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Search of human proteins with 7305503
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|7305503 stomatin (EPB72)-like 2 [Homo sapiens]
(356 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|7305503 stomatin (EPB72)-like 2 [Homo sapiens] 677 0.0
gi|221316744 stomatin-like 3 isoform 2 [Homo sapiens] 120 2e-27
gi|21686995 stomatin-like 3 isoform 1 [Homo sapiens] 120 2e-27
gi|38016911 stomatin isoform a [Homo sapiens] 110 2e-24
gi|7657615 podocin [Homo sapiens] 78 1e-14
gi|20149563 stomatin (EPB72)-like 1 [Homo sapiens] 61 2e-09
gi|5031699 flotillin 1 [Homo sapiens] 55 1e-07
gi|94538362 flotillin 2 [Homo sapiens] 49 5e-06
gi|153791497 ciliary rootlet coiled-coil [Homo sapiens] 39 0.005
gi|237858619 polyamine modulated factor 1 binding protein 1 isof... 35 0.13
gi|153791662 coiled-coil domain containing 71 [Homo sapiens] 34 0.18
gi|48762942 huntingtin interacting protein-1-related [Homo sapiens] 34 0.23
gi|21735548 centrosomal protein 2 [Homo sapiens] 34 0.23
gi|239750456 PREDICTED: similar to KIAA0655 protein [Homo sapiens] 34 0.23
gi|153945790 myosin, heavy chain 8, skeletal muscle, perinatal [... 34 0.23
gi|41322923 plectin 1 isoform 11 [Homo sapiens] 33 0.30
gi|41322914 plectin 1 isoform 10 [Homo sapiens] 33 0.30
gi|41322919 plectin 1 isoform 8 [Homo sapiens] 33 0.30
gi|41322910 plectin 1 isoform 7 [Homo sapiens] 33 0.30
gi|41322916 plectin 1 isoform 6 [Homo sapiens] 33 0.30
gi|41322908 plectin 1 isoform 3 [Homo sapiens] 33 0.30
gi|41322912 plectin 1 isoform 2 [Homo sapiens] 33 0.30
gi|47607492 plectin 1 isoform 1 [Homo sapiens] 33 0.30
gi|91208418 transcription elongation regulator 1 isoform 2 [Homo... 33 0.30
gi|21327715 transcription elongation regulator 1 isoform 1 [Homo... 33 0.30
gi|56961680 coiled-coil domain containing 147 [Homo sapiens] 32 1.1
gi|4507877 vinculin isoform VCL [Homo sapiens] 31 1.5
gi|7669550 vinculin isoform meta-VCL [Homo sapiens] 31 1.5
gi|122937195 plasma membrane associated protein, S3-12 [Homo sap... 31 1.9
gi|7657455 pescadillo homolog 1, containing BRCT domain [Homo sa... 30 2.5
>gi|7305503 stomatin (EPB72)-like 2 [Homo sapiens]
Length = 356
Score = 677 bits (1747), Expect = 0.0
Identities = 356/356 (100%), Positives = 356/356 (100%)
Query: 1 MLARAARGTGALLLRGSLLASGRAPRRASSGLPRNTVVLFVPQQEAWVVERMGRFHRILE 60
MLARAARGTGALLLRGSLLASGRAPRRASSGLPRNTVVLFVPQQEAWVVERMGRFHRILE
Sbjct: 1 MLARAARGTGALLLRGSLLASGRAPRRASSGLPRNTVVLFVPQQEAWVVERMGRFHRILE 60
Query: 61 PGLNILIPVLDRIRYVQSLKEIVINVPEQSAVTLDNVTLQIDGVLYLRIMDPYKASYGVE 120
PGLNILIPVLDRIRYVQSLKEIVINVPEQSAVTLDNVTLQIDGVLYLRIMDPYKASYGVE
Sbjct: 61 PGLNILIPVLDRIRYVQSLKEIVINVPEQSAVTLDNVTLQIDGVLYLRIMDPYKASYGVE 120
Query: 121 DPEYAVTQLAQTTMRSELGKLSLDKVFRERESLNASIVDAINQAADCWGIRCLRYEIKDI 180
DPEYAVTQLAQTTMRSELGKLSLDKVFRERESLNASIVDAINQAADCWGIRCLRYEIKDI
Sbjct: 121 DPEYAVTQLAQTTMRSELGKLSLDKVFRERESLNASIVDAINQAADCWGIRCLRYEIKDI 180
Query: 181 HVPPRVKESMQMQVEAERRKRATVLESEGTRESAINVAEGKKQAQILASEAEKAEQINQA 240
HVPPRVKESMQMQVEAERRKRATVLESEGTRESAINVAEGKKQAQILASEAEKAEQINQA
Sbjct: 181 HVPPRVKESMQMQVEAERRKRATVLESEGTRESAINVAEGKKQAQILASEAEKAEQINQA 240
Query: 241 AGEASAVLAKAKAKAEAIRILAAALTQHNGDAAASLTVAEQYVSAFSKLAKDSNTILLPS 300
AGEASAVLAKAKAKAEAIRILAAALTQHNGDAAASLTVAEQYVSAFSKLAKDSNTILLPS
Sbjct: 241 AGEASAVLAKAKAKAEAIRILAAALTQHNGDAAASLTVAEQYVSAFSKLAKDSNTILLPS 300
Query: 301 NPGDVTSMVAQAMGVYGALTKAPVPGTPDSLSSGSSRDVQGTDASLDEELDRVKMS 356
NPGDVTSMVAQAMGVYGALTKAPVPGTPDSLSSGSSRDVQGTDASLDEELDRVKMS
Sbjct: 301 NPGDVTSMVAQAMGVYGALTKAPVPGTPDSLSSGSSRDVQGTDASLDEELDRVKMS 356
>gi|221316744 stomatin-like 3 isoform 2 [Homo sapiens]
Length = 282
Score = 120 bits (301), Expect = 2e-27
Identities = 72/199 (36%), Positives = 111/199 (55%), Gaps = 7/199 (3%)
Query: 41 VPQQEAWVVERMGRFH--RILEPGLNILIPVLDRIRYVQSLKEIVINVPEQSAVTLDNVT 98
+ + E VV R+GR + PGL +++P +D V L+ + N+P Q +T D+VT
Sbjct: 45 IKEYERAVVFRLGRIQADKAKGPGLILVLPCIDVFVKVD-LRTVTCNIPPQEILTRDSVT 103
Query: 99 LQIDGVLYLRIMDPYKASYGVEDPEYAVTQLAQTTMRSELGKLSLDKVFRERESLNASIV 158
Q+DGV+Y RI A V D A LAQTT+R+ LG +L ++ RE + SI
Sbjct: 104 TQVDGVVYYRIYSAVSAVANVNDVHQATFLLAQTTLRNVLGTQTLSQILAGREEIAHSIQ 163
Query: 159 DAINQAADCWGIRCLRYEIKDIHVPPRVKESMQMQVEAERRKRATVLESEGTRESAINVA 218
++ A + WGIR R EIKD+ +P +++ SM + EA R RA VL +EG +N +
Sbjct: 164 TLLDDATELWGIRVARVEIKDVRIPVQLQRSMAAEAEATREARAKVLAAEG----EMNAS 219
Query: 219 EGKKQAQILASEAEKAEQI 237
+ K A ++ +E+ A Q+
Sbjct: 220 KSLKSASMVLAESPIALQL 238
>gi|21686995 stomatin-like 3 isoform 1 [Homo sapiens]
Length = 291
Score = 120 bits (301), Expect = 2e-27
Identities = 72/199 (36%), Positives = 111/199 (55%), Gaps = 7/199 (3%)
Query: 41 VPQQEAWVVERMGRFH--RILEPGLNILIPVLDRIRYVQSLKEIVINVPEQSAVTLDNVT 98
+ + E VV R+GR + PGL +++P +D V L+ + N+P Q +T D+VT
Sbjct: 54 IKEYERAVVFRLGRIQADKAKGPGLILVLPCIDVFVKVD-LRTVTCNIPPQEILTRDSVT 112
Query: 99 LQIDGVLYLRIMDPYKASYGVEDPEYAVTQLAQTTMRSELGKLSLDKVFRERESLNASIV 158
Q+DGV+Y RI A V D A LAQTT+R+ LG +L ++ RE + SI
Sbjct: 113 TQVDGVVYYRIYSAVSAVANVNDVHQATFLLAQTTLRNVLGTQTLSQILAGREEIAHSIQ 172
Query: 159 DAINQAADCWGIRCLRYEIKDIHVPPRVKESMQMQVEAERRKRATVLESEGTRESAINVA 218
++ A + WGIR R EIKD+ +P +++ SM + EA R RA VL +EG +N +
Sbjct: 173 TLLDDATELWGIRVARVEIKDVRIPVQLQRSMAAEAEATREARAKVLAAEG----EMNAS 228
Query: 219 EGKKQAQILASEAEKAEQI 237
+ K A ++ +E+ A Q+
Sbjct: 229 KSLKSASMVLAESPIALQL 247
>gi|38016911 stomatin isoform a [Homo sapiens]
Length = 288
Score = 110 bits (275), Expect = 2e-24
Identities = 61/202 (30%), Positives = 113/202 (55%), Gaps = 7/202 (3%)
Query: 38 VLFVPQQEAWVVERMGRFHR--ILEPGLNILIPVLDRIRYVQSLKEIVINVPEQSAVTLD 95
+ + + E ++ R+GR + PGL ++P D V ++ I ++P Q +T D
Sbjct: 54 IKIIKEYERAIIFRLGRILQGGAKGPGLFFILPCTDSFIKVD-MRTISFDIPPQEILTKD 112
Query: 96 NVTLQIDGVLYLRIMDPYKASYGVEDPEYAVTQLAQTTMRSELGKLSLDKVFRERESLNA 155
+VT+ +DGV+Y R+ + A + + + A LAQTT+R+ LG +L ++ +RE +
Sbjct: 113 SVTISVDGVVYYRVQNATLAVANITNADSATRLLAQTTLRNVLGTKNLSQILSDREEIAH 172
Query: 156 SIVDAINQAADCWGIRCLRYEIKDIHVPPRVKESMQMQVEAERRKRATVLESEGTRESAI 215
++ ++ A D WGI+ R EIKD+ +P +++ +M + EA R RA V+ +EG +
Sbjct: 173 NMQSTLDDATDAWGIKVERVEIKDVKLPVQLQRAMAAEAEASREARAKVIAAEG----EM 228
Query: 216 NVAEGKKQAQILASEAEKAEQI 237
N + K+A ++ +E+ A Q+
Sbjct: 229 NASRALKEASMVITESPAALQL 250
>gi|7657615 podocin [Homo sapiens]
Length = 383
Score = 78.2 bits (191), Expect = 1e-14
Identities = 50/179 (27%), Positives = 88/179 (49%), Gaps = 3/179 (1%)
Query: 38 VLFVPQQEAWVVERMGRF--HRILEPGLNILIPVLDRIRYVQSLKEIVINVPEQSAVTLD 95
V V + E ++ R+G R PGL +P LD V L+ + +P VT D
Sbjct: 125 VKVVQEYERVIIFRLGHLLPGRAKGPGLFFFLPCLDTYHKVD-LRLQTLEIPFHEIVTKD 183
Query: 96 NVTLQIDGVLYLRIMDPYKASYGVEDPEYAVTQLAQTTMRSELGKLSLDKVFRERESLNA 155
++ID + Y R+ + + AV L QTTM+ L SL ++ ER+S+
Sbjct: 184 MFIMEIDAICYYRMENASLLLSSLAHVSKAVQFLVQTTMKRLLAHRSLTEILLERKSIAQ 243
Query: 156 SIVDAINQAADCWGIRCLRYEIKDIHVPPRVKESMQMQVEAERRKRATVLESEGTRESA 214
A++ WGI+ R EIKD+ +P ++ S+ ++ EA+R+ + ++ +E + ++
Sbjct: 244 DAKVALDSVTCIWGIKVERIEIKDVRLPAGLQHSLAVEAEAQRQAKVRMIAAEAEKAAS 302
>gi|20149563 stomatin (EPB72)-like 1 [Homo sapiens]
Length = 398
Score = 60.8 bits (146), Expect = 2e-09
Identities = 39/137 (28%), Positives = 61/137 (44%), Gaps = 1/137 (0%)
Query: 41 VPQQEAWVVERMGRFHRILEPGLNILIPVLDRIRYVQSLKEIVINVPEQSAVTLDNVTLQ 100
VP E +V R+GR PG+ +L+P +D + V L+ NVP + D L
Sbjct: 82 VPTYERMIVFRLGRIRTPQGPGMVLLLPFIDSFQRVD-LRTRAFNVPPCKLASKDGAVLS 140
Query: 101 IDGVLYLRIMDPYKASYGVEDPEYAVTQLAQTTMRSELGKLSLDKVFRERESLNASIVDA 160
+ + RI DP + V+D A AQ M L K L ++ E+ ++ ++
Sbjct: 141 VGADVQFRIWDPVLSVMTVKDLNTATRMTAQNAMTKALLKRPLREIQMEKLKISDQLLLE 200
Query: 161 INQAADCWGIRCLRYEI 177
IN WG+ R E+
Sbjct: 201 INDVTRAWGLEVDRVEL 217
>gi|5031699 flotillin 1 [Homo sapiens]
Length = 427
Score = 54.7 bits (130), Expect = 1e-07
Identities = 50/255 (19%), Positives = 113/255 (44%), Gaps = 20/255 (7%)
Query: 45 EAWVVERMGRFHRILEPGLNILI-PVLDRIRYVQSLKEIVINVPEQSAVTLDNVTLQIDG 103
EA VV R ++ G + + P + +I+ + SL + +NV + T V + + G
Sbjct: 9 EAMVVSGFCRSPPVMVAGGRVFVLPCIQQIQRI-SLNTLTLNVKSEKVYTRHGVPISVTG 67
Query: 104 VLYLRIMDPYKASYGVE------DPEYAVTQLAQTTM----RSELGKLSLDKVFRERESL 153
+ ++I K E + +A T+ R+ + +++++++++R+
Sbjct: 68 IAQVKIQGQNKEMLAAACQMFLGKTEAEIAHIALETLEGHQRAIMAHMTVEEIYKDRQKF 127
Query: 154 NASIVDAINQAADCWGIRCLRYEIKDIHVPPRVKESMQMQVEAERRKRATVLESEGTRES 213
+ + + GI + Y +KDIH S+ A+ +K A + E+E R++
Sbjct: 128 SEQVFKVASSDLVNMGISVVSYTLKDIHDDQDYLHSLGKARTAQVQKDARIGEAEAKRDA 187
Query: 214 AINVAEGKKQ-------AQILASEAEKAEQINQAAGEASAVLAKAKAKAEAIRILAAALT 266
I A+ K++ ++I ++A++ ++ +AA + +A+A A ++ A
Sbjct: 188 GIREAKAKQEKVSAQYLSEIEMAKAQRDYELKKAAYDIEVNTRRAQADL-AYQLQVAKTK 246
Query: 267 QHNGDAAASLTVAEQ 281
Q + + V E+
Sbjct: 247 QQIEEQRVQVQVVER 261
Score = 37.0 bits (84), Expect = 0.027
Identities = 52/205 (25%), Positives = 85/205 (41%), Gaps = 34/205 (16%)
Query: 114 KASYGVEDPEYAVTQLAQTTMRSELGKLSLDKVFRERESLNASIVDAINQAADCWGIRCL 173
KA+Y +E T+ AQ + +L +++ K E + + +V+ Q A
Sbjct: 220 KAAYDIE----VNTRRAQADLAYQL-QVAKTKQQIEEQRVQVQVVERAQQVA-------- 266
Query: 174 RYEIKDIHVPPRVKESMQMQVEAERRKRATVLESEGTRESAINVAEGKKQAQILASEAEK 233
+++ + R KE +EA RK A E R +AE +K I+ +EAE
Sbjct: 267 ---VQEQEIARREKE-----LEARVRKPA-----EAERYKLERLAEAEKSQLIMQAEAEA 313
Query: 234 AEQINQAAGEASAVLAKAKAKAEAIRILAAALTQHNGDAAASLTVAEQYVSAFSKLAKDS 293
A + GEA A A+A+AEA ++ A +A A Q KL + +
Sbjct: 314 ASV--RMRGEAEAFAIGARARAEAEQMAKKA------EAFQLYQEAAQLDMLLEKLPQVA 365
Query: 294 NTILLPSNPGDVTSMVAQAMGVYGA 318
I P + ++V+ G GA
Sbjct: 366 EEISGPLTSANKITLVSSGSGTMGA 390
>gi|94538362 flotillin 2 [Homo sapiens]
Length = 428
Score = 49.3 bits (116), Expect = 5e-06
Identities = 55/191 (28%), Positives = 88/191 (46%), Gaps = 9/191 (4%)
Query: 125 AVTQLAQTTMRSELGKLSLDKVFRERESLNASIVDAINQAADCWGIRCLRYEIKDIHVPP 184
A T++A + EL K + + + + A + + A + IR EI+ +
Sbjct: 208 ADTKIADSKRAFELQKSAFSEEVNIKTA-EAQLAYELQGAREQQKIRQEEIEIEVVQRKK 266
Query: 185 RVKESMQMQVEAERRKRATVLE-SEGTRESAINVAEGKKQAQILASEAEKAEQINQAAGE 243
++ Q + ++ ATV +E +AEG+K Q+L ++AE AE+I + GE
Sbjct: 267 QIAVEAQEILRTDKELIATVRRPAEAEAHRIQQIAEGEKVKQVLLAQAE-AEKIRK-IGE 324
Query: 244 ASAVLAKAKAKAEAIRI-LAAALTQHNGDAAASLTVAEQYVSAFSKLA----KDSNTILL 298
A A + +A KAEA R+ L A Q GDAA V E +K+A K ++L
Sbjct: 325 AEAAVIEAMGKAEAERMKLKAEAYQKYGDAAKMALVLEALPQIAAKIAAPLTKVDEIVVL 384
Query: 299 PSNPGDVTSMV 309
+ VTS V
Sbjct: 385 SGDNSKVTSEV 395
Score = 46.2 bits (108), Expect = 4e-05
Identities = 40/193 (20%), Positives = 87/193 (45%), Gaps = 16/193 (8%)
Query: 78 SLKEIVINVPEQSAVTLDNVTLQIDGVLYLRIMDPYKA---------SYGVEDPEYAVTQ 128
SL+ + + + T + V L + GV ++IM + V+D + V Q
Sbjct: 46 SLEIMTLQPRCEDVETAEGVALTVTGVAQVKIMTEKELLAVACEQFLGKNVQDIKNVVLQ 105
Query: 129 LAQTTMRSELGKLSLDKVFRERESLNASIVDAINQAADCWGIRCLRYEIKDIHVPPRVKE 188
+ +RS LG L++++++++R+ + + GI L + IKD++
Sbjct: 106 TLEGHLRSILGTLTVEQIYQDRDQFAKLVREVAAPDVGRMGIEILSFTIKDVYDKVDYLS 165
Query: 189 SMQMQVEAERRKRATVLESEGTRESAINVAEGKKQ-------AQILASEAEKAEQINQAA 241
S+ A ++ A + +E R++ I AE KK+ A +++++A ++ ++A
Sbjct: 166 SLGKTQTAVVQRDADIGVAEAERDAGIREAECKKEMLDVKFMADTKIADSKRAFELQKSA 225
Query: 242 GEASAVLAKAKAK 254
+ A+A+
Sbjct: 226 FSEEVNIKTAEAQ 238
>gi|153791497 ciliary rootlet coiled-coil [Homo sapiens]
Length = 2017
Score = 39.3 bits (90), Expect = 0.005
Identities = 33/112 (29%), Positives = 52/112 (46%), Gaps = 4/112 (3%)
Query: 187 KESM-QMQVEAERRKRATVLESEGTRESAINVAEGKKQAQILASEAEKAEQINQAAGEAS 245
KE M Q V+AER +A++ E E + + +K+A EAE+A+ +Q E
Sbjct: 966 KELMAQKLVQAEREAQASLREQRAAHEEDLQRLQREKEAAWRELEAERAQLQSQLQREQE 1025
Query: 246 AVLAKAKAKAEAIRILAAALTQHNGDAAASLTVAEQYVSAFSKLAKDSNTIL 297
+LA+ +A+ E + AAL Q + L +AE L + T L
Sbjct: 1026 ELLARLEAEKEELSEEIAALQQERDE---GLLLAESEKQQALSLKESEKTAL 1074
Score = 32.0 bits (71), Expect = 0.87
Identities = 41/177 (23%), Positives = 80/177 (45%), Gaps = 14/177 (7%)
Query: 129 LAQTTMRSELGKL------SLDKVFRERESLNASIVDAINQAADCWGIRCLRYEIKDIHV 182
LA+ T+ EL L + +K ++E + +V A +A + +E +D+
Sbjct: 939 LAKETLTGELAGLRQQIIATQEKASLDKELMAQKLVQAEREAQASLREQRAAHE-EDLQR 997
Query: 183 PPRVKESMQMQVEAERRKRATVLESEGTRESAINVAEGKKQ---AQILASEAEKAEQINQ 239
R KE+ ++EAER + + L+ E +E + E +K+ +I A + E+ E +
Sbjct: 998 LQREKEAAWRELEAERAQLQSQLQRE--QEELLARLEAEKEELSEEIAALQQERDEGLLL 1055
Query: 240 AAGEASAVLAKAKAKAEAIRILAAALTQHNGDAAASLTVAEQYVSAFSKLAKDSNTI 296
A E L+ +++ A+ + + A SL + Q A S+ +D +T+
Sbjct: 1056 AESEKQQALSLKESEKTALS--EKLMGTRHSLATISLEMERQKRDAQSRQEQDRSTV 1110
>gi|237858619 polyamine modulated factor 1 binding protein 1 isoform
a [Homo sapiens]
Length = 1007
Score = 34.7 bits (78), Expect = 0.13
Identities = 34/145 (23%), Positives = 57/145 (39%), Gaps = 30/145 (20%)
Query: 148 RERESLNASIVDAINQAADCWGIRCLRYEIKDIHVPPRVKESMQMQVEAERRKRATVLES 207
RE SLN+ ++ L+ +IK++H + +R+R T+ ++
Sbjct: 10 REVSSLNSKLLS-------------LQLDIKNLH-------------DVCKRQRKTLQDN 43
Query: 208 EGTRESAINVAEGKKQAQILASEAEKAEQINQAAGEASAVLAKAKAKAEAIRILAAALTQ 267
+ E A+N + KKQAQ LA E + E L + + + + +L L
Sbjct: 44 QLCMEEAMNSSHDKKQAQALAFEESEVE----FGSSKQCHLRQLQQLKKKLLVLQQELEF 99
Query: 268 HNGDAAASLTVAEQYVSAFSKLAKD 292
H + S QY S K D
Sbjct: 100 HTEELQTSYYSLRQYQSILEKQTSD 124
>gi|153791662 coiled-coil domain containing 71 [Homo sapiens]
Length = 467
Score = 34.3 bits (77), Expect = 0.18
Identities = 25/62 (40%), Positives = 32/62 (51%), Gaps = 2/62 (3%)
Query: 210 TRESAINVAEGKKQAQILASEAEKAEQINQAAGEASAVLAKAKAKAEAIRILA-AALTQH 268
T+ A K AQ+ A KA Q+ +A + A AKAKAKA+A+R A A TQ
Sbjct: 302 TQAKAAKARAKAKAAQVKAKAKAKAAQV-KAKAKVMAAWAKAKAKAKAVRAKAKVARTQP 360
Query: 269 NG 270
G
Sbjct: 361 RG 362
Score = 28.5 bits (62), Expect = 9.6
Identities = 20/57 (35%), Positives = 29/57 (50%), Gaps = 1/57 (1%)
Query: 209 GTRESAINVAEG-KKQAQILASEAEKAEQINQAAGEASAVLAKAKAKAEAIRILAAA 264
GT+ + VA K A+ A A + +A +A A KAKAKA+A ++ A A
Sbjct: 277 GTKTAQAKVARTLAKAARAQAKVARTQAKAAKARAKAKAAQVKAKAKAKAAQVKAKA 333
>gi|48762942 huntingtin interacting protein-1-related [Homo sapiens]
Length = 1068
Score = 33.9 bits (76), Expect = 0.23
Identities = 28/104 (26%), Positives = 48/104 (46%), Gaps = 4/104 (3%)
Query: 185 RVKESMQMQVEAERRKRATVLESEGTRESAINVAEGKKQAQILASEAEKAEQINQAAGEA 244
RVKE + QVE +R+ LE + + + E + +A LA E Q+ E
Sbjct: 487 RVKEQLAFQVEQVKRESELKLEEKSDQLEKLK-RELEAKAGELARAQEALSHTEQSKSEL 545
Query: 245 SAVLAKAKAKAEAIRILAAALTQHNGDAAASLTVAEQYVSAFSK 288
S+ L A+ +A L+ A+ Q D A+ ++ + +A S+
Sbjct: 546 SSRLDTLSAEKDA---LSGAVRQREADLLAAQSLVRETEAALSR 586
Score = 28.5 bits (62), Expect = 9.6
Identities = 21/87 (24%), Positives = 38/87 (43%), Gaps = 3/87 (3%)
Query: 195 EAERRKRATVLESEGTRESAINVAEGKKQAQILASEAEKAEQINQAAGEASAVLAKAKAK 254
E ++K+ ++++E R + + + + E+AE+ A A K K K
Sbjct: 397 EQRKQKQKALVDNEQLRHELAQLRAAQLEGERSQGLREEAER---KASATEARYNKLKEK 453
Query: 255 AEAIRILAAALTQHNGDAAASLTVAEQ 281
+ + A L + N D A LTV +Q
Sbjct: 454 HSELVHVHAELLRKNADTAKQLTVTQQ 480
>gi|21735548 centrosomal protein 2 [Homo sapiens]
Length = 2442
Score = 33.9 bits (76), Expect = 0.23
Identities = 32/133 (24%), Positives = 67/133 (50%), Gaps = 7/133 (5%)
Query: 137 ELGKLSLDKVFRERESLNASIVDAINQAADCWGIRCLRYEIKDIHVPPRVKESMQMQVEA 196
EL + + + + + E L A++V+A QA+ GI L +++ ++K +VE+
Sbjct: 1344 ELLQAAKENLTAQVEHLQAAVVEARAQASAA-GI--LEEDLRTARSALKLKNE---EVES 1397
Query: 197 ERRKRATVLESEGTRESAINVAEGKKQAQILASEAEKAEQINQAAGEASAVLAKAKAKAE 256
ER +RA L+ +G + A A + A + + AE+ E++ G+ + + + +
Sbjct: 1398 ER-ERAQALQEQGELKVAQGKALQENLALLTQTLAEREEEVETLRGQIQELEKQREMQKA 1456
Query: 257 AIRILAAALTQHN 269
A+ +L+ L + N
Sbjct: 1457 ALELLSLDLKKRN 1469
Score = 29.6 bits (65), Expect = 4.3
Identities = 40/171 (23%), Positives = 72/171 (42%), Gaps = 37/171 (21%)
Query: 143 LDKVFRERESLNASIVDAINQAADCWGIRCLRYEIKDIHVPPRVKESMQMQVEAERRKRA 202
L K+ ER++L VD L+ E+ + + +E +Q E E R++
Sbjct: 437 LQKLTGERDTLAGQTVD-------------LQGEVDSLS---KERELLQKARE-ELRQQL 479
Query: 203 TVLESEGTRESAINV--------AEGKKQAQ-----ILASEAEKAEQ----INQAAGEAS 245
VLE E R +NV A+G+K+ Q + E E+ ++ + E+
Sbjct: 480 EVLEQEAWRLRRVNVELQLQGDSAQGQKEEQQEELHLAVRERERLQEMLMGLEAKQSESL 539
Query: 246 AVLAKAKAKAEAIRILAAALTQHNGDAAASLTVAEQYVSAFSKLAKDSNTI 296
+ L + E+ + L Q + A+L AEQ + ++L+ NT+
Sbjct: 540 SELITLREALESSHLEGELLRQEQTEVTAALARAEQ---SIAELSSSENTL 587
>gi|239750456 PREDICTED: similar to KIAA0655 protein [Homo sapiens]
Length = 1048
Score = 33.9 bits (76), Expect = 0.23
Identities = 28/104 (26%), Positives = 48/104 (46%), Gaps = 4/104 (3%)
Query: 185 RVKESMQMQVEAERRKRATVLESEGTRESAINVAEGKKQAQILASEAEKAEQINQAAGEA 244
RVKE + QVE +R+ LE + + + E + +A LA E Q+ E
Sbjct: 467 RVKEQLAFQVEQVKRESELKLEEKSDQLEKLK-RELEAKAGELARAQEALSHTEQSKSEL 525
Query: 245 SAVLAKAKAKAEAIRILAAALTQHNGDAAASLTVAEQYVSAFSK 288
S+ L A+ +A L+ A+ Q D A+ ++ + +A S+
Sbjct: 526 SSRLDTLSAEKDA---LSGAVRQREADLLAAQSLVRETEAALSR 566
Score = 28.5 bits (62), Expect = 9.6
Identities = 21/87 (24%), Positives = 38/87 (43%), Gaps = 3/87 (3%)
Query: 195 EAERRKRATVLESEGTRESAINVAEGKKQAQILASEAEKAEQINQAAGEASAVLAKAKAK 254
E ++K+ ++++E R + + + + E+AE+ A A K K K
Sbjct: 377 EQRKQKQKALVDNEQLRHELAQLRAAQLEGERSQGLREEAER---KASATEARYNKLKEK 433
Query: 255 AEAIRILAAALTQHNGDAAASLTVAEQ 281
+ + A L + N D A LTV +Q
Sbjct: 434 HSELVHVHAELLRKNADTAKQLTVTQQ 460
>gi|153945790 myosin, heavy chain 8, skeletal muscle, perinatal [Homo
sapiens]
Length = 1937
Score = 33.9 bits (76), Expect = 0.23
Identities = 40/209 (19%), Positives = 89/209 (42%), Gaps = 36/209 (17%)
Query: 74 RYVQSLKEIVINVPEQSAV--TLDNVTLQIDGVLYLRIMDPYKASYGVEDPEYAVTQLAQ 131
R +++++++V +A LD D +++ +K Y E +Q
Sbjct: 1423 RLQNEVEDLMLDVERSNAACAALDKKQRNFD-----KVLSEWKQKYEETQAELEASQKES 1477
Query: 132 TTMRSELGKLS---------LDKVFRERESLNASIVDAINQAADCWGIRCLRYEIKDIHV 182
++ +EL K+ L+ + RE ++L I D Q A+ K IH
Sbjct: 1478 RSLSTELFKVKNVYEESLDQLETLRRENKNLQQEISDLTEQIAEGG---------KQIHE 1528
Query: 183 PPRVKESMQMQ---VEAERRKRATVLESEGTRESAINVAEGKKQAQILASEAEKAEQINQ 239
++K+ ++ + ++A + LE E + I + + ++++ AEK E+I+Q
Sbjct: 1529 LEKIKKQVEQEKCEIQAALEEAEASLEHEEGKILRIQLELNQVKSEVDRKIAEKDEEIDQ 1588
Query: 240 AAGEASAVL--------AKAKAKAEAIRI 260
+ V+ A+ +++ +A+R+
Sbjct: 1589 LKRNHTRVVETMQSTLDAEIRSRNDALRV 1617
>gi|41322923 plectin 1 isoform 11 [Homo sapiens]
Length = 4547
Score = 33.5 bits (75), Expect = 0.30
Identities = 21/69 (30%), Positives = 37/69 (53%), Gaps = 7/69 (10%)
Query: 191 QMQVEAERRKRATVLESEGTRESAINVAEGKKQAQILASEAEKAEQINQAAGEASAVLAK 250
Q++ EAE +RA E ++ A+ ++Q E+AE++ Q+A E + A+
Sbjct: 2078 QLRGEAEAARRAAEEAEEARVQAEREAAQSRRQ-------VEEAERLKQSAEEQAQARAQ 2130
Query: 251 AKAKAEAIR 259
A+A AE +R
Sbjct: 2131 AQAAAEKLR 2139
Score = 33.5 bits (75), Expect = 0.30
Identities = 25/76 (32%), Positives = 40/76 (52%), Gaps = 6/76 (7%)
Query: 187 KESMQMQVEAER---RKRATVLESEGTRESAINVAEGKKQAQILASEAEK---AEQINQA 240
+E+ + +V+AER + R V E+E ++SA A+ + QAQ A + K E +A
Sbjct: 2091 EEAEEARVQAEREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRA 2150
Query: 241 AGEASAVLAKAKAKAE 256
E +A+ K A AE
Sbjct: 2151 QAEQAALRQKQAADAE 2166
Score = 32.3 bits (72), Expect = 0.67
Identities = 27/105 (25%), Positives = 48/105 (45%), Gaps = 9/105 (8%)
Query: 185 RVKESMQMQVEAERRKRATVLESEGTRESAINVA--------EGKKQAQILASEAEKAEQ 236
RV++S+ + EA R+++A + E E + E +Q Q+ A+K Q
Sbjct: 1989 RVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAEQESARQLQLAQEAAQKRLQ 2048
Query: 237 INQAAGEASAVLAKAKAKAEAIRILAAALTQHNGDAAASLTVAEQ 281
+ A A AV K + + ++ + L Q G+A A+ AE+
Sbjct: 2049 AEEKA-HAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEE 2092
Score = 31.2 bits (69), Expect = 1.5
Identities = 28/93 (30%), Positives = 42/93 (45%), Gaps = 6/93 (6%)
Query: 188 ESMQMQVEAERRKRATVLESEGTRESAINVAEGKKQAQILASEAEKA----EQINQAAGE 243
+ Q Q EAER +R ES+ R++ + +A K A E ++A E++ A E
Sbjct: 1488 QKRQAQEEAERLRRQVQDESQRKRQAEVELASRVKAEAEAAREKQRALQALEELRLQAEE 1547
Query: 244 ASAVLAKAKAKAEAIRILAAALTQHNGDAAASL 276
A L +A+ E R + AL A A L
Sbjct: 1548 AERRL--RQAEVERARQVQVALETAQRSAEAEL 1578
Score = 28.5 bits (62), Expect = 9.6
Identities = 25/93 (26%), Positives = 43/93 (46%), Gaps = 2/93 (2%)
Query: 195 EAERRKRATVLESEGTRESAINVAEGKKQAQI-LASEAEKAEQINQAAGEASAVLAKAKA 253
EAE +KR E+E R + ++ K+QA++ LAS + + + A L + +
Sbjct: 1484 EAEAQKRQAQEEAERLRRQVQDESQRKRQAEVELASRVKAEAEAAREKQRALQALEELRL 1543
Query: 254 KA-EAIRILAAALTQHNGDAAASLTVAEQYVSA 285
+A EA R L A + +L A++ A
Sbjct: 1544 QAEEAERRLRQAEVERARQVQVALETAQRSAEA 1576
>gi|41322914 plectin 1 isoform 10 [Homo sapiens]
Length = 4551
Score = 33.5 bits (75), Expect = 0.30
Identities = 21/69 (30%), Positives = 37/69 (53%), Gaps = 7/69 (10%)
Query: 191 QMQVEAERRKRATVLESEGTRESAINVAEGKKQAQILASEAEKAEQINQAAGEASAVLAK 250
Q++ EAE +RA E ++ A+ ++Q E+AE++ Q+A E + A+
Sbjct: 2082 QLRGEAEAARRAAEEAEEARVQAEREAAQSRRQ-------VEEAERLKQSAEEQAQARAQ 2134
Query: 251 AKAKAEAIR 259
A+A AE +R
Sbjct: 2135 AQAAAEKLR 2143
Score = 33.5 bits (75), Expect = 0.30
Identities = 25/76 (32%), Positives = 40/76 (52%), Gaps = 6/76 (7%)
Query: 187 KESMQMQVEAER---RKRATVLESEGTRESAINVAEGKKQAQILASEAEK---AEQINQA 240
+E+ + +V+AER + R V E+E ++SA A+ + QAQ A + K E +A
Sbjct: 2095 EEAEEARVQAEREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRA 2154
Query: 241 AGEASAVLAKAKAKAE 256
E +A+ K A AE
Sbjct: 2155 QAEQAALRQKQAADAE 2170
Score = 32.3 bits (72), Expect = 0.67
Identities = 27/105 (25%), Positives = 48/105 (45%), Gaps = 9/105 (8%)
Query: 185 RVKESMQMQVEAERRKRATVLESEGTRESAINVA--------EGKKQAQILASEAEKAEQ 236
RV++S+ + EA R+++A + E E + E +Q Q+ A+K Q
Sbjct: 1993 RVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAEQESARQLQLAQEAAQKRLQ 2052
Query: 237 INQAAGEASAVLAKAKAKAEAIRILAAALTQHNGDAAASLTVAEQ 281
+ A A AV K + + ++ + L Q G+A A+ AE+
Sbjct: 2053 AEEKA-HAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEE 2096
Score = 31.2 bits (69), Expect = 1.5
Identities = 28/93 (30%), Positives = 42/93 (45%), Gaps = 6/93 (6%)
Query: 188 ESMQMQVEAERRKRATVLESEGTRESAINVAEGKKQAQILASEAEKA----EQINQAAGE 243
+ Q Q EAER +R ES+ R++ + +A K A E ++A E++ A E
Sbjct: 1492 QKRQAQEEAERLRRQVQDESQRKRQAEVELASRVKAEAEAAREKQRALQALEELRLQAEE 1551
Query: 244 ASAVLAKAKAKAEAIRILAAALTQHNGDAAASL 276
A L +A+ E R + AL A A L
Sbjct: 1552 AERRL--RQAEVERARQVQVALETAQRSAEAEL 1582
Score = 28.5 bits (62), Expect = 9.6
Identities = 25/93 (26%), Positives = 43/93 (46%), Gaps = 2/93 (2%)
Query: 195 EAERRKRATVLESEGTRESAINVAEGKKQAQI-LASEAEKAEQINQAAGEASAVLAKAKA 253
EAE +KR E+E R + ++ K+QA++ LAS + + + A L + +
Sbjct: 1488 EAEAQKRQAQEEAERLRRQVQDESQRKRQAEVELASRVKAEAEAAREKQRALQALEELRL 1547
Query: 254 KA-EAIRILAAALTQHNGDAAASLTVAEQYVSA 285
+A EA R L A + +L A++ A
Sbjct: 1548 QAEEAERRLRQAEVERARQVQVALETAQRSAEA 1580
>gi|41322919 plectin 1 isoform 8 [Homo sapiens]
Length = 4547
Score = 33.5 bits (75), Expect = 0.30
Identities = 21/69 (30%), Positives = 37/69 (53%), Gaps = 7/69 (10%)
Query: 191 QMQVEAERRKRATVLESEGTRESAINVAEGKKQAQILASEAEKAEQINQAAGEASAVLAK 250
Q++ EAE +RA E ++ A+ ++Q E+AE++ Q+A E + A+
Sbjct: 2078 QLRGEAEAARRAAEEAEEARVQAEREAAQSRRQ-------VEEAERLKQSAEEQAQARAQ 2130
Query: 251 AKAKAEAIR 259
A+A AE +R
Sbjct: 2131 AQAAAEKLR 2139
Score = 33.5 bits (75), Expect = 0.30
Identities = 25/76 (32%), Positives = 40/76 (52%), Gaps = 6/76 (7%)
Query: 187 KESMQMQVEAER---RKRATVLESEGTRESAINVAEGKKQAQILASEAEK---AEQINQA 240
+E+ + +V+AER + R V E+E ++SA A+ + QAQ A + K E +A
Sbjct: 2091 EEAEEARVQAEREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRA 2150
Query: 241 AGEASAVLAKAKAKAE 256
E +A+ K A AE
Sbjct: 2151 QAEQAALRQKQAADAE 2166
Score = 32.3 bits (72), Expect = 0.67
Identities = 27/105 (25%), Positives = 48/105 (45%), Gaps = 9/105 (8%)
Query: 185 RVKESMQMQVEAERRKRATVLESEGTRESAINVA--------EGKKQAQILASEAEKAEQ 236
RV++S+ + EA R+++A + E E + E +Q Q+ A+K Q
Sbjct: 1989 RVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAEQESARQLQLAQEAAQKRLQ 2048
Query: 237 INQAAGEASAVLAKAKAKAEAIRILAAALTQHNGDAAASLTVAEQ 281
+ A A AV K + + ++ + L Q G+A A+ AE+
Sbjct: 2049 AEEKA-HAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEE 2092
Score = 31.2 bits (69), Expect = 1.5
Identities = 28/93 (30%), Positives = 42/93 (45%), Gaps = 6/93 (6%)
Query: 188 ESMQMQVEAERRKRATVLESEGTRESAINVAEGKKQAQILASEAEKA----EQINQAAGE 243
+ Q Q EAER +R ES+ R++ + +A K A E ++A E++ A E
Sbjct: 1488 QKRQAQEEAERLRRQVQDESQRKRQAEVELASRVKAEAEAAREKQRALQALEELRLQAEE 1547
Query: 244 ASAVLAKAKAKAEAIRILAAALTQHNGDAAASL 276
A L +A+ E R + AL A A L
Sbjct: 1548 AERRL--RQAEVERARQVQVALETAQRSAEAEL 1578
Score = 28.5 bits (62), Expect = 9.6
Identities = 25/93 (26%), Positives = 43/93 (46%), Gaps = 2/93 (2%)
Query: 195 EAERRKRATVLESEGTRESAINVAEGKKQAQI-LASEAEKAEQINQAAGEASAVLAKAKA 253
EAE +KR E+E R + ++ K+QA++ LAS + + + A L + +
Sbjct: 1484 EAEAQKRQAQEEAERLRRQVQDESQRKRQAEVELASRVKAEAEAAREKQRALQALEELRL 1543
Query: 254 KA-EAIRILAAALTQHNGDAAASLTVAEQYVSA 285
+A EA R L A + +L A++ A
Sbjct: 1544 QAEEAERRLRQAEVERARQVQVALETAQRSAEA 1576
>gi|41322910 plectin 1 isoform 7 [Homo sapiens]
Length = 4515
Score = 33.5 bits (75), Expect = 0.30
Identities = 21/69 (30%), Positives = 37/69 (53%), Gaps = 7/69 (10%)
Query: 191 QMQVEAERRKRATVLESEGTRESAINVAEGKKQAQILASEAEKAEQINQAAGEASAVLAK 250
Q++ EAE +RA E ++ A+ ++Q E+AE++ Q+A E + A+
Sbjct: 2046 QLRGEAEAARRAAEEAEEARVQAEREAAQSRRQ-------VEEAERLKQSAEEQAQARAQ 2098
Query: 251 AKAKAEAIR 259
A+A AE +R
Sbjct: 2099 AQAAAEKLR 2107
Score = 33.5 bits (75), Expect = 0.30
Identities = 25/76 (32%), Positives = 40/76 (52%), Gaps = 6/76 (7%)
Query: 187 KESMQMQVEAER---RKRATVLESEGTRESAINVAEGKKQAQILASEAEK---AEQINQA 240
+E+ + +V+AER + R V E+E ++SA A+ + QAQ A + K E +A
Sbjct: 2059 EEAEEARVQAEREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRA 2118
Query: 241 AGEASAVLAKAKAKAE 256
E +A+ K A AE
Sbjct: 2119 QAEQAALRQKQAADAE 2134
Score = 32.3 bits (72), Expect = 0.67
Identities = 27/105 (25%), Positives = 48/105 (45%), Gaps = 9/105 (8%)
Query: 185 RVKESMQMQVEAERRKRATVLESEGTRESAINVA--------EGKKQAQILASEAEKAEQ 236
RV++S+ + EA R+++A + E E + E +Q Q+ A+K Q
Sbjct: 1957 RVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAEQESARQLQLAQEAAQKRLQ 2016
Query: 237 INQAAGEASAVLAKAKAKAEAIRILAAALTQHNGDAAASLTVAEQ 281
+ A A AV K + + ++ + L Q G+A A+ AE+
Sbjct: 2017 AEEKA-HAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEE 2060
Score = 31.2 bits (69), Expect = 1.5
Identities = 28/93 (30%), Positives = 42/93 (45%), Gaps = 6/93 (6%)
Query: 188 ESMQMQVEAERRKRATVLESEGTRESAINVAEGKKQAQILASEAEKA----EQINQAAGE 243
+ Q Q EAER +R ES+ R++ + +A K A E ++A E++ A E
Sbjct: 1456 QKRQAQEEAERLRRQVQDESQRKRQAEVELASRVKAEAEAAREKQRALQALEELRLQAEE 1515
Query: 244 ASAVLAKAKAKAEAIRILAAALTQHNGDAAASL 276
A L +A+ E R + AL A A L
Sbjct: 1516 AERRL--RQAEVERARQVQVALETAQRSAEAEL 1546
Score = 28.5 bits (62), Expect = 9.6
Identities = 25/93 (26%), Positives = 43/93 (46%), Gaps = 2/93 (2%)
Query: 195 EAERRKRATVLESEGTRESAINVAEGKKQAQI-LASEAEKAEQINQAAGEASAVLAKAKA 253
EAE +KR E+E R + ++ K+QA++ LAS + + + A L + +
Sbjct: 1452 EAEAQKRQAQEEAERLRRQVQDESQRKRQAEVELASRVKAEAEAAREKQRALQALEELRL 1511
Query: 254 KA-EAIRILAAALTQHNGDAAASLTVAEQYVSA 285
+A EA R L A + +L A++ A
Sbjct: 1512 QAEEAERRLRQAEVERARQVQVALETAQRSAEA 1544
>gi|41322916 plectin 1 isoform 6 [Homo sapiens]
Length = 4684
Score = 33.5 bits (75), Expect = 0.30
Identities = 21/69 (30%), Positives = 37/69 (53%), Gaps = 7/69 (10%)
Query: 191 QMQVEAERRKRATVLESEGTRESAINVAEGKKQAQILASEAEKAEQINQAAGEASAVLAK 250
Q++ EAE +RA E ++ A+ ++Q E+AE++ Q+A E + A+
Sbjct: 2215 QLRGEAEAARRAAEEAEEARVQAEREAAQSRRQ-------VEEAERLKQSAEEQAQARAQ 2267
Query: 251 AKAKAEAIR 259
A+A AE +R
Sbjct: 2268 AQAAAEKLR 2276
Score = 33.5 bits (75), Expect = 0.30
Identities = 25/76 (32%), Positives = 40/76 (52%), Gaps = 6/76 (7%)
Query: 187 KESMQMQVEAER---RKRATVLESEGTRESAINVAEGKKQAQILASEAEK---AEQINQA 240
+E+ + +V+AER + R V E+E ++SA A+ + QAQ A + K E +A
Sbjct: 2228 EEAEEARVQAEREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRA 2287
Query: 241 AGEASAVLAKAKAKAE 256
E +A+ K A AE
Sbjct: 2288 QAEQAALRQKQAADAE 2303
Score = 32.3 bits (72), Expect = 0.67
Identities = 27/105 (25%), Positives = 48/105 (45%), Gaps = 9/105 (8%)
Query: 185 RVKESMQMQVEAERRKRATVLESEGTRESAINVA--------EGKKQAQILASEAEKAEQ 236
RV++S+ + EA R+++A + E E + E +Q Q+ A+K Q
Sbjct: 2126 RVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAEQESARQLQLAQEAAQKRLQ 2185
Query: 237 INQAAGEASAVLAKAKAKAEAIRILAAALTQHNGDAAASLTVAEQ 281
+ A A AV K + + ++ + L Q G+A A+ AE+
Sbjct: 2186 AEEKA-HAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEE 2229
Score = 31.2 bits (69), Expect = 1.5
Identities = 28/93 (30%), Positives = 42/93 (45%), Gaps = 6/93 (6%)
Query: 188 ESMQMQVEAERRKRATVLESEGTRESAINVAEGKKQAQILASEAEKA----EQINQAAGE 243
+ Q Q EAER +R ES+ R++ + +A K A E ++A E++ A E
Sbjct: 1625 QKRQAQEEAERLRRQVQDESQRKRQAEVELASRVKAEAEAAREKQRALQALEELRLQAEE 1684
Query: 244 ASAVLAKAKAKAEAIRILAAALTQHNGDAAASL 276
A L +A+ E R + AL A A L
Sbjct: 1685 AERRL--RQAEVERARQVQVALETAQRSAEAEL 1715
Score = 28.5 bits (62), Expect = 9.6
Identities = 25/93 (26%), Positives = 43/93 (46%), Gaps = 2/93 (2%)
Query: 195 EAERRKRATVLESEGTRESAINVAEGKKQAQI-LASEAEKAEQINQAAGEASAVLAKAKA 253
EAE +KR E+E R + ++ K+QA++ LAS + + + A L + +
Sbjct: 1621 EAEAQKRQAQEEAERLRRQVQDESQRKRQAEVELASRVKAEAEAAREKQRALQALEELRL 1680
Query: 254 KA-EAIRILAAALTQHNGDAAASLTVAEQYVSA 285
+A EA R L A + +L A++ A
Sbjct: 1681 QAEEAERRLRQAEVERARQVQVALETAQRSAEA 1713
>gi|41322908 plectin 1 isoform 3 [Homo sapiens]
Length = 4525
Score = 33.5 bits (75), Expect = 0.30
Identities = 21/69 (30%), Positives = 37/69 (53%), Gaps = 7/69 (10%)
Query: 191 QMQVEAERRKRATVLESEGTRESAINVAEGKKQAQILASEAEKAEQINQAAGEASAVLAK 250
Q++ EAE +RA E ++ A+ ++Q E+AE++ Q+A E + A+
Sbjct: 2056 QLRGEAEAARRAAEEAEEARVQAEREAAQSRRQ-------VEEAERLKQSAEEQAQARAQ 2108
Query: 251 AKAKAEAIR 259
A+A AE +R
Sbjct: 2109 AQAAAEKLR 2117
Score = 33.5 bits (75), Expect = 0.30
Identities = 25/76 (32%), Positives = 40/76 (52%), Gaps = 6/76 (7%)
Query: 187 KESMQMQVEAER---RKRATVLESEGTRESAINVAEGKKQAQILASEAEK---AEQINQA 240
+E+ + +V+AER + R V E+E ++SA A+ + QAQ A + K E +A
Sbjct: 2069 EEAEEARVQAEREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRA 2128
Query: 241 AGEASAVLAKAKAKAE 256
E +A+ K A AE
Sbjct: 2129 QAEQAALRQKQAADAE 2144
Score = 32.3 bits (72), Expect = 0.67
Identities = 27/105 (25%), Positives = 48/105 (45%), Gaps = 9/105 (8%)
Query: 185 RVKESMQMQVEAERRKRATVLESEGTRESAINVA--------EGKKQAQILASEAEKAEQ 236
RV++S+ + EA R+++A + E E + E +Q Q+ A+K Q
Sbjct: 1967 RVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAEQESARQLQLAQEAAQKRLQ 2026
Query: 237 INQAAGEASAVLAKAKAKAEAIRILAAALTQHNGDAAASLTVAEQ 281
+ A A AV K + + ++ + L Q G+A A+ AE+
Sbjct: 2027 AEEKA-HAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEE 2070
Score = 31.2 bits (69), Expect = 1.5
Identities = 28/93 (30%), Positives = 42/93 (45%), Gaps = 6/93 (6%)
Query: 188 ESMQMQVEAERRKRATVLESEGTRESAINVAEGKKQAQILASEAEKA----EQINQAAGE 243
+ Q Q EAER +R ES+ R++ + +A K A E ++A E++ A E
Sbjct: 1466 QKRQAQEEAERLRRQVQDESQRKRQAEVELASRVKAEAEAAREKQRALQALEELRLQAEE 1525
Query: 244 ASAVLAKAKAKAEAIRILAAALTQHNGDAAASL 276
A L +A+ E R + AL A A L
Sbjct: 1526 AERRL--RQAEVERARQVQVALETAQRSAEAEL 1556
Score = 28.5 bits (62), Expect = 9.6
Identities = 25/93 (26%), Positives = 43/93 (46%), Gaps = 2/93 (2%)
Query: 195 EAERRKRATVLESEGTRESAINVAEGKKQAQI-LASEAEKAEQINQAAGEASAVLAKAKA 253
EAE +KR E+E R + ++ K+QA++ LAS + + + A L + +
Sbjct: 1462 EAEAQKRQAQEEAERLRRQVQDESQRKRQAEVELASRVKAEAEAAREKQRALQALEELRL 1521
Query: 254 KA-EAIRILAAALTQHNGDAAASLTVAEQYVSA 285
+A EA R L A + +L A++ A
Sbjct: 1522 QAEEAERRLRQAEVERARQVQVALETAQRSAEA 1554
>gi|41322912 plectin 1 isoform 2 [Homo sapiens]
Length = 4533
Score = 33.5 bits (75), Expect = 0.30
Identities = 21/69 (30%), Positives = 37/69 (53%), Gaps = 7/69 (10%)
Query: 191 QMQVEAERRKRATVLESEGTRESAINVAEGKKQAQILASEAEKAEQINQAAGEASAVLAK 250
Q++ EAE +RA E ++ A+ ++Q E+AE++ Q+A E + A+
Sbjct: 2064 QLRGEAEAARRAAEEAEEARVQAEREAAQSRRQ-------VEEAERLKQSAEEQAQARAQ 2116
Query: 251 AKAKAEAIR 259
A+A AE +R
Sbjct: 2117 AQAAAEKLR 2125
Score = 33.5 bits (75), Expect = 0.30
Identities = 25/76 (32%), Positives = 40/76 (52%), Gaps = 6/76 (7%)
Query: 187 KESMQMQVEAER---RKRATVLESEGTRESAINVAEGKKQAQILASEAEK---AEQINQA 240
+E+ + +V+AER + R V E+E ++SA A+ + QAQ A + K E +A
Sbjct: 2077 EEAEEARVQAEREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRA 2136
Query: 241 AGEASAVLAKAKAKAE 256
E +A+ K A AE
Sbjct: 2137 QAEQAALRQKQAADAE 2152
Score = 32.3 bits (72), Expect = 0.67
Identities = 27/105 (25%), Positives = 48/105 (45%), Gaps = 9/105 (8%)
Query: 185 RVKESMQMQVEAERRKRATVLESEGTRESAINVA--------EGKKQAQILASEAEKAEQ 236
RV++S+ + EA R+++A + E E + E +Q Q+ A+K Q
Sbjct: 1975 RVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAEQESARQLQLAQEAAQKRLQ 2034
Query: 237 INQAAGEASAVLAKAKAKAEAIRILAAALTQHNGDAAASLTVAEQ 281
+ A A AV K + + ++ + L Q G+A A+ AE+
Sbjct: 2035 AEEKA-HAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEE 2078
Score = 31.2 bits (69), Expect = 1.5
Identities = 28/93 (30%), Positives = 42/93 (45%), Gaps = 6/93 (6%)
Query: 188 ESMQMQVEAERRKRATVLESEGTRESAINVAEGKKQAQILASEAEKA----EQINQAAGE 243
+ Q Q EAER +R ES+ R++ + +A K A E ++A E++ A E
Sbjct: 1474 QKRQAQEEAERLRRQVQDESQRKRQAEVELASRVKAEAEAAREKQRALQALEELRLQAEE 1533
Query: 244 ASAVLAKAKAKAEAIRILAAALTQHNGDAAASL 276
A L +A+ E R + AL A A L
Sbjct: 1534 AERRL--RQAEVERARQVQVALETAQRSAEAEL 1564
Score = 28.5 bits (62), Expect = 9.6
Identities = 25/93 (26%), Positives = 43/93 (46%), Gaps = 2/93 (2%)
Query: 195 EAERRKRATVLESEGTRESAINVAEGKKQAQI-LASEAEKAEQINQAAGEASAVLAKAKA 253
EAE +KR E+E R + ++ K+QA++ LAS + + + A L + +
Sbjct: 1470 EAEAQKRQAQEEAERLRRQVQDESQRKRQAEVELASRVKAEAEAAREKQRALQALEELRL 1529
Query: 254 KA-EAIRILAAALTQHNGDAAASLTVAEQYVSA 285
+A EA R L A + +L A++ A
Sbjct: 1530 QAEEAERRLRQAEVERARQVQVALETAQRSAEA 1562
>gi|47607492 plectin 1 isoform 1 [Homo sapiens]
Length = 4574
Score = 33.5 bits (75), Expect = 0.30
Identities = 21/69 (30%), Positives = 37/69 (53%), Gaps = 7/69 (10%)
Query: 191 QMQVEAERRKRATVLESEGTRESAINVAEGKKQAQILASEAEKAEQINQAAGEASAVLAK 250
Q++ EAE +RA E ++ A+ ++Q E+AE++ Q+A E + A+
Sbjct: 2105 QLRGEAEAARRAAEEAEEARVQAEREAAQSRRQ-------VEEAERLKQSAEEQAQARAQ 2157
Query: 251 AKAKAEAIR 259
A+A AE +R
Sbjct: 2158 AQAAAEKLR 2166
Score = 33.5 bits (75), Expect = 0.30
Identities = 25/76 (32%), Positives = 40/76 (52%), Gaps = 6/76 (7%)
Query: 187 KESMQMQVEAER---RKRATVLESEGTRESAINVAEGKKQAQILASEAEK---AEQINQA 240
+E+ + +V+AER + R V E+E ++SA A+ + QAQ A + K E +A
Sbjct: 2118 EEAEEARVQAEREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRA 2177
Query: 241 AGEASAVLAKAKAKAE 256
E +A+ K A AE
Sbjct: 2178 QAEQAALRQKQAADAE 2193
Score = 32.3 bits (72), Expect = 0.67
Identities = 27/105 (25%), Positives = 48/105 (45%), Gaps = 9/105 (8%)
Query: 185 RVKESMQMQVEAERRKRATVLESEGTRESAINVA--------EGKKQAQILASEAEKAEQ 236
RV++S+ + EA R+++A + E E + E +Q Q+ A+K Q
Sbjct: 2016 RVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAEQESARQLQLAQEAAQKRLQ 2075
Query: 237 INQAAGEASAVLAKAKAKAEAIRILAAALTQHNGDAAASLTVAEQ 281
+ A A AV K + + ++ + L Q G+A A+ AE+
Sbjct: 2076 AEEKA-HAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEE 2119
Score = 31.2 bits (69), Expect = 1.5
Identities = 28/93 (30%), Positives = 42/93 (45%), Gaps = 6/93 (6%)
Query: 188 ESMQMQVEAERRKRATVLESEGTRESAINVAEGKKQAQILASEAEKA----EQINQAAGE 243
+ Q Q EAER +R ES+ R++ + +A K A E ++A E++ A E
Sbjct: 1515 QKRQAQEEAERLRRQVQDESQRKRQAEVELASRVKAEAEAAREKQRALQALEELRLQAEE 1574
Query: 244 ASAVLAKAKAKAEAIRILAAALTQHNGDAAASL 276
A L +A+ E R + AL A A L
Sbjct: 1575 AERRL--RQAEVERARQVQVALETAQRSAEAEL 1605
Score = 28.5 bits (62), Expect = 9.6
Identities = 25/93 (26%), Positives = 43/93 (46%), Gaps = 2/93 (2%)
Query: 195 EAERRKRATVLESEGTRESAINVAEGKKQAQI-LASEAEKAEQINQAAGEASAVLAKAKA 253
EAE +KR E+E R + ++ K+QA++ LAS + + + A L + +
Sbjct: 1511 EAEAQKRQAQEEAERLRRQVQDESQRKRQAEVELASRVKAEAEAAREKQRALQALEELRL 1570
Query: 254 KA-EAIRILAAALTQHNGDAAASLTVAEQYVSA 285
+A EA R L A + +L A++ A
Sbjct: 1571 QAEEAERRLRQAEVERARQVQVALETAQRSAEA 1603
>gi|91208418 transcription elongation regulator 1 isoform 2 [Homo
sapiens]
Length = 1077
Score = 33.5 bits (75), Expect = 0.30
Identities = 35/142 (24%), Positives = 55/142 (38%), Gaps = 9/142 (6%)
Query: 202 ATVLESEGTRESAINVAEGKKQAQILASEAEKAEQINQAAGEASAVLAKAKAKAEAIRIL 261
A ES T+ + V + + +LA++A+ Q A + A+A+A+A+A
Sbjct: 152 ARTRESAWTKPDGVKVIQQSELTPMLAAQAQVQAQAQAQAQAQAQAQAQAQAQAQA---Q 208
Query: 262 AAALTQHNGDAAASLTVAEQYVSAFSKLAKDSNTILLPSNPGDVTSMV-AQAMGVYGALT 320
A A Q A A Q + A+ + V + V AQA+G T
Sbjct: 209 AQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQV-----QAQVQAQVQAQAVGASTPTT 263
Query: 321 KAPVPGTPDSLSSGSSRDVQGT 342
+P P S SS + T
Sbjct: 264 SSPAPAVSTSTSSSTPSSTTST 285
Score = 30.4 bits (67), Expect = 2.5
Identities = 26/125 (20%), Positives = 54/125 (43%), Gaps = 5/125 (4%)
Query: 177 IKDIHVPPRVKESMQMQVEAERRKRATVLESEGTRESAINVAEGKKQAQILASEAEKAEQ 236
I+ + P + Q+Q +A+ + +A + A A+ + QAQ A +A+
Sbjct: 168 IQQSELTPMLAAQAQVQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQA 227
Query: 237 INQAAGEASA-----VLAKAKAKAEAIRILAAALTQHNGDAAASLTVAEQYVSAFSKLAK 291
QA +A A V A+ +A+ +A + A+ T + A S + + S+ +
Sbjct: 228 QAQAQAQAQAQAQAQVQAQVQAQVQAQAVGASTPTTSSPAPAVSTSTSSSTPSSTTSTTT 287
Query: 292 DSNTI 296
+ ++
Sbjct: 288 TATSV 292
>gi|21327715 transcription elongation regulator 1 isoform 1 [Homo
sapiens]
Length = 1098
Score = 33.5 bits (75), Expect = 0.30
Identities = 35/142 (24%), Positives = 55/142 (38%), Gaps = 9/142 (6%)
Query: 202 ATVLESEGTRESAINVAEGKKQAQILASEAEKAEQINQAAGEASAVLAKAKAKAEAIRIL 261
A ES T+ + V + + +LA++A+ Q A + A+A+A+A+A
Sbjct: 152 ARTRESAWTKPDGVKVIQQSELTPMLAAQAQVQAQAQAQAQAQAQAQAQAQAQAQA---Q 208
Query: 262 AAALTQHNGDAAASLTVAEQYVSAFSKLAKDSNTILLPSNPGDVTSMV-AQAMGVYGALT 320
A A Q A A Q + A+ + V + V AQA+G T
Sbjct: 209 AQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQV-----QAQVQAQVQAQAVGASTPTT 263
Query: 321 KAPVPGTPDSLSSGSSRDVQGT 342
+P P S SS + T
Sbjct: 264 SSPAPAVSTSTSSSTPSSTTST 285
Score = 30.4 bits (67), Expect = 2.5
Identities = 26/125 (20%), Positives = 54/125 (43%), Gaps = 5/125 (4%)
Query: 177 IKDIHVPPRVKESMQMQVEAERRKRATVLESEGTRESAINVAEGKKQAQILASEAEKAEQ 236
I+ + P + Q+Q +A+ + +A + A A+ + QAQ A +A+
Sbjct: 168 IQQSELTPMLAAQAQVQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQA 227
Query: 237 INQAAGEASA-----VLAKAKAKAEAIRILAAALTQHNGDAAASLTVAEQYVSAFSKLAK 291
QA +A A V A+ +A+ +A + A+ T + A S + + S+ +
Sbjct: 228 QAQAQAQAQAQAQAQVQAQVQAQVQAQAVGASTPTTSSPAPAVSTSTSSSTPSSTTSTTT 287
Query: 292 DSNTI 296
+ ++
Sbjct: 288 TATSV 292
>gi|56961680 coiled-coil domain containing 147 [Homo sapiens]
Length = 872
Score = 31.6 bits (70), Expect = 1.1
Identities = 22/102 (21%), Positives = 48/102 (47%), Gaps = 5/102 (4%)
Query: 135 RSELGKLSLDKVFRERESLNASIVDAINQAADCWGIRCLRYEIKDIHVPPRVKESMQMQV 194
++EL + ++D++ RER+ LN +++ A+N + L + K ++ +Q
Sbjct: 371 QAELDRKAMDELLRERDILNKNMLKAVNATQKQTDLVKLHEQAK-----RNLEGEIQNYK 425
Query: 195 EAERRKRATVLESEGTRESAINVAEGKKQAQILASEAEKAEQ 236
+ +++R + E R+ IN A Q ++ E K +
Sbjct: 426 DEAQKQRKIIFHLEKERDRYINQASDLTQKVLMNMEDIKVRE 467
>gi|4507877 vinculin isoform VCL [Homo sapiens]
Length = 1066
Score = 31.2 bits (69), Expect = 1.5
Identities = 25/95 (26%), Positives = 44/95 (46%), Gaps = 11/95 (11%)
Query: 208 EGTRESAINVAEGKKQAQILASEAEKAEQINQAAGEASAVLAKAKAKAEAIRILAAALTQ 267
EG + +AE +K A+ L + ++ + I ++ GE SA+ +K LA Q
Sbjct: 403 EGEEQIRGALAEARKIAE-LCDDPKERDDILRSLGEISALTSK----------LADLRRQ 451
Query: 268 HNGDAAASLTVAEQYVSAFSKLAKDSNTILLPSNP 302
GD+ + +A+Q +A L +N + S P
Sbjct: 452 GKGDSPEARALAKQVATALQNLQTKTNRAVANSRP 486
>gi|7669550 vinculin isoform meta-VCL [Homo sapiens]
Length = 1134
Score = 31.2 bits (69), Expect = 1.5
Identities = 25/95 (26%), Positives = 44/95 (46%), Gaps = 11/95 (11%)
Query: 208 EGTRESAINVAEGKKQAQILASEAEKAEQINQAAGEASAVLAKAKAKAEAIRILAAALTQ 267
EG + +AE +K A+ L + ++ + I ++ GE SA+ +K LA Q
Sbjct: 403 EGEEQIRGALAEARKIAE-LCDDPKERDDILRSLGEISALTSK----------LADLRRQ 451
Query: 268 HNGDAAASLTVAEQYVSAFSKLAKDSNTILLPSNP 302
GD+ + +A+Q +A L +N + S P
Sbjct: 452 GKGDSPEARALAKQVATALQNLQTKTNRAVANSRP 486
>gi|122937195 plasma membrane associated protein, S3-12 [Homo
sapiens]
Length = 1357
Score = 30.8 bits (68), Expect = 1.9
Identities = 36/150 (24%), Positives = 58/150 (38%), Gaps = 8/150 (5%)
Query: 213 SAINVAEGKKQAQILASEAEKAEQINQ-AAGEASAVLAKAKAKAEAIRILAAALTQHNGD 271
SA+NVA+G Q + ++ N +G SAV A + LT
Sbjct: 626 SAVNVAKGAVQTGLKTTQNIATGTKNTFGSGVTSAVNVAKGAAQTGVDTAKTVLTGTKDT 685
Query: 272 AAASLTVAEQYVSAFSKLAKDSNTILLPSNPGDVTSMVAQAMGVY-GAL------TKAPV 324
L A + + D+ +L V S V A V GA+ TK+ +
Sbjct: 686 VTTGLMGAVNVAKGTVQTSVDTTKTVLTGTKDTVCSGVTGAANVAKGAIQGGLDTTKSVL 745
Query: 325 PGTPDSLSSGSSRDVQGTDASLDEELDRVK 354
GT D++S+G + V+ ++ +D K
Sbjct: 746 TGTKDAVSTGLTGAVKLAKGTVQTGMDTTK 775
>gi|7657455 pescadillo homolog 1, containing BRCT domain [Homo
sapiens]
Length = 588
Score = 30.4 bits (67), Expect = 2.5
Identities = 21/83 (25%), Positives = 38/83 (45%), Gaps = 2/83 (2%)
Query: 175 YEIKDIHVPPRVKESMQMQVEAERRKRATVLESEGTRESAINVAEGKKQAQILASEAEKA 234
Y++ ++H PP+++ Q Q EA+ + L+SE E ++ + + A+E E
Sbjct: 239 YQLLNLHYPPKLEG--QAQAEAKAGEGTYALDSESCMEKLAALSASLARVVVPATEEEAE 296
Query: 235 EQINQAAGEASAVLAKAKAKAEA 257
GE SA + + EA
Sbjct: 297 VDEFPTDGEMSAQEEDRRKELEA 319
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.314 0.129 0.348
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 11,260,983
Number of Sequences: 37866
Number of extensions: 447774
Number of successful extensions: 2043
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 23
Number of HSP's successfully gapped in prelim test: 52
Number of HSP's that attempted gapping in prelim test: 1849
Number of HSP's gapped (non-prelim): 219
length of query: 356
length of database: 18,247,518
effective HSP length: 103
effective length of query: 253
effective length of database: 14,347,320
effective search space: 3629871960
effective search space used: 3629871960
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.