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Search of human proteins with 71773010
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|71773010 adaptor-related protein complex 1, gamma 1 subunit
isoform a [Homo sapiens]
(825 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|71773010 adaptor-related protein complex 1, gamma 1 subunit i... 1620 0.0
gi|71772942 adaptor-related protein complex 1, gamma 1 subunit i... 1608 0.0
gi|4503843 adaptor-related protein complex 1, gamma 2 subunit [H... 936 0.0
gi|19913414 adaptor-related protein complex 2, alpha 1 subunit i... 274 3e-73
gi|19913416 adaptor-related protein complex 2, alpha 1 subunit i... 274 3e-73
gi|27477041 adaptor-related protein complex 2, alpha 2 subunit [... 273 4e-73
gi|37675283 adaptor-related protein complex 4, epsilon 1 subunit... 234 3e-61
gi|117553580 adaptor-related protein complex 3, delta 1 subunit ... 167 3e-41
gi|117553584 adaptor-related protein complex 3, delta 1 subunit ... 96 2e-19
gi|9558729 golgi associated, gamma adaptin ear containing, ARF b... 92 2e-18
gi|48527952 golgi associated, gamma adaptin ear containing, ARF ... 92 2e-18
gi|22027653 adaptor-related protein complex 1 beta 1 subunit iso... 92 3e-18
gi|22027651 adaptor-related protein complex 1 beta 1 subunit iso... 91 6e-18
gi|9558751 ADP-ribosylation factor binding protein 2 [Homo sapiens] 79 2e-14
gi|14719400 ADP-ribosylation factor binding protein 3 isoform sh... 78 4e-14
gi|20336267 ADP-ribosylation factor binding protein 3 isoform lo... 78 4e-14
gi|71773106 adaptor-related protein complex 2, beta 1 subunit is... 76 1e-13
gi|239758145 PREDICTED: similar to ADP-ribosylation factor bindi... 75 2e-13
gi|4557469 adaptor-related protein complex 2, beta 1 subunit iso... 74 4e-13
gi|109134349 coatomer protein complex, subunit gamma 2 [Homo sap... 61 4e-09
gi|221316632 coatomer protein complex, subunit beta 1 [Homo sapi... 55 3e-07
gi|221316630 coatomer protein complex, subunit beta 1 [Homo sapi... 55 3e-07
gi|7705369 coatomer protein complex, subunit beta 1 [Homo sapiens] 55 3e-07
gi|32484979 adaptor-related protein complex 3, beta 1 subunit [H... 54 8e-07
gi|11559929 coatomer protein complex, subunit gamma 1 [Homo sapi... 52 2e-06
gi|166197671 adaptor-related protein complex 4, beta 1 subunit [... 42 0.003
gi|31324577 molecule interacting with Rab13 [Homo sapiens] 40 0.012
gi|241982780 programmed cell death 6 interacting protein isoform... 38 0.044
gi|22027538 programmed cell death 6 interacting protein isoform ... 38 0.044
gi|153792780 additional sex combs like 2 [Homo sapiens] 38 0.044
>gi|71773010 adaptor-related protein complex 1, gamma 1 subunit
isoform a [Homo sapiens]
Length = 825
Score = 1620 bits (4194), Expect = 0.0
Identities = 825/825 (100%), Positives = 825/825 (100%)
Query: 1 MPAPIRLRELIRTIRTARTQAEEREMIQKECAAIRSSFREEDNTYRCRNVAKLLYMHMLG 60
MPAPIRLRELIRTIRTARTQAEEREMIQKECAAIRSSFREEDNTYRCRNVAKLLYMHMLG
Sbjct: 1 MPAPIRLRELIRTIRTARTQAEEREMIQKECAAIRSSFREEDNTYRCRNVAKLLYMHMLG 60
Query: 61 YPAHFGQLECLKLIASQKFTDKRIGYLGAMLLLDERQDVHLLMTNCIKNDLNHSTQFVQG 120
YPAHFGQLECLKLIASQKFTDKRIGYLGAMLLLDERQDVHLLMTNCIKNDLNHSTQFVQG
Sbjct: 61 YPAHFGQLECLKLIASQKFTDKRIGYLGAMLLLDERQDVHLLMTNCIKNDLNHSTQFVQG 120
Query: 121 LALCTLGCMGSSEMCRDLAGEVEKLLKTSNSYLRKKAALCAVHVIRKVPELMEMFLPATK 180
LALCTLGCMGSSEMCRDLAGEVEKLLKTSNSYLRKKAALCAVHVIRKVPELMEMFLPATK
Sbjct: 121 LALCTLGCMGSSEMCRDLAGEVEKLLKTSNSYLRKKAALCAVHVIRKVPELMEMFLPATK 180
Query: 181 NLLNEKNHGVLHTSVVLLTEMCERSPDMLAHFRKNEKLVPQLVRILKNLIMSGYSPEHDV 240
NLLNEKNHGVLHTSVVLLTEMCERSPDMLAHFRKNEKLVPQLVRILKNLIMSGYSPEHDV
Sbjct: 181 NLLNEKNHGVLHTSVVLLTEMCERSPDMLAHFRKNEKLVPQLVRILKNLIMSGYSPEHDV 240
Query: 241 SGISDPFLQVRILRLLRILGRNDDDSSEAMNDILAQVATNTETSKNVGNAILYETVLTIM 300
SGISDPFLQVRILRLLRILGRNDDDSSEAMNDILAQVATNTETSKNVGNAILYETVLTIM
Sbjct: 241 SGISDPFLQVRILRLLRILGRNDDDSSEAMNDILAQVATNTETSKNVGNAILYETVLTIM 300
Query: 301 DIKSESGLRVLAINILGRFLLNNDKNIRYVALTSLLKTVQTDHNAVQRHRSTIVDCLKDL 360
DIKSESGLRVLAINILGRFLLNNDKNIRYVALTSLLKTVQTDHNAVQRHRSTIVDCLKDL
Sbjct: 301 DIKSESGLRVLAINILGRFLLNNDKNIRYVALTSLLKTVQTDHNAVQRHRSTIVDCLKDL 360
Query: 361 DVSIKRRAMELSFALVNGNNIRGMMKELLYFLDSCEPEFKADCASGIFLAAEKYAPSKRW 420
DVSIKRRAMELSFALVNGNNIRGMMKELLYFLDSCEPEFKADCASGIFLAAEKYAPSKRW
Sbjct: 361 DVSIKRRAMELSFALVNGNNIRGMMKELLYFLDSCEPEFKADCASGIFLAAEKYAPSKRW 420
Query: 421 HIDTIMRVLTTAGSYVRDDAVPNLIQLITNSVEMHAYTVQRLYKAILGDYSQQPLVQVAA 480
HIDTIMRVLTTAGSYVRDDAVPNLIQLITNSVEMHAYTVQRLYKAILGDYSQQPLVQVAA
Sbjct: 421 HIDTIMRVLTTAGSYVRDDAVPNLIQLITNSVEMHAYTVQRLYKAILGDYSQQPLVQVAA 480
Query: 481 WCIGEYGDLLVSGQCEEEEPIQVTEDEVLDILESVLISNMSTSVTRGYALTAIMKLSTRF 540
WCIGEYGDLLVSGQCEEEEPIQVTEDEVLDILESVLISNMSTSVTRGYALTAIMKLSTRF
Sbjct: 481 WCIGEYGDLLVSGQCEEEEPIQVTEDEVLDILESVLISNMSTSVTRGYALTAIMKLSTRF 540
Query: 541 TCTVNRIKKVVSIYGSSIDVELQQRAVEYNALFKKYDHMRSALLERMPVMEKVTTNGPTE 600
TCTVNRIKKVVSIYGSSIDVELQQRAVEYNALFKKYDHMRSALLERMPVMEKVTTNGPTE
Sbjct: 541 TCTVNRIKKVVSIYGSSIDVELQQRAVEYNALFKKYDHMRSALLERMPVMEKVTTNGPTE 600
Query: 601 IVQTNGETEPAPLETKPPPSGPQPTSQANDLLDLLGGNDITPVIPTAPTSKPSSAGGELL 660
IVQTNGETEPAPLETKPPPSGPQPTSQANDLLDLLGGNDITPVIPTAPTSKPSSAGGELL
Sbjct: 601 IVQTNGETEPAPLETKPPPSGPQPTSQANDLLDLLGGNDITPVIPTAPTSKPSSAGGELL 660
Query: 661 DLLGDINLTGAPAAAPAPASVPQISQPPFLLDGLSSQPLFNDIAAGIPSITAYSKNGLKI 720
DLLGDINLTGAPAAAPAPASVPQISQPPFLLDGLSSQPLFNDIAAGIPSITAYSKNGLKI
Sbjct: 661 DLLGDINLTGAPAAAPAPASVPQISQPPFLLDGLSSQPLFNDIAAGIPSITAYSKNGLKI 720
Query: 721 EFTFERSNTNPSVTVITIQASNSTELDMTDFVFQAAVPKTFQLQLLSPSSSIVPAFNTGT 780
EFTFERSNTNPSVTVITIQASNSTELDMTDFVFQAAVPKTFQLQLLSPSSSIVPAFNTGT
Sbjct: 721 EFTFERSNTNPSVTVITIQASNSTELDMTDFVFQAAVPKTFQLQLLSPSSSIVPAFNTGT 780
Query: 781 ITQVIKVLNPQKQQLRMRIKLTYNHKGSAMQDLAEVNNFPPQSWQ 825
ITQVIKVLNPQKQQLRMRIKLTYNHKGSAMQDLAEVNNFPPQSWQ
Sbjct: 781 ITQVIKVLNPQKQQLRMRIKLTYNHKGSAMQDLAEVNNFPPQSWQ 825
>gi|71772942 adaptor-related protein complex 1, gamma 1 subunit
isoform b [Homo sapiens]
Length = 822
Score = 1608 bits (4164), Expect = 0.0
Identities = 822/825 (99%), Positives = 822/825 (99%), Gaps = 3/825 (0%)
Query: 1 MPAPIRLRELIRTIRTARTQAEEREMIQKECAAIRSSFREEDNTYRCRNVAKLLYMHMLG 60
MPAPIRLRELIRTIRTARTQAEEREMIQKECAAIRSSFREEDNTYRCRNVAKLLYMHMLG
Sbjct: 1 MPAPIRLRELIRTIRTARTQAEEREMIQKECAAIRSSFREEDNTYRCRNVAKLLYMHMLG 60
Query: 61 YPAHFGQLECLKLIASQKFTDKRIGYLGAMLLLDERQDVHLLMTNCIKNDLNHSTQFVQG 120
YPAHFGQLECLKLIASQKFTDKRIGYLGAMLLLDERQDVHLLMTNCIKNDLNHSTQFVQG
Sbjct: 61 YPAHFGQLECLKLIASQKFTDKRIGYLGAMLLLDERQDVHLLMTNCIKNDLNHSTQFVQG 120
Query: 121 LALCTLGCMGSSEMCRDLAGEVEKLLKTSNSYLRKKAALCAVHVIRKVPELMEMFLPATK 180
LALCTLGCMGSSEMCRDLAGEVEKLLKTSNSYLRKKAALCAVHVIRKVPELMEMFLPATK
Sbjct: 121 LALCTLGCMGSSEMCRDLAGEVEKLLKTSNSYLRKKAALCAVHVIRKVPELMEMFLPATK 180
Query: 181 NLLNEKNHGVLHTSVVLLTEMCERSPDMLAHFRKNEKLVPQLVRILKNLIMSGYSPEHDV 240
NLLNEKNHGVLHTSVVLLTEMCERSPDMLAHFRK LVPQLVRILKNLIMSGYSPEHDV
Sbjct: 181 NLLNEKNHGVLHTSVVLLTEMCERSPDMLAHFRK---LVPQLVRILKNLIMSGYSPEHDV 237
Query: 241 SGISDPFLQVRILRLLRILGRNDDDSSEAMNDILAQVATNTETSKNVGNAILYETVLTIM 300
SGISDPFLQVRILRLLRILGRNDDDSSEAMNDILAQVATNTETSKNVGNAILYETVLTIM
Sbjct: 238 SGISDPFLQVRILRLLRILGRNDDDSSEAMNDILAQVATNTETSKNVGNAILYETVLTIM 297
Query: 301 DIKSESGLRVLAINILGRFLLNNDKNIRYVALTSLLKTVQTDHNAVQRHRSTIVDCLKDL 360
DIKSESGLRVLAINILGRFLLNNDKNIRYVALTSLLKTVQTDHNAVQRHRSTIVDCLKDL
Sbjct: 298 DIKSESGLRVLAINILGRFLLNNDKNIRYVALTSLLKTVQTDHNAVQRHRSTIVDCLKDL 357
Query: 361 DVSIKRRAMELSFALVNGNNIRGMMKELLYFLDSCEPEFKADCASGIFLAAEKYAPSKRW 420
DVSIKRRAMELSFALVNGNNIRGMMKELLYFLDSCEPEFKADCASGIFLAAEKYAPSKRW
Sbjct: 358 DVSIKRRAMELSFALVNGNNIRGMMKELLYFLDSCEPEFKADCASGIFLAAEKYAPSKRW 417
Query: 421 HIDTIMRVLTTAGSYVRDDAVPNLIQLITNSVEMHAYTVQRLYKAILGDYSQQPLVQVAA 480
HIDTIMRVLTTAGSYVRDDAVPNLIQLITNSVEMHAYTVQRLYKAILGDYSQQPLVQVAA
Sbjct: 418 HIDTIMRVLTTAGSYVRDDAVPNLIQLITNSVEMHAYTVQRLYKAILGDYSQQPLVQVAA 477
Query: 481 WCIGEYGDLLVSGQCEEEEPIQVTEDEVLDILESVLISNMSTSVTRGYALTAIMKLSTRF 540
WCIGEYGDLLVSGQCEEEEPIQVTEDEVLDILESVLISNMSTSVTRGYALTAIMKLSTRF
Sbjct: 478 WCIGEYGDLLVSGQCEEEEPIQVTEDEVLDILESVLISNMSTSVTRGYALTAIMKLSTRF 537
Query: 541 TCTVNRIKKVVSIYGSSIDVELQQRAVEYNALFKKYDHMRSALLERMPVMEKVTTNGPTE 600
TCTVNRIKKVVSIYGSSIDVELQQRAVEYNALFKKYDHMRSALLERMPVMEKVTTNGPTE
Sbjct: 538 TCTVNRIKKVVSIYGSSIDVELQQRAVEYNALFKKYDHMRSALLERMPVMEKVTTNGPTE 597
Query: 601 IVQTNGETEPAPLETKPPPSGPQPTSQANDLLDLLGGNDITPVIPTAPTSKPSSAGGELL 660
IVQTNGETEPAPLETKPPPSGPQPTSQANDLLDLLGGNDITPVIPTAPTSKPSSAGGELL
Sbjct: 598 IVQTNGETEPAPLETKPPPSGPQPTSQANDLLDLLGGNDITPVIPTAPTSKPSSAGGELL 657
Query: 661 DLLGDINLTGAPAAAPAPASVPQISQPPFLLDGLSSQPLFNDIAAGIPSITAYSKNGLKI 720
DLLGDINLTGAPAAAPAPASVPQISQPPFLLDGLSSQPLFNDIAAGIPSITAYSKNGLKI
Sbjct: 658 DLLGDINLTGAPAAAPAPASVPQISQPPFLLDGLSSQPLFNDIAAGIPSITAYSKNGLKI 717
Query: 721 EFTFERSNTNPSVTVITIQASNSTELDMTDFVFQAAVPKTFQLQLLSPSSSIVPAFNTGT 780
EFTFERSNTNPSVTVITIQASNSTELDMTDFVFQAAVPKTFQLQLLSPSSSIVPAFNTGT
Sbjct: 718 EFTFERSNTNPSVTVITIQASNSTELDMTDFVFQAAVPKTFQLQLLSPSSSIVPAFNTGT 777
Query: 781 ITQVIKVLNPQKQQLRMRIKLTYNHKGSAMQDLAEVNNFPPQSWQ 825
ITQVIKVLNPQKQQLRMRIKLTYNHKGSAMQDLAEVNNFPPQSWQ
Sbjct: 778 ITQVIKVLNPQKQQLRMRIKLTYNHKGSAMQDLAEVNNFPPQSWQ 822
>gi|4503843 adaptor-related protein complex 1, gamma 2 subunit [Homo
sapiens]
Length = 785
Score = 936 bits (2419), Expect = 0.0
Identities = 490/824 (59%), Positives = 619/824 (75%), Gaps = 47/824 (5%)
Query: 5 IRLRELIRTIRTARTQAEEREMIQKECAAIRSSFREEDNTYRCRNVAKLLYMHMLGYPAH 64
++L++LI IR A+TQA+ERE+IQKECA IR+SFR+ D +R R +AKLLY+HMLGYPAH
Sbjct: 6 LKLQDLIEEIRGAKTQAQEREVIQKECAHIRASFRDGDPVHRHRQLAKLLYVHMLGYPAH 65
Query: 65 FGQLECLKLIASQKFTDKRIGYLGAMLLLDERQDVHLLMTNCIKNDLNHSTQFVQGLALC 124
FGQ+ECLKLIAS +FTDKR+GYLGAMLLLDER D HLL+TN IKNDL+ Q VQGLALC
Sbjct: 66 FGQMECLKLIASSRFTDKRVGYLGAMLLLDERHDAHLLITNSIKNDLSQGIQPVQGLALC 125
Query: 125 TLGCMGSSEMCRDLAGEVEKLLKTSNSYLRKKAALCAVHVIRKVPELMEMFLPATKNLLN 184
TL MGS+EMCRDLA EVEKLL + Y+RKKA L AVH+IRKVPEL +FLP LL+
Sbjct: 126 TLSTMGSAEMCRDLAPEVEKLLLQPSPYVRKKAILTAVHMIRKVPELSSVFLPPCAQLLH 185
Query: 185 EKNHGVLHTSVVLLTEMCERSPDMLAHFRKNEKLVPQLVRILKNLIMSGYSPEHDVSGIS 244
E++HG+L ++ L+TE+CERSP L HFRK +VPQLV IL+ L+ GYS EH +SG+S
Sbjct: 186 ERHHGILLGTITLITELCERSPAALRHFRK---VVPQLVHILRTLVTMGYSTEHSISGVS 242
Query: 245 DPFLQVRILRLLRILGRNDDDSSEAMNDILAQVATNTETSKNVGNAILYETVLTIMDIKS 304
DPFLQV+ILRLLRILGRN ++SSE MND+LAQVATNT+TS+N GNA+L+ETVLTIMDI+S
Sbjct: 243 DPFLQVQILRLLRILGRNHEESSETMNDLLAQVATNTDTSRNAGNAVLFETVLTIMDIRS 302
Query: 305 ESGLRVLAINILGRFLLNNDKNIRYVALTSLLKTVQTDHNAVQRHRSTIVDCLKDLDVSI 364
+GLRVLA+NILGRFLLN+D+NIRYVALTSLL+ VQ+DH+AVQRHR T+V+CL++ D S+
Sbjct: 303 AAGLRVLAVNILGRFLLNSDRNIRYVALTSLLRLVQSDHSAVQRHRPTVVECLRETDASL 362
Query: 365 KRRAMELSFALVNGNNIRGMMKELLYFLDSCEPEFKADCASGIFLAAEKYAPSKRWHIDT 424
RRA+ELS ALVN +N+R MM+EL FL+SC P+ +ADCASGI LAAE++AP+KRWHIDT
Sbjct: 363 SRRALELSLALVNSSNVRAMMQELQAFLESCPPDLRADCASGILLAAERFAPTKRWHIDT 422
Query: 425 IMRVLTTAGSYVRDDAVPNLIQLITNSVEMHAYTVQRLYKAILGDYSQQPLVQVAAWCIG 484
I+ VLTTAG++VRDDAV NL QLI + E+HAY+V+RLY A+ D SQQPLVQVAAWCIG
Sbjct: 423 ILHVLTTAGTHVRDDAVANLTQLIGGAQELHAYSVRRLYNALAEDISQQPLVQVAAWCIG 482
Query: 485 EYGDLLVSGQCEEEEPIQVTEDEVLDILESVLISNMSTSVTRGYALTAIMKLSTRFTCTV 544
EYGDLL++G CEE EP+QV E+EVL +LE VL S+MS TRGYALTA+MKLSTR
Sbjct: 483 EYGDLLLAGNCEEIEPLQVDEEEVLALLEKVLQSHMSLPATRGYALTALMKLSTRLCGDN 542
Query: 545 NRIKKVVSIYGSSIDVELQQRAVEYNALFKKYDHMRSALLERMPVMEKVTTNGPTEIVQT 604
NRI++VVSIYGS +DVELQQRAVEY+ LF+KYDHMR+A+LE+MP++E+ +GP +
Sbjct: 543 NRIRQVVSIYGSCLDVELQQRAVEYDTLFRKYDHMRAAILEKMPLVER---DGPQADEEA 599
Query: 605 NGETEPAPL-ETKPPPSGPQPTSQANDLLDLLGG--NDITPVIPTAPTSKPSSAGGELLD 661
E A L E P P+ PQ SQ DLLDLL G D+ P S GG L+
Sbjct: 600 KESKEAAQLSEAAPVPTEPQ-ASQLLDLLDLLDGASGDV-----QHPPHLDPSPGGALVH 653
Query: 662 LLGDINLTGAPAAAPAPASVPQISQPPFLLDGLSSQPLFNDIAAGIPSITAYSKNGLKIE 721
LL +P + PP A IP + + + G+++
Sbjct: 654 LL----------------DLPCVPPPP----------------APIPDLKVFEREGVQLN 681
Query: 722 FTFERSNTNPSVTVITIQASNSTELDMTDFVFQAAVPKTFQLQLLSPSSSIVPAFNTGTI 781
+F R NP++ +ITI A+N +E D+T F+ QAAVPK+ QLQL +PS + VPA I
Sbjct: 682 LSFIRPPENPALLLITITATNFSEGDVTHFICQAAVPKSLQLQLQAPSGNTVPARGGLPI 741
Query: 782 TQVIKVLNPQKQQLRMRIKLTYNHKGSAMQDLAEVNNFPPQSWQ 825
TQ+ ++LNP K LR++++LTY+H ++Q++ EVNN P +SWQ
Sbjct: 742 TQLFRILNPNKAPLRLKLRLTYDHFHQSVQEIFEVNNLPVESWQ 785
>gi|19913414 adaptor-related protein complex 2, alpha 1 subunit
isoform 1 [Homo sapiens]
Length = 977
Score = 274 bits (700), Expect = 3e-73
Identities = 210/717 (29%), Positives = 371/717 (51%), Gaps = 61/717 (8%)
Query: 7 LRELIRTIRTARTQAEEREMIQKECAAIRSSFREE---DNTYRCRNVAKLLYMHMLGYPA 63
L I IR +++ E + I KE A IRS F+ + D + + V KLL++ +LG+
Sbjct: 13 LAVFISDIRNCKSKEAEIKRINKELANIRSKFKGDKALDGYSKKKYVCKLLFIFLLGHDI 72
Query: 64 HFGQLECLKLIASQKFTDKRIGYLGAMLLLDERQDVHLLMTNCIKNDLNHSTQFVQGLAL 123
FG +E + L++S K+T+K+IGYL +L++ ++ L+ N IKNDL LAL
Sbjct: 73 DFGHMEAVNLLSSNKYTEKQIGYLFISVLVNSNSELIRLINNAIKNDLASRNPTFMCLAL 132
Query: 124 CTLGCMGSSEMCRDLAGEVEKLLKTSNSY--LRKKAALCAVHVIRKVPELMEM--FLPAT 179
+ +GS EM A ++ ++L +S +++ AALC + + + P+L+ M +
Sbjct: 133 HCIANVGSREMGEAFAADIPRILVAGDSMDSVKQSAALCLLRLYKASPDLVPMGEWTARV 192
Query: 180 KNLLNEKNHGVLHTSVVLLTEMCERSPDMLAHFRKNEKLVPQLVRILKNLIMSGYSPEHD 239
+LLN+++ GV+ +V L+T +C+++PD + V V L ++ S + D
Sbjct: 193 VHLLNDQHMGVVTAAVSLITCLCKKNPDDF------KTCVSLAVSRLSRIVSSASTDLQD 246
Query: 240 VSG--ISDPFLQVRILRLLRILGRNDDDSS-----EAMNDILAQVATNTETSK----NVG 288
+ + P+L V++LRLL+ +D + E + +L + ++ K N
Sbjct: 247 YTYYFVPAPWLSVKLLRLLQCYPPPEDAAVKGRLVECLETVLNKAQEPPKSKKVQHSNAK 306
Query: 289 NAILYETVLTIMDIKSESGLRVLAINILGRFLLNNDKNIRYVALTSL--LKTVQTDHNAV 346
NAIL+ET+ I+ SE L V A N LG+FL + + N+RY+AL S+ L + + H AV
Sbjct: 307 NAILFETISLIIHYDSEPNLLVRACNQLGQFLQHRETNLRYLALESMCTLASSEFSHEAV 366
Query: 347 QRHRSTIVDCLK-DLDVSIKRRAMELSFALVNGNNIRGMMKELLYFLDSCEPEFKADCAS 405
+ H T+++ LK + DVS+++RA +L +A+ + +N + ++ E+L +L++ + + +
Sbjct: 367 KTHIDTVINALKTERDVSVRQRAADLLYAMCDRSNAKQIVSEMLRYLETADYAIREEIVL 426
Query: 406 GIFLAAEKYAPSKRWHIDTIMRVLTTAGSYVRDDAVPNLIQLITNSVEMHAYTVQRLYKA 465
+ + AEKYA W++DTI+ ++ AG YV ++ ++Q++TN ++ Y + +++A
Sbjct: 427 KVAILAEKYAVDYSWYVDTILNLIRIAGDYVSEEVWYRVLQIVTNRDDVQGYAAKTVFEA 486
Query: 466 ILGDYSQQPLVQVAAWCIGEYGDLLVSGQCEEEEPIQVTEDEVLDILESVLISNMSTSVT 525
+ + +V+V + +GE+G+ L++G P+Q +L S ++ + T
Sbjct: 487 LQAPACHENMVKVGGYILGEFGN-LIAGDPRSSPPVQ------FSLLHSKF--HLCSVAT 537
Query: 526 RGYALTAIMKLSTRFTCTVNRIKKVVSIYGSSI---DVELQQRAVEYNALFK-KYDHMRS 581
R L+ +K F T I+ V+ GS + DVELQQRAVEY L + +
Sbjct: 538 RALLLSTYIKFINLFPETKATIQGVLRA-GSQLRNADVELQQRAVEYLTLSSVASTDVLA 596
Query: 582 ALLERMPVMEKVTTNGPTEIVQTNGETEPAPLETKPPPSGPQPTSQANDLLDLLGGNDIT 641
+LE MP + ++ ++ + G + L+ P+S D+ GG + T
Sbjct: 597 TVLEEMPPFPERESSILAKLKRKKGPGAGSALD----DGRRDPSSN-----DINGGMEPT 647
Query: 642 PVIPTAPTSKPSSAGGELLDLLGDINLTGAPAAAPAPASVPQISQPPFLLDGLSSQP 698
P T T PS+ DLLG L AP A PAS + + DG ++QP
Sbjct: 648 P--STVSTPSPSA------DLLG---LRAAPPPAAPPASAGAGNLLVDVFDGPAAQP 693
>gi|19913416 adaptor-related protein complex 2, alpha 1 subunit
isoform 2 [Homo sapiens]
Length = 955
Score = 274 bits (700), Expect = 3e-73
Identities = 210/717 (29%), Positives = 371/717 (51%), Gaps = 61/717 (8%)
Query: 7 LRELIRTIRTARTQAEEREMIQKECAAIRSSFREE---DNTYRCRNVAKLLYMHMLGYPA 63
L I IR +++ E + I KE A IRS F+ + D + + V KLL++ +LG+
Sbjct: 13 LAVFISDIRNCKSKEAEIKRINKELANIRSKFKGDKALDGYSKKKYVCKLLFIFLLGHDI 72
Query: 64 HFGQLECLKLIASQKFTDKRIGYLGAMLLLDERQDVHLLMTNCIKNDLNHSTQFVQGLAL 123
FG +E + L++S K+T+K+IGYL +L++ ++ L+ N IKNDL LAL
Sbjct: 73 DFGHMEAVNLLSSNKYTEKQIGYLFISVLVNSNSELIRLINNAIKNDLASRNPTFMCLAL 132
Query: 124 CTLGCMGSSEMCRDLAGEVEKLLKTSNSY--LRKKAALCAVHVIRKVPELMEM--FLPAT 179
+ +GS EM A ++ ++L +S +++ AALC + + + P+L+ M +
Sbjct: 133 HCIANVGSREMGEAFAADIPRILVAGDSMDSVKQSAALCLLRLYKASPDLVPMGEWTARV 192
Query: 180 KNLLNEKNHGVLHTSVVLLTEMCERSPDMLAHFRKNEKLVPQLVRILKNLIMSGYSPEHD 239
+LLN+++ GV+ +V L+T +C+++PD + V V L ++ S + D
Sbjct: 193 VHLLNDQHMGVVTAAVSLITCLCKKNPDDF------KTCVSLAVSRLSRIVSSASTDLQD 246
Query: 240 VSG--ISDPFLQVRILRLLRILGRNDDDSS-----EAMNDILAQVATNTETSK----NVG 288
+ + P+L V++LRLL+ +D + E + +L + ++ K N
Sbjct: 247 YTYYFVPAPWLSVKLLRLLQCYPPPEDAAVKGRLVECLETVLNKAQEPPKSKKVQHSNAK 306
Query: 289 NAILYETVLTIMDIKSESGLRVLAINILGRFLLNNDKNIRYVALTSL--LKTVQTDHNAV 346
NAIL+ET+ I+ SE L V A N LG+FL + + N+RY+AL S+ L + + H AV
Sbjct: 307 NAILFETISLIIHYDSEPNLLVRACNQLGQFLQHRETNLRYLALESMCTLASSEFSHEAV 366
Query: 347 QRHRSTIVDCLK-DLDVSIKRRAMELSFALVNGNNIRGMMKELLYFLDSCEPEFKADCAS 405
+ H T+++ LK + DVS+++RA +L +A+ + +N + ++ E+L +L++ + + +
Sbjct: 367 KTHIDTVINALKTERDVSVRQRAADLLYAMCDRSNAKQIVSEMLRYLETADYAIREEIVL 426
Query: 406 GIFLAAEKYAPSKRWHIDTIMRVLTTAGSYVRDDAVPNLIQLITNSVEMHAYTVQRLYKA 465
+ + AEKYA W++DTI+ ++ AG YV ++ ++Q++TN ++ Y + +++A
Sbjct: 427 KVAILAEKYAVDYSWYVDTILNLIRIAGDYVSEEVWYRVLQIVTNRDDVQGYAAKTVFEA 486
Query: 466 ILGDYSQQPLVQVAAWCIGEYGDLLVSGQCEEEEPIQVTEDEVLDILESVLISNMSTSVT 525
+ + +V+V + +GE+G+ L++G P+Q +L S ++ + T
Sbjct: 487 LQAPACHENMVKVGGYILGEFGN-LIAGDPRSSPPVQ------FSLLHSKF--HLCSVAT 537
Query: 526 RGYALTAIMKLSTRFTCTVNRIKKVVSIYGSSI---DVELQQRAVEYNALFK-KYDHMRS 581
R L+ +K F T I+ V+ GS + DVELQQRAVEY L + +
Sbjct: 538 RALLLSTYIKFINLFPETKATIQGVLRA-GSQLRNADVELQQRAVEYLTLSSVASTDVLA 596
Query: 582 ALLERMPVMEKVTTNGPTEIVQTNGETEPAPLETKPPPSGPQPTSQANDLLDLLGGNDIT 641
+LE MP + ++ ++ + G + L+ P+S D+ GG + T
Sbjct: 597 TVLEEMPPFPERESSILAKLKRKKGPGAGSALD----DGRRDPSSN-----DINGGMEPT 647
Query: 642 PVIPTAPTSKPSSAGGELLDLLGDINLTGAPAAAPAPASVPQISQPPFLLDGLSSQP 698
P T T PS+ DLLG L AP A PAS + + DG ++QP
Sbjct: 648 P--STVSTPSPSA------DLLG---LRAAPPPAAPPASAGAGNLLVDVFDGPAAQP 693
>gi|27477041 adaptor-related protein complex 2, alpha 2 subunit
[Homo sapiens]
Length = 939
Score = 273 bits (699), Expect = 4e-73
Identities = 214/718 (29%), Positives = 364/718 (50%), Gaps = 72/718 (10%)
Query: 7 LRELIRTIRTARTQAEEREMIQKECAAIRSSFREE---DNTYRCRNVAKLLYMHMLGYPA 63
L I IR +++ E + I KE A IRS F+ + D + + V KLL++ +LG+
Sbjct: 13 LAVFISDIRNCKSKEAEIKRINKELANIRSKFKGDKALDGYSKKKYVCKLLFIFLLGHDI 72
Query: 64 HFGQLECLKLIASQKFTDKRIGYLGAMLLLDERQDVHLLMTNCIKNDLNHSTQFVQGLAL 123
FG +E + L++S ++T+K+IGYL +L++ ++ L+ N IKNDL GLAL
Sbjct: 73 DFGHMEAVNLLSSNRYTEKQIGYLFISVLVNSNSELIRLINNAIKNDLASRNPTFMGLAL 132
Query: 124 CTLGCMGSSEMCRDLAGEVEKLLKTSNSY--LRKKAALCAVHVIRKVPELMEM--FLPAT 179
+ +GS EM AGE+ K+L ++ +++ AALC + + R P+L+ M +
Sbjct: 133 HCIASVGSREMAEAFAGEIPKVLVAGDTMDSVKQSAALCLLRLYRTSPDLVPMGDWTSRV 192
Query: 180 KNLLNEKNHGVLHTSVVLLTEMCERSPDMLAHFRKNEKLVPQLVRILKNLIMSGYSPEHD 239
+LLN+++ GV+ + L+T + +++P+ F+ + L V L ++ S + D
Sbjct: 193 VHLLNDQHLGVVTAATSLITTLAQKNPE---EFKTSVSLA---VSRLSRIVTSASTDLQD 246
Query: 240 VSG--ISDPFLQVRILRLLRILGRNDDDS----SEAMNDILAQVATNTETSK----NVGN 289
+ + P+L V++LRLL+ D +E + IL + ++ K N N
Sbjct: 247 YTYYFVPAPWLSVKLLRLLQCYPPPDPAVRGRLTECLETILNKAQEPPKSKKVQHSNAKN 306
Query: 290 AILYETVLTIMDIKSESGLRVLAINILGRFLLNNDKNIRYVALTSL--LKTVQTDHNAVQ 347
A+L+E + I+ SE L V A N LG+FL + + N+RY+AL S+ L + + H AV+
Sbjct: 307 AVLFEAISLIIHHDSEPNLLVRACNQLGQFLQHRETNLRYLALESMCTLASSEFSHEAVK 366
Query: 348 RHRSTIVDCLK-DLDVSIKRRAMELSFALVNGNNIRGMMKELLYFLDSCEPEFKADCASG 406
H T+++ LK + DVS+++RA++L +A+ + +N ++ E+L +L++ + + +
Sbjct: 367 THIETVINALKTERDVSVRQRAVDLLYAMCDRSNAPQIVAEMLSYLETADYSIREEIVLK 426
Query: 407 IFLAAEKYAPSKRWHIDTIMRVLTTAGSYVRDDAVPNLIQLITNSVEMHAYTVQRLYKAI 466
+ + AEKYA W++DTI+ ++ AG YV ++ +IQ++ N ++ Y + +++A+
Sbjct: 427 VAILAEKYAVDYTWYVDTILNLIRIAGDYVSEEVWYRVIQIVINRDDVQGYAAKTVFEAL 486
Query: 467 LGDYSQQPLVQVAAWCIGEYGDLLVSGQCEEEEPIQVTEDEVLDILESVLISNMSTSVTR 526
+ LV+V + +GE+G+ L++G IQ +L S ++ + TR
Sbjct: 487 QAPACHENLVKVGGYILGEFGN-LIAGDPRSSPLIQ------FHLLHSKF--HLCSVPTR 537
Query: 527 GYALTAIMKLSTRFTCTVNRIKKVVSIYGS--SIDVELQQRAVEYNAL--FKKYDHMRSA 582
L+ +K F I+ V+ + DVELQQRAVEY L D + +
Sbjct: 538 ALLLSTYIKFVNLFPEVKPTIQDVLRSDSQLRNADVELQQRAVEYLRLSTVASTDILATV 597
Query: 583 LLERMPVMEKVTT--------NGPTEI-----------VQTNGETEPAPLETKPPPSGPQ 623
L E P E+ ++ GP+ + V NG EPAP T S P
Sbjct: 598 LEEMPPFPERESSILAKLKKKKGPSTVTDLEDTKRDRSVDVNGGPEPAPASTS-AVSTPS 656
Query: 624 PTSQANDLLDLLGGNDITPVIPTAPTSKPSSAGGELLDLLGDINLTGAPAAAP-APAS 680
P++ DLLG P AP P S+GG LL D+ A AP AP S
Sbjct: 657 PSA------DLLG----LGAAPPAPAGPPPSSGGS--GLLVDVFSDSASVVAPLAPGS 702
>gi|37675283 adaptor-related protein complex 4, epsilon 1 subunit
[Homo sapiens]
Length = 1137
Score = 234 bits (596), Expect = 3e-61
Identities = 162/591 (27%), Positives = 293/591 (49%), Gaps = 31/591 (5%)
Query: 6 RLRELIRTIRTARTQAEEREMIQKECAAIRSSFREEDNTYRCRN--VAKLLYMHMLGYPA 63
RL L+R I ++ EE ++IQ+E ++++++ T + + +L+Y MLGY A
Sbjct: 35 RLGSLVRGITALTSKHEEEKLIQQELSSLKATVSAPTTTLKMMKECMVRLIYCEMLGYDA 94
Query: 64 HFGQLECLKLIASQKFTDKRIGYLGAMLLLDERQDVHLLMTNCIKNDLNHSTQFVQGLAL 123
FG + +KL +KR+GYL L L E ++ LL+ N + DL + +AL
Sbjct: 95 SFGYIHAIKLAQQGNLLEKRVGYLAVSLFLHESHELLLLLVNTVVKDLQSTNLVEVCMAL 154
Query: 124 CTLGCMGSSEMCRDLAGEVEKLLKTSNSYLRKKAALCAVHVIRKVPELMEMFLPATKNLL 183
+ + EM + +E L+ S +R+KA L P ++ + L
Sbjct: 155 TVVSQIFPCEMIPAVLPLIEDKLQHSKEIVRRKAVLALYKFHLIAPNQVQHIHIKFRKAL 214
Query: 184 NEKNHGVLHTSVVLLTEMCERSPDMLAHFRKNEKLVPQLVRILKNLIMSGYSPEHDVSGI 243
+++ GV+ S+ + M + + + L V ILK ++ E + +
Sbjct: 215 CDRDVGVMAASLHIYLRMIKENSSGY------KDLTGSFVTILKQVVGGKLPVEFNYHSV 268
Query: 244 SDPFLQVRILRLLRILGRNDDDSSEAMNDILAQVATNTETSKNVGNAILYETVLTIMDIK 303
P+LQ+++LR+L +LG++D +SE M D+L + E + NV AIL+E V T+ I
Sbjct: 269 PAPWLQIQLLRILGLLGKDDQRTSELMYDVLDESLRRAELNHNVTYAILFECVHTVYSIY 328
Query: 304 SESGLRVLAINILGRFLLNNDKNIRYVALTSLLKTVQTDHNAVQRHRSTIVDCLKDLDVS 363
+S L A +G+F+L+ N++Y+ L +L +Q D +H+ TI++CL D
Sbjct: 329 PKSELLEKAAKCIGKFVLSPKINLKYLGLKALTYVIQQDPTLALQHQMTIIECLDHPDPI 388
Query: 364 IKRRAMELSFALVNGNNIRGMMKELLYFLDSCEPEFK-ADCASGIFLAAEKYAPSKRWHI 422
IKR +EL + + N NI +++++L +L + E+ + I AEKYAP W I
Sbjct: 389 IKRETLELLYRITNAQNITVIVQKMLEYLHQSKEEYVIVNLVGKIAELAEKYAPDNAWFI 448
Query: 423 DTIMRVLTTAGSYVRDDAVPNLIQLI-------TNSVEMHAYTVQRLYKAIL---GDYSQ 472
T+ V + G + D N ++L+ T ++ Y VQ Y +L +
Sbjct: 449 QTMNAVFSVGGDVMHPDIPNNFLRLLAEGFDDETEDQQLRLYAVQS-YLTLLDMENVFYP 507
Query: 473 QPLVQVAAWCIGEYGDLLVSGQCEEEEPIQVTEDEVLDILESVLISNMSTSVTRGYALTA 532
Q +QV +W +GEY LL ++E P +EV+ L +L+++ +S T+ + + A
Sbjct: 508 QRFLQVMSWVLGEYSYLL-----DKETP-----EEVIAKLYKLLMNDSVSSETKAWLIAA 557
Query: 533 IMKLSTRFTCTVNRIKKVVSIYGSSIDVELQQRAVEYNALFKKYDHMRSAL 583
+ KL+++ + N +++++ + S+D ++Q A E L + + M+S L
Sbjct: 558 VTKLTSQ-AHSSNTVERLIHEFTISLDTCMRQHAFELKHLHENVELMKSLL 607
>gi|117553580 adaptor-related protein complex 3, delta 1 subunit
isoform 2 [Homo sapiens]
Length = 1153
Score = 167 bits (424), Expect = 3e-41
Identities = 158/699 (22%), Positives = 303/699 (43%), Gaps = 96/699 (13%)
Query: 7 LRELIRTIRTARTQAEEREMIQKECAAIRSSFREEDNTYRCRNVAKLLYMHMLGYPAHFG 66
L++L+R IR + +E + I + I+ ++++ + V KL Y+ MLGY +
Sbjct: 18 LQDLVRGIRNHKE--DEAKYISQCIDEIKQELKQDNIAVKANAVCKLTYLQMLGYDISWA 75
Query: 67 QLECLKLIASQKFTDKRIGYLGAMLLLDERQDVHLLMTNCIKNDLNHSTQFVQGLALCTL 126
++++++ KFT KRIGYL A E DV +L TN I+ DL+ +Q+ G+AL L
Sbjct: 76 AFNIIEVMSASKFTFKRIGYLAASQSFHEGTDVIMLTTNQIRKDLSSPSQYDTGVALTGL 135
Query: 127 GCMGSSEMCRDLAGEVEKLLKTSNSYLRKKAALCAVHVIRKVPELMEMFLPATKNLLNEK 186
C + ++ RDLA ++ L+ + Y+RKKA L V K PE + P K L +
Sbjct: 136 SCFVTPDLARDLANDIMTLMSHTKPYIRKKAVLIMYKVFLKYPESLRPAFPRLKEKLEDP 195
Query: 187 NHGVLHTSVVLLTEMCERSPDMLAHFRKNEKLVPQLVRILKNLIMSGYSPEHDVSGISDP 246
+ GV +V ++ E+ R+P + L P +++ + ++
Sbjct: 196 DPGVQSAAVNVICELARRNP------KNYLSLAPLFFKLM--------------TSSTNN 235
Query: 247 FLQVRILRLLRILGRNDDDSSEAMNDILAQVATNTETSKNVGNAILYETVLTIMDI---- 302
++ ++I++L L + + + + L + +T ++LYE V T++ +
Sbjct: 236 WVLIKIIKLFGALTPLEPRLGKKLIEPLTNLIHSTSAM-----SLLYECVNTVIAVLISL 290
Query: 303 ----KSESGLRVLAINILGRFLLNNDKNIRYVALTSLLKTVQTDHNAVQRHRSTIVDCLK 358
+ S L + L + ++D+N++Y+ L ++ K ++T +VQ H+ I+ CL
Sbjct: 291 SSGMPNHSASIQLCVQKLRILIEDSDQNLKYLGLLAMSKILKTHPKSVQSHKDLILQCLD 350
Query: 359 DLDVSIKRRAMELSFALVNGNNIRGMMKELLYFLDSCEPEFKAD---------CASGIFL 409
D D SI+ RA++L + +V+ N+ ++K+L+ +D E D C+ +
Sbjct: 351 DKDESIRLRALDLLYGMVSKKNLMEIVKKLMTHVDKAEGTTYRDELLTKIIDICSQSNY- 409
Query: 410 AAEKYAPSKRWHIDTIMRVLTTAGSYVRDDAVPNLIQLITNSVEMHAYTVQRLYKA---- 465
+Y + W+I ++ + G+ ++ + + + V ++
Sbjct: 410 ---QYITNFEWYISILVELTRLEGTRHGHLIAAQMLDVAIRVKAIRKFAVSQMSALLDSA 466
Query: 466 -ILGDYSQQ----PLVQVAAWCIGEYGDLLVSGQCEEEEPIQ------------VTEDEV 508
+L +Q+ ++ AAW GE+ + L E ++ V V
Sbjct: 467 HLLASSTQRNGICEVLYAAAWICGEFSEHLQEPHHTLEAMLRPRVTTLPGHIQAVYVQNV 526
Query: 509 LDILESVLISNMSTSVTRG-YALTAIMKLSTRFTCTVNRIKKVVSIYGSSIDVELQQRAV 567
+ + S+L G A+T +M V+R+ + V S D+E+Q+RA
Sbjct: 527 VKLYASILQQKEQAGEAEGAQAVTQLM---------VDRLPQFV----QSADLEVQERA- 572
Query: 568 EYNALFKKYDHMRSALLERMPVMEKVTTNGPTEIVQTNGETEPAPLETKPPPSGPQPTSQ 627
+ + + H++ + +PV E+V+ E+ P + P P G +
Sbjct: 573 --SCILQLVKHIQKLQAKDVPVAEEVSALFAGEL----NPVAPKAQKKVPVPEGLDLDAW 626
Query: 628 ANDLLDLLGGNDITPVI------PTAPTSKPSSAGGELL 660
N+ L D P P +PS A E L
Sbjct: 627 INEPLSDSESEDERPRAVFHEEEQRRPKHRPSEADEEEL 665
>gi|117553584 adaptor-related protein complex 3, delta 1 subunit
isoform 1 [Homo sapiens]
Length = 1112
Score = 95.5 bits (236), Expect = 2e-19
Identities = 52/153 (33%), Positives = 87/153 (56%), Gaps = 2/153 (1%)
Query: 7 LRELIRTIRTARTQAEEREMIQKECAAIRSSFREEDNTYRCRNVAKLLYMHMLGYPAHFG 66
L++L+R IR + +E + I + I+ ++++ + V KL Y+ MLGY +
Sbjct: 18 LQDLVRGIRNHKE--DEAKYISQCIDEIKQELKQDNIAVKANAVCKLTYLQMLGYDISWA 75
Query: 67 QLECLKLIASQKFTDKRIGYLGAMLLLDERQDVHLLMTNCIKNDLNHSTQFVQGLALCTL 126
++++++ KFT KRIGYL A E DV +L TN I+ DL+ +Q+ G+AL L
Sbjct: 76 AFNIIEVMSASKFTFKRIGYLAASQSFHEGTDVIMLTTNQIRKDLSSPSQYDTGVALTGL 135
Query: 127 GCMGSSEMCRDLAGEVEKLLKTSNSYLRKKAAL 159
C + ++ RDLA ++ L+ + Y+RKKA L
Sbjct: 136 SCFVTPDLARDLANDIMTLMSHTKPYIRKKAKL 168
Score = 69.7 bits (169), Expect = 1e-11
Identities = 86/416 (20%), Positives = 169/416 (40%), Gaps = 69/416 (16%)
Query: 290 AILYETVLTIMDI--------KSESGLRVLAINILGRFLLNNDKNIRYVALTSLLKTVQT 341
++LYE V T++ + + S L + L + ++D+N++Y+ L ++ K ++T
Sbjct: 183 SLLYECVNTVIAVLISLSSGMPNHSASIQLCVQKLRILIEDSDQNLKYLGLLAMSKILKT 242
Query: 342 DHNAVQRHRSTIVDCLKDLDVSIKRRAMELSFALVNGNNIRGMMKELLYFLDSCEPEFKA 401
+VQ H+ I+ CL D D SI+ RA++L + +V+ N+ ++K+L+ +D E
Sbjct: 243 HPKSVQSHKDLILQCLDDKDESIRLRALDLLYGMVSKKNLMEIVKKLMTHVDKAEGTTYR 302
Query: 402 D---------CASGIFLAAEKYAPSKRWHIDTIMRVLTTAGSYVRDDAVPNLIQLITNSV 452
D C+ + +Y + W+I ++ + G+ ++ +
Sbjct: 303 DELLTKIIDICSQSNY----QYITNFEWYISILVELTRLEGTRHGHLIAAQMLDVAIRVK 358
Query: 453 EMHAYTVQRLYKA-----ILGDYSQQ----PLVQVAAWCIGEYGDLLVSGQCEEEEPIQ- 502
+ + V ++ +L +Q+ ++ AAW GE+ + L E ++
Sbjct: 359 AIRKFAVSQMSALLDSAHLLASSTQRNGICEVLYAAAWICGEFSEHLQEPHHTLEAMLRP 418
Query: 503 -----------VTEDEVLDILESVLISNMSTSVTRG-YALTAIMKLSTRFTCTVNRIKKV 550
V V+ + S+L G A+T +M V+R+ +
Sbjct: 419 RVTTLPGHIQAVYVQNVVKLYASILQQKEQAGEAEGAQAVTQLM---------VDRLPQF 469
Query: 551 VSIYGSSIDVELQQRAVEYNALFKKYDHMRSALLERMPVMEKVTTNGPTEIVQTNGETEP 610
V S D+E+Q+RA + + + H++ + +PV E+V+ E+ P
Sbjct: 470 V----QSADLEVQERA---SCILQLVKHIQKLQAKDVPVAEEVSALFAGEL----NPVAP 518
Query: 611 APLETKPPPSGPQPTSQANDLLDLLGGNDITPVI------PTAPTSKPSSAGGELL 660
+ P P G + N+ L D P P +PS A E L
Sbjct: 519 KAQKKVPVPEGLDLDAWINEPLSDSESEDERPRAVFHEEEQRRPKHRPSEADEEEL 574
>gi|9558729 golgi associated, gamma adaptin ear containing, ARF
binding protein 1 isoform 1 [Homo sapiens]
Length = 639
Score = 92.0 bits (227), Expect = 2e-18
Identities = 72/251 (28%), Positives = 118/251 (47%), Gaps = 29/251 (11%)
Query: 603 QTNGETEP-------AP-LETKPPPSGPQPTSQANDLLDLLGGNDITPVIPTAPTS---- 650
Q++ TEP AP +E++PP P S D LDLLG + +P
Sbjct: 386 QSSDATEPPAPALAQAPSMESRPPAQTSLPASSGLDDLDLLGKTLLQQSLPPESQQVRWE 445
Query: 651 -KPSSAGGELLDLLGDINLTGAPAAA---------PAPASVPQISQPPFLLDGLSSQPLF 700
+ + L DL + +P+++ P P PQ P L + PL
Sbjct: 446 KQQPTPRLTLRDLQNKSSSCSSPSSSATSLLHTVSPEPPRPPQQPVPTELSLASITVPLE 505
Query: 701 NDIAAGIPSITAYSKNGLKIEFTFERSNT--NPSVTVITIQASNSTELDMTDFVFQAAVP 758
+ + I +T Y ++G +I F F R V V+ + ++ + + VFQ+AVP
Sbjct: 506 SIKPSNILPVTVYDQHGFRILFHFARDPLPGRSDVLVVVVSMLSTAPQPIRNIVFQSAVP 565
Query: 759 KTFQLQLLSPSSSIVPAFNT----GTITQVIKVLNPQKQQLRMRIKLTYNHKGSAMQDLA 814
K +++L PS + +PAFN ITQV+ + NPQK+++R+R KLT+ ++
Sbjct: 566 KVMKVKLQPPSGTELPAFNPIVHPSAITQVLLLANPQKEKVRLRYKLTFTMGDQTYNEMG 625
Query: 815 EVNNF-PPQSW 824
+V+ F PP++W
Sbjct: 626 DVDQFPPPETW 636
>gi|48527952 golgi associated, gamma adaptin ear containing, ARF
binding protein 1 isoform 2 [Homo sapiens]
Length = 552
Score = 92.0 bits (227), Expect = 2e-18
Identities = 72/251 (28%), Positives = 118/251 (47%), Gaps = 29/251 (11%)
Query: 603 QTNGETEP-------AP-LETKPPPSGPQPTSQANDLLDLLGGNDITPVIPTAPTS---- 650
Q++ TEP AP +E++PP P S D LDLLG + +P
Sbjct: 299 QSSDATEPPAPALAQAPSMESRPPAQTSLPASSGLDDLDLLGKTLLQQSLPPESQQVRWE 358
Query: 651 -KPSSAGGELLDLLGDINLTGAPAAA---------PAPASVPQISQPPFLLDGLSSQPLF 700
+ + L DL + +P+++ P P PQ P L + PL
Sbjct: 359 KQQPTPRLTLRDLQNKSSSCSSPSSSATSLLHTVSPEPPRPPQQPVPTELSLASITVPLE 418
Query: 701 NDIAAGIPSITAYSKNGLKIEFTFERSNT--NPSVTVITIQASNSTELDMTDFVFQAAVP 758
+ + I +T Y ++G +I F F R V V+ + ++ + + VFQ+AVP
Sbjct: 419 SIKPSNILPVTVYDQHGFRILFHFARDPLPGRSDVLVVVVSMLSTAPQPIRNIVFQSAVP 478
Query: 759 KTFQLQLLSPSSSIVPAFNT----GTITQVIKVLNPQKQQLRMRIKLTYNHKGSAMQDLA 814
K +++L PS + +PAFN ITQV+ + NPQK+++R+R KLT+ ++
Sbjct: 479 KVMKVKLQPPSGTELPAFNPIVHPSAITQVLLLANPQKEKVRLRYKLTFTMGDQTYNEMG 538
Query: 815 EVNNF-PPQSW 824
+V+ F PP++W
Sbjct: 539 DVDQFPPPETW 549
>gi|22027653 adaptor-related protein complex 1 beta 1 subunit
isoform b [Homo sapiens]
Length = 942
Score = 91.7 bits (226), Expect = 3e-18
Identities = 178/802 (22%), Positives = 320/802 (39%), Gaps = 130/802 (16%)
Query: 82 KRIGYLGAMLLLDERQDVHLLMTNCIKNDLNHSTQFVQGLALCTLGCMGSSEMCRDLAGE 141
K++ YL M + D+ ++ N D ++ LA+ T+GC+ ++ L
Sbjct: 66 KKLVYLYLMNYAKSQPDMAIMAVNTFVKDCEDPNPLIRALAVRTMGCIRVDKITEYLCEP 125
Query: 142 VEKLLKTSNSYLRKKAALCAVHVIRKVPELME--MFLPATKNLLNEKNHGVLHTSVVLLT 199
+ K LK + Y+RK AA+C + +L+E FL K+L+++ N V+ +V L+
Sbjct: 126 LRKCLKDEDPYVRKTAAVCVAKLHDINAQLVEDQGFLDTLKDLISDSNPMVVANAVAALS 185
Query: 200 EMCERSPDMLAHFRKNEKLVPQLVRILKNLIMSGYSPEHDVSGISDPFLQVRILRLLRIL 259
E+ E P N + + +L+ L G Q+ IL L
Sbjct: 186 EIAESHPSSNL-LDLNPQSINKLLTALNECTEWG---------------QIFILDCLANY 229
Query: 260 GRNDDDSSEAMNDILAQVATNTETSKNVGNAILYETVLTIMDIKSE------SGLRVLAI 313
DD +++ I +V + + + ++ M++ S+ + L+ LA
Sbjct: 230 MPKDDREAQS---ICERVTPRLSHANSAVVLSAVKVLMKFMEMLSKDLDYYGTLLKKLAP 286
Query: 314 NILGRFLLNNDKNIRYVALTSLLKTVQTDHNAVQRHRSTIVDCLKDLDVSIKRRAMELSF 373
++ LL+ + ++YVAL ++ VQ + +H + + + +K +++
Sbjct: 287 PLV--TLLSAEPELQYVALRNINLIVQ-KRPEILKHEMKVFFVKYNDPIYVKLEKLDIMI 343
Query: 374 ALVNGNNIRGMMKELLYFLDSCEPEFKADCASGIFLAAEKYAPSKRWHIDTIMRVLTTAG 433
L + NI ++ EL + + +F I A K S + T++ ++ T
Sbjct: 344 RLASQANIAQVLAELKEYATEVDVDFVRKAVRAIGRCAIKVEQSAERCVSTLLDLIQTKV 403
Query: 434 SYVRDDAVPNLIQLITNSVEMHAYTVQRLYKAILGDYSQQPLVQVA-AWCIGEYGDLLVS 492
+YV +A+ + + + + L + + D +P + A W +GEY + +
Sbjct: 404 NYVVQEAIVVIKDIFRKYPNKYESVIATLCENL--DSLDEPEARAAMIWIVGEYAERI-- 459
Query: 493 GQCEEEEPIQVTEDEVLDILESVL--ISNMSTSVTRGYALTAIMKLSTRF-TCTVNRIKK 549
D ++LES L + ST V + LTAI+KL + T T +++
Sbjct: 460 -------------DNADELLESFLEGFHDESTQV-QLQLLTAIVKLFLKKPTETQELVQQ 505
Query: 550 VVSIYGSSID-VELQQRAVEYNALF-------------------KKYDHMRSALLERM-- 587
V+S+ D +L+ R Y L ++ D + LL+ +
Sbjct: 506 VLSLATQDSDNPDLRDRGYIYWRLLSTDPVAAKEVVLAEKPLISEETDLIEPTLLDELIC 565
Query: 588 --PVMEKVTTNGPTEIVQ--------------TNGETEPAPLETKP--PPSGPQP--TSQ 627
+ V P+ V+ + E+ +P ET P P G QP
Sbjct: 566 YIGTLASVYHKPPSAFVEGGRGVVHKSLPPRTASSESAESP-ETAPTGAPPGEQPDVIPA 624
Query: 628 ANDLLDLLGGNDITPVIPTAPTSKPSSAGGELLDLLG---DINLTGAPAAAPAPASVPQI 684
DLL L D+ P + P + S G +DLLG D + G AP A+VP
Sbjct: 625 QGDLLGDLLNLDLGPPVSGPPLATSSVQMG-AVDLLGGGLDSLIGGTNFVAPPTAAVPAN 683
Query: 685 SQPPFLLDGLSSQPLFNDIAAGIPSIT------------AYSKNGLKIEFTFERSNTNPS 732
P G LF D+ +G+ +++ A GL+I TF R + S
Sbjct: 684 LGAPI---GSGLSDLF-DLTSGVGTLSGSYVAPKAVWLPAMKAKGLEISGTFTRQVGSIS 739
Query: 733 VTVITIQASNSTELDMTDFVFQ------AAVPKTFQLQL---LSPSSSIVPAFNTGTITQ 783
+ +Q +N MTDF Q P T LQ+ LSP+ ++ + T+
Sbjct: 740 ---MDLQLTNKALQVMTDFAIQFNRNSFGLAPAT-PLQVHAPLSPNQTVEISLPLSTVGS 795
Query: 784 VIKV--LNPQKQQLRMRIKLTY 803
V+K+ LN + ++ I + Y
Sbjct: 796 VMKMEPLNNLQVAVKNNIDVFY 817
>gi|22027651 adaptor-related protein complex 1 beta 1 subunit
isoform a [Homo sapiens]
Length = 949
Score = 90.5 bits (223), Expect = 6e-18
Identities = 180/808 (22%), Positives = 322/808 (39%), Gaps = 135/808 (16%)
Query: 82 KRIGYLGAMLLLDERQDVHLLMTNCIKNDLNHSTQFVQGLALCTLGCMGSSEMCRDLAGE 141
K++ YL M + D+ ++ N D ++ LA+ T+GC+ ++ L
Sbjct: 66 KKLVYLYLMNYAKSQPDMAIMAVNTFVKDCEDPNPLIRALAVRTMGCIRVDKITEYLCEP 125
Query: 142 VEKLLKTSNSYLRKKAALCAVHVIRKVPELME--MFLPATKNLLNEKNHGVLHTSVVLLT 199
+ K LK + Y+RK AA+C + +L+E FL K+L+++ N V+ +V L+
Sbjct: 126 LRKCLKDEDPYVRKTAAVCVAKLHDINAQLVEDQGFLDTLKDLISDSNPMVVANAVAALS 185
Query: 200 EMCERSPDMLAHFRKNEKLVPQLVRILKNLIMSGYSPEHDVSGISDPFLQVRILRLLRIL 259
E+ E P N + + +L+ L G Q+ IL L
Sbjct: 186 EIAESHPSSNL-LDLNPQSINKLLTALNECTEWG---------------QIFILDCLANY 229
Query: 260 GRNDDDSSEAMNDILAQVATNTETSKNVGNAILYETVLTIMDIKSE------SGLRVLAI 313
DD +++ I +V + + + ++ M++ S+ + L+ LA
Sbjct: 230 MPKDDREAQS---ICERVTPRLSHANSAVVLSAVKVLMKFMEMLSKDLDYYGTLLKKLAP 286
Query: 314 NILGRFLLNNDKNIRYVALTSLLKTVQTDHNAVQRHRSTIVDCLKDLDVSIKRRAMELSF 373
++ LL+ + ++YVAL ++ VQ + +H + + + +K +++
Sbjct: 287 PLV--TLLSAEPELQYVALRNINLIVQ-KRPEILKHEMKVFFVKYNDPIYVKLEKLDIMI 343
Query: 374 ALVNGNNIRGMMKELLYFLDSCEPEFKADCASGIFLAAEKYAPSKRWHIDTIMRVLTTAG 433
L + NI ++ EL + + +F I A K S + T++ ++ T
Sbjct: 344 RLASQANIAQVLAELKEYATEVDVDFVRKAVRAIGRCAIKVEQSAERCVSTLLDLIQTKV 403
Query: 434 SYVRDDAVPNLIQLITNSVEMHAYTVQRLYKAILGDYSQQPLVQVA-AWCIGEYGDLLVS 492
+YV +A+ + + + + L + + D +P + A W +GEY + +
Sbjct: 404 NYVVQEAIVVIKDIFRKYPNKYESVIATLCENL--DSLDEPEARAAMIWIVGEYAERI-- 459
Query: 493 GQCEEEEPIQVTEDEVLDILESVL--ISNMSTSVTRGYALTAIMKLSTRF-TCTVNRIKK 549
D ++LES L + ST V + LTAI+KL + T T +++
Sbjct: 460 -------------DNADELLESFLEGFHDESTQV-QLQLLTAIVKLFLKKPTETQELVQQ 505
Query: 550 VVSIYGSSID-VELQQRAVEYNALF-------------------KKYDHMRSALLERM-- 587
V+S+ D +L+ R Y L ++ D + LL+ +
Sbjct: 506 VLSLATQDSDNPDLRDRGYIYWRLLSTDPVAAKEVVLAEKPLISEETDLIEPTLLDELIC 565
Query: 588 --PVMEKVTTNGPTEIVQ--------------TNGETEPAPLETKP--PPSGPQP--TSQ 627
+ V P+ V+ + E+ +P ET P P G QP
Sbjct: 566 YIGTLASVYHKPPSAFVEGGRGVVHKSLPPRTASSESAESP-ETAPTGAPPGEQPDVIPA 624
Query: 628 ANDLLDLLGGNDITPVI---PTAPTSKPSSA----GGELLDLLGD--INLTGAPAAAPAP 678
DLL L D+ P + P A +S A GG L L+GD + G AP
Sbjct: 625 QGDLLGDLLNLDLGPPVSGPPLATSSVQMGAVDLLGGGLDSLMGDEPEGIGGTNFVAPPT 684
Query: 679 ASVPQISQPPFLLDGLSSQPLFNDIAAGIPSIT------------AYSKNGLKIEFTFER 726
A+VP P G LF D+ +G+ +++ A GL+I TF R
Sbjct: 685 AAVPANLGAPI---GSGLSDLF-DLTSGVGTLSGSYVAPKAVWLPAMKAKGLEISGTFTR 740
Query: 727 SNTNPSVTVITIQASNSTELDMTDFVFQ------AAVPKTFQLQL---LSPSSSIVPAFN 777
+ S + +Q +N MTDF Q P T LQ+ LSP+ ++ +
Sbjct: 741 QVGSIS---MDLQLTNKALQVMTDFAIQFNRNSFGLAPAT-PLQVHAPLSPNQTVEISLP 796
Query: 778 TGTITQVIKV--LNPQKQQLRMRIKLTY 803
T+ V+K+ LN + ++ I + Y
Sbjct: 797 LSTVGSVMKMEPLNNLQVAVKNNIDVFY 824
>gi|9558751 ADP-ribosylation factor binding protein 2 [Homo sapiens]
Length = 613
Score = 79.0 bits (193), Expect = 2e-14
Identities = 61/207 (29%), Positives = 99/207 (47%), Gaps = 38/207 (18%)
Query: 652 PSSA---GGELLDLLGDINLTGAPAAAPAPASVPQISQ-------PPF------------ 689
PSS+ GG + + D NL +A PAP + +SQ PP
Sbjct: 399 PSSSTLPGGGVQNPSADRNLLDLLSAQPAPCPLNYVSQKSVPKEVPPGTKSSPGWSWEAG 458
Query: 690 -LLDGLSSQ---------PLFNDIAAGIPSITAYSKNGLKIEFTFERSNT--NPSVTVIT 737
L SSQ PL + + +P + Y +NG +I F ++ +P V V+
Sbjct: 459 PLAPSPSSQNTPLAQVFVPLESVKPSSLPPLIVYDRNGFRILLHFSQTGAPGHPEVQVLL 518
Query: 738 IQASNSTELDMTDFVFQAAVPKTFQLQLLSPSSSIVPAFNT----GTITQVIKVLNPQKQ 793
+ ++ + D +FQ AVPK+ +++L SSS +PAF+ I+Q++ + NP K+
Sbjct: 519 LTMMSTAPQPVWDIMFQVAVPKSMRVKLQPASSSKLPAFSPLMPPAVISQMLLLDNPHKE 578
Query: 794 QLRMRIKLTYNHKGSAMQDLAEVNNFP 820
+R+R KLT+N G ++ EV +FP
Sbjct: 579 PIRLRYKLTFNQGGQPFSEVGEVKDFP 605
>gi|14719400 ADP-ribosylation factor binding protein 3 isoform short
[Homo sapiens]
Length = 690
Score = 77.8 bits (190), Expect = 4e-14
Identities = 59/195 (30%), Positives = 93/195 (47%), Gaps = 23/195 (11%)
Query: 641 TPVIPTAPTSKP----SSAGGELLDLLGDINLTGAPAAAPAPASVPQISQPPFLLDGLSS 696
+P+IPT ++P S+ G L G+P P S+ I P + S+
Sbjct: 505 SPLIPTTTPARPLLPFSTGPGSPLFQPLSFQSQGSPPKGPE-LSLASIHVPLESIKPSSA 563
Query: 697 QPLFNDIAAGIPSITAYSKNGLKIEFTFERSNT--NPSVTVITIQASNSTELDMTDFVFQ 754
P +TAY KNG +I F F + P V V+ + N+ L + V Q
Sbjct: 564 LP-----------VTAYDKNGFRILFHFAKECPPGRPDVLVVVVSMLNTAPLPVKSIVLQ 612
Query: 755 AAVPKTFQLQLLSPSSSIVPAFNT----GTITQVIKVLNPQKQQLRMRIKLTYNHKGSAM 810
AAVPK+ +++L PS + + F+ ITQV+ + NP K+++R+R KLT+
Sbjct: 613 AAVPKSMKVKLQPPSGTELSPFSPIQPPAAITQVMLLANPLKEKVRLRYKLTFALGEQLS 672
Query: 811 QDLAEVNNFPP-QSW 824
++ EV+ FPP + W
Sbjct: 673 TEVGEVDQFPPVEQW 687
>gi|20336267 ADP-ribosylation factor binding protein 3 isoform long
[Homo sapiens]
Length = 723
Score = 77.8 bits (190), Expect = 4e-14
Identities = 59/195 (30%), Positives = 93/195 (47%), Gaps = 23/195 (11%)
Query: 641 TPVIPTAPTSKP----SSAGGELLDLLGDINLTGAPAAAPAPASVPQISQPPFLLDGLSS 696
+P+IPT ++P S+ G L G+P P S+ I P + S+
Sbjct: 538 SPLIPTTTPARPLLPFSTGPGSPLFQPLSFQSQGSPPKGPE-LSLASIHVPLESIKPSSA 596
Query: 697 QPLFNDIAAGIPSITAYSKNGLKIEFTFERSNT--NPSVTVITIQASNSTELDMTDFVFQ 754
P +TAY KNG +I F F + P V V+ + N+ L + V Q
Sbjct: 597 LP-----------VTAYDKNGFRILFHFAKECPPGRPDVLVVVVSMLNTAPLPVKSIVLQ 645
Query: 755 AAVPKTFQLQLLSPSSSIVPAFNT----GTITQVIKVLNPQKQQLRMRIKLTYNHKGSAM 810
AAVPK+ +++L PS + + F+ ITQV+ + NP K+++R+R KLT+
Sbjct: 646 AAVPKSMKVKLQPPSGTELSPFSPIQPPAAITQVMLLANPLKEKVRLRYKLTFALGEQLS 705
Query: 811 QDLAEVNNFPP-QSW 824
++ EV+ FPP + W
Sbjct: 706 TEVGEVDQFPPVEQW 720
>gi|71773106 adaptor-related protein complex 2, beta 1 subunit
isoform a [Homo sapiens]
Length = 951
Score = 75.9 bits (185), Expect = 1e-13
Identities = 145/679 (21%), Positives = 272/679 (40%), Gaps = 79/679 (11%)
Query: 82 KRIGYLGAMLLLDERQDVHLLMTNCIKNDLNHSTQFVQGLALCTLGCMGSSEMCRDLAGE 141
K++ YL M + D+ ++ N D ++ LA+ T+GC+ ++ L
Sbjct: 66 KKLVYLYLMNYAKSQPDMAIMAVNSFVKDCEDPNPLIRALAVRTMGCIRVDKITEYLCEP 125
Query: 142 VEKLLKTSNSYLRKKAALCA--VHVIRKVPELMEMFLPATKNLLNEKNHGVLHTSVVLLT 199
+ K LK + Y+RK AA+C +H I + FL + ++L+ + N V+ +V L+
Sbjct: 126 LRKCLKDEDPYVRKTAAVCVAKLHDINAQMVEDQGFLDSLRDLIADSNPMVVANAVAALS 185
Query: 200 EMCERSPDMLAHFRKNEKLVPQLVRILKNLIMSGYSPEHDVSGISDPFLQVRILRLLRIL 259
E+ E P+ N + + +L+ L G Q+ IL L
Sbjct: 186 EISESHPNSNL-LDLNPQNINKLLTALNECTEWG---------------QIFILDCLSNY 229
Query: 260 GRNDDDSSEAMNDILAQVATNTETSKNVGNAILYETVLTIMD----IKSESGLRVLAINI 315
DD ++++ + + T + +A++ V +M + +S + +
Sbjct: 230 NPKDDREAQSICERV------TPRLSHANSAVVLSAVKVLMKFLELLPKDSDYYNMLLKK 283
Query: 316 LGR---FLLNNDKNIRYVALTSLLKTVQTDHNAVQRHRSTIVDCLKDLDVSIKRRAMELS 372
L LL+ + ++YVAL ++ VQ +++ D + +K +++
Sbjct: 284 LAPPLVTLLSGEPEVQYVALRNINLIVQKRPEILKQEIKVFFVKYND-PIYVKLEKLDIM 342
Query: 373 FALVNGNNIRGMMKELLYFLDSCEPEFKADCASGIFLAAEKYAPSKRWHIDTIMRVLTTA 432
L + NI ++ EL + + +F I A K S + T++ ++ T
Sbjct: 343 IRLASQANIAQVLAELKEYATEVDVDFVRKAVRAIGRCAIKVEQSAERCVSTLLDLIQTK 402
Query: 433 GSYVRDDAVPNLIQLITNSVEMHAYTVQRLYKAILGDYSQQPLVQVA-AWCIGEYGDLLV 491
+YV +A+ + + + + L + + D +P + A W +GEY + +
Sbjct: 403 VNYVVQEAIVVIRDIFRKYPNKYESIIATLCENL--DSLDEPDARAAMIWIVGEYAERI- 459
Query: 492 SGQCEEEEPIQVTEDEVLDILESVL--ISNMSTSVTRGYALTAIMKLSTRFTC-TVNRIK 548
D ++LES L + ST V + LTAI+KL + T ++
Sbjct: 460 --------------DNADELLESFLEGFHDESTQV-QLTLLTAIVKLFLKKPSETQELVQ 504
Query: 549 KVVSIYGSSID-VELQQRAVEYNALFK--KYDHMRSALLERMPVMEKVTTNGPT---EIV 602
+V+S+ D +L+ R Y L L E+ + E+ PT E++
Sbjct: 505 QVLSLATQDSDNPDLRDRGYIYWRLLSTDPVTAKEVVLSEKPLISEETDLIEPTLLDELI 564
Query: 603 QTNGETEPAPLETKPPPSGPQPTSQAN-DLLDLLGGNDITPVIPTAPTSKPSSAGGELL- 660
G A + KPP + + + + L + G+ P T+ + +++
Sbjct: 565 CHIGSL--ASVYHKPPNAFVEGSHGIHRKHLPIHHGSTDAGDSPVGTTTATNLEQPQVIP 622
Query: 661 ---DLLGD-INLTGAPAAAPAPASVPQISQPPF----LLDGLSSQPLFNDIAAGIPSITA 712
DLLGD +NL P P +VPQ+S LL G L +D+ GI A
Sbjct: 623 SQGDLLGDLLNLDLGP-----PVNVPQVSSMQMGAVDLLGGGLDSLLGSDLGGGIGGSPA 677
Query: 713 YSKNGL--KIEFTFERSNT 729
++ + + TF S T
Sbjct: 678 VGQSFIPSSVPATFAPSPT 696
>gi|239758145 PREDICTED: similar to ADP-ribosylation factor binding
protein 2 [Homo sapiens]
Length = 134
Score = 75.5 bits (184), Expect = 2e-13
Identities = 39/120 (32%), Positives = 69/120 (57%), Gaps = 6/120 (5%)
Query: 707 IPSITAYSKNGLKIEFTFERSNT--NPSVTVITIQASNSTELDMTDFVFQAAVPKTFQLQ 764
+P + Y +NG +I F ++ +P V V+ + ++ + D +FQ AVPK+ +++
Sbjct: 7 LPPLIVYDRNGFRILLHFSQTGAPGHPEVQVLLLTMMSTAPQPVWDIMFQVAVPKSMRVK 66
Query: 765 LLSPSSSIVPAFNT----GTITQVIKVLNPQKQQLRMRIKLTYNHKGSAMQDLAEVNNFP 820
L SSS +PAF+ I+Q++ + NP K+ +R+R KLT+N G ++ EV +FP
Sbjct: 67 LQPASSSKLPAFSPLMPPAVISQMLLLDNPHKEPIRLRYKLTFNQGGQPFSEVGEVKDFP 126
>gi|4557469 adaptor-related protein complex 2, beta 1 subunit
isoform b [Homo sapiens]
Length = 937
Score = 74.3 bits (181), Expect = 4e-13
Identities = 158/786 (20%), Positives = 295/786 (37%), Gaps = 100/786 (12%)
Query: 82 KRIGYLGAMLLLDERQDVHLLMTNCIKNDLNHSTQFVQGLALCTLGCMGSSEMCRDLAGE 141
K++ YL M + D+ ++ N D ++ LA+ T+GC+ ++ L
Sbjct: 66 KKLVYLYLMNYAKSQPDMAIMAVNSFVKDCEDPNPLIRALAVRTMGCIRVDKITEYLCEP 125
Query: 142 VEKLLKTSNSYLRKKAALCA--VHVIRKVPELMEMFLPATKNLLNEKNHGVLHTSVVLLT 199
+ K LK + Y+RK AA+C +H I + FL + ++L+ + N V+ +V L+
Sbjct: 126 LRKCLKDEDPYVRKTAAVCVAKLHDINAQMVEDQGFLDSLRDLIADSNPMVVANAVAALS 185
Query: 200 EMCERSPDMLAHFRKNEKLVPQLVRILKNLIMSGYSPEHDVSGISDPFLQVRILRLLRIL 259
E+ E P+ N + + +L+ L G Q+ IL L
Sbjct: 186 EISESHPNSNL-LDLNPQNINKLLTALNECTEWG---------------QIFILDCLSNY 229
Query: 260 GRNDDDSSEAMNDILAQVATNTETSKNVGNAILYETVLTIMD----IKSESGLRVLAINI 315
DD ++++ + + T + +A++ V +M + +S + +
Sbjct: 230 NPKDDREAQSICERV------TPRLSHANSAVVLSAVKVLMKFLELLPKDSDYYNMLLKK 283
Query: 316 LGR---FLLNNDKNIRYVALTSLLKTVQTDHNAVQRHRSTIVDCLKDLDVSIKRRAMELS 372
L LL+ + ++YVAL ++ VQ +++ D + +K +++
Sbjct: 284 LAPPLVTLLSGEPEVQYVALRNINLIVQKRPEILKQEIKVFFVKYND-PIYVKLEKLDIM 342
Query: 373 FALVNGNNIRGMMKELLYFLDSCEPEFKADCASGIFLAAEKYAPSKRWHIDTIMRVLTTA 432
L + NI ++ EL + + +F I A K S + T++ ++ T
Sbjct: 343 IRLASQANIAQVLAELKEYATEVDVDFVRKAVRAIGRCAIKVEQSAERCVSTLLDLIQTK 402
Query: 433 GSYVRDDAVPNLIQLITNSVEMHAYTVQRLYKAILGDYSQQPLVQVA-AWCIGEYGDLL- 490
+YV +A+ + + + + L + + D +P + A W +GEY + +
Sbjct: 403 VNYVVQEAIVVIRDIFRKYPNKYESIIATLCENL--DSLDEPDARAAMIWIVGEYAERID 460
Query: 491 ---------VSGQCEEEEPIQVT------------EDEVLDILESVLI-----SNMSTSV 524
+ G +E +Q+T E ++++ VL S+
Sbjct: 461 NADELLESFLEGFHDESTQVQLTLLTAIVKLFLKKPSETQELVQQVLSLATQDSDNPDLR 520
Query: 525 TRGYALTAIMKLS-TRFTCTVNRIKKVVSIYGSSIDVELQQRAV-EYNALFKKYDHMRSA 582
RGY ++ V K ++S I+ L + +L Y +A
Sbjct: 521 DRGYIYWRLLSTDPVTAKEVVLSEKPLISEETDLIEPTLLDELICHIGSLASVYHKPPNA 580
Query: 583 LLE--------RMPVMEKVTTNGPTEIVQTNGETEPAPLETKPPPSGPQPTSQANDLLDL 634
+E +P+ T G + + G T LE P P DLL+L
Sbjct: 581 FVEGSHGIHRKHLPIHHGSTDAGDSPV----GTTTATNLE--QPQVIPSQGDLLGDLLNL 634
Query: 635 -LGGNDITPVIPTAPTSKPSSAGGELLDLLGDINLTGAPAAAPAPASVPQISQPPF---- 689
LG P + + GG L L+G + + A AP+ P +
Sbjct: 635 DLGPPVNVPQVSSMQMGAVDLLGGGLDSLVGQSFIPSSVPATFAPSPTPAVVSSGLNDLF 694
Query: 690 -LLDGLSSQPLFNDIAAGIPSITAYSKNGLKIEFTFERSNTNPSVTVITIQASNSTELDM 748
L G+ P +A + A GL+I TF + + + +N M
Sbjct: 695 ELSTGIGMAP-GGYVAPKAVWLPAVKAKGLEISGTFTHRQGH---IYMEMNFTNKALQHM 750
Query: 749 TDFVFQ------AAVPKTFQLQL---LSPSSSIVPAFNTGTITQVIKV--LNPQKQQLRM 797
TDF Q +P T L + L P+ SI + T+ V+K+ LN + ++
Sbjct: 751 TDFAIQFNKNSFGVIPST-PLAIHTPLMPNQSIDVSLPLNTLGPVMKMEPLNNLQVAVKN 809
Query: 798 RIKLTY 803
I + Y
Sbjct: 810 NIDVFY 815
>gi|109134349 coatomer protein complex, subunit gamma 2 [Homo
sapiens]
Length = 871
Score = 61.2 bits (147), Expect = 4e-09
Identities = 81/407 (19%), Positives = 164/407 (40%), Gaps = 48/407 (11%)
Query: 43 NTYRCRNV-AKLLYMHMLGYPAHFGQLECL-------KLIASQKFTDKRIGYLGAMLLLD 94
N RC ++ K+LY+ L HFG E +L S T +R+ YL +
Sbjct: 40 NPRRCLHILTKILYL--LNQGEHFGTTEATEAFFAMTRLFQSNDQTLRRMCYLTIKEMAT 97
Query: 95 ERQDVHLLMTNCIKNDLNHSTQFVQGLALCTLGCMGSSEMCRDLAGEVEKLLKTSNSYLR 154
+DV +++T+ + D+ +G A+ L + M + + +++ + S +
Sbjct: 98 ISEDV-IIVTSSLTKDMTGKEDVYRGPAIRALCRITDGTMLQAIERYMKQAIVDKVSSVS 156
Query: 155 KKAALCAVHVIRKVPELMEMFLPATKNLLNEKNHGVLHTSVVLLTEMCERSPDMLAHFRK 214
A + ++H +M++ K +NE ++++ +L H RK
Sbjct: 157 SSALVSSLH-------MMKISYDVVKRWINEAQEAASSDNIMVQYHAL----GVLYHLRK 205
Query: 215 NEKLVPQLVRILKNLIMSGYSPEHDVSGISDPFLQVRILRLL-RILGRNDDDSSEAMNDI 273
N++L +S + SG+ F ++R+ R+L +D + D
Sbjct: 206 NDRLA-----------VSKMLNKFTKSGLKSQFAYCMLIRIASRLLKETEDGHESPLFDF 254
Query: 274 LAQVATNTETSKNVGNAILYETVLTIMDIKSESGLRVL-AINILGRFLLNNDKNIRYVAL 332
+ N ++YE I+ + + + + A+++L F + +RY A+
Sbjct: 255 IESCLRNKH------EMVIYEAASAIIHLPNCTARELAPAVSVLQLFCSSPKPALRYAAV 308
Query: 333 TSLLKTVQTDHNAVQRHRSTIVDCLKDLDVSIKRRAMELSFALVNGNNIRGMMKELLYFL 392
+L K +AV + + + D + SI A+ + +++ +MK++ F+
Sbjct: 309 RTLNKVAMKHPSAVTACNLDLENLITDSNRSIATLAITTLLKTGSESSVDRLMKQISSFV 368
Query: 393 DSCEPEFKADCASGIFLAAEKYAPSKRWHIDTIMRVLTTAGSYVRDD 439
EFK I +KY P K ++M +T + +RDD
Sbjct: 369 SEISDEFKVVVVQAISALCQKY-PRKH----SVM--MTFLSNMLRDD 408
>gi|221316632 coatomer protein complex, subunit beta 1 [Homo
sapiens]
Length = 953
Score = 55.1 bits (131), Expect = 3e-07
Identities = 87/477 (18%), Positives = 191/477 (40%), Gaps = 76/477 (15%)
Query: 101 LLMTNCIKNDLNHSTQFVQGLALCTLGCMGSSEMCRDLAGEVEKLLKTSNSYLRKKAALC 160
+L+ + + DL H +F++G L L + +E+ L + L+ +SY+R+ A L
Sbjct: 99 ILVCDAYRKDLQHPNEFIRGSTLRFLCKLKEAELLEPLMPAIRACLEHRHSYVRRNAVLA 158
Query: 161 AV-------HVIRKVPELMEMFLPATKNLLNEKNHGVLHTSVVLLTEMCERSPDMLAHFR 213
H+I PEL+ F L+NEK+ C+R+ M+
Sbjct: 159 IYTIYRNFEHLIPDAPELIHDF------LVNEKD------------ASCKRNAFMMLIHA 200
Query: 214 KNEKLVPQLVRILKNLIMSGYSPEHDVSGISDPFLQVRILRLL-RILGRNDDDSSEAMND 272
++ + L + + G LQ+ I+ L+ ++ N + + +
Sbjct: 201 DQDRALDYLSTCIDQVQTFG------------DILQLVIVELIYKVCHANPSERARFIRC 248
Query: 273 ILAQVATNTETSKNVGNAILYETVLTIMDIKS-ESGLRVLAINILGRFLLNNDKNIRYVA 331
I + +++ A+ YE T++ + S + ++ A + + +D N++ +
Sbjct: 249 IYNLLQSSSP-------AVKYEAAGTLVTLSSAPTAIKAAAQCYIDLIIKESDNNVKLIV 301
Query: 332 LTSLLKTVQTDHNAVQR-HRSTIVDCLKDL---DVSIKRRAMELSFALVNGNNIRGMM-- 385
L L++ +H A +R + ++D L+ L D+ ++++ ++L+ LV+ N+ ++
Sbjct: 302 LDRLIEL--KEHPAHERVLQDLVMDILRVLSTPDLEVRKKTLQLALDLVSSRNVEELVIV 359
Query: 386 --KELLYFLDSCEPE----FKADCASGIFLAAEKYAPSKRWHIDTIMRVLTTAGSYVRDD 439
KE++ + E E ++ + + ++ I +M L+ D
Sbjct: 360 LKKEVIKTNNVSEHEDTDKYRQLLVRTLHSCSVRFPDMAANVIPVLMEFLSDNNEAAAAD 419
Query: 440 AVPNLIQLITNSVEMHAYTVQRLYKAILGDYSQQPLVQVAAWCIGEYGDLLVSGQCEEEE 499
+ + + I + V+++ + + + + A W +GEY C +E
Sbjct: 420 VLEFVREAIQRFDNLRMLIVEKMLE-VFHAIKSVKIYRGALWILGEY--------CSTKE 470
Query: 500 PIQVTEDEVLDILESVLISNMSTSVTRGYALTAIMKLSTRFTCTVNRIKKVVSIYGS 556
IQ E+ L + I G +L TV ++K+V+ G+
Sbjct: 471 DIQSVMTEIRRSLGEIPIVESEIKKEAG-------ELKPEEEITVGPVQKLVTEMGT 520
>gi|221316630 coatomer protein complex, subunit beta 1 [Homo
sapiens]
Length = 953
Score = 55.1 bits (131), Expect = 3e-07
Identities = 87/477 (18%), Positives = 191/477 (40%), Gaps = 76/477 (15%)
Query: 101 LLMTNCIKNDLNHSTQFVQGLALCTLGCMGSSEMCRDLAGEVEKLLKTSNSYLRKKAALC 160
+L+ + + DL H +F++G L L + +E+ L + L+ +SY+R+ A L
Sbjct: 99 ILVCDAYRKDLQHPNEFIRGSTLRFLCKLKEAELLEPLMPAIRACLEHRHSYVRRNAVLA 158
Query: 161 AV-------HVIRKVPELMEMFLPATKNLLNEKNHGVLHTSVVLLTEMCERSPDMLAHFR 213
H+I PEL+ F L+NEK+ C+R+ M+
Sbjct: 159 IYTIYRNFEHLIPDAPELIHDF------LVNEKD------------ASCKRNAFMMLIHA 200
Query: 214 KNEKLVPQLVRILKNLIMSGYSPEHDVSGISDPFLQVRILRLL-RILGRNDDDSSEAMND 272
++ + L + + G LQ+ I+ L+ ++ N + + +
Sbjct: 201 DQDRALDYLSTCIDQVQTFG------------DILQLVIVELIYKVCHANPSERARFIRC 248
Query: 273 ILAQVATNTETSKNVGNAILYETVLTIMDIKS-ESGLRVLAINILGRFLLNNDKNIRYVA 331
I + +++ A+ YE T++ + S + ++ A + + +D N++ +
Sbjct: 249 IYNLLQSSSP-------AVKYEAAGTLVTLSSAPTAIKAAAQCYIDLIIKESDNNVKLIV 301
Query: 332 LTSLLKTVQTDHNAVQR-HRSTIVDCLKDL---DVSIKRRAMELSFALVNGNNIRGMM-- 385
L L++ +H A +R + ++D L+ L D+ ++++ ++L+ LV+ N+ ++
Sbjct: 302 LDRLIEL--KEHPAHERVLQDLVMDILRVLSTPDLEVRKKTLQLALDLVSSRNVEELVIV 359
Query: 386 --KELLYFLDSCEPE----FKADCASGIFLAAEKYAPSKRWHIDTIMRVLTTAGSYVRDD 439
KE++ + E E ++ + + ++ I +M L+ D
Sbjct: 360 LKKEVIKTNNVSEHEDTDKYRQLLVRTLHSCSVRFPDMAANVIPVLMEFLSDNNEAAAAD 419
Query: 440 AVPNLIQLITNSVEMHAYTVQRLYKAILGDYSQQPLVQVAAWCIGEYGDLLVSGQCEEEE 499
+ + + I + V+++ + + + + A W +GEY C +E
Sbjct: 420 VLEFVREAIQRFDNLRMLIVEKMLE-VFHAIKSVKIYRGALWILGEY--------CSTKE 470
Query: 500 PIQVTEDEVLDILESVLISNMSTSVTRGYALTAIMKLSTRFTCTVNRIKKVVSIYGS 556
IQ E+ L + I G +L TV ++K+V+ G+
Sbjct: 471 DIQSVMTEIRRSLGEIPIVESEIKKEAG-------ELKPEEEITVGPVQKLVTEMGT 520
>gi|7705369 coatomer protein complex, subunit beta 1 [Homo sapiens]
Length = 953
Score = 55.1 bits (131), Expect = 3e-07
Identities = 87/477 (18%), Positives = 191/477 (40%), Gaps = 76/477 (15%)
Query: 101 LLMTNCIKNDLNHSTQFVQGLALCTLGCMGSSEMCRDLAGEVEKLLKTSNSYLRKKAALC 160
+L+ + + DL H +F++G L L + +E+ L + L+ +SY+R+ A L
Sbjct: 99 ILVCDAYRKDLQHPNEFIRGSTLRFLCKLKEAELLEPLMPAIRACLEHRHSYVRRNAVLA 158
Query: 161 AV-------HVIRKVPELMEMFLPATKNLLNEKNHGVLHTSVVLLTEMCERSPDMLAHFR 213
H+I PEL+ F L+NEK+ C+R+ M+
Sbjct: 159 IYTIYRNFEHLIPDAPELIHDF------LVNEKD------------ASCKRNAFMMLIHA 200
Query: 214 KNEKLVPQLVRILKNLIMSGYSPEHDVSGISDPFLQVRILRLL-RILGRNDDDSSEAMND 272
++ + L + + G LQ+ I+ L+ ++ N + + +
Sbjct: 201 DQDRALDYLSTCIDQVQTFG------------DILQLVIVELIYKVCHANPSERARFIRC 248
Query: 273 ILAQVATNTETSKNVGNAILYETVLTIMDIKS-ESGLRVLAINILGRFLLNNDKNIRYVA 331
I + +++ A+ YE T++ + S + ++ A + + +D N++ +
Sbjct: 249 IYNLLQSSSP-------AVKYEAAGTLVTLSSAPTAIKAAAQCYIDLIIKESDNNVKLIV 301
Query: 332 LTSLLKTVQTDHNAVQR-HRSTIVDCLKDL---DVSIKRRAMELSFALVNGNNIRGMM-- 385
L L++ +H A +R + ++D L+ L D+ ++++ ++L+ LV+ N+ ++
Sbjct: 302 LDRLIEL--KEHPAHERVLQDLVMDILRVLSTPDLEVRKKTLQLALDLVSSRNVEELVIV 359
Query: 386 --KELLYFLDSCEPE----FKADCASGIFLAAEKYAPSKRWHIDTIMRVLTTAGSYVRDD 439
KE++ + E E ++ + + ++ I +M L+ D
Sbjct: 360 LKKEVIKTNNVSEHEDTDKYRQLLVRTLHSCSVRFPDMAANVIPVLMEFLSDNNEAAAAD 419
Query: 440 AVPNLIQLITNSVEMHAYTVQRLYKAILGDYSQQPLVQVAAWCIGEYGDLLVSGQCEEEE 499
+ + + I + V+++ + + + + A W +GEY C +E
Sbjct: 420 VLEFVREAIQRFDNLRMLIVEKMLE-VFHAIKSVKIYRGALWILGEY--------CSTKE 470
Query: 500 PIQVTEDEVLDILESVLISNMSTSVTRGYALTAIMKLSTRFTCTVNRIKKVVSIYGS 556
IQ E+ L + I G +L TV ++K+V+ G+
Sbjct: 471 DIQSVMTEIRRSLGEIPIVESEIKKEAG-------ELKPEEEITVGPVQKLVTEMGT 520
>gi|32484979 adaptor-related protein complex 3, beta 1 subunit [Homo
sapiens]
Length = 1094
Score = 53.5 bits (127), Expect = 8e-07
Identities = 90/454 (19%), Positives = 183/454 (40%), Gaps = 71/454 (15%)
Query: 71 LKLIASQKFTDKRIGYLGAMLLLDERQDVHLLMTNCIKNDLNHSTQFVQGLALCTLGCMG 130
+K +AS+ K++ Y+ + +E+QD+ LL + + L Q ++ AL L +
Sbjct: 84 VKNVASKNIEIKKLVYVYLVRYAEEQQDLALLSISTFQRALKDPNQLIRASALRVLSSIR 143
Query: 131 SSEMCRDLAGEVEKLLKTSNSYLRKKAALCAVHVIRKV----PELMEMFLPATKNLLNEK 186
+ + +++ + Y+RK AA H I+K+ PE EM + + LL +K
Sbjct: 144 VPIIVPIMMLAIKEASADLSPYVRKNAA----HAIQKLYSLDPEQKEMLIEVIEKLLKDK 199
Query: 187 NHGVLHTSVVLLTEMCERSPDMLAHFRKNEK----------------LVPQLVRILKNLI 230
+ V + V+ E+C PD + KN + ++ L R +
Sbjct: 200 STLVAGSVVMAFEEVC---PDRIDLIHKNYRKLCNLLVDVEEWGQVVIIHMLTRYARTQF 256
Query: 231 MSGYSPEHDVSGISDPFLQVRILRLLRILGRNDDDSSE---------AMNDILAQVATNT 281
+S + ++ F + +DDD E M+ + NT
Sbjct: 257 VSPWKEGDELEDNGKNFYE------------SDDDQKEKTDKKKKPYTMDPDHRLLIRNT 304
Query: 282 ETSKNVGNAILYETVLTI---MDIKSESGLRVLAINILGRFLLNNDKNIRYVALTSLLKT 338
+ NA + V + + KSE+G +++ +++ LL +++ ++Y+ L ++
Sbjct: 305 KPLLQSRNAAVVMAVAQLYWHISPKSEAG--IISKSLVR--LLRSNREVQYIVLQNIATM 360
Query: 339 VQTDHNAVQRHRSTIVDCLKDLDV------SIKRRAMELSFALVNGNNIRGMMKELLYFL 392
++QR + LK V IK +E+ L N NI +++E ++
Sbjct: 361 ------SIQR-KGMFEPYLKSFYVRSTDPTMIKTLKLEILTNLANEANISTLLREFQTYV 413
Query: 393 DSCEPEFKADCASGIFLAAEKYAPSKRWHIDTIMRVLTTAGSYVRDDAVPNLIQLITNSV 452
S + +F A I A ++ ++ +L+ V ++V + +L+
Sbjct: 414 KSQDKQFAAATIQTIGRCATNILEVTDTCLNGLVCLLSNRDEIVVAESVVVIKKLLQMQP 473
Query: 453 EMHAYTVQRLYKAILGDYSQQPLVQVA-AWCIGE 485
H ++ + K + D P+ + + W IGE
Sbjct: 474 AQHGEIIKHMAKLL--DSITVPVARASILWLIGE 505
>gi|11559929 coatomer protein complex, subunit gamma 1 [Homo
sapiens]
Length = 874
Score = 52.4 bits (124), Expect = 2e-06
Identities = 78/413 (18%), Positives = 166/413 (40%), Gaps = 41/413 (9%)
Query: 43 NTYRCRNV-AKLLYMHMLGYPAHFGQLECL-------KLIASQKFTDKRIGYLGAMLLLD 94
N +C ++ K+LY+ G H G E KL S T +R+ YL +
Sbjct: 40 NPRKCAHILTKILYLINQG--EHLGTTEATEAFFAMTKLFQSNDPTLRRMCYLTIKEMSC 97
Query: 95 ERQDVHLLMTNCIKNDLNHSTQFVQGLALCTLGCMGSSEMCRDLAGEVEKLLKTSNSYLR 154
+DV +++T+ + D+ +G A+ L + S M + + +++ + +
Sbjct: 98 IAEDV-IIVTSSLTKDMTGKEDNYRGPAVRALCQITDSTMLQAIERYMKQAIVDKVPSVS 156
Query: 155 KKAALCAVHVIRKVPELMEMFLPATKNLLNEKNHGVLHTSVVLLTEMCERSPDMLAHFRK 214
A + ++H+++ ++++ ++ + + N V + ++ LL H RK
Sbjct: 157 SSALVSSLHLLKCSFDVVKRWVNEAQEAASSDNIMVQYHALGLLY-----------HVRK 205
Query: 215 NEKLVPQLVRILKNLIMSGYSPEHDVSGISDPFLQVRILRLL-RILGRNDDDSSEAMNDI 273
N++L N ++S + G+ PF ++R+ + L D + D
Sbjct: 206 NDRLAV-------NKMISKVTRH----GLKSPFAYCMMIRVASKQLEEEDGSRDSPLFDF 254
Query: 274 LAQVATNTETSKNVGNAILYETVLTIMDIKSESGLRVL-AINILGRFLLNNDKNIRYVAL 332
+ N ++YE I+++ S + A+++L F + +RY A+
Sbjct: 255 IESCLRNKH------EMVVYEAASAIVNLPGCSAKELAPAVSVLQLFCSSPKAALRYAAV 308
Query: 333 TSLLKTVQTDHNAVQRHRSTIVDCLKDLDVSIKRRAMELSFALVNGNNIRGMMKELLYFL 392
+L K +AV + + + D + SI A+ + ++I +MK++ F+
Sbjct: 309 RTLNKVAMKHPSAVTACNLDLENLVTDSNRSIATLAITTLLKTGSESSIDRLMKQISSFM 368
Query: 393 DSCEPEFKADCASGIFLAAEKYAPSKRWHIDTIMRVLTTAGSYVRDDAVPNLI 445
EFK I +KY ++ + +L G + A+ + I
Sbjct: 369 SEISDEFKVVVVQAISALCQKYPRKHAVLMNFLFTMLREEGGFEYKRAIVDCI 421
>gi|166197671 adaptor-related protein complex 4, beta 1 subunit
[Homo sapiens]
Length = 739
Score = 41.6 bits (96), Expect = 0.003
Identities = 93/483 (19%), Positives = 194/483 (40%), Gaps = 42/483 (8%)
Query: 46 RCRNVAKLLYMHML-GYPAHFGQLECLKLIASQKFTDKRIGYLGAMLLLDERQDVHLLMT 104
R RNV + + +M G +E +K A+ K++ YL + D+ LL
Sbjct: 28 RYRNVIQRVIRYMTQGLDMSGVFMEMVKASATVDIVQKKLVYLYMCTYAPLKPDLALLAI 87
Query: 105 NCIKNDLNHSTQFVQGLAL---CTLGCMGSSEMCRDLAGEVEKLLKTSNSYLRKKAAL-C 160
N + D + V+GLAL C+L G E + + L+ SY+R+ A L C
Sbjct: 88 NTLCKDCSDPNPMVRGLALRSMCSLRMPGVQEYIQQ---PILNGLRDKASYVRRVAVLGC 144
Query: 161 A-VHVIRKVPELMEMFLPATKNLLNEKNHGVLHTSVVLLTEMCERSPDMLAHFRKNEKLV 219
A +H + E+ + +LL +++ V+ + L E+ ++ ++ N+ +
Sbjct: 145 AKMHNLHGDSEVDGALVNELYSLLRDQDPIVVVNCLRSLEEILKQEGGVVI----NKPIA 200
Query: 220 PQLVRILKNLIMSGYSPEHDVSGISDPFLQVRILR-LLRILGRNDDDSSEAMNDILAQVA 278
L+ + L D + Q +L LLR R++++ + +N +L
Sbjct: 201 HHLLNRMSKL---------------DQWGQAEVLNFLLRYQPRSEEELFDILN-LLDSFL 244
Query: 279 TNTETSKNVGNAILYETVLTIMDIKSESGLRVLAINILGRFLLNNDKNIRYVALTSLLKT 338
++ +G L+ +L M ++ + V L + + + +VAL + +
Sbjct: 245 KSSSPGVVMGATKLF-LILAKMFPHVQTDVLVRVKGPLLAACSSESRELCFVALCHVRQI 303
Query: 339 VQTDHNAVQRHRSTIVDCLKDLDVSIKRRAMELSFALVNGNNIRGMMKELLYFLDSCEPE 398
+ + H C IK + +E+ LVN N++ +++EL + +
Sbjct: 304 LHSLPGHFSSHYKKFF-CSYSEPHYIKLQKVEVLCELVNDENVQQVLEELRGYC----TD 358
Query: 399 FKADCASGIFLAAEKYAPSKRWHIDTIMRVLTTAGSYVRDDAVPNLIQLITNSVEMHAYT 458
AD A A A R + D +++LT ++ ++Q + V +
Sbjct: 359 VSADFAQAAIFAIGGIA---RTYTDQCVQILTELLGLRQEHITTVVVQTFRDLVWLCPQC 415
Query: 459 VQRLYKAILG---DYSQQPLVQVAAWCIGEYGDLLVSGQCEEEEPIQVTEDEVLDILESV 515
+ + +A+ G + Q W +G +G+ + + E+ ++ + E ++
Sbjct: 416 TEAVCQALPGCEENIQDSEGKQALIWLLGVHGERIPNAPYVLEDFVENVKSETFPAVKME 475
Query: 516 LIS 518
L++
Sbjct: 476 LLT 478
>gi|31324577 molecule interacting with Rab13 [Homo sapiens]
Length = 863
Score = 39.7 bits (91), Expect = 0.012
Identities = 39/166 (23%), Positives = 74/166 (44%), Gaps = 9/166 (5%)
Query: 601 IVQTNGETEPAPLETKPPPSGPQPTSQANDLLDLLGGNDITPVIPTAPTSKPSSAGGELL 660
+VQ + +PAPL PP S P P SQ + ++ G ++ PTA E
Sbjct: 374 LVQAEPKKKPAPL---PPSSSPGPPSQDSRQVENGGTEEVAQPSPTASLESKPYNPFEEE 430
Query: 661 DLLGDINLTGAPAAAPAPA-----SVPQISQPPFLLDGLSSQPLFNDIAAGIPSITAYSK 715
+ + AP+ A +PA S P+ P + + SS A PS + +
Sbjct: 431 EEDKEEEAPAAPSLATSPALGHPESTPKSLHPWYGITPTSSPKTKKRPAPRAPSASPLAL 490
Query: 716 NGLKIEFTFERSNT-NPSVTVITIQASNSTELDMTDFVFQAAVPKT 760
+ ++ + S T +P+++V ++ + ++++ + + AVPK+
Sbjct: 491 HASRLSHSEPPSATPSPALSVESLSSESASQTAGAELLEPPAVPKS 536
>gi|241982780 programmed cell death 6 interacting protein isoform 2
[Homo sapiens]
Length = 873
Score = 37.7 bits (86), Expect = 0.044
Identities = 41/182 (22%), Positives = 69/182 (37%), Gaps = 38/182 (20%)
Query: 512 LESVLISNMSTSVTRGYALTAIMKLSTRFTCTVNRIKKVVSIYGSSIDVELQQRAVEYNA 571
L ++ N++T+ L A +K T+F N + +++ + + + R E +
Sbjct: 653 LREEVLKNLATAYDNFVELVANLKEGTKF---YNELTEILVRFQNKCSDIVFARKTERDE 709
Query: 572 LFKKYDHMRSALLERMPVMEKVTTNGPTEIVQTN-----GETEPAPLETKPPPSGPQPTS 626
L K L++ E + PT Q++ T P P PP+ PQP +
Sbjct: 710 LLKD--------LQQSIAREPSAPSIPTPAYQSSPAGGHAPTPPTPAPRTMPPTKPQPPA 761
Query: 627 QANDLLDLLGGNDITPVIPTAPTSKPSSAGGELLDLLGDINLTGAPAAAPAPASVPQISQ 686
+ P P P ++ SA + GA AAPAP+ P +
Sbjct: 762 R--------------PPPPVLPANRAPSATAP--------SPVGAGTAAPAPSQTPGSAP 799
Query: 687 PP 688
PP
Sbjct: 800 PP 801
>gi|22027538 programmed cell death 6 interacting protein isoform 1
[Homo sapiens]
Length = 868
Score = 37.7 bits (86), Expect = 0.044
Identities = 41/182 (22%), Positives = 69/182 (37%), Gaps = 38/182 (20%)
Query: 512 LESVLISNMSTSVTRGYALTAIMKLSTRFTCTVNRIKKVVSIYGSSIDVELQQRAVEYNA 571
L ++ N++T+ L A +K T+F N + +++ + + + R E +
Sbjct: 648 LREEVLKNLATAYDNFVELVANLKEGTKF---YNELTEILVRFQNKCSDIVFARKTERDE 704
Query: 572 LFKKYDHMRSALLERMPVMEKVTTNGPTEIVQTN-----GETEPAPLETKPPPSGPQPTS 626
L K L++ E + PT Q++ T P P PP+ PQP +
Sbjct: 705 LLKD--------LQQSIAREPSAPSIPTPAYQSSPAGGHAPTPPTPAPRTMPPTKPQPPA 756
Query: 627 QANDLLDLLGGNDITPVIPTAPTSKPSSAGGELLDLLGDINLTGAPAAAPAPASVPQISQ 686
+ P P P ++ SA + GA AAPAP+ P +
Sbjct: 757 R--------------PPPPVLPANRAPSATAP--------SPVGAGTAAPAPSQTPGSAP 794
Query: 687 PP 688
PP
Sbjct: 795 PP 796
>gi|153792780 additional sex combs like 2 [Homo sapiens]
Length = 1435
Score = 37.7 bits (86), Expect = 0.044
Identities = 64/232 (27%), Positives = 88/232 (37%), Gaps = 26/232 (11%)
Query: 588 PVMEKVTTN---GPTEIVQTNGETEPAPLETKPPPSGPQPTSQANDLLDLLGGNDITPVI 644
P +E T G E++ ET+P ETK PS QP S + L TP +
Sbjct: 727 PTLELAGTGSRGGTRELLPCGPETQPQS-ETKTTPSQAQPHSVSGAQLQQTPPVPPTPAV 785
Query: 645 PTAPTSKPSSAGGELLDLLGDINLTGAPAAAPA------PASVPQISQP----PFLLDGL 694
A TS PS A E LD +N T A A + P+S Q P P L+ G
Sbjct: 786 SGACTSVPSPAHIEKLD-NEKLNPTRATATVASVSHPQGPSSCRQEKAPSPTGPALISGA 844
Query: 695 SSQPLFND----IAAG----IPSITAYSKNGLKIEFTFERSNTNPSVTVITIQASNSTEL 746
S D + AG IP+ +A SK + S +T T++ ++
Sbjct: 845 SPVHCAADGTVELKAGPSKNIPNPSASSKTDASVPVAVTPSPLTSLLTTATLEKLPVPQV 904
Query: 747 DMTDFVFQAAVPKT---FQLQLLSPSSSIVPAFNTGTITQVIKVLNPQKQQL 795
T +A P + L +P +S+ T T I NP QL
Sbjct: 905 SATTAPAGSAPPSSTLPAASSLKTPGTSLNMNGPTLRPTSSIPANNPLVTQL 956
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.318 0.133 0.378
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 29,517,038
Number of Sequences: 37866
Number of extensions: 1382047
Number of successful extensions: 6276
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 30
Number of HSP's successfully gapped in prelim test: 128
Number of HSP's that attempted gapping in prelim test: 5907
Number of HSP's gapped (non-prelim): 418
length of query: 825
length of database: 18,247,518
effective HSP length: 111
effective length of query: 714
effective length of database: 14,044,392
effective search space: 10027695888
effective search space used: 10027695888
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.