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Search of human proteins with 73808090
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|73808090 zinc finger protein 207 isoform b [Homo sapiens]
(463 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|73808090 zinc finger protein 207 isoform b [Homo sapiens] 995 0.0
gi|148612835 zinc finger protein 207 isoform c [Homo sapiens] 979 0.0
gi|4508017 zinc finger protein 207 isoform a [Homo sapiens] 933 0.0
gi|7706501 WW domain binding protein 11 [Homo sapiens] 98 2e-20
gi|41349482 proline-rich protein BstNI subfamily 1 isoform 1 pre... 93 4e-19
gi|160707881 formin 2 [Homo sapiens] 89 6e-18
gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens] 89 8e-18
gi|163965366 nascent polypeptide-associated complex alpha subuni... 83 5e-16
gi|21361376 splicing factor 3a, subunit 2 [Homo sapiens] 83 6e-16
gi|224451135 splicing factor, arginine/serine-rich 15 isoform 3 ... 82 1e-15
gi|150170670 piccolo isoform 2 [Homo sapiens] 80 4e-15
gi|150378539 piccolo isoform 1 [Homo sapiens] 80 4e-15
gi|146134388 YLP motif containing 1 [Homo sapiens] 79 1e-14
gi|224451133 splicing factor, arginine/serine-rich 15 isoform 2 ... 78 1e-14
gi|40789229 splicing factor, arginine/serine-rich 15 isoform 1 [... 78 1e-14
gi|47132519 Ras association and pleckstrin homology domains 1 is... 78 2e-14
gi|19718731 bromodomain-containing protein 4 isoform long [Homo ... 76 6e-14
gi|149158690 HLA-B associated transcript-2 [Homo sapiens] 76 7e-14
gi|117306167 proline-rich protein BstNI subfamily 3 precursor [H... 76 7e-14
gi|46852161 methyl-CpG binding domain protein 6 [Homo sapiens] 75 1e-13
gi|55750053 atrophin-1 [Homo sapiens] 74 3e-13
gi|55750041 atrophin-1 [Homo sapiens] 74 3e-13
gi|15890086 type IV collagen alpha 5 isoform 2 precursor [Homo s... 74 4e-13
gi|4502955 type IV collagen alpha 5 isoform 1 precursor [Homo sa... 74 4e-13
gi|15890088 type IV collagen alpha 5 isoform 3 precursor [Homo s... 74 4e-13
gi|42544130 splicing factor 1 isoform 1 [Homo sapiens] 74 4e-13
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 73 6e-13
gi|116284398 WAS/WASL interacting protein family, member 1 [Homo... 73 6e-13
gi|38373695 WAS/WASL interacting protein family, member 1 [Homo ... 73 6e-13
gi|7662046 myeloid/lymphoid or mixed-lineage leukemia 4 [Homo sa... 72 8e-13
>gi|73808090 zinc finger protein 207 isoform b [Homo sapiens]
Length = 463
Score = 995 bits (2572), Expect = 0.0
Identities = 463/463 (100%), Positives = 463/463 (100%)
Query: 1 MGRKKKKQLKPWCWYCNRDFDDEKILIQHQKAKHFKCHICHKKLYTGPGLAIHCMQVHKE 60
MGRKKKKQLKPWCWYCNRDFDDEKILIQHQKAKHFKCHICHKKLYTGPGLAIHCMQVHKE
Sbjct: 1 MGRKKKKQLKPWCWYCNRDFDDEKILIQHQKAKHFKCHICHKKLYTGPGLAIHCMQVHKE 60
Query: 61 TIDAVPNAIPGRTDIELEIYGMEGIPEKDMDERRRLLEQKTQESQKKKQQDDSDEYDDDD 120
TIDAVPNAIPGRTDIELEIYGMEGIPEKDMDERRRLLEQKTQESQKKKQQDDSDEYDDDD
Sbjct: 61 TIDAVPNAIPGRTDIELEIYGMEGIPEKDMDERRRLLEQKTQESQKKKQQDDSDEYDDDD 120
Query: 121 SAASTSFQPQPVQPQQGYIPPMAQPGLPPVPGAPGMPPGIPPLMPGVPPLMPGMPPVMPG 180
SAASTSFQPQPVQPQQGYIPPMAQPGLPPVPGAPGMPPGIPPLMPGVPPLMPGMPPVMPG
Sbjct: 121 SAASTSFQPQPVQPQQGYIPPMAQPGLPPVPGAPGMPPGIPPLMPGVPPLMPGMPPVMPG 180
Query: 181 MPPGLHHQRKYTQSFCGENIMMPMGGMMPPGPGIPPLMPGMPPGMPPPVPRPGIPPMTQA 240
MPPGLHHQRKYTQSFCGENIMMPMGGMMPPGPGIPPLMPGMPPGMPPPVPRPGIPPMTQA
Sbjct: 181 MPPGLHHQRKYTQSFCGENIMMPMGGMMPPGPGIPPLMPGMPPGMPPPVPRPGIPPMTQA 240
Query: 241 QAVSAPGILNRPPAPTATVPAPQPPVTKPLFPSAGQAQAAVQGPVGTDFKPLNSTPATTT 300
QAVSAPGILNRPPAPTATVPAPQPPVTKPLFPSAGQAQAAVQGPVGTDFKPLNSTPATTT
Sbjct: 241 QAVSAPGILNRPPAPTATVPAPQPPVTKPLFPSAGQAQAAVQGPVGTDFKPLNSTPATTT 300
Query: 301 EPPKPTFPAYTQSTASTTSTTNSTAAKPAASITSKPATLTTTSATSKLIHPDEDISLEER 360
EPPKPTFPAYTQSTASTTSTTNSTAAKPAASITSKPATLTTTSATSKLIHPDEDISLEER
Sbjct: 301 EPPKPTFPAYTQSTASTTSTTNSTAAKPAASITSKPATLTTTSATSKLIHPDEDISLEER 360
Query: 361 RAQLPKYQRNLPRPGQAPIGNPPVGPIGGMMPPQPGIPQQQGMRPPMPPHGQYGGHHQGM 420
RAQLPKYQRNLPRPGQAPIGNPPVGPIGGMMPPQPGIPQQQGMRPPMPPHGQYGGHHQGM
Sbjct: 361 RAQLPKYQRNLPRPGQAPIGNPPVGPIGGMMPPQPGIPQQQGMRPPMPPHGQYGGHHQGM 420
Query: 421 PGYLPGAMPPYGQGPPMVPPYQGGPPRPPMGMRPPVMSQGGRY 463
PGYLPGAMPPYGQGPPMVPPYQGGPPRPPMGMRPPVMSQGGRY
Sbjct: 421 PGYLPGAMPPYGQGPPMVPPYQGGPPRPPMGMRPPVMSQGGRY 463
>gi|148612835 zinc finger protein 207 isoform c [Homo sapiens]
Length = 494
Score = 979 bits (2530), Expect = 0.0
Identities = 463/494 (93%), Positives = 463/494 (93%), Gaps = 31/494 (6%)
Query: 1 MGRKKKKQLKPWCWYCNRDFDDEKILIQHQKAKHFKCHICHKKLYTGPGLAIHCMQVHKE 60
MGRKKKKQLKPWCWYCNRDFDDEKILIQHQKAKHFKCHICHKKLYTGPGLAIHCMQVHKE
Sbjct: 1 MGRKKKKQLKPWCWYCNRDFDDEKILIQHQKAKHFKCHICHKKLYTGPGLAIHCMQVHKE 60
Query: 61 TIDAVPNAIPGRTDIELEIYGMEGIPEKDMDERRRLLEQKTQESQKKKQQDDSDEYDDDD 120
TIDAVPNAIPGRTDIELEIYGMEGIPEKDMDERRRLLEQKTQESQKKKQQDDSDEYDDDD
Sbjct: 61 TIDAVPNAIPGRTDIELEIYGMEGIPEKDMDERRRLLEQKTQESQKKKQQDDSDEYDDDD 120
Query: 121 SAASTSFQPQPVQPQQGYIPPMAQPGLPPVPGAPGMPPGIPPLMPGVPPLMPGMPPVMPG 180
SAASTSFQPQPVQPQQGYIPPMAQPGLPPVPGAPGMPPGIPPLMPGVPPLMPGMPPVMPG
Sbjct: 121 SAASTSFQPQPVQPQQGYIPPMAQPGLPPVPGAPGMPPGIPPLMPGVPPLMPGMPPVMPG 180
Query: 181 MPPGLHHQRKYTQSFCGENIMMPMGGMMPPGPGIPPLMPGMPPGMPPPVPRPGIPPMTQA 240
MPPGLHHQRKYTQSFCGENIMMPMGGMMPPGPGIPPLMPGMPPGMPPPVPRPGIPPMTQA
Sbjct: 181 MPPGLHHQRKYTQSFCGENIMMPMGGMMPPGPGIPPLMPGMPPGMPPPVPRPGIPPMTQA 240
Query: 241 QAVSAPGILNRPPAPTATVPAPQPPVTKPLFPSAG------------------------- 275
QAVSAPGILNRPPAPTATVPAPQPPVTKPLFPSAG
Sbjct: 241 QAVSAPGILNRPPAPTATVPAPQPPVTKPLFPSAGQMGTPVTSSSTASSNSESLSASSKA 300
Query: 276 ------QAQAAVQGPVGTDFKPLNSTPATTTEPPKPTFPAYTQSTASTTSTTNSTAAKPA 329
QAQAAVQGPVGTDFKPLNSTPATTTEPPKPTFPAYTQSTASTTSTTNSTAAKPA
Sbjct: 301 LFPSTAQAQAAVQGPVGTDFKPLNSTPATTTEPPKPTFPAYTQSTASTTSTTNSTAAKPA 360
Query: 330 ASITSKPATLTTTSATSKLIHPDEDISLEERRAQLPKYQRNLPRPGQAPIGNPPVGPIGG 389
ASITSKPATLTTTSATSKLIHPDEDISLEERRAQLPKYQRNLPRPGQAPIGNPPVGPIGG
Sbjct: 361 ASITSKPATLTTTSATSKLIHPDEDISLEERRAQLPKYQRNLPRPGQAPIGNPPVGPIGG 420
Query: 390 MMPPQPGIPQQQGMRPPMPPHGQYGGHHQGMPGYLPGAMPPYGQGPPMVPPYQGGPPRPP 449
MMPPQPGIPQQQGMRPPMPPHGQYGGHHQGMPGYLPGAMPPYGQGPPMVPPYQGGPPRPP
Sbjct: 421 MMPPQPGIPQQQGMRPPMPPHGQYGGHHQGMPGYLPGAMPPYGQGPPMVPPYQGGPPRPP 480
Query: 450 MGMRPPVMSQGGRY 463
MGMRPPVMSQGGRY
Sbjct: 481 MGMRPPVMSQGGRY 494
>gi|4508017 zinc finger protein 207 isoform a [Homo sapiens]
Length = 478
Score = 933 bits (2411), Expect = 0.0
Identities = 447/494 (90%), Positives = 447/494 (90%), Gaps = 47/494 (9%)
Query: 1 MGRKKKKQLKPWCWYCNRDFDDEKILIQHQKAKHFKCHICHKKLYTGPGLAIHCMQVHKE 60
MGRKKKKQLKPWCWYCNRDFDDEKILIQHQKAKHFKCHICHKKLYTGPGLAIHCMQVHKE
Sbjct: 1 MGRKKKKQLKPWCWYCNRDFDDEKILIQHQKAKHFKCHICHKKLYTGPGLAIHCMQVHKE 60
Query: 61 TIDAVPNAIPGRTDIELEIYGMEGIPEKDMDERRRLLEQKTQESQKKKQQDDSDEYDDDD 120
TIDAVPNAIPGRTDIELEIYGMEGIPEKDMDERRRLLEQKTQESQKKKQQDDSDEYDDDD
Sbjct: 61 TIDAVPNAIPGRTDIELEIYGMEGIPEKDMDERRRLLEQKTQESQKKKQQDDSDEYDDDD 120
Query: 121 SAASTSFQPQPVQPQQGYIPPMAQPGLPPVPGAPGMPPGIPPLMPGVPPLMPGMPPVMPG 180
SAASTSFQPQPVQPQQGYIPPMAQPGLPPVPGAPGMPPGIPPLMPGVPPLMPGMPPVMPG
Sbjct: 121 SAASTSFQPQPVQPQQGYIPPMAQPGLPPVPGAPGMPPGIPPLMPGVPPLMPGMPPVMPG 180
Query: 181 MPPGLHHQRKYTQSFCGENIMMPMGGMMPPGPGIPPLMPGMPPGMPPPVPRPGIPPMTQA 240
MPPG MMPMGGMMPPGPGIPPLMPGMPPGMPPPVPRPGIPPMTQA
Sbjct: 181 MPPG----------------MMPMGGMMPPGPGIPPLMPGMPPGMPPPVPRPGIPPMTQA 224
Query: 241 QAVSAPGILNRPPAPTATVPAPQPPVTKPLFPSAGQ------------------------ 276
QAVSAPGILNRPPAPTATVPAPQPPVTKPLFPSAGQ
Sbjct: 225 QAVSAPGILNRPPAPTATVPAPQPPVTKPLFPSAGQMGTPVTSSSTASSNSESLSASSKA 284
Query: 277 -------AQAAVQGPVGTDFKPLNSTPATTTEPPKPTFPAYTQSTASTTSTTNSTAAKPA 329
AQAAVQGPVGTDFKPLNSTPATTTEPPKPTFPAYTQSTASTTSTTNSTAAKPA
Sbjct: 285 LFPSTAQAQAAVQGPVGTDFKPLNSTPATTTEPPKPTFPAYTQSTASTTSTTNSTAAKPA 344
Query: 330 ASITSKPATLTTTSATSKLIHPDEDISLEERRAQLPKYQRNLPRPGQAPIGNPPVGPIGG 389
ASITSKPATLTTTSATSKLIHPDEDISLEERRAQLPKYQRNLPRPGQAPIGNPPVGPIGG
Sbjct: 345 ASITSKPATLTTTSATSKLIHPDEDISLEERRAQLPKYQRNLPRPGQAPIGNPPVGPIGG 404
Query: 390 MMPPQPGIPQQQGMRPPMPPHGQYGGHHQGMPGYLPGAMPPYGQGPPMVPPYQGGPPRPP 449
MMPPQPGIPQQQGMRPPMPPHGQYGGHHQGMPGYLPGAMPPYGQGPPMVPPYQGGPPRPP
Sbjct: 405 MMPPQPGIPQQQGMRPPMPPHGQYGGHHQGMPGYLPGAMPPYGQGPPMVPPYQGGPPRPP 464
Query: 450 MGMRPPVMSQGGRY 463
MGMRPPVMSQGGRY
Sbjct: 465 MGMRPPVMSQGGRY 478
>gi|7706501 WW domain binding protein 11 [Homo sapiens]
Length = 641
Score = 97.8 bits (242), Expect = 2e-20
Identities = 79/240 (32%), Positives = 105/240 (43%), Gaps = 37/240 (15%)
Query: 103 ESQKKKQQDDSDEYDDDDSAASTSFQ---PQPVQPQQGYIPPM-AQPGLPPVPGAPGMPP 158
E++K+ Q+ +E D ++ ++S Q PQ V P Q PPM P L P P P PP
Sbjct: 365 EAEKQSQKQHKEESHSDGTSTASSQQQAPPQSVPPSQIQAPPMPGPPPLGPPPAPPLRPP 424
Query: 159 GIPPLMPGVPPLMPGMPPVM--PGMPPGLHHQRKYTQSFCGENIMMPMGGMMPPGPGIPP 216
G P +P PP PG PP + PGMP + P+ ++PPGP
Sbjct: 425 GPPTGLPPGPP--PGAPPFLRPPGMP----------------GLRGPLPRLLPPGP---- 462
Query: 217 LMPGMPPGMPPPVPRPGIPPMTQAQAVSAPGILNRPPAPTATVPAPQPPVTK-PLFPSAG 275
PG PPG PPP P PG+PP P PPAP +P P+P + + PL P G
Sbjct: 463 -PPGRPPG-PPPGPPPGLPP---GPPPRGPPPRLPPPAPPG-IPPPRPGMMRPPLVPPLG 516
Query: 276 QAQAAVQGPVGTDFKPLNSTPATTTEPPK--PTFPAYTQSTASTTSTTNSTAAKPAASIT 333
A + P + S P + PK T A + A+ T + P A IT
Sbjct: 517 PAPPGLFPPAPLPNPGVLSAPPNLIQRPKADDTSAATIEKKATATISAKPQITNPKAEIT 576
Score = 59.3 bits (142), Expect = 7e-09
Identities = 45/139 (32%), Positives = 62/139 (44%), Gaps = 31/139 (22%)
Query: 341 TTSATSKLIHPDEDISLEERRAQLPKYQRNLPRPGQAPIGNPPVGPIGGMMPP------- 393
T++A+S+ P + + + +A P PG P+G PP P+ PP
Sbjct: 383 TSTASSQQQAPPQSVPPSQIQAP--------PMPGPPPLGPPPAPPLRPPGPPTGLPPGP 434
Query: 394 ---------QPGIPQQQG----MRPPMPPHGQYGGHHQGMPGYLPGAMPPYGQGPPMVPP 440
PG+P +G + PP PP G+ G G P LP PP G P + PP
Sbjct: 435 PPGAPPFLRPPGMPGLRGPLPRLLPPGPPPGRPPGPPPGPPPGLPPGPPPRGPPPRLPPP 494
Query: 441 YQGG--PPRPPMGMRPPVM 457
G PPRP M MRPP++
Sbjct: 495 APPGIPPPRPGM-MRPPLV 512
Score = 34.3 bits (77), Expect = 0.25
Identities = 30/108 (27%), Positives = 44/108 (40%), Gaps = 7/108 (6%)
Query: 354 DISLEERRAQLPKYQRNLPRPGQAPIGNPPVGPIGGMMPPQPGIPQQQGMRPP--MPPHG 411
++ E++RAQL +Y + + + P+ MP P Q + P PP
Sbjct: 111 EVEYEQKRAQLSQYFDAVKNAQHVEVESIPLPD----MPHAPSNILIQDIPLPGAQPPSI 166
Query: 412 QYGGHHQGMPGYLPGAMPPYGQGPPMVPPYQGGPPRPPMGMRPPVMSQ 459
G P +P G G P +PP + PP PP G PP + Q
Sbjct: 167 LKKTSAYGPPTRAVSILPLLGHGVPRLPPGR-KPPGPPPGPPPPQVVQ 213
Score = 30.8 bits (68), Expect = 2.7
Identities = 20/53 (37%), Positives = 24/53 (45%), Gaps = 18/53 (33%)
Query: 202 MPMGGMMPP---------GP-----GIPPLM----PGMPPGMPPPVPRPGIPP 236
+P+ G PP GP I PL+ P +PPG PP P PG PP
Sbjct: 156 IPLPGAQPPSILKKTSAYGPPTRAVSILPLLGHGVPRLPPGRKPPGPPPGPPP 208
Score = 29.6 bits (65), Expect = 6.0
Identities = 28/90 (31%), Positives = 37/90 (41%), Gaps = 16/90 (17%)
Query: 149 PVPGAPGMPPGIPPLMPGVPPLMPGMPPVMPGMPPGLHHQRKYTQSFCGENIMMPMGGMM 208
P+P P P I L+ +P +PG P P L Y +I+ +G
Sbjct: 140 PLPDMPHAPSNI--LIQDIP--LPGAQP-----PSILKKTSAYGPPTRAVSILPLLGH-- 188
Query: 209 PPGPGIPPLMPGM-PPGMPPPVPRPGIPPM 237
G+P L PG PPG PP P P + M
Sbjct: 189 ----GVPRLPPGRKPPGPPPGPPPPQVVQM 214
>gi|41349482 proline-rich protein BstNI subfamily 1 isoform 1
preproprotein [Homo sapiens]
Length = 331
Score = 93.2 bits (230), Expect = 4e-19
Identities = 105/349 (30%), Positives = 125/349 (35%), Gaps = 43/349 (12%)
Query: 110 QDDSDEYDDDDSAASTSFQPQPVQPQQGYIPPMAQPGLPPVPGAPGMPPGIPPLMPGVPP 169
Q+ +++ ++S + + PQ PQ G P G PP PG P PP P PP
Sbjct: 17 QNLNEDVSQEESPSLIAGNPQGPSPQGGNKPQ----GPPPPPGKPQGPPPQGGNKPQGPP 72
Query: 170 LMPGMPPVMPGMPPGLHHQRKYTQSFCGE-NIMMPMGGMMPPGPGIPPLMPGMPPGMPPP 228
PP P PP + + +S G+ P GG P GP PP P PP P
Sbjct: 73 -----PPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPP--PQG 125
Query: 229 VPRPGIPPMTQAQAVSAPGILNRPPAPTATVPAPQPPVTKPLFPSAGQAQAAVQGPVGTD 288
RP PP PG PP +P+ P KP P Q QGP
Sbjct: 126 GNRPQGPP--------PPGKPQGPPPQGDKSRSPRSPPGKPQGPPP-QGGNQPQGPPPPP 176
Query: 289 FKPLNSTPATTTEPPKPTFPAYTQSTASTTSTTNSTAAKPAASITSKPATLTTTSATSKL 348
KP P +P P P Q + S+ + P KP
Sbjct: 177 GKPQGPPPQGGKKPQGPPPPGKPQGPPPQGDKSRSSQSPPG-----KPQGPPPQGGNQPQ 231
Query: 349 IHPDEDISLEERRAQLPKYQRNLPRPGQAPIGNPPVGPIGGMMPPQPGIPQQQGMRPPMP 408
P K Q P+ G P G PP G G P Q G Q PP
Sbjct: 232 GPPPPP----------GKPQGPPPQGGNKPQGPPPPGKPQGP-PAQGGSKSQSARSPPGK 280
Query: 409 PHG---QYGGHHQGMPGYLPGAMPPYGQGPPMVPPYQGGPPRPPMGMRP 454
P G Q G + QG P G P Q PP P GPPRPP G RP
Sbjct: 281 PQGPPQQEGNNPQGPPPPA-GGNPQQPQAPPAGQPQ--GPPRPPQGGRP 326
Score = 64.7 bits (156), Expect = 2e-10
Identities = 73/265 (27%), Positives = 79/265 (29%), Gaps = 50/265 (18%)
Query: 203 PMGGMMPPGPGIPPLMPGMPPGMPPPVPRPGIPPMTQAQAVSAPGILNRPPAPTATVPAP 262
P GG P GP PP P PP P+ G P Q PG PP +P
Sbjct: 41 PQGGNKPQGPPPPPGKPQGPP------PQGGNKP----QGPPPPGKPQGPPPQGDKSRSP 90
Query: 263 QPPVTKPLFPSAGQAQAAVQGPVGTDFKPLNSTPATTTEPPKPTFPAYTQSTASTTSTTN 322
+ P KP P Q QGP KP P P P P Q +
Sbjct: 91 RSPPGKPQGPPP-QGGNQPQGPPPPPGKPQGPPPQGGNRPQGPPPPGKPQGPPPQGDKSR 149
Query: 323 STAAKPAASITSKPATLTTTSATSKLIHPDEDISLEERRAQLPKYQRNLPRPGQAPIGNP 382
S + P P Q + P P P G P
Sbjct: 150 SPRSPPGKPQGPPP--------------------------QGGNQPQGPPPPPGKPQGPP 183
Query: 383 PVGPIGGMMPPQPGIPQQQGMRPPMPPHGQYGGHHQGMPGYLPGAMPPYGQGPPMVPPYQ 442
P G PP PG PQ PP G Q PG G P G P PP
Sbjct: 184 PQGGKKPQGPPPPGKPQGP------PPQGDKSRSSQSPPGKPQGPPPQGGNQPQGPPPPP 237
Query: 443 GGPPRP-------PMGMRPPVMSQG 460
G P P P G PP QG
Sbjct: 238 GKPQGPPPQGGNKPQGPPPPGKPQG 262
Score = 46.6 bits (109), Expect = 5e-05
Identities = 43/124 (34%), Positives = 49/124 (39%), Gaps = 15/124 (12%)
Query: 344 ATSKLIHPDEDISLEERRAQLPKYQRNLPRPGQAPIGNPPVGPIGGMMPPQPGIPQ---- 399
A S + +ED+S EE P P+ GN P GP PP PG PQ
Sbjct: 12 ALSSAQNLNEDVSQEES----PSLIAGNPQGPSPQGGNKPQGP-----PPPPGKPQGPPP 62
Query: 400 QQGMRP--PMPPHGQYGGHHQGMPGYLPGAMPPYGQGPPMVPPYQGGPPRPPMGMRPPVM 457
Q G +P P PP G QG P + P QGPP Q P PP G
Sbjct: 63 QGGNKPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPP 122
Query: 458 SQGG 461
QGG
Sbjct: 123 PQGG 126
Score = 46.2 bits (108), Expect = 6e-05
Identities = 43/136 (31%), Positives = 49/136 (36%), Gaps = 10/136 (7%)
Query: 108 KQQDDSDEYDDDDSAASTSFQPQPVQPQ-----QGYIPPMAQPGLPPVPGA--PGMPPGI 160
K Q + D S+ S +PQ PQ QG PP +P PP G P PP
Sbjct: 198 KPQGPPPQGDKSRSSQSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPP-- 255
Query: 161 PPLMPGVPPLMPGMPPVMPGMPPGLHHQRKYTQSFCGENIMMPMGGMMPPGPGIPPLMPG 220
PP P PP G PPG + + P GG P P PP
Sbjct: 256 PPGKPQGPPAQGGSKSQSARSPPGKPQGPPQQEGNNPQGPPPPAGGN-PQQPQAPPAGQP 314
Query: 221 MPPGMPPPVPRPGIPP 236
P PP RP PP
Sbjct: 315 QGPPRPPQGGRPSRPP 330
Score = 45.4 bits (106), Expect = 1e-04
Identities = 37/108 (34%), Positives = 44/108 (40%), Gaps = 11/108 (10%)
Query: 361 RAQLPKYQRNLPRPGQAPIGNPPVGPIGGMMPPQPGIPQ----QQGMRP--PMPPHGQYG 414
+++ P+ P+ GN P GP PP PG PQ Q G RP P PP G
Sbjct: 86 KSRSPRSPPGKPQGPPPQGGNQPQGP-----PPPPGKPQGPPPQGGNRPQGPPPPGKPQG 140
Query: 415 GHHQGMPGYLPGAMPPYGQGPPMVPPYQGGPPRPPMGMRPPVMSQGGR 462
QG P + P QGPP Q P PP G QGG+
Sbjct: 141 PPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGK 188
>gi|160707881 formin 2 [Homo sapiens]
Length = 1722
Score = 89.4 bits (220), Expect = 6e-18
Identities = 109/377 (28%), Positives = 133/377 (35%), Gaps = 81/377 (21%)
Query: 129 PQPVQPQQGYIPPMAQPG-----LPPVPGAPGMPPGIPPLMPG--VPPLMPGMPPVMPG- 180
P P P G PP PG LPP+PGA G+PP PP +PG +PP PP +PG
Sbjct: 911 PPPPLPGAGIPPPPPLPGAGILPLPPLPGA-GIPP--PPPLPGAAIPP-----PPPLPGA 962
Query: 181 ---MPPGLHHQRKYTQSFCGENIMMPMGGMMPPGPGIPPLMPGMPPGMPPPVPRP--GIP 235
+PP L PG GIPP P G+PPP P P GIP
Sbjct: 963 GIPLPPPL------------------------PGAGIPPPPPLPGAGIPPPPPLPGAGIP 998
Query: 236 PMTQAQAVSAP--------GILNRPPAPTATVPAPQPPVTKPLFPSAGQAQAAVQGP--- 284
P P GI PP P A +P P P + P A + P
Sbjct: 999 PPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPL 1058
Query: 285 VGTDFKPLNSTPATTTEPPKPTFPAYTQSTASTTSTTNSTAAKPAASITSKPATLTTTSA 344
G P P PP P P P + P +
Sbjct: 1059 PGAGIPPPPPLPGAGI-PPPPPLPGAGIPPPPPLPGAGIPPPPPLPGVGIPPPPPLPGAG 1117
Query: 345 TSKLIHPDEDISLEERRAQLPKYQRNLPRPGQAP-IGNPPVGPI--GGMMPPQP----GI 397
I P + P +P P P +G PP P+ G+ PP P GI
Sbjct: 1118 ----IPPPPPLPGAGIPPPPPLPGAGIPPPPPLPRVGIPPPPPLPGAGIPPPPPLPGAGI 1173
Query: 398 PQQQ-----GMRPP-------MPPHGQYGGHHQGMPGYLPGAMPPYGQGPPMVPPYQGGP 445
P G+ PP +PP G P LPG P PP+ PP G P
Sbjct: 1174 PPPPPLPGVGIPPPPPLPGVGIPPPPPLPGAGIPPPPPLPGMGIPPAPAPPLPPPGTGIP 1233
Query: 446 PRPPMGMR-PPVMSQGG 461
P P + + PP++ Q G
Sbjct: 1234 PPPLLPVSGPPLLPQVG 1250
Score = 76.3 bits (186), Expect = 6e-14
Identities = 95/344 (27%), Positives = 119/344 (34%), Gaps = 67/344 (19%)
Query: 143 AQPGL----PPVPGAPGMP-PGIPPLMPGVPPLMPGMPPVMPGMPPGLHHQRKYTQSFCG 197
+ PGL PP P PGM P +P PP + G + P PP G
Sbjct: 869 SMPGLGMVPPPPPPLPGMTVPTLPSTAIPQPPPLQGTEMLPPPPPPLPGAGIPPPPPLPG 928
Query: 198 ENIM----MPMGGMMPPGP------GIPPLMPGMPPGMPPPVPRPGIPPMTQAQAVSAP- 246
I+ +P G+ PP P PP +PG +PPP+P GIPP P
Sbjct: 929 AGILPLPPLPGAGIPPPPPLPGAAIPPPPPLPGAGIPLPPPLPGAGIPPPPPLPGAGIPP 988
Query: 247 -------GILNRPPAPTATVPAPQPPVTKPLFPSAGQAQAAVQGP---VGTDFKPLNSTP 296
GI PP P A +P P P + P A + P G P P
Sbjct: 989 PPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLP 1048
Query: 297 ATTTEPPKPTFPAYTQSTASTTSTTNSTAAKPAASITSKPATLTTTSATSKLIHPDEDIS 356
PP P P A I P I P +
Sbjct: 1049 GAGIPPPPPL---------------------PGAGIPPPP------PLPGAGIPPPPPLP 1081
Query: 357 LEERRAQLPKYQRNLPRPGQAP-IGNPPVGPI-GGMMPPQPGIPQQQGMRPPMPPHGQYG 414
P +P P P +G PP P+ G +PP P +P G+ PP P G
Sbjct: 1082 GAGIPPPPPLPGAGIPPPPPLPGVGIPPPPPLPGAGIPPPPPLP-GAGIPPPPPLPG--- 1137
Query: 415 GHHQGMPGYLPGAMPPYGQGPPMVPPYQGGPPRPPM---GMRPP 455
G+P P +P G PP P G PP PP+ G+ PP
Sbjct: 1138 ---AGIPP--PPPLPRVGIPPPPPLPGAGIPPPPPLPGAGIPPP 1176
Score = 72.4 bits (176), Expect = 8e-13
Identities = 64/180 (35%), Positives = 78/180 (43%), Gaps = 45/180 (25%)
Query: 129 PQPVQPQQGYIPPMAQPGL-----PPVPGAPGMPPGIPPLMPGV----PPLMPGM----P 175
P P P G PP PG+ PP+PGA G+PP PP +PG PP +PG P
Sbjct: 1087 PPPPLPGAGIPPPPPLPGVGIPPPPPLPGA-GIPP--PPPLPGAGIPPPPPLPGAGIPPP 1143
Query: 176 PVMP--GMPPGLHHQRKYTQSFCGENIM----MPMGGMMPPGP----GIPPLMP----GM 221
P +P G+PP G I +P G+ PP P GIPP P G+
Sbjct: 1144 PPLPRVGIPP--------PPPLPGAGIPPPPPLPGAGIPPPPPLPGVGIPPPPPLPGVGI 1195
Query: 222 PPGMPPPVPRPGIPPMTQAQAVSAPGILNRPPAPTATVPAPQPPVT----KPLFPSAGQA 277
PP PPP+P GIPP + P PP P P PP+ PL P G +
Sbjct: 1196 PP--PPPLPGAGIPPPPPLPGMGIPP-APAPPLPPPGTGIPPPPLLPVSGPPLLPQVGSS 1252
Score = 68.6 bits (166), Expect = 1e-11
Identities = 97/337 (28%), Positives = 120/337 (35%), Gaps = 75/337 (22%)
Query: 145 PGLPPVPGAP--------GMPPGIPPLMPGVPPLMPGMPPVMPGMPPGLHHQRKYTQSFC 196
P PP+P GM P PP +PG+ +P +P PP L
Sbjct: 856 PSPPPLPCTESSSSMPGLGMVPPPPPPLPGMT--VPTLPSTAIPQPPPLQGTE------- 906
Query: 197 GENIMMPMGGMMPPGPGIPPLM-PGMPPGMPPPVPRPGIPPMTQAQAVSAPGILNRPPAP 255
M+PP P PPL G+PP PPP+P GI P+ + GI PP P
Sbjct: 907 ----------MLPPPP--PPLPGAGIPP--PPPLPGAGILPL---PPLPGAGIPPPPPLP 949
Query: 256 TATVPAPQP------PVTKPLFPSAGQAQAAVQGP---VGTDFKPLNSTPATTTEPPKPT 306
A +P P P P+ PL P AG + P G P P PP P
Sbjct: 950 GAAIPPPPPLPGAGIPLPPPL-PGAG-----IPPPPPLPGAGIPPPPPLPGAGIPPPPPL 1003
Query: 307 FPAYTQSTASTTSTTNSTAAKPAASITSKPATLTTTSATSKLIHPDEDISLEERRAQLPK 366
A P A I P I P + P
Sbjct: 1004 PGAGIPPPPPL----------PGAGIPPPP------PLPGAGIPPPPPLPGAGIPPPPPL 1047
Query: 367 YQRNLPRPGQAP-IGNPPVGPI-GGMMPPQPGIPQQQGMRPPMPPHGQYGGHHQGMPGY- 423
+P P P G PP P+ G +PP P +P G+ PP P G +PG
Sbjct: 1048 PGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLP-GAGIPPPPPLPGAGIPPPPPLPGVG 1106
Query: 424 LPGAMPPYGQGPPMVPPYQGG--PPRPPM---GMRPP 455
+P P G G P PP G PP PP+ G+ PP
Sbjct: 1107 IPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPP 1143
Score = 60.1 bits (144), Expect = 4e-09
Identities = 58/167 (34%), Positives = 74/167 (44%), Gaps = 60/167 (35%)
Query: 129 PQPVQPQQGYIPPMAQPGL-----PPVPGAPGMPPGIPPLMPGV----PPLMPGM----P 175
P P P+ G PP PG PP+PGA G+PP PP +PGV PP +PG+ P
Sbjct: 1142 PPPPLPRVGIPPPPPLPGAGIPPPPPLPGA-GIPP--PPPLPGVGIPPPPPLPGVGIPPP 1198
Query: 176 PVMPGM----PPGLHHQRKYTQSFCGENIMMPMGGMMP-PGPGIPPLMPGMPPGMPPPVP 230
P +PG PP L P G+ P P P +PP G+PP PP +P
Sbjct: 1199 PPLPGAGIPPPPPL-----------------PGMGIPPAPAPPLPPPGTGIPP--PPLLP 1239
Query: 231 RPGIPPMTQAQAVSAPGILNRPPAPTATVPAPQ------PPVTKPLF 271
VS P +L P ++T+P PQ PP+ LF
Sbjct: 1240 ------------VSGPPLL--PQVGSSTLPTPQVCGFLPPPLPSGLF 1272
Score = 53.9 bits (128), Expect = 3e-07
Identities = 75/288 (26%), Positives = 105/288 (36%), Gaps = 68/288 (23%)
Query: 214 IPPL--MPGMPPGMPPPVPRPGIPPMTQAQAVSAPGILN---RPPAPTATVPAPQPPVTK 268
+PP+ +PG PP P P ++ + +P ++ PT ++ P PP +
Sbjct: 757 LPPVDGLPGRPPCPPGAESGPQTKFCSEISLIVSPRRISVQLDSHQPTQSISQPPPPPS- 815
Query: 269 PLFPSAGQAQAAVQGP--VGTDFK---------------------PLNSTPATTT----- 300
L SAGQ Q Q P + T+F+ PL T ++++
Sbjct: 816 -LLWSAGQGQPGSQPPHSISTEFQTSHEHSVSSAFKNSCNIPSPPPLPCTESSSSMPGLG 874
Query: 301 --EPPKPTFPAYTQSTASTTSTTNSTAAKPAASITSKPATLTTTSATSKLIHPDEDISLE 358
PP P P T T +T+ + + P L P I
Sbjct: 875 MVPPPPPPLPGMTVPTLPSTAIPQPPPLQGTEMLPPPPPPLPGAGIPPPPPLPGAGI--- 931
Query: 359 ERRAQLPKYQRNLPRPGQAPIGNPPVGPI-GGMMPPQPGIPQQQGMRPPMPPHGQYGGHH 417
LP P G PP P+ G +PP P +P G P+PP G
Sbjct: 932 ------------LPLPPLPGAGIPPPPPLPGAAIPPPPPLP---GAGIPLPPPLPGAGIP 976
Query: 418 QGMPGYLPGA-MPPY----GQGPPMVPPYQGG--PPRPPM---GMRPP 455
P LPGA +PP G G P PP G PP PP+ G+ PP
Sbjct: 977 PPPP--LPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPP 1022
Score = 31.2 bits (69), Expect = 2.1
Identities = 59/280 (21%), Positives = 91/280 (32%), Gaps = 52/280 (18%)
Query: 76 ELEIYGMEGIPEK-----DMDERRRLLEQKTQESQKKKQQDDSDEY---DDDDSAASTSF 127
+ +IY E+ D+ + RL +Q+ Q+ Q + QQ + ++ +A T+
Sbjct: 180 DTDIYSFHSATEQEDLLSDIQQAIRLQQQQQQQLQLQLQQQQQQQQLQGAEEPAAPPTAV 239
Query: 128 QPQPVQPQQGYIPPMAQPGLPPVPGAPGMPPGIPPLMPGVPPLMP-----GMPPVMPGMP 182
PQP G + + L P GA G PG P + L P P P
Sbjct: 240 SPQP-----GAFLGLDRFLLGPSGGA-GEAPGSPDTEQALSALSDLPESLAAEPREPQQP 293
Query: 183 PGLHHQRKYTQSFCGENIMMPMGGMMPPGPGIPPLMPG---MPPGMPPPVPRPGIPPMTQ 239
P P G + P +P P P P P G
Sbjct: 294 PS------------------PGGLPVSEAPSLPAAQPAAKDSPSSTAFPFPEAGPGEEAA 335
Query: 240 AQAVSAPGILNRPPAPTATVPAPQPPVTKPLFPSAG---------QAQAAVQGPVGTDFK 290
V G + A AP+ + P G + + QGP
Sbjct: 336 GAPVRGAGDTDEEGEEDAFEDAPRGSPGEEWAPEVGEDAPQRLGEEPEEEAQGPDAPAAA 395
Query: 291 PLNSTPATTTEPPKP---TFPAYTQSTASTTSTTNSTAAK 327
L +PA + KP P Y ++T S+ N + ++
Sbjct: 396 SLPGSPAPSQRCFKPYPLITPCYIKTTTRQLSSPNHSPSQ 435
>gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens]
Length = 416
Score = 89.0 bits (219), Expect = 8e-18
Identities = 106/361 (29%), Positives = 126/361 (34%), Gaps = 61/361 (16%)
Query: 108 KQQDDSDEYDDDDSAASTSFQPQPVQPQQGYIPPMAQPGLPPVPGAPGMPPGIPPLMPGV 167
K Q + D S S +PQ PQ G P G PP PG P PP P
Sbjct: 97 KPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQ----GPPPPPGKPQGPPPQGGNKPQG 152
Query: 168 PPLMPGMPPVMPGMPPGLHHQRKYTQSFCGE-NIMMPMGGMMPPGPGIPPLMPGMPP--- 223
PP PG P G PP ++ + ++S G+ P GG P GP PP P PP
Sbjct: 153 PP-PPGKPQ---GPPPQGDNKSRSSRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQG 208
Query: 224 -----GMPPPVPRPGIPPMTQAQAVSAPGILNRPPAPTATVPAPQPPVTKPLFPSAGQAQ 278
G PPP G PP ++ SA +P P PP Q
Sbjct: 209 GNKPQGPPPPGKPQGPPPQGDNKSQSARSPPGKPQGP--------PP----------QGG 250
Query: 279 AAVQGPVGTDFKPLNSTPATTTEPPKPTFPAYTQSTASTTSTTNSTAAKPAASITSKPAT 338
QGP KP P +P P P Q + + ++ P P
Sbjct: 251 NQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGGSKSRSSRSPPGKPQGPP-- 308
Query: 339 LTTTSATSKLIHPDEDISLEERRAQLPKYQRNLPRPGQAPIGNPPVGPIGGMMPPQPGIP 398
P + K Q P+ G P G PP G G PPQ G
Sbjct: 309 ------------PQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGP-PPQGGSK 355
Query: 399 QQQGMRPPMPPHG---QYGGHHQGMPGYLPG-----AMPPYGQ--GPPMVPPYQGGPPRP 448
+ PP P G Q G + QG P G PP GQ GPP PP G P RP
Sbjct: 356 SRSARSPPGKPQGPPQQEGNNPQGPPPPAGGNPQQPQAPPAGQPQGPPR-PPQGGRPSRP 414
Query: 449 P 449
P
Sbjct: 415 P 415
Score = 88.6 bits (218), Expect = 1e-17
Identities = 106/363 (29%), Positives = 120/363 (33%), Gaps = 64/363 (17%)
Query: 128 QPQPVQPQQGYIP----PMAQPGLPPVPGAPGMPPGIPPLMPGVPPLMPGMPPVMPGMPP 183
+PQ PQ G P P +P PP G P PP P PP G P P PP
Sbjct: 77 KPQGPPPQGGNKPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPP 136
Query: 184 GLHHQRKYTQSFCGENIMMPMGGMMPPGPGIPPLMPGMPPGMPP-----------PVPRP 232
G P GG P GP PP PG P G PP P +P
Sbjct: 137 GKPQGPP------------PQGGNKPQGP--PP--PGKPQGPPPQGDNKSRSSRSPPGKP 180
Query: 233 -GIPPMTQAQAVS---APGILNRPPAPTATVPAPQPPVTKPLF--PSAGQAQAAVQGPVG 286
G PP Q PG PP P PP KP P + + P G
Sbjct: 181 QGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSQSARSPPG 240
Query: 287 TDFKPLNSTPATTTEPPKPTFPAYTQSTASTTSTTNSTAAKPAASITSKPATLTTTSATS 346
KP P +P P P + N P P + + S
Sbjct: 241 ---KPQGPPPQGGNQPQGPP-PPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGGSKSRS 296
Query: 347 KLIHPDEDISLEERRAQLP--------KYQRNLPRPGQAPIGNPPVGPIGGMMPPQPGIP 398
P + + P K Q P+ G P G PP G G PPQ G
Sbjct: 297 SRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQG-PPPQGGSK 355
Query: 399 QQQGMRPPMPPHG---QYGGHHQGMPGYLPGAMPPYGQGP--PMVPP--YQGGPPRPPMG 451
+ PP P G Q G + QG P PP G P P PP GPPRPP G
Sbjct: 356 SRSARSPPGKPQGPPQQEGNNPQGPP-------PPAGGNPQQPQAPPAGQPQGPPRPPQG 408
Query: 452 MRP 454
RP
Sbjct: 409 GRP 411
Score = 74.3 bits (181), Expect = 2e-13
Identities = 102/370 (27%), Positives = 119/370 (32%), Gaps = 71/370 (19%)
Query: 110 QDDSDEYDDDDSAASTSFQPQPVQPQQGYIPPMAQPGLPPVPGAPGMPPGIPPLMPGVPP 169
Q+ +++ ++S + + PQ PQ G +P PP P PG P G PP G P
Sbjct: 17 QNLNEDVSQEESPSLIAGNPQGAPPQGGN-----KPQGPPSP--PGKPQGPPP-QGGNQP 68
Query: 170 LMPGMPPVMPGMPPGLHHQRKYTQSFCGENIMMPMGGMMPPGPGIPPLMPGMPPGMPP-- 227
P PP P PP P GG P GP PP PG P G PP
Sbjct: 69 QGPPPPPGKPQGPP-------------------PQGGNKPQGP--PP--PGKPQGPPPQG 105
Query: 228 --------PVPRP-GIPPMTQAQAVSAP---GILNRPPAPTATVPAPQPPVTKPLFP--S 273
P +P G PP Q P G PP P PP KP P
Sbjct: 106 DKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQ 165
Query: 274 AGQAQAAVQGPVGTDFKPLNSTPATTTEPPKPTFPAYTQSTASTTSTTNSTAAKPAASIT 333
+ + P G KP P +P P P P
Sbjct: 166 GDNKSRSSRSPPG---KPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQ 222
Query: 334 SKPATLTTTSATSKLIHPDEDISLEERRAQLPKYQRNLPRPGQAPIGNPPVGPIGGMMPP 393
P P D + R+ K Q P+ G P G PP P PP
Sbjct: 223 GPP--------------PQGDNKSQSARSPPGKPQGPPPQGGNQPQGPPPP-PGKPQGPP 267
Query: 394 QPGIPQQQGMRPPMPPHGQ--YGGHHQGMPGYLPGAMPPYGQGPPMVPPYQGGPPRPPMG 451
G + QG PP P G GG PG QGPP Q P PP G
Sbjct: 268 PQGGNKPQGPPPPGKPQGPPPQGGSKSRSSRSPPGK----PQGPPPQGGNQPQGPPPPPG 323
Query: 452 MRPPVMSQGG 461
QGG
Sbjct: 324 KPQGPPPQGG 333
Score = 44.3 bits (103), Expect = 2e-04
Identities = 45/136 (33%), Positives = 54/136 (39%), Gaps = 18/136 (13%)
Query: 344 ATSKLIHPDEDISLEERRAQL-------PKYQRNLPRPGQAPIGNPP-VGPIGGMMP--- 392
A S + +ED+S EE + + P N P+ +P G P P GG P
Sbjct: 12 ALSSAQNLNEDVSQEESPSLIAGNPQGAPPQGGNKPQGPPSPPGKPQGPPPQGGNQPQGP 71
Query: 393 -PQPGIPQ----QQGMRP--PMPPHGQYGGHHQGMPGYLPGAMPPYGQGPPMVPPYQGGP 445
P PG PQ Q G +P P PP G QG P + P QGPP Q
Sbjct: 72 PPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQG 131
Query: 446 PRPPMGMRPPVMSQGG 461
P PP G QGG
Sbjct: 132 PPPPPGKPQGPPPQGG 147
>gi|163965366 nascent polypeptide-associated complex alpha subunit
isoform a [Homo sapiens]
Length = 2078
Score = 83.2 bits (204), Expect = 5e-16
Identities = 96/373 (25%), Positives = 119/373 (31%), Gaps = 49/373 (13%)
Query: 123 ASTSFQPQPVQPQQGYIPPMAQPGLPPVPGAPGMPPGIPPLMPGVPPLM---------PG 173
A+ S + P P P P P GAP P PP G P P
Sbjct: 978 ATPSPKGAPTPPAATPPSPKGGPATPSPKGAPTPPAVTPPSPKGSPAATPFPKGASTPPA 1037
Query: 174 MPPVMPGMPPGLHHQRKYTQSFCGENIMMPMGG--------------MMPPGPGIPPLMP 219
P P P K + + P GG PP P P P
Sbjct: 1038 ATPPSPKGSPAATPLPKGAPTTPAATLPSPKGGPATPSLKGAPTPPAATPPSPKGGPATP 1097
Query: 220 G-----MPPGMPPPVPRPGIPPMTQAQAVSAPGILNRPPAPTATVPAPQP---PVTKPLF 271
MPP PP P+ G+ A + P PP+P + P P P T
Sbjct: 1098 SPKGAPMPPAATPPSPKGGLATPPHKGAPTTPAA--TPPSPKGGLATPPPKGAPTTPAAT 1155
Query: 272 PSAGQAQAAVQGPVGTDFKPLNSTP------ATTTEPPKPTFPAYTQSTAS---TTSTTN 322
P + + A P G P + P AT + PT PA T + T +
Sbjct: 1156 PPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPK 1215
Query: 323 STAAKPAASITSKPATLTTTSATSKLIHPDEDISLEERRAQLPKYQRNLPRPGQAPIGNP 382
PAA+ S L T S P + P + P P P P
Sbjct: 1216 GAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGPATPP-PKGAPTP---PAATP 1271
Query: 383 PVGPIGGMMPPQPGIPQQQGMRPPMPPHGQYGGHHQGMPGYLPGAMPPYGQGPPMVPPYQ 442
P G PP G P + PP P G +G P P A PP +G P PP +
Sbjct: 1272 PSLKGGLATPPHKGAPNPAVVTPPSPKGGPATSPPKGAP-TPPAATPPSPKGSPGTPPPK 1330
Query: 443 GGPPRPPMGMRPP 455
G P P + PP
Sbjct: 1331 GAP--TPPAVTPP 1341
Score = 81.6 bits (200), Expect = 1e-15
Identities = 94/351 (26%), Positives = 113/351 (32%), Gaps = 58/351 (16%)
Query: 121 SAASTSFQPQPVQPQQGYIP-PMAQPGLPPVP-GAPGMPPGIPPLMPGVP--PLMPGMPP 176
S A+T F P P P P P+P GAP P P G P P + G P
Sbjct: 1022 SPAATPFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPSPKGGPATPSLKGAPT 1081
Query: 177 VMPGMPPGLHHQRKYTQSFCGENIMMPMGGMMPPGPGIPPLMPGMPPGMPPPVPRPGIPP 236
PP P GG P P P MPP PP P+ G+
Sbjct: 1082 PPAATPPS------------------PKGGPATPSPKGAP----MPPAATPPSPKGGLAT 1119
Query: 237 MTQAQAVSAPGILNRPPAPTATVPAPQP---PVTKPLFPSAGQAQAAVQGPVGTDFKPLN 293
A + P PP+P + P P P T P + + A P G
Sbjct: 1120 PPHKGAPTTPAAT--PPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPPPKGAP----- 1172
Query: 294 STPATTTEPPKPTFPAYTQSTASTTSTTNSTAAKPAASITSKPATLTTTSATSKLIHPDE 353
+TPA T PK + A TT + K + S TT +AT
Sbjct: 1173 TTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPS----- 1227
Query: 354 DISLEERRAQLPKYQRNLPRPGQAPI---GNPPVGPIGGMMPPQPGIPQQQGMRPPMPPH 410
PK P P AP PP G PP G P PP
Sbjct: 1228 -----------PKGGLATPSPKGAPTTPAATPPSPKGGPATPPPKGAPTPPAATPPSLKG 1276
Query: 411 GQYGGHHQGMPGYLPGAM-PPYGQGPPMVPPYQGGPPRPPMGMRPPVMSQG 460
G H+G P P + PP +G P P +G P P P S G
Sbjct: 1277 GLATPPHKGAPN--PAVVTPPSPKGGPATSPPKGAPTPPAATPPSPKGSPG 1325
Score = 73.9 bits (180), Expect = 3e-13
Identities = 88/349 (25%), Positives = 107/349 (30%), Gaps = 37/349 (10%)
Query: 124 STSFQPQPVQPQQGYIPPMAQPGLPPVPGA--PGMPPGI--PPLMPGVPPLM----PGMP 175
S SFQ P + P P P P A P P G+ PP P ++ P
Sbjct: 840 SLSFQGSKDSPATTHSPTPPSPKGAPTPSAVTPLSPKGVTLPPKETPTPSVVNLPFPKEG 899
Query: 176 PVMPGMPPGLHHQRKYTQSFCGENIMMPMGGMMPPGPGIPPLMPGMPPGMPPPVPRPGIP 235
P P + P G P P P P P P P P
Sbjct: 900 PATPAPKQAPALSMTSSSPKKARATPAPKGIPASPSPKGAPTPPAATPPSPKGGPATPSP 959
Query: 236 PMTQAQAVSAPGILNRPPAPTATVPAPQPPVTKPLFPSAGQAQAAVQG------------ 283
+ P PA + AP PP P P G A + +G
Sbjct: 960 KWAPTPPAATPPSPKGGPATPSPKGAPTPPAATPPSPKGGPATPSPKGAPTPPAVTPPSP 1019
Query: 284 ---PVGTDFKPLNSTPATTTEPPKPTFPAYTQSTASTTSTTNSTAAKPAASITSKPATLT 340
P T F STP T P PA T +T +T P PAT +
Sbjct: 1020 KGSPAATPFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPSPKGG----PATPS 1075
Query: 341 TTSATSKLIHPDEDISLEERRAQLPKYQRNLPRPGQAPIGNPPVGPIGGMM-PPQPGIPQ 399
A + P + + P P P PP P GG+ PP G P
Sbjct: 1076 LKGAPT----PPAATPPSPKGGPATPSPKGAPMP---PAATPP-SPKGGLATPPHKGAPT 1127
Query: 400 QQGMRPPMPPHGQYGGHHQGMPGYLPGAMPPYGQGPPMVPPYQGGPPRP 448
PP P G +G P P A PP +G PP +G P P
Sbjct: 1128 TPAATPPSPKGGLATPPPKGAP-TTPAATPPSPKGGLATPPPKGAPTTP 1175
Score = 70.1 bits (170), Expect = 4e-12
Identities = 98/376 (26%), Positives = 121/376 (32%), Gaps = 63/376 (16%)
Query: 140 PPMAQPGL--PPVPGAPGMPPGIPPLMPG-----VPPLMPGMPPVMPGMPPG--LHHQRK 190
PP + GL PP GAP P PP G P P P P P G K
Sbjct: 1156 PPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPK 1215
Query: 191 YTQSFCGENIMMPMGGMMPP----GPGIPPLMPGMPPGMPPPVPRPGIPPMTQAQAVSAP 246
+ P GG+ P P P P P G P P G P A S
Sbjct: 1216 GAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGPATPPPKGAPTPPAATPPSLK 1275
Query: 247 GILNRPPAPTATVPAPQPPVTKPLFPSAGQAQAAVQG----PVGTDFKPLNS-------- 294
G L PP AP P V P P G A + +G P T P S
Sbjct: 1276 GGLATPPHK----GAPNPAVVTPPSPKGGPATSPPKGAPTPPAATPPSPKGSPGTPPPKG 1331
Query: 295 ---TPATTTEPPK--PTFPAYTQST--ASTTSTTNSTAAKPAASITSKPATLTTTSATSK 347
PA T PK PT PA T S+ TT ++ PAA+ + K T + +
Sbjct: 1332 APTPPAVTPPSPKGTPTLPATTPSSKGGPTTPSSKEGPTPPAATPSHKGGPAMTPPSPKR 1391
Query: 348 ---LIHPDED------ISLEERRA-QLPKYQRNLPRPGQAPIGNPPVGPI---------- 387
+ P D I L ++A P + P + + P V P+
Sbjct: 1392 GPAIPSPKGDPTSPAVIPLSPKKAPATPVTREGAATPSKGDLTPPAVTPVSLKKAPATSA 1451
Query: 388 ---GGMMPPQPGIPQQQGMRPPMP--PHGQYGGHHQGMPGYLPGAMPPYGQG--PPMVPP 440
G P G P + PP P P P P P G P ++P
Sbjct: 1452 PKGGPATPSSKGDPTLPAVTPPSPKEPPAPKQVATSSSPKKAPATPAPMGAPTLPAVIPS 1511
Query: 441 YQGGPPRPPMGMRPPV 456
P P R P+
Sbjct: 1512 SPKEVPATPSSRRDPI 1527
Score = 68.6 bits (166), Expect = 1e-11
Identities = 91/357 (25%), Positives = 116/357 (32%), Gaps = 61/357 (17%)
Query: 131 PVQPQQGYIPPMAQPGLPPVPGAPGMPPGIPPLMPGVPPLMPGMPPVMPGMPPGLHHQRK 190
P P P PG PP GAP PP + P P P +P P G P +
Sbjct: 1310 PTPPAATPPSPKGSPGTPPPKGAP-TPPAVTPPSPKGTPTLPATTPSSKGGPTTPSSKEG 1368
Query: 191 YTQSFCGENIMMPMGG--MMPPGPGIPPLMPGMPPGMP--------PPVPRPGIPPMTQA 240
T + GG M PP P P +P P G P P P P +
Sbjct: 1369 PTPPAATPS---HKGGPAMTPPSPKRGPAIPS-PKGDPTSPAVIPLSPKKAPATPVTREG 1424
Query: 241 QAVSAPGILNRP---PAPTATVPAPQPPVTKPLFPSA-GQAQAAVQGPVGTDFKPLNSTP 296
A + G L P P PA P P PS+ G P P
Sbjct: 1425 AATPSKGDLTPPAVTPVSLKKAPATSAPKGGPATPSSKGDPTLPAVTPPSPKEPPAPKQV 1484
Query: 297 ATTTEPPK----------PTFPAYTQSTASTTSTTNST---AAKPAASITSK--PATLTT 341
AT++ P K PT PA S+ T S+ P A++ SK PATL
Sbjct: 1485 ATSSSPKKAPATPAPMGAPTLPAVIPSSPKEVPATPSSRRDPIAPTATLLSKKTPATLAP 1544
Query: 342 TSATSKLIHPDEDISLEERRAQLPKYQRNLPRPGQAPIGNPP-VGPI---GGMMPPQ--- 394
A LI P + ++ +P + P +PP V P G P +
Sbjct: 1545 KEA---LIPPAMTVPSPKKTPAIPTPKEAPATPSSKEASSPPAVTPSTYKGAPSPKELLI 1601
Query: 395 -PGIPQQQGMRPPMPPHGQYGGHHQGMPGYLPGAMPPYGQGPPMVPPYQGGPPRPPM 450
P + P P P PP + P P +G P PP+
Sbjct: 1602 PPAVTSPSPKEAPTP----------------PAVTPPSPEKGPATPAPKGTPTSPPV 1642
Score = 58.5 bits (140), Expect = 1e-08
Identities = 99/427 (23%), Positives = 142/427 (33%), Gaps = 102/427 (23%)
Query: 123 ASTSFQPQPVQPQQGYIPPMAQPGLPPVP------GAPGMPPGIPPLM--PGVPPLMPGM 174
A+ S + P P PP P PP P +P P P M P +P ++P
Sbjct: 1457 ATPSSKGDPTLP--AVTPP--SPKEPPAPKQVATSSSPKKAPATPAPMGAPTLPAVIPSS 1512
Query: 175 PPVMPGMPPGLHHQRKYTQSFCGENI---MMPMGGMMPPGPGIPPLMPGMPPGMPPPVPR 231
P +P P T + + + P ++PP +P P P +P P
Sbjct: 1513 PKEVPATPSSRRDPIAPTATLLSKKTPATLAPKEALIPPAMTVPS--PKKTPAIPTPKEA 1570
Query: 232 PGIPPMTQAQAVSA-----------PGILNRPPAPTATVP--APQPPVTKPLFPSAGQAQ 278
P P +A + A P L PPA T+ P AP PP P P G A
Sbjct: 1571 PATPSSKEASSPPAVTPSTYKGAPSPKELLIPPAVTSPSPKEAPTPPAVTPPSPEKGPAT 1630
Query: 279 AAVQG-----PVG-TDFKPLNSTPATTT----------------------------EPPK 304
A +G PV + K ++PA+ T P
Sbjct: 1631 PAPKGTPTSPPVTPSSLKDSPTSPASVTCKMGATVPQASKGLPAKKGPTALKEVLVAPAP 1690
Query: 305 PTFPAYTQSTASTTSTTNSTAAKP------AASITSK-------PATLTTTSATSKLIHP 351
+ P T T T S+A P +A SK PA L S
Sbjct: 1691 ESTPIITAPTRKGPQTKKSSATSPPICPDPSAKNGSKGPLSTVAPAPLLPVQKDSSKTAK 1750
Query: 352 DEDISLE--------ERRAQLP----KYQRNLPRPGQAPIGNPPVGPIGGMMPPQPGIPQ 399
+D S E +A P +++ LP+P A + P P+ + P P
Sbjct: 1751 GKDASHSPKGPLAPPESKASTPLTAAAFEKVLPKPESASVSAAPSPPVSLPLAPSP---- 1806
Query: 400 QQGMRPPMPPHGQYGGHHQGMPGYLPG-AMPPYGQGP--PMVP--PYQGGPPRPPMGMRP 454
P +PP Q+ G+ P + P + P++P P GG P + +
Sbjct: 1807 ----VPTLPPKQQFLPSSPGLVLESPSKPLAPADEDELLPLIPPEPISGGVPFQSVLVNM 1862
Query: 455 PVMSQGG 461
P G
Sbjct: 1863 PTPKSAG 1869
Score = 48.9 bits (115), Expect = 1e-05
Identities = 64/271 (23%), Positives = 84/271 (30%), Gaps = 50/271 (18%)
Query: 221 MPPGMPPPVPRPGIPPM-TQAQAVSAPGILNRPPAPTATVPAPQPPVTKPLFPSAGQAQA 279
+ P +P VP P +PP T GI + +A P P P S A A
Sbjct: 726 LAPEIPKSVPSPSLPPAGTPPGTKKVDGISH----TSALAPVASSPKECPTEDSGASATA 781
Query: 280 AVQG----------PVGTDFKPLNSTPATTTEPPKPTFP--------------------- 308
+ +G P+G P P T P P
Sbjct: 782 SSKGTLTYLADSPSPLGVSVSPQTKRPPTKKGSAGPDTPIGNLSSPVSPVEASFLPENSL 841
Query: 309 AYTQSTASTTSTTNSTAAKPAASITSKPATLTTTSATSKLIHPDEDISLEERRAQLPKYQ 368
++ S S +T + T P + T P+ +T S + P E + PK
Sbjct: 842 SFQGSKDSPATTHSPTPPSPKGAPT--PSAVTPLSPKGVTLPPKETPTPSVVNLPFPKEG 899
Query: 369 RNLPRPGQAPI----------GNPPVGPIGGMMPPQP-GIPQQQGMRPPMPPHGQYGGHH 417
P P QAP P G P P G P PP P G
Sbjct: 900 PATPAPKQAPALSMTSSSPKKARATPAPKGIPASPSPKGAPTPPAATPPSPKGGPATPSP 959
Query: 418 QGMPGYLPGAMPPYGQGPPMVPPYQGGPPRP 448
+ P P A PP +G P P +G P P
Sbjct: 960 KWAP-TPPAATPPSPKGGPATPSPKGAPTPP 989
Score = 35.8 bits (81), Expect = 0.084
Identities = 34/137 (24%), Positives = 46/137 (33%), Gaps = 18/137 (13%)
Query: 212 PGIPPLMPGMPPGMPPPVPRPGIPPMTQAQAVSAPGILNRPPAPTATVPAPQPPVTKPLF 271
P I P + G P P P Q + P +L PP+ ++ P+
Sbjct: 121 PMIAPTLKGTPSSSAPLALVALAPHSVQKSSAFPPNLLTSPPSVAVAESGSVITLSAPIA 180
Query: 272 PSAGQAQAAVQGPVGTDFKPLNSTPATTTEPPKPTFPAYTQSTASTTSTTNSTAAKPAAS 331
PS + LN P+ PK T S ST P AS
Sbjct: 181 PSEPKTN-------------LNKVPSEVVPNPKG-----TPSPPCIVSTVPYHCVTPMAS 222
Query: 332 ITSKPATLTTTSATSKL 348
I S A+L T+ T+ L
Sbjct: 223 IQSGVASLPQTTPTTTL 239
Score = 35.8 bits (81), Expect = 0.084
Identities = 72/338 (21%), Positives = 104/338 (30%), Gaps = 64/338 (18%)
Query: 123 ASTSFQPQPVQPQQGYIPPMAQ--PGLPPVPGAPGMPPGIPPLMPGVPPLMPGMPPVMPG 180
A TS P+ PP + P P G P PP P + P
Sbjct: 1604 AVTSPSPKEAPTPPAVTPPSPEKGPATPAPKGTPTSPPVTPSSLKDSP------------ 1651
Query: 181 MPPGLHHQRKYTQSFCGENIMMPMGGMMPPGPGIPPLMPGMPPGMPPPVPRPGIPPMTQA 240
P G +P G+P + G + +
Sbjct: 1652 --------------------TSPASVTCKMGATVPQASKGLP-------AKKGPTALKEV 1684
Query: 241 QAVSAPGILNRPPAPTATVPAPQPPVTKPLFPSAGQAQAAVQGPVGTDFKPLN-STPATT 299
AP P T P + P TK +A P+ D N S +
Sbjct: 1685 LVAPAP-----ESTPIITAPTRKGPQTK--------KSSATSPPICPDPSAKNGSKGPLS 1731
Query: 300 TEPPKPTFPAYTQSTASTTSTTNSTAAK-PAASITSKPATLTTTSATSKLIHPDEDISLE 358
T P P P S+ + S + K P A SK +T T +A K++ E S+
Sbjct: 1732 TVAPAPLLPVQKDSSKTAKGKDASHSPKGPLAPPESKASTPLTAAAFEKVLPKPESASV- 1790
Query: 359 ERRAQLPKYQRNLPRPGQAPIGNPPVGPIGGMMPPQPGIPQQQGMRPPMPPHGQYGGHHQ 418
+ P +LP AP P + P +P PG+ + + P+ P +
Sbjct: 1791 ---SAAPSPPVSLP---LAPSPVPTLPPKQQFLPSSPGLVLESPSK-PLAPADEDELLPL 1843
Query: 419 GMPGYLPGAMPPYGQGPPMVPPYQGGPPRPPMGMRPPV 456
P + G +P M P G P P + PV
Sbjct: 1844 IPPEPISGGVPFQSVLVNMPTPKSAGIPVPTPSAKQPV 1881
Score = 33.9 bits (76), Expect = 0.32
Identities = 50/218 (22%), Positives = 74/218 (33%), Gaps = 38/218 (17%)
Query: 142 MAQPGLPPVPGAPGMPPGIPPLMPGVPPLMPGMPPVMPGMPPGLHHQRKYTQSFCGENIM 201
+ +P V AP PP PL P P +P +P P
Sbjct: 1782 LPKPESASVSAAPS-PPVSLPLAPSPVPTLPPKQQFLPSSP------------------- 1821
Query: 202 MPMGGMMPPGPGIPPLMPGMPPGMPPPVPRPGIPPMTQAQAVSAPGILNRPPAPTATVPA 261
G++ P PL P + P +P I Q+V ++N P +A +P
Sbjct: 1822 ----GLVLESPS-KPLAPADEDELLPLIPPEPISGGVPFQSV----LVNMPTPKSAGIPV 1872
Query: 262 PQP----PVTKPLFPSAGQAQAAVQGPVGTDFKPLNSTPATTTEPPKPTFPAYTQSTAST 317
P P PVTK S ++ + P + + +ST ATT + + S
Sbjct: 1873 PTPSAKQPVTKNNKGSGTESDSDESVP---ELEEQDSTQATTQQAQLAAAAEIDEEPVS- 1928
Query: 318 TSTTNSTAAKPAASITSKPATLTTTSATSKLIHPDEDI 355
S + K A SK T T I ++I
Sbjct: 1929 -KAKQSRSEKKARKAMSKLGLRQVTGVTRVTIRKSKNI 1965
Score = 30.8 bits (68), Expect = 2.7
Identities = 31/144 (21%), Positives = 51/144 (35%), Gaps = 17/144 (11%)
Query: 218 MPGMPPGMPPPVPRPGIPPMTQAQAVSA----PGILNRPPAPTAT-------------VP 260
+P +P P + PM+ A +V+A PG PP A P
Sbjct: 9 VPATEQELPQPQAETAVLPMSSALSVTAALGQPGPTLPPPCSPAPQQCPLSAANQASPFP 68
Query: 261 APQPPVTKPLFPSAGQAQAAVQGPVGTDFKPLNSTPATTTEPPKPTFPAYTQSTASTTST 320
+P + PL Q+ + P+GT + P P P A + T
Sbjct: 69 SPSTIASTPLEVPFPQSSSGTALPLGTAPEAPTFLPNLIGPPISPAALALASPMIAPTLK 128
Query: 321 TNSTAAKPAASITSKPATLTTTSA 344
+++ P A + P ++ +SA
Sbjct: 129 GTPSSSAPLALVALAPHSVQKSSA 152
Score = 30.4 bits (67), Expect = 3.5
Identities = 37/190 (19%), Positives = 62/190 (32%), Gaps = 38/190 (20%)
Query: 232 PGIPPMTQAQAVSAPGILNR------PPAPTAT-----------VPAPQPPVTKPLFPSA 274
P + P+ QA ++P + P +P AT + P +T PL ++
Sbjct: 557 PTVLPLVQAAPKNSPSFQSTSSSPEIPLSPEATLAKKSLGEPLPIGKPASSMTSPLGVNS 616
Query: 275 GQAQAAVQGPVGTD-----FKPLNSTPATTTEPPKPTFPAYTQSTASTTSTTNSTAAKP- 328
+ G D K TP P + PA T + ++T +T A P
Sbjct: 617 SASVIKTDSYAGPDSAGPLLKSSLITPTVAAFPLESADPAGVAPTTAKGTSTYTTTASPF 676
Query: 329 ---------------AASITSKPATLTTTSATSKLIHPDEDISLEERRAQLPKYQRNLPR 373
++T+ P T + P + P+ +++P
Sbjct: 677 LEGTVSLAPKNHPVKEGTLTTLPLVPTASENCPVAPSPQNTCAPLATLVLAPEIPKSVPS 736
Query: 374 PGQAPIGNPP 383
P P G PP
Sbjct: 737 PSLPPAGTPP 746
>gi|21361376 splicing factor 3a, subunit 2 [Homo sapiens]
Length = 464
Score = 82.8 bits (203), Expect = 6e-16
Identities = 99/328 (30%), Positives = 116/328 (35%), Gaps = 99/328 (30%)
Query: 141 PMAQPGLPPVPGAPGMPPGIPPLMPGVPPLMPGMPPVMPGMPPGLHHQRKYTQSFCGENI 200
P A P LP P PP PPLM G+PP P +P +P PPG
Sbjct: 217 PPAPPSLPAGPPGVKRPP--PPLMNGLPP-RPPLPESLPPPPPG---------------- 257
Query: 201 MMPMGGMMPPGPGIPPLMPGMPPGMPPPVPRPGIPPMTQAQAVSAPGILNRPPAPTATVP 260
+P+ M P GP P P PP +PPP P G+ P A V P PPAP P
Sbjct: 258 GLPLPPMPPTGPA--PSGPPGPPQLPPPAP--GVHP--PAPVVHPPASGVHPPAPGVHPP 311
Query: 261 AP--QPPVTKPLFPSAGQAQAAVQGPVGTDFKPLNSTPATTTEPPKPTFPAYTQSTASTT 318
AP PP P++G PA PP P
Sbjct: 312 APGVHPPAPGVHPPTSGV-----------------HPPAPGVHPPAP------------- 341
Query: 319 STTNSTAAKPAASITSKPATLTTTSATSKLIHPDEDISLEERRAQLPKYQRNLPRPGQAP 378
P A PA +HP P PG P
Sbjct: 342 ------GVHPPAPGVHPPA---------PGVHP--------------------PAPGVHP 366
Query: 379 IGNPPVGP-IGGMMPPQPGI-PQQQGMRPPMP-PHGQYGGHHQGMPGYLPGAMPPYGQGP 435
+ V P G+ P P + PQ G+ PP P H Q G H PG P A P P
Sbjct: 367 PPSAGVHPQAPGVHPAAPAVHPQAPGVHPPAPGMHPQAPGVHPQPPGVHPSA-PGVHPQP 425
Query: 436 PMVPPYQGG--PPRP-PMGMRPPVMSQG 460
P V P G PP P P +RPP+ S+G
Sbjct: 426 PGVHPSNPGVHPPTPMPPMLRPPLPSEG 453
Score = 77.4 bits (189), Expect = 3e-14
Identities = 51/155 (32%), Positives = 64/155 (41%), Gaps = 32/155 (20%)
Query: 134 PQQGYIPPMAQPGLPPVPGAPGMPPGIPPLMPGVPPLMPGMPPVMPGMPPGLHHQRKYTQ 193
P G PP + PP PG PG+ P PGV P PG+ P PG+ P
Sbjct: 318 PAPGVHPPTSGVH-PPAPGVHPPAPGVHPPAPGVHPPAPGVHPPAPGVHP---------- 366
Query: 194 SFCGENIMMPMGGMMPPGPGIPPLMPGM---PPGMPPPVP-----RPGIPPMTQAQAVSA 245
P G+ P PG+ P P + PG+ PP P PG+ P SA
Sbjct: 367 --------PPSAGVHPQAPGVHPAAPAVHPQAPGVHPPAPGMHPQAPGVHPQPPGVHPSA 418
Query: 246 PGILNRPPA-----PTATVPAPQPPVTKPLFPSAG 275
PG+ +PP P P P PP+ +P PS G
Sbjct: 419 PGVHPQPPGVHPSNPGVHPPTPMPPMLRPPLPSEG 453
Score = 77.0 bits (188), Expect = 3e-14
Identities = 86/301 (28%), Positives = 107/301 (35%), Gaps = 83/301 (27%)
Query: 140 PPMAQPGLPPVP----GAPGMPPG---IPPLMP-GVPPLMPGMPPVMPGMPPGLHHQRKY 191
PP GLPP P P PPG +PP+ P G P P PP +P PG+H
Sbjct: 234 PPPLMNGLPPRPPLPESLPPPPPGGLPLPPMPPTGPAPSGPPGPPQLPPPAPGVHPPAPV 293
Query: 192 TQSFCGENIMMPMGGMMPPGPGIPPLMPGMPPGMPPPVPRPGIPPMTQAQAVSAPGILNR 251
+ P G+ PP PG+ P PG+ P P PG+ P T APG+
Sbjct: 294 --------VHPPASGVHPPAPGVHPPAPGVHP------PAPGVHPPTSGVHPPAPGV--H 337
Query: 252 PPAPTATVPAP--QPPVTKPLFPSAGQAQAAVQGPVGTDFKPLNSTPATTTEPPKP-TFP 308
PPAP PAP PP P+ G ++ P+ P P P
Sbjct: 338 PPAPGVHPPAPGVHPPAPGVHPPAPG----------------VHPPPSAGVHPQAPGVHP 381
Query: 309 AYTQSTASTTSTTNSTAAKPAASITSKPATLTTTSATSKLIHPDEDISLEERRAQLPKYQ 368
A + A P A PA A +HP Q P
Sbjct: 382 A-------------APAVHPQAPGVHPPAPGMHPQAPG--VHP-----------QPPGVH 415
Query: 369 RNLPRPGQAPIGNPPVGPIGGMMPPQPGIPQQQGMRPPMPPHGQYGGHHQGMPGYLPGAM 428
+ P P G P P G+ PP P P +RPP+P G PG +P
Sbjct: 416 PSAPGVHPQPPGVHPSNP--GVHPPTPMPPM---LRPPLPSEG---------PGNIPPPP 461
Query: 429 P 429
P
Sbjct: 462 P 462
Score = 60.8 bits (146), Expect = 2e-09
Identities = 43/126 (34%), Positives = 51/126 (40%), Gaps = 21/126 (16%)
Query: 134 PQQGYIPPMAQPGLPPVPGAPGMPPGIPPLMPGVPPLMPGMPPVMPGM---PPGLHHQRK 190
P G PP PP G PG+ P P V P PG+ P PGM PG+H Q
Sbjct: 353 PAPGVHPPAPGVHPPPSAGVHPQAPGVHPAAPAVHPQAPGVHPPAPGMHPQAPGVHPQPP 412
Query: 191 YTQSFCGENIMMPMGGMMPPGPGIPPLMPGMPPGMPPPVPRPGIPPMTQAQAVS-APGIL 249
G+ P PG+ P PG+ P P P +PPM + S PG
Sbjct: 413 ---------------GVHPSAPGVHPQPPGVHPSNPGVHPPTPMPPMLRPPLPSEGPG-- 455
Query: 250 NRPPAP 255
N PP P
Sbjct: 456 NIPPPP 461
Score = 56.6 bits (135), Expect = 5e-08
Identities = 39/111 (35%), Positives = 47/111 (42%), Gaps = 29/111 (26%)
Query: 132 VQPQQGYIPPMAQPGLPPVPGAPGMPPGIPPLMPGVPPLMPGMPPVMPGM---PPGLHHQ 188
V PQ + P A P PG PG+ P PGV P PG+ P PG+ PPG+H
Sbjct: 372 VHPQAPGVHPAAPAVHPQAPGVHPPAPGMHPQAPGVHPQPPGVHPSAPGVHPQPPGVH-- 429
Query: 189 RKYTQSFCGENIMMPMGGMMPPGPGIPPLMPGMPPGMPPPVPRPG---IPP 236
P PG+ P P MPP + PP+P G IPP
Sbjct: 430 --------------------PSNPGVHPPTP-MPPMLRPPLPSEGPGNIPP 459
Score = 47.4 bits (111), Expect = 3e-05
Identities = 33/99 (33%), Positives = 39/99 (39%), Gaps = 22/99 (22%)
Query: 132 VQPQQGYIPPMAQPGLPPVPGAPGMPPGIPPLMPGVPPLMPGMPPVMPGMPPGLHHQRKY 191
V PQ + P A P PG PPG+ P PGV P PG+ P PG+ P
Sbjct: 386 VHPQAPGVHPPAPGMHPQAPGVHPQPPGVHPSAPGVHPQPPGVHPSNPGVHP-------- 437
Query: 192 TQSFCGENIMMPMGGMMPPGPGIPPLMPGMPPGMPPPVP 230
PM M+ PPL P +PPP P
Sbjct: 438 ---------PTPMPPMLR-----PPLPSEGPGNIPPPPP 462
>gi|224451135 splicing factor, arginine/serine-rich 15 isoform 3
[Homo sapiens]
Length = 1125
Score = 82.0 bits (201), Expect = 1e-15
Identities = 99/375 (26%), Positives = 129/375 (34%), Gaps = 75/375 (20%)
Query: 107 KKQQDDSDEYDDDDSAASTSFQPQPVQPQQGYIPPMAQPGLPPVPGAPGMPPGIPPLMPG 166
KK +++ + +++ + P P +P +PP+ P VP PP +PP PG
Sbjct: 635 KKPENEVAQNGGAETSHTEPVSPIP-KPLPVPVPPIPVPAPITVP-----PPQVPPHQPG 688
Query: 167 VPPLMPGMPPVMPGMPPGLHHQRKYTQSFCGENIMMPMGGMMPP--GPGIPPLMPGMPPG 224
PP++ + P P P L G+ PP GPG+P PP
Sbjct: 689 -PPVVGALQP--PAFTPPL--------------------GIPPPGFGPGVP------PPP 719
Query: 225 MPPPVPRPGIPPMTQAQAVSAPGILNRPPAPTATVPAPQ-PPVTKPLFPSAGQAQAAVQG 283
PPP RPG PM PG P P ++P P PP++ P S + A
Sbjct: 720 PPPPFLRPGFNPMHLPPGFLPPG-PPPPITPPVSIPPPHTPPISIPNLVSGARGNA---- 774
Query: 284 PVGTDFKPLNST--PATTTEPPKPTFPAYTQSTASTTSTTNSTAAKPAASITSKPATLTT 341
G K S PA T P P S + P I + +
Sbjct: 775 ESGDSVKMYGSAVPPAAPTNLPTP-------PVTQPVSLLGTQGVAPGPVIGLQAPSTGL 827
Query: 342 TSATSKLIHPDEDISLEERRAQLPKYQRNLPRPGQAPIGNPPVGPIGGMMPPQPGIPQQQ 401
A LI + Q P P PP GP G MPP
Sbjct: 828 LGARPGLIPLQRPPGMPPPHLQRFPLMPPRPMPPHMMHRGPPPGPGGFAMPP------PH 881
Query: 402 GMRPPMPPHGQY----GGHHQGMPGYLPGA-----------MPPYGQGPPMVP--PYQGG 444
GM+ P PPHG + G G PG PG P Q P P P Q
Sbjct: 882 GMKGPFPPHGPFVRPGGMPGLGGPGPGPGGPEDRDGRQQPPQQPQQQPQPQAPQQPQQQQ 941
Query: 445 PPRPPMGMRPPVMSQ 459
+PP +PP Q
Sbjct: 942 QQQPPPSQQPPPTQQ 956
Score = 70.1 bits (170), Expect = 4e-12
Identities = 99/350 (28%), Positives = 121/350 (34%), Gaps = 111/350 (31%)
Query: 120 DSAASTSFQPQPVQPQQGYIPPMAQPGLPPVPGAPGMPPGIPPLMPGVPPLMPGMPPVMP 179
+ A TS +PV P IP +PP+P P P +PP P VPP PG P V
Sbjct: 644 NGGAETS-HTEPVSP----IPKPLPVPVPPIP-VPA-PITVPP--PQVPPHQPGPPVVGA 694
Query: 180 GMPPGLHHQRKYTQSFCGENIMMPMGGMMPPG--PGIPPLMPGMPPGMPPPVPRPGIPPM 237
PP P G+ PPG PG+PP P PPP RPG PM
Sbjct: 695 LQPPAF----------------TPPLGIPPPGFGPGVPP------PPPPPPFLRPGFNPM 732
Query: 238 TQAQAVSAPGILNRPPAPTATVPAPQ-PPVTKPLFPSAGQAQAAVQGPVGTDFKPLNST- 295
PG P P ++P P PP++ P S + A G K S
Sbjct: 733 HLPPGFLPPGP-PPPITPPVSIPPPHTPPISIPNLVSGARGNAES----GDSVKMYGSAV 787
Query: 296 -PATTTEPPKPTFPAYTQSTASTTSTTNSTAAKPAASITSKPATLTTTSATSKLIHPDED 354
PA T P P ++P +L T + P
Sbjct: 788 PPAAPTNLPTPP--------------------------VTQPVSLLGTQGVA----PGPV 817
Query: 355 ISLEERRAQLPKYQRNLPRPGQAPIGNPPVGPIGGMMPPQ----PGIPQQQGMRPPMPPH 410
I L Q P RPG P+ PP GM PP P +P + PMPPH
Sbjct: 818 IGL-----QAPSTGLLGARPGLIPLQRPP-----GMPPPHLQRFPLMPPR-----PMPPH 862
Query: 411 GQYGGHHQGMPGYLPGAMPPYGQGPPMVPPYQGGPPRPPMGMRPPVMSQG 460
+ G PP G G +PP P GM+ P G
Sbjct: 863 MMHRG-------------PPPGPGGFAMPP--------PHGMKGPFPPHG 891
Score = 50.4 bits (119), Expect = 3e-06
Identities = 45/132 (34%), Positives = 49/132 (37%), Gaps = 27/132 (20%)
Query: 131 PVQPQQGYIPPMAQPGLPPVPGAPGMPPGIPPLMPGVPPLMPGMPPVMPGMPPGLHHQRK 190
P+ P + P M G PP PG MPP P M G P P P V PG PGL
Sbjct: 852 PLMPPRPMPPHMMHRGPPPGPGGFAMPP--PHGMKG--PFPPHGPFVRPGGMPGL----- 902
Query: 191 YTQSFCGENIMMPMGGMMPPGPGIPPLMPG--MPPGMPPPVPRPGIPPMTQAQAVSAPGI 248
G PGPG P G PP P P+P P Q Q P
Sbjct: 903 ---------------GGPGPGPGGPEDRDGRQQPPQQPQQQPQPQAPQQPQQQQQQQPPP 947
Query: 249 LNRPPAPTATVP 260
+PP PT P
Sbjct: 948 SQQPP-PTQQQP 958
Score = 38.1 bits (87), Expect = 0.017
Identities = 57/242 (23%), Positives = 75/242 (30%), Gaps = 61/242 (25%)
Query: 224 GMPPPVPRPGIPPMTQAQAVSAPGILNRPPAPTATVPAPQPPVTK-------------PL 270
G PPP + P TQA S P + P + A T+ P
Sbjct: 153 GSPPPPVKVSSEPPTQATPNSVPAVPQLPSSDAFAAVAQLFQTTQGQQLQQILQTFQQPP 212
Query: 271 FPSAGQAQAAVQGPVGTDFKPLNSTPATTTEPPKPTFPAYTQSTA--------------- 315
P + AV V L +TP +E K FP Q TA
Sbjct: 213 KPQSPALDNAVMAQVQAITAQLKTTPTQPSEQ-KAAFPPPEQKTAFDKKLLDRFDYDDEP 271
Query: 316 -----------STTSTTNSTAAKPAASITSKPATLTTTSATSKLIHPDEDISLEERRAQL 364
+ +TT AA P A + PA +A+ P Q
Sbjct: 272 EAVEESKKEDTTAVTTTAPAAAVPPAPTATVPAAAAPAAASPP--PPQAPFGFPGDGMQQ 329
Query: 365 PKYQRNL---------------PRPGQAPIGNPPVG--PIGGMMPPQPGIPQQQGMRPPM 407
P Y ++ P Q P+ PP G P G++P P P Q + PP
Sbjct: 330 PAYTQHQNMDQFQPRMMGIQQDPMHHQVPL--PPNGQMPGFGLLPTPPFPPMAQPVIPPT 387
Query: 408 PP 409
PP
Sbjct: 388 PP 389
Score = 38.1 bits (87), Expect = 0.017
Identities = 44/149 (29%), Positives = 58/149 (38%), Gaps = 21/149 (14%)
Query: 98 EQKTQESQKKKQQDDSDEYDD-------DDSAASTSFQPQPVQPQQ--GYIPPMAQPGL- 147
EQKT +K + D D+ + +D+ A T+ P P +P A P
Sbjct: 252 EQKTAFDKKLLDRFDYDDEPEAVEESKKEDTTAVTTTAPAAAVPPAPTATVPAAAAPAAA 311
Query: 148 -PPVPGAPGMPPGIPPLMPGVPPL--MPGMPPVMPGMPPG-LHHQRKYTQSFCGENIMMP 203
PP P AP PG P M P M G+ +HHQ N MP
Sbjct: 312 SPPPPQAPFGFPGDGMQQPAYTQHQNMDQFQPRMMGIQQDPMHHQVPLPP-----NGQMP 366
Query: 204 MGGMMPPGPGIPPLMPGMPPGMPPPVPRP 232
G++P P P P +PP PPV +P
Sbjct: 367 GFGLLPTPPFPPMAQPVIPP--TPPVQQP 393
>gi|150170670 piccolo isoform 2 [Homo sapiens]
Length = 4935
Score = 80.1 bits (196), Expect = 4e-15
Identities = 100/375 (26%), Positives = 128/375 (34%), Gaps = 55/375 (14%)
Query: 99 QKTQESQKKKQQDDSDEYDDDDSAASTSFQPQPVQPQQGYIPPMAQPGLPPVPGAPGMPP 158
+ +QE KKQ+ E + Q QP +P IP PG P+ G P
Sbjct: 183 EASQEETTKKQKVVQKEQGKPEGIIKPPLQQQPPKP----IPKQQGPGRDPLQ-QDGTPK 237
Query: 159 GIPPLMPGVPPLMP---GMPPVMPGMPPGLHHQRKYTQSFCGENIMMPMGGMMPPGPGIP 215
I P P G P P P H + Q + G +
Sbjct: 238 SISSQQPEKIKSQPPGTGKPIQGPTQTPQTDHAKLPLQRDASRP--QTKQADIVRGESVK 295
Query: 216 PLMPGMPPGMPP-PVPRPGIPPMTQAQAVSAPGILNRPPAPTATVPAPQPPVTKPLFPSA 274
P +P P PP P PG PP Q PG P P A PA +TKPL
Sbjct: 296 PSLPS--PSKPPIQQPTPGKPPAQQ------PGHEKSQPGP-AKPPAQPSGLTKPLAQQP 346
Query: 275 GQAQAAVQGPVGTDFKPLNSTPATTTEPPKPTFPAYTQSTASTTSTTNSTAAKPAASITS 334
G + VQ P TT P +P PA + A T + ++ +P +
Sbjct: 347 GTVKPPVQ------------PPGTTKPPAQPLGPA--KPPAQQTGSEKPSSEQPGPKALA 392
Query: 335 KPATLTTTSATSK--LIHPDEDISLEERRAQLPKYQRNLPRPGQAPIGNPPVGPIGGMMP 392
+P + T A P + + + AQ P Q PG P P P G +P
Sbjct: 393 QPPGVGKTPAQQPGPAKPPTQQVGTPKPLAQQPGLQSPAKAPG--PTKTPVQQPGPGKIP 450
Query: 393 PQ---PGIPQQQGMRPPMPPHGQYGGHHQGMPGYLPGAMPPYGQGPPMVPPYQGGPPRPP 449
Q PG Q P PP +PG P PP GP PP Q G +PP
Sbjct: 451 AQQAGPGKTSAQQTGPTKPP--------SQLPG--PAKPPPQQPGPAKPPPQQPGSAKPP 500
Query: 450 M----GMRPPVMSQG 460
+PP G
Sbjct: 501 SQQPGSTKPPPQQPG 515
Score = 55.5 bits (132), Expect = 1e-07
Identities = 78/302 (25%), Positives = 94/302 (31%), Gaps = 52/302 (17%)
Query: 140 PPMAQPGLPPVPG-APGMPPGIPPLMPGVPPLMPGMPPVMPGMPPGLHHQRKYTQSFCGE 198
P + P PP+ PG PP PG PG P P P GL Q +
Sbjct: 296 PSLPSPSKPPIQQPTPGKPPA---QQPGHEKSQPG-PAKPPAQPSGLTKPLAQ-QPGTVK 350
Query: 199 NIMMPMGGMMPP----GPGIPPLM-----------PG-----MPPGM---PPPVPRPGIP 235
+ P G PP GP PP PG PPG+ P P P P
Sbjct: 351 PPVQPPGTTKPPAQPLGPAKPPAQQTGSEKPSSEQPGPKALAQPPGVGKTPAQQPGPAKP 410
Query: 236 PMTQAQAVSAPGILNRPPAPTATVPAPQPPVTKPLFPSAGQAQAAVQGPVGTD------F 289
P Q V P L + P + AP P T P G+ A GP T
Sbjct: 411 P---TQQVGTPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPT 467
Query: 290 KPLNSTPATTTEPPKPTFPA-----YTQSTASTTSTTNSTAAKPAASITSKPATLTTTSA 344
KP + P PP+ PA S + ST P +KP+ S
Sbjct: 468 KPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGST 527
Query: 345 TSKLIHPDEDISLEERRAQLPKYQRNLPRPGQAPIGNPPVGPIGGMMPPQPGIPQQQGMR 404
P + P Q+ P A PV G P QP +
Sbjct: 528 KPPSQQPG---------SAKPSAQQPSPAKPSAQQSTKPVSQTGSGKPLQPPTVSPSAKQ 578
Query: 405 PP 406
PP
Sbjct: 579 PP 580
Score = 53.5 bits (127), Expect = 4e-07
Identities = 60/198 (30%), Positives = 69/198 (34%), Gaps = 35/198 (17%)
Query: 128 QPQPVQP---QQGYIPPMAQ-PGLPPVPGAPGMPPGIPPLMPGVPPLMPGMPPVMPGMPP 183
QP P +P Q G P+AQ PGL APG P P PG PG P P
Sbjct: 404 QPGPAKPPTQQVGTPKPLAQQPGLQSPAKAPG-PTKTPVQQPG-----PGKIPAQQAGP- 456
Query: 184 GLHHQRKYTQSFCGENIMMPMGGMMPP----GPGIPPLMPGMPPGMPPPVPRPGIPPMTQ 239
G+ G PP GP PP P PP P PP Q
Sbjct: 457 -------------GKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQ 503
Query: 240 AQAVSAPGILNRPPAPTATVPAPQPP-VTKPLFPSAGQAQAAVQGPVGTDFKPLNST-PA 297
+ P P P P+PQ P TKP G A+ + Q P ST P
Sbjct: 504 PGSTKPP-----PQQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQSTKPV 558
Query: 298 TTTEPPKPTFPAYTQSTA 315
+ T KP P +A
Sbjct: 559 SQTGSGKPLQPPTVSPSA 576
Score = 48.5 bits (114), Expect = 1e-05
Identities = 57/243 (23%), Positives = 92/243 (37%), Gaps = 35/243 (14%)
Query: 122 AASTSFQPQPVQPQQGY----IPPMAQPGLPPVPGAPGMPPGIPPLMPGVPPLMPGMPPV 177
+ S S P +P+ + + AQP PP P P PP PP P +PP P +
Sbjct: 2378 SGSPSVSSLPAKPRPFFRSSSLDISAQPPPPPPPPPPPPPPPPPPPPPPLPPPTSPKPTI 2437
Query: 178 MPGMPPGLHHQRKYTQSFCGENIMMPMGGMMPPGPGIPPL-------MPGMPPGMPPPVP 230
+P ++K T + P+ P + L G+P
Sbjct: 2438 LP--------KKKLT-------VASPVTTATPLFDAVTTLETTAVLRSNGLPVTRICTTA 2482
Query: 231 RPGIPPMTQAQAVSAPGILNRPPAPTATVPAPQPPVTKPLFPSAGQAQAAVQ-GPVG--- 286
P +PP + ++ + + P P+ AP+P + P P+ Q + P G
Sbjct: 2483 PPPVPP--KPSSIPSGLVFTHRPEPSKPPIAPKPVI--PQLPTTTQKPTDIHPKPTGLSL 2538
Query: 287 TDFKPLNSTPATTTEPPKPTFPAYTQSTASTTSTTNS-TAAKPAASITSKPATLTTTSAT 345
T LN + + P PT P S S+ + S T ++ S+P T T +SA+
Sbjct: 2539 TSSMTLNLVTSADYKLPSPTSPLSPHSNKSSPRFSKSLTETYVVITLPSEPGTPTDSSAS 2598
Query: 346 SKL 348
+
Sbjct: 2599 QAI 2601
Score = 48.1 bits (113), Expect = 2e-05
Identities = 62/238 (26%), Positives = 84/238 (35%), Gaps = 32/238 (13%)
Query: 241 QAVSAPGILNRPPAPTATVPAPQPPVTKPLFP-------SAGQAQAAVQGPVGTDFKPLN 293
+ + P + +PP P +P Q P PL S+ Q + P GT KP+
Sbjct: 204 EGIIKPPLQQQPPKP---IPKQQGPGRDPLQQDGTPKSISSQQPEKIKSQPPGTG-KPIQ 259
Query: 294 STPATTTEPPKPTFPAYTQSTASTTSTTN---STAAKPAASITSKPATLTTTSATSKLIH 350
P T + P ++ T + + KP+ SKP T
Sbjct: 260 G-PTQTPQTDHAKLPLQRDASRPQTKQADIVRGESVKPSLPSPSKPPIQQPTPGKPPAQQ 318
Query: 351 PDEDISLEERRAQLPKYQRNLPRPGQAPIGN--PPVGPIGGMMPPQPGIPQQQGMRPPMP 408
P + S + A+ P L +P G PPV P G PP Q + P P
Sbjct: 319 PGHEKS-QPGPAKPPAQPSGLTKPLAQQPGTVKPPVQPPGTTKPPA------QPLGPAKP 371
Query: 409 PHGQYGGHHQG--MPGYLPGAMPPYGQGPPMVPPYQGGPPRPP---MGMRPPVMSQGG 461
P Q G PG A PP G P Q GP +PP +G P+ Q G
Sbjct: 372 PAQQTGSEKPSSEQPGPKALAQPP---GVGKTPAQQPGPAKPPTQQVGTPKPLAQQPG 426
Score = 45.4 bits (106), Expect = 1e-04
Identities = 54/218 (24%), Positives = 74/218 (33%), Gaps = 29/218 (13%)
Query: 128 QPQPVQPQQGYIPPMAQPGLPPVPGAPGMPPGIPPLMPGVPPLMPGMPPVMPGMPPGLHH 187
Q PVQ ++ P AQ + P P A MP G P PG P P P
Sbjct: 845 QVDPVQKKEE--PKKAQTKMSPKPDAKPMPKG-SPTPPGPRPTAGQTVPTPQQSPKPQEQ 901
Query: 188 QRKYTQSFCGENIMMPMGGMMPPGPGIPPLMPGM-------------PPGMPPPVPRPGI 234
R+++ + G P P + + G G P P + G
Sbjct: 902 SRRFSLNL-GSITDAPKSQPTTPQETVTGKLFGFGASIFSQASNLISTAGQPGPHSQSGP 960
Query: 235 -PPMTQAQAVSAP--------GILNRPPAPTATVPA---PQPPVTKPLFPSAGQAQAAVQ 282
PM QA A S P PPAP ++P + P + L P A QA +
Sbjct: 961 GAPMKQAPAPSQPPTSQGPPKSTGQAPPAPAKSIPVKKETKAPAAEKLEPKAEQAPTVKR 1020
Query: 283 GPVGTDFKPLNSTPATTTEPPKPTFPAYTQSTASTTST 320
P+ + + T EP K P + + ST
Sbjct: 1021 TETEKKPPPIKDSKSLTAEPQKAVLPTKLEKSPKPEST 1058
Score = 43.5 bits (101), Expect = 4e-04
Identities = 50/182 (27%), Positives = 67/182 (36%), Gaps = 32/182 (17%)
Query: 212 PGIPPLMPGMPPGMPPPVPRPGIPPMTQAQAVSAPGILNRPPAPTATVPAPQPPVTKPLF 271
P PP P PP PPP P P +PP T + P IL P TV +P T PLF
Sbjct: 2405 PPPPPPPPPPPPPPPPPPPPPPLPPPTSPK----PTIL---PKKKLTVASPVTTAT-PLF 2456
Query: 272 PSAGQAQAAV--------------QGPVGTDFKPLNSTPATTT-----EPPKPTF---PA 309
+ + P KP +S P+ EP KP P
Sbjct: 2457 DAVTTLETTAVLRSNGLPVTRICTTAPPPVPPKP-SSIPSGLVFTHRPEPSKPPIAPKPV 2515
Query: 310 YTQSTASTTSTTNSTAAKPAASITSKPATLTTTSATSKLIHPDEDISLEERRAQLPKYQR 369
Q +T T+ S+TS TSA KL P +S ++ P++ +
Sbjct: 2516 IPQLPTTTQKPTDIHPKPTGLSLTSSMTLNLVTSADYKLPSPTSPLSPHSNKSS-PRFSK 2574
Query: 370 NL 371
+L
Sbjct: 2575 SL 2576
Score = 41.6 bits (96), Expect = 0.002
Identities = 76/319 (23%), Positives = 105/319 (32%), Gaps = 101/319 (31%)
Query: 210 PGPGIPPLMPGMPPGMPPPVPRPGIPPMTQAQAVSAPGILNRPPAPTATVPAP------- 262
P P PP + P P + PP +A ++S P P P+ AP
Sbjct: 698 PEPKKPPPLVKQPTLHGSPSAKAKQPP--EADSLSKPAPPKEPSVPSEQDKAPVADDKPK 755
Query: 263 QPPVTKPLFPSAGQAQAAVQGPVGTDFKPLNSTPATTTEPPKPTFPAYTQSTASTTSTTN 322
QP + KP TD L S+ + TT+P P+ +Q+ TT
Sbjct: 756 QPKMVKPT----------------TD---LVSSSSATTKPDIPSSKVQSQAEEKTTPPLK 796
Query: 323 STAAKPAASITS--------KPATLTTTSATSKLI-HPDEDISLEERRAQLPKYQRNLPR 373
+ +AKP+ S + ++ SK+I HP + ++ P ++ P+
Sbjct: 797 TDSAKPSQSFPPTGEKVSPFDSKAIPRPASDSKIISHPGPSSESKGQKQVDPVQKKEEPK 856
Query: 374 PGQA-----------PIGNP-PVG--PIGGMMPPQP---GIPQQQGMR------------ 404
Q P G+P P G P G P P PQ+Q R
Sbjct: 857 KAQTKMSPKPDAKPMPKGSPTPPGPRPTAGQTVPTPQQSPKPQEQSRRFSLNLGSITDAP 916
Query: 405 --PPMPPH-------------------------GQYGGHHQGMPGYLPGAMPPYGQGP-P 436
P P GQ G H Q PG P Q P P
Sbjct: 917 KSQPTTPQETVTGKLFGFGASIFSQASNLISTAGQPGPHSQSGPG------APMKQAPAP 970
Query: 437 MVPPYQGGPPRPPMGMRPP 455
PP GPP+ G PP
Sbjct: 971 SQPPTSQGPPK-STGQAPP 988
Score = 33.5 bits (75), Expect = 0.42
Identities = 79/348 (22%), Positives = 108/348 (31%), Gaps = 82/348 (23%)
Query: 104 SQKKKQQDDSDEYDDDDSAASTSFQPQPVQPQQGYIPPMAQPGLPPVPGAPG-MPPGIPP 162
S+ Q + D S P+P +P P + QP L P A PP
Sbjct: 673 SKSSPQPQQTSPKKDAAPKQDLSKAPEPKKPP----PLVKQPTLHGSPSAKAKQPPEADS 728
Query: 163 LMPGVPPLMPGMP------PVMPGMPPGLHHQRKYT-------------------QSFCG 197
L PP P +P PV P + T QS
Sbjct: 729 LSKPAPPKEPSVPSEQDKAPVADDKPKQPKMVKPTTDLVSSSSATTKPDIPSSKVQSQAE 788
Query: 198 ENIMMPMG-GMMPPGPGIPPLMPGMPPGMPPPVPRPGIPPMTQAQAVSAPGILNRPPAPT 256
E P+ P PP + P +PRP + ++ +S PG P+
Sbjct: 789 EKTTPPLKTDSAKPSQSFPPTGEKVSPFDSKAIPRPA----SDSKIISHPG-----PSSE 839
Query: 257 ATVPAPQPPVTKPLFPSAGQAQAAVQGPVGTDFKPLNSTPATTTEPPKPTFPAYTQSTAS 316
+ PV K P Q + + + D KP+ P + PP P + TA
Sbjct: 840 SKGQKQVDPVQKKEEPKKAQTKMSPK----PDAKPM---PKGSPTPPGP------RPTAG 886
Query: 317 TTSTTNSTAAKPA----------ASITSKPATLTTTSATSKLIHPDEDIS--LEERRAQL 364
T T + KP SIT P + TT P E ++ L A +
Sbjct: 887 QTVPTPQQSPKPQEQSRRFSLNLGSITDAPKSQPTT--------PQETVTGKLFGFGASI 938
Query: 365 PKYQRNLPRPGQAPIGNPPVGPIGGMMPPQPGIPQQQGMRPPMPPHGQ 412
NL P + GP G P +Q P PP Q
Sbjct: 939 FSQASNLISTAGQPGPHSQSGP---------GAPMKQAPAPSQPPTSQ 977
Score = 32.0 bits (71), Expect = 1.2
Identities = 20/62 (32%), Positives = 37/62 (59%), Gaps = 5/62 (8%)
Query: 60 ETIDAVPNAIPGRTDIELEIYGMEG----IPEKDMDERRRLLEQKTQESQKKKQQDDSDE 115
ETID+VP + +++ E+ G E +PE+D +++ LE++ E +K KQQ ++E
Sbjct: 3176 ETIDSVPT-LTTASEVFPEVVGDESALLIVPEEDKQQQQLDLERELLELEKIKQQRFAEE 3234
Query: 116 YD 117
+
Sbjct: 3235 LE 3236
>gi|150378539 piccolo isoform 1 [Homo sapiens]
Length = 5142
Score = 80.1 bits (196), Expect = 4e-15
Identities = 100/375 (26%), Positives = 128/375 (34%), Gaps = 55/375 (14%)
Query: 99 QKTQESQKKKQQDDSDEYDDDDSAASTSFQPQPVQPQQGYIPPMAQPGLPPVPGAPGMPP 158
+ +QE KKQ+ E + Q QP +P IP PG P+ G P
Sbjct: 183 EASQEETTKKQKVVQKEQGKPEGIIKPPLQQQPPKP----IPKQQGPGRDPLQ-QDGTPK 237
Query: 159 GIPPLMPGVPPLMP---GMPPVMPGMPPGLHHQRKYTQSFCGENIMMPMGGMMPPGPGIP 215
I P P G P P P H + Q + G +
Sbjct: 238 SISSQQPEKIKSQPPGTGKPIQGPTQTPQTDHAKLPLQRDASRP--QTKQADIVRGESVK 295
Query: 216 PLMPGMPPGMPP-PVPRPGIPPMTQAQAVSAPGILNRPPAPTATVPAPQPPVTKPLFPSA 274
P +P P PP P PG PP Q PG P P A PA +TKPL
Sbjct: 296 PSLPS--PSKPPIQQPTPGKPPAQQ------PGHEKSQPGP-AKPPAQPSGLTKPLAQQP 346
Query: 275 GQAQAAVQGPVGTDFKPLNSTPATTTEPPKPTFPAYTQSTASTTSTTNSTAAKPAASITS 334
G + VQ P TT P +P PA + A T + ++ +P +
Sbjct: 347 GTVKPPVQ------------PPGTTKPPAQPLGPA--KPPAQQTGSEKPSSEQPGPKALA 392
Query: 335 KPATLTTTSATSK--LIHPDEDISLEERRAQLPKYQRNLPRPGQAPIGNPPVGPIGGMMP 392
+P + T A P + + + AQ P Q PG P P P G +P
Sbjct: 393 QPPGVGKTPAQQPGPAKPPTQQVGTPKPLAQQPGLQSPAKAPG--PTKTPVQQPGPGKIP 450
Query: 393 PQ---PGIPQQQGMRPPMPPHGQYGGHHQGMPGYLPGAMPPYGQGPPMVPPYQGGPPRPP 449
Q PG Q P PP +PG P PP GP PP Q G +PP
Sbjct: 451 AQQAGPGKTSAQQTGPTKPP--------SQLPG--PAKPPPQQPGPAKPPPQQPGSAKPP 500
Query: 450 M----GMRPPVMSQG 460
+PP G
Sbjct: 501 SQQPGSTKPPPQQPG 515
Score = 55.5 bits (132), Expect = 1e-07
Identities = 78/302 (25%), Positives = 94/302 (31%), Gaps = 52/302 (17%)
Query: 140 PPMAQPGLPPVPG-APGMPPGIPPLMPGVPPLMPGMPPVMPGMPPGLHHQRKYTQSFCGE 198
P + P PP+ PG PP PG PG P P P GL Q +
Sbjct: 296 PSLPSPSKPPIQQPTPGKPPA---QQPGHEKSQPG-PAKPPAQPSGLTKPLAQ-QPGTVK 350
Query: 199 NIMMPMGGMMPP----GPGIPPLM-----------PG-----MPPGM---PPPVPRPGIP 235
+ P G PP GP PP PG PPG+ P P P P
Sbjct: 351 PPVQPPGTTKPPAQPLGPAKPPAQQTGSEKPSSEQPGPKALAQPPGVGKTPAQQPGPAKP 410
Query: 236 PMTQAQAVSAPGILNRPPAPTATVPAPQPPVTKPLFPSAGQAQAAVQGPVGTD------F 289
P Q V P L + P + AP P T P G+ A GP T
Sbjct: 411 P---TQQVGTPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPT 467
Query: 290 KPLNSTPATTTEPPKPTFPA-----YTQSTASTTSTTNSTAAKPAASITSKPATLTTTSA 344
KP + P PP+ PA S + ST P +KP+ S
Sbjct: 468 KPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGST 527
Query: 345 TSKLIHPDEDISLEERRAQLPKYQRNLPRPGQAPIGNPPVGPIGGMMPPQPGIPQQQGMR 404
P + P Q+ P A PV G P QP +
Sbjct: 528 KPPSQQPG---------SAKPSAQQPSPAKPSAQQSTKPVSQTGSGKPLQPPTVSPSAKQ 578
Query: 405 PP 406
PP
Sbjct: 579 PP 580
Score = 53.5 bits (127), Expect = 4e-07
Identities = 60/198 (30%), Positives = 69/198 (34%), Gaps = 35/198 (17%)
Query: 128 QPQPVQP---QQGYIPPMAQ-PGLPPVPGAPGMPPGIPPLMPGVPPLMPGMPPVMPGMPP 183
QP P +P Q G P+AQ PGL APG P P PG PG P P
Sbjct: 404 QPGPAKPPTQQVGTPKPLAQQPGLQSPAKAPG-PTKTPVQQPG-----PGKIPAQQAGP- 456
Query: 184 GLHHQRKYTQSFCGENIMMPMGGMMPP----GPGIPPLMPGMPPGMPPPVPRPGIPPMTQ 239
G+ G PP GP PP P PP P PP Q
Sbjct: 457 -------------GKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQ 503
Query: 240 AQAVSAPGILNRPPAPTATVPAPQPP-VTKPLFPSAGQAQAAVQGPVGTDFKPLNST-PA 297
+ P P P P+PQ P TKP G A+ + Q P ST P
Sbjct: 504 PGSTKPP-----PQQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQSTKPV 558
Query: 298 TTTEPPKPTFPAYTQSTA 315
+ T KP P +A
Sbjct: 559 SQTGSGKPLQPPTVSPSA 576
Score = 48.5 bits (114), Expect = 1e-05
Identities = 57/243 (23%), Positives = 92/243 (37%), Gaps = 35/243 (14%)
Query: 122 AASTSFQPQPVQPQQGY----IPPMAQPGLPPVPGAPGMPPGIPPLMPGVPPLMPGMPPV 177
+ S S P +P+ + + AQP PP P P PP PP P +PP P +
Sbjct: 2378 SGSPSVSSLPAKPRPFFRSSSLDISAQPPPPPPPPPPPPPPPPPPPPPPLPPPTSPKPTI 2437
Query: 178 MPGMPPGLHHQRKYTQSFCGENIMMPMGGMMPPGPGIPPL-------MPGMPPGMPPPVP 230
+P ++K T + P+ P + L G+P
Sbjct: 2438 LP--------KKKLT-------VASPVTTATPLFDAVTTLETTAVLRSNGLPVTRICTTA 2482
Query: 231 RPGIPPMTQAQAVSAPGILNRPPAPTATVPAPQPPVTKPLFPSAGQAQAAVQ-GPVG--- 286
P +PP + ++ + + P P+ AP+P + P P+ Q + P G
Sbjct: 2483 PPPVPP--KPSSIPSGLVFTHRPEPSKPPIAPKPVI--PQLPTTTQKPTDIHPKPTGLSL 2538
Query: 287 TDFKPLNSTPATTTEPPKPTFPAYTQSTASTTSTTNS-TAAKPAASITSKPATLTTTSAT 345
T LN + + P PT P S S+ + S T ++ S+P T T +SA+
Sbjct: 2539 TSSMTLNLVTSADYKLPSPTSPLSPHSNKSSPRFSKSLTETYVVITLPSEPGTPTDSSAS 2598
Query: 346 SKL 348
+
Sbjct: 2599 QAI 2601
Score = 48.1 bits (113), Expect = 2e-05
Identities = 62/238 (26%), Positives = 84/238 (35%), Gaps = 32/238 (13%)
Query: 241 QAVSAPGILNRPPAPTATVPAPQPPVTKPLFP-------SAGQAQAAVQGPVGTDFKPLN 293
+ + P + +PP P +P Q P PL S+ Q + P GT KP+
Sbjct: 204 EGIIKPPLQQQPPKP---IPKQQGPGRDPLQQDGTPKSISSQQPEKIKSQPPGTG-KPIQ 259
Query: 294 STPATTTEPPKPTFPAYTQSTASTTSTTN---STAAKPAASITSKPATLTTTSATSKLIH 350
P T + P ++ T + + KP+ SKP T
Sbjct: 260 G-PTQTPQTDHAKLPLQRDASRPQTKQADIVRGESVKPSLPSPSKPPIQQPTPGKPPAQQ 318
Query: 351 PDEDISLEERRAQLPKYQRNLPRPGQAPIGN--PPVGPIGGMMPPQPGIPQQQGMRPPMP 408
P + S + A+ P L +P G PPV P G PP Q + P P
Sbjct: 319 PGHEKS-QPGPAKPPAQPSGLTKPLAQQPGTVKPPVQPPGTTKPPA------QPLGPAKP 371
Query: 409 PHGQYGGHHQG--MPGYLPGAMPPYGQGPPMVPPYQGGPPRPP---MGMRPPVMSQGG 461
P Q G PG A PP G P Q GP +PP +G P+ Q G
Sbjct: 372 PAQQTGSEKPSSEQPGPKALAQPP---GVGKTPAQQPGPAKPPTQQVGTPKPLAQQPG 426
Score = 45.4 bits (106), Expect = 1e-04
Identities = 54/218 (24%), Positives = 74/218 (33%), Gaps = 29/218 (13%)
Query: 128 QPQPVQPQQGYIPPMAQPGLPPVPGAPGMPPGIPPLMPGVPPLMPGMPPVMPGMPPGLHH 187
Q PVQ ++ P AQ + P P A MP G P PG P P P
Sbjct: 845 QVDPVQKKEE--PKKAQTKMSPKPDAKPMPKG-SPTPPGPRPTAGQTVPTPQQSPKPQEQ 901
Query: 188 QRKYTQSFCGENIMMPMGGMMPPGPGIPPLMPGM-------------PPGMPPPVPRPGI 234
R+++ + G P P + + G G P P + G
Sbjct: 902 SRRFSLNL-GSITDAPKSQPTTPQETVTGKLFGFGASIFSQASNLISTAGQPGPHSQSGP 960
Query: 235 -PPMTQAQAVSAP--------GILNRPPAPTATVPA---PQPPVTKPLFPSAGQAQAAVQ 282
PM QA A S P PPAP ++P + P + L P A QA +
Sbjct: 961 GAPMKQAPAPSQPPTSQGPPKSTGQAPPAPAKSIPVKKETKAPAAEKLEPKAEQAPTVKR 1020
Query: 283 GPVGTDFKPLNSTPATTTEPPKPTFPAYTQSTASTTST 320
P+ + + T EP K P + + ST
Sbjct: 1021 TETEKKPPPIKDSKSLTAEPQKAVLPTKLEKSPKPEST 1058
Score = 43.5 bits (101), Expect = 4e-04
Identities = 50/182 (27%), Positives = 67/182 (36%), Gaps = 32/182 (17%)
Query: 212 PGIPPLMPGMPPGMPPPVPRPGIPPMTQAQAVSAPGILNRPPAPTATVPAPQPPVTKPLF 271
P PP P PP PPP P P +PP T + P IL P TV +P T PLF
Sbjct: 2405 PPPPPPPPPPPPPPPPPPPPPPLPPPTSPK----PTIL---PKKKLTVASPVTTAT-PLF 2456
Query: 272 PSAGQAQAAV--------------QGPVGTDFKPLNSTPATTT-----EPPKPTF---PA 309
+ + P KP +S P+ EP KP P
Sbjct: 2457 DAVTTLETTAVLRSNGLPVTRICTTAPPPVPPKP-SSIPSGLVFTHRPEPSKPPIAPKPV 2515
Query: 310 YTQSTASTTSTTNSTAAKPAASITSKPATLTTTSATSKLIHPDEDISLEERRAQLPKYQR 369
Q +T T+ S+TS TSA KL P +S ++ P++ +
Sbjct: 2516 IPQLPTTTQKPTDIHPKPTGLSLTSSMTLNLVTSADYKLPSPTSPLSPHSNKSS-PRFSK 2574
Query: 370 NL 371
+L
Sbjct: 2575 SL 2576
Score = 41.6 bits (96), Expect = 0.002
Identities = 76/319 (23%), Positives = 105/319 (32%), Gaps = 101/319 (31%)
Query: 210 PGPGIPPLMPGMPPGMPPPVPRPGIPPMTQAQAVSAPGILNRPPAPTATVPAP------- 262
P P PP + P P + PP +A ++S P P P+ AP
Sbjct: 698 PEPKKPPPLVKQPTLHGSPSAKAKQPP--EADSLSKPAPPKEPSVPSEQDKAPVADDKPK 755
Query: 263 QPPVTKPLFPSAGQAQAAVQGPVGTDFKPLNSTPATTTEPPKPTFPAYTQSTASTTSTTN 322
QP + KP TD L S+ + TT+P P+ +Q+ TT
Sbjct: 756 QPKMVKPT----------------TD---LVSSSSATTKPDIPSSKVQSQAEEKTTPPLK 796
Query: 323 STAAKPAASITS--------KPATLTTTSATSKLI-HPDEDISLEERRAQLPKYQRNLPR 373
+ +AKP+ S + ++ SK+I HP + ++ P ++ P+
Sbjct: 797 TDSAKPSQSFPPTGEKVSPFDSKAIPRPASDSKIISHPGPSSESKGQKQVDPVQKKEEPK 856
Query: 374 PGQA-----------PIGNP-PVG--PIGGMMPPQP---GIPQQQGMR------------ 404
Q P G+P P G P G P P PQ+Q R
Sbjct: 857 KAQTKMSPKPDAKPMPKGSPTPPGPRPTAGQTVPTPQQSPKPQEQSRRFSLNLGSITDAP 916
Query: 405 --PPMPPH-------------------------GQYGGHHQGMPGYLPGAMPPYGQGP-P 436
P P GQ G H Q PG P Q P P
Sbjct: 917 KSQPTTPQETVTGKLFGFGASIFSQASNLISTAGQPGPHSQSGPG------APMKQAPAP 970
Query: 437 MVPPYQGGPPRPPMGMRPP 455
PP GPP+ G PP
Sbjct: 971 SQPPTSQGPPK-STGQAPP 988
Score = 33.5 bits (75), Expect = 0.42
Identities = 79/348 (22%), Positives = 108/348 (31%), Gaps = 82/348 (23%)
Query: 104 SQKKKQQDDSDEYDDDDSAASTSFQPQPVQPQQGYIPPMAQPGLPPVPGAPG-MPPGIPP 162
S+ Q + D S P+P +P P + QP L P A PP
Sbjct: 673 SKSSPQPQQTSPKKDAAPKQDLSKAPEPKKPP----PLVKQPTLHGSPSAKAKQPPEADS 728
Query: 163 LMPGVPPLMPGMP------PVMPGMPPGLHHQRKYT-------------------QSFCG 197
L PP P +P PV P + T QS
Sbjct: 729 LSKPAPPKEPSVPSEQDKAPVADDKPKQPKMVKPTTDLVSSSSATTKPDIPSSKVQSQAE 788
Query: 198 ENIMMPMG-GMMPPGPGIPPLMPGMPPGMPPPVPRPGIPPMTQAQAVSAPGILNRPPAPT 256
E P+ P PP + P +PRP + ++ +S PG P+
Sbjct: 789 EKTTPPLKTDSAKPSQSFPPTGEKVSPFDSKAIPRPA----SDSKIISHPG-----PSSE 839
Query: 257 ATVPAPQPPVTKPLFPSAGQAQAAVQGPVGTDFKPLNSTPATTTEPPKPTFPAYTQSTAS 316
+ PV K P Q + + + D KP+ P + PP P + TA
Sbjct: 840 SKGQKQVDPVQKKEEPKKAQTKMSPK----PDAKPM---PKGSPTPPGP------RPTAG 886
Query: 317 TTSTTNSTAAKPA----------ASITSKPATLTTTSATSKLIHPDEDIS--LEERRAQL 364
T T + KP SIT P + TT P E ++ L A +
Sbjct: 887 QTVPTPQQSPKPQEQSRRFSLNLGSITDAPKSQPTT--------PQETVTGKLFGFGASI 938
Query: 365 PKYQRNLPRPGQAPIGNPPVGPIGGMMPPQPGIPQQQGMRPPMPPHGQ 412
NL P + GP G P +Q P PP Q
Sbjct: 939 FSQASNLISTAGQPGPHSQSGP---------GAPMKQAPAPSQPPTSQ 977
Score = 32.0 bits (71), Expect = 1.2
Identities = 20/62 (32%), Positives = 37/62 (59%), Gaps = 5/62 (8%)
Query: 60 ETIDAVPNAIPGRTDIELEIYGMEG----IPEKDMDERRRLLEQKTQESQKKKQQDDSDE 115
ETID+VP + +++ E+ G E +PE+D +++ LE++ E +K KQQ ++E
Sbjct: 3176 ETIDSVPT-LTTASEVFPEVVGDESALLIVPEEDKQQQQLDLERELLELEKIKQQRFAEE 3234
Query: 116 YD 117
+
Sbjct: 3235 LE 3236
>gi|146134388 YLP motif containing 1 [Homo sapiens]
Length = 2146
Score = 78.6 bits (192), Expect = 1e-14
Identities = 102/363 (28%), Positives = 141/363 (38%), Gaps = 70/363 (19%)
Query: 129 PQPVQPQQGYIPP---MAQPGLPPVPGAPGMPPGIPPLM--PGVPPLMPGMPPVM----- 178
P P P PP M P LPP P MPP +P + PG+PP P MPP +
Sbjct: 517 PPPFVPYSQMPPPLPTMPPPVLPPSLPPPVMPPALPATVPPPGMPP--PVMPPSLPTSVP 574
Query: 179 -PGMPPGLHHQRKYTQSFCGENIMMPMGGMMPPGPGIPPLMPGMPPGM----PPPV-PRP 232
PGMPP L S G ++P + GP PP++P PP + PPPV P P
Sbjct: 575 PPGMPPSL--------SSAGPPPVLPPPSLSSAGP--PPVLP--PPSLSSTAPPPVMPLP 622
Query: 233 GIPPMTQAQAVSAPGI-LNRPPAPTATVPAPQPPVTKPLFPSAGQAQAAVQGPVGTDFKP 291
+ T + PG+ PP TA AP PP + + P F
Sbjct: 623 PLSSATPPPGIPPPGVPQGIPPQLTA---APVPPASSSQSSQVPEKPRPALLPTPVSF-- 677
Query: 292 LNSTPATTTEPPKPTFPAYTQSTASTTSTTNSTAAKPAASITSKPATLTTTSATSKLIHP 351
S P TT PP + S + S +A P +S +S +++A S+ I
Sbjct: 678 -GSAPPTTYHPP---LQSAGPSEQVNSKAPLSKSALPYSSFSSDQGLGESSAAPSQPITA 733
Query: 352 DEDISLEERRAQLPKYQRNLPRPGQAPIGNPPVGP----------IGGMMP-PQPGIPQQ 400
+D+ + LP P ++ P GP +G P+P P+
Sbjct: 734 VKDMPVRSGGL--------LPDPPRSSYLESPRGPRFDGPRRFEDLGSRCEGPRPKGPRF 785
Query: 401 QGMRPPMPPHGQYGGH----HQGMPGYLP--GAMPPYGQGPPMVPPYQGGP----PRPPM 450
+G RP P +Y GH + G +P A Y + P Q GP P+P
Sbjct: 786 EGNRPD-GPRPRYEGHPAEGTKSKWGMIPRGPASQFYITPSTSLSPRQSGPQWKGPKPAF 844
Query: 451 GMR 453
G +
Sbjct: 845 GQQ 847
Score = 65.1 bits (157), Expect = 1e-10
Identities = 89/376 (23%), Positives = 137/376 (36%), Gaps = 110/376 (29%)
Query: 124 STSFQPQPVQPQQGYIPPMAQPG-------LPPVPGAPG--------------------- 155
S+ + P PV P P A PG P P + G
Sbjct: 11 SSHYPPPPVPPPPPVALPEASPGPGYSSSTTPAAPSSSGFMSFREQHLAQLQQLQQMHQK 70
Query: 156 ----------MPPGIPPLMPGVPPLMPG--------MPPVMPGMPPG------------- 184
+PP PPL P PP+MPG PP MP PPG
Sbjct: 71 QMQCVLQPHHLPP--PPLPP--PPVMPGGGYGDWQPPPPPMP-PPPGPALSYQKQQQYKH 125
Query: 185 --LHHQRKYTQSFCGENIMMPMGGMMPPGPGIPPLMPG--MPPG---MPPPVPRPGIPPM 237
LHHQR G ++PM PP PP+ PG MPP MPPP P P P
Sbjct: 126 QMLHHQRD------GPPGLVPMELESPPES--PPVPPGSYMPPSQSYMPPPQPPPSYYPP 177
Query: 238 TQAQAVSAPGILNRPPAPTATVPAPQPPVTKPLFPSAGQAQAAVQGPVGTDFKPLNSTPA 297
T +Q P P+P+ + P+ P + S+ + + + ++P+
Sbjct: 178 TSSQPYLPPA----QPSPSQSPPSQSYLAPTPSYSSSSSSSQSYLSHSQSYLPSSQASPS 233
Query: 298 TTTE---------PPKPTFPAYTQSTAS----TTSTTNSTAAKPAASITSKPATLTTTSA 344
++ PP P+ P ++T + N + + A+ P+T+ T
Sbjct: 234 RPSQGHSKSQLLAPPPPSAPPGNKTTVQQEPLESGAKNKSTEQQQAAPEPDPSTM-TPQE 292
Query: 345 TSKLIHPDEDISLEER-RAQLPKYQ------RNLPRPGQAPIGNPPVGPI----GGMMPP 393
+ + +SL++R + LP ++ ++ P P + + P + PP
Sbjct: 293 QQQYWYRQHLLSLQQRTKVHLPGHKKGPVVAKDTPEPVKEEVTVPATSQVPESPSSEEPP 352
Query: 394 QPGIPQQQGMRPPMPP 409
P P + + PP+PP
Sbjct: 353 LP--PPNEEVPPPLPP 366
Score = 61.2 bits (147), Expect = 2e-09
Identities = 103/462 (22%), Positives = 164/462 (35%), Gaps = 77/462 (16%)
Query: 21 DDEKILIQHQKAKHFKCHICHKKLYTGPGLAI------HCMQVHKETIDAVPNAIPGRTD 74
+D ++ A H++ H H+ + G+ +Q +++ I P+ D
Sbjct: 376 EDARLKQLQAAAAHWQQHQQHRVGFQYQGIMQKHTQLQQILQQYQQIIQPPPHIQTMSVD 435
Query: 75 IELEIYGMEGIPEKDM-DERRRLLEQKTQESQKKKQQDDSDEYDDD------DSAASTSF 127
++L Y M+ + + E R + ++ +D EY+ A+ S+
Sbjct: 436 MQLRHYEMQQQQFQHLYQEWEREFQLWEEQLHSYPHKDQLQEYEKQWKTWQGHMKATQSY 495
Query: 128 QPQPVQPQQG----YIPPMAQPGLPPVPGAPGMPPGIPPLMPGVPPLMPGMPPVMPGMPP 183
+ V Q Y+ M+ P PP MPP +P + P P L P +PP P MPP
Sbjct: 496 LQEKVNSFQNMKNQYMGNMSMP--PPFVPYSQMPPPLPTMPP--PVLPPSLPP--PVMPP 549
Query: 184 GLHHQRKYTQSFCGENIMMPMGGMMPPGPGIPPLMPGMPPGMPPP-----VPRPGIPPMT 238
L +PP PGMPP + PP VP PG+PP
Sbjct: 550 ALPAT-------------------------VPP--PGMPPPVMPPSLPTSVPPPGMPP-- 580
Query: 239 QAQAVSAPGILNRPPAPTATVPAPQPPVTKPLFPSAGQAQAAVQGPVGTDFKPLNSTPAT 298
+ P +L P P+ + P P + P S P+ + P P
Sbjct: 581 SLSSAGPPPVL---PPPSLSSAGPPPVLPPPSLSSTAPPPVMPLPPLSSATPPPGIPPPG 637
Query: 299 TTEPPKPTFPAYTQSTASTTSTTNSTAAKPAASITSKPATL-----TTTSATSKLIHPDE 353
+ P A AS +S ++ KP ++ P + TT + P E
Sbjct: 638 VPQGIPPQLTAAPVPPAS-SSQSSQVPEKPRPALLPTPVSFGSAPPTTYHPPLQSAGPSE 696
Query: 354 DISLEE--RRAQLPKYQRNLPRPGQAPIGNPPVGPIGGMMPPQPGIPQQQGMRPPMPPHG 411
++ + ++ LP Y G P PI + +P + G P PP
Sbjct: 697 QVNSKAPLSKSALP-YSSFSSDQGLGESSAAPSQPITAV----KDMPVRSGGLLPDPPRS 751
Query: 412 QYGGHHQGMPGYLPGAMPPYG---QGP-PMVPPYQGGPPRPP 449
Y +G P G +GP P P ++G P P
Sbjct: 752 SYLESPRGPRFDGPRRFEDLGSRCEGPRPKGPRFEGNRPDGP 793
Score = 51.2 bits (121), Expect = 2e-06
Identities = 52/186 (27%), Positives = 70/186 (37%), Gaps = 37/186 (19%)
Query: 88 KDMDERRRLLEQKTQESQKKKQQDDSDEYD----DDDSAASTSFQPQPVQPQQGYIPPMA 143
K E + L EQK Q + K + D + +TS +P P Y PP
Sbjct: 1458 KAAQELKMLREQKEQLQKMKDFGSEPQMADHLPPQESRLQNTSSRPGMYPPPGSYRPPPP 1517
Query: 144 Q---PGLPPVPGAPGMPPGIPPLMPGVPPLMPGMPPVMPGMPP-------GLHHQRKYTQ 193
PG P AP +P P VP P PP +P PP + +R
Sbjct: 1518 MGKPPGSIVRPSAPPARSSVPVTRPPVPIPPPPPPPPLPPPPPVIKPQTSAVEQERWDED 1577
Query: 194 SFCG----------------ENIMMPMGGMMPPGPGIPPLMPGMPPGMPPPVPRPGIPPM 237
SF G E +P ++PP PP+ +PP P PVP G+PPM
Sbjct: 1578 SFYGLWDTNDEQGLNSEFKSETAAIPSAPVLPP----PPVHSSIPP--PGPVPM-GMPPM 1630
Query: 238 TQAQAV 243
++ V
Sbjct: 1631 SKPPPV 1636
Score = 45.8 bits (107), Expect = 8e-05
Identities = 50/183 (27%), Positives = 67/183 (36%), Gaps = 36/183 (19%)
Query: 296 PATTTEPPKPTFPAYTQSTASTTSTTNSTAAKPAASITSKPATLTTTSATSKLIHPDEDI 355
P PP P + ++STT PAA +S + L +
Sbjct: 16 PPPVPPPPPVALPEASPGPGYSSSTT------PAAPSSSGFMSFRE----QHLAQLQQLQ 65
Query: 356 SLEERRAQLPKYQRNLPRPGQAPIGNPPVGPIGGM---MPPQPGIPQQQGMRPPMPPHGQ 412
+ +++ Q +LP P P+ PPV P GG PP P +P G Q
Sbjct: 66 QMHQKQMQCVLQPHHLPPP---PLPPPPVMPGGGYGDWQPPPPPMPPPPGPALSYQKQQQ 122
Query: 413 YGG---HHQ--GMPGYLPGAMPPYGQGPPMVPPYQGG-----------PPRPPMGMRPPV 456
Y HHQ G PG +P + + PP PP G PP+PP PP
Sbjct: 123 YKHQMLHHQRDGPPGLVPMEL----ESPPESPPVPPGSYMPPSQSYMPPPQPPPSYYPPT 178
Query: 457 MSQ 459
SQ
Sbjct: 179 SSQ 181
Score = 45.1 bits (105), Expect = 1e-04
Identities = 27/72 (37%), Positives = 33/72 (45%), Gaps = 4/72 (5%)
Query: 198 ENIMMPMGGMMPPGPGIPPLMPGMPPGMPPPVPRPGIPPMTQAQAVSAPGILNRPPAPTA 257
+N G PPG PP G PPG + RP PP + V+ P + PP P
Sbjct: 1497 QNTSSRPGMYPPPGSYRPPPPMGKPPGS---IVRPSAPPARSSVPVTRPPVPIPPPPPPP 1553
Query: 258 TVPAPQPPVTKP 269
+P P PPV KP
Sbjct: 1554 PLP-PPPPVIKP 1564
Score = 40.4 bits (93), Expect = 0.003
Identities = 52/213 (24%), Positives = 71/213 (33%), Gaps = 34/213 (15%)
Query: 226 PPPVPRPGIPPMTQAQAVSAPGILNRPPAPTATVPAPQPPVTKPLFPSAGQAQAAVQGPV 285
PPPVP P PP+ +A PG + P A + + Q Q Q +
Sbjct: 16 PPPVPPP--PPVALPEASPGPGY-SSSTTPAAPSSSGFMSFREQHLAQLQQLQQMHQKQM 72
Query: 286 GTDFKPLNSTPATTTEPPKPTFPAYTQSTASTTSTTNSTAAKPAASITSKPATLTTTSAT 345
+P + P PP P P PA S +
Sbjct: 73 QCVLQPHHLPPPPL--PPPPVMPGGGYGDWQPPPPPMPPPPGPALSYQKQ---------- 120
Query: 346 SKLIHPDEDISLEERRAQLPKYQRNLPRPGQAP--IGNPPVGPIGGMMPPQPGIPQQQGM 403
++ + Q+ +QR+ P PG P + +PP P +PP +P Q
Sbjct: 121 ------------QQYKHQMLHHQRDGP-PGLVPMELESPPESP---PVPPGSYMPPSQSY 164
Query: 404 RPPMPPHGQYGGHHQGMPGYLPGAMPPYGQGPP 436
PP P Y P YLP A P Q PP
Sbjct: 165 MPPPQPPPSYYPPTSSQP-YLPPAQPSPSQSPP 196
Score = 40.4 bits (93), Expect = 0.003
Identities = 40/121 (33%), Positives = 43/121 (35%), Gaps = 24/121 (19%)
Query: 364 LPKYQRNLPRPGQAPIGNPPVGPIGGMMPPQPGIPQQQGMRPP-MPPHGQYGGHHQGMPG 422
+P Q P P P PP P M P P GM PP MPP GMP
Sbjct: 521 VPYSQMPPPLPTMPPPVLPPSLPPPVMPPALPATVPPPGMPPPVMPPSLPTSVPPPGMPP 580
Query: 423 YLPGAMPP--------YGQGPPMV-----------PPYQGGPP----RPPMGMRPPVMSQ 459
L A PP GPP V PP PP PP G+ PP + Q
Sbjct: 581 SLSSAGPPPVLPPPSLSSAGPPPVLPPPSLSSTAPPPVMPLPPLSSATPPPGIPPPGVPQ 640
Query: 460 G 460
G
Sbjct: 641 G 641
Score = 38.1 bits (87), Expect = 0.017
Identities = 55/252 (21%), Positives = 78/252 (30%), Gaps = 24/252 (9%)
Query: 124 STSFQPQPVQPQQGYIPPMAQPGLPPVPGAPGM-PPGIPPLMPGVPPLMPGMPPVMPGMP 182
S S+ P P P Y P +QP LPP +P PP L P P
Sbjct: 161 SQSYMPPPQPPPSYYPPTSSQPYLPPAQPSPSQSPPSQSYLAP-----TPSYSSSSSSSQ 215
Query: 183 PGLHHQRKYTQSFCGENIMMPMGGMMPPGPGIPPLMPGMPPGMPPPVPRPGIPPMTQAQA 242
L H + Y S P G P PPP PG Q +
Sbjct: 216 SYLSHSQSYLPS--------SQASPSRPSQGHSKSQLLAP---PPPSAPPGNKTTVQQEP 264
Query: 243 VSAPGILNRPPAPTATVPAPQPPVTKPLFPSA---GQAQAAVQGPVGTDFKPLNSTPATT 299
+ + G N+ P P P P Q ++Q P
Sbjct: 265 LES-GAKNKSTEQQQAAPEPDPSTMTPQEQQQYWYRQHLLSLQQRTKVHLPGHKKGPVVA 323
Query: 300 TEPPKPTFPAYTQSTASTTSTTNSTAAKPAASITSK-PATLTTTSATSKLIHPDEDISLE 358
+ P+P T S + S+ P + P L S+ P+ED L+
Sbjct: 324 KDTPEPVKEEVTVPATSQVPESPSSEEPPLPPPNEEVPPPLPPEEPQSE--DPEEDARLK 381
Query: 359 ERRAQLPKYQRN 370
+ +A +Q++
Sbjct: 382 QLQAAAAHWQQH 393
Score = 33.5 bits (75), Expect = 0.42
Identities = 52/258 (20%), Positives = 71/258 (27%), Gaps = 57/258 (22%)
Query: 215 PPLMPGMPPGMPPPVPRPGIPPMTQAQAVSAPGILNRPPAPTATV--------------- 259
PP+ P P +P P PG T A S+ G ++ A +
Sbjct: 17 PPVPPPPPVALPEASPGPGYSSSTTPAAPSSSGFMSFREQHLAQLQQLQQMHQKQMQCVL 76
Query: 260 ------PAPQPPVTKPLFPSAGQAQAAVQGPVGTDFKPLNSTPATTTEPPKPTFPAYTQS 313
P P PP P+ P G D++P P PP P Q
Sbjct: 77 QPHHLPPPPLPP--PPVMPGGGYG----------DWQP---PPPPMPPPPGPALSYQKQQ 121
Query: 314 TASTTSTTNSTAAKPAASITSKPATLTTTSATSKLIHPDEDISLEERRAQLPKYQRNLPR 373
+ P +L P E + + +P Q +P
Sbjct: 122 QYKHQMLHHQRDGPPGL-------------VPMELESPPESPPVPPG-SYMPPSQSYMPP 167
Query: 374 PGQAPIGNPPVGPIGGMMPPQPGIPQQQGMRPPMPPHGQYGGHHQGMPGYLPGAMPPYGQ 433
P P PP + P QP Q + + P Y YL
Sbjct: 168 PQPPPSYYPPTSSQPYLPPAQPSPSQSPPSQSYLAPTPSYSSSSSSSQSYL-------SH 220
Query: 434 GPPMVPPYQGGPPRPPMG 451
+P Q P RP G
Sbjct: 221 SQSYLPSSQASPSRPSQG 238
Score = 33.5 bits (75), Expect = 0.42
Identities = 30/96 (31%), Positives = 36/96 (37%), Gaps = 26/96 (27%)
Query: 363 QLPKYQRNLPRPGQAPIGNPPVGPIGGMMPPQP-GIPQQQGMRPPMPPHGQYGGHHQGMP 421
Q + Q RPG P P G PP P G P +RP PP
Sbjct: 1492 QESRLQNTSSRPGMYP-------PPGSYRPPPPMGKPPGSIVRPSAPP----------AR 1534
Query: 422 GYLPGAMPPYGQGPPMVPPYQGGPPRPPMGMRPPVM 457
+P PP P+ PP PP PP+ PPV+
Sbjct: 1535 SSVPVTRPPV----PIPPP----PPPPPLPPPPPVI 1562
Score = 32.3 bits (72), Expect = 0.93
Identities = 25/70 (35%), Positives = 28/70 (40%), Gaps = 5/70 (7%)
Query: 391 MPPQPGIPQQQGMRPPM-PPHGQYGGHHQ--GMPGYL--PGAMPPYGQGPPMVPPYQGGP 445
+PPQ Q RP M PP G Y PG + P A P P PP P
Sbjct: 1489 LPPQESRLQNTSSRPGMYPPPGSYRPPPPMGKPPGSIVRPSAPPARSSVPVTRPPVPIPP 1548
Query: 446 PRPPMGMRPP 455
P PP + PP
Sbjct: 1549 PPPPPPLPPP 1558
>gi|224451133 splicing factor, arginine/serine-rich 15 isoform 2
[Homo sapiens]
Length = 1132
Score = 78.2 bits (191), Expect = 1e-14
Identities = 100/351 (28%), Positives = 126/351 (35%), Gaps = 91/351 (25%)
Query: 120 DSAASTSFQPQPVQPQQGYIPPMAQPGLPPVPGAPGMPPGIPPLMPGVPPLMPGMPPVMP 179
+ A TS +PV P IP +PP+P P P +PP P VPP PG P V
Sbjct: 629 NGGAETS-HTEPVSP----IPKPLPVPVPPIP-VPA-PITVPP--PQVPPHQPGPPVVGA 679
Query: 180 GMPPGLHHQRKYTQSFCGENIMMPMGGMMPPG--PGIPPLMPGMPPGMPPPVPRPGIPPM 237
PP P G+ PPG PG+PP P PPP RPG PM
Sbjct: 680 LQPPAF----------------TPPLGIPPPGFGPGVPP------PPPPPPFLRPGFNPM 717
Query: 238 TQAQAVSAPGILNRPPAPTATVPAPQPPVTKPLFPSAGQAQAAVQGPVGTDFKPLNSTPA 297
PG L P P T P PP P A + D N
Sbjct: 718 HLP-----PGFLPPGPPPPITPPVSIPPPHTPPISIPNSTIAGINEDTTKDLSIGN---- 768
Query: 298 TTTEPPKPTFPAYTQSTASTTSTTN--STAAKPAA--SITSKPATLTTTSATSKLIHPDE 353
P PT + + A + + +A PAA ++ + P T + ++ + P
Sbjct: 769 -----PIPTVVSGARGNAESGDSVKMYGSAVPPAAPTNLPTPPVTQPVSLLGTQGVAPGP 823
Query: 354 DISLEERRAQLPKYQRNLPRPGQAPIGNPPVGPIGGMMPPQ----PGIPQQQGMRPPMPP 409
I L Q P RPG P+ PP GM PP P +P + PMPP
Sbjct: 824 VIGL-----QAPSTGLLGARPGLIPLQRPP-----GMPPPHLQRFPLMPPR-----PMPP 868
Query: 410 HGQYGGHHQGMPGYLPGAMPPYGQGPPMVPPYQGGPPRPPMGMRPPVMSQG 460
H + G PP G G +PP P GM+ P G
Sbjct: 869 HMMHRG-------------PPPGPGGFAMPP--------PHGMKGPFPPHG 898
Score = 50.4 bits (119), Expect = 3e-06
Identities = 46/131 (35%), Positives = 54/131 (41%), Gaps = 15/131 (11%)
Query: 143 AQPGLPPVPGAPGMPPG------IPPLMPGVPPLMPGMPPVMPG---MPP--GLHHQRKY 191
A+PGL P+ PGMPP + P P P +M PP PG MPP G+
Sbjct: 837 ARPGLIPLQRPPGMPPPHLQRFPLMPPRPMPPHMMHRGPPPGPGGFAMPPPHGMKGPFPP 896
Query: 192 TQSFCGENIMMPMGGMMPPGPGIPPLMPG--MPPGMPPPVPRPGIPPMTQAQAVSAPGIL 249
F M +GG PGPG P G PP P P+P P Q Q P
Sbjct: 897 HGPFVRPGGMPGLGGP-GPGPGGPEDRDGRQQPPQQPQQQPQPQAPQQPQQQQQQQPPPS 955
Query: 250 NRPPAPTATVP 260
+PP PT P
Sbjct: 956 QQPP-PTQQQP 965
Score = 38.1 bits (87), Expect = 0.017
Identities = 57/242 (23%), Positives = 75/242 (30%), Gaps = 61/242 (25%)
Query: 224 GMPPPVPRPGIPPMTQAQAVSAPGILNRPPAPTATVPAPQPPVTK-------------PL 270
G PPP + P TQA S P + P + A T+ P
Sbjct: 138 GSPPPPVKVSSEPPTQATPNSVPAVPQLPSSDAFAAVAQLFQTTQGQQLQQILQTFQQPP 197
Query: 271 FPSAGQAQAAVQGPVGTDFKPLNSTPATTTEPPKPTFPAYTQSTA--------------- 315
P + AV V L +TP +E K FP Q TA
Sbjct: 198 KPQSPALDNAVMAQVQAITAQLKTTPTQPSEQ-KAAFPPPEQKTAFDKKLLDRFDYDDEP 256
Query: 316 -----------STTSTTNSTAAKPAASITSKPATLTTTSATSKLIHPDEDISLEERRAQL 364
+ +TT AA P A + PA +A+ P Q
Sbjct: 257 EAVEESKKEDTTAVTTTAPAAAVPPAPTATVPAAAAPAAASPP--PPQAPFGFPGDGMQQ 314
Query: 365 PKYQRNL---------------PRPGQAPIGNPPVG--PIGGMMPPQPGIPQQQGMRPPM 407
P Y ++ P Q P+ PP G P G++P P P Q + PP
Sbjct: 315 PAYTQHQNMDQFQPRMMGIQQDPMHHQVPL--PPNGQMPGFGLLPTPPFPPMAQPVIPPT 372
Query: 408 PP 409
PP
Sbjct: 373 PP 374
Score = 38.1 bits (87), Expect = 0.017
Identities = 44/149 (29%), Positives = 58/149 (38%), Gaps = 21/149 (14%)
Query: 98 EQKTQESQKKKQQDDSDEYDD-------DDSAASTSFQPQPVQPQQ--GYIPPMAQPGL- 147
EQKT +K + D D+ + +D+ A T+ P P +P A P
Sbjct: 237 EQKTAFDKKLLDRFDYDDEPEAVEESKKEDTTAVTTTAPAAAVPPAPTATVPAAAAPAAA 296
Query: 148 -PPVPGAPGMPPGIPPLMPGVPPL--MPGMPPVMPGMPPG-LHHQRKYTQSFCGENIMMP 203
PP P AP PG P M P M G+ +HHQ N MP
Sbjct: 297 SPPPPQAPFGFPGDGMQQPAYTQHQNMDQFQPRMMGIQQDPMHHQVPLPP-----NGQMP 351
Query: 204 MGGMMPPGPGIPPLMPGMPPGMPPPVPRP 232
G++P P P P +PP PPV +P
Sbjct: 352 GFGLLPTPPFPPMAQPVIPP--TPPVQQP 378
>gi|40789229 splicing factor, arginine/serine-rich 15 isoform 1
[Homo sapiens]
Length = 1147
Score = 78.2 bits (191), Expect = 1e-14
Identities = 100/351 (28%), Positives = 126/351 (35%), Gaps = 91/351 (25%)
Query: 120 DSAASTSFQPQPVQPQQGYIPPMAQPGLPPVPGAPGMPPGIPPLMPGVPPLMPGMPPVMP 179
+ A TS +PV P IP +PP+P P P +PP P VPP PG P V
Sbjct: 644 NGGAETS-HTEPVSP----IPKPLPVPVPPIP-VPA-PITVPP--PQVPPHQPGPPVVGA 694
Query: 180 GMPPGLHHQRKYTQSFCGENIMMPMGGMMPPG--PGIPPLMPGMPPGMPPPVPRPGIPPM 237
PP P G+ PPG PG+PP P PPP RPG PM
Sbjct: 695 LQPPAF----------------TPPLGIPPPGFGPGVPP------PPPPPPFLRPGFNPM 732
Query: 238 TQAQAVSAPGILNRPPAPTATVPAPQPPVTKPLFPSAGQAQAAVQGPVGTDFKPLNSTPA 297
PG L P P T P PP P A + D N
Sbjct: 733 HLP-----PGFLPPGPPPPITPPVSIPPPHTPPISIPNSTIAGINEDTTKDLSIGN---- 783
Query: 298 TTTEPPKPTFPAYTQSTASTTSTTN--STAAKPAA--SITSKPATLTTTSATSKLIHPDE 353
P PT + + A + + +A PAA ++ + P T + ++ + P
Sbjct: 784 -----PIPTVVSGARGNAESGDSVKMYGSAVPPAAPTNLPTPPVTQPVSLLGTQGVAPGP 838
Query: 354 DISLEERRAQLPKYQRNLPRPGQAPIGNPPVGPIGGMMPPQ----PGIPQQQGMRPPMPP 409
I L Q P RPG P+ PP GM PP P +P + PMPP
Sbjct: 839 VIGL-----QAPSTGLLGARPGLIPLQRPP-----GMPPPHLQRFPLMPPR-----PMPP 883
Query: 410 HGQYGGHHQGMPGYLPGAMPPYGQGPPMVPPYQGGPPRPPMGMRPPVMSQG 460
H + G PP G G +PP P GM+ P G
Sbjct: 884 HMMHRG-------------PPPGPGGFAMPP--------PHGMKGPFPPHG 913
Score = 50.4 bits (119), Expect = 3e-06
Identities = 46/131 (35%), Positives = 54/131 (41%), Gaps = 15/131 (11%)
Query: 143 AQPGLPPVPGAPGMPPG------IPPLMPGVPPLMPGMPPVMPG---MPP--GLHHQRKY 191
A+PGL P+ PGMPP + P P P +M PP PG MPP G+
Sbjct: 852 ARPGLIPLQRPPGMPPPHLQRFPLMPPRPMPPHMMHRGPPPGPGGFAMPPPHGMKGPFPP 911
Query: 192 TQSFCGENIMMPMGGMMPPGPGIPPLMPG--MPPGMPPPVPRPGIPPMTQAQAVSAPGIL 249
F M +GG PGPG P G PP P P+P P Q Q P
Sbjct: 912 HGPFVRPGGMPGLGGP-GPGPGGPEDRDGRQQPPQQPQQQPQPQAPQQPQQQQQQQPPPS 970
Query: 250 NRPPAPTATVP 260
+PP PT P
Sbjct: 971 QQPP-PTQQQP 980
Score = 38.1 bits (87), Expect = 0.017
Identities = 57/242 (23%), Positives = 75/242 (30%), Gaps = 61/242 (25%)
Query: 224 GMPPPVPRPGIPPMTQAQAVSAPGILNRPPAPTATVPAPQPPVTK-------------PL 270
G PPP + P TQA S P + P + A T+ P
Sbjct: 153 GSPPPPVKVSSEPPTQATPNSVPAVPQLPSSDAFAAVAQLFQTTQGQQLQQILQTFQQPP 212
Query: 271 FPSAGQAQAAVQGPVGTDFKPLNSTPATTTEPPKPTFPAYTQSTA--------------- 315
P + AV V L +TP +E K FP Q TA
Sbjct: 213 KPQSPALDNAVMAQVQAITAQLKTTPTQPSEQ-KAAFPPPEQKTAFDKKLLDRFDYDDEP 271
Query: 316 -----------STTSTTNSTAAKPAASITSKPATLTTTSATSKLIHPDEDISLEERRAQL 364
+ +TT AA P A + PA +A+ P Q
Sbjct: 272 EAVEESKKEDTTAVTTTAPAAAVPPAPTATVPAAAAPAAASPP--PPQAPFGFPGDGMQQ 329
Query: 365 PKYQRNL---------------PRPGQAPIGNPPVG--PIGGMMPPQPGIPQQQGMRPPM 407
P Y ++ P Q P+ PP G P G++P P P Q + PP
Sbjct: 330 PAYTQHQNMDQFQPRMMGIQQDPMHHQVPL--PPNGQMPGFGLLPTPPFPPMAQPVIPPT 387
Query: 408 PP 409
PP
Sbjct: 388 PP 389
Score = 38.1 bits (87), Expect = 0.017
Identities = 44/149 (29%), Positives = 58/149 (38%), Gaps = 21/149 (14%)
Query: 98 EQKTQESQKKKQQDDSDEYDD-------DDSAASTSFQPQPVQPQQ--GYIPPMAQPGL- 147
EQKT +K + D D+ + +D+ A T+ P P +P A P
Sbjct: 252 EQKTAFDKKLLDRFDYDDEPEAVEESKKEDTTAVTTTAPAAAVPPAPTATVPAAAAPAAA 311
Query: 148 -PPVPGAPGMPPGIPPLMPGVPPL--MPGMPPVMPGMPPG-LHHQRKYTQSFCGENIMMP 203
PP P AP PG P M P M G+ +HHQ N MP
Sbjct: 312 SPPPPQAPFGFPGDGMQQPAYTQHQNMDQFQPRMMGIQQDPMHHQVPLPP-----NGQMP 366
Query: 204 MGGMMPPGPGIPPLMPGMPPGMPPPVPRP 232
G++P P P P +PP PPV +P
Sbjct: 367 GFGLLPTPPFPPMAQPVIPP--TPPVQQP 393
>gi|47132519 Ras association and pleckstrin homology domains 1 isoform
1 [Homo sapiens]
Length = 1250
Score = 77.8 bits (190), Expect = 2e-14
Identities = 90/367 (24%), Positives = 121/367 (32%), Gaps = 75/367 (20%)
Query: 124 STSFQPQPVQPQQGYIPPMAQPGLPPVPGAPGMPPGIPPLMPGVPPLMPGMPPVMPGMPP 183
S S +PQ + P G +PP P PP PG+ P P +P PP+
Sbjct: 694 SQSVKPQILVPPNGVVPPPPPPPPPPTPGSAMAQLKPAPCAPSLPQFSAPPPPLK----- 748
Query: 184 GLHHQRKYTQSFCGENIMMPMGGMMPPGPGIPPLMPGMPPGMPPPVPRPGIPPMTQAQAV 243
+H + TQ + PP P PP +P P PP P IP T + V
Sbjct: 749 -IHQVQHITQ-------------VAPPTPPPPPPIPAPLPPQAPPKPLVTIPAPTSTKTV 794
Query: 244 SAPGILNRPPAPTATVP----------------APQPPVTKPLFPSAGQAQAAVQGPVGT 287
+ PP PT VP P PPV P P+ + Q+ P +
Sbjct: 795 APVVTQAAPPTPTPPVPPAKKQPAFPASYIPPSPPTPPVPVPP-PTLPKQQSFCAKPPPS 853
Query: 288 DFKPLNST--PATTTEPPKPTFPAYTQSTASTTSTTNSTAAKPAASITSK--PATLTTTS 343
P+ S + PP PT PA + + PA K P+++ S
Sbjct: 854 PLSPVPSVVKQIASQFPPPPTPPAMESQPLKPVPANVAPQSPPAVKAKPKWQPSSIPVPS 913
Query: 344 ATSKLIHPDEDISLEERRAQLPKYQRNLPRPGQAPIGNPPVGPIGGMMPPQPGIPQQQ-- 401
PD E P P P P PP P P + G P ++
Sbjct: 914 -------PDFPPPPPESSLVFPP-----PPPSPVPAPPPPPPPTASPTPDKSGSPGKKTS 961
Query: 402 ------GMRPPMPPH------GQYGGHH-----QGMPGYLPGAMPPYGQGPP---MVPPY 441
G +PP P G H + + PP G P +PP
Sbjct: 962 KTSSPGGKKPPPTPQRNSSIKSSSGAEHPEPKRPSVDSLVSKFTPPAESGSPSKETLPP- 1020
Query: 442 QGGPPRP 448
PP+P
Sbjct: 1021 PAAPPKP 1027
Score = 75.5 bits (184), Expect = 1e-13
Identities = 104/394 (26%), Positives = 138/394 (35%), Gaps = 83/394 (21%)
Query: 102 QESQKKKQQDDSDEYDDDDSAASTSFQPQPVQPQQGYIPPM--AQPGLPPVPGAPGMPPG 159
+ES K + + + Y TS P P+ PQ + P +QP PP+P P PP
Sbjct: 588 EESSKARMESMNRPY--------TSLVP-PLSPQPKIVTPYTASQPS-PPLPPPPPPPPP 637
Query: 160 IPPLMPGVPPLMPGMPPVMPGMPPGLHHQRKYTQSFCGENIMMPMGGMM-PPGPG----- 213
PP P PP +P G + KY+ +N G + PP P
Sbjct: 638 PPPPPPPPPPPLPSQSAPSAGSAAPMF--VKYSTITRLQNASQHSGALFKPPTPPVMQSQ 695
Query: 214 -------IPPLMPGMPPGMPPPVPRPGIPPMTQAQAVSAPGI--LNRPPAP--------- 255
+PP PP PPP P PG A AP + + PP P
Sbjct: 696 SVKPQILVPPNGVVPPPPPPPPPPTPGSAMAQLKPAPCAPSLPQFSAPPPPLKIHQVQHI 755
Query: 256 ---TATVPAPQPPVTKPLFPSAGQAQAAVQGPVGTDFKPLNSTPATTTEPPKPTFPAYTQ 312
P P PP+ PL P A KPL + PA T+ K P TQ
Sbjct: 756 TQVAPPTPPPPPPIPAPLPPQAPP-------------KPLVTIPAPTS--TKTVAPVVTQ 800
Query: 313 STASTTSTTNSTAAK----PAASITSKPATLTTTSATSKLIHPDEDISLEERRAQLPKYQ 368
+ T + A K PA+ I P T P + LPK Q
Sbjct: 801 AAPPTPTPPVPPAKKQPAFPASYIPPSPPT------------PPVPVP----PPTLPKQQ 844
Query: 369 RNLPRPGQAPIGNPP--VGPIGGMMPPQPGIP--QQQGMRP-PMPPHGQYGGHHQGMPGY 423
+P +P+ P V I PP P P + Q ++P P Q + P +
Sbjct: 845 SFCAKPPPSPLSPVPSVVKQIASQFPPPPTPPAMESQPLKPVPANVAPQSPPAVKAKPKW 904
Query: 424 LPGAMPPYGQGPPMVPPYQG--GPPRPPMGMRPP 455
P ++P P PP PP PP + P
Sbjct: 905 QPSSIPVPSPDFPPPPPESSLVFPPPPPSPVPAP 938
>gi|19718731 bromodomain-containing protein 4 isoform long [Homo
sapiens]
Length = 1362
Score = 76.3 bits (186), Expect = 6e-14
Identities = 99/409 (24%), Positives = 134/409 (32%), Gaps = 72/409 (17%)
Query: 56 QVHKETIDAVPNAIPGRTDIELEIYGMEGIPEKDMDERRRLLEQKTQESQKKKQQDDSDE 115
Q K + A + + G + E E + + E + K + ++Q+
Sbjct: 682 QAEKVDVIAGSSKMKGFSSSESESSSESSSSDSEDSETEMAPKSKKKGHPGREQKKHHHH 741
Query: 116 YDDDDSAASTSFQPQPVQPQQGYIPP---MAQPGLPPVPGAPGMPPGIPPLMPGVPP--- 169
+ A QP P Q PP Q PP P P MP P M PP
Sbjct: 742 HHQQMQQAPAPVPQQPPPPPQQPPPPPPPQQQQQPPPPPPPPSMPQQAAPAMKSSPPPFI 801
Query: 170 --LMPGMPPVMPGMPPGLHHQRKYTQSFCGENIMMPMGGMMPPGPGIPPLMPGMPPGMPP 227
+P + P +PG ++ P+G P +P P +PP +P
Sbjct: 802 ATQVPVLEPQLPG------------------SVFDPIGHFTQPILHLP--QPELPPHLPQ 841
Query: 228 PVPRPGIPPMTQAQAVSAPGILN---RPPAPTATVPAPQPPVTKPLFPSAGQAQAAVQGP 284
P P + Q VS P + N + P+ + A PP KP P A + A Q P
Sbjct: 842 PPEHSTPPHLNQHAVVSPPALHNALPQQPSRPSNRAAALPP--KPARPPA-VSPALTQTP 898
Query: 285 VGTDFKPLNSTPATTTEPPKPTFPAYTQSTASTTSTTNSTAAKPAASITSKPATLTTTSA 344
+ P+ P E +P P T P + S
Sbjct: 899 L-LPQPPMAQPPQVLLEDEEPPAPPLTSMQMQLYLQQLQKVQPPTPLLPSVKVQSQPPPP 957
Query: 345 TSKLIHPDEDISLEERRAQLPKYQRNLPRPGQAPIGNPPVGPIGGMMPPQP-GIPQQQGM 403
HP L+++ PP P PPQP PQQQ
Sbjct: 958 LPPPPHPSVQQQLQQQ---------------------PPPPP-----PPQPQPPPQQQHQ 991
Query: 404 RPPMPPH---GQYGGHHQGMPGYLPGAMPPYGQGPPMVPPYQGGPPRPP 449
PP P H Q+ H Q P PP GQ PP PP Q PP P
Sbjct: 992 PPPRPVHLQPMQFSTHIQQPP-------PPQGQQPPHPPPGQQPPPPQP 1033
Score = 75.1 bits (183), Expect = 1e-13
Identities = 89/333 (26%), Positives = 113/333 (33%), Gaps = 61/333 (18%)
Query: 129 PQPVQPQQGYIPPMAQPGLPPVPGAPGMPPGIPPLMPGVPPLMP--GMPPVMPGMPPGLH 186
P P QP PP QP PP P PP PP PP MP P + PP +
Sbjct: 752 PVPQQPP----PPPQQPPPPPPPQQQQQPPPPPP-----PPSMPQQAAPAMKSSPPPFIA 802
Query: 187 HQRKYTQSFCGENIMMPMGGMMPPGPGIPPLMPGMPPGMPPPVPRPGIPPMTQAQAVSAP 246
Q + ++ P+G P +P P +PP +P P P + Q VS P
Sbjct: 803 TQVPVLEPQLPGSVFDPIGHFTQPILHLP--QPELPPHLPQPPEHSTPPHLNQHAVVSPP 860
Query: 247 GILN---RPPAPTATVPAPQPPVTKPLFPSAGQAQAAVQGPVGTDFKPLNSTPATTTEPP 303
+ N + P+ + A PP KP P A + A Q P+ P+ P E
Sbjct: 861 ALHNALPQQPSRPSNRAAALPP--KPARPPA-VSPALTQTPLLPQ-PPMAQPPQVLLEDE 916
Query: 304 KPTFPAYTQSTASTTSTTNSTAAKPAASITSKPATLTTTSATSKLIHPDEDISLEERRAQ 363
+P P T P + S HP L+++
Sbjct: 917 EPPAPPLTSMQMQLYLQQLQKVQPPTPLLPSVKVQSQPPPPLPPPPHPSVQQQLQQQ--- 973
Query: 364 LPKYQRNLPRPGQAPIGNPPVGPIGGMMPPQPGIP-QQQGMRPPMPPHGQYGGHHQGMPG 422
PP P PPQP P QQQ PP P H Q
Sbjct: 974 ------------------PPPPP-----PPQPQPPPQQQHQPPPRPVHLQ---------- 1000
Query: 423 YLPGAMPPYGQGPPMVPPYQGGPPRPPMGMRPP 455
P + Q PP PP PP PP G +PP
Sbjct: 1001 --PMQFSTHIQQPP--PPQGQQPPHPPPGQQPP 1029
Score = 57.8 bits (138), Expect = 2e-08
Identities = 79/328 (24%), Positives = 109/328 (33%), Gaps = 56/328 (17%)
Query: 134 PQQGYIPPMAQPGLPPVPGAP-GMPPGIP--PLMPGVPPLMPGM-------PPVMPGMPP 183
PQQ P LPP P P + P + PL+P P P PP P
Sbjct: 867 PQQPSRPSNRAAALPPKPARPPAVSPALTQTPLLPQPPMAQPPQVLLEDEEPPAPPLTSM 926
Query: 184 GLHHQRKYTQSFCGENIMMPMGGMM--PPGPGIPPLMPGM-------PPGMPPPVPRPGI 234
+ + Q ++P + PP P PP P + PP PPP P+P
Sbjct: 927 QMQLYLQQLQKVQPPTPLLPSVKVQSQPPPPLPPPPHPSVQQQLQQQPPPPPPPQPQP-- 984
Query: 235 PPMTQAQAVSAPGILN---------RPPAPTATVPAPQPPVTKPLFPSAGQAQAAVQ--- 282
PP Q Q P L +PP P P PP +P P + Q +Q
Sbjct: 985 PPQQQHQPPPRPVHLQPMQFSTHIQQPPPPQGQQPPHPPPGQQPPPPQPAKPQQVIQHHH 1044
Query: 283 -------GPVGTDFKPLNSTPATTTEPPKPTFPAYT-QSTASTTSTTNSTAAKPAASITS 334
P T +P P F + T QS + A+ +
Sbjct: 1045 SPRHHKSDPYSTGHLREAPSPLMIHSPQMSQFQSLTHQSPPQQNVQPKKQELRAASVVQP 1104
Query: 335 KPATLTTTSATSKLIHPDEDISLEERRAQLPKYQRNLPRPGQAP---------IGNPPVG 385
+P + I E S R + PK+ ++ P P +G P +
Sbjct: 1105 QPLVVVKEEKIHSPIIRSEPFS-PSLRPEPPKHPESIKAPVHLPQRPEMKPVDVGRPVIR 1163
Query: 386 PIGGMMPPQPGIP----QQQGMRPPMPP 409
P PP PG P Q+Q + P+ P
Sbjct: 1164 PPEQNAPP-PGAPDKDKQKQEPKTPVAP 1190
Score = 37.0 bits (84), Expect = 0.038
Identities = 42/158 (26%), Positives = 56/158 (35%), Gaps = 16/158 (10%)
Query: 231 RPGIPPMTQAQAVSAPGILNRP---PAPTATVPAPQPPVTKPLFPSAGQAQAAVQGPVGT 287
+PG+ + S P P P P P P P VT L VQ PV T
Sbjct: 190 KPGVSTVPNTTQASTPPQTQTPQPNPPPVQATPHPFPAVTPDLI---------VQTPVMT 240
Query: 288 DF--KPLNSTPATTTEPPKPTFPAYTQSTASTTSTTNSTAAKPAASITSKPATLTTTSAT 345
+PL + P +P P PA Q S +T K TTT T
Sbjct: 241 VVPPQPLQTPPPVPPQPQPPPAPA-PQPVQSHPPIIAATPQPVKTKKGVKRKADTTTPTT 299
Query: 346 SKLIHPDEDISLEERRAQLPKYQRNLPRPGQAPIGNPP 383
IH + E + +L + +R RP + P + P
Sbjct: 300 IDPIHEPPSLPPEPKTTKLGQ-RRESSRPVKPPKKDVP 336
Score = 36.6 bits (83), Expect = 0.049
Identities = 33/133 (24%), Positives = 48/133 (36%), Gaps = 10/133 (7%)
Query: 319 STTNSTAAKPAASITSKPATLTTTSATSKLIHPDEDISLEERRAQLPKYQRNLPRPGQAP 378
S++ S ++ ++S S+ + + K HP R Q + + + QAP
Sbjct: 699 SSSESESSSESSSSDSEDSETEMAPKSKKKGHPG--------REQKKHHHHHHQQMQQAP 750
Query: 379 IGNPPVGPIGGMMPPQPGIPQQQGMRPPMPPHGQYGGHHQGMPGYLPGAMPPYGQGPPMV 438
P P PP P PQQQ PP PP Q P P P++
Sbjct: 751 APVPQQPPPPPQQPPPPPPPQQQQQPPPPPPPPSM--PQQAAPAMKSSPPPFIATQVPVL 808
Query: 439 PPYQGGPPRPPMG 451
P G P+G
Sbjct: 809 EPQLPGSVFDPIG 821
Score = 33.5 bits (75), Expect = 0.42
Identities = 45/200 (22%), Positives = 61/200 (30%), Gaps = 43/200 (21%)
Query: 136 QGYIPPMAQ---PGLPPVPGAPGMPPGIPPLMPGVPPLMPGMPPVMPGMPPGLHHQRKYT 192
Q PP Q P PPV P P + P + P+M +PP PP
Sbjct: 201 QASTPPQTQTPQPNPPPVQATPHPFPAVTPDLIVQTPVMTVVPPQPLQTPP--------- 251
Query: 193 QSFCGENIMMPMGGMMPPGPGIPPLMPGMPPGMPPPVPRPGIPPMTQAQAVSAPGILNRP 252
+PP P PP P PP+ P+ + V
Sbjct: 252 --------------PVPPQPQPPPAPAPQPVQSHPPIIAATPQPVKTKKGVKRKA---DT 294
Query: 253 PAPTATVPAPQPPVTKPLFPSAGQAQAAVQGPVGTDFKPLNSTPATTTEPPKPTFPAYTQ 312
PT P +PP P + + G +P+ +PPK P Q
Sbjct: 295 TTPTTIDPIHEPPSLPP------EPKTTKLGQRRESSRPV--------KPPKKDVPDSQQ 340
Query: 313 STASTTSTTNSTAAKPAASI 332
A S+ S K + I
Sbjct: 341 HPAPEKSSKVSEQLKCCSGI 360
Score = 32.0 bits (71), Expect = 1.2
Identities = 22/49 (44%), Positives = 23/49 (46%), Gaps = 8/49 (16%)
Query: 416 HHQGM---PGYLPGAMPPYGQGPPMVPP--YQGGPPRPPMGMRPPVMSQ 459
HHQ M P +P PP Q PP PP Q PP PP PP M Q
Sbjct: 742 HHQQMQQAPAPVPQQPPPPPQQPPPPPPPQQQQQPPPPP---PPPSMPQ 787
Score = 29.3 bits (64), Expect = 7.9
Identities = 26/80 (32%), Positives = 31/80 (38%), Gaps = 21/80 (26%)
Query: 392 PPQPGIPQQQGMRPPMPPHGQYGGHHQGMPGYLPG---------AMPPYG-QGPPMVPPY 441
PPQ PQ P PP Q H P P +PP Q PP VPP
Sbjct: 205 PPQTQTPQ------PNPPPVQATPHP--FPAVTPDLIVQTPVMTVVPPQPLQTPPPVPPQ 256
Query: 442 QGGPPRP---PMGMRPPVMS 458
PP P P+ PP+++
Sbjct: 257 PQPPPAPAPQPVQSHPPIIA 276
>gi|149158690 HLA-B associated transcript-2 [Homo sapiens]
Length = 2157
Score = 75.9 bits (185), Expect = 7e-14
Identities = 107/386 (27%), Positives = 138/386 (35%), Gaps = 75/386 (19%)
Query: 98 EQKTQESQKKKQQDDSDEYDDDDSAASTSFQPQPVQP-QQGYIPPMAQPGLPP---VPGA 153
+++ QE K+QQ + SA T P P QP G +P P PP PGA
Sbjct: 648 QRQQQEQLLKQQQQHQWQQHQQGSAPPTPVPPSPPQPVTLGAVPAPQAPPPPPKALYPGA 707
Query: 154 PGMPPGIPP---------LMPGVPP-LMPGMPPVMPGMPPGLHHQR--KYTQSFCGENIM 201
G PP +PP + P V P L+ G PP + PPG+H +S G +
Sbjct: 708 LGRPPPMPPMNFDPRWMMIPPYVDPRLLQGRPP-LDFYPPGVHPSGLVPRERSDSGGSSS 766
Query: 202 MPMGGMMPP---GPGIPPLMP-----GMPPGMPPPVPRPGIPPMTQAQAVSAPGILNR-- 251
P P G PP+ P G P PRP P+ QA G+ +
Sbjct: 767 EPFDRHAPAMLRERGTPPVDPKLAWVGDVFTATPAEPRPLTSPLRQAADEDDKGMRSETP 826
Query: 252 ----PPAPTATVP------APQPPVTKPLFPSAGQAQAAVQGPVGTDFKPLNSTPATTTE 301
PP A+ P AP PP+++ FP + P G+D TP E
Sbjct: 827 PVPPPPPYLASYPGFPENGAPGPPISR--FPLEEPGPRPLPWPPGSDEVAKIQTPPPKKE 884
Query: 302 PPKPTFPAYTQSTASTTSTTNSTAAKPAASITS---KPATLTTTSATSKLIHPDEDISLE 358
PPK + TA T KPA + S P S T P S
Sbjct: 885 PPK-------EETAQLTGP--EAGRKPARGVGSGGQGPPPPRRESRTETRWGPRPGSS-- 933
Query: 359 ERRAQLPKYQRNLPRPGQAPIGNPPVGPIGGMMPPQPGIPQQQGMRPPMPP--------H 410
R +P + P PI PP +PP+ P +QG P PP
Sbjct: 934 --RRGIPPEEPGAPPRRAGPIKKPPPPTKVEELPPK---PLEQGDETPKPPKPDPLKITK 988
Query: 411 GQYGGHHQGMPGYLPGAMPPYGQGPP 436
G+ GG P PP G P
Sbjct: 989 GKLGG---------PKETPPNGNLSP 1005
Score = 62.0 bits (149), Expect = 1e-09
Identities = 107/426 (25%), Positives = 136/426 (31%), Gaps = 102/426 (23%)
Query: 98 EQKTQESQKKKQQDDSDEYDDDDSAASTSFQPQPVQPQQGYIPPMAQPGLPPVPGAPGMP 157
E++ E+ KK + E +A + + +P +P PP +P LPP P
Sbjct: 367 EERPPEADGKKGNSPNSEPPTPKTAWAETSRPPETEPG----PPAPKPPLPPPHRGPAGN 422
Query: 158 PGIPPLMP--GVPPLMPGMPPVMPGMPPGLHHQRKYTQS--------------------- 194
G P P G PP P P +RK + S
Sbjct: 423 WGPPGDYPDRGGPPCKP---PAPEDEDEAWRQRRKQSSSEISLAVERARRRREEEERRMQ 479
Query: 195 -----FCGENIMM---PMGG------MMPPGPGIPPLMPGMPPGMPPPVPRPGIPPMTQA 240
C E + G P P P P PP +P +P P PP
Sbjct: 480 EERRAACAEKLKRLDEKFGAPDKRLKAEPAAPPAAPSTPAPPPAVPKELPAPPAPP---- 535
Query: 241 QAVSAPGILNRPPAPTATVPAPQPPVTKPLFPSAGQAQAAVQGPVGTDFKPLNSTPATTT 300
SAP P P PA P P A V G T S A+
Sbjct: 536 -PASAPTPETEPEEPAQAPPAQSTPT-----PGVAAAPTLVSGGGSTSSTSSGSFEASPV 589
Query: 301 EPPKPTFPAYTQSTASTTSTTNSTAAKPAASITSKPATL--TTTSATSKLIHPDEDISL- 357
EP P+ TT P + K + T + L +P SL
Sbjct: 590 EPQLPSKEGPEPPEEVPPPTT-----PPVPKVEPKGDGIGPTRQPPSQGLGYPKYQKSLP 644
Query: 358 --------EERRAQLPKYQRNLPRPGQAPIGNPPVGPIGGMMPPQP----GIPQQQGMRP 405
E+ Q ++Q + G AP PV P PPQP +P Q P
Sbjct: 645 PRFQRQQQEQLLKQQQQHQWQQHQQGSAP--PTPVPP----SPPQPVTLGAVPAPQA--P 696
Query: 406 PMPPHGQYGGHHQGMPGYL--PGAMPPYGQGP--PMVPPY------QGGPPRPPMGMRPP 455
P PP Y PG L P MPP P M+PPY QG RPP+ PP
Sbjct: 697 PPPPKALY-------PGALGRPPPMPPMNFDPRWMMIPPYVDPRLLQG---RPPLDFYPP 746
Query: 456 VMSQGG 461
+ G
Sbjct: 747 GVHPSG 752
Score = 50.8 bits (120), Expect = 3e-06
Identities = 59/206 (28%), Positives = 77/206 (37%), Gaps = 18/206 (8%)
Query: 235 PPMTQAQAVSAPGILNRPPAPTATVPAPQPPVTKPLFPSAGQ--AQAAVQGPVGTDFKPL 292
PP +Q S N+P P P P PL PS + AQA+V D
Sbjct: 105 PPESQPLPASQTPASNQPKRP------PAAPENTPLVPSGVKSWAQASVTHGAHGDGGRA 158
Query: 293 NSTPATTTEPPKPTFPAY-TQSTASTTSTTNSTAAKPAASITSKPATLTTTSATSKLIHP 351
+S + + PT A Q A+ + ++ P S+ + +T P
Sbjct: 159 SSLLSRFSREEFPTLQAAGDQDKAAKERESAEQSSGPGPSLRPQNSTTWRDGGGRG---P 215
Query: 352 DEDISLEERRAQLPKYQRNLPRPGQAPIGNPPVGPIGGMMPPQPGIPQQQGMRPPMPPHG 411
DE LE ++L + + PR G P G P P GMMPP P PP P G
Sbjct: 216 DE---LEGPDSKL--HHGHDPRGGLQPSGPPQFPPYRGMMPPFM-YPPYLPFPPPYGPQG 269
Query: 412 QYGGHHQGMPGYLPGAMPPYGQGPPM 437
Y P P P G GPPM
Sbjct: 270 PYRYPTPDGPSRFPRVAGPRGSGPPM 295
Score = 40.4 bits (93), Expect = 0.003
Identities = 49/212 (23%), Positives = 80/212 (37%), Gaps = 34/212 (16%)
Query: 206 GMMPPG--------PGIPPLMPGMPPGMPPPVPRPGIPPMT---QAQAVSAPGILNRPPA 254
G +P G P + +P + G PP P P PP++ A+ P + RPP
Sbjct: 1968 GFLPSGAPAQQMLLPMVDSQLPVVNFGSLPPAPPPAPPPLSLLPVGPALQPPSLAVRPPP 2027
Query: 255 PTATVPAPQPPVTKPLFPSAGQAQAAVQGPVGTDFKPLNSTPATTTEPPKPTFPAYTQST 314
AT P P +P S G+A+ PV + KP F Y + +
Sbjct: 2028 APATRVLPSP--ARPFPASLGRAEL---HPV--ELKP---------------FQDYQKLS 2065
Query: 315 ASTTSTTNSTAAKPAASITSKPATLTTTSATSKLIHPDEDISLEERRAQLPKYQRNLPRP 374
++ +S S + + L T +T + + + L + +A P R +P+P
Sbjct: 2066 SNLGGPGSSRTPPTGRSFSGLNSRLKATPSTYSGVFRTQRVDLYQ-QASPPDALRWIPKP 2124
Query: 375 GQAPIGNPPVGPIGGMMPPQPGIPQQQGMRPP 406
+ P GP P ++ G+ PP
Sbjct: 2125 WERTGPPPREGPSRRAEEPGSRGDKEPGLPPP 2156
Score = 36.6 bits (83), Expect = 0.049
Identities = 108/483 (22%), Positives = 150/483 (31%), Gaps = 120/483 (24%)
Query: 66 PNAIPGRTDIELEIYGMEGIPEKDMDERRRLLEQKTQESQKKKQQDDSDEYDDDDSAAST 125
P A GRT E EG +++ +RRR Q+ E+ + + D D +
Sbjct: 1076 PPAPRGRTASETR---SEGSEYEEIPKRRR---QRGSETGSETHESDLAPSDKEAPTPKE 1129
Query: 126 SFQPQ-PVQPQQGYIPPMAQP------------------------GLPPVPGAPGMPP-- 158
Q P+ P PP P G PP PG P
Sbjct: 1130 GTLTQVPLAPPPPGAPPSPAPARFTARGGRVFTPRGVPSRRGRGGGRPPPQVCPGWSPPA 1189
Query: 159 -GIPPLMPGVPPLMPGMPPVMPGMPPGLHHQRKYTQSFCGENIMMPMGGMMPPGPGIPPL 217
+ P P PL P P+ + PG S G N+ M G P
Sbjct: 1190 KSLAPKKPPTGPLPPSKEPLKEKLIPGPLSPVARGGSNGGSNVGMEDG----ERPRRRRH 1245
Query: 218 MPGMPPGMPPPVPRPGIPPMTQAQAVSAPGILNRPPAP-TATVPAPQPPVTKPLFPSAGQ 276
PP R + Q + +A G +P A+ P P+ +T A +
Sbjct: 1246 GRAQQQDKPPRFRR-----LKQERENAARGSEGKPSLTLPASAPGPEEALTTVTVAPAPR 1300
Query: 277 AQAAVQGPVGTDFKPLNSTPATTTEPPKPTFPAYTQSTASTTSTTNSTAAKPAASITSKP 336
+AA + P D NS A + ++S+ T+ A P +T K
Sbjct: 1301 -RAAAKSP---DLSNQNSDQA------NEEWETASESSDFTSERRGDKEAPPPVLLTPKA 1350
Query: 337 ---------ATLTTTSATSK--LIHPDEDISLEERRAQLPKYQRNLPRPGQ--------- 376
+ SA S+ L +D+S +Q P +R RPG
Sbjct: 1351 VGTPGGGGGGAVPGISAMSRGDLSQRAKDLSKRSFSSQRPGMERQNRRPGPGGKAGSSGS 1410
Query: 377 -------APIGNPPVG---------PIGGMMPPQ---PGIPQQQGMRPPMPP-------- 409
P G G P PP+ PG+P PP PP
Sbjct: 1411 SSGGGGGGPGGRTGPGRGDKRSWPSPKNRSRPPEERPPGLP-----LPPPPPSSSAVFRL 1465
Query: 410 ----HGQYGGHHQGMPGY--------LPGAMPPYGQGPPMVPPYQGGPPRPPMGMRPPVM 457
H G Q + PG P + G P P QG PRPP P +
Sbjct: 1466 DQVIHSNPAGIQQALAQLSSRQGSVTAPGGHPRHKPGLPQAP--QGPSPRPPTRYEPQRV 1523
Query: 458 SQG 460
+ G
Sbjct: 1524 NSG 1526
Score = 34.3 bits (77), Expect = 0.25
Identities = 66/254 (25%), Positives = 89/254 (35%), Gaps = 51/254 (20%)
Query: 203 PMGGMMPPG-PGIPPLMPGMPPGM-PPPVPRPGIPPMTQAQAVSAPGILNRPPAPTATVP 260
P GG+ P G P PP MPP M PP +P P PP P R P P P
Sbjct: 231 PRGGLQPSGPPQFPPYRGMMPPFMYPPYLPFP--PPY-------GPQGPYRYPTPDG--P 279
Query: 261 APQPPVTKPLFPSAGQAQAAVQGPVG--TDFKPLNSTPATTTEPPKPTFPAYTQSTASTT 318
+ P V P +G V+ PVG + K N + A T
Sbjct: 280 SRFPRVAGP--RGSGPPMRLVE-PVGRPSILKEDNLKEFDQLDQENDDGWAGAHEEVDYT 336
Query: 319 STTNSTAAKPAASITSKPAT--LTTTSATSKLIHPDEDISLEERRAQLPKYQRNLPRPGQ 376
+ + + A + SA+ + P+ D ++ P + P+
Sbjct: 337 EKLKFSDEEDGRDSDEEGAEGHRDSQSASGEERPPEAD----GKKGNSPNSEPPTPKTAW 392
Query: 377 APIGNPPVGPIGGMMPPQPGIPQQQGMRPPMPPHGQYGGHHQGMPGYLPGAMPPYGQGPP 436
A PP G PP P +PP+PP H+G P GPP
Sbjct: 393 AETSRPPETEPG---PPAP--------KPPLPP------PHRG---------PAGNWGPP 426
Query: 437 MVPPYQGGPP-RPP 449
P +GGPP +PP
Sbjct: 427 GDYPDRGGPPCKPP 440
Score = 32.3 bits (72), Expect = 0.93
Identities = 28/96 (29%), Positives = 32/96 (33%), Gaps = 25/96 (26%)
Query: 154 PGMPPGIPPLMPGVPPLMPGMPPVMPGMPPGLHHQRKYTQSFCGENIMMPMGGMMPPGPG 213
P PP PP +PP M PP +P PP P G P P
Sbjct: 237 PSGPPQFPPYRGMMPPFM--YPPYLPFPPP-----------------YGPQGPYRYPTPD 277
Query: 214 IPPLMPGMPPGMPPPVPRPGIPPMTQAQAVSAPGIL 249
P P + PR PPM + V P IL
Sbjct: 278 GPSRFPRVAG------PRGSGPPMRLVEPVGRPSIL 307
Score = 31.2 bits (69), Expect = 2.1
Identities = 62/252 (24%), Positives = 88/252 (34%), Gaps = 30/252 (11%)
Query: 229 VPRPGIPPMTQAQAVSAPGILNRPPAPTATVPAPQ-------PPVTKPLFPSAGQAQAAV 281
+ +P + P Q++ I R P P A +P+ + P V+ L P G A+
Sbjct: 33 IQKPAVAPRHGLQSLGKVAIARRMPPP-ANLPSLKAENKGNDPNVS--LVPKDGTGWASK 89
Query: 282 QGPVGTDFKPLNSTPATTTEPPKPTFPAYTQSTASTTSTTNSTAAKPAASITSKPATLTT 341
Q + S+ A+T +PP+ +Q+ AS A + + S +
Sbjct: 90 Q-----EQSDPKSSDASTAQPPESQPLPASQTPASNQPKRPPAAPENTPLVPSGVKSWAQ 144
Query: 342 TSATSKLIHPD--EDISLEER--RAQLPKYQRNLPRPGQAP---IGNPPVGPIGGMMPPQ 394
S T H D SL R R + P Q + A GP + P
Sbjct: 145 ASVTHGA-HGDGGRASSLLSRFSREEFPTLQAAGDQDKAAKERESAEQSSGPGPSLRPQN 203
Query: 395 PGIPQQQGMRPPMPPHGQYGGHHQGMPGYLPGAMPPYGQGPPMVPPYQGGPP---RPPMG 451
+ G R P G H G G + P GPP PPY+G P PP
Sbjct: 204 STTWRDGGGRGPDELEGPDSKLHHGHDPR--GGLQP--SGPPQFPPYRGMMPPFMYPPYL 259
Query: 452 MRPPVMSQGGRY 463
PP G Y
Sbjct: 260 PFPPPYGPQGPY 271
>gi|117306167 proline-rich protein BstNI subfamily 3 precursor [Homo
sapiens]
Length = 309
Score = 75.9 bits (185), Expect = 7e-14
Identities = 97/376 (25%), Positives = 117/376 (31%), Gaps = 112/376 (29%)
Query: 110 QDDSDEYDDDDSAASTSFQPQPVQPQQGYIPPMAQP------GLPPVPGAPGMPPGIPPL 163
Q +++ ++S + S +P+ +PQ G P P G PP G P P
Sbjct: 17 QSLNEDVSQEESPSVISGKPEGRRPQGGNQPQRTPPPPGKPEGRPPQGGNQSQGPPPRPG 76
Query: 164 MPGVPPLMPGM----PPVMPGMPPGLHHQRKYTQSFCGENIMMPMGGMMPPGPGIPPLMP 219
P PP G PP PG P G P GG G PP P
Sbjct: 77 KPEGPPPQGGNQSQGPPPRPGKPEG----------------QPPQGGNQSQG---PPPRP 117
Query: 220 GMPPGMPP--------PVPRPGIPPMTQAQAVSAPGILNRPPAPTATVPAPQPPVTKPLF 271
G P G PP P PRPG P Q G ++ P P P PP
Sbjct: 118 GKPEGPPPQGGNQSQGPPPRPGKPEGPPPQG----GNQSQGPPPRPGKPEGPPP------ 167
Query: 272 PSAGQAQAAVQGPVGTDFKPLNSTPATTTEPPKPTFPAYTQSTASTTSTTNSTAAKPAAS 331
Q+Q P + P + PP+P P S
Sbjct: 168 QGGNQSQGPPPHPGKPEGPPPQGGNQSQGPPPRPGKPEGPPPQGGNQS------------ 215
Query: 332 ITSKPATLTTTSATSKLIHPDEDISLEERRAQLPKYQRNLPRPGQAPIGNPPVGPIGGMM 391
Q P + P + GN P GP
Sbjct: 216 -------------------------------QGPPPRPGKPEGPPSQGGNKPQGP----- 239
Query: 392 PPQPGIPQ----QQGMRPPMPPHGQYGGHHQGMPGYLPGAMPPYGQGPPMVPPYQG---G 444
PP PG PQ Q+G +P PP PG G PP G +PP G G
Sbjct: 240 PPHPGKPQGPPPQEGNKPQRPP----------PPGRPQGPPPPGGNPQQPLPPPAGKPQG 289
Query: 445 PPRPPMGMRPPVMSQG 460
PP PP G RP QG
Sbjct: 290 PPPPPQGGRPHRPPQG 305
Score = 46.6 bits (109), Expect = 5e-05
Identities = 48/122 (39%), Positives = 51/122 (41%), Gaps = 35/122 (28%)
Query: 372 PRPGQAPIGNPPVGPIGGM-MPPQPGIP---------QQQGMRP----PMPPHGQYGGHH 417
PRPG+ P G PP G PP+PG P Q QG P P P Q G
Sbjct: 115 PRPGK-PEGPPPQGGNQSQGPPPRPGKPEGPPPQGGNQSQGPPPRPGKPEGPPPQGGNQS 173
Query: 418 QGMPGY--LPGAMPPYG----QGP------PMVPPYQGG------PPRPPMGMRPPVMSQ 459
QG P + P PP G QGP P PP QGG PPRP PP SQ
Sbjct: 174 QGPPPHPGKPEGPPPQGGNQSQGPPPRPGKPEGPPPQGGNQSQGPPPRPGKPEGPP--SQ 231
Query: 460 GG 461
GG
Sbjct: 232 GG 233
Score = 45.4 bits (106), Expect = 1e-04
Identities = 54/155 (34%), Positives = 60/155 (38%), Gaps = 44/155 (28%)
Query: 337 ATLTTTSATSKLIHPDEDISLEE-----------RRAQLPKYQRNLPRPGQAPIGNPPVG 385
A L +SA S +ED+S EE RR Q + P P P G PP G
Sbjct: 9 ALLALSSAQSL----NEDVSQEESPSVISGKPEGRRPQGGNQPQRTPPPPGKPEGRPPQG 64
Query: 386 PIGGM-MPPQPGIPQQQGMRPPMPPHGQYGGHHQGMPGY--LPGAMPPYG----QGPPMV 438
PP+PG P+ PP G G QG P P PP G QGPP
Sbjct: 65 GNQSQGPPPRPGKPEGP------PPQG--GNQSQGPPPRPGKPEGQPPQGGNQSQGPPPR 116
Query: 439 P------PYQGG------PPRPPMGMRPPVMSQGG 461
P P QGG PPRP PP QGG
Sbjct: 117 PGKPEGPPPQGGNQSQGPPPRPGKPEGPP--PQGG 149
Score = 44.3 bits (103), Expect = 2e-04
Identities = 48/142 (33%), Positives = 52/142 (36%), Gaps = 37/142 (26%)
Query: 129 PQPVQPQQGYIPPMA---QPGLPPVPGAPGMPPGIPPLMPGVPPLMPGMPPVMPGMPP-- 183
P+P +P+ PP G PP PG P PP P PP PG P G PP
Sbjct: 199 PRPGKPEGP--PPQGGNQSQGPPPRPGKPEGPPSQGGNKPQGPPPHPGKP---QGPPPQE 253
Query: 184 GLHHQRKYTQSFCGENIMMPMGGMMPPGPGIPPLMPGMPPGMPPPVPRPGIPPMTQAQAV 243
G QR PP PG P P PPG P P P PP + Q
Sbjct: 254 GNKPQR-------------------PPPPGRPQGPP--PPGGNPQQPLP--PPAGKPQGP 290
Query: 244 SAPGILNRPPAPTATVPAPQPP 265
P RP P P QPP
Sbjct: 291 PPPPQGGRPHRP----PQGQPP 308
Score = 30.0 bits (66), Expect = 4.6
Identities = 20/51 (39%), Positives = 22/51 (43%), Gaps = 3/51 (5%)
Query: 128 QPQPVQPQQGYIPPMAQPGLPPVPGAPGMPPGIPPLMPGVPPLMP--GMPP 176
+P P QG PP P P+P G P G PP G P P G PP
Sbjct: 259 RPPPPGRPQGPPPPGGNP-QQPLPPPAGKPQGPPPPPQGGRPHRPPQGQPP 308
>gi|46852161 methyl-CpG binding domain protein 6 [Homo sapiens]
Length = 1003
Score = 75.1 bits (183), Expect = 1e-13
Identities = 101/376 (26%), Positives = 132/376 (35%), Gaps = 71/376 (18%)
Query: 146 GLPPVPGAPGMPPGIPPLMPGVPPLMPGMPPVMPGMP--PGLHHQRKYTQSFCGENIMM- 202
G PP P A PP PPL L P P +P PG Q + + +++
Sbjct: 243 GSPPAPHASSSPPSDPPLFHCSDALTPPPLPPSNNLPAHPGPASQPPVSSATMHLPLVLG 302
Query: 203 PMGGMMP-PGPGIPPLMPG---------MPPGMPPPVPRPGIPPMTQAQAVSAPGILN-- 250
P+GG GPG PP + P +PPP G P QA + S L
Sbjct: 303 PLGGAPTVEGPGAPPFLASSLLSAAAKAQHPPLPPPSTLQGRRPRAQAPSASHSSSLRPS 362
Query: 251 -----RPPA-----------------PTATVPAPQP----PVTKPLFPSA-GQAQAAVQG 283
RPP P A P PQP ++P+ PS G
Sbjct: 363 QRRPRRPPTVFRLLEGRGPQTPRRSRPRAPAPVPQPFSLPEPSQPILPSVLSLLGLPTPG 422
Query: 284 PVGTD--FKPLNST-----PATTTE--PPKPTFPAYTQSTASTTSTTNSTAAKPAASITS 334
P +D F L S P T + PP+P P +T+ + +S PA S
Sbjct: 423 PSHSDGSFNLLGSDAHLPPPPTLSSGSPPQPRHPIQPSLPGTTSGSLSSVPGAPAPPAAS 482
Query: 335 KPATLTTTSATSKLIHPDEDISLEERRA-QLPKYQRNLPRPGQAPIGNPPVGPIG--GMM 391
K + + S P E + + A LP P +P + G GM+
Sbjct: 483 KAPVVPSPVLQS----PSEGLGMGAGPACPLPPLAGGEAFPFPSPEQGLALSGAGFPGML 538
Query: 392 PPQPGIPQQQGMRPPMP--PHGQYG--GHHQGMPGYLPGAMPPYGQGPPMVPPYQGGP-- 445
P +P G PP P H +G G P P PP G GPP+ P GP
Sbjct: 539 GALP-LPLSLGQPPPSPLLNHSLFGVLTGGGGQPPPEPLLPPPGGPGPPLAPGEPEGPSL 597
Query: 446 ------PRPPMGMRPP 455
P PP + PP
Sbjct: 598 LVASLLPPPPSDLLPP 613
Score = 61.2 bits (147), Expect = 2e-09
Identities = 107/442 (24%), Positives = 145/442 (32%), Gaps = 117/442 (26%)
Query: 113 SDEYDDDDSAASTSFQPQPVQPQQGYIPPMAQPGLPPVPGAPGMP-----PGIP------ 161
SD + S+ PQP P Q +P L VPGAP P P +P
Sbjct: 435 SDAHLPPPPTLSSGSPPQPRHPIQPSLPGTTSGSLSSVPGAPAPPAASKAPVVPSPVLQS 494
Query: 162 ----------PLMPGVPPLMPGMPPVMPGMPPGLHHQRKYTQSFCGENIMMPMG-GMMPP 210
P P +PPL G P GL G + +P+ G PP
Sbjct: 495 PSEGLGMGAGPACP-LPPLAGGEAFPFPSPEQGLALSGAGFPGMLGA-LPLPLSLGQPPP 552
Query: 211 GP--------------GIPPLMPGM-PPGMPPPVPRPGIPPMTQAQAVSAPGILNRPPAP 255
P G PP P + PPG P P PG P + ++ +L PP P
Sbjct: 553 SPLLNHSLFGVLTGGGGQPPPEPLLPPPGGPGPPLAPGEP---EGPSLLVASLL--PPPP 607
Query: 256 TATVPAPQPPVTK---------PLFPSAGQAQAAVQGPVGTD--------------FKPL 292
+ +P P P + L P+AG + + +G G F PL
Sbjct: 608 SDLLPPPSAPPSNLLASFLPLLALGPTAGDGEGSAEGAGGPSGEPFSGLGDLSPLLFPPL 667
Query: 293 NSTP----------ATTTEPPKPTFP-----AYTQSTASTTSTTNSTAAKPAASITSKPA 337
++ P A T +PP T P + Q T+S T +T A+S+ P
Sbjct: 668 SAPPTLIALNSALLAATLDPPSGTPPQPCVLSAPQPGPPTSSVTTATTDPGASSLGKAP- 726
Query: 338 TLTTTSATSKLIHPDEDISLEERRAQLPKYQRNLPRPGQAPIGNPPVGPI---------- 387
+ + +L+ P SL + L PG P P GP+
Sbjct: 727 --SNSGRPPQLLSPLLGASLLGDLSSLTS------SPGALPSLLQPPGPLLSGQLGLQLL 778
Query: 388 --GGMMPP-------------QPGIPQQQGMRPPMPPHGQYGG-HHQGMPGYLPGAMPPY 431
GG PP IP +Q P +PP + L PP+
Sbjct: 779 PGGGAPPPLSEASSPLACLLQSLQIPPEQPEAPCLPPESPASALEPEPARPPLSALAPPH 838
Query: 432 GQGPPMVPPYQGGPPRPPMGMR 453
G P VP G G R
Sbjct: 839 GSPDPPVPELLTGRGSGKRGRR 860
Score = 58.2 bits (139), Expect = 2e-08
Identities = 88/369 (23%), Positives = 116/369 (31%), Gaps = 79/369 (21%)
Query: 140 PPMAQPGLPPVPGAPGMPPGIPPLMPGVPPLMPGMPPVMPGMPPGLHHQRKYTQSFCGEN 199
PP P P+ G PG P PP + P + G P GL R G +
Sbjct: 147 PPCRVPPTTPLNGGPGSLPPEPPSVSQAFPTLAG--------PGGLFPPRLADPVPSGGS 198
Query: 200 I---MMPMGGMMPPGPGIPPLMPGMPPGM----------------PPPVPRPGIPPMTQA 240
+P G P P PP + P PP P P +
Sbjct: 199 SSPRFLPRGNAPSPAPPPPPAISLNAPSYNWGAALRSSLVPSDLGSPPAPHASSSPPSDP 258
Query: 241 QAVSAPGILNRPPAPTAT------VPAPQPPVTK-----PLFPSAGQAQAAVQGPVGTDF 289
L PP P + PA QPPV+ PL V+GP F
Sbjct: 259 PLFHCSDALTPPPLPPSNNLPAHPGPASQPPVSSATMHLPLVLGPLGGAPTVEGPGAPPF 318
Query: 290 --KPLNSTPATTTEPPKPTFPAYTQS---TASTTSTTNSTAAKPAASITSKPATLTTTSA 344
L S A PP P P+ Q A S ++S++ +P+ +P T+
Sbjct: 319 LASSLLSAAAKAQHPPLPP-PSTLQGRRPRAQAPSASHSSSLRPSQRRPRRPPTVFRL-- 375
Query: 345 TSKLIHPDEDISLEERRAQLPKYQR-NLPRPGQAPIGNPPVGPIGGMMPPQPGIPQQQGM 403
LE R Q P+ R P P P P P P + G+
Sbjct: 376 ------------LEGRGPQTPRRSRPRAPAPVPQPFSLPEPS-----QPILPSVLSLLGL 418
Query: 404 RPPMPPHGQYGGHHQGMPGYLP------GAMPPYGQGP--PMVPPYQG-------GPPRP 448
P P H + G +LP PP + P P +P G P P
Sbjct: 419 PTPGPSHSDGSFNLLGSDAHLPPPPTLSSGSPPQPRHPIQPSLPGTTSGSLSSVPGAPAP 478
Query: 449 PMGMRPPVM 457
P + PV+
Sbjct: 479 PAASKAPVV 487
>gi|55750053 atrophin-1 [Homo sapiens]
Length = 1190
Score = 73.9 bits (180), Expect = 3e-13
Identities = 110/418 (26%), Positives = 148/418 (35%), Gaps = 106/418 (25%)
Query: 117 DDDDSAASTSFQPQPVQPQQGYIPPMAQPGLPPVPGAPGMPPGIPPLMPG-------VPP 169
D SF+P P GY PM P PG PP P L PG PP
Sbjct: 173 DSTPRQPEASFEPHPSVTPTGYHAPMEPPTSRMFQAPPGAPPPHPQLYPGGTGGVLSGPP 232
Query: 170 LMP---GMPPVMPGMPPGLHHQRKYTQ---SFCGENIMMPM--------GGMMPPGPGIP 215
+ P G + G G H T S G + P GG +P P P
Sbjct: 233 MGPKGGGAASSVGGPNGGKQHPPPTTPISVSSSGASGAPPTKPPTTPVGGGNLPSAPP-P 291
Query: 216 PLMPGMPPGMPPPVPRPGIPPMTQAQAVSAPGILNRPPAPTATVPAPQPPVTKPLFPSAG 275
P + P +PPP P + P+ A A S PG L P P +P+P + G
Sbjct: 292 ANFPHVTPNLPPP---PALRPLNNASA-SPPG-LGAQPLP-GHLPSPH---------AMG 336
Query: 276 QAQAAVQGPVGTDFKPL-----NSTPATTTEPPKPTFPAYTQSTASTTSTTNSTAAKPAA 330
Q + P G + P +S P ++ P P S++S+++ +S+++ ++
Sbjct: 337 QGMGGL--PPGPEKGPTLAPSPHSLPPASSSAPAPPMRFPYSSSSSSSAAASSSSSSSSS 394
Query: 331 SITSKPATLTTTSATSKLIHPDEDISLEERRAQLPKY-QRNLPRPGQAPIGNPPVGPIG- 388
S + PA+ S P +S+ Q PKY Q +LP G PP P G
Sbjct: 395 SASPFPASQALPSYPHS-FPPPTSLSVSN---QPPKYTQPSLPSQAVWSQGPPPPPPYGR 450
Query: 389 ---------GMMPPQPGIP--------------QQQGMR-------------------PP 406
G PP G QQQ + PP
Sbjct: 451 LLANSNAHPGPFPPSTGAQSTAHPPVSTHHHHHQQQQQQQQQQQQQQQQQQQHHGNSGPP 510
Query: 407 MP---PHGQYGG--HHQGMPGYLP--GAMPPYGQGPPMVPP-------YQGGPPRPPM 450
P PH GG HH P G++ PY GP +PP Q GP PP+
Sbjct: 511 PPGAFPHPLEGGSSHHAHPYAMSPSLGSLRPYPPGPAHLPPPHSQVSYSQAGPNGPPV 568
Score = 55.8 bits (133), Expect = 8e-08
Identities = 82/342 (23%), Positives = 105/342 (30%), Gaps = 51/342 (14%)
Query: 126 SFQPQPVQPQQGYIPPMAQPGLPPVPGAPGMPPGIPPL---------MPG-VPPLMPGMP 175
SF P P QP LP PP PP PG PP
Sbjct: 411 SFPPPTSLSVSNQPPKYTQPSLPSQAVWSQGPPPPPPYGRLLANSNAHPGPFPPSTGAQS 470
Query: 176 PVMPGMPPGLHH-----QRKYTQSFCGENIMMPMGGMMPPGPGI--PPLMPGMPPGMPPP 228
P + HH Q++ Q + G PP PG PL G P
Sbjct: 471 TAHPPVSTHHHHHQQQQQQQQQQQQQQQQQQQHHGNSGPPPPGAFPHPLEGGSSHHAHPY 530
Query: 229 VPRPGIPPMTQAQAVSAPGILNRPPAPTATVPAPQPPVTKPLFPSAGQAQAAVQGPVGTD 288
P + + PG + PP + + P P+ S+ + + QG
Sbjct: 531 AMSPSLGSLRPYP----PGPAHLPPPHSQVSYSQAGPNGPPVSSSSNSSSSTSQGSYPCS 586
Query: 289 FKPLNSTPATTTEPPKPTFPAYTQSTASTTSTTNSTAAKPAASITSKPATLTTTSATSKL 348
P S P P P T S+A+ ++ + A+ PA T+ P
Sbjct: 587 H-PSPSQGPQGAPYPFPPVPTVTTSSATLSTVIATVASSPAGYKTASP------------ 633
Query: 349 IHPDEDISLEERRAQLPKYQRNLPRPGQAPIGNPPVGPIGGMMPPQPGIPQQQGMRPPMP 408
P Y + P PG PP G PP G R P
Sbjct: 634 -------------PGPPPYGKRAPSPGAYKTATPPGYKPGS--PPSFRTGTPPGYRGTSP 678
Query: 409 PHGQYGGHHQGMPGYLPGAMPPYG-QGPPMVPPYQGGPPRPP 449
P G G G P PG +PP G G P +PP P P
Sbjct: 679 PAGP-GTFKPGSPTVGPGPLPPAGPSGLPSLPPPPAAPASGP 719
Score = 55.8 bits (133), Expect = 8e-08
Identities = 80/303 (26%), Positives = 107/303 (35%), Gaps = 51/303 (16%)
Query: 157 PPGIPPL-----MPGV------PPLMPGMPPVM-PGMPPGLHHQRKYTQSFCGENIMMPM 204
PPG PP PG P PG PP G PPG + T G P
Sbjct: 633 PPGPPPYGKRAPSPGAYKTATPPGYKPGSPPSFRTGTPPGY----RGTSPPAGPGTFKPG 688
Query: 205 GGMMPPGPGIPPLMP-GMPPGMPPPVPRPGIPPMTQAQAVSAPGILNRPPAPTATVPAPQ 263
+ PGP +PP P G+P PPP PP+ SA I P T +P
Sbjct: 689 SPTVGPGP-LPPAGPSGLPSLPPPPAAPASGPPL------SATQIKQEPAEEYETPESPV 741
Query: 264 PPVTKPLFPSAGQAQAAVQGPVGTDFKPLNSTPATTTEPPKPTFPAYTQSTASTTSTTNS 323
PP P P P D S A + F + +S S
Sbjct: 742 PPARSPSPP-----------PKVVDVPSHASQSARFNKHLDRGFNSCARSDLYFVPLEGS 790
Query: 324 TAAKPAASITSKPATLTTTSA-TSKLIHPDEDISLEERRAQLPKYQRN--LPRPGQAPIG 380
AK A + K A K + + E R + + +R+ L + G+AP+
Sbjct: 791 KLAKKRADLVEKVRREAEQRAREEKEREREREREKEREREKERELERSVKLAQEGRAPVE 850
Query: 381 NPPVGPIGGMMPPQPG-----IPQQQGM-RPPMPPHGQYGGHHQGMPG------YLP-GA 427
P +GP+ P +PG +P G P + +Y H PG Y+P GA
Sbjct: 851 CPSLGPVPHRPPFEPGSAVATVPPYLGPDTPALRTLSEYARPHVMSPGNRNHPFYVPLGA 910
Query: 428 MPP 430
+ P
Sbjct: 911 VDP 913
Score = 49.7 bits (117), Expect = 6e-06
Identities = 62/251 (24%), Positives = 80/251 (31%), Gaps = 50/251 (19%)
Query: 216 PLMPGMPPGMPPPVPRP--GIPPMTQAQAVSAPGI--------LNRPPAPTATVPAPQPP 265
P P PP + PP P+P P +A P + + P + P PP
Sbjct: 155 PARPYHPPPLFPPSPQPPDSTPRQPEASFEPHPSVTPTGYHAPMEPPTSRMFQAPPGAPP 214
Query: 266 VTKPLFP--SAGQAQAAVQGPVGTDFKPLNSTPATTTEPPKPTFPAYTQSTASTTSTTNS 323
L+P + G GP G P + P PT P + S++ +
Sbjct: 215 PHPQLYPGGTGGVLSGPPMGPKGGGAASSVGGPNGGKQHPPPTTPI-------SVSSSGA 267
Query: 324 TAAKPAASITSKPATLTTTSATSKLIHPDEDISLEERRAQLPKYQRNL-PRPGQAPIGNP 382
+ A P +KP T P A P NL P P P+ N
Sbjct: 268 SGAPP-----TKPPTTPVGGGNLPSAPPP---------ANFPHVTPNLPPPPALRPLNNA 313
Query: 383 PVGPIGGMMPPQPG-IPQQQGMRPPMPPHGQYGGHHQGMPGYLPGAM--PPYGQGPPMVP 439
P G P PG +P M QGM G PG P P +P
Sbjct: 314 SASPPGLGAQPLPGHLPSPHAM-------------GQGMGGLPPGPEKGPTLAPSPHSLP 360
Query: 440 PYQGGPPRPPM 450
P P PPM
Sbjct: 361 PASSSAPAPPM 371
Score = 34.3 bits (77), Expect = 0.25
Identities = 46/220 (20%), Positives = 83/220 (37%), Gaps = 63/220 (28%)
Query: 90 MDERRRLLEQKTQESQKKKQQDDSDEYDDDDSAASTSFQPQPVQPQQGYIPPMAQPGLPP 149
+++ RR EQ+ +E ++++++ + ++ + + + V+ Q P+ P L P
Sbjct: 800 VEKVRREAEQRAREEKEREREREREKEREREKERELE---RSVKLAQEGRAPVECPSLGP 856
Query: 150 VPGAPGMPPG-----IPPLM-PGVPPLM----------------------------PGM- 174
VP P PG +PP + P P L PG+
Sbjct: 857 VPHRPPFEPGSAVATVPPYLGPDTPALRTLSEYARPHVMSPGNRNHPFYVPLGAVDPGLL 916
Query: 175 ----PPVMPGMPPGLHHQRKYTQSFCGENI----------MMPMGGMMPPGPGIPP---- 216
P + P +R+ + + + + P+ G+ PGPG+ P
Sbjct: 917 GYNVPALYSSDPAAREREREARERDLRDRLKPGFEVKPSELEPLHGV--PGPGLDPFPRH 974
Query: 217 ----LMPGMPPGMPPPVPRPGIPPMTQAQAVSAPGILNRP 252
L PG PPG+ P P + P+ + + A G RP
Sbjct: 975 GGLALQPG-PPGLHPFPFHPSLGPLERERLALAAGPALRP 1013
Score = 30.8 bits (68), Expect = 2.7
Identities = 15/42 (35%), Positives = 19/42 (45%)
Query: 122 AASTSFQPQPVQPQQGYIPPMAQPGLPPVPGAPGMPPGIPPL 163
A +F+P G +PP GLP +P P P PPL
Sbjct: 680 AGPGTFKPGSPTVGPGPLPPAGPSGLPSLPPPPAAPASGPPL 721
>gi|55750041 atrophin-1 [Homo sapiens]
Length = 1190
Score = 73.9 bits (180), Expect = 3e-13
Identities = 110/418 (26%), Positives = 148/418 (35%), Gaps = 106/418 (25%)
Query: 117 DDDDSAASTSFQPQPVQPQQGYIPPMAQPGLPPVPGAPGMPPGIPPLMPG-------VPP 169
D SF+P P GY PM P PG PP P L PG PP
Sbjct: 173 DSTPRQPEASFEPHPSVTPTGYHAPMEPPTSRMFQAPPGAPPPHPQLYPGGTGGVLSGPP 232
Query: 170 LMP---GMPPVMPGMPPGLHHQRKYTQ---SFCGENIMMPM--------GGMMPPGPGIP 215
+ P G + G G H T S G + P GG +P P P
Sbjct: 233 MGPKGGGAASSVGGPNGGKQHPPPTTPISVSSSGASGAPPTKPPTTPVGGGNLPSAPP-P 291
Query: 216 PLMPGMPPGMPPPVPRPGIPPMTQAQAVSAPGILNRPPAPTATVPAPQPPVTKPLFPSAG 275
P + P +PPP P + P+ A A S PG L P P +P+P + G
Sbjct: 292 ANFPHVTPNLPPP---PALRPLNNASA-SPPG-LGAQPLP-GHLPSPH---------AMG 336
Query: 276 QAQAAVQGPVGTDFKPL-----NSTPATTTEPPKPTFPAYTQSTASTTSTTNSTAAKPAA 330
Q + P G + P +S P ++ P P S++S+++ +S+++ ++
Sbjct: 337 QGMGGL--PPGPEKGPTLAPSPHSLPPASSSAPAPPMRFPYSSSSSSSAAASSSSSSSSS 394
Query: 331 SITSKPATLTTTSATSKLIHPDEDISLEERRAQLPKY-QRNLPRPGQAPIGNPPVGPIG- 388
S + PA+ S P +S+ Q PKY Q +LP G PP P G
Sbjct: 395 SASPFPASQALPSYPHS-FPPPTSLSVSN---QPPKYTQPSLPSQAVWSQGPPPPPPYGR 450
Query: 389 ---------GMMPPQPGIP--------------QQQGMR-------------------PP 406
G PP G QQQ + PP
Sbjct: 451 LLANSNAHPGPFPPSTGAQSTAHPPVSTHHHHHQQQQQQQQQQQQQQQQQQQHHGNSGPP 510
Query: 407 MP---PHGQYGG--HHQGMPGYLP--GAMPPYGQGPPMVPP-------YQGGPPRPPM 450
P PH GG HH P G++ PY GP +PP Q GP PP+
Sbjct: 511 PPGAFPHPLEGGSSHHAHPYAMSPSLGSLRPYPPGPAHLPPPHSQVSYSQAGPNGPPV 568
Score = 55.8 bits (133), Expect = 8e-08
Identities = 82/342 (23%), Positives = 105/342 (30%), Gaps = 51/342 (14%)
Query: 126 SFQPQPVQPQQGYIPPMAQPGLPPVPGAPGMPPGIPPL---------MPG-VPPLMPGMP 175
SF P P QP LP PP PP PG PP
Sbjct: 411 SFPPPTSLSVSNQPPKYTQPSLPSQAVWSQGPPPPPPYGRLLANSNAHPGPFPPSTGAQS 470
Query: 176 PVMPGMPPGLHH-----QRKYTQSFCGENIMMPMGGMMPPGPGI--PPLMPGMPPGMPPP 228
P + HH Q++ Q + G PP PG PL G P
Sbjct: 471 TAHPPVSTHHHHHQQQQQQQQQQQQQQQQQQQHHGNSGPPPPGAFPHPLEGGSSHHAHPY 530
Query: 229 VPRPGIPPMTQAQAVSAPGILNRPPAPTATVPAPQPPVTKPLFPSAGQAQAAVQGPVGTD 288
P + + PG + PP + + P P+ S+ + + QG
Sbjct: 531 AMSPSLGSLRPYP----PGPAHLPPPHSQVSYSQAGPNGPPVSSSSNSSSSTSQGSYPCS 586
Query: 289 FKPLNSTPATTTEPPKPTFPAYTQSTASTTSTTNSTAAKPAASITSKPATLTTTSATSKL 348
P S P P P T S+A+ ++ + A+ PA T+ P
Sbjct: 587 H-PSPSQGPQGAPYPFPPVPTVTTSSATLSTVIATVASSPAGYKTASP------------ 633
Query: 349 IHPDEDISLEERRAQLPKYQRNLPRPGQAPIGNPPVGPIGGMMPPQPGIPQQQGMRPPMP 408
P Y + P PG PP G PP G R P
Sbjct: 634 -------------PGPPPYGKRAPSPGAYKTATPPGYKPGS--PPSFRTGTPPGYRGTSP 678
Query: 409 PHGQYGGHHQGMPGYLPGAMPPYG-QGPPMVPPYQGGPPRPP 449
P G G G P PG +PP G G P +PP P P
Sbjct: 679 PAGP-GTFKPGSPTVGPGPLPPAGPSGLPSLPPPPAAPASGP 719
Score = 55.8 bits (133), Expect = 8e-08
Identities = 80/303 (26%), Positives = 107/303 (35%), Gaps = 51/303 (16%)
Query: 157 PPGIPPL-----MPGV------PPLMPGMPPVM-PGMPPGLHHQRKYTQSFCGENIMMPM 204
PPG PP PG P PG PP G PPG + T G P
Sbjct: 633 PPGPPPYGKRAPSPGAYKTATPPGYKPGSPPSFRTGTPPGY----RGTSPPAGPGTFKPG 688
Query: 205 GGMMPPGPGIPPLMP-GMPPGMPPPVPRPGIPPMTQAQAVSAPGILNRPPAPTATVPAPQ 263
+ PGP +PP P G+P PPP PP+ SA I P T +P
Sbjct: 689 SPTVGPGP-LPPAGPSGLPSLPPPPAAPASGPPL------SATQIKQEPAEEYETPESPV 741
Query: 264 PPVTKPLFPSAGQAQAAVQGPVGTDFKPLNSTPATTTEPPKPTFPAYTQSTASTTSTTNS 323
PP P P P D S A + F + +S S
Sbjct: 742 PPARSPSPP-----------PKVVDVPSHASQSARFNKHLDRGFNSCARSDLYFVPLEGS 790
Query: 324 TAAKPAASITSKPATLTTTSA-TSKLIHPDEDISLEERRAQLPKYQRN--LPRPGQAPIG 380
AK A + K A K + + E R + + +R+ L + G+AP+
Sbjct: 791 KLAKKRADLVEKVRREAEQRAREEKEREREREREKEREREKERELERSVKLAQEGRAPVE 850
Query: 381 NPPVGPIGGMMPPQPG-----IPQQQGM-RPPMPPHGQYGGHHQGMPG------YLP-GA 427
P +GP+ P +PG +P G P + +Y H PG Y+P GA
Sbjct: 851 CPSLGPVPHRPPFEPGSAVATVPPYLGPDTPALRTLSEYARPHVMSPGNRNHPFYVPLGA 910
Query: 428 MPP 430
+ P
Sbjct: 911 VDP 913
Score = 49.7 bits (117), Expect = 6e-06
Identities = 62/251 (24%), Positives = 80/251 (31%), Gaps = 50/251 (19%)
Query: 216 PLMPGMPPGMPPPVPRP--GIPPMTQAQAVSAPGI--------LNRPPAPTATVPAPQPP 265
P P PP + PP P+P P +A P + + P + P PP
Sbjct: 155 PARPYHPPPLFPPSPQPPDSTPRQPEASFEPHPSVTPTGYHAPMEPPTSRMFQAPPGAPP 214
Query: 266 VTKPLFP--SAGQAQAAVQGPVGTDFKPLNSTPATTTEPPKPTFPAYTQSTASTTSTTNS 323
L+P + G GP G P + P PT P + S++ +
Sbjct: 215 PHPQLYPGGTGGVLSGPPMGPKGGGAASSVGGPNGGKQHPPPTTPI-------SVSSSGA 267
Query: 324 TAAKPAASITSKPATLTTTSATSKLIHPDEDISLEERRAQLPKYQRNL-PRPGQAPIGNP 382
+ A P +KP T P A P NL P P P+ N
Sbjct: 268 SGAPP-----TKPPTTPVGGGNLPSAPPP---------ANFPHVTPNLPPPPALRPLNNA 313
Query: 383 PVGPIGGMMPPQPG-IPQQQGMRPPMPPHGQYGGHHQGMPGYLPGAM--PPYGQGPPMVP 439
P G P PG +P M QGM G PG P P +P
Sbjct: 314 SASPPGLGAQPLPGHLPSPHAM-------------GQGMGGLPPGPEKGPTLAPSPHSLP 360
Query: 440 PYQGGPPRPPM 450
P P PPM
Sbjct: 361 PASSSAPAPPM 371
Score = 34.3 bits (77), Expect = 0.25
Identities = 46/220 (20%), Positives = 83/220 (37%), Gaps = 63/220 (28%)
Query: 90 MDERRRLLEQKTQESQKKKQQDDSDEYDDDDSAASTSFQPQPVQPQQGYIPPMAQPGLPP 149
+++ RR EQ+ +E ++++++ + ++ + + + V+ Q P+ P L P
Sbjct: 800 VEKVRREAEQRAREEKEREREREREKEREREKERELE---RSVKLAQEGRAPVECPSLGP 856
Query: 150 VPGAPGMPPG-----IPPLM-PGVPPLM----------------------------PGM- 174
VP P PG +PP + P P L PG+
Sbjct: 857 VPHRPPFEPGSAVATVPPYLGPDTPALRTLSEYARPHVMSPGNRNHPFYVPLGAVDPGLL 916
Query: 175 ----PPVMPGMPPGLHHQRKYTQSFCGENI----------MMPMGGMMPPGPGIPP---- 216
P + P +R+ + + + + P+ G+ PGPG+ P
Sbjct: 917 GYNVPALYSSDPAAREREREARERDLRDRLKPGFEVKPSELEPLHGV--PGPGLDPFPRH 974
Query: 217 ----LMPGMPPGMPPPVPRPGIPPMTQAQAVSAPGILNRP 252
L PG PPG+ P P + P+ + + A G RP
Sbjct: 975 GGLALQPG-PPGLHPFPFHPSLGPLERERLALAAGPALRP 1013
Score = 30.8 bits (68), Expect = 2.7
Identities = 15/42 (35%), Positives = 19/42 (45%)
Query: 122 AASTSFQPQPVQPQQGYIPPMAQPGLPPVPGAPGMPPGIPPL 163
A +F+P G +PP GLP +P P P PPL
Sbjct: 680 AGPGTFKPGSPTVGPGPLPPAGPSGLPSLPPPPAAPASGPPL 721
>gi|15890086 type IV collagen alpha 5 isoform 2 precursor [Homo
sapiens]
Length = 1691
Score = 73.6 bits (179), Expect = 4e-13
Identities = 100/388 (25%), Positives = 130/388 (33%), Gaps = 78/388 (20%)
Query: 129 PQPVQPQQGYIPPMAQPGLPPVPGAPGMP-----PGIPPLMPGVP--------PLMPGMP 175
P P P+ G P PG P PG PGMP PG P +PG P PG P
Sbjct: 83 PGPPGPK-GIRGPPGLPGFPGTPGLPGMPGHDGAPG-PQGIPGCNGTKGERGFPGSPGFP 140
Query: 176 PVM-PGMPPGLHHQRKYTQSFCGENIMMPMGGMMPPGP----------GIP-PLMPGMPP 223
+ P PPG+ + S ++ P G PGP GIP P+ P PP
Sbjct: 141 GLQGPPGPPGIPGMKGEPGSIIMSSLPGPKGNPGYPGPPGIQGLPGPTGIPGPIGPPGPP 200
Query: 224 GMPPPVPRPGIPPMTQAQAVSAPGI--------LNRPPAPTATV---------------- 259
G+ P PG+P ++ G L PP P +
Sbjct: 201 GLMGPPGPPGLPGPKGNMGLNFQGPKGEKGEQGLQGPPGPPGQISEQKRPIDVEFQKGDQ 260
Query: 260 -------PAPQPPVTKPLFPSAGQ-AQAAVQGPVGTDFKP----LNSTPATTTEPPKPTF 307
P P + P P G+ + QG G KP N P P P +
Sbjct: 261 GLPGDRGPPGPPGIRGPPGPPGGEKGEKGEQGEPGKRGKPGKDGENGQPGIPGLPGDPGY 320
Query: 308 PAYTQSTASTTSTTNSTAAKPAASITSKPATLTTTSATSKLIHPDEDISLEERRAQLPKY 367
P ++ P + +P T T + P ER +
Sbjct: 321 PGEPGRDGEKGQKGDTGPPGPPGLVIPRPGTGITIGEKGNIGLPGLPGEKGERGFPGIQG 380
Query: 368 QRNLPRPGQAPIGNPPVGPIGGMMPPQPGIPQQQGMRPPMPPHGQYGGHHQGMPGY--LP 425
LP P A + PP GP PG P ++G + P G G+ G P
Sbjct: 381 PPGLPGPPGAAVMGPP-GP--------PGFPGERGQKGDEGPPGISIPGPPGLDGQPGAP 431
Query: 426 GAMPPYGQGPPMVPP----YQGGPPRPP 449
G P G P +PP + GPP PP
Sbjct: 432 GLPGPPGPAGPHIPPSDEICEPGPPGPP 459
Score = 68.2 bits (165), Expect = 2e-11
Identities = 104/375 (27%), Positives = 127/375 (33%), Gaps = 96/375 (25%)
Query: 141 PMAQPGLPPVPGAPGMPPGI----PPLMPGVP----------PLMPGMPPVMPGMPPGLH 186
P PG+P PGAPG P I PP PG P P PG PP +PG L
Sbjct: 714 PKGFPGIPGPPGAPGTPGRIGLEGPPGPPGFPGPKGEPGFALPGPPG-PPGLPGFKGALG 772
Query: 187 HQRKYTQSFCG----------ENIMMPMGGMMP---PGPGIPPLMPGM-------PPGMP 226
K + F G + + P G + P PGP PP +PG+ PPG+P
Sbjct: 773 P--KGDRGFPGPPGPPGRTGLDGLPGPKGDVGPNGQPGPMGPPGLPGIGVQGPPGPPGIP 830
Query: 227 PPVPRPGIPPMTQAQAVSAPGILNRPPAPTATVPAPQPPVTKPLFPSAGQAQAAVQGPVG 286
P+ +PG+ PG P P VP P P P A GP+G
Sbjct: 831 GPIGQPGLH--------GIPGEKGDPGPPGLDVPGPPGERGSPGIPGA-------PGPIG 875
Query: 287 TDFKP-------LNSTPATTTE-----PPKPTFPA---------------YTQSTASTTS 319
P + P T E PP P P Q
Sbjct: 876 PPGSPGLPGKAGASGFPGTKGEMGMMGPPGPPGPLGIPGRSGVPGLKGDDGLQGQPGLPG 935
Query: 320 TTNSTAAKPAASITSKPATLTTTSATSKLIHPDEDISLEERRAQLPKYQRNLP-RPGQAP 378
T +K + P + SK + + PK + LP PGQ
Sbjct: 936 PTGEKGSKGEPGLPGPPGPMDPNLLGSKGEKGEPGLP-GIPGVSGPKGYQGLPGDPGQPG 994
Query: 379 I-GNP----PVGPIGGMMPPQPGIPQQQGMRPPMPPHGQYGGHHQGMPGYLPGAMPPYGQ 433
+ G P P GP G PG+P Q G+ P G G G PG PP
Sbjct: 995 LSGQPGLPGPPGPKG-----NPGLPGQPGLIGPPGLKGTIG--DMGFPGPQGVEGPP--- 1044
Query: 434 GPPMVPPYQGGPPRP 448
GP VP G P P
Sbjct: 1045 GPSGVPGQPGSPGLP 1059
Score = 66.2 bits (160), Expect = 6e-11
Identities = 92/320 (28%), Positives = 119/320 (37%), Gaps = 48/320 (15%)
Query: 145 PGLPPVPGAPGMPPGIP-PLMPGVPPLMPGMPPVMPGMPPGLHHQRKYTQSFCGENIMMP 203
PG P PG G PG+P P P P +PG P ++ PPGL K T G P
Sbjct: 987 PGDPGQPGLSGQ-PGLPGPPGPKGNPGLPGQPGLIG--PPGL----KGTIGDMG--FPGP 1037
Query: 204 MGGMMPPGPGIPPLMPGMP--PGMPPPVPRPGIPPMTQAQAVSAPGILNRPPAPTATVPA 261
G PPGP P PG P PG PGI ++ PG+ P
Sbjct: 1038 QGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGI------SSIGLPGL-----------PG 1080
Query: 262 PQPPVTKPLFPSAGQAQAAVQGPVGTDFKP-LNSTPATTTEPPKPTFPAYTQSTASTTST 320
P+ P +P ++G VG P L TP +P P FP T
Sbjct: 1081 PKGEPGLPGYP----GNPGIKGSVGDPGLPGLPGTPGAKGQPGLPGFP----GTPGPPGP 1132
Query: 321 TNSTAAKPAASITSKPATLTTTSATSKLIHPDEDISLEERRAQLPKYQRNLPRPGQAPIG 380
+ + +P + + P E + P Q+ PGQ G
Sbjct: 1133 KGISGPPGNPGLPGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGPAGQKG--EPGQPGFG 1190
Query: 381 NPPVGPIGGMMPPQ-----PGIPQQQGMRPPMPPHGQYG-GHHQGMPGYLPGAMPPYGQG 434
NP + G+ + PGIP G+ P G +G QG PG PG+ P +G
Sbjct: 1191 NPGPPGLPGLSGQKGDGGLPGIPGNPGLPGPKGEPGFHGFPGVQGPPG-PPGSPGPALEG 1249
Query: 435 PPMVPPYQGGPPRP-PMGMR 453
P P QG P RP P G +
Sbjct: 1250 PKGNPGPQGPPGRPGPTGFQ 1269
Score = 64.3 bits (155), Expect = 2e-10
Identities = 105/367 (28%), Positives = 128/367 (34%), Gaps = 85/367 (23%)
Query: 144 QPGLPPVPGAPGMPPGI-----PPLMPGVP----PLMPGMPPVMPGMPPGLHHQRKYTQS 194
QPGLP PG PG PPG PP PG+P P+ G P PG PPG + K Q
Sbjct: 1117 QPGLPGFPGTPG-PPGPKGISGPPGNPGLPGEPGPVGGGGHPGQPG-PPG--EKGKPGQ- 1171
Query: 195 FCGENIMMPMGGMMPPG---------PGIPPL--------MPGMP--PGMPPPVPRPGIP 235
+ I P G PG PG+P L +PG+P PG+P P PG
Sbjct: 1172 ---DGIPGPAGQKGEPGQPGFGNPGPPGLPGLSGQKGDGGLPGIPGNPGLPGPKGEPGFH 1228
Query: 236 PMTQAQAVSAPGILNRPPAPTATV------PAPQPPVTKPLFPSAGQAQAAVQGPVGT-- 287
Q P P +P + P PQ P +P P+ Q +GP G
Sbjct: 1229 GFPGVQGPPGP-----PGSPGPALEGPKGNPGPQGPPGRP-GPTGFQGLPGPEGPPGLPG 1282
Query: 288 --DFKPLNSTPATTTEPPKPTF-----PAYTQSTASTTSTTNSTAAKPAASITSKPATLT 340
K P P P P Q + P +
Sbjct: 1283 NGGIKGEKGNPGQPGLPGLPGLKGDQGPPGLQGNPGRPGLNGMKGDPGLPGVPGFPG-MK 1341
Query: 341 TTSATSKLIHPDEDISLEERRAQLPKYQRNLPRP-GQAPIGNPPVGPIGGMMPPQPGI-- 397
S P+ + L P LP P GQ+ I GP G +P QPG+
Sbjct: 1342 GPSGVPGSAGPEGEPGLIG-----PPGPPGLPGPSGQSIIIKGDAGPPG--IPGQPGLKG 1394
Query: 398 ---PQ-QQGMRPPMPPHGQYGGHHQGMPGY-----------LPGAMPPYGQGPPMVPPYQ 442
PQ QG+ P P G G G+PG+ LPG G P P
Sbjct: 1395 LPGPQGPQGLPGPTGPPGDPG--RNGLPGFDGAGGRKGDPGLPGQPGTRGLDGPPGPDGL 1452
Query: 443 GGPPRPP 449
GPP PP
Sbjct: 1453 QGPPGPP 1459
Score = 58.9 bits (141), Expect = 9e-09
Identities = 100/380 (26%), Positives = 121/380 (31%), Gaps = 115/380 (30%)
Query: 135 QQGYIPPMAQPGLPPVPGAPGMP-----PGIPPLMPGV--------PPLMPGMPPVMPGM 181
Q G P PG+P PGAPG P PG PG+ P PG+P +PG
Sbjct: 519 QAGATGPKGLPGIPGAPGAPGFPGSKGEPGDILTFPGMKGDKGELGSPGAPGLPG-LPGT 577
Query: 182 P-----PGLHHQRKYTQSFCGENIMMPMGGMMPPGPGIPPLMPGMP--PGMPPPVPRPGI 234
P PGL + GE GG+ G PP PG+P PG P+ PG
Sbjct: 578 PGQDGLPGLPGPK-------GE-----PGGITFKGERGPPGNPGLPGLPGNIGPMGPPGF 625
Query: 235 PPMTQAQAVSAPGILNRPPAPTATVPAPQP--PVTKPLFPSAGQAQAAVQGPVGTDFKPL 292
P G+ P P P P +T+P P G VG L
Sbjct: 626 GPPGPVGEKGIQGVAGNPGQPGIPGPKGDPGQTITQPGKPGL-PGNPGRDGDVG-----L 679
Query: 293 NSTPATTTEPPKPTFPAYTQSTASTTSTTNSTAAKPAASITSKPATLTTTSATSKLIHPD 352
P +P P P + P + P
Sbjct: 680 PGDPGLPGQPGLPGIPG-----------SKGEPGIPGIGLPGPPG--------------- 713
Query: 353 EDISLEERRAQLPKYQRNLPRPGQAPIGNP----------------PVGPIGGMMPPQPG 396
PK +P P AP G P P G G +P PG
Sbjct: 714 ------------PKGFPGIPGPPGAP-GTPGRIGLEGPPGPPGFPGPKGEPGFALPGPPG 760
Query: 397 IPQQQGMRPPMPPHGQYGGHHQGMPG--------YLPGA---MPPYGQGPPMVPP----- 440
P G + + P G G G PG LPG + P GQ PM PP
Sbjct: 761 PPGLPGFKGALGPKGDRG--FPGPPGPPGRTGLDGLPGPKGDVGPNGQPGPMGPPGLPGI 818
Query: 441 YQGGPPRPPMGMRPPVMSQG 460
GPP PP G+ P+ G
Sbjct: 819 GVQGPPGPP-GIPGPIGQPG 837
Score = 58.5 bits (140), Expect = 1e-08
Identities = 97/344 (28%), Positives = 125/344 (36%), Gaps = 60/344 (17%)
Query: 136 QGYIPPMAQPGLPPVPGAPGMPPGIPPL-MPGV--PPLMPGM----PPVMPGMP-----P 183
+G+ P PG + G PG + P PG PP +PG+ PP PG+P P
Sbjct: 777 RGFPGPPGPPGRTGLDGLPGPKGDVGPNGQPGPMGPPGLPGIGVQGPPGPPGIPGPIGQP 836
Query: 184 GLHHQRKYTQSFCGENIMMPMGGMMPPGPGIPPLMPGMPPGMPPPVPRPGIPPMT-QAQA 242
GLH GE G+ PGP PG+ PG P P+ PG P + +A A
Sbjct: 837 GLH-------GIPGEKGDPGPPGLDVPGPPGERGSPGI-PGAPGPIGPPGSPGLPGKAGA 888
Query: 243 VSAPGI-----LNRPPAPTATVPAPQPPVTKPLFPSAG-QAQAAVQGPVGTDFKPLNSTP 296
PG + PP P + P L G Q Q + GP G K P
Sbjct: 889 SGFPGTKGEMGMMGPPGPPGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGE--KGSKGEP 946
Query: 297 ATTTEPPKPTFPAYTQSTASTTSTTNSTAAKPAASITSKPATLTTTSATSKLIHPDE-DI 355
PP P P + S K + P P + +
Sbjct: 947 G-LPGPPGPMDP----------NLLGSKGEKGEPGLPGIPGVSGPKGYQGLPGDPGQPGL 995
Query: 356 SLEERRAQLPKYQRNLPRPGQAPIGNPP-----------VGPIGGMMPPQP-GIPQQQGM 403
S + P + N PGQ + PP GP G PP P G+P Q G
Sbjct: 996 SGQPGLPGPPGPKGNPGLPGQPGLIGPPGLKGTIGDMGFPGPQGVEGPPGPSGVPGQPG- 1054
Query: 404 RPPMPPHGQYGGHHQGMPGYLPGAMP--PYGQGPPMVPPYQGGP 445
P +P GQ G +G PG +P P +G P +P Y G P
Sbjct: 1055 SPGLP--GQKG--DKGDPGISSIGLPGLPGPKGEPGLPGYPGNP 1094
Score = 56.2 bits (134), Expect = 6e-08
Identities = 96/361 (26%), Positives = 124/361 (34%), Gaps = 51/361 (14%)
Query: 135 QQGYIPPMAQPGLPPVPGAPGMPPGIPPLMPGVPPLM--PGMPPVMPGMPPGLHHQRKYT 192
++G+ PGLP PGA M P PP PG G P + PPGL Q
Sbjct: 372 ERGFPGIQGPPGLPGPPGAAVMGPPGPPGFPGERGQKGDEGPPGISIPGPPGLDGQPG-- 429
Query: 193 QSFCGENIMMPMGGMMPPGPGIPPLMPGMPPGMPPPVPRPGIPPMTQAQAVS-------- 244
+ P G P GP IPP PG P P PG + Q V
Sbjct: 430 ----APGLPGPPG---PAGPHIPPSDEICEPGPPGPPGSPGDKGLQGEQGVKGDKGDTCF 482
Query: 245 ---APGILNRPPAPTATVPAPQPPVTKPLFPSAGQ-AQAAVQGPVGTDFKPLNSTPATTT 300
GI + PP P PP + G+ QA GP G P P
Sbjct: 483 NCIGTGI-SGPPGQPGLPGLPGPPGSLGFPGQKGEKGQAGATGPKGLPGIP--GAPGAPG 539
Query: 301 EPPKPTFPAYTQSTASTTSTTNSTAAKPAASITSKPATLTTTSATSKLIHPDEDISLEER 360
P P + + A + P T E + +
Sbjct: 540 FPGSKGEPGDILTFPGMKGDKGELGSPGAPGLPGLPGTPGQDGLPGLPGPKGEPGGITFK 599
Query: 361 RAQLPKYQRNLP-RPGQ-APIGNP---PVGPIG--GMM-----PPQPGIPQQQG------ 402
+ P LP PG P+G P P GP+G G+ P QPGIP +G
Sbjct: 600 GERGPPGNPGLPGLPGNIGPMGPPGFGPPGPVGEKGIQGVAGNPGQPGIPGPKGDPGQTI 659
Query: 403 ---MRPPMPPHGQYGGHHQGMPGYLPGAMPPYGQGPPMVPPYQGGPPRPPMGMRPPVMSQ 459
+P +P + G G+PG PG P G P +P +G P P +G+ P +
Sbjct: 660 TQPGKPGLPGNPGRDG-DVGLPGD-PGL--PGQPGLPGIPGSKGEPGIPGIGLPGPPGPK 715
Query: 460 G 460
G
Sbjct: 716 G 716
Score = 55.5 bits (132), Expect = 1e-07
Identities = 106/402 (26%), Positives = 136/402 (33%), Gaps = 130/402 (32%)
Query: 129 PQPVQPQQGYIPP---MAQPGLPPVPGAPG---------------------------MPP 158
P P P +IPP + +PG P PG+PG PP
Sbjct: 434 PGPPGPAGPHIPPSDEICEPGPPGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGPP 493
Query: 159 GIP--PLMPGVPPLM--PGM-----------PPVMPGMP--------PGLHHQRKYTQSF 195
G P P +PG P + PG P +PG+P PG + +F
Sbjct: 494 GQPGLPGLPGPPGSLGFPGQKGEKGQAGATGPKGLPGIPGAPGAPGFPGSKGEPGDILTF 553
Query: 196 CGENIMMPMGGMMPPG-PGIPPLMPGMP-----PGMPPPVPRPGIPPMTQAQAVSAPGIL 249
G + G + PG PG+P L PG P PG+P P PG +T PG
Sbjct: 554 PG--MKGDKGELGSPGAPGLPGL-PGTPGQDGLPGLPGPKGEPG--GITFKGERGPPGNP 608
Query: 250 NRPPAPTATVPAPQPPVTKPLFPSAGQAQAAVQGPVGTDFKPLNSTP-----ATTTEPPK 304
P P P P P + +QG G +P P T T+P K
Sbjct: 609 GLPGLPGNIGPMGPP----GFGPPGPVGEKGIQGVAGNPGQPGIPGPKGDPGQTITQPGK 664
Query: 305 PTFPAYTQSTASTTSTTNSTAAKPAASITSKPATLTTTSATSKLIHPDEDISLEERRAQL 364
P P + +P L
Sbjct: 665 PGLP-------GNPGRDGDVGLPGDPGLPGQPG--------------------------L 691
Query: 365 PKYQRNLPRPGQAPIGNP-PVGPIG--GM--MPPQPGIPQQQGMRPPMPPHGQYGGHHQG 419
P + PG IG P P GP G G+ P PG P + G+ P P G G +G
Sbjct: 692 PGIPGSKGEPGIPGIGLPGPPGPKGFPGIPGPPGAPGTPGRIGLEGPPGPPGFPG--PKG 749
Query: 420 MPGY-LPGAMPPYGQGPPMVPPYQG-----------GPPRPP 449
PG+ LPG PP GPP +P ++G GPP PP
Sbjct: 750 EPGFALPG--PP---GPPGLPGFKGALGPKGDRGFPGPPGPP 786
Score = 54.7 bits (130), Expect = 2e-07
Identities = 94/339 (27%), Positives = 123/339 (36%), Gaps = 71/339 (20%)
Query: 136 QGYIPPMAQPGLPPVPGAPGMP--------PGIPPL-MPGVPPLMPGMPPVMPGMP--PG 184
QG P G+P PG+PG+P PGI + +PG+P P P +PG P PG
Sbjct: 1038 QGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGISSIGLPGLPG--PKGEPGLPGYPGNPG 1095
Query: 185 LHHQRKYTQSFCGENIMMPMGGMMPPGPGIPPLMPGMPPGMPPPVPRPGIPPMTQAQAVS 244
+ G + PG +PG+ PG P +PG+P
Sbjct: 1096 I------------------KGSVGDPG------LPGL-PGTPGAKGQPGLPGFP-----G 1125
Query: 245 APGILNRPPAPTA-TVPAPQPPVTKPLFPSAGQAQAAVQGPVGTDFKP-LNSTPATTTEP 302
PG PP P + P P + P G GP G KP + P +
Sbjct: 1126 TPG----PPGPKGISGPPGNPGLPGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGPAGQK 1181
Query: 303 PKPTFPAYTQSTASTTSTTNSTAAKPAASITSKPATLTTTSATSKLIHPDEDISLEE-RR 361
+P P + P S L L P +
Sbjct: 1182 GEPGQPGFGNP---------GPPGLPGLSGQKGDGGLPGIPGNPGLPGPKGEPGFHGFPG 1232
Query: 362 AQLPKYQRNLPRPG-QAPIGNP-PVGPIGGMMPPQ-PGIPQQQGMRPPMPPHGQYGGH-- 416
Q P P P + P GNP P GP G P G+P +G P +P +G G
Sbjct: 1233 VQGPPGPPGSPGPALEGPKGNPGPQGPPGRPGPTGFQGLPGPEG-PPGLPGNGGIKGEKG 1291
Query: 417 HQGMPGYLPGAMPPYG-QGPPMVPPYQGGPPRPPM-GMR 453
+ G PG LPG G QGPP + QG P RP + GM+
Sbjct: 1292 NPGQPG-LPGLPGLKGDQGPPGL---QGNPGRPGLNGMK 1326
Score = 52.4 bits (124), Expect = 9e-07
Identities = 104/382 (27%), Positives = 130/382 (34%), Gaps = 86/382 (22%)
Query: 141 PMAQPGLPPVPGAPGMPPGIPPL-MPGVP-----PLMPGMP-PVMPGMPPGLHHQRKYTQ 193
P+ QPGL +PG G PG P L +PG P P +PG P P+ P PGL + +
Sbjct: 832 PIGQPGLHGIPGEKG-DPGPPGLDVPGPPGERGSPGIPGAPGPIGPPGSPGLPGKAGASG 890
Query: 194 SFCGENIMMPMGGMMPPGP-------GIPPL--------MPGMP-----------PGMP- 226
+ M MG PPGP G+P L PG+P PG+P
Sbjct: 891 FPGTKGEMGMMGPPGPPGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPG 950
Query: 227 PPVPR----------------PGIPPMTQAQAVSA-------PGI-----LNRPPAPTAT 258
PP P PGIP ++ + PG+ L PP P
Sbjct: 951 PPGPMDPNLLGSKGEKGEPGLPGIPGVSGPKGYQGLPGDPGQPGLSGQPGLPGPPGPKGN 1010
Query: 259 VPAP-QPPVTKPLFPSAGQAQAAVQGPVGTDFKPLNSTPATTTEPPKPTFPAYTQSTAST 317
P QP + P GP G + P + P +P P
Sbjct: 1011 PGLPGQPGLIGPPGLKGTIGDMGFPGPQGVE-----GPPGPSGVPGQPGSPGLPGQKGDK 1065
Query: 318 TSTTNSTAAKPAASITSKPATLTTTSATSKLIHPDEDISLEERRAQLPKYQRNLPRPGQA 377
S+ P L + D L LP +PG
Sbjct: 1066 GDPGISSIGLPGLPGPKGEPGLPGYPGNPGIKGSVGDPGLPG----LPGTPGAKGQPGLP 1121
Query: 378 PI-GNP-PVGPIGGMMPP-QPGIPQQQGMRPPMPPHGQYGGHHQGMPGYLPGAMPPYGQ- 433
G P P GP G PP PG+P + G P G GG H G PG PG GQ
Sbjct: 1122 GFPGTPGPPGPKGISGPPGNPGLPGEPG------PVG--GGGHPGQPG-PPGEKGKPGQD 1172
Query: 434 GPPMVPPYQGGPPRPPMGMRPP 455
G P +G P +P G P
Sbjct: 1173 GIPGPAGQKGEPGQPGFGNPGP 1194
Score = 50.8 bits (120), Expect = 3e-06
Identities = 99/357 (27%), Positives = 119/357 (33%), Gaps = 113/357 (31%)
Query: 129 PQPVQPQQGYIPPMAQPGLPPVPGAPGMPPGIPPLMPGVPPLMPGMP-----------PV 177
P PV ++G PG P +PG G PG PG P L PG P P
Sbjct: 628 PGPVG-EKGIQGVAGNPGQPGIPGPKG-DPGQTITQPGKPGL-PGNPGRDGDVGLPGDPG 684
Query: 178 MPGMP--PGLHHQRKYTQSFCGENIMMPMGGMMPPGPGIPPLMPGMPPGMPPPVPRPGI- 234
+PG P PG+ + GE + +G PPGP P +PG PPG P R G+
Sbjct: 685 LPGQPGLPGIPGSK-------GEPGIPGIGLPGPPGPKGFPGIPG-PPGAPGTPGRIGLE 736
Query: 235 -PPMTQAQAVSAPGILNRPPAPTATVPAPQPPVTKPLFPSAGQAQAAVQGPVGTDFKPLN 293
PP PG P +P P P P F A GP G P
Sbjct: 737 GPP-------GPPGFPGPKGEPGFALPGPPGPPGLPGFKGA-------LGPKGDRGFP-- 780
Query: 294 STPATTTEPPKPTFPAYTQSTASTTSTTNSTAAKPAASITSKPATLTTTSATSKLIHPDE 353
PP P T K +P
Sbjct: 781 -------GPPGP---------PGRTGLDGLPGPKGDVGPNGQPG---------------- 808
Query: 354 DISLEERRAQLPKYQRNLPRPG-QAPIGNPPV-GPIG--GM--MPPQPGIPQQQGMRPPM 407
P LP G Q P G P + GPIG G+ +P + G P G+ P
Sbjct: 809 -----------PMGPPGLPGIGVQGPPGPPGIPGPIGQPGLHGIPGEKGDPGPPGLDVPG 857
Query: 408 PPHGQYGGHHQGMPGYLPGAMPPYG-QGPPMVPPYQG--------------GPPRPP 449
PP +G PG +PGA P G G P +P G GPP PP
Sbjct: 858 PP------GERGSPG-IPGAPGPIGPPGSPGLPGKAGASGFPGTKGEMGMMGPPGPP 907
Score = 50.8 bits (120), Expect = 3e-06
Identities = 57/172 (33%), Positives = 68/172 (39%), Gaps = 43/172 (25%)
Query: 145 PGLPPVPGAPGM--PPGIPPLMPGVPPLMPGM--PPVMPGMPPGLHHQRKYTQSFCGENI 200
PGLP VPG PGM P G+P P PG+ PP PG+P G++I
Sbjct: 1329 PGLPGVPGFPGMKGPSGVPG--SAGPEGEPGLIGPPGPPGLP-----------GPSGQSI 1375
Query: 201 MMPMGGMMPPG-PGIPPL--MPGM--PPGMPPPVPRPGIPPMTQAQAVSA-------PGI 248
++ G PPG PG P L +PG P G+P P PG P PG+
Sbjct: 1376 II-KGDAGPPGIPGQPGLKGLPGPQGPQGLPGPTGPPGDPGRNGLPGFDGAGGRKGDPGL 1434
Query: 249 --------LNRPPAPTATVPAPQPPVTKP-----LFPSAGQAQAAVQGPVGT 287
L+ PP P P PP T L Q A Q P GT
Sbjct: 1435 PGQPGTRGLDGPPGPDGLQGPPGPPGTSSVAHGFLITRHSQTTDAPQCPQGT 1486
Score = 36.2 bits (82), Expect = 0.065
Identities = 37/121 (30%), Positives = 45/121 (37%), Gaps = 39/121 (32%)
Query: 369 RNLPRPGQAPIGNPPVGPIGGMMPP-QPGIPQ-----------------QQGMRPPMPPH 410
+ LP P P P GP G M PP PG+P +QG++ P P
Sbjct: 182 QGLPGPTGIPGPIGPPGPPGLMGPPGPPGLPGPKGNMGLNFQGPKGEKGEQGLQGPPGPP 241
Query: 411 GQYGGHH-----------QGMPGYLPGAMPPYGQGPPMVPPYQGGPPRPPMGMRPPVMSQ 459
GQ QG+PG +GPP PP GPP PP G + Q
Sbjct: 242 GQISEQKRPIDVEFQKGDQGLPG---------DRGPPG-PPGIRGPPGPPGGEKGEKGEQ 291
Query: 460 G 460
G
Sbjct: 292 G 292
Score = 35.0 bits (79), Expect = 0.14
Identities = 38/98 (38%), Positives = 40/98 (40%), Gaps = 21/98 (21%)
Query: 372 PRPGQAPIGNPPVGPIGGMMPPQPGIPQQQGMRPPMPP-----HGQYGG-------HHQG 419
P P P N G G P PG P QG PP PP G+ G +G
Sbjct: 116 PGPQGIPGCNGTKGERG--FPGSPGFPGLQG--PPGPPGIPGMKGEPGSIIMSSLPGPKG 171
Query: 420 MPGYLPGAMPPYGQGPPMVPPYQG--GPPRPPMGMRPP 455
PGY PG PP QG P G GPP PP M PP
Sbjct: 172 NPGY-PG--PPGIQGLPGPTGIPGPIGPPGPPGLMGPP 206
Score = 33.9 bits (76), Expect = 0.32
Identities = 23/56 (41%), Positives = 28/56 (50%), Gaps = 5/56 (8%)
Query: 395 PGIPQQQGMRPPMPPHGQYGGHHQGMPGYLPGAMPPYGQGPPMVPPYQGGPPRPPM 450
PG+P G P P GQ G G+PG PG P +GPP +P + G P P M
Sbjct: 59 PGLPGFPGPEGPPGPRGQKG--DDGIPG-PPG--PKGIRGPPGLPGFPGTPGLPGM 109
>gi|4502955 type IV collagen alpha 5 isoform 1 precursor [Homo
sapiens]
Length = 1685
Score = 73.6 bits (179), Expect = 4e-13
Identities = 100/388 (25%), Positives = 130/388 (33%), Gaps = 78/388 (20%)
Query: 129 PQPVQPQQGYIPPMAQPGLPPVPGAPGMP-----PGIPPLMPGVP--------PLMPGMP 175
P P P+ G P PG P PG PGMP PG P +PG P PG P
Sbjct: 83 PGPPGPK-GIRGPPGLPGFPGTPGLPGMPGHDGAPG-PQGIPGCNGTKGERGFPGSPGFP 140
Query: 176 PVM-PGMPPGLHHQRKYTQSFCGENIMMPMGGMMPPGP----------GIP-PLMPGMPP 223
+ P PPG+ + S ++ P G PGP GIP P+ P PP
Sbjct: 141 GLQGPPGPPGIPGMKGEPGSIIMSSLPGPKGNPGYPGPPGIQGLPGPTGIPGPIGPPGPP 200
Query: 224 GMPPPVPRPGIPPMTQAQAVSAPGI--------LNRPPAPTATV---------------- 259
G+ P PG+P ++ G L PP P +
Sbjct: 201 GLMGPPGPPGLPGPKGNMGLNFQGPKGEKGEQGLQGPPGPPGQISEQKRPIDVEFQKGDQ 260
Query: 260 -------PAPQPPVTKPLFPSAGQ-AQAAVQGPVGTDFKP----LNSTPATTTEPPKPTF 307
P P + P P G+ + QG G KP N P P P +
Sbjct: 261 GLPGDRGPPGPPGIRGPPGPPGGEKGEKGEQGEPGKRGKPGKDGENGQPGIPGLPGDPGY 320
Query: 308 PAYTQSTASTTSTTNSTAAKPAASITSKPATLTTTSATSKLIHPDEDISLEERRAQLPKY 367
P ++ P + +P T T + P ER +
Sbjct: 321 PGEPGRDGEKGQKGDTGPPGPPGLVIPRPGTGITIGEKGNIGLPGLPGEKGERGFPGIQG 380
Query: 368 QRNLPRPGQAPIGNPPVGPIGGMMPPQPGIPQQQGMRPPMPPHGQYGGHHQGMPGY--LP 425
LP P A + PP GP PG P ++G + P G G+ G P
Sbjct: 381 PPGLPGPPGAAVMGPP-GP--------PGFPGERGQKGDEGPPGISIPGPPGLDGQPGAP 431
Query: 426 GAMPPYGQGPPMVPP----YQGGPPRPP 449
G P G P +PP + GPP PP
Sbjct: 432 GLPGPPGPAGPHIPPSDEICEPGPPGPP 459
Score = 68.2 bits (165), Expect = 2e-11
Identities = 104/375 (27%), Positives = 127/375 (33%), Gaps = 96/375 (25%)
Query: 141 PMAQPGLPPVPGAPGMPPGI----PPLMPGVP----------PLMPGMPPVMPGMPPGLH 186
P PG+P PGAPG P I PP PG P P PG PP +PG L
Sbjct: 714 PKGFPGIPGPPGAPGTPGRIGLEGPPGPPGFPGPKGEPGFALPGPPG-PPGLPGFKGAL- 771
Query: 187 HQRKYTQSFCG----------ENIMMPMGGMMP---PGPGIPPLMPGM-------PPGMP 226
K + F G + + P G + P PGP PP +PG+ PPG+P
Sbjct: 772 -GPKGDRGFPGPPGPPGRTGLDGLPGPKGDVGPNGQPGPMGPPGLPGIGVQGPPGPPGIP 830
Query: 227 PPVPRPGIPPMTQAQAVSAPGILNRPPAPTATVPAPQPPVTKPLFPSAGQAQAAVQGPVG 286
P+ +PG+ PG P P VP P P P A GP+G
Sbjct: 831 GPIGQPGLH--------GIPGEKGDPGPPGLDVPGPPGERGSPGIPGA-------PGPIG 875
Query: 287 TDFKP-------LNSTPATTTE-----PPKPTFPA---------------YTQSTASTTS 319
P + P T E PP P P Q
Sbjct: 876 PPGSPGLPGKAGASGFPGTKGEMGMMGPPGPPGPLGIPGRSGVPGLKGDDGLQGQPGLPG 935
Query: 320 TTNSTAAKPAASITSKPATLTTTSATSKLIHPDEDISLEERRAQLPKYQRNLP-RPGQAP 378
T +K + P + SK + + PK + LP PGQ
Sbjct: 936 PTGEKGSKGEPGLPGPPGPMDPNLLGSKGEKGEPGLP-GIPGVSGPKGYQGLPGDPGQPG 994
Query: 379 I-GNP----PVGPIGGMMPPQPGIPQQQGMRPPMPPHGQYGGHHQGMPGYLPGAMPPYGQ 433
+ G P P GP G PG+P Q G+ P G G G PG PP
Sbjct: 995 LSGQPGLPGPPGPKG-----NPGLPGQPGLIGPPGLKGTIG--DMGFPGPQGVEGPP--- 1044
Query: 434 GPPMVPPYQGGPPRP 448
GP VP G P P
Sbjct: 1045 GPSGVPGQPGSPGLP 1059
Score = 66.2 bits (160), Expect = 6e-11
Identities = 94/329 (28%), Positives = 121/329 (36%), Gaps = 49/329 (14%)
Query: 145 PGLPPVPGAPGMPPGIP-PLMPGVPPLMPGMPPVMPGMPPGLHHQRKYTQSFCGENIMMP 203
PG P PG G PG+P P P P +PG P ++ PPGL K T G P
Sbjct: 987 PGDPGQPGLSGQ-PGLPGPPGPKGNPGLPGQPGLIG--PPGL----KGTIGDMG--FPGP 1037
Query: 204 MGGMMPPGPGIPPLMPGMP--PGMPPPVPRPGIPPMTQAQAVSAPGILNRPPAPTATVPA 261
G PPGP P PG P PG PGI ++ PG+ P
Sbjct: 1038 QGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGI------SSIGLPGL-----------PG 1080
Query: 262 PQPPVTKPLFPSAGQAQAAVQGPVGTDFKP-LNSTPATTTEPPKPTFPAYTQSTASTTST 320
P+ P +P ++G VG P L TP +P P FP T
Sbjct: 1081 PKGEPGLPGYP----GNPGIKGSVGDPGLPGLPGTPGAKGQPGLPGFP----GTPGPPGP 1132
Query: 321 TNSTAAKPAASITSKPATLTTTSATSKLIHPDEDISLEERRAQLPKYQRNLPRPGQAPIG 380
+ + +P + + P E + P Q+ PGQ G
Sbjct: 1133 KGISGPPGNPGLPGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGPAGQKG--EPGQPGFG 1190
Query: 381 NPPVGPIGGMMPPQ-----PGIPQQQGMRPPMPPHGQYG-GHHQGMPGYLPGAMPPYGQG 434
NP + G+ + PGIP G+ P G +G QG PG PG+ P +G
Sbjct: 1191 NPGPPGLPGLSGQKGDGGLPGIPGNPGLPGPKGEPGFHGFPGVQGPPG-PPGSPGPALEG 1249
Query: 435 PPMVPPYQGGPPRP--PMGMRPPVMSQGG 461
P P QG P RP P PP + G
Sbjct: 1250 PKGNPGPQGPPGRPGLPGPEGPPGLPGNG 1278
Score = 65.1 bits (157), Expect = 1e-10
Identities = 103/363 (28%), Positives = 128/363 (35%), Gaps = 83/363 (22%)
Query: 144 QPGLPPVPGAPGMPPGI-----PPLMPGVP----PLMPGMPPVMPGMPPGLHHQRKYTQS 194
QPGLP PG PG PPG PP PG+P P+ G P PG PPG + K Q
Sbjct: 1117 QPGLPGFPGTPG-PPGPKGISGPPGNPGLPGEPGPVGGGGHPGQPG-PPG--EKGKPGQ- 1171
Query: 195 FCGENIMMPMGGMMPPG---------PGIPPL--------MPGMP--PGMPPPVPRPGIP 235
+ I P G PG PG+P L +PG+P PG+P P PG
Sbjct: 1172 ---DGIPGPAGQKGEPGQPGFGNPGPPGLPGLSGQKGDGGLPGIPGNPGLPGPKGEPGFH 1228
Query: 236 PMTQAQAVSAPGILNRPPAPTATVPAPQPPVTKPLFPSAGQAQAAVQGPVGTDFKP---- 291
PG+ P P + PA + P P P + + GP G P
Sbjct: 1229 --------GFPGVQGPPGPPGSPGPALEGPKGNP-GPQGPPGRPGLPGPEGPPGLPGNGG 1279
Query: 292 LNSTPATTTEPPKPTFPAYTQSTASTTSTTNS-----TAAKPAASITSKPA--TLTTTSA 344
+ +P P P N K + P + S
Sbjct: 1280 IKGEKGNPGQPGLPGLPGLKGDQGPPGLQGNPGRPGLNGMKGDPGLPGVPGFPGMKGPSG 1339
Query: 345 TSKLIHPDEDISLEERRAQLPKYQRNLPRP-GQAPIGNPPVGPIGGMMPPQPGI-----P 398
P+ + L P LP P GQ+ I GP G +P QPG+ P
Sbjct: 1340 VPGSAGPEGEPGLIG-----PPGPPGLPGPSGQSIIIKGDAGPPG--IPGQPGLKGLPGP 1392
Query: 399 Q-QQGMRPPMPPHGQYGGHHQGMPGY-----------LPGAMPPYGQGPPMVPPYQGGPP 446
Q QG+ P P G G G+PG+ LPG G P P GPP
Sbjct: 1393 QGPQGLPGPTGPPGDPG--RNGLPGFDGAGGRKGDPGLPGQPGTRGLDGPPGPDGLQGPP 1450
Query: 447 RPP 449
PP
Sbjct: 1451 GPP 1453
Score = 58.9 bits (141), Expect = 9e-09
Identities = 100/380 (26%), Positives = 121/380 (31%), Gaps = 115/380 (30%)
Query: 135 QQGYIPPMAQPGLPPVPGAPGMP-----PGIPPLMPGV--------PPLMPGMPPVMPGM 181
Q G P PG+P PGAPG P PG PG+ P PG+P +PG
Sbjct: 519 QAGATGPKGLPGIPGAPGAPGFPGSKGEPGDILTFPGMKGDKGELGSPGAPGLPG-LPGT 577
Query: 182 P-----PGLHHQRKYTQSFCGENIMMPMGGMMPPGPGIPPLMPGMP--PGMPPPVPRPGI 234
P PGL + GE GG+ G PP PG+P PG P+ PG
Sbjct: 578 PGQDGLPGLPGPK-------GE-----PGGITFKGERGPPGNPGLPGLPGNIGPMGPPGF 625
Query: 235 PPMTQAQAVSAPGILNRPPAPTATVPAPQP--PVTKPLFPSAGQAQAAVQGPVGTDFKPL 292
P G+ P P P P +T+P P G VG L
Sbjct: 626 GPPGPVGEKGIQGVAGNPGQPGIPGPKGDPGQTITQPGKPGL-PGNPGRDGDVG-----L 679
Query: 293 NSTPATTTEPPKPTFPAYTQSTASTTSTTNSTAAKPAASITSKPATLTTTSATSKLIHPD 352
P +P P P + P + P
Sbjct: 680 PGDPGLPGQPGLPGIPG-----------SKGEPGIPGIGLPGPPG--------------- 713
Query: 353 EDISLEERRAQLPKYQRNLPRPGQAPIGNP----------------PVGPIGGMMPPQPG 396
PK +P P AP G P P G G +P PG
Sbjct: 714 ------------PKGFPGIPGPPGAP-GTPGRIGLEGPPGPPGFPGPKGEPGFALPGPPG 760
Query: 397 IPQQQGMRPPMPPHGQYGGHHQGMPG--------YLPGA---MPPYGQGPPMVPP----- 440
P G + + P G G G PG LPG + P GQ PM PP
Sbjct: 761 PPGLPGFKGALGPKGDRG--FPGPPGPPGRTGLDGLPGPKGDVGPNGQPGPMGPPGLPGI 818
Query: 441 YQGGPPRPPMGMRPPVMSQG 460
GPP PP G+ P+ G
Sbjct: 819 GVQGPPGPP-GIPGPIGQPG 837
Score = 58.9 bits (141), Expect = 9e-09
Identities = 100/383 (26%), Positives = 128/383 (33%), Gaps = 72/383 (18%)
Query: 136 QGYIPPMAQPGLPPVPGAPGMP--------PGIPPL-MPGVP-----PLMPGMP------ 175
QG P G+P PG+PG+P PGI + +PG+P P +PG P
Sbjct: 1038 QGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGISSIGLPGLPGPKGEPGLPGYPGNPGIK 1097
Query: 176 -----PVMPGMP--PGLHHQRKYTQSFCGENIMMPMGGMMPPG-PGIP----PLMPGMPP 223
P +PG+P PG Q P G PPG PG+P P+ G P
Sbjct: 1098 GSVGDPGLPGLPGTPGAKGQPGLPGFPGTPGPPGPKGISGPPGNPGLPGEPGPVGGGGHP 1157
Query: 224 GMPPPVPRPGIP-------PMTQAQAVSAPGILNRPPAPTATVPAPQPPVTKPLFPSAGQ 276
G P P G P P Q PG N P + + P P
Sbjct: 1158 GQPGPPGEKGKPGQDGIPGPAGQKGEPGQPGFGNPGPPGLPGLSGQKGDGGLPGIP---- 1213
Query: 277 AQAAVQGPVGTDFKPLNSTPATTTEPPKPTFPAYTQSTASTTSTTNSTAAKPAASITSKP 336
+ GP G + P P P P +P P
Sbjct: 1214 GNPGLPGPKGE--PGFHGFPGVQGPPGPPGSPGPALEGPKGNPGPQGPPGRPGLPGPEGP 1271
Query: 337 ATLTTTSATSKLIHPDEDISLEERRAQLPKYQRNLPRPGQAPIGNPPVGPIGGMM--PPQ 394
L I ++ + LP + + PG GNP + GM P
Sbjct: 1272 PGLPGNGG----IKGEKGNPGQPGLPGLPGLKGDQGPPGLQ--GNPGRPGLNGMKGDPGL 1325
Query: 395 PGIPQQQGMRPPMPPHGQYGGHHQGMPGYL-----PGAMPPYGQ--------GPPMVPPY 441
PG+P GM+ P G G +G PG + PG P GQ GPP +P
Sbjct: 1326 PGVPGFPGMKGPSGVPGSAG--PEGEPGLIGPPGPPGLPGPSGQSIIIKGDAGPPGIPGQ 1383
Query: 442 QG--GPPRP--PMGMRPPVMSQG 460
G G P P P G+ P G
Sbjct: 1384 PGLKGLPGPQGPQGLPGPTGPPG 1406
Score = 58.5 bits (140), Expect = 1e-08
Identities = 97/344 (28%), Positives = 125/344 (36%), Gaps = 60/344 (17%)
Query: 136 QGYIPPMAQPGLPPVPGAPGMPPGIPPL-MPGV--PPLMPGM----PPVMPGMP-----P 183
+G+ P PG + G PG + P PG PP +PG+ PP PG+P P
Sbjct: 777 RGFPGPPGPPGRTGLDGLPGPKGDVGPNGQPGPMGPPGLPGIGVQGPPGPPGIPGPIGQP 836
Query: 184 GLHHQRKYTQSFCGENIMMPMGGMMPPGPGIPPLMPGMPPGMPPPVPRPGIPPMT-QAQA 242
GLH GE G+ PGP PG+ PG P P+ PG P + +A A
Sbjct: 837 GLH-------GIPGEKGDPGPPGLDVPGPPGERGSPGI-PGAPGPIGPPGSPGLPGKAGA 888
Query: 243 VSAPGI-----LNRPPAPTATVPAPQPPVTKPLFPSAG-QAQAAVQGPVGTDFKPLNSTP 296
PG + PP P + P L G Q Q + GP G K P
Sbjct: 889 SGFPGTKGEMGMMGPPGPPGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGE--KGSKGEP 946
Query: 297 ATTTEPPKPTFPAYTQSTASTTSTTNSTAAKPAASITSKPATLTTTSATSKLIHPDE-DI 355
PP P P + S K + P P + +
Sbjct: 947 G-LPGPPGPMDP----------NLLGSKGEKGEPGLPGIPGVSGPKGYQGLPGDPGQPGL 995
Query: 356 SLEERRAQLPKYQRNLPRPGQAPIGNPP-----------VGPIGGMMPPQP-GIPQQQGM 403
S + P + N PGQ + PP GP G PP P G+P Q G
Sbjct: 996 SGQPGLPGPPGPKGNPGLPGQPGLIGPPGLKGTIGDMGFPGPQGVEGPPGPSGVPGQPG- 1054
Query: 404 RPPMPPHGQYGGHHQGMPGYLPGAMP--PYGQGPPMVPPYQGGP 445
P +P GQ G +G PG +P P +G P +P Y G P
Sbjct: 1055 SPGLP--GQKG--DKGDPGISSIGLPGLPGPKGEPGLPGYPGNP 1094
Score = 56.2 bits (134), Expect = 6e-08
Identities = 96/361 (26%), Positives = 124/361 (34%), Gaps = 51/361 (14%)
Query: 135 QQGYIPPMAQPGLPPVPGAPGMPPGIPPLMPGVPPLM--PGMPPVMPGMPPGLHHQRKYT 192
++G+ PGLP PGA M P PP PG G P + PPGL Q
Sbjct: 372 ERGFPGIQGPPGLPGPPGAAVMGPPGPPGFPGERGQKGDEGPPGISIPGPPGLDGQPG-- 429
Query: 193 QSFCGENIMMPMGGMMPPGPGIPPLMPGMPPGMPPPVPRPGIPPMTQAQAVS-------- 244
+ P G P GP IPP PG P P PG + Q V
Sbjct: 430 ----APGLPGPPG---PAGPHIPPSDEICEPGPPGPPGSPGDKGLQGEQGVKGDKGDTCF 482
Query: 245 ---APGILNRPPAPTATVPAPQPPVTKPLFPSAGQ-AQAAVQGPVGTDFKPLNSTPATTT 300
GI + PP P PP + G+ QA GP G P P
Sbjct: 483 NCIGTGI-SGPPGQPGLPGLPGPPGSLGFPGQKGEKGQAGATGPKGLPGIP--GAPGAPG 539
Query: 301 EPPKPTFPAYTQSTASTTSTTNSTAAKPAASITSKPATLTTTSATSKLIHPDEDISLEER 360
P P + + A + P T E + +
Sbjct: 540 FPGSKGEPGDILTFPGMKGDKGELGSPGAPGLPGLPGTPGQDGLPGLPGPKGEPGGITFK 599
Query: 361 RAQLPKYQRNLP-RPGQ-APIGNP---PVGPIG--GMM-----PPQPGIPQQQG------ 402
+ P LP PG P+G P P GP+G G+ P QPGIP +G
Sbjct: 600 GERGPPGNPGLPGLPGNIGPMGPPGFGPPGPVGEKGIQGVAGNPGQPGIPGPKGDPGQTI 659
Query: 403 ---MRPPMPPHGQYGGHHQGMPGYLPGAMPPYGQGPPMVPPYQGGPPRPPMGMRPPVMSQ 459
+P +P + G G+PG PG P G P +P +G P P +G+ P +
Sbjct: 660 TQPGKPGLPGNPGRDG-DVGLPGD-PGL--PGQPGLPGIPGSKGEPGIPGIGLPGPPGPK 715
Query: 460 G 460
G
Sbjct: 716 G 716
Score = 55.5 bits (132), Expect = 1e-07
Identities = 106/402 (26%), Positives = 136/402 (33%), Gaps = 130/402 (32%)
Query: 129 PQPVQPQQGYIPP---MAQPGLPPVPGAPG---------------------------MPP 158
P P P +IPP + +PG P PG+PG PP
Sbjct: 434 PGPPGPAGPHIPPSDEICEPGPPGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGPP 493
Query: 159 GIP--PLMPGVPPLM--PGM-----------PPVMPGMP--------PGLHHQRKYTQSF 195
G P P +PG P + PG P +PG+P PG + +F
Sbjct: 494 GQPGLPGLPGPPGSLGFPGQKGEKGQAGATGPKGLPGIPGAPGAPGFPGSKGEPGDILTF 553
Query: 196 CGENIMMPMGGMMPPG-PGIPPLMPGMP-----PGMPPPVPRPGIPPMTQAQAVSAPGIL 249
G + G + PG PG+P L PG P PG+P P PG +T PG
Sbjct: 554 PG--MKGDKGELGSPGAPGLPGL-PGTPGQDGLPGLPGPKGEPG--GITFKGERGPPGNP 608
Query: 250 NRPPAPTATVPAPQPPVTKPLFPSAGQAQAAVQGPVGTDFKPLNSTP-----ATTTEPPK 304
P P P P P + +QG G +P P T T+P K
Sbjct: 609 GLPGLPGNIGPMGPP----GFGPPGPVGEKGIQGVAGNPGQPGIPGPKGDPGQTITQPGK 664
Query: 305 PTFPAYTQSTASTTSTTNSTAAKPAASITSKPATLTTTSATSKLIHPDEDISLEERRAQL 364
P P + +P L
Sbjct: 665 PGLP-------GNPGRDGDVGLPGDPGLPGQPG--------------------------L 691
Query: 365 PKYQRNLPRPGQAPIGNP-PVGPIG--GM--MPPQPGIPQQQGMRPPMPPHGQYGGHHQG 419
P + PG IG P P GP G G+ P PG P + G+ P P G G +G
Sbjct: 692 PGIPGSKGEPGIPGIGLPGPPGPKGFPGIPGPPGAPGTPGRIGLEGPPGPPGFPG--PKG 749
Query: 420 MPGY-LPGAMPPYGQGPPMVPPYQG-----------GPPRPP 449
PG+ LPG PP GPP +P ++G GPP PP
Sbjct: 750 EPGFALPG--PP---GPPGLPGFKGALGPKGDRGFPGPPGPP 786
Score = 50.8 bits (120), Expect = 3e-06
Identities = 99/357 (27%), Positives = 119/357 (33%), Gaps = 113/357 (31%)
Query: 129 PQPVQPQQGYIPPMAQPGLPPVPGAPGMPPGIPPLMPGVPPLMPGMP-----------PV 177
P PV ++G PG P +PG G PG PG P L PG P P
Sbjct: 628 PGPVG-EKGIQGVAGNPGQPGIPGPKG-DPGQTITQPGKPGL-PGNPGRDGDVGLPGDPG 684
Query: 178 MPGMP--PGLHHQRKYTQSFCGENIMMPMGGMMPPGPGIPPLMPGMPPGMPPPVPRPGI- 234
+PG P PG+ + GE + +G PPGP P +PG PPG P R G+
Sbjct: 685 LPGQPGLPGIPGSK-------GEPGIPGIGLPGPPGPKGFPGIPG-PPGAPGTPGRIGLE 736
Query: 235 -PPMTQAQAVSAPGILNRPPAPTATVPAPQPPVTKPLFPSAGQAQAAVQGPVGTDFKPLN 293
PP PG P +P P P P F A GP G P
Sbjct: 737 GPP-------GPPGFPGPKGEPGFALPGPPGPPGLPGFKGA-------LGPKGDRGFP-- 780
Query: 294 STPATTTEPPKPTFPAYTQSTASTTSTTNSTAAKPAASITSKPATLTTTSATSKLIHPDE 353
PP P T K +P
Sbjct: 781 -------GPPGP---------PGRTGLDGLPGPKGDVGPNGQPG---------------- 808
Query: 354 DISLEERRAQLPKYQRNLPRPG-QAPIGNPPV-GPIG--GM--MPPQPGIPQQQGMRPPM 407
P LP G Q P G P + GPIG G+ +P + G P G+ P
Sbjct: 809 -----------PMGPPGLPGIGVQGPPGPPGIPGPIGQPGLHGIPGEKGDPGPPGLDVPG 857
Query: 408 PPHGQYGGHHQGMPGYLPGAMPPYG-QGPPMVPPYQG--------------GPPRPP 449
PP +G PG +PGA P G G P +P G GPP PP
Sbjct: 858 PP------GERGSPG-IPGAPGPIGPPGSPGLPGKAGASGFPGTKGEMGMMGPPGPP 907
Score = 50.8 bits (120), Expect = 3e-06
Identities = 57/172 (33%), Positives = 68/172 (39%), Gaps = 43/172 (25%)
Query: 145 PGLPPVPGAPGM--PPGIPPLMPGVPPLMPGM--PPVMPGMPPGLHHQRKYTQSFCGENI 200
PGLP VPG PGM P G+P P PG+ PP PG+P G++I
Sbjct: 1323 PGLPGVPGFPGMKGPSGVPG--SAGPEGEPGLIGPPGPPGLP-----------GPSGQSI 1369
Query: 201 MMPMGGMMPPG-PGIPPL--MPGM--PPGMPPPVPRPGIPPMTQAQAVSA-------PGI 248
++ G PPG PG P L +PG P G+P P PG P PG+
Sbjct: 1370 II-KGDAGPPGIPGQPGLKGLPGPQGPQGLPGPTGPPGDPGRNGLPGFDGAGGRKGDPGL 1428
Query: 249 --------LNRPPAPTATVPAPQPPVTKP-----LFPSAGQAQAAVQGPVGT 287
L+ PP P P PP T L Q A Q P GT
Sbjct: 1429 PGQPGTRGLDGPPGPDGLQGPPGPPGTSSVAHGFLITRHSQTTDAPQCPQGT 1480
Score = 43.5 bits (101), Expect = 4e-04
Identities = 47/151 (31%), Positives = 58/151 (38%), Gaps = 31/151 (20%)
Query: 131 PVQPQQGYIPPMAQPGLPPVPGAPGMP-PGIPPLMPGVPPLM-----PGMP--PVMPGM- 181
P P P PG PG PG+P P PP +PG + PG P P +PG+
Sbjct: 1240 PGSPGPALEGPKGNPGPQGPPGRPGLPGPEGPPGLPGNGGIKGEKGNPGQPGLPGLPGLK 1299
Query: 182 ----PPGLHHQRKYTQSFCGENIMMPMGGMMPPGPGIPPLMPGMPPGMPPPVPRPGIPPM 237
PPGL N P M PG+P +PG PGM P PG
Sbjct: 1300 GDQGPPGLQ-----------GNPGRPGLNGMKGDPGLPG-VPGF-PGMKGPSGVPG---- 1342
Query: 238 TQAQAVSAPGILNRPPAPTATVPAPQPPVTK 268
A PG++ P P P+ Q + K
Sbjct: 1343 -SAGPEGEPGLIGPPGPPGLPGPSGQSIIIK 1372
Score = 36.2 bits (82), Expect = 0.065
Identities = 37/121 (30%), Positives = 45/121 (37%), Gaps = 39/121 (32%)
Query: 369 RNLPRPGQAPIGNPPVGPIGGMMPP-QPGIPQ-----------------QQGMRPPMPPH 410
+ LP P P P GP G M PP PG+P +QG++ P P
Sbjct: 182 QGLPGPTGIPGPIGPPGPPGLMGPPGPPGLPGPKGNMGLNFQGPKGEKGEQGLQGPPGPP 241
Query: 411 GQYGGHH-----------QGMPGYLPGAMPPYGQGPPMVPPYQGGPPRPPMGMRPPVMSQ 459
GQ QG+PG +GPP PP GPP PP G + Q
Sbjct: 242 GQISEQKRPIDVEFQKGDQGLPG---------DRGPPG-PPGIRGPPGPPGGEKGEKGEQ 291
Query: 460 G 460
G
Sbjct: 292 G 292
Score = 35.0 bits (79), Expect = 0.14
Identities = 38/98 (38%), Positives = 40/98 (40%), Gaps = 21/98 (21%)
Query: 372 PRPGQAPIGNPPVGPIGGMMPPQPGIPQQQGMRPPMPP-----HGQYGG-------HHQG 419
P P P N G G P PG P QG PP PP G+ G +G
Sbjct: 116 PGPQGIPGCNGTKGERG--FPGSPGFPGLQG--PPGPPGIPGMKGEPGSIIMSSLPGPKG 171
Query: 420 MPGYLPGAMPPYGQGPPMVPPYQG--GPPRPPMGMRPP 455
PGY PG PP QG P G GPP PP M PP
Sbjct: 172 NPGY-PG--PPGIQGLPGPTGIPGPIGPPGPPGLMGPP 206
Score = 33.9 bits (76), Expect = 0.32
Identities = 23/56 (41%), Positives = 28/56 (50%), Gaps = 5/56 (8%)
Query: 395 PGIPQQQGMRPPMPPHGQYGGHHQGMPGYLPGAMPPYGQGPPMVPPYQGGPPRPPM 450
PG+P G P P GQ G G+PG PG P +GPP +P + G P P M
Sbjct: 59 PGLPGFPGPEGPPGPRGQKG--DDGIPG-PPG--PKGIRGPPGLPGFPGTPGLPGM 109
>gi|15890088 type IV collagen alpha 5 isoform 3 precursor [Homo
sapiens]
Length = 1688
Score = 73.6 bits (179), Expect = 4e-13
Identities = 100/388 (25%), Positives = 130/388 (33%), Gaps = 78/388 (20%)
Query: 129 PQPVQPQQGYIPPMAQPGLPPVPGAPGMP-----PGIPPLMPGVP--------PLMPGMP 175
P P P+ G P PG P PG PGMP PG P +PG P PG P
Sbjct: 83 PGPPGPK-GIRGPPGLPGFPGTPGLPGMPGHDGAPG-PQGIPGCNGTKGERGFPGSPGFP 140
Query: 176 PVM-PGMPPGLHHQRKYTQSFCGENIMMPMGGMMPPGP----------GIP-PLMPGMPP 223
+ P PPG+ + S ++ P G PGP GIP P+ P PP
Sbjct: 141 GLQGPPGPPGIPGMKGEPGSIIMSSLPGPKGNPGYPGPPGIQGLPGPTGIPGPIGPPGPP 200
Query: 224 GMPPPVPRPGIPPMTQAQAVSAPGI--------LNRPPAPTATV---------------- 259
G+ P PG+P ++ G L PP P +
Sbjct: 201 GLMGPPGPPGLPGPKGNMGLNFQGPKGEKGEQGLQGPPGPPGQISEQKRPIDVEFQKGDQ 260
Query: 260 -------PAPQPPVTKPLFPSAGQ-AQAAVQGPVGTDFKP----LNSTPATTTEPPKPTF 307
P P + P P G+ + QG G KP N P P P +
Sbjct: 261 GLPGDRGPPGPPGIRGPPGPPGGEKGEKGEQGEPGKRGKPGKDGENGQPGIPGLPGDPGY 320
Query: 308 PAYTQSTASTTSTTNSTAAKPAASITSKPATLTTTSATSKLIHPDEDISLEERRAQLPKY 367
P ++ P + +P T T + P ER +
Sbjct: 321 PGEPGRDGEKGQKGDTGPPGPPGLVIPRPGTGITIGEKGNIGLPGLPGEKGERGFPGIQG 380
Query: 368 QRNLPRPGQAPIGNPPVGPIGGMMPPQPGIPQQQGMRPPMPPHGQYGGHHQGMPGY--LP 425
LP P A + PP GP PG P ++G + P G G+ G P
Sbjct: 381 PPGLPGPPGAAVMGPP-GP--------PGFPGERGQKGDEGPPGISIPGPPGLDGQPGAP 431
Query: 426 GAMPPYGQGPPMVPP----YQGGPPRPP 449
G P G P +PP + GPP PP
Sbjct: 432 GLPGPPGPAGPHIPPSDEICEPGPPGPP 459
Score = 68.2 bits (165), Expect = 2e-11
Identities = 104/375 (27%), Positives = 127/375 (33%), Gaps = 96/375 (25%)
Query: 141 PMAQPGLPPVPGAPGMPPGI----PPLMPGVP----------PLMPGMPPVMPGMPPGLH 186
P PG+P PGAPG P I PP PG P P PG PP +PG L
Sbjct: 714 PKGFPGIPGPPGAPGTPGRIGLEGPPGPPGFPGPKGEPGFALPGPPG-PPGLPGFKGALG 772
Query: 187 HQRKYTQSFCG----------ENIMMPMGGMMP---PGPGIPPLMPGM-------PPGMP 226
K + F G + + P G + P PGP PP +PG+ PPG+P
Sbjct: 773 P--KGDRGFPGPPGPPGRTGLDGLPGPKGDVGPNGQPGPMGPPGLPGIGVQGPPGPPGIP 830
Query: 227 PPVPRPGIPPMTQAQAVSAPGILNRPPAPTATVPAPQPPVTKPLFPSAGQAQAAVQGPVG 286
P+ +PG+ PG P P VP P P P A GP+G
Sbjct: 831 GPIGQPGLH--------GIPGEKGDPGPPGLDVPGPPGERGSPGIPGA-------PGPIG 875
Query: 287 TDFKP-------LNSTPATTTE-----PPKPTFPA---------------YTQSTASTTS 319
P + P T E PP P P Q
Sbjct: 876 PPGSPGLPGKAGASGFPGTKGEMGMMGPPGPPGPLGIPGRSGVPGLKGDDGLQGQPGLPG 935
Query: 320 TTNSTAAKPAASITSKPATLTTTSATSKLIHPDEDISLEERRAQLPKYQRNLP-RPGQAP 378
T +K + P + SK + + PK + LP PGQ
Sbjct: 936 PTGEKGSKGEPGLPGPPGPMDPNLLGSKGEKGEPGLP-GIPGVSGPKGYQGLPGDPGQPG 994
Query: 379 I-GNP----PVGPIGGMMPPQPGIPQQQGMRPPMPPHGQYGGHHQGMPGYLPGAMPPYGQ 433
+ G P P GP G PG+P Q G+ P G G G PG PP
Sbjct: 995 LSGQPGLPGPPGPKG-----NPGLPGQPGLIGPPGLKGTIG--DMGFPGPQGVEGPP--- 1044
Query: 434 GPPMVPPYQGGPPRP 448
GP VP G P P
Sbjct: 1045 GPSGVPGQPGSPGLP 1059
Score = 65.9 bits (159), Expect = 8e-11
Identities = 90/314 (28%), Positives = 116/314 (36%), Gaps = 47/314 (14%)
Query: 145 PGLPPVPGAPGMPPGIP-PLMPGVPPLMPGMPPVMPGMPPGLHHQRKYTQSFCGENIMMP 203
PG P PG G PG+P P P P +PG P ++ PPGL K T G P
Sbjct: 987 PGDPGQPGLSGQ-PGLPGPPGPKGNPGLPGQPGLIG--PPGL----KGTIGDMG--FPGP 1037
Query: 204 MGGMMPPGPGIPPLMPGMP--PGMPPPVPRPGIPPMTQAQAVSAPGILNRPPAPTATVPA 261
G PPGP P PG P PG PGI ++ PG+ P
Sbjct: 1038 QGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGI------SSIGLPGL-----------PG 1080
Query: 262 PQPPVTKPLFPSAGQAQAAVQGPVGTDFKP-LNSTPATTTEPPKPTFPAYTQSTASTTST 320
P+ P +P ++G VG P L TP +P P FP T
Sbjct: 1081 PKGEPGLPGYP----GNPGIKGSVGDPGLPGLPGTPGAKGQPGLPGFP----GTPGPPGP 1132
Query: 321 TNSTAAKPAASITSKPATLTTTSATSKLIHPDEDISLEERRAQLPKYQRNLPRPGQAPIG 380
+ + +P + + P E + P Q+ PGQ G
Sbjct: 1133 KGISGPPGNPGLPGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGPAGQKG--EPGQPGFG 1190
Query: 381 NPPVGPIGGMMPPQ-----PGIPQQQGMRPPMPPHGQYG-GHHQGMPGYLPGAMPPYGQG 434
NP + G+ + PGIP G+ P G +G QG PG PG+ P +G
Sbjct: 1191 NPGPPGLPGLSGQKGDGGLPGIPGNPGLPGPKGEPGFHGFPGVQGPPG-PPGSPGPALEG 1249
Query: 435 PPMVPPYQGGPPRP 448
P P QG P RP
Sbjct: 1250 PKGNPGPQGPPGRP 1263
Score = 63.2 bits (152), Expect = 5e-10
Identities = 103/366 (28%), Positives = 128/366 (34%), Gaps = 86/366 (23%)
Query: 144 QPGLPPVPGAPGMPPGI-----PPLMPGVP----PLMPGMPPVMPGMPPGLHHQRKYTQS 194
QPGLP PG PG PPG PP PG+P P+ G P PG PPG + K Q
Sbjct: 1117 QPGLPGFPGTPG-PPGPKGISGPPGNPGLPGEPGPVGGGGHPGQPG-PPG--EKGKPGQ- 1171
Query: 195 FCGENIMMPMGGMMPPG---------PGIPPL--------MPGMP--PGMPPPVPRPGIP 235
+ I P G PG PG+P L +PG+P PG+P P PG
Sbjct: 1172 ---DGIPGPAGQKGEPGQPGFGNPGPPGLPGLSGQKGDGGLPGIPGNPGLPGPKGEPGFH 1228
Query: 236 PMTQAQAVSAPGILNRPPAPTATVPAPQPPVTKPLFPSAGQAQAAVQGPVGTDFKP---- 291
PG+ P P + PA + P P P + QG G + P
Sbjct: 1229 --------GFPGVQGPPGPPGSPGPALEGPKGNP-GPQGPPGRPGFQGLPGPEGPPGLPG 1279
Query: 292 ---LNSTPATTTEPPKPTFPAYTQSTASTTSTTNS-----TAAKPAASITSKPA--TLTT 341
+ +P P P N K + P +
Sbjct: 1280 NGGIKGEKGNPGQPGLPGLPGLKGDQGPPGLQGNPGRPGLNGMKGDPGLPGVPGFPGMKG 1339
Query: 342 TSATSKLIHPDEDISLEERRAQLPKYQRNLPRP-GQAPIGNPPVGPIGGMMPPQPGI--- 397
S P+ + L P LP P GQ+ I GP G +P QPG+
Sbjct: 1340 PSGVPGSAGPEGEPGLIG-----PPGPPGLPGPSGQSIIIKGDAGPPG--IPGQPGLKGL 1392
Query: 398 --PQ-QQGMRPPMPPHGQYGGHHQGMPGY-----------LPGAMPPYGQGPPMVPPYQG 443
PQ QG+ P P G G G+PG+ LPG G P P
Sbjct: 1393 PGPQGPQGLPGPTGPPGDPG--RNGLPGFDGAGGRKGDPGLPGQPGTRGLDGPPGPDGLQ 1450
Query: 444 GPPRPP 449
GPP PP
Sbjct: 1451 GPPGPP 1456
Score = 58.9 bits (141), Expect = 9e-09
Identities = 100/380 (26%), Positives = 121/380 (31%), Gaps = 115/380 (30%)
Query: 135 QQGYIPPMAQPGLPPVPGAPGMP-----PGIPPLMPGV--------PPLMPGMPPVMPGM 181
Q G P PG+P PGAPG P PG PG+ P PG+P +PG
Sbjct: 519 QAGATGPKGLPGIPGAPGAPGFPGSKGEPGDILTFPGMKGDKGELGSPGAPGLPG-LPGT 577
Query: 182 P-----PGLHHQRKYTQSFCGENIMMPMGGMMPPGPGIPPLMPGMP--PGMPPPVPRPGI 234
P PGL + GE GG+ G PP PG+P PG P+ PG
Sbjct: 578 PGQDGLPGLPGPK-------GE-----PGGITFKGERGPPGNPGLPGLPGNIGPMGPPGF 625
Query: 235 PPMTQAQAVSAPGILNRPPAPTATVPAPQP--PVTKPLFPSAGQAQAAVQGPVGTDFKPL 292
P G+ P P P P +T+P P G VG L
Sbjct: 626 GPPGPVGEKGIQGVAGNPGQPGIPGPKGDPGQTITQPGKPGL-PGNPGRDGDVG-----L 679
Query: 293 NSTPATTTEPPKPTFPAYTQSTASTTSTTNSTAAKPAASITSKPATLTTTSATSKLIHPD 352
P +P P P + P + P
Sbjct: 680 PGDPGLPGQPGLPGIPG-----------SKGEPGIPGIGLPGPPG--------------- 713
Query: 353 EDISLEERRAQLPKYQRNLPRPGQAPIGNP----------------PVGPIGGMMPPQPG 396
PK +P P AP G P P G G +P PG
Sbjct: 714 ------------PKGFPGIPGPPGAP-GTPGRIGLEGPPGPPGFPGPKGEPGFALPGPPG 760
Query: 397 IPQQQGMRPPMPPHGQYGGHHQGMPG--------YLPGA---MPPYGQGPPMVPP----- 440
P G + + P G G G PG LPG + P GQ PM PP
Sbjct: 761 PPGLPGFKGALGPKGDRG--FPGPPGPPGRTGLDGLPGPKGDVGPNGQPGPMGPPGLPGI 818
Query: 441 YQGGPPRPPMGMRPPVMSQG 460
GPP PP G+ P+ G
Sbjct: 819 GVQGPPGPP-GIPGPIGQPG 837
Score = 58.5 bits (140), Expect = 1e-08
Identities = 97/344 (28%), Positives = 125/344 (36%), Gaps = 60/344 (17%)
Query: 136 QGYIPPMAQPGLPPVPGAPGMPPGIPPL-MPGV--PPLMPGM----PPVMPGMP-----P 183
+G+ P PG + G PG + P PG PP +PG+ PP PG+P P
Sbjct: 777 RGFPGPPGPPGRTGLDGLPGPKGDVGPNGQPGPMGPPGLPGIGVQGPPGPPGIPGPIGQP 836
Query: 184 GLHHQRKYTQSFCGENIMMPMGGMMPPGPGIPPLMPGMPPGMPPPVPRPGIPPMT-QAQA 242
GLH GE G+ PGP PG+ PG P P+ PG P + +A A
Sbjct: 837 GLH-------GIPGEKGDPGPPGLDVPGPPGERGSPGI-PGAPGPIGPPGSPGLPGKAGA 888
Query: 243 VSAPGI-----LNRPPAPTATVPAPQPPVTKPLFPSAG-QAQAAVQGPVGTDFKPLNSTP 296
PG + PP P + P L G Q Q + GP G K P
Sbjct: 889 SGFPGTKGEMGMMGPPGPPGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGE--KGSKGEP 946
Query: 297 ATTTEPPKPTFPAYTQSTASTTSTTNSTAAKPAASITSKPATLTTTSATSKLIHPDE-DI 355
PP P P + S K + P P + +
Sbjct: 947 G-LPGPPGPMDP----------NLLGSKGEKGEPGLPGIPGVSGPKGYQGLPGDPGQPGL 995
Query: 356 SLEERRAQLPKYQRNLPRPGQAPIGNPP-----------VGPIGGMMPPQP-GIPQQQGM 403
S + P + N PGQ + PP GP G PP P G+P Q G
Sbjct: 996 SGQPGLPGPPGPKGNPGLPGQPGLIGPPGLKGTIGDMGFPGPQGVEGPPGPSGVPGQPG- 1054
Query: 404 RPPMPPHGQYGGHHQGMPGYLPGAMP--PYGQGPPMVPPYQGGP 445
P +P GQ G +G PG +P P +G P +P Y G P
Sbjct: 1055 SPGLP--GQKG--DKGDPGISSIGLPGLPGPKGEPGLPGYPGNP 1094
Score = 56.2 bits (134), Expect = 6e-08
Identities = 96/361 (26%), Positives = 124/361 (34%), Gaps = 51/361 (14%)
Query: 135 QQGYIPPMAQPGLPPVPGAPGMPPGIPPLMPGVPPLM--PGMPPVMPGMPPGLHHQRKYT 192
++G+ PGLP PGA M P PP PG G P + PPGL Q
Sbjct: 372 ERGFPGIQGPPGLPGPPGAAVMGPPGPPGFPGERGQKGDEGPPGISIPGPPGLDGQPG-- 429
Query: 193 QSFCGENIMMPMGGMMPPGPGIPPLMPGMPPGMPPPVPRPGIPPMTQAQAVS-------- 244
+ P G P GP IPP PG P P PG + Q V
Sbjct: 430 ----APGLPGPPG---PAGPHIPPSDEICEPGPPGPPGSPGDKGLQGEQGVKGDKGDTCF 482
Query: 245 ---APGILNRPPAPTATVPAPQPPVTKPLFPSAGQ-AQAAVQGPVGTDFKPLNSTPATTT 300
GI + PP P PP + G+ QA GP G P P
Sbjct: 483 NCIGTGI-SGPPGQPGLPGLPGPPGSLGFPGQKGEKGQAGATGPKGLPGIP--GAPGAPG 539
Query: 301 EPPKPTFPAYTQSTASTTSTTNSTAAKPAASITSKPATLTTTSATSKLIHPDEDISLEER 360
P P + + A + P T E + +
Sbjct: 540 FPGSKGEPGDILTFPGMKGDKGELGSPGAPGLPGLPGTPGQDGLPGLPGPKGEPGGITFK 599
Query: 361 RAQLPKYQRNLP-RPGQ-APIGNP---PVGPIG--GMM-----PPQPGIPQQQG------ 402
+ P LP PG P+G P P GP+G G+ P QPGIP +G
Sbjct: 600 GERGPPGNPGLPGLPGNIGPMGPPGFGPPGPVGEKGIQGVAGNPGQPGIPGPKGDPGQTI 659
Query: 403 ---MRPPMPPHGQYGGHHQGMPGYLPGAMPPYGQGPPMVPPYQGGPPRPPMGMRPPVMSQ 459
+P +P + G G+PG PG P G P +P +G P P +G+ P +
Sbjct: 660 TQPGKPGLPGNPGRDG-DVGLPGD-PGL--PGQPGLPGIPGSKGEPGIPGIGLPGPPGPK 715
Query: 460 G 460
G
Sbjct: 716 G 716
Score = 55.8 bits (133), Expect = 8e-08
Identities = 94/338 (27%), Positives = 123/338 (36%), Gaps = 72/338 (21%)
Query: 136 QGYIPPMAQPGLPPVPGAPGMP--------PGIPPL-MPGVPPLMPGMPPVMPGMP--PG 184
QG P G+P PG+PG+P PGI + +PG+P P P +PG P PG
Sbjct: 1038 QGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGISSIGLPGLPG--PKGEPGLPGYPGNPG 1095
Query: 185 LHHQRKYTQSFCGENIMMPMGGMMPPGPGIPPLMPGMPPGMPPPVPRPGIPPMTQAQAVS 244
+ G + PG +PG+ PG P +PG+P
Sbjct: 1096 I------------------KGSVGDPG------LPGL-PGTPGAKGQPGLPGFP-----G 1125
Query: 245 APGILNRPPAPTA-TVPAPQPPVTKPLFPSAGQAQAAVQGPVGTDFKP-LNSTPATTTEP 302
PG PP P + P P + P G GP G KP + P +
Sbjct: 1126 TPG----PPGPKGISGPPGNPGLPGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGPAGQK 1181
Query: 303 PKPTFPAYTQSTASTTSTTNSTAAKPAASITSKPATLTTTSATSKLIHPDEDISLEE-RR 361
+P P + P S L L P +
Sbjct: 1182 GEPGQPGFGNP---------GPPGLPGLSGQKGDGGLPGIPGNPGLPGPKGEPGFHGFPG 1232
Query: 362 AQLPKYQRNLPRPG-QAPIGNP-PVGPIGGMMPPQPGIPQQQGMRPPMPPHGQYGGH--H 417
Q P P P + P GNP P GP G P G+P +G P +P +G G +
Sbjct: 1233 VQGPPGPPGSPGPALEGPKGNPGPQGPPG--RPGFQGLPGPEG-PPGLPGNGGIKGEKGN 1289
Query: 418 QGMPGYLPGAMPPYG-QGPPMVPPYQGGPPRPPM-GMR 453
G PG LPG G QGPP + QG P RP + GM+
Sbjct: 1290 PGQPG-LPGLPGLKGDQGPPGL---QGNPGRPGLNGMK 1323
Score = 55.5 bits (132), Expect = 1e-07
Identities = 106/402 (26%), Positives = 136/402 (33%), Gaps = 130/402 (32%)
Query: 129 PQPVQPQQGYIPP---MAQPGLPPVPGAPG---------------------------MPP 158
P P P +IPP + +PG P PG+PG PP
Sbjct: 434 PGPPGPAGPHIPPSDEICEPGPPGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGPP 493
Query: 159 GIP--PLMPGVPPLM--PGM-----------PPVMPGMP--------PGLHHQRKYTQSF 195
G P P +PG P + PG P +PG+P PG + +F
Sbjct: 494 GQPGLPGLPGPPGSLGFPGQKGEKGQAGATGPKGLPGIPGAPGAPGFPGSKGEPGDILTF 553
Query: 196 CGENIMMPMGGMMPPG-PGIPPLMPGMP-----PGMPPPVPRPGIPPMTQAQAVSAPGIL 249
G + G + PG PG+P L PG P PG+P P PG +T PG
Sbjct: 554 PG--MKGDKGELGSPGAPGLPGL-PGTPGQDGLPGLPGPKGEPG--GITFKGERGPPGNP 608
Query: 250 NRPPAPTATVPAPQPPVTKPLFPSAGQAQAAVQGPVGTDFKPLNSTP-----ATTTEPPK 304
P P P P P + +QG G +P P T T+P K
Sbjct: 609 GLPGLPGNIGPMGPP----GFGPPGPVGEKGIQGVAGNPGQPGIPGPKGDPGQTITQPGK 664
Query: 305 PTFPAYTQSTASTTSTTNSTAAKPAASITSKPATLTTTSATSKLIHPDEDISLEERRAQL 364
P P + +P L
Sbjct: 665 PGLP-------GNPGRDGDVGLPGDPGLPGQPG--------------------------L 691
Query: 365 PKYQRNLPRPGQAPIGNP-PVGPIG--GM--MPPQPGIPQQQGMRPPMPPHGQYGGHHQG 419
P + PG IG P P GP G G+ P PG P + G+ P P G G +G
Sbjct: 692 PGIPGSKGEPGIPGIGLPGPPGPKGFPGIPGPPGAPGTPGRIGLEGPPGPPGFPG--PKG 749
Query: 420 MPGY-LPGAMPPYGQGPPMVPPYQG-----------GPPRPP 449
PG+ LPG PP GPP +P ++G GPP PP
Sbjct: 750 EPGFALPG--PP---GPPGLPGFKGALGPKGDRGFPGPPGPP 786
Score = 52.4 bits (124), Expect = 9e-07
Identities = 104/382 (27%), Positives = 130/382 (34%), Gaps = 86/382 (22%)
Query: 141 PMAQPGLPPVPGAPGMPPGIPPL-MPGVP-----PLMPGMP-PVMPGMPPGLHHQRKYTQ 193
P+ QPGL +PG G PG P L +PG P P +PG P P+ P PGL + +
Sbjct: 832 PIGQPGLHGIPGEKG-DPGPPGLDVPGPPGERGSPGIPGAPGPIGPPGSPGLPGKAGASG 890
Query: 194 SFCGENIMMPMGGMMPPGP-------GIPPL--------MPGMP-----------PGMP- 226
+ M MG PPGP G+P L PG+P PG+P
Sbjct: 891 FPGTKGEMGMMGPPGPPGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPG 950
Query: 227 PPVPR----------------PGIPPMTQAQAVSA-------PGI-----LNRPPAPTAT 258
PP P PGIP ++ + PG+ L PP P
Sbjct: 951 PPGPMDPNLLGSKGEKGEPGLPGIPGVSGPKGYQGLPGDPGQPGLSGQPGLPGPPGPKGN 1010
Query: 259 VPAP-QPPVTKPLFPSAGQAQAAVQGPVGTDFKPLNSTPATTTEPPKPTFPAYTQSTAST 317
P QP + P GP G + P + P +P P
Sbjct: 1011 PGLPGQPGLIGPPGLKGTIGDMGFPGPQGVE-----GPPGPSGVPGQPGSPGLPGQKGDK 1065
Query: 318 TSTTNSTAAKPAASITSKPATLTTTSATSKLIHPDEDISLEERRAQLPKYQRNLPRPGQA 377
S+ P L + D L LP +PG
Sbjct: 1066 GDPGISSIGLPGLPGPKGEPGLPGYPGNPGIKGSVGDPGLPG----LPGTPGAKGQPGLP 1121
Query: 378 PI-GNP-PVGPIGGMMPP-QPGIPQQQGMRPPMPPHGQYGGHHQGMPGYLPGAMPPYGQ- 433
G P P GP G PP PG+P + G P G GG H G PG PG GQ
Sbjct: 1122 GFPGTPGPPGPKGISGPPGNPGLPGEPG------PVG--GGGHPGQPG-PPGEKGKPGQD 1172
Query: 434 GPPMVPPYQGGPPRPPMGMRPP 455
G P +G P +P G P
Sbjct: 1173 GIPGPAGQKGEPGQPGFGNPGP 1194
Score = 50.8 bits (120), Expect = 3e-06
Identities = 99/357 (27%), Positives = 119/357 (33%), Gaps = 113/357 (31%)
Query: 129 PQPVQPQQGYIPPMAQPGLPPVPGAPGMPPGIPPLMPGVPPLMPGMP-----------PV 177
P PV ++G PG P +PG G PG PG P L PG P P
Sbjct: 628 PGPVG-EKGIQGVAGNPGQPGIPGPKG-DPGQTITQPGKPGL-PGNPGRDGDVGLPGDPG 684
Query: 178 MPGMP--PGLHHQRKYTQSFCGENIMMPMGGMMPPGPGIPPLMPGMPPGMPPPVPRPGI- 234
+PG P PG+ + GE + +G PPGP P +PG PPG P R G+
Sbjct: 685 LPGQPGLPGIPGSK-------GEPGIPGIGLPGPPGPKGFPGIPG-PPGAPGTPGRIGLE 736
Query: 235 -PPMTQAQAVSAPGILNRPPAPTATVPAPQPPVTKPLFPSAGQAQAAVQGPVGTDFKPLN 293
PP PG P +P P P P F A GP G P
Sbjct: 737 GPP-------GPPGFPGPKGEPGFALPGPPGPPGLPGFKGA-------LGPKGDRGFP-- 780
Query: 294 STPATTTEPPKPTFPAYTQSTASTTSTTNSTAAKPAASITSKPATLTTTSATSKLIHPDE 353
PP P T K +P
Sbjct: 781 -------GPPGP---------PGRTGLDGLPGPKGDVGPNGQPG---------------- 808
Query: 354 DISLEERRAQLPKYQRNLPRPG-QAPIGNPPV-GPIG--GM--MPPQPGIPQQQGMRPPM 407
P LP G Q P G P + GPIG G+ +P + G P G+ P
Sbjct: 809 -----------PMGPPGLPGIGVQGPPGPPGIPGPIGQPGLHGIPGEKGDPGPPGLDVPG 857
Query: 408 PPHGQYGGHHQGMPGYLPGAMPPYG-QGPPMVPPYQG--------------GPPRPP 449
PP +G PG +PGA P G G P +P G GPP PP
Sbjct: 858 PP------GERGSPG-IPGAPGPIGPPGSPGLPGKAGASGFPGTKGEMGMMGPPGPP 907
Score = 50.8 bits (120), Expect = 3e-06
Identities = 57/172 (33%), Positives = 68/172 (39%), Gaps = 43/172 (25%)
Query: 145 PGLPPVPGAPGM--PPGIPPLMPGVPPLMPGM--PPVMPGMPPGLHHQRKYTQSFCGENI 200
PGLP VPG PGM P G+P P PG+ PP PG+P G++I
Sbjct: 1326 PGLPGVPGFPGMKGPSGVPG--SAGPEGEPGLIGPPGPPGLP-----------GPSGQSI 1372
Query: 201 MMPMGGMMPPG-PGIPPL--MPGM--PPGMPPPVPRPGIPPMTQAQAVSA-------PGI 248
++ G PPG PG P L +PG P G+P P PG P PG+
Sbjct: 1373 II-KGDAGPPGIPGQPGLKGLPGPQGPQGLPGPTGPPGDPGRNGLPGFDGAGGRKGDPGL 1431
Query: 249 --------LNRPPAPTATVPAPQPPVTKP-----LFPSAGQAQAAVQGPVGT 287
L+ PP P P PP T L Q A Q P GT
Sbjct: 1432 PGQPGTRGLDGPPGPDGLQGPPGPPGTSSVAHGFLITRHSQTTDAPQCPQGT 1483
Score = 36.2 bits (82), Expect = 0.065
Identities = 37/121 (30%), Positives = 45/121 (37%), Gaps = 39/121 (32%)
Query: 369 RNLPRPGQAPIGNPPVGPIGGMMPP-QPGIPQ-----------------QQGMRPPMPPH 410
+ LP P P P GP G M PP PG+P +QG++ P P
Sbjct: 182 QGLPGPTGIPGPIGPPGPPGLMGPPGPPGLPGPKGNMGLNFQGPKGEKGEQGLQGPPGPP 241
Query: 411 GQYGGHH-----------QGMPGYLPGAMPPYGQGPPMVPPYQGGPPRPPMGMRPPVMSQ 459
GQ QG+PG +GPP PP GPP PP G + Q
Sbjct: 242 GQISEQKRPIDVEFQKGDQGLPG---------DRGPPG-PPGIRGPPGPPGGEKGEKGEQ 291
Query: 460 G 460
G
Sbjct: 292 G 292
Score = 35.0 bits (79), Expect = 0.14
Identities = 38/98 (38%), Positives = 40/98 (40%), Gaps = 21/98 (21%)
Query: 372 PRPGQAPIGNPPVGPIGGMMPPQPGIPQQQGMRPPMPP-----HGQYGG-------HHQG 419
P P P N G G P PG P QG PP PP G+ G +G
Sbjct: 116 PGPQGIPGCNGTKGERG--FPGSPGFPGLQG--PPGPPGIPGMKGEPGSIIMSSLPGPKG 171
Query: 420 MPGYLPGAMPPYGQGPPMVPPYQG--GPPRPPMGMRPP 455
PGY PG PP QG P G GPP PP M PP
Sbjct: 172 NPGY-PG--PPGIQGLPGPTGIPGPIGPPGPPGLMGPP 206
Score = 33.9 bits (76), Expect = 0.32
Identities = 23/56 (41%), Positives = 28/56 (50%), Gaps = 5/56 (8%)
Query: 395 PGIPQQQGMRPPMPPHGQYGGHHQGMPGYLPGAMPPYGQGPPMVPPYQGGPPRPPM 450
PG+P G P P GQ G G+PG PG P +GPP +P + G P P M
Sbjct: 59 PGLPGFPGPEGPPGPRGQKG--DDGIPG-PPG--PKGIRGPPGLPGFPGTPGLPGM 109
>gi|42544130 splicing factor 1 isoform 1 [Homo sapiens]
Length = 639
Score = 73.6 bits (179), Expect = 4e-13
Identities = 84/328 (25%), Positives = 106/328 (32%), Gaps = 30/328 (9%)
Query: 138 YIPPMAQPGLPPVPGAPGMP--PGIPPLMPGVPPLMPGMPPVMPGMPPGLHHQRKYTQSF 195
Y+ MA+ G PVP + G P PL P P P P + + + S
Sbjct: 313 YLSLMAELGEAPVPASVGSTSGPATTPLASAPRPAAPANNPPPPSLMSTTQSRPPWMNS- 371
Query: 196 CGENIMMPMGGMMPPGPGIP---------PL-----------MPGMPPGMPPPVPRPGIP 235
G + P GM GPG P PL M P G PPP +P P
Sbjct: 372 -GPSESRPYHGMHGGGPGGPGGGPHSFPHPLPSLTGGHGGHPMQHNPNGPPPPWMQPPPP 430
Query: 236 PMTQAQAVSAPGILNRPPAPTATVPAPQPPVTKPLFPSAGQAQAAVQGPVGTDFKPLNST 295
PM Q PG PP P L G G + P +
Sbjct: 431 PMNQGP--HPPGHHGPPPMDQYLGSTPVGSGVYRLHQGKGMMPPPPMGMMPPPPPPPSGQ 488
Query: 296 PATTTEPPKPTFPAYTQSTASTTSTTNSTAAKPAASITSKPATLTTTSATSKLIHPDEDI 355
P P P + Q ++S A+ T TT++ T + +
Sbjct: 489 PPPPPSGPLPPWQQQQQQPPPPPPPSSSMASSTPLPWQQNTTTTTTSAGTGSIPPWQQQQ 548
Query: 356 SLEERRAQLPKYQRNLPRPGQAPIGNPPVGPIGGMMPPQPGIPQQQGMR---PPMPPHGQ 412
+ P+ Q N P P G P P G PP P P GM PP PP
Sbjct: 549 AAAAASPGAPQMQGN-PTMVPLPPGVQPPLPPGAPPPPPPPPPGSAGMMYAPPPPPPPPM 607
Query: 413 YGGHHQGMPGYLPGAMPPYGQGPPMVPP 440
+ M G MPP+G P PP
Sbjct: 608 DPSNFVTMMGMGVAGMPPFGMPPAPPPP 635
Score = 56.2 bits (134), Expect = 6e-08
Identities = 56/182 (30%), Positives = 72/182 (39%), Gaps = 34/182 (18%)
Query: 308 PAYTQSTASTTSTTNSTAAKPAASITSKP--ATLTTTSATSKLIH--PDEDISLEERRAQ 363
PA ST+ +T ++A +PAA + P + ++TT + ++ P E
Sbjct: 326 PASVGSTSGPATTPLASAPRPAAPANNPPPPSLMSTTQSRPPWMNSGPSESRPYHGMHGG 385
Query: 364 LPKYQ----RNLPRP--------GQAPIGNPPVGPIGGMMPPQPGIPQQQGMRPP----M 407
P + P P G P+ + P GP M P P P QG PP
Sbjct: 386 GPGGPGGGPHSFPHPLPSLTGGHGGHPMQHNPNGPPPPWMQPPPP-PMNQGPHPPGHHGP 444
Query: 408 PPHGQYGGH----------HQGMPGYLPGAMPPYGQGPPMVPPYQGGPPRPPMGMRPPVM 457
PP QY G HQG G +P PP G PP PP G PP PP G PP
Sbjct: 445 PPMDQYLGSTPVGSGVYRLHQGK-GMMPP--PPMGMMPPPPPPPSGQPPPPPSGPLPPWQ 501
Query: 458 SQ 459
Q
Sbjct: 502 QQ 503
Score = 54.7 bits (130), Expect = 2e-07
Identities = 45/124 (36%), Positives = 55/124 (44%), Gaps = 18/124 (14%)
Query: 116 YDDDDSAASTSFQPQPVQP-QQGYIPPMAQPGLPPVPGAPGM---PPGI-PPLMPGVPPL 170
+ + + +TS + P QQ A PG P + G P M PPG+ PPL PG PP
Sbjct: 525 WQQNTTTTTTSAGTGSIPPWQQQQAAAAASPGAPQMQGNPTMVPLPPGVQPPLPPGAPPP 584
Query: 171 MPGMPPVMPGM---PPGLHHQRKYTQSFCGENIMMPMGGMMPPGPGIPPLMPGMPPGMPP 227
P PP GM PP +F MM MG G+PP GMPP PP
Sbjct: 585 PPPPPPGSAGMMYAPPPPPPPPMDPSNFV---TMMGMG-----VAGMPPF--GMPPAPPP 634
Query: 228 PVPR 231
P P+
Sbjct: 635 PPPQ 638
Score = 53.1 bits (126), Expect = 5e-07
Identities = 46/159 (28%), Positives = 54/159 (33%), Gaps = 22/159 (13%)
Query: 129 PQPVQPQQGYIPPMAQPGLPPVPGAPGMPPGIPPLMPGVPPLMP---------GMPPVMP 179
P P P G PP LPP PP PP + P
Sbjct: 479 PPPPPPPSGQPPPPPSGPLPPWQQQQQQPPPPPPPSSSMASSTPLPWQQNTTTTTTSAGT 538
Query: 180 GMPPGLHHQRKYTQSFCGENIMMPMGGMMPPGPGI-PPLMPGMPPGMPPP---------- 228
G P Q+ + G M M+P PG+ PPL PG PP PPP
Sbjct: 539 GSIPPWQQQQAAAAASPGAPQMQGNPTMVPLPPGVQPPLPPGAPPPPPPPPPGSAGMMYA 598
Query: 229 VPRPGIPPMTQAQAVS--APGILNRPPAPTATVPAPQPP 265
P P PPM + V+ G+ PP P P PP
Sbjct: 599 PPPPPPPPMDPSNFVTMMGMGVAGMPPFGMPPAPPPPPP 637
Score = 52.4 bits (124), Expect = 9e-07
Identities = 51/192 (26%), Positives = 67/192 (34%), Gaps = 43/192 (22%)
Query: 136 QGYIPPMAQPGLPPVPGAPGMPPGIPPLMPGVPPLMPGMPPVMPGMPPG--------LHH 187
+G +PP +PP P P P PP P +PP P PP L
Sbjct: 467 KGMMPPPPMGMMPPPPPPPSGQPPPPPSGP-LPPWQQQQQQPPPPPPPSSSMASSTPLPW 525
Query: 188 QRKYTQSFCGENIMMPMGGMMPP----------GPGIP-----PLMPGMPPGMPPPVPRP 232
Q+ T + G +PP PG P P M +PPG+ PP+P P
Sbjct: 526 QQNTTTTTTSAGT-----GSIPPWQQQQAAAAASPGAPQMQGNPTMVPLPPGVQPPLP-P 579
Query: 233 GIPPMTQAQAVSAPGILNRPPAPTATVPAPQPPVTKPLFPSAGQAQAAVQGPVGTDFKPL 292
G PP + G++ PP P P PP+ F + G P
Sbjct: 580 GAPPPPPPPPPGSAGMMYAPP------PPPPPPMDPSNF-------VTMMGMGVAGMPPF 626
Query: 293 NSTPATTTEPPK 304
PA PP+
Sbjct: 627 GMPPAPPPPPPQ 638
Score = 45.1 bits (105), Expect = 1e-04
Identities = 45/173 (26%), Positives = 62/173 (35%), Gaps = 21/173 (12%)
Query: 308 PAYTQSTASTTSTTNSTAAKPAASITS-----KPATLTTTSATSKLIHPDEDISLEERRA 362
P + T S T+TT T A I S +P + +++ + E A
Sbjct: 264 PWQSSETRSITNTTVCTKCGGAGHIASDCKFQRPGDPQSAQDKARMDKEYLSLMAELGEA 323
Query: 363 QLPKYQRNLPRPGQAPIGNPPVGPIGGMMPPQPGIPQQQGMRPPM---------PPHGQY 413
+P + P P+ + P PP P + RPP P HG +
Sbjct: 324 PVPASVGSTSGPATTPLASAPRPAAPANNPPPPSLMSTTQSRPPWMNSGPSESRPYHGMH 383
Query: 414 GGHHQGMPGYLPGAMP------PYGQGPPMVPPYQGGPPRPPMGMRPPVMSQG 460
GG G PG P + P G G + GPP P M PP M+QG
Sbjct: 384 GGGPGG-PGGGPHSFPHPLPSLTGGHGGHPMQHNPNGPPPPWMQPPPPPMNQG 435
>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo
sapiens]
Length = 1124
Score = 72.8 bits (177), Expect = 6e-13
Identities = 75/331 (22%), Positives = 100/331 (30%), Gaps = 48/331 (14%)
Query: 127 FQPQPVQPQQGYIPPMAQPGLPPVPGAPGMPPGIPPLMPGVPPLMPGMPPVMPGMPPGLH 186
F P P P Q P + P PPV + P PP + P +P PP P M P
Sbjct: 665 FSPPPSPPVQA---PFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSAT 721
Query: 187 HQRKYTQSFCGENIMMPMGGMMPPGPGIPPLMPGMPPGMPPPVPRPGIPPMTQAQAVSAP 246
+ + P +PP P PP P P P +PP+ A + P
Sbjct: 722 PPPQAPPP------------LAAPPLQVPPSPPASPPMSPSATPPPRVPPLLAAPPLQVP 769
Query: 247 GILNRPPAPTATVPAPQPPVTKPLFPSAGQAQAAVQGPVG----TDFKPLNSTPATTTEP 302
PPA P +PP P + QA P F P S P +
Sbjct: 770 ---PSPPASLPMSPLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLAT 826
Query: 303 PKPTFPAYTQSTASTTSTTNSTAAKPAASITSKPATLTTTSATSKLIHPDEDISLEERRA 362
P P P A P + P T A + P D S+ R
Sbjct: 827 PPPQAP--------------PVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRL 872
Query: 363 QLPKYQRNLPRPGQAPIGNPPVGPIGGMMPPQPGIPQQQGMRPPMPPHGQYGGHHQGMPG 422
L P P ++P + G P+ + G+ G G
Sbjct: 873 TLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPE------------ELRGYDSGPEG 920
Query: 423 YLPGAMPPYGQGPPMVPPYQGGPPRPPMGMR 453
+ PP + P P PP+ R
Sbjct: 921 GAAASPPPDAELAACHPAAWSRGPAPPLAFR 951
Score = 65.5 bits (158), Expect = 1e-10
Identities = 87/367 (23%), Positives = 119/367 (32%), Gaps = 47/367 (12%)
Query: 123 ASTSFQPQPVQPQQGYI---PPMAQPGLPPVPGAPGMPPGIPPL-----MPGVPPLMPGM 174
A+TS +Q ++ P Q L PP PPL +P PPL +
Sbjct: 414 ATTSLGSPTLQATHSFLTMSPRQTQASLTSPSRPASTPPDSPPLQAPLSLPASPPLQTSL 473
Query: 175 PP-VMPGMPPGLHHQRKYTQSFCGENIMMPMGGMM-----------------PPGPGIPP 216
P V P P H + S + P+ ++ PP P
Sbjct: 474 SPAVSPLSSPLTIHPLQALSSLASHSPQAPLSSLIMPPLETQSSLAPPSLQTPPASLTTP 533
Query: 217 LMPGMPPGMPPPVPRPGIP---PMTQAQAVSAPGILNRPPAPTATVPAPQPPVTKPLFPS 273
+ +P PPP+ P P + AP L PP+P T P P P
Sbjct: 534 PLENLPSLAPPPLQTASAPLTTPHLETPPCPAPCPLQAPPSPLTTPPPETPSSIATPPPQ 593
Query: 274 AGQAQAA--VQGPVGTDFKPLNSTPATTTEPPKPTFPAYTQSTASTTSTTNSTAAKPAAS 331
A A A+ +QG PL + P PP P + S S A P+
Sbjct: 594 APPALASPPLQGLPSPPLSPLATPPPQA--PPXLALPPLQAPPSPPASPPLSPLATPSPQ 651
Query: 332 ITSKPATLTTTSATSKLIHPDEDISLEERRAQLPKYQRNLPRPGQAP--IGNPPVGPIGG 389
+ A + S P + P + P QAP + PP+
Sbjct: 652 APNALAVHLLQAPFSP--PPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPL----- 704
Query: 390 MMPPQPGIPQQQGMRPPMPPHGQYGGHHQGMPGYLPGAMPPYGQGPPMVPPYQGGPPRPP 449
+PP P P M P P Q P +P + P PPM P P PP
Sbjct: 705 QVPPSP--PASPPMSPSATPPPQAPPPLAAPPLQVPPSPPA---SPPMSPSATPPPRVPP 759
Query: 450 MGMRPPV 456
+ PP+
Sbjct: 760 LLAAPPL 766
Score = 63.5 bits (153), Expect = 4e-10
Identities = 92/344 (26%), Positives = 121/344 (35%), Gaps = 69/344 (20%)
Query: 143 AQPGLPPVPGAPGMPPGIPPLMPGVPPLMPGMPPVMPGMPPGLHHQRKYTQSFCGENIMM 202
A+P PP A +P +PP P PL P PP P PP L +
Sbjct: 314 ARPVPPPDNAATPLPATLPPSPPLATPL-PLAPP-SPSAPPSLQ--------------TL 357
Query: 203 PMGGMMPPGPGIPPLMPGMPPGMPPPVPRPGIPPMTQAQAVSAPGILNRPPAP------- 255
P PP PP M P PP + IPP+ ++++P L PP+P
Sbjct: 358 PSPPATPPSQA-PPSMTTPPMQAPPSLQT--IPPIQVPHSLTSPS-LQAPPSPLALSSLQ 413
Query: 256 -TATVPAPQPPVTKP-LFPSAGQAQAAVQGPVGTDFKPLNSTPATTTEPPKPTFPAYTQS 313
T ++ +P T L S Q QA++ P S PA+T P P
Sbjct: 414 ATTSLGSPTLQATHSFLTMSPRQTQASLTSP---------SRPAST----PPDSPPLQAP 460
Query: 314 TASTTSTTNSTAAKPAASITSKPATLTTTSATSKLIHPDEDISLEERRAQLPKYQRNLPR 373
+ S T+ PA S S P T+ A S L L + Q +L
Sbjct: 461 LSLPASPPLQTSLSPAVSPLSSPLTIHPLQALSSLASHSPQAPLSSLIMPPLETQSSLAP 520
Query: 374 PG----QAPIGNPPVGPIGGMMPPQPGIPQQQGMRPPMPPHGQYGGHHQGMPGYLPG--- 426
P A + PP+ + + PP P Q P PH + P P
Sbjct: 521 PSLQTPPASLTTPPLENLPSLAPP----PLQTASAPLTTPHLETPPCPAPCPLQAPPSPL 576
Query: 427 -----------AMPPYGQGPPMV--PPYQG--GPPRPPMGMRPP 455
A PP Q PP + PP QG PP P+ PP
Sbjct: 577 TTPPPETPSSIATPP-PQAPPALASPPLQGLPSPPLSPLATPPP 619
Score = 60.8 bits (146), Expect = 2e-09
Identities = 89/337 (26%), Positives = 119/337 (35%), Gaps = 43/337 (12%)
Query: 129 PQPVQPQQGYIPPMAQPGLPPVPGAPGMPPGIPPLMPGVPPLMPGMPPVMPGMPPGLHHQ 188
P P+ P P A P L +P P PP P PP+ PP + +PP
Sbjct: 340 PLPLAPPS----PSAPPSLQTLPSPPATPPSQAPPSMTTPPMQ--APPSLQTIPP----- 388
Query: 189 RKYTQSFCGENIMMPMGGMMPPGPGIPPLMPGMPPGMPPPVPRPGIPPMTQAQAVSAPGI 248
+ S ++ P P + L G P M+ Q ++
Sbjct: 389 IQVPHSLTSPSLQAP-----PSPLALSSLQATTSLGSPTLQATHSFLTMSPRQTQAS--- 440
Query: 249 LNRPPAPTATVPAPQPPVTKPL-FPSAGQAQAAVQGPVGTDFKPLNSTPATTTEPPKPTF 307
L P P +T P PP+ PL P++ Q ++ V PL P
Sbjct: 441 LTSPSRPAST-PPDSPPLQAPLSLPASPPLQTSLSPAVSPLSSPLTIHPLQALSSLASHS 499
Query: 308 P-AYTQSTASTTSTTNSTAAKPAASITSKPATLTTTSATS--KLIHPDEDISLEERRAQL 364
P A S T S+ A P S+ + PA+LTT + L P L+ A L
Sbjct: 500 PQAPLSSLIMPPLETQSSLAPP--SLQTPPASLTTPPLENLPSLAPP----PLQTASAPL 553
Query: 365 -PKYQRNLPRPGQAPIGNPPVGPIGGMMPPQPGIPQQQGMRPPMPPHGQYGGHHQGMPG- 422
+ P P P+ PP + P P P PP P QG+P
Sbjct: 554 TTPHLETPPCPAPCPLQAPP----SPLTTPPPETPSSIATPPPQAPPALASPPLQGLPSP 609
Query: 423 -YLPGAMPPYGQGPP--MVPPYQGGPPRPPMGMRPPV 456
P A PP Q PP +PP Q PP PP PP+
Sbjct: 610 PLSPLATPP-PQAPPXLALPPLQ-APPSPPAS--PPL 642
Score = 59.7 bits (143), Expect = 5e-09
Identities = 85/330 (25%), Positives = 108/330 (32%), Gaps = 58/330 (17%)
Query: 131 PVQPQQGYIPPMAQPG-----LPPVPGAPGMPPGIPPLMPGVPPLM------PGMPPVMP 179
P++ Q PP Q PP+ P + P PPL PL P P P
Sbjct: 511 PLETQSSLAPPSLQTPPASLTTPPLENLPSLAP--PPLQTASAPLTTPHLETPPCPAPCP 568
Query: 180 --GMPPGLHHQRKYTQSFCGENIMMPMGGMMPPGPGIPPLMPGMP-PGMPPPVPRPGIPP 236
P L T S + P P PP + P G+P P P P
Sbjct: 569 LQAPPSPLTTPPPETPS-----------SIATPPPQAPPALASPPLQGLPSPPLSPLATP 617
Query: 237 MTQAQAVSAPGILNRPPAPTATVPAPQPPVTKPLFPSAGQAQAAVQGPVGTDFKPLNSTP 296
QA A L PP+P A+ P P P+A A +Q P F P S P
Sbjct: 618 PPQAPPXLALPPLQAPPSPPASPPLSPLATPSPQAPNA-LAVHLLQAP----FSPPPSPP 672
Query: 297 ATTTEPPKPTFPAYTQSTASTTSTTNSTAAKPAASITSKPATLTTTSATSKLIHPDEDIS 356
P P P + S + S AA P S PA + + S P
Sbjct: 673 VQAPFSP-PASPPVSPSATPPSQAPPSLAAPPLQVPPSPPA--SPPMSPSATPPPQAPPP 729
Query: 357 LEERRAQLPKYQRNLPRPGQAPIGNPPVGPIGGMMPPQPGIPQQQGMRPPMPPHGQYGGH 416
L Q+P +P +PP+ P P P + ++ P P
Sbjct: 730 LAAPPLQVP----------PSPPASPPMSPSATPPPRVPPLLAAPPLQVPPSP------- 772
Query: 417 HQGMPGYLPGAMPPYGQGPPMVPPYQGGPP 446
P LP M P + PP PP PP
Sbjct: 773 ----PASLP--MSPLAKPPPQAPPALATPP 796
Score = 59.3 bits (142), Expect = 7e-09
Identities = 81/343 (23%), Positives = 110/343 (32%), Gaps = 49/343 (14%)
Query: 121 SAASTSFQPQPVQPQQGYIPPMAQPGLPPVPGAPGMPPGIPPLMPGVPPLMPGMPPVMPG 180
S A S P+Q +PP + P PP+ + PP PP + P +P PP P
Sbjct: 693 SQAPPSLAAPPLQ-----VPP-SPPASPPMSPSATPPPQAPPPLAAPPLQVPPSPPASP- 745
Query: 181 MPPGLHHQRKYTQSFCGENIMMPMGGMMPPGPGIPPLMPGMPPGMPPPVPRPGIPPMTQA 240
PM P P +PPL+ PP PP P +P A
Sbjct: 746 ----------------------PMSPSATPPPRVPPLL-AAPPLQVPPSPPASLPMSPLA 782
Query: 241 Q-AVSAPGILNRPPAPTATVPAPQPPVTKPLFPSAGQAQAAVQGPVGTDFKPLNSTPATT 299
+ AP L PP P P P PSA + + P P+ + P
Sbjct: 783 KPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATP-PPQAPPVLAAPLLQ 841
Query: 300 TEPPKPTFPAYTQSTASTTSTTNSTAAKP--AASITSKPATLTTTSATSKLIHPD---ED 354
P P P T +++ + P ++ P + S +S L PD
Sbjct: 842 VPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHS 901
Query: 355 ISLEERRAQLPKYQRNLPRPGQAPIGNPPVGPIGGMMPPQPGIPQQQGMRPPMPPHGQYG 414
S +L Y G A PP + P +G PP+ G G
Sbjct: 902 SSATSTPEELRGYDSG--PEGGAAASPPPDAELAACHP----AAWSRGPAPPLAFRGAPG 955
Query: 415 GHHQGMPGYLPGAMPPY-----GQGPPMVPPYQGG-PPRPPMG 451
P PG+ +GP P G P P G
Sbjct: 956 APLPWPPATGPGSADGLCTIYETEGPESATPAPGALDPGPSPG 998
Score = 42.0 bits (97), Expect = 0.001
Identities = 66/280 (23%), Positives = 95/280 (33%), Gaps = 47/280 (16%)
Query: 210 PGPGIPPLMPGMPPGMPPPVPRPGIPPMTQA--QAVSAPGILNRPPAPT-------ATVP 260
P P L+ PPG P P PP+T A + + A G + R P AT+P
Sbjct: 17 PAARAPGLLTPRPPGSPRPP-----PPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIP 71
Query: 261 APQP--------------PVTKPLFPSAGQAQAAVQGPVGTDFKPLNST-PATTTEPPKP 305
P P ++P P++G+ + A T P++S A+ T P P
Sbjct: 72 ESAPRAGPTRSAGTSSRNPASRP--PASGRGERAPPAK-NTSPGPVSSPGRASGTTRPGP 128
Query: 306 TFPAYTQSTASTTSTTNSTAAKPAASITSKPATLTTTSATSKLIHPDEDISLEERRAQLP 365
+ +A T P S S A T+ T P RR++
Sbjct: 129 LGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPT-----PGTPSPAMARRSRAA 183
Query: 366 KYQRNLPRPGQAPIGNPPV-GP---IGGMMPPQPGIPQQQGMRPPMPPHGQYGGHHQGM- 420
+ LPRP + PP GP + P R P G + +
Sbjct: 184 GTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLS 243
Query: 421 ----PGYLPGAMPPYGQGPPMVPPYQGGP-PRPPMGMRPP 455
P P P +G P P + P P+ +RPP
Sbjct: 244 SSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPP 283
Score = 40.8 bits (94), Expect = 0.003
Identities = 79/326 (24%), Positives = 104/326 (31%), Gaps = 41/326 (12%)
Query: 168 PPLMPGMPPVMPGMPPGLHHQRKYTQSFCGENIMMPM----GGMMPPGPGIPPLMPGMPP 223
P L+ PP P PP + G P+ GG+ G IP P P
Sbjct: 22 PGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGI--GGATIPESAPRAGP 79
Query: 224 GMPPPVP--RPGIPPMTQAQAVSAPGILNRPPAPTAT------VPAPQPPVTKPLFPSAG 275
P P + AP N P P ++ P P K L SA
Sbjct: 80 TRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAE 139
Query: 276 QAQAAVQGPVGTDFKPLNSTPATTTEPPKPTFPAYTQSTASTTSTTNSTAAKPAASITSK 335
+ A + L++ T P P P+ + S + T +PA S +
Sbjct: 140 ETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPR 199
Query: 336 PATL-TTTSATSKLIHPDEDISLEERRAQLPKYQRNLPRPGQ-------APIGNPP-VGP 386
P T S +S H + S RR P L RP P+ +P GP
Sbjct: 200 PPTEGPRKSVSSASEHSTTEPSPAARRR--PSAGGGLQRPASRSLSSSATPLSSPARSGP 257
Query: 387 IGGMMPPQPGIPQQ------QGMRPP-MPPHGQYGGHHQGMPGYLPGAMP-PYGQGPPMV 438
P P P Q Q +RPP + P + G P A P P G V
Sbjct: 258 SARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSGTKARPV 317
Query: 439 PPYQGG--------PPRPPMGMRPPV 456
PP PP PP+ P+
Sbjct: 318 PPPDNAATPLPATLPPSPPLATPLPL 343
>gi|116284398 WAS/WASL interacting protein family, member 1 [Homo
sapiens]
Length = 503
Score = 72.8 bits (177), Expect = 6e-13
Identities = 89/342 (26%), Positives = 111/342 (32%), Gaps = 93/342 (27%)
Query: 131 PVQPQQGYIPPMAQPGLPPVPGAPGMPPGIPPLMPGVP------PLMPGMPPV------- 177
P +PQ+ +PP P P P IPP +P P P G PPV
Sbjct: 161 PPEPQRNRMPP-------PRPDVGSKPDSIPPPVPSTPRPIQSSPHNRGSPPVPGGPRQP 213
Query: 178 MPGMPPGLHHQRKYTQSFCGENIMMPMGGMMPPG--PGIPPLMPGMPPGMPPPVPRPGIP 235
PG P + T G P+ P P +PP PPP P P
Sbjct: 214 SPGPTPPPFPGNRGTALGGGSIRQSPLSSSSPFSNRPPLPPTPSRALDDKPPPPPPP--- 270
Query: 236 PMTQAQAVSAPGILNRPPAPTATVPAPQPPVTKPLFPSAGQAQAAVQGPVGTDFKPLNST 295
+ NRP VP P P KP PS + A+ Q P
Sbjct: 271 ------------VGNRPSIHREAVPPPPPQNNKPPVPSTPRPSASSQAP----------- 307
Query: 296 PATTTEPPKPTFPAYTQSTASTTSTTNSTAAKPAASITSKPATLTTTSATSKLIHPDEDI 355
PP P+ P P L +S+ + DE
Sbjct: 308 ----PPPPPPSRPG--------------------------PPPLPPSSSGN-----DETP 332
Query: 356 SLEERRAQLPKYQRNLPRPGQAPIGNPPVGPIGGMMPPQPGIPQQQGMRPPMPPHGQYGG 415
L +R L LP PG++ G P P PP P + G PP PP + G
Sbjct: 333 RLPQRNLSLSSSTPPLPSPGRS--GPLPPPPSERPPPPVRDPPGRSGPLPPPPPVSRNGS 390
Query: 416 HHQGMPG--YLPGA----MPPYGQGPPMVP--PYQGGPPRPP 449
+ +P LP P G PP+ P P G PP PP
Sbjct: 391 TSRALPATPQLPSRSGVDSPRSGPRPPLPPDRPSAGAPPPPP 432
Score = 62.4 bits (150), Expect = 8e-10
Identities = 67/262 (25%), Positives = 97/262 (37%), Gaps = 43/262 (16%)
Query: 211 GPGIPPLMPGMPPGMPPPVPRPGIPPMTQAQ-AVSAPGILNRPPAPTAT-VPAPQPPVTK 268
G PPL+P PG +P PP + V +PG + PP P +P P+P V
Sbjct: 122 GGSRPPLLP---PGGRSTSAKPFSPPSGPGRFPVPSPGHRSGPPEPQRNRMPPPRPDV-- 176
Query: 269 PLFPSAGQAQAAVQGPVGTDFKPLNSTPATTTEPPKPTFPAY-TQSTASTTSTTNSTAAK 327
G ++ PV + +P+ S+P PP P P + N A
Sbjct: 177 ------GSKPDSIPPPVPSTPRPIQSSPHNRGSPPVPGGPRQPSPGPTPPPFPGNRGTAL 230
Query: 328 PAASITSKPATLTTTSATSKLIHPDEDISLEERRAQLPKYQRNLPRPGQAPIGNPPVGPI 387
SI P + ++ + + P +L+++ P P P+GN P
Sbjct: 231 GGGSIRQSPLSSSSPFSNRPPLPPTPSRALDDK-----------PPPPPPPVGNRPSIHR 279
Query: 388 GGMMPPQPGIPQQQGMRPPMPPHGQYGGHHQGMPGYLPGAMPPYGQGPPMVPPYQGG--- 444
+ PP P Q +PP+P + Q P PP GPP +PP G
Sbjct: 280 EAVPPPPP-----QNNKPPVPSTPRPSASSQAP----PPPPPPSRPGPPPLPPSSSGNDE 330
Query: 445 PPRPPM------GMRPPVMSQG 460
PR P PP+ S G
Sbjct: 331 TPRLPQRNLSLSSSTPPLPSPG 352
Score = 55.1 bits (131), Expect = 1e-07
Identities = 62/207 (29%), Positives = 73/207 (35%), Gaps = 40/207 (19%)
Query: 140 PPMAQPGLPPVPGAPGMPPGIPPLMPGVPPLMPGMPPVMPGM-----PPGLHHQRKYTQS 194
PP Q PPVP P P PP PG PP+ P P L QR + S
Sbjct: 284 PPPPQNNKPPVPSTPRPSASSQAPPPPPPPSRPGPPPLPPSSSGNDETPRL-PQRNLSLS 342
Query: 195 FCGENIMMP-MGGMMPPGPGIPPLMPGM-PPGM------PPPVPR--------PGIPPMT 238
+ P G +PP P P P PPG PPPV R P P +
Sbjct: 343 SSTPPLPSPGRSGPLPPPPSERPPPPVRDPPGRSGPLPPPPPVSRNGSTSRALPATPQLP 402
Query: 239 QAQAVSAPGILNRPPAPTATVPAPQPPVTKPLFPSAGQAQAAVQGPVGTD------FKPL 292
V +P RPP P A PP P PS P + F P+
Sbjct: 403 SRSGVDSPRSGPRPPLPPDRPSAGAPP---PPPPSTSIRNGFQDSPCEDEWESRFYFHPI 459
Query: 293 NSTPATTTEPPKPTFPAYTQSTASTTS 319
+ P PP+P Y Q+T S S
Sbjct: 460 SDLP-----PPEP----YVQTTKSYPS 477
Score = 38.1 bits (87), Expect = 0.017
Identities = 25/89 (28%), Positives = 35/89 (39%), Gaps = 1/89 (1%)
Query: 361 RAQLPKYQRNLPRPGQAPIGNPPVGPIGGMMPP-QPGIPQQQGMRPPMPPHGQYGGHHQG 419
+A +PK + R + PP+ P GG +P P R P+P G G +
Sbjct: 105 QAGMPKLRSTANRDNDSGGSRPPLLPPGGRSTSAKPFSPPSGPGRFPVPSPGHRSGPPEP 164
Query: 420 MPGYLPGAMPPYGQGPPMVPPYQGGPPRP 448
+P P G P +PP PRP
Sbjct: 165 QRNRMPPPRPDVGSKPDSIPPPVPSTPRP 193
Score = 35.0 bits (79), Expect = 0.14
Identities = 38/175 (21%), Positives = 61/175 (34%), Gaps = 38/175 (21%)
Query: 111 DDSDEYDDDDSAASTSFQPQPVQPQQGYI-PPMAQPGLPPVPGAPGMPPGIPPLMPGVPP 169
D++ + + S+S P P + G + PP ++ PPV PG +PP
Sbjct: 329 DETPRLPQRNLSLSSSTPPLPSPGRSGPLPPPPSERPPPPVRDPPGRSGPLPP------- 381
Query: 170 LMPGMPPVMPGMPPGLHHQRKYTQSFCGENIMMPMGGMMPPGPGIPPLMPGMPPGMPPPV 229
PP + +++ +P +P G+ G P +PP
Sbjct: 382 ------------PPPVSRNGSTSRA-------LPATPQLPSRSGVDSPRSGPRPPLPPDR 422
Query: 230 PRPGIPPMTQAQAVSAPGILNRPPA----------PTATVPAPQPPV-TKPLFPS 273
P G PP G + P P + +P P+P V T +PS
Sbjct: 423 PSAGAPPPPPPSTSIRNGFQDSPCEDEWESRFYFHPISDLPPPEPYVQTTKSYPS 477
>gi|38373695 WAS/WASL interacting protein family, member 1 [Homo
sapiens]
Length = 503
Score = 72.8 bits (177), Expect = 6e-13
Identities = 89/342 (26%), Positives = 111/342 (32%), Gaps = 93/342 (27%)
Query: 131 PVQPQQGYIPPMAQPGLPPVPGAPGMPPGIPPLMPGVP------PLMPGMPPV------- 177
P +PQ+ +PP P P P IPP +P P P G PPV
Sbjct: 161 PPEPQRNRMPP-------PRPDVGSKPDSIPPPVPSTPRPIQSSPHNRGSPPVPGGPRQP 213
Query: 178 MPGMPPGLHHQRKYTQSFCGENIMMPMGGMMPPG--PGIPPLMPGMPPGMPPPVPRPGIP 235
PG P + T G P+ P P +PP PPP P P
Sbjct: 214 SPGPTPPPFPGNRGTALGGGSIRQSPLSSSSPFSNRPPLPPTPSRALDDKPPPPPPP--- 270
Query: 236 PMTQAQAVSAPGILNRPPAPTATVPAPQPPVTKPLFPSAGQAQAAVQGPVGTDFKPLNST 295
+ NRP VP P P KP PS + A+ Q P
Sbjct: 271 ------------VGNRPSIHREAVPPPPPQNNKPPVPSTPRPSASSQAP----------- 307
Query: 296 PATTTEPPKPTFPAYTQSTASTTSTTNSTAAKPAASITSKPATLTTTSATSKLIHPDEDI 355
PP P+ P P L +S+ + DE
Sbjct: 308 ----PPPPPPSRPG--------------------------PPPLPPSSSGN-----DETP 332
Query: 356 SLEERRAQLPKYQRNLPRPGQAPIGNPPVGPIGGMMPPQPGIPQQQGMRPPMPPHGQYGG 415
L +R L LP PG++ G P P PP P + G PP PP + G
Sbjct: 333 RLPQRNLSLSSSTPPLPSPGRS--GPLPPPPSERPPPPVRDPPGRSGPLPPPPPVSRNGS 390
Query: 416 HHQGMPG--YLPGA----MPPYGQGPPMVP--PYQGGPPRPP 449
+ +P LP P G PP+ P P G PP PP
Sbjct: 391 TSRALPATPQLPSRSGVDSPRSGPRPPLPPDRPSAGAPPPPP 432
Score = 62.4 bits (150), Expect = 8e-10
Identities = 67/262 (25%), Positives = 97/262 (37%), Gaps = 43/262 (16%)
Query: 211 GPGIPPLMPGMPPGMPPPVPRPGIPPMTQAQ-AVSAPGILNRPPAPTAT-VPAPQPPVTK 268
G PPL+P PG +P PP + V +PG + PP P +P P+P V
Sbjct: 122 GGSRPPLLP---PGGRSTSAKPFSPPSGPGRFPVPSPGHRSGPPEPQRNRMPPPRPDV-- 176
Query: 269 PLFPSAGQAQAAVQGPVGTDFKPLNSTPATTTEPPKPTFPAY-TQSTASTTSTTNSTAAK 327
G ++ PV + +P+ S+P PP P P + N A
Sbjct: 177 ------GSKPDSIPPPVPSTPRPIQSSPHNRGSPPVPGGPRQPSPGPTPPPFPGNRGTAL 230
Query: 328 PAASITSKPATLTTTSATSKLIHPDEDISLEERRAQLPKYQRNLPRPGQAPIGNPPVGPI 387
SI P + ++ + + P +L+++ P P P+GN P
Sbjct: 231 GGGSIRQSPLSSSSPFSNRPPLPPTPSRALDDK-----------PPPPPPPVGNRPSIHR 279
Query: 388 GGMMPPQPGIPQQQGMRPPMPPHGQYGGHHQGMPGYLPGAMPPYGQGPPMVPPYQGG--- 444
+ PP P Q +PP+P + Q P PP GPP +PP G
Sbjct: 280 EAVPPPPP-----QNNKPPVPSTPRPSASSQAP----PPPPPPSRPGPPPLPPSSSGNDE 330
Query: 445 PPRPPM------GMRPPVMSQG 460
PR P PP+ S G
Sbjct: 331 TPRLPQRNLSLSSSTPPLPSPG 352
Score = 55.1 bits (131), Expect = 1e-07
Identities = 62/207 (29%), Positives = 73/207 (35%), Gaps = 40/207 (19%)
Query: 140 PPMAQPGLPPVPGAPGMPPGIPPLMPGVPPLMPGMPPVMPGM-----PPGLHHQRKYTQS 194
PP Q PPVP P P PP PG PP+ P P L QR + S
Sbjct: 284 PPPPQNNKPPVPSTPRPSASSQAPPPPPPPSRPGPPPLPPSSSGNDETPRL-PQRNLSLS 342
Query: 195 FCGENIMMP-MGGMMPPGPGIPPLMPGM-PPGM------PPPVPR--------PGIPPMT 238
+ P G +PP P P P PPG PPPV R P P +
Sbjct: 343 SSTPPLPSPGRSGPLPPPPSERPPPPVRDPPGRSGPLPPPPPVSRNGSTSRALPATPQLP 402
Query: 239 QAQAVSAPGILNRPPAPTATVPAPQPPVTKPLFPSAGQAQAAVQGPVGTD------FKPL 292
V +P RPP P A PP P PS P + F P+
Sbjct: 403 SRSGVDSPRSGPRPPLPPDRPSAGAPP---PPPPSTSIRNGFQDSPCEDEWESRFYFHPI 459
Query: 293 NSTPATTTEPPKPTFPAYTQSTASTTS 319
+ P PP+P Y Q+T S S
Sbjct: 460 SDLP-----PPEP----YVQTTKSYPS 477
Score = 38.1 bits (87), Expect = 0.017
Identities = 25/89 (28%), Positives = 35/89 (39%), Gaps = 1/89 (1%)
Query: 361 RAQLPKYQRNLPRPGQAPIGNPPVGPIGGMMPP-QPGIPQQQGMRPPMPPHGQYGGHHQG 419
+A +PK + R + PP+ P GG +P P R P+P G G +
Sbjct: 105 QAGMPKLRSTANRDNDSGGSRPPLLPPGGRSTSAKPFSPPSGPGRFPVPSPGHRSGPPEP 164
Query: 420 MPGYLPGAMPPYGQGPPMVPPYQGGPPRP 448
+P P G P +PP PRP
Sbjct: 165 QRNRMPPPRPDVGSKPDSIPPPVPSTPRP 193
Score = 35.0 bits (79), Expect = 0.14
Identities = 38/175 (21%), Positives = 61/175 (34%), Gaps = 38/175 (21%)
Query: 111 DDSDEYDDDDSAASTSFQPQPVQPQQGYI-PPMAQPGLPPVPGAPGMPPGIPPLMPGVPP 169
D++ + + S+S P P + G + PP ++ PPV PG +PP
Sbjct: 329 DETPRLPQRNLSLSSSTPPLPSPGRSGPLPPPPSERPPPPVRDPPGRSGPLPP------- 381
Query: 170 LMPGMPPVMPGMPPGLHHQRKYTQSFCGENIMMPMGGMMPPGPGIPPLMPGMPPGMPPPV 229
PP + +++ +P +P G+ G P +PP
Sbjct: 382 ------------PPPVSRNGSTSRA-------LPATPQLPSRSGVDSPRSGPRPPLPPDR 422
Query: 230 PRPGIPPMTQAQAVSAPGILNRPPA----------PTATVPAPQPPV-TKPLFPS 273
P G PP G + P P + +P P+P V T +PS
Sbjct: 423 PSAGAPPPPPPSTSIRNGFQDSPCEDEWESRFYFHPISDLPPPEPYVQTTKSYPS 477
>gi|7662046 myeloid/lymphoid or mixed-lineage leukemia 4 [Homo
sapiens]
Length = 2715
Score = 72.4 bits (176), Expect = 8e-13
Identities = 92/370 (24%), Positives = 138/370 (37%), Gaps = 79/370 (21%)
Query: 98 EQKTQ-ESQKKKQQDDSDEYDDDDSAASTSFQPQPVQPQQGYIPPMAQPGLPPVPGAPGM 156
EQK E ++KK++++ D+ ++ + + + P ++ + LPP
Sbjct: 358 EQKLDDEEEEKKEEEEKDKEGEEKEERAVAEEMMPAAEKE-------EAKLPP------- 403
Query: 157 PPGIPPLMPGVPPLMPGMPPVMPGMPPGLHHQRKYTQSFCGENIMMPMGGMMPPGPGIPP 216
PPL P P P +PP PP L PP P
Sbjct: 404 ----PPLTPPAPSPPPPLPPPSTSPPPPL----------------------CPPPP---- 433
Query: 217 LMPGMPPGMPPPVPRPGIPPMTQAQAVSAPGILNRPPAPTATVPAPQPPVTKPLFPSAGQ 276
PP PPP+P P PP + Q S P ++ PA T + +PP+T +
Sbjct: 434 -----PPVSPPPLPSPPPPPAQEEQEESPPPVV---PA-TCSRKRGRPPLTPS---QRAE 481
Query: 277 AQAAVQGPVGTDFKPLNSTPATTTEPPKPTFPAYTQSTASTTSTTNSTA-AKPAASITSK 335
+AA GP GT P TP+T T P P T + STT N P S S
Sbjct: 482 REAARAGPEGTS--PPTPTPSTATGGPPEDSP--TVAPKSTTFLKNIRQFIMPVVSARSS 537
Query: 336 PATLTTTSATSKLIHPDEDISLEERRAQLPKYQRNLPRPGQ-APIGNPPVGPIGGMMPPQ 394
T + P + +E P + P P + AP+ +PP P PP
Sbjct: 538 RVIKTPRRFMDE--DPPKPPKVEVSPVLRPPITTSPPVPQEPAPVPSPPRAPT----PPS 591
Query: 395 PGIPQQQGMRPPM-PPHGQYGGHHQGMPGYLPGAMPPYGQGPPMVPPYQGGPPRPPMGMR 453
+P + R + P ++ + +P PP PP PP PP P R
Sbjct: 592 TPVPLPEKRRSILREPTFRWTSLTRELP-------PPPPAPPP--PPAPSPPPAPATSSR 642
Query: 454 PPVMSQGGRY 463
P++ + ++
Sbjct: 643 RPLLLRAPQF 652
Score = 62.4 bits (150), Expect = 8e-10
Identities = 90/382 (23%), Positives = 123/382 (32%), Gaps = 68/382 (17%)
Query: 87 EKDMDERRRLLEQKTQESQKKKQQDDSDEYDDDDSAASTSFQPQPVQPQQGYIPPMAQPG 146
E+ +D+ E+K +E +K K+ ++ +E + + + + P PP P
Sbjct: 358 EQKLDDEE---EEKKEEEEKDKEGEEKEERAVAEEMMPAAEKEEAKLPPPPLTPPAPSPP 414
Query: 147 LPPVPGAPGMPPGIPPLMPGVPPLMPGMPPVMPGMPPGLHHQRKYTQSFCGENIMMPMGG 206
PP+P PP PPL P PP P PP +P PP
Sbjct: 415 -PPLPPPSTSPP--PPLCPPPPP--PVSPPPLPSPPP----------------------- 446
Query: 207 MMPPGPGIPPLMPGMPPGMPPPVP-----RPGIPPMTQAQ-----AVSAPGILNRPPAPT 256
PP PP VP + G PP+T +Q A A PP PT
Sbjct: 447 --------PPAQEEQEESPPPVVPATCSRKRGRPPLTPSQRAEREAARAGPEGTSPPTPT 498
Query: 257 ATVPAPQPPVTKPLFPSAG-----QAQAAVQGPVGTDFKPLNSTPA--TTTEPPKPTFPA 309
+ PP P + + V + TP +PPKP
Sbjct: 499 PSTATGGPPEDSPTVAPKSTTFLKNIRQFIMPVVSARSSRVIKTPRRFMDEDPPKPP-KV 557
Query: 310 YTQSTASTTSTTNSTAAKPAASITSKPATLTTTSATSKLIHPDEDISLEERRAQLPKYQR 369
TT+ + A + S P T S L I L E + R
Sbjct: 558 EVSPVLRPPITTSPPVPQEPAPVPSPPRAPTPPSTPVPLPEKRRSI-LREPTFRWTSLTR 616
Query: 370 NLPRPGQAPIGNPPVGPIGGMMPPQPGIPQQQGMRPPMPPHGQYGGHHQGMPGYLPGAMP 429
LP P AP P P PP P ++ + P H + L P
Sbjct: 617 ELPPPPPAPPPPPAPSP-----PPAPATSSRRPLLLRAPQFTPSEAHLKIYESVL--TPP 669
Query: 430 PYG--QGP-PMVPPYQGGPPRP 448
P G + P P PP P P
Sbjct: 670 PLGAPEAPEPEPPPADDSPAEP 691
Score = 38.5 bits (88), Expect = 0.013
Identities = 49/180 (27%), Positives = 65/180 (36%), Gaps = 29/180 (16%)
Query: 133 QPQQGYIPPMAQPGLPPVPGAPGMPPGIPPLMPGVPPLMPGMPPVMPGMPPGLHHQRKYT 192
+P G PP+ L VPGAP I L P + P PP P
Sbjct: 1813 EPPGGEDPPLDTDVL--VPGAPERHSPIQNLDPPLRPDSGSAPPPAP------------- 1857
Query: 193 QSFCGENIMMP-MGGMMPPGPGI---PPLMPGMPPGMPPPVPRPGIPPMTQAQAVSAPGI 248
+SF G I +P P G+ P PG P + +P G P AP
Sbjct: 1858 RSFSGARIKVPNYSPSRRPLGGVSFGPLPSPGSPSSLTHHIPTVGDPDF------PAPPR 1911
Query: 249 LNRPPAPTATVPAPQPPVTKPLFPSAGQAQAAVQGPVGTDFKPLN---STPATTTEPPKP 305
+R P+P A P P + PL ++ Q + V T P + + P PP P
Sbjct: 1912 RSRRPSPLAPRPPPSRWASPPL-KTSPQLRVPPPTSVVTALTPTSGELAPPGPAPSPPPP 1970
Score = 34.3 bits (77), Expect = 0.25
Identities = 38/150 (25%), Positives = 49/150 (32%), Gaps = 37/150 (24%)
Query: 147 LPPVPGAPGMPPGIPPLMPGVPPLMPGMPPVM--PGMPPGLHHQRKYTQSFCGENIMMPM 204
LPP P AP PP P P P P ++ P P H + Y E+++ P
Sbjct: 618 LPPPPPAPPPPPAPSP--PPAPATSSRRPLLLRAPQFTPSEAHLKIY------ESVLTP- 668
Query: 205 GGMMPPGPGIPPLMPGMPPGMPPPVPRPGIPPMTQAQAVSAPGILNR---------PPAP 255
PP P P P PP + A P + R P
Sbjct: 669 -----------------PPLGAPEAPEPEPPPADDSPAEPEPRAVGRTNHLSLPRFAPVV 711
Query: 256 TATVPAPQPPVTKPLFPSAGQAQAAVQGPV 285
T V A P P + Q QA + P+
Sbjct: 712 TTPVKAEVSPHGAPALSNGPQTQAQLLQPL 741
Score = 34.3 bits (77), Expect = 0.25
Identities = 40/144 (27%), Positives = 52/144 (36%), Gaps = 25/144 (17%)
Query: 133 QPQQGYIPPMAQPG--LPPVPGAPGMPPGIPPLMPGVPPLMPGMPPVMPGMPPGLHHQRK 190
QP QG A P +PGAPG+ + L P P P ++ K
Sbjct: 2147 QPSQGLTASPADPTRTFAWLPGAPGVR--VLSLGPAPEPPKPATSKIIL--------VNK 2196
Query: 191 YTQSFCGENIMMPMGGMMPPGPGIPPLMPGMPPGMP-----PPVPRPGIPPMTQAQAVSA 245
Q F M G +PP PPL P + P P PP P G+ P+ +
Sbjct: 2197 LGQVFVK---MAGEGEPVPPPVKQPPLPPTISPTAPTSWTLPPGPLLGVLPVVGVVRPAP 2253
Query: 246 PGILNRPPAPTATVPAPQPPVTKP 269
P PP P T+ P + P
Sbjct: 2254 P-----PPPPPLTLVLSSGPASPP 2272
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.314 0.136 0.437
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 29,550,261
Number of Sequences: 37866
Number of extensions: 2361066
Number of successful extensions: 48829
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 678
Number of HSP's successfully gapped in prelim test: 1867
Number of HSP's that attempted gapping in prelim test: 14903
Number of HSP's gapped (non-prelim): 16494
length of query: 463
length of database: 18,247,518
effective HSP length: 106
effective length of query: 357
effective length of database: 14,233,722
effective search space: 5081438754
effective search space used: 5081438754
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.