 2067
Query: 119 DGMVNHGDLWGSEDDADTVDDYGADSNSEDEEEGEALLPIERAARKQK---AREAAAGIQ 175
+G V + + +++ VD A+ ++ E EG E A+K + A E Q
Sbjct: 2068 EGEVQEAE-GEAHPESEDVDAQEAEGEAQPESEGVEAPEAEGEAQKAEGIEAPETEGEAQ 2126
Query: 176 WSEEETEDEEEEKEVTPESGPPKVEEADGGLQINVDEEPFVLPPAGEMEQDAQAPDLQRV 235
E E E E E PES + ++A+G Q + A E E++AQ P+L+ V
Sbjct: 2127 PESEGIEAPEAEGEAQPESEGVEAQDAEGEAQPESEG-----IEAQEAEEEAQ-PELEGV 2180
Score = 39.7 bits (91), Expect = 0.011
Identities = 56/233 (24%), Positives = 95/233 (40%), Gaps = 31/233 (13%)
Query: 10 EKRGPGRKARKQKGAETELVRFLPAVSDENSKRLSSRARKRA--AKRRLGSVEAPKTNKS 67
E G ++A ++ E++ V P E ++ + +K A+ VEAP+ +
Sbjct: 2004 EAEGEMQEAEEEAQPESDGVEAQPKSEGEEAQEVEGETQKTEGDAQPESDGVEAPEAEEE 2063
Query: 68 PEAKPLPGKLPKGAVQTA-GKKGPQSLFNAPRGKKRPAPGSDEEEEEEDSEEDGMVNHGD 126
+ +G VQ A G+ P+S + E E E E +G V +
Sbjct: 2064 AQEA-------EGEVQEAEGEAHPES----------EDVDAQEAEGEAQPESEG-VEAPE 2105
Query: 127 LWGSEDDADTVDDYGADSNSEDEEEGEALLPIERAARKQ----KAREAAAGIQWSEEETE 182
G A+ ++ + ++ E EG E A+ + +A++A Q E E
Sbjct: 2106 AEGEAQKAEGIEAPETEGEAQPESEGIEAPEAEGEAQPESEGVEAQDAEGEAQPESEGIE 2165
Query: 183 DEEEEKEVTPESGPPKVEEADGGLQINVDEEPFVLPPAGEMEQDAQAPDLQRV 235
+E E+E PE + EA+G Q + E P E E +AQ P+L+ V
Sbjct: 2166 AQEAEEEAQPELEGVEAPEAEGEAQ--PESEGIEAP---EAEGEAQ-PELEGV 2212
Score = 32.0 bits (71), Expect = 2.4
Identities = 35/146 (23%), Positives = 55/146 (37%), Gaps = 20/146 (13%)
Query: 100 KKRPAPGSDEEEEEEDSEEDGMVNHGDLWGSE-DDADTVDDYGADSNSEDEEEGEALLPI 158
K+ P G E EE +E+G+ G + G E +A + D G+ + +EE
Sbjct: 1378 KEGPEGGLQGEALEEGLKEEGLPEEGSVHGQELSEASSPDGKGSQEDDPVQEE------- 1430
Query: 159 ERAARKQKAREAAAGIQWSEEETEDEEEEKEVTPESGPPKVEEADGGLQINVDEEPFVLP 218
+ R +A+ E TE+ E E+ P E G Q+ E P
Sbjct: 1431 ------EAGRASASAEPCPAEGTEEPTEPPSHLSET-DPSASERQSGSQL---EPGLEKP 1480
Query: 219 PAGEM--EQDAQAPDLQRVHKRIQDI 242
P M ++ QA Q +R +
Sbjct: 1481 PGATMMGQEHTQAQPTQGAAERSSSV 1506
>gi|4503351 DNA (cytosine-5-)-methyltransferase 1 isoform b [Homo
sapiens]
Length = 1616
Score = 44.7 bits (104), Expect = 4e-04
Identities = 52/205 (25%), Positives = 86/205 (41%), Gaps = 50/205 (24%)
Query: 34 AVSDENSKRLSSRARKRAAKRRLGSVEA------------PKTNKSP-EAKPLPGKLPKG 80
A + E + RL + + R+ RR+G +A P+ +KS EAKP P P+
Sbjct: 98 AYNREVNGRLENGNQARSEARRVGMADANSPPKPLSKPRTPRRSKSDGEAKPEPSPSPRI 157
Query: 81 AVQTAGKKGPQSLFNAPRGKKRPAPGSDEEEEEEDSEEDGMVNHGDLWGSEDDADTVDDY 140
++ + S F K++P +EE E ++ D + E+D D
Sbjct: 158 TRKSTRQTTITSHFAKGPAKRKP------QEESERAKSDESIK-------EEDKD----- 199
Query: 141 GADSNSEDEEEGEALLPIERAARKQKARE---AAAGIQWSEEETEDEEEEKEVTPESGPP 197
+E+ + ER AR A E A +G + +EE DE+EEK + ++ P
Sbjct: 200 -------QDEKRRRVTSRERVARPLPAEEPERAKSGTRTEKEEERDEKEEKRLRSQTKEP 252
Query: 198 KVE---------EADGGLQINVDEE 213
+ EA G+Q + DE+
Sbjct: 253 TPKQKLKEEPDREARAGVQADEDED 277
Score = 31.2 bits (69), Expect = 4.0
Identities = 44/223 (19%), Positives = 82/223 (36%), Gaps = 33/223 (14%)
Query: 11 KRGPGRKARKQKGAETELVRFLPAVSDENSKRLSSRARKRAAKRRLGSVEAPKTNKSPEA 70
KR P ++ + K E+ ++ DE +R++SR R A
Sbjct: 177 KRKPQEESERAKSDES--IKEEDKDQDEKRRRVTSRERV--------------------A 214
Query: 71 KPLPGKLPKGAVQTAGKKGPQSLFNAPRGKKRPAPGSDEEEEEEDSEEDGMVNHGDLWGS 130
+PLP + P+ A + + + R +++ E D G
Sbjct: 215 RPLPAEEPERAKSGTRTEKEEERDEKEEKRLRSQTKEPTPKQKLKEEPDREARAGVQADE 274
Query: 131 EDDADTVDDYGADSNSEDEEEGEALLPIERAARKQKAREAAAGIQWSEEETEDEEEEKEV 190
++D D D+ S +D L +R +++ + I ++E E EE+ ++
Sbjct: 275 DEDGDEKDEKKHRSQPKD-------LAAKRRPEEKEPEKVNPQISDEKDEDEKEEKRRKT 327
Query: 191 TPESGPPKVEEADGGLQINVDEEPFVLPPAGEMEQDAQAPDLQ 233
TP+ P + + A +N P P + Q PDL+
Sbjct: 328 TPKE-PTEKKMARAKTVMNSKTHP---PKCIQCGQYLDDPDLK 366
>gi|16332372 cell division cycle 2-like 1 (PITSLRE proteins) isoform
9 [Homo sapiens]
Length = 771
Score = 44.7 bits (104), Expect = 4e-04
Identities = 56/233 (24%), Positives = 96/233 (41%), Gaps = 23/233 (9%)
Query: 10 EKRGPGRKARKQKGAETELVRFLPAVSDENSKRLSSRARKRAAKRR--LGSVEAPKTNKS 67
E+R R+AR++ A +R SD+ SR+ R + R LG P +
Sbjct: 188 EERRKEREARREVSAHHRTMR--EDYSDKVKASHWSRSPPRPPRERFELGDGRKPVKEEK 245
Query: 68 PEAKPLPGKLPKGAVQTAGKKGPQSLFNAPRGKKRPAPGSDEEEEEEDSEEDGMVNHGDL 127
E + L L + + K +A G + +EEEEEE+ EE+G +
Sbjct: 246 MEERDLLSDL-QDISDSERKTSSAESSSAESG----SGSEEEEEEEEEEEEEGSTSEESE 300
Query: 128 WGSEDDADTVDDYGADSNSEDEEEGEALLPIERAARKQKARE----AAAGIQWSEEETED 183
E++ + ++ G++S E+ E + E + +++ E ++ + E
Sbjct: 301 EEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERENENHLLVVPESRFDRDSGES 360
Query: 184 EEEEKEV---TPESGPPKVEEADGGLQINVDEEPFVLPPAGEMEQDAQAPDLQ 233
EE E+EV TP+S + E D V + P + P + E P LQ
Sbjct: 361 EEAEEEVGEGTPQSS--ALTEGD-----YVPDSPALSPIELKQELPKYLPALQ 406
Score = 42.7 bits (99), Expect = 0.001
Identities = 51/231 (22%), Positives = 87/231 (37%), Gaps = 47/231 (20%)
Query: 4 KLDPTKEKRGPGRKARKQKGAETELVRFLPAVSDENSKRLSSRARKRAAKRRLGSVEAPK 63
+L+ + KR RK R+Q+ + E E +R R ++R A+R + +
Sbjct: 156 RLEQLERKRERERKMREQQKEQRE--------QKERERRAEERRKEREARREVSA----- 202
Query: 64 TNKSPEAKPLPGKLPKGAVQTAGKKGPQSLFNAPRGKKRPAPGSDEEEEEEDSEEDGMVN 123
+ + K+ + + P+ F G+K P +E+ EE D D
Sbjct: 203 -HHRTMREDYSDKVKASHWSRSPPRPPRERFELGDGRK---PVKEEKMEERDLLSDLQ-- 256
Query: 124 HGDLWGSEDDADTVDDYGADSNSEDEEEGEALLPIERAARKQKAREAAAGIQWSEEETED 183
D+ SE + + A+S S EEE EEE E+
Sbjct: 257 --DISDSERKTSSAESSSAESGSGSEEE--------------------------EEEEEE 288
Query: 184 EEEEKEVTPESGPPKVEEADGGLQINVDEEPFVLPPAGEMEQDAQAPDLQR 234
EEEE + ES + EE + + + E A E+ ++ + D +R
Sbjct: 289 EEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEER 339
>gi|16332370 cell division cycle 2-like 1 (PITSLRE proteins) isoform
8 [Homo sapiens]
Length = 780
Score = 44.7 bits (104), Expect = 4e-04
Identities = 56/233 (24%), Positives = 96/233 (41%), Gaps = 23/233 (9%)
Query: 10 EKRGPGRKARKQKGAETELVRFLPAVSDENSKRLSSRARKRAAKRR--LGSVEAPKTNKS 67
E+R R+AR++ A +R SD+ SR+ R + R LG P +
Sbjct: 197 EERRKEREARREVSAHHRTMR--EDYSDKVKASHWSRSPPRPPRERFELGDGRKPVKEEK 254
Query: 68 PEAKPLPGKLPKGAVQTAGKKGPQSLFNAPRGKKRPAPGSDEEEEEEDSEEDGMVNHGDL 127
E + L L + + K +A G + +EEEEEE+ EE+G +
Sbjct: 255 MEERDLLSDL-QDISDSERKTSSAESSSAESG----SGSEEEEEEEEEEEEEGSTSEESE 309
Query: 128 WGSEDDADTVDDYGADSNSEDEEEGEALLPIERAARKQKARE----AAAGIQWSEEETED 183
E++ + ++ G++S E+ E + E + +++ E ++ + E
Sbjct: 310 EEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERENENHLLVVPESRFDRDSGES 369
Query: 184 EEEEKEV---TPESGPPKVEEADGGLQINVDEEPFVLPPAGEMEQDAQAPDLQ 233
EE E+EV TP+S + E D V + P + P + E P LQ
Sbjct: 370 EEAEEEVGEGTPQSS--ALTEGD-----YVPDSPALSPIELKQELPKYLPALQ 415
Score = 42.7 bits (99), Expect = 0.001
Identities = 51/231 (22%), Positives = 87/231 (37%), Gaps = 47/231 (20%)
Query: 4 KLDPTKEKRGPGRKARKQKGAETELVRFLPAVSDENSKRLSSRARKRAAKRRLGSVEAPK 63
+L+ + KR RK R+Q+ + E E +R R ++R A+R + +
Sbjct: 165 RLEQLERKRERERKMREQQKEQRE--------QKERERRAEERRKEREARREVSA----- 211
Query: 64 TNKSPEAKPLPGKLPKGAVQTAGKKGPQSLFNAPRGKKRPAPGSDEEEEEEDSEEDGMVN 123
+ + K+ + + P+ F G+K P +E+ EE D D
Sbjct: 212 -HHRTMREDYSDKVKASHWSRSPPRPPRERFELGDGRK---PVKEEKMEERDLLSDLQ-- 265
Query: 124 HGDLWGSEDDADTVDDYGADSNSEDEEEGEALLPIERAARKQKAREAAAGIQWSEEETED 183
D+ SE + + A+S S EEE EEE E+
Sbjct: 266 --DISDSERKTSSAESSSAESGSGSEEE--------------------------EEEEEE 297
Query: 184 EEEEKEVTPESGPPKVEEADGGLQINVDEEPFVLPPAGEMEQDAQAPDLQR 234
EEEE + ES + EE + + + E A E+ ++ + D +R
Sbjct: 298 EEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEER 348
>gi|16332364 cell division cycle 2-like 1 (PITSLRE proteins) isoform
5 [Homo sapiens]
Length = 748
Score = 44.7 bits (104), Expect = 4e-04
Identities = 56/233 (24%), Positives = 96/233 (41%), Gaps = 23/233 (9%)
Query: 10 EKRGPGRKARKQKGAETELVRFLPAVSDENSKRLSSRARKRAAKRR--LGSVEAPKTNKS 67
E+R R+AR++ A +R SD+ SR+ R + R LG P +
Sbjct: 165 EERRKEREARREVSAHHRTMR--EDYSDKVKASHWSRSPPRPPRERFELGDGRKPVKEEK 222
Query: 68 PEAKPLPGKLPKGAVQTAGKKGPQSLFNAPRGKKRPAPGSDEEEEEEDSEEDGMVNHGDL 127
E + L L + + K +A G + +EEEEEE+ EE+G +
Sbjct: 223 MEERDLLSDL-QDISDSERKTSSAESSSAESG----SGSEEEEEEEEEEEEEGSTSEESE 277
Query: 128 WGSEDDADTVDDYGADSNSEDEEEGEALLPIERAARKQKARE----AAAGIQWSEEETED 183
E++ + ++ G++S E+ E + E + +++ E ++ + E
Sbjct: 278 EEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERENENHLLVVPESRFDRDSGES 337
Query: 184 EEEEKEV---TPESGPPKVEEADGGLQINVDEEPFVLPPAGEMEQDAQAPDLQ 233
EE E+EV TP+S + E D V + P + P + E P LQ
Sbjct: 338 EEAEEEVGEGTPQSS--ALTEGD-----YVPDSPALSPIELKQELPKYLPALQ 383
Score = 42.7 bits (99), Expect = 0.001
Identities = 51/231 (22%), Positives = 87/231 (37%), Gaps = 47/231 (20%)
Query: 4 KLDPTKEKRGPGRKARKQKGAETELVRFLPAVSDENSKRLSSRARKRAAKRRLGSVEAPK 63
+L+ + KR RK R+Q+ + E E +R R ++R A+R + +
Sbjct: 133 RLEQLERKRERERKMREQQKEQRE--------QKERERRAEERRKEREARREVSA----- 179
Query: 64 TNKSPEAKPLPGKLPKGAVQTAGKKGPQSLFNAPRGKKRPAPGSDEEEEEEDSEEDGMVN 123
+ + K+ + + P+ F G+K P +E+ EE D D
Sbjct: 180 -HHRTMREDYSDKVKASHWSRSPPRPPRERFELGDGRK---PVKEEKMEERDLLSDLQ-- 233
Query: 124 HGDLWGSEDDADTVDDYGADSNSEDEEEGEALLPIERAARKQKAREAAAGIQWSEEETED 183
D+ SE + + A+S S EEE EEE E+
Sbjct: 234 --DISDSERKTSSAESSSAESGSGSEEE--------------------------EEEEEE 265
Query: 184 EEEEKEVTPESGPPKVEEADGGLQINVDEEPFVLPPAGEMEQDAQAPDLQR 234
EEEE + ES + EE + + + E A E+ ++ + D +R
Sbjct: 266 EEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEER 316
>gi|16332362 cell division cycle 2-like 1 (PITSLRE proteins) isoform
4 [Homo sapiens]
Length = 737
Score = 44.7 bits (104), Expect = 4e-04
Identities = 56/233 (24%), Positives = 96/233 (41%), Gaps = 23/233 (9%)
Query: 10 EKRGPGRKARKQKGAETELVRFLPAVSDENSKRLSSRARKRAAKRR--LGSVEAPKTNKS 67
E+R R+AR++ A +R SD+ SR+ R + R LG P +
Sbjct: 154 EERRKEREARREVSAHHRTMR--EDYSDKVKASHWSRSPPRPPRERFELGDGRKPVKEEK 211
Query: 68 PEAKPLPGKLPKGAVQTAGKKGPQSLFNAPRGKKRPAPGSDEEEEEEDSEEDGMVNHGDL 127
E + L L + + K +A G + +EEEEEE+ EE+G +
Sbjct: 212 MEERDLLSDL-QDISDSERKTSSAESSSAESG----SGSEEEEEEEEEEEEEGSTSEESE 266
Query: 128 WGSEDDADTVDDYGADSNSEDEEEGEALLPIERAARKQKARE----AAAGIQWSEEETED 183
E++ + ++ G++S E+ E + E + +++ E ++ + E
Sbjct: 267 EEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERENENHLLVVPESRFDRDSGES 326
Query: 184 EEEEKEV---TPESGPPKVEEADGGLQINVDEEPFVLPPAGEMEQDAQAPDLQ 233
EE E+EV TP+S + E D V + P + P + E P LQ
Sbjct: 327 EEAEEEVGEGTPQSS--ALTEGD-----YVPDSPALSPIELKQELPKYLPALQ 372
Score = 42.7 bits (99), Expect = 0.001
Identities = 51/231 (22%), Positives = 87/231 (37%), Gaps = 47/231 (20%)
Query: 4 KLDPTKEKRGPGRKARKQKGAETELVRFLPAVSDENSKRLSSRARKRAAKRRLGSVEAPK 63
+L+ + KR RK R+Q+ + E E +R R ++R A+R + +
Sbjct: 122 RLEQLERKRERERKMREQQKEQRE--------QKERERRAEERRKEREARREVSA----- 168
Query: 64 TNKSPEAKPLPGKLPKGAVQTAGKKGPQSLFNAPRGKKRPAPGSDEEEEEEDSEEDGMVN 123
+ + K+ + + P+ F G+K P +E+ EE D D
Sbjct: 169 -HHRTMREDYSDKVKASHWSRSPPRPPRERFELGDGRK---PVKEEKMEERDLLSDLQ-- 222
Query: 124 HGDLWGSEDDADTVDDYGADSNSEDEEEGEALLPIERAARKQKAREAAAGIQWSEEETED 183
D+ SE + + A+S S EEE EEE E+
Sbjct: 223 --DISDSERKTSSAESSSAESGSGSEEE--------------------------EEEEEE 254
Query: 184 EEEEKEVTPESGPPKVEEADGGLQINVDEEPFVLPPAGEMEQDAQAPDLQR 234
EEEE + ES + EE + + + E A E+ ++ + D +R
Sbjct: 255 EEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEER 305
>gi|16332358 cell division cycle 2-like 1 (PITSLRE proteins) isoform
2 [Homo sapiens]
Length = 782
Score = 44.7 bits (104), Expect = 4e-04
Identities = 56/233 (24%), Positives = 96/233 (41%), Gaps = 23/233 (9%)
Query: 10 EKRGPGRKARKQKGAETELVRFLPAVSDENSKRLSSRARKRAAKRR--LGSVEAPKTNKS 67
E+R R+AR++ A +R SD+ SR+ R + R LG P +
Sbjct: 199 EERRKEREARREVSAHHRTMR--EDYSDKVKASHWSRSPPRPPRERFELGDGRKPVKEEK 256
Query: 68 PEAKPLPGKLPKGAVQTAGKKGPQSLFNAPRGKKRPAPGSDEEEEEEDSEEDGMVNHGDL 127
E + L L + + K +A G + +EEEEEE+ EE+G +
Sbjct: 257 MEERDLLSDL-QDISDSERKTSSAESSSAESG----SGSEEEEEEEEEEEEEGSTSEESE 311
Query: 128 WGSEDDADTVDDYGADSNSEDEEEGEALLPIERAARKQKARE----AAAGIQWSEEETED 183
E++ + ++ G++S E+ E + E + +++ E ++ + E
Sbjct: 312 EEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERENENHLLVVPESRFDRDSGES 371
Query: 184 EEEEKEV---TPESGPPKVEEADGGLQINVDEEPFVLPPAGEMEQDAQAPDLQ 233
EE E+EV TP+S + E D V + P + P + E P LQ
Sbjct: 372 EEAEEEVGEGTPQSS--ALTEGD-----YVPDSPALSPIELKQELPKYLPALQ 417
Score = 42.7 bits (99), Expect = 0.001
Identities = 51/231 (22%), Positives = 87/231 (37%), Gaps = 47/231 (20%)
Query: 4 KLDPTKEKRGPGRKARKQKGAETELVRFLPAVSDENSKRLSSRARKRAAKRRLGSVEAPK 63
+L+ + KR RK R+Q+ + E E +R R ++R A+R + +
Sbjct: 167 RLEQLERKRERERKMREQQKEQRE--------QKERERRAEERRKEREARREVSA----- 213
Query: 64 TNKSPEAKPLPGKLPKGAVQTAGKKGPQSLFNAPRGKKRPAPGSDEEEEEEDSEEDGMVN 123
+ + K+ + + P+ F G+K P +E+ EE D D
Sbjct: 214 -HHRTMREDYSDKVKASHWSRSPPRPPRERFELGDGRK---PVKEEKMEERDLLSDLQ-- 267
Query: 124 HGDLWGSEDDADTVDDYGADSNSEDEEEGEALLPIERAARKQKAREAAAGIQWSEEETED 183
D+ SE + + A+S S EEE EEE E+
Sbjct: 268 --DISDSERKTSSAESSSAESGSGSEEE--------------------------EEEEEE 299
Query: 184 EEEEKEVTPESGPPKVEEADGGLQINVDEEPFVLPPAGEMEQDAQAPDLQR 234
EEEE + ES + EE + + + E A E+ ++ + D +R
Sbjct: 300 EEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEER 350
>gi|150170670 piccolo isoform 2 [Homo sapiens]
Length = 4935
Score = 44.3 bits (103), Expect = 5e-04
Identities = 59/208 (28%), Positives = 82/208 (39%), Gaps = 28/208 (13%)
Query: 588 PQSQTGNSETATPTNVDLPQVIPKSENSSQPAKKAKGAAKTKQQLQKQQHPKKASFQKLN 647
P Q G ++ T V P+ + + PAK A G KT Q Q P K Q+
Sbjct: 401 PAQQPGPAKPPTQ-QVGTPKPLAQQPGLQSPAK-APGPTKTPVQ---QPGPGKIPAQQAG 455
Query: 648 GISKGADSELSTVPSVTKTQASSSFQDSSQPAGKAEGIREPKVTGKLKQRSPKLQSSKKV 707
G S T P+ +Q + Q G A+ P+ G K S + S+K
Sbjct: 456 ---PGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKP--PPQQPGSAKPPSQQPGSTKP- 509
Query: 708 AFLRQNAPPKGTDTQTPAVLSPSKTQATLKPKDHHQPLGRAKGVEKQQLPEQPFEKAAFQ 767
PP Q P PS Q QP G AK +Q P +P + + +
Sbjct: 510 -------PP-----QQPGPAKPSPQQPGSTKPPSQQP-GSAKPSAQQPSPAKPSAQQSTK 556
Query: 768 KQNDTPKGP--QPPTVSPIRSSRPPPAK 793
+ T G QPPTVSP S++ PP++
Sbjct: 557 PVSQTGSGKPLQPPTVSP--SAKQPPSQ 582
Score = 40.0 bits (92), Expect = 0.009
Identities = 58/241 (24%), Positives = 89/241 (36%), Gaps = 24/241 (9%)
Query: 584 SNSIPQSQTGNSETATPTNVDL---PQVIPKSENSSQPAKKAKGAAKTKQ-----QLQKQ 635
S S PQ Q + + DL P+ QP +AK KQ L K
Sbjct: 673 SKSSPQPQQTSPKKDAAPKQDLSKAPEPKKPPPLVKQPTLHGSPSAKAKQPPEADSLSKP 732
Query: 636 QHPKKASFQKLNGISKGADSELS----TVPSVTKTQASSSFQDSSQPAGKAEGIREPKVT 691
PK+ S + AD + P+ +SS+ P+ K + E K T
Sbjct: 733 APPKEPSVPSEQDKAPVADDKPKQPKMVKPTTDLVSSSSATTKPDIPSSKVQSQAEEKTT 792
Query: 692 GKLKQRSPKLQSS-----KKVAFLRQNAPPK-GTDTQTPAVLSPSKTQATLKPKDHHQPL 745
LK S K S +KV+ A P+ +D++ + PS K D Q
Sbjct: 793 PPLKTDSAKPSQSFPPTGEKVSPFDSKAIPRPASDSKIISHPGPSSESKGQKQVDPVQKK 852
Query: 746 GRAKGVEKQQLPEQPFEKAAFQKQNDTPKGPQP----PTVSPIRSSRPPPAKRKKSQSRG 801
K + + P+ + K + TP GP+P +P +S +P R+ S + G
Sbjct: 853 EEPKKAQTKMSPKP--DAKPMPKGSPTPPGPRPTAGQTVPTPQQSPKPQEQSRRFSLNLG 910
Query: 802 N 802
+
Sbjct: 911 S 911
Score = 36.6 bits (83), Expect = 0.096
Identities = 59/251 (23%), Positives = 88/251 (35%), Gaps = 35/251 (13%)
Query: 577 IAKFKKFS----NSIPQSQTGNSETATPTNVDLPQVIPKSENSSQPAKKA-KGAAKTKQQ 631
+ KF F + Q +T + P+ I K QP K K +
Sbjct: 170 VNKFNPFDLISDSEASQEETTKKQKVVQKEQGKPEGIIKPPLQQQPPKPIPKQQGPGRDP 229
Query: 632 LQKQQHPKKASFQKLNGISKGADSELSTVPSVTKTQASSSFQ-----DSSQPAGK-AEGI 685
LQ+ PK S Q+ I + T+T + + D+S+P K A+ +
Sbjct: 230 LQQDGTPKSISSQQPEKIKSQPPGTGKPIQGPTQTPQTDHAKLPLQRDASRPQTKQADIV 289
Query: 686 REPKVTGKL--------KQRSPKLQSSKKVAFLRQNAPPKGTDTQTPAVLSPSKTQ-ATL 736
R V L +Q +P +++ + P Q + P Q T+
Sbjct: 290 RGESVKPSLPSPSKPPIQQPTPGKPPAQQPGHEKSQPGPAKPPAQPSGLTKPLAQQPGTV 349
Query: 737 KP--------KDHHQPLGRAKGVEKQQLPEQPFEKAAFQKQNDTPKG-PQPPTVSPIRSS 787
KP K QPLG AK +Q E+P + PK QPP V +
Sbjct: 350 KPPVQPPGTTKPPAQPLGPAKPPAQQTGSEKP------SSEQPGPKALAQPPGVGKTPAQ 403
Query: 788 RPPPAKRKKSQ 798
+P PAK Q
Sbjct: 404 QPGPAKPPTQQ 414
Score = 34.7 bits (78), Expect = 0.36
Identities = 54/222 (24%), Positives = 92/222 (41%), Gaps = 36/222 (16%)
Query: 607 QVIPKSENSSQ------PAKKAKGAAKTKQQLQKQQHPKKASFQK-----LNGISKGADS 655
+ IP+ + S+ P+ ++KG K +QK++ PKKA + + KG+ +
Sbjct: 819 KAIPRPASDSKIISHPGPSSESKGQ-KQVDPVQKKEEPKKAQTKMSPKPDAKPMPKGSPT 877
Query: 656 ELSTVPSVTKT----QASSSFQDSSQ----------PAGKAEGIR-EPKVTGKLKQRSPK 700
P+ +T Q S Q+ S+ A K++ + VTGKL
Sbjct: 878 PPGPRPTAGQTVPTPQQSPKPQEQSRRFSLNLGSITDAPKSQPTTPQETVTGKLFGFGAS 937
Query: 701 L--QSSKKVAFLRQNAPPKGTDTQTPAVLSPSKTQATLKPKDHHQP--LGRAKGVEKQQL 756
+ Q+S ++ Q P + P +P+ +Q P P G+A + +
Sbjct: 938 IFSQASNLISTAGQPGPHSQSGPGAPMKQAPAPSQP---PTSQGPPKSTGQAPPAPAKSI 994
Query: 757 PEQPFEKAAFQKQNDTPKGPQPPTVSPIRS-SRPPPAKRKKS 797
P + KA ++ + PK Q PTV + +PPP K KS
Sbjct: 995 PVKKETKAPAAEKLE-PKAEQAPTVKRTETEKKPPPIKDSKS 1035
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.310 0.129 0.366
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 34,425,696
Number of Sequences: 37866
Number of extensions: 1825677
Number of successful extensions: 19220
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 167
Number of HSP's successfully gapped in prelim test: 697
Number of HSP's that attempted gapping in prelim test: 11973
Number of HSP's gapped (non-prelim): 4314
length of query: 808
length of database: 18,247,518
effective HSP length: 110
effective length of query: 698
effective length of database: 14,082,258
effective search space: 9829416084
effective search space used: 9829416084
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.