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Search of human proteins with 71772942
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|71772942 adaptor-related protein complex 1, gamma 1 subunit
isoform b [Homo sapiens]
(822 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|71772942 adaptor-related protein complex 1, gamma 1 subunit i... 1613 0.0
gi|71773010 adaptor-related protein complex 1, gamma 1 subunit i... 1608 0.0
gi|4503843 adaptor-related protein complex 1, gamma 2 subunit [H... 941 0.0
gi|19913414 adaptor-related protein complex 2, alpha 1 subunit i... 278 1e-74
gi|19913416 adaptor-related protein complex 2, alpha 1 subunit i... 278 1e-74
gi|27477041 adaptor-related protein complex 2, alpha 2 subunit [... 277 3e-74
gi|37675283 adaptor-related protein complex 4, epsilon 1 subunit... 238 2e-62
gi|117553580 adaptor-related protein complex 3, delta 1 subunit ... 170 4e-42
gi|117553584 adaptor-related protein complex 3, delta 1 subunit ... 96 2e-19
gi|22027653 adaptor-related protein complex 1 beta 1 subunit iso... 94 7e-19
gi|22027651 adaptor-related protein complex 1 beta 1 subunit iso... 92 1e-18
gi|9558729 golgi associated, gamma adaptin ear containing, ARF b... 92 2e-18
gi|48527952 golgi associated, gamma adaptin ear containing, ARF ... 92 2e-18
gi|9558751 ADP-ribosylation factor binding protein 2 [Homo sapiens] 79 2e-14
gi|71773106 adaptor-related protein complex 2, beta 1 subunit is... 78 4e-14
gi|14719400 ADP-ribosylation factor binding protein 3 isoform sh... 78 4e-14
gi|20336267 ADP-ribosylation factor binding protein 3 isoform lo... 78 4e-14
gi|4557469 adaptor-related protein complex 2, beta 1 subunit iso... 76 1e-13
gi|239758145 PREDICTED: similar to ADP-ribosylation factor bindi... 75 2e-13
gi|109134349 coatomer protein complex, subunit gamma 2 [Homo sap... 57 9e-08
gi|32484979 adaptor-related protein complex 3, beta 1 subunit [H... 54 6e-07
gi|221316632 coatomer protein complex, subunit beta 1 [Homo sapi... 54 6e-07
gi|221316630 coatomer protein complex, subunit beta 1 [Homo sapi... 54 6e-07
gi|7705369 coatomer protein complex, subunit beta 1 [Homo sapiens] 54 6e-07
gi|11559929 coatomer protein complex, subunit gamma 1 [Homo sapi... 52 2e-06
gi|166197671 adaptor-related protein complex 4, beta 1 subunit [... 41 0.004
gi|31324577 molecule interacting with Rab13 [Homo sapiens] 40 0.011
gi|241982780 programmed cell death 6 interacting protein isoform... 38 0.044
gi|22027538 programmed cell death 6 interacting protein isoform ... 38 0.044
gi|153792780 additional sex combs like 2 [Homo sapiens] 38 0.044
>gi|71772942 adaptor-related protein complex 1, gamma 1 subunit
isoform b [Homo sapiens]
Length = 822
Score = 1613 bits (4178), Expect = 0.0
Identities = 822/822 (100%), Positives = 822/822 (100%)
Query: 1 MPAPIRLRELIRTIRTARTQAEEREMIQKECAAIRSSFREEDNTYRCRNVAKLLYMHMLG 60
MPAPIRLRELIRTIRTARTQAEEREMIQKECAAIRSSFREEDNTYRCRNVAKLLYMHMLG
Sbjct: 1 MPAPIRLRELIRTIRTARTQAEEREMIQKECAAIRSSFREEDNTYRCRNVAKLLYMHMLG 60
Query: 61 YPAHFGQLECLKLIASQKFTDKRIGYLGAMLLLDERQDVHLLMTNCIKNDLNHSTQFVQG 120
YPAHFGQLECLKLIASQKFTDKRIGYLGAMLLLDERQDVHLLMTNCIKNDLNHSTQFVQG
Sbjct: 61 YPAHFGQLECLKLIASQKFTDKRIGYLGAMLLLDERQDVHLLMTNCIKNDLNHSTQFVQG 120
Query: 121 LALCTLGCMGSSEMCRDLAGEVEKLLKTSNSYLRKKAALCAVHVIRKVPELMEMFLPATK 180
LALCTLGCMGSSEMCRDLAGEVEKLLKTSNSYLRKKAALCAVHVIRKVPELMEMFLPATK
Sbjct: 121 LALCTLGCMGSSEMCRDLAGEVEKLLKTSNSYLRKKAALCAVHVIRKVPELMEMFLPATK 180
Query: 181 NLLNEKNHGVLHTSVVLLTEMCERSPDMLAHFRKLVPQLVRILKNLIMSGYSPEHDVSGI 240
NLLNEKNHGVLHTSVVLLTEMCERSPDMLAHFRKLVPQLVRILKNLIMSGYSPEHDVSGI
Sbjct: 181 NLLNEKNHGVLHTSVVLLTEMCERSPDMLAHFRKLVPQLVRILKNLIMSGYSPEHDVSGI 240
Query: 241 SDPFLQVRILRLLRILGRNDDDSSEAMNDILAQVATNTETSKNVGNAILYETVLTIMDIK 300
SDPFLQVRILRLLRILGRNDDDSSEAMNDILAQVATNTETSKNVGNAILYETVLTIMDIK
Sbjct: 241 SDPFLQVRILRLLRILGRNDDDSSEAMNDILAQVATNTETSKNVGNAILYETVLTIMDIK 300
Query: 301 SESGLRVLAINILGRFLLNNDKNIRYVALTSLLKTVQTDHNAVQRHRSTIVDCLKDLDVS 360
SESGLRVLAINILGRFLLNNDKNIRYVALTSLLKTVQTDHNAVQRHRSTIVDCLKDLDVS
Sbjct: 301 SESGLRVLAINILGRFLLNNDKNIRYVALTSLLKTVQTDHNAVQRHRSTIVDCLKDLDVS 360
Query: 361 IKRRAMELSFALVNGNNIRGMMKELLYFLDSCEPEFKADCASGIFLAAEKYAPSKRWHID 420
IKRRAMELSFALVNGNNIRGMMKELLYFLDSCEPEFKADCASGIFLAAEKYAPSKRWHID
Sbjct: 361 IKRRAMELSFALVNGNNIRGMMKELLYFLDSCEPEFKADCASGIFLAAEKYAPSKRWHID 420
Query: 421 TIMRVLTTAGSYVRDDAVPNLIQLITNSVEMHAYTVQRLYKAILGDYSQQPLVQVAAWCI 480
TIMRVLTTAGSYVRDDAVPNLIQLITNSVEMHAYTVQRLYKAILGDYSQQPLVQVAAWCI
Sbjct: 421 TIMRVLTTAGSYVRDDAVPNLIQLITNSVEMHAYTVQRLYKAILGDYSQQPLVQVAAWCI 480
Query: 481 GEYGDLLVSGQCEEEEPIQVTEDEVLDILESVLISNMSTSVTRGYALTAIMKLSTRFTCT 540
GEYGDLLVSGQCEEEEPIQVTEDEVLDILESVLISNMSTSVTRGYALTAIMKLSTRFTCT
Sbjct: 481 GEYGDLLVSGQCEEEEPIQVTEDEVLDILESVLISNMSTSVTRGYALTAIMKLSTRFTCT 540
Query: 541 VNRIKKVVSIYGSSIDVELQQRAVEYNALFKKYDHMRSALLERMPVMEKVTTNGPTEIVQ 600
VNRIKKVVSIYGSSIDVELQQRAVEYNALFKKYDHMRSALLERMPVMEKVTTNGPTEIVQ
Sbjct: 541 VNRIKKVVSIYGSSIDVELQQRAVEYNALFKKYDHMRSALLERMPVMEKVTTNGPTEIVQ 600
Query: 601 TNGETEPAPLETKPPPSGPQPTSQANDLLDLLGGNDITPVIPTAPTSKPSSAGGELLDLL 660
TNGETEPAPLETKPPPSGPQPTSQANDLLDLLGGNDITPVIPTAPTSKPSSAGGELLDLL
Sbjct: 601 TNGETEPAPLETKPPPSGPQPTSQANDLLDLLGGNDITPVIPTAPTSKPSSAGGELLDLL 660
Query: 661 GDINLTGAPAAAPAPASVPQISQPPFLLDGLSSQPLFNDIAAGIPSITAYSKNGLKIEFT 720
GDINLTGAPAAAPAPASVPQISQPPFLLDGLSSQPLFNDIAAGIPSITAYSKNGLKIEFT
Sbjct: 661 GDINLTGAPAAAPAPASVPQISQPPFLLDGLSSQPLFNDIAAGIPSITAYSKNGLKIEFT 720
Query: 721 FERSNTNPSVTVITIQASNSTELDMTDFVFQAAVPKTFQLQLLSPSSSIVPAFNTGTITQ 780
FERSNTNPSVTVITIQASNSTELDMTDFVFQAAVPKTFQLQLLSPSSSIVPAFNTGTITQ
Sbjct: 721 FERSNTNPSVTVITIQASNSTELDMTDFVFQAAVPKTFQLQLLSPSSSIVPAFNTGTITQ 780
Query: 781 VIKVLNPQKQQLRMRIKLTYNHKGSAMQDLAEVNNFPPQSWQ 822
VIKVLNPQKQQLRMRIKLTYNHKGSAMQDLAEVNNFPPQSWQ
Sbjct: 781 VIKVLNPQKQQLRMRIKLTYNHKGSAMQDLAEVNNFPPQSWQ 822
>gi|71773010 adaptor-related protein complex 1, gamma 1 subunit
isoform a [Homo sapiens]
Length = 825
Score = 1608 bits (4164), Expect = 0.0
Identities = 822/825 (99%), Positives = 822/825 (99%), Gaps = 3/825 (0%)
Query: 1 MPAPIRLRELIRTIRTARTQAEEREMIQKECAAIRSSFREEDNTYRCRNVAKLLYMHMLG 60
MPAPIRLRELIRTIRTARTQAEEREMIQKECAAIRSSFREEDNTYRCRNVAKLLYMHMLG
Sbjct: 1 MPAPIRLRELIRTIRTARTQAEEREMIQKECAAIRSSFREEDNTYRCRNVAKLLYMHMLG 60
Query: 61 YPAHFGQLECLKLIASQKFTDKRIGYLGAMLLLDERQDVHLLMTNCIKNDLNHSTQFVQG 120
YPAHFGQLECLKLIASQKFTDKRIGYLGAMLLLDERQDVHLLMTNCIKNDLNHSTQFVQG
Sbjct: 61 YPAHFGQLECLKLIASQKFTDKRIGYLGAMLLLDERQDVHLLMTNCIKNDLNHSTQFVQG 120
Query: 121 LALCTLGCMGSSEMCRDLAGEVEKLLKTSNSYLRKKAALCAVHVIRKVPELMEMFLPATK 180
LALCTLGCMGSSEMCRDLAGEVEKLLKTSNSYLRKKAALCAVHVIRKVPELMEMFLPATK
Sbjct: 121 LALCTLGCMGSSEMCRDLAGEVEKLLKTSNSYLRKKAALCAVHVIRKVPELMEMFLPATK 180
Query: 181 NLLNEKNHGVLHTSVVLLTEMCERSPDMLAHFRK---LVPQLVRILKNLIMSGYSPEHDV 237
NLLNEKNHGVLHTSVVLLTEMCERSPDMLAHFRK LVPQLVRILKNLIMSGYSPEHDV
Sbjct: 181 NLLNEKNHGVLHTSVVLLTEMCERSPDMLAHFRKNEKLVPQLVRILKNLIMSGYSPEHDV 240
Query: 238 SGISDPFLQVRILRLLRILGRNDDDSSEAMNDILAQVATNTETSKNVGNAILYETVLTIM 297
SGISDPFLQVRILRLLRILGRNDDDSSEAMNDILAQVATNTETSKNVGNAILYETVLTIM
Sbjct: 241 SGISDPFLQVRILRLLRILGRNDDDSSEAMNDILAQVATNTETSKNVGNAILYETVLTIM 300
Query: 298 DIKSESGLRVLAINILGRFLLNNDKNIRYVALTSLLKTVQTDHNAVQRHRSTIVDCLKDL 357
DIKSESGLRVLAINILGRFLLNNDKNIRYVALTSLLKTVQTDHNAVQRHRSTIVDCLKDL
Sbjct: 301 DIKSESGLRVLAINILGRFLLNNDKNIRYVALTSLLKTVQTDHNAVQRHRSTIVDCLKDL 360
Query: 358 DVSIKRRAMELSFALVNGNNIRGMMKELLYFLDSCEPEFKADCASGIFLAAEKYAPSKRW 417
DVSIKRRAMELSFALVNGNNIRGMMKELLYFLDSCEPEFKADCASGIFLAAEKYAPSKRW
Sbjct: 361 DVSIKRRAMELSFALVNGNNIRGMMKELLYFLDSCEPEFKADCASGIFLAAEKYAPSKRW 420
Query: 418 HIDTIMRVLTTAGSYVRDDAVPNLIQLITNSVEMHAYTVQRLYKAILGDYSQQPLVQVAA 477
HIDTIMRVLTTAGSYVRDDAVPNLIQLITNSVEMHAYTVQRLYKAILGDYSQQPLVQVAA
Sbjct: 421 HIDTIMRVLTTAGSYVRDDAVPNLIQLITNSVEMHAYTVQRLYKAILGDYSQQPLVQVAA 480
Query: 478 WCIGEYGDLLVSGQCEEEEPIQVTEDEVLDILESVLISNMSTSVTRGYALTAIMKLSTRF 537
WCIGEYGDLLVSGQCEEEEPIQVTEDEVLDILESVLISNMSTSVTRGYALTAIMKLSTRF
Sbjct: 481 WCIGEYGDLLVSGQCEEEEPIQVTEDEVLDILESVLISNMSTSVTRGYALTAIMKLSTRF 540
Query: 538 TCTVNRIKKVVSIYGSSIDVELQQRAVEYNALFKKYDHMRSALLERMPVMEKVTTNGPTE 597
TCTVNRIKKVVSIYGSSIDVELQQRAVEYNALFKKYDHMRSALLERMPVMEKVTTNGPTE
Sbjct: 541 TCTVNRIKKVVSIYGSSIDVELQQRAVEYNALFKKYDHMRSALLERMPVMEKVTTNGPTE 600
Query: 598 IVQTNGETEPAPLETKPPPSGPQPTSQANDLLDLLGGNDITPVIPTAPTSKPSSAGGELL 657
IVQTNGETEPAPLETKPPPSGPQPTSQANDLLDLLGGNDITPVIPTAPTSKPSSAGGELL
Sbjct: 601 IVQTNGETEPAPLETKPPPSGPQPTSQANDLLDLLGGNDITPVIPTAPTSKPSSAGGELL 660
Query: 658 DLLGDINLTGAPAAAPAPASVPQISQPPFLLDGLSSQPLFNDIAAGIPSITAYSKNGLKI 717
DLLGDINLTGAPAAAPAPASVPQISQPPFLLDGLSSQPLFNDIAAGIPSITAYSKNGLKI
Sbjct: 661 DLLGDINLTGAPAAAPAPASVPQISQPPFLLDGLSSQPLFNDIAAGIPSITAYSKNGLKI 720
Query: 718 EFTFERSNTNPSVTVITIQASNSTELDMTDFVFQAAVPKTFQLQLLSPSSSIVPAFNTGT 777
EFTFERSNTNPSVTVITIQASNSTELDMTDFVFQAAVPKTFQLQLLSPSSSIVPAFNTGT
Sbjct: 721 EFTFERSNTNPSVTVITIQASNSTELDMTDFVFQAAVPKTFQLQLLSPSSSIVPAFNTGT 780
Query: 778 ITQVIKVLNPQKQQLRMRIKLTYNHKGSAMQDLAEVNNFPPQSWQ 822
ITQVIKVLNPQKQQLRMRIKLTYNHKGSAMQDLAEVNNFPPQSWQ
Sbjct: 781 ITQVIKVLNPQKQQLRMRIKLTYNHKGSAMQDLAEVNNFPPQSWQ 825
>gi|4503843 adaptor-related protein complex 1, gamma 2 subunit [Homo
sapiens]
Length = 785
Score = 941 bits (2433), Expect = 0.0
Identities = 490/821 (59%), Positives = 619/821 (75%), Gaps = 44/821 (5%)
Query: 5 IRLRELIRTIRTARTQAEEREMIQKECAAIRSSFREEDNTYRCRNVAKLLYMHMLGYPAH 64
++L++LI IR A+TQA+ERE+IQKECA IR+SFR+ D +R R +AKLLY+HMLGYPAH
Sbjct: 6 LKLQDLIEEIRGAKTQAQEREVIQKECAHIRASFRDGDPVHRHRQLAKLLYVHMLGYPAH 65
Query: 65 FGQLECLKLIASQKFTDKRIGYLGAMLLLDERQDVHLLMTNCIKNDLNHSTQFVQGLALC 124
FGQ+ECLKLIAS +FTDKR+GYLGAMLLLDER D HLL+TN IKNDL+ Q VQGLALC
Sbjct: 66 FGQMECLKLIASSRFTDKRVGYLGAMLLLDERHDAHLLITNSIKNDLSQGIQPVQGLALC 125
Query: 125 TLGCMGSSEMCRDLAGEVEKLLKTSNSYLRKKAALCAVHVIRKVPELMEMFLPATKNLLN 184
TL MGS+EMCRDLA EVEKLL + Y+RKKA L AVH+IRKVPEL +FLP LL+
Sbjct: 126 TLSTMGSAEMCRDLAPEVEKLLLQPSPYVRKKAILTAVHMIRKVPELSSVFLPPCAQLLH 185
Query: 185 EKNHGVLHTSVVLLTEMCERSPDMLAHFRKLVPQLVRILKNLIMSGYSPEHDVSGISDPF 244
E++HG+L ++ L+TE+CERSP L HFRK+VPQLV IL+ L+ GYS EH +SG+SDPF
Sbjct: 186 ERHHGILLGTITLITELCERSPAALRHFRKVVPQLVHILRTLVTMGYSTEHSISGVSDPF 245
Query: 245 LQVRILRLLRILGRNDDDSSEAMNDILAQVATNTETSKNVGNAILYETVLTIMDIKSESG 304
LQV+ILRLLRILGRN ++SSE MND+LAQVATNT+TS+N GNA+L+ETVLTIMDI+S +G
Sbjct: 246 LQVQILRLLRILGRNHEESSETMNDLLAQVATNTDTSRNAGNAVLFETVLTIMDIRSAAG 305
Query: 305 LRVLAINILGRFLLNNDKNIRYVALTSLLKTVQTDHNAVQRHRSTIVDCLKDLDVSIKRR 364
LRVLA+NILGRFLLN+D+NIRYVALTSLL+ VQ+DH+AVQRHR T+V+CL++ D S+ RR
Sbjct: 306 LRVLAVNILGRFLLNSDRNIRYVALTSLLRLVQSDHSAVQRHRPTVVECLRETDASLSRR 365
Query: 365 AMELSFALVNGNNIRGMMKELLYFLDSCEPEFKADCASGIFLAAEKYAPSKRWHIDTIMR 424
A+ELS ALVN +N+R MM+EL FL+SC P+ +ADCASGI LAAE++AP+KRWHIDTI+
Sbjct: 366 ALELSLALVNSSNVRAMMQELQAFLESCPPDLRADCASGILLAAERFAPTKRWHIDTILH 425
Query: 425 VLTTAGSYVRDDAVPNLIQLITNSVEMHAYTVQRLYKAILGDYSQQPLVQVAAWCIGEYG 484
VLTTAG++VRDDAV NL QLI + E+HAY+V+RLY A+ D SQQPLVQVAAWCIGEYG
Sbjct: 426 VLTTAGTHVRDDAVANLTQLIGGAQELHAYSVRRLYNALAEDISQQPLVQVAAWCIGEYG 485
Query: 485 DLLVSGQCEEEEPIQVTEDEVLDILESVLISNMSTSVTRGYALTAIMKLSTRFTCTVNRI 544
DLL++G CEE EP+QV E+EVL +LE VL S+MS TRGYALTA+MKLSTR NRI
Sbjct: 486 DLLLAGNCEEIEPLQVDEEEVLALLEKVLQSHMSLPATRGYALTALMKLSTRLCGDNNRI 545
Query: 545 KKVVSIYGSSIDVELQQRAVEYNALFKKYDHMRSALLERMPVMEKVTTNGPTEIVQTNGE 604
++VVSIYGS +DVELQQRAVEY+ LF+KYDHMR+A+LE+MP++E+ +GP +
Sbjct: 546 RQVVSIYGSCLDVELQQRAVEYDTLFRKYDHMRAAILEKMPLVER---DGPQADEEAKES 602
Query: 605 TEPAPL-ETKPPPSGPQPTSQANDLLDLLGG--NDITPVIPTAPTSKPSSAGGELLDLLG 661
E A L E P P+ PQ SQ DLLDLL G D+ P S GG L+ LL
Sbjct: 603 KEAAQLSEAAPVPTEPQ-ASQLLDLLDLLDGASGDV-----QHPPHLDPSPGGALVHLL- 655
Query: 662 DINLTGAPAAAPAPASVPQISQPPFLLDGLSSQPLFNDIAAGIPSITAYSKNGLKIEFTF 721
+P + PP A IP + + + G+++ +F
Sbjct: 656 ---------------DLPCVPPPP----------------APIPDLKVFEREGVQLNLSF 684
Query: 722 ERSNTNPSVTVITIQASNSTELDMTDFVFQAAVPKTFQLQLLSPSSSIVPAFNTGTITQV 781
R NP++ +ITI A+N +E D+T F+ QAAVPK+ QLQL +PS + VPA ITQ+
Sbjct: 685 IRPPENPALLLITITATNFSEGDVTHFICQAAVPKSLQLQLQAPSGNTVPARGGLPITQL 744
Query: 782 IKVLNPQKQQLRMRIKLTYNHKGSAMQDLAEVNNFPPQSWQ 822
++LNP K LR++++LTY+H ++Q++ EVNN P +SWQ
Sbjct: 745 FRILNPNKAPLRLKLRLTYDHFHQSVQEIFEVNNLPVESWQ 785
>gi|19913414 adaptor-related protein complex 2, alpha 1 subunit
isoform 1 [Homo sapiens]
Length = 977
Score = 278 bits (712), Expect = 1e-74
Identities = 211/714 (29%), Positives = 372/714 (52%), Gaps = 58/714 (8%)
Query: 7 LRELIRTIRTARTQAEEREMIQKECAAIRSSFREE---DNTYRCRNVAKLLYMHMLGYPA 63
L I IR +++ E + I KE A IRS F+ + D + + V KLL++ +LG+
Sbjct: 13 LAVFISDIRNCKSKEAEIKRINKELANIRSKFKGDKALDGYSKKKYVCKLLFIFLLGHDI 72
Query: 64 HFGQLECLKLIASQKFTDKRIGYLGAMLLLDERQDVHLLMTNCIKNDLNHSTQFVQGLAL 123
FG +E + L++S K+T+K+IGYL +L++ ++ L+ N IKNDL LAL
Sbjct: 73 DFGHMEAVNLLSSNKYTEKQIGYLFISVLVNSNSELIRLINNAIKNDLASRNPTFMCLAL 132
Query: 124 CTLGCMGSSEMCRDLAGEVEKLLKTSNSY--LRKKAALCAVHVIRKVPELMEM--FLPAT 179
+ +GS EM A ++ ++L +S +++ AALC + + + P+L+ M +
Sbjct: 133 HCIANVGSREMGEAFAADIPRILVAGDSMDSVKQSAALCLLRLYKASPDLVPMGEWTARV 192
Query: 180 KNLLNEKNHGVLHTSVVLLTEMCERSPDMLAHFRKLVPQLVRILKNLIMSGYSPEHDVSG 239
+LLN+++ GV+ +V L+T +C+++PD F+ V V L ++ S + D +
Sbjct: 193 VHLLNDQHMGVVTAAVSLITCLCKKNPD---DFKTCVSLAVSRLSRIVSSASTDLQDYTY 249
Query: 240 --ISDPFLQVRILRLLRILGRNDDDSS-----EAMNDILAQVATNTETSK----NVGNAI 288
+ P+L V++LRLL+ +D + E + +L + ++ K N NAI
Sbjct: 250 YFVPAPWLSVKLLRLLQCYPPPEDAAVKGRLVECLETVLNKAQEPPKSKKVQHSNAKNAI 309
Query: 289 LYETVLTIMDIKSESGLRVLAINILGRFLLNNDKNIRYVALTSL--LKTVQTDHNAVQRH 346
L+ET+ I+ SE L V A N LG+FL + + N+RY+AL S+ L + + H AV+ H
Sbjct: 310 LFETISLIIHYDSEPNLLVRACNQLGQFLQHRETNLRYLALESMCTLASSEFSHEAVKTH 369
Query: 347 RSTIVDCLK-DLDVSIKRRAMELSFALVNGNNIRGMMKELLYFLDSCEPEFKADCASGIF 405
T+++ LK + DVS+++RA +L +A+ + +N + ++ E+L +L++ + + + +
Sbjct: 370 IDTVINALKTERDVSVRQRAADLLYAMCDRSNAKQIVSEMLRYLETADYAIREEIVLKVA 429
Query: 406 LAAEKYAPSKRWHIDTIMRVLTTAGSYVRDDAVPNLIQLITNSVEMHAYTVQRLYKAILG 465
+ AEKYA W++DTI+ ++ AG YV ++ ++Q++TN ++ Y + +++A+
Sbjct: 430 ILAEKYAVDYSWYVDTILNLIRIAGDYVSEEVWYRVLQIVTNRDDVQGYAAKTVFEALQA 489
Query: 466 DYSQQPLVQVAAWCIGEYGDLLVSGQCEEEEPIQVTEDEVLDILESVLISNMSTSVTRGY 525
+ +V+V + +GE+G+ L++G P+Q +L S ++ + TR
Sbjct: 490 PACHENMVKVGGYILGEFGN-LIAGDPRSSPPVQ------FSLLHSKF--HLCSVATRAL 540
Query: 526 ALTAIMKLSTRFTCTVNRIKKVVSIYGSSI---DVELQQRAVEYNALFK-KYDHMRSALL 581
L+ +K F T I+ V+ GS + DVELQQRAVEY L + + +L
Sbjct: 541 LLSTYIKFINLFPETKATIQGVLRA-GSQLRNADVELQQRAVEYLTLSSVASTDVLATVL 599
Query: 582 ERMPVMEKVTTNGPTEIVQTNGETEPAPLETKPPPSGPQPTSQANDLLDLLGGNDITPVI 641
E MP + ++ ++ + G + L+ P+S D+ GG + TP
Sbjct: 600 EEMPPFPERESSILAKLKRKKGPGAGSALD----DGRRDPSSN-----DINGGMEPTP-- 648
Query: 642 PTAPTSKPSSAGGELLDLLGDINLTGAPAAAPAPASVPQISQPPFLLDGLSSQP 695
T T PS+ DLLG L AP A PAS + + DG ++QP
Sbjct: 649 STVSTPSPSA------DLLG---LRAAPPPAAPPASAGAGNLLVDVFDGPAAQP 693
>gi|19913416 adaptor-related protein complex 2, alpha 1 subunit
isoform 2 [Homo sapiens]
Length = 955
Score = 278 bits (712), Expect = 1e-74
Identities = 211/714 (29%), Positives = 372/714 (52%), Gaps = 58/714 (8%)
Query: 7 LRELIRTIRTARTQAEEREMIQKECAAIRSSFREE---DNTYRCRNVAKLLYMHMLGYPA 63
L I IR +++ E + I KE A IRS F+ + D + + V KLL++ +LG+
Sbjct: 13 LAVFISDIRNCKSKEAEIKRINKELANIRSKFKGDKALDGYSKKKYVCKLLFIFLLGHDI 72
Query: 64 HFGQLECLKLIASQKFTDKRIGYLGAMLLLDERQDVHLLMTNCIKNDLNHSTQFVQGLAL 123
FG +E + L++S K+T+K+IGYL +L++ ++ L+ N IKNDL LAL
Sbjct: 73 DFGHMEAVNLLSSNKYTEKQIGYLFISVLVNSNSELIRLINNAIKNDLASRNPTFMCLAL 132
Query: 124 CTLGCMGSSEMCRDLAGEVEKLLKTSNSY--LRKKAALCAVHVIRKVPELMEM--FLPAT 179
+ +GS EM A ++ ++L +S +++ AALC + + + P+L+ M +
Sbjct: 133 HCIANVGSREMGEAFAADIPRILVAGDSMDSVKQSAALCLLRLYKASPDLVPMGEWTARV 192
Query: 180 KNLLNEKNHGVLHTSVVLLTEMCERSPDMLAHFRKLVPQLVRILKNLIMSGYSPEHDVSG 239
+LLN+++ GV+ +V L+T +C+++PD F+ V V L ++ S + D +
Sbjct: 193 VHLLNDQHMGVVTAAVSLITCLCKKNPD---DFKTCVSLAVSRLSRIVSSASTDLQDYTY 249
Query: 240 --ISDPFLQVRILRLLRILGRNDDDSS-----EAMNDILAQVATNTETSK----NVGNAI 288
+ P+L V++LRLL+ +D + E + +L + ++ K N NAI
Sbjct: 250 YFVPAPWLSVKLLRLLQCYPPPEDAAVKGRLVECLETVLNKAQEPPKSKKVQHSNAKNAI 309
Query: 289 LYETVLTIMDIKSESGLRVLAINILGRFLLNNDKNIRYVALTSL--LKTVQTDHNAVQRH 346
L+ET+ I+ SE L V A N LG+FL + + N+RY+AL S+ L + + H AV+ H
Sbjct: 310 LFETISLIIHYDSEPNLLVRACNQLGQFLQHRETNLRYLALESMCTLASSEFSHEAVKTH 369
Query: 347 RSTIVDCLK-DLDVSIKRRAMELSFALVNGNNIRGMMKELLYFLDSCEPEFKADCASGIF 405
T+++ LK + DVS+++RA +L +A+ + +N + ++ E+L +L++ + + + +
Sbjct: 370 IDTVINALKTERDVSVRQRAADLLYAMCDRSNAKQIVSEMLRYLETADYAIREEIVLKVA 429
Query: 406 LAAEKYAPSKRWHIDTIMRVLTTAGSYVRDDAVPNLIQLITNSVEMHAYTVQRLYKAILG 465
+ AEKYA W++DTI+ ++ AG YV ++ ++Q++TN ++ Y + +++A+
Sbjct: 430 ILAEKYAVDYSWYVDTILNLIRIAGDYVSEEVWYRVLQIVTNRDDVQGYAAKTVFEALQA 489
Query: 466 DYSQQPLVQVAAWCIGEYGDLLVSGQCEEEEPIQVTEDEVLDILESVLISNMSTSVTRGY 525
+ +V+V + +GE+G+ L++G P+Q +L S ++ + TR
Sbjct: 490 PACHENMVKVGGYILGEFGN-LIAGDPRSSPPVQ------FSLLHSKF--HLCSVATRAL 540
Query: 526 ALTAIMKLSTRFTCTVNRIKKVVSIYGSSI---DVELQQRAVEYNALFK-KYDHMRSALL 581
L+ +K F T I+ V+ GS + DVELQQRAVEY L + + +L
Sbjct: 541 LLSTYIKFINLFPETKATIQGVLRA-GSQLRNADVELQQRAVEYLTLSSVASTDVLATVL 599
Query: 582 ERMPVMEKVTTNGPTEIVQTNGETEPAPLETKPPPSGPQPTSQANDLLDLLGGNDITPVI 641
E MP + ++ ++ + G + L+ P+S D+ GG + TP
Sbjct: 600 EEMPPFPERESSILAKLKRKKGPGAGSALD----DGRRDPSSN-----DINGGMEPTP-- 648
Query: 642 PTAPTSKPSSAGGELLDLLGDINLTGAPAAAPAPASVPQISQPPFLLDGLSSQP 695
T T PS+ DLLG L AP A PAS + + DG ++QP
Sbjct: 649 STVSTPSPSA------DLLG---LRAAPPPAAPPASAGAGNLLVDVFDGPAAQP 693
>gi|27477041 adaptor-related protein complex 2, alpha 2 subunit
[Homo sapiens]
Length = 939
Score = 277 bits (708), Expect = 3e-74
Identities = 214/715 (29%), Positives = 363/715 (50%), Gaps = 69/715 (9%)
Query: 7 LRELIRTIRTARTQAEEREMIQKECAAIRSSFREE---DNTYRCRNVAKLLYMHMLGYPA 63
L I IR +++ E + I KE A IRS F+ + D + + V KLL++ +LG+
Sbjct: 13 LAVFISDIRNCKSKEAEIKRINKELANIRSKFKGDKALDGYSKKKYVCKLLFIFLLGHDI 72
Query: 64 HFGQLECLKLIASQKFTDKRIGYLGAMLLLDERQDVHLLMTNCIKNDLNHSTQFVQGLAL 123
FG +E + L++S ++T+K+IGYL +L++ ++ L+ N IKNDL GLAL
Sbjct: 73 DFGHMEAVNLLSSNRYTEKQIGYLFISVLVNSNSELIRLINNAIKNDLASRNPTFMGLAL 132
Query: 124 CTLGCMGSSEMCRDLAGEVEKLLKTSNSY--LRKKAALCAVHVIRKVPELMEM--FLPAT 179
+ +GS EM AGE+ K+L ++ +++ AALC + + R P+L+ M +
Sbjct: 133 HCIASVGSREMAEAFAGEIPKVLVAGDTMDSVKQSAALCLLRLYRTSPDLVPMGDWTSRV 192
Query: 180 KNLLNEKNHGVLHTSVVLLTEMCERSPDMLAHFRKLVPQLVRILKNLIMSGYSPEHDVSG 239
+LLN+++ GV+ + L+T + +++P+ F+ V V L ++ S + D +
Sbjct: 193 VHLLNDQHLGVVTAATSLITTLAQKNPE---EFKTSVSLAVSRLSRIVTSASTDLQDYTY 249
Query: 240 --ISDPFLQVRILRLLRILGRNDDDS----SEAMNDILAQVATNTETSK----NVGNAIL 289
+ P+L V++LRLL+ D +E + IL + ++ K N NA+L
Sbjct: 250 YFVPAPWLSVKLLRLLQCYPPPDPAVRGRLTECLETILNKAQEPPKSKKVQHSNAKNAVL 309
Query: 290 YETVLTIMDIKSESGLRVLAINILGRFLLNNDKNIRYVALTSL--LKTVQTDHNAVQRHR 347
+E + I+ SE L V A N LG+FL + + N+RY+AL S+ L + + H AV+ H
Sbjct: 310 FEAISLIIHHDSEPNLLVRACNQLGQFLQHRETNLRYLALESMCTLASSEFSHEAVKTHI 369
Query: 348 STIVDCLK-DLDVSIKRRAMELSFALVNGNNIRGMMKELLYFLDSCEPEFKADCASGIFL 406
T+++ LK + DVS+++RA++L +A+ + +N ++ E+L +L++ + + + + +
Sbjct: 370 ETVINALKTERDVSVRQRAVDLLYAMCDRSNAPQIVAEMLSYLETADYSIREEIVLKVAI 429
Query: 407 AAEKYAPSKRWHIDTIMRVLTTAGSYVRDDAVPNLIQLITNSVEMHAYTVQRLYKAILGD 466
AEKYA W++DTI+ ++ AG YV ++ +IQ++ N ++ Y + +++A+
Sbjct: 430 LAEKYAVDYTWYVDTILNLIRIAGDYVSEEVWYRVIQIVINRDDVQGYAAKTVFEALQAP 489
Query: 467 YSQQPLVQVAAWCIGEYGDLLVSGQCEEEEPIQVTEDEVLDILESVLISNMSTSVTRGYA 526
+ LV+V + +GE+G+ L++G IQ +L S ++ + TR
Sbjct: 490 ACHENLVKVGGYILGEFGN-LIAGDPRSSPLIQ------FHLLHSKF--HLCSVPTRALL 540
Query: 527 LTAIMKLSTRFTCTVNRIKKVVSIYGS--SIDVELQQRAVEYNAL--FKKYDHMRSALLE 582
L+ +K F I+ V+ + DVELQQRAVEY L D + + L E
Sbjct: 541 LSTYIKFVNLFPEVKPTIQDVLRSDSQLRNADVELQQRAVEYLRLSTVASTDILATVLEE 600
Query: 583 RMPVMEKVTT--------NGPTEI-----------VQTNGETEPAPLETKPPPSGPQPTS 623
P E+ ++ GP+ + V NG EPAP T S P P++
Sbjct: 601 MPPFPERESSILAKLKKKKGPSTVTDLEDTKRDRSVDVNGGPEPAPASTS-AVSTPSPSA 659
Query: 624 QANDLLDLLGGNDITPVIPTAPTSKPSSAGGELLDLLGDINLTGAPAAAP-APAS 677
DLLG P AP P S+GG LL D+ A AP AP S
Sbjct: 660 ------DLLG----LGAAPPAPAGPPPSSGGS--GLLVDVFSDSASVVAPLAPGS 702
>gi|37675283 adaptor-related protein complex 4, epsilon 1 subunit
[Homo sapiens]
Length = 1137
Score = 238 bits (606), Expect = 2e-62
Identities = 162/588 (27%), Positives = 295/588 (50%), Gaps = 28/588 (4%)
Query: 6 RLRELIRTIRTARTQAEEREMIQKECAAIRSSFREEDNTYRCRN--VAKLLYMHMLGYPA 63
RL L+R I ++ EE ++IQ+E ++++++ T + + +L+Y MLGY A
Sbjct: 35 RLGSLVRGITALTSKHEEEKLIQQELSSLKATVSAPTTTLKMMKECMVRLIYCEMLGYDA 94
Query: 64 HFGQLECLKLIASQKFTDKRIGYLGAMLLLDERQDVHLLMTNCIKNDLNHSTQFVQGLAL 123
FG + +KL +KR+GYL L L E ++ LL+ N + DL + +AL
Sbjct: 95 SFGYIHAIKLAQQGNLLEKRVGYLAVSLFLHESHELLLLLVNTVVKDLQSTNLVEVCMAL 154
Query: 124 CTLGCMGSSEMCRDLAGEVEKLLKTSNSYLRKKAALCAVHVIRKVPELMEMFLPATKNLL 183
+ + EM + +E L+ S +R+KA L P ++ + L
Sbjct: 155 TVVSQIFPCEMIPAVLPLIEDKLQHSKEIVRRKAVLALYKFHLIAPNQVQHIHIKFRKAL 214
Query: 184 NEKNHGVLHTSVVLLTEMCERSPDMLAHFRKLVPQLVRILKNLIMSGYSPEHDVSGISDP 243
+++ GV+ S+ + M + + + ++ L V ILK ++ E + + P
Sbjct: 215 CDRDVGVMAASLHIYLRMIKENS---SGYKDLTGSFVTILKQVVGGKLPVEFNYHSVPAP 271
Query: 244 FLQVRILRLLRILGRNDDDSSEAMNDILAQVATNTETSKNVGNAILYETVLTIMDIKSES 303
+LQ+++LR+L +LG++D +SE M D+L + E + NV AIL+E V T+ I +S
Sbjct: 272 WLQIQLLRILGLLGKDDQRTSELMYDVLDESLRRAELNHNVTYAILFECVHTVYSIYPKS 331
Query: 304 GLRVLAINILGRFLLNNDKNIRYVALTSLLKTVQTDHNAVQRHRSTIVDCLKDLDVSIKR 363
L A +G+F+L+ N++Y+ L +L +Q D +H+ TI++CL D IKR
Sbjct: 332 ELLEKAAKCIGKFVLSPKINLKYLGLKALTYVIQQDPTLALQHQMTIIECLDHPDPIIKR 391
Query: 364 RAMELSFALVNGNNIRGMMKELLYFLDSCEPEFK-ADCASGIFLAAEKYAPSKRWHIDTI 422
+EL + + N NI +++++L +L + E+ + I AEKYAP W I T+
Sbjct: 392 ETLELLYRITNAQNITVIVQKMLEYLHQSKEEYVIVNLVGKIAELAEKYAPDNAWFIQTM 451
Query: 423 MRVLTTAGSYVRDDAVPNLIQLI-------TNSVEMHAYTVQRLYKAIL---GDYSQQPL 472
V + G + D N ++L+ T ++ Y VQ Y +L + Q
Sbjct: 452 NAVFSVGGDVMHPDIPNNFLRLLAEGFDDETEDQQLRLYAVQS-YLTLLDMENVFYPQRF 510
Query: 473 VQVAAWCIGEYGDLLVSGQCEEEEPIQVTEDEVLDILESVLISNMSTSVTRGYALTAIMK 532
+QV +W +GEY LL ++E P +EV+ L +L+++ +S T+ + + A+ K
Sbjct: 511 LQVMSWVLGEYSYLL-----DKETP-----EEVIAKLYKLLMNDSVSSETKAWLIAAVTK 560
Query: 533 LSTRFTCTVNRIKKVVSIYGSSIDVELQQRAVEYNALFKKYDHMRSAL 580
L+++ + N +++++ + S+D ++Q A E L + + M+S L
Sbjct: 561 LTSQ-AHSSNTVERLIHEFTISLDTCMRQHAFELKHLHENVELMKSLL 607
>gi|117553580 adaptor-related protein complex 3, delta 1 subunit
isoform 2 [Homo sapiens]
Length = 1153
Score = 170 bits (431), Expect = 4e-42
Identities = 158/696 (22%), Positives = 304/696 (43%), Gaps = 93/696 (13%)
Query: 7 LRELIRTIRTARTQAEEREMIQKECAAIRSSFREEDNTYRCRNVAKLLYMHMLGYPAHFG 66
L++L+R IR + +E + I + I+ ++++ + V KL Y+ MLGY +
Sbjct: 18 LQDLVRGIRNHKE--DEAKYISQCIDEIKQELKQDNIAVKANAVCKLTYLQMLGYDISWA 75
Query: 67 QLECLKLIASQKFTDKRIGYLGAMLLLDERQDVHLLMTNCIKNDLNHSTQFVQGLALCTL 126
++++++ KFT KRIGYL A E DV +L TN I+ DL+ +Q+ G+AL L
Sbjct: 76 AFNIIEVMSASKFTFKRIGYLAASQSFHEGTDVIMLTTNQIRKDLSSPSQYDTGVALTGL 135
Query: 127 GCMGSSEMCRDLAGEVEKLLKTSNSYLRKKAALCAVHVIRKVPELMEMFLPATKNLLNEK 186
C + ++ RDLA ++ L+ + Y+RKKA L V K PE + P K L +
Sbjct: 136 SCFVTPDLARDLANDIMTLMSHTKPYIRKKAVLIMYKVFLKYPESLRPAFPRLKEKLEDP 195
Query: 187 NHGVLHTSVVLLTEMCERSPDMLAHFRKLVPQLVRILKNLIMSGYSPEHDVSGISDPFLQ 246
+ GV +V ++ E+ R+P ++ L P +++ + ++ ++
Sbjct: 196 DPGVQSAAVNVICELARRNP---KNYLSLAPLFFKLM--------------TSSTNNWVL 238
Query: 247 VRILRLLRILGRNDDDSSEAMNDILAQVATNTETSKNVGNAILYETVLTIMDI------- 299
++I++L L + + + + L + +T ++LYE V T++ +
Sbjct: 239 IKIIKLFGALTPLEPRLGKKLIEPLTNLIHSTSAM-----SLLYECVNTVIAVLISLSSG 293
Query: 300 -KSESGLRVLAINILGRFLLNNDKNIRYVALTSLLKTVQTDHNAVQRHRSTIVDCLKDLD 358
+ S L + L + ++D+N++Y+ L ++ K ++T +VQ H+ I+ CL D D
Sbjct: 294 MPNHSASIQLCVQKLRILIEDSDQNLKYLGLLAMSKILKTHPKSVQSHKDLILQCLDDKD 353
Query: 359 VSIKRRAMELSFALVNGNNIRGMMKELLYFLDSCEPEFKAD---------CASGIFLAAE 409
SI+ RA++L + +V+ N+ ++K+L+ +D E D C+ +
Sbjct: 354 ESIRLRALDLLYGMVSKKNLMEIVKKLMTHVDKAEGTTYRDELLTKIIDICSQSNY---- 409
Query: 410 KYAPSKRWHIDTIMRVLTTAGSYVRDDAVPNLIQLITNSVEMHAYTVQRLYKA-----IL 464
+Y + W+I ++ + G+ ++ + + + V ++ +L
Sbjct: 410 QYITNFEWYISILVELTRLEGTRHGHLIAAQMLDVAIRVKAIRKFAVSQMSALLDSAHLL 469
Query: 465 GDYSQQ----PLVQVAAWCIGEYGDLLVSGQCEEEEPIQ------------VTEDEVLDI 508
+Q+ ++ AAW GE+ + L E ++ V V+ +
Sbjct: 470 ASSTQRNGICEVLYAAAWICGEFSEHLQEPHHTLEAMLRPRVTTLPGHIQAVYVQNVVKL 529
Query: 509 LESVLISNMSTSVTRG-YALTAIMKLSTRFTCTVNRIKKVVSIYGSSIDVELQQRAVEYN 567
S+L G A+T +M V+R+ + V S D+E+Q+RA +
Sbjct: 530 YASILQQKEQAGEAEGAQAVTQLM---------VDRLPQFV----QSADLEVQERA---S 573
Query: 568 ALFKKYDHMRSALLERMPVMEKVTTNGPTEIVQTNGETEPAPLETKPPPSGPQPTSQAND 627
+ + H++ + +PV E+V+ E+ P + P P G + N+
Sbjct: 574 CILQLVKHIQKLQAKDVPVAEEVSALFAGEL----NPVAPKAQKKVPVPEGLDLDAWINE 629
Query: 628 LLDLLGGNDITPVI------PTAPTSKPSSAGGELL 657
L D P P +PS A E L
Sbjct: 630 PLSDSESEDERPRAVFHEEEQRRPKHRPSEADEEEL 665
>gi|117553584 adaptor-related protein complex 3, delta 1 subunit
isoform 1 [Homo sapiens]
Length = 1112
Score = 95.5 bits (236), Expect = 2e-19
Identities = 52/153 (33%), Positives = 87/153 (56%), Gaps = 2/153 (1%)
Query: 7 LRELIRTIRTARTQAEEREMIQKECAAIRSSFREEDNTYRCRNVAKLLYMHMLGYPAHFG 66
L++L+R IR + +E + I + I+ ++++ + V KL Y+ MLGY +
Sbjct: 18 LQDLVRGIRNHKE--DEAKYISQCIDEIKQELKQDNIAVKANAVCKLTYLQMLGYDISWA 75
Query: 67 QLECLKLIASQKFTDKRIGYLGAMLLLDERQDVHLLMTNCIKNDLNHSTQFVQGLALCTL 126
++++++ KFT KRIGYL A E DV +L TN I+ DL+ +Q+ G+AL L
Sbjct: 76 AFNIIEVMSASKFTFKRIGYLAASQSFHEGTDVIMLTTNQIRKDLSSPSQYDTGVALTGL 135
Query: 127 GCMGSSEMCRDLAGEVEKLLKTSNSYLRKKAAL 159
C + ++ RDLA ++ L+ + Y+RKKA L
Sbjct: 136 SCFVTPDLARDLANDIMTLMSHTKPYIRKKAKL 168
Score = 69.7 bits (169), Expect = 1e-11
Identities = 86/416 (20%), Positives = 169/416 (40%), Gaps = 69/416 (16%)
Query: 287 AILYETVLTIMDI--------KSESGLRVLAINILGRFLLNNDKNIRYVALTSLLKTVQT 338
++LYE V T++ + + S L + L + ++D+N++Y+ L ++ K ++T
Sbjct: 183 SLLYECVNTVIAVLISLSSGMPNHSASIQLCVQKLRILIEDSDQNLKYLGLLAMSKILKT 242
Query: 339 DHNAVQRHRSTIVDCLKDLDVSIKRRAMELSFALVNGNNIRGMMKELLYFLDSCEPEFKA 398
+VQ H+ I+ CL D D SI+ RA++L + +V+ N+ ++K+L+ +D E
Sbjct: 243 HPKSVQSHKDLILQCLDDKDESIRLRALDLLYGMVSKKNLMEIVKKLMTHVDKAEGTTYR 302
Query: 399 D---------CASGIFLAAEKYAPSKRWHIDTIMRVLTTAGSYVRDDAVPNLIQLITNSV 449
D C+ + +Y + W+I ++ + G+ ++ +
Sbjct: 303 DELLTKIIDICSQSNY----QYITNFEWYISILVELTRLEGTRHGHLIAAQMLDVAIRVK 358
Query: 450 EMHAYTVQRLYKA-----ILGDYSQQ----PLVQVAAWCIGEYGDLLVSGQCEEEEPIQ- 499
+ + V ++ +L +Q+ ++ AAW GE+ + L E ++
Sbjct: 359 AIRKFAVSQMSALLDSAHLLASSTQRNGICEVLYAAAWICGEFSEHLQEPHHTLEAMLRP 418
Query: 500 -----------VTEDEVLDILESVLISNMSTSVTRG-YALTAIMKLSTRFTCTVNRIKKV 547
V V+ + S+L G A+T +M V+R+ +
Sbjct: 419 RVTTLPGHIQAVYVQNVVKLYASILQQKEQAGEAEGAQAVTQLM---------VDRLPQF 469
Query: 548 VSIYGSSIDVELQQRAVEYNALFKKYDHMRSALLERMPVMEKVTTNGPTEIVQTNGETEP 607
V S D+E+Q+RA + + + H++ + +PV E+V+ E+ P
Sbjct: 470 V----QSADLEVQERA---SCILQLVKHIQKLQAKDVPVAEEVSALFAGEL----NPVAP 518
Query: 608 APLETKPPPSGPQPTSQANDLLDLLGGNDITPVI------PTAPTSKPSSAGGELL 657
+ P P G + N+ L D P P +PS A E L
Sbjct: 519 KAQKKVPVPEGLDLDAWINEPLSDSESEDERPRAVFHEEEQRRPKHRPSEADEEEL 574
>gi|22027653 adaptor-related protein complex 1 beta 1 subunit
isoform b [Homo sapiens]
Length = 942
Score = 93.6 bits (231), Expect = 7e-19
Identities = 178/799 (22%), Positives = 321/799 (40%), Gaps = 127/799 (15%)
Query: 82 KRIGYLGAMLLLDERQDVHLLMTNCIKNDLNHSTQFVQGLALCTLGCMGSSEMCRDLAGE 141
K++ YL M + D+ ++ N D ++ LA+ T+GC+ ++ L
Sbjct: 66 KKLVYLYLMNYAKSQPDMAIMAVNTFVKDCEDPNPLIRALAVRTMGCIRVDKITEYLCEP 125
Query: 142 VEKLLKTSNSYLRKKAALCAVHVIRKVPELME--MFLPATKNLLNEKNHGVLHTSVVLLT 199
+ K LK + Y+RK AA+C + +L+E FL K+L+++ N V+ +V L+
Sbjct: 126 LRKCLKDEDPYVRKTAAVCVAKLHDINAQLVEDQGFLDTLKDLISDSNPMVVANAVAALS 185
Query: 200 EMCERSPDMLAHFRKLVPQLVRILKNLIMSGYSPEHDVSGISDPFLQVRILRLLRILGRN 259
E+ E P ++ L PQ + L + + Q+ IL L
Sbjct: 186 EIAESHPS--SNLLDLNPQSINKLLTALNE-----------CTEWGQIFILDCLANYMPK 232
Query: 260 DDDSSEAMNDILAQVATNTETSKNVGNAILYETVLTIMDIKSE------SGLRVLAINIL 313
DD +++ I +V + + + ++ M++ S+ + L+ LA ++
Sbjct: 233 DDREAQS---ICERVTPRLSHANSAVVLSAVKVLMKFMEMLSKDLDYYGTLLKKLAPPLV 289
Query: 314 GRFLLNNDKNIRYVALTSLLKTVQTDHNAVQRHRSTIVDCLKDLDVSIKRRAMELSFALV 373
LL+ + ++YVAL ++ VQ + +H + + + +K +++ L
Sbjct: 290 --TLLSAEPELQYVALRNINLIVQ-KRPEILKHEMKVFFVKYNDPIYVKLEKLDIMIRLA 346
Query: 374 NGNNIRGMMKELLYFLDSCEPEFKADCASGIFLAAEKYAPSKRWHIDTIMRVLTTAGSYV 433
+ NI ++ EL + + +F I A K S + T++ ++ T +YV
Sbjct: 347 SQANIAQVLAELKEYATEVDVDFVRKAVRAIGRCAIKVEQSAERCVSTLLDLIQTKVNYV 406
Query: 434 RDDAVPNLIQLITNSVEMHAYTVQRLYKAILGDYSQQPLVQVA-AWCIGEYGDLLVSGQC 492
+A+ + + + + L + + D +P + A W +GEY + +
Sbjct: 407 VQEAIVVIKDIFRKYPNKYESVIATLCENL--DSLDEPEARAAMIWIVGEYAERI----- 459
Query: 493 EEEEPIQVTEDEVLDILESVL--ISNMSTSVTRGYALTAIMKLSTRF-TCTVNRIKKVVS 549
D ++LES L + ST V + LTAI+KL + T T +++V+S
Sbjct: 460 ----------DNADELLESFLEGFHDESTQV-QLQLLTAIVKLFLKKPTETQELVQQVLS 508
Query: 550 IYGSSID-VELQQRAVEYNALF-------------------KKYDHMRSALLERM----P 585
+ D +L+ R Y L ++ D + LL+ +
Sbjct: 509 LATQDSDNPDLRDRGYIYWRLLSTDPVAAKEVVLAEKPLISEETDLIEPTLLDELICYIG 568
Query: 586 VMEKVTTNGPTEIVQ--------------TNGETEPAPLETKP--PPSGPQP--TSQAND 627
+ V P+ V+ + E+ +P ET P P G QP D
Sbjct: 569 TLASVYHKPPSAFVEGGRGVVHKSLPPRTASSESAESP-ETAPTGAPPGEQPDVIPAQGD 627
Query: 628 LLDLLGGNDITPVIPTAPTSKPSSAGGELLDLLG---DINLTGAPAAAPAPASVPQISQP 684
LL L D+ P + P + S G +DLLG D + G AP A+VP
Sbjct: 628 LLGDLLNLDLGPPVSGPPLATSSVQMG-AVDLLGGGLDSLIGGTNFVAPPTAAVPANLGA 686
Query: 685 PFLLDGLSSQPLFNDIAAGIPSIT------------AYSKNGLKIEFTFERSNTNPSVTV 732
P G LF D+ +G+ +++ A GL+I TF R + S
Sbjct: 687 PI---GSGLSDLF-DLTSGVGTLSGSYVAPKAVWLPAMKAKGLEISGTFTRQVGSIS--- 739
Query: 733 ITIQASNSTELDMTDFVFQ------AAVPKTFQLQL---LSPSSSIVPAFNTGTITQVIK 783
+ +Q +N MTDF Q P T LQ+ LSP+ ++ + T+ V+K
Sbjct: 740 MDLQLTNKALQVMTDFAIQFNRNSFGLAPAT-PLQVHAPLSPNQTVEISLPLSTVGSVMK 798
Query: 784 V--LNPQKQQLRMRIKLTY 800
+ LN + ++ I + Y
Sbjct: 799 MEPLNNLQVAVKNNIDVFY 817
>gi|22027651 adaptor-related protein complex 1 beta 1 subunit
isoform a [Homo sapiens]
Length = 949
Score = 92.4 bits (228), Expect = 1e-18
Identities = 180/805 (22%), Positives = 323/805 (40%), Gaps = 132/805 (16%)
Query: 82 KRIGYLGAMLLLDERQDVHLLMTNCIKNDLNHSTQFVQGLALCTLGCMGSSEMCRDLAGE 141
K++ YL M + D+ ++ N D ++ LA+ T+GC+ ++ L
Sbjct: 66 KKLVYLYLMNYAKSQPDMAIMAVNTFVKDCEDPNPLIRALAVRTMGCIRVDKITEYLCEP 125
Query: 142 VEKLLKTSNSYLRKKAALCAVHVIRKVPELME--MFLPATKNLLNEKNHGVLHTSVVLLT 199
+ K LK + Y+RK AA+C + +L+E FL K+L+++ N V+ +V L+
Sbjct: 126 LRKCLKDEDPYVRKTAAVCVAKLHDINAQLVEDQGFLDTLKDLISDSNPMVVANAVAALS 185
Query: 200 EMCERSPDMLAHFRKLVPQLVRILKNLIMSGYSPEHDVSGISDPFLQVRILRLLRILGRN 259
E+ E P ++ L PQ + L + + Q+ IL L
Sbjct: 186 EIAESHPS--SNLLDLNPQSINKLLTALNE-----------CTEWGQIFILDCLANYMPK 232
Query: 260 DDDSSEAMNDILAQVATNTETSKNVGNAILYETVLTIMDIKSE------SGLRVLAINIL 313
DD +++ I +V + + + ++ M++ S+ + L+ LA ++
Sbjct: 233 DDREAQS---ICERVTPRLSHANSAVVLSAVKVLMKFMEMLSKDLDYYGTLLKKLAPPLV 289
Query: 314 GRFLLNNDKNIRYVALTSLLKTVQTDHNAVQRHRSTIVDCLKDLDVSIKRRAMELSFALV 373
LL+ + ++YVAL ++ VQ + +H + + + +K +++ L
Sbjct: 290 --TLLSAEPELQYVALRNINLIVQ-KRPEILKHEMKVFFVKYNDPIYVKLEKLDIMIRLA 346
Query: 374 NGNNIRGMMKELLYFLDSCEPEFKADCASGIFLAAEKYAPSKRWHIDTIMRVLTTAGSYV 433
+ NI ++ EL + + +F I A K S + T++ ++ T +YV
Sbjct: 347 SQANIAQVLAELKEYATEVDVDFVRKAVRAIGRCAIKVEQSAERCVSTLLDLIQTKVNYV 406
Query: 434 RDDAVPNLIQLITNSVEMHAYTVQRLYKAILGDYSQQPLVQVA-AWCIGEYGDLLVSGQC 492
+A+ + + + + L + + D +P + A W +GEY + +
Sbjct: 407 VQEAIVVIKDIFRKYPNKYESVIATLCENL--DSLDEPEARAAMIWIVGEYAERI----- 459
Query: 493 EEEEPIQVTEDEVLDILESVL--ISNMSTSVTRGYALTAIMKLSTRF-TCTVNRIKKVVS 549
D ++LES L + ST V + LTAI+KL + T T +++V+S
Sbjct: 460 ----------DNADELLESFLEGFHDESTQV-QLQLLTAIVKLFLKKPTETQELVQQVLS 508
Query: 550 IYGSSID-VELQQRAVEYNALF-------------------KKYDHMRSALLERM----P 585
+ D +L+ R Y L ++ D + LL+ +
Sbjct: 509 LATQDSDNPDLRDRGYIYWRLLSTDPVAAKEVVLAEKPLISEETDLIEPTLLDELICYIG 568
Query: 586 VMEKVTTNGPTEIVQ--------------TNGETEPAPLETKP--PPSGPQP--TSQAND 627
+ V P+ V+ + E+ +P ET P P G QP D
Sbjct: 569 TLASVYHKPPSAFVEGGRGVVHKSLPPRTASSESAESP-ETAPTGAPPGEQPDVIPAQGD 627
Query: 628 LLDLLGGNDITPVI---PTAPTSKPSSA----GGELLDLLGD--INLTGAPAAAPAPASV 678
LL L D+ P + P A +S A GG L L+GD + G AP A+V
Sbjct: 628 LLGDLLNLDLGPPVSGPPLATSSVQMGAVDLLGGGLDSLMGDEPEGIGGTNFVAPPTAAV 687
Query: 679 PQISQPPFLLDGLSSQPLFNDIAAGIPSIT------------AYSKNGLKIEFTFERSNT 726
P P G LF D+ +G+ +++ A GL+I TF R
Sbjct: 688 PANLGAPI---GSGLSDLF-DLTSGVGTLSGSYVAPKAVWLPAMKAKGLEISGTFTRQVG 743
Query: 727 NPSVTVITIQASNSTELDMTDFVFQ------AAVPKTFQLQL---LSPSSSIVPAFNTGT 777
+ S + +Q +N MTDF Q P T LQ+ LSP+ ++ + T
Sbjct: 744 SIS---MDLQLTNKALQVMTDFAIQFNRNSFGLAPAT-PLQVHAPLSPNQTVEISLPLST 799
Query: 778 ITQVIKV--LNPQKQQLRMRIKLTY 800
+ V+K+ LN + ++ I + Y
Sbjct: 800 VGSVMKMEPLNNLQVAVKNNIDVFY 824
>gi|9558729 golgi associated, gamma adaptin ear containing, ARF
binding protein 1 isoform 1 [Homo sapiens]
Length = 639
Score = 92.0 bits (227), Expect = 2e-18
Identities = 72/251 (28%), Positives = 118/251 (47%), Gaps = 29/251 (11%)
Query: 600 QTNGETEP-------AP-LETKPPPSGPQPTSQANDLLDLLGGNDITPVIPTAPTS---- 647
Q++ TEP AP +E++PP P S D LDLLG + +P
Sbjct: 386 QSSDATEPPAPALAQAPSMESRPPAQTSLPASSGLDDLDLLGKTLLQQSLPPESQQVRWE 445
Query: 648 -KPSSAGGELLDLLGDINLTGAPAAA---------PAPASVPQISQPPFLLDGLSSQPLF 697
+ + L DL + +P+++ P P PQ P L + PL
Sbjct: 446 KQQPTPRLTLRDLQNKSSSCSSPSSSATSLLHTVSPEPPRPPQQPVPTELSLASITVPLE 505
Query: 698 NDIAAGIPSITAYSKNGLKIEFTFERSNT--NPSVTVITIQASNSTELDMTDFVFQAAVP 755
+ + I +T Y ++G +I F F R V V+ + ++ + + VFQ+AVP
Sbjct: 506 SIKPSNILPVTVYDQHGFRILFHFARDPLPGRSDVLVVVVSMLSTAPQPIRNIVFQSAVP 565
Query: 756 KTFQLQLLSPSSSIVPAFNT----GTITQVIKVLNPQKQQLRMRIKLTYNHKGSAMQDLA 811
K +++L PS + +PAFN ITQV+ + NPQK+++R+R KLT+ ++
Sbjct: 566 KVMKVKLQPPSGTELPAFNPIVHPSAITQVLLLANPQKEKVRLRYKLTFTMGDQTYNEMG 625
Query: 812 EVNNF-PPQSW 821
+V+ F PP++W
Sbjct: 626 DVDQFPPPETW 636
>gi|48527952 golgi associated, gamma adaptin ear containing, ARF
binding protein 1 isoform 2 [Homo sapiens]
Length = 552
Score = 92.0 bits (227), Expect = 2e-18
Identities = 72/251 (28%), Positives = 118/251 (47%), Gaps = 29/251 (11%)
Query: 600 QTNGETEP-------AP-LETKPPPSGPQPTSQANDLLDLLGGNDITPVIPTAPTS---- 647
Q++ TEP AP +E++PP P S D LDLLG + +P
Sbjct: 299 QSSDATEPPAPALAQAPSMESRPPAQTSLPASSGLDDLDLLGKTLLQQSLPPESQQVRWE 358
Query: 648 -KPSSAGGELLDLLGDINLTGAPAAA---------PAPASVPQISQPPFLLDGLSSQPLF 697
+ + L DL + +P+++ P P PQ P L + PL
Sbjct: 359 KQQPTPRLTLRDLQNKSSSCSSPSSSATSLLHTVSPEPPRPPQQPVPTELSLASITVPLE 418
Query: 698 NDIAAGIPSITAYSKNGLKIEFTFERSNT--NPSVTVITIQASNSTELDMTDFVFQAAVP 755
+ + I +T Y ++G +I F F R V V+ + ++ + + VFQ+AVP
Sbjct: 419 SIKPSNILPVTVYDQHGFRILFHFARDPLPGRSDVLVVVVSMLSTAPQPIRNIVFQSAVP 478
Query: 756 KTFQLQLLSPSSSIVPAFNT----GTITQVIKVLNPQKQQLRMRIKLTYNHKGSAMQDLA 811
K +++L PS + +PAFN ITQV+ + NPQK+++R+R KLT+ ++
Sbjct: 479 KVMKVKLQPPSGTELPAFNPIVHPSAITQVLLLANPQKEKVRLRYKLTFTMGDQTYNEMG 538
Query: 812 EVNNF-PPQSW 821
+V+ F PP++W
Sbjct: 539 DVDQFPPPETW 549
>gi|9558751 ADP-ribosylation factor binding protein 2 [Homo sapiens]
Length = 613
Score = 79.0 bits (193), Expect = 2e-14
Identities = 61/207 (29%), Positives = 99/207 (47%), Gaps = 38/207 (18%)
Query: 649 PSSA---GGELLDLLGDINLTGAPAAAPAPASVPQISQ-------PPF------------ 686
PSS+ GG + + D NL +A PAP + +SQ PP
Sbjct: 399 PSSSTLPGGGVQNPSADRNLLDLLSAQPAPCPLNYVSQKSVPKEVPPGTKSSPGWSWEAG 458
Query: 687 -LLDGLSSQ---------PLFNDIAAGIPSITAYSKNGLKIEFTFERSNT--NPSVTVIT 734
L SSQ PL + + +P + Y +NG +I F ++ +P V V+
Sbjct: 459 PLAPSPSSQNTPLAQVFVPLESVKPSSLPPLIVYDRNGFRILLHFSQTGAPGHPEVQVLL 518
Query: 735 IQASNSTELDMTDFVFQAAVPKTFQLQLLSPSSSIVPAFNT----GTITQVIKVLNPQKQ 790
+ ++ + D +FQ AVPK+ +++L SSS +PAF+ I+Q++ + NP K+
Sbjct: 519 LTMMSTAPQPVWDIMFQVAVPKSMRVKLQPASSSKLPAFSPLMPPAVISQMLLLDNPHKE 578
Query: 791 QLRMRIKLTYNHKGSAMQDLAEVNNFP 817
+R+R KLT+N G ++ EV +FP
Sbjct: 579 PIRLRYKLTFNQGGQPFSEVGEVKDFP 605
>gi|71773106 adaptor-related protein complex 2, beta 1 subunit
isoform a [Homo sapiens]
Length = 951
Score = 77.8 bits (190), Expect = 4e-14
Identities = 145/676 (21%), Positives = 273/676 (40%), Gaps = 76/676 (11%)
Query: 82 KRIGYLGAMLLLDERQDVHLLMTNCIKNDLNHSTQFVQGLALCTLGCMGSSEMCRDLAGE 141
K++ YL M + D+ ++ N D ++ LA+ T+GC+ ++ L
Sbjct: 66 KKLVYLYLMNYAKSQPDMAIMAVNSFVKDCEDPNPLIRALAVRTMGCIRVDKITEYLCEP 125
Query: 142 VEKLLKTSNSYLRKKAALCA--VHVIRKVPELMEMFLPATKNLLNEKNHGVLHTSVVLLT 199
+ K LK + Y+RK AA+C +H I + FL + ++L+ + N V+ +V L+
Sbjct: 126 LRKCLKDEDPYVRKTAAVCVAKLHDINAQMVEDQGFLDSLRDLIADSNPMVVANAVAALS 185
Query: 200 EMCERSPDMLAHFRKLVPQLVRILKNLIMSGYSPEHDVSGISDPFLQVRILRLLRILGRN 259
E+ E P+ ++ L PQ + L + + Q+ IL L
Sbjct: 186 EISESHPN--SNLLDLNPQNINKLLTALNE-----------CTEWGQIFILDCLSNYNPK 232
Query: 260 DDDSSEAMNDILAQVATNTETSKNVGNAILYETVLTIMD----IKSESGLRVLAINILGR 315
DD ++++ + + T + +A++ V +M + +S + + L
Sbjct: 233 DDREAQSICERV------TPRLSHANSAVVLSAVKVLMKFLELLPKDSDYYNMLLKKLAP 286
Query: 316 ---FLLNNDKNIRYVALTSLLKTVQTDHNAVQRHRSTIVDCLKDLDVSIKRRAMELSFAL 372
LL+ + ++YVAL ++ VQ +++ D + +K +++ L
Sbjct: 287 PLVTLLSGEPEVQYVALRNINLIVQKRPEILKQEIKVFFVKYND-PIYVKLEKLDIMIRL 345
Query: 373 VNGNNIRGMMKELLYFLDSCEPEFKADCASGIFLAAEKYAPSKRWHIDTIMRVLTTAGSY 432
+ NI ++ EL + + +F I A K S + T++ ++ T +Y
Sbjct: 346 ASQANIAQVLAELKEYATEVDVDFVRKAVRAIGRCAIKVEQSAERCVSTLLDLIQTKVNY 405
Query: 433 VRDDAVPNLIQLITNSVEMHAYTVQRLYKAILGDYSQQPLVQVA-AWCIGEYGDLLVSGQ 491
V +A+ + + + + L + + D +P + A W +GEY + +
Sbjct: 406 VVQEAIVVIRDIFRKYPNKYESIIATLCENL--DSLDEPDARAAMIWIVGEYAERI---- 459
Query: 492 CEEEEPIQVTEDEVLDILESVL--ISNMSTSVTRGYALTAIMKLSTRFTC-TVNRIKKVV 548
D ++LES L + ST V + LTAI+KL + T +++V+
Sbjct: 460 -----------DNADELLESFLEGFHDESTQV-QLTLLTAIVKLFLKKPSETQELVQQVL 507
Query: 549 SIYGSSID-VELQQRAVEYNALFK--KYDHMRSALLERMPVMEKVTTNGPT---EIVQTN 602
S+ D +L+ R Y L L E+ + E+ PT E++
Sbjct: 508 SLATQDSDNPDLRDRGYIYWRLLSTDPVTAKEVVLSEKPLISEETDLIEPTLLDELICHI 567
Query: 603 GETEPAPLETKPPPSGPQPTSQAN-DLLDLLGGNDITPVIPTAPTSKPSSAGGELL---- 657
G A + KPP + + + + L + G+ P T+ + +++
Sbjct: 568 GSL--ASVYHKPPNAFVEGSHGIHRKHLPIHHGSTDAGDSPVGTTTATNLEQPQVIPSQG 625
Query: 658 DLLGD-INLTGAPAAAPAPASVPQISQPPF----LLDGLSSQPLFNDIAAGIPSITAYSK 712
DLLGD +NL P P +VPQ+S LL G L +D+ GI A +
Sbjct: 626 DLLGDLLNLDLGP-----PVNVPQVSSMQMGAVDLLGGGLDSLLGSDLGGGIGGSPAVGQ 680
Query: 713 NGL--KIEFTFERSNT 726
+ + + TF S T
Sbjct: 681 SFIPSSVPATFAPSPT 696
>gi|14719400 ADP-ribosylation factor binding protein 3 isoform short
[Homo sapiens]
Length = 690
Score = 77.8 bits (190), Expect = 4e-14
Identities = 59/195 (30%), Positives = 93/195 (47%), Gaps = 23/195 (11%)
Query: 638 TPVIPTAPTSKP----SSAGGELLDLLGDINLTGAPAAAPAPASVPQISQPPFLLDGLSS 693
+P+IPT ++P S+ G L G+P P S+ I P + S+
Sbjct: 505 SPLIPTTTPARPLLPFSTGPGSPLFQPLSFQSQGSPPKGPE-LSLASIHVPLESIKPSSA 563
Query: 694 QPLFNDIAAGIPSITAYSKNGLKIEFTFERSNT--NPSVTVITIQASNSTELDMTDFVFQ 751
P +TAY KNG +I F F + P V V+ + N+ L + V Q
Sbjct: 564 LP-----------VTAYDKNGFRILFHFAKECPPGRPDVLVVVVSMLNTAPLPVKSIVLQ 612
Query: 752 AAVPKTFQLQLLSPSSSIVPAFNT----GTITQVIKVLNPQKQQLRMRIKLTYNHKGSAM 807
AAVPK+ +++L PS + + F+ ITQV+ + NP K+++R+R KLT+
Sbjct: 613 AAVPKSMKVKLQPPSGTELSPFSPIQPPAAITQVMLLANPLKEKVRLRYKLTFALGEQLS 672
Query: 808 QDLAEVNNFPP-QSW 821
++ EV+ FPP + W
Sbjct: 673 TEVGEVDQFPPVEQW 687
>gi|20336267 ADP-ribosylation factor binding protein 3 isoform long
[Homo sapiens]
Length = 723
Score = 77.8 bits (190), Expect = 4e-14
Identities = 59/195 (30%), Positives = 93/195 (47%), Gaps = 23/195 (11%)
Query: 638 TPVIPTAPTSKP----SSAGGELLDLLGDINLTGAPAAAPAPASVPQISQPPFLLDGLSS 693
+P+IPT ++P S+ G L G+P P S+ I P + S+
Sbjct: 538 SPLIPTTTPARPLLPFSTGPGSPLFQPLSFQSQGSPPKGPE-LSLASIHVPLESIKPSSA 596
Query: 694 QPLFNDIAAGIPSITAYSKNGLKIEFTFERSNT--NPSVTVITIQASNSTELDMTDFVFQ 751
P +TAY KNG +I F F + P V V+ + N+ L + V Q
Sbjct: 597 LP-----------VTAYDKNGFRILFHFAKECPPGRPDVLVVVVSMLNTAPLPVKSIVLQ 645
Query: 752 AAVPKTFQLQLLSPSSSIVPAFNT----GTITQVIKVLNPQKQQLRMRIKLTYNHKGSAM 807
AAVPK+ +++L PS + + F+ ITQV+ + NP K+++R+R KLT+
Sbjct: 646 AAVPKSMKVKLQPPSGTELSPFSPIQPPAAITQVMLLANPLKEKVRLRYKLTFALGEQLS 705
Query: 808 QDLAEVNNFPP-QSW 821
++ EV+ FPP + W
Sbjct: 706 TEVGEVDQFPPVEQW 720
>gi|4557469 adaptor-related protein complex 2, beta 1 subunit
isoform b [Homo sapiens]
Length = 937
Score = 76.3 bits (186), Expect = 1e-13
Identities = 158/783 (20%), Positives = 296/783 (37%), Gaps = 97/783 (12%)
Query: 82 KRIGYLGAMLLLDERQDVHLLMTNCIKNDLNHSTQFVQGLALCTLGCMGSSEMCRDLAGE 141
K++ YL M + D+ ++ N D ++ LA+ T+GC+ ++ L
Sbjct: 66 KKLVYLYLMNYAKSQPDMAIMAVNSFVKDCEDPNPLIRALAVRTMGCIRVDKITEYLCEP 125
Query: 142 VEKLLKTSNSYLRKKAALCA--VHVIRKVPELMEMFLPATKNLLNEKNHGVLHTSVVLLT 199
+ K LK + Y+RK AA+C +H I + FL + ++L+ + N V+ +V L+
Sbjct: 126 LRKCLKDEDPYVRKTAAVCVAKLHDINAQMVEDQGFLDSLRDLIADSNPMVVANAVAALS 185
Query: 200 EMCERSPDMLAHFRKLVPQLVRILKNLIMSGYSPEHDVSGISDPFLQVRILRLLRILGRN 259
E+ E P+ ++ L PQ + L + + Q+ IL L
Sbjct: 186 EISESHPN--SNLLDLNPQNINKLLTALNE-----------CTEWGQIFILDCLSNYNPK 232
Query: 260 DDDSSEAMNDILAQVATNTETSKNVGNAILYETVLTIMD----IKSESGLRVLAINILGR 315
DD ++++ + + T + +A++ V +M + +S + + L
Sbjct: 233 DDREAQSICERV------TPRLSHANSAVVLSAVKVLMKFLELLPKDSDYYNMLLKKLAP 286
Query: 316 ---FLLNNDKNIRYVALTSLLKTVQTDHNAVQRHRSTIVDCLKDLDVSIKRRAMELSFAL 372
LL+ + ++YVAL ++ VQ +++ D + +K +++ L
Sbjct: 287 PLVTLLSGEPEVQYVALRNINLIVQKRPEILKQEIKVFFVKYND-PIYVKLEKLDIMIRL 345
Query: 373 VNGNNIRGMMKELLYFLDSCEPEFKADCASGIFLAAEKYAPSKRWHIDTIMRVLTTAGSY 432
+ NI ++ EL + + +F I A K S + T++ ++ T +Y
Sbjct: 346 ASQANIAQVLAELKEYATEVDVDFVRKAVRAIGRCAIKVEQSAERCVSTLLDLIQTKVNY 405
Query: 433 VRDDAVPNLIQLITNSVEMHAYTVQRLYKAILGDYSQQPLVQVA-AWCIGEYGDLL---- 487
V +A+ + + + + L + + D +P + A W +GEY + +
Sbjct: 406 VVQEAIVVIRDIFRKYPNKYESIIATLCENL--DSLDEPDARAAMIWIVGEYAERIDNAD 463
Query: 488 ------VSGQCEEEEPIQVT------------EDEVLDILESVLI-----SNMSTSVTRG 524
+ G +E +Q+T E ++++ VL S+ RG
Sbjct: 464 ELLESFLEGFHDESTQVQLTLLTAIVKLFLKKPSETQELVQQVLSLATQDSDNPDLRDRG 523
Query: 525 YALTAIMKLS-TRFTCTVNRIKKVVSIYGSSIDVELQQRAV-EYNALFKKYDHMRSALLE 582
Y ++ V K ++S I+ L + +L Y +A +E
Sbjct: 524 YIYWRLLSTDPVTAKEVVLSEKPLISEETDLIEPTLLDELICHIGSLASVYHKPPNAFVE 583
Query: 583 --------RMPVMEKVTTNGPTEIVQTNGETEPAPLETKPPPSGPQPTSQANDLLDL-LG 633
+P+ T G + + G T LE P P DLL+L LG
Sbjct: 584 GSHGIHRKHLPIHHGSTDAGDSPV----GTTTATNLE--QPQVIPSQGDLLGDLLNLDLG 637
Query: 634 GNDITPVIPTAPTSKPSSAGGELLDLLGDINLTGAPAAAPAPASVPQISQPPF-----LL 688
P + + GG L L+G + + A AP+ P + L
Sbjct: 638 PPVNVPQVSSMQMGAVDLLGGGLDSLVGQSFIPSSVPATFAPSPTPAVVSSGLNDLFELS 697
Query: 689 DGLSSQPLFNDIAAGIPSITAYSKNGLKIEFTFERSNTNPSVTVITIQASNSTELDMTDF 748
G+ P +A + A GL+I TF + + + +N MTDF
Sbjct: 698 TGIGMAP-GGYVAPKAVWLPAVKAKGLEISGTFTHRQGH---IYMEMNFTNKALQHMTDF 753
Query: 749 VFQ------AAVPKTFQLQL---LSPSSSIVPAFNTGTITQVIKV--LNPQKQQLRMRIK 797
Q +P T L + L P+ SI + T+ V+K+ LN + ++ I
Sbjct: 754 AIQFNKNSFGVIPST-PLAIHTPLMPNQSIDVSLPLNTLGPVMKMEPLNNLQVAVKNNID 812
Query: 798 LTY 800
+ Y
Sbjct: 813 VFY 815
>gi|239758145 PREDICTED: similar to ADP-ribosylation factor binding
protein 2 [Homo sapiens]
Length = 134
Score = 75.5 bits (184), Expect = 2e-13
Identities = 39/120 (32%), Positives = 69/120 (57%), Gaps = 6/120 (5%)
Query: 704 IPSITAYSKNGLKIEFTFERSNT--NPSVTVITIQASNSTELDMTDFVFQAAVPKTFQLQ 761
+P + Y +NG +I F ++ +P V V+ + ++ + D +FQ AVPK+ +++
Sbjct: 7 LPPLIVYDRNGFRILLHFSQTGAPGHPEVQVLLLTMMSTAPQPVWDIMFQVAVPKSMRVK 66
Query: 762 LLSPSSSIVPAFNT----GTITQVIKVLNPQKQQLRMRIKLTYNHKGSAMQDLAEVNNFP 817
L SSS +PAF+ I+Q++ + NP K+ +R+R KLT+N G ++ EV +FP
Sbjct: 67 LQPASSSKLPAFSPLMPPAVISQMLLLDNPHKEPIRLRYKLTFNQGGQPFSEVGEVKDFP 126
>gi|109134349 coatomer protein complex, subunit gamma 2 [Homo
sapiens]
Length = 871
Score = 56.6 bits (135), Expect = 9e-08
Identities = 80/404 (19%), Positives = 161/404 (39%), Gaps = 45/404 (11%)
Query: 43 NTYRCRNV-AKLLYMHMLGYPAHFGQLECL-------KLIASQKFTDKRIGYLGAMLLLD 94
N RC ++ K+LY+ L HFG E +L S T +R+ YL +
Sbjct: 40 NPRRCLHILTKILYL--LNQGEHFGTTEATEAFFAMTRLFQSNDQTLRRMCYLTIKEMAT 97
Query: 95 ERQDVHLLMTNCIKNDLNHSTQFVQGLALCTLGCMGSSEMCRDLAGEVEKLLKTSNSYLR 154
+DV +++T+ + D+ +G A+ L + M + + +++ + S +
Sbjct: 98 ISEDV-IIVTSSLTKDMTGKEDVYRGPAIRALCRITDGTMLQAIERYMKQAIVDKVSSVS 156
Query: 155 KKAALCAVHVIRKVPELMEMFLPATKNLLNEKNHGVLHTSVVLLTEMCERSPDMLAHFRK 214
A + ++H +M++ K +NE ++++ +L H RK
Sbjct: 157 SSALVSSLH-------MMKISYDVVKRWINEAQEAASSDNIMVQYHAL----GVLYHLRK 205
Query: 215 LVPQLVRILKNLIMSGYSPEHDVSGISDPFLQVRILRLL-RILGRNDDDSSEAMNDILAQ 273
L +S + SG+ F ++R+ R+L +D + D +
Sbjct: 206 N--------DRLAVSKMLNKFTKSGLKSQFAYCMLIRIASRLLKETEDGHESPLFDFIES 257
Query: 274 VATNTETSKNVGNAILYETVLTIMDIKSESGLRVL-AINILGRFLLNNDKNIRYVALTSL 332
N ++YE I+ + + + + A+++L F + +RY A+ +L
Sbjct: 258 CLRNKH------EMVIYEAASAIIHLPNCTARELAPAVSVLQLFCSSPKPALRYAAVRTL 311
Query: 333 LKTVQTDHNAVQRHRSTIVDCLKDLDVSIKRRAMELSFALVNGNNIRGMMKELLYFLDSC 392
K +AV + + + D + SI A+ + +++ +MK++ F+
Sbjct: 312 NKVAMKHPSAVTACNLDLENLITDSNRSIATLAITTLLKTGSESSVDRLMKQISSFVSEI 371
Query: 393 EPEFKADCASGIFLAAEKYAPSKRWHIDTIMRVLTTAGSYVRDD 436
EFK I +KY P K ++M +T + +RDD
Sbjct: 372 SDEFKVVVVQAISALCQKY-PRKH----SVM--MTFLSNMLRDD 408
>gi|32484979 adaptor-related protein complex 3, beta 1 subunit [Homo
sapiens]
Length = 1094
Score = 53.9 bits (128), Expect = 6e-07
Identities = 90/451 (19%), Positives = 184/451 (40%), Gaps = 68/451 (15%)
Query: 71 LKLIASQKFTDKRIGYLGAMLLLDERQDVHLLMTNCIKNDLNHSTQFVQGLALCTLGCMG 130
+K +AS+ K++ Y+ + +E+QD+ LL + + L Q ++ AL L +
Sbjct: 84 VKNVASKNIEIKKLVYVYLVRYAEEQQDLALLSISTFQRALKDPNQLIRASALRVLSSIR 143
Query: 131 SSEMCRDLAGEVEKLLKTSNSYLRKKAALCAVHVIRKV----PELMEMFLPATKNLLNEK 186
+ + +++ + Y+RK AA H I+K+ PE EM + + LL +K
Sbjct: 144 VPIIVPIMMLAIKEASADLSPYVRKNAA----HAIQKLYSLDPEQKEMLIEVIEKLLKDK 199
Query: 187 NHGVLHTSVVLLTEMCERSPDML-AHFRKL---------------VPQLVRILKNLIMSG 230
+ V + V+ E+C D++ ++RKL + L R + +S
Sbjct: 200 STLVAGSVVMAFEEVCPDRIDLIHKNYRKLCNLLVDVEEWGQVVIIHMLTRYARTQFVSP 259
Query: 231 YSPEHDVSGISDPFLQVRILRLLRILGRNDDDSSE---------AMNDILAQVATNTETS 281
+ ++ F + +DDD E M+ + NT+
Sbjct: 260 WKEGDELEDNGKNFYE------------SDDDQKEKTDKKKKPYTMDPDHRLLIRNTKPL 307
Query: 282 KNVGNAILYETVLTI---MDIKSESGLRVLAINILGRFLLNNDKNIRYVALTSLLKTVQT 338
NA + V + + KSE+G +++ +++ LL +++ ++Y+ L ++
Sbjct: 308 LQSRNAAVVMAVAQLYWHISPKSEAG--IISKSLVR--LLRSNREVQYIVLQNIATM--- 360
Query: 339 DHNAVQRHRSTIVDCLKDLDV------SIKRRAMELSFALVNGNNIRGMMKELLYFLDSC 392
++QR + LK V IK +E+ L N NI +++E ++ S
Sbjct: 361 ---SIQR-KGMFEPYLKSFYVRSTDPTMIKTLKLEILTNLANEANISTLLREFQTYVKSQ 416
Query: 393 EPEFKADCASGIFLAAEKYAPSKRWHIDTIMRVLTTAGSYVRDDAVPNLIQLITNSVEMH 452
+ +F A I A ++ ++ +L+ V ++V + +L+ H
Sbjct: 417 DKQFAAATIQTIGRCATNILEVTDTCLNGLVCLLSNRDEIVVAESVVVIKKLLQMQPAQH 476
Query: 453 AYTVQRLYKAILGDYSQQPLVQVA-AWCIGE 482
++ + K + D P+ + + W IGE
Sbjct: 477 GEIIKHMAKLL--DSITVPVARASILWLIGE 505
>gi|221316632 coatomer protein complex, subunit beta 1 [Homo
sapiens]
Length = 953
Score = 53.9 bits (128), Expect = 6e-07
Identities = 88/474 (18%), Positives = 191/474 (40%), Gaps = 73/474 (15%)
Query: 101 LLMTNCIKNDLNHSTQFVQGLALCTLGCMGSSEMCRDLAGEVEKLLKTSNSYLRKKAALC 160
+L+ + + DL H +F++G L L + +E+ L + L+ +SY+R+ A L
Sbjct: 99 ILVCDAYRKDLQHPNEFIRGSTLRFLCKLKEAELLEPLMPAIRACLEHRHSYVRRNAVLA 158
Query: 161 AV-------HVIRKVPELMEMFLPATKNLLNEKNHGVLHTSVVLLTEMCERSPDMLAHFR 213
H+I PEL+ F L+NEK+ C+R+ M+
Sbjct: 159 IYTIYRNFEHLIPDAPELIHDF------LVNEKD------------ASCKRNAFMM---- 196
Query: 214 KLVPQLVRILKNLIMSGYSPEHDVSGISDPFLQVRILRLL-RILGRNDDDSSEAMNDILA 272
L+ ++ + S D LQ+ I+ L+ ++ N + + + I
Sbjct: 197 -----LIHADQDRALDYLSTCIDQVQTFGDILQLVIVELIYKVCHANPSERARFIRCIYN 251
Query: 273 QVATNTETSKNVGNAILYETVLTIMDIKS-ESGLRVLAINILGRFLLNNDKNIRYVALTS 331
+ +++ A+ YE T++ + S + ++ A + + +D N++ + L
Sbjct: 252 LLQSSSP-------AVKYEAAGTLVTLSSAPTAIKAAAQCYIDLIIKESDNNVKLIVLDR 304
Query: 332 LLKTVQTDHNAVQR-HRSTIVDCLKDL---DVSIKRRAMELSFALVNGNNIRGMM----K 383
L++ +H A +R + ++D L+ L D+ ++++ ++L+ LV+ N+ ++ K
Sbjct: 305 LIEL--KEHPAHERVLQDLVMDILRVLSTPDLEVRKKTLQLALDLVSSRNVEELVIVLKK 362
Query: 384 ELLYFLDSCEPE----FKADCASGIFLAAEKYAPSKRWHIDTIMRVLTTAGSYVRDDAVP 439
E++ + E E ++ + + ++ I +M L+ D +
Sbjct: 363 EVIKTNNVSEHEDTDKYRQLLVRTLHSCSVRFPDMAANVIPVLMEFLSDNNEAAAADVLE 422
Query: 440 NLIQLITNSVEMHAYTVQRLYKAILGDYSQQPLVQVAAWCIGEYGDLLVSGQCEEEEPIQ 499
+ + I + V+++ + + + + A W +GEY C +E IQ
Sbjct: 423 FVREAIQRFDNLRMLIVEKMLE-VFHAIKSVKIYRGALWILGEY--------CSTKEDIQ 473
Query: 500 VTEDEVLDILESVLISNMSTSVTRGYALTAIMKLSTRFTCTVNRIKKVVSIYGS 553
E+ L + I G +L TV ++K+V+ G+
Sbjct: 474 SVMTEIRRSLGEIPIVESEIKKEAG-------ELKPEEEITVGPVQKLVTEMGT 520
>gi|221316630 coatomer protein complex, subunit beta 1 [Homo
sapiens]
Length = 953
Score = 53.9 bits (128), Expect = 6e-07
Identities = 88/474 (18%), Positives = 191/474 (40%), Gaps = 73/474 (15%)
Query: 101 LLMTNCIKNDLNHSTQFVQGLALCTLGCMGSSEMCRDLAGEVEKLLKTSNSYLRKKAALC 160
+L+ + + DL H +F++G L L + +E+ L + L+ +SY+R+ A L
Sbjct: 99 ILVCDAYRKDLQHPNEFIRGSTLRFLCKLKEAELLEPLMPAIRACLEHRHSYVRRNAVLA 158
Query: 161 AV-------HVIRKVPELMEMFLPATKNLLNEKNHGVLHTSVVLLTEMCERSPDMLAHFR 213
H+I PEL+ F L+NEK+ C+R+ M+
Sbjct: 159 IYTIYRNFEHLIPDAPELIHDF------LVNEKD------------ASCKRNAFMM---- 196
Query: 214 KLVPQLVRILKNLIMSGYSPEHDVSGISDPFLQVRILRLL-RILGRNDDDSSEAMNDILA 272
L+ ++ + S D LQ+ I+ L+ ++ N + + + I
Sbjct: 197 -----LIHADQDRALDYLSTCIDQVQTFGDILQLVIVELIYKVCHANPSERARFIRCIYN 251
Query: 273 QVATNTETSKNVGNAILYETVLTIMDIKS-ESGLRVLAINILGRFLLNNDKNIRYVALTS 331
+ +++ A+ YE T++ + S + ++ A + + +D N++ + L
Sbjct: 252 LLQSSSP-------AVKYEAAGTLVTLSSAPTAIKAAAQCYIDLIIKESDNNVKLIVLDR 304
Query: 332 LLKTVQTDHNAVQR-HRSTIVDCLKDL---DVSIKRRAMELSFALVNGNNIRGMM----K 383
L++ +H A +R + ++D L+ L D+ ++++ ++L+ LV+ N+ ++ K
Sbjct: 305 LIEL--KEHPAHERVLQDLVMDILRVLSTPDLEVRKKTLQLALDLVSSRNVEELVIVLKK 362
Query: 384 ELLYFLDSCEPE----FKADCASGIFLAAEKYAPSKRWHIDTIMRVLTTAGSYVRDDAVP 439
E++ + E E ++ + + ++ I +M L+ D +
Sbjct: 363 EVIKTNNVSEHEDTDKYRQLLVRTLHSCSVRFPDMAANVIPVLMEFLSDNNEAAAADVLE 422
Query: 440 NLIQLITNSVEMHAYTVQRLYKAILGDYSQQPLVQVAAWCIGEYGDLLVSGQCEEEEPIQ 499
+ + I + V+++ + + + + A W +GEY C +E IQ
Sbjct: 423 FVREAIQRFDNLRMLIVEKMLE-VFHAIKSVKIYRGALWILGEY--------CSTKEDIQ 473
Query: 500 VTEDEVLDILESVLISNMSTSVTRGYALTAIMKLSTRFTCTVNRIKKVVSIYGS 553
E+ L + I G +L TV ++K+V+ G+
Sbjct: 474 SVMTEIRRSLGEIPIVESEIKKEAG-------ELKPEEEITVGPVQKLVTEMGT 520
>gi|7705369 coatomer protein complex, subunit beta 1 [Homo sapiens]
Length = 953
Score = 53.9 bits (128), Expect = 6e-07
Identities = 88/474 (18%), Positives = 191/474 (40%), Gaps = 73/474 (15%)
Query: 101 LLMTNCIKNDLNHSTQFVQGLALCTLGCMGSSEMCRDLAGEVEKLLKTSNSYLRKKAALC 160
+L+ + + DL H +F++G L L + +E+ L + L+ +SY+R+ A L
Sbjct: 99 ILVCDAYRKDLQHPNEFIRGSTLRFLCKLKEAELLEPLMPAIRACLEHRHSYVRRNAVLA 158
Query: 161 AV-------HVIRKVPELMEMFLPATKNLLNEKNHGVLHTSVVLLTEMCERSPDMLAHFR 213
H+I PEL+ F L+NEK+ C+R+ M+
Sbjct: 159 IYTIYRNFEHLIPDAPELIHDF------LVNEKD------------ASCKRNAFMM---- 196
Query: 214 KLVPQLVRILKNLIMSGYSPEHDVSGISDPFLQVRILRLL-RILGRNDDDSSEAMNDILA 272
L+ ++ + S D LQ+ I+ L+ ++ N + + + I
Sbjct: 197 -----LIHADQDRALDYLSTCIDQVQTFGDILQLVIVELIYKVCHANPSERARFIRCIYN 251
Query: 273 QVATNTETSKNVGNAILYETVLTIMDIKS-ESGLRVLAINILGRFLLNNDKNIRYVALTS 331
+ +++ A+ YE T++ + S + ++ A + + +D N++ + L
Sbjct: 252 LLQSSSP-------AVKYEAAGTLVTLSSAPTAIKAAAQCYIDLIIKESDNNVKLIVLDR 304
Query: 332 LLKTVQTDHNAVQR-HRSTIVDCLKDL---DVSIKRRAMELSFALVNGNNIRGMM----K 383
L++ +H A +R + ++D L+ L D+ ++++ ++L+ LV+ N+ ++ K
Sbjct: 305 LIEL--KEHPAHERVLQDLVMDILRVLSTPDLEVRKKTLQLALDLVSSRNVEELVIVLKK 362
Query: 384 ELLYFLDSCEPE----FKADCASGIFLAAEKYAPSKRWHIDTIMRVLTTAGSYVRDDAVP 439
E++ + E E ++ + + ++ I +M L+ D +
Sbjct: 363 EVIKTNNVSEHEDTDKYRQLLVRTLHSCSVRFPDMAANVIPVLMEFLSDNNEAAAADVLE 422
Query: 440 NLIQLITNSVEMHAYTVQRLYKAILGDYSQQPLVQVAAWCIGEYGDLLVSGQCEEEEPIQ 499
+ + I + V+++ + + + + A W +GEY C +E IQ
Sbjct: 423 FVREAIQRFDNLRMLIVEKMLE-VFHAIKSVKIYRGALWILGEY--------CSTKEDIQ 473
Query: 500 VTEDEVLDILESVLISNMSTSVTRGYALTAIMKLSTRFTCTVNRIKKVVSIYGS 553
E+ L + I G +L TV ++K+V+ G+
Sbjct: 474 SVMTEIRRSLGEIPIVESEIKKEAG-------ELKPEEEITVGPVQKLVTEMGT 520
>gi|11559929 coatomer protein complex, subunit gamma 1 [Homo
sapiens]
Length = 874
Score = 52.0 bits (123), Expect = 2e-06
Identities = 77/410 (18%), Positives = 165/410 (40%), Gaps = 38/410 (9%)
Query: 43 NTYRCRNV-AKLLYMHMLGYPAHFGQLECL-------KLIASQKFTDKRIGYLGAMLLLD 94
N +C ++ K+LY+ G H G E KL S T +R+ YL +
Sbjct: 40 NPRKCAHILTKILYLINQG--EHLGTTEATEAFFAMTKLFQSNDPTLRRMCYLTIKEMSC 97
Query: 95 ERQDVHLLMTNCIKNDLNHSTQFVQGLALCTLGCMGSSEMCRDLAGEVEKLLKTSNSYLR 154
+DV +++T+ + D+ +G A+ L + S M + + +++ + +
Sbjct: 98 IAEDV-IIVTSSLTKDMTGKEDNYRGPAVRALCQITDSTMLQAIERYMKQAIVDKVPSVS 156
Query: 155 KKAALCAVHVIRKVPELMEMFLPATKNLLNEKNHGVLHTSVVLLTEMCERSPDMLAHFRK 214
A + ++H+++ ++++ ++ + + N V + ++ LL + R D LA K
Sbjct: 157 SSALVSSLHLLKCSFDVVKRWVNEAQEAASSDNIMVQYHALGLLYHV--RKNDRLA-VNK 213
Query: 215 LVPQLVRILKNLIMSGYSPEHDVSGISDPFLQVRILRLL-RILGRNDDDSSEAMNDILAQ 273
++ ++ R G+ PF ++R+ + L D + D +
Sbjct: 214 MISKVTR----------------HGLKSPFAYCMMIRVASKQLEEEDGSRDSPLFDFIES 257
Query: 274 VATNTETSKNVGNAILYETVLTIMDIKSESGLRVL-AINILGRFLLNNDKNIRYVALTSL 332
N ++YE I+++ S + A+++L F + +RY A+ +L
Sbjct: 258 CLRNKH------EMVVYEAASAIVNLPGCSAKELAPAVSVLQLFCSSPKAALRYAAVRTL 311
Query: 333 LKTVQTDHNAVQRHRSTIVDCLKDLDVSIKRRAMELSFALVNGNNIRGMMKELLYFLDSC 392
K +AV + + + D + SI A+ + ++I +MK++ F+
Sbjct: 312 NKVAMKHPSAVTACNLDLENLVTDSNRSIATLAITTLLKTGSESSIDRLMKQISSFMSEI 371
Query: 393 EPEFKADCASGIFLAAEKYAPSKRWHIDTIMRVLTTAGSYVRDDAVPNLI 442
EFK I +KY ++ + +L G + A+ + I
Sbjct: 372 SDEFKVVVVQAISALCQKYPRKHAVLMNFLFTMLREEGGFEYKRAIVDCI 421
>gi|166197671 adaptor-related protein complex 4, beta 1 subunit
[Homo sapiens]
Length = 739
Score = 41.2 bits (95), Expect = 0.004
Identities = 92/480 (19%), Positives = 194/480 (40%), Gaps = 39/480 (8%)
Query: 46 RCRNVAKLLYMHML-GYPAHFGQLECLKLIASQKFTDKRIGYLGAMLLLDERQDVHLLMT 104
R RNV + + +M G +E +K A+ K++ YL + D+ LL
Sbjct: 28 RYRNVIQRVIRYMTQGLDMSGVFMEMVKASATVDIVQKKLVYLYMCTYAPLKPDLALLAI 87
Query: 105 NCIKNDLNHSTQFVQGLAL---CTLGCMGSSEMCRDLAGEVEKLLKTSNSYLRKKAAL-C 160
N + D + V+GLAL C+L G E + + L+ SY+R+ A L C
Sbjct: 88 NTLCKDCSDPNPMVRGLALRSMCSLRMPGVQEYIQQ---PILNGLRDKASYVRRVAVLGC 144
Query: 161 A-VHVIRKVPELMEMFLPATKNLLNEKNHGVLHTSVVLLTEMCERSPDMLAHFRKLVPQL 219
A +H + E+ + +LL +++ V+ + L E+ ++ ++ + + + L
Sbjct: 145 AKMHNLHGDSEVDGALVNELYSLLRDQDPIVVVNCLRSLEEILKQEGGVVIN-KPIAHHL 203
Query: 220 VRILKNLIMSGYSPEHDVSGISDPFLQVRILR-LLRILGRNDDDSSEAMNDILAQVATNT 278
+ + L D + Q +L LLR R++++ + +N +L ++
Sbjct: 204 LNRMSKL---------------DQWGQAEVLNFLLRYQPRSEEELFDILN-LLDSFLKSS 247
Query: 279 ETSKNVGNAILYETVLTIMDIKSESGLRVLAINILGRFLLNNDKNIRYVALTSLLKTVQT 338
+G L+ +L M ++ + V L + + + +VAL + + + +
Sbjct: 248 SPGVVMGATKLF-LILAKMFPHVQTDVLVRVKGPLLAACSSESRELCFVALCHVRQILHS 306
Query: 339 DHNAVQRHRSTIVDCLKDLDVSIKRRAMELSFALVNGNNIRGMMKELLYFLDSCEPEFKA 398
H C IK + +E+ LVN N++ +++EL + + A
Sbjct: 307 LPGHFSSHYKKFF-CSYSEPHYIKLQKVEVLCELVNDENVQQVLEELRGYC----TDVSA 361
Query: 399 DCASGIFLAAEKYAPSKRWHIDTIMRVLTTAGSYVRDDAVPNLIQLITNSVEMHAYTVQR 458
D A A A R + D +++LT ++ ++Q + V + +
Sbjct: 362 DFAQAAIFAIGGIA---RTYTDQCVQILTELLGLRQEHITTVVVQTFRDLVWLCPQCTEA 418
Query: 459 LYKAILG---DYSQQPLVQVAAWCIGEYGDLLVSGQCEEEEPIQVTEDEVLDILESVLIS 515
+ +A+ G + Q W +G +G+ + + E+ ++ + E ++ L++
Sbjct: 419 VCQALPGCEENIQDSEGKQALIWLLGVHGERIPNAPYVLEDFVENVKSETFPAVKMELLT 478
>gi|31324577 molecule interacting with Rab13 [Homo sapiens]
Length = 863
Score = 39.7 bits (91), Expect = 0.011
Identities = 39/166 (23%), Positives = 74/166 (44%), Gaps = 9/166 (5%)
Query: 598 IVQTNGETEPAPLETKPPPSGPQPTSQANDLLDLLGGNDITPVIPTAPTSKPSSAGGELL 657
+VQ + +PAPL PP S P P SQ + ++ G ++ PTA E
Sbjct: 374 LVQAEPKKKPAPL---PPSSSPGPPSQDSRQVENGGTEEVAQPSPTASLESKPYNPFEEE 430
Query: 658 DLLGDINLTGAPAAAPAPA-----SVPQISQPPFLLDGLSSQPLFNDIAAGIPSITAYSK 712
+ + AP+ A +PA S P+ P + + SS A PS + +
Sbjct: 431 EEDKEEEAPAAPSLATSPALGHPESTPKSLHPWYGITPTSSPKTKKRPAPRAPSASPLAL 490
Query: 713 NGLKIEFTFERSNT-NPSVTVITIQASNSTELDMTDFVFQAAVPKT 757
+ ++ + S T +P+++V ++ + ++++ + + AVPK+
Sbjct: 491 HASRLSHSEPPSATPSPALSVESLSSESASQTAGAELLEPPAVPKS 536
>gi|241982780 programmed cell death 6 interacting protein isoform 2
[Homo sapiens]
Length = 873
Score = 37.7 bits (86), Expect = 0.044
Identities = 41/182 (22%), Positives = 69/182 (37%), Gaps = 38/182 (20%)
Query: 509 LESVLISNMSTSVTRGYALTAIMKLSTRFTCTVNRIKKVVSIYGSSIDVELQQRAVEYNA 568
L ++ N++T+ L A +K T+F N + +++ + + + R E +
Sbjct: 653 LREEVLKNLATAYDNFVELVANLKEGTKF---YNELTEILVRFQNKCSDIVFARKTERDE 709
Query: 569 LFKKYDHMRSALLERMPVMEKVTTNGPTEIVQTN-----GETEPAPLETKPPPSGPQPTS 623
L K L++ E + PT Q++ T P P PP+ PQP +
Sbjct: 710 LLKD--------LQQSIAREPSAPSIPTPAYQSSPAGGHAPTPPTPAPRTMPPTKPQPPA 761
Query: 624 QANDLLDLLGGNDITPVIPTAPTSKPSSAGGELLDLLGDINLTGAPAAAPAPASVPQISQ 683
+ P P P ++ SA + GA AAPAP+ P +
Sbjct: 762 R--------------PPPPVLPANRAPSATAP--------SPVGAGTAAPAPSQTPGSAP 799
Query: 684 PP 685
PP
Sbjct: 800 PP 801
>gi|22027538 programmed cell death 6 interacting protein isoform 1
[Homo sapiens]
Length = 868
Score = 37.7 bits (86), Expect = 0.044
Identities = 41/182 (22%), Positives = 69/182 (37%), Gaps = 38/182 (20%)
Query: 509 LESVLISNMSTSVTRGYALTAIMKLSTRFTCTVNRIKKVVSIYGSSIDVELQQRAVEYNA 568
L ++ N++T+ L A +K T+F N + +++ + + + R E +
Sbjct: 648 LREEVLKNLATAYDNFVELVANLKEGTKF---YNELTEILVRFQNKCSDIVFARKTERDE 704
Query: 569 LFKKYDHMRSALLERMPVMEKVTTNGPTEIVQTN-----GETEPAPLETKPPPSGPQPTS 623
L K L++ E + PT Q++ T P P PP+ PQP +
Sbjct: 705 LLKD--------LQQSIAREPSAPSIPTPAYQSSPAGGHAPTPPTPAPRTMPPTKPQPPA 756
Query: 624 QANDLLDLLGGNDITPVIPTAPTSKPSSAGGELLDLLGDINLTGAPAAAPAPASVPQISQ 683
+ P P P ++ SA + GA AAPAP+ P +
Sbjct: 757 R--------------PPPPVLPANRAPSATAP--------SPVGAGTAAPAPSQTPGSAP 794
Query: 684 PP 685
PP
Sbjct: 795 PP 796
>gi|153792780 additional sex combs like 2 [Homo sapiens]
Length = 1435
Score = 37.7 bits (86), Expect = 0.044
Identities = 64/232 (27%), Positives = 88/232 (37%), Gaps = 26/232 (11%)
Query: 585 PVMEKVTTN---GPTEIVQTNGETEPAPLETKPPPSGPQPTSQANDLLDLLGGNDITPVI 641
P +E T G E++ ET+P ETK PS QP S + L TP +
Sbjct: 727 PTLELAGTGSRGGTRELLPCGPETQPQS-ETKTTPSQAQPHSVSGAQLQQTPPVPPTPAV 785
Query: 642 PTAPTSKPSSAGGELLDLLGDINLTGAPAAAPA------PASVPQISQP----PFLLDGL 691
A TS PS A E LD +N T A A + P+S Q P P L+ G
Sbjct: 786 SGACTSVPSPAHIEKLD-NEKLNPTRATATVASVSHPQGPSSCRQEKAPSPTGPALISGA 844
Query: 692 SSQPLFND----IAAG----IPSITAYSKNGLKIEFTFERSNTNPSVTVITIQASNSTEL 743
S D + AG IP+ +A SK + S +T T++ ++
Sbjct: 845 SPVHCAADGTVELKAGPSKNIPNPSASSKTDASVPVAVTPSPLTSLLTTATLEKLPVPQV 904
Query: 744 DMTDFVFQAAVPKT---FQLQLLSPSSSIVPAFNTGTITQVIKVLNPQKQQL 792
T +A P + L +P +S+ T T I NP QL
Sbjct: 905 SATTAPAGSAPPSSTLPAASSLKTPGTSLNMNGPTLRPTSSIPANNPLVTQL 956
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.319 0.133 0.379
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 29,399,106
Number of Sequences: 37866
Number of extensions: 1375388
Number of successful extensions: 6218
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 30
Number of HSP's successfully gapped in prelim test: 131
Number of HSP's that attempted gapping in prelim test: 5855
Number of HSP's gapped (non-prelim): 414
length of query: 822
length of database: 18,247,518
effective HSP length: 111
effective length of query: 711
effective length of database: 14,044,392
effective search space: 9985562712
effective search space used: 9985562712
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.