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Search of human proteins with 75677570
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|75677570 dyslexia susceptibility 1 candidate 1 isoform a
[Homo sapiens]
(420 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|75677570 dyslexia susceptibility 1 candidate 1 isoform a [Hom... 828 0.0
gi|75677567 dyslexia susceptibility 1 candidate 1 isoform b [Hom... 693 0.0
gi|75677576 dyslexia susceptibility 1 candidate 1 isoform c [Hom... 691 0.0
gi|27262638 sperm associated antigen 1 [Homo sapiens] 70 5e-12
gi|27262636 sperm associated antigen 1 [Homo sapiens] 70 5e-12
gi|24308141 small glutamine-rich tetratricopeptide repeat (TPR)-... 67 2e-11
gi|4506921 small glutamine-rich tetratricopeptide [Homo sapiens] 67 4e-11
gi|89179321 smooth muscle cell associated protein-1 isoform 3 [H... 63 4e-10
gi|29725607 smooth muscle cell associated protein-1 isoform 2 [H... 63 4e-10
gi|225735593 RNA polymerase II associated protein 3 isoform 2 [H... 62 1e-09
gi|225735591 RNA polymerase II associated protein 3 isoform 1 [H... 62 1e-09
gi|5803181 stress-induced-phosphoprotein 1 (Hsp70/Hsp90-organizi... 62 1e-09
gi|84043963 eukaryotic translation initiation factor 5B [Homo sa... 60 3e-09
gi|225735595 RNA polymerase II associated protein 3 isoform 3 [H... 59 8e-09
gi|75750484 cardiomyopathy associated 4 isoform 2 [Homo sapiens] 58 2e-08
gi|27477061 cardiomyopathy associated 4 isoform 1 [Homo sapiens] 58 2e-08
gi|56181387 STIP1 homology and U-box containing protein 1 [Homo ... 57 2e-08
gi|94538370 DnaJ (Hsp40) homolog, subfamily C, member 2 isoform ... 57 2e-08
gi|21361356 translocase of outer mitochondrial membrane 34 [Homo... 57 2e-08
gi|5453958 protein phosphatase 5, catalytic subunit [Homo sapiens] 56 7e-08
gi|41152097 DNA segment on chromosome X and Y (unique) 155 expre... 56 7e-08
gi|44680105 caldesmon 1 isoform 1 [Homo sapiens] 56 7e-08
gi|169218106 PREDICTED: hypothetical protein, partial [Homo sapi... 55 2e-07
gi|116089325 splicing factor, arginine/serine-rich 12 isoform a ... 55 2e-07
gi|21040255 splicing factor, arginine/serine-rich 12 isoform b [... 55 2e-07
gi|221219053 DnaJ (Hsp40) homolog, subfamily C, member 7 isoform... 54 3e-07
gi|18375528 UPF3 regulator of nonsense transcripts homolog B iso... 54 3e-07
gi|102467242 inner centromere protein antigens 135/155kDa isofor... 54 3e-07
gi|90669931 tetratricopeptide repeat domain 12 [Homo sapiens] 54 3e-07
gi|120953300 leucine-rich repeats and IQ motif containing 1 isof... 54 3e-07
>gi|75677570 dyslexia susceptibility 1 candidate 1 isoform a [Homo
sapiens]
Length = 420
Score = 828 bits (2138), Expect = 0.0
Identities = 420/420 (100%), Positives = 420/420 (100%)
Query: 1 MPLQVSDYSWQQTKTAVFLSLPLKGVCVRDTDVFCTENYLKVNFPPFLFEAFLYAPIDDE 60
MPLQVSDYSWQQTKTAVFLSLPLKGVCVRDTDVFCTENYLKVNFPPFLFEAFLYAPIDDE
Sbjct: 1 MPLQVSDYSWQQTKTAVFLSLPLKGVCVRDTDVFCTENYLKVNFPPFLFEAFLYAPIDDE 60
Query: 61 SSKAKIGNDTIVFTLYKKEAAMWETLSVTGVDKEMMQRIREKSILQAQERAKEATEAKAA 120
SSKAKIGNDTIVFTLYKKEAAMWETLSVTGVDKEMMQRIREKSILQAQERAKEATEAKAA
Sbjct: 61 SSKAKIGNDTIVFTLYKKEAAMWETLSVTGVDKEMMQRIREKSILQAQERAKEATEAKAA 120
Query: 121 AKREDQKYALSVMMKIEEEERKKIEDMKENERIKATKALEAWKEYQRKAEEQKKIQREEK 180
AKREDQKYALSVMMKIEEEERKKIEDMKENERIKATKALEAWKEYQRKAEEQKKIQREEK
Sbjct: 121 AKREDQKYALSVMMKIEEEERKKIEDMKENERIKATKALEAWKEYQRKAEEQKKIQREEK 180
Query: 181 LCQKEKQIKEERKKIKYKSLTRNLASRNLAPKGRNSENIFTEKLKEDSIPAPRSVGSIKI 240
LCQKEKQIKEERKKIKYKSLTRNLASRNLAPKGRNSENIFTEKLKEDSIPAPRSVGSIKI
Sbjct: 181 LCQKEKQIKEERKKIKYKSLTRNLASRNLAPKGRNSENIFTEKLKEDSIPAPRSVGSIKI 240
Query: 241 NFTPRVFPTALRESQVAEEEEWLHKQAEARRAMNTDIAELCDLKEEEKNPEWLKDKGNKL 300
NFTPRVFPTALRESQVAEEEEWLHKQAEARRAMNTDIAELCDLKEEEKNPEWLKDKGNKL
Sbjct: 241 NFTPRVFPTALRESQVAEEEEWLHKQAEARRAMNTDIAELCDLKEEEKNPEWLKDKGNKL 300
Query: 301 FATENYLAAINAYNLAIRLNNKMPLLYLNRAACHLKLKNLHKAIEDSSKALELLMPPVTD 360
FATENYLAAINAYNLAIRLNNKMPLLYLNRAACHLKLKNLHKAIEDSSKALELLMPPVTD
Sbjct: 301 FATENYLAAINAYNLAIRLNNKMPLLYLNRAACHLKLKNLHKAIEDSSKALELLMPPVTD 360
Query: 361 NANARMKAHVRRGTAFCQLELYVEGLQDYEAALKIDPSNKIVQIDAEKIRNVIQGTELKS 420
NANARMKAHVRRGTAFCQLELYVEGLQDYEAALKIDPSNKIVQIDAEKIRNVIQGTELKS
Sbjct: 361 NANARMKAHVRRGTAFCQLELYVEGLQDYEAALKIDPSNKIVQIDAEKIRNVIQGTELKS 420
>gi|75677567 dyslexia susceptibility 1 candidate 1 isoform b [Homo
sapiens]
Length = 376
Score = 693 bits (1789), Expect = 0.0
Identities = 350/354 (98%), Positives = 352/354 (99%)
Query: 1 MPLQVSDYSWQQTKTAVFLSLPLKGVCVRDTDVFCTENYLKVNFPPFLFEAFLYAPIDDE 60
MPLQVSDYSWQQTKTAVFLSLPLKGVCVRDTDVFCTENYLKVNFPPFLFEAFLYAPIDDE
Sbjct: 1 MPLQVSDYSWQQTKTAVFLSLPLKGVCVRDTDVFCTENYLKVNFPPFLFEAFLYAPIDDE 60
Query: 61 SSKAKIGNDTIVFTLYKKEAAMWETLSVTGVDKEMMQRIREKSILQAQERAKEATEAKAA 120
SSKAKIGNDTIVFTLYKKEAAMWETLSVTGVDKEMMQRIREKSILQAQERAKEATEAKAA
Sbjct: 61 SSKAKIGNDTIVFTLYKKEAAMWETLSVTGVDKEMMQRIREKSILQAQERAKEATEAKAA 120
Query: 121 AKREDQKYALSVMMKIEEEERKKIEDMKENERIKATKALEAWKEYQRKAEEQKKIQREEK 180
AKREDQKYALSVMMKIEEEERKKIEDMKENERIKATKALEAWKEYQRKAEEQKKIQREEK
Sbjct: 121 AKREDQKYALSVMMKIEEEERKKIEDMKENERIKATKALEAWKEYQRKAEEQKKIQREEK 180
Query: 181 LCQKEKQIKEERKKIKYKSLTRNLASRNLAPKGRNSENIFTEKLKEDSIPAPRSVGSIKI 240
LCQKEKQIKEERKKIKYKSLTRNLASRNLAPKGRNSENIFTEKLKEDSIPAPRSVGSIKI
Sbjct: 181 LCQKEKQIKEERKKIKYKSLTRNLASRNLAPKGRNSENIFTEKLKEDSIPAPRSVGSIKI 240
Query: 241 NFTPRVFPTALRESQVAEEEEWLHKQAEARRAMNTDIAELCDLKEEEKNPEWLKDKGNKL 300
NFTPRVFPTALRESQVAEEEEWLHKQAEARRAMNTDIAELCDLKEEEKNPEWLKDKGNKL
Sbjct: 241 NFTPRVFPTALRESQVAEEEEWLHKQAEARRAMNTDIAELCDLKEEEKNPEWLKDKGNKL 300
Query: 301 FATENYLAAINAYNLAIRLNNKMPLLYLNRAACHLKLKNLHKAIEDSSKALELL 354
FATENYLAAINAYNLAIRLNNKMPLLYLNRAACHLKLKNLHKAIEDSSKA ++
Sbjct: 301 FATENYLAAINAYNLAIRLNNKMPLLYLNRAACHLKLKNLHKAIEDSSKAYRIM 354
>gi|75677576 dyslexia susceptibility 1 candidate 1 isoform c [Homo
sapiens]
Length = 381
Score = 691 bits (1782), Expect = 0.0
Identities = 349/349 (100%), Positives = 349/349 (100%)
Query: 1 MPLQVSDYSWQQTKTAVFLSLPLKGVCVRDTDVFCTENYLKVNFPPFLFEAFLYAPIDDE 60
MPLQVSDYSWQQTKTAVFLSLPLKGVCVRDTDVFCTENYLKVNFPPFLFEAFLYAPIDDE
Sbjct: 1 MPLQVSDYSWQQTKTAVFLSLPLKGVCVRDTDVFCTENYLKVNFPPFLFEAFLYAPIDDE 60
Query: 61 SSKAKIGNDTIVFTLYKKEAAMWETLSVTGVDKEMMQRIREKSILQAQERAKEATEAKAA 120
SSKAKIGNDTIVFTLYKKEAAMWETLSVTGVDKEMMQRIREKSILQAQERAKEATEAKAA
Sbjct: 61 SSKAKIGNDTIVFTLYKKEAAMWETLSVTGVDKEMMQRIREKSILQAQERAKEATEAKAA 120
Query: 121 AKREDQKYALSVMMKIEEEERKKIEDMKENERIKATKALEAWKEYQRKAEEQKKIQREEK 180
AKREDQKYALSVMMKIEEEERKKIEDMKENERIKATKALEAWKEYQRKAEEQKKIQREEK
Sbjct: 121 AKREDQKYALSVMMKIEEEERKKIEDMKENERIKATKALEAWKEYQRKAEEQKKIQREEK 180
Query: 181 LCQKEKQIKEERKKIKYKSLTRNLASRNLAPKGRNSENIFTEKLKEDSIPAPRSVGSIKI 240
LCQKEKQIKEERKKIKYKSLTRNLASRNLAPKGRNSENIFTEKLKEDSIPAPRSVGSIKI
Sbjct: 181 LCQKEKQIKEERKKIKYKSLTRNLASRNLAPKGRNSENIFTEKLKEDSIPAPRSVGSIKI 240
Query: 241 NFTPRVFPTALRESQVAEEEEWLHKQAEARRAMNTDIAELCDLKEEEKNPEWLKDKGNKL 300
NFTPRVFPTALRESQVAEEEEWLHKQAEARRAMNTDIAELCDLKEEEKNPEWLKDKGNKL
Sbjct: 241 NFTPRVFPTALRESQVAEEEEWLHKQAEARRAMNTDIAELCDLKEEEKNPEWLKDKGNKL 300
Query: 301 FATENYLAAINAYNLAIRLNNKMPLLYLNRAACHLKLKNLHKAIEDSSK 349
FATENYLAAINAYNLAIRLNNKMPLLYLNRAACHLKLKNLHKAIEDSSK
Sbjct: 301 FATENYLAAINAYNLAIRLNNKMPLLYLNRAACHLKLKNLHKAIEDSSK 349
>gi|27262638 sperm associated antigen 1 [Homo sapiens]
Length = 926
Score = 69.7 bits (169), Expect = 5e-12
Identities = 40/128 (31%), Positives = 71/128 (55%), Gaps = 8/128 (6%)
Query: 286 EEKNPEWLKDKGNKLFATENYLAAINAYNLAIRLNNKMPLLYLNRAACHLKLKNLHKAIE 345
+EK + LK++GN+ +NY A++ Y+ +++NNK +Y NRA C+LKL +A +
Sbjct: 619 DEKTFKALKEEGNQCVNDKNYKDALSKYSECLKINNKECAIYTNRALCYLKLCQFEEAKQ 678
Query: 346 DSSKALELLMPPVTDNANARMKAHVRRGTAFCQLELYVEGLQDYEAALKIDPSNKIVQID 405
D +AL+L A+ +KA RR A L+ Y + L D + +DPS +++
Sbjct: 679 DCDQALQL--------ADGNVKAFYRRALAHKGLKNYQKSLIDLNKVILLDPSIIEAKME 730
Query: 406 AEKIRNVI 413
E++ ++
Sbjct: 731 LEEVTRLL 738
Score = 63.9 bits (154), Expect = 3e-10
Identities = 43/134 (32%), Positives = 68/134 (50%), Gaps = 16/134 (11%)
Query: 288 KNPEWLKDKGNKLFATENYLAAINAYNLAIRL--------NNKMPLLYLNRAACHLKLKN 339
+NP LK +GN+LF + + A Y+ AI L + + +LY NRAAC+LK N
Sbjct: 443 ENPAGLKSQGNELFRSGQFAEAAGKYSAAIALLEPAGSEIADDLSILYSNRAACYLKEGN 502
Query: 340 LHKAIEDSSKALELLMPPVTDNANARMKAHVRRGTAFCQLELYVEGLQDYEAALKIDPSN 399
I+D ++ALEL P + MK +RR A+ LE Y + DY+ L+ID
Sbjct: 503 CSGCIQDCNRALEL--HPFS------MKPLLRRAMAYETLEQYGKAYVDYKTVLQIDCGL 554
Query: 400 KIVQIDAEKIRNVI 413
++ ++ ++
Sbjct: 555 QLANDSVNRLSRIL 568
Score = 56.6 bits (135), Expect = 4e-08
Identities = 65/263 (24%), Positives = 111/263 (42%), Gaps = 32/263 (12%)
Query: 169 AEEQKKIQREEKLCQKEKQIKEERKKIKYKSLTRNLASRNLAPKGRNSENIFTEKLKEDS 228
AEE +KI + K E + KEE K +++ T NL P ++ + K K
Sbjct: 89 AEEWEKIDGDIKSWVSEIK-KEEDKMHFHETETFPAMKDNLPPVRGSNSCLHVGKEKYSK 147
Query: 229 IPAPRSVGSIKINFTPR---------VFPTALRESQVAEEEEWLHKQAEARRAMNTDIAE 279
P + TPR V L+ + +E+ + K ++ D A
Sbjct: 148 RPTKKK--------TPRDYAEWDKFDVEKECLKIDEDYKEKTVIDKSHLSKIETRIDTAG 199
Query: 280 LCDLKEEEKNPEWLKDKGNKLFATENYLAAINAYNLAIRLNNKMPLL--YLNRAACHLKL 337
L + KE++ K+KGN+ F + +Y A+ Y +I + +P + Y NRA +KL
Sbjct: 200 LTE-KEKDFLATREKEKGNEAFNSGDYEEAVMYYTRSI---SALPTVVAYNNRAQAEIKL 255
Query: 338 KNLHKAIEDSSKALELLMPPVTDNANARMKAHVRRGTAFCQLELYVEGLQDYEAALKIDP 397
+N + A +D K LEL +KA +RR T + E +D L ++P
Sbjct: 256 QNWNSAFQDCEKVLEL--------EPGNVKALLRRATTYKHQNKLREATEDLSKVLDVEP 307
Query: 398 SNKIVQIDAEKIRNVIQGTELKS 420
N + + ++ ++ +E S
Sbjct: 308 DNDLAKKTLSEVERDLKNSEAAS 330
>gi|27262636 sperm associated antigen 1 [Homo sapiens]
Length = 926
Score = 69.7 bits (169), Expect = 5e-12
Identities = 40/128 (31%), Positives = 71/128 (55%), Gaps = 8/128 (6%)
Query: 286 EEKNPEWLKDKGNKLFATENYLAAINAYNLAIRLNNKMPLLYLNRAACHLKLKNLHKAIE 345
+EK + LK++GN+ +NY A++ Y+ +++NNK +Y NRA C+LKL +A +
Sbjct: 619 DEKTFKALKEEGNQCVNDKNYKDALSKYSECLKINNKECAIYTNRALCYLKLCQFEEAKQ 678
Query: 346 DSSKALELLMPPVTDNANARMKAHVRRGTAFCQLELYVEGLQDYEAALKIDPSNKIVQID 405
D +AL+L A+ +KA RR A L+ Y + L D + +DPS +++
Sbjct: 679 DCDQALQL--------ADGNVKAFYRRALAHKGLKNYQKSLIDLNKVILLDPSIIEAKME 730
Query: 406 AEKIRNVI 413
E++ ++
Sbjct: 731 LEEVTRLL 738
Score = 63.9 bits (154), Expect = 3e-10
Identities = 43/134 (32%), Positives = 68/134 (50%), Gaps = 16/134 (11%)
Query: 288 KNPEWLKDKGNKLFATENYLAAINAYNLAIRL--------NNKMPLLYLNRAACHLKLKN 339
+NP LK +GN+LF + + A Y+ AI L + + +LY NRAAC+LK N
Sbjct: 443 ENPAGLKSQGNELFRSGQFAEAAGKYSAAIALLEPAGSEIADDLSILYSNRAACYLKEGN 502
Query: 340 LHKAIEDSSKALELLMPPVTDNANARMKAHVRRGTAFCQLELYVEGLQDYEAALKIDPSN 399
I+D ++ALEL P + MK +RR A+ LE Y + DY+ L+ID
Sbjct: 503 CSGCIQDCNRALEL--HPFS------MKPLLRRAMAYETLEQYGKAYVDYKTVLQIDCGL 554
Query: 400 KIVQIDAEKIRNVI 413
++ ++ ++
Sbjct: 555 QLANDSVNRLSRIL 568
Score = 56.6 bits (135), Expect = 4e-08
Identities = 65/263 (24%), Positives = 111/263 (42%), Gaps = 32/263 (12%)
Query: 169 AEEQKKIQREEKLCQKEKQIKEERKKIKYKSLTRNLASRNLAPKGRNSENIFTEKLKEDS 228
AEE +KI + K E + KEE K +++ T NL P ++ + K K
Sbjct: 89 AEEWEKIDGDIKSWVSEIK-KEEDKMHFHETETFPAMKDNLPPVRGSNSCLHVGKEKYSK 147
Query: 229 IPAPRSVGSIKINFTPR---------VFPTALRESQVAEEEEWLHKQAEARRAMNTDIAE 279
P + TPR V L+ + +E+ + K ++ D A
Sbjct: 148 RPTKKK--------TPRDYAEWDKFDVEKECLKIDEDYKEKTVIDKSHLSKIETRIDTAG 199
Query: 280 LCDLKEEEKNPEWLKDKGNKLFATENYLAAINAYNLAIRLNNKMPLL--YLNRAACHLKL 337
L + KE++ K+KGN+ F + +Y A+ Y +I + +P + Y NRA +KL
Sbjct: 200 LTE-KEKDFLATREKEKGNEAFNSGDYEEAVMYYTRSI---SALPTVVAYNNRAQAEIKL 255
Query: 338 KNLHKAIEDSSKALELLMPPVTDNANARMKAHVRRGTAFCQLELYVEGLQDYEAALKIDP 397
+N + A +D K LEL +KA +RR T + E +D L ++P
Sbjct: 256 QNWNSAFQDCEKVLEL--------EPGNVKALLRRATTYKHQNKLREATEDLSKVLDVEP 307
Query: 398 SNKIVQIDAEKIRNVIQGTELKS 420
N + + ++ ++ +E S
Sbjct: 308 DNDLAKKTLSEVERDLKNSEAAS 330
>gi|24308141 small glutamine-rich tetratricopeptide repeat
(TPR)-containing, beta [Homo sapiens]
Length = 304
Score = 67.4 bits (163), Expect = 2e-11
Identities = 45/136 (33%), Positives = 66/136 (48%), Gaps = 12/136 (8%)
Query: 285 EEEKNPEWLKDKGNKLFATENYLAAINAYNLAIRLNNKMPLLYLNRAACHLKLKNLHKAI 344
E+ + LKD+GN ENY AA++ Y AI L+ + Y NRAA KL + AI
Sbjct: 80 EDVGKADQLKDEGNNHMKEENYAAAVDCYTQAIELDPNNAVYYCNRAAAQSKLGHYTDAI 139
Query: 345 EDSSKALELLMPPVTDNANARMKAHVRRGTAFCQLELYVEGLQDYEAALKIDPSN----K 400
+D KA+ + + KA+ R G A L + E + Y+ AL +DP N
Sbjct: 140 KDCEKAIAI--------DSKYSKAYGRMGLALTALNKFEEAVTSYQKALDLDPENDSYKS 191
Query: 401 IVQIDAEKIRNVIQGT 416
++I +K+R V T
Sbjct: 192 NLKIAEQKLREVSSPT 207
>gi|4506921 small glutamine-rich tetratricopeptide [Homo sapiens]
Length = 313
Score = 66.6 bits (161), Expect = 4e-11
Identities = 41/117 (35%), Positives = 63/117 (53%), Gaps = 8/117 (6%)
Query: 284 KEEEKNPEWLKDKGNKLFATENYLAAINAYNLAIRLNNKMPLLYLNRAACHLKLKNLHKA 343
+E+ E LK +GN+ EN+ AA++ Y AI LN + + NRAA + KL N A
Sbjct: 85 EEDSAEAERLKTEGNEQMKVENFEAAVHFYGKAIELNPANAVYFCNRAAAYSKLGNYAGA 144
Query: 344 IEDSSKALELLMPPVTDNANARMKAHVRRGTAFCQLELYVEGLQDYEAALKIDPSNK 400
++D +A + + P A KA+ R G A L +VE + Y+ AL++DP N+
Sbjct: 145 VQDCERA--ICIDP------AYSKAYGRMGLALSSLNKHVEAVAYYKKALELDPDNE 193
>gi|89179321 smooth muscle cell associated protein-1 isoform 3 [Homo
sapiens]
Length = 929
Score = 63.2 bits (152), Expect = 4e-10
Identities = 42/125 (33%), Positives = 67/125 (53%), Gaps = 14/125 (11%)
Query: 291 EWLKDKGNKLFATENYLAAINAYNLAIRLN---NKMPLLYLNRAACHLKLKNLHKAIEDS 347
E L+ +GN+LF +Y A+ AY A+ L+ +L+ NRAACHLKL++ KA ++
Sbjct: 7 EQLRKEGNELFKCGDYGGALAAYTQALGLDATPQDQAVLHRNRAACHLKLEDYDKAETEA 66
Query: 348 SKALELLMPPVTDNANARMKAHVRRGTAFCQLELYVEGLQDYEAALKIDPSNKIVQIDAE 407
SKA+E +KA RR A +L + + D + + ++P NK+ Q E
Sbjct: 67 SKAIE--------KDGGDVKALYRRSQALEKLGRLDQAVLDLQRCVSLEPKNKVFQ---E 115
Query: 408 KIRNV 412
+RN+
Sbjct: 116 ALRNI 120
>gi|29725607 smooth muscle cell associated protein-1 isoform 2 [Homo
sapiens]
Length = 944
Score = 63.2 bits (152), Expect = 4e-10
Identities = 42/125 (33%), Positives = 67/125 (53%), Gaps = 14/125 (11%)
Query: 291 EWLKDKGNKLFATENYLAAINAYNLAIRLN---NKMPLLYLNRAACHLKLKNLHKAIEDS 347
E L+ +GN+LF +Y A+ AY A+ L+ +L+ NRAACHLKL++ KA ++
Sbjct: 22 EQLRKEGNELFKCGDYGGALAAYTQALGLDATPQDQAVLHRNRAACHLKLEDYDKAETEA 81
Query: 348 SKALELLMPPVTDNANARMKAHVRRGTAFCQLELYVEGLQDYEAALKIDPSNKIVQIDAE 407
SKA+E +KA RR A +L + + D + + ++P NK+ Q E
Sbjct: 82 SKAIE--------KDGGDVKALYRRSQALEKLGRLDQAVLDLQRCVSLEPKNKVFQ---E 130
Query: 408 KIRNV 412
+RN+
Sbjct: 131 ALRNI 135
>gi|225735593 RNA polymerase II associated protein 3 isoform 2 [Homo
sapiens]
Length = 631
Score = 62.0 bits (149), Expect = 1e-09
Identities = 66/265 (24%), Positives = 113/265 (42%), Gaps = 18/265 (6%)
Query: 155 ATKALEAWKEYQRKAEEQKKIQREEKLCQKEKQIKEERKKIKYKSLTRNLASRNLAP-KG 213
A KA+E + ++ AEE + R+ L EK IK++ +++ ++ + NL P +
Sbjct: 4 ANKAIELQLQVKQNAEELQDFMRD--LENWEKDIKQKDMELRRQN---GVPEENLPPIRN 58
Query: 214 RNSENIFTEKLKEDSIPAPRSVGSIKINFTPRVFPTALRESQVAEEEEWLHKQAEARRAM 273
N K KE S +I L ++ +E L K ++
Sbjct: 59 GNFRKKKKGKAKESSKKTREENTKNRIKSYDYEAWAKLDVDRILDE---LDKDDSTHESL 115
Query: 274 NTDI-AELCDLKEEEKNPEWLKDKGNKLFATENYLAAINAYNLAIRLNNKMPLLYLNRAA 332
+ + +E + + + LK+KGNK F Y AI+ Y + + P+L NRA+
Sbjct: 116 SQESESEEDGIHVDSQKALVLKEKGNKYFKQGKYDEAIDCYTKGMDADPYNPVLPTNRAS 175
Query: 333 CHLKLKNLHKAIEDSSKALELLMPPVTDNANARMKAHVRRGTAFCQLELYVEGLQDYEAA 392
+ +LK A D + A+ L + KA+ RRG A L+ E +DYE
Sbjct: 176 AYFRLKKFAVAESDCNLAVAL--------NRSYTKAYSRRGAARFALQKLEEAKKDYERV 227
Query: 393 LKIDPSNKIVQIDAEKIRNVIQGTE 417
L+++P+N + KI + E
Sbjct: 228 LELEPNNFEATNELRKISQALASKE 252
Score = 58.9 bits (141), Expect = 8e-09
Identities = 47/155 (30%), Positives = 67/155 (43%), Gaps = 22/155 (14%)
Query: 256 VAEEEEWLHKQAEARRAMNTDIAELCDLKEEEKNPEWLKDKGNKLFATENYLAAINAYNL 315
V + E KQ EA++ I+E KD+GN F Y AI Y
Sbjct: 262 VIKSTEGERKQIEAQQNKQQAISE--------------KDRGNGFFKEGKYERAIECYTR 307
Query: 316 AIRLNNKMPLLYLNRAACHLKLKNLHKAIEDSSKALELLMPPVTDNANARMKAHVRRGTA 375
I + LL NRA +LK++ +A +D ++A+ L + KA RRGTA
Sbjct: 308 GIAADGANALLPANRAMAYLKIQKYEEAEKDCTQAILL--------DGSYSKAFARRGTA 359
Query: 376 FCQLELYVEGLQDYEAALKIDPSNKIVQIDAEKIR 410
L E QD+E L ++P NK + KI+
Sbjct: 360 RTFLGKLNEAKQDFETVLLLEPGNKQAVTELSKIK 394
>gi|225735591 RNA polymerase II associated protein 3 isoform 1 [Homo
sapiens]
Length = 665
Score = 62.0 bits (149), Expect = 1e-09
Identities = 66/265 (24%), Positives = 113/265 (42%), Gaps = 18/265 (6%)
Query: 155 ATKALEAWKEYQRKAEEQKKIQREEKLCQKEKQIKEERKKIKYKSLTRNLASRNLAP-KG 213
A KA+E + ++ AEE + R+ L EK IK++ +++ ++ + NL P +
Sbjct: 4 ANKAIELQLQVKQNAEELQDFMRD--LENWEKDIKQKDMELRRQN---GVPEENLPPIRN 58
Query: 214 RNSENIFTEKLKEDSIPAPRSVGSIKINFTPRVFPTALRESQVAEEEEWLHKQAEARRAM 273
N K KE S +I L ++ +E L K ++
Sbjct: 59 GNFRKKKKGKAKESSKKTREENTKNRIKSYDYEAWAKLDVDRILDE---LDKDDSTHESL 115
Query: 274 NTDI-AELCDLKEEEKNPEWLKDKGNKLFATENYLAAINAYNLAIRLNNKMPLLYLNRAA 332
+ + +E + + + LK+KGNK F Y AI+ Y + + P+L NRA+
Sbjct: 116 SQESESEEDGIHVDSQKALVLKEKGNKYFKQGKYDEAIDCYTKGMDADPYNPVLPTNRAS 175
Query: 333 CHLKLKNLHKAIEDSSKALELLMPPVTDNANARMKAHVRRGTAFCQLELYVEGLQDYEAA 392
+ +LK A D + A+ L + KA+ RRG A L+ E +DYE
Sbjct: 176 AYFRLKKFAVAESDCNLAVAL--------NRSYTKAYSRRGAARFALQKLEEAKKDYERV 227
Query: 393 LKIDPSNKIVQIDAEKIRNVIQGTE 417
L+++P+N + KI + E
Sbjct: 228 LELEPNNFEATNELRKISQALASKE 252
Score = 58.9 bits (141), Expect = 8e-09
Identities = 47/155 (30%), Positives = 67/155 (43%), Gaps = 22/155 (14%)
Query: 256 VAEEEEWLHKQAEARRAMNTDIAELCDLKEEEKNPEWLKDKGNKLFATENYLAAINAYNL 315
V + E KQ EA++ I+E KD+GN F Y AI Y
Sbjct: 262 VIKSTEGERKQIEAQQNKQQAISE--------------KDRGNGFFKEGKYERAIECYTR 307
Query: 316 AIRLNNKMPLLYLNRAACHLKLKNLHKAIEDSSKALELLMPPVTDNANARMKAHVRRGTA 375
I + LL NRA +LK++ +A +D ++A+ L + KA RRGTA
Sbjct: 308 GIAADGANALLPANRAMAYLKIQKYEEAEKDCTQAILL--------DGSYSKAFARRGTA 359
Query: 376 FCQLELYVEGLQDYEAALKIDPSNKIVQIDAEKIR 410
L E QD+E L ++P NK + KI+
Sbjct: 360 RTFLGKLNEAKQDFETVLLLEPGNKQAVTELSKIK 394
>gi|5803181 stress-induced-phosphoprotein 1 (Hsp70/Hsp90-organizing
protein) [Homo sapiens]
Length = 543
Score = 62.0 bits (149), Expect = 1e-09
Identities = 61/221 (27%), Positives = 102/221 (46%), Gaps = 38/221 (17%)
Query: 180 KLCQKEKQIKEERKKIKYKSLTRNLASRNLAPKGRNSENIFTEKLKEDSIPAPRSVGSIK 239
+LC+K ++ E ++ Y+ + + A R + F E+ +D+I S+
Sbjct: 280 ELCEKAIEVGRENRE-DYRQIAKAYA--------RIGNSYFKEEKYKDAIHFYNK--SLA 328
Query: 240 INFTPRVFPTALRESQVAEEEEWLHKQAEARRAMNTDIAELCDLKEEEKNPEWLKDKGNK 299
+ TP V L++ Q AE+ + K+ E +N D+A EEKN KGN+
Sbjct: 329 EHRTPDV----LKKCQQAEK---ILKEQERLAYINPDLAL------EEKN------KGNE 369
Query: 300 LFATENYLAAINAYNLAIRLNNKMPLLYLNRAACHLKLKNLHKAIEDSSKALELLMPPVT 359
F +Y A+ Y AI+ N K LY NRAAC+ KL A++D + ++L
Sbjct: 370 CFQKGDYPQAMKHYTEAIKRNPKDAKLYSNRAACYTKLLEFQLALKDCEECIQL------ 423
Query: 360 DNANARMKAHVRRGTAFCQLELYVEGLQDYEAALKIDPSNK 400
+K + R+ A ++ Y + + Y+ AL +D S K
Sbjct: 424 --EPTFIKGYTRKAAALEAMKDYTKAMDVYQKALDLDSSCK 462
Score = 49.7 bits (117), Expect = 5e-06
Identities = 34/107 (31%), Positives = 52/107 (48%), Gaps = 8/107 (7%)
Query: 293 LKDKGNKLFATENYLAAINAYNLAIRLNNKMPLLYLNRAACHLKLKNLHKAIEDSSKALE 352
LK+KGNK + N A+ Y+ AI+L+ +LY NR+A + K + KA ED K ++
Sbjct: 7 LKEKGNKALSVGNIDDALQCYSEAIKLDPHNHVLYSNRSAAYAKKGDYQKAYEDGCKTVD 66
Query: 353 LLMPPVTDNANARMKAHVRRGTAFCQLELYVEGLQDYEAALKIDPSN 399
L K + R+ A L + E + YE LK + +N
Sbjct: 67 L--------KPDWGKGYSRKAAALEFLNRFEEAKRTYEEGLKHEANN 105
Score = 38.1 bits (87), Expect = 0.015
Identities = 78/345 (22%), Positives = 132/345 (38%), Gaps = 65/345 (18%)
Query: 84 ETLSVTGVDKEMMQRIREKSILQAQERAKEATEAKAAAKREDQKYALSVMMKIEEEERKK 143
+ LSV +D + +Q E L + + A AK+ D + A E+ K
Sbjct: 13 KALSVGNID-DALQCYSEAIKLDPHNHVLYSNRSAAYAKKGDYQKAY--------EDGCK 63
Query: 144 IEDMKEN------ERIKATKALEAWKEYQRKAEEQKKI-----QREEKLCQKEKQIKEER 192
D+K + + A + L ++E +R EE K Q +E L E ++ E +
Sbjct: 64 TVDLKPDWGKGYSRKAAALEFLNRFEEAKRTYEEGLKHEANNPQLKEGLQNMEARLAERK 123
Query: 193 -----------KKIKYKSLTRNLAS----RNLAPKGRNSENIFTEKLKEDSIPAPRSV-- 235
+K++ TR L S R L + RN + KL++ I SV
Sbjct: 124 FMNPFNMPNLYQKLESDPRTRTLLSDPTYRELIEQLRNKPSDLGTKLQDPRIMTTLSVLL 183
Query: 236 ----GSIKIN---FTPRVFPTALRESQVAEEEEWLHKQAEARRAMNTDIAELCDLKEEEK 288
GS+ TP P +E++ EE DL E +K
Sbjct: 184 GVDLGSMDEEEEIATPPPPPPPKKETKPEPMEE--------------------DLPENKK 223
Query: 289 NPEWLKDKGNKLFATENYLAAINAYNLAIRLNNKMPLLYLNRAACHLKLKNLHKAIEDSS 348
K+ GN + +++ A+ Y+ A L+ N+AA + + + +K E
Sbjct: 224 QALKEKELGNDAYKKKDFDTALKHYDKAKELDPTNMTYITNQAAVYFEKGDYNKCRELCE 283
Query: 349 KALELLMPPVTDNANARMKAHVRRGTAFCQLELYVEGLQDYEAAL 393
KA+E+ D KA+ R G ++ + E Y + + Y +L
Sbjct: 284 KAIEVGRENREDYRQI-AKAYARIGNSYFKEEKYKDAIHFYNKSL 327
>gi|84043963 eukaryotic translation initiation factor 5B [Homo
sapiens]
Length = 1220
Score = 60.5 bits (145), Expect = 3e-09
Identities = 70/262 (26%), Positives = 117/262 (44%), Gaps = 34/262 (12%)
Query: 58 DDESSKAKIGNDTIVFTLYKKEAAMWETLSVTGVDKEMMQRIREKSILQAQERAKEATEA 117
++E+ K+K+ DT V +++A ET + D E ++ ++K + ++ KE +
Sbjct: 277 EEETVKSKVTVDTGVIPASEEKA---ETPTAAEDDNEGDKKKKDKKKKKGEKEEKEKEKK 333
Query: 118 KAAAKREDQKYALSVMMKIEEEERKKIEDMKENERIKATKALEAWKEYQRKAEEQKKIQR 177
K +K + ++ EEEER+K E E ERIK + LEA +RK EE+ + ++
Sbjct: 334 KGPSKATVKAMQEALAKLKEEEERQKRE---EEERIKRLEELEA----KRKEEERLEQEK 386
Query: 178 EEKLCQKEKQIKEERK---KIKYKSLTRNLASRNLAPKGRNSENIFTEKLKEDSIPAPRS 234
E+ QKEK+ KE K K+ KS A K ++ + E +DS+P R
Sbjct: 387 RERKKQKEKERKERLKKEGKLLTKSQREARARAEATLKLLQAQGV--EVPSKDSLPKKRP 444
Query: 235 VGSIKINFTPRVFPTALRESQVAE----------------EEEWLHKQAEARRAMNTDIA 278
+ K + P L +V+E E+E E +T+ A
Sbjct: 445 IYEDK---KRKKIPQQLESKEVSESMELCAAVEVMEQGVPEKEETPPPVEPEEEEDTEDA 501
Query: 279 ELCDLKEEEKNPEWLKDKGNKL 300
L D + + E K +GNK+
Sbjct: 502 GLDDWEAMASDEETEKVEGNKV 523
Score = 29.6 bits (65), Expect = 5.4
Identities = 20/67 (29%), Positives = 33/67 (49%), Gaps = 9/67 (13%)
Query: 107 AQERAKEATEAKAAAKREDQKYALSVMMKIEEEERKKIEDMKENERIKATKALEA-WKEY 165
A + K + KA K ++K +EE+ K+ +KE E ++ K ++ KE
Sbjct: 221 ASFKIKTVAQKKAEKKERERKK--------RDEEKAKLRKLKEKEELETGKKDQSKQKES 272
Query: 166 QRKAEEQ 172
QRK EE+
Sbjct: 273 QRKFEEE 279
Score = 29.3 bits (64), Expect = 7.0
Identities = 34/162 (20%), Positives = 67/162 (41%), Gaps = 27/162 (16%)
Query: 148 KENERIKATKALEAWKE-----YQRKAEEQKKIQREEKLCQKEKQIKEERKKIKYKSLTR 202
K+N++ K +E+ E ++ K QKK +++E+ +K + K + +K+K K
Sbjct: 201 KKNQKNKPGPNIESGNEDDDASFKIKTVAQKKAEKKERERKKRDEEKAKLRKLKEKE--- 257
Query: 203 NLASRNLAPKGRNSENIFTEKLKEDSIPAPRSV--GSIKINFTPRVFPTALRESQVA--- 257
K ++ + K +E+++ + +V G I + PTA +
Sbjct: 258 ---ELETGKKDQSKQKESQRKFEEETVKSKVTVDTGVIPASEEKAETPTAAEDDNEGDKK 314
Query: 258 -----------EEEEWLHKQAEARRAMNTDIAELCDLKEEEK 288
EE+E K+ ++ + L LKEEE+
Sbjct: 315 KKDKKKKKGEKEEKEKEKKKGPSKATVKAMQEALAKLKEEEE 356
Score = 29.3 bits (64), Expect = 7.0
Identities = 31/119 (26%), Positives = 50/119 (42%), Gaps = 20/119 (16%)
Query: 122 KREDQKYALSVMMKIEEEERKKIEDMKENERIKATKALEAWKEYQRKAEEQKKIQRE--- 178
K E K + V EEEE ++ E+ +E+E + + E E EE +K+ E
Sbjct: 517 KVEGNKVHIEVKENPEEEEEEE-EEEEEDEESEEEEEEEGESEGSEGDEEDEKVSDEKDS 575
Query: 179 ----EKLCQKEKQIKEE--------RKKIKYKSLTRNLASRNLAPKGRNSENIFTEKLK 225
+K KE E +++ Y R + R L +S+N+ TEKL+
Sbjct: 576 GKTLDKKPSKEMSSDSEYDSDDDRTKEERAYDKAKRRIEKRRL----EHSKNVNTEKLR 630
>gi|225735595 RNA polymerase II associated protein 3 isoform 3 [Homo
sapiens]
Length = 506
Score = 58.9 bits (141), Expect = 8e-09
Identities = 47/155 (30%), Positives = 67/155 (43%), Gaps = 22/155 (14%)
Query: 256 VAEEEEWLHKQAEARRAMNTDIAELCDLKEEEKNPEWLKDKGNKLFATENYLAAINAYNL 315
V + E KQ EA++ I+E KD+GN F Y AI Y
Sbjct: 103 VIKSTEGERKQIEAQQNKQQAISE--------------KDRGNGFFKEGKYERAIECYTR 148
Query: 316 AIRLNNKMPLLYLNRAACHLKLKNLHKAIEDSSKALELLMPPVTDNANARMKAHVRRGTA 375
I + LL NRA +LK++ +A +D ++A+ L + KA RRGTA
Sbjct: 149 GIAADGANALLPANRAMAYLKIQKYEEAEKDCTQAILL--------DGSYSKAFARRGTA 200
Query: 376 FCQLELYVEGLQDYEAALKIDPSNKIVQIDAEKIR 410
L E QD+E L ++P NK + KI+
Sbjct: 201 RTFLGKLNEAKQDFETVLLLEPGNKQAVTELSKIK 235
Score = 41.2 bits (95), Expect = 0.002
Identities = 28/94 (29%), Positives = 44/94 (46%), Gaps = 8/94 (8%)
Query: 324 PLLYLNRAACHLKLKNLHKAIEDSSKALELLMPPVTDNANARMKAHVRRGTAFCQLELYV 383
P+L NRA+ + +LK A D + A+ L + KA+ RRG A L+
Sbjct: 8 PVLPTNRASAYFRLKKFAVAESDCNLAVAL--------NRSYTKAYSRRGAARFALQKLE 59
Query: 384 EGLQDYEAALKIDPSNKIVQIDAEKIRNVIQGTE 417
E +DYE L+++P+N + KI + E
Sbjct: 60 EAKKDYERVLELEPNNFEATNELRKISQALASKE 93
Score = 34.3 bits (77), Expect = 0.22
Identities = 19/65 (29%), Positives = 30/65 (46%)
Query: 289 NPEWLKDKGNKLFATENYLAAINAYNLAIRLNNKMPLLYLNRAACHLKLKNLHKAIEDSS 348
NP ++ + F + + A + NLA+ LN Y R A L+ L +A +D
Sbjct: 7 NPVLPTNRASAYFRLKKFAVAESDCNLAVALNRSYTKAYSRRGAARFALQKLEEAKKDYE 66
Query: 349 KALEL 353
+ LEL
Sbjct: 67 RVLEL 71
>gi|75750484 cardiomyopathy associated 4 isoform 2 [Homo sapiens]
Length = 929
Score = 57.8 bits (138), Expect = 2e-08
Identities = 38/125 (30%), Positives = 66/125 (52%), Gaps = 11/125 (8%)
Query: 293 LKDKGNKLFATENYLAAINAYNLAIRLNNKMPL---LYLNRAACHLKLKNLHKAIEDSSK 349
LK++GN+ F ++Y AA N+Y+ A++L L LY NRAAC LK ++ +A D+S+
Sbjct: 9 LKEEGNRHFQLQDYKAATNSYSQALKLTKDKALLATLYRNRAACGLKTESYVQAASDASR 68
Query: 350 ALELLMPPVTDNANARMKAHVRRGTAFCQLELYVEGLQDYEAALKIDPSNKIVQIDAEKI 409
A+++ ++ +KA RR A L + +D + ++P N+ Q ++
Sbjct: 69 AIDI--------NSSDIKALYRRCQALEHLGKLDQAFKDVQRCATLEPRNQNFQEMLRRL 120
Query: 410 RNVIQ 414
IQ
Sbjct: 121 NTSIQ 125
>gi|27477061 cardiomyopathy associated 4 isoform 1 [Homo sapiens]
Length = 931
Score = 57.8 bits (138), Expect = 2e-08
Identities = 38/125 (30%), Positives = 66/125 (52%), Gaps = 11/125 (8%)
Query: 293 LKDKGNKLFATENYLAAINAYNLAIRLNNKMPL---LYLNRAACHLKLKNLHKAIEDSSK 349
LK++GN+ F ++Y AA N+Y+ A++L L LY NRAAC LK ++ +A D+S+
Sbjct: 9 LKEEGNRHFQLQDYKAATNSYSQALKLTKDKALLATLYRNRAACGLKTESYVQAASDASR 68
Query: 350 ALELLMPPVTDNANARMKAHVRRGTAFCQLELYVEGLQDYEAALKIDPSNKIVQIDAEKI 409
A+++ ++ +KA RR A L + +D + ++P N+ Q ++
Sbjct: 69 AIDI--------NSSDIKALYRRCQALEHLGKLDQAFKDVQRCATLEPRNQNFQEMLRRL 120
Query: 410 RNVIQ 414
IQ
Sbjct: 121 NTSIQ 125
>gi|56181387 STIP1 homology and U-box containing protein 1 [Homo
sapiens]
Length = 303
Score = 57.4 bits (137), Expect = 2e-08
Identities = 36/117 (30%), Positives = 58/117 (49%), Gaps = 10/117 (8%)
Query: 287 EKNP--EWLKDKGNKLFATENYLAAINAYNLAIRLNNKMPLLYLNRAACHLKLKNLHKAI 344
EK+P + LK++GN+LF Y A Y AI N + + Y NRA C+LK++ +A+
Sbjct: 21 EKSPSAQELKEQGNRLFVGRKYPEAAACYGRAITRNPLVAVYYTNRALCYLKMQQHEQAL 80
Query: 345 EDSSKALELLMPPVTDNANARMKAHVRRGTAFCQLELYVEGLQDYEAALKIDPSNKI 401
D +ALEL +KAH G ++E Y E + + + A + ++
Sbjct: 81 ADCRRALEL--------DGQSVKAHFFLGQCQLEMESYDEAIANLQRAYSLAKEQRL 129
>gi|94538370 DnaJ (Hsp40) homolog, subfamily C, member 2 isoform 1
[Homo sapiens]
Length = 621
Score = 57.4 bits (137), Expect = 2e-08
Identities = 94/400 (23%), Positives = 162/400 (40%), Gaps = 54/400 (13%)
Query: 6 SDYSWQQTKTAVFLSLPLKGVCVRDTD-VFCTENYLKVNFPPFLFEAFLYAPIDDESSK- 63
+DY TK LS P+K D F K FE F P+ + +S+
Sbjct: 135 NDYFTCITKAYEMLSDPVKRRAFNSVDPTFDNSVPSKSEAKDNFFEVF--TPVFERNSRW 192
Query: 64 ------AKIGN------DTIVFTLYKKEAAMWETLS-VTGVDKEMMQRIREKSILQAQER 110
K+G+ D +F + W S + +KE + E+ ++ Q R
Sbjct: 193 SNKKNVPKLGDMNSSFEDVDIFYSFWYNFDSWREFSYLDEEEKEKAECRDERRWIEKQNR 252
Query: 111 AKEATEAKAAAKR----EDQKYALSVMMKIEEEERKKIEDMKENERIKATKALEAWKEYQ 166
A A K R D Y+ +K +EE K ++ ++ + +A + + KE Q
Sbjct: 253 ATRAQRKKEEMNRIRTLVDNAYSCDPRIKKFKEEEKAKKEAEKKAKAEAKRKEQEAKEKQ 312
Query: 167 RKAE----------EQKKIQREEKLCQKEKQI-----KEERKKIKYKSLTRNLASRNLAP 211
R+AE E+++++++ L +KEK I K+ER+K++ T N S N A
Sbjct: 313 RQAELEAARLAKEKEEEEVRQQALLAKKEKDIQKKAIKKERQKLRNSCKTWNHFSDNEAE 372
Query: 212 KGRNSENIFTEKLKED-SIPAPRSVGSIKINFTPRVFPTALRESQVAEEEEWLHKQAEAR 270
+ + E + EKL + + + + + + T V AL E Q+ E E + K+ E
Sbjct: 373 RVKMMEEV--EKLCDRLELASLQCLNETLTSCTKEVGKAAL-EKQIEEINEQIRKEKEEA 429
Query: 271 RAMNTDIAELCDLKEEEKNPEWLK---DKGNKLFATENYLAAINAYNLAIRLNNKMPLLY 327
A +++ KN E G+K ++ ++ I A NL N +
Sbjct: 430 EAR---------MRQASKNTEKSTGGGGNGSKNWSEDDLQLLIKAVNLFPAGTNSRWEVI 480
Query: 328 LNRAACHLK--LKNLHKAIEDSSKALELLMPPVTDNANAR 365
N H +K K + +K+L+ L P D+ N +
Sbjct: 481 ANYMNIHSSSGVKRTAKDVIGKAKSLQKLDPHQKDDINKK 520
>gi|21361356 translocase of outer mitochondrial membrane 34 [Homo
sapiens]
Length = 309
Score = 57.4 bits (137), Expect = 2e-08
Identities = 40/122 (32%), Positives = 63/122 (51%), Gaps = 12/122 (9%)
Query: 293 LKDKGNKLFATENYLAAINAYNLAIRLNNKMPLLYLNRAACHLKLKNLHKAIEDSSKALE 352
LK++GN+L N+ AI Y+ ++ +N Y NRA C+L LK +A++D ++AL+
Sbjct: 196 LKEEGNELVKKGNHKKAIEKYSESLLCSNLESATYSNRALCYLVLKQYTEAVKDCTEALK 255
Query: 353 LLMPPVTDNANARMKAHVRRGTAFCQLELYVEGLQDYEAALKIDPSNKIVQIDAEKIRNV 412
L D N +KA RR A L+ Y D L+I+P N A+K+R
Sbjct: 256 L------DGKN--VKAFYRRAQAHKALKDYKSSFADISNLLQIEPRNG----PAQKLRQE 303
Query: 413 IQ 414
++
Sbjct: 304 VK 305
Score = 51.6 bits (122), Expect = 1e-06
Identities = 39/114 (34%), Positives = 55/114 (48%), Gaps = 16/114 (14%)
Query: 291 EWLKDKGNKLFATENYLAAINAYNLAIRL--------NNKMPLLYLNRAACHLKLKNLHK 342
E L+ GN+ F Y A Y A+R+ + +LY NRAACHLK N
Sbjct: 10 EELRAAGNESFRNGQYAEASALYGRALRVLQAQGSSDPEEESVLYSNRAACHLKDGNCRD 69
Query: 343 AIEDSSKALELLMPPVTDNANARMKAHVRRGTAFCQLELYVEGLQDYEAALKID 396
I+D + AL L+ P + +K +RR +A+ LE Y DY+ L+ID
Sbjct: 70 CIKDCTSALALV--PFS------IKPLLRRASAYEALEKYPMAYVDYKTVLQID 115
>gi|5453958 protein phosphatase 5, catalytic subunit [Homo sapiens]
Length = 499
Score = 55.8 bits (133), Expect = 7e-08
Identities = 34/127 (26%), Positives = 63/127 (49%), Gaps = 8/127 (6%)
Query: 288 KNPEWLKDKGNKLFATENYLAAINAYNLAIRLNNKMPLLYLNRAACHLKLKNLHKAIEDS 347
K E LK + N F ++Y AI Y+ AI LN + Y NR+ +L+ + A+ D+
Sbjct: 26 KRAEELKTQANDYFKAKDYENAIKFYSQAIELNPSNAIYYGNRSLAYLRTECYGYALGDA 85
Query: 348 SKALELLMPPVTDNANARMKAHVRRGTAFCQLELYVEGLQDYEAALKIDPSNKIVQIDAE 407
++A+EL +K + RR + L + L+DYE +K+ P +K ++ +
Sbjct: 86 TRAIEL--------DKKYIKGYYRRAASNMALGKFRAALRDYETVVKVKPHDKDAKMKYQ 137
Query: 408 KIRNVIQ 414
+ +++
Sbjct: 138 ECNKIVK 144
>gi|41152097 DNA segment on chromosome X and Y (unique) 155
expressed sequence isoform 1 [Homo sapiens]
Length = 695
Score = 55.8 bits (133), Expect = 7e-08
Identities = 50/218 (22%), Positives = 105/218 (48%), Gaps = 15/218 (6%)
Query: 93 KEMMQRIREKSILQAQERAKEATEAKAAAKR-----EDQKYALSVMMKIEEEERKKIEDM 147
+E M I+ S L+ + + + KA A + K+ +K + ER+K++++
Sbjct: 222 REYMGFIQAMSALRGMKLMYKGEDGKAVACNIKVSFDSTKHLSDASIKKRQLERQKLQEL 281
Query: 148 KENERIKATKALEAWKEYQRKAEEQKKIQREEKLCQKEKQIKEERKKIKYKSLTRNLASR 207
++ + + EA + + + +QK+++ E+ ++E+++++ +K + + L RN +
Sbjct: 282 EQQREEQKRREKEAEERQRAEERKQKELEELERERKREEKLRKREQKQRDRELRRN--QK 339
Query: 208 NLAPKGRNSENIFTEKLKEDS---IPAPRSVGSIKI--NFTPRVFPTALRESQVAEEEEW 262
L + EK+K + + A R++ SI++ R LRE + EE+
Sbjct: 340 KLEKLQAEEQKQLQEKIKLEERKLLLAQRNLQSIRLIAELLSRAKAVKLREQEQKEEKLR 399
Query: 263 LHKQAEARRAMNTDIAELCDLKEEEKNPEWLKDKGNKL 300
L +Q E RR AEL ++EE++ L+ K +L
Sbjct: 400 LQQQEERRRLQE---AELRRVEEEKERALGLQRKEREL 434
Score = 33.9 bits (76), Expect = 0.28
Identities = 31/145 (21%), Positives = 70/145 (48%), Gaps = 12/145 (8%)
Query: 92 DKEMMQRIREKSILQAQERAKEATEAKAAAKREDQKYALSV------MMKIEEEERKKIE 145
+ E QR E+ + +E +E + KRE ++ + + K++ EE+K+++
Sbjct: 294 EAEERQRAEERKQKELEELERERKREEKLRKREQKQRDRELRRNQKKLEKLQAEEQKQLQ 353
Query: 146 D---MKENERIKATKALEAWK---EYQRKAEEQKKIQREEKLCQKEKQIKEERKKIKYKS 199
+ ++E + + A + L++ + E +A+ K ++E+K + Q +EER++++
Sbjct: 354 EKIKLEERKLLLAQRNLQSIRLIAELLSRAKAVKLREQEQKEEKLRLQQQEERRRLQEAE 413
Query: 200 LTRNLASRNLAPKGRNSENIFTEKL 224
L R + A + E E+L
Sbjct: 414 LRRVEEEKERALGLQRKERELRERL 438
>gi|44680105 caldesmon 1 isoform 1 [Homo sapiens]
Length = 793
Score = 55.8 bits (133), Expect = 7e-08
Identities = 42/131 (32%), Positives = 72/131 (54%), Gaps = 8/131 (6%)
Query: 78 KEAAMWETLSVTGVDKEMMQRIREKSILQAQERAKEATEAKAAAKREDQKYALSVMMKIE 137
KE A E + ++E ++ ++K I A ERA+ E KAAA+ +++ A ++
Sbjct: 262 KERAEAERARLEAEERERIKAEQDKKI--ADERARIEAEEKAAAQERERREA-EERERMR 318
Query: 138 EEERKKIED---MKENERIKATKALEAWKEYQRKAEEQKKIQREEKLCQKEKQ--IKEER 192
EEE++ E+ +KE E+ A + +E +R AEE+++I+ EEK +E+Q EE
Sbjct: 319 EEEKRAAEERQRIKEEEKRAAEERQRIKEEEKRAAEERQRIKEEEKRAAEERQRARAEEE 378
Query: 193 KKIKYKSLTRN 203
+K K + RN
Sbjct: 379 EKAKVEEQKRN 389
Score = 48.5 bits (114), Expect = 1e-05
Identities = 40/146 (27%), Positives = 74/146 (50%), Gaps = 12/146 (8%)
Query: 58 DDESSKAKIGNDTIVFTLYKKEAAMWETLSVTGVDKEMMQRIREKSILQAQERAKEATEA 117
+++ + IG + + + +K E V + + K Q +ER + + E
Sbjct: 195 EEKPKRGSIGENQVEVMVEEKTTESQEETVVMSLKNGQISSEEPK---QEEEREQGSDEI 251
Query: 118 KAAAK--REDQKYALSVMMKIEEEERKKI---EDMK---ENERIKATKALEAWKEYQRKA 169
K ED++ A + ++E EER++I +D K E RI+A + A + +R+A
Sbjct: 252 SHHEKMEEEDKERAEAERARLEAEERERIKAEQDKKIADERARIEAEEKAAAQERERREA 311
Query: 170 EEQKKIQREEKLCQKEKQ-IKEERKK 194
EE+++++ EEK +E+Q IKEE K+
Sbjct: 312 EERERMREEEKRAAEERQRIKEEEKR 337
Score = 45.1 bits (105), Expect = 1e-04
Identities = 81/402 (20%), Positives = 156/402 (38%), Gaps = 98/402 (24%)
Query: 94 EMMQRIREKSILQAQERAKEATEAKAAAK-----REDQKYALSVMMKI--EEEERKKIED 146
E QRI+E+ A+ER + E K AA+ +E++K A + EEEE+ K+E+
Sbjct: 326 EERQRIKEEEKRAAEERQRIKEEEKRAAEERQRIKEEEKRAAEERQRARAEEEEKAKVEE 385
Query: 147 MKENERI---------------KATKALEAWKEYQRKAEEQK---------------KIQ 176
K N+++ K + +E ++KA+E K K+Q
Sbjct: 386 QKRNKQLEEKKHAMQETKIKGEKVEQKIEGKWVNEKKAQEDKLQTAVLKKQGEEKGTKVQ 445
Query: 177 ------REEKLCQKEKQIKEERKK------------IKYKSLTRNLASRN---LAPKGRN 215
+E+K K+++IK+E+ K + K + S+N + K ++
Sbjct: 446 AKREKLQEDKPTFKKEEIKDEKIKKDKEPKEEVKSFMDRKKGFTEVKSQNGEFMTHKLKH 505
Query: 216 SENIFTEKLKEDSIPAPRSVGSIKINFTPRVFPTALRESQVAEEE--------------- 260
+EN F+ S+ + G+ ++ R+ R + EE
Sbjct: 506 TENTFSRPGGRASVDTKEAEGAPQVEAGKRLEELRRRRGETESEEFEKLKQKQQEAALEL 565
Query: 261 EWLHKQAEARRAMNTDIAELCDLKEEEKNPEWLKDKGNKLFATENYLAAINAYNLAIRL- 319
E L K+ E RR + + E K+EE + + +++ + E A ++
Sbjct: 566 EELKKKREERRKVLEE--EEQRRKQEEADRKLREEEEKRRLKEEIERRRAEAAEKRQKMP 623
Query: 320 -----NNKMPLLYLNRAACHLKLKN----LHKAIEDSSKALELLMPPVTDNANARMKAHV 370
++K P LK++ L+K+++ SS + ++R
Sbjct: 624 EDGLSDDKKPFKCFTPKGSSLKIEERAEFLNKSVQKSSGVKSTHQAAIVSKIDSR----- 678
Query: 371 RRGTAFCQLELYVEGLQDYEAALKIDPSNKIVQIDAEKIRNV 412
LE Y ++ ++A P+ + + AE +RN+
Sbjct: 679 --------LEQYTSAIEGTKSAKPTKPAASDLPVPAEGVRNI 712
Score = 44.7 bits (104), Expect = 2e-04
Identities = 38/140 (27%), Positives = 70/140 (50%), Gaps = 19/140 (13%)
Query: 92 DKEMMQRIREKSILQAQERAKEATEAKAAAK-----REDQKYALSVMMKIEEEERKKIED 146
+ E +R+RE+ A+ER + E K AA+ +E++K A +I+EEE++ E
Sbjct: 310 EAEERERMREEEKRAAEERQRIKEEEKRAAEERQRIKEEEKRAAEERQRIKEEEKRAAE- 368
Query: 147 MKENERIKATKALEAWKEYQRKAEEQKKIQREEKLCQKEKQIKEERKKIKYKSLTRNLAS 206
E +R +A +E + K EEQK+ ++ E EK+ + KIK + + + +
Sbjct: 369 --ERQRARAE------EEEKAKVEEQKRNKQLE-----EKKHAMQETKIKGEKVEQKIEG 415
Query: 207 RNLAPKGRNSENIFTEKLKE 226
+ + K + + T LK+
Sbjct: 416 KWVNEKKAQEDKLQTAVLKK 435
Score = 41.6 bits (96), Expect = 0.001
Identities = 49/234 (20%), Positives = 100/234 (42%), Gaps = 26/234 (11%)
Query: 78 KEAAMWETLSVTGVDKEMMQRIREKSILQAQERAKEATEAKAAAKREDQKYALSVMMKIE 137
K ++ E V+++ + E ++ + + E K +RE +S K+E
Sbjct: 199 KRGSIGENQVEVMVEEKTTESQEETVVMSLKNGQISSEEPKQEEEREQGSDEISHHEKME 258
Query: 138 EEERKKIE------DMKENERIKATKALEAWKEYQR-------KAEEQKKIQRE--EKLC 182
EE++++ E + +E ERIKA + + E R A+E+++ + E E++
Sbjct: 259 EEDKERAEAERARLEAEERERIKAEQDKKIADERARIEAEEKAAAQERERREAEERERMR 318
Query: 183 QKEKQIKEERKKIKYKSLTRNLASRNLAPKGRNSENIFTEKLKEDSIPAPRSVGSIKINF 242
++EK+ EER++IK + R R + +++KE+ A
Sbjct: 319 EEEKRAAEERQRIKEEE-KRAAEERQRIKEEEKRAAEERQRIKEEEKRAAEE-------- 369
Query: 243 TPRVFPTALRESQVAEEEEWLHKQAEARRAMNTDIAELCDLKEEEKNPEWLKDK 296
R A E + EE+ +KQ E ++ + + E++ +W+ +K
Sbjct: 370 --RQRARAEEEEKAKVEEQKRNKQLEEKKHAMQETKIKGEKVEQKIEGKWVNEK 421
Score = 35.4 bits (80), Expect = 0.098
Identities = 42/181 (23%), Positives = 83/181 (45%), Gaps = 25/181 (13%)
Query: 100 REKSILQAQERAKE----ATEAKAA--AKREDQKYALSVMMKIEE--EERKKIEDMKENE 151
R+K + +A ER KE T+A + ++R A + + EE E R++ +++E E
Sbjct: 107 RQKRLQEALERQKEFDPTITDASLSLPSRRMQNDTAENETTEKEEKSESRQERYEIEETE 166
Query: 152 RIKATKALEAWKEYQRKAEEQKKIQREEKLCQKEKQIKEERKKIKYKSLTRNLASRNLAP 211
+ + W++ + +E K+ + EE+ K I E + ++ + T +
Sbjct: 167 TVTKSYQKNDWRDAEENKKEDKEKEEEEEEKPKRGSIGENQVEVMVEEKTTESQEETVVM 226
Query: 212 KGRNSENIFTEKLKEDSIPAPRSVGSIKINFTPRVFPTALRESQVAEEEEWLHKQAEARR 271
+N + I +E+ K++ R GS +I+ ++ EEE+ ++AEA R
Sbjct: 227 SLKNGQ-ISSEEPKQEE---EREQGSDEISHHEKM-----------EEED--KERAEAER 269
Query: 272 A 272
A
Sbjct: 270 A 270
Score = 32.0 bits (71), Expect = 1.1
Identities = 33/125 (26%), Positives = 58/125 (46%), Gaps = 24/125 (19%)
Query: 92 DKEMMQRIREKSILQAQERAKEATEAKAAAKREDQKYALSVMMKIEEEERKKIE--DMKE 149
+ E +++++K QE A E E K KRE+++ L EEE+R+K E D K
Sbjct: 547 ESEEFEKLKQKQ----QEAALELEELK--KKREERRKVLE-----EEEQRRKQEEADRKL 595
Query: 150 NERIKATKALEAWKEYQRKAEEQKKIQREEKLCQKEKQIK-----------EERKKIKYK 198
E + + E + + +A E+++ E+ L +K K EER + K
Sbjct: 596 REEEEKRRLKEEIERRRAEAAEKRQKMPEDGLSDDKKPFKCFTPKGSSLKIEERAEFLNK 655
Query: 199 SLTRN 203
S+ ++
Sbjct: 656 SVQKS 660
>gi|169218106 PREDICTED: hypothetical protein, partial [Homo
sapiens]
Length = 436
Score = 54.7 bits (130), Expect = 2e-07
Identities = 47/223 (21%), Positives = 101/223 (45%), Gaps = 22/223 (9%)
Query: 77 KKEAAMWETLSVTGVDKEMMQRIREKSILQAQERAKEATEAKAAAKREDQKYALSV---- 132
++E M E G +E MQ+ +E+ + + +E+ ++ E + + QK V
Sbjct: 196 EQEGQMGEQEEQMGEQEEQMQK-QEEQMGEQEEQMRKQEEQMGEQEEQVQKQEEQVQKQE 254
Query: 133 --MMKIEEEERKKIEDMKENERIKATKALEAWKEYQRKAEEQKKIQREEKLCQKEKQIKE 190
M K EE+ R++ E M+E E + + +E Q +E++ ++EE++ ++E+Q++E
Sbjct: 255 EQMRKQEEQMREQEEQMREQEEQMLKQKEQTEQEEQTGEQEEQMREQEEQMREQEEQMRE 314
Query: 191 ERKKIKYKSLTRNLASRNLAPKGRNSENIFTEK-----LKEDSIPAPRSVGSIKINFTPR 245
+ ++++ + G+ E ++ +K KE +G + +
Sbjct: 315 QEEQMREQE----------EQMGKQEEQMWEQKEQMWEQKEQMWKQEEQMGEQEEQMQKQ 364
Query: 246 VFPTALRESQVAEEEEWLHKQAEARRAMNTDIAELCDLKEEEK 288
+E Q+ ++EE + KQ E R + E + E+K
Sbjct: 365 EEQVRKQEEQMRKQEEQMRKQEEQMRKQEEQMGEQKEQMGEQK 407
Score = 42.7 bits (99), Expect = 6e-04
Identities = 34/115 (29%), Positives = 56/115 (48%), Gaps = 14/115 (12%)
Query: 77 KKEAAMWETLSVTGVDKEMMQRIREKSILQAQERAKEATEAKAAAKREDQKYALSVMMKI 136
K+E MWE KE M + E+ Q ++ K+ + + K+E+Q M K
Sbjct: 328 KQEEQMWEQKEQMWEQKEQMWKQEEQMGEQEEQMQKQEEQVR---KQEEQ------MRKQ 378
Query: 137 EEEERKKIEDMKENERIKATKALEAWKEYQRKAEEQKKIQREEKLCQKEKQIKEE 191
EE+ RK+ E M++ E + + KE + +EQ + Q E+ QKE+ K+E
Sbjct: 379 EEQMRKQEEQMRKQE-----EQMGEQKEQMGEQKEQMREQEEQMGEQKEQMRKQE 428
Score = 40.8 bits (94), Expect = 0.002
Identities = 41/208 (19%), Positives = 85/208 (40%), Gaps = 34/208 (16%)
Query: 90 GVDKEMMQRIREKSILQAQERAKEATEAKAAAKREDQKYALSVMMKIEEEE-RKKIEDMK 148
G +E ++RE+ ++ + + + ++E+Q M +EE+ RK+ E M
Sbjct: 178 GQVREQEGQVREQEGQMGEQEGQMGEQEEQMGEQEEQMQKQEEQMGEQEEQMRKQEEQMG 237
Query: 149 ENERIKATKALEAWKEYQRKAEEQKKIQREEKLCQKEKQIKEERKKIKYKSLTRNLASRN 208
E E + ++ +E +K EEQ + Q E+ Q+E+ ++E + +K K T
Sbjct: 238 EQE-----EQVQKQEEQVQKQEEQMRKQEEQMREQEEQMREQEEQMLKQKEQTEQEEQTG 292
Query: 209 LAPKGRNSENIFTEKLKEDSIPAPRSVGSIKINFTPRVFPTALRESQVAEEEEWLHKQAE 268
+ + E+++E +E Q+ E+EE + +Q E
Sbjct: 293 EQEEQMREQE---EQMRE-------------------------QEEQMREQEEQMREQEE 324
Query: 269 ARRAMNTDIAELCDLKEEEKNPEWLKDK 296
+ E + E+K W +++
Sbjct: 325 QMGKQEEQMWEQKEQMWEQKEQMWKQEE 352
Score = 38.1 bits (87), Expect = 0.015
Identities = 34/126 (26%), Positives = 60/126 (47%), Gaps = 14/126 (11%)
Query: 77 KKEAAMWETLSVTGVDKEMMQRIREKSILQAQERAKEATEAKAAAKREDQKYALSVMMKI 136
++E M E G +E M +E+ Q ++ K+ + ++E+Q M K
Sbjct: 314 EQEEQMREQEEQMGKQEEQMWEQKEQMWEQKEQMWKQEEQM---GEQEEQ------MQKQ 364
Query: 137 EEEERKKIEDMKENERIKATKALEAWKEYQRKAEEQKKIQREEKLCQKEKQIKEERKKIK 196
EE+ RK+ E M++ E + + +E RK EEQ Q+E+ QKE+ ++E + +
Sbjct: 365 EEQVRKQEEQMRKQE-----EQMRKQEEQMRKQEEQMGEQKEQMGEQKEQMREQEEQMGE 419
Query: 197 YKSLTR 202
K R
Sbjct: 420 QKEQMR 425
Score = 37.0 bits (84), Expect = 0.034
Identities = 30/111 (27%), Positives = 56/111 (50%), Gaps = 21/111 (18%)
Query: 75 LYKKEAAMWETLSVTGVDKEMMQRIREKSILQAQERAKEATEAKAAAKREDQKYALSVMM 134
+++++ MW+ G +E MQ+ +E+ + + +E+ + K+E+Q M
Sbjct: 340 MWEQKEQMWKQEEQMGEQEEQMQK-QEEQVRKQEEQMR---------KQEEQ------MR 383
Query: 135 KIEEEERKKIEDMKENERIKATKALEAWKEYQRKAEEQKKIQREEKLCQKE 185
K EE+ RK+ E M E + + + KE R+ EEQ Q+E+ Q+E
Sbjct: 384 KQEEQMRKQEEQMGEQK-----EQMGEQKEQMREQEEQMGEQKEQMRKQEE 429
>gi|116089325 splicing factor, arginine/serine-rich 12 isoform a
[Homo sapiens]
Length = 624
Score = 54.7 bits (130), Expect = 2e-07
Identities = 53/204 (25%), Positives = 97/204 (47%), Gaps = 18/204 (8%)
Query: 97 QRIREKSILQAQERAKEATEAKAAAKREDQKYALSVMMKIEEEERKKIEDMKENERIKAT 156
+R++EK + +ER KE + K K +D+ +E E+ + +D +++ +
Sbjct: 388 ERVKEKDREKEREREKEREKEKERGKNKDRD---------KEREKDREKDKEKDRERERE 438
Query: 157 KALEAWKEYQRKAEEQKKIQREEKLCQKEKQIKEERKKIKYKSLTRNLASRNLAPKGRNS 216
K E ++ +++ E+ K+ +RE+ + K+I E+RKK K KS T S N + + R+S
Sbjct: 439 KEHEKDRDKEKEKEQDKEKEREK---DRSKEIDEKRKKDK-KSRTPP-RSYNASRRSRSS 493
Query: 217 ENIFTEKLKEDSIPAPRSVGSIKINFTPRVFPTALRESQVAEEEEWLHKQAEARRAMNTD 276
+ S +PR+ +IK + P + + E+E H R +T
Sbjct: 494 SRERRRRRSRSSSRSPRTSKTIKRKSSRSPSPRSRNKKDKKREKERDHISERRERERSTS 553
Query: 277 IAELC---DLKEE-EKNPEWLKDK 296
+ + D KE+ EKN LK+K
Sbjct: 554 MRKSSNDRDGKEKLEKNSTSLKEK 577
Score = 32.0 bits (71), Expect = 1.1
Identities = 22/112 (19%), Positives = 48/112 (42%)
Query: 106 QAQERAKEATEAKAAAKREDQKYALSVMMKIEEEERKKIEDMKENERIKATKALEAWKEY 165
++ R+K + +K+ ++R+ + R+K ++ K +K+ E K
Sbjct: 309 RSHTRSKSRSSSKSHSRRKRSQSKHRSRSHNRSRSRQKDRRRSKSPHKKRSKSRERRKSR 368
Query: 166 QRKAEEQKKIQREEKLCQKEKQIKEERKKIKYKSLTRNLASRNLAPKGRNSE 217
R K+ EK+ +KE+ +++R+K + + R K R+ E
Sbjct: 369 SRSHSRDKRKDTREKIKEKERVKEKDREKEREREKEREKEKERGKNKDRDKE 420
>gi|21040255 splicing factor, arginine/serine-rich 12 isoform b
[Homo sapiens]
Length = 508
Score = 54.7 bits (130), Expect = 2e-07
Identities = 53/204 (25%), Positives = 97/204 (47%), Gaps = 18/204 (8%)
Query: 97 QRIREKSILQAQERAKEATEAKAAAKREDQKYALSVMMKIEEEERKKIEDMKENERIKAT 156
+R++EK + +ER KE + K K +D+ +E E+ + +D +++ +
Sbjct: 272 ERVKEKDREKEREREKEREKEKERGKNKDRD---------KEREKDREKDKEKDRERERE 322
Query: 157 KALEAWKEYQRKAEEQKKIQREEKLCQKEKQIKEERKKIKYKSLTRNLASRNLAPKGRNS 216
K E ++ +++ E+ K+ +RE+ + K+I E+RKK K KS T S N + + R+S
Sbjct: 323 KEHEKDRDKEKEKEQDKEKEREK---DRSKEIDEKRKKDK-KSRTPP-RSYNASRRSRSS 377
Query: 217 ENIFTEKLKEDSIPAPRSVGSIKINFTPRVFPTALRESQVAEEEEWLHKQAEARRAMNTD 276
+ S +PR+ +IK + P + + E+E H R +T
Sbjct: 378 SRERRRRRSRSSSRSPRTSKTIKRKSSRSPSPRSRNKKDKKREKERDHISERRERERSTS 437
Query: 277 IAELC---DLKEE-EKNPEWLKDK 296
+ + D KE+ EKN LK+K
Sbjct: 438 MRKSSNDRDGKEKLEKNSTSLKEK 461
Score = 32.0 bits (71), Expect = 1.1
Identities = 22/112 (19%), Positives = 48/112 (42%)
Query: 106 QAQERAKEATEAKAAAKREDQKYALSVMMKIEEEERKKIEDMKENERIKATKALEAWKEY 165
++ R+K + +K+ ++R+ + R+K ++ K +K+ E K
Sbjct: 193 RSHTRSKSRSSSKSHSRRKRSQSKHRSRSHNRSRSRQKDRRRSKSPHKKRSKSRERRKSR 252
Query: 166 QRKAEEQKKIQREEKLCQKEKQIKEERKKIKYKSLTRNLASRNLAPKGRNSE 217
R K+ EK+ +KE+ +++R+K + + R K R+ E
Sbjct: 253 SRSHSRDKRKDTREKIKEKERVKEKDREKEREREKEREKEKERGKNKDRDKE 304
>gi|221219053 DnaJ (Hsp40) homolog, subfamily C, member 7 isoform 1
[Homo sapiens]
Length = 494
Score = 53.9 bits (128), Expect = 3e-07
Identities = 38/148 (25%), Positives = 69/148 (46%), Gaps = 8/148 (5%)
Query: 267 AEARRAMNTDIAELCDLKEEEKNPEWLKDKGNKLFATENYLAAINAYNLAIRLNNKMPLL 326
AE M EL D +E ++ E K++GN +A ++Y A N Y AI + K
Sbjct: 5 AECDVVMAATEPELLDDQEAKREAETFKEQGNAYYAKKDYNEAYNYYTKAIDMCPKNASY 64
Query: 327 YLNRAACHLKLKNLHKAIEDSSKALELLMPPVTDNANARMKAHVRRGTAFCQLELYVEGL 386
Y NRAA + L +A+ D+ +++ L ++ ++ H+R G L +
Sbjct: 65 YGNRAATLMMLGRFREALGDAQQSVRL--------DDSFVRGHLREGKCHLSLGNAMAAC 116
Query: 387 QDYEAALKIDPSNKIVQIDAEKIRNVIQ 414
+ ++ AL++D N Q + + V++
Sbjct: 117 RSFQRALELDHKNAQAQQEFKNANAVME 144
Score = 52.8 bits (125), Expect = 6e-07
Identities = 38/136 (27%), Positives = 61/136 (44%), Gaps = 12/136 (8%)
Query: 273 MNTDIAELCDLKEEEKNPEWLKDKGNKLFATENYLAAINAYNLAIRLN----NKMPLLYL 328
M D + C K + K+ GNK F NY A Y A+ ++ LY
Sbjct: 239 MAPDHEKACIACRNAKALKAKKEDGNKAFKEGNYKLAYELYTEALGIDPNNIKTNAKLYC 298
Query: 329 NRAACHLKLKNLHKAIEDSSKALELLMPPVTDNANARMKAHVRRGTAFCQLELYVEGLQD 388
NR + KL+ L AIED + A++L + +KA++RR + E Y E ++D
Sbjct: 299 NRGTVNSKLRKLDDAIEDCTNAVKL--------DDTYIKAYLRRAQCYMDTEQYEEAVRD 350
Query: 389 YEAALKIDPSNKIVQI 404
YE + + + + Q+
Sbjct: 351 YEKVYQTEKTKEHKQL 366
>gi|18375528 UPF3 regulator of nonsense transcripts homolog B
isoform 1 [Homo sapiens]
Length = 483
Score = 53.9 bits (128), Expect = 3e-07
Identities = 51/214 (23%), Positives = 100/214 (46%), Gaps = 14/214 (6%)
Query: 97 QRIREKSILQAQERAKEATEAKAAAKREDQKYALSVMMKIEEEER-KKIEDMKENERIKA 155
QR+RE+ + +ER + E K + E +K+ K ++ E+ KKI+ + E +++K
Sbjct: 208 QRMREE---KREERRRREIERKRQREEERRKWKEEEKRKRKDIEKLKKIDRIPERDKLKD 264
Query: 156 TKALEAWKEYQRKAEEQKKIQREEKLCQKEKQIKEERKKIKYKSLTRNLASRNLAPKGRN 215
++ + + ++ +++ EK +KE +E+ KK+ ++L+ AS +
Sbjct: 265 EPKIKVHRFLLQAVNQKNLLKKPEKGDEKELDKREKAKKLDKENLSDERASGQSCTLPKR 324
Query: 216 SENIFTEKLKEDSIPAPRSVGSIKINFTPRVFPTALRESQVAEEEEWLHKQAEARRAMNT 275
S++ +LK++ P R + + ++ E E L +Q E RR
Sbjct: 325 SDS----ELKDEKPKRPEDESGRDYREREREYER--DQERILRERERLKRQEEERRRQKE 378
Query: 276 --DIAELCDLKEEE--KNPEWLKDKGNKLFATEN 305
+ + KEEE K + L+DKG K +TE+
Sbjct: 379 RYEKEKTFKRKEEEMKKEKDTLRDKGKKAESTES 412
Score = 37.4 bits (85), Expect = 0.026
Identities = 31/140 (22%), Positives = 64/140 (45%), Gaps = 12/140 (8%)
Query: 91 VDKEMMQRIREKSILQAQERAKEAT-EAKAAAKREDQKY-------ALSVMMKIEEEERK 142
V + ++Q + +K++L+ E+ E + + AK+ D++ S + +
Sbjct: 270 VHRFLLQAVNQKNLLKKPEKGDEKELDKREKAKKLDKENLSDERASGQSCTLPKRSDSEL 329
Query: 143 KIEDMKENERIKATKALEAWKEYQRKAE----EQKKIQREEKLCQKEKQIKEERKKIKYK 198
K E K E E +EY+R E E+++++R+E+ +++K+ E+ K K K
Sbjct: 330 KDEKPKRPEDESGRDYREREREYERDQERILRERERLKRQEEERRRQKERYEKEKTFKRK 389
Query: 199 SLTRNLASRNLAPKGRNSEN 218
L KG+ +E+
Sbjct: 390 EEEMKKEKDTLRDKGKKAES 409
Score = 36.2 bits (82), Expect = 0.057
Identities = 30/125 (24%), Positives = 55/125 (44%), Gaps = 6/125 (4%)
Query: 94 EMMQRIREKSILQAQERAKEATEAKAAAKREDQKYALSVMMKIEEEERKKIEDMKENERI 153
E +R ++S +ER +E + RE ++ +K +EEER++ ++ E E+
Sbjct: 332 EKPKRPEDESGRDYREREREYERDQERILRERER------LKRQEEERRRQKERYEKEKT 385
Query: 154 KATKALEAWKEYQRKAEEQKKIQREEKLCQKEKQIKEERKKIKYKSLTRNLASRNLAPKG 213
K E KE ++ KK + E + EK K+E + + ++ + L G
Sbjct: 386 FKRKEEEMKKEKDTLRDKGKKAESTESIGSSEKTEKKEEVVKRDRIRNKDRPAMQLYQPG 445
Query: 214 RNSEN 218
S N
Sbjct: 446 ARSRN 450
Score = 30.0 bits (66), Expect = 4.1
Identities = 27/104 (25%), Positives = 51/104 (49%), Gaps = 8/104 (7%)
Query: 124 EDQKYALSVMMKIEEEERKKIEDMKENERIKATKALEAWKEYQRKAEEQKKIQREEKLCQ 183
+++K + +EE E K E + + K T L K QR EE+++ +R ++ +
Sbjct: 170 DNEKMTSTPETLLEEIEAKNRELIAK----KTTPLLSFLKNKQRMREEKREERRRREI-E 224
Query: 184 KEKQIKEERKKIKYKSLTRNLASRNLAPKGRNSENIFTEKLKED 227
+++Q +EER+K K + + L R E +KLK++
Sbjct: 225 RKRQREEERRKWKEEEKRKRKDIEKLKKIDRIPER---DKLKDE 265
>gi|102467242 inner centromere protein antigens 135/155kDa isoform 2
[Homo sapiens]
Length = 914
Score = 53.9 bits (128), Expect = 3e-07
Identities = 63/283 (22%), Positives = 124/283 (43%), Gaps = 17/283 (6%)
Query: 70 TIVFTLYKKEAAMWETLSVTGVDKEMMQRIREKSILQAQERAKEATEAKAAAKREDQKYA 129
T + T+ + + M T + V K ++R + L+ + KE + ++E+ +
Sbjct: 494 TFLHTVQRNQMLMTPTSAPRSVMKSFIKR---NTPLRMDPKEKERQRLENLRRKEEAEQL 550
Query: 130 LSVMMKIEEEERKKIEDMKENERIKATKALEAWKEYQRKAEEQKKIQREEKLCQKEKQIK 189
K+EE++R+++E++K + K L+A R+ EQ K ++++++ QK QI
Sbjct: 551 RR--QKVEEDKRRRLEEVKLKREERLRKVLQA-----RERVEQMKEEKKKQIEQKFAQID 603
Query: 190 EERKKIKYKSLTRNLASRNLAPKGRNSENIFTEKLKEDSIPAPRSVGSIKINFTPRVFPT 249
E+ +K K + L A + A K E + + +E+ R + ++ R
Sbjct: 604 EKTEKAKEERLAEEKAKKKAAAK--KMEEVEARRKQEEE---ARRLRWLQQEEEERRHQE 658
Query: 250 ALRESQVAEEEEWLHKQAEARRAMNTDIAELCDLKEEEKNPEWLKDKGNKLFATENYLAA 309
L++ + EE+E L K AEA+R E + + E+ + + + E LA
Sbjct: 659 LLQKKK-EEEQERLRKAAEAKRLAEQREQERREQERREQERREQERREQERREQERQLAE 717
Query: 310 INAYNLAIRLNNKMPLLYLNRAACHLKLKNLHKAIEDSSKALE 352
RL + L + A L+ + L + +E+ K E
Sbjct: 718 QERRREQERLQAERELQEREK-ALRLQKEQLQRELEEKKKKEE 759
Score = 46.6 bits (109), Expect = 4e-05
Identities = 50/230 (21%), Positives = 106/230 (46%), Gaps = 44/230 (19%)
Query: 54 YAPIDDESSKAKIGNDTIVFTLYKKEAAMWETLSVTGVDKEMMQRIREKSILQAQERAKE 113
+A ID+++ KAK + + KK+AA +++ E + QE +E
Sbjct: 599 FAQIDEKTEKAK--EERLAEEKAKKKAAA--------------KKMEEVEARRKQE--EE 640
Query: 114 ATEAKAAAKREDQKYALSVMMKIEEEERKKIEDMKENERIKATKALEAWKEYQRKAEEQK 173
A + + E+++ ++ K +EEE++++ E +R+ + E ++ +R+ E ++
Sbjct: 641 ARRLRWLQQEEEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQERREQERREQERRE 700
Query: 174 KIQREEKLCQKEKQIKEERKKIKYKSL--TRNLASRNLA---PKGRNSENIFTEKLKEDS 228
+ +RE++ ++E+Q+ E+ ++ + + L R L R A K + + +K KE+
Sbjct: 701 QERREQERREQERQLAEQERRREQERLQAERELQEREKALRLQKEQLQRELEEKKKKEEQ 760
Query: 229 IPAPRSVGSIKINFTPRVFPTALRESQVAEEEEWLHKQAE-ARRAMNTDI 277
L E Q+ EE+E K+A A +A+N +
Sbjct: 761 --------------------QRLAERQLQEEQEKKAKEAAGASKALNVTV 790
>gi|90669931 tetratricopeptide repeat domain 12 [Homo sapiens]
Length = 705
Score = 53.5 bits (127), Expect = 3e-07
Identities = 43/150 (28%), Positives = 69/150 (46%), Gaps = 16/150 (10%)
Query: 249 TALRESQVAEEEEWLHKQAEARRAMNTDIAELCDLKEEEKN-PEWLKDKGNKLFATENYL 307
TA++ ++ E +L ++ D E + E K + LK+KGN+ FA NY
Sbjct: 71 TAMKSAEEINSEAFL-------ASVEKDAKERAKRRRENKVLADALKEKGNEAFAEGNYE 123
Query: 308 AAINAYNLAIRLNNKMPLLYLNRAACHLKLKNLHKAIEDSSKALELLMPPVTDNANARMK 367
AI Y+ + M +LY NRA ++KL++ KA+ D AL+ K
Sbjct: 124 TAILRYSEGLEKLKDMKVLYTNRAQAYMKLEDYEKALVDCEWALKC--------DEKCTK 175
Query: 368 AHVRRGTAFCQLELYVEGLQDYEAALKIDP 397
A+ G A L+ Y + Y+ L+I+P
Sbjct: 176 AYFHMGKANLALKNYSVSRECYKKILEINP 205
>gi|120953300 leucine-rich repeats and IQ motif containing 1 isoform
1 [Homo sapiens]
Length = 1722
Score = 53.5 bits (127), Expect = 3e-07
Identities = 54/223 (24%), Positives = 99/223 (44%), Gaps = 26/223 (11%)
Query: 97 QRIREKSILQAQERAKEATEAKAAAKREDQKYALSVMMKIEEEERKKIE--------DMK 148
Q + S+L+ Q A +AK A QKY + +IE ++RK E K
Sbjct: 272 QEKEKNSLLKQQNNAAVKIQAKYKAFVAYQKYGPIIKEQIESKKRKAQEWKEKEAKIRQK 331
Query: 149 ENERIKATKALEAWKEYQRKAEEQKKIQREEKLCQKEKQIKEERKKI--KYKSLTRNLAS 206
E E K + + KE ++K +E+++ +RE++ +K+ +K+ER+++ K K + R AS
Sbjct: 332 EEENRKRLEEEQRIKEERKKQKEEERKRREKEYEEKKNIVKQEREQLISKEKIILREDAS 391
Query: 207 RN------LAPKGRNSENIFTEKLKEDSIPAPRSVGSIKINFTPRVFPTALRESQVAEEE 260
+ L G N++++ E + D +++ V + ES + E
Sbjct: 392 QQLIISSALKKSGYNNKHLSLEDISNDKGDIAKNLVDENSKKQEDVLLWLVEESNMKEN- 450
Query: 261 EWLHKQAEARRAMNTDIAE-------LCDLKEEEKNPEWLKDK 296
+ +Q + ++ + E L D K EEKN K +
Sbjct: 451 --VDRQTILKESIQVKLKESISSQTILADFKMEEKNENLAKKR 491
Score = 37.7 bits (86), Expect = 0.020
Identities = 48/203 (23%), Positives = 91/203 (44%), Gaps = 34/203 (16%)
Query: 92 DKEMMQRIREKSILQAQERAKEATEAKAAAKREDQKYALSVMMKIEEEERKKIEDMKENE 151
+K+ +EK L+AQ +E K + E++++ K+E +KK+E++++ E
Sbjct: 176 EKQKELEDKEKQTLKAQRDREE----KQFQEEEEKRHCWMKQFKVE---KKKLENIQKQE 228
Query: 152 RIKATKALEAWKEYQRKAEEQKKIQREEKLCQKEKQIKEERKKIKYKSLTRNLASRNLAP 211
+ K E +KE K ++K Q EE + Q++EER + K +
Sbjct: 229 QDKMND--ELYKE--EKIWKEKFKQHEEYIRNLHLQMEEERTRFK-----------DQQE 273
Query: 212 KGRNSENIFTEKLKEDSIPAPRSVGSIKINFTPRVFPTALR---ESQVAEEEEWLHKQAE 268
K +NS LK+ + A + K + + ++ ES+ + +EW K+A+
Sbjct: 274 KEKNS------LLKQQNNAAVKIQAKYKAFVAYQKYGPIIKEQIESKKRKAQEWKEKEAK 327
Query: 269 ARRAMNTD---IAELCDLKEEEK 288
R+ + + E +KEE K
Sbjct: 328 IRQKEEENRKRLEEEQRIKEERK 350
Score = 33.5 bits (75), Expect = 0.37
Identities = 14/41 (34%), Positives = 28/41 (68%)
Query: 154 KATKALEAWKEYQRKAEEQKKIQREEKLCQKEKQIKEERKK 194
K ++ EAW+E Q++ E+++K + + ++EKQ +EE +K
Sbjct: 166 KCRQSFEAWQEKQKELEDKEKQTLKAQRDREEKQFQEEEEK 206
Score = 30.0 bits (66), Expect = 4.1
Identities = 39/202 (19%), Positives = 81/202 (40%), Gaps = 8/202 (3%)
Query: 117 AKAAAKREDQKYALSVMMKIEEEERKKIED----MKENERIKATKALEAWKEYQRKAEEQ 172
AK +K ++ +EE K+ D +KE+ ++K +++ + E+
Sbjct: 423 AKNLVDENSKKQEDVLLWLVEESNMKENVDRQTILKESIQVKLKESISSQTILADFKMEE 482
Query: 173 KKIQREEKLCQKEKQIKEERKKIKYKSLTRNLASRNLAPKGRNSENIFTEKLKEDSIPAP 232
K +K C +E +K+ERK Y++ N KG E ++LK D+
Sbjct: 483 KNENLAKKRCSEEL-VKQERK---YENTDNKTELGNSDLKGNLKEQFPLQELKSDAQKEE 538
Query: 233 RSVGSIKINFTPRVFPTALRESQVAEEEEWLHKQAEARRAMNTDIAELCDLKEEEKNPEW 292
+ + + T + L +Q E + +Q + I ++ + +E+N
Sbjct: 539 KIMKHVINENTGQKTQIILGHNQEISEVKTNEEQKIIKDNQQKKIQKVEKEEIQEQNGLL 598
Query: 293 LKDKGNKLFATENYLAAINAYN 314
KDK + + + ++ + N
Sbjct: 599 YKDKDTLVISVKQRSLSLTSEN 620
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.314 0.128 0.356
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 14,610,412
Number of Sequences: 37866
Number of extensions: 643516
Number of successful extensions: 10295
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 344
Number of HSP's successfully gapped in prelim test: 685
Number of HSP's that attempted gapping in prelim test: 4089
Number of HSP's gapped (non-prelim): 3532
length of query: 420
length of database: 18,247,518
effective HSP length: 105
effective length of query: 315
effective length of database: 14,271,588
effective search space: 4495550220
effective search space used: 4495550220
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.