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Search of human proteins with 74024895
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|74024895 mitochondrial translation optimization 1 homolog
isoform a [Homo sapiens]
(692 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|74024895 mitochondrial translation optimization 1 homolog iso... 1382 0.0
gi|19882217 mitochondrial translation optimization 1 homolog iso... 1368 0.0
gi|183227703 mitochondrial translation optimization 1 homolog is... 1363 0.0
gi|148277071 thioredoxin reductase 1 isoform 3 [Homo sapiens] 35 0.18
gi|148277065 thioredoxin reductase 1 isoform 1 [Homo sapiens] 35 0.18
gi|5454102 transforming, acidic coiled-coil containing protein 3... 35 0.23
gi|33519426 thioredoxin reductase 1 isoform 2 [Homo sapiens] 34 0.52
gi|33519430 thioredoxin reductase 1 isoform 2 [Homo sapiens] 34 0.52
gi|33519428 thioredoxin reductase 1 isoform 2 [Homo sapiens] 34 0.52
gi|229577391 pyridine nucleotide-disulphide oxidoreductase domai... 33 0.89
gi|23943928 hypothetical protein LOC140680 [Homo sapiens] 33 1.2
gi|30581135 structural maintenance of chromosomes 1A [Homo sapiens] 32 1.5
gi|203098013 all-trans-13,14-dihydroretinol saturase [Homo sapiens] 32 1.5
gi|8923708 FAD-dependent oxidoreductase domain containing 1 [Hom... 32 2.0
gi|119943098 dihydropyrimidine dehydrogenase isoform 1 [Homo sap... 32 2.6
gi|133908616 glycerol-3-phosphate dehydrogenase 2, mitochondrial... 31 3.4
gi|133908614 glycerol-3-phosphate dehydrogenase 2, mitochondrial... 31 3.4
gi|62543567 nudix (nucleoside diphosphate linked moiety X)-type ... 31 3.4
gi|148839466 kalirin, RhoGEF kinase isoform 1 [Homo sapiens] 31 4.4
gi|68362740 kalirin, RhoGEF kinase isoform 3 [Homo sapiens] 31 4.4
gi|119709832 low density lipoprotein receptor-related protein 5 ... 31 4.4
gi|156416003 succinate dehydrogenase complex, subunit A, flavopr... 31 4.4
gi|4504383 HGF activator preproprotein [Homo sapiens] 31 4.4
gi|4557735 monoamine oxidase A [Homo sapiens] 30 5.7
gi|50301238 glutathione reductase [Homo sapiens] 30 5.7
gi|198442844 dynein, axonemal, heavy chain 10 [Homo sapiens] 30 7.5
gi|19923899 coiled-coil domain containing 45 [Homo sapiens] 30 7.5
gi|51477723 testis expressed sequence 11 isoform 2 [Homo sapiens] 30 9.8
gi|51477721 testis expressed sequence 11 isoform 1 [Homo sapiens] 30 9.8
gi|114155142 nuclear pore complex-associated protein TPR [Homo s... 30 9.8
>gi|74024895 mitochondrial translation optimization 1 homolog
isoform a [Homo sapiens]
Length = 692
Score = 1382 bits (3578), Expect = 0.0
Identities = 692/692 (100%), Positives = 692/692 (100%)
Query: 1 MFYFRGCGRWVAVSFTKQQFPLARLSSDSAAPRTPHFDVIVIGGGHAGTEAATAAARCGS 60
MFYFRGCGRWVAVSFTKQQFPLARLSSDSAAPRTPHFDVIVIGGGHAGTEAATAAARCGS
Sbjct: 1 MFYFRGCGRWVAVSFTKQQFPLARLSSDSAAPRTPHFDVIVIGGGHAGTEAATAAARCGS 60
Query: 61 RTLLLTHRVDTIGQMSCNPSFGGIGKGHLMREVDALDGLCSRICDQSGVHYKVLNRRKGP 120
RTLLLTHRVDTIGQMSCNPSFGGIGKGHLMREVDALDGLCSRICDQSGVHYKVLNRRKGP
Sbjct: 61 RTLLLTHRVDTIGQMSCNPSFGGIGKGHLMREVDALDGLCSRICDQSGVHYKVLNRRKGP 120
Query: 121 AVWGLRAQIDRKLYKQNMQKEILNTPLLTVQEGAVEDLILTEPEPEHTGKCRVSGVVLVD 180
AVWGLRAQIDRKLYKQNMQKEILNTPLLTVQEGAVEDLILTEPEPEHTGKCRVSGVVLVD
Sbjct: 121 AVWGLRAQIDRKLYKQNMQKEILNTPLLTVQEGAVEDLILTEPEPEHTGKCRVSGVVLVD 180
Query: 181 GSTVYAESVILTTGTFLRGMIVIGLETHPAGRLGDQPSIGLAQTLEKLGFVVGRLKTGTP 240
GSTVYAESVILTTGTFLRGMIVIGLETHPAGRLGDQPSIGLAQTLEKLGFVVGRLKTGTP
Sbjct: 181 GSTVYAESVILTTGTFLRGMIVIGLETHPAGRLGDQPSIGLAQTLEKLGFVVGRLKTGTP 240
Query: 241 PRIAKESINFSILNKHIPDNPSIPFSFTNETVWIKPEDQLPCYLTHTNPRVDEIVLKNLH 300
PRIAKESINFSILNKHIPDNPSIPFSFTNETVWIKPEDQLPCYLTHTNPRVDEIVLKNLH
Sbjct: 241 PRIAKESINFSILNKHIPDNPSIPFSFTNETVWIKPEDQLPCYLTHTNPRVDEIVLKNLH 300
Query: 301 LNSHVKETTRGPRYCPSIESKVLRFPNRLHQVWLEPEGMDSDLIYPQGLSMTLPAELQEK 360
LNSHVKETTRGPRYCPSIESKVLRFPNRLHQVWLEPEGMDSDLIYPQGLSMTLPAELQEK
Sbjct: 301 LNSHVKETTRGPRYCPSIESKVLRFPNRLHQVWLEPEGMDSDLIYPQGLSMTLPAELQEK 360
Query: 361 MITCIRGLEKAKVIQPGYGVQYDYLDPRQITPSLETHLVQRLFFAGQINGTTGYEEAAAQ 420
MITCIRGLEKAKVIQPGYGVQYDYLDPRQITPSLETHLVQRLFFAGQINGTTGYEEAAAQ
Sbjct: 361 MITCIRGLEKAKVIQPGYGVQYDYLDPRQITPSLETHLVQRLFFAGQINGTTGYEEAAAQ 420
Query: 421 GVIAGINASLRVSRKPPFVVSRTEGYIGVLIDDLTTLGTSEPYRMFTSRVEFRLSLRPDN 480
GVIAGINASLRVSRKPPFVVSRTEGYIGVLIDDLTTLGTSEPYRMFTSRVEFRLSLRPDN
Sbjct: 421 GVIAGINASLRVSRKPPFVVSRTEGYIGVLIDDLTTLGTSEPYRMFTSRVEFRLSLRPDN 480
Query: 481 ADSRLTLRGYKDAGCVSQQRYERACWMKSSLEEGISVLKSIEFLSSKWKKLIPEASISTS 540
ADSRLTLRGYKDAGCVSQQRYERACWMKSSLEEGISVLKSIEFLSSKWKKLIPEASISTS
Sbjct: 481 ADSRLTLRGYKDAGCVSQQRYERACWMKSSLEEGISVLKSIEFLSSKWKKLIPEASISTS 540
Query: 541 RSLPVRALDVLKYEEVDMDSLAKAVPEPLKKYTKCRELAERLKIEATYESVLFHQLQEIK 600
RSLPVRALDVLKYEEVDMDSLAKAVPEPLKKYTKCRELAERLKIEATYESVLFHQLQEIK
Sbjct: 541 RSLPVRALDVLKYEEVDMDSLAKAVPEPLKKYTKCRELAERLKIEATYESVLFHQLQEIK 600
Query: 601 GVQQDEALQLPKDLDYLTIRDVSLSHEVREKLHFSRPQTIGAASRIPGVTPAAIINLLRF 660
GVQQDEALQLPKDLDYLTIRDVSLSHEVREKLHFSRPQTIGAASRIPGVTPAAIINLLRF
Sbjct: 601 GVQQDEALQLPKDLDYLTIRDVSLSHEVREKLHFSRPQTIGAASRIPGVTPAAIINLLRF 660
Query: 661 VKTTQRRQSAMNESSKTDQYLCDADRLQEREL 692
VKTTQRRQSAMNESSKTDQYLCDADRLQEREL
Sbjct: 661 VKTTQRRQSAMNESSKTDQYLCDADRLQEREL 692
>gi|19882217 mitochondrial translation optimization 1 homolog
isoform b [Homo sapiens]
Length = 717
Score = 1368 bits (3542), Expect = 0.0
Identities = 692/717 (96%), Positives = 692/717 (96%), Gaps = 25/717 (3%)
Query: 1 MFYFRGCGRWVAVSFTKQQFPLARLSSDSAAPRTPHFDVIVIGGGHAGTEAATAAARCGS 60
MFYFRGCGRWVAVSFTKQQFPLARLSSDSAAPRTPHFDVIVIGGGHAGTEAATAAARCGS
Sbjct: 1 MFYFRGCGRWVAVSFTKQQFPLARLSSDSAAPRTPHFDVIVIGGGHAGTEAATAAARCGS 60
Query: 61 RTLLLTHRVDTIGQMSCNPSFGGIGKGHLMREVDALDGLCSRICDQSGVHYKVLNRRKGP 120
RTLLLTHRVDTIGQMSCNPSFGGIGKGHLMREVDALDGLCSRICDQSGVHYKVLNRRKGP
Sbjct: 61 RTLLLTHRVDTIGQMSCNPSFGGIGKGHLMREVDALDGLCSRICDQSGVHYKVLNRRKGP 120
Query: 121 AVWGLRAQIDRKLYKQNMQKEILNTPLLTVQEGAVEDLILTEPEPEHTGKCRVSGVVLVD 180
AVWGLRAQIDRKLYKQNMQKEILNTPLLTVQEGAVEDLILTEPEPEHTGKCRVSGVVLVD
Sbjct: 121 AVWGLRAQIDRKLYKQNMQKEILNTPLLTVQEGAVEDLILTEPEPEHTGKCRVSGVVLVD 180
Query: 181 GSTVYAESVILTTGTFLRGMIVIGLETHPAGRLGDQPSIGLAQTLEKLGFVVGRLKTGTP 240
GSTVYAESVILTTGTFLRGMIVIGLETHPAGRLGDQPSIGLAQTLEKLGFVVGRLKTGTP
Sbjct: 181 GSTVYAESVILTTGTFLRGMIVIGLETHPAGRLGDQPSIGLAQTLEKLGFVVGRLKTGTP 240
Query: 241 PRIAKESINFSILNKHIPDNPSIPFSFTNETVWIKPEDQLPCYLTHTNPRVDEIVLKNLH 300
PRIAKESINFSILNKHIPDNPSIPFSFTNETVWIKPEDQLPCYLTHTNPRVDEIVLKNLH
Sbjct: 241 PRIAKESINFSILNKHIPDNPSIPFSFTNETVWIKPEDQLPCYLTHTNPRVDEIVLKNLH 300
Query: 301 LNSHVKETTRGPRYCPSIESKVLRFPNRLHQVWLEPEGMDSDLIYPQGLSMTLPAELQEK 360
LNSHVKETTRGPRYCPSIESKVLRFPNRLHQVWLEPEGMDSDLIYPQGLSMTLPAELQEK
Sbjct: 301 LNSHVKETTRGPRYCPSIESKVLRFPNRLHQVWLEPEGMDSDLIYPQGLSMTLPAELQEK 360
Query: 361 MITCIRGLEKAKVIQ-------------------------PGYGVQYDYLDPRQITPSLE 395
MITCIRGLEKAKVIQ PGYGVQYDYLDPRQITPSLE
Sbjct: 361 MITCIRGLEKAKVIQPDGVLLLLPRMECNGAISAHHNLPLPGYGVQYDYLDPRQITPSLE 420
Query: 396 THLVQRLFFAGQINGTTGYEEAAAQGVIAGINASLRVSRKPPFVVSRTEGYIGVLIDDLT 455
THLVQRLFFAGQINGTTGYEEAAAQGVIAGINASLRVSRKPPFVVSRTEGYIGVLIDDLT
Sbjct: 421 THLVQRLFFAGQINGTTGYEEAAAQGVIAGINASLRVSRKPPFVVSRTEGYIGVLIDDLT 480
Query: 456 TLGTSEPYRMFTSRVEFRLSLRPDNADSRLTLRGYKDAGCVSQQRYERACWMKSSLEEGI 515
TLGTSEPYRMFTSRVEFRLSLRPDNADSRLTLRGYKDAGCVSQQRYERACWMKSSLEEGI
Sbjct: 481 TLGTSEPYRMFTSRVEFRLSLRPDNADSRLTLRGYKDAGCVSQQRYERACWMKSSLEEGI 540
Query: 516 SVLKSIEFLSSKWKKLIPEASISTSRSLPVRALDVLKYEEVDMDSLAKAVPEPLKKYTKC 575
SVLKSIEFLSSKWKKLIPEASISTSRSLPVRALDVLKYEEVDMDSLAKAVPEPLKKYTKC
Sbjct: 541 SVLKSIEFLSSKWKKLIPEASISTSRSLPVRALDVLKYEEVDMDSLAKAVPEPLKKYTKC 600
Query: 576 RELAERLKIEATYESVLFHQLQEIKGVQQDEALQLPKDLDYLTIRDVSLSHEVREKLHFS 635
RELAERLKIEATYESVLFHQLQEIKGVQQDEALQLPKDLDYLTIRDVSLSHEVREKLHFS
Sbjct: 601 RELAERLKIEATYESVLFHQLQEIKGVQQDEALQLPKDLDYLTIRDVSLSHEVREKLHFS 660
Query: 636 RPQTIGAASRIPGVTPAAIINLLRFVKTTQRRQSAMNESSKTDQYLCDADRLQEREL 692
RPQTIGAASRIPGVTPAAIINLLRFVKTTQRRQSAMNESSKTDQYLCDADRLQEREL
Sbjct: 661 RPQTIGAASRIPGVTPAAIINLLRFVKTTQRRQSAMNESSKTDQYLCDADRLQEREL 717
>gi|183227703 mitochondrial translation optimization 1 homolog
isoform c [Homo sapiens]
Length = 732
Score = 1363 bits (3527), Expect = 0.0
Identities = 692/732 (94%), Positives = 692/732 (94%), Gaps = 40/732 (5%)
Query: 1 MFYFRGCGRWVAVSFTKQQFPLARLSSDSAAPRTPHFDVIVIGGGHAGTEAATAAARCGS 60
MFYFRGCGRWVAVSFTKQQFPLARLSSDSAAPRTPHFDVIVIGGGHAGTEAATAAARCGS
Sbjct: 1 MFYFRGCGRWVAVSFTKQQFPLARLSSDSAAPRTPHFDVIVIGGGHAGTEAATAAARCGS 60
Query: 61 RTLLLTHRVDTIGQMSCNPSFGGIGKGHLMREVDALDGLCSRICDQSGVHYKVLNRRKGP 120
RTLLLTHRVDTIGQMSCNPSFGGIGKGHLMREVDALDGLCSRICDQSGVHYKVLNRRKGP
Sbjct: 61 RTLLLTHRVDTIGQMSCNPSFGGIGKGHLMREVDALDGLCSRICDQSGVHYKVLNRRKGP 120
Query: 121 AVWGLRAQIDRKLYKQNMQKEILNTPLLTVQEGAVEDLILTEPEPEHTGKCRVSGVVLVD 180
AVWGLRAQIDRKLYKQNMQKEILNTPLLTVQEGAVEDLILTEPEPEHTGKCRVSGVVLVD
Sbjct: 121 AVWGLRAQIDRKLYKQNMQKEILNTPLLTVQEGAVEDLILTEPEPEHTGKCRVSGVVLVD 180
Query: 181 GSTVYAESVILTTGTFLRGMIVIGLETHPAGRLGDQPSIGLAQTLEKLGFVVGRLKTGTP 240
GSTVYAESVILTTGTFLRGMIVIGLETHPAGRLGDQPSIGLAQTLEKLGFVVGRLKTGTP
Sbjct: 181 GSTVYAESVILTTGTFLRGMIVIGLETHPAGRLGDQPSIGLAQTLEKLGFVVGRLKTGTP 240
Query: 241 PRIAKESINFSILNKHIPDNPSIPFSFTNETVWIKPEDQLPCYLTHTNPRVDEIVLKNLH 300
PRIAKESINFSILNKHIPDNPSIPFSFTNETVWIKPEDQLPCYLTHTNPRVDEIVLKNLH
Sbjct: 241 PRIAKESINFSILNKHIPDNPSIPFSFTNETVWIKPEDQLPCYLTHTNPRVDEIVLKNLH 300
Query: 301 LNSHVKETTRGPRYCPSIESKVLRFPNRLHQVWLEPEGMDSDLIYPQGLSMTLPAELQEK 360
LNSHVKETTRGPRYCPSIESKVLRFPNRLHQVWLEPEGMDSDLIYPQGLSMTLPAELQEK
Sbjct: 301 LNSHVKETTRGPRYCPSIESKVLRFPNRLHQVWLEPEGMDSDLIYPQGLSMTLPAELQEK 360
Query: 361 MITCIRGLEKAKVIQPGYGVQYDYLDPRQITPSLETHLVQRLFFAGQINGTTGYEEAAA- 419
MITCIRGLEKAKVIQPGYGVQYDYLDPRQITPSLETHLVQRLFFAGQINGTTGYEEAAA
Sbjct: 361 MITCIRGLEKAKVIQPGYGVQYDYLDPRQITPSLETHLVQRLFFAGQINGTTGYEEAAAQ 420
Query: 420 ---------------------------------------QGVIAGINASLRVSRKPPFVV 440
QGVIAGINASLRVSRKPPFVV
Sbjct: 421 TECCSVARLECSDMISQLQAILLPQPSLVAGTAGMHHNTQGVIAGINASLRVSRKPPFVV 480
Query: 441 SRTEGYIGVLIDDLTTLGTSEPYRMFTSRVEFRLSLRPDNADSRLTLRGYKDAGCVSQQR 500
SRTEGYIGVLIDDLTTLGTSEPYRMFTSRVEFRLSLRPDNADSRLTLRGYKDAGCVSQQR
Sbjct: 481 SRTEGYIGVLIDDLTTLGTSEPYRMFTSRVEFRLSLRPDNADSRLTLRGYKDAGCVSQQR 540
Query: 501 YERACWMKSSLEEGISVLKSIEFLSSKWKKLIPEASISTSRSLPVRALDVLKYEEVDMDS 560
YERACWMKSSLEEGISVLKSIEFLSSKWKKLIPEASISTSRSLPVRALDVLKYEEVDMDS
Sbjct: 541 YERACWMKSSLEEGISVLKSIEFLSSKWKKLIPEASISTSRSLPVRALDVLKYEEVDMDS 600
Query: 561 LAKAVPEPLKKYTKCRELAERLKIEATYESVLFHQLQEIKGVQQDEALQLPKDLDYLTIR 620
LAKAVPEPLKKYTKCRELAERLKIEATYESVLFHQLQEIKGVQQDEALQLPKDLDYLTIR
Sbjct: 601 LAKAVPEPLKKYTKCRELAERLKIEATYESVLFHQLQEIKGVQQDEALQLPKDLDYLTIR 660
Query: 621 DVSLSHEVREKLHFSRPQTIGAASRIPGVTPAAIINLLRFVKTTQRRQSAMNESSKTDQY 680
DVSLSHEVREKLHFSRPQTIGAASRIPGVTPAAIINLLRFVKTTQRRQSAMNESSKTDQY
Sbjct: 661 DVSLSHEVREKLHFSRPQTIGAASRIPGVTPAAIINLLRFVKTTQRRQSAMNESSKTDQY 720
Query: 681 LCDADRLQEREL 692
LCDADRLQEREL
Sbjct: 721 LCDADRLQEREL 732
>gi|148277071 thioredoxin reductase 1 isoform 3 [Homo sapiens]
Length = 649
Score = 35.4 bits (80), Expect = 0.18
Identities = 15/44 (34%), Positives = 27/44 (61%)
Query: 22 LARLSSDSAAPRTPHFDVIVIGGGHAGTEAATAAARCGSRTLLL 65
L +++ P++ +D+I+IGGG G AA AA+ G + ++L
Sbjct: 148 LLKMNGPEDLPKSYDYDLIIIGGGSGGLAAAKEAAQYGKKVMVL 191
>gi|148277065 thioredoxin reductase 1 isoform 1 [Homo sapiens]
Length = 551
Score = 35.4 bits (80), Expect = 0.18
Identities = 15/44 (34%), Positives = 27/44 (61%)
Query: 22 LARLSSDSAAPRTPHFDVIVIGGGHAGTEAATAAARCGSRTLLL 65
L +++ P++ +D+I+IGGG G AA AA+ G + ++L
Sbjct: 50 LLKMNGPEDLPKSYDYDLIIIGGGSGGLAAAKEAAQYGKKVMVL 93
>gi|5454102 transforming, acidic coiled-coil containing protein 3
[Homo sapiens]
Length = 838
Score = 35.0 bits (79), Expect = 0.23
Identities = 23/79 (29%), Positives = 45/79 (56%), Gaps = 8/79 (10%)
Query: 548 LDVLKYEEVDMDSLAKAVPEPLKKY-TKCREL----AERLKIEATYESVLFHQLQEI--- 599
+D+L+Y + D+D++ KA E ++ ++C EL E KI +E V++ ++E+
Sbjct: 634 VDLLQYSQKDLDAVVKATQEENRELRSRCEELHGKNLELGKIMDRFEEVVYQAMEEVQKQ 693
Query: 600 KGVQQDEALQLPKDLDYLT 618
K + + E ++ K+ D LT
Sbjct: 694 KELSKAEIQKVLKEKDQLT 712
>gi|33519426 thioredoxin reductase 1 isoform 2 [Homo sapiens]
Length = 499
Score = 33.9 bits (76), Expect = 0.52
Identities = 14/34 (41%), Positives = 23/34 (67%)
Query: 32 PRTPHFDVIVIGGGHAGTEAATAAARCGSRTLLL 65
P++ +D+I+IGGG G AA AA+ G + ++L
Sbjct: 8 PKSYDYDLIIIGGGSGGLAAAKEAAQYGKKVMVL 41
>gi|33519430 thioredoxin reductase 1 isoform 2 [Homo sapiens]
Length = 499
Score = 33.9 bits (76), Expect = 0.52
Identities = 14/34 (41%), Positives = 23/34 (67%)
Query: 32 PRTPHFDVIVIGGGHAGTEAATAAARCGSRTLLL 65
P++ +D+I+IGGG G AA AA+ G + ++L
Sbjct: 8 PKSYDYDLIIIGGGSGGLAAAKEAAQYGKKVMVL 41
>gi|33519428 thioredoxin reductase 1 isoform 2 [Homo sapiens]
Length = 499
Score = 33.9 bits (76), Expect = 0.52
Identities = 14/34 (41%), Positives = 23/34 (67%)
Query: 32 PRTPHFDVIVIGGGHAGTEAATAAARCGSRTLLL 65
P++ +D+I+IGGG G AA AA+ G + ++L
Sbjct: 8 PKSYDYDLIIIGGGSGGLAAAKEAAQYGKKVMVL 41
>gi|229577391 pyridine nucleotide-disulphide oxidoreductase domain
2 [Homo sapiens]
Length = 581
Score = 33.1 bits (74), Expect = 0.89
Identities = 20/62 (32%), Positives = 26/62 (41%), Gaps = 1/62 (1%)
Query: 8 GRWVAVSFTKQQFPLARLSSDSA-APRTPHFDVIVIGGGHAGTEAATAAARCGSRTLLLT 66
GR + + FP R + A P +D +VIG GH G AA R G T +
Sbjct: 5 GRGLCKAVAASPFPAWRRDNTEARGGLKPEYDAVVIGAGHNGLVAAAYLQRLGVNTAVFE 64
Query: 67 HR 68
R
Sbjct: 65 RR 66
>gi|23943928 hypothetical protein LOC140680 [Homo sapiens]
Length = 363
Score = 32.7 bits (73), Expect = 1.2
Identities = 41/143 (28%), Positives = 60/143 (41%), Gaps = 43/143 (30%)
Query: 507 MKSSLEEGISVLKSIE----FLSSKWKKLIPEAS-ISTSRSLPVRAL-----------DV 550
MK+SL G + L+ + FLS ++LI + S +L VRAL D+
Sbjct: 101 MKTSLRSGRAALRELRSRENFLSKLNRELIETIQEMENSTTLHVRALLQQQDTLATIIDI 160
Query: 551 LKYEEVDMDSLAKAVPEPLKKYTKCR-----ELAERL--KIEATYESV------------ 591
L+Y K+ + ++ KC+ + AE+L KIE T E V
Sbjct: 161 LEYSNKKRLQQLKSELQEWEEKKKCKMSYLEQQAEQLNAKIEKTQEEVNFLSTYMDHEYS 220
Query: 592 --------LFHQLQEIKGVQQDE 606
L QLQ++K QQDE
Sbjct: 221 IKSVQISTLMRQLQQVKDSQQDE 243
>gi|30581135 structural maintenance of chromosomes 1A [Homo sapiens]
Length = 1233
Score = 32.3 bits (72), Expect = 1.5
Identities = 37/158 (23%), Positives = 77/158 (48%), Gaps = 20/158 (12%)
Query: 497 SQQRYERACWMKSSLEEGISVLKSIEFLSSKWKKLIPEASISTSRSLPVRALDVLKYEEV 556
+Q+ Y++ K ++E + S+E ++++ + E S S R L + V KY +
Sbjct: 322 AQKHYKKR---KGDMDELEKEMLSVEKARQEFEERMEEESQSQGRDLTLEENQVKKYHRL 378
Query: 557 DMDSLAKA--VPEPLKKYTKCR-------ELAERLKIEATYESVLFHQLQEIKGVQQDEA 607
++ +A + + L+K+ + + +L ER K+E E+ + +L+EI+ Q+
Sbjct: 379 KEEASKRAATLAQELEKFNRDQKADQDRLDLEERKKVET--EAKIKQKLREIEENQK--- 433
Query: 608 LQLPKDLDYLTIRDVSLSHEVREKLHFSRPQTIGAASR 645
++ K +Y+T SL E ++KL + + A R
Sbjct: 434 -RIEKLEEYITTSKQSL--EEQKKLEGELTEEVEMAKR 468
>gi|203098013 all-trans-13,14-dihydroretinol saturase [Homo sapiens]
Length = 610
Score = 32.3 bits (72), Expect = 1.5
Identities = 19/48 (39%), Positives = 23/48 (47%), Gaps = 3/48 (6%)
Query: 38 DVIVIGGGHAGTEAATAAARCGSRTLLLTHRVDTIGQMSCNPSFGGIG 85
DV+VIG G G AA A+ G R L+L G C +FG G
Sbjct: 69 DVVVIGSGFGGLAAAAILAKAGKRVLVLEQHTKAGG---CCHTFGKNG 113
>gi|8923708 FAD-dependent oxidoreductase domain containing 1 [Homo
sapiens]
Length = 486
Score = 32.0 bits (71), Expect = 2.0
Identities = 21/64 (32%), Positives = 30/64 (46%), Gaps = 4/64 (6%)
Query: 25 LSSDSAAPRTPHFDVIVIGGGHAGTEAA----TAAARCGSRTLLLTHRVDTIGQMSCNPS 80
L D++ H DV+++GGG G A +R G+ +L+ R T Q S S
Sbjct: 52 LLQDTSHLPPEHSDVVIVGGGVLGLSVAYWLKKLESRRGAIRVLVVERDHTYSQASTGLS 111
Query: 81 FGGI 84
GGI
Sbjct: 112 VGGI 115
>gi|119943098 dihydropyrimidine dehydrogenase isoform 1 [Homo
sapiens]
Length = 1025
Score = 31.6 bits (70), Expect = 2.6
Identities = 13/30 (43%), Positives = 19/30 (63%)
Query: 39 VIVIGGGHAGTEAATAAARCGSRTLLLTHR 68
VIV+G G + AT+A RCG+R + + R
Sbjct: 335 VIVLGAGDTAFDCATSALRCGARRVFIVFR 364
>gi|133908616 glycerol-3-phosphate dehydrogenase 2, mitochondrial
[Homo sapiens]
Length = 727
Score = 31.2 bits (69), Expect = 3.4
Identities = 20/64 (31%), Positives = 30/64 (46%)
Query: 34 TPHFDVIVIGGGHAGTEAATAAARCGSRTLLLTHRVDTIGQMSCNPSFGGIGKGHLMREV 93
T FD++VIGGG G+ A A G +T L+ + G S + G +L + +
Sbjct: 67 TSEFDILVIGGGATGSGCALDAVTRGLKTALVERDDFSSGTSSRSTKLIHGGVRYLQKAI 126
Query: 94 DALD 97
LD
Sbjct: 127 MKLD 130
>gi|133908614 glycerol-3-phosphate dehydrogenase 2, mitochondrial
[Homo sapiens]
Length = 727
Score = 31.2 bits (69), Expect = 3.4
Identities = 20/64 (31%), Positives = 30/64 (46%)
Query: 34 TPHFDVIVIGGGHAGTEAATAAARCGSRTLLLTHRVDTIGQMSCNPSFGGIGKGHLMREV 93
T FD++VIGGG G+ A A G +T L+ + G S + G +L + +
Sbjct: 67 TSEFDILVIGGGATGSGCALDAVTRGLKTALVERDDFSSGTSSRSTKLIHGGVRYLQKAI 126
Query: 94 DALD 97
LD
Sbjct: 127 MKLD 130
>gi|62543567 nudix (nucleoside diphosphate linked moiety X)-type
motif 17 [Homo sapiens]
Length = 328
Score = 31.2 bits (69), Expect = 3.4
Identities = 24/93 (25%), Positives = 42/93 (45%), Gaps = 6/93 (6%)
Query: 18 QQFPLARLSSDSAAPRTPHFDVIVIGGGHAGTEAATAAARCGSRTLLLTHRVDTIGQMSC 77
Q+ P ++ PR P ++ G G ++ +T+LLT R T+ S
Sbjct: 64 QRPPFCPFAALEERPRVPGAELPTDRGVDLGVAVILQSS---DKTVLLTRRARTL---SV 117
Query: 78 NPSFGGIGKGHLMREVDALDGLCSRICDQSGVH 110
+P+ GH+ E + LDG + ++SG+H
Sbjct: 118 SPNLWVPPGGHVELEEELLDGGLRELWEESGLH 150
>gi|148839466 kalirin, RhoGEF kinase isoform 1 [Homo sapiens]
Length = 2986
Score = 30.8 bits (68), Expect = 4.4
Identities = 19/57 (33%), Positives = 29/57 (50%), Gaps = 5/57 (8%)
Query: 144 NTPLLTVQEGAVEDLILTEPEPEHTGKCRVSGVVL---VDGSTVYAESVILTTGTFL 197
N P+ QE + +IL P TG C +SG + +GS ++ +SV T T+L
Sbjct: 2573 NRPI--AQERSCTSVILRWLPPSSTGNCTISGYTVEYREEGSQIWQQSVASTLDTYL 2627
>gi|68362740 kalirin, RhoGEF kinase isoform 3 [Homo sapiens]
Length = 1289
Score = 30.8 bits (68), Expect = 4.4
Identities = 19/57 (33%), Positives = 29/57 (50%), Gaps = 5/57 (8%)
Query: 144 NTPLLTVQEGAVEDLILTEPEPEHTGKCRVSGVVL---VDGSTVYAESVILTTGTFL 197
N P+ QE + +IL P TG C +SG + +GS ++ +SV T T+L
Sbjct: 876 NRPI--AQERSCTSVILRWLPPSSTGNCTISGYTVEYREEGSQIWQQSVASTLDTYL 930
>gi|119709832 low density lipoprotein receptor-related protein 5
[Homo sapiens]
Length = 1615
Score = 30.8 bits (68), Expect = 4.4
Identities = 17/48 (35%), Positives = 26/48 (54%), Gaps = 1/48 (2%)
Query: 450 LIDDLTTLGTSEPYRMFTSRVEF-RLSLRPDNADSRLTLRGYKDAGCV 496
L+ D+ T E + +FTSR R+SL +N D + L G K+A +
Sbjct: 633 LLSDMKTCIVPEAFLVFTSRAAIHRISLETNNNDVAIPLTGVKEASAL 680
>gi|156416003 succinate dehydrogenase complex, subunit A,
flavoprotein precursor [Homo sapiens]
Length = 664
Score = 30.8 bits (68), Expect = 4.4
Identities = 28/98 (28%), Positives = 38/98 (38%), Gaps = 17/98 (17%)
Query: 27 SDSAAPRTP----HFDVIVIGGGHAGTEAATAAARCGSRTLLLTHRVDT-----IGQMSC 77
SDS + + P FD +V+G G AG AA + G T +T T Q
Sbjct: 48 SDSISAQYPVVDHEFDAVVVGAGGAGLRAAFGLSEAGFNTACVTKLFPTRSHTVAAQGGI 107
Query: 78 NPSFGGI----GKGHLMREVDALDGLCSRICDQSGVHY 111
N + G + + H V D L DQ +HY
Sbjct: 108 NAALGNMEEDNWRWHFYDTVKGSDWL----GDQDAIHY 141
>gi|4504383 HGF activator preproprotein [Homo sapiens]
Length = 655
Score = 30.8 bits (68), Expect = 4.4
Identities = 28/107 (26%), Positives = 45/107 (42%), Gaps = 6/107 (5%)
Query: 551 LKYEEVDMDSLAKAVPEPLKKYTKCR--ELAERLKIEATYESVLFHQLQEIKGVQQDEAL 608
L Y+E+ +DS+ A L + CR + ER +S L + ++ + +
Sbjct: 314 LLYQELHVDSVGAAALLGLGPHAYCRNPDNDERPWCYVVKDSALSWEYCRLEACESLTRV 373
Query: 609 QLPKDLDYLTIRDVSLSHEVREKLH----FSRPQTIGAASRIPGVTP 651
QL DL S + + H F RP+ IG +S +PG P
Sbjct: 374 QLSPDLLATLPEPASPGRQACGRRHKKRTFLRPRIIGGSSSLPGSHP 420
>gi|4557735 monoamine oxidase A [Homo sapiens]
Length = 527
Score = 30.4 bits (67), Expect = 5.7
Identities = 17/37 (45%), Positives = 21/37 (56%), Gaps = 1/37 (2%)
Query: 37 FDVIVIGGGHAGTEAATAAARCGSRTLLLTHRVDTIG 73
FDV+VIGGG +G AA G L+L R D +G
Sbjct: 14 FDVVVIGGGISGLSAAKLLTEYGVSVLVLEAR-DRVG 49
>gi|50301238 glutathione reductase [Homo sapiens]
Length = 522
Score = 30.4 bits (67), Expect = 5.7
Identities = 18/52 (34%), Positives = 28/52 (53%), Gaps = 2/52 (3%)
Query: 30 AAPRTPHFDVIVIGGGHAGTEAATAAARCGSRTLLL-THRV-DTIGQMSCNP 79
AA +D +VIGGG G +A AA G+R ++ +H++ T + C P
Sbjct: 58 AAGAVASYDYLVIGGGSGGLASARRAAELGARAAVVESHKLGGTCVNVGCVP 109
>gi|198442844 dynein, axonemal, heavy chain 10 [Homo sapiens]
Length = 4471
Score = 30.0 bits (66), Expect = 7.5
Identities = 37/137 (27%), Positives = 60/137 (43%), Gaps = 18/137 (13%)
Query: 511 LEEGISVLKSIEFLSSKWKKL----IPEASISTSRSL-----PVRALDVLKYEEVDMDSL 561
L EG+ V K E+ + W L + E R+L PVR L V Y E M +
Sbjct: 1270 LYEGLKVAKE-EWSQTLWINLNVQILQEGIEGFLRALRKLPRPVRGLSVTYYLEAKMKAF 1328
Query: 562 AKAVPEPLKKYTKCRELAERLKIEATYESVLFHQLQEIKGVQQDEALQLPKDLDYL---- 617
++ PL K L +R E ++ +F ++ E ++ A++L K D L
Sbjct: 1329 KDSI--PLLLDLKNEALRDRHWKELMEKTSVFFEMTETFTLENMFAMELHKHTDVLNEIV 1386
Query: 618 --TIRDVSLSHEVREKL 632
I++V++ V+E L
Sbjct: 1387 TAAIKEVAIEKAVKEIL 1403
>gi|19923899 coiled-coil domain containing 45 [Homo sapiens]
Length = 821
Score = 30.0 bits (66), Expect = 7.5
Identities = 29/111 (26%), Positives = 53/111 (47%), Gaps = 14/111 (12%)
Query: 586 ATYESVLFHQLQEIKGV---QQDEALQLPKDLDYLTIR--DVSLSHEVREKLHFSRPQTI 640
A Y+S+L ++ ++ + Q+D+A + +D L + VSLSH E + ++I
Sbjct: 38 ALYQSILGEKVPDLIVIPRSQEDDAHNVQAVIDSLALDYLQVSLSHITGENIVKGDKESI 97
Query: 641 GAASRIPGVTPAAIINLLRFVKTTQRRQSAMNESSKTDQYLCDADRLQERE 691
I LL ++ T+R +E S+T+QY ++DR + E
Sbjct: 98 KNLLEI-------FDGLLEYL--TERISETSHEKSETEQYFKESDRGERLE 139
>gi|51477723 testis expressed sequence 11 isoform 2 [Homo sapiens]
Length = 925
Score = 29.6 bits (65), Expect = 9.8
Identities = 23/102 (22%), Positives = 44/102 (43%), Gaps = 10/102 (9%)
Query: 523 FLSSKWKKLIPEASISTSRSLPVRALDV-LKYEEVDMDSLAKAV-------PEPLKKYTK 574
FL S W+ +P T ++ + A++ Y + + +L KA+ P + +Y+K
Sbjct: 744 FLESVWE--LPHLETKTFETIAIIAMEKPAHYPLIALKALKKALLLYKKEEPIDISQYSK 801
Query: 575 CRELAERLKIEATYESVLFHQLQEIKGVQQDEALQLPKDLDY 616
C L + +V L+E+ G +D + + DY
Sbjct: 802 CMHNLVNLSVPDGASNVELCPLEEVWGYFEDALSHISRTKDY 843
>gi|51477721 testis expressed sequence 11 isoform 1 [Homo sapiens]
Length = 940
Score = 29.6 bits (65), Expect = 9.8
Identities = 23/102 (22%), Positives = 44/102 (43%), Gaps = 10/102 (9%)
Query: 523 FLSSKWKKLIPEASISTSRSLPVRALDV-LKYEEVDMDSLAKAV-------PEPLKKYTK 574
FL S W+ +P T ++ + A++ Y + + +L KA+ P + +Y+K
Sbjct: 759 FLESVWE--LPHLETKTFETIAIIAMEKPAHYPLIALKALKKALLLYKKEEPIDISQYSK 816
Query: 575 CRELAERLKIEATYESVLFHQLQEIKGVQQDEALQLPKDLDY 616
C L + +V L+E+ G +D + + DY
Sbjct: 817 CMHNLVNLSVPDGASNVELCPLEEVWGYFEDALSHISRTKDY 858
>gi|114155142 nuclear pore complex-associated protein TPR [Homo
sapiens]
Length = 2363
Score = 29.6 bits (65), Expect = 9.8
Identities = 26/141 (18%), Positives = 55/141 (39%), Gaps = 5/141 (3%)
Query: 511 LEEGISVLKSIEFLSSKWKKLIPEASISTSRSLPVRALDVLKYEEV-----DMDSLAKAV 565
++E + + ++ + ++K E + + A ++E +M L + +
Sbjct: 1424 IQEKVKTITQVKKIGRRYKTQYEELKAQQDKVMETSAQSSGDHQEQHVSVQEMQELKETL 1483
Query: 566 PEPLKKYTKCRELAERLKIEATYESVLFHQLQEIKGVQQDEALQLPKDLDYLTIRDVSLS 625
+ K E L+ + + LQE Q E +L +DL T ++ L
Sbjct: 1484 NQAETKSKSLESQVENLQKTLSEKETEARNLQEQTVQLQSELSRLRQDLQDRTTQEEQLR 1543
Query: 626 HEVREKLHFSRPQTIGAASRI 646
++ EK +R + A S+I
Sbjct: 1544 QQITEKEEKTRKAIVAAKSKI 1564
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.319 0.136 0.399
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 26,129,412
Number of Sequences: 37866
Number of extensions: 1157328
Number of successful extensions: 2492
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 15
Number of HSP's successfully gapped in prelim test: 15
Number of HSP's that attempted gapping in prelim test: 2472
Number of HSP's gapped (non-prelim): 34
length of query: 692
length of database: 18,247,518
effective HSP length: 109
effective length of query: 583
effective length of database: 14,120,124
effective search space: 8232032292
effective search space used: 8232032292
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.