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Search of human proteins with 70608170
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|70608170 H6 family homeobox 2 [Homo sapiens]
(273 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|70608170 H6 family homeobox 2 [Homo sapiens] 563 e-161
gi|157743259 H6 family homeobox 3 [Homo sapiens] 162 4e-40
gi|116805350 homeo box (H6 family) 1 [Homo sapiens] 142 4e-34
gi|7706621 T-cell leukemia homeobox 2 [Homo sapiens] 105 6e-23
gi|50355978 T-cell leukemia homeobox 3 [Homo sapiens] 91 8e-19
gi|4502365 NK3 homeobox 2 [Homo sapiens] 91 1e-18
gi|210147470 NK2 transcription factor related, locus 6 [Homo sap... 89 4e-18
gi|148746211 NK2 transcription factor related, locus 3 [Homo sap... 86 3e-17
gi|5031757 T-cell leukemia homeobox 1 [Homo sapiens] 85 8e-17
gi|31377777 NK2 homeobox 8 [Homo sapiens] 83 2e-16
gi|14149728 BarH-like homeobox 1 [Homo sapiens] 82 5e-16
gi|39930383 BarH-like homeobox 2 [Homo sapiens] 82 5e-16
gi|118582284 msh homeobox 1 [Homo sapiens] 81 1e-15
gi|4758090 NK2 transcription factor related, locus 5 [Homo sapiens] 80 1e-15
gi|28912912 NK6 transcription factor related, locus 2 [Homo sapi... 80 1e-15
gi|226437602 NK1 homeobox 2 [Homo sapiens] 80 2e-15
gi|239755439 PREDICTED: NK1 homeobox 2 [Homo sapiens] 80 2e-15
gi|239749920 PREDICTED: NK1 homeobox 2 [Homo sapiens] 80 2e-15
gi|239744223 PREDICTED: NK1 homeobox 2 [Homo sapiens] 80 2e-15
gi|24497526 homeobox B1 [Homo sapiens] 80 2e-15
gi|19923352 NK3 homeobox 1 [Homo sapiens] 79 3e-15
gi|111120318 NK6 transcription factor related, locus 1 [Homo sap... 79 6e-15
gi|4505401 NK2 transcription factor related, locus 2 [Homo sapiens] 78 7e-15
gi|27886557 msh homeobox 2 [Homo sapiens] 78 9e-15
gi|239748344 PREDICTED: NK1 homeobox 1 [Homo sapiens] 77 2e-14
gi|147901462 brain specific homeobox [Homo sapiens] 77 2e-14
gi|84105335 mesenchyme homeobox 2 [Homo sapiens] 77 2e-14
gi|239742243 PREDICTED: HPX-153 homeobox [Homo sapiens] 77 2e-14
gi|239753784 PREDICTED: NK1 homeobox 1 [Homo sapiens] 76 3e-14
gi|157426823 NK2 homeobox 4 [Homo sapiens] 73 3e-13
>gi|70608170 H6 family homeobox 2 [Homo sapiens]
Length = 273
Score = 563 bits (1452), Expect = e-161
Identities = 273/273 (100%), Positives = 273/273 (100%)
Query: 1 MGSKEDAGKGCPAAGGVSSFTIQSILGGGPSEAPREPVGWPARKRSLSVSSEEEEPDDGW 60
MGSKEDAGKGCPAAGGVSSFTIQSILGGGPSEAPREPVGWPARKRSLSVSSEEEEPDDGW
Sbjct: 1 MGSKEDAGKGCPAAGGVSSFTIQSILGGGPSEAPREPVGWPARKRSLSVSSEEEEPDDGW 60
Query: 61 KAPACFCPDQHGPKEQGPKHHPPIPFPCLGTPKGSGGSGPGGLERTPFLSPSHSDFKEEK 120
KAPACFCPDQHGPKEQGPKHHPPIPFPCLGTPKGSGGSGPGGLERTPFLSPSHSDFKEEK
Sbjct: 61 KAPACFCPDQHGPKEQGPKHHPPIPFPCLGTPKGSGGSGPGGLERTPFLSPSHSDFKEEK 120
Query: 121 ERLLPAGSPSPGSERPRDGGAERQAGAAKKKTRTVFSRSQVYQLESTFDMKRYLSSSERA 180
ERLLPAGSPSPGSERPRDGGAERQAGAAKKKTRTVFSRSQVYQLESTFDMKRYLSSSERA
Sbjct: 121 ERLLPAGSPSPGSERPRDGGAERQAGAAKKKTRTVFSRSQVYQLESTFDMKRYLSSSERA 180
Query: 181 CLASSLQLTETQVKTWFQNRRNKWKRQLSAELEAANMAHASAQTLVSMPLVFRDSSLLRV 240
CLASSLQLTETQVKTWFQNRRNKWKRQLSAELEAANMAHASAQTLVSMPLVFRDSSLLRV
Sbjct: 181 CLASSLQLTETQVKTWFQNRRNKWKRQLSAELEAANMAHASAQTLVSMPLVFRDSSLLRV 240
Query: 241 PVPRSLAFPAPLYYPGSNLSALPLYNLYNKLDY 273
PVPRSLAFPAPLYYPGSNLSALPLYNLYNKLDY
Sbjct: 241 PVPRSLAFPAPLYYPGSNLSALPLYNLYNKLDY 273
>gi|157743259 H6 family homeobox 3 [Homo sapiens]
Length = 357
Score = 162 bits (409), Expect = 4e-40
Identities = 88/152 (57%), Positives = 111/152 (73%), Gaps = 13/152 (8%)
Query: 126 AGSPSPGSERPRDGGA--ERQAGAAKKKTRTVFSRSQVYQLESTFDMKRYLSSSERACLA 183
A + +PG+E + G E++ KKKTRTVFSRSQV+QLESTFDMKRYLSSSERA LA
Sbjct: 202 AAAATPGAEDWKKGAESPEKKPACRKKKTRTVFSRSQVFQLESTFDMKRYLSSSERAGLA 261
Query: 184 SSLQLTETQVKTWFQNRRNKWKRQLSAELEAANMAHASAQTLVSMPLVFRDSSLLR---- 239
+SL LTETQVK WFQNRRNKWKRQL+AELEAAN++HA+AQ +V +P+++ ++S
Sbjct: 262 ASLHLTETQVKIWFQNRRNKWKRQLAAELEAANLSHAAAQRIVRVPILYHENSAAEGAAA 321
Query: 240 ----VPVPRS---LAFPAPLYYPGSNLSALPL 264
PVP S L FP P+YY +S++PL
Sbjct: 322 AAAGAPVPVSQPLLTFPHPVYYSHPVVSSVPL 353
>gi|116805350 homeo box (H6 family) 1 [Homo sapiens]
Length = 348
Score = 142 bits (357), Expect = 4e-34
Identities = 82/159 (51%), Positives = 102/159 (64%), Gaps = 7/159 (4%)
Query: 97 GSGPGGLERTPFLSPSHSDFKEEKERLLPAGSPSPGSERPRDGGAERQAGAAKKKTRTVF 156
G GPG ++R + +E A P+ E G G KKKTRTVF
Sbjct: 154 GPGPGAVQREAAELAARGPAAGTEEASELAEVPAAAGETRGGVGV---GGGRKKKTRTVF 210
Query: 157 SRSQVYQLESTFDMKRYLSSSERACLASSLQLTETQVKTWFQNRRNKWKRQLSAELEAAN 216
SRSQV+QLESTFD+KRYLSS+ERA LA+SLQLTETQVK WFQNRRNKWKRQL+AELEAA+
Sbjct: 211 SRSQVFQLESTFDLKRYLSSAERAGLAASLQLTETQVKIWFQNRRNKWKRQLAAELEAAS 270
Query: 217 MAHASAQTLVSMPLVFRDSSLLRVPVPRSLAFPAPLYYP 255
++ AQ LV +P+++ +S P + PA L +P
Sbjct: 271 LSPPGAQRLVRVPVLYHESP----PAAAAAGPPATLPFP 305
>gi|7706621 T-cell leukemia homeobox 2 [Homo sapiens]
Length = 284
Score = 105 bits (261), Expect = 6e-23
Identities = 78/191 (40%), Positives = 102/191 (53%), Gaps = 18/191 (9%)
Query: 78 PKHHP-PIPFPCLGTPKGSGGSGPGGLERTPFLSPSHSDFKEE--KERLLPAGSPSPGSE 134
P H P P+P P G P G SG GG L+ D K+RL A SP G+
Sbjct: 84 PAHRPLPVPPPAGGAPAVPGPSGLGGAGGLAGLTFPWMDSGRRFAKDRLTAALSPFSGTR 143
Query: 135 RPRDGGAERQAGAAKKKTRTVFSRSQVYQLESTFDMKRYLSSSERACLASSLQLTETQVK 194
R R +KK RT FSRSQV +LE F ++YL+S+ERA LA +L++T+ QVK
Sbjct: 144 RIGHPYQNRTP-PKRKKPRTSFSRSQVLELERRFLRQKYLASAERAALAKALRMTDAQVK 202
Query: 195 TWFQNRRNKWKRQLSAELEAANMAHASAQTLVSMPLVFRDSSL---LRVPVPRSLAFPAP 251
TWFQNRR KW+RQ + E EA H + + L+ + + +L LR P+P P P
Sbjct: 203 TWFQNRRTKWRRQTAEEREAER--HRAGRLLLHL----QQDALPRPLRPPLP-----PDP 251
Query: 252 LYYPGSNLSAL 262
L S+L AL
Sbjct: 252 LCLHNSSLFAL 262
>gi|50355978 T-cell leukemia homeobox 3 [Homo sapiens]
Length = 291
Score = 91.3 bits (225), Expect = 8e-19
Identities = 55/134 (41%), Positives = 77/134 (57%), Gaps = 5/134 (3%)
Query: 82 PPIPFPCLGTPKGSGGSGPGGLERTPFLSPSHSDFKEEKERLLPAGSPSPGSERPRDGGA 141
PP+P P S GGL P++ S + K+R A + +P + R G
Sbjct: 102 PPLPSALPAMPSVPTVSSLGGLN-FPWMESSR---RFVKDRFTAAAALTPFTVTRRIGHP 157
Query: 142 -ERQAGAAKKKTRTVFSRSQVYQLESTFDMKRYLSSSERACLASSLQLTETQVKTWFQNR 200
+ + +KK RT FSR Q+ +LE F ++YL+S+ERA LA SL++T+ QVKTWFQNR
Sbjct: 158 YQNRTPPKRKKPRTSFSRVQICELEKRFHRQKYLASAERAALAKSLKMTDAQVKTWFQNR 217
Query: 201 RNKWKRQLSAELEA 214
R KW+RQ + E EA
Sbjct: 218 RTKWRRQTAEEREA 231
>gi|4502365 NK3 homeobox 2 [Homo sapiens]
Length = 333
Score = 90.5 bits (223), Expect = 1e-18
Identities = 65/168 (38%), Positives = 88/168 (52%), Gaps = 42/168 (25%)
Query: 94 GSGGSGPGGLERTPFLSPSHSDFKEEKERLLPAGSPSPGSERPRDGGAERQAGAAKKKTR 153
G GGSGP G+ +EE+E P + +PR KK++R
Sbjct: 183 GGGGSGPAGVA------------EEEEE---------PAAPKPR-----------KKRSR 210
Query: 154 TVFSRSQVYQLESTFDMKRYLSSSERACLASSLQLTETQVKTWFQNRRNKWK-RQLSAEL 212
FS +QV++LE F+ +RYLS ERA LA+SL+LTETQVK WFQNRR K K RQ++A+L
Sbjct: 211 AAFSHAQVFELERRFNHQRYLSGPERADLAASLKLTETQVKIWFQNRRYKTKRRQMAADL 270
Query: 213 EAANMAHASAQTLVSMPLVFRDSSLLRVP-----VPRSLAFPAPLYYP 255
+A A A V++ ++ RD +P P L YYP
Sbjct: 271 ----LASAPAAKKVAVKVLVRDDQRQYLPGEVLRPPSLLPLQPSYYYP 314
>gi|210147470 NK2 transcription factor related, locus 6 [Homo
sapiens]
Length = 219
Score = 89.0 bits (219), Expect = 4e-18
Identities = 53/116 (45%), Positives = 69/116 (59%), Gaps = 3/116 (2%)
Query: 137 RDGGAERQAGAAKKKTRTVFSRSQVYQLESTFDMKRYLSSSERACLASSLQLTETQVKTW 196
R G +E+ ++K R +FS++QV LE F +RYLS+ ER LAS+LQLT TQVK W
Sbjct: 38 RGGRSEQPKARQRRKPRVLFSQAQVLALERRFKQQRYLSAPEREHLASALQLTSTQVKIW 97
Query: 197 FQNRRNKWKRQ-LSAELEAANMAHASAQTLVSMPLVFRDSSLLRVPVPRSLAFPAP 251
FQNRR K KRQ LE A H V++P++ RD P P + AFP+P
Sbjct: 98 FQNRRYKCKRQRQDKSLELA--GHPLTPRRVAVPVLVRDGKPCLGPGPGAPAFPSP 151
>gi|148746211 NK2 transcription factor related, locus 3 [Homo
sapiens]
Length = 364
Score = 86.3 bits (212), Expect = 3e-17
Identities = 70/232 (30%), Positives = 103/232 (44%), Gaps = 16/232 (6%)
Query: 42 ARKRSLSVSSEEEEPDDGWKAP---ACFCPDQHGPKEQGPKHHPPIPFPCLGTPKGSGGS 98
A S EE+E D+G K + D HG P+ + + T S
Sbjct: 50 AEGTQFSDGGEEDEEDEGEKLSYLNSLAAADGHGDSGLCPQGY-------VHTVLRDSCS 102
Query: 99 GPGGLERTPFLSPSHSDFKEEKERLLPAGSPSPGSERPRDGGAERQAGAAKKKTRTVFSR 158
P E P + S + ++ L +E +ER +++K R +FS+
Sbjct: 103 EPKEHEEEPEVVRDRSQKSCQLKKSLETAGDCKAAEE-----SERPKPRSRRKPRVLFSQ 157
Query: 159 SQVYQLESTFDMKRYLSSSERACLASSLQLTETQVKTWFQNRRNKWKRQ-LSAELEAANM 217
+QV++LE F +RYLS+ ER LASSL+LT TQVK WFQNRR K KRQ LE
Sbjct: 158 AQVFELERRFKQQRYLSAPEREHLASSLKLTSTQVKIWFQNRRYKCKRQRQDKSLELGAH 217
Query: 218 AHASAQTLVSMPLVFRDSSLLRVPVPRSLAFPAPLYYPGSNLSALPLYNLYN 269
A V++P++ RD P ++ P + + ++ P Y N
Sbjct: 218 APPPPPRRVAVPVLVRDGKPCVTPSAQAYGAPYSVGASAYSYNSFPAYGYGN 269
>gi|5031757 T-cell leukemia homeobox 1 [Homo sapiens]
Length = 330
Score = 84.7 bits (208), Expect = 8e-17
Identities = 77/258 (29%), Positives = 103/258 (39%), Gaps = 51/258 (19%)
Query: 2 GSKEDAGKGCPAAGG--------VSSFTIQSILGGGPSEAPREPVGWPARKRSLSVSSEE 53
G+ G G PA GG S+ + L GGP P G +LS +
Sbjct: 75 GTGGPGGPGGPAGGGGACSMGPLTGSYNVNMALAGGPG--PGGGGGSSGGAGALSAAGVI 132
Query: 54 EEPDDGWKAPACFCPDQHGPKEQGPKHHPPIPFPCLGTPKGSGGSGPGGLERTPFLSPSH 113
P H P H P+ P G L F
Sbjct: 133 RVP-------------AHRPLAGAVAHPQPLATGLPTVPSVPAMPGVNNLTGLTF-PWME 178
Query: 114 SDFKEEKERLLPAGSPSPGSERPRDGGAERQAGAAKKKTRTVFSRSQVYQLESTFDMKRY 173
S+ + K+R G P P+ KKK RT F+R Q+ +LE F ++Y
Sbjct: 179 SNRRYTKDRF--TGHPYQNRTPPK-----------KKKPRTSFTRLQICELEKRFHRQKY 225
Query: 174 LSSSERACLASSLQLTETQVKTWFQNRRNKWKRQLSAELEAAN--------------MAH 219
L+S+ERA LA +L++T+ QVKTWFQNRR KW+RQ + E EA
Sbjct: 226 LASAERAALAKALKMTDAQVKTWFQNRRTKWRRQTAEEREAERQQANRILLQLQQEAFQK 285
Query: 220 ASAQTLVSMPLVFRDSSL 237
+ AQ L + PL +SSL
Sbjct: 286 SLAQPLPADPLCVHNSSL 303
>gi|31377777 NK2 homeobox 8 [Homo sapiens]
Length = 239
Score = 83.2 bits (204), Expect = 2e-16
Identities = 74/223 (33%), Positives = 100/223 (44%), Gaps = 46/223 (20%)
Query: 70 QHGPKEQGPKHHPPIPFPCLGTPKGSGGSGPGGLERTPFLSPSHSDFKEEKERLLPAGSP 129
QH P+ + P+ P P PC G P E + SP S + P+ P
Sbjct: 23 QHLPRRE-PEPRAPQPDPCAAWLDSERGHYPSSDESSLETSPPDSSQR-------PSARP 74
Query: 130 -SPGSERPRDGGAERQAGAAKKKTRTVFSRSQVYQLESTFDMKRYLSSSERACLASSLQL 188
SPGS+ + +KK R +FS++Q +LE F +RYLS+ ER LAS L+L
Sbjct: 75 ASPGSDAEK-----------RKKRRVLFSKAQTLELERRFRQQRYLSAPEREQLASLLRL 123
Query: 189 TETQVKTWFQNRRNKWKRQL------SAELEAANMAHASAQTL--VSMPLVFRD------ 234
T TQVK WFQN R K KR S +L A+ HA+ L V +P++ RD
Sbjct: 124 TPTQVKIWFQNHRYKLKRARAPGAAESPDLAASAELHAAPGLLRRVVVPVLVRDGQPCGG 183
Query: 235 ---------SSLLRVPVPRSLAFPAPLY---YPGSNLSALPLY 265
++ + P + A P P Y PGS L P Y
Sbjct: 184 GGGGEVGTAAAQEKCGAPPAAACPLPGYPAFGPGSALGLFPAY 226
>gi|14149728 BarH-like homeobox 1 [Homo sapiens]
Length = 327
Score = 82.0 bits (201), Expect = 5e-16
Identities = 57/153 (37%), Positives = 79/153 (51%), Gaps = 31/153 (20%)
Query: 110 SPSHSDFKEEKERLLPAGSPSPGSERPRDGGAERQAGAAKKKTRTVFSRSQVYQLESTFD 169
S S KEE +R + + SP + +K RT F+ Q+ QLE +F+
Sbjct: 150 SDSEYKVKEEGDREISSSRDSPPVRLKKP-----------RKARTAFTDHQLAQLERSFE 198
Query: 170 MKRYLSSSERACLASSLQLTETQVKTWFQNRRNKWKRQLSAELEAANMAHASAQTLVSMP 229
++YLS +R LA+SL LT+TQVKTW+QNRR KWKRQ + LE +A A
Sbjct: 199 RQKYLSVQDRMELAASLNLTDTQVKTWYQNRRTKWKRQTAVGLEL--LAEAG-------- 248
Query: 230 LVFRDSSLLRVPVPRSLAFPAPLYYPGSNLSAL 262
S+L R+ FP+P +YP S +S L
Sbjct: 249 ---NYSALQRM-------FPSPYFYPQSLVSNL 271
>gi|39930383 BarH-like homeobox 2 [Homo sapiens]
Length = 387
Score = 82.0 bits (201), Expect = 5e-16
Identities = 52/141 (36%), Positives = 77/141 (54%), Gaps = 17/141 (12%)
Query: 117 KEEKERLLPAGSPSPG--SERPRDGGAERQAGAAKKKTRTVFSRSQVYQLESTFDMKRYL 174
KEE +R + + SP +++PR K RT FS Q+ QLE +F+ ++YL
Sbjct: 211 KEEGDREITSSRESPPVRAKKPR-------------KARTAFSDHQLNQLERSFERQKYL 257
Query: 175 SSSERACLASSLQLTETQVKTWFQNRRNKWKRQLSAELEAANMA--HASAQTLVSMPLVF 232
S +R LA++L LT+TQVKTW+QNRR KWKRQ + LE A +++ Q + P +
Sbjct: 258 SVQDRMDLAAALNLTDTQVKTWYQNRRTKWKRQTAVGLELLAEAGNYSALQRMFPSPYFY 317
Query: 233 RDSSLLRVPVPRSLAFPAPLY 253
S L + + A A +Y
Sbjct: 318 HPSLLGSMDSTTAAAAAAAMY 338
>gi|118582284 msh homeobox 1 [Homo sapiens]
Length = 303
Score = 80.9 bits (198), Expect = 1e-15
Identities = 85/261 (32%), Positives = 107/261 (40%), Gaps = 17/261 (6%)
Query: 5 EDAGKGCPAAGGVSSFTIQSILGGGPSEAPREPVGWPARKRSLSVSSEEEEPDDGWKAPA 64
ED+ G PA GG + A E P SL S E D K A
Sbjct: 17 EDSAFGKPAGGGAGQAPSAAAATAAAMGADEEGAK-PKVSPSLLPFSVEALMADHRKPGA 75
Query: 65 ---CFCPDQHGPKEQGPKHHPPIPFPCLGTPKGSGGSGP------GGLERTPFLSPSHSD 115
P + G +P LG P P GGL + P + ++
Sbjct: 76 KESALAPSEGVQAAGGSAQPLGVPPGSLGAPDAPSSPRPLGHFSVGGLLKLPEDALVKAE 135
Query: 116 FKEEKERLLPAGSPS---PGSERPRDGGAERQAGAAKKKTRTVFSRSQVYQLESTFDMKR 172
E+ ER SP P + R + +K RT F+ +Q+ LE F K+
Sbjct: 136 SPEKPERTPWMQSPRFSPPPARRLSPPACTLRKHKTNRKPRTPFTTAQLLALERKFRQKQ 195
Query: 173 YLSSSERACLASSLQLTETQVKTWFQNRRNKWKRQLSAELEAANMAHASAQTLVSMPLVF 232
YLS +ERA +SSL LTETQVK WFQNRR K KR AELE MA A+ ++ P F
Sbjct: 196 YLSIAERAEFSSSLSLTETQVKIWFQNRRAKAKRLQEAELEKLKMA---AKPMLP-PAAF 251
Query: 233 RDSSLLRVPVPRSLAFPAPLY 253
S L P + A A LY
Sbjct: 252 GLSFPLGGPAAVAAAAGASLY 272
>gi|4758090 NK2 transcription factor related, locus 5 [Homo sapiens]
Length = 324
Score = 80.5 bits (197), Expect = 1e-15
Identities = 56/141 (39%), Positives = 73/141 (51%), Gaps = 10/141 (7%)
Query: 134 ERPRDGGAERQAGAAKKKTRTVFSRSQVYQLESTFDMKRYLSSSERACLASSLQLTETQV 193
E+ AER ++K R +FS++QVY+LE F +RYLS+ ER LAS L+LT TQV
Sbjct: 123 EKTEADNAERPRARRRRKPRVLFSQAQVYELERRFKQQRYLSAPERDQLASVLKLTSTQV 182
Query: 194 KTWFQNRRNKWKRQ---LSAELEAANMAHASAQTLVSMPLVFRDSSLLRVPVPRSLAFPA 250
K WFQNRR K KRQ + EL +++P++ RD P A A
Sbjct: 183 KIWFQNRRYKCKRQRQDQTLELVGLPPPPPPPARRIAVPVLVRDGK----PCLGDSAPYA 238
Query: 251 PLYYPGSN---LSALPLYNLY 268
P Y G N +A P Y Y
Sbjct: 239 PAYGVGLNPYGYNAYPAYPGY 259
>gi|28912912 NK6 transcription factor related, locus 2 [Homo
sapiens]
Length = 277
Score = 80.5 bits (197), Expect = 1e-15
Identities = 64/182 (35%), Positives = 84/182 (46%), Gaps = 31/182 (17%)
Query: 59 GWKAPACFCPDQHGPKEQGPKHHPPIPFPCLGTPKGSGGSGP-GGLERTPFLSPSHSDFK 117
G+KAPA G Q P P LG P G+ G G GGL R L+ S +
Sbjct: 39 GFKAPAL-----GGLGAQLPLGTPHGISDILGRPVGAAGGGLLGGLPRLNGLASSAGVYF 93
Query: 118 EEKERLLPAGSPSPGSERP----------------RD--------GGAERQAGAAKKKTR 153
+ G P P +E P RD G KK +R
Sbjct: 94 GPAAAVA-RGYPKPLAELPGRPPIFWPGVVQGAPWRDPRLAGPAPAGGVLDKDGKKKHSR 152
Query: 154 TVFSRSQVYQLESTFDMKRYLSSSERACLASSLQLTETQVKTWFQNRRNKWKRQLSAELE 213
FS Q++ LE TF+ +YL+ ERA LA SL +TE+QVK WFQNRR KW+++ +AE+
Sbjct: 153 PTFSGQQIFALEKTFEQTKYLAGPERARLAYSLGMTESQVKVWFQNRRTKWRKRHAAEMA 212
Query: 214 AA 215
+A
Sbjct: 213 SA 214
>gi|226437602 NK1 homeobox 2 [Homo sapiens]
Length = 310
Score = 80.1 bits (196), Expect = 2e-15
Identities = 49/101 (48%), Positives = 57/101 (56%), Gaps = 3/101 (2%)
Query: 125 PAGSP--SPGSERPRDGGAERQAGAAKKKTRTVFSRSQVYQLESTFDMKRYLSSSERACL 182
P SP SPGS RPR E A ++ RT F+ Q+ LE+ F RYLS ER L
Sbjct: 138 PVRSPPGSPGSPRPRRRRLEPNC-AKPRRARTAFTYEQLVALENKFRATRYLSVCERLNL 196
Query: 183 ASSLQLTETQVKTWFQNRRNKWKRQLSAELEAANMAHASAQ 223
A SL LTETQVK WFQNRR KWK+Q AA + + Q
Sbjct: 197 ALSLSLTETQVKIWFQNRRTKWKKQNPGADGAAQVGGGAPQ 237
>gi|239755439 PREDICTED: NK1 homeobox 2 [Homo sapiens]
Length = 332
Score = 80.1 bits (196), Expect = 2e-15
Identities = 49/101 (48%), Positives = 57/101 (56%), Gaps = 3/101 (2%)
Query: 125 PAGSP--SPGSERPRDGGAERQAGAAKKKTRTVFSRSQVYQLESTFDMKRYLSSSERACL 182
P SP SPGS RPR E A ++ RT F+ Q+ LE+ F RYLS ER L
Sbjct: 160 PVRSPPGSPGSPRPRRRRLEPNC-AKPRRARTAFTYEQLVALENKFRATRYLSVCERLNL 218
Query: 183 ASSLQLTETQVKTWFQNRRNKWKRQLSAELEAANMAHASAQ 223
A SL LTETQVK WFQNRR KWK+Q AA + + Q
Sbjct: 219 ALSLSLTETQVKIWFQNRRTKWKKQNPGADGAAQVGGGAPQ 259
>gi|239749920 PREDICTED: NK1 homeobox 2 [Homo sapiens]
Length = 332
Score = 80.1 bits (196), Expect = 2e-15
Identities = 49/101 (48%), Positives = 57/101 (56%), Gaps = 3/101 (2%)
Query: 125 PAGSP--SPGSERPRDGGAERQAGAAKKKTRTVFSRSQVYQLESTFDMKRYLSSSERACL 182
P SP SPGS RPR E A ++ RT F+ Q+ LE+ F RYLS ER L
Sbjct: 160 PVRSPPGSPGSPRPRRRRLEPNC-AKPRRARTAFTYEQLVALENKFRATRYLSVCERLNL 218
Query: 183 ASSLQLTETQVKTWFQNRRNKWKRQLSAELEAANMAHASAQ 223
A SL LTETQVK WFQNRR KWK+Q AA + + Q
Sbjct: 219 ALSLSLTETQVKIWFQNRRTKWKKQNPGADGAAQVGGGAPQ 259
>gi|239744223 PREDICTED: NK1 homeobox 2 [Homo sapiens]
Length = 332
Score = 80.1 bits (196), Expect = 2e-15
Identities = 49/101 (48%), Positives = 57/101 (56%), Gaps = 3/101 (2%)
Query: 125 PAGSP--SPGSERPRDGGAERQAGAAKKKTRTVFSRSQVYQLESTFDMKRYLSSSERACL 182
P SP SPGS RPR E A ++ RT F+ Q+ LE+ F RYLS ER L
Sbjct: 160 PVRSPPGSPGSPRPRRRRLEPNC-AKPRRARTAFTYEQLVALENKFRATRYLSVCERLNL 218
Query: 183 ASSLQLTETQVKTWFQNRRNKWKRQLSAELEAANMAHASAQ 223
A SL LTETQVK WFQNRR KWK+Q AA + + Q
Sbjct: 219 ALSLSLTETQVKIWFQNRRTKWKKQNPGADGAAQVGGGAPQ 259
>gi|24497526 homeobox B1 [Homo sapiens]
Length = 301
Score = 80.1 bits (196), Expect = 2e-15
Identities = 70/228 (30%), Positives = 106/228 (46%), Gaps = 34/228 (14%)
Query: 13 AAGGVSSFTIQSILGGG-PSEAPREPVGWPARK--RSLSVSSEEEEPDDGWKAPAC---F 66
+A V S+ + GGG S A ++ G+PA++ +L V P G+ AC +
Sbjct: 35 SAQAVDSYASEGRYGGGLSSPAFQQNSGYPAQQPPSTLGVPFPSSAPS-GYAPAACSPSY 93
Query: 67 CPDQHGPKEQ----GPKHHPPIPFPCLGTPK---GSGGSGPG---------GLERTPFLS 110
P Q+ P Q G HP LG G+GG+GPG G E+T +
Sbjct: 94 GPSQYYPLGQSEGDGGYFHPSSYGAQLGGLSDGYGAGGAGPGPYPPQHPPYGNEQTASFA 153
Query: 111 PSHSDF-KEEKERLLPAGSPSPGSER----------PRDGGAERQAGAAKKKTRTVFSRS 159
P+++D E+KE P+ +P + P+ + RT F+
Sbjct: 154 PAYADLLSEDKETPCPSEPNTPTARTFDWMKVKRNPPKTAKVSEPGLGSPSGLRTNFTTR 213
Query: 160 QVYQLESTFDMKRYLSSSERACLASSLQLTETQVKTWFQNRRNKWKRQ 207
Q+ +LE F +YLS + R +A++L+L ETQVK WFQNRR K K++
Sbjct: 214 QLTELEKEFHFNKYLSRARRVEIAATLELNETQVKIWFQNRRMKQKKR 261
>gi|19923352 NK3 homeobox 1 [Homo sapiens]
Length = 234
Score = 79.3 bits (194), Expect = 3e-15
Identities = 67/192 (34%), Positives = 88/192 (45%), Gaps = 21/192 (10%)
Query: 30 PSEAPREPVGWPARKRSLSVSSEEEEPDDGWKAPACFCPDQHGPKEQGPKHHPPIPFPCL 89
P EA E P + L+ ++ DG + G + + P P P
Sbjct: 9 PGEAKAEGAAPPTPSKPLTSFLIQDILRDG--------AQRQGGRTSSQRQRDPEPEP-- 58
Query: 90 GTPKGSGGSGPGG-----LERTPFLSPSHSDFKEEKERLLPAGSPSPGSERPRDGGAERQ 144
P+ GG G L P +P ++ E E GS SE G R
Sbjct: 59 -EPEPEGGRSRAGAQNDQLSTGPRAAPEEAETLAETEPERHLGSYLLDSENT-SGALPRL 116
Query: 145 AGAAK---KKTRTVFSRSQVYQLESTFDMKRYLSSSERACLASSLQLTETQVKTWFQNRR 201
K K++R FS +QV +LE F ++YLS+ ERA LA +L+LTETQVK WFQNRR
Sbjct: 117 PQTPKQPQKRSRAAFSHTQVIELERKFSHQKYLSAPERAHLAKNLKLTETQVKIWFQNRR 176
Query: 202 NKWKR-QLSAEL 212
K KR QLS+EL
Sbjct: 177 YKTKRKQLSSEL 188
>gi|111120318 NK6 transcription factor related, locus 1 [Homo
sapiens]
Length = 367
Score = 78.6 bits (192), Expect = 6e-15
Identities = 37/80 (46%), Positives = 50/80 (62%)
Query: 136 PRDGGAERQAGAAKKKTRTVFSRSQVYQLESTFDMKRYLSSSERACLASSLQLTETQVKT 195
P G +K TR FS Q++ LE TF+ +YL+ ERA LA SL +TE+QVK
Sbjct: 223 PHQGSILLDKDGKRKHTRPTFSGQQIFALEKTFEQTKYLAGPERARLAYSLGMTESQVKV 282
Query: 196 WFQNRRNKWKRQLSAELEAA 215
WFQNRR KW+++ +AE+ A
Sbjct: 283 WFQNRRTKWRKKHAAEMATA 302
>gi|4505401 NK2 transcription factor related, locus 2 [Homo sapiens]
Length = 273
Score = 78.2 bits (191), Expect = 7e-15
Identities = 62/195 (31%), Positives = 89/195 (45%), Gaps = 35/195 (17%)
Query: 69 DQHGPKEQGPKHHPPIPFPCLGTPKGSGGSGPGGLE-------RTPFLSPSHSDFKE--- 118
D+ G +GP+ P P K +G G G L+ + PF S + +
Sbjct: 23 DEEGSVAEGPEEENEGPEPA----KRAGPLGQGALDAVQSLPLKNPFYDSSDNPYTRWLA 78
Query: 119 EKERL------LPAG---------SPSPGSERPRDGGAERQAGAA----KKKTRTVFSRS 159
E L L AG SP P ++ D E G K+K R +FS++
Sbjct: 79 STEGLQYSLHGLAAGAPPQDSSSKSPEPSADESPDNDKETPGGGGDAGKKRKRRVLFSKA 138
Query: 160 QVYQLESTFDMKRYLSSSERACLASSLQLTETQVKTWFQNRRNKWKRQLSAELEAANMAH 219
Q Y+LE F +RYLS+ ER LAS ++LT TQVK WFQN R K KR + + +
Sbjct: 139 QTYELERRFRQQRYLSAPEREHLASLIRLTPTQVKIWFQNHRYKMKRARAE--KGMEVTP 196
Query: 220 ASAQTLVSMPLVFRD 234
+ V++P++ RD
Sbjct: 197 LPSPRRVAVPVLVRD 211
>gi|27886557 msh homeobox 2 [Homo sapiens]
Length = 267
Score = 77.8 bits (190), Expect = 9e-15
Identities = 56/124 (45%), Positives = 68/124 (54%), Gaps = 5/124 (4%)
Query: 150 KKTRTVFSRSQVYQLESTFDMKRYLSSSERACLASSLQLTETQVKTWFQNRRNKWKRQLS 209
+K RT F+ SQ+ LE F K+YLS +ERA +SSL LTETQVK WFQNRR K KR
Sbjct: 143 RKPRTPFTTSQLLALERKFRQKQYLSIAERAEFSSSLNLTETQVKIWFQNRRAKAKRLQE 202
Query: 210 AELEAANMAHASAQTLVSMPLVFRDSSLLRVPVPRSLAFP---APLYYPGSNLSALPL-Y 265
AELE MA A S L F SS L+ ++P L P L A P+ Y
Sbjct: 203 AELEKLKMA-AKPMLPSSFSLPFPISSPLQAASIYGASYPFHRPVLPIPPVGLYATPVGY 261
Query: 266 NLYN 269
+Y+
Sbjct: 262 GMYH 265
>gi|239748344 PREDICTED: NK1 homeobox 1 [Homo sapiens]
Length = 653
Score = 77.0 bits (188), Expect = 2e-14
Identities = 50/138 (36%), Positives = 67/138 (48%), Gaps = 23/138 (16%)
Query: 73 PKEQGPKHHPPIP---FPCLGTPKGSGGSGPGGLERTPFLSPSHSDFKEEKERLLPAGSP 129
P+ + PP P P P G G + PGG TP G+
Sbjct: 38 PEPPSTRQRPPGPRENSPVAPGPPG-GAAAPGGAGTTP------------------QGTA 78
Query: 130 SPGSERPRDGGAERQAGAAKKKTRTVFSRSQVYQLESTFDMKRYLSSSERACLASSLQLT 189
+ + + G++ ++G ++ RT F+ Q+ LE+ F RYLS ER LA SL LT
Sbjct: 79 TAAKPKRKRTGSDSKSGKPRR-ARTAFTYEQLVALENKFKATRYLSVCERLNLALSLSLT 137
Query: 190 ETQVKTWFQNRRNKWKRQ 207
ETQVK WFQNRR KWK+Q
Sbjct: 138 ETQVKIWFQNRRTKWKKQ 155
>gi|147901462 brain specific homeobox [Homo sapiens]
Length = 233
Score = 77.0 bits (188), Expect = 2e-14
Identities = 53/152 (34%), Positives = 68/152 (44%), Gaps = 50/152 (32%)
Query: 63 PACFCPDQHGPKEQGPKHHP------PIPFPCLGTPKGSGGSGPGGLERTPFLSPSHSDF 116
P P H P +G HHP +P P L F P H++
Sbjct: 62 PTLLAPHAHHPLHKGDHHHPYFLTTSGMPVPAL------------------FPHPQHAEL 103
Query: 117 KEEKERLLPAGSPSPGSERPRDGGAERQAGAAKKKTRTVFSRSQVYQLESTFDMKRYLSS 176
PG ++K RTVFS SQ+ LE F+++RYLS+
Sbjct: 104 --------------PGKH------------CRRRKARTVFSDSQLSGLEKRFEIQRYLST 137
Query: 177 SERACLASSLQLTETQVKTWFQNRRNKWKRQL 208
ER LA++L L+ETQVKTWFQNRR K K+QL
Sbjct: 138 PERVELATALSLSETQVKTWFQNRRMKHKKQL 169
>gi|84105335 mesenchyme homeobox 2 [Homo sapiens]
Length = 304
Score = 76.6 bits (187), Expect = 2e-14
Identities = 52/166 (31%), Positives = 73/166 (43%), Gaps = 18/166 (10%)
Query: 56 PDDGWKAPACFCPDQHGPKEQGPKHHPPIPFPCLGTPKGSGGSGPGGLERTP------FL 109
P + C PD GP E G PP+ G S P G P L
Sbjct: 100 PPSAARHSLCLQPDSGGPPELGSS--PPV---LCSNSSSLGSSTPTGAACAPGDYGRQAL 154
Query: 110 SPSHSDFKEEKERLLPAGSPSPGSERPRDGGAERQAGAAKKKTRTVFSRSQVYQLESTFD 169
SP+ ++ + G S ++G + + + +K RT F++ Q+ +LE+ F
Sbjct: 155 SPAEAEKRS-------GGKRKSDSSDSQEGNYKSEVNSKPRKERTAFTKEQIRELEAEFA 207
Query: 170 MKRYLSSSERACLASSLQLTETQVKTWFQNRRNKWKRQLSAELEAA 215
YL+ R +A +L LTE QVK WFQNRR KWKR + AA
Sbjct: 208 HHNYLTRLRRYEIAVNLDLTERQVKVWFQNRRMKWKRVKGGQQGAA 253
>gi|239742243 PREDICTED: HPX-153 homeobox [Homo sapiens]
Length = 411
Score = 76.6 bits (187), Expect = 2e-14
Identities = 48/131 (36%), Positives = 66/131 (50%), Gaps = 24/131 (18%)
Query: 77 GPKHHPPIPFPCLGTPKGSGGSGPGGLERTPFLSPSHSDFKEEKERLLPAGSPSPGSERP 136
GP+ + P+ G P G + PGG TP G+ + +
Sbjct: 211 GPRENSPV---AQGPP--GGAAAPGGAGTTP------------------QGTATAAKPKR 247
Query: 137 RDGGAERQAGAAKKKTRTVFSRSQVYQLESTFDMKRYLSSSERACLASSLQLTETQVKTW 196
+ G++ ++G ++ RT F+ Q+ LE+ F RYLS ER LA SL LTETQVK W
Sbjct: 248 KRTGSDSKSGKPRR-ARTAFTYEQLVALENKFKATRYLSVCERLNLALSLSLTETQVKIW 306
Query: 197 FQNRRNKWKRQ 207
FQNRR KWK+Q
Sbjct: 307 FQNRRTKWKKQ 317
>gi|239753784 PREDICTED: NK1 homeobox 1 [Homo sapiens]
Length = 814
Score = 76.3 bits (186), Expect = 3e-14
Identities = 48/131 (36%), Positives = 66/131 (50%), Gaps = 24/131 (18%)
Query: 77 GPKHHPPIPFPCLGTPKGSGGSGPGGLERTPFLSPSHSDFKEEKERLLPAGSPSPGSERP 136
GP+ + P+ G P G + PGG TP G+ + +
Sbjct: 614 GPRENSPV---APGPP--GGAAAPGGAGTTP------------------QGTATAAKPKR 650
Query: 137 RDGGAERQAGAAKKKTRTVFSRSQVYQLESTFDMKRYLSSSERACLASSLQLTETQVKTW 196
+ G++ ++G ++ RT F+ Q+ LE+ F RYLS ER LA SL LTETQVK W
Sbjct: 651 KRTGSDSKSGKPRR-ARTAFTYEQLVALENKFKATRYLSVCERLNLALSLSLTETQVKIW 709
Query: 197 FQNRRNKWKRQ 207
FQNRR KWK+Q
Sbjct: 710 FQNRRTKWKKQ 720
>gi|157426823 NK2 homeobox 4 [Homo sapiens]
Length = 354
Score = 72.8 bits (177), Expect = 3e-13
Identities = 36/67 (53%), Positives = 46/67 (68%)
Query: 141 AERQAGAAKKKTRTVFSRSQVYQLESTFDMKRYLSSSERACLASSLQLTETQVKTWFQNR 200
A A A ++K R +FS++QVY+LE F ++YLS+ ER LAS + LT TQVK WFQN
Sbjct: 181 AAAAAAAPRRKRRVLFSQAQVYELERRFKQQKYLSAPEREHLASMIHLTPTQVKIWFQNH 240
Query: 201 RNKWKRQ 207
R K KRQ
Sbjct: 241 RYKMKRQ 247
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.312 0.131 0.399
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 13,419,737
Number of Sequences: 37866
Number of extensions: 839718
Number of successful extensions: 3897
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 302
Number of HSP's successfully gapped in prelim test: 236
Number of HSP's that attempted gapping in prelim test: 3346
Number of HSP's gapped (non-prelim): 797
length of query: 273
length of database: 18,247,518
effective HSP length: 101
effective length of query: 172
effective length of database: 14,423,052
effective search space: 2480764944
effective search space used: 2480764944
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.