Guide to the Human Genome
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Search of human proteins with 74275350

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|74275350 translocator protein isoform PBR [Homo sapiens]
         (169 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|74275350 translocator protein isoform PBR [Homo sapiens]           373   e-104
gi|229577236 benzodiazapine receptor (peripheral)-like 1 [Homo s...   115   2e-26
gi|58197560 benzodiazapine receptor (peripheral)-like 1 [Homo sa...   115   2e-26
gi|238814326 solute carrier family 22, member 20 [Homo sapiens]        30   1.3  
gi|239757095 PREDICTED: similar to hCG2005276 [Homo sapiens]           29   2.2  
gi|239751601 PREDICTED: hypothetical protein XP_002347933 [Homo ...    29   2.2  
gi|239746116 PREDICTED: hypothetical protein XP_002344200 [Homo ...    29   2.2  
gi|223890219 RNA binding motif protein, X-linked-like 3 [Homo sa...    28   2.9  
gi|195539343 elongation of very long chain fatty acids-like 6 [H...    28   3.8  
gi|13129088 elongation of very long chain fatty acids-like 6 [Ho...    28   3.8  
gi|197927448 WD repeat domain 6 protein [Homo sapiens]                 28   3.8  
gi|14249552 disrupted in renal carcinoma 2 [Homo sapiens]              28   3.8  
gi|22027554 voltage-dependent calcium channel gamma-6 subunit is...    28   3.8  
gi|22027560 voltage-dependent calcium channel gamma-6 subunit is...    28   3.8  
gi|22027557 voltage-dependent calcium channel gamma-6 subunit is...    28   3.8  
gi|4826645 aquaporin 3 [Homo sapiens]                                  28   4.9  
gi|9256602 protocadherin beta 10 precursor [Homo sapiens]              28   4.9  
gi|14195616 protocadherin beta 9 precursor [Homo sapiens]              28   4.9  
gi|21389403 folliculin isoform 2 [Homo sapiens]                        27   6.4  
gi|22907034 folliculin isoform 1 [Homo sapiens]                        27   6.4  
gi|157739945 tetratricopeptide repeat, ankyrin repeat and coiled...    27   6.4  
gi|225543463 tetratricopeptide repeat, ankyrin repeat and coiled...    27   8.4  
gi|225543461 tetratricopeptide repeat, ankyrin repeat and coiled...    27   8.4  
gi|239747360 PREDICTED: hypothetical protein [Homo sapiens]            27   8.4  
gi|239741185 PREDICTED: hypothetical protein XP_002342152 [Homo ...    27   8.4  

>gi|74275350 translocator protein isoform PBR [Homo sapiens]
          Length = 169

 Score =  373 bits (958), Expect = e-104
 Identities = 169/169 (100%), Positives = 169/169 (100%)

Query: 1   MAPPWVPAMGFTLAPSLGCFVGSRFVHGEGLRWYAGLQKPSWHPPHWVLGPVWGTLYSAM 60
           MAPPWVPAMGFTLAPSLGCFVGSRFVHGEGLRWYAGLQKPSWHPPHWVLGPVWGTLYSAM
Sbjct: 1   MAPPWVPAMGFTLAPSLGCFVGSRFVHGEGLRWYAGLQKPSWHPPHWVLGPVWGTLYSAM 60

Query: 61  GYGSYLVWKELGGFTEKAVVPLGLYTGQLALNWAWPPIFFGARQMGWALVDLLLVSGAAA 120
           GYGSYLVWKELGGFTEKAVVPLGLYTGQLALNWAWPPIFFGARQMGWALVDLLLVSGAAA
Sbjct: 61  GYGSYLVWKELGGFTEKAVVPLGLYTGQLALNWAWPPIFFGARQMGWALVDLLLVSGAAA 120

Query: 121 ATTVAWYQVSPLAARLLYPYLAWLAFTTTLNYCVWRDNHGWRGGRRLPE 169
           ATTVAWYQVSPLAARLLYPYLAWLAFTTTLNYCVWRDNHGWRGGRRLPE
Sbjct: 121 ATTVAWYQVSPLAARLLYPYLAWLAFTTTLNYCVWRDNHGWRGGRRLPE 169


>gi|229577236 benzodiazapine receptor (peripheral)-like 1 [Homo
           sapiens]
          Length = 170

 Score =  115 bits (288), Expect = 2e-26
 Identities = 63/149 (42%), Positives = 83/149 (55%), Gaps = 1/149 (0%)

Query: 11  FTLAPSLGCFVGSRFVHGEGLRWYAGLQKPSWHPPHWVLGPVWGTLYSAMGYGSYLVWKE 70
           F L P LG  +   F       W  G +  SW P + VL  V   +YS +GY SYLVWK+
Sbjct: 8   FVLLPHLGPILVWLFTRDHMSGWCEGPRMLSWCPFYKVLLLVQTAIYSVVGYASYLVWKD 67

Query: 71  LGG-FTEKAVVPLGLYTGQLALNWAWPPIFFGARQMGWALVDLLLVSGAAAATTVAWYQV 129
           LGG       +PLGLY  QL ++W    +FF     G AL+ LLL+ G   +T + W+ +
Sbjct: 68  LGGGLGWPLALPLGLYAVQLTISWTVLVLFFTVHNPGLALLHLLLLYGLVVSTALIWHPI 127

Query: 130 SPLAARLLYPYLAWLAFTTTLNYCVWRDN 158
           + LAA LL PYLAWL  T+ L Y +WRD+
Sbjct: 128 NKLAALLLLPYLAWLTVTSALTYHLWRDS 156


>gi|58197560 benzodiazapine receptor (peripheral)-like 1 [Homo
           sapiens]
          Length = 170

 Score =  115 bits (288), Expect = 2e-26
 Identities = 63/149 (42%), Positives = 83/149 (55%), Gaps = 1/149 (0%)

Query: 11  FTLAPSLGCFVGSRFVHGEGLRWYAGLQKPSWHPPHWVLGPVWGTLYSAMGYGSYLVWKE 70
           F L P LG  +   F       W  G +  SW P + VL  V   +YS +GY SYLVWK+
Sbjct: 8   FVLLPHLGPILVWLFTRDHMSGWCEGPRMLSWCPFYKVLLLVQTAIYSVVGYASYLVWKD 67

Query: 71  LGG-FTEKAVVPLGLYTGQLALNWAWPPIFFGARQMGWALVDLLLVSGAAAATTVAWYQV 129
           LGG       +PLGLY  QL ++W    +FF     G AL+ LLL+ G   +T + W+ +
Sbjct: 68  LGGGLGWPLALPLGLYAVQLTISWTVLVLFFTVHNPGLALLHLLLLYGLVVSTALIWHPI 127

Query: 130 SPLAARLLYPYLAWLAFTTTLNYCVWRDN 158
           + LAA LL PYLAWL  T+ L Y +WRD+
Sbjct: 128 NKLAALLLLPYLAWLTVTSALTYHLWRDS 156


>gi|238814326 solute carrier family 22, member 20 [Homo sapiens]
          Length = 555

 Score = 29.6 bits (65), Expect = 1.3
 Identities = 20/53 (37%), Positives = 24/53 (45%), Gaps = 6/53 (11%)

Query: 50  GPVWGTLYSAMGYGSYLVWKELGGFTEKAVVPLGLYTGQLALNWAWPPIFFGA 102
           G ++ T    MG G   V   LGG T   V  LG Y+  L      PP+ FGA
Sbjct: 448 GELYPTEIRQMGMGFASVHARLGGLTAPLVTTLGEYSTIL------PPVSFGA 494


>gi|239757095 PREDICTED: similar to hCG2005276 [Homo sapiens]
          Length = 261

 Score = 28.9 bits (63), Expect = 2.2
 Identities = 36/128 (28%), Positives = 46/128 (35%), Gaps = 15/128 (11%)

Query: 14  APSLGCFVGSRFVHGEGLRWYAGLQKPSWHPPHWVLGPVWGTLYSAMGYGSYLVWKELGG 73
           AP     +G R +   G RW A   +P+   PHW  GP      +A       +W  LG 
Sbjct: 89  APGQALSMGLRSMQ-VGARW-AQANEPTRRSPHWAAGPGGHQGLAAESTRGRRLW--LGT 144

Query: 74  FTEKAVVPLGLYTGQLALNWA------WPPIFFGARQMGWALVDLLLVSGAAAATTVAWY 127
              +     GL +  L   WA      W P           L   LL    A+A   +W 
Sbjct: 145 CPRQGTG--GLRSRSLRRPWARSSLESWAP---RGASGSLTLSQWLLAPLGASAPPQSWV 199

Query: 128 QVSPLAAR 135
            VSPL  R
Sbjct: 200 PVSPLNRR 207


>gi|239751601 PREDICTED: hypothetical protein XP_002347933 [Homo
           sapiens]
          Length = 282

 Score = 28.9 bits (63), Expect = 2.2
 Identities = 36/128 (28%), Positives = 46/128 (35%), Gaps = 15/128 (11%)

Query: 14  APSLGCFVGSRFVHGEGLRWYAGLQKPSWHPPHWVLGPVWGTLYSAMGYGSYLVWKELGG 73
           AP     +G R +   G RW A   +P+   PHW  GP      +A       +W  LG 
Sbjct: 110 APGQALSMGLRSMQ-VGARW-AQANEPTRRSPHWAAGPGGHQGLAAESTRGRRLW--LGT 165

Query: 74  FTEKAVVPLGLYTGQLALNWA------WPPIFFGARQMGWALVDLLLVSGAAAATTVAWY 127
              +     GL +  L   WA      W P           L   LL    A+A   +W 
Sbjct: 166 CPRQGTG--GLRSRSLRRPWARSSLESWAP---RGASGSLTLSQWLLAPLGASAPPQSWV 220

Query: 128 QVSPLAAR 135
            VSPL  R
Sbjct: 221 PVSPLNRR 228


>gi|239746116 PREDICTED: hypothetical protein XP_002344200 [Homo
           sapiens]
          Length = 282

 Score = 28.9 bits (63), Expect = 2.2
 Identities = 36/128 (28%), Positives = 46/128 (35%), Gaps = 15/128 (11%)

Query: 14  APSLGCFVGSRFVHGEGLRWYAGLQKPSWHPPHWVLGPVWGTLYSAMGYGSYLVWKELGG 73
           AP     +G R +   G RW A   +P+   PHW  GP      +A       +W  LG 
Sbjct: 110 APGQALSMGLRSMQ-VGARW-AQANEPTRRSPHWAAGPGGHQGLAAESTRGRRLW--LGT 165

Query: 74  FTEKAVVPLGLYTGQLALNWA------WPPIFFGARQMGWALVDLLLVSGAAAATTVAWY 127
              +     GL +  L   WA      W P           L   LL    A+A   +W 
Sbjct: 166 CPRQGTG--GLRSRSLRRPWARSSLESWAP---RGASGSLTLSQWLLAPLGASAPPQSWV 220

Query: 128 QVSPLAAR 135
            VSPL  R
Sbjct: 221 PVSPLNRR 228


>gi|223890219 RNA binding motif protein, X-linked-like 3 [Homo
           sapiens]
          Length = 1067

 Score = 28.5 bits (62), Expect = 2.9
 Identities = 17/46 (36%), Positives = 23/46 (50%), Gaps = 1/46 (2%)

Query: 2   APPWVPAMGFTLAPSLGCFVGSRFVHGEGLRWYAGLQKPSW-HPPH 46
           +PP   A   +LA S+GC +  +     G   Y+GLQ   W  PPH
Sbjct: 159 SPPHKRATPSSLAHSVGCGMRGKAPTVSGQDGYSGLQPRRWAGPPH 204


>gi|195539343 elongation of very long chain fatty acids-like 6 [Homo
           sapiens]
          Length = 265

 Score = 28.1 bits (61), Expect = 3.8
 Identities = 14/60 (23%), Positives = 31/60 (51%)

Query: 47  WVLGPVWGTLYSAMGYGSYLVWKELGGFTEKAVVPLGLYTGQLALNWAWPPIFFGARQMG 106
           W L     +++ A+  G+Y+V+  +    +++V   G Y G ++  WA+  +   A ++G
Sbjct: 66  WSLTLAVFSIFGALRTGAYMVYILMTKGLKQSVCDQGFYNGPVSKFWAYAFVLSKAPELG 125


>gi|13129088 elongation of very long chain fatty acids-like 6 [Homo
           sapiens]
          Length = 265

 Score = 28.1 bits (61), Expect = 3.8
 Identities = 14/60 (23%), Positives = 31/60 (51%)

Query: 47  WVLGPVWGTLYSAMGYGSYLVWKELGGFTEKAVVPLGLYTGQLALNWAWPPIFFGARQMG 106
           W L     +++ A+  G+Y+V+  +    +++V   G Y G ++  WA+  +   A ++G
Sbjct: 66  WSLTLAVFSIFGALRTGAYMVYILMTKGLKQSVCDQGFYNGPVSKFWAYAFVLSKAPELG 125


>gi|197927448 WD repeat domain 6 protein [Homo sapiens]
          Length = 1151

 Score = 28.1 bits (61), Expect = 3.8
 Identities = 25/103 (24%), Positives = 45/103 (43%), Gaps = 18/103 (17%)

Query: 33  WYAGLQKPSWHPPHWVLGPVW--GTLYSAMGYGSYLVWKELGGFTEKAVVPLGLYTGQLA 90
           W +GL    W+   W+    W  G +  A+G+ S +++  + G   + V      T +  
Sbjct: 138 WRSGL----WNMSDWIWDARWLEGNIALALGHNSVVLYDPVVGCILQEVP----CTDRCT 189

Query: 91  LNWAWPPIFFGARQMGWALVDLLLVSGAAAATTVAWYQVSPLA 133
           L+         A  +G A  +L +V+GA +   + WY  + LA
Sbjct: 190 LS--------SACLIGDAWKELTIVAGAVSNQLLVWYPATALA 224


>gi|14249552 disrupted in renal carcinoma 2 [Homo sapiens]
          Length = 478

 Score = 28.1 bits (61), Expect = 3.8
 Identities = 29/97 (29%), Positives = 36/97 (37%), Gaps = 11/97 (11%)

Query: 7   PAMGFTLAPSLGCFVGSRFVHGEGLRWYAGLQKPSWHP-PHWVLGPVWGTL--YSAMGYG 63
           P +G  L P LG    SR      L        P+  P P  V G  W  L  +S + + 
Sbjct: 13  PLLGPGLGPGLGASWRSREAAAAAL--------PAAVPGPGRVYGRRWLVLLLFSLLAFV 64

Query: 64  SYLVWKELGGFTEKAVVPLGLYTGQLALNWAWPPIFF 100
             LVW   G     A    G  +  +AL   W PI F
Sbjct: 65  QGLVWNTWGPIQNSARQAYGFSSWDIALLVLWGPIGF 101


>gi|22027554 voltage-dependent calcium channel gamma-6 subunit
           isoform a [Homo sapiens]
          Length = 260

 Score = 28.1 bits (61), Expect = 3.8
 Identities = 18/60 (30%), Positives = 26/60 (43%), Gaps = 9/60 (15%)

Query: 3   PPWVPAMGFTLAPSLGCFVGSRFVHGEGLRWYAGLQKPSWHPPHWVLGPVWGTLYSAMGY 62
           PP  P + +  + SLGC VG+  +   G   +  L  PSW          WG+L    G+
Sbjct: 207 PPPAPRLTYEYSWSLGCGVGAGLILLLGAGCFLLLTLPSW---------PWGSLCPKRGH 257


>gi|22027560 voltage-dependent calcium channel gamma-6 subunit
           isoform c [Homo sapiens]
          Length = 189

 Score = 28.1 bits (61), Expect = 3.8
 Identities = 18/60 (30%), Positives = 26/60 (43%), Gaps = 9/60 (15%)

Query: 3   PPWVPAMGFTLAPSLGCFVGSRFVHGEGLRWYAGLQKPSWHPPHWVLGPVWGTLYSAMGY 62
           PP  P + +  + SLGC VG+  +   G   +  L  PSW          WG+L    G+
Sbjct: 136 PPPAPRLTYEYSWSLGCGVGAGLILLLGAGCFLLLTLPSW---------PWGSLCPKRGH 186


>gi|22027557 voltage-dependent calcium channel gamma-6 subunit
           isoform b [Homo sapiens]
          Length = 214

 Score = 28.1 bits (61), Expect = 3.8
 Identities = 18/60 (30%), Positives = 26/60 (43%), Gaps = 9/60 (15%)

Query: 3   PPWVPAMGFTLAPSLGCFVGSRFVHGEGLRWYAGLQKPSWHPPHWVLGPVWGTLYSAMGY 62
           PP  P + +  + SLGC VG+  +   G   +  L  PSW          WG+L    G+
Sbjct: 161 PPPAPRLTYEYSWSLGCGVGAGLILLLGAGCFLLLTLPSW---------PWGSLCPKRGH 211


>gi|4826645 aquaporin 3 [Homo sapiens]
          Length = 292

 Score = 27.7 bits (60), Expect = 4.9
 Identities = 11/25 (44%), Positives = 16/25 (64%)

Query: 4   PWVPAMGFTLAPSLGCFVGSRFVHG 28
           PW+    +TLA +LG F+G+  V G
Sbjct: 97  PWIKLPIYTLAQTLGAFLGAGIVFG 121


>gi|9256602 protocadherin beta 10 precursor [Homo sapiens]
          Length = 800

 Score = 27.7 bits (60), Expect = 4.9
 Identities = 15/40 (37%), Positives = 19/40 (47%), Gaps = 2/40 (5%)

Query: 53 WGTLYSAMGYGSYLVWKEL--GGFTEKAVVPLGLYTGQLA 90
          WG   +  G+G Y V +E   G F       LGL  G+LA
Sbjct: 21 WGVSLAGSGFGRYSVTEETEKGSFVVNLAKDLGLAEGELA 60


>gi|14195616 protocadherin beta 9 precursor [Homo sapiens]
          Length = 797

 Score = 27.7 bits (60), Expect = 4.9
 Identities = 15/40 (37%), Positives = 19/40 (47%), Gaps = 2/40 (5%)

Query: 53 WGTLYSAMGYGSYLVWKEL--GGFTEKAVVPLGLYTGQLA 90
          WG   +  G+G Y V +E   G F       LGL  G+LA
Sbjct: 21 WGVSLAGSGFGRYSVTEETEKGSFVVNLAKDLGLAEGELA 60


>gi|21389403 folliculin isoform 2 [Homo sapiens]
          Length = 342

 Score = 27.3 bits (59), Expect = 6.4
 Identities = 12/47 (25%), Positives = 19/47 (40%)

Query: 97  PIFFGARQMGWALVDLLLVSGAAAATTVAWYQVSPLAARLLYPYLAW 143
           PIFFG  Q G+       +  + A     WY +  +    +Y   +W
Sbjct: 140 PIFFGDEQHGFVFSHTFFIKDSLARGFQRWYSIITIMMDRIYLINSW 186


>gi|22907034 folliculin isoform 1 [Homo sapiens]
          Length = 579

 Score = 27.3 bits (59), Expect = 6.4
 Identities = 12/47 (25%), Positives = 19/47 (40%)

Query: 97  PIFFGARQMGWALVDLLLVSGAAAATTVAWYQVSPLAARLLYPYLAW 143
           PIFFG  Q G+       +  + A     WY +  +    +Y   +W
Sbjct: 140 PIFFGDEQHGFVFSHTFFIKDSLARGFQRWYSIITIMMDRIYLINSW 186


>gi|157739945 tetratricopeptide repeat, ankyrin repeat and coiled-coil
            containing 2 [Homo sapiens]
          Length = 1990

 Score = 27.3 bits (59), Expect = 6.4
 Identities = 12/22 (54%), Positives = 14/22 (63%)

Query: 97   PIFFGARQMGWALVDLLLVSGA 118
            P+F   RQ  W +VDLLL  GA
Sbjct: 1070 PLFSTVRQGHWQIVDLLLTHGA 1091


>gi|225543463 tetratricopeptide repeat, ankyrin repeat and coiled-coil
            containing 1 isoform 2 [Homo sapiens]
          Length = 1390

 Score = 26.9 bits (58), Expect = 8.4
 Identities = 12/22 (54%), Positives = 14/22 (63%)

Query: 96   PPIFFGARQMGWALVDLLLVSG 117
            PP+F  ARQ  W +V LLL  G
Sbjct: 1106 PPLFCAARQGHWQIVRLLLERG 1127


>gi|225543461 tetratricopeptide repeat, ankyrin repeat and coiled-coil
            containing 1 isoform 1 [Homo sapiens]
          Length = 1861

 Score = 26.9 bits (58), Expect = 8.4
 Identities = 12/22 (54%), Positives = 14/22 (63%)

Query: 96   PPIFFGARQMGWALVDLLLVSG 117
            PP+F  ARQ  W +V LLL  G
Sbjct: 1114 PPLFCAARQGHWQIVRLLLERG 1135


>gi|239747360 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 160

 Score = 26.9 bits (58), Expect = 8.4
 Identities = 11/42 (26%), Positives = 18/42 (42%), Gaps = 10/42 (23%)

Query: 37  LQKPSWHPPHWV----------LGPVWGTLYSAMGYGSYLVW 68
           L +P W PP W+           G  W +  + +  G++L W
Sbjct: 110 LSEPPWRPPKWLWQSCRGGGNKKGDTWLSFLNQLTMGTHLYW 151


>gi|239741185 PREDICTED: hypothetical protein XP_002342152 [Homo
           sapiens]
          Length = 160

 Score = 26.9 bits (58), Expect = 8.4
 Identities = 11/42 (26%), Positives = 18/42 (42%), Gaps = 10/42 (23%)

Query: 37  LQKPSWHPPHWV----------LGPVWGTLYSAMGYGSYLVW 68
           L +P W PP W+           G  W +  + +  G++L W
Sbjct: 110 LSEPPWRPPKWLWQSCRGGGNKKGDTWLSFLNQLTMGTHLYW 151


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.325    0.141    0.519 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 7,467,649
Number of Sequences: 37866
Number of extensions: 319698
Number of successful extensions: 799
Number of sequences better than 10.0: 25
Number of HSP's better than 10.0 without gapping: 14
Number of HSP's successfully gapped in prelim test: 11
Number of HSP's that attempted gapping in prelim test: 783
Number of HSP's gapped (non-prelim): 25
length of query: 169
length of database: 18,247,518
effective HSP length: 95
effective length of query: 74
effective length of database: 14,650,248
effective search space: 1084118352
effective search space used: 1084118352
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.6 bits)
S2: 58 (26.9 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
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