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Search of human proteins with 7524346
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|7524346 adenylate kinase 2 isoform b [Homo sapiens]
(232 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|7524346 adenylate kinase 2 isoform b [Homo sapiens] 461 e-130
gi|4502013 adenylate kinase 2 isoform a [Homo sapiens] 460 e-130
gi|19923437 adenylate kinase 3 [Homo sapiens] 174 6e-44
gi|53832001 adenylate kinase 3-like 1 isoform 7 [Homo sapiens] 156 2e-38
gi|53832003 adenylate kinase 3-like 1 isoform 5 [Homo sapiens] 156 2e-38
gi|8051579 adenylate kinase 3-like 1 isoform 6 [Homo sapiens] 156 2e-38
gi|4502011 adenylate kinase 1 [Homo sapiens] 104 7e-23
gi|7706497 UMP-CMP kinase 1 isoform a [Homo sapiens] 95 4e-20
gi|28144897 adenylate kinase 5 isoform 1 [Homo sapiens] 87 1e-17
gi|28144899 adenylate kinase 5 isoform 2 [Homo sapiens] 87 1e-17
gi|22749187 putative adenylate kinase-like protein C9orf98 [Homo... 82 5e-16
gi|237858799 adenylate kinase domain containing 1 isoform 1 [Hom... 62 5e-10
gi|21450759 adenylate kinase domain containing 1 isoform 2 [Homo... 62 5e-10
gi|209915597 UMP-CMP kinase 1 isoform b [Homo sapiens] 59 3e-09
gi|148727333 adenylate kinase 7 [Homo sapiens] 48 8e-06
gi|145699133 KPL2 protein isoform 1 [Homo sapiens] 39 0.003
gi|24430151 proteasome 26S ATPase subunit 1 [Homo sapiens] 35 0.042
gi|4506209 proteasome 26S ATPase subunit 2 [Homo sapiens] 33 0.27
gi|42544174 deoxythymidylate kinase (thymidylate kinase) [Homo s... 31 1.0
gi|7706557 chromosome 9 open reading frame 78 [Homo sapiens] 30 1.8
gi|31377591 sestrin 3 [Homo sapiens] 30 2.3
gi|239757701 PREDICTED: hypothetical protein XP_002345525 [Homo ... 29 3.0
gi|239752186 PREDICTED: hypothetical protein [Homo sapiens] 29 3.0
gi|239746709 PREDICTED: hypothetical protein XP_002343816 [Homo ... 29 3.0
gi|110832843 TBP-associated factor 4 [Homo sapiens] 29 3.0
gi|40806170 spastin isoform 2 [Homo sapiens] 29 3.0
gi|11875211 spastin isoform 1 [Homo sapiens] 29 3.0
gi|116642889 cyclic nucleotide gated channel beta 3 [Homo sapiens] 29 3.0
gi|75677365 dynein heavy chain domain 3 [Homo sapiens] 29 3.9
gi|239747656 PREDICTED: similar to mCG116201 [Homo sapiens] 28 6.7
>gi|7524346 adenylate kinase 2 isoform b [Homo sapiens]
Length = 232
Score = 461 bits (1187), Expect = e-130
Identities = 232/232 (100%), Positives = 232/232 (100%)
Query: 1 MAPSVPAAEPEYPKGIRAVLLGPPGAGKGTQAPRLAENFCVCHLATGDMLRAMVASGSEL 60
MAPSVPAAEPEYPKGIRAVLLGPPGAGKGTQAPRLAENFCVCHLATGDMLRAMVASGSEL
Sbjct: 1 MAPSVPAAEPEYPKGIRAVLLGPPGAGKGTQAPRLAENFCVCHLATGDMLRAMVASGSEL 60
Query: 61 GKKLKATMDAGKLVSDEMVVELIEKNLETPLCKNGFLLDGFPRTVRQAEMLDDLMEKRKE 120
GKKLKATMDAGKLVSDEMVVELIEKNLETPLCKNGFLLDGFPRTVRQAEMLDDLMEKRKE
Sbjct: 61 GKKLKATMDAGKLVSDEMVVELIEKNLETPLCKNGFLLDGFPRTVRQAEMLDDLMEKRKE 120
Query: 121 KLDSVIEFSIPDSLLIRRITGRLIHPKSGRSYHEEFNPPKEPMKDDITGEPLIRRSDDNE 180
KLDSVIEFSIPDSLLIRRITGRLIHPKSGRSYHEEFNPPKEPMKDDITGEPLIRRSDDNE
Sbjct: 121 KLDSVIEFSIPDSLLIRRITGRLIHPKSGRSYHEEFNPPKEPMKDDITGEPLIRRSDDNE 180
Query: 181 KALKIRLQAYHTQTTPLIEYYRKRGIHSAIDASQTPDVVFASILAAFSKATS 232
KALKIRLQAYHTQTTPLIEYYRKRGIHSAIDASQTPDVVFASILAAFSKATS
Sbjct: 181 KALKIRLQAYHTQTTPLIEYYRKRGIHSAIDASQTPDVVFASILAAFSKATS 232
>gi|4502013 adenylate kinase 2 isoform a [Homo sapiens]
Length = 239
Score = 460 bits (1183), Expect = e-130
Identities = 231/231 (100%), Positives = 231/231 (100%)
Query: 1 MAPSVPAAEPEYPKGIRAVLLGPPGAGKGTQAPRLAENFCVCHLATGDMLRAMVASGSEL 60
MAPSVPAAEPEYPKGIRAVLLGPPGAGKGTQAPRLAENFCVCHLATGDMLRAMVASGSEL
Sbjct: 1 MAPSVPAAEPEYPKGIRAVLLGPPGAGKGTQAPRLAENFCVCHLATGDMLRAMVASGSEL 60
Query: 61 GKKLKATMDAGKLVSDEMVVELIEKNLETPLCKNGFLLDGFPRTVRQAEMLDDLMEKRKE 120
GKKLKATMDAGKLVSDEMVVELIEKNLETPLCKNGFLLDGFPRTVRQAEMLDDLMEKRKE
Sbjct: 61 GKKLKATMDAGKLVSDEMVVELIEKNLETPLCKNGFLLDGFPRTVRQAEMLDDLMEKRKE 120
Query: 121 KLDSVIEFSIPDSLLIRRITGRLIHPKSGRSYHEEFNPPKEPMKDDITGEPLIRRSDDNE 180
KLDSVIEFSIPDSLLIRRITGRLIHPKSGRSYHEEFNPPKEPMKDDITGEPLIRRSDDNE
Sbjct: 121 KLDSVIEFSIPDSLLIRRITGRLIHPKSGRSYHEEFNPPKEPMKDDITGEPLIRRSDDNE 180
Query: 181 KALKIRLQAYHTQTTPLIEYYRKRGIHSAIDASQTPDVVFASILAAFSKAT 231
KALKIRLQAYHTQTTPLIEYYRKRGIHSAIDASQTPDVVFASILAAFSKAT
Sbjct: 181 KALKIRLQAYHTQTTPLIEYYRKRGIHSAIDASQTPDVVFASILAAFSKAT 231
>gi|19923437 adenylate kinase 3 [Homo sapiens]
Length = 227
Score = 174 bits (441), Expect = 6e-44
Identities = 89/200 (44%), Positives = 134/200 (67%), Gaps = 6/200 (3%)
Query: 16 IRAVLLGPPGAGKGTQAPRLAENFCVCHLATGDMLRAMVASGSELGKKLKATMDAGKLVS 75
+RAV++G PG+GKGT + R+ +F + HL++GD+LR + G+E+G KA +D GKL+
Sbjct: 8 LRAVIMGAPGSGKGTVSSRITTHFELKHLSSGDLLRDNMLRGTEIGVLAKAFIDQGKLIP 67
Query: 76 DEMVVELIEKNLETPLCKNGFLLDGFPRTVRQAEMLDDLMEKRKEKLDSVIEFSIPDSLL 135
D+++ L L+ L + +LLDGFPRT+ QAE LD R ++D+VI ++P ++
Sbjct: 68 DDVMTRLALHELKN-LTQYSWLLDGFPRTLPQAEALD-----RAYQIDTVINLNVPFEVI 121
Query: 136 IRRITGRLIHPKSGRSYHEEFNPPKEPMKDDITGEPLIRRSDDNEKALKIRLQAYHTQTT 195
+R+T R IHP SGR Y+ EFNPPK DD+TGEPLI+R DD + + RL+AY QT
Sbjct: 122 KQRLTARWIHPASGRVYNIEFNPPKTVGIDDLTGEPLIQREDDKPETVIKRLKAYEDQTK 181
Query: 196 PLIEYYRKRGIHSAIDASQT 215
P++EYY+K+G+ ++T
Sbjct: 182 PVLEYYQKKGVLETFSGTET 201
>gi|53832001 adenylate kinase 3-like 1 isoform 7 [Homo sapiens]
Length = 223
Score = 156 bits (394), Expect = 2e-38
Identities = 84/202 (41%), Positives = 125/202 (61%), Gaps = 6/202 (2%)
Query: 14 KGIRAVLLGPPGAGKGTQAPRLAENFCVCHLATGDMLRAMVASGSELGKKLKATMDAGKL 73
K +RAV+LGPPG+GKGT R+A+NF + HL++G LR + + +E+G+ K ++ L
Sbjct: 4 KLLRAVILGPPGSGKGTVCQRIAQNFGLQHLSSGHFLRENIKASTEVGEMAKQYIEKSLL 63
Query: 74 VSDEMVVELIEKNLETPLCKNGFLLDGFPRTVRQAEMLDDLMEKRKEKLDSVIEFSIPDS 133
V D ++ L+ LE ++ +LLDGFPRT+ QAE LD + E +D VI +IP
Sbjct: 64 VPDHVITRLMMSELENRRGQH-WLLDGFPRTLGQAEALDKICE-----VDLVISLNIPFE 117
Query: 134 LLIRRITGRLIHPKSGRSYHEEFNPPKEPMKDDITGEPLIRRSDDNEKALKIRLQAYHTQ 193
L R++ R IHP SGR Y+ +FNPP DD+TGEPL+++ DD +A+ RL+ Y
Sbjct: 118 TLKDRLSRRWIHPPSGRVYNLDFNPPHVHGIDDVTGEPLVQQEDDKPEAVAARLRQYKDV 177
Query: 194 TTPLIEYYRKRGIHSAIDASQT 215
P+IE Y+ RG+ ++T
Sbjct: 178 AKPVIELYKSRGVLHQFSGTET 199
>gi|53832003 adenylate kinase 3-like 1 isoform 5 [Homo sapiens]
Length = 223
Score = 156 bits (394), Expect = 2e-38
Identities = 84/202 (41%), Positives = 125/202 (61%), Gaps = 6/202 (2%)
Query: 14 KGIRAVLLGPPGAGKGTQAPRLAENFCVCHLATGDMLRAMVASGSELGKKLKATMDAGKL 73
K +RAV+LGPPG+GKGT R+A+NF + HL++G LR + + +E+G+ K ++ L
Sbjct: 4 KLLRAVILGPPGSGKGTVCQRIAQNFGLQHLSSGHFLRENIKASTEVGEMAKQYIEKSLL 63
Query: 74 VSDEMVVELIEKNLETPLCKNGFLLDGFPRTVRQAEMLDDLMEKRKEKLDSVIEFSIPDS 133
V D ++ L+ LE ++ +LLDGFPRT+ QAE LD + E +D VI +IP
Sbjct: 64 VPDHVITRLMMSELENRRGQH-WLLDGFPRTLGQAEALDKICE-----VDLVISLNIPFE 117
Query: 134 LLIRRITGRLIHPKSGRSYHEEFNPPKEPMKDDITGEPLIRRSDDNEKALKIRLQAYHTQ 193
L R++ R IHP SGR Y+ +FNPP DD+TGEPL+++ DD +A+ RL+ Y
Sbjct: 118 TLKDRLSRRWIHPPSGRVYNLDFNPPHVHGIDDVTGEPLVQQEDDKPEAVAARLRQYKDV 177
Query: 194 TTPLIEYYRKRGIHSAIDASQT 215
P+IE Y+ RG+ ++T
Sbjct: 178 AKPVIELYKSRGVLHQFSGTET 199
>gi|8051579 adenylate kinase 3-like 1 isoform 6 [Homo sapiens]
Length = 223
Score = 156 bits (394), Expect = 2e-38
Identities = 84/202 (41%), Positives = 125/202 (61%), Gaps = 6/202 (2%)
Query: 14 KGIRAVLLGPPGAGKGTQAPRLAENFCVCHLATGDMLRAMVASGSELGKKLKATMDAGKL 73
K +RAV+LGPPG+GKGT R+A+NF + HL++G LR + + +E+G+ K ++ L
Sbjct: 4 KLLRAVILGPPGSGKGTVCQRIAQNFGLQHLSSGHFLRENIKASTEVGEMAKQYIEKSLL 63
Query: 74 VSDEMVVELIEKNLETPLCKNGFLLDGFPRTVRQAEMLDDLMEKRKEKLDSVIEFSIPDS 133
V D ++ L+ LE ++ +LLDGFPRT+ QAE LD + E +D VI +IP
Sbjct: 64 VPDHVITRLMMSELENRRGQH-WLLDGFPRTLGQAEALDKICE-----VDLVISLNIPFE 117
Query: 134 LLIRRITGRLIHPKSGRSYHEEFNPPKEPMKDDITGEPLIRRSDDNEKALKIRLQAYHTQ 193
L R++ R IHP SGR Y+ +FNPP DD+TGEPL+++ DD +A+ RL+ Y
Sbjct: 118 TLKDRLSRRWIHPPSGRVYNLDFNPPHVHGIDDVTGEPLVQQEDDKPEAVAARLRQYKDV 177
Query: 194 TTPLIEYYRKRGIHSAIDASQT 215
P+IE Y+ RG+ ++T
Sbjct: 178 AKPVIELYKSRGVLHQFSGTET 199
>gi|4502011 adenylate kinase 1 [Homo sapiens]
Length = 194
Score = 104 bits (259), Expect = 7e-23
Identities = 65/205 (31%), Positives = 107/205 (52%), Gaps = 32/205 (15%)
Query: 20 LLGPPGAGKGTQAPRLAENFCVCHLATGDMLRAMVASGSELGKKLKATMDAGKLVSDEMV 79
++G PG+GKGTQ ++ + + HL+TGD+LR+ V+SGS GKKL M+ G+LV E V
Sbjct: 13 VVGGPGSGKGTQCEKIVQKYGYTHLSTGDLLRSEVSSGSARGKKLSEIMEKGQLVPLETV 72
Query: 80 VELIEKNLETPL-CKNGFLLDGFPRTVRQAEMLDDLMEKRKEKLDSVIEFSIPDSLLIRR 138
++++ + + GFL+DG+PR V+Q E E+R + ++ + +R
Sbjct: 73 LDMLRDAMVAKVNTSKGFLIDGYPREVQQGEE----FERRIGQPTLLLYVDAGPETMTQR 128
Query: 139 ITGRLIHPKSGRSYHEEFNPPKEPMKDDITGEPLIRRSDDNEKALKIRLQAYHTQTTPLI 198
+ R + +G R DDNE+ +K RL+ Y+ T P+I
Sbjct: 129 LLKR----------------------GETSG-----RVDDNEETIKKRLETYYKATEPVI 161
Query: 199 EYYRKRGIHSAIDASQTPDVVFASI 223
+Y KRGI ++A + D VF+ +
Sbjct: 162 AFYEKRGIVRKVNAEGSVDSVFSQV 186
>gi|7706497 UMP-CMP kinase 1 isoform a [Homo sapiens]
Length = 228
Score = 95.1 bits (235), Expect = 4e-20
Identities = 67/225 (29%), Positives = 108/225 (48%), Gaps = 33/225 (14%)
Query: 10 PEYPKGIRAVLLGPPGAGKGTQAPRLAENFCVCHLATGDMLR-AMVASGSELGKKLKATM 68
P K + +LG PGAGKGTQ R+ E + HL+ G++LR S+ G+ ++ +
Sbjct: 30 PRLMKPLVVFVLGGPGAGKGTQCARIVEKYGYTHLSAGELLRDERKNPDSQYGELIEKYI 89
Query: 69 DAGKLVSDEMVVELIEKNLETPLC----KNGFLLDGFPRTVRQAEMLDDLMEKRKEKLDS 124
GK+V E+ + L+++ ++ + KN FL+DGFPR + + M+ K +
Sbjct: 90 KEGKIVPVEITISLLKREMDQTMAANAQKNKFLIDGFPRNQDNLQGWNKTMD-GKADVSF 148
Query: 125 VIEFSIPDSLLIRRITGRLIHPKSGRSYHEEFNPPKEPMKDDITGEPLIRRSDDNEKALK 184
V+ F + + I R R G+S RSDDN ++L+
Sbjct: 149 VLFFDCNNEICIERCLER------GKS---------------------SGRSDDNRESLE 181
Query: 185 IRLQAYHTQTTPLIEYYRKRGIHSAIDASQTPDVVFASILAAFSK 229
R+Q Y T P+I+ Y + G IDAS++ D VF ++ F K
Sbjct: 182 KRIQTYLQSTKPIIDLYEEMGKVKKIDASKSVDEVFDEVVQIFDK 226
>gi|28144897 adenylate kinase 5 isoform 1 [Homo sapiens]
Length = 562
Score = 87.0 bits (214), Expect = 1e-17
Identities = 63/208 (30%), Positives = 98/208 (47%), Gaps = 32/208 (15%)
Query: 20 LLGPPGAGKGTQAPRLAENFCVCHLATGDMLRAMVASGSELGKKLKATMDAGKLVSDEMV 79
++G PG+GKGTQ +L E + HL+TG++LR +AS SE K ++ M+ G LV +V
Sbjct: 381 IIGGPGSGKGTQCEKLVEKYGFTHLSTGELLREELASESERSKLIRDIMERGDLVPSGIV 440
Query: 80 VELIEKNLETPL-CKNGFLLDGFPRTVRQAEMLDDLMEKRKEKLDSVIEFSIPDSLLIRR 138
+EL+++ + L GFL+DG+PR V+Q E +R VI + R
Sbjct: 441 LELLKEAMVASLGDTRGFLIDGYPREVKQGEEFG----RRIGDPQLVICMDCSADTMTNR 496
Query: 139 ITGRLIHPKSGRSYHEEFNPPKEPMKDDITGEPLIRRSDDNEKALKIRLQAYHTQTTPLI 198
+ R + P+ DD K + RL+AY+ + P+I
Sbjct: 497 LLQR--------------SRSSLPV-------------DDTTKTIAKRLEAYYRASIPVI 529
Query: 199 EYYRKRGIHSAIDASQTPDVVFASILAA 226
YY + I+A TP+ VF + A
Sbjct: 530 AYYETKTQLHKINAEGTPEDVFLQLCTA 557
Score = 77.0 bits (188), Expect = 1e-14
Identities = 54/220 (24%), Positives = 99/220 (45%), Gaps = 33/220 (15%)
Query: 9 EPEYPKGIRAVLLGPPGAGKGTQAPRLAENFCVCHLATGDMLRAMVASGSELGK--KLKA 66
+P P+ +++G PG+GKGTQ+ ++AE + +++ G++LR + S S K +
Sbjct: 126 DPTRPRPKIILVIGGPGSGKGTQSLKIAERYGFQYISVGELLRKKIHSTSSNRKWSLIAK 185
Query: 67 TMDAGKLVSDEMVVELIEKNLETPLCKNGFLLDGFPRTVRQAEMLDDLMEKRKEKLDSVI 126
+ G+L E + I++ L + G ++DGFPR V QA +D
Sbjct: 186 IITTGELAPQETTITEIKQKLMQIPDEEGIVIDGFPRDVAQALSFED------------- 232
Query: 127 EFSIPDSLLIRRITGRLIHPKSGRSYHEEFNPPKEPMKDDITGEPLIRRSDDNEKALKIR 186
+ PD ++ + + + + ++ P DDN KA + R
Sbjct: 233 QICTPDLVVFLACANQRLKERLLKRAEQQGRP------------------DDNVKATQRR 274
Query: 187 LQAYHTQTTPLIEYYRKRGIHSAIDASQTPDVVFASILAA 226
L + PL++Y++++G+ DA + D VF I A
Sbjct: 275 LMNFKQNAAPLVKYFQEKGLIMTFDADRDEDEVFYDISMA 314
>gi|28144899 adenylate kinase 5 isoform 2 [Homo sapiens]
Length = 536
Score = 87.0 bits (214), Expect = 1e-17
Identities = 63/208 (30%), Positives = 98/208 (47%), Gaps = 32/208 (15%)
Query: 20 LLGPPGAGKGTQAPRLAENFCVCHLATGDMLRAMVASGSELGKKLKATMDAGKLVSDEMV 79
++G PG+GKGTQ +L E + HL+TG++LR +AS SE K ++ M+ G LV +V
Sbjct: 355 IIGGPGSGKGTQCEKLVEKYGFTHLSTGELLREELASESERSKLIRDIMERGDLVPSGIV 414
Query: 80 VELIEKNLETPL-CKNGFLLDGFPRTVRQAEMLDDLMEKRKEKLDSVIEFSIPDSLLIRR 138
+EL+++ + L GFL+DG+PR V+Q E +R VI + R
Sbjct: 415 LELLKEAMVASLGDTRGFLIDGYPREVKQGEEFG----RRIGDPQLVICMDCSADTMTNR 470
Query: 139 ITGRLIHPKSGRSYHEEFNPPKEPMKDDITGEPLIRRSDDNEKALKIRLQAYHTQTTPLI 198
+ R + P+ DD K + RL+AY+ + P+I
Sbjct: 471 LLQR--------------SRSSLPV-------------DDTTKTIAKRLEAYYRASIPVI 503
Query: 199 EYYRKRGIHSAIDASQTPDVVFASILAA 226
YY + I+A TP+ VF + A
Sbjct: 504 AYYETKTQLHKINAEGTPEDVFLQLCTA 531
Score = 77.0 bits (188), Expect = 1e-14
Identities = 54/220 (24%), Positives = 99/220 (45%), Gaps = 33/220 (15%)
Query: 9 EPEYPKGIRAVLLGPPGAGKGTQAPRLAENFCVCHLATGDMLRAMVASGSELGK--KLKA 66
+P P+ +++G PG+GKGTQ+ ++AE + +++ G++LR + S S K +
Sbjct: 100 DPTRPRPKIILVIGGPGSGKGTQSLKIAERYGFQYISVGELLRKKIHSTSSNRKWSLIAK 159
Query: 67 TMDAGKLVSDEMVVELIEKNLETPLCKNGFLLDGFPRTVRQAEMLDDLMEKRKEKLDSVI 126
+ G+L E + I++ L + G ++DGFPR V QA +D
Sbjct: 160 IITTGELAPQETTITEIKQKLMQIPDEEGIVIDGFPRDVAQALSFED------------- 206
Query: 127 EFSIPDSLLIRRITGRLIHPKSGRSYHEEFNPPKEPMKDDITGEPLIRRSDDNEKALKIR 186
+ PD ++ + + + + ++ P DDN KA + R
Sbjct: 207 QICTPDLVVFLACANQRLKERLLKRAEQQGRP------------------DDNVKATQRR 248
Query: 187 LQAYHTQTTPLIEYYRKRGIHSAIDASQTPDVVFASILAA 226
L + PL++Y++++G+ DA + D VF I A
Sbjct: 249 LMNFKQNAAPLVKYFQEKGLIMTFDADRDEDEVFYDISMA 288
>gi|22749187 putative adenylate kinase-like protein C9orf98 [Homo
sapiens]
Length = 479
Score = 81.6 bits (200), Expect = 5e-16
Identities = 55/208 (26%), Positives = 105/208 (50%), Gaps = 12/208 (5%)
Query: 17 RAVLLGPPGAGKGTQAPRLAENFCVCHLATGDMLRAMVASGSELGKKLKATMDAGKLVSD 76
R +LLGP G+GK QA LA+ + + ++ G +L+ VA + G+ ++ + V D
Sbjct: 270 RVLLLGPVGSGKSLQAALLAQKYRLVNVCCGQLLKEAVADRTTFGELIQPFFEKEMAVPD 329
Query: 77 EMVVELIEKNLETPLC-KNGFLLDGFPRTVRQAEMLDDLMEKRKEKLDSVIEFSIPDSLL 135
++++++ + L+ C + G++L G PR + QA +L+ L + V ++P +
Sbjct: 330 SLLMKVLSQRLDQQDCIQKGWVLHGVPRDLDQAHLLNRL----GYNPNRVFFLNVPFDSI 385
Query: 136 IRRITGRLIHPKSGRSYHEEFNPPKEPMKDDITGEPLIRRSDDNEKALKIRLQAYHTQTT 195
+ R+T R I P +G YH + PP P + L++ D E+ +K+++ ++ +
Sbjct: 386 MERLTLRRIDPVTGERYHLMYKPP--PTME--IQARLLQNPKDAEEQVKLKMDLFYRNSA 441
Query: 196 PLIEYYRKRGIHSAIDASQTPDVVFASI 223
L + Y G ++ Q P VF I
Sbjct: 442 DLEQLY---GSAITLNGDQDPYTVFEYI 466
Score = 67.0 bits (162), Expect = 1e-11
Identities = 63/210 (30%), Positives = 97/210 (46%), Gaps = 16/210 (7%)
Query: 17 RAVLLGPPGAGKGTQAPRLAENFCVCHLATGDMLRAMVASGSELGKKLKATMDAGKLVSD 76
R V+LGPP +GK T A L ++ L +++ + + ++L K V
Sbjct: 59 RIVILGPPASGKTTIAMWLCKHLNSSLLTLENLILNEFSYTATEARRLYLQR---KTVPS 115
Query: 77 EMVVELIEKNLETPLC-KNGFLLDGFPRTVRQAEMLDDLMEKRKEKLDSVIEFSIPDSLL 135
++V+LI++ L C K G++LDG P T QA + L + VI S PD++L
Sbjct: 116 ALLVQLIQERLAEEDCIKQGWILDGIPETREQALRIQTLGITPRH----VIVLSAPDTVL 171
Query: 136 IRRITGRLIHPKSGRSYHEEFN-PPKEPMKDDITGEPLIRRSDDNEKALKIRLQAYHTQT 194
I R G+ I P++G YH F+ PP+ +++ L+ D +E +L YH
Sbjct: 172 IERNLGKRIDPQTGEIYHTTFDWPPESEIQN-----RLMVPEDISELETAQKLLEYHRNI 226
Query: 195 TPLIEYYRKRGIHSAIDASQTPDVVFASIL 224
+I Y K I I A Q VF L
Sbjct: 227 VRVIPSYPK--ILKVISADQPCVDVFYQAL 254
>gi|237858799 adenylate kinase domain containing 1 isoform 1 [Homo
sapiens]
Length = 1911
Score = 61.6 bits (148), Expect = 5e-10
Identities = 49/193 (25%), Positives = 92/193 (47%), Gaps = 22/193 (11%)
Query: 14 KGIRAVLLGPPGAGKGTQAPRLAENFCVCHLATGDMLRAMVASGSELGKKLKATMDAGKL 73
K + V+ G PG GK T A + + + + +L +A+ +E G L++ + +G+
Sbjct: 29 KPVCFVVFGKPGVGKTTLARYITQAWKCIRVEALPILEEQIAAETESGVMLQSMLISGQS 88
Query: 74 VSDEMVVELIEKNLETP-LCKNGFLLDGFP-------RTVRQAEMLDDLMEKRKEKLDSV 125
+ DE+V++L+ + L +P +C G+++ P T++Q E++ +L K D +
Sbjct: 89 IPDELVIKLMLEKLNSPEVCHFGYIITEIPSLSQDAMTTLQQIELIKNL----NLKPDVI 144
Query: 126 IEFSIPDSLLIRRITGRLIHPKSGRSY-HEEFNP---------PKEPMKDDITGEPLIRR 175
I PD L +RI+G+ H +G Y ++++P KE KD E
Sbjct: 145 INIKCPDYDLCQRISGQRQHNNTGYIYSRDQWDPEVIENHRKKKKEAQKDGKGEEEEEEE 204
Query: 176 SDDNEKALKIRLQ 188
+ E+A +Q
Sbjct: 205 EQEEEEAFIAEMQ 217
Score = 60.5 bits (145), Expect = 1e-09
Identities = 39/137 (28%), Positives = 70/137 (51%), Gaps = 9/137 (6%)
Query: 6 PAAEPEYPKGIRAVLLGPPGAGKGTQAPRLAENFCVCHLATGDMLRAMVAS--GSELGKK 63
P +P P IR +++GPP +GK T A ++ + + HL+ G LR ++ + +EL
Sbjct: 1404 PKPKPTVP--IRIIIVGPPKSGKTTVAKKITSEYGLKHLSIGGALRYVLNNHPETELALM 1461
Query: 64 LKATMDAGKLVSDEMVVELIEKNLETPLCKN-GFLLDGFPRTVRQAEMLDDLMEKRKEKL 122
L + G DE+ ++ +E +L +C G ++DG+P T Q +L+E R
Sbjct: 1462 LNWHLHKGMTAPDELAIQALELSLMESVCNTAGVVIDGYPVTKHQM----NLLEARSIIP 1517
Query: 123 DSVIEFSIPDSLLIRRI 139
+ E S+P + +R+
Sbjct: 1518 MVIFELSVPSKEIFKRL 1534
Score = 33.9 bits (76), Expect = 0.12
Identities = 36/154 (23%), Positives = 58/154 (37%), Gaps = 49/154 (31%)
Query: 9 EPEYPKGIRAVLLGPPGAGKGTQAPRLAENFCVCHLATGDMLRAMV-------------- 54
EP +R L+GP G+GK +LAE + H+ ++L+ +
Sbjct: 985 EPLKAPPLRICLVGPQGSGKTMCGRQLAEKLNIFHIQFEEVLQEKLLLKTEKKVGPEFEE 1044
Query: 55 ------ASGSELGK------------KLKATMDAGKLVSDEMVVE--------------- 81
A+ EL + K + +L +E V++
Sbjct: 1045 DSENEQAAKQELEELAIQANVKVEEENTKKQLPEVQLTEEEEVIKSSLMENEPLPPEILE 1104
Query: 82 --LIEKNLETPLCKNGFLLDGFPRTVRQAEMLDD 113
L E L+ P+ GF+LDGFPR +A+ L D
Sbjct: 1105 VILSEWWLKEPIRSTGFILDGFPRYPEEAQFLGD 1138
>gi|21450759 adenylate kinase domain containing 1 isoform 2 [Homo
sapiens]
Length = 421
Score = 61.6 bits (148), Expect = 5e-10
Identities = 49/193 (25%), Positives = 92/193 (47%), Gaps = 22/193 (11%)
Query: 14 KGIRAVLLGPPGAGKGTQAPRLAENFCVCHLATGDMLRAMVASGSELGKKLKATMDAGKL 73
K + V+ G PG GK T A + + + + +L +A+ +E G L++ + +G+
Sbjct: 29 KPVCFVVFGKPGVGKTTLARYITQAWKCIRVEALPILEEQIAAETESGVMLQSMLISGQS 88
Query: 74 VSDEMVVELIEKNLETP-LCKNGFLLDGFP-------RTVRQAEMLDDLMEKRKEKLDSV 125
+ DE+V++L+ + L +P +C G+++ P T++Q E++ +L K D +
Sbjct: 89 IPDELVIKLMLEKLNSPEVCHFGYIITEIPSLSQDAMTTLQQIELIKNL----NLKPDVI 144
Query: 126 IEFSIPDSLLIRRITGRLIHPKSGRSY-HEEFNP---------PKEPMKDDITGEPLIRR 175
I PD L +RI+G+ H +G Y ++++P KE KD E
Sbjct: 145 INIKCPDYDLCQRISGQRQHNNTGYIYSRDQWDPEVIENHRKKKKEAQKDGKGEEEEEEE 204
Query: 176 SDDNEKALKIRLQ 188
+ E+A +Q
Sbjct: 205 EQEEEEAFIAEMQ 217
>gi|209915597 UMP-CMP kinase 1 isoform b [Homo sapiens]
Length = 179
Score = 59.3 bits (142), Expect = 3e-09
Identities = 56/220 (25%), Positives = 83/220 (37%), Gaps = 72/220 (32%)
Query: 10 PEYPKGIRAVLLGPPGAGKGTQAPRLAENFCVCHLATGDMLRAMVASGSELGKKLKATMD 69
P K + +LG PGAGKGTQ R
Sbjct: 30 PRLMKPLVVFVLGGPGAGKGTQCAR----------------------------------- 54
Query: 70 AGKLVSDEMVVELIEKNLETPLCKNGFLLDGFPRTVRQAEMLDDLMEKRKEKLDSVIEFS 129
+VE +++ + KN FL+DGFPR + + M+ K + V+ F
Sbjct: 55 ---------IVEEMDQTMAANAQKNKFLIDGFPRNQDNLQGWNKTMD-GKADVSFVLFFD 104
Query: 130 IPDSLLIRRITGRLIHPKSGRSYHEEFNPPKEPMKDDITGEPLIRRSDDNEKALKIRLQA 189
+ + I R R G+S RSDDN ++L+ R+Q
Sbjct: 105 CNNEICIERCLER------GKS---------------------SGRSDDNRESLEKRIQT 137
Query: 190 YHTQTTPLIEYYRKRGIHSAIDASQTPDVVFASILAAFSK 229
Y T P+I+ Y + G IDAS++ D VF ++ F K
Sbjct: 138 YLQSTKPIIDLYEEMGKVKKIDASKSVDEVFDEVVQIFDK 177
>gi|148727333 adenylate kinase 7 [Homo sapiens]
Length = 723
Score = 47.8 bits (112), Expect = 8e-06
Identities = 35/136 (25%), Positives = 65/136 (47%), Gaps = 32/136 (23%)
Query: 16 IRAVLLGPPGAGKGTQAPRLAENFCVCHLATGDMLRAMVAS------------------- 56
I+ +LGPP GK + A LA + + H+ D++ +A
Sbjct: 368 IKICILGPPAVGKSSIAKELANYYKLHHIQLKDVISEAIAKLEAIVAPNDVGEGEEEVEE 427
Query: 57 ---------GSELGKKLKATMD--AGKLVSDEMVVELIEKNLETPLCKN-GFLLDGFPRT 104
EL +K +M+ AG+L D+ ++ +++ L++ C+N G++LDGFP+T
Sbjct: 428 EEEEENVEDAQELLDGIKESMEQNAGQL-DDQYIIRFMKEKLKSMPCRNQGYILDGFPKT 486
Query: 105 VRQAEMLDDLMEKRKE 120
QA+ L + ++ +E
Sbjct: 487 YDQAKDLFNQEDEEEE 502
>gi|145699133 KPL2 protein isoform 1 [Homo sapiens]
Length = 1822
Score = 39.3 bits (90), Expect = 0.003
Identities = 19/68 (27%), Positives = 36/68 (52%)
Query: 58 SELGKKLKATMDAGKLVSDEMVVELIEKNLETPLCKNGFLLDGFPRTVRQAEMLDDLMEK 117
++LG K + + GK + D ++V++I + +LDGFP T+ QA++L++ +
Sbjct: 684 AQLGAKSEQLLKKGKSIPDVLLVDIIVNAINEIPVNQDCILDGFPMTLNQAQLLEEALTG 743
Query: 118 RKEKLDSV 125
L V
Sbjct: 744 CNRNLTEV 751
>gi|24430151 proteasome 26S ATPase subunit 1 [Homo sapiens]
Length = 440
Score = 35.4 bits (80), Expect = 0.042
Identities = 47/204 (23%), Positives = 80/204 (39%), Gaps = 47/204 (23%)
Query: 5 VPAAEPEY--------PKGIRAVLLGPPGAGKGTQAPRLAENFCVCHLAT--GDMLRAMV 54
+P PEY PKG+ +L GPPG GK A +A L ++++ +
Sbjct: 203 LPLTHPEYYEEMGIKPPKGV--ILYGPPGTGKTLLAKAVANQTSATFLRVVGSELIQKYL 260
Query: 55 ASGSELGKKL--KATMDAGKLVSDEMVVEL----------IEKNLETPLCKNGFLLDGFP 102
G +L ++L A A +V + + + E+ ++ + + LDGF
Sbjct: 261 GDGPKLVRELFRVAEEHAPSIVFIDEIDAIGTKRYDSNSGGEREIQRTMLELLNQLDGFD 320
Query: 103 --------RTVRQAEMLDDLMEKRKEKLDSVIEFSIPDSLLIRRITGRLIHPKSGRSYHE 154
+ E LD + R ++D IEF +PD +RI
Sbjct: 321 SRGDVKVIMATNRIETLDPAL-IRPGRIDRKIEFPLPDEKTKKRIF-------------- 365
Query: 155 EFNPPKEPMKDDITGEPLIRRSDD 178
+ + + + DD+T + LI DD
Sbjct: 366 QIHTSRMTLADDVTLDDLIMAKDD 389
>gi|4506209 proteasome 26S ATPase subunit 2 [Homo sapiens]
Length = 433
Score = 32.7 bits (73), Expect = 0.27
Identities = 39/146 (26%), Positives = 65/146 (44%), Gaps = 29/146 (19%)
Query: 11 EYPKGIRAVLLGPPGAGKGTQAPRLAE--NFCVCHLATGDMLRAMVASGSELGKKL---K 65
E PKG+ +L GPPG GK A +A + C + ++++ V G+ + ++L
Sbjct: 207 EPPKGV--LLFGPPGTGKTLCARAVANRTDACFIRVIGSELVQKYVGEGARMVRELFEMA 264
Query: 66 ATMDAGKLVSDEMVVELI-----------EKNLETPLCKNGFLLDGF-PR-------TVR 106
T A + DE ++ I + ++ + + LDGF PR
Sbjct: 265 RTKKACLIFFDE--IDAIGGARFDDGAGGDNEVQRTMLELINQLDGFDPRGNIKVLMATN 322
Query: 107 QAEMLDDLMEKRKEKLDSVIEFSIPD 132
+ + LD + R +LD IEFS+PD
Sbjct: 323 RPDTLDPAL-MRPGRLDRKIEFSLPD 347
>gi|42544174 deoxythymidylate kinase (thymidylate kinase) [Homo
sapiens]
Length = 212
Score = 30.8 bits (68), Expect = 1.0
Identities = 29/83 (34%), Positives = 39/83 (46%), Gaps = 6/83 (7%)
Query: 14 KGIRAVLLGPPGAGKGTQAPRLAENFCVC-HLATGDMLRAMVASGSELGKKLKATMDAGK 72
+G VL G AGK TQ+ +L E C H A ++LR S +E+GK L + +
Sbjct: 5 RGALIVLEGVDRAGKSTQSRKLVEALCAAGHRA--ELLRFPERS-TEIGKLLSSYLQKKS 61
Query: 73 LVSDEMVVELIEKNL--ETPLCK 93
V D V L N + PL K
Sbjct: 62 DVEDHSVHLLFSANRWEQVPLIK 84
>gi|7706557 chromosome 9 open reading frame 78 [Homo sapiens]
Length = 289
Score = 30.0 bits (66), Expect = 1.8
Identities = 21/68 (30%), Positives = 32/68 (47%), Gaps = 10/68 (14%)
Query: 114 LMEKRKEKLDSVIEFSIPDSLLIRRITGRLIHPKSGRSYHEEFNPPKEPMKDDITGEPLI 173
L E++ +K DS F +P ++ + + + R YHEE N P K++ PL
Sbjct: 198 LAEQQNKKKDSETSF-VPTNMAVNYV-------QHNRFYHEELNAPIRRNKEEPKARPL- 248
Query: 174 RRSDDNEK 181
R D EK
Sbjct: 249 -RVGDTEK 255
>gi|31377591 sestrin 3 [Homo sapiens]
Length = 492
Score = 29.6 bits (65), Expect = 2.3
Identities = 21/77 (27%), Positives = 31/77 (40%), Gaps = 20/77 (25%)
Query: 6 PAAEPEYPKGIRAVLLGPPGAGKGTQAPRLAENFCVCHLATGDMLRAMVASGSELG---- 61
P +PE G R + + NFCVC LA + + SGS G
Sbjct: 214 PERDPEISNGFRLISVN---------------NFCVCDLANDNNIENASLSGSNFGIVDS 258
Query: 62 -KKLKATMDAGKLVSDE 77
+L+A M+ K + +E
Sbjct: 259 LSELEALMERMKRLQEE 275
>gi|239757701 PREDICTED: hypothetical protein XP_002345525 [Homo
sapiens]
Length = 180
Score = 29.3 bits (64), Expect = 3.0
Identities = 14/39 (35%), Positives = 19/39 (48%)
Query: 23 PPGAGKGTQAPRLAENFCVCHLATGDMLRAMVASGSELG 61
PPG G+G Q +L +G L+ M ASG + G
Sbjct: 74 PPGTGRGPQRSPPISRMLDTNLLSGSSLQQMAASGKKAG 112
>gi|239752186 PREDICTED: hypothetical protein [Homo sapiens]
Length = 180
Score = 29.3 bits (64), Expect = 3.0
Identities = 14/39 (35%), Positives = 19/39 (48%)
Query: 23 PPGAGKGTQAPRLAENFCVCHLATGDMLRAMVASGSELG 61
PPG G+G Q +L +G L+ M ASG + G
Sbjct: 74 PPGTGRGPQRSPPISRMLDTNLLSGSSLQQMAASGKKAG 112
>gi|239746709 PREDICTED: hypothetical protein XP_002343816 [Homo
sapiens]
Length = 180
Score = 29.3 bits (64), Expect = 3.0
Identities = 14/39 (35%), Positives = 19/39 (48%)
Query: 23 PPGAGKGTQAPRLAENFCVCHLATGDMLRAMVASGSELG 61
PPG G+G Q +L +G L+ M ASG + G
Sbjct: 74 PPGTGRGPQRSPPISRMLDTNLLSGSSLQQMAASGKKAG 112
>gi|110832843 TBP-associated factor 4 [Homo sapiens]
Length = 1085
Score = 29.3 bits (64), Expect = 3.0
Identities = 17/34 (50%), Positives = 18/34 (52%), Gaps = 2/34 (5%)
Query: 2 APSVPAAEPEYPKGIRAVLLGPPG--AGKGTQAP 33
AP+ PAA P P A L PPG AG T AP
Sbjct: 262 APAAPAAAPPPPPPAPATLARPPGHPAGPPTAAP 295
>gi|40806170 spastin isoform 2 [Homo sapiens]
Length = 584
Score = 29.3 bits (64), Expect = 3.0
Identities = 21/69 (30%), Positives = 32/69 (46%), Gaps = 7/69 (10%)
Query: 5 VPAAEPEYPKGIRA-----VLLGPPGAGKGTQAPRLA--ENFCVCHLATGDMLRAMVASG 57
+P+ PE G+RA +L GPPG GK A +A N +++ + V G
Sbjct: 328 LPSLRPELFTGLRAPARGLLLFGPPGNGKTMLAKAVAAESNATFFNISAASLTSKYVGEG 387
Query: 58 SELGKKLKA 66
+L + L A
Sbjct: 388 EKLVRALFA 396
>gi|11875211 spastin isoform 1 [Homo sapiens]
Length = 616
Score = 29.3 bits (64), Expect = 3.0
Identities = 21/69 (30%), Positives = 32/69 (46%), Gaps = 7/69 (10%)
Query: 5 VPAAEPEYPKGIRA-----VLLGPPGAGKGTQAPRLA--ENFCVCHLATGDMLRAMVASG 57
+P+ PE G+RA +L GPPG GK A +A N +++ + V G
Sbjct: 360 LPSLRPELFTGLRAPARGLLLFGPPGNGKTMLAKAVAAESNATFFNISAASLTSKYVGEG 419
Query: 58 SELGKKLKA 66
+L + L A
Sbjct: 420 EKLVRALFA 428
>gi|116642889 cyclic nucleotide gated channel beta 3 [Homo sapiens]
Length = 809
Score = 29.3 bits (64), Expect = 3.0
Identities = 19/78 (24%), Positives = 34/78 (43%)
Query: 135 LIRRITGRLIHPKSGRSYHEEFNPPKEPMKDDITGEPLIRRSDDNEKALKIRLQAYHTQT 194
L++R+ R K + +P P T P ++ SDD RL + +
Sbjct: 135 LVKRMRQRTALYKKKLVEGDLSSPEASPQTAKPTAVPPVKESDDKPTEHYYRLLWFKVKK 194
Query: 195 TPLIEYYRKRGIHSAIDA 212
PL EY ++ + ++ID+
Sbjct: 195 MPLTEYLKRIKLPNSIDS 212
>gi|75677365 dynein heavy chain domain 3 [Homo sapiens]
Length = 4427
Score = 28.9 bits (63), Expect = 3.9
Identities = 18/77 (23%), Positives = 38/77 (49%), Gaps = 7/77 (9%)
Query: 21 LGPPGAGKGTQAPRLAENFCVCHLATGDMLRAMVASGSELGKKL----KATMDAGKLVSD 76
+GPPG G+ +PRL F + ++ + + G+ + +KL + G +V++
Sbjct: 2531 MGPPGGGRTVISPRLRSRFNIINMTFPTKSQIIRIFGTMINQKLQDFEEEVKPIGNVVTE 2590
Query: 77 ---EMVVELIEKNLETP 90
+M ++++ L TP
Sbjct: 2591 ATLDMYNTVVQRFLPTP 2607
>gi|239747656 PREDICTED: similar to mCG116201 [Homo sapiens]
Length = 591
Score = 28.1 bits (61), Expect = 6.7
Identities = 14/37 (37%), Positives = 19/37 (51%)
Query: 11 EYPKGIRAVLLGPPGAGKGTQAPRLAENFCVCHLATG 47
E+PK R + PPG +G +AP A C +A G
Sbjct: 514 EHPKDGRKGSVHPPGPPRGLRAPPRAAARAPCEMAVG 550
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.317 0.135 0.384
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 9,439,750
Number of Sequences: 37866
Number of extensions: 443705
Number of successful extensions: 1426
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 25
Number of HSP's successfully gapped in prelim test: 16
Number of HSP's that attempted gapping in prelim test: 1358
Number of HSP's gapped (non-prelim): 61
length of query: 232
length of database: 18,247,518
effective HSP length: 99
effective length of query: 133
effective length of database: 14,498,784
effective search space: 1928338272
effective search space used: 1928338272
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 60 (27.7 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.