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Search of human proteins with 71043876
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|71043876 undifferentiated embryonic cell transcription
factor 1 [Homo sapiens]
(341 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|71043876 undifferentiated embryonic cell transcription factor... 707 0.0
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 69 5e-12
gi|7662046 myeloid/lymphoid or mixed-lineage leukemia 4 [Homo sa... 68 1e-11
gi|189181724 proteoglycan 4 isoform D [Homo sapiens] 65 9e-11
gi|189181722 proteoglycan 4 isoform C [Homo sapiens] 65 9e-11
gi|189181720 proteoglycan 4 isoform B [Homo sapiens] 65 9e-11
gi|67190163 proteoglycan 4 isoform A [Homo sapiens] 65 9e-11
gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo ... 65 9e-11
gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 63 3e-10
gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi... 62 7e-10
gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens] 62 1e-09
gi|7706501 WW domain binding protein 11 [Homo sapiens] 59 5e-09
gi|163965366 nascent polypeptide-associated complex alpha subuni... 59 6e-09
gi|112734870 hypothetical protein LOC57648 [Homo sapiens] 59 8e-09
gi|39930517 sterile alpha motif domain containing 1 [Homo sapiens] 59 8e-09
gi|150170670 piccolo isoform 2 [Homo sapiens] 58 1e-08
gi|150378539 piccolo isoform 1 [Homo sapiens] 58 1e-08
gi|33356148 formin-like 1 [Homo sapiens] 58 1e-08
gi|24431933 reticulon 4 isoform B [Homo sapiens] 56 4e-08
gi|47519490 reticulon 4 isoform D [Homo sapiens] 56 4e-08
gi|24431935 reticulon 4 isoform A [Homo sapiens] 56 4e-08
gi|153792074 proline rich 12 [Homo sapiens] 56 4e-08
gi|33286446 opioid growth factor receptor [Homo sapiens] 55 9e-08
gi|51702526 Wiskott-Aldrich syndrome gene-like protein [Homo sap... 55 9e-08
gi|20986497 mitogen-activated protein kinase 7 isoform 1 [Homo s... 55 9e-08
gi|209529736 mitogen-activated protein kinase 7 isoform 1 [Homo ... 55 9e-08
gi|209529734 mitogen-activated protein kinase 7 isoform 1 [Homo ... 55 9e-08
gi|20986499 mitogen-activated protein kinase 7 isoform 2 [Homo s... 55 9e-08
gi|149158690 HLA-B associated transcript-2 [Homo sapiens] 54 2e-07
gi|4826998 splicing factor proline/glutamine rich (polypyrimidin... 54 2e-07
>gi|71043876 undifferentiated embryonic cell transcription factor 1
[Homo sapiens]
Length = 341
Score = 707 bits (1826), Expect = 0.0
Identities = 341/341 (100%), Positives = 341/341 (100%)
Query: 1 MLLRPRRPPPLAPPAPPSPASPDPEPRTPGDAPGTPPRRPASPSALGELGLPVSPGSAQR 60
MLLRPRRPPPLAPPAPPSPASPDPEPRTPGDAPGTPPRRPASPSALGELGLPVSPGSAQR
Sbjct: 1 MLLRPRRPPPLAPPAPPSPASPDPEPRTPGDAPGTPPRRPASPSALGELGLPVSPGSAQR 60
Query: 61 TPWSARETELLLGTLLQPAVWRALLLDRRQALPTYRRVSAALAQQQVRRTPAQCRRRYKF 120
TPWSARETELLLGTLLQPAVWRALLLDRRQALPTYRRVSAALAQQQVRRTPAQCRRRYKF
Sbjct: 61 TPWSARETELLLGTLLQPAVWRALLLDRRQALPTYRRVSAALAQQQVRRTPAQCRRRYKF 120
Query: 121 LKDKFREAHGQPPGPFDEQIRKLMGLLGDNGRKRPRRRSPGSGRPQRARRPVPNAHAPAP 180
LKDKFREAHGQPPGPFDEQIRKLMGLLGDNGRKRPRRRSPGSGRPQRARRPVPNAHAPAP
Sbjct: 121 LKDKFREAHGQPPGPFDEQIRKLMGLLGDNGRKRPRRRSPGSGRPQRARRPVPNAHAPAP 180
Query: 181 SEPDATPLPTARDRDADPTWTLRFSPSPPKSADASPAPGSPPAPAPTALATCIPEDRAPV 240
SEPDATPLPTARDRDADPTWTLRFSPSPPKSADASPAPGSPPAPAPTALATCIPEDRAPV
Sbjct: 181 SEPDATPLPTARDRDADPTWTLRFSPSPPKSADASPAPGSPPAPAPTALATCIPEDRAPV 240
Query: 241 RGPGSPPPPPAREDPDSPPGRPEDCAPPPAAPPSLNTALLQTLGHLGDIANILGPLRDQL 300
RGPGSPPPPPAREDPDSPPGRPEDCAPPPAAPPSLNTALLQTLGHLGDIANILGPLRDQL
Sbjct: 241 RGPGSPPPPPAREDPDSPPGRPEDCAPPPAAPPSLNTALLQTLGHLGDIANILGPLRDQL 300
Query: 301 LTLNQHVEQLRGAFDQTVSLAVGFILGSAAAERGVLRDPCQ 341
LTLNQHVEQLRGAFDQTVSLAVGFILGSAAAERGVLRDPCQ
Sbjct: 301 LTLNQHVEQLRGAFDQTVSLAVGFILGSAAAERGVLRDPCQ 341
>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo
sapiens]
Length = 1124
Score = 69.3 bits (168), Expect = 5e-12
Identities = 85/283 (30%), Positives = 101/283 (35%), Gaps = 47/283 (16%)
Query: 5 PRRPPPLAPPAPPSPASPDPEPRTPGDAPGTPPRRPASPSALGELGLPVSPGSAQRTPWS 64
P P P APPSP + P P TP PP+ P + ++ GLP P S TP
Sbjct: 561 PPCPAPCPLQAPPSPLTTPP-PETPSSIATPPPQAPPALASPPLQGLPSPPLSPLATP-- 617
Query: 65 ARETELLLGTLLQPAVWRALLLDRRQALPTYRRVSAALAQQQVRRTPAQCRRRYKFLKDK 124
P L L QA P+ S L+ A L+
Sbjct: 618 ------------PPQAPPXLALPPLQAPPS-PPASPPLSPLATPSPQAPNALAVHLLQAP 664
Query: 125 FREAHGQP-PGPFDEQIRKLMGLLGDNGRKRPRRRSPGSGRPQRARRPV---PNAHAPAP 180
F P PF + P P P A P+ P+ A P
Sbjct: 665 FSPPPSPPVQAPFSPPASPPVS---------PSATPPSQAPPSLAAPPLQVPPSPPASPP 715
Query: 181 SEPDATPLPTARDRDADPTWTLRFSPSPPKSADASPAPGSPPAPAPTALATCIPEDRAPV 240
P ATP P A A P L+ PSPP S SP+ +PP P LA AP
Sbjct: 716 MSPSATPPPQAPPPLAAPP--LQVPPSPPASPPMSPS-ATPPPRVPPLLA-------AP- 764
Query: 241 RGPGSPPPPPAREDPDSPPGRPEDCAPPPAAPPSLNTALLQTL 283
P PP P P SP +P PP APP+L T LQ L
Sbjct: 765 --PLQVPPSPPASLPMSPLAKP-----PPQAPPALATPPLQAL 800
Score = 65.1 bits (157), Expect = 9e-11
Identities = 77/285 (27%), Positives = 109/285 (38%), Gaps = 32/285 (11%)
Query: 4 RPRRPPPLAPPAPPSPASPDPEPRTPGDAPGTPPRRPASPSALGELGLPVSPGSAQR-TP 62
RP PP +PP + P P +PP + + A+ L P++ Q +
Sbjct: 446 RPASTPPDSPPL-----------QAPLSLPASPPLQTSLSPAVSPLSSPLTIHPLQALSS 494
Query: 63 WSARETELLLGTLLQPAVWRALLLDRRQALPTYRRVSAALAQQQVRRTPAQCRRRYKFLK 122
++ + L +L+ P L A P+ + A+L + P+ +
Sbjct: 495 LASHSPQAPLSSLIMP----PLETQSSLAPPSLQTPPASLTTPPLENLPSLAPPPLQTAS 550
Query: 123 DKFREAHGQ-PPGPFDEQIRKLMGLLGDNGRKRPR--RRSPGSGRPQRARRPVPNAHAPA 179
H + PP P ++ L + P P P A P+ +P
Sbjct: 551 APLTTPHLETPPCPAPCPLQAPPSPLTTPPPETPSSIATPPPQAPPALASPPLQGLPSP- 609
Query: 180 PSEPDATPLPTARDRDADPTWTLRFSPSPPKSADASPAPGSPPAPAPTALATCIPEDRAP 239
P P ATP P A A P L+ PSPP S SP +P AP ALA +
Sbjct: 610 PLSPLATPPPQAPPXLALP--PLQAPPSPPASPPLSPL-ATPSPQAPNALAVHL------ 660
Query: 240 VRGPGSPPPPPAREDPDSPPGRP---EDCAPPPAAPPSLNTALLQ 281
++ P SPPP P + P SPP P PP APPSL LQ
Sbjct: 661 LQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQ 705
Score = 58.9 bits (141), Expect = 6e-09
Identities = 88/329 (26%), Positives = 117/329 (35%), Gaps = 45/329 (13%)
Query: 5 PRRPPPLAPPAPPSPASPDPEPRTPGDAPG--TPPRRPASPSALGELGLPVSPGSAQRT- 61
P P P +S +P R P G PP + SP + SPG A T
Sbjct: 71 PESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVS------SPGRASGTT 124
Query: 62 -PWSARETELLLGTLLQPAVWRALLLDRRQALPTYRRVSAALAQQQVRRTPAQCRRRYKF 120
P + L + A +A +R AL R + +PA RR
Sbjct: 125 RPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTS-GPTPGTPSPAMARRSRAA 183
Query: 121 LKDKF--REAHGQPPGPFDEQIRKLMGLLGDNGRKRP-----RRRSPGSGRPQRARRPVP 173
+ R A P P E RK + ++ P RR S G G + A R +
Sbjct: 184 GTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLS 243
Query: 174 NA----HAPAPSEPDATPLPTARDRDADPT----WTLRFSPSPPKSADASPAPG------ 219
++ +PA S P A P A + P LR P DA+PA G
Sbjct: 244 SSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSP 303
Query: 220 -SPPAPAPTALATCIPEDRAPVRGPGSPPPPP--------AREDPDSPPGR---PEDCAP 267
+ P+P+ T P D A P + PP P A P +PP P A
Sbjct: 304 LATPSPSGTKARPVPPPDNAATPLPATLPPSPPLATPLPLAPPSPSAPPSLQTLPSPPAT 363
Query: 268 PPA-APPSLNTALLQTLGHLGDIANILGP 295
PP+ APPS+ T +Q L I I P
Sbjct: 364 PPSQAPPSMTTPPMQAPPSLQTIPPIQVP 392
Score = 55.5 bits (132), Expect = 7e-08
Identities = 71/273 (26%), Positives = 90/273 (32%), Gaps = 24/273 (8%)
Query: 8 PPPLAPP---APPSPASPDPEPRTPGDAPGTPPRRPASPSALGELGLPVSPGSAQRTPWS 64
PP APP APP P P P TPP + P A L +P SP ++ S
Sbjct: 691 PPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQVPPSPPASPPMSPS 750
Query: 65 ARETELLLGTLLQPAVWRALLLDRRQALPTYRRVSAALAQQQVRRTPAQCRRRYKFLKDK 124
A + L P + + P + LA+ + PA + L
Sbjct: 751 ATPPPRVPPLLAAPPL-------QVPPSPPASLPMSPLAKPPPQAPPALATPPLQALPSP 803
Query: 125 FREAHGQPPGPFDEQIRKLMGLLGDNGRKRPRRRSPGSGRPQRARRPVPNAHAPAPSEPD 184
GQ PF M L P + P P P P A +P P
Sbjct: 804 PASFPGQ--APFSPSASLPMSPLA----TPPPQAPPVLAAPLLQVPPSPPA-SPTLQAPR 856
Query: 185 ATPLPTARDRDADPTWTLRFSPSPPKSADASPAP--GSPPAPAPTALATCIPE-----DR 237
P P + P TL +P PP SP+ P ++ AT PE D
Sbjct: 857 RPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDS 916
Query: 238 APVRGPGSPPPPPAREDPDSPPGRPEDCAPPPA 270
P G + PPP A P APP A
Sbjct: 917 GPEGGAAASPPPDAELAACHPAAWSRGPAPPLA 949
Score = 52.8 bits (125), Expect = 4e-07
Identities = 90/341 (26%), Positives = 113/341 (33%), Gaps = 73/341 (21%)
Query: 2 LLRPRRPPPLAPPAPPSPAS-------------PDPE-------PRTPGDAPGTPPRRPA 41
LL PR P PP P +PA+ P E P AP P R A
Sbjct: 24 LLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTRSA 83
Query: 42 SPSALGELGLPVSPGSAQRTPWSARETELLLGTLLQPAVWRALLLDRRQALPTYRRVSAA 101
S+ P + G +R P A+ T G + P RA R P ++
Sbjct: 84 GTSSRNPASRPPASGRGERAP-PAKNTSP--GPVSSPG--RASGTTRPG--PLGQKGLRI 136
Query: 102 LAQQQVRRTPA-QCRRRYKFLKDKFREAHGQPPG-PFDEQIRKLMGLLGDNGRKRPR--- 156
A++ V R A + +R R+ G PG P R+ + G RP
Sbjct: 137 SAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSA 196
Query: 157 ---------RRSPGSGRPQRARRPVPNAHAPAPSEPDATPLPTARDRDADPTWTLRFSPS 207
R+S S P P A PS P +R + T + S
Sbjct: 197 RPRPPTEGPRKSVSSASEHSTTEPSPAARR-RPSAGGGLQRPASRSLSSSATPLSSPARS 255
Query: 208 PPKSADASPAPGSPPAPAPTALATCIP-------EDRAPVRGP--GSP------------ 246
P + AP P P P L P +D AP GP SP
Sbjct: 256 GPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSGTKAR 315
Query: 247 --PPP-------PAREDPDSPPGRPEDCAPP-PAAPPSLNT 277
PPP PA P P P APP P+APPSL T
Sbjct: 316 PVPPPDNAATPLPATLPPSPPLATPLPLAPPSPSAPPSLQT 356
Score = 48.1 bits (113), Expect = 1e-05
Identities = 74/282 (26%), Positives = 90/282 (31%), Gaps = 29/282 (10%)
Query: 1 MLLRPRRPPPLAPPAPPSPASPDPEPRTPG-------DAPGTPPRRPASPSALGELGLPV 53
+ L P + PP P +PP P P+ P AP +P P SP P
Sbjct: 625 LALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSP---PPSPPVQAPFSPPA 681
Query: 54 SPG-SAQRTPWSARETELLLGTL-LQPAVWRALLLDRRQALPTYRRVSAALAQQQVRRTP 111
SP S TP S L L + P+ + + P A QV +P
Sbjct: 682 SPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQVPPSP 741
Query: 112 AQCRRRYKFLKDKFREAHGQPPGPFDEQIRKLMGLLGDNGRKRPRRRSPGSGRPQRARRP 171
R P L K P + P P P
Sbjct: 742 PASPPMSPSATPPPRVPPLLAAPPLQVPPSPPASLPMSPLAKPPPQAPPALATPPLQALP 801
Query: 172 VPNAHAPA----------PSEPDATPLPTARDRDADPTWTLRFSPSPPKSADASPAPGSP 221
P A P P P ATP P A A P L+ PSPP S AP P
Sbjct: 802 SPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAP--LLQVPPSPPASPTLQ-APRRP 858
Query: 222 PAPAPTALATCIPEDRAPVRGPGSPPPPPAREDPDSPPGRPE 263
P P P T + R + PPPPP+R P S P+
Sbjct: 859 PTPGPD---TSVSGPRLTLALAPGPPPPPSR-SPSSTLSGPD 896
Score = 45.8 bits (107), Expect = 5e-05
Identities = 78/310 (25%), Positives = 109/310 (35%), Gaps = 73/310 (23%)
Query: 9 PPLAPP---APPSPASPDPEPRTPGDAPGTPPRRPASPSALGELGLPVSPGSAQRTPWSA 65
PPLA P APPSP++P P +T P TPP + +P S P A
Sbjct: 335 PPLATPLPLAPPSPSAP-PSLQTLPSPPATPPSQ--------------APPSMTTPPMQA 379
Query: 66 RETELLLGTLLQPAVWRALLLDRRQALPTYRRVSAALAQQQVRRTPAQCRRRYKFLKDKF 125
+ L T+ V +L QA P+ +S+ A + Q + + +
Sbjct: 380 PPS---LQTIPPIQVPHSLTSPSLQAPPSPLALSSLQATTSLGSPTLQATHSFLTMSPRQ 436
Query: 126 REAHGQPPGPFDEQIRKLMGLLGDNGRKRPRRRSPGSGRPQR-----ARRPVPNAHAPAP 180
+A P RP P S Q A P+ + +PA
Sbjct: 437 TQASLTSPS-------------------RPASTPPDSPPLQAPLSLPASPPLQTSLSPAV 477
Query: 181 SEPDATPLPT---------ARDRDADPTWTLRFSPSPPKSADASPAPGSPPAPAPTALAT 231
S P ++PL A P +L P +S+ A P+ +PPA T
Sbjct: 478 S-PLSSPLTIHPLQALSSLASHSPQAPLSSLIMPPLETQSSLAPPSLQTPPASLTTPPLE 536
Query: 232 CIPEDRAP-------------VRGPGSPPPPPAREDPDS----PPGRPEDCA-PPPAAPP 273
+P P + P P P P + P PP P A PPP APP
Sbjct: 537 NLPSLAPPPLQTASAPLTTPHLETPPCPAPCPLQAPPSPLTTPPPETPSSIATPPPQAPP 596
Query: 274 SLNTALLQTL 283
+L + LQ L
Sbjct: 597 ALASPPLQGL 606
Score = 42.4 bits (98), Expect = 6e-04
Identities = 77/274 (28%), Positives = 90/274 (32%), Gaps = 78/274 (28%)
Query: 7 RPPPLAPPA---PPSPASPDPEPRTPGDAPGTPPRRPASPSALGELGLPVSPGSAQRTPW 63
+PPP APPA PP A P P PG AP SPSA LP+SP TP
Sbjct: 783 KPPPQAPPALATPPLQALPSPPASFPGQAP-------FSPSA----SLPMSP---LATP- 827
Query: 64 SARETELLLGTLLQ----PAVWRALLLDRRQALP------TYRRVSAALAQQQVRRTPAQ 113
+ +L LLQ P L RR P + R++ ALA
Sbjct: 828 PPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAP--------- 878
Query: 114 CRRRYKFLKDKFREAHGQPPGPFDEQIRKLMG--LLGDNGRKRPRRRSPGSGRPQRAR-- 169
G PP P L G L G + S + P+ R
Sbjct: 879 ----------------GPPPPPSRSPSSTLSGPDLAGHS--------SSATSTPEELRGY 914
Query: 170 RPVPNAHAPAPSEPDATPL---PTARDRDADPTWTLRFSPSPPKSADASPAPGSPPAPAP 226
P A A PDA P A R P R +P P + PGS
Sbjct: 915 DSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPATGPGS-----A 969
Query: 227 TALATCIPEDRAPVRGPGSPPPPPAREDPDSPPG 260
L T + GP S P P DP PG
Sbjct: 970 DGLCTIYETE-----GPESATPAPGALDPGPSPG 998
Score = 33.1 bits (74), Expect = 0.37
Identities = 30/94 (31%), Positives = 40/94 (42%), Gaps = 14/94 (14%)
Query: 5 PRRPPPLAPPAPPSPA--------SPDPEPRTPGDAPGTPPRRPASPSALGELGLPVSPG 56
P P P P P A + PE TP APG P+ ++ G+ G
Sbjct: 954 PGAPLPWPPATGPGSADGLCTIYETEGPESATP--APGALDPGPSPGTSGGKAAAGAGAG 1011
Query: 57 SAQRTPWSARETELLLGTL----LQPAVWRALLL 86
++ R+P AR EL LG L +Q + R LLL
Sbjct: 1012 ASSRSPKQARLGELPLGALQASVVQHLLSRTLLL 1045
Score = 32.0 bits (71), Expect = 0.82
Identities = 32/84 (38%), Positives = 35/84 (41%), Gaps = 22/84 (26%)
Query: 5 PRRPPPLAPP---APPSP-ASPDPE----PRTPGD-------------APGTPPRRPASP 43
P+ PP LA P PPSP ASP + P TPG APG PP SP
Sbjct: 829 PQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSP 888
Query: 44 SA-LGELGLPVSPGSAQRTPWSAR 66
S+ L L SA TP R
Sbjct: 889 SSTLSGPDLAGHSSSATSTPEELR 912
>gi|7662046 myeloid/lymphoid or mixed-lineage leukemia 4 [Homo
sapiens]
Length = 2715
Score = 67.8 bits (164), Expect = 1e-11
Identities = 80/303 (26%), Positives = 107/303 (35%), Gaps = 54/303 (17%)
Query: 5 PRRPPPLAPPA---PPSPASPDPEPRTPGDAPGTPPRRPASPSALGELGLPVSPGSAQR- 60
P PPPL PP+ PP P P P +P P PP P + E PV P + R
Sbjct: 411 PSPPPPLPPPSTSPPPPLCPPPPPPVSPPPLPSPPP--PPAQEEQEESPPPVVPATCSRK 468
Query: 61 ------TPWSARETELLL----GTLLQPAVWRALLLDRRQALPTYRRVSAALAQQQVRR- 109
TP E E GT + PT S + +R+
Sbjct: 469 RGRPPLTPSQRAEREAARAGPEGTSPPTPTPSTATGGPPEDSPTVAPKSTTFLKN-IRQF 527
Query: 110 -TPAQCRRRYKFLKDKFREAHGQPPGPFDEQIRKLMGLLGDNGRKRPRRRSPGSGRPQRA 168
P R + +K R PP P ++ ++ R P + P
Sbjct: 528 IMPVVSARSSRVIKTPRRFMDEDPPKPPKVEVSPVL-------------RPPITTSPPVP 574
Query: 169 RRPVPNAHAPAPSEPDATPLPTARDRDA---DPT--WT--LRFSPSPPKSADASPAPGSP 221
+ P P P P +TP+P R + +PT WT R P PP + PAP P
Sbjct: 575 QEPAPVPSPPRAPTPPSTPVPLPEKRRSILREPTFRWTSLTRELPPPPPAPPPPPAPSPP 634
Query: 222 PAPAPTALATCIPEDRAPVRGPG-----------SPPP--PPAREDPDSPPGRPEDCAPP 268
PAPA ++ + RAP P +PPP P +P+ PP P
Sbjct: 635 PAPATSSRRPLLL--RAPQFTPSEAHLKIYESVLTPPPLGAPEAPEPEPPPADDSPAEPE 692
Query: 269 PAA 271
P A
Sbjct: 693 PRA 695
Score = 54.7 bits (130), Expect = 1e-07
Identities = 75/306 (24%), Positives = 98/306 (32%), Gaps = 95/306 (31%)
Query: 8 PPPLAPPAPPSPASPDPEPRTPGDAPGTPPRRPASPSALGELGLPVSPGSAQRTPWSARE 67
PPPL PPAP SP P P P T P PP P PVSP P +
Sbjct: 403 PPPLTPPAP-SPPPPLPPPSTSPPPPLCPPPPP-----------PVSPPPLPSPPPPPAQ 450
Query: 68 TELLLGTLLQPAVWRALLLDRRQALPTYRRVSAALAQQQVRRTPAQCRRRYKFLKDKFRE 127
E + ++ P PA C R+
Sbjct: 451 EE------------------QEESPPPV--------------VPATCSRK---------- 468
Query: 128 AHGQPPGPFDEQIRKLMGLLGDNGRK--RPRRRSPGSGRPQRARRPVPNAHA-------- 177
G+PP ++ + G G P + G P+ + P +
Sbjct: 469 -RGRPPLTPSQRAEREAARAGPEGTSPPTPTPSTATGGPPEDSPTVAPKSTTFLKNIRQF 527
Query: 178 --PAPSEPDATPLPTAR---DRDADPTWTLRFSP--------SPPKSADASPAPGSPPAP 224
P S + + T R D D + SP SPP + +P P P AP
Sbjct: 528 IMPVVSARSSRVIKTPRRFMDEDPPKPPKVEVSPVLRPPITTSPPVPQEPAPVPSPPRAP 587
Query: 225 APTALATCIPEDRAPV-RGP---------GSPPPPPAREDPDSPPGRPEDCAPPPAAPPS 274
P + +PE R + R P PPPPPA P +P +PPPA S
Sbjct: 588 TPPSTPVPLPEKRRSILREPTFRWTSLTRELPPPPPAPPPPPAP-------SPPPAPATS 640
Query: 275 LNTALL 280
LL
Sbjct: 641 SRRPLL 646
Score = 43.9 bits (102), Expect = 2e-04
Identities = 33/110 (30%), Positives = 41/110 (37%), Gaps = 35/110 (31%)
Query: 166 QRARRPVPNAHAPAPSEPDATPLPTARDRDADPTWTLRFSPSPPKSADASPAPGSPPAPA 225
+ A+ P P PAPS P P P+ SP PP P P P +P
Sbjct: 397 EEAKLPPPPLTPPAPSPPPPLPPPST-------------SPPPP----LCPPPPPPVSPP 439
Query: 226 PTALATCIPEDRAPVRGPGSPPPPPAREDPDS--PPGRPEDCAPPPAAPP 273
P SPPPPPA+E+ + PP P C+ PP
Sbjct: 440 PLP----------------SPPPPPAQEEQEESPPPVVPATCSRKRGRPP 473
Score = 43.9 bits (102), Expect = 2e-04
Identities = 28/82 (34%), Positives = 35/82 (42%), Gaps = 9/82 (10%)
Query: 176 HAPAPSEPDATPLPTARDRDADPTWTLRFSPSPPKSADASPAPGSPP---APAPTALATC 232
H P +PD P P R R P +P PP S ASP + P P PT++ T
Sbjct: 1897 HIPTVGDPDF-PAPPRRSRRPSP-----LAPRPPPSRWASPPLKTSPQLRVPPPTSVVTA 1950
Query: 233 IPEDRAPVRGPGSPPPPPARED 254
+ + PG P PP ED
Sbjct: 1951 LTPTSGELAPPGPAPSPPPPED 1972
Score = 43.9 bits (102), Expect = 2e-04
Identities = 82/332 (24%), Positives = 107/332 (32%), Gaps = 73/332 (21%)
Query: 4 RPRRPPPLAPPAPPS-----PASPDPEPRTPGDAPGTPPRRPASPSALGELGLP---VSP 55
R RRP PLAP PPS P P+ R P P T +P++ GEL P SP
Sbjct: 1912 RSRRPSPLAPRPPPSRWASPPLKTSPQLRVP---PPTSVVTALTPTS-GELAPPGPAPSP 1967
Query: 56 GSAQRTPWSARETELLLGTLLQPAVWRALLLDRRQALPTYRRVSAALAQQQVRRTPAQCR 115
+ + E++ G + A LL P + AA A P
Sbjct: 1968 PPPEDLGPDFEDMEVVSGLSAADLDFAASLLGTE---PFQEEIVAAGAMGSSHGGPGDSS 2024
Query: 116 R-------RYKFLKDKFREAHGQPPG--PFDEQIRKLMGLL-GDNGRKRPRRRSPGSGRP 165
RY A G P P +I +L G+ G + ++ G G P
Sbjct: 2025 EEESSPTSRYIHFPVTVVSAPGLAPSATPGAPRIEQLDGVDDGTDSEAEAVQQPRGQGTP 2084
Query: 166 ----------------QRARRPV----------------PNAHAPAPSEPDATPLPTARD 193
RAR P P P E P P +
Sbjct: 2085 PSGPGVVRAGVLGAAGDRARPPEDLPSEIVDFVLKNLGGPGDGGAGPREESLPPAPPLAN 2144
Query: 194 RD----------ADPTWTLRFSPSPP--KSADASPAPGSP-PAPAPTALATCIPEDRAPV 240
ADPT T + P P + PAP P PA + L + + +
Sbjct: 2145 GSQPSQGLTASPADPTRTFAWLPGAPGVRVLSLGPAPEPPKPATSKIILVNKLGQVFVKM 2204
Query: 241 RGPGSPPPPPAREDPDSP---PGRPEDCAPPP 269
G G P PPP ++ P P P P PP
Sbjct: 2205 AGEGEPVPPPVKQPPLPPTISPTAPTSWTLPP 2236
Score = 41.2 bits (95), Expect = 0.001
Identities = 39/133 (29%), Positives = 51/133 (38%), Gaps = 13/133 (9%)
Query: 163 GRPQRARRPVPNAHAPAPSEPDATPLPTARDRDADPTWTLRFSPSPPKSADAS----PAP 218
G P+R P+ N P + + P P R +SPS S P+P
Sbjct: 1830 GAPER-HSPIQNLDPPLRPDSGSAPPPAPRSFSGARIKVPNYSPSRRPLGGVSFGPLPSP 1888
Query: 219 GSPPAPAPTALATCIPEDRAPVR-----GPGSPPPPPAREDPDSPPGRPEDCAPPPAAPP 273
GSP + P+ AP R P +P PPP+R P+ PPP
Sbjct: 1889 GSPSSLTHHIPTVGDPDFPAPPRRSRRPSPLAPRPPPSRWASPPLKTSPQLRVPPPT--- 1945
Query: 274 SLNTALLQTLGHL 286
S+ TAL T G L
Sbjct: 1946 SVVTALTPTSGEL 1958
Score = 38.5 bits (88), Expect = 0.009
Identities = 27/75 (36%), Positives = 35/75 (46%), Gaps = 9/75 (12%)
Query: 165 PQRARRPVPNAHAPAPSEPDATPLPTARDRDADPTWTLRFSPSPPKSADASPAPGSPPAP 224
P+R+RRP P A P PS + PL T+ P T + P S + +P PG P+P
Sbjct: 1910 PRRSRRPSPLAPRPPPSRWASPPLKTSPQLRVPPP-TSVVTALTPTSGELAP-PGPAPSP 1967
Query: 225 APTALATCIPEDRAP 239
P PED P
Sbjct: 1968 PP-------PEDLGP 1975
Score = 34.7 bits (78), Expect = 0.13
Identities = 17/32 (53%), Positives = 18/32 (56%), Gaps = 1/32 (3%)
Query: 2 LLRPRRPPPLAPPAPPSPASPDPEPRTPGDAP 33
L R PPP APP PP+P SP P P T P
Sbjct: 614 LTRELPPPPPAPPPPPAP-SPPPAPATSSRRP 644
Score = 32.3 bits (72), Expect = 0.63
Identities = 15/29 (51%), Positives = 17/29 (58%)
Query: 15 APPSPASPDPEPRTPGDAPGTPPRRPASP 43
AP +P S EP TP + G PP RPA P
Sbjct: 202 APQAPRSRACEPSTPRRSRGRPPGRPAGP 230
Score = 32.0 bits (71), Expect = 0.82
Identities = 28/83 (33%), Positives = 33/83 (39%), Gaps = 9/83 (10%)
Query: 5 PRRPPPLAPPAPPSPASPDPEP--RT-----PGDAP--GTPPRRPASPSALGELGLPVSP 55
P P P PPA SPA P+P RT P AP TP + SP L
Sbjct: 674 PEAPEPEPPPADDSPAEPEPRAVGRTNHLSLPRFAPVVTTPVKAEVSPHGAPALSNGPQT 733
Query: 56 GSAQRTPWSARETELLLGTLLQP 78
+ P A +T+LL L P
Sbjct: 734 QAQLLQPLQALQTQLLPQALPPP 756
Score = 31.2 bits (69), Expect = 1.4
Identities = 19/61 (31%), Positives = 27/61 (44%), Gaps = 8/61 (13%)
Query: 11 LAPPAPPSPASPDPEPRTPGDAPGTPPRRPASPSALGELGLP------VSPGSAQRTPWS 64
L PP +P +P+PEP D+P P P + L LP +P A+ +P
Sbjct: 666 LTPPPLGAPEAPEPEPPPADDSPAEP--EPRAVGRTNHLSLPRFAPVVTTPVKAEVSPHG 723
Query: 65 A 65
A
Sbjct: 724 A 724
Score = 30.8 bits (68), Expect = 1.8
Identities = 23/82 (28%), Positives = 37/82 (45%), Gaps = 1/82 (1%)
Query: 200 WTLRFSPSPPKSADASPAPGSPPAPAPTALATCIPEDRAPVRGPGSPPPPPAREDPDSPP 259
W R P+ ++A+ + PAP+ P V PG+P ++ D PP
Sbjct: 1786 WGPREEPAHLEAAEENQTIVHSPAPSSEPPGGEDPPLDTDVLVPGAPERHSPIQNLD-PP 1844
Query: 260 GRPEDCAPPPAAPPSLNTALLQ 281
RP+ + PP AP S + A ++
Sbjct: 1845 LRPDSGSAPPPAPRSFSGARIK 1866
Score = 28.9 bits (63), Expect = 6.9
Identities = 22/62 (35%), Positives = 28/62 (45%), Gaps = 9/62 (14%)
Query: 5 PRRPPPLA----PPAPPSPASPDPEPRTPGDA----PG-TPPRRPASPSALGELGLPVSP 55
P R P+ P P S ++P P PR+ A P +P RRP + G L P SP
Sbjct: 1832 PERHSPIQNLDPPLRPDSGSAPPPAPRSFSGARIKVPNYSPSRRPLGGVSFGPLPSPGSP 1891
Query: 56 GS 57
S
Sbjct: 1892 SS 1893
Score = 28.5 bits (62), Expect = 9.1
Identities = 26/96 (27%), Positives = 29/96 (30%), Gaps = 25/96 (26%)
Query: 178 PAPSEPDATPLPTARDRDADPTWTLRFSP------------------SPPKSADASPAPG 219
P P PLP A +WTL P PP + S P
Sbjct: 2210 PVPPPVKQPPLPPTISPTAPTSWTLPPGPLLGVLPVVGVVRPAPPPPPPPLTLVLSSGPA 2269
Query: 220 SPPAPAPTALATCIPEDRAPVRGPGSPPPPPAREDP 255
SPP A I R SPP PP + P
Sbjct: 2270 SPPRQA-------IRVKRVSTFSGRSPPAPPPYKAP 2298
>gi|189181724 proteoglycan 4 isoform D [Homo sapiens]
Length = 1270
Score = 65.1 bits (157), Expect = 9e-11
Identities = 70/284 (24%), Positives = 95/284 (33%), Gaps = 55/284 (19%)
Query: 2 LLRPRRPPPLAPPAPPSPASPDPEPRTPGDAPGTPPRRPASPSALGELGLPVSPGSAQRT 61
L P+ P P P P S +P P T AP T P+ PA P + SA T
Sbjct: 210 LTTPKEPTPTTPKEPASTTPKEPTPTTIKSAP-TTPKEPA----------PTTTKSAPTT 258
Query: 62 PWSARETELLLGTLLQPAVWRALLLDRRQALPTYRRVSAALAQQQVRRTPAQCRRRYKFL 121
P T T +PA ++ PT + A + TP +
Sbjct: 259 PKEPAPT-----TTKEPAPTTP-----KEPAPTTTKEPAPTTTKSAPTTPKE-------- 300
Query: 122 KDKFREAHGQPPGPFDEQIRKLMGLLGDNGRKRPRRRSPGSGRPQRARRPVPNAHAPAPS 181
A P P K P +P P + P P PAP+
Sbjct: 301 -----PAPTTPKKP------------APTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPT 343
Query: 182 EPDATPLPTARDRDA-----DPTWTLRFSPSPPKSADASPAPGSPPAPAPTALATCIPED 236
P P PTA + A +P T P+P + + SP PAP T A ++
Sbjct: 344 TPKE-PAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKE 402
Query: 237 RAPVR---GPGSPPPPPAREDPDSPPGRPEDCAPPPAAPPSLNT 277
AP P +P P + P P++ AP P+ T
Sbjct: 403 PAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTT 446
Score = 55.5 bits (132), Expect = 7e-08
Identities = 76/310 (24%), Positives = 111/310 (35%), Gaps = 48/310 (15%)
Query: 5 PRRPPPLAP--PAP-----PSPASP-DPEPRTPGDAPGTPPRRPASPSALGELGLPVSPG 56
P+ P P P PAP PSP +P +P P T AP T + PA + P P
Sbjct: 361 PKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAP-TTTKEPAPTTTKSAPTTPKEPS 419
Query: 57 -SAQRTPWSARETELLLGTLLQPAVWR----ALLLDRRQALPTYRRVSAALAQQQVRRTP 111
+ + P E T +PA A + A T ++ + ++ TP
Sbjct: 420 PTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTP 479
Query: 112 AQC-----RRRYKFLKDKFREAHGQPPGPFDEQIRKLMGLLGDNGRKRPRRRSPGSGRPQ 166
+ ++ +K + P P + L + P +P P
Sbjct: 480 KETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEE------LAPTTPEEPTPTTPEEPAPT 533
Query: 167 RARRPVPNA-HAPAPSEPDATPLPTARDRDADPTWTLRFSPSPPKSADAS----PAPGSP 221
+ PN PAP+ P P PT ++ PT +P+ PK + PAP +P
Sbjct: 534 TPKAAAPNTPKEPAPTTP-KEPAPTT-PKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTP 591
Query: 222 PAPAPTALA----------TCIPEDRAPVRGPGSPPPPPAREDPDSP----PGRPEDCAP 267
PAP LA TC + AP G+ P P P +P P P+ AP
Sbjct: 592 KKPAPKELAPTTTKEPTSTTC--DKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAP 649
Query: 268 PPAAPPSLNT 277
P+ T
Sbjct: 650 TTLKEPAPTT 659
Score = 53.9 bits (128), Expect = 2e-07
Identities = 75/303 (24%), Positives = 97/303 (32%), Gaps = 58/303 (19%)
Query: 5 PRRPPPLAPPAP--PSPASPD-PEPRTPGDAPGTPPRRPA-------SPSALGELGLPVS 54
P P LAP P P+P +P+ P P TP A P+ PA +P+ E
Sbjct: 508 PTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTP 567
Query: 55 PGSAQRTPWSARETELLLGTLLQPAVWRALLLDRRQALPTYRRVSAALAQQQVRRTPAQC 114
+A TP T TL +PA ++ PT + T C
Sbjct: 568 KETAPTTPKGTAPT-----TLKEPAPTTPKKPAPKELAPTTTK----------EPTSTTC 612
Query: 115 RRRYKFLKDKFREAHGQPPGPFDEQIRKLMGLLGDNGRKRPRRRSPGSGRPQRARRPVPN 174
+ + P P K P +P P + P P
Sbjct: 613 DKPAPTTPKGTAPTTPKEPAPTTP--------------KEPAPTTPKGTAPTTLKEPAPT 658
Query: 175 A-HAPAPSE--PDATPLPTARDRDAD-PTWTLRFSPSPPK----SADASPAPGSPPAPAP 226
PAP E P T PT+ D PT +P+ PK + PAP +P P P
Sbjct: 659 TPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPP 718
Query: 227 TALATCIPED-RAPVRGPGSP----------PPPPAREDPDSPPGRPEDCAPPPAAPPSL 275
T P + P SP P P A E+ PG P P P
Sbjct: 719 TTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMT 778
Query: 276 NTA 278
TA
Sbjct: 779 TTA 781
Score = 52.0 bits (123), Expect = 8e-07
Identities = 72/295 (24%), Positives = 102/295 (34%), Gaps = 56/295 (18%)
Query: 3 LRPRRPPPLAPPAPPSPASPDPE---PRTPGDAPGTPPRRPA--SPSALGELGLPVSPGS 57
L P P LAP P PA PE P TP + T P PA +P A P P
Sbjct: 490 LTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAP-NTPKEP-- 546
Query: 58 AQRTPWSARETELLLGTLLQPAVWRALLLDRRQALPTYRRVSAALAQQQVRRTPAQCRRR 117
A TP T T +PA ++ PT + +A ++ PA +
Sbjct: 547 APTTPKEPAPT-----TPKEPAP-----TTPKETAPTTPKGTAPTTLKE----PAPTTPK 592
Query: 118 YKFLKDKFREAHGQPPGPFDEQIRKLMGLLGDNGRKRPRRRSPGSGRPQRARRPVPNA-H 176
K+ +P + +P +P P + P P
Sbjct: 593 KPAPKELAPTTTKEPTSTTCD---------------KPAPTTPKGTAPTTPKEPAPTTPK 637
Query: 177 APAPSEPDAT-------PLPTARDRDADPTWTLRFSPSPPKSADASPAPGSPPAPAPTA- 228
PAP+ P T P PT + A + P + PAP +P APT
Sbjct: 638 EPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTP 697
Query: 229 --LATCIPEDRAPVRGPGSPPP-------PPAREDPDSPPGRPEDCAPPPAAPPS 274
A P+ AP P +PPP P ++P + P++ P +A P+
Sbjct: 698 KEPAPTTPKKPAPTT-PETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPT 751
Score = 49.7 bits (117), Expect = 4e-06
Identities = 34/129 (26%), Positives = 47/129 (36%), Gaps = 4/129 (3%)
Query: 153 KRPRRRSPGSGRPQRARRPVPNAHAPAPS---EPDATPLPTARDRDADPTWTLRFSPSPP 209
K P +P + P P AP+ EP T +A +P T P+P
Sbjct: 214 KEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPT 273
Query: 210 KSADASPAPGSPPAPAPTALATCIPEDRAPVRGPGSPPPPPAREDPDSPPGRPEDCAPPP 269
+ +P PAP T A P++ AP P P P +E + P P P
Sbjct: 274 TPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTT-PKKPAPTTPKEPAPTTPKEPTPTTPKE 332
Query: 270 AAPPSLNTA 278
AP + A
Sbjct: 333 PAPTTKEPA 341
Score = 47.8 bits (112), Expect = 1e-05
Identities = 39/139 (28%), Positives = 51/139 (36%), Gaps = 23/139 (16%)
Query: 153 KRPRRRSPGSGRPQRARRPVPNAHAPAPSEPDATPLPTARDRDA-------------DPT 199
K P +P P + P P AP+ P P PT + A +PT
Sbjct: 268 KEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKE-PAPTTPKKPAPTTPKEPAPTTPKEPT 326
Query: 200 WTLRFSPSPPKSADASPAPGSPPAPAPTALATCIPEDRAPVRGPGSPPPPPAREDPDSPP 259
T P+P PAP +P PAPTA P+ AP P P P +E +
Sbjct: 327 PTTPKEPAP---TTKEPAPTTPKEPAPTA-----PKKPAPTT-PKEPAPTTPKEPAPTTT 377
Query: 260 GRPEDCAPPPAAPPSLNTA 278
P P AP + +A
Sbjct: 378 KEPSPTTPKEPAPTTTKSA 396
Score = 38.1 bits (87), Expect = 0.011
Identities = 38/127 (29%), Positives = 51/127 (40%), Gaps = 20/127 (15%)
Query: 170 RPVPNAH----APA---PSEP-DATPLPTARDRDADPT-WTLRFSPSPPKS---ADASPA 217
+P P A PA P EP TP A +PT T++ +P+ PK A
Sbjct: 196 KPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSA 255
Query: 218 PGSPPAPAPTAL---ATCIPEDRAPVRGPGSPPPPPAREDPDSP----PGRPEDCAPPPA 270
P +P PAPT A P++ AP P P + P +P P P+ AP
Sbjct: 256 PTTPKEPAPTTTKEPAPTTPKEPAPTT-TKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTP 314
Query: 271 APPSLNT 277
P+ T
Sbjct: 315 KEPAPTT 321
Score = 37.7 bits (86), Expect = 0.015
Identities = 27/98 (27%), Positives = 38/98 (38%), Gaps = 7/98 (7%)
Query: 185 ATPLPTARDRDADPTWTLRFSPSPPKSADASPAPGSPPAPAPTAL--ATCIPEDRAPV-- 240
A P P A P T P+P + PA +P P PT + A P++ AP
Sbjct: 195 AKPTPKAETTTKGPALTTPKEPTP--TTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTT 252
Query: 241 -RGPGSPPPPPAREDPDSPPGRPEDCAPPPAAPPSLNT 277
P +P P + P P++ AP P+ T
Sbjct: 253 KSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTT 290
>gi|189181722 proteoglycan 4 isoform C [Homo sapiens]
Length = 1311
Score = 65.1 bits (157), Expect = 9e-11
Identities = 70/284 (24%), Positives = 95/284 (33%), Gaps = 55/284 (19%)
Query: 2 LLRPRRPPPLAPPAPPSPASPDPEPRTPGDAPGTPPRRPASPSALGELGLPVSPGSAQRT 61
L P+ P P P P S +P P T AP T P+ PA P + SA T
Sbjct: 251 LTTPKEPTPTTPKEPASTTPKEPTPTTIKSAP-TTPKEPA----------PTTTKSAPTT 299
Query: 62 PWSARETELLLGTLLQPAVWRALLLDRRQALPTYRRVSAALAQQQVRRTPAQCRRRYKFL 121
P T T +PA ++ PT + A + TP +
Sbjct: 300 PKEPAPT-----TTKEPAPTTP-----KEPAPTTTKEPAPTTTKSAPTTPKE-------- 341
Query: 122 KDKFREAHGQPPGPFDEQIRKLMGLLGDNGRKRPRRRSPGSGRPQRARRPVPNAHAPAPS 181
A P P K P +P P + P P PAP+
Sbjct: 342 -----PAPTTPKKP------------APTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPT 384
Query: 182 EPDATPLPTARDRDA-----DPTWTLRFSPSPPKSADASPAPGSPPAPAPTALATCIPED 236
P P PTA + A +P T P+P + + SP PAP T A ++
Sbjct: 385 TPKE-PAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKE 443
Query: 237 RAPVR---GPGSPPPPPAREDPDSPPGRPEDCAPPPAAPPSLNT 277
AP P +P P + P P++ AP P+ T
Sbjct: 444 PAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTT 487
Score = 55.5 bits (132), Expect = 7e-08
Identities = 76/310 (24%), Positives = 111/310 (35%), Gaps = 48/310 (15%)
Query: 5 PRRPPPLAP--PAP-----PSPASP-DPEPRTPGDAPGTPPRRPASPSALGELGLPVSPG 56
P+ P P P PAP PSP +P +P P T AP T + PA + P P
Sbjct: 402 PKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAP-TTTKEPAPTTTKSAPTTPKEPS 460
Query: 57 -SAQRTPWSARETELLLGTLLQPAVWR----ALLLDRRQALPTYRRVSAALAQQQVRRTP 111
+ + P E T +PA A + A T ++ + ++ TP
Sbjct: 461 PTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTP 520
Query: 112 AQC-----RRRYKFLKDKFREAHGQPPGPFDEQIRKLMGLLGDNGRKRPRRRSPGSGRPQ 166
+ ++ +K + P P + L + P +P P
Sbjct: 521 KETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEE------LAPTTPEEPTPTTPEEPAPT 574
Query: 167 RARRPVPNA-HAPAPSEPDATPLPTARDRDADPTWTLRFSPSPPKSADAS----PAPGSP 221
+ PN PAP+ P P PT ++ PT +P+ PK + PAP +P
Sbjct: 575 TPKAAAPNTPKEPAPTTP-KEPAPTT-PKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTP 632
Query: 222 PAPAPTALA----------TCIPEDRAPVRGPGSPPPPPAREDPDSP----PGRPEDCAP 267
PAP LA TC + AP G+ P P P +P P P+ AP
Sbjct: 633 KKPAPKELAPTTTKEPTSTTC--DKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAP 690
Query: 268 PPAAPPSLNT 277
P+ T
Sbjct: 691 TTLKEPAPTT 700
Score = 53.9 bits (128), Expect = 2e-07
Identities = 75/303 (24%), Positives = 97/303 (32%), Gaps = 58/303 (19%)
Query: 5 PRRPPPLAPPAP--PSPASPD-PEPRTPGDAPGTPPRRPA-------SPSALGELGLPVS 54
P P LAP P P+P +P+ P P TP A P+ PA +P+ E
Sbjct: 549 PTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTP 608
Query: 55 PGSAQRTPWSARETELLLGTLLQPAVWRALLLDRRQALPTYRRVSAALAQQQVRRTPAQC 114
+A TP T TL +PA ++ PT + T C
Sbjct: 609 KETAPTTPKGTAPT-----TLKEPAPTTPKKPAPKELAPTTTK----------EPTSTTC 653
Query: 115 RRRYKFLKDKFREAHGQPPGPFDEQIRKLMGLLGDNGRKRPRRRSPGSGRPQRARRPVPN 174
+ + P P K P +P P + P P
Sbjct: 654 DKPAPTTPKGTAPTTPKEPAPTTP--------------KEPAPTTPKGTAPTTLKEPAPT 699
Query: 175 A-HAPAPSE--PDATPLPTARDRDAD-PTWTLRFSPSPPK----SADASPAPGSPPAPAP 226
PAP E P T PT+ D PT +P+ PK + PAP +P P P
Sbjct: 700 TPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPP 759
Query: 227 TALATCIPED-RAPVRGPGSP----------PPPPAREDPDSPPGRPEDCAPPPAAPPSL 275
T P + P SP P P A E+ PG P P P
Sbjct: 760 TTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMT 819
Query: 276 NTA 278
TA
Sbjct: 820 TTA 822
Score = 52.0 bits (123), Expect = 8e-07
Identities = 72/295 (24%), Positives = 102/295 (34%), Gaps = 56/295 (18%)
Query: 3 LRPRRPPPLAPPAPPSPASPDPE---PRTPGDAPGTPPRRPA--SPSALGELGLPVSPGS 57
L P P LAP P PA PE P TP + T P PA +P A P P
Sbjct: 531 LTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAP-NTPKEP-- 587
Query: 58 AQRTPWSARETELLLGTLLQPAVWRALLLDRRQALPTYRRVSAALAQQQVRRTPAQCRRR 117
A TP T T +PA ++ PT + +A ++ PA +
Sbjct: 588 APTTPKEPAPT-----TPKEPAP-----TTPKETAPTTPKGTAPTTLKE----PAPTTPK 633
Query: 118 YKFLKDKFREAHGQPPGPFDEQIRKLMGLLGDNGRKRPRRRSPGSGRPQRARRPVPNA-H 176
K+ +P + +P +P P + P P
Sbjct: 634 KPAPKELAPTTTKEPTSTTCD---------------KPAPTTPKGTAPTTPKEPAPTTPK 678
Query: 177 APAPSEPDAT-------PLPTARDRDADPTWTLRFSPSPPKSADASPAPGSPPAPAPTA- 228
PAP+ P T P PT + A + P + PAP +P APT
Sbjct: 679 EPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTP 738
Query: 229 --LATCIPEDRAPVRGPGSPPP-------PPAREDPDSPPGRPEDCAPPPAAPPS 274
A P+ AP P +PPP P ++P + P++ P +A P+
Sbjct: 739 KEPAPTTPKKPAPTT-PETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPT 792
Score = 49.7 bits (117), Expect = 4e-06
Identities = 34/129 (26%), Positives = 47/129 (36%), Gaps = 4/129 (3%)
Query: 153 KRPRRRSPGSGRPQRARRPVPNAHAPAPS---EPDATPLPTARDRDADPTWTLRFSPSPP 209
K P +P + P P AP+ EP T +A +P T P+P
Sbjct: 255 KEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPT 314
Query: 210 KSADASPAPGSPPAPAPTALATCIPEDRAPVRGPGSPPPPPAREDPDSPPGRPEDCAPPP 269
+ +P PAP T A P++ AP P P P +E + P P P
Sbjct: 315 TPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTT-PKKPAPTTPKEPAPTTPKEPTPTTPKE 373
Query: 270 AAPPSLNTA 278
AP + A
Sbjct: 374 PAPTTKEPA 382
Score = 47.8 bits (112), Expect = 1e-05
Identities = 39/139 (28%), Positives = 51/139 (36%), Gaps = 23/139 (16%)
Query: 153 KRPRRRSPGSGRPQRARRPVPNAHAPAPSEPDATPLPTARDRDA-------------DPT 199
K P +P P + P P AP+ P P PT + A +PT
Sbjct: 309 KEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKE-PAPTTPKKPAPTTPKEPAPTTPKEPT 367
Query: 200 WTLRFSPSPPKSADASPAPGSPPAPAPTALATCIPEDRAPVRGPGSPPPPPAREDPDSPP 259
T P+P PAP +P PAPTA P+ AP P P P +E +
Sbjct: 368 PTTPKEPAP---TTKEPAPTTPKEPAPTA-----PKKPAPTT-PKEPAPTTPKEPAPTTT 418
Query: 260 GRPEDCAPPPAAPPSLNTA 278
P P AP + +A
Sbjct: 419 KEPSPTTPKEPAPTTTKSA 437
Score = 38.1 bits (87), Expect = 0.011
Identities = 38/127 (29%), Positives = 51/127 (40%), Gaps = 20/127 (15%)
Query: 170 RPVPNAH----APA---PSEP-DATPLPTARDRDADPT-WTLRFSPSPPKS---ADASPA 217
+P P A PA P EP TP A +PT T++ +P+ PK A
Sbjct: 237 KPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSA 296
Query: 218 PGSPPAPAPTAL---ATCIPEDRAPVRGPGSPPPPPAREDPDSP----PGRPEDCAPPPA 270
P +P PAPT A P++ AP P P + P +P P P+ AP
Sbjct: 297 PTTPKEPAPTTTKEPAPTTPKEPAPTT-TKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTP 355
Query: 271 APPSLNT 277
P+ T
Sbjct: 356 KEPAPTT 362
Score = 37.7 bits (86), Expect = 0.015
Identities = 27/98 (27%), Positives = 38/98 (38%), Gaps = 7/98 (7%)
Query: 185 ATPLPTARDRDADPTWTLRFSPSPPKSADASPAPGSPPAPAPTAL--ATCIPEDRAPV-- 240
A P P A P T P+P + PA +P P PT + A P++ AP
Sbjct: 236 AKPTPKAETTTKGPALTTPKEPTP--TTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTT 293
Query: 241 -RGPGSPPPPPAREDPDSPPGRPEDCAPPPAAPPSLNT 277
P +P P + P P++ AP P+ T
Sbjct: 294 KSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTT 331
>gi|189181720 proteoglycan 4 isoform B [Homo sapiens]
Length = 1363
Score = 65.1 bits (157), Expect = 9e-11
Identities = 70/284 (24%), Positives = 95/284 (33%), Gaps = 55/284 (19%)
Query: 2 LLRPRRPPPLAPPAPPSPASPDPEPRTPGDAPGTPPRRPASPSALGELGLPVSPGSAQRT 61
L P+ P P P P S +P P T AP T P+ PA P + SA T
Sbjct: 303 LTTPKEPTPTTPKEPASTTPKEPTPTTIKSAP-TTPKEPA----------PTTTKSAPTT 351
Query: 62 PWSARETELLLGTLLQPAVWRALLLDRRQALPTYRRVSAALAQQQVRRTPAQCRRRYKFL 121
P T T +PA ++ PT + A + TP +
Sbjct: 352 PKEPAPT-----TTKEPAPTTP-----KEPAPTTTKEPAPTTTKSAPTTPKE-------- 393
Query: 122 KDKFREAHGQPPGPFDEQIRKLMGLLGDNGRKRPRRRSPGSGRPQRARRPVPNAHAPAPS 181
A P P K P +P P + P P PAP+
Sbjct: 394 -----PAPTTPKKP------------APTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPT 436
Query: 182 EPDATPLPTARDRDA-----DPTWTLRFSPSPPKSADASPAPGSPPAPAPTALATCIPED 236
P P PTA + A +P T P+P + + SP PAP T A ++
Sbjct: 437 TPKE-PAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKE 495
Query: 237 RAPVR---GPGSPPPPPAREDPDSPPGRPEDCAPPPAAPPSLNT 277
AP P +P P + P P++ AP P+ T
Sbjct: 496 PAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTT 539
Score = 55.5 bits (132), Expect = 7e-08
Identities = 76/310 (24%), Positives = 111/310 (35%), Gaps = 48/310 (15%)
Query: 5 PRRPPPLAP--PAP-----PSPASP-DPEPRTPGDAPGTPPRRPASPSALGELGLPVSPG 56
P+ P P P PAP PSP +P +P P T AP T + PA + P P
Sbjct: 454 PKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAP-TTTKEPAPTTTKSAPTTPKEPS 512
Query: 57 -SAQRTPWSARETELLLGTLLQPAVWR----ALLLDRRQALPTYRRVSAALAQQQVRRTP 111
+ + P E T +PA A + A T ++ + ++ TP
Sbjct: 513 PTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTP 572
Query: 112 AQC-----RRRYKFLKDKFREAHGQPPGPFDEQIRKLMGLLGDNGRKRPRRRSPGSGRPQ 166
+ ++ +K + P P + L + P +P P
Sbjct: 573 KETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEE------LAPTTPEEPTPTTPEEPAPT 626
Query: 167 RARRPVPNA-HAPAPSEPDATPLPTARDRDADPTWTLRFSPSPPKSADAS----PAPGSP 221
+ PN PAP+ P P PT ++ PT +P+ PK + PAP +P
Sbjct: 627 TPKAAAPNTPKEPAPTTP-KEPAPTT-PKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTP 684
Query: 222 PAPAPTALA----------TCIPEDRAPVRGPGSPPPPPAREDPDSP----PGRPEDCAP 267
PAP LA TC + AP G+ P P P +P P P+ AP
Sbjct: 685 KKPAPKELAPTTTKEPTSTTC--DKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAP 742
Query: 268 PPAAPPSLNT 277
P+ T
Sbjct: 743 TTLKEPAPTT 752
Score = 53.9 bits (128), Expect = 2e-07
Identities = 75/303 (24%), Positives = 97/303 (32%), Gaps = 58/303 (19%)
Query: 5 PRRPPPLAPPAP--PSPASPD-PEPRTPGDAPGTPPRRPA-------SPSALGELGLPVS 54
P P LAP P P+P +P+ P P TP A P+ PA +P+ E
Sbjct: 601 PTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTP 660
Query: 55 PGSAQRTPWSARETELLLGTLLQPAVWRALLLDRRQALPTYRRVSAALAQQQVRRTPAQC 114
+A TP T TL +PA ++ PT + T C
Sbjct: 661 KETAPTTPKGTAPT-----TLKEPAPTTPKKPAPKELAPTTTK----------EPTSTTC 705
Query: 115 RRRYKFLKDKFREAHGQPPGPFDEQIRKLMGLLGDNGRKRPRRRSPGSGRPQRARRPVPN 174
+ + P P K P +P P + P P
Sbjct: 706 DKPAPTTPKGTAPTTPKEPAPTTP--------------KEPAPTTPKGTAPTTLKEPAPT 751
Query: 175 A-HAPAPSE--PDATPLPTARDRDAD-PTWTLRFSPSPPK----SADASPAPGSPPAPAP 226
PAP E P T PT+ D PT +P+ PK + PAP +P P P
Sbjct: 752 TPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPP 811
Query: 227 TALATCIPED-RAPVRGPGSP----------PPPPAREDPDSPPGRPEDCAPPPAAPPSL 275
T P + P SP P P A E+ PG P P P
Sbjct: 812 TTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMT 871
Query: 276 NTA 278
TA
Sbjct: 872 TTA 874
Score = 52.0 bits (123), Expect = 8e-07
Identities = 72/295 (24%), Positives = 102/295 (34%), Gaps = 56/295 (18%)
Query: 3 LRPRRPPPLAPPAPPSPASPDPE---PRTPGDAPGTPPRRPA--SPSALGELGLPVSPGS 57
L P P LAP P PA PE P TP + T P PA +P A P P
Sbjct: 583 LTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAP-NTPKEP-- 639
Query: 58 AQRTPWSARETELLLGTLLQPAVWRALLLDRRQALPTYRRVSAALAQQQVRRTPAQCRRR 117
A TP T T +PA ++ PT + +A ++ PA +
Sbjct: 640 APTTPKEPAPT-----TPKEPAP-----TTPKETAPTTPKGTAPTTLKE----PAPTTPK 685
Query: 118 YKFLKDKFREAHGQPPGPFDEQIRKLMGLLGDNGRKRPRRRSPGSGRPQRARRPVPNA-H 176
K+ +P + +P +P P + P P
Sbjct: 686 KPAPKELAPTTTKEPTSTTCD---------------KPAPTTPKGTAPTTPKEPAPTTPK 730
Query: 177 APAPSEPDAT-------PLPTARDRDADPTWTLRFSPSPPKSADASPAPGSPPAPAPTA- 228
PAP+ P T P PT + A + P + PAP +P APT
Sbjct: 731 EPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTP 790
Query: 229 --LATCIPEDRAPVRGPGSPPP-------PPAREDPDSPPGRPEDCAPPPAAPPS 274
A P+ AP P +PPP P ++P + P++ P +A P+
Sbjct: 791 KEPAPTTPKKPAPTT-PETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPT 844
Score = 49.7 bits (117), Expect = 4e-06
Identities = 34/129 (26%), Positives = 47/129 (36%), Gaps = 4/129 (3%)
Query: 153 KRPRRRSPGSGRPQRARRPVPNAHAPAPS---EPDATPLPTARDRDADPTWTLRFSPSPP 209
K P +P + P P AP+ EP T +A +P T P+P
Sbjct: 307 KEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPT 366
Query: 210 KSADASPAPGSPPAPAPTALATCIPEDRAPVRGPGSPPPPPAREDPDSPPGRPEDCAPPP 269
+ +P PAP T A P++ AP P P P +E + P P P
Sbjct: 367 TPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTT-PKKPAPTTPKEPAPTTPKEPTPTTPKE 425
Query: 270 AAPPSLNTA 278
AP + A
Sbjct: 426 PAPTTKEPA 434
Score = 47.8 bits (112), Expect = 1e-05
Identities = 39/139 (28%), Positives = 51/139 (36%), Gaps = 23/139 (16%)
Query: 153 KRPRRRSPGSGRPQRARRPVPNAHAPAPSEPDATPLPTARDRDA-------------DPT 199
K P +P P + P P AP+ P P PT + A +PT
Sbjct: 361 KEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKE-PAPTTPKKPAPTTPKEPAPTTPKEPT 419
Query: 200 WTLRFSPSPPKSADASPAPGSPPAPAPTALATCIPEDRAPVRGPGSPPPPPAREDPDSPP 259
T P+P PAP +P PAPTA P+ AP P P P +E +
Sbjct: 420 PTTPKEPAP---TTKEPAPTTPKEPAPTA-----PKKPAPTT-PKEPAPTTPKEPAPTTT 470
Query: 260 GRPEDCAPPPAAPPSLNTA 278
P P AP + +A
Sbjct: 471 KEPSPTTPKEPAPTTTKSA 489
Score = 38.1 bits (87), Expect = 0.011
Identities = 38/127 (29%), Positives = 51/127 (40%), Gaps = 20/127 (15%)
Query: 170 RPVPNAH----APA---PSEP-DATPLPTARDRDADPT-WTLRFSPSPPKS---ADASPA 217
+P P A PA P EP TP A +PT T++ +P+ PK A
Sbjct: 289 KPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSA 348
Query: 218 PGSPPAPAPTAL---ATCIPEDRAPVRGPGSPPPPPAREDPDSP----PGRPEDCAPPPA 270
P +P PAPT A P++ AP P P + P +P P P+ AP
Sbjct: 349 PTTPKEPAPTTTKEPAPTTPKEPAPTT-TKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTP 407
Query: 271 APPSLNT 277
P+ T
Sbjct: 408 KEPAPTT 414
Score = 37.7 bits (86), Expect = 0.015
Identities = 27/98 (27%), Positives = 38/98 (38%), Gaps = 7/98 (7%)
Query: 185 ATPLPTARDRDADPTWTLRFSPSPPKSADASPAPGSPPAPAPTAL--ATCIPEDRAPV-- 240
A P P A P T P+P + PA +P P PT + A P++ AP
Sbjct: 288 AKPTPKAETTTKGPALTTPKEPTP--TTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTT 345
Query: 241 -RGPGSPPPPPAREDPDSPPGRPEDCAPPPAAPPSLNT 277
P +P P + P P++ AP P+ T
Sbjct: 346 KSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTT 383
>gi|67190163 proteoglycan 4 isoform A [Homo sapiens]
Length = 1404
Score = 65.1 bits (157), Expect = 9e-11
Identities = 70/284 (24%), Positives = 95/284 (33%), Gaps = 55/284 (19%)
Query: 2 LLRPRRPPPLAPPAPPSPASPDPEPRTPGDAPGTPPRRPASPSALGELGLPVSPGSAQRT 61
L P+ P P P P S +P P T AP T P+ PA P + SA T
Sbjct: 344 LTTPKEPTPTTPKEPASTTPKEPTPTTIKSAP-TTPKEPA----------PTTTKSAPTT 392
Query: 62 PWSARETELLLGTLLQPAVWRALLLDRRQALPTYRRVSAALAQQQVRRTPAQCRRRYKFL 121
P T T +PA ++ PT + A + TP +
Sbjct: 393 PKEPAPT-----TTKEPAPTTP-----KEPAPTTTKEPAPTTTKSAPTTPKE-------- 434
Query: 122 KDKFREAHGQPPGPFDEQIRKLMGLLGDNGRKRPRRRSPGSGRPQRARRPVPNAHAPAPS 181
A P P K P +P P + P P PAP+
Sbjct: 435 -----PAPTTPKKP------------APTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPT 477
Query: 182 EPDATPLPTARDRDA-----DPTWTLRFSPSPPKSADASPAPGSPPAPAPTALATCIPED 236
P P PTA + A +P T P+P + + SP PAP T A ++
Sbjct: 478 TPKE-PAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKE 536
Query: 237 RAPVR---GPGSPPPPPAREDPDSPPGRPEDCAPPPAAPPSLNT 277
AP P +P P + P P++ AP P+ T
Sbjct: 537 PAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTT 580
Score = 55.5 bits (132), Expect = 7e-08
Identities = 76/310 (24%), Positives = 111/310 (35%), Gaps = 48/310 (15%)
Query: 5 PRRPPPLAP--PAP-----PSPASP-DPEPRTPGDAPGTPPRRPASPSALGELGLPVSPG 56
P+ P P P PAP PSP +P +P P T AP T + PA + P P
Sbjct: 495 PKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAP-TTTKEPAPTTTKSAPTTPKEPS 553
Query: 57 -SAQRTPWSARETELLLGTLLQPAVWR----ALLLDRRQALPTYRRVSAALAQQQVRRTP 111
+ + P E T +PA A + A T ++ + ++ TP
Sbjct: 554 PTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTP 613
Query: 112 AQC-----RRRYKFLKDKFREAHGQPPGPFDEQIRKLMGLLGDNGRKRPRRRSPGSGRPQ 166
+ ++ +K + P P + L + P +P P
Sbjct: 614 KETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEE------LAPTTPEEPTPTTPEEPAPT 667
Query: 167 RARRPVPNA-HAPAPSEPDATPLPTARDRDADPTWTLRFSPSPPKSADAS----PAPGSP 221
+ PN PAP+ P P PT ++ PT +P+ PK + PAP +P
Sbjct: 668 TPKAAAPNTPKEPAPTTP-KEPAPTT-PKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTP 725
Query: 222 PAPAPTALA----------TCIPEDRAPVRGPGSPPPPPAREDPDSP----PGRPEDCAP 267
PAP LA TC + AP G+ P P P +P P P+ AP
Sbjct: 726 KKPAPKELAPTTTKEPTSTTC--DKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAP 783
Query: 268 PPAAPPSLNT 277
P+ T
Sbjct: 784 TTLKEPAPTT 793
Score = 53.9 bits (128), Expect = 2e-07
Identities = 75/303 (24%), Positives = 97/303 (32%), Gaps = 58/303 (19%)
Query: 5 PRRPPPLAPPAP--PSPASPD-PEPRTPGDAPGTPPRRPA-------SPSALGELGLPVS 54
P P LAP P P+P +P+ P P TP A P+ PA +P+ E
Sbjct: 642 PTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTP 701
Query: 55 PGSAQRTPWSARETELLLGTLLQPAVWRALLLDRRQALPTYRRVSAALAQQQVRRTPAQC 114
+A TP T TL +PA ++ PT + T C
Sbjct: 702 KETAPTTPKGTAPT-----TLKEPAPTTPKKPAPKELAPTTTK----------EPTSTTC 746
Query: 115 RRRYKFLKDKFREAHGQPPGPFDEQIRKLMGLLGDNGRKRPRRRSPGSGRPQRARRPVPN 174
+ + P P K P +P P + P P
Sbjct: 747 DKPAPTTPKGTAPTTPKEPAPTTP--------------KEPAPTTPKGTAPTTLKEPAPT 792
Query: 175 A-HAPAPSE--PDATPLPTARDRDAD-PTWTLRFSPSPPK----SADASPAPGSPPAPAP 226
PAP E P T PT+ D PT +P+ PK + PAP +P P P
Sbjct: 793 TPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPP 852
Query: 227 TALATCIPED-RAPVRGPGSP----------PPPPAREDPDSPPGRPEDCAPPPAAPPSL 275
T P + P SP P P A E+ PG P P P
Sbjct: 853 TTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMT 912
Query: 276 NTA 278
TA
Sbjct: 913 TTA 915
Score = 52.0 bits (123), Expect = 8e-07
Identities = 72/295 (24%), Positives = 102/295 (34%), Gaps = 56/295 (18%)
Query: 3 LRPRRPPPLAPPAPPSPASPDPE---PRTPGDAPGTPPRRPA--SPSALGELGLPVSPGS 57
L P P LAP P PA PE P TP + T P PA +P A P P
Sbjct: 624 LTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAP-NTPKEP-- 680
Query: 58 AQRTPWSARETELLLGTLLQPAVWRALLLDRRQALPTYRRVSAALAQQQVRRTPAQCRRR 117
A TP T T +PA ++ PT + +A ++ PA +
Sbjct: 681 APTTPKEPAPT-----TPKEPAP-----TTPKETAPTTPKGTAPTTLKE----PAPTTPK 726
Query: 118 YKFLKDKFREAHGQPPGPFDEQIRKLMGLLGDNGRKRPRRRSPGSGRPQRARRPVPNA-H 176
K+ +P + +P +P P + P P
Sbjct: 727 KPAPKELAPTTTKEPTSTTCD---------------KPAPTTPKGTAPTTPKEPAPTTPK 771
Query: 177 APAPSEPDAT-------PLPTARDRDADPTWTLRFSPSPPKSADASPAPGSPPAPAPTA- 228
PAP+ P T P PT + A + P + PAP +P APT
Sbjct: 772 EPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTP 831
Query: 229 --LATCIPEDRAPVRGPGSPPP-------PPAREDPDSPPGRPEDCAPPPAAPPS 274
A P+ AP P +PPP P ++P + P++ P +A P+
Sbjct: 832 KEPAPTTPKKPAPTT-PETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPT 885
Score = 49.7 bits (117), Expect = 4e-06
Identities = 34/129 (26%), Positives = 47/129 (36%), Gaps = 4/129 (3%)
Query: 153 KRPRRRSPGSGRPQRARRPVPNAHAPAPS---EPDATPLPTARDRDADPTWTLRFSPSPP 209
K P +P + P P AP+ EP T +A +P T P+P
Sbjct: 348 KEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPT 407
Query: 210 KSADASPAPGSPPAPAPTALATCIPEDRAPVRGPGSPPPPPAREDPDSPPGRPEDCAPPP 269
+ +P PAP T A P++ AP P P P +E + P P P
Sbjct: 408 TPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTT-PKKPAPTTPKEPAPTTPKEPTPTTPKE 466
Query: 270 AAPPSLNTA 278
AP + A
Sbjct: 467 PAPTTKEPA 475
Score = 47.8 bits (112), Expect = 1e-05
Identities = 39/139 (28%), Positives = 51/139 (36%), Gaps = 23/139 (16%)
Query: 153 KRPRRRSPGSGRPQRARRPVPNAHAPAPSEPDATPLPTARDRDA-------------DPT 199
K P +P P + P P AP+ P P PT + A +PT
Sbjct: 402 KEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKE-PAPTTPKKPAPTTPKEPAPTTPKEPT 460
Query: 200 WTLRFSPSPPKSADASPAPGSPPAPAPTALATCIPEDRAPVRGPGSPPPPPAREDPDSPP 259
T P+P PAP +P PAPTA P+ AP P P P +E +
Sbjct: 461 PTTPKEPAP---TTKEPAPTTPKEPAPTA-----PKKPAPTT-PKEPAPTTPKEPAPTTT 511
Query: 260 GRPEDCAPPPAAPPSLNTA 278
P P AP + +A
Sbjct: 512 KEPSPTTPKEPAPTTTKSA 530
Score = 38.1 bits (87), Expect = 0.011
Identities = 38/127 (29%), Positives = 51/127 (40%), Gaps = 20/127 (15%)
Query: 170 RPVPNAH----APA---PSEP-DATPLPTARDRDADPT-WTLRFSPSPPKS---ADASPA 217
+P P A PA P EP TP A +PT T++ +P+ PK A
Sbjct: 330 KPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSA 389
Query: 218 PGSPPAPAPTAL---ATCIPEDRAPVRGPGSPPPPPAREDPDSP----PGRPEDCAPPPA 270
P +P PAPT A P++ AP P P + P +P P P+ AP
Sbjct: 390 PTTPKEPAPTTTKEPAPTTPKEPAPTT-TKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTP 448
Query: 271 APPSLNT 277
P+ T
Sbjct: 449 KEPAPTT 455
Score = 37.7 bits (86), Expect = 0.015
Identities = 27/98 (27%), Positives = 38/98 (38%), Gaps = 7/98 (7%)
Query: 185 ATPLPTARDRDADPTWTLRFSPSPPKSADASPAPGSPPAPAPTAL--ATCIPEDRAPV-- 240
A P P A P T P+P + PA +P P PT + A P++ AP
Sbjct: 329 AKPTPKAETTTKGPALTTPKEPTP--TTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTT 386
Query: 241 -RGPGSPPPPPAREDPDSPPGRPEDCAPPPAAPPSLNT 277
P +P P + P P++ AP P+ T
Sbjct: 387 KSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTT 424
>gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo
sapiens]
Length = 5537
Score = 65.1 bits (157), Expect = 9e-11
Identities = 81/285 (28%), Positives = 105/285 (36%), Gaps = 38/285 (13%)
Query: 2 LLRPRRPPPLAPPAPPSPASPDPEPRTPGDAPGTPPRRPASPSALGELGLPVSPGSAQRT 61
LL P PL+PP SP SP PE P P P P AL L P+ + +
Sbjct: 440 LLPPPEESPLSPPPEESPTSPPPEASRLSPPPEELPASPL-PEAL-HLSRPL-----EES 492
Query: 62 PWSARETELLLGTLLQPAVWRALLLDRRQALPTYRRVSAALAQQQVRRTPAQCRRRYKFL 121
P S E L + + + L + + P S AL TP L
Sbjct: 493 PLSPPPEESPLSPPPESSPFSPLE-ESPLSPPEESPPSPAL------ETPLSPPPEASPL 545
Query: 122 KDKFREAHGQPP------GPFDEQIRKLMGLLGDNGRKRPRRRSPGSGRPQRARRPVPNA 175
F E+ PP P E R L ++ P SP S P+ +R P
Sbjct: 546 SPPFEESPLSPPPEELPTSPPPEASR-LSPPPEESPMSPPPEESPMSPPPEASRLFPPFE 604
Query: 176 HAPAPSEPDATPLPTARDRDADPTWTLRFSPSPPKSADASPAPGSPPAPAPTALATCIPE 235
+P P+ +PL + P R SP PP+ + SP P P P ++ P
Sbjct: 605 ESPLSPPPEESPL-------SPPPEASRLSP-PPEDSPMSPPPEESPMSPPPEVSRLSP- 655
Query: 236 DRAPVRGPGSPPP------PPAREDPDSPPGRPEDCAPPPAAPPS 274
PV SPPP PP E P SPP +PPP P+
Sbjct: 656 --LPVVSRLSPPPEESPLSPPPEESPTSPPPEASRLSPPPEDSPT 698
Score = 64.3 bits (155), Expect = 1e-10
Identities = 73/269 (27%), Positives = 105/269 (39%), Gaps = 46/269 (17%)
Query: 2 LLRPRRPPPLAPPAPPSPASPDPE--PRTP-GDAPGTPPRR-PASPSALGELGLPVSPGS 57
L RP PL+PP SP SP PE P +P ++P +PP P SP+ L P+SP
Sbjct: 485 LSRPLEESPLSPPPEESPLSPPPESSPFSPLEESPLSPPEESPPSPA----LETPLSP-P 539
Query: 58 AQRTPWSARETELLLGTLLQPAVWRALLLDRRQALPTYRRVSAALAQQQVRRTPAQCRRR 117
+ +P L P + L + LPT A+ +P
Sbjct: 540 PEASP-------------LSPPFEESPLSPPPEELPTSPPPEASRLSPPPEESP------ 580
Query: 118 YKFLKDKFREAHGQPPGPFDEQIRKLMGLLGDNGRKRPRRRSPGSGRPQRARRPVPNAHA 177
+ E+ PP + +L ++ P SP S P+ +R P +
Sbjct: 581 ---MSPPPEESPMSPP----PEASRLFPPFEESPLSPPPEESPLSPPPEASRLSPPPEDS 633
Query: 178 PAPSEPDATPLPTARDRDADPTWTLRFSPSPPKSADASPAPGSPPAPAPTALATCIPEDR 237
P P+ +P+ + P R SP P S + P SP +P P T P +
Sbjct: 634 PMSPPPEESPM-------SPPPEVSRLSPLPVVSRLSPPPEESPLSPPPEESPTSPPPEA 686
Query: 238 APVRGP--GSPPPPPAREDPDSPPGRPED 264
+ + P SP PP + P SPP PED
Sbjct: 687 SRLSPPPEDSPTSPPPEDSPASPP--PED 713
Score = 50.4 bits (119), Expect = 2e-06
Identities = 80/318 (25%), Positives = 108/318 (33%), Gaps = 40/318 (12%)
Query: 5 PRRPPPLAPPAPPSPASPDPEPRT----PGDAPGTPPRR--PASPSALGEL-GLPVSPGS 57
P PL+PP SP SP PE P D+P +PP PASP L LP+
Sbjct: 665 PPEESPLSPPPEESPTSPPPEASRLSPPPEDSPTSPPPEDSPASPPPEDSLMSLPLEESP 724
Query: 58 AQRTPWSARETELLLGTLLQPAVWRALLLDRRQALPTYRRVSAALAQQQVRRTPAQ-CRR 116
P + G L P L R P +S + + P + C
Sbjct: 725 LLPLPEEPQLCPRSEGPHLSPRPEEPHLSPR----PEEPHLSPQAEEPHLSPQPEEPCLC 780
Query: 117 RYKFLKDKFREAHGQPPGPFDEQIRKLMGLLGDNGRKRPRRRSPGSGRPQRARRPVPNAH 176
+A G P E++ + + SP P + +P +
Sbjct: 781 AVPEEPHLSPQAEGPHLSPQPEELHL-------SPQTEEPHLSPVPEEPCLSPQPEESHL 833
Query: 177 APAPSEPDATPLPTARDRDADPTWTLRFSPSPPKSADASPAPGSPPAPAPTALATCIPED 236
+P EP +P P + L P P+ PG PAP L E
Sbjct: 834 SPQSEEPCLSPRPEESHLSPE----LEKPPLSPRPEKPPEEPGQCPAPEELPLFPPPGEP 889
Query: 237 R-APVRG------PGSPPPPPARED-PDSPPGRPE--------DCAPPPAAPPSLNTALL 280
+P+ G PG PP P E+ P SP G P D PPP + P + A
Sbjct: 890 SLSPLLGEPALSEPGEPPLSPLPEELPLSPSGEPSLSPQLMPPDPLPPPLS-PIITAAAP 948
Query: 281 QTLGHLGDIANILGPLRD 298
L LG++ G D
Sbjct: 949 PALSPLGELEYPFGAKGD 966
Score = 50.1 bits (118), Expect = 3e-06
Identities = 77/298 (25%), Positives = 108/298 (36%), Gaps = 62/298 (20%)
Query: 5 PRRPPPLAPPAPPSPASPDPEPRTPGDAPGTPPRRPASPS--------ALGELGLPVSPG 56
P +PP L + P P TP PGTP +P++P +L L +P SPG
Sbjct: 2206 PAQPPMLGASSRPGAGQPGEFHTTP---PGTPRHQPSTPDPFLKPRCPSLDNLAVPESPG 2262
Query: 57 SAQRTPWSARETELLLGTLLQPAVWRALLLDRRQ---ALPTYRRVSAALAQQQVRRTPAQ 113
+ +E LL +AL + + + + P+Y + T
Sbjct: 2263 VG-----GGKASEPLLSPPPFGESRKALEVKKEELGASSPSYGPPNLGFVDSPSSGT--- 2314
Query: 114 CRRRYKFLKDKFREAHGQPPGPFDEQIRKLMGLLGDNGRKRPRRRSPGSG-RPQRARRPV 172
L+ K + P P Q+ +SPG G RPQ P
Sbjct: 2315 ---HLGGLELKTPDVFKAPLTPRASQVEP---------------QSPGLGLRPQEP--PP 2354
Query: 173 PNAHAPAP-SEPDATPLPTARDRDADPTWTLRFSPSPPKSADASPAPGSPPAPAPTALAT 231
A AP+P S PD + D A P T R P PP+S A P P P A+
Sbjct: 2355 AQALAPSPPSHPDIFRPGSYTDPYAQPPLTPRPQPPPPESCCALPPRSLPSDPFSRVPAS 2414
Query: 232 CIPEDRAPVRGPGSP-----------PPPPAREDPD---SPPGRPEDCAP--PPAAPP 273
P+ ++ + P +P P P + PD PP RP+ P P PP
Sbjct: 2415 --PQSQSSSQSPLTPRPLSAEAFCPSPVTPRFQSPDPYSRPPSRPQSRDPFAPLHKPP 2470
Score = 41.6 bits (96), Expect = 0.001
Identities = 39/142 (27%), Positives = 54/142 (38%), Gaps = 7/142 (4%)
Query: 133 PGPFDEQIRKLMGLLGDNG-RKRPRRRSPGSGRPQRARRPVPNAHAPAPSEPDATPLPTA 191
PGP + + L G G + P+ +P + P + +P P E +P P A
Sbjct: 409 PGPLQCEAKPL----GKAGVQLEPQLEAPLNEEMPLLPPPEESPLSPPPEESPTSPPPEA 464
Query: 192 RDRDADPTWTLRFSPSPPKSADASPAPGSPPAPAPTALATCIPEDRAPVRGPGSPPPPPA 251
R + P L SP P + P SP +P P P + +P P P
Sbjct: 465 -SRLSPPPEELPASPLPEALHLSRPLEESPLSPPPEESPLSPPPESSPFSPLEESPLSPP 523
Query: 252 REDPDSPPGRPEDCAPPPAAPP 273
E P S P +PPP A P
Sbjct: 524 EESPPS-PALETPLSPPPEASP 544
Score = 40.4 bits (93), Expect = 0.002
Identities = 72/276 (26%), Positives = 94/276 (34%), Gaps = 29/276 (10%)
Query: 21 SPDP-EPRTPGDAPG-TPPRRPASPSALGEL-GLPVSPGSAQRTPWSARETELLLGTLLQ 77
SP+P EP +P G T P P +P+ GE GL + S QR W E L T+
Sbjct: 1963 SPEPGEPDSPWTGSGGTTPSTPTTPTTEGEGDGLSYNQRSLQR--WEKDEELGQLSTISP 2020
Query: 78 PAVWRALLLDRRQALPTYRRVSAALAQQQVRRTPAQCRRRYKFLKDKFREAH--GQPPGP 135
+ +Q P + + + R+ PA + Y R AH +
Sbjct: 2021 VLYANINFPNLKQDYPDWSSRCKQIMKLW-RKVPAADKAPYLQKAKDNRAAHRINKVQKQ 2079
Query: 136 FDEQIRKLMGLLGDNGRKRPRRR-------SPGS-GRPQRARRPV-----PNAHAPAPSE 182
+ QI K +GD RK R PG+ G P A P P A +
Sbjct: 2080 AESQINK-QTKVGDIARKTDRPALHLRIPPQPGALGSPPPAAAPTIFIGSPTTPAGLSTS 2138
Query: 183 PDATPLPTARDRDADPTWTLRFSPSPPKSADASPAPGSPPAPAPTALATCIP-EDRAPVR 241
D P A + F PP+ P P+ P LA P E R P
Sbjct: 2139 ADGFLKPPAGSVPGPDSPGELFLKLPPQ------VPAQVPSQDPFGLAPAYPLEPRFPTA 2192
Query: 242 GPGSPPPPPAREDPDSPPGRPEDCAPPPAAPPSLNT 277
P PP P P PP P P +T
Sbjct: 2193 PPTYPPYPSPTGAPAQPPMLGASSRPGAGQPGEFHT 2228
Score = 39.3 bits (90), Expect = 0.005
Identities = 79/302 (26%), Positives = 97/302 (32%), Gaps = 52/302 (17%)
Query: 3 LRPRRPPPLAPPAPPSPASPD---PEPRT-----PGDAPGTPPRRPASPSALGELGLPVS 54
LRP+ PPP AP P+ PD P T P P P P S AL LP
Sbjct: 2347 LRPQEPPPAQALAPSPPSHPDIFRPGSYTDPYAQPPLTPRPQPPPPESCCALPPRSLPSD 2406
Query: 55 PGSAQRTPWSARETELLLGTLLQPAVWRALLLDRRQALPTYRRVSAALAQQQVRRTPAQC 114
P S R P S + + P R L + P R + R P++
Sbjct: 2407 PFS--RVPASPQSQ----SSSQSPLTPRPLSAEAFCPSPVTPRFQ---SPDPYSRPPSRP 2457
Query: 115 RRRYKFLKDKFREAHGQPPGPFDEQIRKLMGLLGDNGRKRPRRRSPGSGRPQRA--RRPV 172
+ R D F H +PP P ++ G L S G+G A P
Sbjct: 2458 QSR-----DPFAPLH-KPPRPQPPEVAFKAGSLA--------HTSLGAGGFPAALPAGPA 2503
Query: 173 PNAHAPAPS--EPDATPLPTARDRDADPT---WTLRFSPSPPKSADASPAPGSPP----- 222
HA PS P+ P P+ +T + P P PG PP
Sbjct: 2504 GELHAKVPSGQPPNFVRSPGTGAFVGTPSPMRFTFPQAVGEPSLKPPVPQPGLPPPHGIN 2563
Query: 223 ---APAPT------ALATCIPEDRAPVRGPGSPPPPPAREDPDSPPGRPEDCAPPPAAPP 273
P PT T + P P P E P RP PPPA
Sbjct: 2564 SHFGPGPTLGKPQSTNYTVATGNFHPSGSPLGPSSGSTGESYGLSPLRPPSVLPPPAPDG 2623
Query: 274 SL 275
SL
Sbjct: 2624 SL 2625
Score = 38.1 bits (87), Expect = 0.011
Identities = 29/85 (34%), Positives = 34/85 (40%), Gaps = 14/85 (16%)
Query: 177 APAPSEPDATPLPTARDRDADPTWTLRFSPSPPKSADASPAPGSPPAPAPTALATCIPED 236
AP P EP P P A + PT L P+ P + PP P+P LA+ PE
Sbjct: 4908 APPPEEPSPPPSPLAPSPASPPTEPLVELPTEPLA--------EPPVPSPLPLASS-PES 4958
Query: 237 RAPVRGPGSPPPPPAREDPDSPPGR 261
P P P E DS P R
Sbjct: 4959 ARP-----KPRARPPEEGEDSRPPR 4978
Score = 36.6 bits (83), Expect = 0.033
Identities = 72/299 (24%), Positives = 97/299 (32%), Gaps = 51/299 (17%)
Query: 16 PPSPASPDPEPRTPGDAPGTPPRRPASPSALGELGLPVSPGSAQRTPWSARETELLLGTL 75
P P P G P P P S G G+ + P Q L G L
Sbjct: 4155 PQQPMLERPMQNNTGPQPPKPG--PVLQSGQGLPGVGIMPTVGQLRAQ-------LQGVL 4205
Query: 76 LQPAVWRALLLDRRQALPTYRRVSAALAQQQVRRTPAQCRRRYKFLKDKFREAHGQPPGP 135
+ R L ++Q L Q VR+TP Q PG
Sbjct: 4206 AKNPQLRHLSPQQQQQLQALLMQRQLQQSQAVRQTPPY-----------------QEPGT 4248
Query: 136 FDEQIRKLMGLLGDNGRKRPRRRSPGSGRPQRARRPVPNAHA-PAPSEPDATPLPTARDR 194
Q L GLLG + G P P+ A P P P P P
Sbjct: 4249 ---QTSPLQGLLGCQPQL--------GGFPGPQTGPLQELGAGPRPQGPPRLPAPPGALS 4297
Query: 195 DADPTWTLRFSPSPPKSADASPAPGSPPAPAPTALATCIPEDRAPVRGPGSPPPPPARED 254
+ P+PP S SP P+ P+ + E + P PG+P P +
Sbjct: 4298 TGPVLGPVH--PTPPPS---SPQEPKRPSQLPSPSSQLPTEAQLPPTHPGTPKPQGPTLE 4352
Query: 255 PDSPPGRPEDCAPPPAAPPSLNTALLQTLGHLGDIANILGPLR-DQLLTLNQHVEQLRG 312
P PPGR PAA +T + LG N+ + +Q + H++Q+ G
Sbjct: 4353 P--PPGRVS-----PAAAQLADTLFSKGLGPWDPPDNLAETQKPEQSSLVPGHLDQVNG 4404
Score = 36.2 bits (82), Expect = 0.043
Identities = 26/71 (36%), Positives = 29/71 (40%), Gaps = 15/71 (21%)
Query: 206 PSPPKSADASPAPGSPPAPAPTALATCIPEDRAPVRGPGSPPPPPAREDPDS-------- 257
PSPP S A P+P SPP L T P+ P P P P P+S
Sbjct: 4914 PSPPPSPLA-PSPASPPTEPLVELPT------EPLAEPPVPSPLPLASSPESARPKPRAR 4966
Query: 258 PPGRPEDCAPP 268
PP ED PP
Sbjct: 4967 PPEEGEDSRPP 4977
Score = 35.8 bits (81), Expect = 0.057
Identities = 24/58 (41%), Positives = 26/58 (44%), Gaps = 5/58 (8%)
Query: 5 PRRPPPLAPPAPPSPASPDPEPRTPGDAPGTPPRRPASPSALGELGLPVSPGSAQRTP 62
P P P P PSPASP EP + P P P PS L L SP SA+ P
Sbjct: 4911 PEEPSPPPSPLAPSPASPPTEPLV--ELPTEPLAEPPVPS---PLPLASSPESARPKP 4963
Score = 35.4 bits (80), Expect = 0.074
Identities = 40/141 (28%), Positives = 54/141 (38%), Gaps = 28/141 (19%)
Query: 162 SGRPQRARRPVPNAHAPAPSEPDATPLPTARDRDA-DPTWTLRF-----SPSPPKSADAS 215
SG P + + +P P P P +P+ TA A P L + S P+S A+
Sbjct: 920 SGEPSLSPQLMP----PDPLPPPLSPIITAAAPPALSPLGELEYPFGAKGDSDPESPLAA 975
Query: 216 PAPGSPPAPAPTALATCIPEDRAPVRGPGSPPPPPAREDPDSPPGRPEDCAP-------- 267
P +P +P P A T PE P+ P SP P P P C+P
Sbjct: 976 PILETPISPPPEANCTD-PEPVPPMILPPSPGSPVGPASPILMEPLPPQCSPLLQHSLVP 1034
Query: 268 ---------PPAAPPSLNTAL 279
PPA P S+ + L
Sbjct: 1035 QNSPPSQCSPPALPLSVPSPL 1055
Score = 31.6 bits (70), Expect = 1.1
Identities = 33/125 (26%), Positives = 40/125 (32%), Gaps = 27/125 (21%)
Query: 170 RPVPNAHAP-----APSEPDATPLPTARDRDADPTWTLRFSPSPPKSADASPAPGSPPAP 224
R V H P +P EP TP +P PK + P P
Sbjct: 359 RSVAEQHTPVCSRFSPPEPGDTPTD-------EPDALYVACQGQPKGGHVTSMQPKEPGP 411
Query: 225 APT-------ALATCIPEDRAPVRG--PGSPPP------PPAREDPDSPPGRPEDCAPPP 269
A P+ AP+ P PPP PP E P SPP +PPP
Sbjct: 412 LQCEAKPLGKAGVQLEPQLEAPLNEEMPLLPPPEESPLSPPPEESPTSPPPEASRLSPPP 471
Query: 270 AAPPS 274
P+
Sbjct: 472 EELPA 476
Score = 31.2 bits (69), Expect = 1.4
Identities = 23/67 (34%), Positives = 27/67 (40%), Gaps = 8/67 (11%)
Query: 215 SPAPGSPPAPAPTALATCIPEDR--APVRGPGSPPPPPAREDPDSPPGRP------EDCA 266
SPAP P + T + + + AP SPPP P P SPP P E A
Sbjct: 4883 SPAPEPPTQHSYTYNVSNLDVRQLSAPPPEEPSPPPSPLAPSPASPPTEPLVELPTEPLA 4942
Query: 267 PPPAAPP 273
PP P
Sbjct: 4943 EPPVPSP 4949
Score = 30.8 bits (68), Expect = 1.8
Identities = 19/48 (39%), Positives = 20/48 (41%), Gaps = 6/48 (12%)
Query: 10 PLAPPAPPSPASPDPEPRTPGDAPGTPPRRPASPSALGELGLPVSPGS 57
PLA P +P SP PE P P P SP G PV P S
Sbjct: 972 PLAAPILETPISPPPEANCTDPEPVPPMILPPSP------GSPVGPAS 1013
Score = 30.8 bits (68), Expect = 1.8
Identities = 27/90 (30%), Positives = 34/90 (37%), Gaps = 21/90 (23%)
Query: 2 LLRPRRPPPLAPPAPPSPASPDPEPRTPGDAPGTPPR-----RPASP------------- 43
LLR P PL P P PA+ EPR P P+ R SP
Sbjct: 3085 LLRGVEPGPLGPEERPPPAADASEPRLASVLPEVKPKVEEGGRHPSPCQFTIATPKVEPA 3144
Query: 44 SALGELGLPVSPGSAQRTPWSARETELLLG 73
A LGL + PG + +R+T + G
Sbjct: 3145 PAANSLGLGLKPGQSM---MGSRDTRMGTG 3171
Score = 30.4 bits (67), Expect = 2.4
Identities = 21/65 (32%), Positives = 24/65 (36%), Gaps = 14/65 (21%)
Query: 9 PPLAPPAPPSPASPDPEPRTPGDAPG----------TPPRRPASPSALGELGLP----VS 54
P L P P P S EP+ P P PP P +P G P VS
Sbjct: 4300 PVLGPVHPTPPPSSPQEPKRPSQLPSPSSQLPTEAQLPPTHPGTPKPQGPTLEPPPGRVS 4359
Query: 55 PGSAQ 59
P +AQ
Sbjct: 4360 PAAAQ 4364
Score = 30.0 bits (66), Expect = 3.1
Identities = 23/64 (35%), Positives = 26/64 (40%), Gaps = 12/64 (18%)
Query: 4 RPRRPPPLAPPAPPSPASPDP-----EPRTPGDAPGTPPRRPASPSALGELGLPVSPGSA 58
RP+ PP L PAPP S P P P +P P R PS +L P A
Sbjct: 4282 RPQGPPRL--PAPPGALSTGPVLGPVHPTPPPSSPQEPKRPSQLPSPSSQL-----PTEA 4334
Query: 59 QRTP 62
Q P
Sbjct: 4335 QLPP 4338
Score = 30.0 bits (66), Expect = 3.1
Identities = 21/55 (38%), Positives = 26/55 (47%), Gaps = 7/55 (12%)
Query: 220 SPPAPAPTALATCIPEDRAPVRGPGSPPPPPAREDPDSPPGRPEDCAPPPAAPPS 274
SP PT + VR +PPP E+P SPP P AP PA+PP+
Sbjct: 4883 SPAPEPPTQHSYTYNVSNLDVRQLSAPPP----EEP-SPP--PSPLAPSPASPPT 4930
Score = 29.3 bits (64), Expect = 5.3
Identities = 21/56 (37%), Positives = 25/56 (44%), Gaps = 4/56 (7%)
Query: 2 LLRPRRPPPLAPPAPPSPASPDPEPRTPGDAPGTP--PRRPASPSALGELGLPVSP 55
L P P++P PP DPEP P P +P P PASP + L SP
Sbjct: 973 LAAPILETPISP--PPEANCTDPEPVPPMILPPSPGSPVGPASPILMEPLPPQCSP 1026
>gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo
sapiens]
Length = 855
Score = 63.2 bits (152), Expect = 3e-10
Identities = 90/309 (29%), Positives = 117/309 (37%), Gaps = 53/309 (17%)
Query: 2 LLRPRRPPPLA---PPAPPSPASPDPEPRTPGDAPG-TPPRRPASPSALGELGLPVSPGS 57
L P R P A P AP P+ P P+ P TPPR+ A+P ALG L S
Sbjct: 249 LSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAP-ALGPLS---SSPL 304
Query: 58 AQRTPWSARETELLLGTLLQPAVWRALLLDRRQALPTYRRVSAALAQQQVRRTPAQ---- 113
A +P +A +++ PA + L + A P + A ++ P+
Sbjct: 305 ATPSPSAALQSQ---APPTLPATPHSSSLTCQLATPLPLAPPSPSAPPSLQTLPSPPATP 361
Query: 114 -CRRRYKFLKDKFREAHGQPPGPFDEQIRKLMGLLGDNGRKRPRRRSPGSGRPQRARRPV 172
+ + H P P P P P A P+
Sbjct: 362 PSQATTSLGSPTLQATHSFLPSP----------------PLSPLATPPPQAPPALALPPL 405
Query: 173 ---PNAHAPAPSEPDATPLPTARDRDADPTWTLRFSP----------SPPKSADASPAPG 219
P+ A P P ATP P A + A FSP SPP S SP+
Sbjct: 406 QAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPS-A 464
Query: 220 SPPAPAPTALATCIPEDRAPVRGPGSPP-PPPAREDPDSPP---GRPEDCA-PPPAAPPS 274
+PP+ AP +LA P + P P SPP P A P +PP P A PPP APP+
Sbjct: 465 TPPSQAPPSLAA--PPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPA 522
Query: 275 LNTALLQTL 283
L T LQ L
Sbjct: 523 LATPPLQAL 531
Score = 56.6 bits (135), Expect = 3e-08
Identities = 79/306 (25%), Positives = 101/306 (33%), Gaps = 37/306 (12%)
Query: 3 LRPRRPPPLAPP----APP------SP-ASPDPEPRTPGDAPGTPPRRPASPSALGELG- 50
L+ RPP + PP AP SP A+P P AP T P P S S +L
Sbjct: 277 LQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAALQSQAPPTLPATPHSSSLTCQLAT 336
Query: 51 -LPVSPGSAQRTPWSARETELLLGTLLQPAVWRALLLDRRQALPTYRRVSAALAQQQVRR 109
LP++P S P L TL P PT + + L +
Sbjct: 337 PLPLAPPSPSAPP--------SLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSP 388
Query: 110 TPAQCRRRYKFLKDKFREAHGQPPGPFDEQIRKLMGLLGDNGRKRPRRRSPGSGRPQRAR 169
+ L +A PP N ++P S P
Sbjct: 389 LATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPV 448
Query: 170 RPVPNAHAPAPSEPDATPLPTARDRDADPTWTLRFSPSPPKSADASPAPGSPPAPAPTAL 229
+ + A P P ATP A A P L+ PSPP S SP+ PP P
Sbjct: 449 QAPFSPPASPPVSPSATPPSQAPPSLAAPP--LQVPPSPPASPPMSPSATPPPQAPPPLA 506
Query: 230 ATCIPEDRAPVRGPGSPPPPPAREDPDSPPGRPED--------------CAPPPAAPPSL 275
A + + P + P + PP + P P P PPP APP L
Sbjct: 507 APPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVL 566
Query: 276 NTALLQ 281
LLQ
Sbjct: 567 AAPLLQ 572
Score = 53.9 bits (128), Expect = 2e-07
Identities = 92/334 (27%), Positives = 118/334 (35%), Gaps = 62/334 (18%)
Query: 2 LLRPRRPPPLAPPAPPSPAS---------------------------PDPEPRT-PGDAP 33
LL PR P PP P +PA+ P+ PR P +
Sbjct: 24 LLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTRSA 83
Query: 34 GTPPRRPAS---PSALGELGLPV---------SPGSAQRT--PWSARETELLLGTLLQPA 79
GT R PAS S GE P SPG A T P + L + A
Sbjct: 84 GTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVA 143
Query: 80 VWRALLLDRRQALPTYRRVSAALAQQQVRRTPAQCRRRYKFLKDKF--REAHGQPPGPFD 137
+A +R AL R + +PA RR + R A P P
Sbjct: 144 RGKATEAPKRSALSAGARRDTS-GPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPT 202
Query: 138 EQIRKLMGLLGDNGRKRP-----RRRSPGSGRPQRARRPVPNA----HAPAPSEPDATPL 188
E RK + ++ P RR S G G + A R + ++ +PA S P A
Sbjct: 203 EGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGT 262
Query: 189 PTARDRDADP----TWTLRFSPSPPKSADASPAPGSPPAPAPTALATCIPEDRAPVRGPG 244
P A + P LR P DA+PA G P + +P LAT P + P
Sbjct: 263 PRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALG-PLSSSP--LATPSPSAALQSQAPP 319
Query: 245 SPPPPPAREDPDSPPGRPEDCAPP-PAAPPSLNT 277
+ P P P APP P+APPSL T
Sbjct: 320 TLPATPHSSSLTCQLATPLPLAPPSPSAPPSLQT 353
Score = 53.5 bits (127), Expect = 3e-07
Identities = 82/304 (26%), Positives = 94/304 (30%), Gaps = 61/304 (20%)
Query: 8 PPPLAPPAPPSPASPDPEPRTPGDAPGTPPRRPASPSALGELG-LPVSPGSAQRTPWSAR 66
P PLAPP+P +P S P P P SP+ LP P S TP
Sbjct: 337 PLPLAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATP---- 392
Query: 67 ETELLLGTLLQPAVWRALLLDRRQALPTYRRVSAALAQQQVRRTPAQCRRRYKFLKDKFR 126
P AL L QA P+ S L+ A L+ F
Sbjct: 393 ----------PPQAPPALALPPLQAPPS-PPASPPLSPLATPSPQAPNALAVHLLQAPFS 441
Query: 127 EAHGQP-PGPFDEQIRKLMGLLGDNGRKRPRRRSPGSGRPQRARRPV---PNAHAPAPSE 182
P PF + P P P A P+ P+ A P
Sbjct: 442 PPPSPPVQAPFSPPASPPVS---------PSATPPSQAPPSLAAPPLQVPPSPPASPPMS 492
Query: 183 PDATPLPTARDRDADPTWTLRFSP--------SPPKSADASP-------APGSPPAPAPT 227
P ATP P A A P L P +PP A SP AP SP A P
Sbjct: 493 PSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPM 552
Query: 228 ALATCIPEDRAPVRG------PGSPPPPPAREDPDSPPGRPEDC-----------APPPA 270
+ P PV P SPP P + P PP D AP P
Sbjct: 553 SPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPP 612
Query: 271 APPS 274
PPS
Sbjct: 613 PPPS 616
Score = 51.6 bits (122), Expect = 1e-06
Identities = 76/291 (26%), Positives = 92/291 (31%), Gaps = 31/291 (10%)
Query: 1 MLLRPRRPPPLAPPAPPSPASPDPEPRTPG-------DAPGTPPRRPASPSALGELGLPV 53
+ L P + PP P +PP P P+ P AP +P P SP P
Sbjct: 400 LALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSP---PPSPPVQAPFSPPA 456
Query: 54 SPG-SAQRTPWSARETELLLGTLLQPAVWRA------LLLDRRQALPTYRRVSAALAQQQ 106
SP S TP S L L P A QA P LA+
Sbjct: 457 SPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPP 516
Query: 107 VRRTPAQCRRRYKFLKDKFREAHGQPPGPFDEQIRKLMGLLGDNGRKRPRRRSPGSGRPQ 166
+ PA + L GQ PF M L P + P P
Sbjct: 517 PQAPPALATPPLQALPSPPASFPGQ--APFSPSASLPMSPLA----TPPPQAPPVLAAPL 570
Query: 167 RARRPVPNAHAPAPSEPDATPLPTARDRDADPTWTLRFSPSPPKSADASPAP--GSPPAP 224
P P A +P P P P + P TL +P PP SP+ P
Sbjct: 571 LQVPPSPPA-SPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLA 629
Query: 225 APTALATCIPE-----DRAPVRGPGSPPPPPAREDPDSPPGRPEDCAPPPA 270
++ AT PE D P G + PPP A P APP A
Sbjct: 630 GHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLA 680
Score = 42.7 bits (99), Expect = 5e-04
Identities = 73/275 (26%), Positives = 91/275 (33%), Gaps = 49/275 (17%)
Query: 5 PRRPPPLAPPAPPSPASPDPEPRTPGDAPGTPPRRP---ASPSALGELGLPVS-PGSAQR 60
P PP++P A P P +P P P PP+ P A+P P S PG A
Sbjct: 485 PPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPF 544
Query: 61 TPWSARETELLLGTLLQ-PAVWRALLLDRRQALPTYRRVSAALAQQQVRRTPAQCRRRYK 119
+P ++ L Q P V A LL + P A+ Q RR P
Sbjct: 545 SPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPP------ASPTLQAPRRPPT------- 591
Query: 120 FLKDKFREAHGQPPGPFDEQIRKLMGLLGDNGRKRPRRRSPGS--GRPQRARRPVPNAHA 177
PGP + L G P RSP S P A
Sbjct: 592 -------------PGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATST 638
Query: 178 PA-----PSEPD----ATPLPTARDRDADPTWTLRFSPSPP---KSADASPAPGSPPAPA 225
P S P+ A+P P A P R P+PP + A +P P P
Sbjct: 639 PEELRGYDSGPEGGAAASPPPDAELAACHPAAWSR-GPAPPLAFRGAPGAPLPWPPATGP 697
Query: 226 PTALATCIPEDRAPVRGPGSPPPPPAREDPDSPPG 260
+A C + GP S P P DP PG
Sbjct: 698 GSADGLCTIYE---TEGPESATPAPGALDPGPSPG 729
Score = 42.4 bits (98), Expect = 6e-04
Identities = 80/315 (25%), Positives = 115/315 (36%), Gaps = 67/315 (21%)
Query: 6 RRPPPLAPPAPPSPASPDP---EPRTPGDAPGTPPRRPASPSALGELGLPVSPGSAQRTP 62
+R A A +PA+ P PR PG P PP P +P+AL LG + G+ R P
Sbjct: 4 KRDKAKAGAAARTPAARAPGLLTPRPPGS-PRPPP--PVTPAALRVLG---AAGAVGRKP 57
Query: 63 WSARETELLLGTLLQPAVWRALLLDRRQALPTYRRVSAALAQQQVRRTPAQCRRRYKFLK 122
+ R + T+ + A +A PT R + ++ R PA R
Sbjct: 58 LAERAGGIGGATIPESA---------PRAGPT--RSAGTSSRNPASRPPASGR------G 100
Query: 123 DKFREAHGQPPGPFDEQIR----KLMGLLGDNG--------------RKRPRRRSPGSGR 164
++ A PGP R G LG G + P+R + +G
Sbjct: 101 ERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGA 160
Query: 165 PQRARRPVPNAHAPAPSEPDAT---------PLPTARDRDADPTWTLR---FSPSPPKSA 212
+ P P +PA + P P+AR R PT R S S +
Sbjct: 161 RRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPR--PPTEGPRKSVSSASEHSTT 218
Query: 213 DASPAPGSPPA-------PAPTALATCIPEDRAPVR-GPGSPPPPPAREDPDSP-PGRPE 263
+ SPA P+ PA +L++ +P R GP + P A P P P +
Sbjct: 219 EPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQ 278
Query: 264 DCAPPPAAPPSLNTA 278
PP PP + A
Sbjct: 279 ALRPPQVTPPRKDAA 293
Score = 40.8 bits (94), Expect = 0.002
Identities = 77/298 (25%), Positives = 98/298 (32%), Gaps = 68/298 (22%)
Query: 28 TPGDAPGTPPRRPA--SPSALGELGLP-VSPGSAQRTPWSARETELLLG-----TLLQPA 79
T G PGTP A S +A E+GLP +P + R P + T PA
Sbjct: 164 TSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPA 223
Query: 80 VWRALLLDRRQALPTYRRVSAALAQQQVRRTPAQCRRRYKFLKDKFREAHGQPPGPFDEQ 139
R P R +S++ TP R A G P P
Sbjct: 224 ARRRPSAGGGLQRPASRSLSSSA-------TPLSSPAR------SGPSARGTPRAPAHPS 270
Query: 140 IRKLMGLLGDNGRKRPRRRSPGSGRPQRARRPVPNAHAPAPSEPDATPLPTAR-DRDADP 198
K GL RP + +P R+ A P S P ATP P+A A P
Sbjct: 271 QPKPKGLQA----LRPPQVTP-------PRKDAAPALGPLSSSPLATPSPSAALQSQAPP 319
Query: 199 TWT---------------LRFSPSPPKSADASPAPGSPPAPAPTALATCIPEDR------ 237
T L +P P + + SPPA P+ T +
Sbjct: 320 TLPATPHSSSLTCQLATPLPLAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHS 379
Query: 238 ---APVRGPGSPPPP--------PAREDPDSPPGRP---EDCAPPPAAPPSLNTALLQ 281
+P P + PPP P + P SPP P P P AP +L LLQ
Sbjct: 380 FLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQ 437
Score = 33.1 bits (74), Expect = 0.37
Identities = 30/94 (31%), Positives = 40/94 (42%), Gaps = 14/94 (14%)
Query: 5 PRRPPPLAPPAPPSPA--------SPDPEPRTPGDAPGTPPRRPASPSALGELGLPVSPG 56
P P P P P A + PE TP APG P+ ++ G+ G
Sbjct: 685 PGAPLPWPPATGPGSADGLCTIYETEGPESATP--APGALDPGPSPGTSGGKAAAGAGAG 742
Query: 57 SAQRTPWSARETELLLGTL----LQPAVWRALLL 86
++ R+P AR EL LG L +Q + R LLL
Sbjct: 743 ASSRSPKQARLGELPLGALQASVVQHLLSRTLLL 776
>gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo
sapiens]
Length = 816
Score = 62.0 bits (149), Expect = 7e-10
Identities = 81/300 (27%), Positives = 107/300 (35%), Gaps = 51/300 (17%)
Query: 17 PSPASPDPEPRTPGDAPGT--------PPRRPASPSALGELGLPVSPGSAQRTPWSARET 68
P+P +P P A GT P RP P+ + + + P A
Sbjct: 158 PTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARR 217
Query: 69 ELLLGTLLQPAVWRALLLDRRQALPTYRRVSAALAQQQVRRTPAQCRRRYKFLKDKFREA 128
G LQ R+L A P + + + R PA + R
Sbjct: 218 RPSAGGGLQRPASRSL---SSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPP 274
Query: 129 HGQPPGPFDEQIRKLMGLLGDNGRKRPRRRSPGSGRPQRARRPVPNAHAPAPSEPDATPL 188
PP + +G L + P +P S + + +P+ P ATP
Sbjct: 275 QVTPPR---KDAAPALGPLSSSPLATPSPSAPPSPSAPPSLQTLPS--------PPATPP 323
Query: 189 PTARDRDADPTW--TLRFSPSPPKSADASPAPGSPPA---------PAPTA------LAT 231
A PT T F PSPP S A+P P +PPA P+P A LAT
Sbjct: 324 SQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLAT 383
Query: 232 CIPEDRAP-------VRGPGSPPPPPAREDPDSPPGRP---EDCAPPPAAPPSLNTALLQ 281
P +AP ++ P SPPP P + P SPP P PP APPSL LQ
Sbjct: 384 --PSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQ 441
Score = 60.1 bits (144), Expect = 3e-09
Identities = 54/147 (36%), Positives = 64/147 (43%), Gaps = 21/147 (14%)
Query: 155 PRRRSPGSGRPQRARRPV---PNAHAPAPSEPDATPLPTARDRDADPTWTLRFSP----- 206
P P P A P+ P+ A P P ATP P A + A FSP
Sbjct: 349 PLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPP 408
Query: 207 -----SPPKSADASPAPGSPPAPAPTALATCIPEDRAPVRGPGSPP-PPPAREDPDSPP- 259
SPP S SP+ +PP+ AP +LA P + P P SPP P A P +PP
Sbjct: 409 VQAPFSPPASPPVSPS-ATPPSQAPPSLAA--PPLQVPPSPPASPPMSPSATPPPQAPPP 465
Query: 260 --GRPEDCA-PPPAAPPSLNTALLQTL 283
P A PPP APP+L T LQ L
Sbjct: 466 LAAPPLQLAKPPPQAPPALATPPLQAL 492
Score = 55.5 bits (132), Expect = 7e-08
Identities = 84/310 (27%), Positives = 101/310 (32%), Gaps = 57/310 (18%)
Query: 3 LRPRRPPPLAPPAPPSPASPDPEP--RTPGDAPGTPPRRPASPSALGELGLPVSPGSAQR 60
L P PLA P+P +P SP P +T P TPP + + ++LG L +
Sbjct: 287 LGPLSSSPLATPSPSAPPSPSAPPSLQTLPSPPATPPSQ--ATTSLGSPTLQATHSFLPS 344
Query: 61 TPWSARETELLLGTLLQPAVWRALLLDRRQALPTYRRVSAALAQQQVRRTPAQCRRRYKF 120
P S T P AL L QA P+ S L+ A
Sbjct: 345 PPLSPLATP-------PPQAPPALALPPLQAPPS-PPASPPLSPLATPSPQAPNALAVHL 396
Query: 121 LKDKFREAHGQP-PGPFDEQIRKLMGLLGDNGRKRPRRRSPGSGRPQRARRPV---PNAH 176
L+ F P PF + P P P A P+ P+
Sbjct: 397 LQAPFSPPPSPPVQAPFSPPASPPVS---------PSATPPSQAPPSLAAPPLQVPPSPP 447
Query: 177 APAPSEPDATPLPTARDRDADPTWTLRFSP--------SPPKSADASP-------APGSP 221
A P P ATP P A A P L P +PP A SP AP SP
Sbjct: 448 ASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSP 507
Query: 222 PAPAPTALATCIPEDRAPVRG------PGSPPPPPAREDPDSPPGRPEDC---------- 265
A P + P PV P SPP P + P PP D
Sbjct: 508 SASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLA 567
Query: 266 -APPPAAPPS 274
AP P PPS
Sbjct: 568 LAPGPPPPPS 577
Score = 51.6 bits (122), Expect = 1e-06
Identities = 76/291 (26%), Positives = 92/291 (31%), Gaps = 31/291 (10%)
Query: 1 MLLRPRRPPPLAPPAPPSPASPDPEPRTPG-------DAPGTPPRRPASPSALGELGLPV 53
+ L P + PP P +PP P P+ P AP +P P SP P
Sbjct: 361 LALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSP---PPSPPVQAPFSPPA 417
Query: 54 SPG-SAQRTPWSARETELLLGTLLQPAVWRA------LLLDRRQALPTYRRVSAALAQQQ 106
SP S TP S L L P A QA P LA+
Sbjct: 418 SPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPP 477
Query: 107 VRRTPAQCRRRYKFLKDKFREAHGQPPGPFDEQIRKLMGLLGDNGRKRPRRRSPGSGRPQ 166
+ PA + L GQ PF M L P + P P
Sbjct: 478 PQAPPALATPPLQALPSPPASFPGQ--APFSPSASLPMSPLA----TPPPQAPPVLAAPL 531
Query: 167 RARRPVPNAHAPAPSEPDATPLPTARDRDADPTWTLRFSPSPPKSADASPAP--GSPPAP 224
P P A +P P P P + P TL +P PP SP+ P
Sbjct: 532 LQVPPSPPA-SPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLA 590
Query: 225 APTALATCIPE-----DRAPVRGPGSPPPPPAREDPDSPPGRPEDCAPPPA 270
++ AT PE D P G + PPP A P APP A
Sbjct: 591 GHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLA 641
Score = 48.9 bits (115), Expect = 6e-06
Identities = 84/331 (25%), Positives = 112/331 (33%), Gaps = 79/331 (23%)
Query: 6 RRPPPLAPPAPPSPASPDP---EPRTPGDAPGTPPRRPASPSALGELGLPVSPGSAQRTP 62
+R A A +PA+ P PR PG P PP P +P+AL LG + G+ R P
Sbjct: 4 KRDKAKAGAAARTPAARAPGLLTPRPPGS-PRPPP--PVTPAALRVLG---AAGAVGRKP 57
Query: 63 WSARETELLLGTLLQPAVWRALLLDRRQALPTYRRVSAALAQQQVRRTPAQCRRRYKFLK 122
+ R + T+ + A +A PT R S A + R P +
Sbjct: 58 LAERAGGIGGATIPESA---------PRAGPT--RTSRPPASGRGERAPPAKNTSPGPVS 106
Query: 123 DKFREAHGQPPGPFDEQIRKL----------------MGLLGDNGRKRPRRRSPGSGRPQ 166
R + PGP ++ ++ L R+ +PG+ P
Sbjct: 107 SPGRASGTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPA 166
Query: 167 RAR------------RPVPNAHAPAPSE------------PDATPLPTAR---------- 192
AR RP P+A P+E P P AR
Sbjct: 167 MARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQ 226
Query: 193 ---DRDADPTWTLRFSP--SPPKSADASPAPGSPPAPAPTALATCIPEDRAPVRGPGSPP 247
R + T SP S P + AP P P P L P P R +P
Sbjct: 227 RPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPA 286
Query: 248 PPPAREDPDSPPGRPEDCAPP-PAAPPSLNT 277
P SP P APP P+APPSL T
Sbjct: 287 LGPL---SSSPLATPSPSAPPSPSAPPSLQT 314
Score = 48.5 bits (114), Expect = 8e-06
Identities = 90/337 (26%), Positives = 116/337 (34%), Gaps = 62/337 (18%)
Query: 5 PRRPPPLAPPAPPSPASPDPEPR--------------TPGDAPGTPPRRPASP--SALGE 48
PR PPP+ P A + R P AP P R + P S GE
Sbjct: 33 PRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTRTSRPPASGRGE 92
Query: 49 LGLPV---------SPGSAQRT--PWSARETELLLGTLLQPAVWRALLLDRRQALPTYRR 97
P SPG A T P + L + A +A +R AL R
Sbjct: 93 RAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGAR 152
Query: 98 VSAALAQQQVRRTPAQCRRRYKFLKDKF--REAHGQPPGPFDEQIRKLMGLLGDNGRKRP 155
+ +PA RR + R A P P E RK + ++ P
Sbjct: 153 RDTS-GPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEP 211
Query: 156 -----RRRSPGSGRPQRARRPVPNA----HAPAPSEPDA--TPLPTARDRDADPTWTLRF 204
RR S G G + A R + ++ +PA S P A TP A P
Sbjct: 212 SPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQAL 271
Query: 205 SP---SPPK------------SADASPAPGSPPAP-APTALATCIPEDRAP----VRGPG 244
P +PP+ S A+P+P +PP+P AP +L T P G
Sbjct: 272 RPPQVTPPRKDAAPALGPLSSSPLATPSPSAPPSPSAPPSLQTLPSPPATPPSQATTSLG 331
Query: 245 SPPPPPAREDPDSPPGRPEDCAPPPAAPPSLNTALLQ 281
SP SPP P PPP APP+L LQ
Sbjct: 332 SPTLQATHSFLPSPPLSPL-ATPPPQAPPALALPPLQ 367
Score = 42.7 bits (99), Expect = 5e-04
Identities = 73/275 (26%), Positives = 91/275 (33%), Gaps = 49/275 (17%)
Query: 5 PRRPPPLAPPAPPSPASPDPEPRTPGDAPGTPPRRP---ASPSALGELGLPVS-PGSAQR 60
P PP++P A P P +P P P PP+ P A+P P S PG A
Sbjct: 446 PPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPF 505
Query: 61 TPWSARETELLLGTLLQ-PAVWRALLLDRRQALPTYRRVSAALAQQQVRRTPAQCRRRYK 119
+P ++ L Q P V A LL + P A+ Q RR P
Sbjct: 506 SPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPP------ASPTLQAPRRPPT------- 552
Query: 120 FLKDKFREAHGQPPGPFDEQIRKLMGLLGDNGRKRPRRRSPGS--GRPQRARRPVPNAHA 177
PGP + L G P RSP S P A
Sbjct: 553 -------------PGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATST 599
Query: 178 PA-----PSEPD----ATPLPTARDRDADPTWTLRFSPSPP---KSADASPAPGSPPAPA 225
P S P+ A+P P A P R P+PP + A +P P P
Sbjct: 600 PEELRGYDSGPEGGAAASPPPDAELAACHPAAWSR-GPAPPLAFRGAPGAPLPWPPATGP 658
Query: 226 PTALATCIPEDRAPVRGPGSPPPPPAREDPDSPPG 260
+A C + GP S P P DP PG
Sbjct: 659 GSADGLCTIYE---TEGPESATPAPGALDPGPSPG 690
Score = 33.1 bits (74), Expect = 0.37
Identities = 30/94 (31%), Positives = 40/94 (42%), Gaps = 14/94 (14%)
Query: 5 PRRPPPLAPPAPPSPA--------SPDPEPRTPGDAPGTPPRRPASPSALGELGLPVSPG 56
P P P P P A + PE TP APG P+ ++ G+ G
Sbjct: 646 PGAPLPWPPATGPGSADGLCTIYETEGPESATP--APGALDPGPSPGTSGGKAAAGAGAG 703
Query: 57 SAQRTPWSARETELLLGTL----LQPAVWRALLL 86
++ R+P AR EL LG L +Q + R LLL
Sbjct: 704 ASSRSPKQARLGELPLGALQASVVQHLLSRTLLL 737
>gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens]
Length = 904
Score = 61.6 bits (148), Expect = 1e-09
Identities = 67/282 (23%), Positives = 101/282 (35%), Gaps = 27/282 (9%)
Query: 5 PRRPPPLAPPAPP------SPASPDPEPRTPGDAPGTPPRR------PASPSALGELGLP 52
P + PP +PP SP++ P R P TPP + P + + +
Sbjct: 370 PPKKPPKRTSSPPRKTRRLSPSASPPRRRHRPSPPATPPPKTRHSPTPQQSNRTRKSRVS 429
Query: 53 VSPGSAQRTPWSARETELLLGTLLQPAVWRALLLDRRQALPTYRRVSAALAQQQVRRTPA 112
VSPG + TE P + L + + +++AA + QQ
Sbjct: 430 VSPGRTSGKVTKHKGTEKRESPSPAPKPRKVELSESEE--DKGGKMAAADSVQQ------ 481
Query: 113 QCRRRYKFLKDKFREAHGQPPGPFDEQIRKLMGLLGDNGRKRPRRRSPGSGRPQRARRPV 172
RR+Y+ + G DE+ ++ G+ GR+R S + R R+
Sbjct: 482 --RRQYRRQNQQSSSDSGSSSSSEDERPKRSHVKNGEVGRRRRHSPSRSASPSPRKRQKE 539
Query: 173 PNAHAPAPSEPDATPLPTARDRDADPTWTLRFSPSPPKSADASPAPGSPPAPAPTALATC 232
+ P P R P R +P+PP P +P+P +
Sbjct: 540 TSPRGRRRRSPSPPPTRRRRSPSPAPPPRRRRTPTPPPRRRTPSPPPRRRSPSPRRYSPP 599
Query: 233 IPEDRAPVRGP----GSPPPPPARE-DPDSPPGRPEDCAPPP 269
I +P P SPPPPP R P PP R +PPP
Sbjct: 600 IQRRYSPSPPPKRRTASPPPPPKRRASPSPPPKRRVSHSPPP 641
Score = 56.2 bits (134), Expect = 4e-08
Identities = 76/280 (27%), Positives = 99/280 (35%), Gaps = 67/280 (23%)
Query: 4 RPRRPPPLAPPAPPSPASPDPEPRTPGDAPGTPPRRPASPSALGELGLPVSPGSAQRTPW 63
R PPP PSPA P RTP TPP R +P SP +R+P
Sbjct: 548 RSPSPPPTRRRRSPSPAPPPRRRRTP-----TPPPRRRTP----------SPPPRRRSP- 591
Query: 64 SARETELLLGTLLQPAVWRALLLDRRQALPTYRRVSAALAQQQVRRT----PAQCRRRYK 119
RR + P RR S + + RRT P RR
Sbjct: 592 ----------------------SPRRYSPPIQRRYSPSPPPK--RRTASPPPPPKRRASP 627
Query: 120 FLKDKFREAHGQPPGPFDEQIRKLMGLLGDNGRKRPRRRSPGSGRPQRARRPVPN-AHAP 178
K R +H PP + K + + R+ S S + AR P PN H+P
Sbjct: 628 SPPPKRRVSHSPPPKQRSSPVTKRR---SPSLSSKHRKGSSPSRSTREARSPQPNKRHSP 684
Query: 179 APSEPDATPLPTARDRDADPTWTLRFSPSPPKSADASPAPGSPPAPA--PTALATCIPED 236
+P P A + P P + A +SP P+P+ P + PE
Sbjct: 685 SPR-------PRAPQTSSSP-------PPVRRGASSSPQRRQSPSPSTRPIRRVSRTPEP 730
Query: 237 RAPVRGPGSPPPPPAR--EDPDSPPGRPEDCAPPPAAPPS 274
+ ++ SP P R S G PE A P APPS
Sbjct: 731 K-KIKKAASPSPQSVRRVSSSRSVSGSPEPAAKKPPAPPS 769
Score = 54.3 bits (129), Expect = 2e-07
Identities = 63/233 (27%), Positives = 86/233 (36%), Gaps = 25/233 (10%)
Query: 5 PRRPPPLAPPAPPSPA------------SPDPEPRTPGDAPGTPPRRPASPSALGELGLP 52
PRR P PP SP+ SP P P+ +P PP+R ASPS + +
Sbjct: 577 PRRRTPSPPPRRRSPSPRRYSPPIQRRYSPSPPPKRRTASPPPPPKRRASPSPPPKRRVS 636
Query: 53 VSPGSAQR-TPWSARETELLLGTLLQPAVWRALLLDRRQALPTYRR-VSAALAQQQVRRT 110
SP QR +P + R + L + + + R P R S Q +
Sbjct: 637 HSPPPKQRSSPVTKRRSPSLSSKHRKGSSPSRSTREARSPQPNKRHSPSPRPRAPQTSSS 696
Query: 111 PAQCRRRYKFLKDKFREAHGQPPGPFDEQIRKLMGLLGDNGRKRPRRRSPGSGRPQRARR 170
P RR + Q P P IR++ K+ SP S R + R
Sbjct: 697 PPPVRRGASSSPQR-----RQSPSPSTRPIRRVSRTPEPKKIKKAASPSPQSVRRVSSSR 751
Query: 171 PVPNAHAPAPSEPDATPLPTARDRDADPTWTLRFSPSPPKSADASPAPG-SPP 222
V + PA +P A P P + + W SP+ P SP P SPP
Sbjct: 752 SVSGSPEPAAKKPPAPPSP-VQSQSPSTNW----SPAVPVKKAKSPTPSPSPP 799
Score = 44.7 bits (104), Expect = 1e-04
Identities = 42/127 (33%), Positives = 54/127 (42%), Gaps = 7/127 (5%)
Query: 152 RKRPRRRSPGSGRPQRARRPVPNAHAPA--PSEPDATPLPTARD--RDADPTWTLRFSPS 207
R R R RSP RP+R R +++P PS P P P R R P R S S
Sbjct: 285 RSRTRSRSPSHTRPRRRHRSRSRSYSPRRRPS-PRRRPSPRRRTPPRRMPPPPRHRRSRS 343
Query: 208 PPKSADASPAPGSPPAPAPTALATCIPEDRAPVRGPGSPPPPPAREDPD-SPPGRPEDCA 266
P + S A S + + ++ + P + P R SPP R P SPP R +
Sbjct: 344 PVRRRRRSSASLSGSSSSSSSSRSRSPPKKPPKR-TSSPPRKTRRLSPSASPPRRRHRPS 402
Query: 267 PPPAAPP 273
PP PP
Sbjct: 403 PPATPPP 409
Score = 32.3 bits (72), Expect = 0.63
Identities = 25/104 (24%), Positives = 38/104 (36%), Gaps = 13/104 (12%)
Query: 152 RKRPRRRSPGSGRPQRARRPVPNAHAPAPSEPDATPLPTARDRDADPTWTLRFSPSPPKS 211
R+ P RR P R +R+R PV + S ++ ++ + P + + SPP+
Sbjct: 325 RRTPPRRMPPPPRHRRSRSPVRRRRRSSASLSGSSSSSSSSRSRSPPKKPPKRTSSPPRK 384
Query: 212 ADASPAPGSPPAPAPTALATCIPEDRAPVRGPGSPPPPPAREDP 255
SPP R P + PPP R P
Sbjct: 385 TRRLSPSASPPR-------------RRHRPSPPATPPPKTRHSP 415
>gi|7706501 WW domain binding protein 11 [Homo sapiens]
Length = 641
Score = 59.3 bits (142), Expect = 5e-09
Identities = 39/128 (30%), Positives = 49/128 (38%), Gaps = 8/128 (6%)
Query: 152 RKRPRRRSPGSGRPQRARRPVPNAHAPAPSEPDATPLPTARDRDADPTWTLRFSPSPPKS 211
+K+ + S G + + + PS+ A P+P P LR P PP
Sbjct: 371 QKQHKEESHSDGTSTASSQQQAPPQSVPPSQIQAPPMPGPPPLGPPPAPPLR-PPGPPTG 429
Query: 212 ADASPAPGSPPAPAPTA-------LATCIPEDRAPVRGPGSPPPPPAREDPDSPPGRPED 264
P PG+PP P L +P P R PG PP PP P PP P
Sbjct: 430 LPPGPPPGAPPFLRPPGMPGLRGPLPRLLPPGPPPGRPPGPPPGPPPGLPPGPPPRGPPP 489
Query: 265 CAPPPAAP 272
PPPA P
Sbjct: 490 RLPPPAPP 497
Score = 42.7 bits (99), Expect = 5e-04
Identities = 35/108 (32%), Positives = 36/108 (33%), Gaps = 5/108 (4%)
Query: 169 RRPVPNAHAPAPSEPDATPL--PTARDRDADPTWTLRFSPSPPKSADASPAPGSPPAPAP 226
R P P P P A P P P L P PP P PG PP P
Sbjct: 422 RPPGPPTGLPPGPPPGAPPFLRPPGMPGLRGPLPRL-LPPGPPPGRPPGPPPGPPPGLPP 480
Query: 227 TALATCIPEDRAPVRGPGSPPPPPAREDPDSPPGRPEDCAPPPAAPPS 274
P P PG PPP P P P P APP PP+
Sbjct: 481 GPPPRGPPPRLPPPAPPGIPPPRPGMMRPPLVP--PLGPAPPGLFPPA 526
Score = 40.4 bits (93), Expect = 0.002
Identities = 29/77 (37%), Positives = 30/77 (38%), Gaps = 19/77 (24%)
Query: 3 LRPRRPPPLAPPAPPSPASPDPEP------RTPGD-----------APGTPPRRPASPSA 45
L P PPL PP PP+ P P P R PG PG PP RP P
Sbjct: 413 LGPPPAPPLRPPGPPTGLPPGPPPGAPPFLRPPGMPGLRGPLPRLLPPGPPPGRPPGPPP 472
Query: 46 LGELGLPVSPGSAQRTP 62
GLP PG R P
Sbjct: 473 GPPPGLP--PGPPPRGP 487
Score = 39.7 bits (91), Expect = 0.004
Identities = 24/58 (41%), Positives = 25/58 (43%), Gaps = 3/58 (5%)
Query: 8 PPPLA-PPAPPSPASPDPEPRTPGDAPGTPP--RRPASPSALGELGLPVSPGSAQRTP 62
PPPL PPAPP P PG PG PP R P P G L + PG P
Sbjct: 410 PPPLGPPPAPPLRPPGPPTGLPPGPPPGAPPFLRPPGMPGLRGPLPRLLPPGPPPGRP 467
Score = 37.0 bits (84), Expect = 0.025
Identities = 27/66 (40%), Positives = 28/66 (42%), Gaps = 12/66 (18%)
Query: 2 LLRPRRPP---PLAPPAPPSPASPDPEPR------TPGDAPGTPPRRPA--SPSALGELG 50
LL P PP P PP PP P P PR P PG PP RP P + LG
Sbjct: 457 LLPPGPPPGRPPGPPPGPPPGLPPGPPPRGPPPRLPPPAPPGIPPPRPGMMRPPLVPPLG 516
Query: 51 LPVSPG 56
P PG
Sbjct: 517 -PAPPG 521
Score = 36.6 bits (83), Expect = 0.033
Identities = 28/88 (31%), Positives = 28/88 (31%), Gaps = 24/88 (27%)
Query: 3 LRPRRPPPLAPPAPPSPASP---------------------DPEPRTPGDAPGTPPRRPA 41
LRP PP PP PP A P P R PG PG PP P
Sbjct: 421 LRPPGPPTGLPPGPPPGAPPFLRPPGMPGLRGPLPRLLPPGPPPGRPPGPPPGPPPGLPP 480
Query: 42 SPSALG---ELGLPVSPGSAQRTPWSAR 66
P G L P PG P R
Sbjct: 481 GPPPRGPPPRLPPPAPPGIPPPRPGMMR 508
Score = 33.9 bits (76), Expect = 0.22
Identities = 19/51 (37%), Positives = 23/51 (45%), Gaps = 4/51 (7%)
Query: 216 PAPGSPPAPAPTALATCIPEDRA----PVRGPGSPPPPPAREDPDSPPGRP 262
P PG+ P + P RA P+ G G P PP R+ P PPG P
Sbjct: 157 PLPGAQPPSILKKTSAYGPPTRAVSILPLLGHGVPRLPPGRKPPGPPPGPP 207
Score = 33.9 bits (76), Expect = 0.22
Identities = 25/63 (39%), Positives = 28/63 (44%), Gaps = 7/63 (11%)
Query: 5 PRRPPPL---APPAP-PSPASPDPEP--RTPGDAPGTPP-RRPASPSALGELGLPVSPGS 57
P+ PP APP P P P P P P R PG G PP P +P L G+P G
Sbjct: 394 PQSVPPSQIQAPPMPGPPPLGPPPAPPLRPPGPPTGLPPGPPPGAPPFLRPPGMPGLRGP 453
Query: 58 AQR 60
R
Sbjct: 454 LPR 456
Score = 32.0 bits (71), Expect = 0.82
Identities = 17/37 (45%), Positives = 17/37 (45%)
Query: 3 LRPRRPPPLAPPAPPSPASPDPEPRTPGDAPGTPPRR 39
L P R PP PP PP P R G A PPRR
Sbjct: 193 LPPGRKPPGPPPGPPPPQVVQMYGRKVGFALDLPPRR 229
Score = 31.2 bits (69), Expect = 1.4
Identities = 22/58 (37%), Positives = 23/58 (39%), Gaps = 8/58 (13%)
Query: 5 PRRPPPLAPPAPPSPASPDPEPRTPGDAPGTPPRRPASPSALGELGLPVSPGSAQRTP 62
PR PPP P PP P P P P PP PA P LP +PG P
Sbjct: 489 PRLPPPAPPGIPP----PRPGMMRP---PLVPPLGPAPPGLFPPAPLP-NPGVLSAPP 538
Score = 28.9 bits (63), Expect = 6.9
Identities = 17/50 (34%), Positives = 21/50 (42%), Gaps = 5/50 (10%)
Query: 6 RRPPPLAPPAPPSPASPDPEPRTPGDAPGTPPRRPASPSALGELGLPVSP 55
++ PP + P A P P P G P P R P P+ GLP P
Sbjct: 390 QQAPPQSVPPSQIQAPPMPGPPPLGPPPAPPLRPPGPPT-----GLPPGP 434
>gi|163965366 nascent polypeptide-associated complex alpha subunit
isoform a [Homo sapiens]
Length = 2078
Score = 58.9 bits (141), Expect = 6e-09
Identities = 79/289 (27%), Positives = 101/289 (34%), Gaps = 62/289 (21%)
Query: 8 PPPLAPPAPP-SPAS---PDPEPRTPGDAPGTPPRRPASPSALGELGLPVSPGSAQRTPW 63
PP PP+P SPA+ P P TP +P PA+PS G P P + +P
Sbjct: 1035 PPAATPPSPKGSPAATPLPKGAPTTPAATLPSPKGGPATPSLKGA---PTPPAATPPSPK 1091
Query: 64 SARETELLLGTLLQPAVWRALLLDRRQALPTYRRVSAALAQQQVRRTPAQCRRRYKFLKD 123
T G + PA P+ + A + TPA
Sbjct: 1092 GGPATPSPKGAPMPPAA----------TPPSPKGGLATPPHKGAPTTPA----------- 1130
Query: 124 KFREAHGQPPGPFDEQIRKLMGLLGDNGRKRPRRRSPGSGR------PQRARRPVPNAHA 177
PP P + + G +P S + P + P A
Sbjct: 1131 ------ATPPSP-----KGGLATPPPKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATP 1179
Query: 178 PAPSEPDATPLPTARDRDADPTWTLRFSPSPPKSADASPAP-GSPPAPAPT------ALA 230
P+P ATP P PT T +P PK A+P+P G+P PA T LA
Sbjct: 1180 PSPKGGLATPSPKGA-----PT-TPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLA 1233
Query: 231 TCIPEDRAPVRGPGSPPPPPAREDPDSPPGRPEDCAPPPAAPPSLNTAL 279
T P+ AP +PP P P G P PP A PPSL L
Sbjct: 1234 TPSPKG-APTTPAATPPSPKGGPATPPPKGAP---TPPAATPPSLKGGL 1278
Score = 57.4 bits (137), Expect = 2e-08
Identities = 76/280 (27%), Positives = 101/280 (36%), Gaps = 55/280 (19%)
Query: 5 PRRPPPLAPPA-PPSP----ASPDPE--PRTPGDAPGTPPRRPASPSALGELGLPVSPGS 57
P + P P A PPSP A+P P+ P TP P +P A+P G P +P +
Sbjct: 1121 PHKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPPPKGA---PTTPAA 1177
Query: 58 AQRTPWSARETELLLGTLLQPAVWRALLLDRRQALPTYRRVSAALAQQQVRRTPAQCRRR 117
+P T G PA P+ + A + + TPA
Sbjct: 1178 TPPSPKGGLATPSPKGAPTTPAA----------TPPSPKGGLATPSPKGAPTTPA----- 1222
Query: 118 YKFLKDKFREAHGQPPGPFDEQIRKLMGLLGDNGRKRPRRRSPGSGRPQRARRPVPNAHA 177
PP P GL + + P +P + P P
Sbjct: 1223 ------------ATPPSPKG-------GLATPSPKGAPT--TPAATPPSPKGGPATPPPK 1261
Query: 178 PAPSEPDATPLPTARDRDADPTWTLRFSPSPPKSADASPAPG---SPPAPAPTALATCIP 234
AP+ P ATP P+ + A P + +P+P SP G SPP APT A P
Sbjct: 1262 GAPTPPAATP-PSLKGGLATPPH--KGAPNPAVVTPPSPKGGPATSPPKGAPTPPAATPP 1318
Query: 235 EDRAPVRGPGSPPPPPAREDPDSPPGRPEDCAPPPAAPPS 274
+P PG+PPP A P P P+ PA PS
Sbjct: 1319 ---SPKGSPGTPPPKGAPTPPAVTPPSPKGTPTLPATTPS 1355
Score = 56.2 bits (134), Expect = 4e-08
Identities = 76/299 (25%), Positives = 120/299 (40%), Gaps = 39/299 (13%)
Query: 9 PPLAPPAP---PSPASPDPEPRTPGDAPGTPPRRPASP--------SALGELGLP-VSPG 56
P + PP+P P+ SP +P +P P +P + PA+P + G+L P V+P
Sbjct: 1382 PAMTPPSPKRGPAIPSPKGDPTSPAVIPLSPKKAPATPVTREGAATPSKGDLTPPAVTPV 1441
Query: 57 SAQRTPWSARE-----TELLLGTLLQPAVWRALLLDRRQALPTYRRVSAALAQQQVRRTP 111
S ++ P ++ T G PAV + P ++V+ + + ++ TP
Sbjct: 1442 SLKKAPATSAPKGGPATPSSKGDPTLPAVTPP----SPKEPPAPKQVATSSSPKKAPATP 1497
Query: 112 AQCRRRY--KFLKDKFREAHGQPPGPFDEQIRKLMGLLGDNGRKRPRRRSPGSGR-PQRA 168
A + +E P D I LL +K P +P P
Sbjct: 1498 APMGAPTLPAVIPSSPKEVPATPSSRRDP-IAPTATLLS---KKTPATLAPKEALIPPAM 1553
Query: 169 RRPVPNAHAPAPSEPDATPLPTARDRDADPTWT---LRFSPSPPKSADASPAPGSP-PAP 224
P P P+ +A P++++ + P T + +PSP K PA SP P
Sbjct: 1554 TVPSPKKTPAIPTPKEAPATPSSKEASSPPAVTPSTYKGAPSP-KELLIPPAVTSPSPKE 1612
Query: 225 APTALATCIPEDRAPVRGPGSPPPPPAREDPDSPPGRPEDCAPPPAAPPSLNTALLQTL 283
APT A P +P +GP +P P + P SPP P P +P S+ + T+
Sbjct: 1613 APTPPAVTPP---SPEKGPATPAP---KGTPTSPPVTPSSLKDSPTSPASVTCKMGATV 1665
Score = 55.8 bits (133), Expect = 5e-08
Identities = 83/304 (27%), Positives = 108/304 (35%), Gaps = 53/304 (17%)
Query: 8 PPPLAPPAPPSP-ASPDPEPRTPGDAPGT--PPRRPASPSALGELGLPVSPGSAQRTPWS 64
P P PPSP +P P TP G PP+ +PS + LP P TP +
Sbjct: 850 PATTHSPTPPSPKGAPTPSAVTPLSPKGVTLPPKETPTPSVVN---LPF-PKEGPATP-A 904
Query: 65 ARETELLLGTLLQPAVWRALLLDRRQALPTYRRVSAALAQQQVRRTPAQCRRRYKFLKDK 124
++ L T P + +A P + + A+ + + PA K
Sbjct: 905 PKQAPALSMTSSSPK--------KARATPAPKGIPASPSPKGAPTPPAATPPSPK----- 951
Query: 125 FREAHGQPPGPFDEQIRKLMGLLGDNGRKRPRRRSP-GSGRPQRARRPVPNAHAPAPSEP 183
G P P + + + P SP G+ P A P P PA P
Sbjct: 952 -----GGPATPSPKWAPTPPAATPPSPKGGPATPSPKGAPTPPAATPPSPKG-GPATPSP 1005
Query: 184 DATPLPTARDRDADPTWTLRFSPSP----------PKSADASPAPGSPPAPAPTALATCI 233
P P A + P + +P P P S SPA P APT A +
Sbjct: 1006 KGAPTPPAVTPPS-PKGSPAATPFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATL 1064
Query: 234 PEDRAPVRGPGSP-----PPPPAREDPDSPPGRPEDCAP-----PPAAPPSLNTALLQTL 283
P +P GP +P P PPA P SP G P +P PPAA P L T
Sbjct: 1065 P---SPKGGPATPSLKGAPTPPAA-TPPSPKGGPATPSPKGAPMPPAATPPSPKGGLATP 1120
Query: 284 GHLG 287
H G
Sbjct: 1121 PHKG 1124
Score = 55.1 bits (131), Expect = 9e-08
Identities = 78/279 (27%), Positives = 109/279 (39%), Gaps = 51/279 (18%)
Query: 17 PSPASPDPEPRTPGDAPGTPPRRPASPSALGELGLPVSPGSAQRTPWSARETELLLGTLL 76
PSP P+T P T + +G L PVSP A P ++ + G+
Sbjct: 794 PSPLGVSVSPQTK--RPPTKKGSAGPDTPIGNLSSPVSPVEASFLPENSLSFQ---GSKD 848
Query: 77 QPAVWRALLLDRRQALPTYRRVSAALAQQQV----RRTPAQCRRRYKFLKDKFREAHGQP 132
PA + + PT V+ L+ + V + TP F K+ P
Sbjct: 849 SPATTHSPTPPSPKGAPTPSAVTP-LSPKGVTLPPKETPTPSVVNLPFPKEG-------P 900
Query: 133 PGPFDEQIRKLMGLLGDNGRKRPRRRSPGSGRPQRARRPVPNAHAP--APSEPDATPLPT 190
P +Q L SP R A + +P + +P AP+ P ATP P+
Sbjct: 901 ATPAPKQAPALS----------MTSSSPKKARATPAPKGIPASPSPKGAPTPPAATP-PS 949
Query: 191 ARDRDADPTWTLRFSPSPPKSADASP--APGSP-PAPAPTALATCIPEDRAPVRGPGSPP 247
+ A P+ +++P+PP + SP P +P P APT A P +P GP +P
Sbjct: 950 PKGGPATPS--PKWAPTPPAATPPSPKGGPATPSPKGAPTPPAATPP---SPKGGPATPS 1004
Query: 248 P-----PPAREDPDSPPGRPE-------DCAPPPAAPPS 274
P PPA P SP G P PP A PPS
Sbjct: 1005 PKGAPTPPA-VTPPSPKGSPAATPFPKGASTPPAATPPS 1042
Score = 55.1 bits (131), Expect = 9e-08
Identities = 72/285 (25%), Positives = 95/285 (33%), Gaps = 57/285 (20%)
Query: 8 PPPLAPPAPPSPASPDPE----PRTPGDAPGTPPRRPASP----SALGELGLPVSPGSAQ 59
PPP P P+ P P+ P AP TP P SP + G P +P +
Sbjct: 1143 PPPKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATP 1202
Query: 60 RTPWSARETELLLGTLLQPAVWRALLLDRRQALPTYRRVSAALAQQQVRRTPAQCRRRYK 119
+P T G PA P+ + A + + TPA K
Sbjct: 1203 PSPKGGLATPSPKGAPTTPAA----------TPPSPKGGLATPSPKGAPTTPAATPPSPK 1252
Query: 120 FLKDKFREAHGQPPGPFDEQIRKLMGLLGDNGRKRPRRRSPGSGRPQRARRPVPNAHAPA 179
G P P G P +P S + A P A PA
Sbjct: 1253 ----------GGPATP------------PPKGAPTPPAATPPSLKGGLATPPHKGAPNPA 1290
Query: 180 PSEPDATPLPTARDRDADPTWTLRFSPSPPKSADASP--APGSPP---APAPTALATCIP 234
P P P + P + +P+PP + SP +PG+PP AP P A+ P
Sbjct: 1291 VVTP---PSPKGGPATSPP----KGAPTPPAATPPSPKGSPGTPPPKGAPTPPAVTPPSP 1343
Query: 235 E--DRAPVRGP---GSPPPPPAREDPDSPPGRPEDCAPPPAAPPS 274
+ P P G P P ++E P P P P PPS
Sbjct: 1344 KGTPTLPATTPSSKGGPTTPSSKEGPTPPAATPSHKGGPAMTPPS 1388
Score = 50.4 bits (119), Expect = 2e-06
Identities = 73/292 (25%), Positives = 104/292 (35%), Gaps = 40/292 (13%)
Query: 8 PPPLAPPAP-------PSPASPDPEPRTPGDAPGTPPRRPASPSALGELGLPVSPGSAQ- 59
PP PP+P P +P P TP GTP +PS+ G P +P S +
Sbjct: 1312 PPAATPPSPKGSPGTPPPKGAPTPPAVTPPSPKGTPTLPATTPSSKGG---PTTPSSKEG 1368
Query: 60 RTPWSARETELLLGTLLQPAVWRALLLDRRQALPTYRRVSAALAQQQVRRTPAQCRRRYK 119
TP +A + + P+ R + + PT S A+ ++ PA R
Sbjct: 1369 PTPPAATPSHKGGPAMTPPSPKRGPAIPSPKGDPT----SPAVIPLSPKKAPATPVTREG 1424
Query: 120 FLKDKFREAHGQPPGPFDEQIRKLMGLLGDNG-------RKRPRRRSPGSGRPQRARRPV 172
+ PP ++K G + P + P+ P
Sbjct: 1425 AATPS--KGDLTPPAVTPVSLKKAPATSAPKGGPATPSSKGDPTLPAVTPPSPKEPPAPK 1482
Query: 173 PNAHAPAPSEPDATPLPTARDRDADPTWTLRFSPSPPKSADASPAPGSPP-APAPTAL-- 229
A + +P + ATP P PT PS PK A+P+ P AP T L
Sbjct: 1483 QVATSSSPKKAPATPAPMGA-----PTLP-AVIPSSPKEVPATPSSRRDPIAPTATLLSK 1536
Query: 230 ---ATCIPEDR--APVRGPGSPPPPPAREDPDSPPGRP--EDCAPPPAAPPS 274
AT P++ P SP PA P P P ++ + PPA PS
Sbjct: 1537 KTPATLAPKEALIPPAMTVPSPKKTPAIPTPKEAPATPSSKEASSPPAVTPS 1588
Score = 49.7 bits (117), Expect = 4e-06
Identities = 72/290 (24%), Positives = 98/290 (33%), Gaps = 55/290 (18%)
Query: 5 PRRPPPLAPPAPPSP----ASPDPE--PRTPGDAPGTPPRRPASPSALGELGLPVSPGSA 58
P+ P PPSP A+P P+ P TP P +P A+PS G P +P +
Sbjct: 1191 PKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGA---PTTPAAT 1247
Query: 59 QRTPWSARETELLLGTLLQPAVWRALLLDRRQALPTYRRVS--AALAQQQVRRTPAQCRR 116
+P T G PA L A P ++ A + + PA
Sbjct: 1248 PPSPKGGPATPPPKGAPTPPAATPPSLKGGL-ATPPHKGAPNPAVVTPPSPKGGPATSPP 1306
Query: 117 RYKFLKDKFREAHGQPPGPFDEQIRKLMGLLGDNGRKRPRRRSPGSGRPQRARRPVPNAH 176
K PP P + SPG+ P+ A P P
Sbjct: 1307 -----KGAPTPPAATPPSP---------------------KGSPGTPPPKGAPTP-PAVT 1339
Query: 177 APAPSEPDATPLPTARDRDADPTWTLRFSPSPPKSADASPAPGSPPAPAPTALATCIPED 236
P+P P T + T + + P+PP A+P+ PA P +
Sbjct: 1340 PPSPKGTPTLPATTPSSKGGPTTPSSKEGPTPPA---ATPSHKGGPAMTPPS-------- 1388
Query: 237 RAPVRGPGSPPPPPAREDPDSPPGRPEDCAPPPAAPPSLNTALLQTLGHL 286
P RGP P P + DP SP P PA P + A + G L
Sbjct: 1389 --PKRGPAIPSP---KGDPTSPAVIPLSPKKAPATPVTREGAATPSKGDL 1433
Score = 45.8 bits (107), Expect = 5e-05
Identities = 78/311 (25%), Positives = 101/311 (32%), Gaps = 52/311 (16%)
Query: 5 PRRPPPLA---PPA--PPSPASPDPEPRTPGDAPGTPPRRPASPSALGELGLPVSPGSAQ 59
P PPP PPA PPSP P T + G P + P G
Sbjct: 1324 PGTPPPKGAPTPPAVTPPSPKGTPTLPATTPSSKGGPTTPSSKEGPTPPAATPSHKGGPA 1383
Query: 60 RTPWSARETELL---LGTLLQPAVWRALLLDRRQALPTYRRVSAALAQQQVRR---TPAQ 113
TP S + + G PAV L + A P R +A ++ + TP
Sbjct: 1384 MTPPSPKRGPAIPSPKGDPTSPAV-IPLSPKKAPATPVTREGAATPSKGDLTPPAVTPVS 1442
Query: 114 CRRRYKFLKDKFREAHGQPPGPFDEQIRKLMGLLGDNGRKRPRRR------SPGSGRPQR 167
++ K G P P + L + + ++ P + SP
Sbjct: 1443 LKKAPATSAPK-----GGPATPSSKGDPTLPAVTPPSPKEPPAPKQVATSSSPKKAPATP 1497
Query: 168 ARRPVPNAHAPAPSEPDATP-LPTARDRDADPTWTLRFSPSP------------------ 208
A P A PS P P P++R PT TL +P
Sbjct: 1498 APMGAPTLPAVIPSSPKEVPATPSSRRDPIAPTATLLSKKTPATLAPKEALIPPAMTVPS 1557
Query: 209 PKSADASPAPGSPPAPAPTALATCIPEDRAPVRGPGSPPP-----PPAREDPDSPPGRPE 263
PK A P P PA P++ P P G+P P PPA P SP P
Sbjct: 1558 PKKTPAIPTPKEAPA-TPSSKEASSPPAVTPSTYKGAPSPKELLIPPAVTSP-SPKEAP- 1614
Query: 264 DCAPPPAAPPS 274
PP PPS
Sbjct: 1615 --TPPAVTPPS 1623
Score = 41.2 bits (95), Expect = 0.001
Identities = 70/273 (25%), Positives = 97/273 (35%), Gaps = 44/273 (16%)
Query: 8 PPPLAPPAP---PSPASPDPEPRTPGDAPGTPPRRPASPSALGELGLPVSPGSAQRTPWS 64
PP + P+P P+P + P G A P P SP PV+P S + +P S
Sbjct: 1602 PPAVTSPSPKEAPTPPAVTPPSPEKGPATPAPKGTPTSP--------PVTPSSLKDSPTS 1653
Query: 65 ARETELLLGTLLQPAVWRALLLDRRQALPTYRRVSAALAQQQVRRTPAQCRRRYKFLKDK 124
+G + A + L ++ + V A A + A R+ + K
Sbjct: 1654 PASVTCKMGATVPQA---SKGLPAKKGPTALKEVLVAPAPESTPIITAPTRKGPQTKK-- 1708
Query: 125 FREAHGQPPGPFDEQIRKLMGLLGDNGRKRPRRRSPGSGRPQRARRPVPNAHAP----AP 180
+ PP D + G G P P + + +H+P AP
Sbjct: 1709 --SSATSPPICPDPSAKN--GSKGPLSTVAPAPLLPVQKDSSKTAKGKDASHSPKGPLAP 1764
Query: 181 SEPDA-TPLPTARDRDADPTWTLRFSPSPPKSADASPAPGSPPAP---APTALATCIPED 236
E A TPL A P P+SA S AP SPP AP+ + T P+
Sbjct: 1765 PESKASTPLTAAAFEKVLP---------KPESASVSAAP-SPPVSLPLAPSPVPTLPPKQ 1814
Query: 237 RAPVRGPG------SPPPPPAREDPDSPPGRPE 263
+ PG S P PA ED P PE
Sbjct: 1815 QFLPSSPGLVLESPSKPLAPADEDELLPLIPPE 1847
Score = 33.5 bits (75), Expect = 0.28
Identities = 35/141 (24%), Positives = 49/141 (34%), Gaps = 23/141 (16%)
Query: 155 PRRRSPGSGRPQRARRPVPNAH----APAPSEPDATPLP-TARDRDADPTWTLRF---SP 206
P P +G P ++ +H AP S P P + A TL + SP
Sbjct: 735 PSPSLPPAGTPPGTKKVDGISHTSALAPVASSPKECPTEDSGASATASSKGTLTYLADSP 794
Query: 207 SP-----------PKSADASPAPGSP----PAPAPTALATCIPEDRAPVRGPGSPPPPPA 251
SP P + S P +P +P A+ +PE+ +G P
Sbjct: 795 SPLGVSVSPQTKRPPTKKGSAGPDTPIGNLSSPVSPVEASFLPENSLSFQGSKDSPATTH 854
Query: 252 REDPDSPPGRPEDCAPPPAAP 272
P SP G P A P +P
Sbjct: 855 SPTPPSPKGAPTPSAVTPLSP 875
Score = 29.3 bits (64), Expect = 5.3
Identities = 64/290 (22%), Positives = 89/290 (30%), Gaps = 42/290 (14%)
Query: 5 PRRPPPLAPPAPPSP------ASPDPEPRTPGDAPGTPPRRPASPSALGELGLPVSPGSA 58
P PPP +P P ASP P P T P P P + LP+ G+A
Sbjct: 43 PTLPPPCSPAPQQCPLSAANQASPFPSPSTIASTPLEVP----FPQSSSGTALPL--GTA 96
Query: 59 QRTPWSARETELLLGTLLQPAVWRALLLDRRQALPTYRRV-SAALAQQQVRRTPAQCRRR 117
P L+G + PA AL L PT + S++ V P ++
Sbjct: 97 PEAPTFLPN---LIGPPISPA---ALALASPMIAPTLKGTPSSSAPLALVALAPHSVQKS 150
Query: 118 YKFLKDKFREAHGQPPGPFDEQIRKLMGLLGDNGRKRPR---RRSPGSGRPQRARRPVPN 174
F + PP + ++ L P+ + P P P P
Sbjct: 151 SAFPPNLLT----SPPSVAVAESGSVITLSAPIAPSEPKTNLNKVPSEVVPNPKGTPSPP 206
Query: 175 AHAPAPSEPDATPLPTARDRDAD-----PTWTLRFSPSPPKSADASPAPGSPPAPAPTAL 229
TP+ + + A PT TL + K S SP P +L
Sbjct: 207 CIVSTVPYHCVTPMASIQSGVASLPQTTPTTTLAIASPQVKDTTISSVLISPQNPGSLSL 266
Query: 230 ATCIPEDRAPVRGPGSPPPPPAREDPDSPPGRPEDCAPPPAAPPSLNTAL 279
+GP SPP + P P PP +L
Sbjct: 267 -----------KGPVSPPAALSLSTQSLPVVTSSQKTAGPNTPPDFPISL 305
>gi|112734870 hypothetical protein LOC57648 [Homo sapiens]
Length = 1094
Score = 58.5 bits (140), Expect = 8e-09
Identities = 83/328 (25%), Positives = 109/328 (33%), Gaps = 98/328 (29%)
Query: 12 APPAPPSPASPDPEPRTPGDA--PGTPPRRPASPSA-------------LGELGLPVSPG 56
A P PP+PA+ +PG + P P R SPS+ G G P SPG
Sbjct: 547 AAPCPPNPANSWVPGLSPGGSRRPPRSPERTLSPSSGYSSQSGTPTLPPKGLAGPPASPG 606
Query: 57 SAQRTPWSARETELLLGTLLQPAVWRALLLDRRQALPTYRRVSAALAQQQVRRTPAQCRR 116
AQ P R T +L P VS++L + C
Sbjct: 607 KAQ-PPKPERVT-----SLRSPGA----------------SVSSSLT--------SLC-- 634
Query: 117 RYKFLKDKFREAHGQPPGPFDEQIRKLMGLLGDNGRKRPRRRSPGSGRPQRARRPVPNAH 176
+ P P D +++ LGD P + P P ++ PN
Sbjct: 635 -----------SSSSDPAPSDRSGPQILTPLGDRFVIPPHPKVPAPFSPPPSKPRSPNPA 683
Query: 177 APAPSEPDATPLP---TARDRDADPTWTLRFSP---SPPKSADASPAPGSPPAPAPTALA 230
APA + P P P T + PT +P SP S D SP P PP+ P
Sbjct: 684 APALAAPAVVPGPVSTTDASPQSPPTPQTTLTPLQESPVISKDQSPPPSPPPSYHPPPPP 743
Query: 231 TCIPE-----------DRAPVRGPGSPPPPP-----------------------AREDPD 256
T PE P++ P PPPPP A +P
Sbjct: 744 TKKPEVVVEAPSASETAEEPLQDPNWPPPPPPAPEEQDLSMADFPPPEEAFFSVASPEPA 803
Query: 257 SPPGRPEDCAPPPAAPPSLNTALLQTLG 284
P G PE + P A+ S +Q G
Sbjct: 804 GPSGSPELVSSPAASSSSATALQIQPPG 831
Score = 33.9 bits (76), Expect = 0.22
Identities = 65/290 (22%), Positives = 87/290 (30%), Gaps = 43/290 (14%)
Query: 9 PPLAPPAPPSPASPDPEPRTPGDAPGTPPRRPASPSALGELGLPVSPGSAQRTPWSARET 68
PP +P PP+P +P P PG P + P S G G P A
Sbjct: 829 PPGSPDPPPAPPAPAPASSAPGHVAKLPQKEPVGCSKGG--GPPREDVGA---------- 876
Query: 69 ELLLGTLLQPAVWRALLLDRRQALPTYRRVSAALAQQQVRRTPAQCRRRYKFLKDKFREA 128
L+ +LLQ R++ P + + Q+ +RR L +
Sbjct: 877 PLVTPSLLQMVRLRSVGAPGGAPTPA---LGPSAPQKPLRRA----------LSGRASPV 923
Query: 129 HGQPPGPFDEQIRKLMGLLGDNGRKRPRRRSPGSGRPQRARRPVPNAH--APAPSEPDAT 186
G K L G + P P+ + P A S
Sbjct: 924 PAPSSGLHAAVRLKACSLAASEGLSSAQPNGPPEAEPRPPQSPASTASFIFSKGSRKLQL 983
Query: 187 PLPTARDRDADPTWTLRFSPSPPKSADASPAP-GSPPAPAPTALATCIPEDRAPVRGPGS 245
P + + AD L AP SP AP P A R P
Sbjct: 984 ERPVSPETQADLQRNLVAELRSISEQRPPQAPKKSPKAPPPVA------------RKPSV 1031
Query: 246 PPPPPAREDPDSPPGRPEDCAPPPAAPPSLNTALLQTLGHLGDIANILGP 295
PPPA P P P APP P + L G + ++GP
Sbjct: 1032 GVPPPA--SPSYPRAEPL-TAPPTNGLPHTQDRTKRELAENGGVLQLVGP 1078
Score = 31.6 bits (70), Expect = 1.1
Identities = 24/75 (32%), Positives = 30/75 (40%), Gaps = 9/75 (12%)
Query: 5 PRRPPPLAP------PAPPSPASPDPEPRTPGDAPGTPPRRPASPSALGELG---LPVSP 55
P+ PPP+A P P SP+ P EP T G P + + L E G V P
Sbjct: 1019 PKAPPPVARKPSVGVPPPASPSYPRAEPLTAPPTNGLPHTQDRTKRELAENGGVLQLVGP 1078
Query: 56 GSAQRTPWSARETEL 70
P S + EL
Sbjct: 1079 EEKMGLPGSDSQKEL 1093
Score = 28.5 bits (62), Expect = 9.1
Identities = 37/140 (26%), Positives = 49/140 (35%), Gaps = 16/140 (11%)
Query: 148 GDNGRKRPRRRSPGSGRPQRARRPV---PNAHAP----APSEPDATPLPTARDRDADPTW 200
G +GR+R RRS G PQ ++ + AP AP DA +PT D P
Sbjct: 209 GKSGRRRRERRSTVLGLPQHVQKELGLRNEREAPGTPRAPGARDAVRIPTV---DGRPRG 265
Query: 201 TLRFSPSPPKSADASPAPGSPPAPAPTALATCIP----EDRAPVRGPGSPPPPPAREDPD 256
T S A A A L I +D R G+ PP R
Sbjct: 266 TSGMGAR--VSLQALEAEAEAGAETEAMLQRHIDRVYRDDTFVGRSTGTRAPPLTRPMSL 323
Query: 257 SPPGRPEDCAPPPAAPPSLN 276
+ PG P P+++
Sbjct: 324 AVPGLTGGAGPAEPLSPAMS 343
>gi|39930517 sterile alpha motif domain containing 1 [Homo sapiens]
Length = 538
Score = 58.5 bits (140), Expect = 8e-09
Identities = 69/251 (27%), Positives = 87/251 (34%), Gaps = 30/251 (11%)
Query: 33 PGTPPRRPASPSALGELGLPVSPGSAQRTPWSARETELLLGTLLQPAVWRALLLDRRQAL 92
P PP A+ +A S S W + L +P + R + RR+
Sbjct: 5 PALPPPETAA-AATTAAAASSSAASPHYQEWILDTIDSLRSRKARPDLERICRMVRRRHG 63
Query: 93 PTYRRVSAALAQQQVRRTPAQCRRRYKFLKDKFREAHGQPPGPFDEQIRKLMGLLGDNGR 152
P R A L + +R A R YK A QPP G
Sbjct: 64 PEPERTRAELEKLIQQR--AVLRVSYKGSISYRNAARVQPPR---------RGATPPAPP 112
Query: 153 KRPRRRSPGSGRPQRARRPVPNAHAPAPSEPDATPLPTARDRDADPTWTLRFSPSP---- 208
+ PR G+ A P P P P P A P R A T SP P
Sbjct: 113 RAPR----GAPAAAAAAAPPPTPAPPPPPAPVAAAAPARAPRAAAAAATAPPSPGPAQPG 168
Query: 209 PKSADASP------APGSPPAPAPTALATCIPEDRAPVRGPGSPPPPPAREDPDSPPGRP 262
P++ A+P AP +PPA AP A P R P PPPP P +PP +
Sbjct: 169 PRAQRAAPLAAPPPAPAAPPAVAPPAGPRRAPPPAVAAREPPLPPPP----QPPAPPQQQ 224
Query: 263 EDCAPPPAAPP 273
+ P P PP
Sbjct: 225 QPPPPQPQPPP 235
Score = 40.4 bits (93), Expect = 0.002
Identities = 30/82 (36%), Positives = 39/82 (47%), Gaps = 12/82 (14%)
Query: 206 PSPPKS------ADASPAPGSPPA----PAPTALATCIPEDRAPVRGPGSPPPP-PARED 254
P+PP++ A A+ AP PA PAP A A RA +PP P PA+
Sbjct: 109 PAPPRAPRGAPAAAAAAAPPPTPAPPPPPAPVAAAAPARAPRAAAAAATAPPSPGPAQPG 168
Query: 255 PDSPPGRPEDCAPP-PAAPPSL 275
P + P PP PAAPP++
Sbjct: 169 PRAQRAAPLAAPPPAPAAPPAV 190
Score = 38.5 bits (88), Expect = 0.009
Identities = 27/69 (39%), Positives = 29/69 (42%), Gaps = 5/69 (7%)
Query: 5 PRRPPPLAPPAPPSPASPDPEPRTPGDAPGTPPRRPASPSALGELGLPVSPGSAQRTPWS 64
PRR PP A A P P P+P P PP +P P G V G A R P S
Sbjct: 196 PRRAPPPAVAAREPPLPPPPQPPAPPQQQQPPPPQPQPPPE----GGAVRAGGAAR-PVS 250
Query: 65 ARETELLLG 73
RE LG
Sbjct: 251 LREVVRYLG 259
Score = 37.7 bits (86), Expect = 0.015
Identities = 26/68 (38%), Positives = 29/68 (42%), Gaps = 4/68 (5%)
Query: 4 RPRRPPPLAPPAPPSPASPDPEPRTPGDAP-GTPPRRPASPSALGELGLPVSPGSAQRTP 62
R R A APPSP P PR AP PP PA+P A+ P P A
Sbjct: 147 RAPRAAAAAATAPPSPGPAQPGPRAQRAAPLAAPPPAPAAPPAVAP---PAGPRRAPPPA 203
Query: 63 WSARETEL 70
+ARE L
Sbjct: 204 VAAREPPL 211
Score = 36.2 bits (82), Expect = 0.043
Identities = 25/68 (36%), Positives = 29/68 (42%), Gaps = 7/68 (10%)
Query: 5 PRRPPPLAPPA--PPSPASPDPEPRTPGDAPGTPPRRPASPSALGELGLPVSPGSAQRTP 62
PR P A A PP+PA P P AP PR A+ + P SPG AQ P
Sbjct: 115 PRGAPAAAAAAAPPPTPAPPPPPAPVAAAAPARAPRAAAAAAT-----APPSPGPAQPGP 169
Query: 63 WSARETEL 70
+ R L
Sbjct: 170 RAQRAAPL 177
Score = 33.9 bits (76), Expect = 0.22
Identities = 21/60 (35%), Positives = 26/60 (43%), Gaps = 2/60 (3%)
Query: 5 PRRPPPLAPPAPPSPASPDPEPRTPGDAPGTPPR-RPASPSALGELGLPV-SPGSAQRTP 62
P P P PPAP + A+P PR A PP PA P + P+ +P A P
Sbjct: 128 PPTPAPPPPPAPVAAAAPARAPRAAAAAATAPPSPGPAQPGPRAQRAAPLAAPPPAPAAP 187
Score = 32.0 bits (71), Expect = 0.82
Identities = 23/53 (43%), Positives = 27/53 (50%), Gaps = 8/53 (15%)
Query: 4 RPRRPPPLAPPAPPSPASPDPEPRTPGDAPGTPPRRPASPS-ALGELGLPVSP 55
R +R PLA P PP+PA+P P AP PRR P+ A E LP P
Sbjct: 170 RAQRAAPLAAP-PPAPAAP------PAVAPPAGPRRAPPPAVAAREPPLPPPP 215
Score = 30.8 bits (68), Expect = 1.8
Identities = 25/72 (34%), Positives = 27/72 (37%), Gaps = 11/72 (15%)
Query: 8 PPPLAPPAPPSPASP--DPEPRTPGDAPGTPPRRPASPSALGELGLPVSP-------GSA 58
P P APPA PA P P P P PP P P A + P P G A
Sbjct: 182 PAPAAPPAVAPPAGPRRAPPPAVAAREPPLPP--PPQPPAPPQQQQPPPPQPQPPPEGGA 239
Query: 59 QRTPWSARETEL 70
R +AR L
Sbjct: 240 VRAGGAARPVSL 251
>gi|150170670 piccolo isoform 2 [Homo sapiens]
Length = 4935
Score = 57.8 bits (138), Expect = 1e-08
Identities = 71/286 (24%), Positives = 100/286 (34%), Gaps = 56/286 (19%)
Query: 14 PAPPSPASPDPEPRTPGDAPGTPP----------RRPASPSALGELGLPVSPGSAQ---R 60
P+ PSP+ P + TPG P P + PA PS L + L PG+ + +
Sbjct: 296 PSLPSPSKPPIQQPTPGKPPAQQPGHEKSQPGPAKPPAQPSGLTK-PLAQQPGTVKPPVQ 354
Query: 61 TPWSARETELLLGTLLQPAVWRALLLDRRQALPTYRRVSAALAQQQ-VRRTPAQCRRRYK 119
P + + LG PA + + + ALAQ V +TPAQ
Sbjct: 355 PPGTTKPPAQPLGPAKPPAQQTG-----SEKPSSEQPGPKALAQPPGVGKTPAQ------ 403
Query: 120 FLKDKFREAHGQPPGPFDEQIRKLMGLLGDNGRKRPRRRSPGSGRPQRARRPVPN-AHAP 178
PGP +++ G +P + PG P +A P P
Sbjct: 404 ------------QPGPAKPPTQQV-------GTPKPLAQQPGLQSPAKAPGPTKTPVQQP 444
Query: 179 APSEPDATPLPTARD--RDADPTWTLRFSPSPPKSADASPAPGSPPAPAPTALATCIPED 236
P + A + + PT P P K P P PP P +
Sbjct: 445 GPGKIPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSA------- 497
Query: 237 RAPVRGPGSPPPPPAREDPDSP-PGRPEDCAPPPAAPPSLNTALLQ 281
+ P + PGS PPP + P P P +P PP P S + Q
Sbjct: 498 KPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQ 543
Score = 49.7 bits (117), Expect = 4e-06
Identities = 67/293 (22%), Positives = 109/293 (37%), Gaps = 37/293 (12%)
Query: 5 PRRPPPLAPPAPPSPASPDPEPRTPGDAPGT--PPRRPASPSALGELGLPVSPGSAQRTP 62
P R P P S +S PE + PGT P + P LP+ +++
Sbjct: 225 PGRDPLQQDGTPKSISSQQPE-KIKSQPPGTGKPIQGPTQTPQTDHAKLPLQRDASRP-- 281
Query: 63 WSARETELLLGTLLQPAV---WRALLLDRRQALPTYRRVSAALAQQQVRRTPAQCRRRYK 119
++ +++ G ++P++ + + P ++ +Q + PAQ K
Sbjct: 282 -QTKQADIVRGESVKPSLPSPSKPPIQQPTPGKPPAQQPGHEKSQPGPAKPPAQPSGLTK 340
Query: 120 FLKDKFREAHG--QPPGPFDEQIRKLMGLLGDNGRKRPRRRSPGSGRPQRARRPVPNAHA 177
L + QPPG + L G +P + GS +P + +P P A A
Sbjct: 341 PLAQQPGTVKPPVQPPGTTKPPAQPL-------GPAKPPAQQTGSEKPS-SEQPGPKALA 392
Query: 178 ------------PAPSEPDATPLPTARDRDADP-TWTLRFSPSPPKSADASPAPGSPPA- 223
P P++P + T + P + +P P K+ P PG PA
Sbjct: 393 QPPGVGKTPAQQPGPAKPPTQQVGTPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQ 452
Query: 224 ---PAPTALATCIPEDRAPVRGPGSPPPPPAREDPDSPPGRPEDCAPPPAAPP 273
P T+ P + P + PG PPP + P PP + A PP+ P
Sbjct: 453 QAGPGKTSAQQTGPT-KPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQP 504
Score = 47.0 bits (110), Expect = 2e-05
Identities = 46/165 (27%), Positives = 62/165 (37%), Gaps = 22/165 (13%)
Query: 131 QPPGPFDEQIRKLMGLLGDNGRKRP---------RRRSPGSGRPQRARRPVPNA-HAPAP 180
QPP P +Q L +G + + + PG+G+P + P HA P
Sbjct: 214 QPPKPIPKQQGPGRDPLQQDGTPKSISSQQPEKIKSQPPGTGKPIQGPTQTPQTDHAKLP 273
Query: 181 SEPDATPLPTARDRDADPTWTLRFS-PSPPKSADASPAPGSPPAPAPTALATCIPEDRAP 239
+ DA+ P + D +++ S PSP K P PG PPA P E P
Sbjct: 274 LQRDASR-PQTKQADIVRGESVKPSLPSPSKPPIQQPTPGKPPAQQPGH------EKSQP 326
Query: 240 VRGPGSPPPPPAREDPDSPPGRPEDCAPPPAAPPSLNTALLQTLG 284
GP PP P+ P + PP PP Q LG
Sbjct: 327 --GPAKPPAQPS--GLTKPLAQQPGTVKPPVQPPGTTKPPAQPLG 367
Score = 46.6 bits (109), Expect = 3e-05
Identities = 69/294 (23%), Positives = 102/294 (34%), Gaps = 40/294 (13%)
Query: 5 PRRPPPLAPPA--PPS--PASPDPEPRTPGDA------PGT---PPRRPASPSALGELGL 51
P +PPP P + PPS P S P P+ PG A PG+ P ++P S +
Sbjct: 486 PAKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQPS 545
Query: 52 PVSPGSAQRTPWSARETELLLGTLLQP-AVWRALLLDRRQALP-------TYRRVSAALA 103
P P + Q T ++ G LQP V + Q LP + +
Sbjct: 546 PAKPSAQQSTKPVSQTGS---GKPLQPPTVSPSAKQPPSQGLPKTICPLCNTTELLLHVP 602
Query: 104 QQQVRRTPAQCRRRYKFLKDKFREAHGQPPGPFDEQIRKLMGLLGDNGRKRPRRRSPGSG 163
++ T +C+ L G P P ++++ + L R +P
Sbjct: 603 EKANFNTCTECQTTVCSLC-------GFNPNPHLTEVKEWLCLNCQMKRALGGDLAPVPS 655
Query: 164 RPQRARRPVPNAHAPAPSEPDATPLPTARDRDADPTWTLRFSPSPPKSADASPAP---GS 220
PQ + P A S+ P T+ +DA P L +P P K P GS
Sbjct: 656 SPQPKLKTAPVTTTSAVSKSSPQPQQTSPKKDAAPKQDLSKAPEPKKPPPLVKQPTLHGS 715
Query: 221 PPAPAPTALATCIPEDRAPVRGPGSPPPPPAREDPDSPPGRPEDCAPPPAAPPS 274
P A A P + + P P P + D P + P P+
Sbjct: 716 PSAKAKQ------PPEADSLSKPAPPKEPSVPSEQDKAPVADDKPKQPKMVKPT 763
Score = 37.4 bits (85), Expect = 0.019
Identities = 21/60 (35%), Positives = 26/60 (43%), Gaps = 1/60 (1%)
Query: 215 SPAPGSPPA-PAPTALATCIPEDRAPVRGPGSPPPPPAREDPDSPPGRPEDCAPPPAAPP 273
SP+ S PA P P ++ + P P PPPPP P PP P +P P P
Sbjct: 2380 SPSVSSLPAKPRPFFRSSSLDISAQPPPPPPPPPPPPPPPPPPPPPPLPPPTSPKPTILP 2439
Score = 37.0 bits (84), Expect = 0.025
Identities = 72/279 (25%), Positives = 102/279 (36%), Gaps = 43/279 (15%)
Query: 8 PPPLAPPAPPSPASPDP-EPRTPGDAPGTPPRRPASPSALGELGLPVSPGSAQRT--PWS 64
PP A PS + P E +P D+ P RPAS S + P S Q+ P
Sbjct: 793 PPLKTDSAKPSQSFPPTGEKVSPFDSKAIP--RPASDSKIISHPGPSSESKGQKQVDPVQ 850
Query: 65 ARETELLLGTLLQPAVWRALLLDRRQALPTYRRVSAA--LAQQQVRRTPAQCRRRYKFLK 122
+E T + P A + + P R +A + Q P + RR+
Sbjct: 851 KKEEPKKAQTKMSPKP-DAKPMPKGSPTPPGPRPTAGQTVPTPQQSPKPQEQSRRFSLNL 909
Query: 123 DKFREA-HGQPPGPFDEQIRKLMG-----------LLGDNGRKRPRRRSPGSGRPQRARR 170
+A QP P + KL G L+ G+ P +S G G P +
Sbjct: 910 GSITDAPKSQPTTPQETVTGKLFGFGASIFSQASNLISTAGQPGPHSQS-GPGAPMK--- 965
Query: 171 PVPNAHAPAPSEPDATPLPTARDRDADPTWTLRFSPSPPKSADASPAPGSPPAPAPTALA 230
APAPS+P PT++ P T + P+P KS P APA L
Sbjct: 966 -----QAPAPSQP-----PTSQ---GPPKSTGQAPPAPAKSI---PVKKETKAPAAEKLE 1009
Query: 231 TCIPEDRAP-VRGPGSPPPPPAREDPDSPPGRPEDCAPP 268
++AP V+ + PP +D S P+ P
Sbjct: 1010 P--KAEQAPTVKRTETEKKPPPIKDSKSLTAEPQKAVLP 1046
Score = 36.6 bits (83), Expect = 0.033
Identities = 20/56 (35%), Positives = 24/56 (42%), Gaps = 5/56 (8%)
Query: 7 RPPPLAPPAPPSPASPDPEPRTPGDAPGTPPRRPASPSALGELGLPVSPGSAQRTP 62
+PPP PP PP P P P P P PP P+ L + L V+ TP
Sbjct: 2404 QPPPPPPPPPPPPPPPPPPP-----PPPLPPPTSPKPTILPKKKLTVASPVTTATP 2454
Score = 36.2 bits (82), Expect = 0.043
Identities = 62/290 (21%), Positives = 109/290 (37%), Gaps = 34/290 (11%)
Query: 5 PRRPPPLAPPAPPSPASPDPEPRTPGDAPG----TPPRRPASPSALGELGLPVSPGSAQR 60
P++PPPL P SP + + P +A PP+ P+ PS + PV+ ++
Sbjct: 700 PKKPPPLVKQ-PTLHGSPSAKAKQPPEADSLSKPAPPKEPSVPSEQDKA--PVADDKPKQ 756
Query: 61 TPWSARETELLLGT--LLQPAVWRALLLDRRQ--ALPTYRRVSAALAQQ----QVRRTPA 112
T+L+ + +P + + + + + P + SA +Q + +P
Sbjct: 757 PKMVKPTTDLVSSSSATTKPDIPSSKVQSQAEEKTTPPLKTDSAKPSQSFPPTGEKVSPF 816
Query: 113 QCRRRYKFLKDKFREAHGQPPGPFDEQIRKLMGLLGDNGRKRPRRRSPGSGRPQRARRPV 172
+ + D +H PGP E K + +K +++ P+ +P+
Sbjct: 817 DSKAIPRPASDSKIISH---PGPSSES--KGQKQVDPVQKKEEPKKAQTKMSPKPDAKPM 871
Query: 173 PNAHAPAPSEPDATP---LPTARDRDADPTWTLRFSPSPPKSADASPAPGSPPAPAPTAL 229
P +P P P T +PT + + RFS + DA + + P T
Sbjct: 872 PKG-SPTPPGPRPTAGQTVPTPQQSPKPQEQSRRFSLNLGSITDAPKSQPTTPQETVTGK 930
Query: 230 -----ATCIPEDRAPVRGPGSPPPPPAREDPDSPPGRPEDCAPPPAAPPS 274
A+ + + G P P S PG P AP P+ PP+
Sbjct: 931 LFGFGASIFSQASNLISTAGQPGP-----HSQSGPGAPMKQAPAPSQPPT 975
Score = 35.4 bits (80), Expect = 0.074
Identities = 14/30 (46%), Positives = 16/30 (53%)
Query: 4 RPRRPPPLAPPAPPSPASPDPEPRTPGDAP 33
+P PPP PP PP P P P P P +P
Sbjct: 2404 QPPPPPPPPPPPPPPPPPPPPPPLPPPTSP 2433
Score = 35.4 bits (80), Expect = 0.074
Identities = 20/64 (31%), Positives = 26/64 (40%)
Query: 9 PPLAPPAPPSPASPDPEPRTPGDAPGTPPRRPASPSALGELGLPVSPGSAQRTPWSARET 68
PP PP PP P P P P P P T P+ P + PV+ + + ET
Sbjct: 2405 PPPPPPPPPPPPPPPPPPPPPPLPPPTSPKPTILPKKKLTVASPVTTATPLFDAVTTLET 2464
Query: 69 ELLL 72
+L
Sbjct: 2465 TAVL 2468
Score = 33.5 bits (75), Expect = 0.28
Identities = 63/297 (21%), Positives = 88/297 (29%), Gaps = 82/297 (27%)
Query: 5 PRRPPPLAP-PAPPSPASPDPE---PRTPGDAPGTPPRRPASPSALGELGLPVSPGSAQR 60
P +PP P PA P P P P P+ PG A P ++P S P PG A+
Sbjct: 466 PTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAK-PPSQQPGSTKPP-----PQQPGPAKP 519
Query: 61 TPWSARETELLLGTLLQPAVWRALLLDRRQALPTYRRVSAALAQQQVRRTPAQCRRRYKF 120
+P T+ P+ + SA + QQ
Sbjct: 520 SPQQPGSTKP----------------------PSQQPGSAKPSAQQP------------- 544
Query: 121 LKDKFREAHGQPPGPFDEQIRKLMGLLGDNGRKRPRRRSPGSGRPQ-----RARRPVPNA 175
P P +Q K + G +P SP + +P + P+ N
Sbjct: 545 ----------SPAKPSAQQSTKPVSQTGSGKPLQPPTVSPSAKQPPSQGLPKTICPLCNT 594
Query: 176 HAPAPSEPDATPLPTARDRDADPTWTLRFSPSPPKS-----------------ADASPAP 218
P+ T + F+P+P + D +P P
Sbjct: 595 TELLLHVPEKANFNTCTECQTTVCSLCGFNPNPHLTEVKEWLCLNCQMKRALGGDLAPVP 654
Query: 219 GSPPAPAPTALATCIPEDRAPVRGPGSPPPPPAREDPDSPPGRPEDCAPPPAAPPSL 275
SP TA P SP P D+ P + AP P PP L
Sbjct: 655 SSPQPKLKTA-----PVTTTSAVSKSSPQPQQTSPKKDAAPKQDLSKAPEPKKPPPL 706
Score = 33.5 bits (75), Expect = 0.28
Identities = 45/177 (25%), Positives = 60/177 (33%), Gaps = 51/177 (28%)
Query: 135 PFDEQIRKLMGLLGDN-GRKRPRRRSPGSGRPQRARRPVPNAHAPAPSEPDATPLPTARD 193
P EQ+ G+ G+++P + P SG P + + P++P ++ D
Sbjct: 2351 PMKEQLSTTYFTSGETFGQEKPASQLP-SGSP---------SVSSLPAKPRPFFRSSSLD 2400
Query: 194 RDADPTWTLRFSPSPPKSADASPAPGSPPAPAPTA----------------LATCIP--- 234
A P P PP P P PP P PT+ + T P
Sbjct: 2401 ISAQPPPP---PPPPPPPPPPPPPPPPPPLPPPTSPKPTILPKKKLTVASPVTTATPLFD 2457
Query: 235 -----EDRAPVRGPGSP-------PPPPAREDPDSPPG------RPEDCAPPPAAPP 273
E A +R G P PPP P S P RPE PP A P
Sbjct: 2458 AVTTLETTAVLRSNGLPVTRICTTAPPPVPPKPSSIPSGLVFTHRPEPSKPPIAPKP 2514
Score = 33.5 bits (75), Expect = 0.28
Identities = 25/89 (28%), Positives = 39/89 (43%), Gaps = 5/89 (5%)
Query: 174 NAHAPAPSEPDATPLPTARDRDADPTWTLRFSPSPPKSADASPAPGSPPAPAPTALATCI 233
+A +P + TPL T++ +PSPPKS +P SP +P + +
Sbjct: 3582 SATSPPKDKKRPTPLEIGYSSHLRADSTVQLAPSPPKSPKVLYSPISPLSPGKALESAFV 3641
Query: 234 PEDRAPVRGPGSPP----PPPAREDPDSP 258
P ++ P+ SP P A+ P SP
Sbjct: 3642 PYEK-PLPDDISPQKVLHPDMAKVPPASP 3669
Score = 33.1 bits (74), Expect = 0.37
Identities = 13/33 (39%), Positives = 16/33 (48%)
Query: 243 PGSPPPPPAREDPDSPPGRPEDCAPPPAAPPSL 275
P PPPPP P PP P PP + P++
Sbjct: 2405 PPPPPPPPPPPPPPPPPPPPPPLPPPTSPKPTI 2437
Score = 33.1 bits (74), Expect = 0.37
Identities = 14/35 (40%), Positives = 16/35 (45%)
Query: 5 PRRPPPLAPPAPPSPASPDPEPRTPGDAPGTPPRR 39
P PPP PP PP P P P P P P++
Sbjct: 2407 PPPPPPPPPPPPPPPPPPPPLPPPTSPKPTILPKK 2441
Score = 30.4 bits (67), Expect = 2.4
Identities = 22/71 (30%), Positives = 26/71 (36%), Gaps = 6/71 (8%)
Query: 204 FSPSPPKSADASPAPGSPPAPAPTALATCIPEDRAPVRGPGSPPPPPAREDPDSPPGRPE 263
F P S S +P PA P R+ + PPPP P PP P
Sbjct: 2367 FGQEKPASQLPSGSPSVSSLPAKPR-----PFFRSSSLDISAQPPPPPPPPPPPPPPPPP 2421
Query: 264 DCAPPPAAPPS 274
PPP PP+
Sbjct: 2422 P-PPPPLPPPT 2431
>gi|150378539 piccolo isoform 1 [Homo sapiens]
Length = 5142
Score = 57.8 bits (138), Expect = 1e-08
Identities = 71/286 (24%), Positives = 100/286 (34%), Gaps = 56/286 (19%)
Query: 14 PAPPSPASPDPEPRTPGDAPGTPP----------RRPASPSALGELGLPVSPGSAQ---R 60
P+ PSP+ P + TPG P P + PA PS L + L PG+ + +
Sbjct: 296 PSLPSPSKPPIQQPTPGKPPAQQPGHEKSQPGPAKPPAQPSGLTK-PLAQQPGTVKPPVQ 354
Query: 61 TPWSARETELLLGTLLQPAVWRALLLDRRQALPTYRRVSAALAQQQ-VRRTPAQCRRRYK 119
P + + LG PA + + + ALAQ V +TPAQ
Sbjct: 355 PPGTTKPPAQPLGPAKPPAQQTG-----SEKPSSEQPGPKALAQPPGVGKTPAQ------ 403
Query: 120 FLKDKFREAHGQPPGPFDEQIRKLMGLLGDNGRKRPRRRSPGSGRPQRARRPVPN-AHAP 178
PGP +++ G +P + PG P +A P P
Sbjct: 404 ------------QPGPAKPPTQQV-------GTPKPLAQQPGLQSPAKAPGPTKTPVQQP 444
Query: 179 APSEPDATPLPTARD--RDADPTWTLRFSPSPPKSADASPAPGSPPAPAPTALATCIPED 236
P + A + + PT P P K P P PP P +
Sbjct: 445 GPGKIPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSA------- 497
Query: 237 RAPVRGPGSPPPPPAREDPDSP-PGRPEDCAPPPAAPPSLNTALLQ 281
+ P + PGS PPP + P P P +P PP P S + Q
Sbjct: 498 KPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQ 543
Score = 49.7 bits (117), Expect = 4e-06
Identities = 67/293 (22%), Positives = 109/293 (37%), Gaps = 37/293 (12%)
Query: 5 PRRPPPLAPPAPPSPASPDPEPRTPGDAPGT--PPRRPASPSALGELGLPVSPGSAQRTP 62
P R P P S +S PE + PGT P + P LP+ +++
Sbjct: 225 PGRDPLQQDGTPKSISSQQPE-KIKSQPPGTGKPIQGPTQTPQTDHAKLPLQRDASRP-- 281
Query: 63 WSARETELLLGTLLQPAV---WRALLLDRRQALPTYRRVSAALAQQQVRRTPAQCRRRYK 119
++ +++ G ++P++ + + P ++ +Q + PAQ K
Sbjct: 282 -QTKQADIVRGESVKPSLPSPSKPPIQQPTPGKPPAQQPGHEKSQPGPAKPPAQPSGLTK 340
Query: 120 FLKDKFREAHG--QPPGPFDEQIRKLMGLLGDNGRKRPRRRSPGSGRPQRARRPVPNAHA 177
L + QPPG + L G +P + GS +P + +P P A A
Sbjct: 341 PLAQQPGTVKPPVQPPGTTKPPAQPL-------GPAKPPAQQTGSEKPS-SEQPGPKALA 392
Query: 178 ------------PAPSEPDATPLPTARDRDADP-TWTLRFSPSPPKSADASPAPGSPPA- 223
P P++P + T + P + +P P K+ P PG PA
Sbjct: 393 QPPGVGKTPAQQPGPAKPPTQQVGTPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQ 452
Query: 224 ---PAPTALATCIPEDRAPVRGPGSPPPPPAREDPDSPPGRPEDCAPPPAAPP 273
P T+ P + P + PG PPP + P PP + A PP+ P
Sbjct: 453 QAGPGKTSAQQTGPT-KPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQP 504
Score = 47.0 bits (110), Expect = 2e-05
Identities = 46/165 (27%), Positives = 62/165 (37%), Gaps = 22/165 (13%)
Query: 131 QPPGPFDEQIRKLMGLLGDNGRKRP---------RRRSPGSGRPQRARRPVPNA-HAPAP 180
QPP P +Q L +G + + + PG+G+P + P HA P
Sbjct: 214 QPPKPIPKQQGPGRDPLQQDGTPKSISSQQPEKIKSQPPGTGKPIQGPTQTPQTDHAKLP 273
Query: 181 SEPDATPLPTARDRDADPTWTLRFS-PSPPKSADASPAPGSPPAPAPTALATCIPEDRAP 239
+ DA+ P + D +++ S PSP K P PG PPA P E P
Sbjct: 274 LQRDASR-PQTKQADIVRGESVKPSLPSPSKPPIQQPTPGKPPAQQPGH------EKSQP 326
Query: 240 VRGPGSPPPPPAREDPDSPPGRPEDCAPPPAAPPSLNTALLQTLG 284
GP PP P+ P + PP PP Q LG
Sbjct: 327 --GPAKPPAQPS--GLTKPLAQQPGTVKPPVQPPGTTKPPAQPLG 367
Score = 46.6 bits (109), Expect = 3e-05
Identities = 69/294 (23%), Positives = 102/294 (34%), Gaps = 40/294 (13%)
Query: 5 PRRPPPLAPPA--PPS--PASPDPEPRTPGDA------PGT---PPRRPASPSALGELGL 51
P +PPP P + PPS P S P P+ PG A PG+ P ++P S +
Sbjct: 486 PAKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQPS 545
Query: 52 PVSPGSAQRTPWSARETELLLGTLLQP-AVWRALLLDRRQALP-------TYRRVSAALA 103
P P + Q T ++ G LQP V + Q LP + +
Sbjct: 546 PAKPSAQQSTKPVSQTGS---GKPLQPPTVSPSAKQPPSQGLPKTICPLCNTTELLLHVP 602
Query: 104 QQQVRRTPAQCRRRYKFLKDKFREAHGQPPGPFDEQIRKLMGLLGDNGRKRPRRRSPGSG 163
++ T +C+ L G P P ++++ + L R +P
Sbjct: 603 EKANFNTCTECQTTVCSLC-------GFNPNPHLTEVKEWLCLNCQMKRALGGDLAPVPS 655
Query: 164 RPQRARRPVPNAHAPAPSEPDATPLPTARDRDADPTWTLRFSPSPPKSADASPAP---GS 220
PQ + P A S+ P T+ +DA P L +P P K P GS
Sbjct: 656 SPQPKLKTAPVTTTSAVSKSSPQPQQTSPKKDAAPKQDLSKAPEPKKPPPLVKQPTLHGS 715
Query: 221 PPAPAPTALATCIPEDRAPVRGPGSPPPPPAREDPDSPPGRPEDCAPPPAAPPS 274
P A A P + + P P P + D P + P P+
Sbjct: 716 PSAKAKQ------PPEADSLSKPAPPKEPSVPSEQDKAPVADDKPKQPKMVKPT 763
Score = 37.4 bits (85), Expect = 0.019
Identities = 21/60 (35%), Positives = 26/60 (43%), Gaps = 1/60 (1%)
Query: 215 SPAPGSPPA-PAPTALATCIPEDRAPVRGPGSPPPPPAREDPDSPPGRPEDCAPPPAAPP 273
SP+ S PA P P ++ + P P PPPPP P PP P +P P P
Sbjct: 2380 SPSVSSLPAKPRPFFRSSSLDISAQPPPPPPPPPPPPPPPPPPPPPPLPPPTSPKPTILP 2439
Score = 37.0 bits (84), Expect = 0.025
Identities = 72/279 (25%), Positives = 102/279 (36%), Gaps = 43/279 (15%)
Query: 8 PPPLAPPAPPSPASPDP-EPRTPGDAPGTPPRRPASPSALGELGLPVSPGSAQRT--PWS 64
PP A PS + P E +P D+ P RPAS S + P S Q+ P
Sbjct: 793 PPLKTDSAKPSQSFPPTGEKVSPFDSKAIP--RPASDSKIISHPGPSSESKGQKQVDPVQ 850
Query: 65 ARETELLLGTLLQPAVWRALLLDRRQALPTYRRVSAA--LAQQQVRRTPAQCRRRYKFLK 122
+E T + P A + + P R +A + Q P + RR+
Sbjct: 851 KKEEPKKAQTKMSPKP-DAKPMPKGSPTPPGPRPTAGQTVPTPQQSPKPQEQSRRFSLNL 909
Query: 123 DKFREA-HGQPPGPFDEQIRKLMG-----------LLGDNGRKRPRRRSPGSGRPQRARR 170
+A QP P + KL G L+ G+ P +S G G P +
Sbjct: 910 GSITDAPKSQPTTPQETVTGKLFGFGASIFSQASNLISTAGQPGPHSQS-GPGAPMK--- 965
Query: 171 PVPNAHAPAPSEPDATPLPTARDRDADPTWTLRFSPSPPKSADASPAPGSPPAPAPTALA 230
APAPS+P PT++ P T + P+P KS P APA L
Sbjct: 966 -----QAPAPSQP-----PTSQ---GPPKSTGQAPPAPAKSI---PVKKETKAPAAEKLE 1009
Query: 231 TCIPEDRAP-VRGPGSPPPPPAREDPDSPPGRPEDCAPP 268
++AP V+ + PP +D S P+ P
Sbjct: 1010 P--KAEQAPTVKRTETEKKPPPIKDSKSLTAEPQKAVLP 1046
Score = 36.6 bits (83), Expect = 0.033
Identities = 20/56 (35%), Positives = 24/56 (42%), Gaps = 5/56 (8%)
Query: 7 RPPPLAPPAPPSPASPDPEPRTPGDAPGTPPRRPASPSALGELGLPVSPGSAQRTP 62
+PPP PP PP P P P P P PP P+ L + L V+ TP
Sbjct: 2404 QPPPPPPPPPPPPPPPPPPP-----PPPLPPPTSPKPTILPKKKLTVASPVTTATP 2454
Score = 36.2 bits (82), Expect = 0.043
Identities = 62/290 (21%), Positives = 109/290 (37%), Gaps = 34/290 (11%)
Query: 5 PRRPPPLAPPAPPSPASPDPEPRTPGDAPG----TPPRRPASPSALGELGLPVSPGSAQR 60
P++PPPL P SP + + P +A PP+ P+ PS + PV+ ++
Sbjct: 700 PKKPPPLVKQ-PTLHGSPSAKAKQPPEADSLSKPAPPKEPSVPSEQDKA--PVADDKPKQ 756
Query: 61 TPWSARETELLLGT--LLQPAVWRALLLDRRQ--ALPTYRRVSAALAQQ----QVRRTPA 112
T+L+ + +P + + + + + P + SA +Q + +P
Sbjct: 757 PKMVKPTTDLVSSSSATTKPDIPSSKVQSQAEEKTTPPLKTDSAKPSQSFPPTGEKVSPF 816
Query: 113 QCRRRYKFLKDKFREAHGQPPGPFDEQIRKLMGLLGDNGRKRPRRRSPGSGRPQRARRPV 172
+ + D +H PGP E K + +K +++ P+ +P+
Sbjct: 817 DSKAIPRPASDSKIISH---PGPSSES--KGQKQVDPVQKKEEPKKAQTKMSPKPDAKPM 871
Query: 173 PNAHAPAPSEPDATP---LPTARDRDADPTWTLRFSPSPPKSADASPAPGSPPAPAPTAL 229
P +P P P T +PT + + RFS + DA + + P T
Sbjct: 872 PKG-SPTPPGPRPTAGQTVPTPQQSPKPQEQSRRFSLNLGSITDAPKSQPTTPQETVTGK 930
Query: 230 -----ATCIPEDRAPVRGPGSPPPPPAREDPDSPPGRPEDCAPPPAAPPS 274
A+ + + G P P S PG P AP P+ PP+
Sbjct: 931 LFGFGASIFSQASNLISTAGQPGP-----HSQSGPGAPMKQAPAPSQPPT 975
Score = 35.4 bits (80), Expect = 0.074
Identities = 14/30 (46%), Positives = 16/30 (53%)
Query: 4 RPRRPPPLAPPAPPSPASPDPEPRTPGDAP 33
+P PPP PP PP P P P P P +P
Sbjct: 2404 QPPPPPPPPPPPPPPPPPPPPPPLPPPTSP 2433
Score = 35.4 bits (80), Expect = 0.074
Identities = 20/64 (31%), Positives = 26/64 (40%)
Query: 9 PPLAPPAPPSPASPDPEPRTPGDAPGTPPRRPASPSALGELGLPVSPGSAQRTPWSARET 68
PP PP PP P P P P P P T P+ P + PV+ + + ET
Sbjct: 2405 PPPPPPPPPPPPPPPPPPPPPPLPPPTSPKPTILPKKKLTVASPVTTATPLFDAVTTLET 2464
Query: 69 ELLL 72
+L
Sbjct: 2465 TAVL 2468
Score = 33.5 bits (75), Expect = 0.28
Identities = 63/297 (21%), Positives = 88/297 (29%), Gaps = 82/297 (27%)
Query: 5 PRRPPPLAP-PAPPSPASPDPE---PRTPGDAPGTPPRRPASPSALGELGLPVSPGSAQR 60
P +PP P PA P P P P P+ PG A P ++P S P PG A+
Sbjct: 466 PTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAK-PPSQQPGSTKPP-----PQQPGPAKP 519
Query: 61 TPWSARETELLLGTLLQPAVWRALLLDRRQALPTYRRVSAALAQQQVRRTPAQCRRRYKF 120
+P T+ P+ + SA + QQ
Sbjct: 520 SPQQPGSTKP----------------------PSQQPGSAKPSAQQP------------- 544
Query: 121 LKDKFREAHGQPPGPFDEQIRKLMGLLGDNGRKRPRRRSPGSGRPQ-----RARRPVPNA 175
P P +Q K + G +P SP + +P + P+ N
Sbjct: 545 ----------SPAKPSAQQSTKPVSQTGSGKPLQPPTVSPSAKQPPSQGLPKTICPLCNT 594
Query: 176 HAPAPSEPDATPLPTARDRDADPTWTLRFSPSPPKS-----------------ADASPAP 218
P+ T + F+P+P + D +P P
Sbjct: 595 TELLLHVPEKANFNTCTECQTTVCSLCGFNPNPHLTEVKEWLCLNCQMKRALGGDLAPVP 654
Query: 219 GSPPAPAPTALATCIPEDRAPVRGPGSPPPPPAREDPDSPPGRPEDCAPPPAAPPSL 275
SP TA P SP P D+ P + AP P PP L
Sbjct: 655 SSPQPKLKTA-----PVTTTSAVSKSSPQPQQTSPKKDAAPKQDLSKAPEPKKPPPL 706
Score = 33.5 bits (75), Expect = 0.28
Identities = 45/177 (25%), Positives = 60/177 (33%), Gaps = 51/177 (28%)
Query: 135 PFDEQIRKLMGLLGDN-GRKRPRRRSPGSGRPQRARRPVPNAHAPAPSEPDATPLPTARD 193
P EQ+ G+ G+++P + P SG P + + P++P ++ D
Sbjct: 2351 PMKEQLSTTYFTSGETFGQEKPASQLP-SGSP---------SVSSLPAKPRPFFRSSSLD 2400
Query: 194 RDADPTWTLRFSPSPPKSADASPAPGSPPAPAPTA----------------LATCIP--- 234
A P P PP P P PP P PT+ + T P
Sbjct: 2401 ISAQPPPP---PPPPPPPPPPPPPPPPPPLPPPTSPKPTILPKKKLTVASPVTTATPLFD 2457
Query: 235 -----EDRAPVRGPGSP-------PPPPAREDPDSPPG------RPEDCAPPPAAPP 273
E A +R G P PPP P S P RPE PP A P
Sbjct: 2458 AVTTLETTAVLRSNGLPVTRICTTAPPPVPPKPSSIPSGLVFTHRPEPSKPPIAPKP 2514
Score = 33.5 bits (75), Expect = 0.28
Identities = 25/89 (28%), Positives = 39/89 (43%), Gaps = 5/89 (5%)
Query: 174 NAHAPAPSEPDATPLPTARDRDADPTWTLRFSPSPPKSADASPAPGSPPAPAPTALATCI 233
+A +P + TPL T++ +PSPPKS +P SP +P + +
Sbjct: 3582 SATSPPKDKKRPTPLEIGYSSHLRADSTVQLAPSPPKSPKVLYSPISPLSPGKALESAFV 3641
Query: 234 PEDRAPVRGPGSPP----PPPAREDPDSP 258
P ++ P+ SP P A+ P SP
Sbjct: 3642 PYEK-PLPDDISPQKVLHPDMAKVPPASP 3669
Score = 33.1 bits (74), Expect = 0.37
Identities = 13/33 (39%), Positives = 16/33 (48%)
Query: 243 PGSPPPPPAREDPDSPPGRPEDCAPPPAAPPSL 275
P PPPPP P PP P PP + P++
Sbjct: 2405 PPPPPPPPPPPPPPPPPPPPPPLPPPTSPKPTI 2437
Score = 33.1 bits (74), Expect = 0.37
Identities = 14/35 (40%), Positives = 16/35 (45%)
Query: 5 PRRPPPLAPPAPPSPASPDPEPRTPGDAPGTPPRR 39
P PPP PP PP P P P P P P++
Sbjct: 2407 PPPPPPPPPPPPPPPPPPPPLPPPTSPKPTILPKK 2441
Score = 30.4 bits (67), Expect = 2.4
Identities = 22/71 (30%), Positives = 26/71 (36%), Gaps = 6/71 (8%)
Query: 204 FSPSPPKSADASPAPGSPPAPAPTALATCIPEDRAPVRGPGSPPPPPAREDPDSPPGRPE 263
F P S S +P PA P R+ + PPPP P PP P
Sbjct: 2367 FGQEKPASQLPSGSPSVSSLPAKPR-----PFFRSSSLDISAQPPPPPPPPPPPPPPPPP 2421
Query: 264 DCAPPPAAPPS 274
PPP PP+
Sbjct: 2422 P-PPPPLPPPT 2431
>gi|33356148 formin-like 1 [Homo sapiens]
Length = 1100
Score = 57.8 bits (138), Expect = 1e-08
Identities = 29/69 (42%), Positives = 36/69 (52%), Gaps = 1/69 (1%)
Query: 205 SPSPPKSADASPAPGSPPAPAPTALATCIPEDRAPVRGPGSPPPPPAREDPDSPPGRPED 264
SPSP + A PAPG+ P P P P++ P P +PP P + E P +PP P D
Sbjct: 525 SPSPDLAPAAEPAPGAAPPPPPPLPGLPSPQEAPPSAPPQAPPLPGSPEPPPAPP-LPGD 583
Query: 265 CAPPPAAPP 273
PPP PP
Sbjct: 584 LPPPPPPPP 592
Score = 53.1 bits (126), Expect = 3e-07
Identities = 43/118 (36%), Positives = 48/118 (40%), Gaps = 21/118 (17%)
Query: 165 PQRARRPVPNAHAPAPSE---PDATPLPTARDRDADPTWTLRFSPSPPKS-----ADASP 216
P P P +PS P A P P A P L PSP ++ A P
Sbjct: 511 PSGGDAPTPGVPTGSPSPDLAPAAEPAPGAAPPPPPPLPGL---PSPQEAPPSAPPQAPP 567
Query: 217 APGSP-PAPAPTALATCIPEDRAPVRGPGSPPPPPAREDPDSPPGRPEDCAPPPAAPP 273
PGSP P PAP +P D P P PPPPP + P PP P PPP PP
Sbjct: 568 LPGSPEPPPAPP-----LPGDLPP--PPPPPPPPPGTDGPVPPP--PPPPPPPPGGPP 616
Score = 47.4 bits (111), Expect = 2e-05
Identities = 25/54 (46%), Positives = 28/54 (51%), Gaps = 3/54 (5%)
Query: 5 PRRPPPLAPP-APPSPASPDPEPR--TPGDAPGTPPRRPASPSALGELGLPVSP 55
P+ PP APP APP P SP+P P PGD P PP P P G + P P
Sbjct: 554 PQEAPPSAPPQAPPLPGSPEPPPAPPLPGDLPPPPPPPPPPPGTDGPVPPPPPP 607
Score = 45.4 bits (106), Expect = 7e-05
Identities = 34/119 (28%), Positives = 44/119 (36%), Gaps = 17/119 (14%)
Query: 159 SPGSGRPQRARRPVPNAHAPAPSEPDATPLPTARDRDADPTWTLRFSPSPPKSADASPAP 218
+PG+ P P+P +P + P A P +P P+PP D P P
Sbjct: 537 APGAAPPPPP--PLPGLPSPQEAPPSAPPQAPPLPGSPEPP------PAPPLPGDLPPPP 588
Query: 219 GSPPAPAPTALATCIPEDRAPVRGPGSPPPPPAREDPDSPPGRPEDCAPPPAAPPSLNT 277
PP P P PV P PPPPP PD+ R + P A + T
Sbjct: 589 -PPPPPPPGT--------DGPVPPPPPPPPPPPGGPPDALGRRDSELGPGVKAKKPIQT 638
Score = 42.0 bits (97), Expect = 8e-04
Identities = 23/62 (37%), Positives = 25/62 (40%), Gaps = 4/62 (6%)
Query: 5 PRRPPPLAPPAPPSPASPDPEPRTPGDAPGTPPRRP----ASPSALGELGLPVSPGSAQR 60
P PPL PP P P P P T G P PP P P ALG + PG +
Sbjct: 574 PPPAPPLPGDLPPPPPPPPPPPGTDGPVPPPPPPPPPPPGGPPDALGRRDSELGPGVKAK 633
Query: 61 TP 62
P
Sbjct: 634 KP 635
Score = 39.7 bits (91), Expect = 0.004
Identities = 40/132 (30%), Positives = 45/132 (34%), Gaps = 26/132 (19%)
Query: 156 RRRSPGSGRPQRARRPVPNAHAP--APSEPDATPLPTAR------------DRDADPTWT 201
R R S +RRP AP AP+ P A L DA
Sbjct: 444 RERFSESTAMGASRRPPEPEKAPPAAPTRPSALELKVEELEEKGLIRILRGPGDAVSIEI 503
Query: 202 LRFSPSPPKSADASPAPGSPPAPAPTALATCIPEDRAPVRGPGSPPPPPAREDPDSPPGR 261
L + + P DA P PG P LA P G PPPPP PG
Sbjct: 504 LPVAVATPSGGDA-PTPGVPTGSPSPDLAPAAE----PAPGAAPPPPPPL-------PGL 551
Query: 262 PEDCAPPPAAPP 273
P PP+APP
Sbjct: 552 PSPQEAPPSAPP 563
Score = 35.0 bits (79), Expect = 0.097
Identities = 22/61 (36%), Positives = 26/61 (42%), Gaps = 7/61 (11%)
Query: 9 PPLAPPAPPSP-ASPDPEPRTPG------DAPGTPPRRPASPSALGELGLPVSPGSAQRT 61
P LAP A P+P A+P P P PG P PP+ P P + P PG
Sbjct: 528 PDLAPAAEPAPGAAPPPPPPLPGLPSPQEAPPSAPPQAPPLPGSPEPPPAPPLPGDLPPP 587
Query: 62 P 62
P
Sbjct: 588 P 588
Score = 35.0 bits (79), Expect = 0.097
Identities = 20/53 (37%), Positives = 23/53 (43%), Gaps = 5/53 (9%)
Query: 8 PPPLAPPAPPSPASPDPE---PRTPGDAPGTP--PRRPASPSALGELGLPVSP 55
P PP PP P P P+ P P AP P P P +P G+L P P
Sbjct: 538 PGAAPPPPPPLPGLPSPQEAPPSAPPQAPPLPGSPEPPPAPPLPGDLPPPPPP 590
Score = 32.0 bits (71), Expect = 0.82
Identities = 23/58 (39%), Positives = 26/58 (44%), Gaps = 4/58 (6%)
Query: 8 PPPLAPPAPPSP-ASPDPEPRTPGDAPGTPPRRPASPSALGELGLPVSPGSAQRTPWS 64
P P P PSP +P EP PG AP PP P PS + P +P A P S
Sbjct: 517 PTPGVPTGSPSPDLAPAAEP-APGAAPPPPPPLPGLPSP--QEAPPSAPPQAPPLPGS 571
>gi|24431933 reticulon 4 isoform B [Homo sapiens]
Length = 373
Score = 56.2 bits (134), Expect = 4e-08
Identities = 49/135 (36%), Positives = 58/135 (42%), Gaps = 30/135 (22%)
Query: 158 RSPGSGRPQRARRPVPNAHA--------------PAPSEPDATPLPTARDRDADPTWTLR 203
R P +G + PVP A A PAP P P A +R P+W
Sbjct: 57 RKPAAGL---SAAPVPTAPAAGAPLMDFGNDFVPPAPRGPLPAAPPVAPERQ--PSW--- 108
Query: 204 FSPSPPKSADASPAPGSPPAPAPTALATCIPEDRAPVRGPGSPPPPPAREDPDSPPGRPE 263
PSP S +P+P S A +P+ L PED P P PPPPPA P + P
Sbjct: 109 -DPSPVSSTVPAPSPLSAAAVSPSKL----PEDDEPPARP--PPPPPASVSPQAEPVWTP 161
Query: 264 DCAPPPAAPPSLNTA 278
AP PAAPPS A
Sbjct: 162 P-APAPAAPPSTPAA 175
Score = 42.7 bits (99), Expect = 5e-04
Identities = 20/45 (44%), Positives = 22/45 (48%), Gaps = 2/45 (4%)
Query: 8 PPPLAPPAPPSPASPDPEP--RTPGDAPGTPPRRPASPSALGELG 50
PP PP PP+ SP EP P AP PP PA+P G G
Sbjct: 139 PPARPPPPPPASVSPQAEPVWTPPAPAPAAPPSTPAAPKRRGSSG 183
Score = 37.7 bits (86), Expect = 0.015
Identities = 31/93 (33%), Positives = 35/93 (37%), Gaps = 5/93 (5%)
Query: 165 PQRARRPVPNAHAPAPS-EPDATPLPTARDRDA-DPTWTLRFSPSPPKSADASPAPGSPP 222
P R P+P A AP +P P P + A P SPS D PA PP
Sbjct: 87 PPAPRGPLPAAPPVAPERQPSWDPSPVSSTVPAPSPLSAAAVSPSKLPEDDEPPARPPPP 146
Query: 223 APA---PTALATCIPEDRAPVRGPGSPPPPPAR 252
PA P A P AP P +P P R
Sbjct: 147 PPASVSPQAEPVWTPPAPAPAAPPSTPAAPKRR 179
Score = 36.2 bits (82), Expect = 0.043
Identities = 21/51 (41%), Positives = 25/51 (49%), Gaps = 7/51 (13%)
Query: 5 PRRPPPLAPPAPPSPAS------PDPEPRTPGDAPGTPPRRPASPSALGEL 49
P RPPP PPA SP + P P P P P P RR +S S + +L
Sbjct: 140 PARPPP-PPPASVSPQAEPVWTPPAPAPAAPPSTPAAPKRRGSSGSVVVDL 189
Score = 31.2 bits (69), Expect = 1.4
Identities = 30/90 (33%), Positives = 33/90 (36%), Gaps = 29/90 (32%)
Query: 213 DASPAPGSPPAPAPTALATCIP-----EDRAP--VRG--PGSPPPPPARE---DPD---- 256
+ PA G AP PTA A P D P RG P +PP P R+ DP
Sbjct: 56 ERKPAAGLSAAPVPTAPAAGAPLMDFGNDFVPPAPRGPLPAAPPVAPERQPSWDPSPVSS 115
Query: 257 -------------SPPGRPEDCAPPPAAPP 273
SP PED PP PP
Sbjct: 116 TVPAPSPLSAAAVSPSKLPEDDEPPARPPP 145
>gi|47519490 reticulon 4 isoform D [Homo sapiens]
Length = 392
Score = 56.2 bits (134), Expect = 4e-08
Identities = 49/135 (36%), Positives = 58/135 (42%), Gaps = 30/135 (22%)
Query: 158 RSPGSGRPQRARRPVPNAHA--------------PAPSEPDATPLPTARDRDADPTWTLR 203
R P +G + PVP A A PAP P P A +R P+W
Sbjct: 57 RKPAAGL---SAAPVPTAPAAGAPLMDFGNDFVPPAPRGPLPAAPPVAPERQ--PSW--- 108
Query: 204 FSPSPPKSADASPAPGSPPAPAPTALATCIPEDRAPVRGPGSPPPPPAREDPDSPPGRPE 263
PSP S +P+P S A +P+ L PED P P PPPPPA P + P
Sbjct: 109 -DPSPVSSTVPAPSPLSAAAVSPSKL----PEDDEPPARP--PPPPPASVSPQAEPVWTP 161
Query: 264 DCAPPPAAPPSLNTA 278
AP PAAPPS A
Sbjct: 162 P-APAPAAPPSTPAA 175
Score = 42.7 bits (99), Expect = 5e-04
Identities = 20/45 (44%), Positives = 22/45 (48%), Gaps = 2/45 (4%)
Query: 8 PPPLAPPAPPSPASPDPEP--RTPGDAPGTPPRRPASPSALGELG 50
PP PP PP+ SP EP P AP PP PA+P G G
Sbjct: 139 PPARPPPPPPASVSPQAEPVWTPPAPAPAAPPSTPAAPKRRGSSG 183
Score = 38.1 bits (87), Expect = 0.011
Identities = 39/130 (30%), Positives = 49/130 (37%), Gaps = 7/130 (5%)
Query: 165 PQRARRPVPNAHAPAPS-EPDATPLPTARDRDA-DPTWTLRFSPSPPKSADASPAPGSPP 222
P R P+P A AP +P P P + A P SPS D PA PP
Sbjct: 87 PPAPRGPLPAAPPVAPERQPSWDPSPVSSTVPAPSPLSAAAVSPSKLPEDDEPPARPPPP 146
Query: 223 APA---PTALATCIPEDRAPVRGPGSPPPPPAREDPDSPPGRPEDCAPPPAAPPSLNTAL 279
PA P A P AP P +P P R S A P A+ P + ++
Sbjct: 147 PPASVSPQAEPVWTPPAPAPAAPPSTPAAPKRRGSSGSVD--ETLFALPAASEPVIRSSA 204
Query: 280 LQTLGHLGDI 289
+ L + DI
Sbjct: 205 VVDLLYWRDI 214
Score = 34.7 bits (78), Expect = 0.13
Identities = 20/46 (43%), Positives = 22/46 (47%), Gaps = 7/46 (15%)
Query: 5 PRRPPPLAPPAPPSPAS------PDPEPRTPGDAPGTPPRRPASPS 44
P RPPP PPA SP + P P P P P P RR +S S
Sbjct: 140 PARPPP-PPPASVSPQAEPVWTPPAPAPAAPPSTPAAPKRRGSSGS 184
Score = 31.2 bits (69), Expect = 1.4
Identities = 30/90 (33%), Positives = 33/90 (36%), Gaps = 29/90 (32%)
Query: 213 DASPAPGSPPAPAPTALATCIP-----EDRAP--VRG--PGSPPPPPARE---DPD---- 256
+ PA G AP PTA A P D P RG P +PP P R+ DP
Sbjct: 56 ERKPAAGLSAAPVPTAPAAGAPLMDFGNDFVPPAPRGPLPAAPPVAPERQPSWDPSPVSS 115
Query: 257 -------------SPPGRPEDCAPPPAAPP 273
SP PED PP PP
Sbjct: 116 TVPAPSPLSAAAVSPSKLPEDDEPPARPPP 145
>gi|24431935 reticulon 4 isoform A [Homo sapiens]
Length = 1192
Score = 56.2 bits (134), Expect = 4e-08
Identities = 49/135 (36%), Positives = 58/135 (42%), Gaps = 30/135 (22%)
Query: 158 RSPGSGRPQRARRPVPNAHA--------------PAPSEPDATPLPTARDRDADPTWTLR 203
R P +G + PVP A A PAP P P A +R P+W
Sbjct: 57 RKPAAGL---SAAPVPTAPAAGAPLMDFGNDFVPPAPRGPLPAAPPVAPERQ--PSW--- 108
Query: 204 FSPSPPKSADASPAPGSPPAPAPTALATCIPEDRAPVRGPGSPPPPPAREDPDSPPGRPE 263
PSP S +P+P S A +P+ L PED P P PPPPPA P + P
Sbjct: 109 -DPSPVSSTVPAPSPLSAAAVSPSKL----PEDDEPPARP--PPPPPASVSPQAEPVWTP 161
Query: 264 DCAPPPAAPPSLNTA 278
AP PAAPPS A
Sbjct: 162 P-APAPAAPPSTPAA 175
Score = 38.5 bits (88), Expect = 0.009
Identities = 22/50 (44%), Positives = 23/50 (46%), Gaps = 4/50 (8%)
Query: 5 PRRPPPLAPPAPPSPA--SPDPEP--RTPGDAPGTPPRRPASPSALGELG 50
P P A P PP PA SP EP P AP PP PA+P G G
Sbjct: 134 PEDDEPPARPPPPPPASVSPQAEPVWTPPAPAPAAPPSTPAAPKRRGSSG 183
Score = 37.7 bits (86), Expect = 0.015
Identities = 31/93 (33%), Positives = 35/93 (37%), Gaps = 5/93 (5%)
Query: 165 PQRARRPVPNAHAPAPS-EPDATPLPTARDRDA-DPTWTLRFSPSPPKSADASPAPGSPP 222
P R P+P A AP +P P P + A P SPS D PA PP
Sbjct: 87 PPAPRGPLPAAPPVAPERQPSWDPSPVSSTVPAPSPLSAAAVSPSKLPEDDEPPARPPPP 146
Query: 223 APA---PTALATCIPEDRAPVRGPGSPPPPPAR 252
PA P A P AP P +P P R
Sbjct: 147 PPASVSPQAEPVWTPPAPAPAAPPSTPAAPKRR 179
Score = 36.2 bits (82), Expect = 0.043
Identities = 32/106 (30%), Positives = 46/106 (43%), Gaps = 10/106 (9%)
Query: 5 PRRPPPLAPPAPPSPAS------PDPEPRTPGDAPGTPPRRPASPSALGEL-GLPVSPGS 57
P RPPP PPA SP + P P P P P P RR +S S L LP +
Sbjct: 140 PARPPP-PPPASVSPQAEPVWTPPAPAPAAPPSTPAAPKRRGSSGSVDETLFALPAASEP 198
Query: 58 AQRTPWSARETELLLGTLLQPAV--WRALLLDRRQALPTYRRVSAA 101
R+ + + G + + ++LL+ +LP+ +SAA
Sbjct: 199 VIRSSAENMDLKEQPGNTISAGQEDFPSVLLETAASLPSLSPLSAA 244
Score = 31.2 bits (69), Expect = 1.4
Identities = 30/90 (33%), Positives = 33/90 (36%), Gaps = 29/90 (32%)
Query: 213 DASPAPGSPPAPAPTALATCIP-----EDRAP--VRG--PGSPPPPPARE---DPD---- 256
+ PA G AP PTA A P D P RG P +PP P R+ DP
Sbjct: 56 ERKPAAGLSAAPVPTAPAAGAPLMDFGNDFVPPAPRGPLPAAPPVAPERQPSWDPSPVSS 115
Query: 257 -------------SPPGRPEDCAPPPAAPP 273
SP PED PP PP
Sbjct: 116 TVPAPSPLSAAAVSPSKLPEDDEPPARPPP 145
>gi|153792074 proline rich 12 [Homo sapiens]
Length = 2036
Score = 56.2 bits (134), Expect = 4e-08
Identities = 43/140 (30%), Positives = 51/140 (36%), Gaps = 12/140 (8%)
Query: 138 EQIRKLMGLLGDNGRKRPRRRSPGSGRPQRARRPVPNAHAPAPSEPDATPLPTARDRDAD 197
E I + L D P+ S G P P A P P P +
Sbjct: 1396 ESISSAISALDDPPLAGPKDTSTPDGPPL-----APAAAVPGPPPLPGLPSANSNGTPEP 1450
Query: 198 PTWTLRFSPSPPKSADASPAPGSPPAPAPTALAT----CIPEDRAPVRGPGSPPPPPARE 253
P + P+PP + P P PP P AL + P +P P PPPPPA
Sbjct: 1451 PLLEEKPPPTPPPAPTPQPQPPPPPPPPQPALPSPPPLVAPTPSSPPPPPLPPPPPPAM- 1509
Query: 254 DPDSPPGRPEDCAPPPAAPP 273
SPP P A P AAPP
Sbjct: 1510 --PSPPPPPPPAAAPLAAPP 1527
Score = 50.8 bits (120), Expect = 2e-06
Identities = 76/303 (25%), Positives = 108/303 (35%), Gaps = 52/303 (17%)
Query: 8 PPPLAPPAPPSPASPDPEPRTPGDAP-GTPPRRPASPSALG-EL--GLPVSPGSAQRTPW 63
PPPL PP PP+ SP P P P AP PP PA+PS EL P+ Q T
Sbjct: 1498 PPPLPPPPPPAMPSPPPPP-PPAAAPLAAPPEEPAAPSPEDPELPDTRPLHLAKKQETAA 1556
Query: 64 SARETELLLGTLLQPAVWRALLLDRRQALPTYRRVSAALAQQQVRRTPAQCRRRYKFLKD 123
ET+ G ++R +R + + + + Q R P R K L
Sbjct: 1557 VCGETDEEAGESGGEGIFR----ERDEFVIRAEDIPSLKLALQTGREPPPIWRVQKALLQ 1612
Query: 124 KFRE--AHGQPP-----------GPFDEQIRKLMGLLGDNGRK---------RPRRRSP- 160
KF GQ G + ++L +N K +P R P
Sbjct: 1613 KFTPEIKDGQRQFCATSNYLGYFGDAKNRYQRLYVKFLENVNKKDYVRVCARKPWHRPPV 1672
Query: 161 GSGRPQRARRPVP--NAHAPAPSEPDATPLPTARDRDADPTWTLRFSPSPPKSADASPAP 218
R +A+ PV + AP P P P P ++ S PP+ + P
Sbjct: 1673 PVRRSGQAKNPVSAGGSSAPPPKAPAPPPKPETPEKTT--------SEKPPEQTPETAMP 1724
Query: 219 GSPPAPAPTALATCIPEDR---------APVRGPGSPPPPPAREDPDSPPGRPEDCAPPP 269
PPAP +L + +++ P+RG + R + G+P P
Sbjct: 1725 -EPPAPEKPSLLRPVEKEKEKEKVTRGERPLRGERATSGRQTRPERSLATGQPATSRLPK 1783
Query: 270 AAP 272
A P
Sbjct: 1784 ARP 1786
Score = 47.8 bits (112), Expect = 1e-05
Identities = 35/114 (30%), Positives = 42/114 (36%), Gaps = 14/114 (12%)
Query: 155 PRRRSPGSGRPQRARRPVPNAHAPAPSEPDATPLPTARDRDADPTW------TLRFSPSP 208
P S G+ P P PAP+ P P + A P+ T P P
Sbjct: 1440 PSANSNGTPEPPLLEEKPPPTPPPAPTPQPQPPPPPPPPQPALPSPPPLVAPTPSSPPPP 1499
Query: 209 PKSADASPAPGSPPAPAPTALATCIPEDRAPVRGPGSPPPPPAREDPDSPPGRP 262
P PA SPP P P A A P+ P P P+ EDP+ P RP
Sbjct: 1500 PLPPPPPPAMPSPPPPPPPAAA--------PLAAPPEEPAAPSPEDPELPDTRP 1545
Score = 43.5 bits (101), Expect = 3e-04
Identities = 26/76 (34%), Positives = 37/76 (48%), Gaps = 7/76 (9%)
Query: 205 SPSPPKSADASPAPGSPPAPA-PTALATCIPE-----DRAPVRGPGSPPPPPAREDPDSP 258
+P P A A+ PG PP P P+A + PE ++ P P +P P P + P P
Sbjct: 1418 TPDGPPLAPAAAVPGPPPLPGLPSANSNGTPEPPLLEEKPPPTPPPAPTPQP-QPPPPPP 1476
Query: 259 PGRPEDCAPPPAAPPS 274
P +P +PPP P+
Sbjct: 1477 PPQPALPSPPPLVAPT 1492
Score = 40.8 bits (94), Expect = 0.002
Identities = 23/61 (37%), Positives = 27/61 (44%), Gaps = 1/61 (1%)
Query: 3 LRPRRPPPLAPPAP-PSPASPDPEPRTPGDAPGTPPRRPASPSALGELGLPVSPGSAQRT 61
L +PPP PPAP P P P P P P PP +PS+ LP P A +
Sbjct: 1452 LLEEKPPPTPPPAPTPQPQPPPPPPPPQPALPSPPPLVAPTPSSPPPPPLPPPPPPAMPS 1511
Query: 62 P 62
P
Sbjct: 1512 P 1512
Score = 38.1 bits (87), Expect = 0.011
Identities = 21/63 (33%), Positives = 25/63 (39%), Gaps = 1/63 (1%)
Query: 7 RPPPLAPPAPPSPASPDPEPRTPGDAPGTPPRRPASPSALGELGLPVSPGSAQRTPWSAR 66
+P P PP PP PA P P P P +PP P P + P P P +A
Sbjct: 1468 QPQPPPPPPPPQPALPSPPPLV-APTPSSPPPPPLPPPPPPAMPSPPPPPPPAAAPLAAP 1526
Query: 67 ETE 69
E
Sbjct: 1527 PEE 1529
Score = 36.6 bits (83), Expect = 0.033
Identities = 68/252 (26%), Positives = 83/252 (32%), Gaps = 59/252 (23%)
Query: 5 PRRPPPLAPPAPPSPASPDPEPRTPGDAPGTP-PR-RPAS----PSALGEL-----GLPV 53
P+ PPP PP PP P + R+ G P P PR RP P A+ EL LP
Sbjct: 833 PQPPPPPPPPPPPMPLQLEAHLRSHGLEPAAPSPRLRPEESLDPPGAMQELLGALEPLPP 892
Query: 54 SPG--------SAQRTPWSARETELLLGT-------LLQPAVWRALLLD-RRQALPTYRR 97
+PG S + P A + GT L +LL D R PT
Sbjct: 893 APGDTGVGPPNSEGKDPAGAYRSPSPQGTKAPRFVPLTSICFPDSLLQDEERSFFPTMEE 952
Query: 98 V-SAALAQQQVRRTPAQCRRRYKFLKDKFREAHGQPPGPFDEQIRKLMGLLGDNGRKRPR 156
+ A + P + K G PPGP G P
Sbjct: 953 MFGGGAADDYGKAGPPEDEGDPK-------AGAGPPPGP---------PAYDPYGPYCPG 996
Query: 157 RRSPGSGRPQRARRPVPNAHAPAPSEPDATPLPTARDRDADPTWTLRFSPSPPKSADASP 216
R S G+G PN PS +A PL + S P A P
Sbjct: 997 RAS-GAGPETPGLGLDPNKPPELPSTVNAEPLGLIQ--------------SGPHQAAPPP 1041
Query: 217 APGSPPAPAPTA 228
P PP PAP +
Sbjct: 1042 PPPPPPPPAPAS 1053
Score = 36.2 bits (82), Expect = 0.043
Identities = 31/121 (25%), Positives = 42/121 (34%), Gaps = 19/121 (15%)
Query: 178 PAPSEPDATPLPTARDRDAD-PTWTLRFSPSPPKSADASPAPGSPPAPAPTALATCIPED 236
P P+ P P +A P L P PP+ + + P+P+ + + + E
Sbjct: 767 PPPTAQSTQPTPHGLLLEAGGPDLPLVLPPPPPQLLPSVLSHAPSPSPSASKVGVHLLEP 826
Query: 237 RAPVRGPGSPPPPPAREDP------------------DSPPGRPEDCAPPPAAPPSLNTA 278
P PPPPP P SP RPE+ PP A L A
Sbjct: 827 ATRDGAPQPPPPPPPPPPPMPLQLEAHLRSHGLEPAAPSPRLRPEESLDPPGAMQELLGA 886
Query: 279 L 279
L
Sbjct: 887 L 887
Score = 34.3 bits (77), Expect = 0.16
Identities = 36/137 (26%), Positives = 54/137 (39%), Gaps = 21/137 (15%)
Query: 8 PPPLAPPAPPSPASPD------PEPRTPGDAPGTPPRRPASPSALGELGLPVSPGSAQRT 61
PPP AP PP P +P+ P +TP A PP P PS L + R
Sbjct: 1692 PPPKAPAPPPKPETPEKTTSEKPPEQTPETAMPEPPA-PEKPSLLRPVEKEKEKEKVTRG 1750
Query: 62 PWSARETELLLGTLLQPAVWRALLLDRRQALPTYRRVSAALAQQQVRRTPAQ--CRRRYK 119
R G +P ++L T + ++ L + + + A+ ++R K
Sbjct: 1751 ERPLRGERATSGRQTRP----------ERSLATGQPATSRLPKARPTKVKAEPPPKKRKK 1800
Query: 120 FLKDK--FREAHGQPPG 134
+LK+ A G PPG
Sbjct: 1801 WLKEAGGNATAGGGPPG 1817
Score = 33.5 bits (75), Expect = 0.28
Identities = 27/90 (30%), Positives = 32/90 (35%), Gaps = 16/90 (17%)
Query: 198 PTWTLRFSPSPPKSADASPAPGSPPAP----APTALATCIPEDRAP----VRGPGSPPPP 249
P T + P PP D P P P A ++ A E +P G PPP
Sbjct: 221 PAQTPPYRPGPP---DPPPPPRHLPTQFNLLASSSAAAAAAEQSSPQLYNFSGAAPGPPP 277
Query: 250 PAREDPDSPP-----GRPEDCAPPPAAPPS 274
P R P RP PPP PP+
Sbjct: 278 PERALPRQDTVIKHYQRPASAQPPPPPPPA 307
Score = 33.5 bits (75), Expect = 0.28
Identities = 24/86 (27%), Positives = 30/86 (34%), Gaps = 18/86 (20%)
Query: 204 FSPSPPKSADASPAPGSPPAPAPTALATCIPEDRAPVRGPGSPPPPPARE-DPDSPP--- 259
+ + P + P G+ P P P A P P R G+ P P DP+ PP
Sbjct: 962 YGKAGPPEDEGDPKAGAGPPPGPPAYDPYGP--YCPGRASGAGPETPGLGLDPNKPPELP 1019
Query: 260 ------------GRPEDCAPPPAAPP 273
P APPP PP
Sbjct: 1020 STVNAEPLGLIQSGPHQAAPPPPPPP 1045
Score = 33.1 bits (74), Expect = 0.37
Identities = 46/187 (24%), Positives = 58/187 (31%), Gaps = 47/187 (25%)
Query: 132 PPGPFDEQIRKLMGLLG-DNGRKRPRRRSPGSGRPQRARRPVPNAHAPAPSEPDATPLPT 190
PP P Q+ + G + PR R S P A + + A P P P T +
Sbjct: 842 PPPPMPLQLEAHLRSHGLEPAAPSPRLRPEESLDPPGAMQELLGALEPLPPAPGDTGVGP 901
Query: 191 ARDRDADPTWTLRFSPSPPKSADASPAPGSPPAPA---PTAL------------------ 229
DP R SPSP + AP P + P +L
Sbjct: 902 PNSEGKDPAGAYR-SPSP----QGTKAPRFVPLTSICFPDSLLQDEERSFFPTMEEMFGG 956
Query: 230 -------ATCIPEDRAPVRGPGSPPPPPAREDPDSP--PGRPEDCAP-----------PP 269
PED + PPP P DP P PGR P PP
Sbjct: 957 GAADDYGKAGPPEDEGDPKAGAGPPPGPPAYDPYGPYCPGRASGAGPETPGLGLDPNKPP 1016
Query: 270 AAPPSLN 276
P ++N
Sbjct: 1017 ELPSTVN 1023
Score = 32.0 bits (71), Expect = 0.82
Identities = 16/36 (44%), Positives = 18/36 (50%), Gaps = 1/36 (2%)
Query: 9 PPLAPPAPPSPASPDPEPRTPGDAPGTPPRRPASPS 44
PPL PP P P P+ P P PP +PA PS
Sbjct: 1450 PPLLEEKPPPTPPPAPTPQ-PQPPPPPPPPQPALPS 1484
Score = 31.6 bits (70), Expect = 1.1
Identities = 49/220 (22%), Positives = 77/220 (35%), Gaps = 59/220 (26%)
Query: 7 RPPPLAPPAPPSPASPDPEPRTPGDAPGTPPRRPASPSALGELGLPVSPG--SAQRTPWS 64
R P PP P + P + G + PP+ PA P P +P ++++ P
Sbjct: 1664 RKPWHRPPVPVRRSGQAKNPVSAGGSSAPPPKAPAPPPK------PETPEKTTSEKPPEQ 1717
Query: 65 ARETELLLGTLLQPAVWRALLLDRRQALPTYRRVSAALAQQQVRRTPAQCRRRYKFLKDK 124
ET A+ + P+ R K K+K
Sbjct: 1718 TPET--------------------------------AMPEPPAPEKPSLLRPVEKE-KEK 1744
Query: 125 FREAHGQPPGPFDEQIRKLMGLLGDNGRKRPRRRSPGSGRPQRARRPVPNAHAPAPSEPD 184
+ G+ P L G +GR+ RS +G+P +R P P++
Sbjct: 1745 EKVTRGERP---------LRGERATSGRQTRPERSLATGQPATSRLP-----KARPTKVK 1790
Query: 185 ATPLPTARD---RDADPTWTLRFSPSPPKSADASPAPGSP 221
A P P R ++A T P P S+D+ +PG+P
Sbjct: 1791 AEPPPKKRKKWLKEAGGNATAGGGP-PGSSSDSESSPGAP 1829
Score = 30.8 bits (68), Expect = 1.8
Identities = 21/54 (38%), Positives = 24/54 (44%), Gaps = 3/54 (5%)
Query: 9 PPLAPPAPPSPASPDPEPRTPGDAPGTPPRRPASPSALGELGLPVSPGSAQRTP 62
PPLA P S +PD P P A PP P PSA G P P ++ P
Sbjct: 1408 PPLAGPKDTS--TPDGPPLAPAAAVPGPPPLPGLPSA-NSNGTPEPPLLEEKPP 1458
Score = 30.8 bits (68), Expect = 1.8
Identities = 26/86 (30%), Positives = 31/86 (36%), Gaps = 12/86 (13%)
Query: 165 PQRARRPVPNAHAPAPSEPDATPLPTARDRDADPTWTLRFSPSPPKSAD--------ASP 216
PQ A P AP PS P PLP P P PP +A A+P
Sbjct: 1478 PQPALPSPPPLVAPTPSSPPPPPLPPP----PPPAMPSPPPPPPPAAAPLAAPPEEPAAP 1533
Query: 217 APGSPPAPAPTALATCIPEDRAPVRG 242
+P P P L ++ A V G
Sbjct: 1534 SPEDPELPDTRPLHLAKKQETAAVCG 1559
Score = 30.0 bits (66), Expect = 3.1
Identities = 25/82 (30%), Positives = 31/82 (37%), Gaps = 7/82 (8%)
Query: 176 HAPAPSEPDATP--LPTA----RDRDADPTWTLRFSPSPPKSADASPAPGSPPAPAPTAL 229
+ P P +P P LPT A + SP + A+P P PP A
Sbjct: 227 YRPGPPDPPPPPRHLPTQFNLLASSSAAAAAAEQSSPQLYNFSGAAPGP-PPPERALPRQ 285
Query: 230 ATCIPEDRAPVRGPGSPPPPPA 251
T I + P PPPPPA
Sbjct: 286 DTVIKHYQRPASAQPPPPPPPA 307
Score = 28.5 bits (62), Expect = 9.1
Identities = 25/77 (32%), Positives = 28/77 (36%), Gaps = 19/77 (24%)
Query: 5 PRRPPPLAPPAPP-------------SPASPDPEPRTP------GDAPGTPPRRPASPSA 45
P RP P PP PP S A+ E +P G APG PP A P
Sbjct: 226 PYRPGPPDPPPPPRHLPTQFNLLASSSAAAAAAEQSSPQLYNFSGAAPGPPPPERALPRQ 285
Query: 46 LGELGLPVSPGSAQRTP 62
+ P SAQ P
Sbjct: 286 DTVIKHYQRPASAQPPP 302
Score = 28.5 bits (62), Expect = 9.1
Identities = 27/109 (24%), Positives = 40/109 (36%), Gaps = 6/109 (5%)
Query: 180 PSEPDATPLPTARDRDADPTWTLRFSPSPPKSADASPAP---GSPPAPAPTALATCIPED 236
P E + P A P + P +++ A P G P P +T E
Sbjct: 967 PPEDEGDPKAGAGPPPGPPAYDPYGPYCPGRASGAGPETPGLGLDPNKPPELPSTVNAEP 1026
Query: 237 RAPVR-GP--GSPPPPPAREDPDSPPGRPEDCAPPPAAPPSLNTALLQT 282
++ GP +PPPPP P +P P+ P + LL+T
Sbjct: 1027 LGLIQSGPHQAAPPPPPPPPPPPAPASEPKGGLTSPIFCSTKPKKLLKT 1075
Score = 28.5 bits (62), Expect = 9.1
Identities = 23/65 (35%), Positives = 28/65 (43%), Gaps = 10/65 (15%)
Query: 8 PPPLAPPAPPSPASPDPE--------PRTPGDAPGTPPRRPASPSALGELGLPVSPGSAQ 59
PPPL P P + ++ PE P TP AP TP +P P + LP P
Sbjct: 1433 PPPL-PGLPSANSNGTPEPPLLEEKPPPTPPPAP-TPQPQPPPPPPPPQPALPSPPPLVA 1490
Query: 60 RTPWS 64
TP S
Sbjct: 1491 PTPSS 1495
>gi|33286446 opioid growth factor receptor [Homo sapiens]
Length = 677
Score = 55.1 bits (131), Expect = 9e-08
Identities = 77/310 (24%), Positives = 106/310 (34%), Gaps = 70/310 (22%)
Query: 18 SPASPDPEPRTPGDAPGT------------PPRRPASPSALGELGLPVSP-----GSAQR 60
SP PD E T G G P R P G L G +
Sbjct: 315 SPGDPDHEASTQGRTCGPEHSKGGGRVDEGPQPRSVEPQDAGPLERSQGDEAGGHGEDRP 374
Query: 61 TPWSARETELLLGTLLQPAVWRALLLDRRQALPTYRRVSAALAQQQVRRTPAQCRRRYKF 120
P S +E++ R L L RR+ PT +A +++ C
Sbjct: 375 EPLSPKESKK-----------RKLELSRREQPPTEPGPQSASEVEKIALNLEGCALSQGS 423
Query: 121 LKDKFREAHGQPPGPFDEQIRKLMGL-LGDNGRKRPRRRSPGSGRPQR-----------A 168
L+ +E GQ PG + R+ +G + D RKR R+ G+G A
Sbjct: 424 LRTGTQEVGGQDPGEAVQPCRQPLGARVADKVRKR-RKVDEGAGDSAAVASGGAQTLALA 482
Query: 169 RRPVPNAHAPA---------------------PSEPDATPLPT----ARDRDAD-PTWTL 202
P P+ H A P P TP P+ A D A+ P+ T
Sbjct: 483 GSPAPSGHPKAGHSENGVEEDTEGRTGPKEGTPGSPSETPGPSPAGPAGDEPAESPSETP 542
Query: 203 RFSPSPPKSADASPAPGSPPAPAPTALATCIPEDRAPVRGPGSPPPPPAREDPDSPPGRP 262
P+ P + + +P P P P A P + +P PG P P R++P P
Sbjct: 543 GPRPAGPAGDEPAESPSETPGPRPAGPAGDEPAE-SPSETPGPSPAGPTRDEPAESPS-- 599
Query: 263 EDCAPPPAAP 272
E P PA P
Sbjct: 600 ETPGPRPAGP 609
Score = 48.1 bits (113), Expect = 1e-05
Identities = 44/145 (30%), Positives = 59/145 (40%), Gaps = 10/145 (6%)
Query: 130 GQPPGPFDEQIRKLMGLLGDNGRKRPRRRSPGSGRPQRARRPVPNAHAPAPSE-PDATPL 188
G P P + G GD + P +PG R P + A +PSE P P
Sbjct: 513 GTPGSPSETPGPSPAGPAGDEPAESPSE-TPGP----RPAGPAGDEPAESPSETPGPRPA 567
Query: 189 PTARDRDAD-PTWTLRFSPSPPKSADASPAPGSPPAPAPTALATCIPEDRAPVRGPGSPP 247
A D A+ P+ T SP+ P + + +P P P P A P + +P PG P
Sbjct: 568 GPAGDEPAESPSETPGPSPAGPTRDEPAESPSETPGPRPAGPAGDEPAE-SPSETPGPRP 626
Query: 248 PPPAREDPDSPPGRPEDCAPPPAAP 272
PA ++P P E P PA P
Sbjct: 627 AGPAGDEPAESPS--ETPGPSPAGP 649
Score = 45.8 bits (107), Expect = 5e-05
Identities = 39/133 (29%), Positives = 50/133 (37%), Gaps = 20/133 (15%)
Query: 151 GRKRPRRRSPGSGRPQRARRPVPNAHAPAPSEPDATPLPTARDRDA---------DPTWT 201
GR P+ +PGS + P P+ PA EP +P T R A P+ T
Sbjct: 506 GRTGPKEGTPGSP----SETPGPSPAGPAGDEPAESPSETPGPRPAGPAGDEPAESPSET 561
Query: 202 LRFSPSPPKSADASPAPGSPPAPAPTALATCIPEDRAPVRGPGSPPPP-PAREDPDSPPG 260
P+ P + + +P P P+P P P P P P PA D P
Sbjct: 562 PGPRPAGPAGDEPAESPSETPGPSPAG-----PTRDEPAESPSETPGPRPAGPAGDEPAE 616
Query: 261 RP-EDCAPPPAAP 272
P E P PA P
Sbjct: 617 SPSETPGPRPAGP 629
Score = 45.1 bits (105), Expect = 9e-05
Identities = 39/135 (28%), Positives = 58/135 (42%), Gaps = 14/135 (10%)
Query: 123 DKFREAHGQPPGPFDEQIRKLMGLLGDNGRKRPRRRSPGSGRPQRARRPVPNAHAPAPSE 182
D+ E+ + PGP + G GD + P +PG R P + A +PSE
Sbjct: 532 DEPAESPSETPGP------RPAGPAGDEPAESPSE-TPGP----RPAGPAGDEPAESPSE 580
Query: 183 -PDATPLPTARDRDAD-PTWTLRFSPSPPKSADASPAPGSPPAPAPTALATCIPEDRAPV 240
P +P RD A+ P+ T P+ P + + +P P P P A P + +P
Sbjct: 581 TPGPSPAGPTRDEPAESPSETPGPRPAGPAGDEPAESPSETPGPRPAGPAGDEPAE-SPS 639
Query: 241 RGPGSPPPPPAREDP 255
PG P P R++P
Sbjct: 640 ETPGPSPAGPTRDEP 654
>gi|51702526 Wiskott-Aldrich syndrome gene-like protein [Homo
sapiens]
Length = 505
Score = 55.1 bits (131), Expect = 9e-08
Identities = 47/158 (29%), Positives = 57/158 (36%), Gaps = 30/158 (18%)
Query: 156 RRRSPGSGRPQRARRPVPNAHAPAPSEPDATPLPTARDRDADPTWTLRFSPSPPKSADAS 215
RR++P P R P P P P P P AR R A P PP S +
Sbjct: 273 RRQAPPPPPPSRGGPPPP----PPPPHNSGPPPPPARGRGAPP---------PPPSRAPT 319
Query: 216 PAPGSPPAPAPTALATCIPEDR--------APVRGPGSPPPPPAR-------EDPDSPPG 260
AP PP P+ P +R P P PPPPP P PP
Sbjct: 320 AAPPPPPPSRPSVAVPPPPPNRMYPPPPPALPSSAPSGPPPPPPSVLGVGPVAPPPPPPP 379
Query: 261 RPEDCAPPPAAPPSLNTALLQTLGHLGDIANILGPLRD 298
P PPP PS + T G+ A +L +R+
Sbjct: 380 PPPPGPPPPPGLPSDGDHQVPTTA--GNKAALLDQIRE 415
Score = 53.5 bits (127), Expect = 3e-07
Identities = 43/138 (31%), Positives = 54/138 (39%), Gaps = 29/138 (21%)
Query: 149 DNGRKRPRRRSPGSGRPQRARRPVPNAHAPAPSEPD-ATPLPTARDRDADPTWTLRFSPS 207
++G P R G+ P +R P P PS P A P P R P
Sbjct: 296 NSGPPPPPARGRGAPPPPPSRAPTAAPPPPPPSRPSVAVPPPPPN----------RMYPP 345
Query: 208 PPKSADASPAPGSPPAPAPTALATCIPEDRAPVRGPGSPPPPPAREDPDSPPGRPEDCAP 267
PP + +S G PP P P+ L GP +PPPPP P PPG P P
Sbjct: 346 PPPALPSSAPSG-PPPPPPSVLGV----------GPVAPPPPP---PPPPPPGPP----P 387
Query: 268 PPAAPPSLNTALLQTLGH 285
PP P + + T G+
Sbjct: 388 PPGLPSDGDHQVPTTAGN 405
Score = 43.5 bits (101), Expect = 3e-04
Identities = 20/51 (39%), Positives = 23/51 (45%)
Query: 5 PRRPPPLAPPAPPSPASPDPEPRTPGDAPGTPPRRPASPSALGELGLPVSP 55
P RP PP PP+ P P P P AP PP P S +G + P P
Sbjct: 327 PSRPSVAVPPPPPNRMYPPPPPALPSSAPSGPPPPPPSVLGVGPVAPPPPP 377
Score = 37.4 bits (85), Expect = 0.019
Identities = 16/35 (45%), Positives = 20/35 (57%), Gaps = 2/35 (5%)
Query: 240 VRGPGSPPPPPAREDPDSPPGRPEDCAPPPAAPPS 274
+R PPPPP+R P PP P + PPP PP+
Sbjct: 272 LRRQAPPPPPPSRGGPPPPPPPPHNSGPPP--PPA 304
Score = 35.0 bits (79), Expect = 0.097
Identities = 20/64 (31%), Positives = 25/64 (39%), Gaps = 6/64 (9%)
Query: 5 PRRPPPLAPPAPPSPASPDPEPRTPGDAPGTPPRR------PASPSALGELGLPVSPGSA 58
P R P PP PP + P P P AP PP R P P + + +P P +
Sbjct: 282 PSRGGPPPPPPPPHNSGPPPPPARGRGAPPPPPSRAPTAAPPPPPPSRPSVAVPPPPPNR 341
Query: 59 QRTP 62
P
Sbjct: 342 MYPP 345
Score = 35.0 bits (79), Expect = 0.097
Identities = 17/42 (40%), Positives = 19/42 (45%), Gaps = 2/42 (4%)
Query: 5 PRRPPPLAPPAPPSPASPDPEPRTPGDAPGTPPRRPASPSAL 46
P PPP PP PP P P P P P D P + +AL
Sbjct: 370 PVAPPP--PPPPPPPPGPPPPPGLPSDGDHQVPTTAGNKAAL 409
Score = 32.7 bits (73), Expect = 0.48
Identities = 25/76 (32%), Positives = 29/76 (38%), Gaps = 7/76 (9%)
Query: 4 RPRRPPPLAPPAPPSPASPDPEPRTPGDA-PGTPPRRPASPSALGELGLPVSPGSAQRTP 62
R R PP P P+ A P P P P A P PP R P P P SA P
Sbjct: 305 RGRGAPPPPPSRAPTAAPPPPPPSRPSVAVPPPPPNRMYPPPP------PALPSSAPSGP 358
Query: 63 WSARETELLLGTLLQP 78
+ L +G + P
Sbjct: 359 PPPPPSVLGVGPVAPP 374
Score = 32.7 bits (73), Expect = 0.48
Identities = 26/79 (32%), Positives = 30/79 (37%), Gaps = 4/79 (5%)
Query: 5 PRRPPPLAPPAPPSPASPDPEPRTP---GDAPGTPPRRPASPSALGELGLPVSPGSA-QR 60
P R P PPA PS A P P P G P PP P P G P P +
Sbjct: 339 PNRMYPPPPPALPSSAPSGPPPPPPSVLGVGPVAPPPPPPPPPPPGPPPPPGLPSDGDHQ 398
Query: 61 TPWSARETELLLGTLLQPA 79
P +A LL + + A
Sbjct: 399 VPTTAGNKAALLDQIREGA 417
Score = 32.0 bits (71), Expect = 0.82
Identities = 21/64 (32%), Positives = 26/64 (40%), Gaps = 7/64 (10%)
Query: 6 RRPPPLAPPAPPSPASPDPEPRTPGDAP------GTPPRRPA-SPSALGELGLPVSPGSA 58
R+ PP PP+ P P P P G P G PP P+ +P+A P P A
Sbjct: 274 RQAPPPPPPSRGGPPPPPPPPHNSGPPPPPARGRGAPPPPPSRAPTAAPPPPPPSRPSVA 333
Query: 59 QRTP 62
P
Sbjct: 334 VPPP 337
>gi|20986497 mitogen-activated protein kinase 7 isoform 1 [Homo
sapiens]
Length = 816
Score = 55.1 bits (131), Expect = 9e-08
Identities = 77/276 (27%), Positives = 96/276 (34%), Gaps = 49/276 (17%)
Query: 8 PPPLAPPAPPSPASPDPEPRT-PGDAPGTPPRRPASPSALGELGLPVSPGSAQRTPWSAR 66
P P AP + SP P P PG AP T P + E P G+ +A
Sbjct: 420 PSPWAPSGDCAMESPPPAPPPCPGPAPDTIDLTLQPPPPVSEPAPPKKDGAISDNTKAAL 479
Query: 67 ETELLLGTLLQPAVWRALLLDRRQA-LPTYRRVSAALAQQQVRRTPAQCRRRYKFLKDKF 125
+ LL R+ L D A L AQ++ R + RRR + K++
Sbjct: 480 KAALLKSL-------RSRLRDGPSAPLEAPEPRKPVTAQERQREREEKRRRRQERAKERE 532
Query: 126 REAH---------GQPPGPFDEQIRKLMGLLGDNGRKRPRRRSPGSGRPQRARRPVPNAH 176
+ G GP + + L+ L DN R R + R RP
Sbjct: 533 KRRQERERKERGAGASGGPSTDPLAGLV--LSDNDRSLLERWT-------RMARPA---- 579
Query: 177 APA-PSEPDATPLPTARDRDADPTWTLRFSPSPPKSADASPAPGSPPAPAPTALATCIPE 235
APA S P P PT PT SPP A P P + T+
Sbjct: 580 APALTSVPAPAPAPTPTPTPVQPT-------SPPPGPVAQPTGPQPQSAGSTS------- 625
Query: 236 DRAPVRGPGSPPPPPAREDPDSPPGRPEDCAPPPAA 271
PV P PPP PA P PPG APP A
Sbjct: 626 --GPVPQPACPPPGPA-PHPTGPPGPIPVPAPPQIA 658
Score = 30.8 bits (68), Expect = 1.8
Identities = 14/42 (33%), Positives = 18/42 (42%)
Query: 2 LLRPRRPPPLAPPAPPSPASPDPEPRTPGDAPGTPPRRPASP 43
+ RP P + PAP +P P P P P P +P P
Sbjct: 575 MARPAAPALTSVPAPAPAPTPTPTPVQPTSPPPGPVAQPTGP 616
Score = 28.9 bits (63), Expect = 6.9
Identities = 26/86 (30%), Positives = 29/86 (33%), Gaps = 20/86 (23%)
Query: 8 PPPLAPPAPPSPASPDP---------EPRTPGDA------PGTPPRRPASPSALGELGLP 52
P P P P P SP P +P++ G P PP PA P G P
Sbjct: 591 PAPTPTPTPVQPTSPPPGPVAQPTGPQPQSAGSTSGPVPQPACPPPGPA-PHPTG----P 645
Query: 53 VSPGSAQRTPWSARETELLLGTLLQP 78
P P A T LL L P
Sbjct: 646 PGPIPVPAPPQIATSTSLLAAQSLVP 671
Score = 28.9 bits (63), Expect = 6.9
Identities = 18/53 (33%), Positives = 20/53 (37%), Gaps = 8/53 (15%)
Query: 4 RPRRPPPLAPPAPPSPASPDPEPRTPGDAPGTPPRRPASPSALGELGLPVSPG 56
+P PPP P P P P P P PP+ S S L L PG
Sbjct: 630 QPACPPPGPAPHPTGPPGPIPVP--------APPQIATSTSLLAAQSLVPPPG 674
>gi|209529736 mitogen-activated protein kinase 7 isoform 1 [Homo
sapiens]
Length = 816
Score = 55.1 bits (131), Expect = 9e-08
Identities = 77/276 (27%), Positives = 96/276 (34%), Gaps = 49/276 (17%)
Query: 8 PPPLAPPAPPSPASPDPEPRT-PGDAPGTPPRRPASPSALGELGLPVSPGSAQRTPWSAR 66
P P AP + SP P P PG AP T P + E P G+ +A
Sbjct: 420 PSPWAPSGDCAMESPPPAPPPCPGPAPDTIDLTLQPPPPVSEPAPPKKDGAISDNTKAAL 479
Query: 67 ETELLLGTLLQPAVWRALLLDRRQA-LPTYRRVSAALAQQQVRRTPAQCRRRYKFLKDKF 125
+ LL R+ L D A L AQ++ R + RRR + K++
Sbjct: 480 KAALLKSL-------RSRLRDGPSAPLEAPEPRKPVTAQERQREREEKRRRRQERAKERE 532
Query: 126 REAH---------GQPPGPFDEQIRKLMGLLGDNGRKRPRRRSPGSGRPQRARRPVPNAH 176
+ G GP + + L+ L DN R R + R RP
Sbjct: 533 KRRQERERKERGAGASGGPSTDPLAGLV--LSDNDRSLLERWT-------RMARPA---- 579
Query: 177 APA-PSEPDATPLPTARDRDADPTWTLRFSPSPPKSADASPAPGSPPAPAPTALATCIPE 235
APA S P P PT PT SPP A P P + T+
Sbjct: 580 APALTSVPAPAPAPTPTPTPVQPT-------SPPPGPVAQPTGPQPQSAGSTS------- 625
Query: 236 DRAPVRGPGSPPPPPAREDPDSPPGRPEDCAPPPAA 271
PV P PPP PA P PPG APP A
Sbjct: 626 --GPVPQPACPPPGPA-PHPTGPPGPIPVPAPPQIA 658
Score = 30.8 bits (68), Expect = 1.8
Identities = 14/42 (33%), Positives = 18/42 (42%)
Query: 2 LLRPRRPPPLAPPAPPSPASPDPEPRTPGDAPGTPPRRPASP 43
+ RP P + PAP +P P P P P P +P P
Sbjct: 575 MARPAAPALTSVPAPAPAPTPTPTPVQPTSPPPGPVAQPTGP 616
Score = 28.9 bits (63), Expect = 6.9
Identities = 26/86 (30%), Positives = 29/86 (33%), Gaps = 20/86 (23%)
Query: 8 PPPLAPPAPPSPASPDP---------EPRTPGDA------PGTPPRRPASPSALGELGLP 52
P P P P P SP P +P++ G P PP PA P G P
Sbjct: 591 PAPTPTPTPVQPTSPPPGPVAQPTGPQPQSAGSTSGPVPQPACPPPGPA-PHPTG----P 645
Query: 53 VSPGSAQRTPWSARETELLLGTLLQP 78
P P A T LL L P
Sbjct: 646 PGPIPVPAPPQIATSTSLLAAQSLVP 671
Score = 28.9 bits (63), Expect = 6.9
Identities = 18/53 (33%), Positives = 20/53 (37%), Gaps = 8/53 (15%)
Query: 4 RPRRPPPLAPPAPPSPASPDPEPRTPGDAPGTPPRRPASPSALGELGLPVSPG 56
+P PPP P P P P P P PP+ S S L L PG
Sbjct: 630 QPACPPPGPAPHPTGPPGPIPVP--------APPQIATSTSLLAAQSLVPPPG 674
>gi|209529734 mitogen-activated protein kinase 7 isoform 1 [Homo
sapiens]
Length = 816
Score = 55.1 bits (131), Expect = 9e-08
Identities = 77/276 (27%), Positives = 96/276 (34%), Gaps = 49/276 (17%)
Query: 8 PPPLAPPAPPSPASPDPEPRT-PGDAPGTPPRRPASPSALGELGLPVSPGSAQRTPWSAR 66
P P AP + SP P P PG AP T P + E P G+ +A
Sbjct: 420 PSPWAPSGDCAMESPPPAPPPCPGPAPDTIDLTLQPPPPVSEPAPPKKDGAISDNTKAAL 479
Query: 67 ETELLLGTLLQPAVWRALLLDRRQA-LPTYRRVSAALAQQQVRRTPAQCRRRYKFLKDKF 125
+ LL R+ L D A L AQ++ R + RRR + K++
Sbjct: 480 KAALLKSL-------RSRLRDGPSAPLEAPEPRKPVTAQERQREREEKRRRRQERAKERE 532
Query: 126 REAH---------GQPPGPFDEQIRKLMGLLGDNGRKRPRRRSPGSGRPQRARRPVPNAH 176
+ G GP + + L+ L DN R R + R RP
Sbjct: 533 KRRQERERKERGAGASGGPSTDPLAGLV--LSDNDRSLLERWT-------RMARPA---- 579
Query: 177 APA-PSEPDATPLPTARDRDADPTWTLRFSPSPPKSADASPAPGSPPAPAPTALATCIPE 235
APA S P P PT PT SPP A P P + T+
Sbjct: 580 APALTSVPAPAPAPTPTPTPVQPT-------SPPPGPVAQPTGPQPQSAGSTS------- 625
Query: 236 DRAPVRGPGSPPPPPAREDPDSPPGRPEDCAPPPAA 271
PV P PPP PA P PPG APP A
Sbjct: 626 --GPVPQPACPPPGPA-PHPTGPPGPIPVPAPPQIA 658
Score = 30.8 bits (68), Expect = 1.8
Identities = 14/42 (33%), Positives = 18/42 (42%)
Query: 2 LLRPRRPPPLAPPAPPSPASPDPEPRTPGDAPGTPPRRPASP 43
+ RP P + PAP +P P P P P P +P P
Sbjct: 575 MARPAAPALTSVPAPAPAPTPTPTPVQPTSPPPGPVAQPTGP 616
Score = 28.9 bits (63), Expect = 6.9
Identities = 26/86 (30%), Positives = 29/86 (33%), Gaps = 20/86 (23%)
Query: 8 PPPLAPPAPPSPASPDP---------EPRTPGDA------PGTPPRRPASPSALGELGLP 52
P P P P P SP P +P++ G P PP PA P G P
Sbjct: 591 PAPTPTPTPVQPTSPPPGPVAQPTGPQPQSAGSTSGPVPQPACPPPGPA-PHPTG----P 645
Query: 53 VSPGSAQRTPWSARETELLLGTLLQP 78
P P A T LL L P
Sbjct: 646 PGPIPVPAPPQIATSTSLLAAQSLVP 671
Score = 28.9 bits (63), Expect = 6.9
Identities = 18/53 (33%), Positives = 20/53 (37%), Gaps = 8/53 (15%)
Query: 4 RPRRPPPLAPPAPPSPASPDPEPRTPGDAPGTPPRRPASPSALGELGLPVSPG 56
+P PPP P P P P P P PP+ S S L L PG
Sbjct: 630 QPACPPPGPAPHPTGPPGPIPVP--------APPQIATSTSLLAAQSLVPPPG 674
>gi|20986499 mitogen-activated protein kinase 7 isoform 2 [Homo
sapiens]
Length = 677
Score = 55.1 bits (131), Expect = 9e-08
Identities = 77/276 (27%), Positives = 96/276 (34%), Gaps = 49/276 (17%)
Query: 8 PPPLAPPAPPSPASPDPEPRT-PGDAPGTPPRRPASPSALGELGLPVSPGSAQRTPWSAR 66
P P AP + SP P P PG AP T P + E P G+ +A
Sbjct: 281 PSPWAPSGDCAMESPPPAPPPCPGPAPDTIDLTLQPPPPVSEPAPPKKDGAISDNTKAAL 340
Query: 67 ETELLLGTLLQPAVWRALLLDRRQA-LPTYRRVSAALAQQQVRRTPAQCRRRYKFLKDKF 125
+ LL R+ L D A L AQ++ R + RRR + K++
Sbjct: 341 KAALLKSL-------RSRLRDGPSAPLEAPEPRKPVTAQERQREREEKRRRRQERAKERE 393
Query: 126 REAH---------GQPPGPFDEQIRKLMGLLGDNGRKRPRRRSPGSGRPQRARRPVPNAH 176
+ G GP + + L+ L DN R R + R RP
Sbjct: 394 KRRQERERKERGAGASGGPSTDPLAGLV--LSDNDRSLLERWT-------RMARPA---- 440
Query: 177 APA-PSEPDATPLPTARDRDADPTWTLRFSPSPPKSADASPAPGSPPAPAPTALATCIPE 235
APA S P P PT PT SPP A P P + T+
Sbjct: 441 APALTSVPAPAPAPTPTPTPVQPT-------SPPPGPVAQPTGPQPQSAGSTS------- 486
Query: 236 DRAPVRGPGSPPPPPAREDPDSPPGRPEDCAPPPAA 271
PV P PPP PA P PPG APP A
Sbjct: 487 --GPVPQPACPPPGPA-PHPTGPPGPIPVPAPPQIA 519
Score = 30.8 bits (68), Expect = 1.8
Identities = 14/42 (33%), Positives = 18/42 (42%)
Query: 2 LLRPRRPPPLAPPAPPSPASPDPEPRTPGDAPGTPPRRPASP 43
+ RP P + PAP +P P P P P P +P P
Sbjct: 436 MARPAAPALTSVPAPAPAPTPTPTPVQPTSPPPGPVAQPTGP 477
Score = 28.9 bits (63), Expect = 6.9
Identities = 26/86 (30%), Positives = 29/86 (33%), Gaps = 20/86 (23%)
Query: 8 PPPLAPPAPPSPASPDP---------EPRTPGDA------PGTPPRRPASPSALGELGLP 52
P P P P P SP P +P++ G P PP PA P G P
Sbjct: 452 PAPTPTPTPVQPTSPPPGPVAQPTGPQPQSAGSTSGPVPQPACPPPGPA-PHPTG----P 506
Query: 53 VSPGSAQRTPWSARETELLLGTLLQP 78
P P A T LL L P
Sbjct: 507 PGPIPVPAPPQIATSTSLLAAQSLVP 532
Score = 28.9 bits (63), Expect = 6.9
Identities = 18/53 (33%), Positives = 20/53 (37%), Gaps = 8/53 (15%)
Query: 4 RPRRPPPLAPPAPPSPASPDPEPRTPGDAPGTPPRRPASPSALGELGLPVSPG 56
+P PPP P P P P P P PP+ S S L L PG
Sbjct: 491 QPACPPPGPAPHPTGPPGPIPVP--------APPQIATSTSLLAAQSLVPPPG 535
>gi|149158690 HLA-B associated transcript-2 [Homo sapiens]
Length = 2157
Score = 53.9 bits (128), Expect = 2e-07
Identities = 75/281 (26%), Positives = 101/281 (35%), Gaps = 82/281 (29%)
Query: 9 PPLAPPAPPSPASPDPEPR--------TPGDAP--GTPPRRPASPSALGELGLPVSPGSA 58
PP P PP+P P P P PGD P G PP +P +P E
Sbjct: 398 PPETEPGPPAPKPPLPPPHRGPAGNWGPPGDYPDRGGPPCKPPAPEDEDE-------AWR 450
Query: 59 QRTPWSARETELLLGTLLQPAVWRALLLDRRQALPTYRRVSAALAQQQVRRTPAQCRRRY 118
QR S+ E L AV RA RR+ RR+ Q+ RR A C +
Sbjct: 451 QRRKQSSSEISL--------AVERA----RRRREEEERRM------QEERR--AACAEKL 490
Query: 119 KFLKDKFREAHGQPPGPFDEQIRKLMGLLGDNGRKRPRRRSPGSGRPQRARRPVPNAHAP 178
K L +KF G P + R + +P + A P P
Sbjct: 491 KRLDEKF----GAP-----------------DKRLKAEPAAPPAAPSTPAPPPAVPKELP 529
Query: 179 APSEPDATPLPTARDRDADPTWTLRFSPSPPKSADASPAPGSPPAP------APTALATC 232
AP P PT +P + +PP A ++P PG AP T+ +
Sbjct: 530 APPAPPPASAPTPETEPEEP------AQAPP--AQSTPTPGVAAAPTLVSGGGSTSSTSS 581
Query: 233 IPEDRAPVRGPGSPPPPPAREDPDSPPGRPEDCAPPPAAPP 273
+ +PV P P++E P+ P + PPP PP
Sbjct: 582 GSFEASPVE-----PQLPSKEGPE-----PPEEVPPPTTPP 612
Score = 50.1 bits (118), Expect = 3e-06
Identities = 73/295 (24%), Positives = 101/295 (34%), Gaps = 66/295 (22%)
Query: 5 PRRPPPLAPPAPPSPASP-DPEPRTPGDAPGTPPRRPASPSALGELGLPVSPGSAQRTPW 63
PRR P+ P PP+ P+P GD PP+ G+LG P + TP
Sbjct: 946 PRRAGPIKKPPPPTKVEELPPKPLEQGDETPKPPKPDPLKITKGKLGGP------KETPP 999
Query: 64 SARETELLLGTLLQPAVWRALLLDRRQALPTYRRVSAALAQQQVRRTPAQCRRRYK---F 120
+ L PA R + +Y RV P CR R + F
Sbjct: 1000 NGN---------LSPA-------PRLRRDYSYERVG-----------PTSCRGRGRGEYF 1032
Query: 121 LKDK-FREAHG-QPPGPFDEQIRKLMGLLGDNGR----------KRPRRRSPGSGRPQRA 168
+ + FR +G + G + R GD+GR PR R+ R + +
Sbjct: 1033 ARGRGFRGTYGGRGRGARSREFRSYREFRGDDGRGGGTGGPNHPPAPRGRTASETRSEGS 1092
Query: 169 R-RPVPNAHAPAPSEP-----DATPLPTARDRDADPTWTLRFSPSPPKSADASPAPGSPP 222
+P SE ++ P+ ++ TL P P P PG+PP
Sbjct: 1093 EYEEIPKRRRQRGSETGSETHESDLAPSDKEAPTPKEGTLTQVPLAP------PPPGAPP 1146
Query: 223 APAPTALA-----TCIPEDRAPVRGPGSPPPPPAREDPDSPPGRPEDCAPPPAAP 272
+PAP P RG G PPP SPP + PP P
Sbjct: 1147 SPAPARFTARGGRVFTPRGVPSRRGRGGGRPPPQVCPGWSPPAKSLAPKKPPTGP 1201
Score = 40.4 bits (93), Expect = 0.002
Identities = 46/159 (28%), Positives = 60/159 (37%), Gaps = 33/159 (20%)
Query: 131 QPPGPFDE-----QIRKLMGLLGDNGRKRPRRRSPGSGRPQRARRPVPNAHAPAPSEPDA 185
+PP P DE Q RK +R RRR R + RR A A
Sbjct: 438 KPPAPEDEDEAWRQRRKQSSSEISLAVERARRR-----REEEERRMQEERRAAC-----A 487
Query: 186 TPLPTARDRDADPTWTLRFSPSPPKSADASPAPGSPPAPAPTALATCIPEDRAPVRGPGS 245
L ++ P L+ P+ P +A ++PAP PPA P P
Sbjct: 488 EKLKRLDEKFGAPDKRLKAEPAAPPAAPSTPAP--PPA--------------VPKELPAP 531
Query: 246 PPPPPA-REDPDSPPGRPEDCAPPPAAPPSLNTALLQTL 283
P PPPA P++ P P APP + P+ A TL
Sbjct: 532 PAPPPASAPTPETEPEEPAQ-APPAQSTPTPGVAAAPTL 569
Score = 37.0 bits (84), Expect = 0.025
Identities = 32/99 (32%), Positives = 39/99 (39%), Gaps = 8/99 (8%)
Query: 155 PRRRSPGSGRPQRARRPVPNAHAPAPSEPDATPLPTARDRDADPT-WTLRFSPSPPKSAD 213
PR G+ ARR P A+ P+ + P D T W + S PKS+D
Sbjct: 40 PRHGLQSLGKVAIARRMPPPANLPSLKAENKGNDPNVSLVPKDGTGWASKQEQSDPKSSD 99
Query: 214 ASPA--PGSPPAPAPTALATCIPEDRAPVRGPGSPPPPP 250
AS A P S P PA P P R P +P P
Sbjct: 100 ASTAQPPESQPLPASQT-----PASNQPKRPPAAPENTP 133
Score = 36.6 bits (83), Expect = 0.033
Identities = 73/308 (23%), Positives = 107/308 (34%), Gaps = 49/308 (15%)
Query: 8 PPPL------APPAPPSPASPDP--EPRTPGDAP---GTP-PRRPASPSALGELGLPVSP 55
PPP APPAPP ++P P EP P AP TP P A+P+ + G S
Sbjct: 520 PPPAVPKELPAPPAPPPASAPTPETEPEEPAQAPPAQSTPTPGVAAAPTLVSGGG---ST 576
Query: 56 GSAQRTPWSARETELLLGTLLQPAVWRALLLDRRQALPTYRRVSAALAQQQVRRTPAQCR 115
S + A E L + P + +P + R+ P+Q
Sbjct: 577 SSTSSGSFEASPVEPQLPSKEGPEPPEEVPPPTTPPVPKVEPKGDGIG--PTRQPPSQGL 634
Query: 116 RRYKFLKDKFREAHGQPPGPFDEQIRKLMGLLGDNGRKRPRRRS-PGSGRPQRARRPVPN 174
K+ K PP +Q +L+ + ++ ++ S P + P +PV
Sbjct: 635 GYPKYQK-------SLPPRFQRQQQEQLLKQQQQHQWQQHQQGSAPPTPVPPSPPQPVTL 687
Query: 175 AHAPAPSEPDATPL----------PTARDRDADPTWTLRFSPSPPKSADA-SPAPGSPPA 223
PAP P P P + DP W + P+ P PP
Sbjct: 688 GAVPAPQAPPPPPKALYPGALGRPPPMPPMNFDPRWMMIPPYVDPRLLQGRPPLDFYPPG 747
Query: 224 PAPTALATCIPEDRAPVRGPGSPP----PPPAREDPDSPPGRP------EDCAPPPAAPP 273
P+ L +P +R+ G S P P + +PP P + PA P
Sbjct: 748 VHPSGL---VPRERSDSGGSSSEPFDRHAPAMLRERGTPPVDPKLAWVGDVFTATPAEPR 804
Query: 274 SLNTALLQ 281
L + L Q
Sbjct: 805 PLTSPLRQ 812
Score = 36.2 bits (82), Expect = 0.043
Identities = 66/247 (26%), Positives = 79/247 (31%), Gaps = 74/247 (29%)
Query: 30 GDAPGTP-PRRPASPSALGELGLPVSPGSAQRTPWSARETELLLGTLLQPAVWRALLLDR 88
G AP TP P P P LG + P +P + L G L +P + D
Sbjct: 670 GSAPPTPVPPSPPQPVTLGAVPAPQAPPPPPKA--------LYPGALGRPPPMPPMNFDP 721
Query: 89 R-QALPTYRRVSAALAQQQVRRTPAQCRRRYKFLKDKFREAHGQPPGPFDEQIRKLMGLL 147
R +P Y V L Q G+PP F GL+
Sbjct: 722 RWMMIPPY--VDPRLLQ-------------------------GRPPLDFYPPGVHPSGLV 754
Query: 148 GDNGRKRPRRRSPGSGRPQRARRPVPNAHAPAPSEPDATPLPTARDRDADPTWTLRFSPS 207
PR RS G + HAPA TP P
Sbjct: 755 -------PRERSDSGGSSSEPF----DRHAPAMLRERGTP------------------PV 785
Query: 208 PPKSA---DASPAPGSPPAPAPTALATCIPEDRAPVRG--PGSPPPPPAREDPDSPPGRP 262
PK A D A + P P + L ED +R P PPPPP S PG P
Sbjct: 786 DPKLAWVGDVFTATPAEPRPLTSPLRQAADEDDKGMRSETPPVPPPPPYLA---SYPGFP 842
Query: 263 EDCAPPP 269
E+ AP P
Sbjct: 843 ENGAPGP 849
Score = 35.4 bits (80), Expect = 0.074
Identities = 84/341 (24%), Positives = 108/341 (31%), Gaps = 79/341 (23%)
Query: 5 PRRPPPLAPPAP------PSPASPDPEPRT--PGDAPGTPPRRP--------------AS 42
P P P +PP P P+P +P P P+ PG A G PP P
Sbjct: 673 PPTPVPPSPPQPVTLGAVPAPQAPPPPPKALYPG-ALGRPPPMPPMNFDPRWMMIPPYVD 731
Query: 43 PSAL-GELGLPVSPGSAQRTPWSARETELLLGTLLQPAVWRALLLDRRQALPTYRRVSAA 101
P L G L P + RE G+ +P A + R + P A
Sbjct: 732 PRLLQGRPPLDFYPPGVHPSGLVPRERSDSGGSSSEPFDRHAPAMLRERGTPPVDP-KLA 790
Query: 102 LAQQQVRRTPAQCRRRYKFLK------DKFREAHGQPPGPFDEQIRKLMGLLGDNGRK-- 153
TPA+ R L+ DK + P P + G +NG
Sbjct: 791 WVGDVFTATPAEPRPLTSPLRQAADEDDKGMRSETPPVPPPPPYLASYPGF-PENGAPGP 849
Query: 154 ------------RPRRRSPGSGRPQRARRPVPNAHAPAPSEPDATPLPTARDRDADPTWT 201
RP PGS + + P P P T P A + A +
Sbjct: 850 PISRFPLEEPGPRPLPWPPGSDEVAKIQTPPPKKEPPKEETAQLTG-PEAGRKPARGVGS 908
Query: 202 LRFSPSPPKSADAS-----PAPGSPPAPAPTALATCIPEDRAPVRGPGSPP--------P 248
P PP+ + P PGS P PE+ PG+PP P
Sbjct: 909 GGQGPPPPRRESRTETRWGPRPGSSRRGIP-------PEE------PGAPPRRAGPIKKP 955
Query: 249 PPAREDPDSPPGRPE--DCAPPPAAPPSLNTALLQTLGHLG 287
PP + + PP E D P P P L T G LG
Sbjct: 956 PPPTKVEELPPKPLEQGDETPKPPKPDPLKI----TKGKLG 992
Score = 34.7 bits (78), Expect = 0.13
Identities = 23/73 (31%), Positives = 25/73 (34%), Gaps = 8/73 (10%)
Query: 209 PKSADASPAPGSPPAPAPTALATCIPEDRAPVRGPGSPPPPPAREDPD-------SPPGR 261
P AD SP + PT R P PG P P P P PPG
Sbjct: 370 PPEADGKKG-NSPNSEPPTPKTAWAETSRPPETEPGPPAPKPPLPPPHRGPAGNWGPPGD 428
Query: 262 PEDCAPPPAAPPS 274
D PP PP+
Sbjct: 429 YPDRGGPPCKPPA 441
Score = 33.9 bits (76), Expect = 0.22
Identities = 34/119 (28%), Positives = 45/119 (37%), Gaps = 22/119 (18%)
Query: 149 DNGRKRPRRRSPGSGRPQRA---RRPVPNAHAPAPSEPDATPLPTARDRDADPTWTLRFS 205
++GR + G Q A RP P A + P++ P PT + A+ +
Sbjct: 345 EDGRDSDEEGAEGHRDSQSASGEERP-PEADGKKGNSPNSEP-PTPKTAWAETS------ 396
Query: 206 PSPPKSADASPAPGSPPAPAPTALATCIPEDRAPVRGPGSPPPPPAREDPDSPPGRPED 264
PP++ PAP PP P P R P G P P R P P PED
Sbjct: 397 -RPPETEPGPPAP-KPPLPPP---------HRGPAGNWGPPGDYPDRGGPPCKPPAPED 444
Score = 31.2 bits (69), Expect = 1.4
Identities = 62/291 (21%), Positives = 87/291 (29%), Gaps = 47/291 (16%)
Query: 8 PPPLAPPAP---PSPASPDPEPRTPGDAPGTPPRR----PASPSALGELGLPVSPGSAQR 60
PPP P P P+P P PR G PP R PS L E L Q
Sbjct: 262 PPPYGPQGPYRYPTPDGPSRFPRVAGPRGSGPPMRLVEPVGRPSILKEDNLKEFDQLDQE 321
Query: 61 TP--WSARETELLLGTLLQPAVWRALLLDRRQALPTYRRVSAALAQQQVRRTPAQCRRRY 118
W+ E+ L+ + + +R +A +++ +
Sbjct: 322 NDDGWAGAHEEVDYTEKLKFSDEEDGRDSDEEGAEGHRDSQSASGEERPPEADGK----- 376
Query: 119 KFLKDKFREAHGQPPGPFDEQIRKLMGLLGDNGRKRPRRRSPGSGRPQRARRPVPNAH-- 176
K + +PP P RP PG P + P+P H
Sbjct: 377 -----KGNSPNSEPPTPKTAWAE----------TSRPPETEPG---PPAPKPPLPPPHRG 418
Query: 177 -----APAPSEPD--ATPLPTARDRDADPTWTLRFSPSPPKSADASPAPGSPPAPAPTAL 229
P PD P D D W R S + + A +
Sbjct: 419 PAGNWGPPGDYPDRGGPPCKPPAPEDEDEAWRQRRKQSSSEISLAVERARRRREEEERRM 478
Query: 230 -----ATCIPEDRAPVRGPGSPPPPPAREDPDSPPGRPEDCAPPPAAPPSL 275
A C + + G+ P + +P +PP P APPPA P L
Sbjct: 479 QEERRAACAEKLKRLDEKFGA-PDKRLKAEPAAPPAAPSTPAPPPAVPKEL 528
Score = 30.8 bits (68), Expect = 1.8
Identities = 22/66 (33%), Positives = 29/66 (43%), Gaps = 3/66 (4%)
Query: 130 GQPPGPFDEQIRKLMGLLGDNGRKRPRRRSPGSGRPQRARRP--VPNAHAPAPSEPDATP 187
G PP P + G + R P RR G GRP P P A + AP +P P
Sbjct: 1143 GAPPSPAPARFTARGGRVF-TPRGVPSRRGRGGGRPPPQVCPGWSPPAKSLAPKKPPTGP 1201
Query: 188 LPTARD 193
LP +++
Sbjct: 1202 LPPSKE 1207
Score = 29.6 bits (65), Expect = 4.1
Identities = 22/58 (37%), Positives = 23/58 (39%), Gaps = 16/58 (27%)
Query: 5 PRRPPPLAP------------PAPPSPASPDPEPRTP-GDAPG--TPPRRPASPSALG 47
PRRPPP AP P PP P + RT G PG P RP P G
Sbjct: 1707 PRRPPP-APHDGDRKELPREQPLPPGPIGTERSQRTDRGTEPGPIRPSHRPGPPVQFG 1763
Score = 29.6 bits (65), Expect = 4.1
Identities = 17/45 (37%), Positives = 19/45 (42%), Gaps = 2/45 (4%)
Query: 218 PGSPPAPAPTALATCIPEDRAPVRGPGSPPPPPAREDPDSPPGRP 262
P PPAP P +L P + P PP P R P P RP
Sbjct: 1998 PAPPPAPPPLSLLPVGPALQPPSLAVRPPPAPATRVLPS--PARP 2040
>gi|4826998 splicing factor proline/glutamine rich (polypyrimidine
tract binding protein associated) [Homo sapiens]
Length = 707
Score = 53.9 bits (128), Expect = 2e-07
Identities = 49/148 (33%), Positives = 61/148 (41%), Gaps = 15/148 (10%)
Query: 132 PPGPFDEQIRKLMGL-LGDNGRKRPRRRSPGSGRPQRARRPVPNAHAPAPSEPDATPLPT 190
PPG Q R MG G +G K P P + Q+ P P P +P P P
Sbjct: 35 PPGMGLNQNRGPMGPGPGQSGPKPPIPPPPPHQQQQQPPPQQPPPQQPPPHQPPPHPQPH 94
Query: 191 ARDRDADPTWTLRFSPSPPKSADASPAPG---SPPAPAPTALATCIPEDRAPVRGPG-SP 246
+ + P + S P + PAPG +PPA + AT P GPG +P
Sbjct: 95 QQQQPPPPP---QDSSKPVVAQGPGPAPGVGSAPPASSSAPPATPPTSGAPPGSGPGPTP 151
Query: 247 PPPPAREDPDSPPGRPEDCAPPPAAPPS 274
PPPA +PPG APPP P S
Sbjct: 152 TPPPA--VTSAPPG-----APPPTPPSS 172
Score = 47.8 bits (112), Expect = 1e-05
Identities = 43/165 (26%), Positives = 60/165 (36%), Gaps = 39/165 (23%)
Query: 129 HGQPPGPFDEQIRKLMGLLGDNGRKRPRRRSPGSGRPQRARRPVP-----NAHAPAPSEP 183
H PP P Q +++P S +P A+ P P +A + S P
Sbjct: 85 HQPPPHPQPHQ------------QQQPPPPPQDSSKPVVAQGPGPAPGVGSAPPASSSAP 132
Query: 184 DATPLPTARDRDADPTWTLRFSPSPPKSADASPAPGSPPAPAPTALATCIPEDRAPVRGP 243
ATP + + P T P+PP + ++P PP P + + T P+
Sbjct: 133 PATPPTSGAPPGSGPGPT----PTPPPAVTSAPPGAPPPTPPSSGVPTTPPQ-------A 181
Query: 244 GSPPPPPAR-----------EDPDSPPGRPEDCAPPPAAPPSLNT 277
G PPPPPA P P G P P P L+T
Sbjct: 182 GGPPPPPAAVPGPGPGPKQGPGPGGPKGGKMPGGPKPGGGPGLST 226
Score = 35.8 bits (81), Expect = 0.057
Identities = 25/72 (34%), Positives = 31/72 (43%), Gaps = 17/72 (23%)
Query: 5 PRRPPPLAPPAPPSP---ASPDPEPRT---------PGDAPGTPPRRPASPSALGELGLP 52
P++PPP PP P P P P P+ PG APG PAS SA P
Sbjct: 79 PQQPPPHQPPPHPQPHQQQQPPPPPQDSSKPVVAQGPGPAPGVGSAPPASSSA-----PP 133
Query: 53 VSPGSAQRTPWS 64
+P ++ P S
Sbjct: 134 ATPPTSGAPPGS 145
Score = 33.1 bits (74), Expect = 0.37
Identities = 22/60 (36%), Positives = 26/60 (43%), Gaps = 12/60 (20%)
Query: 9 PPLAPP---APPSPA---SPDPEPRTPGDAPGTPPRRPASPSALGELGLPVSPGSAQRTP 62
PP PP APP +P P P PG PP P PS+ G+P +P A P
Sbjct: 132 PPATPPTSGAPPGSGPGPTPTPPPAVTSAPPGAPP--PTPPSS----GVPTTPPQAGGPP 185
Score = 32.7 bits (73), Expect = 0.48
Identities = 22/61 (36%), Positives = 25/61 (40%), Gaps = 4/61 (6%)
Query: 5 PRRPPPLAPPAPPSPASPDPEP-RTPGDAPGTPP--RRPASPSALGELGLPVSPGSAQRT 61
P PP P PP A P P P G PG P + P P G GL +PG +
Sbjct: 175 PTTPPQAGGPPPPPAAVPGPGPGPKQGPGPGGPKGGKMPGGPKPGGGPGLS-TPGGHPKP 233
Query: 62 P 62
P
Sbjct: 234 P 234
Score = 32.0 bits (71), Expect = 0.82
Identities = 17/40 (42%), Positives = 17/40 (42%), Gaps = 4/40 (10%)
Query: 8 PPPLAPPAPPSPASPDPE----PRTPGDAPGTPPRRPASP 43
PPP APP P P P TP A G PP A P
Sbjct: 153 PPPAVTSAPPGAPPPTPPSSGVPTTPPQAGGPPPPPAAVP 192
Score = 30.8 bits (68), Expect = 1.8
Identities = 17/58 (29%), Positives = 24/58 (41%), Gaps = 1/58 (1%)
Query: 8 PPPLAPPAPPSPASPDPEPRTPGDAPGTPPRRPASPSALGELGLPVSPGSAQRTPWSA 65
PP PP P P P P P+ PP + +S + + G +PG P S+
Sbjct: 73 PPQQPPPQQPPPHQPPPHPQPHQQQQPPPPPQDSSKPVVAQ-GPGPAPGVGSAPPASS 129
Score = 29.3 bits (64), Expect = 5.3
Identities = 16/38 (42%), Positives = 19/38 (50%), Gaps = 3/38 (7%)
Query: 8 PPPLAPPAPPS--PASPDPEPRTPGDAPGTPPRRPASP 43
P P PPA S P +P P P + G P TPP+ P
Sbjct: 149 PTPTPPPAVTSAPPGAPPPTPPSSG-VPTTPPQAGGPP 185
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.315 0.136 0.428
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 21,454,490
Number of Sequences: 37866
Number of extensions: 1715112
Number of successful extensions: 50037
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 1043
Number of HSP's successfully gapped in prelim test: 1856
Number of HSP's that attempted gapping in prelim test: 13945
Number of HSP's gapped (non-prelim): 23145
length of query: 341
length of database: 18,247,518
effective HSP length: 103
effective length of query: 238
effective length of database: 14,347,320
effective search space: 3414662160
effective search space used: 3414662160
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.