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Search of human proteins with 73532778
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|73532778 casein kinase 1, gamma 3 isoform 1 [Homo sapiens]
(447 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|73532778 casein kinase 1, gamma 3 isoform 1 [Homo sapiens] 924 0.0
gi|113462010 casein kinase 1, gamma 3 isoform 4 [Homo sapiens] 914 0.0
gi|113462008 casein kinase 1, gamma 3 isoform 3 [Homo sapiens] 839 0.0
gi|73532780 casein kinase 1, gamma 3 isoform 2 [Homo sapiens] 830 0.0
gi|153791733 casein kinase 1, gamma 2 [Homo sapiens] 686 0.0
gi|98986450 casein kinase 1, gamma 1 [Homo sapiens] 684 0.0
gi|23199991 casein kinase 1 epsilon [Homo sapiens] 367 e-102
gi|4503093 casein kinase 1 epsilon [Homo sapiens] 367 e-102
gi|20544145 casein kinase 1, delta isoform 2 [Homo sapiens] 360 1e-99
gi|20149530 casein kinase 1, delta isoform 1 [Homo sapiens] 360 1e-99
gi|68303572 casein kinase 1, alpha 1 isoform 2 [Homo sapiens] 332 5e-91
gi|68303575 casein kinase 1, alpha 1 isoform 1 [Homo sapiens] 323 3e-88
gi|21624639 casein kinase 1, alpha 1-like [Homo sapiens] 321 1e-87
gi|58761548 tau tubulin kinase 1 [Homo sapiens] 154 1e-37
gi|116812624 tau tubulin kinase 2 [Homo sapiens] 148 1e-35
gi|4507903 vaccinia related kinase 1 [Homo sapiens] 117 3e-26
gi|194440713 vaccinia related kinase 2 isoform 3 [Homo sapiens] 108 1e-23
gi|194440711 vaccinia related kinase 2 isoform 2 [Homo sapiens] 108 1e-23
gi|194440709 vaccinia related kinase 2 isoform 1 [Homo sapiens] 108 1e-23
gi|194440707 vaccinia related kinase 2 isoform 1 [Homo sapiens] 108 1e-23
gi|71164884 vaccinia related kinase 2 isoform 1 [Homo sapiens] 108 1e-23
gi|209862855 vaccinia related kinase 2 isoform 6 [Homo sapiens] 95 1e-19
gi|71164888 vaccinia related kinase 3 isoform 2 [Homo sapiens] 82 1e-15
gi|71164886 vaccinia related kinase 3 isoform 1 [Homo sapiens] 82 1e-15
gi|4505695 3-phosphoinositide dependent protein kinase-1 isoform... 71 2e-12
gi|239756427 PREDICTED: similar to 3-phosphoinositide dependent ... 71 2e-12
gi|239745384 PREDICTED: hypothetical protein XP_002343452 [Homo ... 71 2e-12
gi|38327572 serine/threonine protein kinase 6 [Homo sapiens] 69 9e-12
gi|38327570 serine/threonine protein kinase 6 [Homo sapiens] 69 9e-12
gi|38327568 serine/threonine protein kinase 6 [Homo sapiens] 69 9e-12
>gi|73532778 casein kinase 1, gamma 3 isoform 1 [Homo sapiens]
Length = 447
Score = 924 bits (2387), Expect = 0.0
Identities = 447/447 (100%), Positives = 447/447 (100%)
Query: 1 MENKKKDKDKSDDRMARPSGRSGHNTRGTGSSSSGVLMVGPNFRVGKKIGCGNFGELRLG 60
MENKKKDKDKSDDRMARPSGRSGHNTRGTGSSSSGVLMVGPNFRVGKKIGCGNFGELRLG
Sbjct: 1 MENKKKDKDKSDDRMARPSGRSGHNTRGTGSSSSGVLMVGPNFRVGKKIGCGNFGELRLG 60
Query: 61 KNLYTNEYVAIKLEPMKSRAPQLHLEYRFYKQLGSGDGIPQVYYFGPCGKYNAMVLELLG 120
KNLYTNEYVAIKLEPMKSRAPQLHLEYRFYKQLGSGDGIPQVYYFGPCGKYNAMVLELLG
Sbjct: 61 KNLYTNEYVAIKLEPMKSRAPQLHLEYRFYKQLGSGDGIPQVYYFGPCGKYNAMVLELLG 120
Query: 121 PSLEDLFDLCDRTFSLKTVLMIAIQLISRMEYVHSKNLIYRDVKPENFLIGRPGNKTQQV 180
PSLEDLFDLCDRTFSLKTVLMIAIQLISRMEYVHSKNLIYRDVKPENFLIGRPGNKTQQV
Sbjct: 121 PSLEDLFDLCDRTFSLKTVLMIAIQLISRMEYVHSKNLIYRDVKPENFLIGRPGNKTQQV 180
Query: 181 IHIIDFGLAKEYIDPETKKHIPYREHKSLTGTARYMSINTHLGKEQSRRDDLEALGHMFM 240
IHIIDFGLAKEYIDPETKKHIPYREHKSLTGTARYMSINTHLGKEQSRRDDLEALGHMFM
Sbjct: 181 IHIIDFGLAKEYIDPETKKHIPYREHKSLTGTARYMSINTHLGKEQSRRDDLEALGHMFM 240
Query: 241 YFLRGSLPWQGLKADTLKERYQKIGDTKRATPIEVLCENFPEMATYLRYVRRLDFFEKPD 300
YFLRGSLPWQGLKADTLKERYQKIGDTKRATPIEVLCENFPEMATYLRYVRRLDFFEKPD
Sbjct: 241 YFLRGSLPWQGLKADTLKERYQKIGDTKRATPIEVLCENFPEMATYLRYVRRLDFFEKPD 300
Query: 301 YDYLRKLFTDLFDRKGYMFDYEYDWIGKQLPTPVGAVQQDPALSSNREAHQHRDKMQQSK 360
YDYLRKLFTDLFDRKGYMFDYEYDWIGKQLPTPVGAVQQDPALSSNREAHQHRDKMQQSK
Sbjct: 301 YDYLRKLFTDLFDRKGYMFDYEYDWIGKQLPTPVGAVQQDPALSSNREAHQHRDKMQQSK 360
Query: 361 NQSADHRAAWDSQQANPHHLRAHLAADRHGGSVQVVSSTNGELNTDDPTAGRSNAPITAP 420
NQSADHRAAWDSQQANPHHLRAHLAADRHGGSVQVVSSTNGELNTDDPTAGRSNAPITAP
Sbjct: 361 NQSADHRAAWDSQQANPHHLRAHLAADRHGGSVQVVSSTNGELNTDDPTAGRSNAPITAP 420
Query: 421 TEVEVMDETKCCCFFKRRKRKTIQRHK 447
TEVEVMDETKCCCFFKRRKRKTIQRHK
Sbjct: 421 TEVEVMDETKCCCFFKRRKRKTIQRHK 447
>gi|113462010 casein kinase 1, gamma 3 isoform 4 [Homo sapiens]
Length = 455
Score = 914 bits (2363), Expect = 0.0
Identities = 446/455 (98%), Positives = 446/455 (98%), Gaps = 8/455 (1%)
Query: 1 MENKKKDKDKSDDRMARPSGRSGHNTRGTGSSSSGVLMVGPNFRVGKKIGCGNFGELRLG 60
MENKKKDKDKSDDRMARPSGRSGHNTRGTGSSSSGVLMVGPNFRVGKKIGCGNFGELRLG
Sbjct: 1 MENKKKDKDKSDDRMARPSGRSGHNTRGTGSSSSGVLMVGPNFRVGKKIGCGNFGELRLG 60
Query: 61 KNLYTNEYVAIKLEPMKSRAPQLHLEYRFYKQLGSGDGIPQVYYFGPCGKYNAMVLELLG 120
KNLYTNEYVAIKLEPMKSRAPQLHLEYRFYKQLGSGDGIPQVYYFGPCGKYNAMVLELLG
Sbjct: 61 KNLYTNEYVAIKLEPMKSRAPQLHLEYRFYKQLGSGDGIPQVYYFGPCGKYNAMVLELLG 120
Query: 121 PSLEDLFDLCDRTFSLKTVLMIAIQLISRMEYVHSKNLIYRDVKPENFLIGRPGNKTQQV 180
PSLEDLFDLCDRTFSLKTVLMIAIQLISRMEYVHSKNLIYRDVKPENFLIGRPGNKTQQV
Sbjct: 121 PSLEDLFDLCDRTFSLKTVLMIAIQLISRMEYVHSKNLIYRDVKPENFLIGRPGNKTQQV 180
Query: 181 IHIIDFGLAKEYIDPETKKHIPYREHKSLTGTARYMSINTHLGKEQSRRDDLEALGHMFM 240
IHIIDFGLAKEYIDPETKKHIPYREHKSLTGTARYMSINTHLGKEQSRRDDLEALGHMFM
Sbjct: 181 IHIIDFGLAKEYIDPETKKHIPYREHKSLTGTARYMSINTHLGKEQSRRDDLEALGHMFM 240
Query: 241 YFLRGSLPWQGLKADTLKERYQKIGDTKRATPIEVLCENFPEMATYLRYVRRLDFFEKPD 300
YFLRGSLPWQGLKADTLKERYQKIGDTKRATPIEVLCENFPEMATYLRYVRRLDFFEKPD
Sbjct: 241 YFLRGSLPWQGLKADTLKERYQKIGDTKRATPIEVLCENFPEMATYLRYVRRLDFFEKPD 300
Query: 301 YDYLRKLFTDLFDRKGYMFDYEYDWIGKQLPTPVGAVQQDPALSSNREAHQHRDKMQQSK 360
YDYLRKLFTDLFDRKGYMFDYEYDWIGKQLPTPVGAVQQDPALSSNREAHQHRDKMQQSK
Sbjct: 301 YDYLRKLFTDLFDRKGYMFDYEYDWIGKQLPTPVGAVQQDPALSSNREAHQHRDKMQQSK 360
Query: 361 NQSADHRAAWDSQQANPHHLRAHLAADRHGGSVQVVSSTNGELNTDDPTAGRSNAPITAP 420
NQSADHRAAWDSQQANPHHLRAHLAADRHGGSVQVVSSTNGELNTDDPTAGRSNAPITAP
Sbjct: 361 NQSADHRAAWDSQQANPHHLRAHLAADRHGGSVQVVSSTNGELNTDDPTAGRSNAPITAP 420
Query: 421 TEVEVMDETK--------CCCFFKRRKRKTIQRHK 447
TEVEVMDET CCCFFKRRKRKTIQRHK
Sbjct: 421 TEVEVMDETNCQKVLNMWCCCFFKRRKRKTIQRHK 455
>gi|113462008 casein kinase 1, gamma 3 isoform 3 [Homo sapiens]
Length = 415
Score = 839 bits (2168), Expect = 0.0
Identities = 415/447 (92%), Positives = 415/447 (92%), Gaps = 32/447 (7%)
Query: 1 MENKKKDKDKSDDRMARPSGRSGHNTRGTGSSSSGVLMVGPNFRVGKKIGCGNFGELRLG 60
MENKKKDKDKSDDRMARPSGRSGHNTRGTGSSSSGVLMVGPNFRVGKKIGCGNFGELRLG
Sbjct: 1 MENKKKDKDKSDDRMARPSGRSGHNTRGTGSSSSGVLMVGPNFRVGKKIGCGNFGELRLG 60
Query: 61 KNLYTNEYVAIKLEPMKSRAPQLHLEYRFYKQLGSGDGIPQVYYFGPCGKYNAMVLELLG 120
KNLYTNEYVAIKLEPMKSRAPQLHLEYRFYKQLGSGDGIPQVYYFGPCGKYNAMVLELLG
Sbjct: 61 KNLYTNEYVAIKLEPMKSRAPQLHLEYRFYKQLGSGDGIPQVYYFGPCGKYNAMVLELLG 120
Query: 121 PSLEDLFDLCDRTFSLKTVLMIAIQLISRMEYVHSKNLIYRDVKPENFLIGRPGNKTQQV 180
PSLEDLFDLCDRTFSLKTVLMIAIQLISRMEYVHSKNLIYRDVKPENFLIGRPGNKTQQV
Sbjct: 121 PSLEDLFDLCDRTFSLKTVLMIAIQLISRMEYVHSKNLIYRDVKPENFLIGRPGNKTQQV 180
Query: 181 IHIIDFGLAKEYIDPETKKHIPYREHKSLTGTARYMSINTHLGKEQSRRDDLEALGHMFM 240
IHIIDFGLAKEYIDPETKKHIPYREHKSLTGTARYMSINTHLGKEQSRRDDLEALGHMFM
Sbjct: 181 IHIIDFGLAKEYIDPETKKHIPYREHKSLTGTARYMSINTHLGKEQSRRDDLEALGHMFM 240
Query: 241 YFLRGSLPWQGLKADTLKERYQKIGDTKRATPIEVLCENFPEMATYLRYVRRLDFFEKPD 300
YFLRGSLPWQGLKADTLKERYQKIGDTKRATPIEVLCENFPEMATYLRYVRRLDFFEKPD
Sbjct: 241 YFLRGSLPWQGLKADTLKERYQKIGDTKRATPIEVLCENFPEMATYLRYVRRLDFFEKPD 300
Query: 301 YDYLRKLFTDLFDRKGYMFDYEYDWIGKQLPTPVGAVQQDPALSSNREAHQHRDKMQQSK 360
YDYLRKLFTDLFDRKGYMFDYEYDWIGKQLPTPVGAVQQDPALSSNREAHQHRDKMQQSK
Sbjct: 301 YDYLRKLFTDLFDRKGYMFDYEYDWIGKQLPTPVGAVQQDPALSSNREAHQHRDKMQQSK 360
Query: 361 NQSADHRAAWDSQQANPHHLRAHLAADRHGGSVQVVSSTNGELNTDDPTAGRSNAPITAP 420
NQ VVSSTNGELNTDDPTAGRSNAPITAP
Sbjct: 361 NQ--------------------------------VVSSTNGELNTDDPTAGRSNAPITAP 388
Query: 421 TEVEVMDETKCCCFFKRRKRKTIQRHK 447
TEVEVMDETKCCCFFKRRKRKTIQRHK
Sbjct: 389 TEVEVMDETKCCCFFKRRKRKTIQRHK 415
>gi|73532780 casein kinase 1, gamma 3 isoform 2 [Homo sapiens]
Length = 423
Score = 830 bits (2144), Expect = 0.0
Identities = 414/455 (90%), Positives = 414/455 (90%), Gaps = 40/455 (8%)
Query: 1 MENKKKDKDKSDDRMARPSGRSGHNTRGTGSSSSGVLMVGPNFRVGKKIGCGNFGELRLG 60
MENKKKDKDKSDDRMARPSGRSGHNTRGTGSSSSGVLMVGPNFRVGKKIGCGNFGELRLG
Sbjct: 1 MENKKKDKDKSDDRMARPSGRSGHNTRGTGSSSSGVLMVGPNFRVGKKIGCGNFGELRLG 60
Query: 61 KNLYTNEYVAIKLEPMKSRAPQLHLEYRFYKQLGSGDGIPQVYYFGPCGKYNAMVLELLG 120
KNLYTNEYVAIKLEPMKSRAPQLHLEYRFYKQLGSGDGIPQVYYFGPCGKYNAMVLELLG
Sbjct: 61 KNLYTNEYVAIKLEPMKSRAPQLHLEYRFYKQLGSGDGIPQVYYFGPCGKYNAMVLELLG 120
Query: 121 PSLEDLFDLCDRTFSLKTVLMIAIQLISRMEYVHSKNLIYRDVKPENFLIGRPGNKTQQV 180
PSLEDLFDLCDRTFSLKTVLMIAIQLISRMEYVHSKNLIYRDVKPENFLIGRPGNKTQQV
Sbjct: 121 PSLEDLFDLCDRTFSLKTVLMIAIQLISRMEYVHSKNLIYRDVKPENFLIGRPGNKTQQV 180
Query: 181 IHIIDFGLAKEYIDPETKKHIPYREHKSLTGTARYMSINTHLGKEQSRRDDLEALGHMFM 240
IHIIDFGLAKEYIDPETKKHIPYREHKSLTGTARYMSINTHLGKEQSRRDDLEALGHMFM
Sbjct: 181 IHIIDFGLAKEYIDPETKKHIPYREHKSLTGTARYMSINTHLGKEQSRRDDLEALGHMFM 240
Query: 241 YFLRGSLPWQGLKADTLKERYQKIGDTKRATPIEVLCENFPEMATYLRYVRRLDFFEKPD 300
YFLRGSLPWQGLKADTLKERYQKIGDTKRATPIEVLCENFPEMATYLRYVRRLDFFEKPD
Sbjct: 241 YFLRGSLPWQGLKADTLKERYQKIGDTKRATPIEVLCENFPEMATYLRYVRRLDFFEKPD 300
Query: 301 YDYLRKLFTDLFDRKGYMFDYEYDWIGKQLPTPVGAVQQDPALSSNREAHQHRDKMQQSK 360
YDYLRKLFTDLFDRKGYMFDYEYDWIGKQLPTPVGAVQQDPALSSNREAHQHRDKMQQSK
Sbjct: 301 YDYLRKLFTDLFDRKGYMFDYEYDWIGKQLPTPVGAVQQDPALSSNREAHQHRDKMQQSK 360
Query: 361 NQSADHRAAWDSQQANPHHLRAHLAADRHGGSVQVVSSTNGELNTDDPTAGRSNAPITAP 420
N QVVSSTNGELNTDDPTAGRSNAPITAP
Sbjct: 361 N--------------------------------QVVSSTNGELNTDDPTAGRSNAPITAP 388
Query: 421 TEVEVMDETK--------CCCFFKRRKRKTIQRHK 447
TEVEVMDET CCCFFKRRKRKTIQRHK
Sbjct: 389 TEVEVMDETNCQKVLNMWCCCFFKRRKRKTIQRHK 423
>gi|153791733 casein kinase 1, gamma 2 [Homo sapiens]
Length = 415
Score = 686 bits (1770), Expect = 0.0
Identities = 350/450 (77%), Positives = 376/450 (83%), Gaps = 43/450 (9%)
Query: 3 NKKKDKDKSDD--RMARPSG-RSGHNTRGTGSSSSGVLMVGPNFRVGKKIGCGNFGELRL 59
+KK K ++++ RM++ G RS H R +G+SS GVLMVGPNFRVGKKIGCGNFGELRL
Sbjct: 4 DKKGGKGETEEGRRMSKAGGGRSSHGIRSSGTSS-GVLMVGPNFRVGKKIGCGNFGELRL 62
Query: 60 GKNLYTNEYVAIKLEPMKSRAPQLHLEYRFYKQLGSGDGIPQVYYFGPCGKYNAMVLELL 119
GKNLYTNEYVAIKLEP+KSRAPQLHLEYRFYKQL + +G+PQVYYFGPCGKYNAMVLELL
Sbjct: 63 GKNLYTNEYVAIKLEPIKSRAPQLHLEYRFYKQLSATEGVPQVYYFGPCGKYNAMVLELL 122
Query: 120 GPSLEDLFDLCDRTFSLKTVLMIAIQLISRMEYVHSKNLIYRDVKPENFLIGRPGNKTQQ 179
GPSLEDLFDLCDRTF+LKTVLMIAIQLI+RMEYVH+K+LIYRDVKPENFL+GRPG K Q
Sbjct: 123 GPSLEDLFDLCDRTFTLKTVLMIAIQLITRMEYVHTKSLIYRDVKPENFLVGRPGTKRQH 182
Query: 180 VIHIIDFGLAKEYIDPETKKHIPYREHKSLTGTARYMSINTHLGKEQSRRDDLEALGHMF 239
IHIIDFGLAKEYIDPETKKHIPYREHKSLTGTARYMSINTHLGKEQSRRDDLEALGHMF
Sbjct: 183 AIHIIDFGLAKEYIDPETKKHIPYREHKSLTGTARYMSINTHLGKEQSRRDDLEALGHMF 242
Query: 240 MYFLRGSLPWQGLKADTLKERYQKIGDTKRATPIEVLCENFP-EMATYLRYVRRLDFFEK 298
MYFLRGSLPWQGLKADTLKERYQKIGDTKRATPIEVLCENFP EMATYLRYVRRLDFFEK
Sbjct: 243 MYFLRGSLPWQGLKADTLKERYQKIGDTKRATPIEVLCENFPEEMATYLRYVRRLDFFEK 302
Query: 299 PDYDYLRKLFTDLFDRKGYMFDYEYDWIGKQLPTPVGAVQQDPALSSNREAHQHRDKMQ- 357
PDYDYLRKLFTDLFDR G++FDYEYDW GK LPTP+G V D L S Q RDK Q
Sbjct: 303 PDYDYLRKLFTDLFDRSGFVFDYEYDWAGKPLPTPIGTVHTD--LPSQ---PQLRDKTQP 357
Query: 358 QSKNQSADHRAAWDSQQANPHHLRAHLAADRHGGSVQVVSSTNGELNTDDPTAGRSNAPI 417
SKNQ+ ++STNGELN DDPTAG SNAPI
Sbjct: 358 HSKNQA--------------------------------LNSTNGELNADDPTAGHSNAPI 385
Query: 418 TAPTEVEVMDETKCCCFFKRRKRKTIQRHK 447
TAP EVEV DETKCCCFFKRRKRK++QRHK
Sbjct: 386 TAPAEVEVADETKCCCFFKRRKRKSLQRHK 415
>gi|98986450 casein kinase 1, gamma 1 [Homo sapiens]
Length = 422
Score = 684 bits (1765), Expect = 0.0
Identities = 345/451 (76%), Positives = 375/451 (83%), Gaps = 33/451 (7%)
Query: 1 MENKKKDKDKSDDRMARPSGRSGHNTRGTGSSSS-GVLMVGPNFRVGKKIGCGNFGELRL 59
M++ ++KD+ + RS H +R +GSSSS GVLMVGPNFRVGKKIGCGNFGELRL
Sbjct: 1 MDHPSREKDERQRTTKPMAQRSAHCSRPSGSSSSSGVLMVGPNFRVGKKIGCGNFGELRL 60
Query: 60 GKNLYTNEYVAIKLEPMKSRAPQLHLEYRFYKQLGS-GDGIPQVYYFGPCGKYNAMVLEL 118
GKNLYTNEYVAIKLEP+KSRAPQLHLEYRFYKQLGS G+G+PQVYYFGPCGKYNAMVLEL
Sbjct: 61 GKNLYTNEYVAIKLEPIKSRAPQLHLEYRFYKQLGSAGEGLPQVYYFGPCGKYNAMVLEL 120
Query: 119 LGPSLEDLFDLCDRTFSLKTVLMIAIQLISRMEYVHSKNLIYRDVKPENFLIGRPGNKTQ 178
LGPSLEDLFDLCDRTF+LKTVLMIAIQL+SRMEYVHSKNLIYRDVKPENFLIGR GNK +
Sbjct: 121 LGPSLEDLFDLCDRTFTLKTVLMIAIQLLSRMEYVHSKNLIYRDVKPENFLIGRQGNKKE 180
Query: 179 QVIHIIDFGLAKEYIDPETKKHIPYREHKSLTGTARYMSINTHLGKEQSRRDDLEALGHM 238
VIHIIDFGLAKEYIDPETKKHIPYREHKSLTGTARYMSINTHLGKEQSRRDDLEALGHM
Sbjct: 181 HVIHIIDFGLAKEYIDPETKKHIPYREHKSLTGTARYMSINTHLGKEQSRRDDLEALGHM 240
Query: 239 FMYFLRGSLPWQGLKADTLKERYQKIGDTKRATPIEVLCENFP-EMATYLRYVRRLDFFE 297
FMYFLRGSLPWQGLKADTLKERYQKIGDTKR TPIE LCENFP EMATYLRYVRRLDFFE
Sbjct: 241 FMYFLRGSLPWQGLKADTLKERYQKIGDTKRNTPIEALCENFPEEMATYLRYVRRLDFFE 300
Query: 298 KPDYDYLRKLFTDLFDRKGYMFDYEYDWIGKQLPTPVGAVQQDPALSS-NREAHQHRDKM 356
KPDY+YLR LFTDLF++KGY FDY YDW+G+ +PTPVG+V D S+ RE+H HRD+
Sbjct: 301 KPDYEYLRTLFTDLFEKKGYTFDYAYDWVGRPIPTPVGSVHVDSGASAITRESHTHRDRP 360
Query: 357 QQSKNQSADHRAAWDSQQANPHHLRAHLAADRHGGSVQVVSSTNGELNTDDPTAGRSNAP 416
Q + LR QVVSSTNGELN DDPT SNAP
Sbjct: 361 SQQQ------------------PLRN-----------QVVSSTNGELNVDDPTGAHSNAP 391
Query: 417 ITAPTEVEVMDETKCCCFFKRRKRKTIQRHK 447
ITA EVEV++E KCCCFFKR+++KT QRHK
Sbjct: 392 ITAHAEVEVVEEAKCCCFFKRKRKKTAQRHK 422
>gi|23199991 casein kinase 1 epsilon [Homo sapiens]
Length = 416
Score = 367 bits (943), Expect = e-102
Identities = 180/328 (54%), Positives = 242/328 (73%), Gaps = 7/328 (2%)
Query: 37 LMVGPNFRVGKKIGCGNFGELRLGKNLYTNEYVAIKLEPMKSRAPQLHLEYRFYKQLGSG 96
L VG +R+G+KIG G+FG++ LG N+ + E VAIKLE +K++ PQLH+E +FYK + G
Sbjct: 3 LRVGNKYRLGRKIGSGSFGDIYLGANIASGEEVAIKLECVKTKHPQLHIESKFYKMMQGG 62
Query: 97 DGIPQVYYFGPCGKYNAMVLELLGPSLEDLFDLCDRTFSLKTVLMIAIQLISRMEYVHSK 156
GIP + + G G YN MV+ELLGPSLEDLF+ C R FSLKTVL++A Q+ISR+EY+HSK
Sbjct: 63 VGIPSIKWCGAEGDYNVMVMELLGPSLEDLFNFCSRKFSLKTVLLLADQMISRIEYIHSK 122
Query: 157 NLIYRDVKPENFLIGRPGNKTQQVIHIIDFGLAKEYIDPETKKHIPYREHKSLTGTARYM 216
N I+RDVKP+NFL+G K +++IIDFGLAK+Y D T +HIPYRE+K+LTGTARY
Sbjct: 123 NFIHRDVKPDNFLMGL--GKKGNLVYIIDFGLAKKYRDARTHQHIPYRENKNLTGTARYA 180
Query: 217 SINTHLGKEQSRRDDLEALGHMFMYFLRGSLPWQGLKADTLKERYQKIGDTKRATPIEVL 276
SINTHLG EQSRRDDLE+LG++ MYF GSLPWQGLKA T +++Y++I + K +TPIEVL
Sbjct: 181 SINTHLGIEQSRRDDLESLGYVLMYFNLGSLPWQGLKAATKRQKYERISEKKMSTPIEVL 240
Query: 277 CENFP-EMATYLRYVRRLDFFEKPDYDYLRKLFTDLFDRKGYMFDYEYDWIGKQLPTPVG 335
C+ +P E +TYL + R L F +KPDY YLR+LF +LF R+G+ +DY +DW + G
Sbjct: 241 CKGYPSEFSTYLNFCRSLRFDDKPDYSYLRQLFRNLFHRQGFSYDYVFDWNMLKF----G 296
Query: 336 AVQQDPALSSNREAHQHRDKMQQSKNQS 363
A + + R H+ ++M Q + +
Sbjct: 297 AARNPEDVDRERREHEREERMGQLRGSA 324
>gi|4503093 casein kinase 1 epsilon [Homo sapiens]
Length = 416
Score = 367 bits (943), Expect = e-102
Identities = 180/328 (54%), Positives = 242/328 (73%), Gaps = 7/328 (2%)
Query: 37 LMVGPNFRVGKKIGCGNFGELRLGKNLYTNEYVAIKLEPMKSRAPQLHLEYRFYKQLGSG 96
L VG +R+G+KIG G+FG++ LG N+ + E VAIKLE +K++ PQLH+E +FYK + G
Sbjct: 3 LRVGNKYRLGRKIGSGSFGDIYLGANIASGEEVAIKLECVKTKHPQLHIESKFYKMMQGG 62
Query: 97 DGIPQVYYFGPCGKYNAMVLELLGPSLEDLFDLCDRTFSLKTVLMIAIQLISRMEYVHSK 156
GIP + + G G YN MV+ELLGPSLEDLF+ C R FSLKTVL++A Q+ISR+EY+HSK
Sbjct: 63 VGIPSIKWCGAEGDYNVMVMELLGPSLEDLFNFCSRKFSLKTVLLLADQMISRIEYIHSK 122
Query: 157 NLIYRDVKPENFLIGRPGNKTQQVIHIIDFGLAKEYIDPETKKHIPYREHKSLTGTARYM 216
N I+RDVKP+NFL+G K +++IIDFGLAK+Y D T +HIPYRE+K+LTGTARY
Sbjct: 123 NFIHRDVKPDNFLMGL--GKKGNLVYIIDFGLAKKYRDARTHQHIPYRENKNLTGTARYA 180
Query: 217 SINTHLGKEQSRRDDLEALGHMFMYFLRGSLPWQGLKADTLKERYQKIGDTKRATPIEVL 276
SINTHLG EQSRRDDLE+LG++ MYF GSLPWQGLKA T +++Y++I + K +TPIEVL
Sbjct: 181 SINTHLGIEQSRRDDLESLGYVLMYFNLGSLPWQGLKAATKRQKYERISEKKMSTPIEVL 240
Query: 277 CENFP-EMATYLRYVRRLDFFEKPDYDYLRKLFTDLFDRKGYMFDYEYDWIGKQLPTPVG 335
C+ +P E +TYL + R L F +KPDY YLR+LF +LF R+G+ +DY +DW + G
Sbjct: 241 CKGYPSEFSTYLNFCRSLRFDDKPDYSYLRQLFRNLFHRQGFSYDYVFDWNMLKF----G 296
Query: 336 AVQQDPALSSNREAHQHRDKMQQSKNQS 363
A + + R H+ ++M Q + +
Sbjct: 297 AARNPEDVDRERREHEREERMGQLRGSA 324
>gi|20544145 casein kinase 1, delta isoform 2 [Homo sapiens]
Length = 409
Score = 360 bits (925), Expect = 1e-99
Identities = 179/326 (54%), Positives = 238/326 (73%), Gaps = 9/326 (2%)
Query: 37 LMVGPNFRVGKKIGCGNFGELRLGKNLYTNEYVAIKLEPMKSRAPQLHLEYRFYKQLGSG 96
L VG +R+G+KIG G+FG++ LG ++ E VAIKLE +K++ PQLH+E + YK + G
Sbjct: 3 LRVGNRYRLGRKIGSGSFGDIYLGTDIAAGEEVAIKLECVKTKHPQLHIESKIYKMMQGG 62
Query: 97 DGIPQVYYFGPCGKYNAMVLELLGPSLEDLFDLCDRTFSLKTVLMIAIQLISRMEYVHSK 156
GIP + + G G YN MV+ELLGPSLEDLF+ C R FSLKTVL++A Q+ISR+EY+HSK
Sbjct: 63 VGIPTIRWCGAEGDYNVMVMELLGPSLEDLFNFCSRKFSLKTVLLLADQMISRIEYIHSK 122
Query: 157 NLIYRDVKPENFLIGRPGNKTQQVIHIIDFGLAKEYIDPETKKHIPYREHKSLTGTARYM 216
N I+RDVKP+NFL+G K +++IIDFGLAK+Y D T +HIPYRE+K+LTGTARY
Sbjct: 123 NFIHRDVKPDNFLMGL--GKKGNLVYIIDFGLAKKYRDARTHQHIPYRENKNLTGTARYA 180
Query: 217 SINTHLGKEQSRRDDLEALGHMFMYFLRGSLPWQGLKADTLKERYQKIGDTKRATPIEVL 276
SINTHLG EQSRRDDLE+LG++ MYF GSLPWQGLKA T +++Y++I + K +TPIEVL
Sbjct: 181 SINTHLGIEQSRRDDLESLGYVLMYFNLGSLPWQGLKAATKRQKYERISEKKMSTPIEVL 240
Query: 277 CENFP-EMATYLRYVRRLDFFEKPDYDYLRKLFTDLFDRKGYMFDYEYDWIGKQLPTPVG 335
C+ +P E ATYL + R L F +KPDY YLR+LF +LF R+G+ +DY +DW L
Sbjct: 241 CKGYPSEFATYLNFCRSLRFDDKPDYSYLRQLFRNLFHRQGFSYDYVFDW--NMLKFGAS 298
Query: 336 AVQQDPALSSNREAHQHRDKMQQSKN 361
D + RE ++++ S+N
Sbjct: 299 RAADD----AERERRDREERLRHSRN 320
>gi|20149530 casein kinase 1, delta isoform 1 [Homo sapiens]
Length = 415
Score = 360 bits (925), Expect = 1e-99
Identities = 179/326 (54%), Positives = 238/326 (73%), Gaps = 9/326 (2%)
Query: 37 LMVGPNFRVGKKIGCGNFGELRLGKNLYTNEYVAIKLEPMKSRAPQLHLEYRFYKQLGSG 96
L VG +R+G+KIG G+FG++ LG ++ E VAIKLE +K++ PQLH+E + YK + G
Sbjct: 3 LRVGNRYRLGRKIGSGSFGDIYLGTDIAAGEEVAIKLECVKTKHPQLHIESKIYKMMQGG 62
Query: 97 DGIPQVYYFGPCGKYNAMVLELLGPSLEDLFDLCDRTFSLKTVLMIAIQLISRMEYVHSK 156
GIP + + G G YN MV+ELLGPSLEDLF+ C R FSLKTVL++A Q+ISR+EY+HSK
Sbjct: 63 VGIPTIRWCGAEGDYNVMVMELLGPSLEDLFNFCSRKFSLKTVLLLADQMISRIEYIHSK 122
Query: 157 NLIYRDVKPENFLIGRPGNKTQQVIHIIDFGLAKEYIDPETKKHIPYREHKSLTGTARYM 216
N I+RDVKP+NFL+G K +++IIDFGLAK+Y D T +HIPYRE+K+LTGTARY
Sbjct: 123 NFIHRDVKPDNFLMGL--GKKGNLVYIIDFGLAKKYRDARTHQHIPYRENKNLTGTARYA 180
Query: 217 SINTHLGKEQSRRDDLEALGHMFMYFLRGSLPWQGLKADTLKERYQKIGDTKRATPIEVL 276
SINTHLG EQSRRDDLE+LG++ MYF GSLPWQGLKA T +++Y++I + K +TPIEVL
Sbjct: 181 SINTHLGIEQSRRDDLESLGYVLMYFNLGSLPWQGLKAATKRQKYERISEKKMSTPIEVL 240
Query: 277 CENFP-EMATYLRYVRRLDFFEKPDYDYLRKLFTDLFDRKGYMFDYEYDWIGKQLPTPVG 335
C+ +P E ATYL + R L F +KPDY YLR+LF +LF R+G+ +DY +DW L
Sbjct: 241 CKGYPSEFATYLNFCRSLRFDDKPDYSYLRQLFRNLFHRQGFSYDYVFDW--NMLKFGAS 298
Query: 336 AVQQDPALSSNREAHQHRDKMQQSKN 361
D + RE ++++ S+N
Sbjct: 299 RAADD----AERERRDREERLRHSRN 320
>gi|68303572 casein kinase 1, alpha 1 isoform 2 [Homo sapiens]
Length = 337
Score = 332 bits (850), Expect = 5e-91
Identities = 167/300 (55%), Positives = 217/300 (72%), Gaps = 7/300 (2%)
Query: 29 TGSSSSGVLMVGPNFRVGKKIGCGNFGELRLGKNLYTNEYVAIKLEPMKSRAPQLHLEYR 88
+ S S +VG +++ +KIG G+FG++ L N+ E VA+KLE K+R PQL E +
Sbjct: 3 SSSGSKAEFIVGGKYKLVRKIGSGSFGDIYLAINITNGEEVAVKLESQKARHPQLLYESK 62
Query: 89 FYKQLGSGDGIPQVYYFGPCGKYNAMVLELLGPSLEDLFDLCDRTFSLKTVLMIAIQLIS 148
YK L G GIP + ++G YN +V++LLGPSLEDLF+ C R F++KTVLM+A Q+IS
Sbjct: 63 LYKILQGGVGIPHIRWYGQEKDYNVLVMDLLGPSLEDLFNFCSRRFTMKTVLMLADQMIS 122
Query: 149 RMEYVHSKNLIYRDVKPENFL--IGRPGNKTQQVIHIIDFGLAKEYIDPETKKHIPYREH 206
R+EYVH+KN I+RD+KP+NFL IGR NK + +IDFGLAK+Y D T++HIPYRE
Sbjct: 123 RIEYVHTKNFIHRDIKPDNFLMGIGRHCNK----LFLIDFGLAKKYRDNRTRQHIPYRED 178
Query: 207 KSLTGTARYMSINTHLGKEQSRRDDLEALGHMFMYFLRGSLPWQGLKADTLKERYQKIGD 266
K+LTGTARY SIN HLG EQSRRDD+E+LG++ MYF R SLPWQGLKA T K++Y+KI +
Sbjct: 179 KNLTGTARYASINAHLGIEQSRRDDMESLGYVLMYFNRTSLPWQGLKAATKKQKYEKISE 238
Query: 267 TKRATPIEVLCENFP-EMATYLRYVRRLDFFEKPDYDYLRKLFTDLFDRKGYMFDYEYDW 325
K +TP+EVLC+ FP E A YL Y R L F E PDY YLR+LF LF + +DY +DW
Sbjct: 239 KKMSTPVEVLCKGFPAEFAMYLNYCRGLRFEEAPDYMYLRQLFRILFRTLNHQYDYTFDW 298
>gi|68303575 casein kinase 1, alpha 1 isoform 1 [Homo sapiens]
Length = 365
Score = 323 bits (827), Expect = 3e-88
Identities = 167/324 (51%), Positives = 218/324 (67%), Gaps = 27/324 (8%)
Query: 29 TGSSSSGVLMVGPNFRVGKKIGCGNFGELRLGKNLYTNEYVAIKLEPMKSRAPQLHLEYR 88
+ S S +VG +++ +KIG G+FG++ L N+ E VA+KLE K+R PQL E +
Sbjct: 3 SSSGSKAEFIVGGKYKLVRKIGSGSFGDIYLAINITNGEEVAVKLESQKARHPQLLYESK 62
Query: 89 FYKQLGSGDGIPQVYYFGPCGKYNAMVLELLGPSLEDLFDLCDRTFSLKTVLMIAIQLIS 148
YK L G GIP + ++G YN +V++LLGPSLEDLF+ C R F++KTVLM+A Q+IS
Sbjct: 63 LYKILQGGVGIPHIRWYGQEKDYNVLVMDLLGPSLEDLFNFCSRRFTMKTVLMLADQMIS 122
Query: 149 RMEYVHSKNLIYRDVKPENFL--IGRPGNKTQQ------------------------VIH 182
R+EYVH+KN I+RD+KP+NFL IGR NK + +
Sbjct: 123 RIEYVHTKNFIHRDIKPDNFLMGIGRHCNKCLESPVGKRKRSMTVSTSQDPSFSGLNQLF 182
Query: 183 IIDFGLAKEYIDPETKKHIPYREHKSLTGTARYMSINTHLGKEQSRRDDLEALGHMFMYF 242
+IDFGLAK+Y D T++HIPYRE K+LTGTARY SIN HLG EQSRRDD+E+LG++ MYF
Sbjct: 183 LIDFGLAKKYRDNRTRQHIPYREDKNLTGTARYASINAHLGIEQSRRDDMESLGYVLMYF 242
Query: 243 LRGSLPWQGLKADTLKERYQKIGDTKRATPIEVLCENFP-EMATYLRYVRRLDFFEKPDY 301
R SLPWQGLKA T K++Y+KI + K +TP+EVLC+ FP E A YL Y R L F E PDY
Sbjct: 243 NRTSLPWQGLKAATKKQKYEKISEKKMSTPVEVLCKGFPAEFAMYLNYCRGLRFEEAPDY 302
Query: 302 DYLRKLFTDLFDRKGYMFDYEYDW 325
YLR+LF LF + +DY +DW
Sbjct: 303 MYLRQLFRILFRTLNHQYDYTFDW 326
>gi|21624639 casein kinase 1, alpha 1-like [Homo sapiens]
Length = 337
Score = 321 bits (822), Expect = 1e-87
Identities = 172/337 (51%), Positives = 228/337 (67%), Gaps = 13/337 (3%)
Query: 31 SSSSGVLMVGPNFRVGKKIGCGNFGELRLGKNLYTNEYVAIKLEPMKSRAPQLHLEYRFY 90
S S L+VG +++ +KIG G+FG++ LG E VA+KLE K + PQL E + Y
Sbjct: 5 SGSKAELVVGGKYKLVRKIGSGSFGDVYLGITTTNGEEVAVKLESQKVKHPQLLYESKLY 64
Query: 91 KQLGSGDGIPQVYYFGPCGKYNAMVLELLGPSLEDLFDLCDRTFSLKTVLMIAIQLISRM 150
L G GIP ++++G N +V++LLGPSLEDLF+ C R F++KTVLM+A Q+ISR+
Sbjct: 65 TILQGGVGIPHMHWYGQEKDNNVLVMDLLGPSLEDLFNFCSRRFTMKTVLMLADQMISRI 124
Query: 151 EYVHSKNLIYRDVKPENFLI--GRPGNKTQQVIHIIDFGLAKEYIDPETKKHIPYREHKS 208
EYVH+KN ++RD+KP+NFL+ GR NK + +IDFGLAK+Y D T++HIPYRE K
Sbjct: 125 EYVHTKNFLHRDIKPDNFLMGTGRHCNK----LFLIDFGLAKKYRDNRTRQHIPYREDKH 180
Query: 209 LTGTARYMSINTHLGKEQSRRDDLEALGHMFMYFLRGSLPWQGLKADTLKERYQKIGDTK 268
L GT RY SIN HLG EQSRRDD+E+LG++FMYF R SLPWQGLKA T K++Y+KI + K
Sbjct: 181 LIGTVRYASINAHLGIEQSRRDDMESLGYVFMYFNRTSLPWQGLKAMTKKQKYEKISEKK 240
Query: 269 RATPIEVLCENFP-EMATYLRYVRRLDFFEKPDYDYLRKLFTDLFDRKGYMFDYEYDW-I 326
+TP+EVLC+ FP E A YL Y R L F E PDY YLR+LF LF + +DY +DW +
Sbjct: 241 MSTPVEVLCKGFPAEFAMYLNYCRGLRFEEVPDYMYLRQLFRILFRTLNHQYDYTFDWTM 300
Query: 327 GKQLPTPVGAVQQDPALSSNREAHQHRDKMQQSKNQS 363
KQ A QQ + S + Q + Q KN++
Sbjct: 301 LKQ-----KAAQQAASSSGQGQQAQTQTGKQTEKNKN 332
>gi|58761548 tau tubulin kinase 1 [Homo sapiens]
Length = 1321
Score = 154 bits (390), Expect = 1e-37
Identities = 96/290 (33%), Positives = 154/290 (53%), Gaps = 10/290 (3%)
Query: 38 MVGPNFRVGKKIGCGNFGELRLGKNLYTNEYVAIKLEPMKSRAPQLHLEYRFYKQLGSGD 97
+V ++V KKIG G FGE+ +L T E VA+K+E + L +E K+L D
Sbjct: 29 VVKDRWKVLKKIGGGGFGEIYEAMDLLTRENVALKVESAQQPKQVLKMEVAVLKKLQGKD 88
Query: 98 GIPQVYYFGPCGKYNAMVLELLGPSLEDLFDLCDR-TFSLKTVLMIAIQLISRMEYVHSK 156
+ + G K+N +V++L G +L DL R TF+L T L + Q++ +E +HS
Sbjct: 89 HVCRFIGCGRNEKFNYVVMQLQGRNLADLRRSQPRGTFTLSTTLRLGKQILESIEAIHSV 148
Query: 157 NLIYRDVKPENFLIGRPGNKTQQVIHIIDFGLAKEYIDPETKKHIPYREHKSLTGTARYM 216
++RD+KP NF +GR + T + +++DFGLA++Y + T P R GT RY
Sbjct: 149 GFLHRDIKPSNFAMGRLPS-TYRKCYMLDFGLARQYTN-TTGDVRPPRNVAGFRGTVRYA 206
Query: 217 SINTHLGKEQSRRDDLEALGHMFMYFLRGSLPWQGLKADTLKERYQKIGDTKRATPIEVL 276
S+N H +E R DDL +L +M + F G LPW+ +K +++G K +L
Sbjct: 207 SVNAHKNREMGRHDDLWSLFYMLVEFAVGQLPWRKIKDK------EQVGMIKEKYEHRML 260
Query: 277 CENFP-EMATYLRYVRRLDFFEKPDYDYLRKLFTDLFDRKGYMFDYEYDW 325
++ P E +L ++ LD+F KPDY + +F + +G + +DW
Sbjct: 261 LKHMPSEFHLFLDHIASLDYFTKPDYQLIMSVFENSMKERGIAENEAFDW 310
>gi|116812624 tau tubulin kinase 2 [Homo sapiens]
Length = 1244
Score = 148 bits (373), Expect = 1e-35
Identities = 91/291 (31%), Positives = 155/291 (53%), Gaps = 10/291 (3%)
Query: 37 LMVGPNFRVGKKIGCGNFGELRLGKNLYTNEYVAIKLEPMKSRAPQLHLEYRFYKQLGSG 96
++V ++V +KIG G FGE+ ++ T E VA+K+E + L +E K+L
Sbjct: 15 ILVKERWKVLRKIGGGGFGEIYDALDMLTRENVALKVESAQQPKQVLKMEVAVLKKLQGK 74
Query: 97 DGIPQVYYFGPCGKYNAMVLELLGPSLEDLFDLCDR-TFSLKTVLMIAIQLISRMEYVHS 155
D + + G ++N +V++L G +L DL R TF++ T L + Q++ +E +HS
Sbjct: 75 DHVCRFIGCGRNDRFNYVVMQLQGRNLADLRRSQSRGTFTISTTLRLGRQILESIESIHS 134
Query: 156 KNLIYRDVKPENFLIGRPGNKTQQVIHIIDFGLAKEYIDPETKKHIPYREHKSLTGTARY 215
++RD+KP NF +GR + T + +++DFGLA+++ + P R GT RY
Sbjct: 135 VGFLHRDIKPSNFAMGRFPS-TCRKCYMLDFGLARQFTNSCGDVRPP-RAVAGFRGTVRY 192
Query: 216 MSINTHLGKEQSRRDDLEALGHMFMYFLRGSLPWQGLKADTLKERYQKIGDTKRATPIEV 275
SIN H +E R DDL +L +M + F+ G LPW+ +K +++G K +
Sbjct: 193 ASINAHRNREMGRHDDLWSLFYMLVEFVVGQLPWRKIKDK------EQVGSIKERYDHRL 246
Query: 276 LCENF-PEMATYLRYVRRLDFFEKPDYDYLRKLFTDLFDRKGYMFDYEYDW 325
+ ++ PE + +L ++ LD+F KPDY L +F + G + +DW
Sbjct: 247 MLKHLPPEFSIFLDHISSLDYFTKPDYQLLTSVFDNSIKTFGVIESDPFDW 297
>gi|4507903 vaccinia related kinase 1 [Homo sapiens]
Length = 396
Score = 117 bits (292), Expect = 3e-26
Identities = 82/297 (27%), Positives = 141/297 (47%), Gaps = 32/297 (10%)
Query: 38 MVGPNFRVGKKIGCGNFG-----ELRLGKNLYTNEYVAIKLEPMKSRAPQLHLEYRFYKQ 92
M ++VG IG G FG ++ +++ ++ +K+EP S L E +FY++
Sbjct: 32 MAKKEWKVGLPIGQGGFGCIYLADMNSSESVGSDAPCVVKVEP--SDNGPLFTELKFYQR 89
Query: 93 LGSGD--------------GIPQVYYFGPCGK----YNAMVLELLGPSLEDLFDLCDRTF 134
+ G+P+ + G K Y M+++ G L+ +++ + F
Sbjct: 90 AAKPEQIQKWIRTRKLKYLGVPKYWGSGLHDKNGKSYRFMIMDRFGSDLQKIYEANAKRF 149
Query: 135 SLKTVLMIAIQLISRMEYVHSKNLIYRDVKPENFLIGRPGNKTQQVIHIIDFGLAKEYID 194
S KTVL ++++++ +EY+H ++ D+K N L+ K ++++D+GLA Y
Sbjct: 150 SRKTVLQLSLRILDILEYIHEHEYVHGDIKASNLLLNY---KNPDQVYLVDYGLAYRYCP 206
Query: 195 PETKKHIPYREHKSLTGTARYMSINTHLGKEQSRRDDLEALGHMFMYFLRGSLPWQGLKA 254
K + GT + SI+ H G SRR DLE LG+ + +L G LPW+
Sbjct: 207 EGVHKEYKEDPKRCHDGTIEFTSIDAHNGVAPSRRGDLEILGYCMIQWLTGHLPWEDNLK 266
Query: 255 DTLKERYQKIGDTKRATPIEVLC---ENFP-EMATYLRYVRRLDFFEKPDYDYLRKL 307
D R KI + + C +N P E+A Y+ V+ LD+ EKP Y+ LR +
Sbjct: 267 DPKYVRDSKIRYRENIASLMDKCFPEKNKPGEIAKYMETVKLLDYTEKPLYENLRDI 323
>gi|194440713 vaccinia related kinase 2 isoform 3 [Homo sapiens]
Length = 396
Score = 108 bits (269), Expect = 1e-23
Identities = 101/369 (27%), Positives = 154/369 (41%), Gaps = 44/369 (11%)
Query: 38 MVGPNFRVGKKIGCGNFGELRLGKNLYTNEYVA---IKLEPMKSRAPQLHLEYRFYKQLG 94
M G + +GKKIG G FG + L E A +K+E ++ L E +FY+++
Sbjct: 24 MEGNQWVLGKKIGSGGFGLIYLAFPTNKPEKDARHVVKVEYQENGP--LFSELKFYQRVA 81
Query: 95 SGD--------------GIPQVYYFGPCG----KYNAMVLELLGPSLEDLFDLCDRTFSL 136
D GIP Y G Y MV+E LG L+ + + TF
Sbjct: 82 KKDCIKKWIERKQLDYLGIPLFYGSGLTEFKGRSYRFMVMERLGIDLQKISGQ-NGTFKK 140
Query: 137 KTVLMIAIQLISRMEYVHSKNLIYRDVKPENFLIGRPGNKTQQVIHIIDFGLAKEYIDPE 196
TVL + I+++ +EY+H ++ D+K N L+G K +++ D+GL+ Y
Sbjct: 141 STVLQLGIRMLDVLEYIHENEYVHGDIKAANLLLGY---KNPDQVYLADYGLSYRYCPNG 197
Query: 197 TKKHIPYREHKSLTGTARYMSINTHLGKEQSRRDDLEALGHMFMYFLRGSLPW------- 249
K K GT + S++ H G SRR D+E LG+ + +L G LPW
Sbjct: 198 NHKQYQENPRKGHNGTIEFTSLDAHKGVALSRRSDVEILGYCMLRWLCGKLPWEQNLKDP 257
Query: 250 ---QGLKADTLKERYQKIGDTKRATPIEVLCENFPEMATYLRYVRRLDFFEKPDYDYLRK 306
Q K + L E Q + K A C E+A +L L + EKP+Y L+K
Sbjct: 258 VAVQTAKTNLLDELPQSV--LKWAPSGSSCC----EIAQFLVCAHSLAYDEKPNYQALKK 311
Query: 307 LFTDLFDRKGYM-FDYEYDWIGKQLPTPVGAVQQDPALSSNREAHQHRDKMQQSKNQSAD 365
+ G + F + I P Q A +AH + + +SA+
Sbjct: 312 ILNPHGIPLGPLDFSTKGQSINVHTPNSQKVDSQKAATKQVNKAHNRLIEKKVHSERSAE 371
Query: 366 HRAAWDSQQ 374
A W Q+
Sbjct: 372 SCATWKVQK 380
>gi|194440711 vaccinia related kinase 2 isoform 2 [Homo sapiens]
Length = 485
Score = 108 bits (269), Expect = 1e-23
Identities = 101/369 (27%), Positives = 154/369 (41%), Gaps = 44/369 (11%)
Query: 38 MVGPNFRVGKKIGCGNFGELRLGKNLYTNEYVA---IKLEPMKSRAPQLHLEYRFYKQLG 94
M G + +GKKIG G FG + L E A +K+E ++ L E +FY+++
Sbjct: 1 MEGNQWVLGKKIGSGGFGLIYLAFPTNKPEKDARHVVKVEYQENGP--LFSELKFYQRVA 58
Query: 95 SGD--------------GIPQVYYFGPCG----KYNAMVLELLGPSLEDLFDLCDRTFSL 136
D GIP Y G Y MV+E LG L+ + + TF
Sbjct: 59 KKDCIKKWIERKQLDYLGIPLFYGSGLTEFKGRSYRFMVMERLGIDLQKISGQ-NGTFKK 117
Query: 137 KTVLMIAIQLISRMEYVHSKNLIYRDVKPENFLIGRPGNKTQQVIHIIDFGLAKEYIDPE 196
TVL + I+++ +EY+H ++ D+K N L+G K +++ D+GL+ Y
Sbjct: 118 STVLQLGIRMLDVLEYIHENEYVHGDIKAANLLLGY---KNPDQVYLADYGLSYRYCPNG 174
Query: 197 TKKHIPYREHKSLTGTARYMSINTHLGKEQSRRDDLEALGHMFMYFLRGSLPW------- 249
K K GT + S++ H G SRR D+E LG+ + +L G LPW
Sbjct: 175 NHKQYQENPRKGHNGTIEFTSLDAHKGVALSRRSDVEILGYCMLRWLCGKLPWEQNLKDP 234
Query: 250 ---QGLKADTLKERYQKIGDTKRATPIEVLCENFPEMATYLRYVRRLDFFEKPDYDYLRK 306
Q K + L E Q + K A C E+A +L L + EKP+Y L+K
Sbjct: 235 VAVQTAKTNLLDELPQSV--LKWAPSGSSCC----EIAQFLVCAHSLAYDEKPNYQALKK 288
Query: 307 LFTDLFDRKGYM-FDYEYDWIGKQLPTPVGAVQQDPALSSNREAHQHRDKMQQSKNQSAD 365
+ G + F + I P Q A +AH + + +SA+
Sbjct: 289 ILNPHGIPLGPLDFSTKGQSINVHTPNSQKVDSQKAATKQVNKAHNRLIEKKVHSERSAE 348
Query: 366 HRAAWDSQQ 374
A W Q+
Sbjct: 349 SCATWKVQK 357
>gi|194440709 vaccinia related kinase 2 isoform 1 [Homo sapiens]
Length = 508
Score = 108 bits (269), Expect = 1e-23
Identities = 101/369 (27%), Positives = 154/369 (41%), Gaps = 44/369 (11%)
Query: 38 MVGPNFRVGKKIGCGNFGELRLGKNLYTNEYVA---IKLEPMKSRAPQLHLEYRFYKQLG 94
M G + +GKKIG G FG + L E A +K+E ++ L E +FY+++
Sbjct: 24 MEGNQWVLGKKIGSGGFGLIYLAFPTNKPEKDARHVVKVEYQENGP--LFSELKFYQRVA 81
Query: 95 SGD--------------GIPQVYYFGPCG----KYNAMVLELLGPSLEDLFDLCDRTFSL 136
D GIP Y G Y MV+E LG L+ + + TF
Sbjct: 82 KKDCIKKWIERKQLDYLGIPLFYGSGLTEFKGRSYRFMVMERLGIDLQKISGQ-NGTFKK 140
Query: 137 KTVLMIAIQLISRMEYVHSKNLIYRDVKPENFLIGRPGNKTQQVIHIIDFGLAKEYIDPE 196
TVL + I+++ +EY+H ++ D+K N L+G K +++ D+GL+ Y
Sbjct: 141 STVLQLGIRMLDVLEYIHENEYVHGDIKAANLLLGY---KNPDQVYLADYGLSYRYCPNG 197
Query: 197 TKKHIPYREHKSLTGTARYMSINTHLGKEQSRRDDLEALGHMFMYFLRGSLPW------- 249
K K GT + S++ H G SRR D+E LG+ + +L G LPW
Sbjct: 198 NHKQYQENPRKGHNGTIEFTSLDAHKGVALSRRSDVEILGYCMLRWLCGKLPWEQNLKDP 257
Query: 250 ---QGLKADTLKERYQKIGDTKRATPIEVLCENFPEMATYLRYVRRLDFFEKPDYDYLRK 306
Q K + L E Q + K A C E+A +L L + EKP+Y L+K
Sbjct: 258 VAVQTAKTNLLDELPQSV--LKWAPSGSSCC----EIAQFLVCAHSLAYDEKPNYQALKK 311
Query: 307 LFTDLFDRKGYM-FDYEYDWIGKQLPTPVGAVQQDPALSSNREAHQHRDKMQQSKNQSAD 365
+ G + F + I P Q A +AH + + +SA+
Sbjct: 312 ILNPHGIPLGPLDFSTKGQSINVHTPNSQKVDSQKAATKQVNKAHNRLIEKKVHSERSAE 371
Query: 366 HRAAWDSQQ 374
A W Q+
Sbjct: 372 SCATWKVQK 380
>gi|194440707 vaccinia related kinase 2 isoform 1 [Homo sapiens]
Length = 508
Score = 108 bits (269), Expect = 1e-23
Identities = 101/369 (27%), Positives = 154/369 (41%), Gaps = 44/369 (11%)
Query: 38 MVGPNFRVGKKIGCGNFGELRLGKNLYTNEYVA---IKLEPMKSRAPQLHLEYRFYKQLG 94
M G + +GKKIG G FG + L E A +K+E ++ L E +FY+++
Sbjct: 24 MEGNQWVLGKKIGSGGFGLIYLAFPTNKPEKDARHVVKVEYQENGP--LFSELKFYQRVA 81
Query: 95 SGD--------------GIPQVYYFGPCG----KYNAMVLELLGPSLEDLFDLCDRTFSL 136
D GIP Y G Y MV+E LG L+ + + TF
Sbjct: 82 KKDCIKKWIERKQLDYLGIPLFYGSGLTEFKGRSYRFMVMERLGIDLQKISGQ-NGTFKK 140
Query: 137 KTVLMIAIQLISRMEYVHSKNLIYRDVKPENFLIGRPGNKTQQVIHIIDFGLAKEYIDPE 196
TVL + I+++ +EY+H ++ D+K N L+G K +++ D+GL+ Y
Sbjct: 141 STVLQLGIRMLDVLEYIHENEYVHGDIKAANLLLGY---KNPDQVYLADYGLSYRYCPNG 197
Query: 197 TKKHIPYREHKSLTGTARYMSINTHLGKEQSRRDDLEALGHMFMYFLRGSLPW------- 249
K K GT + S++ H G SRR D+E LG+ + +L G LPW
Sbjct: 198 NHKQYQENPRKGHNGTIEFTSLDAHKGVALSRRSDVEILGYCMLRWLCGKLPWEQNLKDP 257
Query: 250 ---QGLKADTLKERYQKIGDTKRATPIEVLCENFPEMATYLRYVRRLDFFEKPDYDYLRK 306
Q K + L E Q + K A C E+A +L L + EKP+Y L+K
Sbjct: 258 VAVQTAKTNLLDELPQSV--LKWAPSGSSCC----EIAQFLVCAHSLAYDEKPNYQALKK 311
Query: 307 LFTDLFDRKGYM-FDYEYDWIGKQLPTPVGAVQQDPALSSNREAHQHRDKMQQSKNQSAD 365
+ G + F + I P Q A +AH + + +SA+
Sbjct: 312 ILNPHGIPLGPLDFSTKGQSINVHTPNSQKVDSQKAATKQVNKAHNRLIEKKVHSERSAE 371
Query: 366 HRAAWDSQQ 374
A W Q+
Sbjct: 372 SCATWKVQK 380
>gi|71164884 vaccinia related kinase 2 isoform 1 [Homo sapiens]
Length = 508
Score = 108 bits (269), Expect = 1e-23
Identities = 101/369 (27%), Positives = 154/369 (41%), Gaps = 44/369 (11%)
Query: 38 MVGPNFRVGKKIGCGNFGELRLGKNLYTNEYVA---IKLEPMKSRAPQLHLEYRFYKQLG 94
M G + +GKKIG G FG + L E A +K+E ++ L E +FY+++
Sbjct: 24 MEGNQWVLGKKIGSGGFGLIYLAFPTNKPEKDARHVVKVEYQENGP--LFSELKFYQRVA 81
Query: 95 SGD--------------GIPQVYYFGPCG----KYNAMVLELLGPSLEDLFDLCDRTFSL 136
D GIP Y G Y MV+E LG L+ + + TF
Sbjct: 82 KKDCIKKWIERKQLDYLGIPLFYGSGLTEFKGRSYRFMVMERLGIDLQKISGQ-NGTFKK 140
Query: 137 KTVLMIAIQLISRMEYVHSKNLIYRDVKPENFLIGRPGNKTQQVIHIIDFGLAKEYIDPE 196
TVL + I+++ +EY+H ++ D+K N L+G K +++ D+GL+ Y
Sbjct: 141 STVLQLGIRMLDVLEYIHENEYVHGDIKAANLLLGY---KNPDQVYLADYGLSYRYCPNG 197
Query: 197 TKKHIPYREHKSLTGTARYMSINTHLGKEQSRRDDLEALGHMFMYFLRGSLPW------- 249
K K GT + S++ H G SRR D+E LG+ + +L G LPW
Sbjct: 198 NHKQYQENPRKGHNGTIEFTSLDAHKGVALSRRSDVEILGYCMLRWLCGKLPWEQNLKDP 257
Query: 250 ---QGLKADTLKERYQKIGDTKRATPIEVLCENFPEMATYLRYVRRLDFFEKPDYDYLRK 306
Q K + L E Q + K A C E+A +L L + EKP+Y L+K
Sbjct: 258 VAVQTAKTNLLDELPQSV--LKWAPSGSSCC----EIAQFLVCAHSLAYDEKPNYQALKK 311
Query: 307 LFTDLFDRKGYM-FDYEYDWIGKQLPTPVGAVQQDPALSSNREAHQHRDKMQQSKNQSAD 365
+ G + F + I P Q A +AH + + +SA+
Sbjct: 312 ILNPHGIPLGPLDFSTKGQSINVHTPNSQKVDSQKAATKQVNKAHNRLIEKKVHSERSAE 371
Query: 366 HRAAWDSQQ 374
A W Q+
Sbjct: 372 SCATWKVQK 380
>gi|209862855 vaccinia related kinase 2 isoform 6 [Homo sapiens]
Length = 390
Score = 95.1 bits (235), Expect = 1e-19
Identities = 75/272 (27%), Positives = 117/272 (43%), Gaps = 21/272 (7%)
Query: 114 MVLELLGPSLEDLFDLCDRTFSLKTVLMIAIQLISRMEYVHSKNLIYRDVKPENFLIGRP 173
MV+E LG L+ + + TF TVL + I+++ +EY+H ++ D+K N L+G
Sbjct: 1 MVMERLGIDLQKISGQ-NGTFKKSTVLQLGIRMLDVLEYIHENEYVHGDIKAANLLLGY- 58
Query: 174 GNKTQQVIHIIDFGLAKEYIDPETKKHIPYREHKSLTGTARYMSINTHLGKEQSRRDDLE 233
K +++ D+GL+ Y K K GT + S++ H G SRR D+E
Sbjct: 59 --KNPDQVYLADYGLSYRYCPNGNHKQYQENPRKGHNGTIEFTSLDAHKGVALSRRSDVE 116
Query: 234 ALGHMFMYFLRGSLPW----------QGLKADTLKERYQKIGDTKRATPIEVLCENFPEM 283
LG+ + +L G LPW Q K + L E Q + K A C E+
Sbjct: 117 ILGYCMLRWLCGKLPWEQNLKDPVAVQTAKTNLLDELPQSV--LKWAPSGSSCC----EI 170
Query: 284 ATYLRYVRRLDFFEKPDYDYLRKLFTDLFDRKGYM-FDYEYDWIGKQLPTPVGAVQQDPA 342
A +L L + EKP+Y L+K+ G + F + I P Q A
Sbjct: 171 AQFLVCAHSLAYDEKPNYQALKKILNPHGIPLGPLDFSTKGQSINVHTPNSQKVDSQKAA 230
Query: 343 LSSNREAHQHRDKMQQSKNQSADHRAAWDSQQ 374
+AH + + +SA+ A W Q+
Sbjct: 231 TKQVNKAHNRLIEKKVHSERSAESCATWKVQK 262
>gi|71164888 vaccinia related kinase 3 isoform 2 [Homo sapiens]
Length = 424
Score = 81.6 bits (200), Expect = 1e-15
Identities = 59/203 (29%), Positives = 99/203 (48%), Gaps = 12/203 (5%)
Query: 110 KYNAMVLELLGPSLEDLFDLCDR-TFSLKTVLMIAIQLISRMEYVHSKNLIYRDVKPENF 168
KY +VL LG SL+ D+ + S ++VL +A +L+ +E++H ++ +V EN
Sbjct: 203 KYRFLVLPSLGRSLQSALDVSPKHVLSERSVLQVACRLLDALEFLHENEYVHGNVTAENI 262
Query: 169 LIGRPGNKTQQVIHIIDFGLAKEYIDPETKKHIPYRE--HKSLTGTARYMSINTHLGKEQ 226
+ P +++Q + + +G A Y + KH+ Y E G ++S++ H G
Sbjct: 263 FVD-PEDQSQ--VTLAGYGFAFRYCP--SGKHVAYVEGSRSPHEGDLEFISMDLHKGCGP 317
Query: 227 SRRDDLEALGHMFMYFLRGSLPWQGLKADTLKERYQKIGDTKRATPIEVLCENF----PE 282
SRR DL++LG+ + +L G LPW +T QK + P C ++
Sbjct: 318 SRRSDLQSLGYCMLKWLYGFLPWTNCLPNTEDIMKQKQKFVDKPGPFVGPCGHWIRPSET 377
Query: 283 MATYLRYVRRLDFFEKPDYDYLR 305
+ YL+ V L + EKP Y LR
Sbjct: 378 LQKYLKVVMALTYEEKPPYAMLR 400
>gi|71164886 vaccinia related kinase 3 isoform 1 [Homo sapiens]
Length = 474
Score = 81.6 bits (200), Expect = 1e-15
Identities = 59/203 (29%), Positives = 99/203 (48%), Gaps = 12/203 (5%)
Query: 110 KYNAMVLELLGPSLEDLFDLCDR-TFSLKTVLMIAIQLISRMEYVHSKNLIYRDVKPENF 168
KY +VL LG SL+ D+ + S ++VL +A +L+ +E++H ++ +V EN
Sbjct: 253 KYRFLVLPSLGRSLQSALDVSPKHVLSERSVLQVACRLLDALEFLHENEYVHGNVTAENI 312
Query: 169 LIGRPGNKTQQVIHIIDFGLAKEYIDPETKKHIPYRE--HKSLTGTARYMSINTHLGKEQ 226
+ P +++Q + + +G A Y + KH+ Y E G ++S++ H G
Sbjct: 313 FVD-PEDQSQ--VTLAGYGFAFRYCP--SGKHVAYVEGSRSPHEGDLEFISMDLHKGCGP 367
Query: 227 SRRDDLEALGHMFMYFLRGSLPWQGLKADTLKERYQKIGDTKRATPIEVLCENF----PE 282
SRR DL++LG+ + +L G LPW +T QK + P C ++
Sbjct: 368 SRRSDLQSLGYCMLKWLYGFLPWTNCLPNTEDIMKQKQKFVDKPGPFVGPCGHWIRPSET 427
Query: 283 MATYLRYVRRLDFFEKPDYDYLR 305
+ YL+ V L + EKP Y LR
Sbjct: 428 LQKYLKVVMALTYEEKPPYAMLR 450
>gi|4505695 3-phosphoinositide dependent protein kinase-1 isoform 1
[Homo sapiens]
Length = 556
Score = 70.9 bits (172), Expect = 2e-12
Identities = 60/222 (27%), Positives = 100/222 (45%), Gaps = 32/222 (14%)
Query: 42 NFRVGKKIGCGNFGELRLGKNLYTNEYVAIKLEPMK-------------SRAPQLHLEYR 88
+F+ GK +G G+F + L + L T+ AIK+ + R L++
Sbjct: 81 DFKFGKILGEGSFSTVVLARELATSREYAIKILEKRHIIKENKVPYVTRERDVMSRLDHP 140
Query: 89 FYKQLGSGDGIPQVYYFGPCGKYNAMVLELLGPSLEDLFDLCDRTFSLKTVLMIAIQLIS 148
F+ +L + YFG N +L+ + + + C R ++ +++S
Sbjct: 141 FFVKLYFTFQDDEKLYFGLSYAKNGELLKYIR-KIGSFDETCTRFYTA--------EIVS 191
Query: 149 RMEYVHSKNLIYRDVKPENFLIGRPGNKTQQVIHIIDFGLAKEYIDPETKKHIPYREHKS 208
+EY+H K +I+RD+KPEN L+ I I DFG AK + PE+K+ S
Sbjct: 192 ALEYLHGKGIIHRDLKPENILLNE-----DMHIQITDFGTAK-VLSPESKQ----ARANS 241
Query: 209 LTGTARYMSINTHLGKEQSRRDDLEALGHMFMYFLRGSLPWQ 250
GTA+Y+S K + DL ALG + + G P++
Sbjct: 242 FVGTAQYVSPELLTEKSACKSSDLWALGCIIYQLVAGLPPFR 283
>gi|239756427 PREDICTED: similar to 3-phosphoinositide dependent
protein kinase-1 [Homo sapiens]
Length = 471
Score = 70.9 bits (172), Expect = 2e-12
Identities = 60/222 (27%), Positives = 100/222 (45%), Gaps = 32/222 (14%)
Query: 42 NFRVGKKIGCGNFGELRLGKNLYTNEYVAIKLEPMK-------------SRAPQLHLEYR 88
+F+ GK +G G+F + L + L T+ AIK+ + R L++
Sbjct: 100 DFKFGKILGEGSFSTVVLARELATSREYAIKILEKRHIIKENKVPYVTRERDVMSRLDHP 159
Query: 89 FYKQLGSGDGIPQVYYFGPCGKYNAMVLELLGPSLEDLFDLCDRTFSLKTVLMIAIQLIS 148
F+ +L + YFG N +L+ + + + C R ++ +++S
Sbjct: 160 FFVKLYFTFQTTRRLYFGLSYAKNGELLKYIR-KIGSFDETCTRFYTA--------EIVS 210
Query: 149 RMEYVHSKNLIYRDVKPENFLIGRPGNKTQQVIHIIDFGLAKEYIDPETKKHIPYREHKS 208
+EY+H K +I+RD+KPEN L+ I I DFG AK + PE+K+ S
Sbjct: 211 ALEYLHGKGIIHRDLKPENILLNE-----DMHIQITDFGTAK-VLSPESKQ----ARANS 260
Query: 209 LTGTARYMSINTHLGKEQSRRDDLEALGHMFMYFLRGSLPWQ 250
GTA+Y+S K + DL ALG + + G P++
Sbjct: 261 FVGTAQYVSPELLTEKSACKSSDLWALGCIIYQLVAGLPPFR 302
>gi|239745384 PREDICTED: hypothetical protein XP_002343452 [Homo
sapiens]
Length = 396
Score = 70.9 bits (172), Expect = 2e-12
Identities = 60/222 (27%), Positives = 100/222 (45%), Gaps = 32/222 (14%)
Query: 42 NFRVGKKIGCGNFGELRLGKNLYTNEYVAIKLEPMK-------------SRAPQLHLEYR 88
+F+ GK +G G+F + L + L T+ AIK+ + R L++
Sbjct: 54 DFKFGKILGEGSFSTVVLARELATSREYAIKILEKRHIIKENKVPYVTRERDVMSRLDHP 113
Query: 89 FYKQLGSGDGIPQVYYFGPCGKYNAMVLELLGPSLEDLFDLCDRTFSLKTVLMIAIQLIS 148
F+ +L + YFG N +L+ + + + C R ++ +++S
Sbjct: 114 FFVKLYFTFQDDEKLYFGLSYAKNGELLKYIR-KIGSFDETCTRFYTA--------EIVS 164
Query: 149 RMEYVHSKNLIYRDVKPENFLIGRPGNKTQQVIHIIDFGLAKEYIDPETKKHIPYREHKS 208
+EY+H K +I+RD+KPEN L+ I I DFG AK + PE+K+ S
Sbjct: 165 ALEYLHGKGIIHRDLKPENILLNE-----DMHIQITDFGTAK-VLSPESKQ----ARANS 214
Query: 209 LTGTARYMSINTHLGKEQSRRDDLEALGHMFMYFLRGSLPWQ 250
GTA+Y+S K + DL ALG + + G P++
Sbjct: 215 FVGTAQYVSPELLTEKSACKSSDLWALGCIIYQLVAGLPPFR 256
>gi|38327572 serine/threonine protein kinase 6 [Homo sapiens]
Length = 403
Score = 68.9 bits (167), Expect = 9e-12
Identities = 59/238 (24%), Positives = 106/238 (44%), Gaps = 27/238 (11%)
Query: 42 NFRVGKKIGCGNFGELRLGKNLYTNEYVAIKLEPMKSRAPQLHLEYRFYKQLGSGDGI-- 99
+F +G+ +G G FG + L + + +A+K+ K++ + +E++ +++ +
Sbjct: 132 DFEIGRPLGKGKFGNVYLAREKQSKFILALKVL-FKAQLEKAGVEHQLRREVEIQSHLRH 190
Query: 100 PQV-----YYFGPCGKYNAMVLELLGPSLEDLFDLCDRTFSLKTVLMIAIQLISRMEYVH 154
P + Y+ Y + LG +L L F + +L + + Y H
Sbjct: 191 PNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSK--FDEQRTATYITELANALSYCH 248
Query: 155 SKNLIYRDVKPENFLIGRPGNKTQQVIHIIDFGLAKEYIDPETKKHIPYREHKSLTGTAR 214
SK +I+RD+KPEN L+G G + I DFG + H P +L GT
Sbjct: 249 SKRVIHRDIKPENLLLGSAGE-----LKIADFGWS---------VHAPSSRRTTLCGTLD 294
Query: 215 YMSINTHLGKEQSRRDDLEALGHMFMYFLRGSLPWQGLKADTLKERYQKIGDTKRATP 272
Y+ G+ + DL +LG + FL G P++ A+T +E Y++I + P
Sbjct: 295 YLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFE---ANTYQETYKRISRVEFTFP 349
>gi|38327570 serine/threonine protein kinase 6 [Homo sapiens]
Length = 403
Score = 68.9 bits (167), Expect = 9e-12
Identities = 59/238 (24%), Positives = 106/238 (44%), Gaps = 27/238 (11%)
Query: 42 NFRVGKKIGCGNFGELRLGKNLYTNEYVAIKLEPMKSRAPQLHLEYRFYKQLGSGDGI-- 99
+F +G+ +G G FG + L + + +A+K+ K++ + +E++ +++ +
Sbjct: 132 DFEIGRPLGKGKFGNVYLAREKQSKFILALKVL-FKAQLEKAGVEHQLRREVEIQSHLRH 190
Query: 100 PQV-----YYFGPCGKYNAMVLELLGPSLEDLFDLCDRTFSLKTVLMIAIQLISRMEYVH 154
P + Y+ Y + LG +L L F + +L + + Y H
Sbjct: 191 PNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSK--FDEQRTATYITELANALSYCH 248
Query: 155 SKNLIYRDVKPENFLIGRPGNKTQQVIHIIDFGLAKEYIDPETKKHIPYREHKSLTGTAR 214
SK +I+RD+KPEN L+G G + I DFG + H P +L GT
Sbjct: 249 SKRVIHRDIKPENLLLGSAGE-----LKIADFGWS---------VHAPSSRRTTLCGTLD 294
Query: 215 YMSINTHLGKEQSRRDDLEALGHMFMYFLRGSLPWQGLKADTLKERYQKIGDTKRATP 272
Y+ G+ + DL +LG + FL G P++ A+T +E Y++I + P
Sbjct: 295 YLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFE---ANTYQETYKRISRVEFTFP 349
>gi|38327568 serine/threonine protein kinase 6 [Homo sapiens]
Length = 403
Score = 68.9 bits (167), Expect = 9e-12
Identities = 59/238 (24%), Positives = 106/238 (44%), Gaps = 27/238 (11%)
Query: 42 NFRVGKKIGCGNFGELRLGKNLYTNEYVAIKLEPMKSRAPQLHLEYRFYKQLGSGDGI-- 99
+F +G+ +G G FG + L + + +A+K+ K++ + +E++ +++ +
Sbjct: 132 DFEIGRPLGKGKFGNVYLAREKQSKFILALKVL-FKAQLEKAGVEHQLRREVEIQSHLRH 190
Query: 100 PQV-----YYFGPCGKYNAMVLELLGPSLEDLFDLCDRTFSLKTVLMIAIQLISRMEYVH 154
P + Y+ Y + LG +L L F + +L + + Y H
Sbjct: 191 PNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSK--FDEQRTATYITELANALSYCH 248
Query: 155 SKNLIYRDVKPENFLIGRPGNKTQQVIHIIDFGLAKEYIDPETKKHIPYREHKSLTGTAR 214
SK +I+RD+KPEN L+G G + I DFG + H P +L GT
Sbjct: 249 SKRVIHRDIKPENLLLGSAGE-----LKIADFGWS---------VHAPSSRRTTLCGTLD 294
Query: 215 YMSINTHLGKEQSRRDDLEALGHMFMYFLRGSLPWQGLKADTLKERYQKIGDTKRATP 272
Y+ G+ + DL +LG + FL G P++ A+T +E Y++I + P
Sbjct: 295 YLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFE---ANTYQETYKRISRVEFTFP 349
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.319 0.136 0.411
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 17,689,313
Number of Sequences: 37866
Number of extensions: 808835
Number of successful extensions: 3151
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 457
Number of HSP's successfully gapped in prelim test: 254
Number of HSP's that attempted gapping in prelim test: 2213
Number of HSP's gapped (non-prelim): 851
length of query: 447
length of database: 18,247,518
effective HSP length: 105
effective length of query: 342
effective length of database: 14,271,588
effective search space: 4880883096
effective search space used: 4880883096
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.