Search of human proteins with 71284432

Search of human proteins with 71284432

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|71284432 WD repeat domain 40B [Homo sapiens]
         (463 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|71284432 WD repeat domain 40B [Homo sapiens]                       954   0.0  
gi|61966713 DDB1 and CUL4 associated factor 12-like 2 [Homo sapi...   829   0.0  
gi|22218619 WD repeat domain 40A [Homo sapiens]                       555   e-158
gi|21536371 telomerase-associated protein 1 [Homo sapiens]             40   0.004
gi|21071067 TBP-associated factor 5 [Homo sapiens]                     37   0.029
gi|55743149 WD repeat domain 17 isoform 2 [Homo sapiens]               37   0.029
gi|31317311 WD repeat domain 17 isoform 1 [Homo sapiens]               37   0.029
gi|118402582 cell division cycle 20 [Homo sapiens]                     37   0.038
gi|19913371 transducin (beta)-like 1 X-linked receptor 1 [Homo s...    37   0.038
gi|19913369 transducin beta-like 3 [Homo sapiens]                      37   0.038
gi|11055998 guanine nucleotide-binding protein, beta-4 subunit [...    37   0.049
gi|48928050 F-box and WD repeat domain containing 11 isoform C [...    36   0.065
gi|213021190 transducin beta-like 1X isoform b [Homo sapiens]          36   0.065
gi|213021188 transducin beta-like 1X isoform b [Homo sapiens]          36   0.065
gi|213021186 transducin beta-like 1X isoform a [Homo sapiens]          36   0.065
gi|5032159 transducin beta-like 1X isoform a [Homo sapiens]            36   0.065
gi|48928048 F-box and WD repeat domain containing 11 isoform A [...    36   0.065
gi|48928046 F-box and WD repeat domain containing 11 isoform B [...    36   0.065
gi|19913367 transducin beta-like 1Y [Homo sapiens]                     36   0.084
gi|19913365 transducin beta-like 1Y [Homo sapiens]                     36   0.084
gi|15150805 transducin beta-like 1Y [Homo sapiens]                     36   0.084
gi|11321585 guanine nucleotide-binding protein, beta-1 subunit [...    35   0.11 
gi|38569484 kinesin family member 21A [Homo sapiens]                   35   0.11 
gi|17402902 guanine nucleotide binding protein beta-subunit-like...    35   0.11 
gi|153791630 bromodomain and WD repeat domain containing 3 [Homo...    35   0.11 
gi|20357529 guanine nucleotide-binding protein, beta-2 subunit [...    35   0.14 
gi|4505895 pleiotropic regulator 1 (PRL1 homolog, Arabidopsis) [...    33   0.42 
gi|4759276 RNA, U3 small nucleolar interacting protein 2 [Homo s...    33   0.55 
gi|53729352 WD repeat-containing protein 1 isoform 2 [Homo sapiens]    33   0.55 
gi|9257257 WD repeat-containing protein 1 isoform 1 [Homo sapiens]     33   0.55 

>gi|71284432 WD repeat domain 40B [Homo sapiens]
          Length = 463

 Score =  954 bits (2465), Expect = 0.0
 Identities = 463/463 (100%), Positives = 463/463 (100%)

Query: 1   MAQQQTGSRKRKAPAVEADAESSPSQGLAAADGEGPLLLKRQRRPATYRSMAHYLKVREV 60
           MAQQQTGSRKRKAPAVEADAESSPSQGLAAADGEGPLLLKRQRRPATYRSMAHYLKVREV
Sbjct: 1   MAQQQTGSRKRKAPAVEADAESSPSQGLAAADGEGPLLLKRQRRPATYRSMAHYLKVREV 60

Query: 61  GGWGPARLQGFDGELRGYAVQRLPELLTERQLELGTVNKVFASQWLNSRQVVCGTKCNTL 120
           GGWGPARLQGFDGELRGYAVQRLPELLTERQLELGTVNKVFASQWLNSRQVVCGTKCNTL
Sbjct: 61  GGWGPARLQGFDGELRGYAVQRLPELLTERQLELGTVNKVFASQWLNSRQVVCGTKCNTL 120

Query: 121 FVVDVESGHIARIPLLRDSEARLAQDQQGCGIHAIELNPSKTLLATGGENPNSLAIYQLP 180
           FVVDVESGHIARIPLLRDSEARLAQDQQGCGIHAIELNPSKTLLATGGENPNSLAIYQLP
Sbjct: 121 FVVDVESGHIARIPLLRDSEARLAQDQQGCGIHAIELNPSKTLLATGGENPNSLAIYQLP 180

Query: 181 SLDPLCLGDRHGHKDWIFAVAWLSDTVAVSGSRDGTVALWRMDPDKFDDTVAWHSEVGLP 240
           SLDPLCLGDRHGHKDWIFAVAWLSDTVAVSGSRDGTVALWRMDPDKFDDTVAWHSEVGLP
Sbjct: 181 SLDPLCLGDRHGHKDWIFAVAWLSDTVAVSGSRDGTVALWRMDPDKFDDTVAWHSEVGLP 240

Query: 241 VYAHIRPRDVEAIPRAIINPSNRKVRALACGGKNQELGAVSLDGYFHLWKAGSALSRLLS 300
           VYAHIRPRDVEAIPRAIINPSNRKVRALACGGKNQELGAVSLDGYFHLWKAGSALSRLLS
Sbjct: 241 VYAHIRPRDVEAIPRAIINPSNRKVRALACGGKNQELGAVSLDGYFHLWKAGSALSRLLS 300

Query: 301 IRLPYFRDNVCLTYCDDMSVYAVGSHSHVSFLDLRQDQQNIRPLCSREGGTGVRSLSFYR 360
           IRLPYFRDNVCLTYCDDMSVYAVGSHSHVSFLDLRQDQQNIRPLCSREGGTGVRSLSFYR
Sbjct: 301 IRLPYFRDNVCLTYCDDMSVYAVGSHSHVSFLDLRQDQQNIRPLCSREGGTGVRSLSFYR 360

Query: 361 HIITVGTGQGSLLFYDVRAQKFLEERASATLESSSGPARRKLRLACGRGWLNHNDFWVNY 420
           HIITVGTGQGSLLFYDVRAQKFLEERASATLESSSGPARRKLRLACGRGWLNHNDFWVNY
Sbjct: 361 HIITVGTGQGSLLFYDVRAQKFLEERASATLESSSGPARRKLRLACGRGWLNHNDFWVNY 420

Query: 421 FGGMEVFPNALYTHCYNWPEMKLFVAGGPLPAGLHGNYAGLWS 463
           FGGMEVFPNALYTHCYNWPEMKLFVAGGPLPAGLHGNYAGLWS
Sbjct: 421 FGGMEVFPNALYTHCYNWPEMKLFVAGGPLPAGLHGNYAGLWS 463


>gi|61966713 DDB1 and CUL4 associated factor 12-like 2 [Homo
           sapiens]
          Length = 463

 Score =  829 bits (2142), Expect = 0.0
 Identities = 402/463 (86%), Positives = 427/463 (92%)

Query: 1   MAQQQTGSRKRKAPAVEADAESSPSQGLAAADGEGPLLLKRQRRPATYRSMAHYLKVREV 60
           MAQQQTGSRKRKAPAVEA A SS SQGLAAADGEGPLL K+Q+RPAT R + HYLK REV
Sbjct: 1   MAQQQTGSRKRKAPAVEAGAGSSSSQGLAAADGEGPLLPKKQKRPATRRRLVHYLKGREV 60

Query: 61  GGWGPARLQGFDGELRGYAVQRLPELLTERQLELGTVNKVFASQWLNSRQVVCGTKCNTL 120
           G  GPA LQGF+GELRGYAVQRLPELLTERQL+LGT+NKVFASQWLN+RQVVCGTKCNTL
Sbjct: 61  GARGPAGLQGFEGELRGYAVQRLPELLTERQLDLGTLNKVFASQWLNARQVVCGTKCNTL 120

Query: 121 FVVDVESGHIARIPLLRDSEARLAQDQQGCGIHAIELNPSKTLLATGGENPNSLAIYQLP 180
           FVVDV+SGHI RIPL+RD EA LAQ  QGCGIHAIELNPSKTLLATGGENPNSLAIYQLP
Sbjct: 121 FVVDVQSGHITRIPLMRDKEAGLAQAHQGCGIHAIELNPSKTLLATGGENPNSLAIYQLP 180

Query: 181 SLDPLCLGDRHGHKDWIFAVAWLSDTVAVSGSRDGTVALWRMDPDKFDDTVAWHSEVGLP 240
           +LDPLCLGDRHGHKDWIFAVAWLSDTVAVSGSRDGTVALWRMDPD F+ ++AWHSEVGLP
Sbjct: 181 TLDPLCLGDRHGHKDWIFAVAWLSDTVAVSGSRDGTVALWRMDPDMFNGSIAWHSEVGLP 240

Query: 241 VYAHIRPRDVEAIPRAIINPSNRKVRALACGGKNQELGAVSLDGYFHLWKAGSALSRLLS 300
           VYAHIRPRDVEAIPRA  NPSNRKVRALA  GKNQELGAVSLDGYFHLWKA S LSRLLS
Sbjct: 241 VYAHIRPRDVEAIPRASTNPSNRKVRALAFSGKNQELGAVSLDGYFHLWKARSTLSRLLS 300

Query: 301 IRLPYFRDNVCLTYCDDMSVYAVGSHSHVSFLDLRQDQQNIRPLCSREGGTGVRSLSFYR 360
           IRLPY R+NVCLTYCD++S+YAVGS SHVSFLD RQ QQNIRPLCSREGGTGVRSLSFY+
Sbjct: 301 IRLPYCRENVCLTYCDELSLYAVGSQSHVSFLDPRQRQQNIRPLCSREGGTGVRSLSFYQ 360

Query: 361 HIITVGTGQGSLLFYDVRAQKFLEERASATLESSSGPARRKLRLACGRGWLNHNDFWVNY 420
           HIITVGTG GSLLFYD+RAQKFLEERAS++L+S  GPA RKL+LACGRGWLN +D WVNY
Sbjct: 361 HIITVGTGHGSLLFYDIRAQKFLEERASSSLDSMPGPAGRKLKLACGRGWLNQDDVWVNY 420

Query: 421 FGGMEVFPNALYTHCYNWPEMKLFVAGGPLPAGLHGNYAGLWS 463
           FGGM  FPNALYTHCYNWPEMKLFVAGGPLP+GLHGNYAGLWS
Sbjct: 421 FGGMGEFPNALYTHCYNWPEMKLFVAGGPLPSGLHGNYAGLWS 463


>gi|22218619 WD repeat domain 40A [Homo sapiens]
          Length = 453

 Score =  555 bits (1429), Expect = e-158
 Identities = 285/465 (61%), Positives = 343/465 (73%), Gaps = 27/465 (5%)

Query: 8   SRKRKAPAVEADAESSPSQGLAAADGEGPL------LLKRQRRPATYRSMAHYLKVREVG 61
           SRKRKAPA       SP  G   +D +GP       L KR+R P   RS+ +YLK REV 
Sbjct: 7   SRKRKAPA-------SPGAG---SDAQGPQFGWDHSLHKRKRLPPVKRSLVYYLKNREV- 55

Query: 62  GWGPARLQG---FDGELRGYAVQRLPELLTERQLELGTVNKVFASQWLNSRQVVCGTKCN 118
                RLQ    +   L GYA Q+LP LL ER+  LGT+NKVFASQWLN RQVVCGTKCN
Sbjct: 56  -----RLQNETSYSRVLHGYAAQQLPSLLKEREFHLGTLNKVFASQWLNHRQVVCGTKCN 110

Query: 119 TLFVVDVESGHIARIPLLRDSEARLAQDQQGCGIHAIELNPSKTLLATGGENPNSLAIYQ 178
           TLFVVDV++  I +IP+L+D E      QQGCGIHAIELNPS+TLLATGG+NPNSLAIY+
Sbjct: 111 TLFVVDVQTSQITKIPILKDREPG-GVTQQGCGIHAIELNPSRTLLATGGDNPNSLAIYR 169

Query: 179 LPSLDPLCLGDRHGHKDWIFAVAWLSDTVAVSGSRDGTVALWRMDPDKFDDTVAWHSEVG 238
           LP+LDP+C+GD  GHKDWIF++AW+SDT+AVSGSRDG++ LW +  D    + A H+   
Sbjct: 170 LPTLDPVCVGD-DGHKDWIFSIAWISDTMAVSGSRDGSMGLWEVTDDVLTKSDARHNVSR 228

Query: 239 LPVYAHIRPRDVEAIPRAIINPSNRKVRALACGGKNQELGAVSLDGYFHLWKAGSALSRL 298
           +PVYAHI  + ++ IP+   NP N KVRALA   KN+ELGAVSLDGYFHLWKA + LS+L
Sbjct: 229 VPVYAHITHKALKDIPKEDTNPDNCKVRALAFNNKNKELGAVSLDGYFHLWKAENTLSKL 288

Query: 299 LSIRLPYFRDNVCLTYCDDMSVYAVGSHSHVSFLDLRQDQQNIRPLCSREGGTGVRSLSF 358
           LS +LPY R+NVCL Y  + SVYAVGS +HVSFLD RQ   N++ +CSRE G+G+RS+SF
Sbjct: 289 LSTKLPYCRENVCLAYGSEWSVYAVGSQAHVSFLDPRQPSYNVKSVCSRERGSGIRSVSF 348

Query: 359 YRHIITVGTGQGSLLFYDVRAQKFLEERASATLESSSGPARRKLRLACGRGWLNHNDFWV 418
           Y HIITVGTGQGSLLFYD+RAQ+FLEER SA   S    A   L+L  G+GWLNH++ W 
Sbjct: 349 YEHIITVGTGQGSLLFYDIRAQRFLEERLSACYGSKPRLAGENLKLTTGKGWLNHDETWR 408

Query: 419 NYFGGMEVFPNALYTHCYNWPEMKLFVAGGPLPAGLHGNYAGLWS 463
           NYF  ++ FPNA+YTHCY+    KLFVAGGPLP+GLHGNYAGLWS
Sbjct: 409 NYFSDIDFFPNAVYTHCYDSSGTKLFVAGGPLPSGLHGNYAGLWS 453


>gi|21536371 telomerase-associated protein 1 [Homo sapiens]
          Length = 2627

 Score = 40.0 bits (92), Expect = 0.004
 Identities = 23/63 (36%), Positives = 32/63 (50%), Gaps = 3/63 (4%)

Query: 164  LATGGENPNSLAI-YQLPSLDPLCLGDRHGHKDWIFAVAWLSDTVAVSGSRDGTVALWRM 222
            LATGG + + L    + P    L       H+DW+   AW  D + +S S DG+V LW  
Sbjct: 2076 LATGGRDRSLLCWDVRTPKTPVLIHSFPACHRDWVTGCAWTKDNLLISCSSDGSVGLW-- 2133

Query: 223  DPD 225
            DP+
Sbjct: 2134 DPE 2136



 Score = 30.4 bits (67), Expect = 3.5
 Identities = 21/72 (29%), Positives = 39/72 (54%), Gaps = 6/72 (8%)

Query: 152  IHAIELNPSKTLLATGGENPNSLAIYQLPS-LDPLCLGDRHGHKDWIFAVAWLSD-TVAV 209
            + A  ++ +  L+ T  E+  S+ ++Q+P   D  C+         + AVAW  D ++AV
Sbjct: 2241 VRAAAVSETSGLMLTASED-GSVRLWQVPKEADDTCIPRSSAA---VTAVAWAPDGSMAV 2296

Query: 210  SGSRDGTVALWR 221
            SG++ G + LW+
Sbjct: 2297 SGNQAGELILWQ 2308



 Score = 30.0 bits (66), Expect = 4.6
 Identities = 12/26 (46%), Positives = 18/26 (69%)

Query: 197  IFAVAWLSDTVAVSGSRDGTVALWRM 222
            + A+AWLS  V VSG+ DG++  W +
Sbjct: 1972 VSALAWLSPKVLVSGAEDGSLQGWAL 1997


>gi|21071067 TBP-associated factor 5 [Homo sapiens]
          Length = 800

 Score = 37.4 bits (85), Expect = 0.029
 Identities = 33/115 (28%), Positives = 54/115 (46%), Gaps = 15/115 (13%)

Query: 107 NSRQVVCGTKCNTLFVVDVESGHIARIPLLRDSEARLAQDQQGCGIHAIELNPSKTLLAT 166
           NS  V  G+   T+ + DV +G+  RI              +G  IH++  +P+   LAT
Sbjct: 638 NSNYVATGSADRTVRLWDVLNGNCVRI----------FTGHKG-PIHSLTFSPNGRFLAT 686

Query: 167 GGENPNSLAIYQLPSLDPLCLGDRHGHKDWIFAVAWLSD-TVAVSGSRDGTVALW 220
           G  +   L ++ +     L +G+  GH D + ++ +  D  +  SGS D TV LW
Sbjct: 687 GATDGRVL-LWDIGH--GLMVGELKGHTDTVCSLRFSRDGEILASGSMDNTVRLW 738


>gi|55743149 WD repeat domain 17 isoform 2 [Homo sapiens]
          Length = 1298

 Score = 37.4 bits (85), Expect = 0.029
 Identities = 26/69 (37%), Positives = 35/69 (50%), Gaps = 5/69 (7%)

Query: 160 SKTLLATGGENPNSLAIYQLPSLD-PLCLGDRHGHKDWIFAVAW--LSDTVAVSGSRDGT 216
           +K ++ATG E+ N    Y   S D PL +    GH   +F V W  L + +  SGS DGT
Sbjct: 509 NKDMIATGCEDTNVRVYYVATSSDQPLKVFS--GHTAKVFHVKWSPLREGILCSGSDDGT 566

Query: 217 VALWRMDPD 225
           V +W    D
Sbjct: 567 VRIWDYTQD 575


>gi|31317311 WD repeat domain 17 isoform 1 [Homo sapiens]
          Length = 1322

 Score = 37.4 bits (85), Expect = 0.029
 Identities = 26/69 (37%), Positives = 35/69 (50%), Gaps = 5/69 (7%)

Query: 160 SKTLLATGGENPNSLAIYQLPSLD-PLCLGDRHGHKDWIFAVAW--LSDTVAVSGSRDGT 216
           +K ++ATG E+ N    Y   S D PL +    GH   +F V W  L + +  SGS DGT
Sbjct: 533 NKDMIATGCEDTNVRVYYVATSSDQPLKVFS--GHTAKVFHVKWSPLREGILCSGSDDGT 590

Query: 217 VALWRMDPD 225
           V +W    D
Sbjct: 591 VRIWDYTQD 599


>gi|118402582 cell division cycle 20 [Homo sapiens]
          Length = 499

 Score = 37.0 bits (84), Expect = 0.038
 Identities = 40/136 (29%), Positives = 64/136 (47%), Gaps = 21/136 (15%)

Query: 279 AVSLDGYFHLWKAGSA-LSRLLSIRLP--YFRDNVCLTYCDDMSVYAVGSHS-HVSFLDL 334
           AV+LD   +LW A S  + +LL +  P  Y      + +  + +  AVG+ S  V   D+
Sbjct: 199 AVALDNSVYLWSASSGDILQLLQMEQPGEYISS---VAWIKEGNYLAVGTSSAEVQLWDV 255

Query: 335 RQDQQNIRPLCSREGGTGVRSLSFYRHIITVGTGQGSLLFYDVRAQKFLEERASATLESS 394
           +Q Q+ +R + S     G  SLS+  +I++ G+  G +  +DVR    + E   ATL   
Sbjct: 256 QQ-QKRLRNMTSHSARVG--SLSWNSYILSSGSRSGHIHHHDVR----VAEHHVATLSGH 308

Query: 395 SGPARRKLRLACGRGW 410
           S       +  CG  W
Sbjct: 309 S-------QEVCGLRW 317


>gi|19913371 transducin (beta)-like 1 X-linked receptor 1 [Homo
           sapiens]
          Length = 514

 Score = 37.0 bits (84), Expect = 0.038
 Identities = 33/118 (27%), Positives = 54/118 (45%), Gaps = 17/118 (14%)

Query: 192 GHKDWIFAVAW--LSDTVAVSGSRDGTVALWRMDPDKFDDTVAWHSEVGLPVYAHIRPRD 249
           GH+  +F  AW  +SD +A SGS D T  +W +     +++ +  +++ L        +D
Sbjct: 167 GHESEVFICAWNPVSDLLA-SGSGDSTARIWNLS----ENSTSGSTQLVLRHCIREGGQD 221

Query: 250 VEAIPRAIINPSNRKVRALACGGKNQELGAVSLDGYFHLW-KAGSALSRLLSIRLPYF 306
           V         PSN+ V +L    +   L   S DG+  +W K G+  S L   + P F
Sbjct: 222 V---------PSNKDVTSLDWNSEGTLLATGSYDGFARIWTKDGNLASTLGQHKGPIF 270



 Score = 33.1 bits (74), Expect = 0.55
 Identities = 27/102 (26%), Positives = 48/102 (47%), Gaps = 16/102 (15%)

Query: 152 IHAIELNPSKTLLATGGENPNSLAIYQLPSLDPLCLGDRHGHKDWIFAVAWL-------- 203
           ++AI+ +P+  LLA+  ++  +L I+ +   +  C+ D   H   I+ + W         
Sbjct: 352 VNAIKWDPTGNLLASCSDDM-TLKIWSMKQDN--CVHDLQAHNKEIYTIKWSPTGPGTNN 408

Query: 204 --SDTVAVSGSRDGTVALWRMDPDKFDDTVAWHSEVGLPVYA 243
             ++ +  S S D TV LW +D      T+  H E   PVY+
Sbjct: 409 PNANLMLASASFDSTVRLWDVDRGICIHTLTKHQE---PVYS 447


>gi|19913369 transducin beta-like 3 [Homo sapiens]
          Length = 808

 Score = 37.0 bits (84), Expect = 0.038
 Identities = 26/83 (31%), Positives = 43/83 (51%), Gaps = 7/83 (8%)

Query: 144 AQDQQGC---GIHAIELNPSKTLLATGGENPNSLAIYQLPSLDPLCLGDRHGHKDWIFAV 200
           AQ  Q C    I+++ + P+  LLATG ++  +  ++ LP      LG   GH+  ++ V
Sbjct: 471 AQTTQRCHDKDINSVAIAPNDKLLATGSQD-RTAKLWALPQCQ--LLGVFSGHRRGLWCV 527

Query: 201 AWLS-DTVAVSGSRDGTVALWRM 222
            +   D V  + S DGT+ LW +
Sbjct: 528 QFSPMDQVLATASADGTIKLWAL 550


>gi|11055998 guanine nucleotide-binding protein, beta-4 subunit
           [Homo sapiens]
          Length = 340

 Score = 36.6 bits (83), Expect = 0.049
 Identities = 59/242 (24%), Positives = 98/242 (40%), Gaps = 32/242 (13%)

Query: 85  ELLTERQLELGTVNKVFASQW-LNSRQVVCGTKCNTLFVVDVESGHIARIPLLRDSEARL 143
           ++ T R L  G + K++A  W  +SR +V  ++   L + D  + +      LR S    
Sbjct: 44  QMRTRRTLR-GHLAKIYAMHWGYDSRLLVSASQDGKLIIWDSYTTNKMHAIPLRSS---- 98

Query: 144 AQDQQGCGIHAIELNPSKTLLATGGENPNSLAIYQLPSLDPLCLGDRH--GHKDWIFAVA 201
                   +      PS   +A GG + N  +IY L + +      R   GH  ++    
Sbjct: 99  -------WVMTCAYAPSGNYVACGGLD-NICSIYNLKTREGNVRVSRELPGHTGYLSCCR 150

Query: 202 WLSDTVAVSGSRDGTVALWRMDPDKFDDTVAWHSEVGLPVYAHIRPRDVEAIPRAIINPS 261
           +L D+  V+ S D T ALW ++  +   T   HS  G  +   + P D+        + S
Sbjct: 151 FLDDSQIVTSSGDTTCALWDIETAQQTTTFTGHS--GDVMSLSLSP-DMRTFVSGACDAS 207

Query: 262 NR--KVRALAC----GGKNQELGAVSL--DGYFHLWKAGSALSRLLSIR-----LPYFRD 308
           ++   +R   C     G   ++ AVS   +GY     +  A  RL  +R     L Y  D
Sbjct: 208 SKLWDIRDGMCRQSFTGHVSDINAVSFFPNGYAFATGSDDATCRLFDLRADQELLLYSHD 267

Query: 309 NV 310
           N+
Sbjct: 268 NI 269


>gi|48928050 F-box and WD repeat domain containing 11 isoform C
           [Homo sapiens]
          Length = 542

 Score = 36.2 bits (82), Expect = 0.065
 Identities = 24/89 (26%), Positives = 45/89 (50%), Gaps = 6/89 (6%)

Query: 151 GIHAIELNPSKTLLATGGENPNSLAIYQLPSLDPLCLGDRHGHKDWIFAVAWLSDTVAVS 210
           G++ ++ +  K +    G   NS+ I+   SL+  CL    GH   +  + +  + V V+
Sbjct: 242 GVYCLQYDDEKII---SGLRDNSIKIWDKTSLE--CLKVLTGHTGSVLCLQY-DERVIVT 295

Query: 211 GSRDGTVALWRMDPDKFDDTVAWHSEVGL 239
           GS D TV +W ++  +  +T+  H+E  L
Sbjct: 296 GSSDSTVRVWDVNTGEVLNTLIHHNEAVL 324


>gi|213021190 transducin beta-like 1X isoform b [Homo sapiens]
          Length = 526

 Score = 36.2 bits (82), Expect = 0.065
 Identities = 28/102 (27%), Positives = 48/102 (47%), Gaps = 16/102 (15%)

Query: 152 IHAIELNPSKTLLATGGENPNSLAIYQLPSLDPLCLGDRHGHKDWIFAVAWL-------- 203
           ++AI+ +PS  LLA+  ++  +L I+ +     +C+ D   H   I+ + W         
Sbjct: 364 VNAIKWDPSGMLLASCSDDM-TLKIWSMKQ--EVCIHDLQAHNKEIYTIKWSPTGPATSN 420

Query: 204 --SDTVAVSGSRDGTVALWRMDPDKFDDTVAWHSEVGLPVYA 243
             S+ +  S S D TV LW ++      T+  H E   PVY+
Sbjct: 421 PNSNIMLASASFDSTVRLWDIERGVCTHTLTKHQE---PVYS 459



 Score = 32.7 bits (73), Expect = 0.71
 Identities = 29/110 (26%), Positives = 47/110 (42%), Gaps = 16/110 (14%)

Query: 192 GHKDWIFAVAW--LSDTVAVSGSRDGTVALWRMDPDKFDDTVAWHSEVGLPVYAHIRPRD 249
           GH+  +F  AW  +SD +A SGS D T  +W ++    +++    +++ L         D
Sbjct: 179 GHESEVFICAWNPVSDLLA-SGSGDSTARIWNLN----ENSNGGSTQLVLRHCIREGGHD 233

Query: 250 VEAIPRAIINPSNRKVRALACGGKNQELGAVSLDGYFHLWKAGSALSRLL 299
           V         PSN+ V +L        L   S DG+  +W     L+  L
Sbjct: 234 V---------PSNKDVTSLDWNTNGTLLATGSYDGFARIWTEDGNLASTL 274


>gi|213021188 transducin beta-like 1X isoform b [Homo sapiens]
          Length = 526

 Score = 36.2 bits (82), Expect = 0.065
 Identities = 28/102 (27%), Positives = 48/102 (47%), Gaps = 16/102 (15%)

Query: 152 IHAIELNPSKTLLATGGENPNSLAIYQLPSLDPLCLGDRHGHKDWIFAVAWL-------- 203
           ++AI+ +PS  LLA+  ++  +L I+ +     +C+ D   H   I+ + W         
Sbjct: 364 VNAIKWDPSGMLLASCSDDM-TLKIWSMKQ--EVCIHDLQAHNKEIYTIKWSPTGPATSN 420

Query: 204 --SDTVAVSGSRDGTVALWRMDPDKFDDTVAWHSEVGLPVYA 243
             S+ +  S S D TV LW ++      T+  H E   PVY+
Sbjct: 421 PNSNIMLASASFDSTVRLWDIERGVCTHTLTKHQE---PVYS 459



 Score = 32.7 bits (73), Expect = 0.71
 Identities = 29/110 (26%), Positives = 47/110 (42%), Gaps = 16/110 (14%)

Query: 192 GHKDWIFAVAW--LSDTVAVSGSRDGTVALWRMDPDKFDDTVAWHSEVGLPVYAHIRPRD 249
           GH+  +F  AW  +SD +A SGS D T  +W ++    +++    +++ L         D
Sbjct: 179 GHESEVFICAWNPVSDLLA-SGSGDSTARIWNLN----ENSNGGSTQLVLRHCIREGGHD 233

Query: 250 VEAIPRAIINPSNRKVRALACGGKNQELGAVSLDGYFHLWKAGSALSRLL 299
           V         PSN+ V +L        L   S DG+  +W     L+  L
Sbjct: 234 V---------PSNKDVTSLDWNTNGTLLATGSYDGFARIWTEDGNLASTL 274


>gi|213021186 transducin beta-like 1X isoform a [Homo sapiens]
          Length = 577

 Score = 36.2 bits (82), Expect = 0.065
 Identities = 28/102 (27%), Positives = 48/102 (47%), Gaps = 16/102 (15%)

Query: 152 IHAIELNPSKTLLATGGENPNSLAIYQLPSLDPLCLGDRHGHKDWIFAVAWL-------- 203
           ++AI+ +PS  LLA+  ++  +L I+ +     +C+ D   H   I+ + W         
Sbjct: 415 VNAIKWDPSGMLLASCSDDM-TLKIWSMKQ--EVCIHDLQAHNKEIYTIKWSPTGPATSN 471

Query: 204 --SDTVAVSGSRDGTVALWRMDPDKFDDTVAWHSEVGLPVYA 243
             S+ +  S S D TV LW ++      T+  H E   PVY+
Sbjct: 472 PNSNIMLASASFDSTVRLWDIERGVCTHTLTKHQE---PVYS 510



 Score = 32.7 bits (73), Expect = 0.71
 Identities = 29/110 (26%), Positives = 47/110 (42%), Gaps = 16/110 (14%)

Query: 192 GHKDWIFAVAW--LSDTVAVSGSRDGTVALWRMDPDKFDDTVAWHSEVGLPVYAHIRPRD 249
           GH+  +F  AW  +SD +A SGS D T  +W ++    +++    +++ L         D
Sbjct: 230 GHESEVFICAWNPVSDLLA-SGSGDSTARIWNLN----ENSNGGSTQLVLRHCIREGGHD 284

Query: 250 VEAIPRAIINPSNRKVRALACGGKNQELGAVSLDGYFHLWKAGSALSRLL 299
           V         PSN+ V +L        L   S DG+  +W     L+  L
Sbjct: 285 V---------PSNKDVTSLDWNTNGTLLATGSYDGFARIWTEDGNLASTL 325


>gi|5032159 transducin beta-like 1X isoform a [Homo sapiens]
          Length = 577

 Score = 36.2 bits (82), Expect = 0.065
 Identities = 28/102 (27%), Positives = 48/102 (47%), Gaps = 16/102 (15%)

Query: 152 IHAIELNPSKTLLATGGENPNSLAIYQLPSLDPLCLGDRHGHKDWIFAVAWL-------- 203
           ++AI+ +PS  LLA+  ++  +L I+ +     +C+ D   H   I+ + W         
Sbjct: 415 VNAIKWDPSGMLLASCSDDM-TLKIWSMKQ--EVCIHDLQAHNKEIYTIKWSPTGPATSN 471

Query: 204 --SDTVAVSGSRDGTVALWRMDPDKFDDTVAWHSEVGLPVYA 243
             S+ +  S S D TV LW ++      T+  H E   PVY+
Sbjct: 472 PNSNIMLASASFDSTVRLWDIERGVCTHTLTKHQE---PVYS 510



 Score = 32.7 bits (73), Expect = 0.71
 Identities = 29/110 (26%), Positives = 47/110 (42%), Gaps = 16/110 (14%)

Query: 192 GHKDWIFAVAW--LSDTVAVSGSRDGTVALWRMDPDKFDDTVAWHSEVGLPVYAHIRPRD 249
           GH+  +F  AW  +SD +A SGS D T  +W ++    +++    +++ L         D
Sbjct: 230 GHESEVFICAWNPVSDLLA-SGSGDSTARIWNLN----ENSNGGSTQLVLRHCIREGGHD 284

Query: 250 VEAIPRAIINPSNRKVRALACGGKNQELGAVSLDGYFHLWKAGSALSRLL 299
           V         PSN+ V +L        L   S DG+  +W     L+  L
Sbjct: 285 V---------PSNKDVTSLDWNTNGTLLATGSYDGFARIWTEDGNLASTL 325


>gi|48928048 F-box and WD repeat domain containing 11 isoform A
           [Homo sapiens]
          Length = 508

 Score = 36.2 bits (82), Expect = 0.065
 Identities = 24/89 (26%), Positives = 45/89 (50%), Gaps = 6/89 (6%)

Query: 151 GIHAIELNPSKTLLATGGENPNSLAIYQLPSLDPLCLGDRHGHKDWIFAVAWLSDTVAVS 210
           G++ ++ +  K +    G   NS+ I+   SL+  CL    GH   +  + +  + V V+
Sbjct: 208 GVYCLQYDDEKII---SGLRDNSIKIWDKTSLE--CLKVLTGHTGSVLCLQY-DERVIVT 261

Query: 211 GSRDGTVALWRMDPDKFDDTVAWHSEVGL 239
           GS D TV +W ++  +  +T+  H+E  L
Sbjct: 262 GSSDSTVRVWDVNTGEVLNTLIHHNEAVL 290


>gi|48928046 F-box and WD repeat domain containing 11 isoform B
           [Homo sapiens]
          Length = 529

 Score = 36.2 bits (82), Expect = 0.065
 Identities = 24/89 (26%), Positives = 45/89 (50%), Gaps = 6/89 (6%)

Query: 151 GIHAIELNPSKTLLATGGENPNSLAIYQLPSLDPLCLGDRHGHKDWIFAVAWLSDTVAVS 210
           G++ ++ +  K +    G   NS+ I+   SL+  CL    GH   +  + +  + V V+
Sbjct: 229 GVYCLQYDDEKII---SGLRDNSIKIWDKTSLE--CLKVLTGHTGSVLCLQY-DERVIVT 282

Query: 211 GSRDGTVALWRMDPDKFDDTVAWHSEVGL 239
           GS D TV +W ++  +  +T+  H+E  L
Sbjct: 283 GSSDSTVRVWDVNTGEVLNTLIHHNEAVL 311


>gi|19913367 transducin beta-like 1Y [Homo sapiens]
          Length = 522

 Score = 35.8 bits (81), Expect = 0.084
 Identities = 36/152 (23%), Positives = 58/152 (38%), Gaps = 40/152 (26%)

Query: 152 IHAIELNPSKTLLATGGENPNSLAIYQLPSLDPLCLGDRHGHKDWIFAVAWL-------- 203
           ++AI+ +PS  LLA+  ++  +L I+ +      C+ D   H   I+ + W         
Sbjct: 362 VNAIKWDPSGMLLASCSDDM-TLKIWSMKQ--DACVHDLQAHSKEIYTIKWSPTGPATSN 418

Query: 204 --SDTVAVSGSRDGTVALWRMDPDKFDDTVAWHSEVGLPVYAHIRPRDVEAIPRAIINPS 261
             S  +  S S D TV LW ++      T+  H E   PVY                   
Sbjct: 419 PNSSIMLASASFDSTVRLWDVEQGVCTHTLMKHQE---PVY------------------- 456

Query: 262 NRKVRALACGGKNQELGAVSLDGYFHLWKAGS 293
                ++A     + L + S D Y H+W   S
Sbjct: 457 -----SVAFSPDGKYLASGSFDKYVHIWNTQS 483



 Score = 33.1 bits (74), Expect = 0.55
 Identities = 29/110 (26%), Positives = 47/110 (42%), Gaps = 16/110 (14%)

Query: 192 GHKDWIFAVAW--LSDTVAVSGSRDGTVALWRMDPDKFDDTVAWHSEVGLPVYAHIRPRD 249
           GH+  +F  AW  +SD +A SGS D T  +W ++    +++    +++ L         D
Sbjct: 177 GHESEVFICAWNPVSDLLA-SGSGDSTARIWNLN----ENSNGGSTQLVLRHCIREGGHD 231

Query: 250 VEAIPRAIINPSNRKVRALACGGKNQELGAVSLDGYFHLWKAGSALSRLL 299
           V         PSN+ V +L        L   S DG+  +W     L+  L
Sbjct: 232 V---------PSNKDVTSLDWNSDGTLLAMGSYDGFARIWTENGNLASTL 272


>gi|19913365 transducin beta-like 1Y [Homo sapiens]
          Length = 522

 Score = 35.8 bits (81), Expect = 0.084
 Identities = 36/152 (23%), Positives = 58/152 (38%), Gaps = 40/152 (26%)

Query: 152 IHAIELNPSKTLLATGGENPNSLAIYQLPSLDPLCLGDRHGHKDWIFAVAWL-------- 203
           ++AI+ +PS  LLA+  ++  +L I+ +      C+ D   H   I+ + W         
Sbjct: 362 VNAIKWDPSGMLLASCSDDM-TLKIWSMKQ--DACVHDLQAHSKEIYTIKWSPTGPATSN 418

Query: 204 --SDTVAVSGSRDGTVALWRMDPDKFDDTVAWHSEVGLPVYAHIRPRDVEAIPRAIINPS 261
             S  +  S S D TV LW ++      T+  H E   PVY                   
Sbjct: 419 PNSSIMLASASFDSTVRLWDVEQGVCTHTLMKHQE---PVY------------------- 456

Query: 262 NRKVRALACGGKNQELGAVSLDGYFHLWKAGS 293
                ++A     + L + S D Y H+W   S
Sbjct: 457 -----SVAFSPDGKYLASGSFDKYVHIWNTQS 483



 Score = 33.1 bits (74), Expect = 0.55
 Identities = 29/110 (26%), Positives = 47/110 (42%), Gaps = 16/110 (14%)

Query: 192 GHKDWIFAVAW--LSDTVAVSGSRDGTVALWRMDPDKFDDTVAWHSEVGLPVYAHIRPRD 249
           GH+  +F  AW  +SD +A SGS D T  +W ++    +++    +++ L         D
Sbjct: 177 GHESEVFICAWNPVSDLLA-SGSGDSTARIWNLN----ENSNGGSTQLVLRHCIREGGHD 231

Query: 250 VEAIPRAIINPSNRKVRALACGGKNQELGAVSLDGYFHLWKAGSALSRLL 299
           V         PSN+ V +L        L   S DG+  +W     L+  L
Sbjct: 232 V---------PSNKDVTSLDWNSDGTLLAMGSYDGFARIWTENGNLASTL 272


>gi|15150805 transducin beta-like 1Y [Homo sapiens]
          Length = 522

 Score = 35.8 bits (81), Expect = 0.084
 Identities = 36/152 (23%), Positives = 58/152 (38%), Gaps = 40/152 (26%)

Query: 152 IHAIELNPSKTLLATGGENPNSLAIYQLPSLDPLCLGDRHGHKDWIFAVAWL-------- 203
           ++AI+ +PS  LLA+  ++  +L I+ +      C+ D   H   I+ + W         
Sbjct: 362 VNAIKWDPSGMLLASCSDDM-TLKIWSMKQ--DACVHDLQAHSKEIYTIKWSPTGPATSN 418

Query: 204 --SDTVAVSGSRDGTVALWRMDPDKFDDTVAWHSEVGLPVYAHIRPRDVEAIPRAIINPS 261
             S  +  S S D TV LW ++      T+  H E   PVY                   
Sbjct: 419 PNSSIMLASASFDSTVRLWDVEQGVCTHTLMKHQE---PVY------------------- 456

Query: 262 NRKVRALACGGKNQELGAVSLDGYFHLWKAGS 293
                ++A     + L + S D Y H+W   S
Sbjct: 457 -----SVAFSPDGKYLASGSFDKYVHIWNTQS 483



 Score = 33.1 bits (74), Expect = 0.55
 Identities = 29/110 (26%), Positives = 47/110 (42%), Gaps = 16/110 (14%)

Query: 192 GHKDWIFAVAW--LSDTVAVSGSRDGTVALWRMDPDKFDDTVAWHSEVGLPVYAHIRPRD 249
           GH+  +F  AW  +SD +A SGS D T  +W ++    +++    +++ L         D
Sbjct: 177 GHESEVFICAWNPVSDLLA-SGSGDSTARIWNLN----ENSNGGSTQLVLRHCIREGGHD 231

Query: 250 VEAIPRAIINPSNRKVRALACGGKNQELGAVSLDGYFHLWKAGSALSRLL 299
           V         PSN+ V +L        L   S DG+  +W     L+  L
Sbjct: 232 V---------PSNKDVTSLDWNSDGTLLAMGSYDGFARIWTENGNLASTL 272


>gi|11321585 guanine nucleotide-binding protein, beta-1 subunit
           [Homo sapiens]
          Length = 340

 Score = 35.4 bits (80), Expect = 0.11
 Identities = 38/155 (24%), Positives = 65/155 (41%), Gaps = 18/155 (11%)

Query: 85  ELLTERQLELGTVNKVFASQW-LNSRQVVCGTKCNTLFVVD-VESGHIARIPLLRDSEAR 142
           ++ T R L  G + K++A  W  +SR +V  ++   L + D   +  +  IPL       
Sbjct: 44  QMRTRRTLR-GHLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPL------- 95

Query: 143 LAQDQQGCGIHAIELNPSKTLLATGGENPNSLAIYQLPSLDPLCLGDRH--GHKDWIFAV 200
                +   +      PS   +A GG + N  +IY L + +      R   GH  ++   
Sbjct: 96  -----RSSWVMTCAYAPSGNYVACGGLD-NICSIYNLKTREGNVRVSRELAGHTGYLSCC 149

Query: 201 AWLSDTVAVSGSRDGTVALWRMDPDKFDDTVAWHS 235
            +L D   V+ S D T ALW ++  +   T   H+
Sbjct: 150 RFLDDNQIVTSSGDTTCALWDIETGQQTTTFTGHT 184


>gi|38569484 kinesin family member 21A [Homo sapiens]
          Length = 1661

 Score = 35.4 bits (80), Expect = 0.11
 Identities = 32/129 (24%), Positives = 56/129 (43%), Gaps = 14/129 (10%)

Query: 96   TVNKVFASQWLNSRQVVCGTKCNTLFVVDVESGHIARIPLLRDSEARLAQDQQGCGIHAI 155
            TV+++ + Q L    ++ G+K + + + DV  G +  +     S     +     GI A+
Sbjct: 1486 TVDQISSGQDL----IITGSKDHYIKMFDVTEGALGTV-----SPTHNFEPPHYDGIEAL 1536

Query: 156  ELNPSKTLLATGGENPNSLAIYQLPSLDPLCLGDRHGHKDWIFAVAWLSD-TVAVSGSRD 214
             +          G   N +  + L   D L     + HKDW+ A+  + D  V +SG R 
Sbjct: 1537 TIQGDNLF---SGSRDNGIKKWDLTQKD-LLQQVPNAHKDWVCALGVVPDHPVLLSGCRG 1592

Query: 215  GTVALWRMD 223
            G + +W MD
Sbjct: 1593 GILKVWNMD 1601


>gi|17402902 guanine nucleotide binding protein beta-subunit-like
           polypeptide [Homo sapiens]
          Length = 327

 Score = 35.4 bits (80), Expect = 0.11
 Identities = 19/74 (25%), Positives = 40/74 (54%), Gaps = 3/74 (4%)

Query: 151 GIHAIELNPSKTLLATGGENPNSLAIYQLPSLDPLCLGDRHGHKDWIFAVAWLSDTVAVS 210
           GI  + + P + +LAT G + + + ++   ++ PL +   H     +  VA+ +D +  +
Sbjct: 255 GIAEVTIRPDRKILATAGWD-HRIRVFHWRTMQPLAVLAFHSAA--VQCVAFTADGLLAA 311

Query: 211 GSRDGTVALWRMDP 224
           GS+D  ++LW + P
Sbjct: 312 GSKDQRISLWSLYP 325


>gi|153791630 bromodomain and WD repeat domain containing 3 [Homo
           sapiens]
          Length = 1802

 Score = 35.4 bits (80), Expect = 0.11
 Identities = 21/72 (29%), Positives = 35/72 (48%), Gaps = 3/72 (4%)

Query: 163 LLATGGENPNSLAIYQLPSLDPLCLGDRHGHKDWIFAVAWLSDTVA---VSGSRDGTVAL 219
           +  T G   + + IY L S  P  + +   H D + AV + ++  +   VSGSRDGT  +
Sbjct: 331 MFITTGSTDHVIRIYYLGSEVPEKIAELESHTDKVVAVQFCNNGDSLRFVSGSRDGTARI 390

Query: 220 WRMDPDKFDDTV 231
           W+    ++   V
Sbjct: 391 WQYQQQEWKSIV 402


>gi|20357529 guanine nucleotide-binding protein, beta-2 subunit
           [Homo sapiens]
          Length = 340

 Score = 35.0 bits (79), Expect = 0.14
 Identities = 58/243 (23%), Positives = 95/243 (39%), Gaps = 34/243 (13%)

Query: 85  ELLTERQLELGTVNKVFASQW-LNSRQVVCGTKCNTLFVVD-VESGHIARIPLLRDSEAR 142
           ++ T R L  G + K++A  W  +SR +V  ++   L + D   +  +  IPL       
Sbjct: 44  QMRTRRTLR-GHLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPL------- 95

Query: 143 LAQDQQGCGIHAIELNPSKTLLATGGENPNSLAIYQLPSLDPLCLGDRH--GHKDWIFAV 200
                +   +      PS   +A GG + N  +IY L + +      R   GH  ++   
Sbjct: 96  -----RSSWVMTCAYAPSGNFVACGGLD-NICSIYSLKTREGNVRVSRELPGHTGYLSCC 149

Query: 201 AWLSDTVAVSGSRDGTVALWRMDPDKFDDTVAWHSEVGLPVYAHIRPRDVEAIPRAIINP 260
            +L D   ++ S D T ALW  D +    TV +    G  +   + P D         + 
Sbjct: 150 RFLDDNQIITSSGDTTCALW--DIETGQQTVGFAGHSGDVMSLSLAP-DGRTFVSGACDA 206

Query: 261 SNR--KVRALACG----GKNQELGAVSL--DGYFHLWKAGSALSRLLSIR-----LPYFR 307
           S +   VR   C     G   ++ AV+   +GY     +  A  RL  +R     L Y  
Sbjct: 207 SIKLWDVRDSMCRQTFIGHESDINAVAFFPNGYAFTTGSDDATCRLFDLRADQELLMYSH 266

Query: 308 DNV 310
           DN+
Sbjct: 267 DNI 269


>gi|4505895 pleiotropic regulator 1 (PRL1 homolog, Arabidopsis)
           [Homo sapiens]
          Length = 514

 Score = 33.5 bits (75), Expect = 0.42
 Identities = 28/111 (25%), Positives = 54/111 (48%), Gaps = 15/111 (13%)

Query: 110 QVVCGTKCNTLFVVDVESGHIARIPLLRDSEARLAQDQQGCGIHAIELNPSKTLLATGGE 169
           Q++ G+   T+ + D+ +G   R+ L    ++          + A+ L+P     A+G  
Sbjct: 344 QIITGSHDTTIRLWDLVAGK-TRVTLTNHKKS----------VRAVVLHPRHYTFASG-- 390

Query: 170 NPNSLAIYQLPSLDPLCLGDRHGHKDWIFAVAWLSDTVAVSGSRDGTVALW 220
           +P+++  ++ P  D   + +  GH   I  +   SD V VSG+ +GT+ LW
Sbjct: 391 SPDNIKQWKFP--DGSFIQNLSGHNAIINTLTVNSDGVLVSGADNGTMHLW 439


>gi|4759276 RNA, U3 small nucleolar interacting protein 2 [Homo
           sapiens]
          Length = 475

 Score = 33.1 bits (74), Expect = 0.55
 Identities = 17/61 (27%), Positives = 32/61 (52%), Gaps = 3/61 (4%)

Query: 160 SKTLLATGGENPNSLAIYQLPSLDPLCLGDRHGHKDWIFAVAWLSDTVAVSGSRDGTVAL 219
           S+    T G    ++ ++++P    L     +GH+  I  +  +++   VSG+ DG+VAL
Sbjct: 293 SRECCVTAGGRDGTVRVWKIPEESQLVF---YGHQGSIDCIHLINEEHMVSGADDGSVAL 349

Query: 220 W 220
           W
Sbjct: 350 W 350


>gi|53729352 WD repeat-containing protein 1 isoform 2 [Homo sapiens]
          Length = 466

 Score = 33.1 bits (74), Expect = 0.55
 Identities = 35/160 (21%), Positives = 65/160 (40%), Gaps = 24/160 (15%)

Query: 152 IHAIELNPSKTLLATGGENPNSLAIYQLPSLDPLC-LGDRHGHKDWIFAVAWLSD-TVAV 209
           ++ +  +P     AT   +   + IY   + + +C LG    H   I+A++W  D T  +
Sbjct: 52  VNCVRFSPDGNRFATASAD-GQIYIYDGKTGEKVCALGGSKAHDGGIYAISWSPDSTHLL 110

Query: 210 SGSRDGTVALWRMDPDKFDDT-------------VAWHSE----VGLPVYAHIRPRDVEA 252
           S S D T  +W +  +    T               W  +    V L  Y +   R+  +
Sbjct: 111 SASGDKTSKIWDVSVNSVVSTFPMGSTVLDQQLGCLWQKDHLLSVSLSGYINYLDRNNPS 170

Query: 253 IPRAIINPSNRKVRALAC---GGKNQELGAVSLDGYFHLW 289
            P  +I   ++ ++ L     GGK+  + + S DG+ + W
Sbjct: 171 KPLHVIKGHSKSIQCLTVHKNGGKSY-IYSGSHDGHINYW 209


>gi|9257257 WD repeat-containing protein 1 isoform 1 [Homo sapiens]
          Length = 606

 Score = 33.1 bits (74), Expect = 0.55
 Identities = 35/160 (21%), Positives = 65/160 (40%), Gaps = 24/160 (15%)

Query: 152 IHAIELNPSKTLLATGGENPNSLAIYQLPSLDPLC-LGDRHGHKDWIFAVAWLSD-TVAV 209
           ++ +  +P     AT   +   + IY   + + +C LG    H   I+A++W  D T  +
Sbjct: 192 VNCVRFSPDGNRFATASAD-GQIYIYDGKTGEKVCALGGSKAHDGGIYAISWSPDSTHLL 250

Query: 210 SGSRDGTVALWRMDPDKFDDT-------------VAWHSE----VGLPVYAHIRPRDVEA 252
           S S D T  +W +  +    T               W  +    V L  Y +   R+  +
Sbjct: 251 SASGDKTSKIWDVSVNSVVSTFPMGSTVLDQQLGCLWQKDHLLSVSLSGYINYLDRNNPS 310

Query: 253 IPRAIINPSNRKVRALAC---GGKNQELGAVSLDGYFHLW 289
            P  +I   ++ ++ L     GGK+  + + S DG+ + W
Sbjct: 311 KPLHVIKGHSKSIQCLTVHKNGGKSY-IYSGSHDGHINYW 349


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.320    0.137    0.430 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 19,080,906
Number of Sequences: 37866
Number of extensions: 883638
Number of successful extensions: 2121
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 4
Number of HSP's successfully gapped in prelim test: 72
Number of HSP's that attempted gapping in prelim test: 2030
Number of HSP's gapped (non-prelim): 161
length of query: 463
length of database: 18,247,518
effective HSP length: 106
effective length of query: 357
effective length of database: 14,233,722
effective search space: 5081438754
effective search space used: 5081438754
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.