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Search of human proteins with 72534686
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|72534686 Huntingtin interacting protein C isoform 1 [Homo
sapiens]
(871 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|72534686 Huntingtin interacting protein C isoform 1 [Homo sap... 1770 0.0
gi|29789008 Huntingtin interacting protein C isoform 2 [Homo sap... 1733 0.0
gi|151301228 formin binding protein 3 [Homo sapiens] 961 0.0
gi|91208418 transcription elongation regulator 1 isoform 2 [Homo... 140 5e-33
gi|21327715 transcription elongation regulator 1 isoform 1 [Homo... 132 1e-30
gi|155030232 proline, glutamic acid and leucine rich protein 1 [... 73 1e-12
gi|148746195 trichohyalin [Homo sapiens] 72 2e-12
gi|55741709 RNA binding motif protein 25 [Homo sapiens] 72 3e-12
gi|224451135 splicing factor, arginine/serine-rich 15 isoform 3 ... 69 2e-11
gi|148727264 transcription elongation regulator 1-like [Homo sap... 68 3e-11
gi|7706501 WW domain binding protein 11 [Homo sapiens] 67 7e-11
gi|224451133 splicing factor, arginine/serine-rich 15 isoform 2 ... 66 2e-10
gi|40789229 splicing factor, arginine/serine-rich 15 isoform 1 [... 66 2e-10
gi|146134388 YLP motif containing 1 [Homo sapiens] 65 2e-10
gi|7662046 myeloid/lymphoid or mixed-lineage leukemia 4 [Homo sa... 63 1e-09
gi|4508017 zinc finger protein 207 isoform a [Homo sapiens] 62 2e-09
gi|157168329 formin 1 [Homo sapiens] 61 4e-09
gi|160707881 formin 2 [Homo sapiens] 61 5e-09
gi|119395760 diaphanous 1 isoform 2 [Homo sapiens] 60 7e-09
gi|119395758 diaphanous 1 isoform 1 [Homo sapiens] 60 7e-09
gi|162329583 cleavage and polyadenylation specific factor 6, 68 ... 60 7e-09
gi|239754327 PREDICTED: chromosome 6 open reading frame 132 [Hom... 60 9e-09
gi|239748855 PREDICTED: chromosome 6 open reading frame 132 [Hom... 60 9e-09
gi|239742884 PREDICTED: hypothetical protein LOC647024 [Homo sap... 60 9e-09
gi|6005948 WW domain-containing binding protein 4 [Homo sapiens] 60 9e-09
gi|11386183 WAS protein family, member 2 [Homo sapiens] 59 1e-08
gi|150170670 piccolo isoform 2 [Homo sapiens] 59 1e-08
gi|150378539 piccolo isoform 1 [Homo sapiens] 59 1e-08
gi|55749531 splicing factor 3B subunit 2 [Homo sapiens] 59 1e-08
gi|156766047 GRB10 interacting GYF protein 2 isoform c [Homo sap... 58 4e-08
>gi|72534686 Huntingtin interacting protein C isoform 1 [Homo
sapiens]
Length = 871
Score = 1770 bits (4585), Expect = 0.0
Identities = 871/871 (100%), Positives = 871/871 (100%)
Query: 1 MMPPPFMPPPGIPPPFPPMGLPPMSQRPPAIPPMPPGILPPMLPPMGAPPPLTQIPGMVP 60
MMPPPFMPPPGIPPPFPPMGLPPMSQRPPAIPPMPPGILPPMLPPMGAPPPLTQIPGMVP
Sbjct: 1 MMPPPFMPPPGIPPPFPPMGLPPMSQRPPAIPPMPPGILPPMLPPMGAPPPLTQIPGMVP 60
Query: 61 PMMPGMLMPAVPVTAATAPGADTASSAVAGTGPPRALWSEHVAPDGRIYYYNADDKQSVW 120
PMMPGMLMPAVPVTAATAPGADTASSAVAGTGPPRALWSEHVAPDGRIYYYNADDKQSVW
Sbjct: 61 PMMPGMLMPAVPVTAATAPGADTASSAVAGTGPPRALWSEHVAPDGRIYYYNADDKQSVW 120
Query: 121 EKPSVLKSKAELLLSQCPWKEYKSDTGKPYYYNNQSKESRWTRPKDLDDLEVLVKQEAAG 180
EKPSVLKSKAELLLSQCPWKEYKSDTGKPYYYNNQSKESRWTRPKDLDDLEVLVKQEAAG
Sbjct: 121 EKPSVLKSKAELLLSQCPWKEYKSDTGKPYYYNNQSKESRWTRPKDLDDLEVLVKQEAAG 180
Query: 181 KQQQQLPQTLQPQPPQPQPDPPPVPPGPTPVPTGLLEPEPGGSEDCDVLEATQPLEQGFL 240
KQQQQLPQTLQPQPPQPQPDPPPVPPGPTPVPTGLLEPEPGGSEDCDVLEATQPLEQGFL
Sbjct: 181 KQQQQLPQTLQPQPPQPQPDPPPVPPGPTPVPTGLLEPEPGGSEDCDVLEATQPLEQGFL 240
Query: 241 QQLEEGPSSSGQHQPQQEEEESKPEPERSGLSWSNREKAKQAFKELLRDKAVPSNASWEQ 300
QQLEEGPSSSGQHQPQQEEEESKPEPERSGLSWSNREKAKQAFKELLRDKAVPSNASWEQ
Sbjct: 241 QQLEEGPSSSGQHQPQQEEEESKPEPERSGLSWSNREKAKQAFKELLRDKAVPSNASWEQ 300
Query: 301 AMKMVVTDPRYSALPKLSEKKQAFNAYKAQREKEEKEEARLRAKEAKQTLQHFLEQHERM 360
AMKMVVTDPRYSALPKLSEKKQAFNAYKAQREKEEKEEARLRAKEAKQTLQHFLEQHERM
Sbjct: 301 AMKMVVTDPRYSALPKLSEKKQAFNAYKAQREKEEKEEARLRAKEAKQTLQHFLEQHERM 360
Query: 361 TSTTRYRRAEQTFGELEVWAVVPERDRKEVYDDVLFFLAKKEKEQAKQLRRRNIQALKSI 420
TSTTRYRRAEQTFGELEVWAVVPERDRKEVYDDVLFFLAKKEKEQAKQLRRRNIQALKSI
Sbjct: 361 TSTTRYRRAEQTFGELEVWAVVPERDRKEVYDDVLFFLAKKEKEQAKQLRRRNIQALKSI 420
Query: 421 LDGMSSVNFQTTWSQAQQYLMDNPSFAQDHQLQNMDKEDALICFEEHIRALEREEEEERE 480
LDGMSSVNFQTTWSQAQQYLMDNPSFAQDHQLQNMDKEDALICFEEHIRALEREEEEERE
Sbjct: 421 LDGMSSVNFQTTWSQAQQYLMDNPSFAQDHQLQNMDKEDALICFEEHIRALEREEEEERE 480
Query: 481 RARLRERRQQRKNREAFQTFLDELHETGQLHSMSTWMELYPAVSTDVRFANMLGQPGSTP 540
RARLRERRQQRKNREAFQTFLDELHETGQLHSMSTWMELYPAVSTDVRFANMLGQPGSTP
Sbjct: 481 RARLRERRQQRKNREAFQTFLDELHETGQLHSMSTWMELYPAVSTDVRFANMLGQPGSTP 540
Query: 541 LDLFKFYVEELKARFHDEKKIIKDILKDRGFCVEVNTAFEDFAHVISFDKRAAALDAGNI 600
LDLFKFYVEELKARFHDEKKIIKDILKDRGFCVEVNTAFEDFAHVISFDKRAAALDAGNI
Sbjct: 541 LDLFKFYVEELKARFHDEKKIIKDILKDRGFCVEVNTAFEDFAHVISFDKRAAALDAGNI 600
Query: 601 KLTFNSLLEKAEAREREREKEEARRMRRREAAFRSMLRQAVPALELGTAWEEVRERFVCD 660
KLTFNSLLEKAEAREREREKEEARRMRRREAAFRSMLRQAVPALELGTAWEEVRERFVCD
Sbjct: 601 KLTFNSLLEKAEAREREREKEEARRMRRREAAFRSMLRQAVPALELGTAWEEVRERFVCD 660
Query: 661 SAFEQITLESERIRLFREFLQVLEQTECQHLHTKGRKHGRKGKKHHHKRSHSPSGSESEE 720
SAFEQITLESERIRLFREFLQVLEQTECQHLHTKGRKHGRKGKKHHHKRSHSPSGSESEE
Sbjct: 661 SAFEQITLESERIRLFREFLQVLEQTECQHLHTKGRKHGRKGKKHHHKRSHSPSGSESEE 720
Query: 721 EELPPPSLRPPKRRRRNPSESGSEPSSSLDSVESGGAALGGRGSPSSHLLGADHGLRKAK 780
EELPPPSLRPPKRRRRNPSESGSEPSSSLDSVESGGAALGGRGSPSSHLLGADHGLRKAK
Sbjct: 721 EELPPPSLRPPKRRRRNPSESGSEPSSSLDSVESGGAALGGRGSPSSHLLGADHGLRKAK 780
Query: 781 KPKKKTKKRRHKSNSPESETDPEEKAGKESDEKEQEQDKDRELQQAELPNRSPGFGIKKE 840
KPKKKTKKRRHKSNSPESETDPEEKAGKESDEKEQEQDKDRELQQAELPNRSPGFGIKKE
Sbjct: 781 KPKKKTKKRRHKSNSPESETDPEEKAGKESDEKEQEQDKDRELQQAELPNRSPGFGIKKE 840
Query: 841 KTGWDTSESELSEGELERRRRTLLQQLDDHQ 871
KTGWDTSESELSEGELERRRRTLLQQLDDHQ
Sbjct: 841 KTGWDTSESELSEGELERRRRTLLQQLDDHQ 871
>gi|29789008 Huntingtin interacting protein C isoform 2 [Homo
sapiens]
Length = 858
Score = 1733 bits (4489), Expect = 0.0
Identities = 858/865 (99%), Positives = 858/865 (99%), Gaps = 7/865 (0%)
Query: 7 MPPPGIPPPFPPMGLPPMSQRPPAIPPMPPGILPPMLPPMGAPPPLTQIPGMVPPMMPGM 66
MPPPGIPPPFPPMGLPPMSQRPPAIPPMPPGILPPMLPPMGAPPPLTQIPGMVPPMMPGM
Sbjct: 1 MPPPGIPPPFPPMGLPPMSQRPPAIPPMPPGILPPMLPPMGAPPPLTQIPGMVPPMMPGM 60
Query: 67 LMPAVPVTAATAPGADTASSAVAGTGPPRALWSEHVAPDGRIYYYNADDKQSVWEKPSVL 126
LMPAVPVTAATAPGADTASSAVAGTGPPRALWSEHVAPDGRIYYYNADDKQSVWEKPSVL
Sbjct: 61 LMPAVPVTAATAPGADTASSAVAGTGPPRALWSEHVAPDGRIYYYNADDKQSVWEKPSVL 120
Query: 127 KSKAELLLSQCPWKEYKSDTGKPYYYNNQSKESRWTRPKDLDDLEVLVKQEAAGKQQQQL 186
KSKAELLLSQCPWKEYKSDTGKPYYYNNQSKESRWTRPKDLDDLEVLVKQEAAGKQQQQL
Sbjct: 121 KSKAELLLSQCPWKEYKSDTGKPYYYNNQSKESRWTRPKDLDDLEVLVKQEAAGKQQQQL 180
Query: 187 PQTLQPQPPQPQPDPPPVPPGPTPVPTGLLEPEPGGSEDCDVLEATQPLEQGFLQQLEEG 246
PQTLQPQPPQPQPDPPPVPPGPTPVPTGLLEPEPGGSEDCDVLEATQPLEQGFLQQLEEG
Sbjct: 181 PQTLQPQPPQPQPDPPPVPPGPTPVPTGLLEPEPGGSEDCDVLEATQPLEQGFLQQLEEG 240
Query: 247 PSSSGQHQPQQEEEESKPEPERSGLSWSNREKAKQAFKELLRDKAVPSNASWEQAMKMVV 306
PSSSGQHQPQQEEEESKPEPERSGLSWSNREKAKQAFKELLRDKAVPSNASWEQAMKMVV
Sbjct: 241 PSSSGQHQPQQEEEESKPEPERSGLSWSNREKAKQAFKELLRDKAVPSNASWEQAMKMVV 300
Query: 307 TDPRYSALPKLSEKKQAFNAYKAQREKEEKEEARLRAKEAKQTLQHFLEQHERMTSTTRY 366
TDPRYSALPKLSEKKQAFNAYKAQREKEEKEEARLRAKEAKQTLQHFLEQHERMTSTTRY
Sbjct: 301 TDPRYSALPKLSEKKQAFNAYKAQREKEEKEEARLRAKEAKQTLQHFLEQHERMTSTTRY 360
Query: 367 RRAEQTFGELEVWAVVPERDRKEVYDDVLFFLAKKEKEQAKQLRRRNIQALKSILDGMSS 426
RRAEQTFGELEVWAVVPERDRKEVYDDVLFFLAKKEKEQAKQLRRRNIQALKSILDGMSS
Sbjct: 361 RRAEQTFGELEVWAVVPERDRKEVYDDVLFFLAKKEKEQAKQLRRRNIQALKSILDGMSS 420
Query: 427 VNFQTTWSQAQQYLMDNPSFAQDHQLQNMDKEDALICFEEHIRALEREEEEERERARLRE 486
VNFQTTWSQAQQYLMDNPSFAQDHQLQNMDKEDALICFEEHIRALEREEEEERERARLRE
Sbjct: 421 VNFQTTWSQAQQYLMDNPSFAQDHQLQNMDKEDALICFEEHIRALEREEEEERERARLRE 480
Query: 487 RRQQRKNREAFQTFLDELHETGQLHSMSTWMELYPAVSTDVRFANMLGQPGSTPLDLFKF 546
RRQQRKNREAFQTFLDELHETGQLHSMSTWMELYPAVSTDVRFANMLGQPGSTPLDLFKF
Sbjct: 481 RRQQRKNREAFQTFLDELHETGQLHSMSTWMELYPAVSTDVRFANMLGQPGSTPLDLFKF 540
Query: 547 YVEELKARFHDEKKIIKDILKDRGFCVEVNTAFEDFAHVISFDKRAAALDAGNIKLTFNS 606
YVEELKARFHDEKKIIKDILK VNTAFEDFAHVISFDKRAAALDAGNIKLTFNS
Sbjct: 541 YVEELKARFHDEKKIIKDILK-------VNTAFEDFAHVISFDKRAAALDAGNIKLTFNS 593
Query: 607 LLEKAEAREREREKEEARRMRRREAAFRSMLRQAVPALELGTAWEEVRERFVCDSAFEQI 666
LLEKAEAREREREKEEARRMRRREAAFRSMLRQAVPALELGTAWEEVRERFVCDSAFEQI
Sbjct: 594 LLEKAEAREREREKEEARRMRRREAAFRSMLRQAVPALELGTAWEEVRERFVCDSAFEQI 653
Query: 667 TLESERIRLFREFLQVLEQTECQHLHTKGRKHGRKGKKHHHKRSHSPSGSESEEEELPPP 726
TLESERIRLFREFLQVLEQTECQHLHTKGRKHGRKGKKHHHKRSHSPSGSESEEEELPPP
Sbjct: 654 TLESERIRLFREFLQVLEQTECQHLHTKGRKHGRKGKKHHHKRSHSPSGSESEEEELPPP 713
Query: 727 SLRPPKRRRRNPSESGSEPSSSLDSVESGGAALGGRGSPSSHLLGADHGLRKAKKPKKKT 786
SLRPPKRRRRNPSESGSEPSSSLDSVESGGAALGGRGSPSSHLLGADHGLRKAKKPKKKT
Sbjct: 714 SLRPPKRRRRNPSESGSEPSSSLDSVESGGAALGGRGSPSSHLLGADHGLRKAKKPKKKT 773
Query: 787 KKRRHKSNSPESETDPEEKAGKESDEKEQEQDKDRELQQAELPNRSPGFGIKKEKTGWDT 846
KKRRHKSNSPESETDPEEKAGKESDEKEQEQDKDRELQQAELPNRSPGFGIKKEKTGWDT
Sbjct: 774 KKRRHKSNSPESETDPEEKAGKESDEKEQEQDKDRELQQAELPNRSPGFGIKKEKTGWDT 833
Query: 847 SESELSEGELERRRRTLLQQLDDHQ 871
SESELSEGELERRRRTLLQQLDDHQ
Sbjct: 834 SESELSEGELERRRRTLLQQLDDHQ 858
>gi|151301228 formin binding protein 3 [Homo sapiens]
Length = 930
Score = 961 bits (2483), Expect = 0.0
Identities = 501/928 (53%), Positives = 638/928 (68%), Gaps = 105/928 (11%)
Query: 16 FPPMGLPPMSQRPPAIPPMPPGILPPMLPPMGAPPPLTQIPGMVPPMMPGMLMPAVPVTA 75
+ PMG+ PM QR +PP+P G++P M+PPMG PP + Q+PGM+ +MPGM+M + +
Sbjct: 36 YAPMGMHPMGQRAN-MPPVPHGMMPQMMPPMGGPP-MGQMPGMMSSVMPGMMMSHMSQAS 93
Query: 76 ---ATAPGADTASSAVAGTGPPRALWSEHVAPDGRIYYYNADDKQSVWEKPSVLKSKAEL 132
A PG ++ A +++W+EH +PDGR YYYN + KQS WEKP LK+ AE
Sbjct: 94 MQPALPPGVNSMDVAAGTASGAKSMWTEHKSPDGRTYYYNTETKQSTWEKPDDLKTPAEQ 153
Query: 133 LLSQCPWKEYKSDTGKPYYYNNQSKESRWTRPKDLDDLE------------------VLV 174
LLS+CPWKEYKSD+GKPYYYN+Q+KESRW +PK+L+DLE ++
Sbjct: 154 LLSKCPWKEYKSDSGKPYYYNSQTKESRWAKPKELEDLEGYQNTIVAGSLITKSNLHAMI 213
Query: 175 KQEAAGKQQQQLPQTLQPQPPQPQPDPPP------------------------------- 203
K E + KQ++ + P P P
Sbjct: 214 KAEESSKQEECTTTSTAPVPTTEIPTTMSTMAAAEAAAAVVAAAAAAAAAAAAANANAST 273
Query: 204 ---------VPPGPTPVPTGLLEPEPGGSEDCDVL---EATQPLEQGFLQQLEEGPSSSG 251
VP P P T ++ + +A Q E S++G
Sbjct: 274 SASNTVSGTVPVVPEPEVTSIVATVVDNENTVTISTEEQAQLTSTPAIQDQSVEVSSNTG 333
Query: 252 QHQPQQE--------EEESKPEPERSGLSWSNREKAKQAFKELLRDKAVPSNASWEQAMK 303
+ +QE +EE + +P + +W+ +E+AKQAFKELL++K VPSNASWEQAMK
Sbjct: 334 EETSKQETVADFTPKKEEEESQPAKKTYTWNTKEEAKQAFKELLKEKRVPSNASWEQAMK 393
Query: 304 MVVTDPRYSALPKLSEKKQAFNAYKAQREKEEKEEARLRAKEAKQTLQHFLEQHERMTST 363
M++ DPRYSAL KLSEKKQAFNAYK Q EKEEKEEAR + KEAK++ Q FLE HE+MTST
Sbjct: 394 MIINDPRYSALAKLSEKKQAFNAYKVQTEKEEKEEARSKYKEAKESFQRFLENHEKMTST 453
Query: 364 TRYRRAEQTFGELEVWAVVPERDRKEVYDDVLFFLAKKEKEQAKQLRRRNIQALKSILDG 423
TRY++AEQ FGE+EVW + ERDR E+Y+DVLFFL+KKEKEQAKQLR+RN +ALK+ILD
Sbjct: 454 TRYKKAEQMFGEMEVWNAISERDRLEIYEDVLFFLSKKEKEQAKQLRKRNWEALKNILDN 513
Query: 424 MSSVNFQTTWSQAQQYLMDNPSFAQDHQLQNMDKEDALICFEEHIRALEREEEEERERAR 483
M++V + TTWS+AQQYLMDNP+FA+D +LQNMDKEDALICFEEHIRALE+EEEEE++++
Sbjct: 514 MANVTYSTTWSEAQQYLMDNPTFAEDEELQNMDKEDALICFEEHIRALEKEEEEEKQKSL 573
Query: 484 LRERRQQRKNREAFQTFLDELHETGQLHSMSTWMELYPAVSTDVRFANMLGQPGSTPLDL 543
LRERR+QRKNRE+FQ FLDELHE GQLHSMS+WMELYP +S+D+RF NMLGQPGST LDL
Sbjct: 574 LRERRRQRKNRESFQIFLDELHEHGQLHSMSSWMELYPTISSDIRFTNMLGQPGSTALDL 633
Query: 544 FKFYVEELKARFHDEKKIIKDILKDRGFCVEVNTAFEDFAHVISFDKRAAALDAGNIKLT 603
FKFYVE+LKAR+HDEKKIIKDILKD+GF VEVNT FEDF +IS KR+ LDAGNIKL
Sbjct: 634 FKFYVEDLKARYHDEKKIIKDILKDKGFVVEVNTTFEDFVAIISSTKRSTTLDAGNIKLA 693
Query: 604 FNSLLEKAEAREREREKEEARRMRRREAAFRSMLRQAVPALELGTAWEEVRERFVCDSAF 663
FNSLLEKAEAREREREKEEAR+M+R+E+AF+SML+QA P +EL WE++RERFV + AF
Sbjct: 694 FNSLLEKAEAREREREKEEARKMKRKESAFKSMLKQAAPPIELDAVWEDIRERFVKEPAF 753
Query: 664 EQITLESERIRLFREFLQVLEQTECQHLHTKGRKHGRKGKKHHHKRSHSPSGSESEEEEL 723
E ITLESER R+F++F+ VLE ECQH H+K +KH +K KKHH KRS S SGS+S++++
Sbjct: 754 EDITLESERKRIFKDFMHVLEH-ECQHHHSKNKKHSKKSKKHHRKRSRSRSGSDSDDDD- 811
Query: 724 PPPSLRPPKRRRRNPSESGSEPSSSLDSVESGGAALGGRGSPSSHLLGADHGLRKAKKPK 783
K+R+R+ S S SE SSS +S + +K+KK K
Sbjct: 812 ----SHSKKKRQRSESRSASEHSSSAES---------------------ERSYKKSKKHK 846
Query: 784 KKTKKRRHKSNSPESETDPEEKAGKESDEKEQEQDKDRELQQAELPNRSPGFGIKKEKTG 843
KK+KKRRHKS+SPES+ + E K+ EK++E +KDR Q++E ++SP K+
Sbjct: 847 KKSKKRRHKSDSPESDAERE----KDKKEKDRESEKDRTRQRSESKHKSPKKKTGKDSGN 902
Query: 844 WDTSESELSEGELERRRRTLLQQLDDHQ 871
WDTS SELSEGELE+RRRTLL+QLDD Q
Sbjct: 903 WDTSGSELSEGELEKRRRTLLEQLDDDQ 930
>gi|91208418 transcription elongation regulator 1 isoform 2 [Homo
sapiens]
Length = 1077
Score = 140 bits (353), Expect = 5e-33
Identities = 179/723 (24%), Positives = 293/723 (40%), Gaps = 126/723 (17%)
Query: 3 PPPFMPPPGIPPPFPPMGLPP-----MSQRPPAIPPMPPGILPPMLPPM-GAPPPLTQI- 55
P P P P P LPP + Q AIP PP ++PP P+ G P PL +
Sbjct: 322 PAPTATPVQTVPQPHPQTLPPAVPHSVPQPTTAIPAFPPVMVPPFRVPLPGMPIPLPGVL 381
Query: 56 PGMVPPMMPGMLMPAVPVTA--ATAPGADTASSAVAGTGPPRALWSEHVAPDGRIYYYNA 113
PGM PP++P M+ P V + A AT GA S W+E+ DG+ YYYN
Sbjct: 382 PGMAPPIVP-MIHPQVAIAASPATLAGATAVSE-----------WTEYKTADGKTYYYNN 429
Query: 114 DDKQSVWEKPSVLKSKAELLLS-QCPWKEYKSDTGKPYYYNNQSKESRWTRPKDLDDLEV 172
+S WEKP LK K +L + P KE + KE K+ E
Sbjct: 430 RTLESTWEKPQELKEKEKLEEKIKEPIKEPSEEPLPMETEEEDPKEEPIKEIKEEPKEEE 489
Query: 173 LVKQEAAGKQQQQLPQTLQPQPPQP---------------------QPDPPPVPPGPTPV 211
+ ++E A Q+ P P P P D P G V
Sbjct: 490 MTEEEKAA--QKAKPVATAPIPGTPWCVVWTGDERVFFYNPTTRLSMWDRPDDLIGRADV 547
Query: 212 PTGLLE-PEPGGSEDCDVLEATQPL----------------EQGFLQQLEEGPSSSGQHQ 254
+ E P G E+ L P EQ ++++ E + +
Sbjct: 548 DKIIQEPPHKKGMEELKKLRHPTPTMLSIQKWQFSMSAIKEEQELMEEINEDEPVKAKKR 607
Query: 255 PQQEEE--ESKPEPERSGLSWSNREKA-------KQAFKELLRDKAVPSNASWEQAMKMV 305
+ + + +S+ E + RE+A + FK++L ++ V + ++WE+ + +
Sbjct: 608 KRDDNKDIDSEKEAAMEAEIKAARERAIVPLEARMKQFKDMLLERGVSAFSTWEKELHKI 667
Query: 306 VTDPRYSAL-PKLSEKKQAFNAYKAQREKEEKEEARLRAKEAKQTLQHFLEQHERMTSTT 364
V DPRY L PK E+KQ F+ Y R +EE+ E + + +AK+ + +E+ + T
Sbjct: 668 VFDPRYLLLNPK--ERKQVFDQYVKTRAEEERREKKNKIMQAKEDFKKMMEEAKFNPRAT 725
Query: 365 RYRRAEQTFGELEVWAVVPERDRKEVYDDVLFFLAKKEKEQAKQLRRRNIQALKSILDGM 424
A + + A+ +DR+ ++++ + KKEKE +K R I++ L
Sbjct: 726 FSEFAAKHAKDSRFKAIEKMKDREALFNEFVAAARKKEKEDSK-TRGEKIKSDFFELLSN 784
Query: 425 SSVNFQTTWSQAQQYLMDNPSF-AQDHQLQNMDKEDALICFEEHIRALEREEEEERER-- 481
++ Q+ WS+ + + +P + A D D I E+ + L+ E+E+E ER
Sbjct: 785 HHLDSQSRWSKVKDKVESDPRYKAVDSSSMREDLFKQYI--EKIAKNLDSEKEKELERQA 842
Query: 482 ---ARLRER------------------RQQRKNREAFQTFLDELHETGQLHSMSTWMELY 520
A LRER R+Q K EA Q F L + + +S W +
Sbjct: 843 RIEASLREREREVQKARSEQTKEIDREREQHKREEAIQNFKALLSDMVRSSDVS-WSDTR 901
Query: 521 PAVSTDVRFANMLGQPGSTPLDLFKFYVEEL--KARFHDEKKIIKDILKDRGFCVEVNTA 578
+ D R+ + LF ++E L K R H + L D + + +
Sbjct: 902 RTLRKDHRWESGSLLEREEKEKLFNEHIEALTKKKREHFRQ------LLDETSAITLTST 955
Query: 579 FEDFAHVISFDKRAAALDAGNIKLTFNSLLEKAEAREREREKEEARRMR--RREAAFRSM 636
+++ +I D R + + R+++RE EE R + +A FR++
Sbjct: 956 WKEVKKIIKEDPRCIKFSSSD--------------RKKQREFEEYIRDKYITAKADFRTL 1001
Query: 637 LRQ 639
L++
Sbjct: 1002 LKE 1004
Score = 92.0 bits (227), Expect = 2e-18
Identities = 57/138 (41%), Positives = 68/138 (49%), Gaps = 27/138 (19%)
Query: 3 PPPFMPPPGIPPPFPPMGLPPMSQRPP-AIPPMPPGILPPMLPPMGAPPPL----TQIPG 57
PPP M PP PPF M PP RPP PP P +PPM PP G PPP+ Q P
Sbjct: 43 PPPLMRPP---PPFGMMRGPPPPPRPPFGRPPFDPN-MPPMPPPGGIPPPMGPPHLQRPP 98
Query: 58 MVPPMM------PGMLMP--AVPVTAATAPGADTASSAVAGTGPPRALWSEHVAPDGRIY 109
+PP M PGM+ P PVTA P P +W E+ PDG++Y
Sbjct: 99 FMPPPMSSMPPPPGMMFPPGMPPVTAPGTPALP----------PTEEIWVENKTPDGKVY 148
Query: 110 YYNADDKQSVWEKPSVLK 127
YYNA ++S W KP +K
Sbjct: 149 YYNARTRESAWTKPDGVK 166
Score = 74.3 bits (181), Expect = 4e-13
Identities = 108/577 (18%), Positives = 218/577 (37%), Gaps = 107/577 (18%)
Query: 88 VAGTGPPRALWSEHVAPDGRIYYYNADDKQSVWEKPSVLKSKAEL--LLSQCPWKEYKSD 145
VA P W D R+++YN + S+W++P L +A++ ++ + P K+ +
Sbjct: 503 VATAPIPGTPWCVVWTGDERVFFYNPTTRLSMWDRPDDLIGRADVDKIIQEPPHKKGMEE 562
Query: 146 TGKPYYYNNQSKESRWTRPKDLDDLEVLVKQEAAGKQQQQLPQTLQPQPPQPQPDPPPVP 205
K+ R P L + A ++Q+ + + + +P + +
Sbjct: 563 L----------KKLRHPTPTMLSIQKWQFSMSAIKEEQELMEEINEDEPVKAKKRKRDDN 612
Query: 206 PGPTPVPTGLLEPEPGGSEDCDVLEATQPLEQGFLQQLEEGPSSSGQHQPQ--------- 256
+E E + + ++ ++Q LE G S+ + +
Sbjct: 613 KDIDSEKEAAMEAEIKAARERAIVPLEARMKQFKDMLLERGVSAFSTWEKELHKIVFDPR 672
Query: 257 ------QEEEESKPEPERSGLSWSNREK------AKQAFKELLRDKAVPSNASWEQAMKM 304
+E ++ + ++ REK AK+ FK+++ + A++ +
Sbjct: 673 YLLLNPKERKQVFDQYVKTRAEEERREKKNKIMQAKEDFKKMMEEAKFNPRATFSEFAAK 732
Query: 305 VVTDPRYSALPKLSEKKQAFNAYKAQREKEEKEEARLRAKEAKQTLQHFLEQH------- 357
D R+ A+ K+ +++ FN + A K+EKE+++ R ++ K L H
Sbjct: 733 HAKDSRFKAIEKMKDREALFNEFVAAARKKEKEDSKTRGEKIKSDFFELLSNHHLDSQSR 792
Query: 358 -----ERMTSTTRYRRAEQTFGELEVWAVVPERDRKEVYDD----------VLFFLAKKE 402
+++ S RY+ + + +++ E+ K + + + L ++E
Sbjct: 793 WSKVKDKVESDPRYKAVDSSSMREDLFKQYIEKIAKNLDSEKEKELERQARIEASLRERE 852
Query: 403 K-------EQAKQL--------RRRNIQALKSILDGMSSVNFQTTWSQAQQYLMDNPSFA 447
+ EQ K++ R IQ K++L M + +WS ++ L + +
Sbjct: 853 REVQKARSEQTKEIDREREQHKREEAIQNFKALLSDMVR-SSDVSWSDTRRTLRKDHRWE 911
Query: 448 QDHQLQNMDKEDALICFEEHIRALEREEEEERERARLRERRQQRKNREAFQTFLDELHET 507
L+ +KE F EHI AL +K RE F+ LD ET
Sbjct: 912 SGSLLEREEKEK---LFNEHIEAL------------------TKKKREHFRQLLD---ET 947
Query: 508 GQLHSMSTWMELYPAVSTDVRFANMLGQPGSTPLDLFKFYVEELKARFHDEKKIIKDILK 567
+ STW E+ + D R S+ + + E ++ ++ K + +LK
Sbjct: 948 SAITLTSTWKEVKKIIKEDPRCIKF----SSSDRKKQREFEEYIRDKYITAKADFRTLLK 1003
Query: 568 DRGFCV--------EVNTAFEDFAHVISFDKRAAALD 596
+ F E + +D ++ DKR LD
Sbjct: 1004 ETKFITYRSKKLIQESDQHLKDVEKILQNDKRYLVLD 1040
Score = 55.1 bits (131), Expect = 3e-07
Identities = 112/538 (20%), Positives = 207/538 (38%), Gaps = 87/538 (16%)
Query: 184 QQLPQTLQPQPPQPQPDP-------PPV--PPGPTPVPTGLLEPEPGGSEDCDVLEATQP 234
Q PQTL P P P P PPV PP P+P G+ P PG VL P
Sbjct: 334 QPHPQTLPPAVPHSVPQPTTAIPAFPPVMVPPFRVPLP-GMPIPLPG------VLPGMAP 386
Query: 235 LEQGFLQQ---LEEGPSSSGQHQPQQEEEESKPEPERSGLSWSNREKAKQAFKELLRDKA 291
+ + P++ E E K G ++ + ++ E + +
Sbjct: 387 PIVPMIHPQVAIAASPATLAGATAVSEWTEYKTA---DGKTYYYNNRTLESTWE--KPQE 441
Query: 292 VPSNASWEQAMKMVVTDPRYSALPKLSE----KKQAFNAYKAQREKEEKEEARLRAKEAK 347
+ E+ +K + +P LP +E K++ K + ++EE E A++AK
Sbjct: 442 LKEKEKLEEKIKEPIKEPSEEPLPMETEEEDPKEEPIKEIKEEPKEEEMTEEEKAAQKAK 501
Query: 348 Q---------------TLQHFLEQHERMTSTTRYRRAEQTFGELEVWAVVPERDRKEVYD 392
T + + T + + R + G +V ++ E K
Sbjct: 502 PVATAPIPGTPWCVVWTGDERVFFYNPTTRLSMWDRPDDLIGRADVDKIIQEPPHK---- 557
Query: 393 DVLFFLAKKEKEQAKQLRRRNIQALKSILDGMSSVNFQTTWSQAQQYLMDNPSFAQDHQL 452
K E+ K+LR L + F + + +Q LM+ + + +
Sbjct: 558 --------KGMEELKKLRHPTPTMLS-----IQKWQFSMSAIKEEQELMEEINEDEPVKA 604
Query: 453 QNMDKEDALICFEEHIRALEREEEEERERARLRERRQQRKNREAFQTFLDELHETGQLHS 512
+ ++D E A+E E + RERA + + ++ F D L E G + +
Sbjct: 605 KKRKRDDNKDIDSEKEAAMEAEIKAARERAIVPLEARMKQ-------FKDMLLERG-VSA 656
Query: 513 MSTWMELYPAVSTDVRFANMLGQPGSTPLDLFKFYVE--------ELKARFHDEKKIIKD 564
STW + + D R+ +L P +F YV+ E K + K+ K
Sbjct: 657 FSTWEKELHKIVFDPRY--LLLNPKERK-QVFDQYVKTRAEEERREKKNKIMQAKEDFKK 713
Query: 565 ILKDRGFCVEVNTAFEDFAHVISFDKRAAALDA-GNIKLTFNSLLEKAEAREREREKEEA 623
++++ F F +FA + D R A++ + + FN + A AR++E+E +
Sbjct: 714 MMEEAKF--NPRATFSEFAAKHAKDSRFKAIEKMKDREALFNEFV--AAARKKEKEDSKT 769
Query: 624 RRMRRREAAFRSMLRQAVPALELGTAWEEVRERFVCDSAFEQITLESERIRLFREFLQ 681
R + + F + L+ + W +V+++ D ++ + S R LF+++++
Sbjct: 770 RGEKIKSDFFELLSNHH---LDSQSRWSKVKDKVESDPRYKAVDSSSMREDLFKQYIE 824
Score = 47.4 bits (111), Expect = 6e-05
Identities = 39/138 (28%), Positives = 62/138 (44%), Gaps = 7/138 (5%)
Query: 560 KIIKDILKDRGFCVEVNTAFEDFAHVISFDKRAAALDAGNIKLTFNSLLEKAEARERERE 619
K KD+L +RG V + +E H I FD R L+ K F+ + K A E RE
Sbjct: 643 KQFKDMLLERG--VSAFSTWEKELHKIVFDPRYLLLNPKERKQVFDQYV-KTRAEEERRE 699
Query: 620 KEEARRMRRREAAFRSMLRQAVPALELGTAWEEVRERFVCDSAFEQITLESERIRLFREF 679
K+ ++ + + F+ M+ +A + E + DS F+ I +R LF EF
Sbjct: 700 KKN--KIMQAKEDFKKMMEEA--KFNPRATFSEFAAKHAKDSRFKAIEKMKDREALFNEF 755
Query: 680 LQVLEQTECQHLHTKGRK 697
+ + E + T+G K
Sbjct: 756 VAAARKKEKEDSKTRGEK 773
>gi|21327715 transcription elongation regulator 1 isoform 1 [Homo
sapiens]
Length = 1098
Score = 132 bits (333), Expect = 1e-30
Identities = 176/733 (24%), Positives = 293/733 (39%), Gaps = 138/733 (18%)
Query: 3 PPPFMPPPGIP----------PPFPPMGLPPMSQRPPAIPPMPPGILPPMLPPMGAPPPL 52
P P PP +P P FPP+ +PP P +P PG+ M+ + P
Sbjct: 335 PHPQTLPPAVPHSVPQPTTAIPAFPPVMVPPFRVPLPGMPIPLPGV--AMMQIVSCPYVK 392
Query: 53 T-------QIPGMVPPMMPGMLMPAVPVTA--ATAPGADTASSAVAGTGPPRALWSEHVA 103
T +PGM PP++P M+ P V + A AT GA S W+E+
Sbjct: 393 TVATTKTGVLPGMAPPIVP-MIHPQVAIAASPATLAGATAVSE-----------WTEYKT 440
Query: 104 PDGRIYYYNADDKQSVWEKPSVLKSKAELLLS-QCPWKEYKSDTGKPYYYNNQSKESRWT 162
DG+ YYYN +S WEKP LK K +L + P KE + KE
Sbjct: 441 ADGKTYYYNNRTLESTWEKPQELKEKEKLEEKIKEPIKEPSEEPLPMETEEEDPKEEPIK 500
Query: 163 RPKDLDDLEVLVKQEAAGKQQQQLPQTLQPQPPQP---------------------QPDP 201
K+ E + ++E A Q+ P P P P D
Sbjct: 501 EIKEEPKEEEMTEEEKAA--QKAKPVATAPIPGTPWCVVWTGDERVFFYNPTTRLSMWDR 558
Query: 202 PPVPPGPTPVPTGLLE-PEPGGSEDCDVLEATQPL----------------EQGFLQQLE 244
P G V + E P G E+ L P EQ ++++
Sbjct: 559 PDDLIGRADVDKIIQEPPHKKGMEELKKLRHPTPTMLSIQKWQFSMSAIKEEQELMEEIN 618
Query: 245 EGPSSSGQHQPQQEEE--ESKPEPERSGLSWSNREKA-------KQAFKELLRDKAVPSN 295
E + + + + + +S+ E + RE+A + FK++L ++ V +
Sbjct: 619 EDEPVKAKKRKRDDNKDIDSEKEAAMEAEIKAARERAIVPLEARMKQFKDMLLERGVSAF 678
Query: 296 ASWEQAMKMVVTDPRYSAL-PKLSEKKQAFNAYKAQREKEEKEEARLRAKEAKQTLQHFL 354
++WE+ + +V DPRY L PK E+KQ F+ Y R +EE+ E + + +AK+ + +
Sbjct: 679 STWEKELHKIVFDPRYLLLNPK--ERKQVFDQYVKTRAEEERREKKNKIMQAKEDFKKMM 736
Query: 355 EQHERMTSTTRYRRAEQTFGELEVWAVVPERDRKEVYDDVLFFLAKKEKEQAKQLRRRNI 414
E+ + T A + + A+ +DR+ ++++ + KKEKE +K R I
Sbjct: 737 EEAKFNPRATFSEFAAKHAKDSRFKAIEKMKDREALFNEFVAAARKKEKEDSK-TRGEKI 795
Query: 415 QALKSILDGMSSVNFQTTWSQAQQYLMDNPSF-AQDHQLQNMDKEDALICFEEHIRALER 473
++ L ++ Q+ WS+ + + +P + A D D I E+ + L+
Sbjct: 796 KSDFFELLSNHHLDSQSRWSKVKDKVESDPRYKAVDSSSMREDLFKQYI--EKIAKNLDS 853
Query: 474 EEEEERER-----ARLRER------------------RQQRKNREAFQTFLDELHETGQL 510
E+E+E ER A LRER R+Q K EA Q F L + +
Sbjct: 854 EKEKELERQARIEASLREREREVQKARSEQTKEIDREREQHKREEAIQNFKALLSDMVRS 913
Query: 511 HSMSTWMELYPAVSTDVRFANMLGQPGSTPLDLFKFYVEEL--KARFHDEKKIIKDILKD 568
+S W + + D R+ + LF ++E L K R H + L D
Sbjct: 914 SDVS-WSDTRRTLRKDHRWESGSLLEREEKEKLFNEHIEALTKKKREHFRQ------LLD 966
Query: 569 RGFCVEVNTAFEDFAHVISFDKRAAALDAGNIKLTFNSLLEKAEAREREREKEEARRMR- 627
+ + + +++ +I D R + + R+++RE EE R +
Sbjct: 967 ETSAITLTSTWKEVKKIIKEDPRCIKFSSSD--------------RKKQREFEEYIRDKY 1012
Query: 628 -RREAAFRSMLRQ 639
+A FR++L++
Sbjct: 1013 ITAKADFRTLLKE 1025
Score = 92.0 bits (227), Expect = 2e-18
Identities = 57/138 (41%), Positives = 68/138 (49%), Gaps = 27/138 (19%)
Query: 3 PPPFMPPPGIPPPFPPMGLPPMSQRPP-AIPPMPPGILPPMLPPMGAPPPL----TQIPG 57
PPP M PP PPF M PP RPP PP P +PPM PP G PPP+ Q P
Sbjct: 43 PPPLMRPP---PPFGMMRGPPPPPRPPFGRPPFDPN-MPPMPPPGGIPPPMGPPHLQRPP 98
Query: 58 MVPPMM------PGMLMP--AVPVTAATAPGADTASSAVAGTGPPRALWSEHVAPDGRIY 109
+PP M PGM+ P PVTA P P +W E+ PDG++Y
Sbjct: 99 FMPPPMSSMPPPPGMMFPPGMPPVTAPGTPALP----------PTEEIWVENKTPDGKVY 148
Query: 110 YYNADDKQSVWEKPSVLK 127
YYNA ++S W KP +K
Sbjct: 149 YYNARTRESAWTKPDGVK 166
Score = 74.3 bits (181), Expect = 4e-13
Identities = 108/577 (18%), Positives = 218/577 (37%), Gaps = 107/577 (18%)
Query: 88 VAGTGPPRALWSEHVAPDGRIYYYNADDKQSVWEKPSVLKSKAEL--LLSQCPWKEYKSD 145
VA P W D R+++YN + S+W++P L +A++ ++ + P K+ +
Sbjct: 524 VATAPIPGTPWCVVWTGDERVFFYNPTTRLSMWDRPDDLIGRADVDKIIQEPPHKKGMEE 583
Query: 146 TGKPYYYNNQSKESRWTRPKDLDDLEVLVKQEAAGKQQQQLPQTLQPQPPQPQPDPPPVP 205
K+ R P L + A ++Q+ + + + +P + +
Sbjct: 584 L----------KKLRHPTPTMLSIQKWQFSMSAIKEEQELMEEINEDEPVKAKKRKRDDN 633
Query: 206 PGPTPVPTGLLEPEPGGSEDCDVLEATQPLEQGFLQQLEEGPSSSGQHQPQ--------- 256
+E E + + ++ ++Q LE G S+ + +
Sbjct: 634 KDIDSEKEAAMEAEIKAARERAIVPLEARMKQFKDMLLERGVSAFSTWEKELHKIVFDPR 693
Query: 257 ------QEEEESKPEPERSGLSWSNREK------AKQAFKELLRDKAVPSNASWEQAMKM 304
+E ++ + ++ REK AK+ FK+++ + A++ +
Sbjct: 694 YLLLNPKERKQVFDQYVKTRAEEERREKKNKIMQAKEDFKKMMEEAKFNPRATFSEFAAK 753
Query: 305 VVTDPRYSALPKLSEKKQAFNAYKAQREKEEKEEARLRAKEAKQTLQHFLEQH------- 357
D R+ A+ K+ +++ FN + A K+EKE+++ R ++ K L H
Sbjct: 754 HAKDSRFKAIEKMKDREALFNEFVAAARKKEKEDSKTRGEKIKSDFFELLSNHHLDSQSR 813
Query: 358 -----ERMTSTTRYRRAEQTFGELEVWAVVPERDRKEVYDD----------VLFFLAKKE 402
+++ S RY+ + + +++ E+ K + + + L ++E
Sbjct: 814 WSKVKDKVESDPRYKAVDSSSMREDLFKQYIEKIAKNLDSEKEKELERQARIEASLRERE 873
Query: 403 K-------EQAKQL--------RRRNIQALKSILDGMSSVNFQTTWSQAQQYLMDNPSFA 447
+ EQ K++ R IQ K++L M + +WS ++ L + +
Sbjct: 874 REVQKARSEQTKEIDREREQHKREEAIQNFKALLSDMVR-SSDVSWSDTRRTLRKDHRWE 932
Query: 448 QDHQLQNMDKEDALICFEEHIRALEREEEEERERARLRERRQQRKNREAFQTFLDELHET 507
L+ +KE F EHI AL +K RE F+ LD ET
Sbjct: 933 SGSLLEREEKEK---LFNEHIEAL------------------TKKKREHFRQLLD---ET 968
Query: 508 GQLHSMSTWMELYPAVSTDVRFANMLGQPGSTPLDLFKFYVEELKARFHDEKKIIKDILK 567
+ STW E+ + D R S+ + + E ++ ++ K + +LK
Sbjct: 969 SAITLTSTWKEVKKIIKEDPRCIKF----SSSDRKKQREFEEYIRDKYITAKADFRTLLK 1024
Query: 568 DRGFCV--------EVNTAFEDFAHVISFDKRAAALD 596
+ F E + +D ++ DKR LD
Sbjct: 1025 ETKFITYRSKKLIQESDQHLKDVEKILQNDKRYLVLD 1061
Score = 53.9 bits (128), Expect = 6e-07
Identities = 112/553 (20%), Positives = 210/553 (37%), Gaps = 96/553 (17%)
Query: 184 QQLPQTLQPQPPQPQPDP-------PPV--PPGPTPVPTGLLEPEPGGSE----DCDVLE 230
Q PQTL P P P P PPV PP P+P G+ P PG + C ++
Sbjct: 334 QPHPQTLPPAVPHSVPQPTTAIPAFPPVMVPPFRVPLP-GMPIPLPGVAMMQIVSCPYVK 392
Query: 231 ATQPLEQGFLQ--------------QLEEGPSSSGQHQPQQEEEESKPEPERSGLSWSNR 276
+ G L + P++ E E K G ++
Sbjct: 393 TVATTKTGVLPGMAPPIVPMIHPQVAIAASPATLAGATAVSEWTEYKTA---DGKTYYYN 449
Query: 277 EKAKQAFKELLRDKAVPSNASWEQAMKMVVTDPRYSALPKLSE----KKQAFNAYKAQRE 332
+ ++ E + + + E+ +K + +P LP +E K++ K + +
Sbjct: 450 NRTLESTWE--KPQELKEKEKLEEKIKEPIKEPSEEPLPMETEEEDPKEEPIKEIKEEPK 507
Query: 333 KEEKEEARLRAKEAKQ---------------TLQHFLEQHERMTSTTRYRRAEQTFGELE 377
+EE E A++AK T + + T + + R + G +
Sbjct: 508 EEEMTEEEKAAQKAKPVATAPIPGTPWCVVWTGDERVFFYNPTTRLSMWDRPDDLIGRAD 567
Query: 378 VWAVVPERDRKEVYDDVLFFLAKKEKEQAKQLRRRNIQALKSILDGMSSVNFQTTWSQAQ 437
V ++ E K K E+ K+LR L + F + + +
Sbjct: 568 VDKIIQEPPHK------------KGMEELKKLRHPTPTMLS-----IQKWQFSMSAIKEE 610
Query: 438 QYLMDNPSFAQDHQLQNMDKEDALICFEEHIRALEREEEEERERARLRERRQQRKNREAF 497
Q LM+ + + + + ++D E A+E E + RERA + + ++
Sbjct: 611 QELMEEINEDEPVKAKKRKRDDNKDIDSEKEAAMEAEIKAARERAIVPLEARMKQ----- 665
Query: 498 QTFLDELHETGQLHSMSTWMELYPAVSTDVRFANMLGQPGSTPLDLFKFYVE-------- 549
F D L E G + + STW + + D R+ +L P +F YV+
Sbjct: 666 --FKDMLLERG-VSAFSTWEKELHKIVFDPRY--LLLNPKERK-QVFDQYVKTRAEEERR 719
Query: 550 ELKARFHDEKKIIKDILKDRGFCVEVNTAFEDFAHVISFDKRAAALDA-GNIKLTFNSLL 608
E K + K+ K ++++ F F +FA + D R A++ + + FN +
Sbjct: 720 EKKNKIMQAKEDFKKMMEEAKF--NPRATFSEFAAKHAKDSRFKAIEKMKDREALFNEFV 777
Query: 609 EKAEAREREREKEEARRMRRREAAFRSMLRQAVPALELGTAWEEVRERFVCDSAFEQITL 668
A AR++E+E + R + + F + L+ + W +V+++ D ++ +
Sbjct: 778 --AAARKKEKEDSKTRGEKIKSDFFELLSNHH---LDSQSRWSKVKDKVESDPRYKAVDS 832
Query: 669 ESERIRLFREFLQ 681
S R LF+++++
Sbjct: 833 SSMREDLFKQYIE 845
Score = 47.4 bits (111), Expect = 6e-05
Identities = 39/138 (28%), Positives = 62/138 (44%), Gaps = 7/138 (5%)
Query: 560 KIIKDILKDRGFCVEVNTAFEDFAHVISFDKRAAALDAGNIKLTFNSLLEKAEARERERE 619
K KD+L +RG V + +E H I FD R L+ K F+ + K A E RE
Sbjct: 664 KQFKDMLLERG--VSAFSTWEKELHKIVFDPRYLLLNPKERKQVFDQYV-KTRAEEERRE 720
Query: 620 KEEARRMRRREAAFRSMLRQAVPALELGTAWEEVRERFVCDSAFEQITLESERIRLFREF 679
K+ ++ + + F+ M+ +A + E + DS F+ I +R LF EF
Sbjct: 721 KKN--KIMQAKEDFKKMMEEA--KFNPRATFSEFAAKHAKDSRFKAIEKMKDREALFNEF 776
Query: 680 LQVLEQTECQHLHTKGRK 697
+ + E + T+G K
Sbjct: 777 VAAARKKEKEDSKTRGEK 794
>gi|155030232 proline, glutamic acid and leucine rich protein 1 [Homo
sapiens]
Length = 1130
Score = 73.2 bits (178), Expect = 1e-12
Identities = 75/284 (26%), Positives = 111/284 (39%), Gaps = 42/284 (14%)
Query: 9 PPGIPPPFPPMGLPPMSQRPPAIPPMPPGILPPMLPPMGAPPPLTQIPGMVPPMMPGMLM 68
P G+PP PP PP PP I P P P +P P L PG +PP P
Sbjct: 792 PEGLPPLPPP---PPSGATPPPIAPTGPPTASPPVPAKEEPEELPAAPGPLPPPPPP--P 846
Query: 69 PAVPVTAATAPGADTASSAVAGTGPPRALWSEHVAPDGRIYYYNADDKQSVWEKPSVLKS 128
P VP P G GPP + D + N+ D++ E+ +
Sbjct: 847 PPVPGPVTLPPPQLVPEGTPGGGGPPA------LEEDLTVININSSDEEEEEEEEEEEEE 900
Query: 129 KAELLLSQCPWKEYKSDTGKPYYYNNQSKESRW--------------------TRPKDLD 168
+ E + ++E + D + Y+ + +E + ++L+
Sbjct: 901 EEEEEEEE-DFEEEEEDE-EEYFEEEEEEEEEFEEEFEEEEGELEEEEEEEDEEEEEELE 958
Query: 169 DLEVLVKQEAAGKQQQQL--PQTLQPQPPQPQPDPPPVPPGPTPVPTGLLEPEPGGSED- 225
++E L A G+ ++ P TL P P P+ PP V P P P P LLE E G+E+
Sbjct: 959 EVEDLEFGTAGGEVEEGAPPPPTLPPALPPPE-SPPKVQPEPEPEPGLLLEVEEPGTEEE 1017
Query: 226 --CDVLEATQP---LEQGFLQQLEEGPSSSGQHQPQQEEEESKP 264
D P QG +++ E P++ Q EEE S P
Sbjct: 1018 RGADTAPTLAPEALPSQGEVEREGESPAAGPPPQELVEEEPSAP 1061
Score = 62.4 bits (150), Expect = 2e-09
Identities = 81/305 (26%), Positives = 117/305 (38%), Gaps = 43/305 (14%)
Query: 2 MPPPFMPPPGIPPPFPPMGLPPMSQRPPAIPPMP-PGILPPMLP-PMGAPPPLT------ 53
+PPP P P PPF P G P P+ PMP G +P P P P P T
Sbjct: 651 VPPPEAPSPFRAPPFHPPGPMPSVGSMPSAGPMPSAGPMPSAGPVPSARPGPPTTANHLG 710
Query: 54 -QIPGMV---PPMMPGMLMPAVPVTAATAPGADTASSAVAGTGPPRALWSEHVAPDGRIY 109
+PG+V P ++PG P + S T PP + V ++
Sbjct: 711 LSVPGLVSVPPRLLPG---PENHRAGSNEDPILAPSGTPPPTIPPDETFGGRVPRPAFVH 767
Query: 110 YYNADDKQSVWEKPSVLKSKAELLLSQCPWKEYKSDTGKPYYYNNQSKESRWTRPKDLDD 169
Y DK+ + L+S ++ + P G P S T P
Sbjct: 768 Y----DKEEASDVEISLESDSDDSVVIVP-------EGLPPL--PPPPPSGATPPPIAPT 814
Query: 170 LEVLVKQEAAGKQQ-QQLPQTLQPQPPQPQPDPPPVPPGPTPVPTGLLEPE--PGG---- 222
K++ ++LP P PP P P PPPV PGP +P L PE PGG
Sbjct: 815 GPPTASPPVPAKEEPEELPAAPGPLPP-PPPPPPPV-PGPVTLPPPQLVPEGTPGGGGPP 872
Query: 223 --SEDCDVLEATQPLEQGFLQQLEEGPSSSGQHQPQQEEEESKPEPERSGLSWSNREKAK 280
ED V+ E ++ EE + + ++EEE+ + E E + E+ +
Sbjct: 873 ALEEDLTVININSSDE----EEEEEEEEEEEEEEEEEEEEDFEEEEEDEEEYFEEEEEEE 928
Query: 281 QAFKE 285
+ F+E
Sbjct: 929 EEFEE 933
Score = 33.1 bits (74), Expect = 1.1
Identities = 64/285 (22%), Positives = 92/285 (32%), Gaps = 53/285 (18%)
Query: 594 ALDAGNIKLTFNSLLEKAEAREREREKEEARRMRRREAAFRSMLRQAVPALELGTAWEEV 653
AL+ + NS E+ E E E E+EE E + E EE
Sbjct: 873 ALEEDLTVININSSDEEEEEEEEEEEEEE-----EEEEEEEDFEEEEEDEEEYFEEEEEE 927
Query: 654 RERFVCDSAFEQITLESERIRLFREFLQVLEQTECQHLHTKGRKHGRKGKKHHHKRSHSP 713
E F + E+ LE E E + LE+ E T
Sbjct: 928 EEEFEEEFEEEEGELEEEEEEEDEEEEEELEEVEDLEFGT-------------------- 967
Query: 714 SGSESEEEELPP----PSLRPPKRRRRNPSESGSEPSSSLDSVESGGAALGGRGSPSSHL 769
+G E EE PP P+L PP+ + E EP L+ E G +
Sbjct: 968 AGGEVEEGAPPPPTLPPALPPPESPPKVQPEPEPEPGLLLEVEEPG----------TEEE 1017
Query: 770 LGADHGLRKAKKPKKKTKKRRHKSNSPESETDPEEKAGKESD------EKEQEQDKDREL 823
GAD A + + + SP + P+E +E E+E E D+
Sbjct: 1018 RGADTAPTLAPEALPSQGEVEREGESPAAGPPPQELVEEEPSAPPTLLEEETEDGSDKVQ 1077
Query: 824 QQAELPNRSPGFGIKKEKTGWDTSESELSEGELERRRRTLLQQLD 868
E P +E+ +T L E E + L +D
Sbjct: 1078 PPPETP--------AEEEMETETEAEALQEKEQDDTAAMLADFID 1114
Score = 30.8 bits (68), Expect = 5.7
Identities = 33/149 (22%), Positives = 55/149 (36%), Gaps = 5/149 (3%)
Query: 725 PPSLRPPKRRRRNPSESGSEPSSSLDSVESGGAALGGRGSPSSHLL--GADHGLRKAKKP 782
PP+ PP + P E + P G P L+ G G
Sbjct: 816 PPTASPPVPAKEEPEELPAAPGPLPPPPPPPPPVPGPVTLPPPQLVPEGTPGGGGPPALE 875
Query: 783 KKKTKKRRHKSNSPESETDPEEKAGKESDEKEQ---EQDKDRELQQAELPNRSPGFGIKK 839
+ T + S+ E E + EE+ +E +E+E+ E+++D E E F +
Sbjct: 876 EDLTVININSSDEEEEEEEEEEEEEEEEEEEEEDFEEEEEDEEEYFEEEEEEEEEFEEEF 935
Query: 840 EKTGWDTSESELSEGELERRRRTLLQQLD 868
E+ + E E E E E ++ L+
Sbjct: 936 EEEEGELEEEEEEEDEEEEEELEEVEDLE 964
>gi|148746195 trichohyalin [Homo sapiens]
Length = 1943
Score = 72.4 bits (176), Expect = 2e-12
Identities = 158/800 (19%), Positives = 306/800 (38%), Gaps = 116/800 (14%)
Query: 120 WEKPSVLKSKAELLLSQCPWKEYKSDTGKPYYYNNQSKESRWTRPKDLD-DLEVLVKQEA 178
+ K L+ + E LL + P K + Q +E + ++L + E L+++E
Sbjct: 1080 YRKEEELQQEEEQLLREEPEKRRR-----------QERERQCREEEELQQEEEQLLREER 1128
Query: 179 AGKQQQQLPQTLQPQPPQPQPDPPPVPPGPTPVPTGLLEPEPGGSEDCDVLEATQPLEQG 238
+++Q+L + + + Q + + EPE ++ + Q E+
Sbjct: 1129 EKRRRQELERQYREEEEVQQEEEQLLRE----------EPEKRRRQELE----RQYREEE 1174
Query: 239 FLQQLEEGPSSSGQHQPQQEEEESKPEPERSGLSWSNREKAKQAFKELLRDKAVPSNASW 298
LQQ EE Q + +QE E E E R+K KQ +++ D+ W
Sbjct: 1175 ELQQEEEQLLREEQEKRRQERERQYREEEEL-----QRQKRKQRYRD--EDQRSDLKWQW 1227
Query: 299 EQAMKMVVTDPRYSALPKLSEKKQAFNAYKAQREKEE---KEEARLRAKEAKQTLQHFL- 354
E + V D + Y RE E+ E+++LR ++++Q LQH L
Sbjct: 1228 EPEKENAVRDNK---------------VYCKGRENEQFRQLEDSQLRDRQSQQDLQHLLG 1272
Query: 355 --EQHERMTSTTRYRRAEQTFG-----ELEVWAVVPERDRKEVYDDVLFFLAKKEK---- 403
++ +R R+++ ++ F E E RDRK + L ++EK
Sbjct: 1273 EQQERDREQERRRWQQRDRHFPEEEQLEREEQKEAKRRDRKSQEEKQLLREEREEKRRRQ 1332
Query: 404 -------EQAKQLRRRNIQAL-KSILDGMSSVNFQTTWSQAQQYLMDNPSFAQDHQLQNM 455
E+ + L+ R Q L + D Q +++L ++ +L+
Sbjct: 1333 ETDRKFREEEQLLQEREEQPLRRQERDRKFREEELRHQEQGRKFL------EEEQRLRRQ 1386
Query: 456 DKEDALICFEEHIRALEREEEEERERAR-LRERRQQRKNREAFQTFLDELHETGQLHSMS 514
++E + E+ +R ERE++ ++R R RE QQ +E + F +E + +
Sbjct: 1387 ERERKFLKEEQQLRCQEREQQLRQDRDRKFREEEQQLSRQERDRKFREEEQQVRRQERER 1446
Query: 515 TWMELYPAVSTDVRFANMLGQPGSTPLDLFKFYVEELKARFHDEKKIIKDILKDRGFCVE 574
++E + + + + + + +E +F +E++ ++ +DR F +
Sbjct: 1447 KFLEEEQQLRQERHRKFREEEQLLQEREEQQLHRQERDRKFLEEEQQLRRQERDRKFREQ 1506
Query: 575 VNTAFEDFAHVISFDKRAAALDAGNIKLTFNSLLEKAEA-------REREREKEEARRMR 627
+ E + +++ L L + E R+R+ +EE R
Sbjct: 1507 ELRSQEPERKFLEEEQQLHRQQRQRKFLQEEQQLRRQERGQQRRQDRDRKFREEEQLRQE 1566
Query: 628 RREAAFRSMLRQAVPALELGTAWEEVRERFVCDSAFE------QITLESERIRLFREFLQ 681
R E R LE + +ER + + Q L ER R FRE Q
Sbjct: 1567 REEQQLSRQERDRKFRLEEQKVRRQEQERKFMEDEQQLRRQEGQQQLRQERDRKFREDEQ 1626
Query: 682 VLEQTECQHLHTKGR-------KHGRKGKKHHHKRSHSPSGSESEEEELPPPSLRPPKRR 734
+L++ E Q LH + R + + ++ + H EEE+L RR
Sbjct: 1627 LLQEREEQQLHRQERDRKFLEEEPQLRRQEREQQLRHDRDRKFREEEQLLQEGEEQQLRR 1686
Query: 735 RRNPSESGSEPSSSLDSVESGGAALGGRGSPSSHLLGADHGLRKAKKPKKKTKKRRHKSN 794
+ + E R L + LR+ + +K ++ + +
Sbjct: 1687 QERDRKFREEEQQL------------RRQERERKFLQEEQQLRRQELERKFREEEQLRQE 1734
Query: 795 SPESETDPEEKAGKESDEKEQEQDKDRELQQAELPNRSPGFGIKKEKTGWDTSESELSEG 854
+ + + +E+ K +E++ +RE QQ R F ++E+ + E +L
Sbjct: 1735 TEQEQLRRQERYRKILEEEQLR--PEREEQQLRRQERDRKFR-EEEQLRQEREEQQLRSQ 1791
Query: 855 ELERRRR---TLLQQLDDHQ 871
E +R+ R L Q+ ++ Q
Sbjct: 1792 ESDRKFREEEQLRQEREEQQ 1811
Score = 65.9 bits (159), Expect = 2e-10
Identities = 123/625 (19%), Positives = 257/625 (41%), Gaps = 56/625 (8%)
Query: 252 QHQPQQEEEESKPEPERSGLSWSNREKAKQAFKELLRDKAVPSNASWEQAMKMVVTDPRY 311
+H P++E+ E + + E R++ Q K+LLR++ E+ + TD ++
Sbjct: 1291 RHFPEEEQLEREEQKEAK-----RRDRKSQEEKQLLREER-------EEKRRRQETDRKF 1338
Query: 312 SALPKLSEKKQAFNAYKAQREKEEKEEARLRAKEAKQTLQHFLEQHERMTSTTRYRRAEQ 371
+L ++++ + +R+++ +EE ++ ++ FLE+ +R+ R + E+
Sbjct: 1339 REEEQLLQEREEQPLRRQERDRKFREEELRHQEQGRK----FLEEEQRL----RRQERER 1390
Query: 372 TFGELEVWAVVPERDRKEVYDDVLFFLAKKEKEQAKQLRRRNIQALKSILDGMSSVNFQT 431
F + E ER+++ D F ++E++ ++Q R R + + + +
Sbjct: 1391 KFLKEEQQLRCQEREQQLRQDRDRKF-REEEQQLSRQERDRKFREEEQQVRRQER---ER 1446
Query: 432 TWSQAQQYLMD--NPSFAQDHQLQNMDKEDALICFEEHIRALEREEEEERERARLRERRQ 489
+ + +Q L + F ++ QL +E L E + LE E++ R+ + R Q
Sbjct: 1447 KFLEEEQQLRQERHRKFREEEQLLQEREEQQLHRQERDRKFLEEEQQLRRQERDRKFREQ 1506
Query: 490 QRKNREAFQTFLDELHETGQLHSMSTWMELYPAVSTDVRFANMLGQPGSTPLDLFKFYVE 549
+ +++E + FL+E + + +++ + R GQ D KF E
Sbjct: 1507 ELRSQEPERKFLEEEQQLHRQQRQRKFLQEEQQLRRQER-----GQQRRQDRDR-KFREE 1560
Query: 550 ELKARFHDEKKIIKDILKDRGFCVEVNTAF-EDFAHVISFDKRAAALDAGNIKLTFN--- 605
E + +E+++ + +DR F +E ++ D++ G +L
Sbjct: 1561 EQLRQEREEQQLSRQE-RDRKFRLEEQKVRRQEQERKFMEDEQQLRRQEGQQQLRQERDR 1619
Query: 606 ------SLLEKAEAREREREKEEARRMRRREAAFRSMLRQAVPALELGTAWEEVRERFVC 659
LL++ E ++ R++ + R+ E R R+ + + E E +
Sbjct: 1620 KFREDEQLLQEREEQQLHRQERD-RKFLEEEPQLRRQEREQQLRHDRDRKFRE--EEQLL 1676
Query: 660 DSAFEQITLESERIRLFREFLQVLEQTECQHLHTKGRKHGRKGKKHHHKRSHSPSGSESE 719
EQ ER R FRE Q L + E + + + R+ + R E+E
Sbjct: 1677 QEGEEQQLRRQERDRKFREEEQQLRRQERERKFLQEEQQLRRQELERKFREEEQLRQETE 1736
Query: 720 EEELPPPSLRPPKRRRRNPSESGSEPSSSLDSVESGGAALGGRGSPSSHLLGADHGLRKA 779
+E+L R +R R+ E P + R + LR
Sbjct: 1737 QEQL-----RRQERYRKILEEEQLRPEREEQQLRRQERDRKFREEEQLRQEREEQQLRSQ 1791
Query: 780 KKPKKKTKKRRHKSNSPESETDPEEKAGKESDEKEQEQDKDRE---LQQAELPNRSPGFG 836
+ +K ++ + + E + P+++ GK E+EQ Q +++E Q+ + R+
Sbjct: 1792 ESDRKFREEEQLRQEREEQQLRPQQRDGKYRWEEEQLQLEEQEQRLRQERDRQYRAEEQF 1851
Query: 837 IKKEKTGWDTSESELSEGELERRRR 861
+EK+ E EL + E ++RR+
Sbjct: 1852 ATQEKS--RREEQELWQEEEQKRRQ 1874
Score = 64.3 bits (155), Expect = 5e-10
Identities = 133/662 (20%), Positives = 261/662 (39%), Gaps = 57/662 (8%)
Query: 240 LQQLEEGPSSSGQHQPQQEEEESKPEPERSGLSWSNREKAKQAFKELLRDKAVPSNASWE 299
L++ +E +H+ ++ E+ K E E W RE+ + ++ R +
Sbjct: 425 LRREQEEERHEQKHEQERREQRLKREQEERR-DWLKREEETERHEQERR----------K 473
Query: 300 QAMKMVVTDPRYSALPKLSEKK----QAFNAYKAQREKEEKEEARLRAKEAKQTLQHFLE 355
Q +K + R KL E++ Q + +RE+EE+ E RL+ +E ++ LQ L
Sbjct: 474 QQLKRDQEEERRERWLKLEEEERREQQERREQQLRREQEERREQRLKRQEEEERLQQRLR 533
Query: 356 QHERMTSTTRYRRAEQTFGELEVWAVVPERDR--KEVYDDVLFFLAKKEKEQAKQ-LRRR 412
+++ RR + E E R++ K ++ L K+E+E+ +Q L+R
Sbjct: 534 SEQQLRREQEERREQLLKREEEKRLEQERREQRLKREQEERRDQLLKREEERRQQRLKRE 593
Query: 413 NIQALKSILDGMSSVNFQTTWSQAQQYLMDNPSFAQDHQLQNMDKED-------ALICFE 465
+ L+ L + + Q+ + P + QL ++++ E
Sbjct: 594 QEERLEQRLKREEVERLEQEERREQRLKREEPEEERRQQLLKSEEQEERRQQQLRREQQE 653
Query: 466 EHIRALEREEEEERERARL-RERRQQRKNREAFQTFLDELHETGQLHSMSTWMELYPAVS 524
+ L+REEEEER RL RE ++R+ +E + ++ E ++ S +
Sbjct: 654 RREQRLKREEEEERLEQRLKREHEEERREQELAEEEQEQARE--RIKSRIPKWQWQLESE 711
Query: 525 TDVRFANMLGQPGSTPLDLFKFYVEELKARFHDEKKIIKDILKDRGFCVEVNTAFEDFAH 584
D R + + +P + EE + R E + ++ R E DF
Sbjct: 712 ADARQSKVYSRPRKQEGQRRRQEQEEKRRRRESELQWQEEERAHRQQQEEEQR--RDFTW 769
Query: 585 VISFDKRAAALDAGNIKLTFNSLLE-------KAEARER-------EREKEEARRMRRRE 630
++++ + G +L+ L +AE R++ E E++E RR +RRE
Sbjct: 770 QWQAEEKS---ERGRQRLSARPPLREQRERQLRAEERQQREQRFLPEEEEKEQRRRQRRE 826
Query: 631 AAFRSMLRQAVPALELGTAWEEVRERFVCDSAFE-QITLESERIRLFREFLQVLEQTECQ 689
+ L+ ++++E D E Q S+ R +++ LE+ +
Sbjct: 827 REKELQFLEEEEQLQRRERAQQLQEEE--DGLQEDQERRRSQEQRRDQKWRWQLEEERKR 884
Query: 690 HLHTKGRKHGRKGKKHHHKRSHSPSGSESEEEELPPPSLRPPKRRRRNPSESGSEPSSSL 749
HT K + + ++ E + EE + +R+ R + E L
Sbjct: 885 RRHTLYAKPALQEQLRKEQQLLQEEEEELQREEREKRRRQEQERQYREEEQLQQEEEQLL 944
Query: 750 -DSVESGGAALGGRGSPSSHLLGADHGLRKAKKPKKKTKKRRHKSNSPESE-TDPEEKAG 807
+ E R L ++P+K+ ++ R K E E EE+
Sbjct: 945 REEREKRRRQERERQYRKDKKLQQKEEQLLGEEPEKRRRQEREKKYREEEELQQEEEQLL 1004
Query: 808 KESDEKEQEQDKDRELQQAELPNRSPGFGIKKEKTGWDTSESELSEGELERRRRTLLQQL 867
+E EK + Q+ +R+ ++ + + +++E+ + L E E + R LQQ
Sbjct: 1005 REEREKRRRQEWERQYRKKDELQQEEEQLLREER-----EKRRLQERERQYREEEELQQE 1059
Query: 868 DD 869
++
Sbjct: 1060 EE 1061
Score = 58.5 bits (140), Expect = 3e-08
Identities = 127/663 (19%), Positives = 266/663 (40%), Gaps = 61/663 (9%)
Query: 229 LEATQPLEQGFLQQLEEGPSSSGQHQPQQEEEESKPEPERSGLSWSNREKAKQAFKELL- 287
L+ +P Q LQ+ EE + + ++E +E + + +R R K ++ +E
Sbjct: 260 LQEEEPQRQRELQEEEEQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQE 319
Query: 288 -----RDKAVPSNASWEQAMKMVVTDPRYSALPKLSEKKQAFNAYKAQREKEEKEEARLR 342
+++ EQ ++ + R L + E+++ + ++E+E +E+ R
Sbjct: 320 ERREQQERREQQEERREQQLRREQEERREQQLRREQEEERREQQLRREQEEERREQQLRR 379
Query: 343 AKEAKQTLQHFLEQHERMTSTTRYRRAEQTFGELEVWAVVPERDRKEVYDDVLFFLAKKE 402
++ ++ Q L + +++ + RR +Q E ++ R+++ + L ++E
Sbjct: 380 EQQLRREQQ--LRREQQLRREQQLRREQQLRREQQL-----RREQQLRREQQLRREQEEE 432
Query: 403 KEQAKQLRRRNIQALKSILDGMSSVNFQTTWSQAQQYLMDNPSFAQDHQLQNMDKEDALI 462
+ + K + R Q LK + + W + ++ + + QL+ +E
Sbjct: 433 RHEQKHEQERREQRLKREQEE------RRDWLKREEETERHEQERRKQQLKRDQEE---- 482
Query: 463 CFEEHIRALEREEEEERERARLRERRQQRKNREAFQTFLDELHETGQLHSMSTWMELYPA 522
E R L+ EEEE RE+ RE++ +R+ E + L E +L E
Sbjct: 483 --ERRERWLKLEEEERREQQERREQQLRREQEERREQRLKRQEEEERLQQRLR-SEQQLR 539
Query: 523 VSTDVRFANMLGQPGSTPLD------LFKFYVEELKARF--HDEKKIIKDILKDRGFCVE 574
+ R +L + L+ K EE + + +E++ + + +++ +E
Sbjct: 540 REQEERREQLLKREEEKRLEQERREQRLKREQEERRDQLLKREEERRQQRLKREQEERLE 599
Query: 575 VNTAFEDFAHVISFDKRAAALDAGNIKLTFNSLLEKAEAREREREKEEARRMRRREAAFR 634
E+ + ++R L + L K+E +E ER +++ RR ++ R
Sbjct: 600 QRLKREEVERLEQEERREQRLKREEPEEERRQQLLKSEEQE-ERRQQQLRREQQERREQR 658
Query: 635 SMLRQAVPALELGTAWEEVRERFVCDSAFEQITLESERI--RLFREFLQVLEQTECQHLH 692
+ LE E ER + A E+ ERI R+ + Q+ + + +
Sbjct: 659 LKREEEEERLEQRLKREHEEERREQELAEEEQEQARERIKSRIPKWQWQLESEADARQSK 718
Query: 693 TKGRKHGRKGKKHHHKRSHSPSGSESE----EEELPPPSLRPPKRRRRNPSESGSEPSSS 748
R ++G++ ++ ESE EEE + ++RR + +E S
Sbjct: 719 VYSRPRKQEGQRRRQEQEEKRRRRESELQWQEEERAHRQQQEEEQRRDFTWQWQAEEKS- 777
Query: 749 LDSVESGGAALGGR---GSPSSHLLGADHGLRKAKK-----PKKKTKKRRHKSNSPESET 800
E G L R L A+ ++ ++ +K+ ++R+ + E +
Sbjct: 778 ----ERGRQRLSARPPLREQRERQLRAEERQQREQRFLPEEEEKEQRRRQRREREKELQF 833
Query: 801 DPEEKAGKESDEKEQEQDKDRELQQAELPNRSPGFGIKKEKTGWDTSESELSEGELERRR 860
EE+ + + +Q Q+++ LQ+ + RS + +K W E E +RRR
Sbjct: 834 LEEEEQLQRRERAQQLQEEEDGLQEDQERRRSQE-QRRDQKWRWQLEE------ERKRRR 886
Query: 861 RTL 863
TL
Sbjct: 887 HTL 889
Score = 55.8 bits (133), Expect = 2e-07
Identities = 134/701 (19%), Positives = 256/701 (36%), Gaps = 84/701 (11%)
Query: 230 EATQPLEQGFLQQLEEGPSSSGQHQPQQEEEESKPEPERSGLSWSNREKAKQAFKELLRD 289
E Q E+ L+ EE Q + +Q ++ K + + L EK ++ +E
Sbjct: 934 EQLQQEEEQLLR--EEREKRRRQERERQYRKDKKLQQKEEQLLGEEPEKRRRQEREKKYR 991
Query: 290 KAVPSNASWEQAMKMVVTDPRYSALPKLSEKKQAFNAYKAQREKEEKEEARLRAKEAKQT 349
+ EQ ++ R + KK + Q +EE+E+ RL+ +E +
Sbjct: 992 EEEELQQEEEQLLREEREKRRRQEWERQYRKKDELQQEEEQLLREEREKRRLQERERQYR 1051
Query: 350 LQHFLEQHE------------RMTSTTRYRRAEQTFGELE-VWAVVPERDRKEVYDDVLF 396
+ L+Q E R +YR+ E+ E E + PE+ R++ +
Sbjct: 1052 EEEELQQEEEQLLGEERETRRRQELERQYRKEEELQQEEEQLLREEPEKRRRQERERQCR 1111
Query: 397 FLAKKEKEQAKQLRRRNIQALKSILDGMSSVNFQTTWSQAQQYLMDNPSFAQDHQLQNM- 455
+ ++E+ + LR + + L+ + + +Q L + P + +L+
Sbjct: 1112 EEEELQQEEEQLLREEREKRRRQELERQYREE-EEVQQEEEQLLREEPEKRRRQELERQY 1170
Query: 456 -------DKEDALICFEEHIRALEREEEEERERARLRERRQQRKNREAFQTFLDELHETG 508
+E+ L+ E+ R ERE + E R++R+QR E ++ L E
Sbjct: 1171 REEEELQQEEEQLLREEQEKRRQERERQYREEEELQRQKRKQRYRDEDQRSDLKWQWEPE 1230
Query: 509 QLHSMSTWMELYPAVSTDVRFANMLG---QPGSTPLDLFKFYVEELKARFHDEKKIIKDI 565
+ +++ ++Y + +F + + + DL E+ + E++ +
Sbjct: 1231 KENAVRD-NKVYCKGRENEQFRQLEDSQLRDRQSQQDLQHLLGEQQERDREQERRRWQQ- 1288
Query: 566 LKDRGFCVEVNTAFEDFAHVISFDKRAAALDAGNIKLTFNSLLEKAEAREREREKEEARR 625
+DR F E E+ K A D K L + E E+ R +E R+
Sbjct: 1289 -RDRHFPEEEQLEREE-------QKEAKRRDR---KSQEEKQLLREEREEKRRRQETDRK 1337
Query: 626 MRRREAAFRSMLRQAVPALELGTAWEEVRERFVCDSAFEQITLESERIR---LFREFLQV 682
R E + Q + E + E E + E +R+R R+FL+
Sbjct: 1338 FREEEQLLQEREEQPLRRQERDRKFRE--EELRHQEQGRKFLEEEQRLRRQERERKFLKE 1395
Query: 683 LEQTECQHLHTKGRK-HGRKGKKHHHKRSHSPSGSESEEEELPPPSLRPPKRRRRNPSES 741
+Q CQ + R+ RK ++ + S + EEE +R +R R+ E
Sbjct: 1396 EQQLRCQEREQQLRQDRDRKFREEEQQLSRQERDRKFREEE---QQVRRQERERKFLEEE 1452
Query: 742 GSEPSSSLDSVESGGAALGGRGSPSSH-------LLGADHGLRKAKKPKK---------- 784
L R H L + LR+ ++ +K
Sbjct: 1453 QQLRQERHRKFREEEQLLQEREEQQLHRQERDRKFLEEEQQLRRQERDRKFREQELRSQE 1512
Query: 785 ------KTKKRRHKSNSPESETDPEEKAGKESDEKEQEQDKD------------RELQQA 826
+ +++ H+ E++ ++ +++ QD+D RE QQ
Sbjct: 1513 PERKFLEEEQQLHRQQRQRKFLQEEQQLRRQERGQQRRQDRDRKFREEEQLRQEREEQQL 1572
Query: 827 ELPNRSPGFGIKKEKTGWDTSESELSEGELERRRRTLLQQL 867
R F ++++K E + E E + RR+ QQL
Sbjct: 1573 SRQERDRKFRLEEQKVRRQEQERKFMEDEQQLRRQEGQQQL 1613
Score = 50.4 bits (119), Expect = 7e-06
Identities = 108/579 (18%), Positives = 221/579 (38%), Gaps = 54/579 (9%)
Query: 319 EKKQAFNAYKAQREKEEKEEARLRAKEAKQTLQHFLEQ---HERMTSTTRYRRAEQTFGE 375
E ++ F Q E+E + R + +E ++ L EQ ER+ R RR E+ + +
Sbjct: 117 EDQRRFEPRDRQLEEEPGQRRRQKRQEQERELAEGEEQSEKQERLEQRDRQRRDEELWRQ 176
Query: 376 LEVWAVVPERDRKEVYDDVLFFLAKKEKEQ---AKQLRRRNI------------QALKSI 420
+ W ER+ + ++ L E E+ +QLRRR + Q +
Sbjct: 177 RQEWQ---EREERRAEEEQLQSCKGHETEEFPDEEQLRRRELLELRRKGREEKQQQRRER 233
Query: 421 LDGMSSVNFQTTWSQAQQYLMDNPSFAQDHQLQNM----DKEDALICFEEHIRALEREEE 476
D + + W + + L Q+ + Q ++E+ L E ER+EE
Sbjct: 234 QDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQRELQEEEEQLRKLERQELRRERQEE 293
Query: 477 EERERARLRERRQQRKNREAFQTFLDELHETGQ-LHSMSTWMELYPAVSTDVRFANMLGQ 535
E++++ RE++ +RK E + +E E + E + R L +
Sbjct: 294 EQQQQRLRREQQLRRKQEEERREQQEERREQQERREQQEERREQQLRREQEERREQQLRR 353
Query: 536 PGSTPLDLFKFYVEELKARFHDEKKIIKDILKDRGFCVEVNTAFEDFAHVISFDKRAAAL 595
+ E+ + R + + + + +++ E E +R L
Sbjct: 354 EQEEERREQQLRREQEEERREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQL 413
Query: 596 DAGNIKLTFNSLLEKAEAREREREKEEAR---RMRRREAAFRSMLRQAVPALELGTAWEE 652
L + E E++ E+ R R++R + R L++ EE
Sbjct: 414 RREQQLRREQQLRREQEEERHEQKHEQERREQRLKREQEERRDWLKR-----------EE 462
Query: 653 VRERFVCDSAFEQITLESERIRLFREFLQVLEQTECQHLHTKGRKHGRKGKKHHHKRSHS 712
ER + +Q+ + E R R +L++ E+ + + ++ R+ ++ +R
Sbjct: 463 ETERHEQERRKQQLKRDQEEERRER-WLKLEEEERREQQERREQQLRREQEERREQRL-- 519
Query: 713 PSGSESEEEELPPPSLRPPKRRRRNPSESGSEPSSSLDSVESGGAALGGRGSPSSHLLGA 772
EEEE LR ++ RR E + L E R L
Sbjct: 520 ---KRQEEEERLQQRLRSEQQLRREQEERREQ---LLKREEEKRLEQERR----EQRLKR 569
Query: 773 DHGLRKAKKPKKKTKKRRHKSNSPESETDPEEKAGKESDEKEQEQDKDRELQQAELPNRS 832
+ R+ + K++ ++R+ + + E + +E + EQE+ +++ L++ E P
Sbjct: 570 EQEERRDQLLKREEERRQQRLKREQEERLEQRLKREEVERLEQEERREQRLKREE-PEEE 628
Query: 833 PGFGIKKEKTGWDTSESELSEGELERRRRTLLQQLDDHQ 871
+ K + + + +L + ERR + L ++ ++ +
Sbjct: 629 RRQQLLKSEEQEERRQQQLRREQQERREQRLKREEEEER 667
Score = 50.4 bits (119), Expect = 7e-06
Identities = 119/663 (17%), Positives = 250/663 (37%), Gaps = 94/663 (14%)
Query: 217 EPEPGGSEDCDVLEATQPLEQGFLQQLEEGPSSSGQHQPQQEEEESKPEP--ERSGLSWS 274
EPE E L ++ E+ QQL + + ++EEEE + E +R
Sbjct: 624 EPE---EERRQQLLKSEEQEERRQQQLRREQQERREQRLKREEEEERLEQRLKREHEEER 680
Query: 275 NREKAKQAFKELLRDKAVPSNASWEQAMKMVVTDPRYSALPKLSEKKQAFNAYKAQREKE 334
++ + +E R++ W+ ++ D R S + K++ + Q EK
Sbjct: 681 REQELAEEEQEQARERIKSRIPKWQWQLESEA-DARQSKVYSRPRKQEGQRRRQEQEEKR 739
Query: 335 EKEEARLRAKEAKQTLQHFLEQHERMTSTTRYRRAEQTF-GELEVWAVVPERDRKE---- 389
+ E+ L+ +E ++ + E+ +R T +++ E++ G + A P R+++E
Sbjct: 740 RRRESELQWQEEERAHRQQQEEEQRRDFTWQWQAEEKSERGRQRLSARPPLREQRERQLR 799
Query: 390 ----VYDDVLFFLAKKEKEQAKQLRRRNIQALKSILDGMSSVNFQTTWSQAQQYLMDNPS 445
+ F ++EKEQ ++ RR + L Q+L +
Sbjct: 800 AEERQQREQRFLPEEEEKEQRRRQRREREKEL--------------------QFLEEEEQ 839
Query: 446 FAQDHQLQNMDKEDALICFEEHIRALEREEEEERERARLRE-RRQQRKNREAFQTFLDEL 504
+ + Q + +E+ + ++ R + + +++ R +L E R+++R A ++L
Sbjct: 840 LQRRERAQQLQEEEDGLQEDQERRRSQEQRRDQKWRWQLEEERKRRRHTLYAKPALQEQL 899
Query: 505 HETGQLHSMSTWMELYPAVSTDVRFANMLGQPGSTPLDLFKFYVEELKARFHDEKKIIKD 564
+ QL E + + R + + Y EE + + +E+ + ++
Sbjct: 900 RKEQQL-----LQEEEEELQREEREKRRRQEQE-------RQYREEEQLQQEEEQLLREE 947
Query: 565 ILKDRGFCVEVNTAFEDFAHVISFDKRAAALDAGNIKLTFNSLLEKAEAREREREKEEAR 624
K R ++ DK+ ++ LL + + R +E+E+
Sbjct: 948 REKRRR---------QERERQYRKDKK--------LQQKEEQLLGEEPEKRRRQEREKKY 990
Query: 625 RMRRREAAFRSMLRQAVPALELGTAWE-EVRERFVCDSAFEQITLES-ERIRLFREFLQV 682
R L + WE + R++ EQ+ E E+ RL Q
Sbjct: 991 REEEELQQEEEQLLREEREKRRRQEWERQYRKKDELQQEEEQLLREEREKRRLQERERQY 1050
Query: 683 LEQTECQHLHTK--GRKHGRKGKKHHHKRSHSPSGSESEEEELPPPSLRPPKRRRRNPSE 740
E+ E Q + G + + ++ ++ + EEE+L P++RRR E
Sbjct: 1051 REEEELQQEEEQLLGEERETRRRQELERQYRKEEELQQEEEQL---LREEPEKRRRQERE 1107
Query: 741 SGSEPSSSLDSVESGGAALGGRGSPSSHLLGADHGLRKAKKPKKKTKKRRHKSNSPESET 800
L E L + ++ K++ ++ + E
Sbjct: 1108 RQCREEEELQQEE--------------------EQLLREEREKRRRQELERQYREEEEVQ 1147
Query: 801 DPEEKAGKESDEKEQEQDKDRELQQAELPNRSPGFGIK--KEKTGWDTSESELSEGELER 858
EE+ +E EK + Q+ +R+ ++ E + ++ +EK + E EL+R
Sbjct: 1148 QEEEQLLREEPEKRRRQELERQYREEEELQQEEEQLLREEQEKRRQERERQYREEEELQR 1207
Query: 859 RRR 861
++R
Sbjct: 1208 QKR 1210
Score = 47.4 bits (111), Expect = 6e-05
Identities = 144/777 (18%), Positives = 282/777 (36%), Gaps = 122/777 (15%)
Query: 114 DDKQSVWEK-PSVLKSKAELLLSQCPWKEYKSDTGKPYYYNNQSKESRWTRPKDLDDLEV 172
++++ W K +VL+ + E L + P ++ + + + +E R R ++ +
Sbjct: 240 EEEEKEWRKRETVLRKEEEKLQEEEPQRQRELQEEEEQLRKLERQELRRERQEEEQQQQR 299
Query: 173 LVKQEAAGKQQQQLPQTLQPQPPQPQPDPPPVPPGPTPVPTGLLEPEPGGSEDCDVLEAT 232
L +++ ++Q++ + Q + + Q E + E E
Sbjct: 300 LRREQQLRRKQEEERREQQEERREQQERR---------------EQQEERREQQLRREQE 344
Query: 233 QPLEQGFLQQLEEGPSSSGQHQPQQEEEESKPEPERSGLSWSNREKAKQAFKELLRDKAV 292
+ EQ ++ EE + Q ++E+EE + E + RE+ + ++L R++ +
Sbjct: 345 ERREQQLRREQEE---ERREQQLRREQEEERREQQLRREQQLRREQQLRREQQLRREQQL 401
Query: 293 PSNASW--EQAMKMVVTDPRYSALPKLSEKKQAFNAY----KAQREKEEKEEARLRAKEA 346
EQ ++ R L + E+++ + + QR K E+EE R K
Sbjct: 402 RREQQLRREQQLRREQQLRREQQLRREQEEERHEQKHEQERREQRLKREQEERRDWLKRE 461
Query: 347 KQTLQHFLEQHERMTSTTRYRRAEQTFGELEVWAVVPERDRKEVYDDVLFFLAKKEKEQA 406
++T +H EQ R R + E+ E W + E +R+E + ++E++
Sbjct: 462 EETERH--EQERRKQQLKRDQEEERR----ERWLKLEEEERREQQE-------RREQQLR 508
Query: 407 KQLRRRNIQALKSILDGMSSVNFQTTWSQAQQYLMDNPSFAQDHQLQNMDKEDALICFEE 466
++ R Q LK Q + QQ L ++ + E
Sbjct: 509 REQEERREQRLKR----------QEEEERLQQRLRSEQQLRREQE-------------ER 545
Query: 467 HIRALEREEEEERERARLRERRQQRKNREAFQTFLDELHETGQLHSMSTWMELYPAVSTD 526
+ L+REEE+ E+ R RE+R +R+ E L E Q E
Sbjct: 546 REQLLKREEEKRLEQER-REQRLKREQEERRDQLLKREEERRQQRLKREQEE-------- 596
Query: 527 VRFANMLGQPGSTPLDLFKFYVEELKARFHDEKKIIKDILKDRGFCVEVNTAFEDFAHVI 586
R L + L+ + + LK R E++ + +LK E +
Sbjct: 597 -RLEQRLKREEVERLEQEERREQRLK-REEPEEERRQQLLKSE----EQEERRQQQLRRE 650
Query: 587 SFDKRAAALDAGNIKLTFNSLLEKAEAREREREKEEARRMRRREAAFRSMLRQAVPALEL 646
++R L + LE+ RE E E+ E + R ++ +P +
Sbjct: 651 QQERREQRLK----REEEEERLEQRLKREHEEERREQELAEEEQEQARERIKSRIPKWQW 706
Query: 647 GTAWE-EVRERFVCDSAFEQITLESERIRLFREFLQVLEQTECQHLHTKGRKHGRKGKKH 705
E + R+ V +Q E +R R +E + ++E Q + ++ ++
Sbjct: 707 QLESEADARQSKVYSRPRKQ---EGQRRRQEQEEKRRRRESELQWQEEERAHRQQQEEEQ 763
Query: 706 HHKRSHSPSGSESEEEELPPPSLRPPKRRRRNPSESGSEPSSSLDSVESGGAALGGRGSP 765
+ E E S RPP R +R E R
Sbjct: 764 RRDFTWQWQAEEKSERGRQRLSARPPLREQRERQLRAEE-----------------RQQR 806
Query: 766 SSHLLGADHGLRKAKKPKKKTKK------------RRHKSNSPESETD--PEEKAGKESD 811
L + + ++ +++ +K RR ++ + E D E++ + S
Sbjct: 807 EQRFLPEEEEKEQRRRQRREREKELQFLEEEEQLQRRERAQQLQEEEDGLQEDQERRRSQ 866
Query: 812 EKEQEQDKDRELQQAELPNRSPGFG-------IKKEKTGWDTSESELSEGELERRRR 861
E+ ++Q +L++ R + ++KE+ E EL E E+RRR
Sbjct: 867 EQRRDQKWRWQLEEERKRRRHTLYAKPALQEQLRKEQQLLQEEEEELQREEREKRRR 923
Score = 43.1 bits (100), Expect = 0.001
Identities = 53/269 (19%), Positives = 117/269 (43%), Gaps = 32/269 (11%)
Query: 230 EATQPLEQGFLQQLEEGPSSSGQHQPQQEEEESKPEPERSGLSWSNREKAKQAFKELLRD 289
E Q L++G QQL + ++E++ + E ER L + + ++ ++ +
Sbjct: 1671 EEEQLLQEGEEQQLRR--QERDRKFREEEQQLRRQERERKFLQEEQQLRRQELERKFREE 1728
Query: 290 KAVPSNASWEQAMKMVVTDPRYSAL---PKLSEKKQAFNAYKAQREKEEKEEARLRAKEA 346
+ + EQ + RY + +L +++ + +R+++ +EE +LR +
Sbjct: 1729 EQLRQETEQEQLRRQ----ERYRKILEEEQLRPEREEQQLRRQERDRKFREEEQLRQERE 1784
Query: 347 KQTLQHFLEQHERMTSTTRYRRAEQTFGELEVWAVVPE-RDRKEVYDDVLFFLAKKEKEQ 405
+Q L+ S ++R EQ E E + P+ RD K +++ L ++E ++
Sbjct: 1785 EQQLRS-------QESDRKFREEEQLRQEREEQQLRPQQRDGKYRWEEEQLQLEEQE-QR 1836
Query: 406 AKQLRRRNIQALKSILDGMSSVNFQTTWSQAQQYLMDNPSFAQDHQLQNMDKEDALICFE 465
+Q R R +A + +Q + + + ++ Q + ++E L E
Sbjct: 1837 LRQERDRQYRAEEQFA------------TQEKSRREEQELWQEEEQKRRQERERKLR--E 1882
Query: 466 EHIRALEREEEEERERARLRERRQQRKNR 494
EHIR ++EE+ R+ ++ + + R
Sbjct: 1883 EHIRRQQKEEQRHRQVGEIKSQEGKGHGR 1911
Score = 39.7 bits (91), Expect = 0.012
Identities = 62/283 (21%), Positives = 114/283 (40%), Gaps = 38/283 (13%)
Query: 243 LEEGPSSSGQHQPQQ----------EEEESKPEPERSGLSWSNRE-KAKQAFKELLRDKA 291
LEE P Q + QQ EEE+ E E L R+ K ++ ++L R +
Sbjct: 1646 LEEEPQLRRQEREQQLRHDRDRKFREEEQLLQEGEEQQLRRQERDRKFREEEQQLRRQER 1705
Query: 292 VPSNASWEQAMKMVVTDPRYSALPKLSEKKQAFNAYKAQREKEEKEEARLRAKEAKQTLQ 351
EQ ++ + ++ +L ++ + + +R ++ EE +LR + +Q L+
Sbjct: 1706 ERKFLQEEQQLRRQELERKFREEEQLRQETEQEQLRRQERYRKILEEEQLRPEREEQQLR 1765
Query: 352 HFLEQHERMTSTTRYRRAEQTFGELEVWAVVPERDRKEVYDDVLFFLAKKEKEQAKQLRR 411
R ++R EQ E E E+ + D F +E+EQ +Q R
Sbjct: 1766 -------RQERDRKFREEEQLRQERE------EQQLRSQESDRKF----REEEQLRQERE 1808
Query: 412 RNIQALKSILDGMSSVNFQTTWSQAQQYLMDNPSFAQDHQLQNMDKEDALICFEEHIRAL 471
Q DG + W + Q L + + + + E+ +E R
Sbjct: 1809 EQ-QLRPQQRDG------KYRWEEEQLQLEEQEQRLRQERDRQYRAEEQFAT-QEKSRRE 1860
Query: 472 ERE--EEEERERARLRERRQQRKNREAFQTFLDELHETGQLHS 512
E+E +EEE++R + RER+ + ++ Q + G++ S
Sbjct: 1861 EQELWQEEEQKRRQERERKLREEHIRRQQKEEQRHRQVGEIKS 1903
Score = 38.5 bits (88), Expect = 0.027
Identities = 61/276 (22%), Positives = 110/276 (39%), Gaps = 36/276 (13%)
Query: 609 EKAEAREREREKEEARRMRRREAAFRSMLRQAVPALELGTAWEEVRERFVCDSAFEQITL 668
EK +ERER+ E +++ E R+ EL + + E EQ+
Sbjct: 1039 EKRRLQERERQYREEEELQQEEEQLLGEERETRRRQELERQYRKEEE---LQQEEEQLLR 1095
Query: 669 E-------SERIRLFREFLQVLEQTECQHLHTKGRKHGRKGKKHHHKRSHSPSGSESEEE 721
E ER R RE + L+Q E Q L + K R+ + ++ + EEE
Sbjct: 1096 EEPEKRRRQERERQCRE-EEELQQEEEQLLREEREKRRRQELERQYREEEE---VQQEEE 1151
Query: 722 ELPPPSLRPPKRRRRNPSESGSEPSSSLDSVESGGAALGGRGSPSSHLLGADHGLRKAKK 781
+L P++RRR E L E R + R+ ++
Sbjct: 1152 QL---LREEPEKRRRQELERQYREEEELQQEEEQLL----REEQEKRRQERERQYREEEE 1204
Query: 782 PKKKTKKRRHKSNSPESET----DPEEKAGKESDE---KEQEQDKDRELQQAELPNRSPG 834
+++ +K+R++ S+ +PE++ ++ K +E ++ R+L+ ++L +R
Sbjct: 1205 LQRQKRKQRYRDEDQRSDLKWQWEPEKENAVRDNKVYCKGRENEQFRQLEDSQLRDRQ-- 1262
Query: 835 FGIKKEKTGWDTSESELSEGELERRRRTLLQQLDDH 870
++ E + + E ERRR QQ D H
Sbjct: 1263 ---SQQDLQHLLGEQQERDREQERRR---WQQRDRH 1292
Score = 36.2 bits (82), Expect = 0.14
Identities = 52/291 (17%), Positives = 121/291 (41%), Gaps = 19/291 (6%)
Query: 233 QPLEQGFLQQLEEGPSSSGQHQPQQEEEESKPEPERSGLSWSNREKAKQAF-KELLRDKA 291
Q E+ F++ ++ GQ Q +QE + E E+ ++ +Q ++ L ++
Sbjct: 1591 QEQERKFMEDEQQLRRQEGQQQLRQERDRKFREDEQLLQEREEQQLHRQERDRKFLEEEP 1650
Query: 292 VPSNASWEQAMKMVVTDPRYSALPKLSEKKQAFNAYKAQREKE-EKEEARLRAKEAKQTL 350
EQ ++ D ++ +L ++ + + +R+++ +EE +LR +E ++
Sbjct: 1651 QLRRQEREQQLRHD-RDRKFREEEQLLQEGEEQQLRRQERDRKFREEEQQLRRQERERKF 1709
Query: 351 QHFLEQHERMTSTTRYRRAEQTFGELEVWAVVPERDRKEVYDDVLFFLAKKEKEQAKQLR 410
+Q R ++R EQ E E + + +++ ++ ++E++ +Q R
Sbjct: 1710 LQEEQQLRRQELERKFREEEQLRQETEQEQLRRQERYRKILEEEQLRPEREEQQLRRQER 1769
Query: 411 RRNIQALKSILDGMSSVNFQTTWSQAQQYLMDNPSFAQDH---QLQNMDKEDALICFEEH 467
R + + + ++ ++ + + Q+ QL+ ++ EE
Sbjct: 1770 DRKFREEEQLRQEREEQQLRS--QESDRKFREEEQLRQEREEQQLRPQQRDGKYRWEEEQ 1827
Query: 468 IRALEREEEEERERARLRERRQQRKNREAFQTFLDELHETGQLHSMSTWME 518
++ EE+E+R R +ER +Q + E F T E + W E
Sbjct: 1828 LQL---EEQEQRLR---QERDRQYRAEEQFAT-----QEKSRREEQELWQE 1867
>gi|55741709 RNA binding motif protein 25 [Homo sapiens]
Length = 843
Score = 71.6 bits (174), Expect = 3e-12
Identities = 181/840 (21%), Positives = 308/840 (36%), Gaps = 163/840 (19%)
Query: 19 MGLPPMSQRPP-AIPPMPPGILPPMLPPMGAPPPLTQIPGMVPPMMPGMLMPAVPVTAAT 77
M PP RPP IP +PPGI PP P G PPP+ PG PM+P + P
Sbjct: 1 MSFPPHLNRPPMGIPALPPGIPPPQFP--GFPPPVP--PGT--PMIPVPMSIMAPAPTVL 54
Query: 78 APGADTASSAVAGTGPPRALWS----EHVAPDGRIYYYNADDKQSVWEKPSVLKSKAELL 133
P + L + E+ P ++ N +K S +L +K L+
Sbjct: 55 VPTVSMVGKHLGARKDHPGLKAKENDENCGPTTTVFVGNISEKASDMLIRQLL-AKCGLV 113
Query: 134 LSQCPWKEYKSDTGKPYYYN---NQSKESRWTRPKDLDDLEV-----LVKQEAAGKQQQQ 185
LS WK + +GK + + ES + L DL++ LVK +A K + Q
Sbjct: 114 LS---WKRVQGASGKLQAFGFCEYKEPESTLRALRLLHDLQIGEKKLLVKVDA--KTKAQ 168
Query: 186 LPQTLQPQPPQPQPDPPPVPPGPTPVPTGLLEPEPGGSEDCDVL-EATQPLEQGFLQQLE 244
L + + G PE ++D + L E T+ +Q +E
Sbjct: 169 LDEWKAKKKAS----------------NGNARPETVTNDDEEALDEETKRRDQMIKGAIE 212
Query: 245 E--GPSSSGQHQPQQEEEESKPEPERSGLSWSNREKAKQAFKELLRDKAVPSNASWEQAM 302
SS + P QE + S P ++ +EK + F+ +P ++ +
Sbjct: 213 VLIREYSSELNAPSQESD-SHPRKKK-------KEKKEDIFRRFPVAPLIPYPLITKEDI 264
Query: 303 KMVVT--DPRYSALPKLSEKKQAFNAYKAQREKEEKEEARLRAKEAKQTLQHFLEQHERM 360
+ D R ++S+ + + ++ K+EKE + + ++ + E+ R
Sbjct: 265 NAIEMEEDKRDLISREISKFRDTHKKLEEEKGKKEKERQEIEKERRERERERERERERRE 324
Query: 361 TSTTRYRRAEQTFGELEVWAVVPERDRKEVYDDVLFFLAKKEKEQAKQLRRRNIQALKSI 420
R R E+ E E ER+R+ D +++++ K+ R +
Sbjct: 325 RERERERERER---EKE-----KERERERERD--------RDRDRTKERDRDRDRERDRD 368
Query: 421 LDGMSSVNFQTTWSQAQQYLMDNPSFAQDHQLQNMDKEDALICFEEHIRALEREEEEERE 480
D S + S++++ D + ++E E R ERE E ERE
Sbjct: 369 RDRERSSDRNKDRSRSREKSRD----------RERERE------RERERERERERERERE 412
Query: 481 RARLRERRQQRKNREAFQTFLDELHETG--QLHSMSTWMELYPAVSTDVRFANMLGQPGS 538
R R RER ++R+ + + +E E + E A ++ + + +
Sbjct: 413 REREREREREREREKDKKRDREEDEEDAYERRKLERKLREKEAAYQERLKNWEIRERKKT 472
Query: 539 TPLDLFKFYVEELKARFHDEKKIIKDILKDRGFCVEVNTAFEDFAHVISFDKRAAALDAG 598
+ EE + E K +K+ L+D ++D D
Sbjct: 473 REYEKEAEREEERRREMAKEAKRLKEFLED----------YDD--------------DRD 508
Query: 599 NIKLTFNSLLEKAEAREREREKEEARRMRRREAAFRSMLRQAVPALELGTAWEEVRERFV 658
+ K S L+K R+RE+E E R R+RE EL EE+R+R +
Sbjct: 509 DPKYYRGSALQK-RLRDREKEMEADERDRKREKE------------EL----EEIRQRLL 551
Query: 659 C------DSAFEQITLESERIRLFREFLQVLEQTECQHLHTKGRKHGRKGKKHHHKRSHS 712
D+ +++ E+ER R Q+ ++ E + + K+ ++
Sbjct: 552 AEGHPDPDAELQRMEQEAER----RRQPQIKQEPESE--------EEEEEKQEKEEKREE 599
Query: 713 PSGSESEEEELP--PPSLRPPKRRRRNPSESGSEPSSSLDSVESGGAALGGRGSPSSHLL 770
P E E E+ P P+LRP S SG+ ++ G + SP
Sbjct: 600 PMEEEEEPEQKPCLKPTLRPISSAPSVSSASGNATPNTPGDESPCGIIIPHENSP----- 654
Query: 771 GADHGLRKAKKPKKKTKKRRHKSNSPESETDPEEKA-------GKESDEKEQEQDKDREL 823
D + +PK + SNSP + K K DE + + R+L
Sbjct: 655 --DQQQPEEHRPKIGLSLKLGASNSPGQPNSVKRKKLPVDSVFNKFEDEDSDDVPRKRKL 712
Score = 39.7 bits (91), Expect = 0.012
Identities = 49/239 (20%), Positives = 94/239 (39%), Gaps = 67/239 (28%)
Query: 609 EKAEAREREREKEEA-------RRMRRREAAFRSMLRQAVPALELGTAWEEVRERFVCDS 661
EK + R+RE ++E+A R++R +EAA++ L+ WE +RER
Sbjct: 426 EKDKKRDREEDEEDAYERRKLERKLREKEAAYQERLKN----------WE-IRERKKTRE 474
Query: 662 AFEQITLESERIR-------LFREFLQVLEQTECQHLHTKGRKHGRKGKKHHHKRSHSPS 714
++ E ER R +EFL+ + + +G ++ + +
Sbjct: 475 YEKEAEREEERRREMAKEAKRLKEFLEDYDDDRDDPKYYRGSALQKRLRDREKEMEADER 534
Query: 715 GSESEEEELPPPSLRPPKRRRRNPSESGSEPSSSLDSVESGGAALGGRGSPSSHLLGADH 774
+ E+EEL + R+R +E +P + L +E
Sbjct: 535 DRKREKEELE-------EIRQRLLAEGHPDPDAELQRME--------------------- 566
Query: 775 GLRKAKKPKKKTKKRRHKSNSPESETDPEEKAGKESDEKEQEQDKDRELQQAELPNRSP 833
++ ++RR E E++ EE+ +E +EK +E +++ E P + P
Sbjct: 567 ---------QEAERRRQPQIKQEPESEEEEEEKQEKEEKREE-----PMEEEEEPEQKP 611
Score = 33.1 bits (74), Expect = 1.1
Identities = 14/49 (28%), Positives = 30/49 (61%)
Query: 777 RKAKKPKKKTKKRRHKSNSPESETDPEEKAGKESDEKEQEQDKDRELQQ 825
+K K+ ++ K+RR + E E + E+ + E+E+E++K+RE ++
Sbjct: 297 KKEKERQEIEKERRERERERERERERREREREREREREREKEKERERER 345
Score = 32.3 bits (72), Expect = 2.0
Identities = 34/168 (20%), Positives = 58/168 (34%), Gaps = 2/168 (1%)
Query: 701 KGKKHHHKRSHSPSGSESEEEELPPPSLRPPKRRRRNPSESGSEPSSSLDSVESGGA-AL 759
KGKK ++ E E E R +R R E E +
Sbjct: 295 KGKKEKERQEIEKERRERERERERERERREREREREREREREKEKERERERERDRDRDRT 354
Query: 760 GGRGSPSSHLLGADHGLRKAKKPKKKTKKRRHKSNSPESETDPEEKAGKESDEKEQEQDK 819
R D ++ K + R KS E E + E + +E E+E+E+++
Sbjct: 355 KERDRDRDRERDRDRDRERSSDRNKDRSRSREKSRDRERERERERERERER-ERERERER 413
Query: 820 DRELQQAELPNRSPGFGIKKEKTGWDTSESELSEGELERRRRTLLQQL 867
+RE ++ R +E+ D E E +L + ++L
Sbjct: 414 EREREREREREREKDKKRDREEDEEDAYERRKLERKLREKEAAYQERL 461
Score = 32.3 bits (72), Expect = 2.0
Identities = 51/264 (19%), Positives = 103/264 (39%), Gaps = 16/264 (6%)
Query: 609 EKAEAREREREKEEARRMRRREAAFRSMLRQAVPALELGTAWEEVRERFVCDSAFEQITL 668
E+ REREREKE+ R R R ++ + + RER + +
Sbjct: 326 EREREREREREKEKERERERERDRDRDRTKERDRDRDRERDRDRDRERSSDRNKDRSRSR 385
Query: 669 ESERIRLFREFLQVLEQTECQHLHTKGRKHGRKGKKHHHKRSHSPSGSESEEEELPPPSL 728
E R R RE + E+ E + + R+ R+ ++ + + EE+E
Sbjct: 386 EKSRDR-ERERERERER-EREREREREREREREREREREREREKDKKRDREEDEEDAYER 443
Query: 729 RPPKRRRRNPSESGSEPSSSLDSVESGGAALGGRGSPSSHLLGADHGLRKAKKPKKKTKK 788
R +R+ R + E + + E R + A+ + ++ K+ K+
Sbjct: 444 RKLERKLREKEAAYQERLKNWEIRE--------RKKTREYEKEAEREEERRREMAKEAKR 495
Query: 789 -RRHKSNSPESETDPEEKAGKESDEKEQEQDKDRELQQAELPNRSPGFGIKKEK---TGW 844
+ + + DP+ G ++ ++++K+ E + + +++ G
Sbjct: 496 LKEFLEDYDDDRDDPKYYRGSALQKRLRDREKEMEADERDRKREKEELEEIRQRLLAEGH 555
Query: 845 DTSESELS--EGELERRRRTLLQQ 866
++EL E E ERRR+ ++Q
Sbjct: 556 PDPDAELQRMEQEAERRRQPQIKQ 579
Score = 31.2 bits (69), Expect = 4.4
Identities = 13/49 (26%), Positives = 29/49 (59%)
Query: 777 RKAKKPKKKTKKRRHKSNSPESETDPEEKAGKESDEKEQEQDKDRELQQ 825
+K ++ K K +K R + E + E + +E E+E+E++++RE ++
Sbjct: 289 KKLEEEKGKKEKERQEIEKERRERERERERERERREREREREREREREK 337
>gi|224451135 splicing factor, arginine/serine-rich 15 isoform 3
[Homo sapiens]
Length = 1125
Score = 68.6 bits (166), Expect = 2e-11
Identities = 81/303 (26%), Positives = 109/303 (35%), Gaps = 81/303 (26%)
Query: 1 MMPPPFMPPPGIPPPFPPMGLPPMSQRPPAIPP------MPPGILPPMLPPMGAPPPLTQ 54
+ PP F PP GIPPP G+PP PP + P +PPG LPP G PPP+T
Sbjct: 695 LQPPAFTPPLGIPPPGFGPGVPPPPPPPPFLRPGFNPMHLPPGFLPP-----GPPPPITP 749
Query: 55 IPGMVPPMMPGMLMPAVPVTA---------------ATAPGADTASSAVAGTGPPRALWS 99
+ PP P + +P + A A P A T T P L +
Sbjct: 750 PVSIPPPHTPPISIPNLVSGARGNAESGDSVKMYGSAVPPAAPTNLPTPPVTQPVSLLGT 809
Query: 100 EHVAPDGRIYYYNADDKQSVWEKPSVLKSKAELLLSQCPWKEYKSDTGKPYYYNNQSKES 159
+ VAP G + A + +P ++ L + P G P
Sbjct: 810 QGVAP-GPVIGLQAPSTGLLGARPGLIP------LQRPP--------GMP---------- 844
Query: 160 RWTRPKDLDDLEVLVKQEAAGKQQQQLPQTLQPQPPQPQPD----PPP-------VPPGP 208
P L ++ + +P + + P P P PPP P GP
Sbjct: 845 ----PPHLQRFPLM--------PPRPMPPHMMHRGPPPGPGGFAMPPPHGMKGPFPPHGP 892
Query: 209 TPVPTGL-----LEPEPGGSEDCDVLEATQPLEQGFLQQLEEGPSSSGQHQPQQEEEESK 263
P G+ P PGG ED D + QP +Q Q + P Q Q QQ +
Sbjct: 893 FVRPGGMPGLGGPGPGPGGPEDRDGRQ--QPPQQPQQQPQPQAPQQPQQQQQQQPPPSQQ 950
Query: 264 PEP 266
P P
Sbjct: 951 PPP 953
Score = 38.1 bits (87), Expect = 0.036
Identities = 45/217 (20%), Positives = 89/217 (41%), Gaps = 8/217 (3%)
Query: 176 QEAAGKQQQQLPQTLQPQPPQPQPDPP----PVPPGPTPVPTGLLEPEPGGSEDCDVLEA 231
Q+ A Q Q + Q QP+ Q DP P+PP GLL P V+
Sbjct: 328 QQPAYTQHQNMDQ-FQPRMMGIQQDPMHHQVPLPPNGQMPGFGLLPTPPFPPMAQPVIPP 386
Query: 232 TQPLEQGFLQ--QLEEGPSSSGQHQPQQEEEESKPEPERSGLSWSNREKAKQAFKELLRD 289
T P++Q F Q + P + HQ + E E+ + + +S + + +++ A + R
Sbjct: 387 TPPVQQPFQASFQAQNEPLTQKPHQQEMEVEQPCIQEVKRHMSDNRKSRSRSASRSPKRR 446
Query: 290 KAVPSNASWEQAMKMVVTDPRYSALPKLSEKKQAFNAYKAQREKEEKEEARLRAKEAKQ- 348
++ + S + + R + Q + +RE+ +K +++ + A
Sbjct: 447 RSRSGSRSRRSRHRRSRSRSRDRRRHSPRSRSQERRDREKERERRQKGLPQVKPETASVC 506
Query: 349 TLQHFLEQHERMTSTTRYRRAEQTFGELEVWAVVPER 385
+ ++ Q ++ T+ + FG +E ++P R
Sbjct: 507 STTLWVGQLDKRTTQQDVASLLEEFGPIESINMIPPR 543
Score = 35.4 bits (80), Expect = 0.23
Identities = 23/60 (38%), Positives = 27/60 (45%), Gaps = 7/60 (11%)
Query: 36 PGILPPMLPPMGAPPPLTQIPGMVPPMMPGMLMPAVPVTAATAPGADTASSAV--AGTGP 93
P LP +PP+ P P+T P VPP PG PV A P A T + G GP
Sbjct: 659 PKPLPVPVPPIPVPAPITVPPPQVPPHQPGP-----PVVGALQPPAFTPPLGIPPPGFGP 713
Score = 35.0 bits (79), Expect = 0.30
Identities = 26/117 (22%), Positives = 54/117 (46%), Gaps = 10/117 (8%)
Query: 712 SPSGSESEEEELPPPSLRPPKRRRRNP---SESGSEPSSSLDSVESGGAALGGRGSPSSH 768
+P + ++++ PPPS +PP +++ +++ + +S D G + G R
Sbjct: 933 APQQPQQQQQQQPPPSQQPPPTQQQPQQFRNDNRQQFNSGRDQERFGRRSFGNRVENDRE 992
Query: 769 LLGADHGLRKAKKPKKKTKKRRHKSNSPESE--TDPEEKAGKESDEKEQEQD-KDRE 822
+G R + +R SP+ + D EE+ + S +++E+D +DRE
Sbjct: 993 ----RYGNRNDDRDNSNRDRREWGRRSPDRDRHRDLEERNRRSSGHRDRERDSRDRE 1045
Score = 33.1 bits (74), Expect = 1.1
Identities = 22/53 (41%), Positives = 24/53 (45%), Gaps = 5/53 (9%)
Query: 7 MPPPGIPPPF---PPMGLPPMSQRPPAIPPMPPGILPPMLPPMGAPPPLTQIP 56
+PP G P F P PPM+Q P IPP PP P PLTQ P
Sbjct: 359 LPPNGQMPGFGLLPTPPFPPMAQ--PVIPPTPPVQQPFQASFQAQNEPLTQKP 409
Score = 33.1 bits (74), Expect = 1.1
Identities = 18/45 (40%), Positives = 23/45 (51%), Gaps = 1/45 (2%)
Query: 191 QPQPPQPQPDPPPVPPGPTPVPTGLLEPE-PGGSEDCDVLEATQP 234
+P P P+P P PVPP P P P + P+ P V+ A QP
Sbjct: 653 EPVSPIPKPLPVPVPPIPVPAPITVPPPQVPPHQPGPPVVGALQP 697
Score = 32.7 bits (73), Expect = 1.5
Identities = 14/33 (42%), Positives = 17/33 (51%)
Query: 188 QTLQPQPPQPQPDPPPVPPGPTPVPTGLLEPEP 220
+T +P P P P PVP P PVP + P P
Sbjct: 648 ETSHTEPVSPIPKPLPVPVPPIPVPAPITVPPP 680
Score = 32.0 bits (71), Expect = 2.6
Identities = 21/63 (33%), Positives = 26/63 (41%), Gaps = 5/63 (7%)
Query: 15 PFPPMGLPPMSQRPPAIPPMPPGILPPMLPPMGAPPPLT---QIPGMVPPM--MPGMLMP 69
P P+ P PP P P + PP +PP PP+ Q P PP+ P P
Sbjct: 654 PVSPIPKPLPVPVPPIPVPAPITVPPPQVPPHQPGPPVVGALQPPAFTPPLGIPPPGFGP 713
Query: 70 AVP 72
VP
Sbjct: 714 GVP 716
Score = 31.2 bits (69), Expect = 4.4
Identities = 16/33 (48%), Positives = 17/33 (51%), Gaps = 1/33 (3%)
Query: 181 KQQQQLPQTLQPQPPQPQPDPPPVPPGPTPVPT 213
+Q QQ PQ PQ PQ Q P PP P PT
Sbjct: 923 QQPQQQPQPQAPQQPQQQQQQQP-PPSQQPPPT 954
Score = 30.4 bits (67), Expect = 7.4
Identities = 20/70 (28%), Positives = 34/70 (48%), Gaps = 1/70 (1%)
Query: 469 RALEREEEEERERARLRERRQQRKNREAFQTFLDELH-ETGQLHSMSTWMELYPAVSTDV 527
R+ R+ R+R +ERR + K RE Q L ++ ET + S + W+ +T
Sbjct: 463 RSRSRDRRRHSPRSRSQERRDREKERERRQKGLPQVKPETASVCSTTLWVGQLDKRTTQQ 522
Query: 528 RFANMLGQPG 537
A++L + G
Sbjct: 523 DVASLLEEFG 532
Score = 30.0 bits (66), Expect = 9.7
Identities = 22/74 (29%), Positives = 27/74 (36%), Gaps = 12/74 (16%)
Query: 13 PPPFPPMGLPPMSQRPPA---------IPPMPPGILPPMLPPMGAPPPLTQIPG---MVP 60
PPP P G P + PA P GI + PP Q+PG +
Sbjct: 314 PPPQAPFGFPGDGMQQPAYTQHQNMDQFQPRMMGIQQDPMHHQVPLPPNGQMPGFGLLPT 373
Query: 61 PMMPGMLMPAVPVT 74
P P M P +P T
Sbjct: 374 PPFPPMAQPVIPPT 387
>gi|148727264 transcription elongation regulator 1-like [Homo
sapiens]
Length = 586
Score = 68.2 bits (165), Expect = 3e-11
Identities = 78/370 (21%), Positives = 152/370 (41%), Gaps = 60/370 (16%)
Query: 56 PGMVPPMMPGMLMPAVPVTAATAPGADTASSAVAGTGPPRALWSEHVAPDGRIYYYNADD 115
P V P L P + + T+P +DT + PP + + DG + +D
Sbjct: 261 PSSVQPRHFLTLAP-IKIPLRTSPVSDTRTERGRVARPPALMLRAQKSRDG-----DKED 314
Query: 116 KQSVWEKPSVL-----------KSKAELLLSQCPWKEYKSDTGKPYYYNNQSKESRWTRP 164
K E P +L + A + PW + + +++N S W +P
Sbjct: 315 K----EPPPMLGGGEDSTARGNRPVASTPVPGSPWCVVWTGDDRVFFFNPTMHLSVWEKP 370
Query: 165 KDLDDLEVL--VKQEAAGKQQQQLPQTLQPQPPQPQPDPPPVPPGPTPVPTGLLEPEPGG 222
DL D L + ++ K++ + P T + +
Sbjct: 371 MDLKDRGDLNRIIEDPPHKRKLEAPATDNSDGSSSEDN---------------------- 408
Query: 223 SEDCDVLEATQPLEQGFLQQLEEGPSSSGQHQPQQEEEESKPEPERSGLSWSNREKAKQA 282
ED DV + EG S + ++E++ ++ P + L R
Sbjct: 409 REDQDVKTK---------RNRTEGCGSPKPEEAKREDKGTRTPPPQILLPLEERVTH--- 456
Query: 283 FKELLRDKAVPSNASWEQAMKMVVTDPRYSALPKLSEKKQAFNAYKAQREKEEKEEARLR 342
F+++L ++ V + ++WE+ + +V DPRY L E+KQ F + R KEE +E + +
Sbjct: 457 FRDMLLERGVSAFSTWEKELHKIVFDPRYLLLNS-EERKQIFEQFVKTRIKEEYKEKKSK 515
Query: 343 AKEAKQTLQHFLEQHERMTSTTRYRRAEQTFGELEVWAVVPER-DRKEVYDDVLFFLAKK 401
AK+ + LE+ +++ T ++ + +G + + +V +R D++ ++ + L K+
Sbjct: 516 LLLAKEEFKKLLEE-SKVSPRTTFKEFAEKYGRDQRFRLVQKRKDQEHFFNQFILILKKR 574
Query: 402 EKEQAKQLRR 411
+KE +LR+
Sbjct: 575 DKENRLRLRK 584
Score = 38.5 bits (88), Expect = 0.027
Identities = 50/222 (22%), Positives = 76/222 (34%), Gaps = 52/222 (23%)
Query: 23 PMSQRPPAIPP---MPPG-----------ILPPMLPPMGAPPPLTQIPGMVPPMMPGMLM 68
PM PP PP M PG ++PP+L PP +PG +PG
Sbjct: 28 PMDAEPPPPPPWVWMVPGSAGLLRLSAGVVVPPVLLASAPPPAAPLLPG-----LPGWPA 82
Query: 69 PAVPVTAATAPGADTASSAVAGTGPPRALWSEHVAPDGRIYYYNADDKQSVWEKPSVLKS 128
P+ PV + S+A A P AL + + S+ PS
Sbjct: 83 PSEPVLPLLPLPSAPDSAAAAAAHPFPALHGQ---------WLFGGHSPSLGLPPSSTVE 133
Query: 129 KAELLLSQCP----------WKEYKSDTGKPYYYNNQSKESRWTRPKDLDDLEVLVKQEA 178
+ CP W + + K ++ N+ + +S W P +E+
Sbjct: 134 LVPVFPHLCPSALATPIGKSWIDKRIPNCKIFFNNSFALDSTWIHP-----------EES 182
Query: 179 AGKQQQQLPQTLQPQPPQPQPDPPPVPPGPTPVPTGLLEPEP 220
+ P+ L Q P P P+PT +L P+P
Sbjct: 183 RFFHGHEKPRLLANQVAVSLSRP---APASRPLPTVVLAPQP 221
>gi|7706501 WW domain binding protein 11 [Homo sapiens]
Length = 641
Score = 67.0 bits (162), Expect = 7e-11
Identities = 53/152 (34%), Positives = 63/152 (41%), Gaps = 38/152 (25%)
Query: 4 PPFMPPPGIP----------PPFPPMGLPPMSQRPPAIPPMPPGILPPMLPPMGAPPPL- 52
PPF+ PPG+P PP PP G RPP PP PP LPP PP G PP L
Sbjct: 439 PPFLRPPGMPGLRGPLPRLLPPGPPPG------RPPGPPPGPPPGLPPGPPPRGPPPRLP 492
Query: 53 TQIPGMVPPMMPGMLMPAVPVTAATAPGADTASSAVAGTGPPRALWSEHV--APDGRIYY 110
P +PP PGM+ P + AP G PP L + V AP I
Sbjct: 493 PPAPPGIPPPRPGMMRPPLVPPLGPAP---------PGLFPPAPLPNPGVLSAPPNLIQR 543
Query: 111 YNADDKQ----------SVWEKPSVLKSKAEL 132
ADD ++ KP + KAE+
Sbjct: 544 PKADDTSAATIEKKATATISAKPQITNPKAEI 575
Score = 53.1 bits (126), Expect = 1e-06
Identities = 41/103 (39%), Positives = 43/103 (41%), Gaps = 19/103 (18%)
Query: 3 PPPFMPPPGIP--PPFPPMGLPPMSQRPPAIPPM--PPGI------LPPMLPPMGAPPPL 52
PPP PPP P PP PP GLPP PP PP PPG+ LP +LPP PPP
Sbjct: 410 PPPLGPPPAPPLRPPGPPTGLPPGP--PPGAPPFLRPPGMPGLRGPLPRLLPP--GPPP- 464
Query: 53 TQIPGMVPPMMPGMLMPAVPVTAATAPGADTASSAVAGTGPPR 95
G P PG P P A G PPR
Sbjct: 465 ----GRPPGPPPGPPPGLPPGPPPRGPPPRLPPPAPPGIPPPR 503
Score = 51.6 bits (122), Expect = 3e-06
Identities = 40/100 (40%), Positives = 45/100 (45%), Gaps = 19/100 (19%)
Query: 3 PPPFMPP-----PGIPPPFPPMGLPPMSQRPPAIPPMPPGILPPMLPPMGAPPPLTQIPG 57
PP +PP P +P P PP+G PP PP PP PP LPP PP GAPP L
Sbjct: 393 PPQSVPPSQIQAPPMPGP-PPLGPPPA---PPLRPPGPPTGLPPG-PPPGAPPFLR---- 443
Query: 58 MVPPMMPGMLMPAVPVTAATAPGADTASSAVAGTGPPRAL 97
PP MPG+ P+ PG GPP L
Sbjct: 444 --PPGMPGL---RGPLPRLLPPGPPPGRPPGPPPGPPPGL 478
Score = 45.8 bits (107), Expect = 2e-04
Identities = 33/93 (35%), Positives = 40/93 (43%), Gaps = 15/93 (16%)
Query: 3 PPPFMPPPGIPPPFPPMGLPPMSQRPPAIPP-MPPGILPPMLPPMGAPPPLTQIPGMVPP 61
PP PPP PPP PP+ RPP P +PPG PP PP PP + + G +P
Sbjct: 405 PPMPGPPPLGPPPAPPL-------RPPGPPTGLPPGP-PPGAPPFLRPPGMPGLRGPLPR 456
Query: 62 MMPGMLMPAVPVTAATAPGADTASSAVAGTGPP 94
++P P P PG GPP
Sbjct: 457 LLPPGPPPGRP------PGPPPGPPPGLPPGPP 483
Score = 36.2 bits (82), Expect = 0.14
Identities = 21/52 (40%), Positives = 25/52 (48%), Gaps = 16/52 (30%)
Query: 186 LPQTLQP-----QPPQPQPDPPP-VPPG----------PTPVPTGLLEPEPG 221
LP+ L P +PP P P PPP +PPG P P P G+ P PG
Sbjct: 454 LPRLLPPGPPPGRPPGPPPGPPPGLPPGPPPRGPPPRLPPPAPPGIPPPRPG 505
Score = 35.4 bits (80), Expect = 0.23
Identities = 62/285 (21%), Positives = 96/285 (33%), Gaps = 65/285 (22%)
Query: 2 MPPPFMPPPGI-------PPPFPPMGLPPMSQRPPAIPPMPPGILPPMLPPMGAPPPLTQ 54
+P P PP I PP + + P+ +P +PPG PP PP PP + Q
Sbjct: 156 IPLPGAQPPSILKKTSAYGPPTRAVSILPLLGH--GVPRLPPGRKPPGPPPGPPPPQVVQ 213
Query: 55 IPGM-------VPPMMPGMLMPAVPVTAATAPGADTASSAVAGTGPPRALWSEH------ 101
+ G +PP M P A D +S++ P +H
Sbjct: 214 MYGRKVGFALDLPPRRRDEDMLYSPELAQRGHDDDVSSTSEDDGYPEDMDQDKHDDSTDD 273
Query: 102 -------VAPDGRIYYY-------NADDKQS-----VWEKPSVLKSKAELLLSQCPWKEY 142
DG + + N ++K+S + P + K + + P +
Sbjct: 274 SDTDKSDGESDGDEFVHRDNGERDNNEEKKSGLSVRFADMPGKSRKKKKNMKELTPLQAM 333
Query: 143 KSDTGKPYYYNNQSKESRWTRPKDLDDLEVLVKQEAAGKQ----------------QQQL 186
+ ++ D DD + ++ + KQ QQ
Sbjct: 334 MLRMAGQEIPEEGREVEEFSEDDDEDDSDDSEAEKQSQKQHKEESHSDGTSTASSQQQAP 393
Query: 187 PQTLQPQPPQ--PQPDPPPVPPGPTP------VPTGLLEPEPGGS 223
PQ++ P Q P P PPP+ P P P PTGL P G+
Sbjct: 394 PQSVPPSQIQAPPMPGPPPLGPPPAPPLRPPGPPTGLPPGPPPGA 438
Score = 31.6 bits (70), Expect = 3.3
Identities = 17/41 (41%), Positives = 21/41 (51%), Gaps = 7/41 (17%)
Query: 1 MMPPPFMPPPGIPPP--FPPMGLPPMSQRPPAIPPMPPGIL 39
MM PP +PP G PP FPP LP P + PP ++
Sbjct: 506 MMRPPLVPPLGPAPPGLFPPAPLP-----NPGVLSAPPNLI 541
Score = 31.2 bits (69), Expect = 4.4
Identities = 15/35 (42%), Positives = 17/35 (48%), Gaps = 3/35 (8%)
Query: 187 PQTLQPQPPQPQPDP---PPVPPGPTPVPTGLLEP 218
P L P PP P P PP PPG P G++ P
Sbjct: 475 PPGLPPGPPPRGPPPRLPPPAPPGIPPPRPGMMRP 509
>gi|224451133 splicing factor, arginine/serine-rich 15 isoform 2
[Homo sapiens]
Length = 1132
Score = 65.9 bits (159), Expect = 2e-10
Identities = 82/307 (26%), Positives = 104/307 (33%), Gaps = 67/307 (21%)
Query: 1 MMPPPFMPPPGIPPPFPPMGLPPMSQRPPAIPP------MPPGILPPMLPPMGAPPPLTQ 54
+ PP F PP GIPPP G+PP PP + P +PPG LPP G PPP+T
Sbjct: 680 LQPPAFTPPLGIPPPGFGPGVPPPPPPPPFLRPGFNPMHLPPGFLPP-----GPPPPITP 734
Query: 55 IPGMVPPMMPGMLMPAVPVTAATAPGADTASSAVAGTGPPRALWSEHVAPDGRIYYYNAD 114
+ PP P + ++P + DT G P + NA+
Sbjct: 735 PVSIPPPHTPPI---SIPNSTIAGINEDTTKDLSIGNPIPTVVSGAR---------GNAE 782
Query: 115 DKQSVWEKPSVLKSKAELLLSQCPWKEYKS-------DTGKPYYYNNQSKESRWTRPKDL 167
SV S + A L P + S G S RP
Sbjct: 783 SGDSVKMYGSAVPPAAPTNLPTPPVTQPVSLLGTQGVAPGPVIGLQAPSTGLLGARP--- 839
Query: 168 DDLEVLVKQEAAGKQQQQLPQTLQPQPPQPQP------DPPPVPPG-PTPVPTGLL---- 216
++ Q G L Q PP+P P PPP P G P P G+
Sbjct: 840 ---GLIPLQRPPGMPPPHL-QRFPLMPPRPMPPHMMHRGPPPGPGGFAMPPPHGMKGPFP 895
Query: 217 -----------------EPEPGGSEDCDVLEATQPLEQGFLQQLEEGPSSSGQHQPQQEE 259
P PGG ED D + QP +Q Q + P Q Q QQ
Sbjct: 896 PHGPFVRPGGMPGLGGPGPGPGGPEDRDGRQ--QPPQQPQQQPQPQAPQQPQQQQQQQPP 953
Query: 260 EESKPEP 266
+P P
Sbjct: 954 PSQQPPP 960
Score = 38.1 bits (87), Expect = 0.036
Identities = 45/217 (20%), Positives = 89/217 (41%), Gaps = 8/217 (3%)
Query: 176 QEAAGKQQQQLPQTLQPQPPQPQPDPP----PVPPGPTPVPTGLLEPEPGGSEDCDVLEA 231
Q+ A Q Q + Q QP+ Q DP P+PP GLL P V+
Sbjct: 313 QQPAYTQHQNMDQ-FQPRMMGIQQDPMHHQVPLPPNGQMPGFGLLPTPPFPPMAQPVIPP 371
Query: 232 TQPLEQGFLQ--QLEEGPSSSGQHQPQQEEEESKPEPERSGLSWSNREKAKQAFKELLRD 289
T P++Q F Q + P + HQ + E E+ + + +S + + +++ A + R
Sbjct: 372 TPPVQQPFQASFQAQNEPLTQKPHQQEMEVEQPCIQEVKRHMSDNRKSRSRSASRSPKRR 431
Query: 290 KAVPSNASWEQAMKMVVTDPRYSALPKLSEKKQAFNAYKAQREKEEKEEARLRAKEAKQ- 348
++ + S + + R + Q + +RE+ +K +++ + A
Sbjct: 432 RSRSGSRSRRSRHRRSRSRSRDRRRHSPRSRSQERRDREKERERRQKGLPQVKPETASVC 491
Query: 349 TLQHFLEQHERMTSTTRYRRAEQTFGELEVWAVVPER 385
+ ++ Q ++ T+ + FG +E ++P R
Sbjct: 492 STTLWVGQLDKRTTQQDVASLLEEFGPIESINMIPPR 528
Score = 35.4 bits (80), Expect = 0.23
Identities = 23/60 (38%), Positives = 27/60 (45%), Gaps = 7/60 (11%)
Query: 36 PGILPPMLPPMGAPPPLTQIPGMVPPMMPGMLMPAVPVTAATAPGADTASSAV--AGTGP 93
P LP +PP+ P P+T P VPP PG PV A P A T + G GP
Sbjct: 644 PKPLPVPVPPIPVPAPITVPPPQVPPHQPGP-----PVVGALQPPAFTPPLGIPPPGFGP 698
Score = 35.0 bits (79), Expect = 0.30
Identities = 26/117 (22%), Positives = 54/117 (46%), Gaps = 10/117 (8%)
Query: 712 SPSGSESEEEELPPPSLRPPKRRRRNP---SESGSEPSSSLDSVESGGAALGGRGSPSSH 768
+P + ++++ PPPS +PP +++ +++ + +S D G + G R
Sbjct: 940 APQQPQQQQQQQPPPSQQPPPTQQQPQQFRNDNRQQFNSGRDQERFGRRSFGNRVENDRE 999
Query: 769 LLGADHGLRKAKKPKKKTKKRRHKSNSPESE--TDPEEKAGKESDEKEQEQD-KDRE 822
+G R + +R SP+ + D EE+ + S +++E+D +DRE
Sbjct: 1000 ----RYGNRNDDRDNSNRDRREWGRRSPDRDRHRDLEERNRRSSGHRDRERDSRDRE 1052
Score = 33.1 bits (74), Expect = 1.1
Identities = 22/53 (41%), Positives = 24/53 (45%), Gaps = 5/53 (9%)
Query: 7 MPPPGIPPPF---PPMGLPPMSQRPPAIPPMPPGILPPMLPPMGAPPPLTQIP 56
+PP G P F P PPM+Q P IPP PP P PLTQ P
Sbjct: 344 LPPNGQMPGFGLLPTPPFPPMAQ--PVIPPTPPVQQPFQASFQAQNEPLTQKP 394
Score = 33.1 bits (74), Expect = 1.1
Identities = 18/45 (40%), Positives = 23/45 (51%), Gaps = 1/45 (2%)
Query: 191 QPQPPQPQPDPPPVPPGPTPVPTGLLEPE-PGGSEDCDVLEATQP 234
+P P P+P P PVPP P P P + P+ P V+ A QP
Sbjct: 638 EPVSPIPKPLPVPVPPIPVPAPITVPPPQVPPHQPGPPVVGALQP 682
Score = 32.7 bits (73), Expect = 1.5
Identities = 14/33 (42%), Positives = 17/33 (51%)
Query: 188 QTLQPQPPQPQPDPPPVPPGPTPVPTGLLEPEP 220
+T +P P P P PVP P PVP + P P
Sbjct: 633 ETSHTEPVSPIPKPLPVPVPPIPVPAPITVPPP 665
Score = 32.0 bits (71), Expect = 2.6
Identities = 21/63 (33%), Positives = 26/63 (41%), Gaps = 5/63 (7%)
Query: 15 PFPPMGLPPMSQRPPAIPPMPPGILPPMLPPMGAPPPLT---QIPGMVPPM--MPGMLMP 69
P P+ P PP P P + PP +PP PP+ Q P PP+ P P
Sbjct: 639 PVSPIPKPLPVPVPPIPVPAPITVPPPQVPPHQPGPPVVGALQPPAFTPPLGIPPPGFGP 698
Query: 70 AVP 72
VP
Sbjct: 699 GVP 701
Score = 31.2 bits (69), Expect = 4.4
Identities = 16/33 (48%), Positives = 17/33 (51%), Gaps = 1/33 (3%)
Query: 181 KQQQQLPQTLQPQPPQPQPDPPPVPPGPTPVPT 213
+Q QQ PQ PQ PQ Q P PP P PT
Sbjct: 930 QQPQQQPQPQAPQQPQQQQQQQP-PPSQQPPPT 961
Score = 30.4 bits (67), Expect = 7.4
Identities = 20/70 (28%), Positives = 34/70 (48%), Gaps = 1/70 (1%)
Query: 469 RALEREEEEERERARLRERRQQRKNREAFQTFLDELH-ETGQLHSMSTWMELYPAVSTDV 527
R+ R+ R+R +ERR + K RE Q L ++ ET + S + W+ +T
Sbjct: 448 RSRSRDRRRHSPRSRSQERRDREKERERRQKGLPQVKPETASVCSTTLWVGQLDKRTTQQ 507
Query: 528 RFANMLGQPG 537
A++L + G
Sbjct: 508 DVASLLEEFG 517
Score = 30.0 bits (66), Expect = 9.7
Identities = 22/74 (29%), Positives = 27/74 (36%), Gaps = 12/74 (16%)
Query: 13 PPPFPPMGLPPMSQRPPA---------IPPMPPGILPPMLPPMGAPPPLTQIPG---MVP 60
PPP P G P + PA P GI + PP Q+PG +
Sbjct: 299 PPPQAPFGFPGDGMQQPAYTQHQNMDQFQPRMMGIQQDPMHHQVPLPPNGQMPGFGLLPT 358
Query: 61 PMMPGMLMPAVPVT 74
P P M P +P T
Sbjct: 359 PPFPPMAQPVIPPT 372
>gi|40789229 splicing factor, arginine/serine-rich 15 isoform 1
[Homo sapiens]
Length = 1147
Score = 65.9 bits (159), Expect = 2e-10
Identities = 82/307 (26%), Positives = 104/307 (33%), Gaps = 67/307 (21%)
Query: 1 MMPPPFMPPPGIPPPFPPMGLPPMSQRPPAIPP------MPPGILPPMLPPMGAPPPLTQ 54
+ PP F PP GIPPP G+PP PP + P +PPG LPP G PPP+T
Sbjct: 695 LQPPAFTPPLGIPPPGFGPGVPPPPPPPPFLRPGFNPMHLPPGFLPP-----GPPPPITP 749
Query: 55 IPGMVPPMMPGMLMPAVPVTAATAPGADTASSAVAGTGPPRALWSEHVAPDGRIYYYNAD 114
+ PP P + ++P + DT G P + NA+
Sbjct: 750 PVSIPPPHTPPI---SIPNSTIAGINEDTTKDLSIGNPIPTVVSGAR---------GNAE 797
Query: 115 DKQSVWEKPSVLKSKAELLLSQCPWKEYKS-------DTGKPYYYNNQSKESRWTRPKDL 167
SV S + A L P + S G S RP
Sbjct: 798 SGDSVKMYGSAVPPAAPTNLPTPPVTQPVSLLGTQGVAPGPVIGLQAPSTGLLGARP--- 854
Query: 168 DDLEVLVKQEAAGKQQQQLPQTLQPQPPQPQP------DPPPVPPG-PTPVPTGLL---- 216
++ Q G L Q PP+P P PPP P G P P G+
Sbjct: 855 ---GLIPLQRPPGMPPPHL-QRFPLMPPRPMPPHMMHRGPPPGPGGFAMPPPHGMKGPFP 910
Query: 217 -----------------EPEPGGSEDCDVLEATQPLEQGFLQQLEEGPSSSGQHQPQQEE 259
P PGG ED D + QP +Q Q + P Q Q QQ
Sbjct: 911 PHGPFVRPGGMPGLGGPGPGPGGPEDRDGRQ--QPPQQPQQQPQPQAPQQPQQQQQQQPP 968
Query: 260 EESKPEP 266
+P P
Sbjct: 969 PSQQPPP 975
Score = 38.1 bits (87), Expect = 0.036
Identities = 45/217 (20%), Positives = 89/217 (41%), Gaps = 8/217 (3%)
Query: 176 QEAAGKQQQQLPQTLQPQPPQPQPDPP----PVPPGPTPVPTGLLEPEPGGSEDCDVLEA 231
Q+ A Q Q + Q QP+ Q DP P+PP GLL P V+
Sbjct: 328 QQPAYTQHQNMDQ-FQPRMMGIQQDPMHHQVPLPPNGQMPGFGLLPTPPFPPMAQPVIPP 386
Query: 232 TQPLEQGFLQ--QLEEGPSSSGQHQPQQEEEESKPEPERSGLSWSNREKAKQAFKELLRD 289
T P++Q F Q + P + HQ + E E+ + + +S + + +++ A + R
Sbjct: 387 TPPVQQPFQASFQAQNEPLTQKPHQQEMEVEQPCIQEVKRHMSDNRKSRSRSASRSPKRR 446
Query: 290 KAVPSNASWEQAMKMVVTDPRYSALPKLSEKKQAFNAYKAQREKEEKEEARLRAKEAKQ- 348
++ + S + + R + Q + +RE+ +K +++ + A
Sbjct: 447 RSRSGSRSRRSRHRRSRSRSRDRRRHSPRSRSQERRDREKERERRQKGLPQVKPETASVC 506
Query: 349 TLQHFLEQHERMTSTTRYRRAEQTFGELEVWAVVPER 385
+ ++ Q ++ T+ + FG +E ++P R
Sbjct: 507 STTLWVGQLDKRTTQQDVASLLEEFGPIESINMIPPR 543
Score = 35.4 bits (80), Expect = 0.23
Identities = 23/60 (38%), Positives = 27/60 (45%), Gaps = 7/60 (11%)
Query: 36 PGILPPMLPPMGAPPPLTQIPGMVPPMMPGMLMPAVPVTAATAPGADTASSAV--AGTGP 93
P LP +PP+ P P+T P VPP PG PV A P A T + G GP
Sbjct: 659 PKPLPVPVPPIPVPAPITVPPPQVPPHQPGP-----PVVGALQPPAFTPPLGIPPPGFGP 713
Score = 35.0 bits (79), Expect = 0.30
Identities = 26/117 (22%), Positives = 54/117 (46%), Gaps = 10/117 (8%)
Query: 712 SPSGSESEEEELPPPSLRPPKRRRRNP---SESGSEPSSSLDSVESGGAALGGRGSPSSH 768
+P + ++++ PPPS +PP +++ +++ + +S D G + G R
Sbjct: 955 APQQPQQQQQQQPPPSQQPPPTQQQPQQFRNDNRQQFNSGRDQERFGRRSFGNRVENDRE 1014
Query: 769 LLGADHGLRKAKKPKKKTKKRRHKSNSPESE--TDPEEKAGKESDEKEQEQD-KDRE 822
+G R + +R SP+ + D EE+ + S +++E+D +DRE
Sbjct: 1015 ----RYGNRNDDRDNSNRDRREWGRRSPDRDRHRDLEERNRRSSGHRDRERDSRDRE 1067
Score = 33.1 bits (74), Expect = 1.1
Identities = 22/53 (41%), Positives = 24/53 (45%), Gaps = 5/53 (9%)
Query: 7 MPPPGIPPPF---PPMGLPPMSQRPPAIPPMPPGILPPMLPPMGAPPPLTQIP 56
+PP G P F P PPM+Q P IPP PP P PLTQ P
Sbjct: 359 LPPNGQMPGFGLLPTPPFPPMAQ--PVIPPTPPVQQPFQASFQAQNEPLTQKP 409
Score = 33.1 bits (74), Expect = 1.1
Identities = 18/45 (40%), Positives = 23/45 (51%), Gaps = 1/45 (2%)
Query: 191 QPQPPQPQPDPPPVPPGPTPVPTGLLEPE-PGGSEDCDVLEATQP 234
+P P P+P P PVPP P P P + P+ P V+ A QP
Sbjct: 653 EPVSPIPKPLPVPVPPIPVPAPITVPPPQVPPHQPGPPVVGALQP 697
Score = 32.7 bits (73), Expect = 1.5
Identities = 14/33 (42%), Positives = 17/33 (51%)
Query: 188 QTLQPQPPQPQPDPPPVPPGPTPVPTGLLEPEP 220
+T +P P P P PVP P PVP + P P
Sbjct: 648 ETSHTEPVSPIPKPLPVPVPPIPVPAPITVPPP 680
Score = 32.0 bits (71), Expect = 2.6
Identities = 21/63 (33%), Positives = 26/63 (41%), Gaps = 5/63 (7%)
Query: 15 PFPPMGLPPMSQRPPAIPPMPPGILPPMLPPMGAPPPLT---QIPGMVPPM--MPGMLMP 69
P P+ P PP P P + PP +PP PP+ Q P PP+ P P
Sbjct: 654 PVSPIPKPLPVPVPPIPVPAPITVPPPQVPPHQPGPPVVGALQPPAFTPPLGIPPPGFGP 713
Query: 70 AVP 72
VP
Sbjct: 714 GVP 716
Score = 31.2 bits (69), Expect = 4.4
Identities = 16/33 (48%), Positives = 17/33 (51%), Gaps = 1/33 (3%)
Query: 181 KQQQQLPQTLQPQPPQPQPDPPPVPPGPTPVPT 213
+Q QQ PQ PQ PQ Q P PP P PT
Sbjct: 945 QQPQQQPQPQAPQQPQQQQQQQP-PPSQQPPPT 976
Score = 30.4 bits (67), Expect = 7.4
Identities = 20/70 (28%), Positives = 34/70 (48%), Gaps = 1/70 (1%)
Query: 469 RALEREEEEERERARLRERRQQRKNREAFQTFLDELH-ETGQLHSMSTWMELYPAVSTDV 527
R+ R+ R+R +ERR + K RE Q L ++ ET + S + W+ +T
Sbjct: 463 RSRSRDRRRHSPRSRSQERRDREKERERRQKGLPQVKPETASVCSTTLWVGQLDKRTTQQ 522
Query: 528 RFANMLGQPG 537
A++L + G
Sbjct: 523 DVASLLEEFG 532
Score = 30.0 bits (66), Expect = 9.7
Identities = 22/74 (29%), Positives = 27/74 (36%), Gaps = 12/74 (16%)
Query: 13 PPPFPPMGLPPMSQRPPA---------IPPMPPGILPPMLPPMGAPPPLTQIPG---MVP 60
PPP P G P + PA P GI + PP Q+PG +
Sbjct: 314 PPPQAPFGFPGDGMQQPAYTQHQNMDQFQPRMMGIQQDPMHHQVPLPPNGQMPGFGLLPT 373
Query: 61 PMMPGMLMPAVPVT 74
P P M P +P T
Sbjct: 374 PPFPPMAQPVIPPT 387
>gi|146134388 YLP motif containing 1 [Homo sapiens]
Length = 2146
Score = 65.5 bits (158), Expect = 2e-10
Identities = 54/163 (33%), Positives = 68/163 (41%), Gaps = 20/163 (12%)
Query: 2 MPPPFMPP--------PGIPPPFPPMGLPPMSQRPPAIPPMPPGILPPMLPPMGAPPPLT 53
MPPP MPP PG+PP G PP+ P PP +LPP APPP+
Sbjct: 560 MPPPVMPPSLPTSVPPPGMPPSLSSAGPPPVLPPPSLSSAGPPPVLPPPSLSSTAPPPVM 619
Query: 54 QIPGM---VPPMMPGMLMPAVP------VTAATAPGADTASSAVAGTGPPRALWSEHVAP 104
+P + PP PG+ P VP +TAA P A ++ S+ P AL V+
Sbjct: 620 PLPPLSSATPP--PGIPPPGVPQGIPPQLTAAPVPPASSSQSSQVPEKPRPALLPTPVSF 677
Query: 105 DGRIYYYNADDKQSVWEKPSVLKSKAELLLSQCPWKEYKSDTG 147
QS V SKA L S P+ + SD G
Sbjct: 678 GSAPPTTYHPPLQSAGPSEQV-NSKAPLSKSALPYSSFSSDQG 719
Score = 64.7 bits (156), Expect = 4e-10
Identities = 38/96 (39%), Positives = 48/96 (50%), Gaps = 10/96 (10%)
Query: 2 MPPPFMPPPGIPPPFPPMGLPPMSQRPPAIPPMPPGILPPMLPPMGAPPPLTQIPGMVPP 61
M +M +PPPF P SQ PP +P MPP +LPP LPP PP L P VPP
Sbjct: 506 MKNQYMGNMSMPPPFVPY-----SQMPPPLPTMPPPVLPPSLPPPVMPPAL---PATVPP 557
Query: 62 MMPGMLMPAVPVTAATAPGADTASSAVAGTGPPRAL 97
PGM P +P + T+ +++ GPP L
Sbjct: 558 --PGMPPPVMPPSLPTSVPPPGMPPSLSSAGPPPVL 591
Score = 59.7 bits (143), Expect = 1e-08
Identities = 38/100 (38%), Positives = 52/100 (52%), Gaps = 14/100 (14%)
Query: 2 MPPPFMPPPGIPPPFPPMGLPPMSQRPPAIPP--MPPGILPPMLPPMGAPPPL--TQIPG 57
MPPPF+P +PPP P M P + PP++PP MPP + +PP G PPP+ +P
Sbjct: 516 MPPPFVPYSQMPPPLPTMPPPVL---PPSLPPPVMPPALPA-TVPPPGMPPPVMPPSLPT 571
Query: 58 MVPPMMPGMLMPAVPVTAATAPGADTASSAVAGTGPPRAL 97
VPP PGM P ++ P +++ GPP L
Sbjct: 572 SVPP--PGM----PPSLSSAGPPPVLPPPSLSSAGPPPVL 605
Score = 55.1 bits (131), Expect = 3e-07
Identities = 67/269 (24%), Positives = 103/269 (38%), Gaps = 18/269 (6%)
Query: 3 PPPFMPPPGIPPPFPP--MGLPPMSQR--PPAIPP--MPPGILPPMLPPMGAPPPLTQIP 56
PPP +PPP + PP M LPP+S PP IPP +P GI PP L PP +
Sbjct: 601 PPPVLPPPSLSSTAPPPVMPLPPLSSATPPPGIPPPGVPQGI-PPQLTAAPVPPASSSQS 659
Query: 57 GMVPPMMPGMLMPAVPVTAATAPGADTASSAVAGTGPPRALWSEHVAPDGRIYYYNADDK 116
VP L+P PV+ +AP T + GP + S+ + Y +
Sbjct: 660 SQVPEKPRPALLP-TPVSFGSAP-PTTYHPPLQSAGPSEQVNSKAPLSKSALPYSSFSSD 717
Query: 117 QSVWEKPSVLKSKAELLLSQCPWKEYKSDTGKP-YYYNNQSKESRWTRPKDLDDLEVLVK 175
Q + E S S+ + P + P Y + R+ P+ +DL
Sbjct: 718 QGLGES-SAAPSQPITAVKDMPVRSGGLLPDPPRSSYLESPRGPRFDGPRRFEDL----G 772
Query: 176 QEAAGKQQQQLPQTLQPQPPQPQPDPPPVPPGPTPVPTGLLEPEPGGSEDCDVLEATQPL 235
G + + P+ +P P+P P T G++ P + P
Sbjct: 773 SRCEGPRPKG-PRFEGNRPDGPRPRYEGHPAEGTKSKWGMIPRGPASQFYITPSTSLSPR 831
Query: 236 EQGFLQQLEEGPSSSGQHQPQQEEEESKP 264
+ G Q + + GQ QQ + +++P
Sbjct: 832 QSG--PQWKGPKPAFGQQHQQQPKSQAEP 858
Score = 47.8 bits (112), Expect = 5e-05
Identities = 79/336 (23%), Positives = 117/336 (34%), Gaps = 98/336 (29%)
Query: 1 MMPPPFMPPPGIP--------------PPFPPM--------------------------- 19
++ P +PPP +P PP PPM
Sbjct: 75 VLQPHHLPPPPLPPPPVMPGGGYGDWQPPPPPMPPPPGPALSYQKQQQYKHQMLHHQRDG 134
Query: 20 --GLPPMS-QRPPAIPPMPPG--------ILPPMLPPMGAPPPLTQIPGMVPPM-MPGML 67
GL PM + PP PP+PPG +PP PP PP + P + P P
Sbjct: 135 PPGLVPMELESPPESPPVPPGSYMPPSQSYMPPPQPPPSYYPPTSSQPYLPPAQPSPSQS 194
Query: 68 MPAVPVTAATAPGADTASSAVAGTGPPRA-LWSEHVAPDGRIYYYNAD------------ 114
P+ A T + ++SS+ + ++ L S +P ++
Sbjct: 195 PPSQSYLAPTPSYSSSSSSSQSYLSHSQSYLPSSQASPSRPSQGHSKSQLLAPPPPSAPP 254
Query: 115 -DKQSVWEKPSVLKSKAELLLSQCPWKEYKSDTGKPYYYNNQSKESRWTRPKDLDDLEVL 173
+K +V ++P +K + Q E T P Q ++ W R + L L+
Sbjct: 255 GNKTTVQQEPLESGAKNKSTEQQQAAPEPDPSTMTP-----QEQQQYWYR-QHLLSLQQR 308
Query: 174 VKQEAAG---------------KQQQQLPQTLQPQPPQPQPDPPPVPPGPTPVPTGLLEP 218
K G K++ +P T Q P P + PP+PP VP L P
Sbjct: 309 TKVHLPGHKKGPVVAKDTPEPVKEEVTVPATSQ-VPESPSSEEPPLPPPNEEVPPP-LPP 366
Query: 219 EPGGSEDCDVLEATQPLEQGFLQQLEEGPSSSGQHQ 254
E SED P E L+QL+ + QHQ
Sbjct: 367 EEPQSED--------PEEDARLKQLQAAAAHWQQHQ 394
Score = 47.4 bits (111), Expect = 6e-05
Identities = 27/62 (43%), Positives = 32/62 (51%), Gaps = 4/62 (6%)
Query: 4 PPFMPPPGIPPPFPPMGLPPMSQRPPAIPP---MPPGILPPM-LPPMGAPPPLTQIPGMV 59
P PPPG P PPMG PP S P+ PP P PP+ +PP PPPL P ++
Sbjct: 1503 PGMYPPPGSYRPPPPMGKPPGSIVRPSAPPARSSVPVTRPPVPIPPPPPPPPLPPPPPVI 1562
Query: 60 PP 61
P
Sbjct: 1563 KP 1564
Score = 39.7 bits (91), Expect = 0.012
Identities = 122/570 (21%), Positives = 198/570 (34%), Gaps = 116/570 (20%)
Query: 4 PPFMPPPGIPPPFPPMGLPPMSQRPPAIPPMPPGI------------------------- 38
P PP IPPP PP LPP PP I P +
Sbjct: 1538 PVTRPPVPIPPPPPPPPLPPP---PPVIKPQTSAVEQERWDEDSFYGLWDTNDEQGLNSE 1594
Query: 39 -------LP--PMLPPMGAPPPLTQI--PGMVPPMMPGMLM-PAVPVTAATAPGADTASS 86
+P P+LPP PP + I PG VP MP M P V T G D +++
Sbjct: 1595 FKSETAAIPSAPVLPP---PPVHSSIPPPGPVPMGMPPMSKPPPVQQTVDYGHGRDISTN 1651
Query: 87 AVAGTG------------PPRALW-SEHVAPDGRIYYYNADDKQSVWEKPS-VLKSKAEL 132
V P R+ + +EH R Y D++ +++ S V+ +
Sbjct: 1652 KVEQIPYGERITLRPDPLPERSTFETEHAGQRDR--YDRERDREPYFDRQSNVIADHRDF 1709
Query: 133 LLSQCPWKEYKSDTGKPYYYNNQSKESRWTRPKDLDDLEVLVKQEAAGKQQQQLPQTLQP 192
+ ++ D G Y ++ + R RP+D K++ + ++
Sbjct: 1710 KRDRETHRDRDRDRGVIDY--DRDRFDRERRPRDDRAQSYRDKKDHSSSRRGGF-----D 1762
Query: 193 QPPQPQPDPPPVPPGPTPVPTGLLEPEPGGSEDCDVLEATQPLEQGFLQQLEEGPSSSGQ 252
+P + PV GP+ G E E PL P+ S
Sbjct: 1763 RPSYDRKSDRPVYEGPSMF----------GGERRTYPEERMPL-----------PAPSLS 1801
Query: 253 HQPQQEEE-ESKPEPERSG--LSWSNREKAKQAFKELLRDKAVPSNASWEQAMKMVVTDP 309
HQP E KPE + L RE + ++R +P + A ++ D
Sbjct: 1802 HQPPPAPRVEKKPESKNVDDILKPPGRESRPERIVVIMR--GLPGSGKTHVA--KLIRDK 1857
Query: 310 RYSALPKLSEKKQAFNAYKAQREKEEKEEARLRAKEAKQTLQHFLEQHERMTSTTRYRRA 369
+ + + EKEEK+ + + K + + E T+ ++
Sbjct: 1858 EVEFGGPAPRVLSLDDYFITEVEKEEKDPDSGKKVKKKVMEYEYEAEMEETYRTSMFKTF 1917
Query: 370 EQTFGELEVWAVVPE--RDRKEVYDDVLFFLAKKEK----------EQAKQLRRRNIQAL 417
++T + ++ + DR +D F+ A K K + +RNI
Sbjct: 1918 KKTLDDGFFPFIILDAINDRVRHFDQ--FWSAAKTKGFEVYLAEMSADNQTCGKRNIHGR 1975
Query: 418 KSILDGMSSVN-FQTTWSQAQQYLM--DNPSFAQDHQLQNMDKEDALICFEEHIRALERE 474
K + +N W A +++M D S QD ++ ++ ED EE +
Sbjct: 1976 K-----LKEINKMADHWETAPRHMMRLDIRSLLQDAAIEEVEMEDFDANIEEQKEEKKDA 2030
Query: 475 EEEERERARLRERRQQRKNREAFQTFLDEL 504
EEEE E + + + + EA LD L
Sbjct: 2031 EEEESELGYIPKSKWEMDTSEAKLDKLDGL 2060
Score = 33.5 bits (75), Expect = 0.88
Identities = 37/173 (21%), Positives = 65/173 (37%), Gaps = 11/173 (6%)
Query: 174 VKQEAAGKQQQQLPQTLQPQPPQPQPDPPPVPPGPTPV--PTGLLEPEPGGSEDCDVLEA 231
+ + +A + +P T P P P P PPP+PP P + T +E E + L
Sbjct: 1525 IVRPSAPPARSSVPVTRPPVPIPPPPPPPPLPPPPPVIKPQTSAVEQERWDEDSFYGLWD 1584
Query: 232 T---QPLEQGFLQQLEEGPSSSGQHQPQQEEEESKPEPERSGLSWSNREKAKQAFKELLR 288
T Q L F + PS+ P P P G+ ++ Q +
Sbjct: 1585 TNDEQGLNSEFKSETAAIPSAPVLPPPPVHSSIPPPGPVPMGMPPMSKPPPVQQTVDYGH 1644
Query: 289 DKAVPSNASWEQAMKMVVTDPRYSALP-KLSEKKQAFNAYKAQREKEEKEEAR 340
+ + +N ++ + R + P L E+ + QR++ ++E R
Sbjct: 1645 GRDISTN-----KVEQIPYGERITLRPDPLPERSTFETEHAGQRDRYDRERDR 1692
Score = 33.1 bits (74), Expect = 1.1
Identities = 49/227 (21%), Positives = 82/227 (36%), Gaps = 50/227 (22%)
Query: 163 RPKDLDDLEVLVKQEAAGKQQQQLPQTLQPQPPQP------------QPDPPPVPPGPTP 210
R + L L+ L + Q P L P P P QP PPP+PP P P
Sbjct: 54 REQHLAQLQQLQQMHQKQMQCVLQPHHLPPPPLPPPPVMPGGGYGDWQPPPPPMPPPPGP 113
Query: 211 V--------------------PTGLLEPEPGGSEDCDVLE--ATQPLEQGFLQQLEEGPS 248
P GL+ E + + + P Q ++ + PS
Sbjct: 114 ALSYQKQQQYKHQMLHHQRDGPPGLVPMELESPPESPPVPPGSYMPPSQSYMPPPQPPPS 173
Query: 249 -----SSGQHQPQQEEEESKPEPERSGL----SWSNREKAKQAF-----KELLRDKAVPS 294
SS + P + S+ P +S L S+S+ + Q++ L +A PS
Sbjct: 174 YYPPTSSQPYLPPAQPSPSQSPPSQSYLAPTPSYSSSSSSSQSYLSHSQSYLPSSQASPS 233
Query: 295 NASWEQAMKMVVTDPRYSALP--KLSEKKQAFNAYKAQREKEEKEEA 339
S + ++ P SA P K + +++ + + E+++ A
Sbjct: 234 RPSQGHSKSQLLAPPPPSAPPGNKTTVQQEPLESGAKNKSTEQQQAA 280
Score = 32.7 bits (73), Expect = 1.5
Identities = 65/299 (21%), Positives = 97/299 (32%), Gaps = 58/299 (19%)
Query: 8 PPPGIPPPFPPMGLPPMSQRP-------PAIP--------------------PMPPGILP 40
PPP +PPP PP+ LP S P PA P M +
Sbjct: 15 PPPPVPPP-PPVALPEASPGPGYSSSTTPAAPSSSGFMSFREQHLAQLQQLQQMHQKQMQ 73
Query: 41 PMLPPMGAPPPLTQIPGMVPPMMPG-----MLMPAVPVTAATAPGADTASSAVAGTGPPR 95
+L P PPP P PP+MPG P P+ P S +
Sbjct: 74 CVLQPHHLPPP----PLPPPPVMPGGGYGDWQPPPPPMPPPPGP---ALSYQKQQQYKHQ 126
Query: 96 ALWSEHVAPDGRIYYYNADDKQSVWEKPS--VLKSKAELLLSQCPWKEYKSDTGKPYYYN 153
L + P G + +S P + S++ + Q P Y + +PY
Sbjct: 127 MLHHQRDGPPGLVPMELESPPESPPVPPGSYMPPSQSYMPPPQPPPSYYPPTSSQPYLPP 186
Query: 154 NQSKESRWTRPKDLDDLEVLVKQEAAGKQQQQLPQTLQPQPPQPQPDPPPVPPGPTPVPT 213
Q S+ P L ++ Q Q P Q P G + +
Sbjct: 187 AQPSPSQ--SPPSQSYLAPTPSYSSSSSSSQSYLSHSQSYLPSSQASPSRPSQGHS--KS 242
Query: 214 GLLEPEPGGSEDCDVLEATQPLEQGFLQQLEEGPSSSGQHQPQQEEEESKPEPERSGLS 272
LL P P + G +++ P SG E++++ PEP+ S ++
Sbjct: 243 QLLAPPPPSA------------PPGNKTTVQQEPLESGAKNKSTEQQQAAPEPDPSTMT 289
>gi|7662046 myeloid/lymphoid or mixed-lineage leukemia 4 [Homo
sapiens]
Length = 2715
Score = 63.2 bits (152), Expect = 1e-09
Identities = 68/229 (29%), Positives = 83/229 (36%), Gaps = 55/229 (24%)
Query: 3 PPPFMPP-PGIPPPFPPMGLPPMSQRPPAIPPMPPGILPPMLPPMGAPPPLTQIPGMVPP 61
PPP PP P PPP PP P S PP PP PP + PP LP PP + PP
Sbjct: 403 PPPLTPPAPSPPPPLPP---PSTSPPPPLCPPPPPPVSPPPLPSPPPPPAQEEQEESPPP 459
Query: 62 MMPGMLM------PAVPVTAA-----------TAPGADTASSAVAGTGPPRALWSEHVAP 104
++P P P A T+P T S+A GPP S VAP
Sbjct: 460 VVPATCSRKRGRPPLTPSQRAEREAARAGPEGTSPPTPTPSTATG--GPPED--SPTVAP 515
Query: 105 DGRIYYYNADDKQSVWEKPSVLKSKAELLLSQCPWKEYKSDTGKPYYYNNQSKESRWTRP 164
+ N +Q + S S+ + + P + D KP + + S RP
Sbjct: 516 KSTTFLKNI--RQFIMPVVSARSSR----VIKTPRRFMDEDPPKP----PKVEVSPVLRP 565
Query: 165 KDLDDLEVLVKQEAAGKQQQQLPQTLQPQPPQPQPDPPPVP-PGPTPVP 212
V PQ P P P PP P P TPVP
Sbjct: 566 PITTSPPV-------------------PQEPAPVPSPPRAPTPPSTPVP 595
Score = 44.7 bits (104), Expect = 4e-04
Identities = 97/391 (24%), Positives = 132/391 (33%), Gaps = 73/391 (18%)
Query: 1 MMPPPFMPPPGIPPPFPPMGLPPMSQRPPAIP-PMPPGILPPMLPPMGAPPPLTQI---P 56
++ PP P +P P+ PP + PP+ P P+P + P LT+ P
Sbjct: 562 VLRPPITTSPPVPQEPAPVPSPPRAPTPPSTPVPLPEKRRSILREPTFRWTSLTRELPPP 621
Query: 57 GMVPPMMPGMLMPAVPVTAATAPGADTASSAVAGTG----------PPRALWSEHVAPDG 106
PP P P P T++ P A PP E P+
Sbjct: 622 PPAPPPPPAPSPPPAPATSSRRPLLLRAPQFTPSEAHLKIYESVLTPPPLGAPEAPEPEP 681
Query: 107 RIYYYNADDKQSVWEKPSVLKSKAELL-----LSQCPWKEYKSDTGKPYYYNNQSKESRW 161
ADD + E +V ++ L + P K S G P N +++
Sbjct: 682 P----PADDSPAEPEPRAVGRTNHLSLPRFAPVVTTPVKAEVSPHGAPALSNGPQTQAQL 737
Query: 162 TRPKDLDDLEVLVKQEAAGKQQQQLPQTLQPQPPQPQPDPPPVPPGPTPVPTGLLE---- 217
+P L+ L Q Q LPQ L PPQPQ PPP P P+ +
Sbjct: 738 LQP-----LQAL--------QTQLLPQALP--PPQPQLQPPPSPQQMPPLEKARIAGVGS 782
Query: 218 -PEPGGSEDC-------------------DVLEATQPLEQGFLQQLEEGPSSSGQ---HQ 254
P G E + A+ PL G Q+EE + Q
Sbjct: 783 LPLSGVEEKMFSLLKRAKVQLFKIDQQQQQKVAASMPLSPG--GQMEEVAGAVKQISDRG 840
Query: 255 PQQEEEESKPEPERSGLSWSNREKAKQAFKELLRDKAVPSNASWEQAMKMVVTD-PRYSA 313
P + E+ES E +R S K + R AV + QA MV D PR SA
Sbjct: 841 PVRSEDES-VEAKRERPSGPESPVQGPRIKHVCRHAAV----ALGQARAMVPEDVPRLSA 895
Query: 314 LPKLSEKKQAFNAYKAQREKEEKEEARLRAK 344
LP + A + E E R K
Sbjct: 896 LPLRDRQDLATEDTSSASETESVPSRSRRGK 926
Score = 39.3 bits (90), Expect = 0.016
Identities = 60/268 (22%), Positives = 90/268 (33%), Gaps = 71/268 (26%)
Query: 7 MPPPGIPPPFPPMGLPPMSQRPPAIPPMPPGILPPMLPPMG----APPPLTQIPGMVPPM 62
+PPP PP PP +S P +PPG L +LP +G APPP PP
Sbjct: 2211 VPPPVKQPPLPPT----ISPTAPTSWTLPPGPLLGVLPVVGVVRPAPPP--------PPP 2258
Query: 63 MPGMLMPAVPVTAATAPGADTASSAVAGTGPPRALWSEHVAPDGRIYYYNADDKQSVWEK 122
+++ + P + S +G PP AP +D ++ +
Sbjct: 2259 PLTLVLSSGPASPPRQAIRVKRVSTFSGRSPP--------APPPYKAPRLDEDGEASEDT 2310
Query: 123 PSVLKSKAELLLSQCPWKEYKSDTGKPYYYNNQSKESRWTRPKDLDDLEVLVKQEAAGKQ 182
P V P + R P L++ E AG++
Sbjct: 2311 PQV-----------------------PGLGSGGFSRVRMKTPTVRGVLDLDRPGEPAGEE 2347
Query: 183 QQQLPQTLQPQPPQPQPDPPPVPPGPTPVPTGLLEPEPGGSEDCDVLEATQPLEQGFLQQ 242
Q P P P+ PP VP GP P LLE +
Sbjct: 2348 SPGPLQERSPLLPLPEDGPPQVPDGP---PDLLLESQ---------------------WH 2383
Query: 243 LEEGPSSSGQHQPQQEEEESKPEPERSG 270
G +SS + +P +++ P+R+G
Sbjct: 2384 HYSGEASSSEEEPPSPDDKENQAPKRTG 2411
Score = 36.2 bits (82), Expect = 0.14
Identities = 22/79 (27%), Positives = 33/79 (41%), Gaps = 7/79 (8%)
Query: 187 PQTLQPQPPQPQPDPPPVPPGPTPVPTGLLEPEPGGSEDCDVLEATQPLEQGFLQQLEEG 246
P + P PP P PPPV P P P P P P E+ + E+ P+ +
Sbjct: 419 PPSTSPPPPLCPPPPPPVSPPPLPSP-----PPPPAQEEQE--ESPPPVVPATCSRKRGR 471
Query: 247 PSSSGQHQPQQEEEESKPE 265
P + + ++E + PE
Sbjct: 472 PPLTPSQRAEREAARAGPE 490
Score = 35.4 bits (80), Expect = 0.23
Identities = 51/223 (22%), Positives = 74/223 (33%), Gaps = 50/223 (22%)
Query: 23 PMSQRPPAIPPMPPGILPPMLPPMGAPPPLTQIPGMVPPMMPGMLMPAVPVTAATAPGAD 82
P +++ A P PP P PP PPP T P PP+ P P P + P
Sbjct: 392 PAAEKEEAKLPPPPLTPPAPSPPPPLPPPSTSPP---PPLCPPPPPPVSPPPLPSPP--- 445
Query: 83 TASSAVAGTGPPRALWSEHVAPDGRIYYYNADDKQSVWEKPSVLKSKAELLLSQC----- 137
PP A + +P + A + P +AE ++
Sbjct: 446 ----------PPPAQEEQEESPPPVV---PATCSRKRGRPPLTPSQRAEREAARAGPEGT 492
Query: 138 --PWKEYKSDTGKPYYYNNQSKESRWTRPKDLDDLE---------VLVKQEAAGKQQQQL 186
P + TG P ++S PK L+ V + K ++
Sbjct: 493 SPPTPTPSTATGGP------PEDSPTVAPKSTTFLKNIRQFIMPVVSARSSRVIKTPRRF 546
Query: 187 PQTLQPQPPQPQPDP---------PPVPPGPTPVPTGLLEPEP 220
P+PP+ + P PPVP P PVP+ P P
Sbjct: 547 MDEDPPKPPKVEVSPVLRPPITTSPPVPQEPAPVPSPPRAPTP 589
Score = 35.0 bits (79), Expect = 0.30
Identities = 26/89 (29%), Positives = 32/89 (35%), Gaps = 22/89 (24%)
Query: 178 AAGKQQQQLPQTLQPQPPQPQPDPPPVPPGPTPVPTGLLEPEPGGSEDCDVLEATQPLEQ 237
AA K++ +LP PP P P PP PP +P P P P
Sbjct: 393 AAEKEEAKLPPP-PLTPPAPSPPPPLPPPSTSPPPPLCPPPPP----------------- 434
Query: 238 GFLQQLEEGPSSSGQHQPQQEEEESKPEP 266
+ P S P QEE+E P P
Sbjct: 435 ----PVSPPPLPSPPPPPAQEEQEESPPP 459
Score = 35.0 bits (79), Expect = 0.30
Identities = 35/112 (31%), Positives = 42/112 (37%), Gaps = 33/112 (29%)
Query: 7 MPPPGIP------------PPFPPMGLPPMSQRPPAIPPMPPGILPPMLPPMGAPPPLTQ 54
+P PG P P FP P S+RP + P PP P A PPL
Sbjct: 1885 LPSPGSPSSLTHHIPTVGDPDFPAP--PRRSRRPSPLAPRPP-------PSRWASPPLKT 1935
Query: 55 IPGM-VPPMMPGMLMPAVPVTAATAPGADTASSAVAGTGPPRALWSEHVAPD 105
P + VPP P VTA T + A A + PP E + PD
Sbjct: 1936 SPQLRVPP-------PTSVVTALTPTSGELAPPGPAPSPPP----PEDLGPD 1976
>gi|4508017 zinc finger protein 207 isoform a [Homo sapiens]
Length = 478
Score = 62.0 bits (149), Expect = 2e-09
Identities = 37/100 (37%), Positives = 49/100 (49%), Gaps = 13/100 (13%)
Query: 4 PPFMPPPGIPPPFPPM--GLPPMSQRPPAIPPMPPGILPPMLPPMGAPPPLTQIPGMVPP 61
PP PG+PP PP+ G+PP+ P +PP+ PG+ P M+P G PP IP ++P
Sbjct: 148 PPVPGAPGMPPGIPPLMPGVPPLM---PGMPPVMPGMPPGMMPMGGMMPPGPGIPPLMPG 204
Query: 62 MMPGM--------LMPAVPVTAATAPGADTASSAVAGTGP 93
M PGM + P A +APG A T P
Sbjct: 205 MPPGMPPPVPRPGIPPMTQAQAVSAPGILNRPPAPTATVP 244
Score = 58.5 bits (140), Expect = 3e-08
Identities = 77/293 (26%), Positives = 114/293 (38%), Gaps = 66/293 (22%)
Query: 2 MPP--PFMPP--PGIPPPFPPMG--LPPMSQRPPAIPPMPPGILPPMLPPMGAPPPLTQ- 54
+PP P MPP PG+PP PMG +PP PP +P MPPG +PP +P G PP+TQ
Sbjct: 167 VPPLMPGMPPVMPGMPPGMMPMGGMMPPGPGIPPLMPGMPPG-MPPPVPRPGI-PPMTQA 224
Query: 55 ----IPGMV-PPMMPGMLMPA--VPVTAATAPGADTASSAVAGTGPPRALWSEHVAPDGR 107
PG++ P P +PA PVT P A + V + + SE ++ +
Sbjct: 225 QAVSAPGILNRPPAPTATVPAPQPPVTKPLFPSAGQMGTPVTSSSTASSN-SESLSASSK 283
Query: 108 IYYYNADDKQSVWEK------------------------PSVLKSKAEL--LLSQCPWKE 141
+ + Q+ + P+ +S A + K
Sbjct: 284 ALFPSTAQAQAAVQGPVGTDFKPLNSTPATTTEPPKPTFPAYTQSTASTTSTTNSTAAKP 343
Query: 142 YKSDTGKPYYYNNQSKESRWTRPKDLDDLEVLVKQEAAGKQQQQLPQTLQPQPPQPQPDP 201
S T KP S S+ P +D+ + ++ K Q+ LP+ Q P +P
Sbjct: 344 AASITSKPATLTTTSATSKLIHPD--EDISLEERRAQLPKYQRNLPRPGQ----APIGNP 397
Query: 202 PPVPPGPTPVPTGLLEPEPGGSEDCDVLEATQPLEQGFLQQLEEGPSSSGQHQ 254
P P G G++ P+PG P +QG + G HQ
Sbjct: 398 PVGPIG------GMMPPQPG-----------IPQQQGMRPPMPPHGQYGGHHQ 433
Score = 57.0 bits (136), Expect = 7e-08
Identities = 40/107 (37%), Positives = 51/107 (47%), Gaps = 21/107 (19%)
Query: 3 PPPFMPPPGIPPPFPPMGLPPMSQRP---PAIPPMPPGI---LPPMLPPM-GAPPPLTQI 55
P P P G PP GLPP+ P P IPP+ PG+ +P M P M G PP + +
Sbjct: 129 PQPVQPQQGYIPPMAQPGLPPVPGAPGMPPGIPPLMPGVPPLMPGMPPVMPGMPPGMMPM 188
Query: 56 PGM------VPPMMPGM---LMPAVPVTAATAPGADTASSAVAGTGP 93
GM +PP+MPGM + P VP PG + A A + P
Sbjct: 189 GGMMPPGPGIPPLMPGMPPGMPPPVP-----RPGIPPMTQAQAVSAP 230
Score = 40.0 bits (92), Expect = 0.009
Identities = 31/77 (40%), Positives = 36/77 (46%), Gaps = 23/77 (29%)
Query: 1 MMPPPFMPPPGIP------PPFPP--------MGLPPMSQRPPAIPPMPPGILPPMLPPM 46
MMPP PGIP PP PP G+P P A+PP G PPM+PP
Sbjct: 405 MMPPQ----PGIPQQQGMRPPMPPHGQYGGHHQGMP--GYLPGAMPPYGQG--PPMVPPY 456
Query: 47 GAPPPLTQIPGMVPPMM 63
PP + GM PP+M
Sbjct: 457 QGGPPRPPM-GMRPPVM 472
Score = 39.3 bits (90), Expect = 0.016
Identities = 27/75 (36%), Positives = 31/75 (41%), Gaps = 17/75 (22%)
Query: 4 PPFMPPPGIPPPFPPMGLPPMSQRPPAIPPMP---------PGILPPMLPPMGAPPPLTQ 54
PP P G+ PP P G+P P +PP PG LP +PP G PP
Sbjct: 397 PPVGPIGGMMPPQP--GIPQQQGMRPPMPPHGQYGGHHQGMPGYLPGAMPPYGQGPP--- 451
Query: 55 IPGMVPPMMPGMLMP 69
MVPP G P
Sbjct: 452 ---MVPPYQGGPPRP 463
Score = 34.3 bits (77), Expect = 0.52
Identities = 24/71 (33%), Positives = 32/71 (45%), Gaps = 6/71 (8%)
Query: 155 QSKESRWTRPKDLDDLEVLVKQEAAGKQQQQLPQTLQPQ----PPQPQPDPPPVPPGPTP 210
+ K + K DD + ++A Q PQ +QPQ PP QP PPVP P
Sbjct: 98 EQKTQESQKKKQQDDSDEYDDDDSAASTSFQ-PQPVQPQQGYIPPMAQPGLPPVPGAP-G 155
Query: 211 VPTGLLEPEPG 221
+P G+ PG
Sbjct: 156 MPPGIPPLMPG 166
>gi|157168329 formin 1 [Homo sapiens]
Length = 1196
Score = 61.2 bits (147), Expect = 4e-09
Identities = 30/63 (47%), Positives = 32/63 (50%), Gaps = 4/63 (6%)
Query: 4 PPFMPPPGIPPPFPPMGLPPMSQRPPAIPPMPPGILPPMLPPMGAPPPLTQIPGMVPPMM 63
PP PPP PPP PP P S PP PP PP P P G PPP PG+ PP
Sbjct: 678 PPLPPPPPPPPPLPP----PSSAGPPPPPPPPPLPNSPAPPNPGGPPPAPPPPGLAPPPP 733
Query: 64 PGM 66
PG+
Sbjct: 734 PGL 736
Score = 49.3 bits (116), Expect = 2e-05
Identities = 51/185 (27%), Positives = 76/185 (41%), Gaps = 34/185 (18%)
Query: 2 MPPP---FMPPPGIPP------PFPPMGLPPMSQRPPAIPPMPPG--ILPPMLPPMGAPP 50
+PPP PPP +P P PPM PP+S PP PP PP + PP PP
Sbjct: 645 LPPPPASIPPPPPLPSGLGSLSPAPPM--PPVSAGPPLPPPPPPPPPLPPPSSAGPPPPP 702
Query: 51 PLTQIPGMVPPMMPGMLMPAVPVTAATAP-------GADTASS------AVAGTGPPRAL 97
P +P P PG PA P P G ++SS A+ + P + L
Sbjct: 703 PPPPLPNSPAPPNPGGPPPAPPPPGLAPPPPPGLFFGLGSSSSQCPRKPAIEPSCPMKPL 762
Query: 98 WSEHVAPDGRIYYYNADDKQSVW---EKPSVL-KSKAELLLSQCPWKEYKSDTGKPYYYN 153
+ + R + + ++W E+P + S+ E L S+ ++ K + Y
Sbjct: 763 YWTRIQISDR----SQNATPTLWDSLEEPDIRDPSEFEYLFSKDTTQQKKKPLSETYEKK 818
Query: 154 NQSKE 158
N+ K+
Sbjct: 819 NKVKK 823
Score = 38.5 bits (88), Expect = 0.027
Identities = 17/35 (48%), Positives = 18/35 (51%), Gaps = 4/35 (11%)
Query: 192 PQPPQPQPDP----PPVPPGPTPVPTGLLEPEPGG 222
P PP P P P PP PP P P+P P PGG
Sbjct: 684 PPPPPPLPPPSSAGPPPPPPPPPLPNSPAPPNPGG 718
Score = 33.9 bits (76), Expect = 0.67
Identities = 17/38 (44%), Positives = 17/38 (44%), Gaps = 2/38 (5%)
Query: 187 PQTLQPQPPQPQPDPPPVPPGPTPV--PTGLLEPEPGG 222
P P PP P PP P GP P P GL P P G
Sbjct: 698 PPPPPPPPPLPNSPAPPNPGGPPPAPPPPGLAPPPPPG 735
Score = 32.0 bits (71), Expect = 2.6
Identities = 24/88 (27%), Positives = 30/88 (34%), Gaps = 18/88 (20%)
Query: 25 SQRPPAIPPMPPGILP--------------PMLPPMGAPPPLTQIPGMVPPMMP----GM 66
S + A+PP P I P P +PP+ A PPL P PP+ P G
Sbjct: 639 SNQQKALPPPPASIPPPPPLPSGLGSLSPAPPMPPVSAGPPLPPPPPPPPPLPPPSSAGP 698
Query: 67 LMPAVPVTAATAPGADTASSAVAGTGPP 94
P P +P PP
Sbjct: 699 PPPPPPPPLPNSPAPPNPGGPPPAPPPP 726
Score = 31.2 bits (69), Expect = 4.4
Identities = 21/61 (34%), Positives = 23/61 (37%), Gaps = 4/61 (6%)
Query: 178 AAGKQQQQLPQTLQPQPPQPQP-DPPPVPPGP---TPVPTGLLEPEPGGSEDCDVLEATQ 233
+AG P L P P P PPP PP P P P GL S C A +
Sbjct: 695 SAGPPPPPPPPPLPNSPAPPNPGGPPPAPPPPGLAPPPPPGLFFGLGSSSSQCPRKPAIE 754
Query: 234 P 234
P
Sbjct: 755 P 755
>gi|160707881 formin 2 [Homo sapiens]
Length = 1722
Score = 60.8 bits (146), Expect = 5e-09
Identities = 44/104 (42%), Positives = 53/104 (50%), Gaps = 13/104 (12%)
Query: 3 PPPFMPPPGIPPP--FPPMGLPPMSQRPPA-IPPMPP----GI-LPPMLPPMGAPPPLTQ 54
PPP +P GIPPP P +G+PP P A IPP PP GI PP LP +G PPP
Sbjct: 1131 PPPPLPGAGIPPPPPLPRVGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGVGIPPP-PP 1189
Query: 55 IPGM---VPPMMPGM-LMPAVPVTAATAPGADTASSAVAGTGPP 94
+PG+ PP +PG + P P+ P A GTG P
Sbjct: 1190 LPGVGIPPPPPLPGAGIPPPPPLPGMGIPPAPAPPLPPPGTGIP 1233
Score = 57.0 bits (136), Expect = 7e-08
Identities = 43/100 (43%), Positives = 53/100 (53%), Gaps = 17/100 (17%)
Query: 3 PPPFMPPPGIPPP--FPPMGLPPMSQRPPA-IPPMPP----GILPPMLPPMGAPPPLTQI 55
PPP +P GIPPP P +G+PP P A IPP PP GI P PP+ PPP T I
Sbjct: 1175 PPPPLPGVGIPPPPPLPGVGIPPPPPLPGAGIPPPPPLPGMGIPPAPAPPL--PPPGTGI 1232
Query: 56 PGMVPPMMPGMLMPAVP-VTAATAPGADTASSAVAGTGPP 94
P PP++P P +P V ++T P + V G PP
Sbjct: 1233 P--PPPLLPVSGPPLLPQVGSSTLP-----TPQVCGFLPP 1265
Score = 57.0 bits (136), Expect = 7e-08
Identities = 53/160 (33%), Positives = 70/160 (43%), Gaps = 25/160 (15%)
Query: 3 PPPFMPPPGI--PPPFPPMGLPPMSQRPPAIPPMPPGILPPMLPPMGAPPPLTQIPG--M 58
PPP +P GI PPP P MG+PP P +PP GI PP L P+ PP L Q+ +
Sbjct: 1197 PPPPLPGAGIPPPPPLPGMGIPPAP--APPLPPPGTGIPPPPLLPVSGPPLLPQVGSSTL 1254
Query: 59 VPPMMPGMLMPAVPVTAATAPGADTASSAVAGTGPPRAL----WSEHVAPDGRIYYYNAD 114
P + G L P +P S P R + W+ RI ++
Sbjct: 1255 PTPQVCGFLPPPLPSGLFGLGMNQDKGSRKQPIEPCRPMKPLYWT-------RIQLHSKR 1307
Query: 115 DKQS--VWEK---PSVLKSKAELLLSQCPWKEYK---SDT 146
D + +WEK PS+ + E L S+ KE K SDT
Sbjct: 1308 DSSTSLIWEKIEEPSIDCHEFEELFSKTAVKERKKPISDT 1347
Score = 56.6 bits (135), Expect = 1e-07
Identities = 43/104 (41%), Positives = 50/104 (48%), Gaps = 13/104 (12%)
Query: 3 PPPFMPPPGIPPP--FPPMGLPPMSQRPPA-IPPMPP----GI-LPPMLPPMGAPPPLTQ 54
PPP +P GIPPP P G+PP P A IPP PP GI PP LP G PPP
Sbjct: 1043 PPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPP-PP 1101
Query: 55 IPGM---VPPMMPGM-LMPAVPVTAATAPGADTASSAVAGTGPP 94
+PG+ PP +PG + P P+ A P A PP
Sbjct: 1102 LPGVGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPP 1145
Score = 56.6 bits (135), Expect = 1e-07
Identities = 33/80 (41%), Positives = 42/80 (52%), Gaps = 10/80 (12%)
Query: 3 PPPFMPPPGIPPP--FPPMGLPPMSQRP----PAIPPMPPGILPPMLPPMGA----PPPL 52
PPP +P GIPPP P +G+PP P P PP+P +PP P GA PPPL
Sbjct: 1087 PPPPLPGAGIPPPPPLPGVGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPL 1146
Query: 53 TQIPGMVPPMMPGMLMPAVP 72
++ PP +PG +P P
Sbjct: 1147 PRVGIPPPPPLPGAGIPPPP 1166
Score = 54.3 bits (129), Expect = 5e-07
Identities = 46/115 (40%), Positives = 54/115 (46%), Gaps = 16/115 (13%)
Query: 2 MPPPFMPPPGIPPP--FPPMGLPPMSQRPPA-IPPMPP----GI-LPPMLPPMGAPPPLT 53
+PPP +P GIPPP P G+PP P A IPP PP GI PP LP G PPP
Sbjct: 966 LPPP-LPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPP-P 1023
Query: 54 QIPGM---VPPMMPGM-LMPAVPVTAATAPGADTASSAVAGTGPPRALWSEHVAP 104
+PG PP +PG + P P+ A P AG PP L + P
Sbjct: 1024 PLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPG--AGIPPPPPLPGAGIPP 1076
Score = 49.7 bits (117), Expect = 1e-05
Identities = 47/130 (36%), Positives = 53/130 (40%), Gaps = 31/130 (23%)
Query: 1 MMPPPFMPPPG----------IPPPFPPMGLPPMSQRPP-----AIPPMPP----GILP- 40
M+PPP P PG IP P P G + PP IPP PP GILP
Sbjct: 875 MVPPPPPPLPGMTVPTLPSTAIPQPPPLQGTEMLPPPPPPLPGAGIPPPPPLPGAGILPL 934
Query: 41 PMLPPMGAPPPLTQIPGMV---PPMMPGMLMPAVPVTAATAPGADTASSAV---AGTGPP 94
P LP G PPP +PG PP +PG +P P PGA AG PP
Sbjct: 935 PPLPGAGIPPP-PPLPGAAIPPPPPLPGAGIPLPP----PLPGAGIPPPPPLPGAGIPPP 989
Query: 95 RALWSEHVAP 104
L + P
Sbjct: 990 PPLPGAGIPP 999
Score = 48.1 bits (113), Expect = 3e-05
Identities = 45/114 (39%), Positives = 52/114 (45%), Gaps = 15/114 (13%)
Query: 3 PPPFMPPPGIPPPFP-P-MGLPPMSQRPPA-IPPMPP----GI-LPPMLPPMGAPPPLTQ 54
PPP +P IPPP P P G+P P A IPP PP GI PP LP G PPP
Sbjct: 944 PPPPLPGAAIPPPPPLPGAGIPLPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPP-PP 1002
Query: 55 IPGM---VPPMMPGM-LMPAVPVTAATAPGADTASSAVAGTGPPRALWSEHVAP 104
+PG PP +PG + P P+ A P AG PP L + P
Sbjct: 1003 LPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPG--AGIPPPPPLPGAGIPP 1054
Score = 47.4 bits (111), Expect = 6e-05
Identities = 38/92 (41%), Positives = 44/92 (47%), Gaps = 23/92 (25%)
Query: 3 PPPFMPPPGIP-------------PPFPPMGLPPMSQRPPA-IPPMPP----GI-LPPML 43
PPP +P GIP PP P G+PP P A IPP PP GI PP L
Sbjct: 1098 PPPPLPGVGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPRVGIPPPPPL 1157
Query: 44 PPMGAPPPLTQIPGM---VPPMMPGMLMPAVP 72
P G PPP +PG PP +PG+ +P P
Sbjct: 1158 PGAGIPPP-PPLPGAGIPPPPPLPGVGIPPPP 1188
Score = 47.0 bits (110), Expect = 8e-05
Identities = 38/92 (41%), Positives = 43/92 (46%), Gaps = 23/92 (25%)
Query: 3 PPPFMPPPGIP-------------PPFPPMGLPPMSQRPPA-IPPMPP----GI-LPPML 43
PPP +P GIP PP P G+PP P A IPP PP GI PP L
Sbjct: 1010 PPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPL 1069
Query: 44 PPMGAPPPLTQIPGM---VPPMMPGMLMPAVP 72
P G PPP +PG PP +PG +P P
Sbjct: 1070 PGAGIPPP-PPLPGAGIPPPPPLPGAGIPPPP 1100
Score = 40.4 bits (93), Expect = 0.007
Identities = 30/101 (29%), Positives = 39/101 (38%), Gaps = 19/101 (18%)
Query: 13 PPPFP----PMGLPPMSQRPPAIPPMP-------PGILPPMLPPMGA----PPPLTQIPG 57
PPP P +P + PP PP+P P P PP+ PPP +PG
Sbjct: 858 PPPLPCTESSSSMPGLGMVPPPPPPLPGMTVPTLPSTAIPQPPPLQGTEMLPPPPPPLPG 917
Query: 58 M---VPPMMPGM-LMPAVPVTAATAPGADTASSAVAGTGPP 94
PP +PG ++P P+ A P A PP
Sbjct: 918 AGIPPPPPLPGAGILPLPPLPGAGIPPPPPLPGAAIPPPPP 958
Score = 32.3 bits (72), Expect = 2.0
Identities = 19/45 (42%), Positives = 22/45 (48%), Gaps = 10/45 (22%)
Query: 186 LPQTLQPQPPQPQ------PDPPPVP----PGPTPVPTGLLEPEP 220
LP T PQPP Q P PPP+P P P P+P + P P
Sbjct: 891 LPSTAIPQPPPLQGTEMLPPPPPPLPGAGIPPPPPLPGAGILPLP 935
Score = 30.4 bits (67), Expect = 7.4
Identities = 15/38 (39%), Positives = 20/38 (52%), Gaps = 7/38 (18%)
Query: 190 LQPQPPQPQ---PDPPPVP----PGPTPVPTGLLEPEP 220
+ P PP P+ P PPP+P P P P+P + P P
Sbjct: 1140 IPPPPPLPRVGIPPPPPLPGAGIPPPPPLPGAGIPPPP 1177
>gi|119395760 diaphanous 1 isoform 2 [Homo sapiens]
Length = 1263
Score = 60.5 bits (145), Expect = 7e-09
Identities = 48/143 (33%), Positives = 58/143 (40%), Gaps = 29/143 (20%)
Query: 3 PPPFMPPPGIPPPFPPMGLPPMSQRPPAIPPMPPGILPPMLPPMGAPPPLTQIPGMVPPM 62
PPP GIPPP PP LP + PP PP+P G P +PP PPP PG +PP
Sbjct: 682 PPPLPGSAGIPPPPPP--LPGEAGMPPPPPPLPGG---PGIPP---PPPFPGGPG-IPPP 732
Query: 63 MPGMLMPAVPVTAATAPGADTASSAVAGTGPPRALWSEHVAPDGRIYYYNADDKQSVWEK 122
PGM MP P P A + P+ L+ V +
Sbjct: 733 PPGMGMPPPPPFGFGVPAAPVLPFGLT----PKKLYKPEVQ----------------LRR 772
Query: 123 PSVLKSKAELLLSQCPWKEYKSD 145
P+ K AE L C W + K D
Sbjct: 773 PNWSKLVAEDLSQDCFWTKVKED 795
Score = 47.0 bits (110), Expect = 8e-05
Identities = 31/77 (40%), Positives = 38/77 (49%), Gaps = 16/77 (20%)
Query: 2 MPPPFMPPP---GIPPPFPPM----GLPPMSQRP--PAIPPMPPGILPPMLPPMGAPPPL 52
+PPP P P G+PPP PP+ G+PP P P IPP PPG+ P PP G P
Sbjct: 691 IPPPPPPLPGEAGMPPPPPPLPGGPGIPPPPPFPGGPGIPPPPPGMGMPPPPPFGFGVP- 749
Query: 53 TQIPGMVPPMMPGMLMP 69
P++P L P
Sbjct: 750 ------AAPVLPFGLTP 760
Score = 43.5 bits (101), Expect = 9e-04
Identities = 39/116 (33%), Positives = 51/116 (43%), Gaps = 20/116 (17%)
Query: 1 MMPPPFMPPPGIPPPFPPMGLPPMSQRPPAIPPMPPGIL---PPMLP---PMGAPPPLT- 53
++PPP P PP PP PP PP PP+P G+ PP LP + PPPL+
Sbjct: 586 IIPPPPAPGDSTTPPPPP---PP----PPPPPPLPGGVCISSPPSLPGGTAISPPPPLSG 638
Query: 54 --QIPGMVPPMMPGMLMP---AVPVTAATAPGADTASSAVAGTGPPRALWSEHVAP 104
IP PP+ G+ +P ++P A P SA PP S + P
Sbjct: 639 DATIP-PPPPLPEGVGIPSPSSLPGGTAIPPPPPLPGSARIPPPPPPLPGSAGIPP 693
Score = 37.7 bits (86), Expect = 0.047
Identities = 37/114 (32%), Positives = 45/114 (39%), Gaps = 33/114 (28%)
Query: 4 PPFMPPPGIPPPFPPMG-------LPPMSQRPPAIPPMPPGILPPMLPPMGAPPPLTQIP 56
PP +P PP PP+ PP + PP PP PP PPPL P
Sbjct: 564 PPSVPSRAPVPPAPPLPGDSGTIIPPPPAPGDSTTPPPPP-------PPPPPPPPL---P 613
Query: 57 GMV----PPMMPG--MLMPAVPVTA-ATAP---------GADTASSAVAGTGPP 94
G V PP +PG + P P++ AT P G + SS GT P
Sbjct: 614 GGVCISSPPSLPGGTAISPPPPLSGDATIPPPPPLPEGVGIPSPSSLPGGTAIP 667
Score = 34.7 bits (78), Expect = 0.39
Identities = 16/37 (43%), Positives = 19/37 (51%), Gaps = 5/37 (13%)
Query: 189 TLQPQPPQP-----QPDPPPVPPGPTPVPTGLLEPEP 220
T+ P PP P P PPP PP P P+P G+ P
Sbjct: 585 TIIPPPPAPGDSTTPPPPPPPPPPPPPLPGGVCISSP 621
Score = 31.6 bits (70), Expect = 3.3
Identities = 42/193 (21%), Positives = 76/193 (39%), Gaps = 42/193 (21%)
Query: 334 EEKEEARLRAKEAKQTLQHFLEQHERMTSTTRYRRAEQTFGELEVWAVVPERDRKEVYDD 393
+E ++ + + LQ L+Q ++ S E +V D K+ + +
Sbjct: 1030 DELAHVEKASRVSAENLQKNLDQMKKQISDV----------ERDVQNFPAATDEKDKFVE 1079
Query: 394 VLFFLAKKEKEQAKQLRRRNIQALKSILDGMSSVNFQTTWSQAQQYLMDNPS-------F 446
+ K +EQ +LR M N +T + + +Y + +P F
Sbjct: 1080 KMTSFVKDAQEQYNKLR-------------MMHSNMETLYKELGEYFLFDPKKLSVEEFF 1126
Query: 447 AQDHQLQNMDKEDALICFEEHIRALEREEEEERERARL------RERRQQRKNREAFQTF 500
H +NM L +E+ + RE EE+ RA+L +ER ++++ RE
Sbjct: 1127 MDLHNFRNM----FLQAVKENQK--RRETEEKMRRAKLAKEKAEKERLEKQQKREQLIDM 1180
Query: 501 LDELHETGQLHSM 513
E ETG + S+
Sbjct: 1181 NAEGDETGVMDSL 1193
Score = 30.4 bits (67), Expect = 7.4
Identities = 14/30 (46%), Positives = 15/30 (50%)
Query: 194 PPQPQPDPPPVPPGPTPVPTGLLEPEPGGS 223
PP P P PPP PP P V PGG+
Sbjct: 599 PPPPPPPPPPPPPLPGGVCISSPPSLPGGT 628
Score = 30.4 bits (67), Expect = 7.4
Identities = 13/29 (44%), Positives = 15/29 (51%)
Query: 192 PQPPQPQPDPPPVPPGPTPVPTGLLEPEP 220
P PP P P +PP P P+P G P P
Sbjct: 692 PPPPPPLPGEAGMPPPPPPLPGGPGIPPP 720
Score = 30.4 bits (67), Expect = 7.4
Identities = 41/170 (24%), Positives = 71/170 (41%), Gaps = 26/170 (15%)
Query: 192 PQPPQPQPDPPPVPPGPTPVP--TGLLEPEPGGSEDCDVLEATQPLEQGFLQQLEEGPSS 249
P PP P P P +PP P P P G+ P PG + P GF P++
Sbjct: 705 PPPPPPLPGGPGIPP-PPPFPGGPGIPPPPPG-------MGMPPPPPFGF-----GVPAA 751
Query: 250 SGQHQPQQEEEESKPEPERSGLSWSN---REKAKQAFKELLRDKAVPSNASWEQAMKMVV 306
++ KPE + +WS + ++ F +++ +N E K+ +
Sbjct: 752 PVLPFGLTPKKLYKPEVQLRRPNWSKLVAEDLSQDCFWTKVKEDRFENN---ELFAKLTL 808
Query: 307 TDPRYSALPKLSEKKQAFNAYKAQREKEEKEEARLRAKEAK--QTLQHFL 354
T +SA K S+ K+ + ++ ++K+ L+ ++K Q L FL
Sbjct: 809 T---FSAQTKTSKAKKDQEGGEEKKSVQKKKVKELKVLDSKTAQNLSIFL 855
Score = 30.0 bits (66), Expect = 9.7
Identities = 13/31 (41%), Positives = 16/31 (51%), Gaps = 2/31 (6%)
Query: 192 PQPPQPQPDPPPVPPGPTPVP--TGLLEPEP 220
P PP P P +PP P P+P G+ P P
Sbjct: 679 PPPPPPLPGSAGIPPPPPPLPGEAGMPPPPP 709
>gi|119395758 diaphanous 1 isoform 1 [Homo sapiens]
Length = 1272
Score = 60.5 bits (145), Expect = 7e-09
Identities = 48/143 (33%), Positives = 58/143 (40%), Gaps = 29/143 (20%)
Query: 3 PPPFMPPPGIPPPFPPMGLPPMSQRPPAIPPMPPGILPPMLPPMGAPPPLTQIPGMVPPM 62
PPP GIPPP PP LP + PP PP+P G P +PP PPP PG +PP
Sbjct: 691 PPPLPGSAGIPPPPPP--LPGEAGMPPPPPPLPGG---PGIPP---PPPFPGGPG-IPPP 741
Query: 63 MPGMLMPAVPVTAATAPGADTASSAVAGTGPPRALWSEHVAPDGRIYYYNADDKQSVWEK 122
PGM MP P P A + P+ L+ V +
Sbjct: 742 PPGMGMPPPPPFGFGVPAAPVLPFGLT----PKKLYKPEVQ----------------LRR 781
Query: 123 PSVLKSKAELLLSQCPWKEYKSD 145
P+ K AE L C W + K D
Sbjct: 782 PNWSKLVAEDLSQDCFWTKVKED 804
Score = 47.0 bits (110), Expect = 8e-05
Identities = 31/77 (40%), Positives = 38/77 (49%), Gaps = 16/77 (20%)
Query: 2 MPPPFMPPP---GIPPPFPPM----GLPPMSQRP--PAIPPMPPGILPPMLPPMGAPPPL 52
+PPP P P G+PPP PP+ G+PP P P IPP PPG+ P PP G P
Sbjct: 700 IPPPPPPLPGEAGMPPPPPPLPGGPGIPPPPPFPGGPGIPPPPPGMGMPPPPPFGFGVP- 758
Query: 53 TQIPGMVPPMMPGMLMP 69
P++P L P
Sbjct: 759 ------AAPVLPFGLTP 769
Score = 43.5 bits (101), Expect = 9e-04
Identities = 39/116 (33%), Positives = 51/116 (43%), Gaps = 20/116 (17%)
Query: 1 MMPPPFMPPPGIPPPFPPMGLPPMSQRPPAIPPMPPGIL---PPMLP---PMGAPPPLT- 53
++PPP P PP PP PP PP PP+P G+ PP LP + PPPL+
Sbjct: 595 IIPPPPAPGDSTTPPPPP---PP----PPPPPPLPGGVCISSPPSLPGGTAISPPPPLSG 647
Query: 54 --QIPGMVPPMMPGMLMP---AVPVTAATAPGADTASSAVAGTGPPRALWSEHVAP 104
IP PP+ G+ +P ++P A P SA PP S + P
Sbjct: 648 DATIP-PPPPLPEGVGIPSPSSLPGGTAIPPPPPLPGSARIPPPPPPLPGSAGIPP 702
Score = 37.7 bits (86), Expect = 0.047
Identities = 37/114 (32%), Positives = 45/114 (39%), Gaps = 33/114 (28%)
Query: 4 PPFMPPPGIPPPFPPMG-------LPPMSQRPPAIPPMPPGILPPMLPPMGAPPPLTQIP 56
PP +P PP PP+ PP + PP PP PP PPPL P
Sbjct: 573 PPSVPSRAPVPPAPPLPGDSGTIIPPPPAPGDSTTPPPPP-------PPPPPPPPL---P 622
Query: 57 GMV----PPMMPG--MLMPAVPVTA-ATAP---------GADTASSAVAGTGPP 94
G V PP +PG + P P++ AT P G + SS GT P
Sbjct: 623 GGVCISSPPSLPGGTAISPPPPLSGDATIPPPPPLPEGVGIPSPSSLPGGTAIP 676
Score = 34.7 bits (78), Expect = 0.39
Identities = 16/37 (43%), Positives = 19/37 (51%), Gaps = 5/37 (13%)
Query: 189 TLQPQPPQP-----QPDPPPVPPGPTPVPTGLLEPEP 220
T+ P PP P P PPP PP P P+P G+ P
Sbjct: 594 TIIPPPPAPGDSTTPPPPPPPPPPPPPLPGGVCISSP 630
Score = 31.6 bits (70), Expect = 3.3
Identities = 42/193 (21%), Positives = 76/193 (39%), Gaps = 42/193 (21%)
Query: 334 EEKEEARLRAKEAKQTLQHFLEQHERMTSTTRYRRAEQTFGELEVWAVVPERDRKEVYDD 393
+E ++ + + LQ L+Q ++ S E +V D K+ + +
Sbjct: 1039 DELAHVEKASRVSAENLQKNLDQMKKQISDV----------ERDVQNFPAATDEKDKFVE 1088
Query: 394 VLFFLAKKEKEQAKQLRRRNIQALKSILDGMSSVNFQTTWSQAQQYLMDNPS-------F 446
+ K +EQ +LR M N +T + + +Y + +P F
Sbjct: 1089 KMTSFVKDAQEQYNKLR-------------MMHSNMETLYKELGEYFLFDPKKLSVEEFF 1135
Query: 447 AQDHQLQNMDKEDALICFEEHIRALEREEEEERERARL------RERRQQRKNREAFQTF 500
H +NM L +E+ + RE EE+ RA+L +ER ++++ RE
Sbjct: 1136 MDLHNFRNM----FLQAVKENQK--RRETEEKMRRAKLAKEKAEKERLEKQQKREQLIDM 1189
Query: 501 LDELHETGQLHSM 513
E ETG + S+
Sbjct: 1190 NAEGDETGVMDSL 1202
Score = 30.4 bits (67), Expect = 7.4
Identities = 14/30 (46%), Positives = 15/30 (50%)
Query: 194 PPQPQPDPPPVPPGPTPVPTGLLEPEPGGS 223
PP P P PPP PP P V PGG+
Sbjct: 608 PPPPPPPPPPPPPLPGGVCISSPPSLPGGT 637
Score = 30.4 bits (67), Expect = 7.4
Identities = 13/29 (44%), Positives = 15/29 (51%)
Query: 192 PQPPQPQPDPPPVPPGPTPVPTGLLEPEP 220
P PP P P +PP P P+P G P P
Sbjct: 701 PPPPPPLPGEAGMPPPPPPLPGGPGIPPP 729
Score = 30.4 bits (67), Expect = 7.4
Identities = 41/170 (24%), Positives = 71/170 (41%), Gaps = 26/170 (15%)
Query: 192 PQPPQPQPDPPPVPPGPTPVP--TGLLEPEPGGSEDCDVLEATQPLEQGFLQQLEEGPSS 249
P PP P P P +PP P P P G+ P PG + P GF P++
Sbjct: 714 PPPPPPLPGGPGIPP-PPPFPGGPGIPPPPPG-------MGMPPPPPFGF-----GVPAA 760
Query: 250 SGQHQPQQEEEESKPEPERSGLSWSN---REKAKQAFKELLRDKAVPSNASWEQAMKMVV 306
++ KPE + +WS + ++ F +++ +N E K+ +
Sbjct: 761 PVLPFGLTPKKLYKPEVQLRRPNWSKLVAEDLSQDCFWTKVKEDRFENN---ELFAKLTL 817
Query: 307 TDPRYSALPKLSEKKQAFNAYKAQREKEEKEEARLRAKEAK--QTLQHFL 354
T +SA K S+ K+ + ++ ++K+ L+ ++K Q L FL
Sbjct: 818 T---FSAQTKTSKAKKDQEGGEEKKSVQKKKVKELKVLDSKTAQNLSIFL 864
Score = 30.0 bits (66), Expect = 9.7
Identities = 13/31 (41%), Positives = 16/31 (51%), Gaps = 2/31 (6%)
Query: 192 PQPPQPQPDPPPVPPGPTPVP--TGLLEPEP 220
P PP P P +PP P P+P G+ P P
Sbjct: 688 PPPPPPLPGSAGIPPPPPPLPGEAGMPPPPP 718
>gi|162329583 cleavage and polyadenylation specific factor 6, 68 kD
subunit [Homo sapiens]
Length = 551
Score = 60.5 bits (145), Expect = 7e-09
Identities = 40/90 (44%), Positives = 44/90 (48%), Gaps = 17/90 (18%)
Query: 1 MMPPPFMPPPGI----PPP--FP--PMGLPPMSQRPPAIPPMPPGILPPMLPP---MGAP 49
++PPP PP PPP FP P G PP+ PP PP PG PP PP G P
Sbjct: 258 VLPPPLAGPPNRGDRPPPPVLFPGQPFGQPPLGPLPPGPPPPVPGYGPPPGPPPPQQGPP 317
Query: 50 PPLTQIPGMVPPMMPGMLMPAVPVTAATAP 79
PP PG PP PG L P P+T A P
Sbjct: 318 PP----PGPFPPRPPGPLGP--PLTLAPPP 341
Score = 56.6 bits (135), Expect = 1e-07
Identities = 39/97 (40%), Positives = 42/97 (43%), Gaps = 10/97 (10%)
Query: 4 PPFMP-PPGIPPPFPPMGLPPMSQRPPAIPPMPPGILPPMLPPMGAPPPLTQIPGMVPPM 62
PP P PPG PPP P G PP P PP PPG PP PP PPLT P PP
Sbjct: 287 PPLGPLPPGPPPPVPGYGPPPGPPPPQQGPPPPPGPFPPR-PPGPLGPPLTLAP---PPH 342
Query: 63 MPGMLMPAVPVT-----AATAPGADTASSAVAGTGPP 94
+PG A P A P ++ GPP
Sbjct: 343 LPGPPPGAPPPAPHVNPAFFPPPTNSGMPTSDSRGPP 379
Score = 52.8 bits (125), Expect = 1e-06
Identities = 32/74 (43%), Positives = 34/74 (45%), Gaps = 15/74 (20%)
Query: 3 PPPFMPPPGIPPPFPPMGLPPMSQRPP----AIPPMPPGILPPML----------PPMGA 48
P P PPP +P PP G PP Q PP PP PPG L P L PP GA
Sbjct: 291 PLPPGPPPPVPGYGPPPGPPPPQQGPPPPPGPFPPRPPGPLGPPLTLAPPPHLPGPPPGA 350
Query: 49 PPPLTQI-PGMVPP 61
PPP + P PP
Sbjct: 351 PPPAPHVNPAFFPP 364
Score = 51.6 bits (122), Expect = 3e-06
Identities = 37/89 (41%), Positives = 38/89 (42%), Gaps = 8/89 (8%)
Query: 9 PPGIPPPFPPMGLPPMSQRPPAIPPMPPGILPPMLPPMG--APPPLTQIPGMVPPMMPGM 66
P G PPPFP PP RPP PP PPG PP PP G PPPL P P +
Sbjct: 223 PGGPPPPFPAGQTPP---RPPLGPPGPPG--PPGPPPPGQVLPPPLAGPPNRGDRPPPPV 277
Query: 67 LMPAVPV-TAATAPGADTASSAVAGTGPP 94
L P P P V G GPP
Sbjct: 278 LFPGQPFGQPPLGPLPPGPPPPVPGYGPP 306
Score = 48.5 bits (114), Expect = 3e-05
Identities = 36/94 (38%), Positives = 41/94 (43%), Gaps = 21/94 (22%)
Query: 3 PPPFMPPPGIPPPFPPMGLPPMSQRPPAIPPMPPGILPPML-----------PPMGAP-- 49
PPPF P G PP PP+G PP PP PP P +LPP L PP+ P
Sbjct: 227 PPPF--PAGQTPPRPPLG-PPGPPGPPG-PPPPGQVLPPPLAGPPNRGDRPPPPVLFPGQ 282
Query: 50 ----PPLTQIPGMVPPMMPGMLMPAVPVTAATAP 79
PPL +P PP +PG P P P
Sbjct: 283 PFGQPPLGPLPPGPPPPVPGYGPPPGPPPPQQGP 316
Score = 39.3 bits (90), Expect = 0.016
Identities = 23/55 (41%), Positives = 26/55 (47%), Gaps = 6/55 (10%)
Query: 1 MMPPPFM--PPPGIPPPFPPMGLPPMSQRPPAIPPMPPGIL--PPMLPPMGAPPP 51
+ PPP + PPPG PPP P + P PP MP PP P G PPP
Sbjct: 337 LAPPPHLPGPPPGAPPPAPHVN--PAFFPPPTNSGMPTSDSRGPPPTDPYGRPPP 389
Score = 32.7 bits (73), Expect = 1.5
Identities = 17/28 (60%), Positives = 17/28 (60%), Gaps = 2/28 (7%)
Query: 192 PQPPQPQPDPPPVPPGP-TPVPTGLLEP 218
P PP PQ PPP PPGP P P G L P
Sbjct: 307 PGPPPPQQGPPP-PPGPFPPRPPGPLGP 333
Score = 31.6 bits (70), Expect = 3.3
Identities = 26/81 (32%), Positives = 28/81 (34%), Gaps = 23/81 (28%)
Query: 3 PPPFMPPPGIPPPFPP-----------------MGLPPMSQRPPAIPPMPPGILPP---- 41
PPP PP P PFPP + PP PPA P + P PP
Sbjct: 310 PPPQQGPPPPPGPFPPRPPGPLGPPLTLAPPPHLPGPPPGAPPPA-PHVNPAFFPPPTNS 368
Query: 42 -MLPPMGAPPPLTQIPGMVPP 61
M PP T G PP
Sbjct: 369 GMPTSDSRGPPPTDPYGRPPP 389
Score = 31.6 bits (70), Expect = 3.3
Identities = 28/117 (23%), Positives = 43/117 (36%), Gaps = 7/117 (5%)
Query: 187 PQTLQPQPPQPQPDPPPVPPGP---TPVPTGLLEPEPGGSEDCDVLEAT---QPLEQGFL 240
PQ P PP P P PP P GP P L P PG + P G
Sbjct: 312 PQQGPPPPPGPFPPRPPGPLGPPLTLAPPPHLPGPPPGAPPPAPHVNPAFFPPPTNSGMP 371
Query: 241 QQLEEGPSSSGQHQPQQEEEESKPEPERSGLSWSNREKAKQAFKELL-RDKAVPSNA 296
GP + + + P + + ++ F+E++ R++A+ S+A
Sbjct: 372 TSDSRGPPPTDPYGRPPPYDRGDYGPPGREMDTARTPLSEAEFEEIMNRNRAISSSA 428
Score = 31.2 bits (69), Expect = 4.4
Identities = 25/62 (40%), Positives = 27/62 (43%), Gaps = 9/62 (14%)
Query: 194 PPQPQPDPPPVPPGPT-PVPTGLLEPEP-------GGSEDCDVLEATQPLEQGFLQQLEE 245
PP+P P PP PPGP P P G + P P G VL QP Q L L
Sbjct: 236 PPRP-PLGPPGPPGPPGPPPPGQVLPPPLAGPPNRGDRPPPPVLFPGQPFGQPPLGPLPP 294
Query: 246 GP 247
GP
Sbjct: 295 GP 296
Score = 31.2 bits (69), Expect = 4.4
Identities = 23/100 (23%), Positives = 48/100 (48%), Gaps = 5/100 (5%)
Query: 398 LAKKEKEQAKQLRRRNIQALKSILDGMSSVNFQTTWSQAQQYLMDNPSFAQD---HQLQN 454
L K+ K A + I +L+ L G+ S ++ + + + D+ + H+ ++
Sbjct: 454 LIKQSKVSADDRCKVLISSLQDCLHGIESKSYGSGSRRERSRERDHSRSREKSRRHKSRS 513
Query: 455 MDKEDALICFEEHIRALEREEEEERERARLRERRQQRKNR 494
D+ D + E R ER + +R+R R R+R ++ ++R
Sbjct: 514 RDRHDDY--YRERSRERERHRDRDRDRDRERDREREYRHR 551
Score = 30.8 bits (68), Expect = 5.7
Identities = 18/41 (43%), Positives = 18/41 (43%), Gaps = 8/41 (19%)
Query: 190 LQPQPPQPQP-----DPPPVPPGP---TPVPTGLLEPEPGG 222
L P PP P P PPP PP P P P G P P G
Sbjct: 289 LGPLPPGPPPPVPGYGPPPGPPPPQQGPPPPPGPFPPRPPG 329
>gi|239754327 PREDICTED: chromosome 6 open reading frame 132 [Homo
sapiens]
Length = 1188
Score = 60.1 bits (144), Expect = 9e-09
Identities = 78/288 (27%), Positives = 100/288 (34%), Gaps = 60/288 (20%)
Query: 3 PPPFMPPPGIPPPFP-PMGLPPMSQRPPAIPPMPPGILPPMLPPMGAPPP---------- 51
PPP P PG P P G P+ P PP PP +L P PP APPP
Sbjct: 141 PPPPGPAPGPPQDISEPPGGSPLPSPPSTAPPPPPLLLEPPPPPSMAPPPPPVLEALSPP 200
Query: 52 -------LTQIPGMVPPMMP-GMLMPAVPVTAATAPGADTASSAVAGTG--PPRAL--WS 99
+ P +PP P L P P A AP A AS GT PP + W
Sbjct: 201 HTLSSPSIPTPPDFIPPAPPLAFLAPPPPPVPAPAPPA-PASPHTVGTRLFPPGGVTKWK 259
Query: 100 EHVAPDGRIYYYNADDKQSVWEKPSVLKSKAELLLSQCPWKEYKSDTGKPYYYNNQSKES 159
VA +GR Q+ + S +S AE P +P+ +S +
Sbjct: 260 SDVALNGR---------QAEATRASPPRSPAE------PKGSALGPNPEPHLTFPRSFKV 304
Query: 160 RWTRPKDLDDLEVLVKQEAAGKQQQQLPQTLQPQPPQPQPDPPPVPPGPTPVPTGLLEPE 219
P + V QEA K++ + P P+PP P + P+
Sbjct: 305 PPPTPVRTSSIPVQEAQEAPRKEEGATKKA---------PSRLPLPPSFHIRPASQVYPD 355
Query: 220 PGGSEDC-DVLEATQPLEQGFLQQLEEGPSSSGQHQPQQEEEESKPEP 266
DC L+AT P GQ Q Q +E P P
Sbjct: 356 RAPEPDCPGELKATAPASPRL-----------GQSQSQADERAGTPPP 392
Score = 43.1 bits (100), Expect = 0.001
Identities = 27/72 (37%), Positives = 34/72 (47%), Gaps = 4/72 (5%)
Query: 11 GIPPPFPPMGLPPMSQRPPAIPPMPPGILPPMLPPMGAPPP--LTQIP-GMVPPMMPGML 67
G PPP PP+ PP PP PP+PP P A PP T+ P P + P
Sbjct: 388 GTPPPAPPLP-PPAPPLPPPAPPLPPAAPPLPCAQKAAHPPAGFTKTPKSSSPALKPKPN 446
Query: 68 MPAVPVTAATAP 79
P+ TA++AP
Sbjct: 447 PPSPENTASSAP 458
Score = 35.8 bits (81), Expect = 0.18
Identities = 28/95 (29%), Positives = 33/95 (34%), Gaps = 10/95 (10%)
Query: 9 PPGIPPPFPPMGLPPMSQRPPAIPPM--------PPGILPPMLPPMGAPPPLTQIPGMVP 60
PP P L P + PAIPP P L P PP P T +
Sbjct: 619 PPQSTTLLPTTSLQPKAMLGPAIPPKATPEPAIPPKATLWPATPPKATLGPATPLKATSG 678
Query: 61 PMMP--GMLMPAVPVTAATAPGADTASSAVAGTGP 93
P P PA+ TA T P + A +GP
Sbjct: 679 PTTPLKATSGPAIASTATTLPTTTSQLMAEKDSGP 713
Score = 35.0 bits (79), Expect = 0.30
Identities = 24/75 (32%), Positives = 29/75 (38%), Gaps = 8/75 (10%)
Query: 31 IPPMPPGILPPMLPPMGAPP---PLTQIPGMVPPMMPGMLMPAVPVTAATAPGADTASSA 87
IPP PPG P + PP PL P PP P +L P P + A P
Sbjct: 139 IPPPPPGPAPGPPQDISEPPGGSPLPSPPSTAPPPPPLLLEPPPPPSMAPPP-----PPV 193
Query: 88 VAGTGPPRALWSEHV 102
+ PP L S +
Sbjct: 194 LEALSPPHTLSSPSI 208
Score = 34.3 bits (77), Expect = 0.52
Identities = 63/283 (22%), Positives = 94/283 (33%), Gaps = 55/283 (19%)
Query: 4 PPFMPPPGIP-------PPFPPMGLPPMS--QRPPAIPPMPPGILPPMLPPMGAPPPLTQ 54
P P P P P P +G +R PP PP LPP PP+ PPP
Sbjct: 354 PDRAPEPDCPGELKATAPASPRLGQSQSQADERAGTPPPAPP--LPPPAPPL--PPPAPP 409
Query: 55 IPGMVPPMMPGMLMPAVPVTAATAPGADTASSAVAGTGPPRALWSEHVAPDGRIYYYNAD 114
+P PP +P A P T ++ + PP +P+ A
Sbjct: 410 LPPAAPP-LPCAQKAAHPPAGFTKTPKSSSPALKPKPNPP--------SPEN-----TAS 455
Query: 115 DKQSVWEKPSVLKSKAELLLSQCPWKEYKSDTGKPYYYNNQSKESRWT--RPKDLDDLEV 172
W PS ++ L + Y +E R+ RP
Sbjct: 456 SAPVDWRDPSQMEKLRNELAA---------------YLCGSRREDRFLSHRPG-----PT 495
Query: 173 LVKQEAAGKQQQQLPQTLQPQPPQPQPDPPPVPPGPTPVPTGLLEPEPG-----GSEDCD 227
+ Q GK+ +LP+ + P D PP P + + L E E S D
Sbjct: 496 VAPQSKEGKKGPRLPEK-ETLLSLPAKDTPPGVPEKSLGGSSLTETEAAPSLTLPSVDYI 554
Query: 228 VLEATQPLEQGFLQQLEEGPSSSGQHQPQQEEEESKPEPERSG 270
++ P + +LE SS+ + + + P+P G
Sbjct: 555 PQDSPTPSVRQIRNELEARLSSAAEKEAKPSIGSLPPKPRLEG 597
Score = 33.9 bits (76), Expect = 0.67
Identities = 63/268 (23%), Positives = 84/268 (31%), Gaps = 55/268 (20%)
Query: 2 MPPPFMPPPGIPPPFPPMGLP-PMSQR---PPAIPPMPPGILPPMLPPMGAPPP------ 51
+PPP P P PP PP P P +Q+ PPA P P L P PP
Sbjct: 396 LPPPAPPLPPPAPPLPPAAPPLPCAQKAAHPPAGFTKTPKSSSPALKPKPNPPSPENTAS 455
Query: 52 --------------------------------LTQIPG--MVPPMMPGMLMPAVP--VTA 75
L+ PG + P G P +P T
Sbjct: 456 SAPVDWRDPSQMEKLRNELAAYLCGSRREDRFLSHRPGPTVAPQSKEGKKGPRLPEKETL 515
Query: 76 ATAPGADTASSAVAGTGPPRALWSEHVAPDGRIYYYNADDKQSVWEKPSVLKSKAELLLS 135
+ P DT + +L AP + + + S ++++ E LS
Sbjct: 516 LSLPAKDTPPGVPEKSLGGSSLTETEAAPSLTLPSVDYIPQDSPTPSVRQIRNELEARLS 575
Query: 136 QCPWKEYKSDTG----KPYYYNNQSKESRWTRPKDLDDLEVLVKQEAAGKQQQQLPQT-L 190
KE K G KP + E+ D D L V + + LP T L
Sbjct: 576 SAAEKEAKPSIGSLPPKPRLEGGRICEN----GADDDKLSKPVAKNLPPQSTTLLPTTSL 631
Query: 191 QPQPPQPQPDPPPVPPGPTPVPTGLLEP 218
QP+ PP P P P L P
Sbjct: 632 QPKAMLGPAIPPKATPEPAIPPKATLWP 659
Score = 30.0 bits (66), Expect = 9.7
Identities = 12/22 (54%), Positives = 13/22 (59%)
Query: 202 PPVPPGPTPVPTGLLEPEPGGS 223
PP PPGP P P + PGGS
Sbjct: 140 PPPPPGPAPGPPQDISEPPGGS 161
>gi|239748855 PREDICTED: chromosome 6 open reading frame 132 [Homo
sapiens]
Length = 1188
Score = 60.1 bits (144), Expect = 9e-09
Identities = 78/288 (27%), Positives = 100/288 (34%), Gaps = 60/288 (20%)
Query: 3 PPPFMPPPGIPPPFP-PMGLPPMSQRPPAIPPMPPGILPPMLPPMGAPPP---------- 51
PPP P PG P P G P+ P PP PP +L P PP APPP
Sbjct: 141 PPPPGPAPGPPQDISEPPGGSPLPSPPSTAPPPPPLLLEPPPPPSMAPPPPPVLEALSPP 200
Query: 52 -------LTQIPGMVPPMMP-GMLMPAVPVTAATAPGADTASSAVAGTG--PPRAL--WS 99
+ P +PP P L P P A AP A AS GT PP + W
Sbjct: 201 HTLSSPSIPTPPDFIPPAPPLAFLAPPPPPVPAPAPPA-PASPHTVGTRLFPPGGVTKWK 259
Query: 100 EHVAPDGRIYYYNADDKQSVWEKPSVLKSKAELLLSQCPWKEYKSDTGKPYYYNNQSKES 159
VA +GR Q+ + S +S AE P +P+ +S +
Sbjct: 260 SDVALNGR---------QAEATRASPPRSPAE------PKGSALGPNPEPHLTFPRSFKV 304
Query: 160 RWTRPKDLDDLEVLVKQEAAGKQQQQLPQTLQPQPPQPQPDPPPVPPGPTPVPTGLLEPE 219
P + V QEA K++ + P P+PP P + P+
Sbjct: 305 PPPTPVRTSSIPVQEAQEAPRKEEGATKKA---------PSRLPLPPSFHIRPASQVYPD 355
Query: 220 PGGSEDC-DVLEATQPLEQGFLQQLEEGPSSSGQHQPQQEEEESKPEP 266
DC L+AT P GQ Q Q +E P P
Sbjct: 356 RAPEPDCPGELKATAPASPRL-----------GQSQSQADERAGTPPP 392
Score = 43.1 bits (100), Expect = 0.001
Identities = 27/72 (37%), Positives = 34/72 (47%), Gaps = 4/72 (5%)
Query: 11 GIPPPFPPMGLPPMSQRPPAIPPMPPGILPPMLPPMGAPPP--LTQIP-GMVPPMMPGML 67
G PPP PP+ PP PP PP+PP P A PP T+ P P + P
Sbjct: 388 GTPPPAPPLP-PPAPPLPPPAPPLPPAAPPLPCAQKAAHPPAGFTKTPKSSSPALKPKPN 446
Query: 68 MPAVPVTAATAP 79
P+ TA++AP
Sbjct: 447 PPSPENTASSAP 458
Score = 35.8 bits (81), Expect = 0.18
Identities = 28/95 (29%), Positives = 33/95 (34%), Gaps = 10/95 (10%)
Query: 9 PPGIPPPFPPMGLPPMSQRPPAIPPM--------PPGILPPMLPPMGAPPPLTQIPGMVP 60
PP P L P + PAIPP P L P PP P T +
Sbjct: 619 PPQSTTLLPTTSLQPKAMLGPAIPPKATPEPAIPPKATLWPATPPKATLGPATPLKATSG 678
Query: 61 PMMP--GMLMPAVPVTAATAPGADTASSAVAGTGP 93
P P PA+ TA T P + A +GP
Sbjct: 679 PTTPLKATSGPAIASTATTLPTTTSQLMAEKDSGP 713
Score = 35.0 bits (79), Expect = 0.30
Identities = 24/75 (32%), Positives = 29/75 (38%), Gaps = 8/75 (10%)
Query: 31 IPPMPPGILPPMLPPMGAPP---PLTQIPGMVPPMMPGMLMPAVPVTAATAPGADTASSA 87
IPP PPG P + PP PL P PP P +L P P + A P
Sbjct: 139 IPPPPPGPAPGPPQDISEPPGGSPLPSPPSTAPPPPPLLLEPPPPPSMAPPP-----PPV 193
Query: 88 VAGTGPPRALWSEHV 102
+ PP L S +
Sbjct: 194 LEALSPPHTLSSPSI 208
Score = 34.3 bits (77), Expect = 0.52
Identities = 63/283 (22%), Positives = 94/283 (33%), Gaps = 55/283 (19%)
Query: 4 PPFMPPPGIP-------PPFPPMGLPPMS--QRPPAIPPMPPGILPPMLPPMGAPPPLTQ 54
P P P P P P +G +R PP PP LPP PP+ PPP
Sbjct: 354 PDRAPEPDCPGELKATAPASPRLGQSQSQADERAGTPPPAPP--LPPPAPPL--PPPAPP 409
Query: 55 IPGMVPPMMPGMLMPAVPVTAATAPGADTASSAVAGTGPPRALWSEHVAPDGRIYYYNAD 114
+P PP +P A P T ++ + PP +P+ A
Sbjct: 410 LPPAAPP-LPCAQKAAHPPAGFTKTPKSSSPALKPKPNPP--------SPEN-----TAS 455
Query: 115 DKQSVWEKPSVLKSKAELLLSQCPWKEYKSDTGKPYYYNNQSKESRWT--RPKDLDDLEV 172
W PS ++ L + Y +E R+ RP
Sbjct: 456 SAPVDWRDPSQMEKLRNELAA---------------YLCGSRREDRFLSHRPG-----PT 495
Query: 173 LVKQEAAGKQQQQLPQTLQPQPPQPQPDPPPVPPGPTPVPTGLLEPEPG-----GSEDCD 227
+ Q GK+ +LP+ + P D PP P + + L E E S D
Sbjct: 496 VAPQSKEGKKGPRLPEK-ETLLSLPAKDTPPGVPEKSLGGSSLTETEAAPSLTLPSVDYI 554
Query: 228 VLEATQPLEQGFLQQLEEGPSSSGQHQPQQEEEESKPEPERSG 270
++ P + +LE SS+ + + + P+P G
Sbjct: 555 PQDSPTPSVRQIRNELEARLSSAAEKEAKPSIGSLPPKPRLEG 597
Score = 33.9 bits (76), Expect = 0.67
Identities = 63/268 (23%), Positives = 84/268 (31%), Gaps = 55/268 (20%)
Query: 2 MPPPFMPPPGIPPPFPPMGLP-PMSQR---PPAIPPMPPGILPPMLPPMGAPPP------ 51
+PPP P P PP PP P P +Q+ PPA P P L P PP
Sbjct: 396 LPPPAPPLPPPAPPLPPAAPPLPCAQKAAHPPAGFTKTPKSSSPALKPKPNPPSPENTAS 455
Query: 52 --------------------------------LTQIPG--MVPPMMPGMLMPAVP--VTA 75
L+ PG + P G P +P T
Sbjct: 456 SAPVDWRDPSQMEKLRNELAAYLCGSRREDRFLSHRPGPTVAPQSKEGKKGPRLPEKETL 515
Query: 76 ATAPGADTASSAVAGTGPPRALWSEHVAPDGRIYYYNADDKQSVWEKPSVLKSKAELLLS 135
+ P DT + +L AP + + + S ++++ E LS
Sbjct: 516 LSLPAKDTPPGVPEKSLGGSSLTETEAAPSLTLPSVDYIPQDSPTPSVRQIRNELEARLS 575
Query: 136 QCPWKEYKSDTG----KPYYYNNQSKESRWTRPKDLDDLEVLVKQEAAGKQQQQLPQT-L 190
KE K G KP + E+ D D L V + + LP T L
Sbjct: 576 SAAEKEAKPSIGSLPPKPRLEGGRICEN----GADDDKLSKPVAKNLPPQSTTLLPTTSL 631
Query: 191 QPQPPQPQPDPPPVPPGPTPVPTGLLEP 218
QP+ PP P P P L P
Sbjct: 632 QPKAMLGPAIPPKATPEPAIPPKATLWP 659
Score = 30.0 bits (66), Expect = 9.7
Identities = 12/22 (54%), Positives = 13/22 (59%)
Query: 202 PPVPPGPTPVPTGLLEPEPGGS 223
PP PPGP P P + PGGS
Sbjct: 140 PPPPPGPAPGPPQDISEPPGGS 161
>gi|239742884 PREDICTED: hypothetical protein LOC647024 [Homo
sapiens]
Length = 1188
Score = 60.1 bits (144), Expect = 9e-09
Identities = 78/288 (27%), Positives = 100/288 (34%), Gaps = 60/288 (20%)
Query: 3 PPPFMPPPGIPPPFP-PMGLPPMSQRPPAIPPMPPGILPPMLPPMGAPPP---------- 51
PPP P PG P P G P+ P PP PP +L P PP APPP
Sbjct: 141 PPPPGPAPGPPQDISEPPGGSPLPSPPSTAPPPPPLLLEPPPPPSMAPPPPPVLEALSPP 200
Query: 52 -------LTQIPGMVPPMMP-GMLMPAVPVTAATAPGADTASSAVAGTG--PPRAL--WS 99
+ P +PP P L P P A AP A AS GT PP + W
Sbjct: 201 HTLSSPSIPTPPDFIPPAPPLAFLAPPPPPVPAPAPPA-PASPHTVGTRLFPPGGVTKWK 259
Query: 100 EHVAPDGRIYYYNADDKQSVWEKPSVLKSKAELLLSQCPWKEYKSDTGKPYYYNNQSKES 159
VA +GR Q+ + S +S AE P +P+ +S +
Sbjct: 260 SDVALNGR---------QAEATRASPPRSPAE------PKGSALGPNPEPHLTFPRSFKV 304
Query: 160 RWTRPKDLDDLEVLVKQEAAGKQQQQLPQTLQPQPPQPQPDPPPVPPGPTPVPTGLLEPE 219
P + V QEA K++ + P P+PP P + P+
Sbjct: 305 PPPTPVRTSSIPVQEAQEAPRKEEGATKKA---------PSRLPLPPSFHIRPASQVYPD 355
Query: 220 PGGSEDC-DVLEATQPLEQGFLQQLEEGPSSSGQHQPQQEEEESKPEP 266
DC L+AT P GQ Q Q +E P P
Sbjct: 356 RAPEPDCPGELKATAPASPRL-----------GQSQSQADERAGTPPP 392
Score = 43.1 bits (100), Expect = 0.001
Identities = 27/72 (37%), Positives = 34/72 (47%), Gaps = 4/72 (5%)
Query: 11 GIPPPFPPMGLPPMSQRPPAIPPMPPGILPPMLPPMGAPPP--LTQIP-GMVPPMMPGML 67
G PPP PP+ PP PP PP+PP P A PP T+ P P + P
Sbjct: 388 GTPPPAPPLP-PPAPPLPPPAPPLPPAAPPLPCAQKAAHPPAGFTKTPKSSSPALKPKPN 446
Query: 68 MPAVPVTAATAP 79
P+ TA++AP
Sbjct: 447 PPSPENTASSAP 458
Score = 35.8 bits (81), Expect = 0.18
Identities = 28/95 (29%), Positives = 33/95 (34%), Gaps = 10/95 (10%)
Query: 9 PPGIPPPFPPMGLPPMSQRPPAIPPM--------PPGILPPMLPPMGAPPPLTQIPGMVP 60
PP P L P + PAIPP P L P PP P T +
Sbjct: 619 PPQSTTLLPTTSLQPKAMLGPAIPPKATPEPAIPPKATLWPATPPKATLGPATPLKATSG 678
Query: 61 PMMP--GMLMPAVPVTAATAPGADTASSAVAGTGP 93
P P PA+ TA T P + A +GP
Sbjct: 679 PTTPLKATSGPAIASTATTLPTTTSQLMAEKDSGP 713
Score = 35.0 bits (79), Expect = 0.30
Identities = 24/75 (32%), Positives = 29/75 (38%), Gaps = 8/75 (10%)
Query: 31 IPPMPPGILPPMLPPMGAPP---PLTQIPGMVPPMMPGMLMPAVPVTAATAPGADTASSA 87
IPP PPG P + PP PL P PP P +L P P + A P
Sbjct: 139 IPPPPPGPAPGPPQDISEPPGGSPLPSPPSTAPPPPPLLLEPPPPPSMAPPP-----PPV 193
Query: 88 VAGTGPPRALWSEHV 102
+ PP L S +
Sbjct: 194 LEALSPPHTLSSPSI 208
Score = 34.3 bits (77), Expect = 0.52
Identities = 63/283 (22%), Positives = 94/283 (33%), Gaps = 55/283 (19%)
Query: 4 PPFMPPPGIP-------PPFPPMGLPPMS--QRPPAIPPMPPGILPPMLPPMGAPPPLTQ 54
P P P P P P +G +R PP PP LPP PP+ PPP
Sbjct: 354 PDRAPEPDCPGELKATAPASPRLGQSQSQADERAGTPPPAPP--LPPPAPPL--PPPAPP 409
Query: 55 IPGMVPPMMPGMLMPAVPVTAATAPGADTASSAVAGTGPPRALWSEHVAPDGRIYYYNAD 114
+P PP +P A P T ++ + PP +P+ A
Sbjct: 410 LPPAAPP-LPCAQKAAHPPAGFTKTPKSSSPALKPKPNPP--------SPEN-----TAS 455
Query: 115 DKQSVWEKPSVLKSKAELLLSQCPWKEYKSDTGKPYYYNNQSKESRWT--RPKDLDDLEV 172
W PS ++ L + Y +E R+ RP
Sbjct: 456 SAPVDWRDPSQMEKLRNELAA---------------YLCGSRREDRFLSHRPG-----PT 495
Query: 173 LVKQEAAGKQQQQLPQTLQPQPPQPQPDPPPVPPGPTPVPTGLLEPEPG-----GSEDCD 227
+ Q GK+ +LP+ + P D PP P + + L E E S D
Sbjct: 496 VAPQSKEGKKGPRLPEK-ETLLSLPAKDTPPGVPEKSLGGSSLTETEAAPSLTLPSVDYI 554
Query: 228 VLEATQPLEQGFLQQLEEGPSSSGQHQPQQEEEESKPEPERSG 270
++ P + +LE SS+ + + + P+P G
Sbjct: 555 PQDSPTPSVRQIRNELEARLSSAAEKEAKPSIGSLPPKPRLEG 597
Score = 33.9 bits (76), Expect = 0.67
Identities = 63/268 (23%), Positives = 84/268 (31%), Gaps = 55/268 (20%)
Query: 2 MPPPFMPPPGIPPPFPPMGLP-PMSQR---PPAIPPMPPGILPPMLPPMGAPPP------ 51
+PPP P P PP PP P P +Q+ PPA P P L P PP
Sbjct: 396 LPPPAPPLPPPAPPLPPAAPPLPCAQKAAHPPAGFTKTPKSSSPALKPKPNPPSPENTAS 455
Query: 52 --------------------------------LTQIPG--MVPPMMPGMLMPAVP--VTA 75
L+ PG + P G P +P T
Sbjct: 456 SAPVDWRDPSQMEKLRNELAAYLCGSRREDRFLSHRPGPTVAPQSKEGKKGPRLPEKETL 515
Query: 76 ATAPGADTASSAVAGTGPPRALWSEHVAPDGRIYYYNADDKQSVWEKPSVLKSKAELLLS 135
+ P DT + +L AP + + + S ++++ E LS
Sbjct: 516 LSLPAKDTPPGVPEKSLGGSSLTETEAAPSLTLPSVDYIPQDSPTPSVRQIRNELEARLS 575
Query: 136 QCPWKEYKSDTG----KPYYYNNQSKESRWTRPKDLDDLEVLVKQEAAGKQQQQLPQT-L 190
KE K G KP + E+ D D L V + + LP T L
Sbjct: 576 SAAEKEAKPSIGSLPPKPRLEGGRICEN----GADDDKLSKPVAKNLPPQSTTLLPTTSL 631
Query: 191 QPQPPQPQPDPPPVPPGPTPVPTGLLEP 218
QP+ PP P P P L P
Sbjct: 632 QPKAMLGPAIPPKATPEPAIPPKATLWP 659
Score = 30.0 bits (66), Expect = 9.7
Identities = 12/22 (54%), Positives = 13/22 (59%)
Query: 202 PPVPPGPTPVPTGLLEPEPGGS 223
PP PPGP P P + PGGS
Sbjct: 140 PPPPPGPAPGPPQDISEPPGGS 161
>gi|6005948 WW domain-containing binding protein 4 [Homo sapiens]
Length = 376
Score = 60.1 bits (144), Expect = 9e-09
Identities = 53/222 (23%), Positives = 84/222 (37%), Gaps = 31/222 (13%)
Query: 66 MLMPAVPVTAATAPGADTASSAVAGT-------GPPRALWSEHVAPDGRIYYYNADDKQS 118
+L P++ +T P T++ P + W E + +G YYY+ S
Sbjct: 89 ILEPSITPVTSTIPPTSTSNQQKEKKEKKKRKKDPSKGRWVEGITSEGYHYYYDLISGAS 148
Query: 119 VWEKPSVLKSKAELLLSQCPWKEYKSDTGKPYYYNNQSKESRWTRPKDLDDLEVLVKQEA 178
WEKP + + + W E S+ G YYYN ++ ESRW +P DD
Sbjct: 149 QWEKPEGFQGDLKKTAVKTVWVEGLSEDGFTYYYNTETGESRWEKP---DDFIPHTSDLP 205
Query: 179 AGKQQQQLPQTLQPQPPQPQPDPPPVPPGPTPVPTGLLEPEPGGSEDCDVLEATQPLEQG 238
+ K + TL G E E GG + E+
Sbjct: 206 SSKVNENSLGTLDESKSSDSHSD----------SDGEQEAEEGG--------VSTETEKP 247
Query: 239 FLQQLEEGPSSSGQHQPQQEEEESKPEPERSGLSWSNREKAK 280
++ E+ +S G P+ ++E+S + G SN EK+K
Sbjct: 248 KIKFKEKNKNSDGGSDPETQKEKSIQKQNSLG---SNEEKSK 286
>gi|11386183 WAS protein family, member 2 [Homo sapiens]
Length = 498
Score = 59.3 bits (142), Expect = 1e-08
Identities = 41/111 (36%), Positives = 48/111 (43%), Gaps = 17/111 (15%)
Query: 3 PPPFMPPP-----GIPPPFPPMGL----PPMSQRPPAIPPMPPGILPPMLPPMGA----- 48
PPP PPP GIPPP PP+G P PP+ PP P PP PP A
Sbjct: 318 PPPAPPPPPPPMIGIPPPPPPVGFGSPGTPPPPSPPSFPPHPDFAAPPPPPPPPAADYPT 377
Query: 49 --PPPLTQIPGMVPPMMPGMLMPAVPVTAAT-APGADTASSAVAGTGPPRA 96
PPPL+Q G PP P P P T A G ++ T P++
Sbjct: 378 LPPPPLSQPTGGAPPPPPPPPPPGPPPPPFTGADGQPAIPPPLSDTTKPKS 428
Score = 51.2 bits (121), Expect = 4e-06
Identities = 36/100 (36%), Positives = 40/100 (40%), Gaps = 18/100 (18%)
Query: 10 PGIPPPFPPMGLPPMSQRPPAIPPMPPGILPPMLPPMGAPPPLTQI----PGMVPPMMPG 65
P PPP PP+G PP + A PP PP PP P +G PPP + PG PP P
Sbjct: 297 PSHPPPAPPLGSPPGPKPGFAPPPAPP---PPPPPMIGIPPPPPPVGFGSPGTPPPPSPP 353
Query: 66 MLMP----AVPVTAATAPGAD-------TASSAVAGTGPP 94
P A P P AD S G PP
Sbjct: 354 SFPPHPDFAAPPPPPPPPAADYPTLPPPPLSQPTGGAPPP 393
Score = 49.7 bits (117), Expect = 1e-05
Identities = 37/101 (36%), Positives = 40/101 (39%), Gaps = 11/101 (10%)
Query: 4 PPFMPPPG-----IPPPFPPMGLPPMSQRPPAIPPM---PPGILPPMLPPMGAPPPLTQI 55
PP PPG PPP PP PPM PP PP+ PG PP PP P P
Sbjct: 304 PPLGSPPGPKPGFAPPPAPPPPPPPMIGIPPPPPPVGFGSPGTPPPPSPPSFPPHPDFAA 363
Query: 56 PGMVPPMMPGMLMPAVPVTAATAP--GADTASSAVAGTGPP 94
P PP P P +P + P GA GPP
Sbjct: 364 P-PPPPPPPAADYPTLPPPPLSQPTGGAPPPPPPPPPPGPP 403
Score = 41.6 bits (96), Expect = 0.003
Identities = 31/96 (32%), Positives = 40/96 (41%), Gaps = 16/96 (16%)
Query: 4 PPFMPPPGIPPP----FPPMGLPPMSQRP---PAIPPMPPGILPPMLPPMGAPPPLTQIP 56
P F PP PPP +P + PP+SQ P PP PP PP PPP T
Sbjct: 359 PDFAAPPPPPPPPAADYPTLPPPPLSQPTGGAPPPPPPPPPPGPP-------PPPFTGAD 411
Query: 57 GM--VPPMMPGMLMPAVPVTAATAPGADTASSAVAG 90
G +PP + P + A + +D S+ G
Sbjct: 412 GQPAIPPPLSDTTKPKSSLPAVSDARSDLLSAIRQG 447
Score = 34.7 bits (78), Expect = 0.39
Identities = 14/26 (53%), Positives = 14/26 (53%)
Query: 187 PQTLQPQPPQPQPDPPPVPPGPTPVP 212
P QP P P PPP PPGP P P
Sbjct: 381 PPLSQPTGGAPPPPPPPPPPGPPPPP 406
Score = 33.1 bits (74), Expect = 1.1
Identities = 14/29 (48%), Positives = 15/29 (51%)
Query: 192 PQPPQPQPDPPPVPPGPTPVPTGLLEPEP 220
P PP P D P +PP P PTG P P
Sbjct: 366 PPPPPPAADYPTLPPPPLSQPTGGAPPPP 394
Score = 32.0 bits (71), Expect = 2.6
Identities = 26/85 (30%), Positives = 31/85 (36%), Gaps = 17/85 (20%)
Query: 3 PPPFMPPPGIPPPFPPMGLPPMSQR---------PPAIPPMPPGILPPMLPPMG-----A 48
P P +PPP P +QR + P P PP+ P G A
Sbjct: 258 PSPSFSEDNLPPPPAEFSYPVDNQRGSGLAGPKRSSVVSPSHPPPAPPLGSPPGPKPGFA 317
Query: 49 PPPLTQIPGMVPPMMPGMLMPAVPV 73
PPP P PP M G+ P PV
Sbjct: 318 PPPAPPPP---PPPMIGIPPPPPPV 339
Score = 32.0 bits (71), Expect = 2.6
Identities = 14/29 (48%), Positives = 16/29 (55%), Gaps = 2/29 (6%)
Query: 194 PPQPQPD--PPPVPPGPTPVPTGLLEPEP 220
PP P+P PPP PP P P G+ P P
Sbjct: 309 PPGPKPGFAPPPAPPPPPPPMIGIPPPPP 337
Score = 30.0 bits (66), Expect = 9.7
Identities = 13/24 (54%), Positives = 14/24 (58%), Gaps = 3/24 (12%)
Query: 194 PPQPQPDPPP---VPPGPTPVPTG 214
PP P P PPP +PP P PV G
Sbjct: 319 PPAPPPPPPPMIGIPPPPPPVGFG 342
>gi|150170670 piccolo isoform 2 [Homo sapiens]
Length = 4935
Score = 59.3 bits (142), Expect = 1e-08
Identities = 86/361 (23%), Positives = 126/361 (34%), Gaps = 54/361 (14%)
Query: 3 PPPFMPPPGIPPPFPPMGLPPMSQRPPAIPPMPPGILPPMLPPMGAPPPLTQIPGMV--P 60
PPP P P PPP P P SQ+P + P PP P P P Q PG P
Sbjct: 479 PPPQQPGPAKPPPQQPGSAKPPSQQPGSTKP------PPQQPGPAKPSP--QQPGSTKPP 530
Query: 61 PMMPGMLMPAVPVTAATAPGADTASSAVAGTGPPRALWSEHVAPDGRIYYYNADDKQSVW 120
PG P+ + P A ++ V+ TG + L V+P + Q +
Sbjct: 531 SQQPGSAKPSAQQPSPAKPSAQQSTKPVSQTGSGKPLQPPTVSPSAK-----QPPSQGLP 585
Query: 121 EKPSVLKSKAELLLSQCPWKEYKSDTGKPYYYNNQ---SKESRWTRPKDLDDLEVLVKQE 177
+ L + ELLL + + T + + T K+ L +K+
Sbjct: 586 KTICPLCNTTELLLHVPEKANFNTCTECQTTVCSLCGFNPNPHLTEVKEWLCLNCQMKRA 645
Query: 178 AAGKQQQQLPQTLQPQPPQPQPDPPPVP---------PGPTPVPTGLLEPEPGGSEDCDV 228
G L P P PQP P P P T P+ + D+
Sbjct: 646 LGG--------DLAPVPSSPQPKLKTAPVTTTSAVSKSSPQPQQT---SPKKDAAPKQDL 694
Query: 229 LEATQPLEQGFL--QQLEEGPSSSGQHQPQQEEEESKPEPERSGLSWSNREKAKQAFKEL 286
+A +P + L Q G S+ QP + + SKP P + S ++KA A +
Sbjct: 695 SKAPEPKKPPPLVKQPTLHGSPSAKAKQPPEADSLSKPAPPKEPSVPSEQDKAPVADDKP 754
Query: 287 LRDKAVPSNASWEQAMKMVVTDPRYSALPKLSEKKQAFNAYKAQREKEEKEEARLRAKEA 346
+ K V +V+ + P + K Q + EEK L+ A
Sbjct: 755 KQPKMVKPTTD-------LVSSSSATTKPDIPSS-------KVQSQAEEKTTPPLKTDSA 800
Query: 347 K 347
K
Sbjct: 801 K 801
Score = 58.5 bits (140), Expect = 3e-08
Identities = 72/270 (26%), Positives = 98/270 (36%), Gaps = 28/270 (10%)
Query: 5 PFMPPPGIPP-PFPPMGLPPMSQRPPAIPPMPPGILPPMLPPMGAPPPLTQIPGMV-PPM 62
P +P P PP P G PP Q P PG P P G PL Q PG V PP+
Sbjct: 296 PSLPSPSKPPIQQPTPGKPPAQQ--PGHEKSQPGPAKPPAQPSGLTKPLAQQPGTVKPPV 353
Query: 63 MP--GMLMPAVPVTAATAPGADTASSAVAGTGP-PRALWSEHVAPDGRIYYYNADDKQSV 119
P PA P+ A P T S + P P+AL P G +Q
Sbjct: 354 QPPGTTKPPAQPLGPAKPPAQQTGSEKPSSEQPGPKAL----AQPPG---VGKTPAQQPG 406
Query: 120 WEKPSVLKSKAELLLSQCPWKEYKSDTGKPYYYNNQSKESRWTRPKDLDDLEVLVKQEAA 179
KP + L+Q P + + P Q + + +Q
Sbjct: 407 PAKPPTQQVGTPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGP 466
Query: 180 GKQQQQLPQTLQPQPPQPQP-DPPPVPPGPTPVPTGLLEPEPGGSEDCDVLEATQPLEQG 238
K QLP +P P QP P PPP PG P+ +PG ++ P + G
Sbjct: 467 TKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPS----QQPGSTK-------PPPQQPG 515
Query: 239 FLQQLEEGPSSSGQHQPQQEEEESKPEPER 268
+ + P S+ P Q+ +KP ++
Sbjct: 516 PAKPSPQQPGST--KPPSQQPGSAKPSAQQ 543
Score = 46.2 bits (108), Expect = 1e-04
Identities = 53/230 (23%), Positives = 72/230 (31%), Gaps = 44/230 (19%)
Query: 4 PPFMPPPGIPPPFPPMG--LPPMSQ-----------------RPPAI---PPMPPGILPP 41
PP PP PP P+G PP Q +PP + P PG P
Sbjct: 351 PPVQPPGTTKPPAQPLGPAKPPAQQTGSEKPSSEQPGPKALAQPPGVGKTPAQQPGPAKP 410
Query: 42 MLPPMGAPPPLTQIPGMVPPMMPGMLMPAVPVTAATAPGADTASSAVAGTGPPRALWSEH 101
+G P PL Q PG+ P P T PG + AG G A +
Sbjct: 411 PTQQVGTPKPLAQQPGLQSPAK----APGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGP 466
Query: 102 VAPDGRIYYYNADDKQSVWEKPSVLKSKAELLLSQCPWKEYKSDTGKPYYYNNQSKESRW 161
P ++ + ++P K + S P + T P +K S
Sbjct: 467 TKPPSQL----PGPAKPPPQQPGPAKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPS-- 520
Query: 162 TRPKDLDDLEVLVKQEAAGKQQQQLPQTLQPQPPQPQPDPPPVPPGPTPV 211
+Q + K Q P + +P QP P P PV
Sbjct: 521 ------------PQQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQSTKPV 558
Score = 39.7 bits (91), Expect = 0.012
Identities = 33/121 (27%), Positives = 43/121 (35%), Gaps = 12/121 (9%)
Query: 8 PPPGIPPPFPPMGLPPMSQRPPAIPPMPPGILPPMLPPMGAPPPLTQIPGMVPPMMPGML 67
PPP PPP PP PP PP PP LPP P P ++ P L
Sbjct: 2405 PPPPPPPPPPP---------PPPPPPPPPPPLPPPTSPKPTILPKKKLTVASPVTTATPL 2455
Query: 68 MPAVPV--TAATAPGADTASSAVAGTGPPRALWSEHVAPDGRIYYYNAD-DKQSVWEKPS 124
AV T A + + T PP P G ++ + + K + KP
Sbjct: 2456 FDAVTTLETTAVLRSNGLPVTRICTTAPPPVPPKPSSIPSGLVFTHRPEPSKPPIAPKPV 2515
Query: 125 V 125
+
Sbjct: 2516 I 2516
Score = 38.9 bits (89), Expect = 0.021
Identities = 27/70 (38%), Positives = 32/70 (45%), Gaps = 5/70 (7%)
Query: 10 PGIPPPFPPMGLPPMSQRPPAIPPMPPGILPPMLPP--MGAPPPLTQIPGMVPPMMPGML 67
P P PF +S +PP PP PP PP PP PPP + P ++P L
Sbjct: 2387 PAKPRPFFRSSSLDISAQPPPPPPPPPPPPPPPPPPPPPPLPPPTSPKPTILPKK---KL 2443
Query: 68 MPAVPVTAAT 77
A PVT AT
Sbjct: 2444 TVASPVTTAT 2453
Score = 38.1 bits (87), Expect = 0.036
Identities = 100/419 (23%), Positives = 141/419 (33%), Gaps = 99/419 (23%)
Query: 8 PPPGIPPPFPPMGLPPMSQRPPAIPPMPPGI--LPPMLPPMGAPPPLTQIPGMVP---PM 62
P P PPP P + P A PP L PP P Q V P
Sbjct: 698 PEPKKPPPLVKQ--PTLHGSPSAKAKQPPEADSLSKPAPPKEPSVPSEQDKAPVADDKPK 755
Query: 63 MPGMLMPAVPVTAATA-------PGADTASSAVAGTGPP----RALWSEHVAPDGRIYYY 111
P M+ P + ++++ P + S A T PP A S+ P G
Sbjct: 756 QPKMVKPTTDLVSSSSATTKPDIPSSKVQSQAEEKTTPPLKTDSAKPSQSFPPTG----- 810
Query: 112 NADDKQSVWEKPSVLKSKAELLLSQCPWKEYKSDTGKPYYYNNQSKESRWTRPKDLDDLE 171
EK S SKA + K + S ES+ K +D ++
Sbjct: 811 ---------EKVSPFDSKAI---------PRPASDSKIISHPGPSSESKGQ--KQVDPVQ 850
Query: 172 VLVKQEAAGKQQQQLPQTLQPQPP-QPQPDPPPVPPGPTP-----VPTGLLEPEP----- 220
K+E K Q ++ P+P +P P P PPGP P VPT P+P
Sbjct: 851 ---KKEEPKKAQTKM----SPKPDAKPMPKGSPTPPGPRPTAGQTVPTPQQSPKPQEQSR 903
Query: 221 ------GGSEDCDVLEATQPLEQ------GF----LQQLEEGPSSSGQHQPQQEE----- 259
G D + T P E GF Q S++GQ P +
Sbjct: 904 RFSLNLGSITDAPKSQPTTPQETVTGKLFGFGASIFSQASNLISTAGQPGPHSQSGPGAP 963
Query: 260 EESKPEPERSGLSWSNREKAKQAFKELLRDKAVPSNASWEQAMKMVVTDPRYSALPKLSE 319
+ P P + S + QA K++P V + + A KL
Sbjct: 964 MKQAPAPSQPPTSQGPPKSTGQA--PPAPAKSIP-----------VKKETKAPAAEKLEP 1010
Query: 320 K-KQAFNAYKAQREKEE---KEEARLRAKEAKQTLQHFLEQHERMTSTTRYRRAEQTFG 374
K +QA + + EK+ K+ L A+ K L LE+ + ST + E G
Sbjct: 1011 KAEQAPTVKRTETEKKPPPIKDSKSLTAEPQKAVLPTKLEKSPKPESTCPLCKTELNIG 1069
Score = 38.1 bits (87), Expect = 0.036
Identities = 17/34 (50%), Positives = 18/34 (52%), Gaps = 3/34 (8%)
Query: 187 PQTLQPQPPQPQPDPPPVPPGPTPVPTGLLEPEP 220
P P PP P P PPP PP P P PT P+P
Sbjct: 2405 PPPPPPPPPPPPPPPPPPPPPPLPPPT---SPKP 2435
Score = 38.1 bits (87), Expect = 0.036
Identities = 17/31 (54%), Positives = 18/31 (58%)
Query: 3 PPPFMPPPGIPPPFPPMGLPPMSQRPPAIPP 33
PPP PPP PPP PP LPP + P I P
Sbjct: 2409 PPPPPPPPPPPPPPPPPPLPPPTSPKPTILP 2439
Score = 38.1 bits (87), Expect = 0.036
Identities = 32/113 (28%), Positives = 42/113 (37%), Gaps = 41/113 (36%)
Query: 3 PPPFMPPPGIPPPFPPMGLPPMSQRPPAIPPMPPGILPPM-------------------- 42
PPP PPP PPP PP PP S +P +P + P+
Sbjct: 2410 PPPPPPPPPPPPPPPPPLPPPTSPKPTILPKKKLTVASPVTTATPLFDAVTTLETTAVLR 2469
Query: 43 ---LP--------PMGAPPPLTQIP-GMV---------PPMMPGMLMPAVPVT 74
LP P PP + IP G+V PP+ P ++P +P T
Sbjct: 2470 SNGLPVTRICTTAPPPVPPKPSSIPSGLVFTHRPEPSKPPIAPKPVIPQLPTT 2522
Score = 37.7 bits (86), Expect = 0.047
Identities = 15/31 (48%), Positives = 17/31 (54%)
Query: 182 QQQQLPQTLQPQPPQPQPDPPPVPPGPTPVP 212
+ L + QP PP P P PPP PP P P P
Sbjct: 2395 RSSSLDISAQPPPPPPPPPPPPPPPPPPPPP 2425
Score = 37.0 bits (84), Expect = 0.080
Identities = 36/124 (29%), Positives = 54/124 (43%), Gaps = 8/124 (6%)
Query: 719 EEEELPPPSLRP-PKRRRRNPSESGSEPSSSLDSVESGGAALGGRGSPSSHLLGADHGLR 777
EE EL SL P+ R R S SS + S SS H
Sbjct: 1695 EEPELEMESLTDSPEDRSRGEGSSSLHASSFTPGTSPTSVSSLDEDSDSS----PSHKKG 1750
Query: 778 KAKKPKKKTKKRRHKSNSPESETDPEEKAGKESDEKEQEQDKDRELQQAELPNRSPGFGI 837
++K+ ++K + R H P E EE+ +E +E +EQ+K RE++Q + +S
Sbjct: 1751 ESKQ-QRKARHRPHGPLLPTIEDSSEEEELREEEELLKEQEKQREIEQQQ--RKSSSKKS 1807
Query: 838 KKEK 841
KK+K
Sbjct: 1808 KKDK 1811
Score = 37.0 bits (84), Expect = 0.080
Identities = 15/29 (51%), Positives = 16/29 (55%)
Query: 190 LQPQPPQPQPDPPPVPPGPTPVPTGLLEP 218
+ QPP P P PPP PP P P P L P
Sbjct: 2401 ISAQPPPPPPPPPPPPPPPPPPPPPPLPP 2429
Score = 37.0 bits (84), Expect = 0.080
Identities = 21/47 (44%), Positives = 24/47 (51%), Gaps = 4/47 (8%)
Query: 3 PPPFMPPPGIPPPFPPMGLPPMSQRPPAIPPMPPGILPPMLPPMGAP 49
PPP PPP PPP PP PP+ PP P P ILP + +P
Sbjct: 2406 PPPPPPPPPPPPPPPPPPPPPL---PPPTSPKPT-ILPKKKLTVASP 2448
Score = 36.6 bits (83), Expect = 0.10
Identities = 14/27 (51%), Positives = 16/27 (59%)
Query: 187 PQTLQPQPPQPQPDPPPVPPGPTPVPT 213
P P PP P P PPP+PP +P PT
Sbjct: 2410 PPPPPPPPPPPPPPPPPLPPPTSPKPT 2436
Score = 34.7 bits (78), Expect = 0.39
Identities = 81/385 (21%), Positives = 128/385 (33%), Gaps = 70/385 (18%)
Query: 3 PPPFMPPPGIPPPFPPMGLPPMSQRP-----------PAIPPMPPG------------IL 39
PPP P P P P P P SQ+P PA P +
Sbjct: 509 PPPQQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQSTKPVSQTGSGKPLQ 568
Query: 40 PPMLPPMGAPPPLTQIPGMVPPMM-PGMLMPAVPVTA--ATAPGADTASSAVAGTGPPRA 96
PP + P PP +P + P+ L+ VP A T T ++ G P
Sbjct: 569 PPTVSPSAKQPPSQGLPKTICPLCNTTELLLHVPEKANFNTCTECQTTVCSLCGFNP--- 625
Query: 97 LWSEHVAPDGRIYYYNADDKQSVWEKPSVLKSKAELLLSQCPWKEYKSDTGKPYYYNNQS 156
+ H+ N K+++ + + S + L P + + S
Sbjct: 626 --NPHLTEVKEWLCLNCQMKRALGGDLAPVPSSPQPKLKTAPVTTTSA-------VSKSS 676
Query: 157 KESRWTRPKDLDDLEVLVKQEAAGKQQ-QQLPQTLQPQPPQPQP---DPPPVPPGPTPVP 212
+ + T P K++AA KQ + P+ +P P QP P P
Sbjct: 677 PQPQQTSP----------KKDAAPKQDLSKAPEPKKPPPLVKQPTLHGSPSAKAKQPPEA 726
Query: 213 TGLLEPEPGGSEDCDVLEATQPLEQGFLQQLEEGPSSSGQHQP-----QQEEEESKPEPE 267
L +P P E + P EQ ++ P +P +KP+
Sbjct: 727 DSLSKPAP-------PKEPSVPSEQDKAPVADDKPKQPKMVKPTTDLVSSSSATTKPDIP 779
Query: 268 RSGLSWSNREKAKQAFKELLRDKAVPSNASWEQAMKMVVTDPRYSALPK-LSEKKQAFNA 326
S + EK K D A PS + K+ D + A+P+ S+ K +
Sbjct: 780 SSKVQSQAEEKTTPPLK---TDSAKPSQSFPPTGEKVSPFDSK--AIPRPASDSKIISHP 834
Query: 327 YKAQREKEEKEEARLRAKEAKQTLQ 351
+ K +K+ ++ KE + Q
Sbjct: 835 GPSSESKGQKQVDPVQKKEEPKKAQ 859
Score = 33.5 bits (75), Expect = 0.88
Identities = 14/27 (51%), Positives = 14/27 (51%)
Query: 184 QQLPQTLQPQPPQPQPDPPPVPPGPTP 210
Q P P PP P P PPP PP P P
Sbjct: 2404 QPPPPPPPPPPPPPPPPPPPPPPLPPP 2430
Score = 32.3 bits (72), Expect = 2.0
Identities = 25/92 (27%), Positives = 27/92 (29%), Gaps = 15/92 (16%)
Query: 3 PPPFMPPPGIPPPFP---PMGLPPMSQRPPAIPPMPPGI------------LPPMLPPMG 47
P P PG+ P P P P IP G P LP
Sbjct: 418 PKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQLPGPA 477
Query: 48 APPPLTQIPGMVPPMMPGMLMPAVPVTAATAP 79
PPP P PP PG P +T P
Sbjct: 478 KPPPQQPGPAKPPPQQPGSAKPPSQQPGSTKP 509
Score = 32.0 bits (71), Expect = 2.6
Identities = 13/26 (50%), Positives = 14/26 (53%)
Query: 187 PQTLQPQPPQPQPDPPPVPPGPTPVP 212
P P PP P P PPP P PT +P
Sbjct: 2414 PPPPPPPPPPPPPLPPPTSPKPTILP 2439
Score = 32.0 bits (71), Expect = 2.6
Identities = 13/23 (56%), Positives = 17/23 (73%), Gaps = 3/23 (13%)
Query: 201 PPPVPPGPTPVPTGLL---EPEP 220
PPPVPP P+ +P+GL+ PEP
Sbjct: 2483 PPPVPPKPSSIPSGLVFTHRPEP 2505
Score = 30.4 bits (67), Expect = 7.4
Identities = 13/25 (52%), Positives = 13/25 (52%)
Query: 196 QPQPDPPPVPPGPTPVPTGLLEPEP 220
QP P PPP PP P P P P P
Sbjct: 2404 QPPPPPPPPPPPPPPPPPPPPPPLP 2428
>gi|150378539 piccolo isoform 1 [Homo sapiens]
Length = 5142
Score = 59.3 bits (142), Expect = 1e-08
Identities = 86/361 (23%), Positives = 126/361 (34%), Gaps = 54/361 (14%)
Query: 3 PPPFMPPPGIPPPFPPMGLPPMSQRPPAIPPMPPGILPPMLPPMGAPPPLTQIPGMV--P 60
PPP P P PPP P P SQ+P + P PP P P P Q PG P
Sbjct: 479 PPPQQPGPAKPPPQQPGSAKPPSQQPGSTKP------PPQQPGPAKPSP--QQPGSTKPP 530
Query: 61 PMMPGMLMPAVPVTAATAPGADTASSAVAGTGPPRALWSEHVAPDGRIYYYNADDKQSVW 120
PG P+ + P A ++ V+ TG + L V+P + Q +
Sbjct: 531 SQQPGSAKPSAQQPSPAKPSAQQSTKPVSQTGSGKPLQPPTVSPSAK-----QPPSQGLP 585
Query: 121 EKPSVLKSKAELLLSQCPWKEYKSDTGKPYYYNNQ---SKESRWTRPKDLDDLEVLVKQE 177
+ L + ELLL + + T + + T K+ L +K+
Sbjct: 586 KTICPLCNTTELLLHVPEKANFNTCTECQTTVCSLCGFNPNPHLTEVKEWLCLNCQMKRA 645
Query: 178 AAGKQQQQLPQTLQPQPPQPQPDPPPVP---------PGPTPVPTGLLEPEPGGSEDCDV 228
G L P P PQP P P P T P+ + D+
Sbjct: 646 LGG--------DLAPVPSSPQPKLKTAPVTTTSAVSKSSPQPQQT---SPKKDAAPKQDL 694
Query: 229 LEATQPLEQGFL--QQLEEGPSSSGQHQPQQEEEESKPEPERSGLSWSNREKAKQAFKEL 286
+A +P + L Q G S+ QP + + SKP P + S ++KA A +
Sbjct: 695 SKAPEPKKPPPLVKQPTLHGSPSAKAKQPPEADSLSKPAPPKEPSVPSEQDKAPVADDKP 754
Query: 287 LRDKAVPSNASWEQAMKMVVTDPRYSALPKLSEKKQAFNAYKAQREKEEKEEARLRAKEA 346
+ K V +V+ + P + K Q + EEK L+ A
Sbjct: 755 KQPKMVKPTTD-------LVSSSSATTKPDIPSS-------KVQSQAEEKTTPPLKTDSA 800
Query: 347 K 347
K
Sbjct: 801 K 801
Score = 58.5 bits (140), Expect = 3e-08
Identities = 72/270 (26%), Positives = 98/270 (36%), Gaps = 28/270 (10%)
Query: 5 PFMPPPGIPP-PFPPMGLPPMSQRPPAIPPMPPGILPPMLPPMGAPPPLTQIPGMV-PPM 62
P +P P PP P G PP Q P PG P P G PL Q PG V PP+
Sbjct: 296 PSLPSPSKPPIQQPTPGKPPAQQ--PGHEKSQPGPAKPPAQPSGLTKPLAQQPGTVKPPV 353
Query: 63 MP--GMLMPAVPVTAATAPGADTASSAVAGTGP-PRALWSEHVAPDGRIYYYNADDKQSV 119
P PA P+ A P T S + P P+AL P G +Q
Sbjct: 354 QPPGTTKPPAQPLGPAKPPAQQTGSEKPSSEQPGPKAL----AQPPG---VGKTPAQQPG 406
Query: 120 WEKPSVLKSKAELLLSQCPWKEYKSDTGKPYYYNNQSKESRWTRPKDLDDLEVLVKQEAA 179
KP + L+Q P + + P Q + + +Q
Sbjct: 407 PAKPPTQQVGTPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGP 466
Query: 180 GKQQQQLPQTLQPQPPQPQP-DPPPVPPGPTPVPTGLLEPEPGGSEDCDVLEATQPLEQG 238
K QLP +P P QP P PPP PG P+ +PG ++ P + G
Sbjct: 467 TKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPS----QQPGSTK-------PPPQQPG 515
Query: 239 FLQQLEEGPSSSGQHQPQQEEEESKPEPER 268
+ + P S+ P Q+ +KP ++
Sbjct: 516 PAKPSPQQPGST--KPPSQQPGSAKPSAQQ 543
Score = 46.2 bits (108), Expect = 1e-04
Identities = 53/230 (23%), Positives = 72/230 (31%), Gaps = 44/230 (19%)
Query: 4 PPFMPPPGIPPPFPPMG--LPPMSQ-----------------RPPAI---PPMPPGILPP 41
PP PP PP P+G PP Q +PP + P PG P
Sbjct: 351 PPVQPPGTTKPPAQPLGPAKPPAQQTGSEKPSSEQPGPKALAQPPGVGKTPAQQPGPAKP 410
Query: 42 MLPPMGAPPPLTQIPGMVPPMMPGMLMPAVPVTAATAPGADTASSAVAGTGPPRALWSEH 101
+G P PL Q PG+ P P T PG + AG G A +
Sbjct: 411 PTQQVGTPKPLAQQPGLQSPAK----APGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGP 466
Query: 102 VAPDGRIYYYNADDKQSVWEKPSVLKSKAELLLSQCPWKEYKSDTGKPYYYNNQSKESRW 161
P ++ + ++P K + S P + T P +K S
Sbjct: 467 TKPPSQL----PGPAKPPPQQPGPAKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPS-- 520
Query: 162 TRPKDLDDLEVLVKQEAAGKQQQQLPQTLQPQPPQPQPDPPPVPPGPTPV 211
+Q + K Q P + +P QP P P PV
Sbjct: 521 ------------PQQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQSTKPV 558
Score = 39.7 bits (91), Expect = 0.012
Identities = 33/121 (27%), Positives = 43/121 (35%), Gaps = 12/121 (9%)
Query: 8 PPPGIPPPFPPMGLPPMSQRPPAIPPMPPGILPPMLPPMGAPPPLTQIPGMVPPMMPGML 67
PPP PPP PP PP PP PP LPP P P ++ P L
Sbjct: 2405 PPPPPPPPPPP---------PPPPPPPPPPPLPPPTSPKPTILPKKKLTVASPVTTATPL 2455
Query: 68 MPAVPV--TAATAPGADTASSAVAGTGPPRALWSEHVAPDGRIYYYNAD-DKQSVWEKPS 124
AV T A + + T PP P G ++ + + K + KP
Sbjct: 2456 FDAVTTLETTAVLRSNGLPVTRICTTAPPPVPPKPSSIPSGLVFTHRPEPSKPPIAPKPV 2515
Query: 125 V 125
+
Sbjct: 2516 I 2516
Score = 38.9 bits (89), Expect = 0.021
Identities = 27/70 (38%), Positives = 32/70 (45%), Gaps = 5/70 (7%)
Query: 10 PGIPPPFPPMGLPPMSQRPPAIPPMPPGILPPMLPP--MGAPPPLTQIPGMVPPMMPGML 67
P P PF +S +PP PP PP PP PP PPP + P ++P L
Sbjct: 2387 PAKPRPFFRSSSLDISAQPPPPPPPPPPPPPPPPPPPPPPLPPPTSPKPTILPKK---KL 2443
Query: 68 MPAVPVTAAT 77
A PVT AT
Sbjct: 2444 TVASPVTTAT 2453
Score = 38.1 bits (87), Expect = 0.036
Identities = 100/419 (23%), Positives = 141/419 (33%), Gaps = 99/419 (23%)
Query: 8 PPPGIPPPFPPMGLPPMSQRPPAIPPMPPGI--LPPMLPPMGAPPPLTQIPGMVP---PM 62
P P PPP P + P A PP L PP P Q V P
Sbjct: 698 PEPKKPPPLVKQ--PTLHGSPSAKAKQPPEADSLSKPAPPKEPSVPSEQDKAPVADDKPK 755
Query: 63 MPGMLMPAVPVTAATA-------PGADTASSAVAGTGPP----RALWSEHVAPDGRIYYY 111
P M+ P + ++++ P + S A T PP A S+ P G
Sbjct: 756 QPKMVKPTTDLVSSSSATTKPDIPSSKVQSQAEEKTTPPLKTDSAKPSQSFPPTG----- 810
Query: 112 NADDKQSVWEKPSVLKSKAELLLSQCPWKEYKSDTGKPYYYNNQSKESRWTRPKDLDDLE 171
EK S SKA + K + S ES+ K +D ++
Sbjct: 811 ---------EKVSPFDSKAI---------PRPASDSKIISHPGPSSESKGQ--KQVDPVQ 850
Query: 172 VLVKQEAAGKQQQQLPQTLQPQPP-QPQPDPPPVPPGPTP-----VPTGLLEPEP----- 220
K+E K Q ++ P+P +P P P PPGP P VPT P+P
Sbjct: 851 ---KKEEPKKAQTKM----SPKPDAKPMPKGSPTPPGPRPTAGQTVPTPQQSPKPQEQSR 903
Query: 221 ------GGSEDCDVLEATQPLEQ------GF----LQQLEEGPSSSGQHQPQQEE----- 259
G D + T P E GF Q S++GQ P +
Sbjct: 904 RFSLNLGSITDAPKSQPTTPQETVTGKLFGFGASIFSQASNLISTAGQPGPHSQSGPGAP 963
Query: 260 EESKPEPERSGLSWSNREKAKQAFKELLRDKAVPSNASWEQAMKMVVTDPRYSALPKLSE 319
+ P P + S + QA K++P V + + A KL
Sbjct: 964 MKQAPAPSQPPTSQGPPKSTGQA--PPAPAKSIP-----------VKKETKAPAAEKLEP 1010
Query: 320 K-KQAFNAYKAQREKEE---KEEARLRAKEAKQTLQHFLEQHERMTSTTRYRRAEQTFG 374
K +QA + + EK+ K+ L A+ K L LE+ + ST + E G
Sbjct: 1011 KAEQAPTVKRTETEKKPPPIKDSKSLTAEPQKAVLPTKLEKSPKPESTCPLCKTELNIG 1069
Score = 38.1 bits (87), Expect = 0.036
Identities = 17/34 (50%), Positives = 18/34 (52%), Gaps = 3/34 (8%)
Query: 187 PQTLQPQPPQPQPDPPPVPPGPTPVPTGLLEPEP 220
P P PP P P PPP PP P P PT P+P
Sbjct: 2405 PPPPPPPPPPPPPPPPPPPPPPLPPPT---SPKP 2435
Score = 38.1 bits (87), Expect = 0.036
Identities = 17/31 (54%), Positives = 18/31 (58%)
Query: 3 PPPFMPPPGIPPPFPPMGLPPMSQRPPAIPP 33
PPP PPP PPP PP LPP + P I P
Sbjct: 2409 PPPPPPPPPPPPPPPPPPLPPPTSPKPTILP 2439
Score = 38.1 bits (87), Expect = 0.036
Identities = 32/113 (28%), Positives = 42/113 (37%), Gaps = 41/113 (36%)
Query: 3 PPPFMPPPGIPPPFPPMGLPPMSQRPPAIPPMPPGILPPM-------------------- 42
PPP PPP PPP PP PP S +P +P + P+
Sbjct: 2410 PPPPPPPPPPPPPPPPPLPPPTSPKPTILPKKKLTVASPVTTATPLFDAVTTLETTAVLR 2469
Query: 43 ---LP--------PMGAPPPLTQIP-GMV---------PPMMPGMLMPAVPVT 74
LP P PP + IP G+V PP+ P ++P +P T
Sbjct: 2470 SNGLPVTRICTTAPPPVPPKPSSIPSGLVFTHRPEPSKPPIAPKPVIPQLPTT 2522
Score = 37.7 bits (86), Expect = 0.047
Identities = 15/31 (48%), Positives = 17/31 (54%)
Query: 182 QQQQLPQTLQPQPPQPQPDPPPVPPGPTPVP 212
+ L + QP PP P P PPP PP P P P
Sbjct: 2395 RSSSLDISAQPPPPPPPPPPPPPPPPPPPPP 2425
Score = 37.0 bits (84), Expect = 0.080
Identities = 36/124 (29%), Positives = 54/124 (43%), Gaps = 8/124 (6%)
Query: 719 EEEELPPPSLRP-PKRRRRNPSESGSEPSSSLDSVESGGAALGGRGSPSSHLLGADHGLR 777
EE EL SL P+ R R S SS + S SS H
Sbjct: 1695 EEPELEMESLTDSPEDRSRGEGSSSLHASSFTPGTSPTSVSSLDEDSDSS----PSHKKG 1750
Query: 778 KAKKPKKKTKKRRHKSNSPESETDPEEKAGKESDEKEQEQDKDRELQQAELPNRSPGFGI 837
++K+ ++K + R H P E EE+ +E +E +EQ+K RE++Q + +S
Sbjct: 1751 ESKQ-QRKARHRPHGPLLPTIEDSSEEEELREEEELLKEQEKQREIEQQQ--RKSSSKKS 1807
Query: 838 KKEK 841
KK+K
Sbjct: 1808 KKDK 1811
Score = 37.0 bits (84), Expect = 0.080
Identities = 15/29 (51%), Positives = 16/29 (55%)
Query: 190 LQPQPPQPQPDPPPVPPGPTPVPTGLLEP 218
+ QPP P P PPP PP P P P L P
Sbjct: 2401 ISAQPPPPPPPPPPPPPPPPPPPPPPLPP 2429
Score = 37.0 bits (84), Expect = 0.080
Identities = 21/47 (44%), Positives = 24/47 (51%), Gaps = 4/47 (8%)
Query: 3 PPPFMPPPGIPPPFPPMGLPPMSQRPPAIPPMPPGILPPMLPPMGAP 49
PPP PPP PPP PP PP+ PP P P ILP + +P
Sbjct: 2406 PPPPPPPPPPPPPPPPPPPPPL---PPPTSPKPT-ILPKKKLTVASP 2448
Score = 36.6 bits (83), Expect = 0.10
Identities = 14/27 (51%), Positives = 16/27 (59%)
Query: 187 PQTLQPQPPQPQPDPPPVPPGPTPVPT 213
P P PP P P PPP+PP +P PT
Sbjct: 2410 PPPPPPPPPPPPPPPPPLPPPTSPKPT 2436
Score = 34.7 bits (78), Expect = 0.39
Identities = 81/385 (21%), Positives = 128/385 (33%), Gaps = 70/385 (18%)
Query: 3 PPPFMPPPGIPPPFPPMGLPPMSQRP-----------PAIPPMPPG------------IL 39
PPP P P P P P P SQ+P PA P +
Sbjct: 509 PPPQQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQSTKPVSQTGSGKPLQ 568
Query: 40 PPMLPPMGAPPPLTQIPGMVPPMM-PGMLMPAVPVTA--ATAPGADTASSAVAGTGPPRA 96
PP + P PP +P + P+ L+ VP A T T ++ G P
Sbjct: 569 PPTVSPSAKQPPSQGLPKTICPLCNTTELLLHVPEKANFNTCTECQTTVCSLCGFNP--- 625
Query: 97 LWSEHVAPDGRIYYYNADDKQSVWEKPSVLKSKAELLLSQCPWKEYKSDTGKPYYYNNQS 156
+ H+ N K+++ + + S + L P + + S
Sbjct: 626 --NPHLTEVKEWLCLNCQMKRALGGDLAPVPSSPQPKLKTAPVTTTSA-------VSKSS 676
Query: 157 KESRWTRPKDLDDLEVLVKQEAAGKQQ-QQLPQTLQPQPPQPQP---DPPPVPPGPTPVP 212
+ + T P K++AA KQ + P+ +P P QP P P
Sbjct: 677 PQPQQTSP----------KKDAAPKQDLSKAPEPKKPPPLVKQPTLHGSPSAKAKQPPEA 726
Query: 213 TGLLEPEPGGSEDCDVLEATQPLEQGFLQQLEEGPSSSGQHQP-----QQEEEESKPEPE 267
L +P P E + P EQ ++ P +P +KP+
Sbjct: 727 DSLSKPAP-------PKEPSVPSEQDKAPVADDKPKQPKMVKPTTDLVSSSSATTKPDIP 779
Query: 268 RSGLSWSNREKAKQAFKELLRDKAVPSNASWEQAMKMVVTDPRYSALPK-LSEKKQAFNA 326
S + EK K D A PS + K+ D + A+P+ S+ K +
Sbjct: 780 SSKVQSQAEEKTTPPLK---TDSAKPSQSFPPTGEKVSPFDSK--AIPRPASDSKIISHP 834
Query: 327 YKAQREKEEKEEARLRAKEAKQTLQ 351
+ K +K+ ++ KE + Q
Sbjct: 835 GPSSESKGQKQVDPVQKKEEPKKAQ 859
Score = 33.5 bits (75), Expect = 0.88
Identities = 14/27 (51%), Positives = 14/27 (51%)
Query: 184 QQLPQTLQPQPPQPQPDPPPVPPGPTP 210
Q P P PP P P PPP PP P P
Sbjct: 2404 QPPPPPPPPPPPPPPPPPPPPPPLPPP 2430
Score = 32.3 bits (72), Expect = 2.0
Identities = 25/92 (27%), Positives = 27/92 (29%), Gaps = 15/92 (16%)
Query: 3 PPPFMPPPGIPPPFP---PMGLPPMSQRPPAIPPMPPGI------------LPPMLPPMG 47
P P PG+ P P P P IP G P LP
Sbjct: 418 PKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQLPGPA 477
Query: 48 APPPLTQIPGMVPPMMPGMLMPAVPVTAATAP 79
PPP P PP PG P +T P
Sbjct: 478 KPPPQQPGPAKPPPQQPGSAKPPSQQPGSTKP 509
Score = 32.0 bits (71), Expect = 2.6
Identities = 13/26 (50%), Positives = 14/26 (53%)
Query: 187 PQTLQPQPPQPQPDPPPVPPGPTPVP 212
P P PP P P PPP P PT +P
Sbjct: 2414 PPPPPPPPPPPPPLPPPTSPKPTILP 2439
Score = 32.0 bits (71), Expect = 2.6
Identities = 13/23 (56%), Positives = 17/23 (73%), Gaps = 3/23 (13%)
Query: 201 PPPVPPGPTPVPTGLL---EPEP 220
PPPVPP P+ +P+GL+ PEP
Sbjct: 2483 PPPVPPKPSSIPSGLVFTHRPEP 2505
Score = 30.4 bits (67), Expect = 7.4
Identities = 13/25 (52%), Positives = 13/25 (52%)
Query: 196 QPQPDPPPVPPGPTPVPTGLLEPEP 220
QP P PPP PP P P P P P
Sbjct: 2404 QPPPPPPPPPPPPPPPPPPPPPPLP 2428
>gi|55749531 splicing factor 3B subunit 2 [Homo sapiens]
Length = 895
Score = 59.3 bits (142), Expect = 1e-08
Identities = 118/543 (21%), Positives = 198/543 (36%), Gaps = 124/543 (22%)
Query: 3 PPPFMPP-PGIPPPFPPMGLPPMSQRPPAIPPMPPGI---LPPMLPP-MGAPPPLTQIPG 57
PPP PGIP P PP+GLPP+ Q PP PP PPG+ P PP +G PPPL
Sbjct: 80 PPPMSAQLPGIPMPPPPLGLPPL-QPPPPPPPPPPGLGLGFPMAHPPNLGPPPPLR---- 134
Query: 58 MVPPMMPGMLMPAVPVTAATAPGADTASSAVAGTGPPRALWSEHVAPDGRIYYYNADDKQ 117
G P AL E
Sbjct: 135 ---------------------------------VGEPVALSEE----------------- 144
Query: 118 SVWEKPSVLKSKAELLLSQCPWKEYKSDTG-KPYYYNNQSKESRWTRPKDLDDLEVLVKQ 176
E+ + + +A LL+ Q + + D K + Q K + ++ E+
Sbjct: 145 ---ERLKLAQQQAALLMQQEERAKQQGDHSLKEHELLEQQKRAAVLLEQERQQ-EIAKMG 200
Query: 177 EAAGKQQQQLPQTLQPQPPQPQPDPPPVPPGPTP--VPTGLLEPEPGG--------SEDC 226
+ Q + Q P P+ P P GPTP +P G P P G + +
Sbjct: 201 TPVPRPPQDMGQIGVRTPLGPRVAAPVGPVGPTPTVLPMGAPVPRPRGPPPPPGDENREM 260
Query: 227 DVLEATQPLEQGFLQQLEEGPSSSGQHQPQQEEEE-----------SKPEPERSGLSWSN 275
D + Q + L+ S + QQEEEE S E E +S S
Sbjct: 261 DDPSVGPKIPQALEKILQLKESRQEEMNSQQEEEEMETDARSSLGQSASETEEDTVSVSK 320
Query: 276 REK-----AKQAFKELLRDKAVPSNASWEQAMKMV----------------VTDPRYSAL 314
+EK ++ K+ R + V S +S ++ VT+
Sbjct: 321 KEKNRKRRNRKKKKKPQRVRGVSSESSGDREKDSTRSRGSDSPAADVEIEYVTEEPEIYE 380
Query: 315 PKLSEKKQAFNAYKAQ---REKEEKEEARLRAKE--AKQTLQHFLEQHERMTSTTRYRRA 369
P K+ F A+K ++++EKE +L E A + F E+H+ +
Sbjct: 381 PNFIFFKRIFEAFKLTDDVKKEKEKEPEKLDKLENSAAPKKKGFEEEHKDSDDDSSDDEQ 440
Query: 370 EQTFGELEVWAVVPERDRKEVYDDVLFFLAKKEKEQAKQLRRRNIQALKSILDGMSSVNF 429
E+ ++ R + ++ +A+ + + + ++ + L + +SV
Sbjct: 441 EKKPEAPKLSKKKLRRMNRFTVAELKQLVARPDVVEMHDVTAQDPKLLVHLKATRNSVPV 500
Query: 430 QTTWSQAQQYL-----MDNPSFAQDHQLQNMDKEDALICFEEHIRALEREEEEERERARL 484
W ++YL ++ P F +L + K + +E AL+ +EE++ ++++
Sbjct: 501 PRHWCFKRKYLQGKRGIEKPPF----ELPDFIKRTGI---QEMREALQEKEEQKTMKSKM 553
Query: 485 RER 487
RE+
Sbjct: 554 REK 556
>gi|156766047 GRB10 interacting GYF protein 2 isoform c [Homo
sapiens]
Length = 1293
Score = 57.8 bits (138), Expect = 4e-08
Identities = 83/361 (22%), Positives = 150/361 (41%), Gaps = 55/361 (15%)
Query: 171 EVLVKQEAAG---KQQQQLP------QTLQPQPPQPQPDPPPVPPGPTPVPTGLLEPEP- 220
+VL +Q+ A +QQQQL QTL+ + P P + E +P
Sbjct: 632 QVLAQQQKAALSSQQQQQLALLLQQFQTLKMRISDQNIIPSVTRSVSVPDTGSIWELQPT 691
Query: 221 --------GGSEDCDVLEATQP---LEQGFLQQLEEGPSSSGQHQPQQEEEESKPEPERS 269
GGS L+ T P LEQ LQQLE+ ++ + + ++ E +K E E
Sbjct: 692 ASQPTVWEGGSVWDLPLDTTTPGPALEQ--LQQLEKAKAAKLEQERREAEMRAKREEEER 749
Query: 270 GLSWSNREKAKQAFKELLRDKAVPSNASWEQAMKMVVTDPRYSALPKLSEKKQAFNAYKA 329
+E+ ++ +E+LR + E+ + + + AL + E++ A +
Sbjct: 750 ----KRQEELRRQQEEILRRQQEEERKRREE--EELARRKQEEALRRQREQEIALRRQRE 803
Query: 330 QREKEEKEEARLRAKEAKQTLQHFLEQHERMTSTTRYRRAEQTFGELEVWAVVPERDRKE 389
+ E++++EEA R +E ++ E+ ER R+ E+ E WA E ++
Sbjct: 804 EEERQQQEEALRRLEERRR------EEEERRKQEELLRKQEE---EAAKWAREEEEAQRR 854
Query: 390 VYDDVLFFLAKKEKEQAKQLRRRNIQALKSILDGMSSVNFQTTWSQAQQYLMDNPSFAQD 449
+ ++ L + +E+A +LR + + L+ Q Q+ L Q
Sbjct: 855 LEENRL-----RMEEEAARLRHEEEERKRKELEVQRQKELMRQRQQQQEALRRLQQQQQQ 909
Query: 450 HQLQNM---------DKEDALICFEE---HIRALEREEEEERERARLRERRQQRKNREAF 497
QL M + + C + + +++ EEE + R +RRQQR+ +A
Sbjct: 910 QQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKLEEERERQLREEQRRQQRELMKAL 969
Query: 498 Q 498
Q
Sbjct: 970 Q 970
Score = 38.9 bits (89), Expect = 0.021
Identities = 63/269 (23%), Positives = 109/269 (40%), Gaps = 38/269 (14%)
Query: 608 LEKAEAREREREKEEARRMRRREAAFRSMLRQAVPALELGTAWEEVRERFVCDSAFEQIT 667
LEKA+A + E+E+ EA +RE R RQ EL EE+ R
Sbjct: 723 LEKAKAAKLEQERREAEMRAKREEEERK--RQE----ELRRQQEEILRR----------Q 766
Query: 668 LESERIRLFREFLQVLEQTECQHLHTKGRKHGRKGKKHHHKRSHSPSGSESEEEELPPPS 727
E ER R E L +Q E + R+ + E EE + +
Sbjct: 767 QEEERKRREEEELARRKQEEALRRQREQEIALRRQR-------------EEEERQQQEEA 813
Query: 728 LRPPKRRRRNPSESGSEPSSSLDSVESGGAALGGRGSPSSHLLGADHGLRKAK-----KP 782
LR + RRR E + L + AA R + ++ LR + +
Sbjct: 814 LRRLEERRREEEERRKQ--EELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRH 871
Query: 783 KKKTKKRRHKSNSPESETDPEEKAGKESDEKEQEQDKDRELQQAELPNRSPGFGIKKEKT 842
+++ +KR+ + E + + +E+ + Q+Q + ++L Q +LP+ S +G + T
Sbjct: 872 EEEERKRKELEVQRQKELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSSST-WGQQSNTT 930
Query: 843 GWDTSESELSEGELERRRRTLLQQLDDHQ 871
S++ LS E+++ +QL + Q
Sbjct: 931 ACQ-SQATLSLAEIQKLEEERERQLREEQ 958
Score = 37.4 bits (85), Expect = 0.061
Identities = 52/265 (19%), Positives = 104/265 (39%), Gaps = 8/265 (3%)
Query: 607 LLEKAEAREREREKEEARRMRRREAAFRSMLRQAVPALELGTAWEEVRERFVCDSAFEQI 666
+L + + ER+R +EE R++E A R Q + AL EE +++ E+
Sbjct: 762 ILRRQQEEERKRREEEELARRKQEEALRRQREQEI-ALRRQREEEERQQQEEALRRLEER 820
Query: 667 TLESERIRLFREFLQVLEQTECQHLHTKGRKHGRKGKKHHHKRSHSPSGSESEEEELPPP 726
E E R E L+ E+ E + + R+ +++ + + EEEE
Sbjct: 821 RREEEERRKQEELLRKQEE-EAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRK 879
Query: 727 SLRPPKRRRRNPSESGSEPSSSLDSVESGGAALGGRGSPSSHLLGADHGLRKAKKPKKKT 786
L +++ + + + L PSS G +++ ++
Sbjct: 880 ELEVQRQKELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSSSTWG-----QQSNTTACQS 934
Query: 787 KKRRHKSNSPESETDPEEKAGKESDEKEQEQDKDRELQQAELPNRSPGFGIKKEKTGWDT 846
+ + + E + E + +E +++E K + QQ + + G+G + +G
Sbjct: 935 QATLSLAEIQKLEEERERQLREEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTK 994
Query: 847 SESELSEGELERRRRTLLQQLDDHQ 871
S E+ + E R+ + QQ HQ
Sbjct: 995 SLLEIQQEE-ARQMQKQQQQQQQHQ 1018
Score = 34.7 bits (78), Expect = 0.39
Identities = 19/34 (55%), Positives = 21/34 (61%), Gaps = 1/34 (2%)
Query: 170 LEVLVKQEA-AGKQQQQLPQTLQPQPPQPQPDPP 202
LE KQ+A +QQQQLPQ Q QPPQ P P
Sbjct: 1186 LERRAKQKANQQRQQQQLPQQQQQQPPQQPPQQP 1219
Score = 33.9 bits (76), Expect = 0.67
Identities = 32/141 (22%), Positives = 66/141 (46%), Gaps = 17/141 (12%)
Query: 230 EATQPLEQGFLQQLEEGPSSSGQHQPQQEEEESKPEPERSGLSWSNREKAKQAFKEL--- 286
EA + LE+ L+ EE ++ ++E + + E +R R++ ++A + L
Sbjct: 850 EAQRRLEENRLRMEEE---AARLRHEEEERKRKELEVQRQKELMRQRQQQQEALRRLQQQ 906
Query: 287 -----LRDKAVPSNASWEQAMKMVVTDPRYSALPKLSEKKQAFNAYKAQREKEEKEEARL 341
L +PS+++W Q T + A L+E ++ + +RE++ +EE R
Sbjct: 907 QQQQQLAQMKLPSSSTWGQQSN--TTACQSQATLSLAEIQKL----EEERERQLREEQRR 960
Query: 342 RAKEAKQTLQHFLEQHERMTS 362
+ +E + LQ +Q ++ S
Sbjct: 961 QQRELMKALQQQQQQQQQKLS 981
Score = 32.7 bits (73), Expect = 1.5
Identities = 42/195 (21%), Positives = 80/195 (41%), Gaps = 16/195 (8%)
Query: 678 EFLQVLEQTECQHLHTKGRKHGRKGKKHHHKRSHSPSGSESEEEELPPPSLRPPKRRRRN 737
E LQ LE+ + L + R+ + K+ +R ++EE+ ++RR
Sbjct: 718 EQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEE-LRRQQEEILRRQQEEERKRREE 776
Query: 738 PSESGSEPSSSLDSVESGGAALGGRGSPSSHLLGADHGLRKAKKPKKKTKKRRHKSNSPE 797
+ + +L AL R + LR+ ++ +++ ++RR + E
Sbjct: 777 EELARRKQEEALRRQREQEIAL-RRQREEEERQQQEEALRRLEERRREEEERRKQE---E 832
Query: 798 SETDPEEKAGKESDEKEQEQDKDRELQQAELPNRSPGFGIKKEKTGWDTSESELSEGELE 857
EE+A K + E+E+ Q R L++ L ++ E E E ELE
Sbjct: 833 LLRKQEEEAAKWAREEEEAQ---RRLEENRLRMEEEAARLRHE-------EEERKRKELE 882
Query: 858 -RRRRTLLQQLDDHQ 871
+R++ L++Q Q
Sbjct: 883 VQRQKELMRQRQQQQ 897
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.312 0.130 0.379
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 43,930,262
Number of Sequences: 37866
Number of extensions: 2896547
Number of successful extensions: 64854
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 865
Number of HSP's successfully gapped in prelim test: 1648
Number of HSP's that attempted gapping in prelim test: 23542
Number of HSP's gapped (non-prelim): 25351
length of query: 871
length of database: 18,247,518
effective HSP length: 111
effective length of query: 760
effective length of database: 14,044,392
effective search space: 10673737920
effective search space used: 10673737920
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.