BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|7019335 hypothetical protein LOC745 isoform 1 [Homo sapiens] (1111 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|7019335 hypothetical protein LOC745 isoform 1 [Homo sapiens] 2291 0.0 gi|188528652 hypothetical protein LOC745 isoform 2 [Homo sapiens] 2253 0.0 gi|239750374 PREDICTED: chromosome 12 open reading frame 28 [Hom... 543 e-154 gi|169204180 PREDICTED: hypothetical protein LOC196446 [Homo sap... 543 e-154 gi|169204830 PREDICTED: hypothetical protein LOC196446 [Homo sap... 542 e-154 gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 75 3e-13 gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens] 66 2e-10 gi|41349482 proline-rich protein BstNI subfamily 1 isoform 1 pre... 65 3e-10 gi|42544130 splicing factor 1 isoform 1 [Homo sapiens] 65 5e-10 gi|116284398 WAS/WASL interacting protein family, member 1 [Homo... 64 6e-10 gi|38373695 WAS/WASL interacting protein family, member 1 [Homo ... 64 6e-10 gi|146134388 YLP motif containing 1 [Homo sapiens] 64 1e-09 gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi... 62 3e-09 gi|48255900 SWI/SNF-related matrix-associated actin-dependent re... 61 5e-09 gi|48255898 SWI/SNF-related matrix-associated actin-dependent re... 61 5e-09 gi|160707881 formin 2 [Homo sapiens] 61 7e-09 gi|117306167 proline-rich protein BstNI subfamily 3 precursor [H... 61 7e-09 gi|51702526 Wiskott-Aldrich syndrome gene-like protein [Homo sap... 60 9e-09 gi|19718731 bromodomain-containing protein 4 isoform long [Homo ... 60 9e-09 gi|42544125 splicing factor 1 isoform 2 [Homo sapiens] 59 2e-08 gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 59 3e-08 gi|5032069 splicing factor 3b, subunit 4 [Homo sapiens] 59 3e-08 gi|112382226 atrophin-1 like protein isoform b [Homo sapiens] 59 3e-08 gi|112382224 atrophin-1 like protein isoform a [Homo sapiens] 59 3e-08 gi|112382216 atrophin-1 like protein isoform a [Homo sapiens] 59 3e-08 gi|24308073 protein tyrosine phosphatase, non-receptor type 23 [... 58 4e-08 gi|21237805 SWI/SNF-related matrix-associated actin-dependent re... 58 4e-08 gi|18959210 WIRE protein [Homo sapiens] 58 4e-08 gi|153792074 proline rich 12 [Homo sapiens] 58 6e-08 gi|55750053 atrophin-1 [Homo sapiens] 57 7e-08 >gi|7019335 hypothetical protein LOC745 isoform 1 [Homo sapiens] Length = 1111 Score = 2291 bits (5936), Expect = 0.0 Identities = 1111/1111 (100%), Positives = 1111/1111 (100%) Query: 1 MHWLPAGHDINGALEPSNIDTSILEEYISKEDASDLCFPDISAPASSASYSHGQPAMPGS 60 MHWLPAGHDINGALEPSNIDTSILEEYISKEDASDLCFPDISAPASSASYSHGQPAMPGS Sbjct: 1 MHWLPAGHDINGALEPSNIDTSILEEYISKEDASDLCFPDISAPASSASYSHGQPAMPGS 60 Query: 61 SGVHHLSPPGGGPSPGRHGPLPPPGYGTPLNCNNNNGMGAAPKPFPGGTGPPIKAEPKAP 120 SGVHHLSPPGGGPSPGRHGPLPPPGYGTPLNCNNNNGMGAAPKPFPGGTGPPIKAEPKAP Sbjct: 61 SGVHHLSPPGGGPSPGRHGPLPPPGYGTPLNCNNNNGMGAAPKPFPGGTGPPIKAEPKAP 120 Query: 121 YAPGTLPDSPPDSGSEAYSPQQVNEPHLLRTITPETLCHVGVPSRLEHPPPPPAHLPGPP 180 YAPGTLPDSPPDSGSEAYSPQQVNEPHLLRTITPETLCHVGVPSRLEHPPPPPAHLPGPP Sbjct: 121 YAPGTLPDSPPDSGSEAYSPQQVNEPHLLRTITPETLCHVGVPSRLEHPPPPPAHLPGPP 180 Query: 181 PPPPPPPHYPVLQRDLYMKAEPPIPHYAAMGQGLVPTDLHHTQQSQMLHQLLQQHGAELP 240 PPPPPPPHYPVLQRDLYMKAEPPIPHYAAMGQGLVPTDLHHTQQSQMLHQLLQQHGAELP Sbjct: 181 PPPPPPPHYPVLQRDLYMKAEPPIPHYAAMGQGLVPTDLHHTQQSQMLHQLLQQHGAELP 240 Query: 241 THPSKKRKHSESPPSTLNAQMLNGMIKQEPGTVTALPLHPTRAPSPPWPPQGPLSPGPGS 300 THPSKKRKHSESPPSTLNAQMLNGMIKQEPGTVTALPLHPTRAPSPPWPPQGPLSPGPGS Sbjct: 241 THPSKKRKHSESPPSTLNAQMLNGMIKQEPGTVTALPLHPTRAPSPPWPPQGPLSPGPGS 300 Query: 301 LPLSIARVQTPPWHPPGAPSPGLLQDSDSLSGSYLDPNYQSIKWQPHQQNKWATLYDANY 360 LPLSIARVQTPPWHPPGAPSPGLLQDSDSLSGSYLDPNYQSIKWQPHQQNKWATLYDANY Sbjct: 301 LPLSIARVQTPPWHPPGAPSPGLLQDSDSLSGSYLDPNYQSIKWQPHQQNKWATLYDANY 360 Query: 361 KELPMLTYRVDADKGFNFSVGDDAFVCQKKNHFQVTVYIGMLGEPKYVKTPEGLKPLDCF 420 KELPMLTYRVDADKGFNFSVGDDAFVCQKKNHFQVTVYIGMLGEPKYVKTPEGLKPLDCF Sbjct: 361 KELPMLTYRVDADKGFNFSVGDDAFVCQKKNHFQVTVYIGMLGEPKYVKTPEGLKPLDCF 420 Query: 421 YLKLHGVKLEALNQSINIEQSQSDRSKRPFNPVTVNLPPEQVTKVTVGRLHFSETTANNM 480 YLKLHGVKLEALNQSINIEQSQSDRSKRPFNPVTVNLPPEQVTKVTVGRLHFSETTANNM Sbjct: 421 YLKLHGVKLEALNQSINIEQSQSDRSKRPFNPVTVNLPPEQVTKVTVGRLHFSETTANNM 480 Query: 481 RKKGKPNPDQRYFMLVVALQAHAQNQNYTLAAQISERIIVRASNPGQFESDSDVLWQRAQ 540 RKKGKPNPDQRYFMLVVALQAHAQNQNYTLAAQISERIIVRASNPGQFESDSDVLWQRAQ Sbjct: 481 RKKGKPNPDQRYFMLVVALQAHAQNQNYTLAAQISERIIVRASNPGQFESDSDVLWQRAQ 540 Query: 541 VPDTVFHHGRVGINTDRPDEALVVHGNVKVMGSLMHPSDLRAKEHVQEVDTTEQLKRISR 600 VPDTVFHHGRVGINTDRPDEALVVHGNVKVMGSLMHPSDLRAKEHVQEVDTTEQLKRISR Sbjct: 541 VPDTVFHHGRVGINTDRPDEALVVHGNVKVMGSLMHPSDLRAKEHVQEVDTTEQLKRISR 600 Query: 601 MRLVHYRYKPEFAASAGIEATAPETGVIAQEVKEILPEAVKDTGDMVFANGKTIENFLVV 660 MRLVHYRYKPEFAASAGIEATAPETGVIAQEVKEILPEAVKDTGDMVFANGKTIENFLVV Sbjct: 601 MRLVHYRYKPEFAASAGIEATAPETGVIAQEVKEILPEAVKDTGDMVFANGKTIENFLVV 660 Query: 661 NKERIFMENVGAVKELCKLTDNLETRIDELERWSHKLAKLRRLDSLKSTGSSGAFSHAGS 720 NKERIFMENVGAVKELCKLTDNLETRIDELERWSHKLAKLRRLDSLKSTGSSGAFSHAGS Sbjct: 661 NKERIFMENVGAVKELCKLTDNLETRIDELERWSHKLAKLRRLDSLKSTGSSGAFSHAGS 720 Query: 721 QFSRAGSVPHKKRPPKVASKSSSVVPDQACISQRFLQGTIIALVVVMAFSVVSMSTLYVL 780 QFSRAGSVPHKKRPPKVASKSSSVVPDQACISQRFLQGTIIALVVVMAFSVVSMSTLYVL Sbjct: 721 QFSRAGSVPHKKRPPKVASKSSSVVPDQACISQRFLQGTIIALVVVMAFSVVSMSTLYVL 780 Query: 781 SLRTEEDLVDTDGRSSQSFGTTQLRQSPLTTGLPGIQPSLLLVTTSLTSSAPGSAVRTLD 840 SLRTEEDLVDTDGRSSQSFGTTQLRQSPLTTGLPGIQPSLLLVTTSLTSSAPGSAVRTLD Sbjct: 781 SLRTEEDLVDTDGRSSQSFGTTQLRQSPLTTGLPGIQPSLLLVTTSLTSSAPGSAVRTLD 840 Query: 841 MCSSHPCPVICCSSPTTNPTTGPSLGPSFNPGHVLSPSPSPSTNRSGPSQMALLPVTNIR 900 MCSSHPCPVICCSSPTTNPTTGPSLGPSFNPGHVLSPSPSPSTNRSGPSQMALLPVTNIR Sbjct: 841 MCSSHPCPVICCSSPTTNPTTGPSLGPSFNPGHVLSPSPSPSTNRSGPSQMALLPVTNIR 900 Query: 901 AKSWGLSVNGIGHSKHHKSLEPLASPAVPFPGGQGKAKNSPSLGFHGRARRGALQSSVGP 960 AKSWGLSVNGIGHSKHHKSLEPLASPAVPFPGGQGKAKNSPSLGFHGRARRGALQSSVGP Sbjct: 901 AKSWGLSVNGIGHSKHHKSLEPLASPAVPFPGGQGKAKNSPSLGFHGRARRGALQSSVGP 960 Query: 961 AEPTWAQGQSEPVPSLTSIQVLENSMSITSQYCAPGDACRPGNFTYHIPVSSGTPLHLSL 1020 AEPTWAQGQSEPVPSLTSIQVLENSMSITSQYCAPGDACRPGNFTYHIPVSSGTPLHLSL Sbjct: 961 AEPTWAQGQSEPVPSLTSIQVLENSMSITSQYCAPGDACRPGNFTYHIPVSSGTPLHLSL 1020 Query: 1021 TLQMNSSSPVSVVLCSLRSKEEPCEEGSLPQSLHTHQDTQGTSHRWPITILSFREFTYHF 1080 TLQMNSSSPVSVVLCSLRSKEEPCEEGSLPQSLHTHQDTQGTSHRWPITILSFREFTYHF Sbjct: 1021 TLQMNSSSPVSVVLCSLRSKEEPCEEGSLPQSLHTHQDTQGTSHRWPITILSFREFTYHF 1080 Query: 1081 RVALLGQANCSSEALAQPATDYHFHFYRLCD 1111 RVALLGQANCSSEALAQPATDYHFHFYRLCD Sbjct: 1081 RVALLGQANCSSEALAQPATDYHFHFYRLCD 1111 >gi|188528652 hypothetical protein LOC745 isoform 2 [Homo sapiens] Length = 1151 Score = 2253 bits (5838), Expect = 0.0 Identities = 1104/1136 (97%), Positives = 1104/1136 (97%), Gaps = 31/1136 (2%) Query: 7 GHDINGALEPSNIDTSILEEYISKEDASDLCFPDISAPASSASYSHGQPAMPGSSGVHHL 66 GHDINGALEPSNIDTSILEEYISKEDASDLCFPDISAPASSASYSHGQPAMPGSSGVHHL Sbjct: 16 GHDINGALEPSNIDTSILEEYISKEDASDLCFPDISAPASSASYSHGQPAMPGSSGVHHL 75 Query: 67 SPPGGGPSPGRHGPLPPPGYGTPLNCNNNNGMGAAPKPFPGGTGPPIKAEPKAPYAPGTL 126 SPPGGGPSPGRHGPLPPPGYGTPLNCNNNNGMGAAPKPFPGGTGPPIKAEPKAPYAPGTL Sbjct: 76 SPPGGGPSPGRHGPLPPPGYGTPLNCNNNNGMGAAPKPFPGGTGPPIKAEPKAPYAPGTL 135 Query: 127 PDSPPDSGSEAYSPQQVNEPHLLRTITPETLCHVGVPSRLEHPPPPPAHLPGPPPPPPPP 186 PDSPPDSGSEAYSPQQVNEPHLLRTITPETLCHVGVPSRLEHPPPPPAHLPGPPPPPPPP Sbjct: 136 PDSPPDSGSEAYSPQQVNEPHLLRTITPETLCHVGVPSRLEHPPPPPAHLPGPPPPPPPP 195 Query: 187 PHYPVLQRDLYMKAEPPIPHYAAMGQGLVPTDLHHTQQSQMLHQLLQQHGAELPTHPSKK 246 PHYPVLQRDLYMKAEPPIPHYAAMGQGLVPTDLHHTQQSQMLHQLLQQHGAELPTHPSKK Sbjct: 196 PHYPVLQRDLYMKAEPPIPHYAAMGQGLVPTDLHHTQQSQMLHQLLQQHGAELPTHPSKK 255 Query: 247 RKHSESPPSTLNAQMLNGMIKQEPGTVTALPLHPTRAPSPPWPPQGPLSPGPGSLPLSIA 306 RKHSESPPSTLNAQMLNGMIKQEPGTVTALPLHPTRAPSPPWPPQGPLSPGPGSLPLSIA Sbjct: 256 RKHSESPPSTLNAQMLNGMIKQEPGTVTALPLHPTRAPSPPWPPQGPLSPGPGSLPLSIA 315 Query: 307 RVQTPPWHPPGAPSPGLLQDSDSLSGSYLDPNYQSIKWQPHQQNKWATLYDANYKELPML 366 RVQTPPWHPPGAPSPGLLQDSDSLSGSYLDPNYQSIKWQPHQQNKWATLYDANYKELPML Sbjct: 316 RVQTPPWHPPGAPSPGLLQDSDSLSGSYLDPNYQSIKWQPHQQNKWATLYDANYKELPML 375 Query: 367 TYRVDADKGFNFSVGDDAFVCQKKNHFQVTVYIGMLGEPKYVKTPEGLKPLDCFYLKLHG 426 TYRVDADKGFNFSVGDDAFVCQKKNHFQVTVYIGMLGEPKYVKTPEGLKPLDCFYLKLHG Sbjct: 376 TYRVDADKGFNFSVGDDAFVCQKKNHFQVTVYIGMLGEPKYVKTPEGLKPLDCFYLKLHG 435 Query: 427 VKLEALNQSINIEQSQSDRSKRPFNPVTVNLPPEQVTKVTVGRLHFSETTANNMRKKGKP 486 VKLEALNQSINIEQSQSDRSKRPFNPVTVNLPPEQVTKVTVGRLHFSETTANNMRKKGKP Sbjct: 436 VKLEALNQSINIEQSQSDRSKRPFNPVTVNLPPEQVTKVTVGRLHFSETTANNMRKKGKP 495 Query: 487 NPDQRYFMLVVALQAHAQNQNYTLAAQISERIIVRASNPGQFESDSDVLWQRAQVPDTVF 546 NPDQRYFMLVVALQAHAQNQNYTLAAQISERIIVRASNPGQFESDSDVLWQRAQVPDTVF Sbjct: 496 NPDQRYFMLVVALQAHAQNQNYTLAAQISERIIVRASNPGQFESDSDVLWQRAQVPDTVF 555 Query: 547 HHGRVGINTDRPDEALVVHGNVKVMGSLMHPSDLRAKEHVQEVDTTEQLKRISRMRLVHY 606 HHGRVGINTDRPDEALVVHGNVKVMGSLMHPSDLRAKEHVQEVDTTEQLKRISRMRLVHY Sbjct: 556 HHGRVGINTDRPDEALVVHGNVKVMGSLMHPSDLRAKEHVQEVDTTEQLKRISRMRLVHY 615 Query: 607 RYKPEFAASAGIEATAPETGVIAQEVKEILPEAVKDTGDMVFANGKTIENFLVVNKERIF 666 RYKPEFAASAGIEATAPETGVIAQEVKEILPEAVKDTGDMVFANGKTIENFLVVNKERIF Sbjct: 616 RYKPEFAASAGIEATAPETGVIAQEVKEILPEAVKDTGDMVFANGKTIENFLVVNKERIF 675 Query: 667 MENVGAVKELCKLTDNLETRIDELERWSHKLAKLRRLDSLKSTGSSGAFSHAGSQFSRAG 726 MENVGAVKELCKLTDNLETRIDELERWSHKLAKLRRLDSLKSTGSSGAFSHAGSQFSRAG Sbjct: 676 MENVGAVKELCKLTDNLETRIDELERWSHKLAKLRRLDSLKSTGSSGAFSHAGSQFSRAG 735 Query: 727 SVPHKKRPPKVASKSSSVVPDQACISQRFLQGTIIALVVVMAFSVVSMSTLYVLSLRTEE 786 SVPHKKRPPKVASKSSSVVPDQACISQRFLQGTIIALVVVMAFSVVSMSTLYVLSLRTEE Sbjct: 736 SVPHKKRPPKVASKSSSVVPDQACISQRFLQGTIIALVVVMAFSVVSMSTLYVLSLRTEE 795 Query: 787 DLVDTDGR--------------------------SSQSFGTTQLRQSPLTTGLPGIQPSL 820 DLVDTDG SSQSFGTTQLRQSPLTTGLPGIQPSL Sbjct: 796 DLVDTDGSFAVSTSCLLALLRPQPPGGSEALCPWSSQSFGTTQLRQSPLTTGLPGIQPSL 855 Query: 821 LLVTTSLTSSAPGSAVRTLDMCSSHPCPVICCSSPTTNPTTGPSLGPSFNPGHVLSPSPS 880 LLVTTSLTSSAPGSAVRTLDMCSSHPCPVICCSSPTTNPTTGPSLGPSFNPGHVLSPSPS Sbjct: 856 LLVTTSLTSSAPGSAVRTLDMCSSHPCPVICCSSPTTNPTTGPSLGPSFNPGHVLSPSPS 915 Query: 881 PSTNRSGPSQMALLPVTNIRAKSWGLSVNGIGHSKHHKSLEPLASPAVPFPGGQGKAKNS 940 PSTNRSGPSQMALLPVTNIRAKSWGLSVNGIGHSKHHKSLEPLASPAVPFPGGQGKAKNS Sbjct: 916 PSTNRSGPSQMALLPVTNIRAKSWGLSVNGIGHSKHHKSLEPLASPAVPFPGGQGKAKNS 975 Query: 941 PSLGFHGRARRGALQSSVGPAEPTWAQGQS-----EPVPSLTSIQVLENSMSITSQYCAP 995 PSLGFHGRARRGALQSSVGPAEPTWAQGQS EPVPSLTSIQVLENSMSITSQYCAP Sbjct: 976 PSLGFHGRARRGALQSSVGPAEPTWAQGQSASLLAEPVPSLTSIQVLENSMSITSQYCAP 1035 Query: 996 GDACRPGNFTYHIPVSSGTPLHLSLTLQMNSSSPVSVVLCSLRSKEEPCEEGSLPQSLHT 1055 GDACRPGNFTYHIPVSSGTPLHLSLTLQMNSSSPVSVVLCSLRSKEEPCEEGSLPQSLHT Sbjct: 1036 GDACRPGNFTYHIPVSSGTPLHLSLTLQMNSSSPVSVVLCSLRSKEEPCEEGSLPQSLHT 1095 Query: 1056 HQDTQGTSHRWPITILSFREFTYHFRVALLGQANCSSEALAQPATDYHFHFYRLCD 1111 HQDTQGTSHRWPITILSFREFTYHFRVALLGQANCSSEALAQPATDYHFHFYRLCD Sbjct: 1096 HQDTQGTSHRWPITILSFREFTYHFRVALLGQANCSSEALAQPATDYHFHFYRLCD 1151 >gi|239750374 PREDICTED: chromosome 12 open reading frame 28 [Homo sapiens] Length = 972 Score = 543 bits (1399), Expect = e-154 Identities = 361/853 (42%), Positives = 470/853 (55%), Gaps = 108/853 (12%) Query: 11 NGALEPSNIDTSILEEYISKE---DASDLCFPDISAPASSASYSHGQPAMPGSSGVHHLS 67 NG LE +DTS+LEE++ + A PD P SAS S P + G+ Sbjct: 20 NGTLENPALDTSLLEEFLGNDFDLGALQRQLPD--TPPYSASDSCSPPQVKGACY----- 72 Query: 68 PPGGGPSPGRHGPLPPPGYGTPLNCNNNNGMGAAPKPFPGGTGPPIKAEPKAPYAPGTLP 127 P P+ GR P PF T P + + Sbjct: 73 -PTLRPTAGR-----------------------TPAPFLHPTAAPAMPPMHPLQSTSGMG 108 Query: 128 DSPPDSGSEAYSPQQVNEPHLLRTITPETLCHVGVPSRLEHPPPPPAHLPGPPPPPPPPP 187 DS G + N HL + H+G+ +P P H PG PP Sbjct: 109 DSCQIHGG--FHSCHSNASHLATPLDQSVSSHLGIGC--SYPQQPLCHSPGASLPPTKKR 164 Query: 188 HYPVLQRDLYMKAEPPIPHYAAMGQGLVPTDLHHTQQSQMLHQLLQQH--GAELPTHPSK 245 D E + GL P H ++ QLL + G+ L K Sbjct: 165 KCTQALED---SGECRVWACHCRPNGLFP----HVRK--WCQQLLAMYLAGSNLMEKNEK 215 Query: 246 KRKHSESPPSTLNAQMLNGMIKQEPGTVTALPLHPTRAPSPP--WPPQGPLSPGPGSLPL 303 R + P P H T + P WP + S Sbjct: 216 MRSAAHLLP----------------------PAHDTSLVTLPYTWPTHQLHAASLTSRSR 253 Query: 304 SIARVQTPPWHPPGAPSPGLLQDSDSLSGSYLDPNYQSIKWQPHQQNKWATLYDANYKEL 363 S + VQ P DS+ + D ++KWQP W +L +++Y++L Sbjct: 254 S-SEVQDP--------------DSEGQNRMPTDQCSPALKWQPCHSVPWHSLLNSHYEKL 298 Query: 364 PMLTYRVDADKGFNFSVGDDAFVCQKKNHFQVTVYIGMLGEPKYVKTPEGLKPLDCFYLK 423 P + YRV DKGFNFS D+AFVCQKKNHFQ+T++I + G PK+V+T GLKP++ FYLK Sbjct: 299 PDVGYRVVTDKGFNFSPADEAFVCQKKNHFQITIHIQVWGSPKFVETEMGLKPIEMFYLK 358 Query: 424 LHGVKLEALNQSINIEQSQSDRSKRPFNPVTVNLPPEQVTKVTVGRLHFSETTANNMRKK 483 + G K+EA NQ I IEQSQ+DRSK+ FNPV ++L +QVTKVT+GRLHFSETTANNMRKK Sbjct: 359 VFGTKVEATNQIIAIEQSQADRSKKIFNPVKIDLLADQVTKVTLGRLHFSETTANNMRKK 418 Query: 484 GKPNPDQRYFMLVVALQAHAQNQNYTLAAQISERIIVRASNPGQFESDSDVLWQRAQVPD 543 GKPNPDQRYFMLVV L A Q+Q Y L+A ISERIIVRASNPGQFE+DSD LWQR QVP+ Sbjct: 419 GKPNPDQRYFMLVVGLYAANQDQFYLLSAHISERIIVRASNPGQFENDSDALWQRGQVPE 478 Query: 544 TVFHHGRVGINTDRPDEALVVHGNVKVMGSLMHPSDLRAKEHVQEVDTTEQLKRISRMRL 603 ++ HGRVGINTD PDEALVV GN+KVMG++MHPSD RAK+++QEVDT EQLKRI++MR+ Sbjct: 479 SIVCHGRVGINTDAPDEALVVCGNMKVMGTIMHPSDSRAKQNIQEVDTNEQLKRIAQMRI 538 Query: 604 VHYRYKPEFAASAGIEATAPETGVIAQEVKEILPEAVKDTGDMVFANGKTIENFLVVNKE 663 V Y YKPEFA++ GI TA +TG+IAQEV+EILP AV++ GD+ NG+T+ENFL+V+K+ Sbjct: 539 VEYDYKPEFASAMGIN-TAHQTGMIAQEVQEILPRAVREVGDVTCGNGETLENFLMVDKD 597 Query: 664 RIFMENVGAVKELCKLTDNLETRIDELERWSHKLAKLRRLDSLKSTGSSGAFSHAGSQFS 723 +IFMENVGAVK+LCKLT+NLE RI+ELE W+ KLA+L+RL S KS+ S + S+ S Sbjct: 598 QIFMENVGAVKQLCKLTNNLEERIEELEIWNRKLARLKRLSSWKSSASEAS---TISKSS 654 Query: 724 RAGSVPHKKRPPKVASKSSSVV---PDQACISQRFLQGTIIALVVVMAFSVVSMSTLYVL 780 RA S +R V K++ V QAC + F Q +I L+ VMAF +++ LY+L Sbjct: 655 RAVSASSPRR--AVHKKNNKVYFSGKRQACPNWVF-QTLVITLIAVMAFCALTIVALYIL 711 Query: 781 SLRTEEDLVDTDGRSSQSFGTTQLRQSPLTTGLPGIQPSLLLVTTSLTSSAPGSAVRTLD 840 SL+ ++ V S+ T ++ L P+ LVTT + P + Sbjct: 712 SLKDQDRRVPNLPPSN----ITSSQEPALLPTASSSAPNTSLVTTPASLQVP-----EIT 762 Query: 841 MCSSHPC-PVICC 852 C PC CC Sbjct: 763 FCEILPCQETYCC 775 Score = 87.0 bits (214), Expect = 9e-17 Identities = 46/143 (32%), Positives = 74/143 (51%), Gaps = 7/143 (4%) Query: 975 SLTSIQVLENSMSITSQYCAPGDACRPGNFTYHIPVSSGTPLHLSLTLQMNSSSPVSVVL 1034 +++SIQ++E I QYC C GN+ Y+IPV+ TP ++ +L++N++ P+ V Sbjct: 829 TISSIQIMEIQQIIDHQYCIQSLQCGSGNYNYNIPVNKHTPTNVKFSLEINTTEPLIVFQ 888 Query: 1035 CSLRSKEEPCEEGSLPQSLHTHQD-----TQGTSHRWPITILSFREFTYHFRVALLGQAN 1089 C + L +H++ TQG H W + + F + +HFRVA A+ Sbjct: 889 CKFTLGNICFHSKRGTKGLESHREISQEMTQGYQHIWSLPVAPFSDSMFHFRVAAPDLAD 948 Query: 1090 CSSEALAQPA--TDYHFHFYRLC 1110 CS++ TDY F+FYR C Sbjct: 949 CSTDPYFAGIFFTDYFFYFYRRC 971 >gi|169204180 PREDICTED: hypothetical protein LOC196446 [Homo sapiens] Length = 972 Score = 543 bits (1399), Expect = e-154 Identities = 361/853 (42%), Positives = 470/853 (55%), Gaps = 108/853 (12%) Query: 11 NGALEPSNIDTSILEEYISKE---DASDLCFPDISAPASSASYSHGQPAMPGSSGVHHLS 67 NG LE +DTS+LEE++ + A PD P SAS S P + G+ Sbjct: 20 NGTLENPALDTSLLEEFLGNDFDLGALQRQLPD--TPPYSASDSCSPPQVKGACY----- 72 Query: 68 PPGGGPSPGRHGPLPPPGYGTPLNCNNNNGMGAAPKPFPGGTGPPIKAEPKAPYAPGTLP 127 P P+ GR P PF T P + + Sbjct: 73 -PTLRPTAGR-----------------------TPAPFLHPTAAPAMPPMHPLQSTSGMG 108 Query: 128 DSPPDSGSEAYSPQQVNEPHLLRTITPETLCHVGVPSRLEHPPPPPAHLPGPPPPPPPPP 187 DS G + N HL + H+G+ +P P H PG PP Sbjct: 109 DSCQIHGG--FHSCHSNASHLATPLDQSVSSHLGIGC--SYPQQPLCHSPGASLPPTKKR 164 Query: 188 HYPVLQRDLYMKAEPPIPHYAAMGQGLVPTDLHHTQQSQMLHQLLQQH--GAELPTHPSK 245 D E + GL P H ++ QLL + G+ L K Sbjct: 165 KCTQALED---SGECRVWACHCRPNGLFP----HVRK--WCQQLLAMYLAGSNLMEKNEK 215 Query: 246 KRKHSESPPSTLNAQMLNGMIKQEPGTVTALPLHPTRAPSPP--WPPQGPLSPGPGSLPL 303 R + P P H T + P WP + S Sbjct: 216 MRSATHLLP----------------------PAHDTSLVTLPYTWPTHQLHAASLTSRSR 253 Query: 304 SIARVQTPPWHPPGAPSPGLLQDSDSLSGSYLDPNYQSIKWQPHQQNKWATLYDANYKEL 363 S + VQ P DS+ + D ++KWQP W +L +++Y++L Sbjct: 254 S-SEVQDP--------------DSEGQNRMPTDQCSPALKWQPCHSVPWHSLLNSHYEKL 298 Query: 364 PMLTYRVDADKGFNFSVGDDAFVCQKKNHFQVTVYIGMLGEPKYVKTPEGLKPLDCFYLK 423 P + YRV DKGFNFS D+AFVCQKKNHFQ+T++I + G PK+V+T GLKP++ FYLK Sbjct: 299 PDVGYRVVTDKGFNFSPADEAFVCQKKNHFQITIHIQVWGSPKFVETEMGLKPIEMFYLK 358 Query: 424 LHGVKLEALNQSINIEQSQSDRSKRPFNPVTVNLPPEQVTKVTVGRLHFSETTANNMRKK 483 + G K+EA NQ I IEQSQ+DRSK+ FNPV ++L +QVTKVT+GRLHFSETTANNMRKK Sbjct: 359 VFGTKVEATNQIIAIEQSQADRSKKIFNPVKIDLLADQVTKVTLGRLHFSETTANNMRKK 418 Query: 484 GKPNPDQRYFMLVVALQAHAQNQNYTLAAQISERIIVRASNPGQFESDSDVLWQRAQVPD 543 GKPNPDQRYFMLVV L A Q+Q Y L+A ISERIIVRASNPGQFE+DSD LWQR QVP+ Sbjct: 419 GKPNPDQRYFMLVVGLYAANQDQFYLLSAHISERIIVRASNPGQFENDSDALWQRGQVPE 478 Query: 544 TVFHHGRVGINTDRPDEALVVHGNVKVMGSLMHPSDLRAKEHVQEVDTTEQLKRISRMRL 603 ++ HGRVGINTD PDEALVV GN+KVMG++MHPSD RAK+++QEVDT EQLKRI++MR+ Sbjct: 479 SIVCHGRVGINTDAPDEALVVCGNMKVMGTIMHPSDSRAKQNIQEVDTNEQLKRIAQMRI 538 Query: 604 VHYRYKPEFAASAGIEATAPETGVIAQEVKEILPEAVKDTGDMVFANGKTIENFLVVNKE 663 V Y YKPEFA++ GI TA +TG+IAQEV+EILP AV++ GD+ NG+T+ENFL+V+K+ Sbjct: 539 VEYDYKPEFASAMGIN-TAHQTGMIAQEVQEILPRAVREVGDVTCGNGETLENFLMVDKD 597 Query: 664 RIFMENVGAVKELCKLTDNLETRIDELERWSHKLAKLRRLDSLKSTGSSGAFSHAGSQFS 723 +IFMENVGAVK+LCKLT+NLE RI+ELE W+ KLA+L+RL S KS+ S + S+ S Sbjct: 598 QIFMENVGAVKQLCKLTNNLEERIEELEIWNRKLARLKRLSSWKSSASEAS---TISKSS 654 Query: 724 RAGSVPHKKRPPKVASKSSSVV---PDQACISQRFLQGTIIALVVVMAFSVVSMSTLYVL 780 RA S +R V K++ V QAC + F Q +I L+ VMAF +++ LY+L Sbjct: 655 RAVSASSPRR--AVHKKNNKVYFSGKRQACPNWVF-QTLVITLIAVMAFCALTIVALYIL 711 Query: 781 SLRTEEDLVDTDGRSSQSFGTTQLRQSPLTTGLPGIQPSLLLVTTSLTSSAPGSAVRTLD 840 SL+ ++ V S+ T ++ L P+ LVTT + P + Sbjct: 712 SLKDQDRRVPNLPPSN----ITSSQEPALLPTASSSAPNTSLVTTPASLQVP-----EIT 762 Query: 841 MCSSHPC-PVICC 852 C PC CC Sbjct: 763 FCEILPCQETYCC 775 Score = 87.0 bits (214), Expect = 9e-17 Identities = 46/143 (32%), Positives = 74/143 (51%), Gaps = 7/143 (4%) Query: 975 SLTSIQVLENSMSITSQYCAPGDACRPGNFTYHIPVSSGTPLHLSLTLQMNSSSPVSVVL 1034 +++SIQ++E I QYC C GN+ Y+IPV+ TP ++ +L++N++ P+ V Sbjct: 829 TISSIQIMEIQQIIDHQYCIQSLQCGSGNYNYNIPVNKHTPTNVKFSLEINTTEPLIVFQ 888 Query: 1035 CSLRSKEEPCEEGSLPQSLHTHQD-----TQGTSHRWPITILSFREFTYHFRVALLGQAN 1089 C + L +H++ TQG H W + + F + +HFRVA A+ Sbjct: 889 CKFTLGNICFHSKRGTKGLESHREISQEMTQGYQHIWSLPVAPFSDSMFHFRVAAPDLAD 948 Query: 1090 CSSEALAQPA--TDYHFHFYRLC 1110 CS++ TDY F+FYR C Sbjct: 949 CSTDPYFAGIFFTDYFFYFYRRC 971 >gi|169204830 PREDICTED: hypothetical protein LOC196446 [Homo sapiens] Length = 910 Score = 542 bits (1397), Expect = e-154 Identities = 338/741 (45%), Positives = 439/741 (59%), Gaps = 91/741 (12%) Query: 126 LPDSPPDSGSEAYSPQQVNEPHLLRTITPETLCHVGVPSRLEHPPPPPAHLPGPPPPPPP 185 LPD+PP S S++ SP QV + C+ + P P H P P Sbjct: 50 LPDTPPYSASDSCSPPQV-----------KGACYPTLRPTAGRTPAPFLH---PTAAPAM 95 Query: 186 PPHYPVLQRDLYMKAEPPIP---HYAAMGQGLVPTDLHHTQQSQM-------LHQLLQQH 235 PP +P LQ M I H + T L + S + L Sbjct: 96 PPMHP-LQSTSGMGDSCQIHGGFHSCHSNASHLATPLDQSVSSHLGIGCSYPQQPLCHSP 154 Query: 236 GAELPTHPSKKRKHSESPPSTLNAQMLNGMIKQEPGTVTALPLHPTRAPSPPWPPQGPLS 295 GA LP P+KKRK +++ + + V A P + S Q P S Sbjct: 155 GASLP--PTKKRKCTQALEDSGECR------------VWACHCRPMTSRSRSSEVQDPDS 200 Query: 296 PGPGSLPLSIARVQTPPWHPPGAPSPGLLQDSDSLSGSYLDPNYQSIKWQPHQQNKWATL 355 G +P Q P ++KWQP W +L Sbjct: 201 EGQNRMPTD----QCSP----------------------------ALKWQPCHSVPWHSL 228 Query: 356 YDANYKELPMLTYRVDADKGFNFSVGDDAFVCQKKNHFQVTVYIGMLGEPKYVKTPEGLK 415 +++Y++LP + YRV DKGFNFS D+AFVCQKKNHFQ+T++I + G PK+V+T GLK Sbjct: 229 LNSHYEKLPDVGYRVVTDKGFNFSPADEAFVCQKKNHFQITIHIQVWGSPKFVETEMGLK 288 Query: 416 PLDCFYLKLHGVKLEALNQSINIEQSQSDRSKRPFNPVTVNLPPEQVTKVTVGRLHFSET 475 P++ FYLK+ G K+EA NQ I IEQSQ+DRSK+ FNPV ++L +QVTKVT+GRLHFSET Sbjct: 289 PIEMFYLKVFGTKVEATNQIIAIEQSQADRSKKIFNPVKIDLLADQVTKVTLGRLHFSET 348 Query: 476 TANNMRKKGKPNPDQRYFMLVVALQAHAQNQNYTLAAQISERIIVRASNPGQFESDSDVL 535 TANNMRKKGKPNPDQRYFMLVV L A Q+Q Y L+A ISERIIVRASNPGQFE+DSD L Sbjct: 349 TANNMRKKGKPNPDQRYFMLVVGLYAANQDQFYLLSAHISERIIVRASNPGQFENDSDAL 408 Query: 536 WQRAQVPDTVFHHGRVGINTDRPDEALVVHGNVKVMGSLMHPSDLRAKEHVQEVDTTEQL 595 WQR QVP+++ HGRVGINTD PDEALVV GN+KVMG++MHPSD RAK+++QEVDT EQL Sbjct: 409 WQRGQVPESIVCHGRVGINTDAPDEALVVCGNMKVMGTIMHPSDSRAKQNIQEVDTNEQL 468 Query: 596 KRISRMRLVHYRYKPEFAASAGIEATAPETGVIAQEVKEILPEAVKDTGDMVFANGKTIE 655 KRI++MR+V Y YKPEFA++ GI TA +TG+IAQEV+EILP AV++ GD+ NG+T+E Sbjct: 469 KRIAQMRIVEYDYKPEFASAMGIN-TAHQTGMIAQEVQEILPRAVREVGDVTCGNGETLE 527 Query: 656 NFLVVNKERIFMENVGAVKELCKLTDNLETRIDELERWSHKLAKLRRLDSLKSTGSSGAF 715 NFL+V+K++IFMENVGAVK+LCKLT+NLE RI+ELE W+ KLA+L+RL S KS+ S + Sbjct: 528 NFLMVDKDQIFMENVGAVKQLCKLTNNLEERIEELEIWNRKLARLKRLSSWKSSASEAS- 586 Query: 716 SHAGSQFSRAGSVPHKKRPPKVASKSSSVV---PDQACISQRFLQGTIIALVVVMAFSVV 772 S+ SRA S +R V K++ V QAC + F Q +I L+ VMAF + Sbjct: 587 --TISKSSRAVSASSPRR--AVHKKNNKVYFSGKRQACPNWVF-QTLVITLIAVMAFCAL 641 Query: 773 SMSTLYVLSLRTEEDLVDTDGRSSQSFGTTQLRQSPLTTGLPGIQPSLLLVTTSLTSSAP 832 ++ LY+LSL+ ++ V S+ T ++ L P+ LVTT + P Sbjct: 642 TIVALYILSLKDQDRRVPNLPPSN----ITSSQEPALLPTASSSAPNTSLVTTPASLQVP 697 Query: 833 GSAVRTLDMCSSHPC-PVICC 852 + C PC CC Sbjct: 698 -----EITFCEILPCQETYCC 713 Score = 87.0 bits (214), Expect = 9e-17 Identities = 46/143 (32%), Positives = 74/143 (51%), Gaps = 7/143 (4%) Query: 975 SLTSIQVLENSMSITSQYCAPGDACRPGNFTYHIPVSSGTPLHLSLTLQMNSSSPVSVVL 1034 +++SIQ++E I QYC C GN+ Y+IPV+ TP ++ +L++N++ P+ V Sbjct: 767 TISSIQIMEIQQIIDHQYCIQSLQCGSGNYNYNIPVNKHTPTNVKFSLEINTTEPLIVFQ 826 Query: 1035 CSLRSKEEPCEEGSLPQSLHTHQD-----TQGTSHRWPITILSFREFTYHFRVALLGQAN 1089 C + L +H++ TQG H W + + F + +HFRVA A+ Sbjct: 827 CKFTLGNICFHSKRGTKGLESHREISQEMTQGYQHIWSLPVAPFSDSMFHFRVAAPDLAD 886 Query: 1090 CSSEALAQPA--TDYHFHFYRLC 1110 CS++ TDY F+FYR C Sbjct: 887 CSTDPYFAGIFFTDYFFYFYRRC 909 Score = 34.7 bits (78), Expect = 0.52 Identities = 47/179 (26%), Positives = 63/179 (35%), Gaps = 44/179 (24%) Query: 11 NGALEPSNIDTSILEEYISKE---DASDLCFPDISAPASSASYSHGQPAMPGSSGVHHLS 67 NG LE +DTS+LEE++ + A PD P SAS S P + G+ Sbjct: 20 NGTLENPALDTSLLEEFLGNDFDLGALQRQLPD--TPPYSASDSCSPPQVKGACYPTLRP 77 Query: 68 PPGGGPSPGRH---GPLPPPGYGTPLNCNNNNGMGAAPKPFPGGTGPPIKAEPKAPYAPG 124 G P+P H P PP + PL + +GMG Sbjct: 78 TAGRTPAPFLHPTAAPAMPPMH--PL--QSTSGMG------------------------- 108 Query: 125 TLPDSPPDSGSEAYSPQQVNEPHLLRTITPETLCHVGVPSRLEHPPPPPAHLPGPPPPP 183 DS G + N HL + H+G+ +P P H PG PP Sbjct: 109 ---DSCQIHG--GFHSCHSNASHLATPLDQSVSSHLGI--GCSYPQQPLCHSPGASLPP 160 >gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapiens] Length = 1124 Score = 75.1 bits (183), Expect = 3e-13 Identities = 87/359 (24%), Positives = 117/359 (32%), Gaps = 80/359 (22%) Query: 41 ISAPASSASYSHG------QPAMPGSSGVHHLSPPGGGPSPGRHGPLPPPGYGTPLNCNN 94 +S+PA S + G P+ P G+ L PP P P P +PL + Sbjct: 249 LSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPS 308 Query: 95 NNGMGAAPKPFPGGTGPPIKAE--------------PKAPYAPGTL------PDSPPDSG 134 +G A P P P P+ A P +P AP +L P +PP Sbjct: 309 PSGTKARPVPPPDNAATPLPATLPPSPPLATPLPLAPPSPSAPPSLQTLPSPPATPPSQA 368 Query: 135 SEAYSPQQVNEPHLLRTITPETLCHVGVPSRLEHPPPP---------------------- 172 + + + P L+TI P + H L+ PP P Sbjct: 369 PPSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQAPPSPLALSSLQATTSLGSPTLQATHS 428 Query: 173 ---------PAHLPGPPPPPPPPPHYPVLQRDLYMKAEPPIPHYAAMGQGLVPTDLHHTQ 223 A L P P PP P LQ L + A PP+ ++ + P T Sbjct: 429 FLTMSPRQTQASLTSPSRPASTPPDSPPLQAPLSLPASPPL--QTSLSPAVSPLSSPLTI 486 Query: 224 QSQMLHQLLQQHGAELP----------THPSKKRKHSESPPSTLNAQMLNGM-------- 265 L H + P T S ++PP++L L + Sbjct: 487 HPLQALSSLASHSPQAPLSSLIMPPLETQSSLAPPSLQTPPASLTTPPLENLPSLAPPPL 546 Query: 266 -IKQEPGTVTALPLHPTRAPSPPWPPQGPLSPGPGSLPLSIARVQTPPWHPPGAPSPGL 323 P T L P AP P P PL+ P P SIA PP PP SP L Sbjct: 547 QTASAPLTTPHLETPPCPAPCPLQAPPSPLTTPPPETPSSIA--TPPPQAPPALASPPL 603 Score = 60.1 bits (144), Expect = 1e-08 Identities = 74/292 (25%), Positives = 98/292 (33%), Gaps = 26/292 (8%) Query: 33 ASDLCFPDISAPASSASYSHGQPA----MPGSSGVHHLSPPGGGPSPGRHGPLPPPGYGT 88 +S L + A +S AS+S P MP L+PP PP T Sbjct: 481 SSPLTIHPLQALSSLASHSPQAPLSSLIMPPLETQSSLAPPSL--------QTPPASLTT 532 Query: 89 PLNCNNNNGMGAAPKPFPGGTGPPIKAEPKAPYAPGTLPDSPPDSGSEAYSPQQVNEPHL 148 P N AP P + P + P P P P S P+ P Sbjct: 533 P---PLENLPSLAPPPLQTASAPLTTPHLETPPCPAPCPLQAPPSPLTTPPPET---PSS 586 Query: 149 LRTITPETLCHVGVPSRLEHPPPPPAHLPGPPPPPPPPPHYPVLQRDLYMKAEPPIPHYA 208 + T P+ + P P PP + L PPP PP P LQ A PP+ A Sbjct: 587 IATPPPQAPPALASPPLQGLPSPPLSPLATPPPQAPPXLALPPLQAPPSPPASPPLSPLA 646 Query: 209 AMGQGLVPTDLHHTQQSQMLHQLLQQHGAELPTHPSKKRKHSESPPSTLNAQMLNGMIKQ 268 H Q+ A S S +PPS + ++ Sbjct: 647 TPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQV 706 Query: 269 EPGTVTALPLHPTRAPSPPWPPQGPLSPGPGSLPLSIARVQTPPWHPPGAPS 320 P + P+ P+ P P PP PL+ P +P S PP PP +PS Sbjct: 707 PPSPPASPPMSPSATPPPQAPP--PLAAPPLQVPPS------PPASPPMSPS 750 Score = 55.8 bits (133), Expect = 2e-07 Identities = 84/332 (25%), Positives = 110/332 (33%), Gaps = 65/332 (19%) Query: 36 LCFPDISAPASSAS------YSHGQPAMPGSSGVHHLSPP-GGGPSPGRHGPLPPPGYGT 88 L P + AP S + + P P + VH L P PSP P PP + Sbjct: 625 LALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPA--S 682 Query: 89 PLNCNNNNGMGAAPKPFPGGTGPPIKAEPKAPYAPGTLPDSPPDSGSE---AYSPQQVN- 144 P + AP P PP++ P P +P P + P + A P QV Sbjct: 683 PPVSPSATPPSQAP---PSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQVPP 739 Query: 145 EPHLLRTITPETLCHVGVPSRL-----EHPPPPPAHLPGPPPPPPPPPHYPVLQRDLYMK 199 P ++P VP L + PP PPA LP P PPP P L Sbjct: 740 SPPASPPMSPSATPPPRVPPLLAAPPLQVPPSPPASLPMSPLAKPPPQAPPAL------- 792 Query: 200 AEPP---IPHYAAMGQGLVPTDLHHTQQSQMLHQLLQQHGAELPTHPSKKRKHSESPPST 256 A PP +P A G P A LP P +PP Sbjct: 793 ATPPLQALPSPPASFPGQAPF----------------SPSASLPMSP------LATPPPQ 830 Query: 257 LNAQMLNGMIKQEPGTVTALPLHPTRAPSPPWPPQGPLSPGPGSLPLSIARVQTPPWHPP 316 + +++ P + L R P P P P L L++A P Sbjct: 831 APPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGP---RLTLALA---------P 878 Query: 317 GAPSPGLLQDSDSLSGSYLDPNYQSIKWQPHQ 348 G P P S +LSG L + S P + Sbjct: 879 GPPPPPSRSPSSTLSGPDLAGHSSSATSTPEE 910 Score = 36.2 bits (82), Expect = 0.18 Identities = 76/310 (24%), Positives = 99/310 (31%), Gaps = 57/310 (18%) Query: 42 SAPASSASYSHGQPAM-PGSSGVHHLSPPGGGPSPGRHGPLPPPGYGTPLNCNNNNGMGA 100 + P SA S PA P +SG +PP SPG P+ PG + Sbjct: 77 AGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPG---PVSSPGRAS-----------G 122 Query: 101 APKPFP-GGTGPPIKAEPKAPYAPGTLPDSPPDSGSEAYSPQQVNEPHLLRTITPETLCH 159 +P P G G I AE A G ++P S A + + + P TP Sbjct: 123 TTRPGPLGQKGLRISAEETV--ARGKATEAPKRSALSAGARRDTSGP------TP----- 169 Query: 160 VGVPS----RLEHPPPPPAHLPGPPP-----PPPPPPHYPVLQRDLYMKAEPP--IPHYA 208 G PS R LP P P PP P V + EP Sbjct: 170 -GTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRP 228 Query: 209 AMGQGLVPTDLHHTQQSQMLHQLLQQHGAEL------PTHPSKKR-------KHSESPPS 255 + G GL S + G P HPS+ + + + P Sbjct: 229 SAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPP 288 Query: 256 TLNAQMLNGMIKQEPGTVTALPLHPTRAPSPPWPPQGPLSPGPGSLPLSIARVQTPPWHP 315 +A G + P T P P PP P +P P +LP S P P Sbjct: 289 RKDAAPALGPLSSSP-LATPSPSGTKARPVPP--PDNAATPLPATLPPSPPLATPLPLAP 345 Query: 316 PGAPSPGLLQ 325 P +P LQ Sbjct: 346 PSPSAPPSLQ 355 Score = 34.3 bits (77), Expect = 0.67 Identities = 30/88 (34%), Positives = 36/88 (40%), Gaps = 8/88 (9%) Query: 801 TTQLRQSPLTTGLPGIQPSLLLVTTSLTSSAPGSAVRTLDMCSSHPCPVICCSSPTTNPT 860 + L SPL T P P L + S P S TL P P P T+ Sbjct: 816 SASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASP--TLQAPRRPPTP-----GPDTS-V 867 Query: 861 TGPSLGPSFNPGHVLSPSPSPSTNRSGP 888 +GP L + PG PS SPS+ SGP Sbjct: 868 SGPRLTLALAPGPPPPPSRSPSSTLSGP 895 Score = 32.3 bits (72), Expect = 2.6 Identities = 36/129 (27%), Positives = 49/129 (37%), Gaps = 29/129 (22%) Query: 29 SKEDASDLCFPDISAPASSASYSHGQPAM--PGSSGVHHLSPPGGG------PSPGRHGP 80 S+ +S L PD++ +SSA+ + + G G SPP P+ GP Sbjct: 885 SRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGP 944 Query: 81 LPPPGYGTPLNCNNNNGMGAAPKPFPGGTGP----------PIKAEPKAPYAPGTLP--D 128 PP + G AP P+P TGP + A APG L Sbjct: 945 APPLAF---------RGAPGAPLPWPPATGPGSADGLCTIYETEGPESATPAPGALDPGP 995 Query: 129 SPPDSGSEA 137 SP SG +A Sbjct: 996 SPGTSGGKA 1004 >gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens] Length = 416 Score = 65.9 bits (159), Expect = 2e-10 Identities = 85/322 (26%), Positives = 108/322 (33%), Gaps = 60/322 (18%) Query: 24 LEEYISKEDASDLCFPDIS-APASSASYSHGQPAMPGSSGVHHLSPPGGGPSPGRHGPLP 82 L E +S+E++ L + AP + G P+ PG PP GG P GP P Sbjct: 19 LNEDVSQEESPSLIAGNPQGAPPQGGNKPQGPPSPPGKP---QGPPPQGGNQP--QGPPP 73 Query: 83 PPGYGTPLNCNNNNGMGAAPKPFPGGTGPPIKAEPKAPYAPGTLPDSPPDSGSEAYSPQQ 142 PPG P G P +P+ P PG P PP G ++ SP+ Sbjct: 74 PPGK-------------------PQGPPPQGGNKPQGPPPPGK-PQGPPPQGDKSRSPRS 113 Query: 143 VNEPHLLRTITPETLCHVGVPSRLEHPPPPPAHLPGPPPPPPPPPHYPVLQRDLYMKAEP 202 P + + PPP + P PPPPP P P Q + P Sbjct: 114 P-------------------PGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPP 154 Query: 203 PIPHYAAMGQGLVPTDLHHTQQSQMLHQLLQ----QHGAELPTHPSKKRKHSESPPSTLN 258 P QG P + ++ S+ Q Q G + P K PP N Sbjct: 155 P----PGKPQGPPPQGDNKSRSSRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGN 210 Query: 259 AQMLNGMIKQEPGTVTALPLHPTRAPSPPWPPQGPLSPG---PGSLPLSIARVQTPPWH- 314 + G A SPP PQGP G P P + Q PP Sbjct: 211 KPQGPPPPGKPQGPPPQGDNKSQSARSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQG 270 Query: 315 ---PPGAPSPGLLQDSDSLSGS 333 P G P PG Q GS Sbjct: 271 GNKPQGPPPPGKPQGPPPQGGS 292 Score = 65.9 bits (159), Expect = 2e-10 Identities = 79/289 (27%), Positives = 98/289 (33%), Gaps = 53/289 (18%) Query: 44 PASSASYSHGQPAMPGSSGVHHLSPPGGGPSPGRHGPLPPPG--YGTPLNCNNNNGMGAA 101 P + G P PG PP GG P GP PPPG G P +N + + Sbjct: 122 PPQGGNQPQGPPPPPGKP---QGPPPQGGNKP--QGP-PPPGKPQGPPPQGDNKSRSSRS 175 Query: 102 PKPFPGGTGPPIKAEPKAPYAPGTLPDSPPDSGSEAYSPQQVNEPHLLRTITPE----TL 157 P P G P +P+ P P P PP G PQ P + P+ + Sbjct: 176 PPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGN--KPQGPPPPGKPQGPPPQGDNKSQ 233 Query: 158 CHVGVPSRLEHPPPPPAHLPGPPPPPPPPPHYPVLQRDLYMKAEPPIPHYAAMGQGLVPT 217 P + + PPP + P PPPPP P P Q + PP QG P Sbjct: 234 SARSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPP----PGKPQGPPP- 288 Query: 218 DLHHTQQSQMLHQLLQQHGAELPTHPSKKRKHSESPPSTLNAQMLNGMIKQEPGTVTALP 277 Q G++ + S K PP G Q P P Sbjct: 289 ----------------QGGSKSRSSRSPPGKPQGPPPQ-------GGNQPQGPPPPPGKP 325 Query: 278 LHP-------TRAPSPPWPPQGPLSPGPGSLPLSIARVQTPPWHPPGAP 319 P + P PP PQGP P GS S ++PP P G P Sbjct: 326 QGPPPQGGNKPQGPPPPGKPQGP-PPQGGSKSRS---ARSPPGKPQGPP 370 Score = 45.1 bits (105), Expect = 4e-04 Identities = 46/163 (28%), Positives = 55/163 (33%), Gaps = 44/163 (26%) Query: 44 PASSASYSHGQPAMPGSSGVHHLSPPGGGPSPGRHGPLPPPG--YGTPLNCNNNNGMGAA 101 P + G P PG PP GG P GP PPPG G P + + + Sbjct: 246 PPQGGNQPQGPPPPPGKP---QGPPPQGGNKP--QGP-PPPGKPQGPPPQGGSKSRSSRS 299 Query: 102 PKPFPGGTGPPIKAEPKAPYAPGTLPDSPPDSGSEAYSPQQVNEPHLLRTITPETLCHVG 161 P P G P +P+ P P P PP PQ N+P Sbjct: 300 PPGKPQGPPPQGGNQPQGPPPPPGKPQGPP--------PQGGNKPQ-----------GPP 340 Query: 162 VPSRLEHPPP-----------PPAHLPGPP------PPPPPPP 187 P + + PPP PP GPP P PPPP Sbjct: 341 PPGKPQGPPPQGGSKSRSARSPPGKPQGPPQQEGNNPQGPPPP 383 Score = 43.1 bits (100), Expect = 0.001 Identities = 44/155 (28%), Positives = 52/155 (33%), Gaps = 15/155 (9%) Query: 39 PDISAPASSASYSHGQPAMPGSSGVHHLSPPGGGPSPGRHGPLPPPGYGTPLNCNNNNGM 98 P P +P P G PP GG S R PP P N Sbjct: 258 PPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGG-SKSRSSRSPPGKPQGPPPQGGNQPQ 316 Query: 99 GAAPKPF-PGGTGPPIKAEPKAPYAPGTLPDSPPDSGSEAYS----PQQVNEPHLLRTIT 153 G P P P G P +P+ P PG PP GS++ S P + P Sbjct: 317 GPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGGSKSRSARSPPGKPQGPPQQEGNN 376 Query: 154 PETLCHVGVP----SRLEHPPPPPAHLPGPPPPPP 184 P+ G P + P PPA P PP PP Sbjct: 377 PQ-----GPPPPAGGNPQQPQAPPAGQPQGPPRPP 406 >gi|41349482 proline-rich protein BstNI subfamily 1 isoform 1 preproprotein [Homo sapiens] Length = 331 Score = 65.5 bits (158), Expect = 3e-10 Identities = 75/304 (24%), Positives = 102/304 (33%), Gaps = 60/304 (19%) Query: 24 LEEYISKEDASDLCFPDISAPA-SSASYSHGQPAMPGSSGVHHLSPPGGGPSPGRHGPLP 82 L E +S+E++ L + P+ + G P PG P G P G + P Sbjct: 19 LNEDVSQEESPSLIAGNPQGPSPQGGNKPQGPPPPPGK--------PQGPPPQGGNKPQG 70 Query: 83 PPGYGTPLNCNNNNGMGAAPKPFPGGT-GPPIKA--EPKAPYAPGTLPDSPP-DSGSEAY 138 PP G P +P+ PG GPP + +P+ P P P PP G+ Sbjct: 71 PPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNRPQ 130 Query: 139 SPQQVNEPHLLRTITPETLCHVGVPSRLEHPPPPPAHLPGPPPPPPPPPHYPVLQRDLYM 198 P +P ++ P + + PPP + P PPPPP P P Q Sbjct: 131 GPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGKKP 190 Query: 199 KAEPPIPHYAAMGQGLVPTDLHHTQQSQMLHQLLQQHGAELPTHPSKKRKHSESPPSTLN 258 + PP QG P K + S+SPP Sbjct: 191 QGPPP----PGKPQG--------------------------PPPQGDKSRSSQSPPGKPQ 220 Query: 259 AQMLNGMIKQEPGTVTALPLHPTRAPSPPWPPQGPLSPGPGSLPLSIARVQTPPWHPPGA 318 G + P P PP PQGP P G+ P + PP P G Sbjct: 221 GPPPQGGNQ------------PQGPPPPPGKPQGP-PPQGGNKP----QGPPPPGKPQGP 263 Query: 319 PSPG 322 P+ G Sbjct: 264 PAQG 267 Score = 40.0 bits (92), Expect = 0.012 Identities = 49/169 (28%), Positives = 58/169 (34%), Gaps = 37/169 (21%) Query: 44 PASSASYSHGQPAMPGSSGVHHLSPPGGG------PSPGR-HGPLP----------PPG- 85 P + G P PG PP GG P PG+ GP P PPG Sbjct: 162 PPQGGNQPQGPPPPPGKP---QGPPPQGGKKPQGPPPPGKPQGPPPQGDKSRSSQSPPGK 218 Query: 86 -YGTPLNCNNNNGMGAAPKPF-PGGTGPPIKAEPKAPYAPGTLPDSPPDSGSEAYS---- 139 G P N G P P P G P +P+ P PG P GS++ S Sbjct: 219 PQGPPPQ-GGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPAQGGSKSQSARSP 277 Query: 140 PQQVNEPHLLRTITPETLCHVGVP----SRLEHPPPPPAHLPGPPPPPP 184 P + P P+ G P + P PPA P PP PP Sbjct: 278 PGKPQGPPQQEGNNPQ-----GPPPPAGGNPQQPQAPPAGQPQGPPRPP 321 Score = 38.9 bits (89), Expect = 0.027 Identities = 40/124 (32%), Positives = 44/124 (35%), Gaps = 29/124 (23%) Query: 68 PPGGGPSPGRHGPLPPPG--YGTPLNCNNNNGMGAAPKPFPGGTGPPIKAEPKAPYA--P 123 PP GG P GP PPPG G P N G P P GPP + K+ A P Sbjct: 223 PPQGGNQP--QGPPPPPGKPQGPPPQ-GGNKPQGPPPPGKP--QGPPAQGGSKSQSARSP 277 Query: 124 GTLPDSPPDSGSEAYSPQQVNEPHLLRTITPETLCHVGVPSRLEHPPPPPAHLPGPPPPP 183 P PP E +PQ P + P PPA G P P Sbjct: 278 PGKPQGPPQQ--EGNNPQGPPPP---------------AGGNPQQPQAPPA---GQPQGP 317 Query: 184 PPPP 187 P PP Sbjct: 318 PRPP 321 >gi|42544130 splicing factor 1 isoform 1 [Homo sapiens] Length = 639 Score = 64.7 bits (156), Expect = 5e-10 Identities = 75/273 (27%), Positives = 96/273 (35%), Gaps = 59/273 (21%) Query: 49 SYSHGQPAMPGSSGVHHLSPPGGGPSPGRHGPLPPPGYGTPLNCNNNNGMGAAPKPFPGG 108 S+ H P++ G G H + GP P P PPP M P P PG Sbjct: 396 SFPHPLPSLTGGHGGHPMQHNPNGPPPPWMQPPPPP-------------MNQGPHP-PGH 441 Query: 109 TGPPIKAEPKAPYAPGTLPDSPPDSGSEAYSPQQVNEPHLLRTITPETLCHVGVPSRLEH 168 GPP P Y L +P SG V H + + P P + Sbjct: 442 HGPP----PMDQY----LGSTPVGSG--------VYRLHQGKGMMPPP------PMGMMP 479 Query: 169 PPPPPAHLPGPPPPPPPPPHYPVLQRDLYMKAEPPIPHYAAMGQGLVPTDLHHTQQSQML 228 PPPPP G PPPPP P P Q+ PP P + +P + T + Sbjct: 480 PPPPPPS--GQPPPPPSGP-LPPWQQQQQQPPPPPPPSSSMASSTPLPWQQNTTTTT--- 533 Query: 229 HQLLQQHGAELPTHPSKKRKHSESPPSTLNAQMLNGMIKQEPGTVTALPLHP-TRAPSPP 287 +P ++ + SP + Q G T +PL P + P PP Sbjct: 534 ---TSAGTGSIPPWQQQQAAAAASPGA-----------PQMQGNPTMVPLPPGVQPPLPP 579 Query: 288 WPPQGPLSPGPGSLPLSIARVQTPPWHPPGAPS 320 P P P PGS + A PP PP PS Sbjct: 580 GAPPPPPPPPPGSAGMMYAPPPPPP--PPMDPS 610 >gi|116284398 WAS/WASL interacting protein family, member 1 [Homo sapiens] Length = 503 Score = 64.3 bits (155), Expect = 6e-10 Identities = 75/285 (26%), Positives = 98/285 (34%), Gaps = 53/285 (18%) Query: 29 SKEDASDLCFPDISAPASSASYSHGQPAMPGSSGVHHLSPPGGGPSPGRHGPLPPPGYGT 88 SK D+ P P S+ ++ G P +PG GP GP PPP G Sbjct: 178 SKPDSIPPPVPSTPRPIQSSPHNRGSPPVPG------------GPRQPSPGPTPPPFPG- 224 Query: 89 PLNCNNNNGMGAAP-KPFPGGTGPPIKAEPKAPYAPGTL-----PDSPPDSGSEAY---- 138 N +G + P + P P P P P PP G+ Sbjct: 225 ----NRGTALGGGSIRQSPLSSSSPFSNRPPLPPTPSRALDDKPPPPPPPVGNRPSIHRE 280 Query: 139 ----SPQQVNEPHLLRTITPETLCHVGVPSRLEHPPPPPAHLPGPPPPPP------PPPH 188 P Q N+P + T P S PPPPP PGPPP PP P Sbjct: 281 AVPPPPPQNNKPPVPSTPRPSA-------SSQAPPPPPPPSRPGPPPLPPSSSGNDETPR 333 Query: 189 YPVLQRDLYMKAE-PPIPHYAAMGQGLVPTDLHHTQQSQMLHQLLQQHGAELPTHPSKKR 247 P QR+L + + PP+P G P +++ + LP P R Sbjct: 334 LP--QRNLSLSSSTPPLPSPGRSG----PLPPPPSERPPPPVRDPPGRSGPLPPPPPVSR 387 Query: 248 KHSESP--PSTLNAQMLNGMIKQEPGTVTALPLHPTRAPSPPWPP 290 S S P+T +G+ G LP A +PP PP Sbjct: 388 NGSTSRALPATPQLPSRSGVDSPRSGPRPPLPPDRPSAGAPPPPP 432 Score = 52.4 bits (124), Expect = 2e-06 Identities = 80/333 (24%), Positives = 106/333 (31%), Gaps = 83/333 (24%) Query: 28 ISKEDASDLCFPDISAPASSASYSHGQPAMPGSSGVHHLSPPGGGPSPGRHGPLPPPGYG 87 + K +D P + P + + G G G GGG G G PPG G Sbjct: 46 LKKTVTNDRSAPILDKPKGAGAGGGGG----GFGGGGGFGGGGGGGGGGSFGGGGPPGLG 101 Query: 88 -----------TPLNCNNNNGMGAAPKPFPGGTGPPIKAEP-KAPYAPGTLPDSPPDSGS 135 + N +N++G G+ P P G G A+P P PG P P G Sbjct: 102 GLFQAGMPKLRSTANRDNDSG-GSRPPLLPPG-GRSTSAKPFSPPSGPGRFP--VPSPGH 157 Query: 136 EAYSPQQVNEPHLLRTITPETLCHVGVPSRLEHPPPPPAHLPGPPPPPPPPPHYP-VLQR 194 + P+ P R PPP P P PPP P P +Q Sbjct: 158 RSGPPE---------------------PQRNRMPPPRPDVGSKPDSIPPPVPSTPRPIQS 196 Query: 195 DLYMKAEPPIP------------------HYAAMGQGLVPTDLHHTQQSQMLHQLLQQHG 236 + + PP+P A+G G + +QS + + Sbjct: 197 SPHNRGSPPVPGGPRQPSPGPTPPPFPGNRGTALGGGSI-------RQSPLSSSSPFSNR 249 Query: 237 AELPTHPSKKRKHSESPPSTLNAQMLNGMIKQEPGTVTALPLHPTRAPSPPWPPQGPLSP 296 LP PS+ PP P +H R PP PPQ P Sbjct: 250 PPLPPTPSRALDDKPPPPP--------------PPVGNRPSIH--REAVPPPPPQNNKPP 293 Query: 297 GPGSLPLSIARVQTPPWHPPGAPSPGLLQDSDS 329 P + S + PP PP P P L S S Sbjct: 294 VPSTPRPSASSQAPPPPPPPSRPGPPPLPPSSS 326 Score = 52.0 bits (123), Expect = 3e-06 Identities = 45/141 (31%), Positives = 54/141 (38%), Gaps = 10/141 (7%) Query: 55 PAMPGSSGVHHLSPPGGGPSPGRHGPLPPPGYG---TPLNCNNNNGMGAA--PKPFPGGT 109 P+ P S PP PS PLPP G TP N + ++ P P PG + Sbjct: 295 PSTPRPSASSQAPPPPPPPSRPGPPPLPPSSSGNDETPRLPQRNLSLSSSTPPLPSPGRS 354 Query: 110 GPPIKAEPKAPYAPGTLPDSPPDSGSEAYSPQQVNEPHLLRTI--TPETLCHVGVPSRLE 167 GP P + P + D P SG P R + TP+ GV S Sbjct: 355 GP--LPPPPSERPPPPVRDPPGRSGPLPPPPPVSRNGSTSRALPATPQLPSRSGVDSPRS 412 Query: 168 HPPPP-PAHLPGPPPPPPPPP 187 P PP P P PPPPPP Sbjct: 413 GPRPPLPPDRPSAGAPPPPPP 433 >gi|38373695 WAS/WASL interacting protein family, member 1 [Homo sapiens] Length = 503 Score = 64.3 bits (155), Expect = 6e-10 Identities = 75/285 (26%), Positives = 98/285 (34%), Gaps = 53/285 (18%) Query: 29 SKEDASDLCFPDISAPASSASYSHGQPAMPGSSGVHHLSPPGGGPSPGRHGPLPPPGYGT 88 SK D+ P P S+ ++ G P +PG GP GP PPP G Sbjct: 178 SKPDSIPPPVPSTPRPIQSSPHNRGSPPVPG------------GPRQPSPGPTPPPFPG- 224 Query: 89 PLNCNNNNGMGAAP-KPFPGGTGPPIKAEPKAPYAPGTL-----PDSPPDSGSEAY---- 138 N +G + P + P P P P P PP G+ Sbjct: 225 ----NRGTALGGGSIRQSPLSSSSPFSNRPPLPPTPSRALDDKPPPPPPPVGNRPSIHRE 280 Query: 139 ----SPQQVNEPHLLRTITPETLCHVGVPSRLEHPPPPPAHLPGPPPPPP------PPPH 188 P Q N+P + T P S PPPPP PGPPP PP P Sbjct: 281 AVPPPPPQNNKPPVPSTPRPSA-------SSQAPPPPPPPSRPGPPPLPPSSSGNDETPR 333 Query: 189 YPVLQRDLYMKAE-PPIPHYAAMGQGLVPTDLHHTQQSQMLHQLLQQHGAELPTHPSKKR 247 P QR+L + + PP+P G P +++ + LP P R Sbjct: 334 LP--QRNLSLSSSTPPLPSPGRSG----PLPPPPSERPPPPVRDPPGRSGPLPPPPPVSR 387 Query: 248 KHSESP--PSTLNAQMLNGMIKQEPGTVTALPLHPTRAPSPPWPP 290 S S P+T +G+ G LP A +PP PP Sbjct: 388 NGSTSRALPATPQLPSRSGVDSPRSGPRPPLPPDRPSAGAPPPPP 432 Score = 52.4 bits (124), Expect = 2e-06 Identities = 80/333 (24%), Positives = 106/333 (31%), Gaps = 83/333 (24%) Query: 28 ISKEDASDLCFPDISAPASSASYSHGQPAMPGSSGVHHLSPPGGGPSPGRHGPLPPPGYG 87 + K +D P + P + + G G G GGG G G PPG G Sbjct: 46 LKKTVTNDRSAPILDKPKGAGAGGGGG----GFGGGGGFGGGGGGGGGGSFGGGGPPGLG 101 Query: 88 -----------TPLNCNNNNGMGAAPKPFPGGTGPPIKAEP-KAPYAPGTLPDSPPDSGS 135 + N +N++G G+ P P G G A+P P PG P P G Sbjct: 102 GLFQAGMPKLRSTANRDNDSG-GSRPPLLPPG-GRSTSAKPFSPPSGPGRFP--VPSPGH 157 Query: 136 EAYSPQQVNEPHLLRTITPETLCHVGVPSRLEHPPPPPAHLPGPPPPPPPPPHYP-VLQR 194 + P+ P R PPP P P PPP P P +Q Sbjct: 158 RSGPPE---------------------PQRNRMPPPRPDVGSKPDSIPPPVPSTPRPIQS 196 Query: 195 DLYMKAEPPIP------------------HYAAMGQGLVPTDLHHTQQSQMLHQLLQQHG 236 + + PP+P A+G G + +QS + + Sbjct: 197 SPHNRGSPPVPGGPRQPSPGPTPPPFPGNRGTALGGGSI-------RQSPLSSSSPFSNR 249 Query: 237 AELPTHPSKKRKHSESPPSTLNAQMLNGMIKQEPGTVTALPLHPTRAPSPPWPPQGPLSP 296 LP PS+ PP P +H R PP PPQ P Sbjct: 250 PPLPPTPSRALDDKPPPPP--------------PPVGNRPSIH--REAVPPPPPQNNKPP 293 Query: 297 GPGSLPLSIARVQTPPWHPPGAPSPGLLQDSDS 329 P + S + PP PP P P L S S Sbjct: 294 VPSTPRPSASSQAPPPPPPPSRPGPPPLPPSSS 326 Score = 52.0 bits (123), Expect = 3e-06 Identities = 45/141 (31%), Positives = 54/141 (38%), Gaps = 10/141 (7%) Query: 55 PAMPGSSGVHHLSPPGGGPSPGRHGPLPPPGYG---TPLNCNNNNGMGAA--PKPFPGGT 109 P+ P S PP PS PLPP G TP N + ++ P P PG + Sbjct: 295 PSTPRPSASSQAPPPPPPPSRPGPPPLPPSSSGNDETPRLPQRNLSLSSSTPPLPSPGRS 354 Query: 110 GPPIKAEPKAPYAPGTLPDSPPDSGSEAYSPQQVNEPHLLRTI--TPETLCHVGVPSRLE 167 GP P + P + D P SG P R + TP+ GV S Sbjct: 355 GP--LPPPPSERPPPPVRDPPGRSGPLPPPPPVSRNGSTSRALPATPQLPSRSGVDSPRS 412 Query: 168 HPPPP-PAHLPGPPPPPPPPP 187 P PP P P PPPPPP Sbjct: 413 GPRPPLPPDRPSAGAPPPPPP 433 >gi|146134388 YLP motif containing 1 [Homo sapiens] Length = 2146 Score = 63.5 bits (153), Expect = 1e-09 Identities = 74/269 (27%), Positives = 101/269 (37%), Gaps = 60/269 (22%) Query: 99 GAAPKPFPGGTGPPIKAEPKAPYAPG----TLPDSPPDSGSEAYSPQQVNEPHLLRTITP 154 G++ P P PP A P+A PG T P +P SG ++ Q + + L+ + Sbjct: 10 GSSHYPPPPVPPPPPVALPEASPGPGYSSSTTPAAPSSSGFMSFREQHLAQLQQLQQMHQ 69 Query: 155 ETLCHVGVPSRLEHPP-PPPAHLPG-------PPPPPPPPPHYPVLQRDLYMKAEPPIPH 206 + + V P L PP PPP +PG PPPPP PPP P L Sbjct: 70 KQMQCVLQPHHLPPPPLPPPPVMPGGGYGDWQPPPPPMPPPPGPALS------------- 116 Query: 207 YAAMGQGLVPTDLHHTQQSQMLHQLL-QQHGAELPTHPSKKRKHSESPPSTLNAQMLNGM 265 + +Q Q HQ+L Q P + ESPP + M Sbjct: 117 --------------YQKQQQYKHQMLHHQRDGPPGLVPMELESPPESPPVPPGSYM---- 158 Query: 266 IKQEPGTVTALPLHPTRAPSPPWPPQGPLSPGPGSLPLSIARVQTPPWHPPGAPSPGLLQ 325 P + + +P P PP P S P P + Q+PP AP+P Sbjct: 159 ----PPSQSYMP-----PPQPPPSYYPPTSSQPYLPPAQPSPSQSPPSQSYLAPTPS-YS 208 Query: 326 DSDSLSGSYLD------PNYQSIKWQPHQ 348 S S S SYL P+ Q+ +P Q Sbjct: 209 SSSSSSQSYLSHSQSYLPSSQASPSRPSQ 237 Score = 52.8 bits (125), Expect = 2e-06 Identities = 63/248 (25%), Positives = 87/248 (35%), Gaps = 51/248 (20%) Query: 64 HHLSPPGGGPSPGRHGPLPPPGYGTPLNCNNNNGMGAAPKPFPGGTGPPIKAEPKAPYAP 123 HHL PP PLPPP P GG G + P Sbjct: 79 HHLPPP----------PLPPP-----------------PVMPGGGYGD---------WQP 102 Query: 124 GTLPDSPPDSGSEAYSPQQVNEPHLL--RTITPETLCHVGVPSRLEHPPPPPAHLPGP-- 179 P PP + +Y QQ + +L + P L + + S E PP PP P Sbjct: 103 PPPPMPPPPGPALSYQKQQQYKHQMLHHQRDGPPGLVPMELESPPESPPVPPGSYMPPSQ 162 Query: 180 ---PPPPPPPPHYPVLQRDLYMKAEPPIPHYAAMGQG-LVPTDLH----HTQQSQMLH-Q 230 PPP PPP +YP Y+ P P + Q L PT + + QS + H Q Sbjct: 163 SYMPPPQPPPSYYPPTSSQPYLPPAQPSPSQSPPSQSYLAPTPSYSSSSSSSQSYLSHSQ 222 Query: 231 LLQQHGAELPTHPSKKRKHSE--SPPSTLNAQMLNGMIKQEPGTVTALPLHPTRAPSPPW 288 P+ PS+ S+ +PP ++QEP A + + P Sbjct: 223 SYLPSSQASPSRPSQGHSKSQLLAPPPPSAPPGNKTTVQQEPLESGAKNKSTEQQQAAPE 282 Query: 289 PPQGPLSP 296 P ++P Sbjct: 283 PDPSTMTP 290 Score = 45.1 bits (105), Expect = 4e-04 Identities = 57/227 (25%), Positives = 70/227 (30%), Gaps = 77/227 (33%) Query: 102 PKPFPGGTGPPIKAEPKAPYAPGTLPDSPPDSGSEAYSPQQVNEPHLLRTITPETLCHVG 161 P P P P + P P LP + P G P V P L ++ P G Sbjct: 527 PPPLPTMPPPVLPPSLPPPVMPPALPATVPPPGM----PPPVMPPSLPTSVPPP-----G 577 Query: 162 VPSRLEHPPPPPAHLP------GPPPPPPPPPHYPVLQRDLYMKAEPPIPHYAAMGQGLV 215 +P L PPP P GPPP PPP L A PP+ Sbjct: 578 MPPSLSSAGPPPVLPPPSLSSAGPPPVLPPP--------SLSSTAPPPV----------- 618 Query: 216 PTDLHHTQQSQMLHQLLQQHGAELPTHPSKKRKHSESPPSTLNAQMLNGMIKQEPGTVTA 275 +P P S +PP + PG Sbjct: 619 -----------------------MPLPPLS----SATPPPGI----------PPPGVPQG 641 Query: 276 LPLHPTRAPSPP----WPPQGPLSPGPGSLPLSIARVQTPP--WHPP 316 +P T AP PP Q P P P LP ++ PP +HPP Sbjct: 642 IPPQLTAAPVPPASSSQSSQVPEKPRPALLPTPVSFGSAPPTTYHPP 688 Score = 40.0 bits (92), Expect = 0.012 Identities = 44/163 (26%), Positives = 55/163 (33%), Gaps = 34/163 (20%) Query: 67 SPPGGGPSPGRHGPLPPPGY--GTPLNCNNNNGMGAAPKPFPGGTGPPIKAEPKAPYAPG 124 S PG P PG + P PP G G+ + + + P T PP+ P P P Sbjct: 1501 SRPGMYPPPGSYRPPPPMGKPPGSIVRPSAPPARSSVPV-----TRPPVPIPPPPP--PP 1553 Query: 125 TLPDSPPDSGSEAYSPQQV--------------NEPHLLRTITPETLCHVGVPSRLEHPP 170 LP PP + + +Q +E L ET P P Sbjct: 1554 PLPPPPPVIKPQTSAVEQERWDEDSFYGLWDTNDEQGLNSEFKSETAAIPSAPVL----P 1609 Query: 171 PPPAHLPGPPPPPPPPPHYPVLQRDLYMKAEPPIPHYAAMGQG 213 PPP H PPP P P P M PP+ G G Sbjct: 1610 PPPVHSSIPPPGPVPMGMPP-------MSKPPPVQQTVDYGHG 1645 Score = 37.7 bits (86), Expect = 0.061 Identities = 56/219 (25%), Positives = 84/219 (38%), Gaps = 30/219 (13%) Query: 55 PAMPGSSGVHHLSPPGGGPS---PGRHGPLPPPGYGTPLNCNNNNGMGAAPKPFPGGTGP 111 PA+P + + PPG P P +PPPG P + ++ P P GP Sbjct: 549 PALPAT-----VPPPGMPPPVMPPSLPTSVPPPGM--PPSLSSAGPPPVLPPPSLSSAGP 601 Query: 112 PIKAEPKAPYAPGTLPDSPPDSGSEAYSPQQVNEPHLLRTITPETLCHVGVP----SRLE 167 P P + + P P S A P + P + + I P+ L VP S+ Sbjct: 602 PPVLPPPSLSSTAPPPVMPLPPLSSATPPPGIPPPGVPQGIPPQ-LTAAPVPPASSSQSS 660 Query: 168 HPP--PPPAHLPGPPP--PPPPPPHYPVLQR---DLYMKAEPPIPHYA------AMGQGL 214 P P PA LP P PP ++P LQ + ++ P+ A + QGL Sbjct: 661 QVPEKPRPALLPTPVSFGSAPPTTYHPPLQSAGPSEQVNSKAPLSKSALPYSSFSSDQGL 720 Query: 215 VPTDLHHTQQSQMLHQLLQQHGAELPTHPSKKRKHSESP 253 + +Q + + + G LP P + + ESP Sbjct: 721 GESSAAPSQPITAVKDMPVRSGGLLPDPP--RSSYLESP 757 Score = 37.7 bits (86), Expect = 0.061 Identities = 28/89 (31%), Positives = 37/89 (41%), Gaps = 17/89 (19%) Query: 172 PPAHLPGPPPPPPPPPHYPVLQRDLYMKAEPPIPHYAAMGQGLVPTD----LHHTQQSQM 227 PP +P PPPPPP PP PV++ P +A+ Q D L T Q Sbjct: 1542 PPVPIPPPPPPPPLPPPPPVIK-----------PQTSAVEQERWDEDSFYGLWDTNDEQG 1590 Query: 228 LHQLLQQHGAELPTHP--SKKRKHSESPP 254 L+ + A +P+ P HS PP Sbjct: 1591 LNSEFKSETAAIPSAPVLPPPPVHSSIPP 1619 Score = 36.6 bits (83), Expect = 0.14 Identities = 84/365 (23%), Positives = 117/365 (32%), Gaps = 96/365 (26%) Query: 42 SAPASSASY-SHGQPAMPGSSGVHHLSPPGGGPSPGRHGPLPPPGYGTPLNCNNNNGMGA 100 S+ +SS SY SH Q +P S S P G S + PPP + N Sbjct: 209 SSSSSSQSYLSHSQSYLPSSQASP--SRPSQGHSKSQLLAPPPP------SAPPGNKTTV 260 Query: 101 APKPFPGGTGPPIKAEPKAPYAPGTLPDSPPDSGSEAY-----SPQQVNEPHL------- 148 +P G + +A P +P + Y S QQ + HL Sbjct: 261 QQEPLESGAKNKSTEQQQAAPEPDPSTMTPQEQQQYWYRQHLLSLQQRTKVHLPGHKKGP 320 Query: 149 -LRTITPETLCH-VGVPSRL--------EHPPPPPAHLPGPPPPPPPPPH---------- 188 + TPE + V VP+ E PP PP + PPP PP P Sbjct: 321 VVAKDTPEPVKEEVTVPATSQVPESPSSEEPPLPPPNEEVPPPLPPEEPQSEDPEEDARL 380 Query: 189 ----------------------------YPVLQRDL--YMKAEPPIPHYAAMGQGLVPTD 218 + LQ+ L Y + P PH M V Sbjct: 381 KQLQAAAAHWQQHQQHRVGFQYQGIMQKHTQLQQILQQYQQIIQPPPHIQTMS---VDMQ 437 Query: 219 LHHTQQSQMLHQLLQQH--------GAELPTHPSKK------------RKHSESPPSTLN 258 L H + Q Q L Q +L ++P K + H ++ S L Sbjct: 438 LRHYEMQQQQFQHLYQEWEREFQLWEEQLHSYPHKDQLQEYEKQWKTWQGHMKATQSYLQ 497 Query: 259 AQMLNGMIKQEPGTVTALPLHPTRAPSPPWPPQGPLSPGPGSLPLSIARVQTPPWHPPGA 318 + +N + + + + P P PP P P P LP S+ PP P Sbjct: 498 -EKVNSFQNMKNQYMGNMSMPPPFVPYSQMPPPLPTMP-PPVLPPSLPPPVMPPALPATV 555 Query: 319 PSPGL 323 P PG+ Sbjct: 556 PPPGM 560 Score = 33.1 bits (74), Expect = 1.5 Identities = 33/115 (28%), Positives = 44/115 (38%), Gaps = 34/115 (29%) Query: 83 PPGYGTPLNCNNNNGMGAAPKPFPGGTGPPIKAEPKAPYAPGTL--PDSPPDSGSEAYSP 140 PP N ++ GM P PG PP P PG++ P +PP Sbjct: 1490 PPQESRLQNTSSRPGM----YPPPGSYRPP----PPMGKPPGSIVRPSAPP--------- 1532 Query: 141 QQVNEPHLLRTITPETLCHVGVPSRLEHPPPPPAHLPGPPPPPPPPPHYPVLQRD 195 R+ P T V +P PPPPP P PPPPP P ++++ Sbjct: 1533 --------ARSSVPVTRPPVPIP-----PPPPP--PPLPPPPPVIKPQTSAVEQE 1572 >gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapiens] Length = 816 Score = 62.0 bits (149), Expect = 3e-09 Identities = 84/297 (28%), Positives = 110/297 (37%), Gaps = 61/297 (20%) Query: 41 ISAPASSASYSHG------QPAMPGSSGVHHLSPPGGGPSPGRHGPLPPPGYGTPLNCNN 94 +S+PA S + G P+ P G+ L PP P P P +PL Sbjct: 240 LSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPL---- 295 Query: 95 NNGMGAAPKPFPGGTGPPIKAEPKAPYAPGTLPDSPPDSGSEAYSPQQVNEPHLLRTITP 154 A P P + PP P AP + TLP P S+A + + P L T Sbjct: 296 -----ATPSP----SAPP---SPSAPPSLQTLPSPPATPPSQATT--SLGSPTLQAT--- 338 Query: 155 ETLCHVGVPSRLEHPPPPPAHLPGPPPPPPPPPHYPVLQRDLYMKAEPPIPHYAAMGQGL 214 H +PS PP + L PPP PP P LQ A PP+ A Sbjct: 339 ----HSFLPS------PPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLA------ 382 Query: 215 VPTDLHHTQQSQMLHQLLQQHGAELPTHPSKKRKHSESPPSTLNAQMLNGMIKQEPGTVT 274 T + +H LLQ A PS + SPP++ Q P ++ Sbjct: 383 --TPSPQAPNALAVH-LLQ---APFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLA 436 Query: 275 ALPLH--------PTRAPSPPWPPQGPLSPGPGSLPLSIARVQTPPWHPPGAPSPGL 323 A PL P +PS PPQ P P + PL +A+ PP PP +P L Sbjct: 437 APPLQVPPSPPASPPMSPSATPPPQAP--PPLAAPPLQLAK--PPPQAPPALATPPL 489 Score = 52.0 bits (123), Expect = 3e-06 Identities = 68/285 (23%), Positives = 93/285 (32%), Gaps = 47/285 (16%) Query: 66 LSPPGGGPSPGRHGPLPPPGYGTPLNCNNNNGMGAAPKPFPGGTGPPIKAEPKAPYAPGT 125 L P PSP PL P +P N + PF PP++A P++P Sbjct: 363 LPPLQAPPSPPASPPLSPLATPSP-QAPNALAVHLLQAPFSPPPSPPVQA----PFSPPA 417 Query: 126 LPDSPPDSGSEAYSPQQVNEPHLLRTITPETLCHVGVPSRLEHPPPPPAHLPGPPPPPPP 185 P P + + +P + P L + PP PPA P P PP Sbjct: 418 SPPVSPSATPPSQAPPSLAAPPL------------------QVPPSPPASPPMSPSATPP 459 Query: 186 PPHYPVLQRDLYMKAEPPIPHYAAMGQGLVPTDLHHTQQSQMLHQLLQQHGAELPTHPSK 245 P P L A+PP A+ T Q L + P PS Sbjct: 460 PQAPPPLAAPPLQLAKPPPQAPPALA----------TPPLQALPSPPASFPGQAPFSPSA 509 Query: 246 KRKHS--ESPPSTLNAQMLNGMIKQEPGTVTALPLHPTRAPSPPWPPQGPLSPGPGSLPL 303 S +PP + +++ P + L R P P P P L L Sbjct: 510 SLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGP---RLTL 566 Query: 304 SIARVQTPPWHPPGAPSPGLLQDSDSLSGSYLDPNYQSIKWQPHQ 348 ++A PG P P S +LSG L + S P + Sbjct: 567 ALA---------PGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEE 602 Score = 34.3 bits (77), Expect = 0.67 Identities = 30/88 (34%), Positives = 36/88 (40%), Gaps = 8/88 (9%) Query: 801 TTQLRQSPLTTGLPGIQPSLLLVTTSLTSSAPGSAVRTLDMCSSHPCPVICCSSPTTNPT 860 + L SPL T P P L + S P S TL P P P T+ Sbjct: 508 SASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASP--TLQAPRRPPTP-----GPDTS-V 559 Query: 861 TGPSLGPSFNPGHVLSPSPSPSTNRSGP 888 +GP L + PG PS SPS+ SGP Sbjct: 560 SGPRLTLALAPGPPPPPSRSPSSTLSGP 587 Score = 32.3 bits (72), Expect = 2.6 Identities = 36/129 (27%), Positives = 49/129 (37%), Gaps = 29/129 (22%) Query: 29 SKEDASDLCFPDISAPASSASYSHGQPAM--PGSSGVHHLSPPGGG------PSPGRHGP 80 S+ +S L PD++ +SSA+ + + G G SPP P+ GP Sbjct: 577 SRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGP 636 Query: 81 LPPPGYGTPLNCNNNNGMGAAPKPFPGGTGP----------PIKAEPKAPYAPGTLP--D 128 PP + G AP P+P TGP + A APG L Sbjct: 637 APPLAF---------RGAPGAPLPWPPATGPGSADGLCTIYETEGPESATPAPGALDPGP 687 Query: 129 SPPDSGSEA 137 SP SG +A Sbjct: 688 SPGTSGGKA 696 Score = 31.6 bits (70), Expect = 4.4 Identities = 74/307 (24%), Positives = 99/307 (32%), Gaps = 50/307 (16%) Query: 44 PASSASYSHGQPAMPGSSGVHHLSPPGGGPSPGRHGPLPPPGYGTPLNCNNNNGMGAAPK 103 P S+ + + P +SG +PP SPG P+ PG + + Sbjct: 71 PESAPRAGPTRTSRPPASGRGERAPPAKNTSPG---PVSSPGRAS-----------GTTR 116 Query: 104 PFP-GGTGPPIKAEPKAPYAPGTLPDSPPDSGSEAYSPQQVNEPHLLRTITPETLCHVGV 162 P P G G I AE A G ++P S A + + + P TP G Sbjct: 117 PGPLGQKGLRISAEETV--ARGKATEAPKRSALSAGARRDTSGP------TP------GT 162 Query: 163 PS----RLEHPPPPPAHLPGPPP-----PPPPPPHYPVLQRDLYMKAEPP--IPHYAAMG 211 PS R LP P P PP P V + EP + G Sbjct: 163 PSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAG 222 Query: 212 QGLVPTDLHHTQQSQMLHQLLQQHGAELPTHPSKKRKHSESPPSTLNAQMLNGMIKQEPG 271 GL S + G P S+ P L A + Sbjct: 223 GGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKD 282 Query: 272 TVTAL-PLH--PTRAPSPPWPPQGPLSPGPGSLPLSIARVQTPPWHPPGAPSPGLLQDSD 328 AL PL P PSP PP SP S P S+ + +PP PP + L + Sbjct: 283 AAPALGPLSSSPLATPSPSAPP----SP---SAPPSLQTLPSPPATPPSQATTSLGSPTL 335 Query: 329 SLSGSYL 335 + S+L Sbjct: 336 QATHSFL 342 >gi|48255900 SWI/SNF-related matrix-associated actin-dependent regulator of chromatin a2 isoform a [Homo sapiens] Length = 1590 Score = 61.2 bits (147), Expect = 5e-09 Identities = 93/339 (27%), Positives = 115/339 (33%), Gaps = 63/339 (18%) Query: 41 ISAPASSASYSHGQPAM-PGSSGVHHLSP-PGGGPSPG----RHGPLP-PPGYGTPLNCN 93 +S P + H P+ PG S L P PG GPSPG GP P PP P+ Sbjct: 1 MSTPTDPGAMPHPGPSPGPGPSPGPILGPSPGPGPSPGSVHSMMGPSPGPPSVSHPMPTM 60 Query: 94 NN-----NGMGAAPKPFPGGTGPPI---------KAEPKAPYAPGT-LPDSPPDSGSEAY 138 + GM KP G I K P PG P SP D S+ Y Sbjct: 61 GSTDFPQEGMHQMHKPIDGIHDKGIVEDIHCGSMKGTGMRPPHPGMGPPQSPMDQHSQGY 120 Query: 139 SPQQVNEPHLLRTITPETLCHVGVPSRLEHPPPPP-------AHLPGPP-----PPPPPP 186 PH PE HV P P PP A +PG P P P Sbjct: 121 M-----SPHPSPLGAPE---HVSSPMSGGGPTPPQMPPSQPGALIPGDPQAMSQPNRGPS 172 Query: 187 PHYPVLQRDL--------YMKAEPPIP---HYAAMGQGLVP---TDLHHTQQSQMLHQLL 232 P PV L + P+P A G+ +P QQ Q Q Sbjct: 173 PFSPVQLHQLRAQILAYKMLARGQPLPETLQLAVQGKRTLPGLQQQQQQQQQQQQQQQQQ 232 Query: 233 QQHGAELPTHPSKKRKHSESPPSTLNAQMLNGMIKQEPGTVTALPLHPTRAPSP-PWPPQ 291 QQ + P + + + P+ +N +G PG + P P + P P P Sbjct: 233 QQQQQQPQQQPPQPQTQQQQQPALVNYNRPSG-----PGPELSGPSTPQKLPVPAPGGRP 287 Query: 292 GPLSPGPGSLPLSIARVQTPPWHPPGAPSPGL-LQDSDS 329 P P P + + P PG PSP L LQ S Sbjct: 288 SPAPPAAAQPPAAAVPGPSVPQPAPGQPSPVLQLQQKQS 326 Score = 33.9 bits (76), Expect = 0.88 Identities = 17/37 (45%), Positives = 20/37 (54%), Gaps = 5/37 (13%) Query: 853 SSPTTNPTTGPSLGPSFNPGHVLSPSPSPSTNRSGPS 889 + P P GPS GP +PG +L PSP P GPS Sbjct: 5 TDPGAMPHPGPSPGPGPSPGPILGPSPGP-----GPS 36 >gi|48255898 SWI/SNF-related matrix-associated actin-dependent regulator of chromatin a2 isoform b [Homo sapiens] Length = 1572 Score = 61.2 bits (147), Expect = 5e-09 Identities = 93/339 (27%), Positives = 115/339 (33%), Gaps = 63/339 (18%) Query: 41 ISAPASSASYSHGQPAM-PGSSGVHHLSP-PGGGPSPG----RHGPLP-PPGYGTPLNCN 93 +S P + H P+ PG S L P PG GPSPG GP P PP P+ Sbjct: 1 MSTPTDPGAMPHPGPSPGPGPSPGPILGPSPGPGPSPGSVHSMMGPSPGPPSVSHPMPTM 60 Query: 94 NN-----NGMGAAPKPFPGGTGPPI---------KAEPKAPYAPGT-LPDSPPDSGSEAY 138 + GM KP G I K P PG P SP D S+ Y Sbjct: 61 GSTDFPQEGMHQMHKPIDGIHDKGIVEDIHCGSMKGTGMRPPHPGMGPPQSPMDQHSQGY 120 Query: 139 SPQQVNEPHLLRTITPETLCHVGVPSRLEHPPPPP-------AHLPGPP-----PPPPPP 186 PH PE HV P P PP A +PG P P P Sbjct: 121 M-----SPHPSPLGAPE---HVSSPMSGGGPTPPQMPPSQPGALIPGDPQAMSQPNRGPS 172 Query: 187 PHYPVLQRDL--------YMKAEPPIP---HYAAMGQGLVP---TDLHHTQQSQMLHQLL 232 P PV L + P+P A G+ +P QQ Q Q Sbjct: 173 PFSPVQLHQLRAQILAYKMLARGQPLPETLQLAVQGKRTLPGLQQQQQQQQQQQQQQQQQ 232 Query: 233 QQHGAELPTHPSKKRKHSESPPSTLNAQMLNGMIKQEPGTVTALPLHPTRAPSP-PWPPQ 291 QQ + P + + + P+ +N +G PG + P P + P P P Sbjct: 233 QQQQQQPQQQPPQPQTQQQQQPALVNYNRPSG-----PGPELSGPSTPQKLPVPAPGGRP 287 Query: 292 GPLSPGPGSLPLSIARVQTPPWHPPGAPSPGL-LQDSDS 329 P P P + + P PG PSP L LQ S Sbjct: 288 SPAPPAAAQPPAAAVPGPSVPQPAPGQPSPVLQLQQKQS 326 Score = 33.9 bits (76), Expect = 0.88 Identities = 17/37 (45%), Positives = 20/37 (54%), Gaps = 5/37 (13%) Query: 853 SSPTTNPTTGPSLGPSFNPGHVLSPSPSPSTNRSGPS 889 + P P GPS GP +PG +L PSP P GPS Sbjct: 5 TDPGAMPHPGPSPGPGPSPGPILGPSPGP-----GPS 36 >gi|160707881 formin 2 [Homo sapiens] Length = 1722 Score = 60.8 bits (146), Expect = 7e-09 Identities = 87/291 (29%), Positives = 103/291 (35%), Gaps = 74/291 (25%) Query: 55 PAMPGSSGVHHLSP-PGGG-----PSPGRHGPLPPP--GYGTPLNCNNNNGMGAAPKPFP 106 P +PG+ G+ L P PG G P PG P PPP G G PL P P P Sbjct: 924 PPLPGA-GILPLPPLPGAGIPPPPPLPGAAIPPPPPLPGAGIPL-----------PPPLP 971 Query: 107 GGTGPPIKAEPKA-----PYAPGT-LPDSPPDSGSEAYSPQQVNEPHLLRTITPETLCHV 160 G PP P A P PG +P PP G+ P + + P L Sbjct: 972 GAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIP---PPPPLPGA 1028 Query: 161 GVPSRLEHPPPPPAHLPGPPPPP-------PPPPHYPVLQRDLYMKAEPPIPHYAAMGQG 213 G+P PPPP G PPPP PPPP P + PP+P G G Sbjct: 1029 GIP------PPPPLPGAGIPPPPPLPGAGIPPPPPLP----GAGIPPPPPLP-----GAG 1073 Query: 214 LVPTDLHHTQQSQMLHQLLQQHGAELPTHPSKKRKHSESPPSTLNAQMLNGMIKQEPGTV 273 + P GA +P P PP G+ P Sbjct: 1074 IPPPP--------------PLPGAGIPPPPPLPGAGIPPPPPLPGV----GIPPPPPLPG 1115 Query: 274 TALPLHPTRAPSPPWPPQGPLSPGPG-SLPLSIARVQTPPWHPPGAPSPGL 323 +P P P PP PL PG G P + RV PP PP P G+ Sbjct: 1116 AGIP-PPPPLPGAGIPPPPPL-PGAGIPPPPPLPRVGIPP--PPPLPGAGI 1162 Score = 57.8 bits (138), Expect = 6e-08 Identities = 73/262 (27%), Positives = 89/262 (33%), Gaps = 77/262 (29%) Query: 55 PAMPGSSGVHHLSPPGGGPSPGRHGPLPPPGYGTPLNCNNNNGMGAAPKPFPGGTGPPIK 114 P +PG+ + PP P G P P PG G P P P PG PP Sbjct: 1045 PPLPGAG----IPPPPPLPGAGIPPPPPLPGAGIP-----------PPPPLPGAGIPPPP 1089 Query: 115 AEPKA-----PYAPGT-LPDSPPDSGSEAYSPQQVNEPHLLRTITPETLCHVGVPSRLEH 168 P A P PG +P PP G+ P + + P L G+P Sbjct: 1090 PLPGAGIPPPPPLPGVGIPPPPPLPGAGIPPPPPLPGAGIP---PPPPLPGAGIP----- 1141 Query: 169 PPPPPAHLPGPPPPPP------PPPHYPVLQRDLYMKAEPPIPHYAAMGQGLVPTDLHHT 222 PPPP G PPPPP PPP PP+P G G+ P Sbjct: 1142 -PPPPLPRVGIPPPPPLPGAGIPPP--------------PPLP-----GAGIPPPP---- 1177 Query: 223 QQSQMLHQLLQQHGAELPTHPSKKRKHSESPPSTLNAQMLNGMIKQEPGTVTALPLHPTR 282 G +P P PP L G P + + + P Sbjct: 1178 ----------PLPGVGIPPPPPLPGVGIPPPPP------LPGAGIPPPPPLPGMGIPP-- 1219 Query: 283 APSPPWPPQGPLSPGPGSLPLS 304 AP+PP PP G P P LP+S Sbjct: 1220 APAPPLPPPGTGIPPPPLLPVS 1241 Score = 45.1 bits (105), Expect = 4e-04 Identities = 75/299 (25%), Positives = 95/299 (31%), Gaps = 75/299 (25%) Query: 40 DISAPASSASYSHGQPAMPGSSGVHHLSPPGGGPSPGRHGPLPPPGYGTPLNCNNNNGMG 99 D P S S P++ S+G G+ G PP T ++ + + Sbjct: 799 DSHQPTQSISQPPPPPSLLWSAG------------QGQPGSQPPHSISTEFQTSHEHSVS 846 Query: 100 AAPK-----PFPGGTGPPIKAEPKAPYAPGTLPDSPPDSGSEAYSPQQVNEPHLLRTITP 154 +A K P P PP+ + PG PP P L +T Sbjct: 847 SAFKNSCNIPSP----PPLPCTESSSSMPGLGMVPPP--------------PPPLPGMTV 888 Query: 155 ETLCHVGVPSR-----LEHPPPPPAHLPGPPPPPPPP-PHYPVLQRDLYMKAEPPIPHYA 208 TL +P E PPPP LPG PPPPP P +L PP+P Sbjct: 889 PTLPSTAIPQPPPLQGTEMLPPPPPPLPGAGIPPPPPLPGAGILPL-------PPLP--- 938 Query: 209 AMGQGLVPTDLHHTQQSQMLHQLLQQHGAELPTHPSKKRKHSESPPSTLNAQMLNGMIKQ 268 G G+ P GA +P P PP A + Sbjct: 939 --GAGIPPPP--------------PLPGAAIPPPPPLPGAGIPLPPPLPGAGIPPPPPLP 982 Query: 269 EPGTVTALPLHPTRAPSPPWPPQGPLSPGPGSLPLSIARVQTPP-----WHPPGAPSPG 322 G PL P PP P + P P PL A + PP PP P PG Sbjct: 983 GAGIPPPPPLPGAGIPPPPPLPGAGIPPPP---PLPGAGIPPPPPLPGAGIPPPPPLPG 1038 >gi|117306167 proline-rich protein BstNI subfamily 3 precursor [Homo sapiens] Length = 309 Score = 60.8 bits (146), Expect = 7e-09 Identities = 76/289 (26%), Positives = 91/289 (31%), Gaps = 68/289 (23%) Query: 44 PASSASYSHGQPAMPGSSGVHHLSPPGGGPSPGRHGPLPPPGYGTPLNCNNNNG-MGAAP 102 P + S G P PG P G P G PPP G P G P Sbjct: 61 PPQGGNQSQGPPPRPGK-------PEGPPPQGGNQSQGPPPRPGKPEGQPPQGGNQSQGP 113 Query: 103 KPFPGGT-GPPIKAEPKA---PYAPGTLPDSPPDSGSEAYSPQQVNEPHLLRTITPETLC 158 P PG GPP + ++ P PG PP G+++ P Sbjct: 114 PPRPGKPEGPPPQGGNQSQGPPPRPGKPEGPPPQGGNQSQGPPPR--------------- 158 Query: 159 HVGVPSRLEHPPPPPAHLPGPPPPPPPPPHYPVLQRDLYMKAEPPIPHYAAMGQGLVPTD 218 P + E PPP + PPP P P P Q + PP P +G P Sbjct: 159 ----PGKPEGPPPQGGNQSQGPPPHPGKPEGPPPQGGNQSQGPPPRP---GKPEGPPPQG 211 Query: 219 LHHTQQSQMLHQLLQQHGAELPTHPSKKRKHSESPPSTLNAQMLNGMIKQEPGTVTALPL 278 + +Q P P K E PPS G Q P P Sbjct: 212 GNQSQGP--------------PPRPGKP----EGPPSQ------GGNKPQGPPPHPGKPQ 247 Query: 279 HPT-------RAPSPPWPPQGPLSPGPG---SLPLSIARVQTPPWHPPG 317 P + P PP PQGP PG LP + Q PP P G Sbjct: 248 GPPPQEGNKPQRPPPPGRPQGPPPPGGNPQQPLPPPAGKPQGPPPPPQG 296 Score = 53.9 bits (128), Expect = 8e-07 Identities = 48/157 (30%), Positives = 53/157 (33%), Gaps = 30/157 (19%) Query: 44 PASSASYSHGQPAMPGSSGVHHLSPPGGGPSPGRHGPLPPPGYGTPLNCNNNNG-MGAAP 102 P + S G P PG P G P G PPP G P G P Sbjct: 166 PPQGGNQSQGPPPHPGK-------PEGPPPQGGNQSQGPPPRPGKPEGPPPQGGNQSQGP 218 Query: 103 KPFPGGT-GPPIKAEPKA---PYAPGTLPDSPPDSGSEAYSPQQVNEPHLLRTITPETLC 158 P PG GPP + K P PG PP G++ P P Sbjct: 219 PPRPGKPEGPPSQGGNKPQGPPPHPGKPQGPPPQEGNKPQRPPPPGRPQ----------- 267 Query: 159 HVGVP---SRLEHPPPPPAHLPGPPPPPPP--PPHYP 190 G P + P PPPA P PPPPP PH P Sbjct: 268 --GPPPPGGNPQQPLPPPAGKPQGPPPPPQGGRPHRP 302 Score = 49.3 bits (116), Expect = 2e-05 Identities = 45/147 (30%), Positives = 52/147 (35%), Gaps = 29/147 (19%) Query: 44 PASSASYSHGQPAMPGSSGVHHLSPPGGGPSPGRHGPLPPPGYGTPLNCNNNNG-MGAAP 102 P + S G P PG P G P G PPP G P + G P Sbjct: 187 PPQGGNQSQGPPPRPGK-------PEGPPPQGGNQSQGPPPRPGKPEGPPSQGGNKPQGP 239 Query: 103 KPFPGGT-GPPIKA--EPKAPYAPGTLPDSPPDSGSEAYSPQQVNEPHLLRTITPETLCH 159 P PG GPP + +P+ P PG P PP G +PQQ P + P Sbjct: 240 PPHPGKPQGPPPQEGNKPQRPPPPGR-PQGPPPPGG---NPQQPLPPPAGKPQGP----- 290 Query: 160 VGVPSRLEHPPPPPAHLPGPPPPPPPP 186 PPPP P PP PP Sbjct: 291 ---------PPPPQGGRPHRPPQGQPP 308 >gi|51702526 Wiskott-Aldrich syndrome gene-like protein [Homo sapiens] Length = 505 Score = 60.5 bits (145), Expect = 9e-09 Identities = 62/208 (29%), Positives = 79/208 (37%), Gaps = 46/208 (22%) Query: 67 SPPGGGPSPGRHGPLPPPGYGTPLNCNNNNGMGAAPKPFPGGTGPPIKAEPKAPYAPGTL 126 +PP PS G P PPP + + G P P G PP P AP Sbjct: 276 APPPPPPSRGGPPPPPPPPHNS----------GPPPPPARGRGAPP----PPPSRAPTAA 321 Query: 127 PDSPPDSGSEAYSPQQVNEPHLLRTITPETLCHVGVPSRLEHPPPPPAHLPG------PP 180 P PP S P P+ + P L S PPPPP + G PP Sbjct: 322 PPPPPPSRPSVAVPPP--PPNRMYPPPPPAL----PSSAPSGPPPPPPSVLGVGPVAPPP 375 Query: 181 PPPPPPPHYPVLQRDLYMKAEPPIPHYAAMGQGLVPTDLHHTQQSQMLHQLLQQHGAELP 240 PPPPPPP P PP P + G VPT + ++ +L Q+ + GA+L Sbjct: 376 PPPPPPPPGP-----------PPPPGLPSDGDHQVPTTAGN--KAALLDQI--REGAQL- 419 Query: 241 THPSKKRKHSESPPSTLNAQMLNGMIKQ 268 KK + + P S L I+Q Sbjct: 420 ----KKVEQNSRPVSCSGRDALLDQIRQ 443 Score = 59.3 bits (142), Expect = 2e-08 Identities = 55/166 (33%), Positives = 62/166 (37%), Gaps = 44/166 (26%) Query: 165 RLEHPPPPPAHLPGPPPPPPPPPHYPVLQRDLYMKAEPPIPHYAAMGQGLVPTDLHHTQQ 224 R + PPPPP GPPPPPPPP + PP P A G+G P Sbjct: 273 RRQAPPPPPPSRGGPPPPPPPP----------HNSGPPPPP---ARGRGAPPPPPSRAPT 319 Query: 225 SQMLHQLLQQHGAELPTHPSKKRKHSESPPSTLNAQMLNGMIKQEPGTVTALPLHPTRAP 284 + A P PS+ PP N M P P P+ AP Sbjct: 320 A-----------APPPPPPSRPSVAVPPPPP-------NRMYPPPP------PALPSSAP 355 Query: 285 S-PPWPPQGPLSPGPGSLPLSIARVQTPPWHPPG-APSPGLLQDSD 328 S PP PP L GP + P PP PPG P PGL D D Sbjct: 356 SGPPPPPPSVLGVGPVAPP-----PPPPPPPPPGPPPPPGLPSDGD 396 Score = 54.3 bits (129), Expect = 6e-07 Identities = 46/134 (34%), Positives = 50/134 (37%), Gaps = 21/134 (15%) Query: 55 PAMPGSSGVHHLSPPGGGPSPGRHGPLPPP--GYGTPLNCNNNNGMGAAPKPFPGGTGPP 112 P P S G PP P P GP PPP G G P + A P P P + P Sbjct: 278 PPPPPSRG----GPPPPPPPPHNSGPPPPPARGRGAPPPPPSRAPTAAPPPPPP--SRPS 331 Query: 113 IKAEPKAPYAPGTLPDSPPDSGSEAYSPQQVNEPHLLRTITPETLCHVGVPSRLEHPPPP 172 + P P P PP S A S P +L GV PPPP Sbjct: 332 VAVPPPPPNR--MYPPPPPALPSSAPSGPPPPPPSVL-----------GVGPVAPPPPPP 378 Query: 173 PAHLPGPPPPPPPP 186 P PGPPPPP P Sbjct: 379 PPPPPGPPPPPGLP 392 Score = 40.0 bits (92), Expect = 0.012 Identities = 39/152 (25%), Positives = 43/152 (28%), Gaps = 53/152 (34%) Query: 39 PDISAPASSASYSHGQPAMPGSSGVHHLSPPGGGPSPGRHGPLPPPGYGTPLNCNNNNGM 98 P S P + G P P S PP P P PPP P Sbjct: 294 PHNSGPPPPPARGRGAPPPPPSRAPTAAPPPPPPSRPSVAVPPPPPNRMYP--------- 344 Query: 99 GAAPKPFPGGTGPPIKAEPKAPYAPGTLPDSPPDSGSEAYSPQQVNEPHLLRTITPETLC 158 P P P + P PP P ++ Sbjct: 345 ------------------PPPPALPSSAPSGPPP--------------------PPPSVL 366 Query: 159 HVGVPSRLEHPPPPPAHLPGPPPPPPPPPHYP 190 VG P PPPPP PPP PPPPP P Sbjct: 367 GVG-PVAPPPPPPPP-----PPPGPPPPPGLP 392 >gi|19718731 bromodomain-containing protein 4 isoform long [Homo sapiens] Length = 1362 Score = 60.5 bits (145), Expect = 9e-09 Identities = 56/175 (32%), Positives = 69/175 (39%), Gaps = 25/175 (14%) Query: 163 PSRLEHPPPPPAHLPGPPPPPPPPPHYPVLQRDLYMKAEPP------IPHYAAMGQGLVP 216 P + PPPPP PPPPPPPP P Q MK+ PP +P G V Sbjct: 759 PPPQQPPPPPPPQQQQQPPPPPPPPSMP-QQAAPAMKSSPPPFIATQVPVLEPQLPGSVF 817 Query: 217 TDLHHTQQSQMLHQLLQQHGAELPTHPSKKRKHSESPPSTLNAQMLNGMIKQEPGTVTAL 276 + H Q +L ELP H + +HS P +A + P AL Sbjct: 818 DPIGHFTQ-----PILHLPQPELPPHLPQPPEHSTPPHLNQHA------VVSPPALHNAL 866 Query: 277 PLHPTRAPSPPWPPQGPLSPGPGSLP-LSIARVQTP--PWHPPGAPSPGLLQDSD 328 P P+R P L P P P +S A QTP P P P LL+D + Sbjct: 867 PQQPSR----PSNRAAALPPKPARPPAVSPALTQTPLLPQPPMAQPPQVLLEDEE 917 Score = 51.6 bits (122), Expect = 4e-06 Identities = 74/309 (23%), Positives = 101/309 (32%), Gaps = 64/309 (20%) Query: 54 QPAMPGSSGVHHLSPPGGGPSP--GRHGPLPPPGYGTPL----NCNNNNGMGAAPKPF-P 106 QP +P H PP P +H + PP L + +N PKP P Sbjct: 832 QPELPP----HLPQPPEHSTPPHLNQHAVVSPPALHNALPQQPSRPSNRAAALPPKPARP 887 Query: 107 GGTGPPIKAEPKAPYAPGTLPDSPPDSGSEAYSPQQVNEPHLLRTITPETLCHVGVPSRL 166 P + P P P PP E P + + + L V P+ Sbjct: 888 PAVSPALTQTPLLPQPPMA---QPPQVLLEDEEPPAPPLTSMQMQLYLQQLQKVQPPT-- 942 Query: 167 EHPPPPPAHLPGPPPPPPPPPHYPVLQRDLYMKAEPPIPHYAAMGQGLVPTDLHHTQQSQ 226 P P + PPPP PPP +P +Q+ L + PP P Q P H + Sbjct: 943 --PLLPSVKVQSQPPPPLPPPPHPSVQQQLQQQPPPPPP-----PQPQPPPQQQHQPPPR 995 Query: 227 MLHQLLQQHGAELPTHPSKKRKHSESPPSTLNAQMLNGMIKQEPGTVTALPLHPTRAPSP 286 +H P + H + PP P + P Sbjct: 996 PVH-----------LQPMQFSTHIQQPP-------------------------PPQGQQP 1019 Query: 287 PWPPQG--PLSPGPGSLPLSIARVQTPPWHPPGAPSPGLLQDSDS--LSGSYLDPNYQSI 342 P PP G P P P I +P H S G L+++ S + S +QS+ Sbjct: 1020 PHPPPGQQPPPPQPAKPQQVIQHHHSPRHHKSDPYSTGHLREAPSPLMIHSPQMSQFQSL 1079 Query: 343 KWQ-PHQQN 350 Q P QQN Sbjct: 1080 THQSPPQQN 1088 Score = 47.0 bits (110), Expect = 1e-04 Identities = 65/252 (25%), Positives = 84/252 (33%), Gaps = 31/252 (12%) Query: 93 NNNNGMGAAPKPFPGGTGPPIKAEPKAP----YAPGTLPDSPPDSGSEAYSPQQVNEPHL 148 +++ M AP P P PP + P P P PP +A + + P Sbjct: 741 HHHQQMQQAPAPVPQQPPPPPQQPPPPPPPQQQQQPPPPPPPPSMPQQAAPAMKSSPPPF 800 Query: 149 LRTITP--ETLCHVGVPSRLEHPPPPPAHLPGPPPP---PPPPPHYPVLQRDLYMKAEPP 203 + T P E V + H P HLP P P P PP H + + PP Sbjct: 801 IATQVPVLEPQLPGSVFDPIGHFTQPILHLPQPELPPHLPQPPEHSTPPHLNQHAVVSPP 860 Query: 204 IPHYAAMGQ---------GLVPTDLHHTQQSQMLHQ--LLQQHGAELPTHPSKKRKHSES 252 H A Q L P S L Q LL Q P + + + Sbjct: 861 ALHNALPQQPSRPSNRAAALPPKPARPPAVSPALTQTPLLPQPPMAQPPQVLLEDEEPPA 920 Query: 253 PPSTLNAQM---LNGMIKQEPGTVTALPLHPTRAPSPPWPPQGPLSPGPGSLPLSIARVQ 309 PP T + QM L + K +P T + P PP PP P + Q Sbjct: 921 PPLT-SMQMQLYLQQLQKVQPPTPLLPSVKVQSQPPPPLPP-------PPHPSVQQQLQQ 972 Query: 310 TPPWHPPGAPSP 321 PP PP P P Sbjct: 973 QPPPPPPPQPQP 984 Score = 41.6 bits (96), Expect = 0.004 Identities = 29/92 (31%), Positives = 41/92 (44%), Gaps = 8/92 (8%) Query: 115 AEPKAPYAPGTLPDS-PPDSGSEAYSPQQVNE-PHLLRTITPETLCHVGVPSRLEHPPPP 172 A+P P T S PP + + +P V PH +TP+ + V + + PP Sbjct: 189 AKPGVSTVPNTTQASTPPQTQTPQPNPPPVQATPHPFPAVTPDLIVQTPVMTVV---PPQ 245 Query: 173 PAHLPGPPPPPPPPPHYPVLQRDLYMKAEPPI 204 P P P PP P PP P Q +++ PPI Sbjct: 246 PLQTPPPVPPQPQPPPAPAPQP---VQSHPPI 274 Score = 33.5 bits (75), Expect = 1.1 Identities = 43/157 (27%), Positives = 56/157 (35%), Gaps = 23/157 (14%) Query: 56 AMPGSSGVHHLSPPGGGPSPGRHGPLPPPGYGTPL-------NCNNNNGMGAAPKPFPGG 108 A PG S V + + P P PPP TP + + P P Sbjct: 189 AKPGVSTVPNTTQASTPPQTQTPQPNPPPVQATPHPFPAVTPDLIVQTPVMTVVPPQPLQ 248 Query: 109 TGPPIKAEPKAPYAPGTLP--DSPPDSGSEAYSPQQVNEPHLLR----TITPETLCHVGV 162 T PP+ +P+ P AP P PP A +PQ V ++ T TP T+ + Sbjct: 249 TPPPVPPQPQPPPAPAPQPVQSHPP---IIAATPQPVKTKKGVKRKADTTTPTTIDPIHE 305 Query: 163 PSRLEHPPPPPAHLPG-----PPPPPPPPPHYPVLQR 194 P L PP P G P PP P Q+ Sbjct: 306 PPSL--PPEPKTTKLGQRRESSRPVKPPKKDVPDSQQ 340 Score = 31.2 bits (69), Expect = 5.7 Identities = 24/81 (29%), Positives = 38/81 (46%), Gaps = 12/81 (14%) Query: 265 MIKQEPGTVTALPLHPTRAPSPPWPPQGPLSPGPGSLPLSIARVQTPPWHPPGAPSP--- 321 +I Q P +T +P P + P PP PPQ P P P VQ+ P P P Sbjct: 232 LIVQTP-VMTVVPPQPLQTP-PPVPPQPQPPPAPAPQP-----VQSHPPIIAATPQPVKT 284 Query: 322 --GLLQDSDSLSGSYLDPNYQ 340 G+ + +D+ + + +DP ++ Sbjct: 285 KKGVKRKADTTTPTTIDPIHE 305 >gi|42544125 splicing factor 1 isoform 2 [Homo sapiens] Length = 638 Score = 59.3 bits (142), Expect = 2e-08 Identities = 69/258 (26%), Positives = 90/258 (34%), Gaps = 57/258 (22%) Query: 49 SYSHGQPAMPGSSGVHHLSPPGGGPSPGRHGPLPPPGYGTPLNCNNNNGMGAAPKPFPGG 108 S+ H P++ G G H + GP P P PPP M P P PG Sbjct: 396 SFPHPLPSLTGGHGGHPMQHNPNGPPPPWMQPPPPP-------------MNQGPHP-PGH 441 Query: 109 TGPPIKAEPKAPYAPGTLPDSPPDSGSEAYSPQQVNEPHLLRTITPETLCHVGVPSRLEH 168 GPP P Y L +P SG V H + + P P + Sbjct: 442 HGPP----PMDQY----LGSTPVGSG--------VYRLHQGKGMMPPP------PMGMMP 479 Query: 169 PPPPPAHLPGPPPPPPPPPHYPVLQRDLYMKAEPPIPHYAAMGQGLVPTDLHHTQQSQML 228 PPPPP G PPPPP P P Q+ PP P + +P + T + Sbjct: 480 PPPPPPS--GQPPPPPSGP-LPPWQQQQQQPPPPPPPSSSMASSTPLPWQQNTTTTT--- 533 Query: 229 HQLLQQHGAELPTHPSKKRKHSESPPSTLNAQMLNGMIKQEPGTVTALPLHP-TRAPSPP 287 +P ++ + SP + Q G T +PL P + P PP Sbjct: 534 ---TSAGTGSIPPWQQQQAAAAASPGA-----------PQMQGNPTMVPLPPGVQPPLPP 579 Query: 288 WPPQGPLSPGPGSLPLSI 305 P P P PGS + I Sbjct: 580 GAPPPPPPPPPGSAGMMI 597 Score = 46.2 bits (108), Expect = 2e-04 Identities = 65/266 (24%), Positives = 85/266 (31%), Gaps = 73/266 (27%) Query: 55 PAMPGSSGVHHLSPPGGGPSPGRHGPLPPPGYGTPLNCNNNNGMGAAP---KPFPGGTGP 111 PA GS+ +P P P PPP + M + P +P+ G G Sbjct: 326 PASVGSTSGPATTPLASAPRPAAPANNPPPPSLMSTTQSRPPWMNSGPSESRPYHGMHGG 385 Query: 112 PIKAEPKAPYAPGTLPDSPPDSGSEAYSPQQVNEPHLLRTITPETLCHVGVPSRLEHPPP 171 P PG P S PH L ++T H G P + P Sbjct: 386 -------GPGGPGGGPHS---------------FPHPLPSLTGG---HGGHPMQHNPNGP 420 Query: 172 PPAHLPGPPPP----PPPPPHYPVLQRDLYMKAEPPIPHYAAMGQGLVPTDLHHTQQSQM 227 PP + PPPP P PP H+ D Y+ + P +G G+ Sbjct: 421 PPPWMQPPPPPMNQGPHPPGHHGPPPMDQYLGSTP-------VGSGV------------- 460 Query: 228 LHQLLQQHGAELPTHPSKKRKHSESPPSTLNAQMLNGMIKQEPGTVTALPLHPTRAPSPP 287 ++L Q G P PP GM+ P + P P P PP Sbjct: 461 -YRLHQGKGMMPP------------PPM--------GMMPPPPPPPSGQPPPPPSGPLPP 499 Query: 288 WPPQGPLSPGPGSLPLSIARVQTPPW 313 W Q P P S+A PW Sbjct: 500 WQQQQQQPPPPPPPSSSMASSTPLPW 525 >gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapiens] Length = 855 Score = 58.5 bits (140), Expect = 3e-08 Identities = 84/311 (27%), Positives = 112/311 (36%), Gaps = 59/311 (18%) Query: 41 ISAPASSASYSHG------QPAMPGSSGVHHLSPPGGGPSPGRHGPLPPPGYGTPLNCNN 94 +S+PA S + G P+ P G+ L PP P P P +PL + Sbjct: 249 LSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPS 308 Query: 95 NNG--MGAAPKPFPGGT---------GPPIKAEPKAPYAPG---TLPDSPPDSGSEAYSP 140 + AP P P+ P +P AP TLP P S+A + Sbjct: 309 PSAALQSQAPPTLPATPHSSSLTCQLATPLPLAPPSPSAPPSLQTLPSPPATPPSQATT- 367 Query: 141 QQVNEPHLLRTITPETLCHVGVPSRLEHPPPPPAHLPGPPPPPPPPPHYPVLQRDLYMKA 200 + P L T H +PS PP + L PPP PP P LQ A Sbjct: 368 -SLGSPTLQAT-------HSFLPS------PPLSPLATPPPQAPPALALPPLQAPPSPPA 413 Query: 201 EPPIPHYAAMGQGLVPTDLHHTQQSQMLHQLLQQHGAELPTHPSKKRKHSESPPSTLNAQ 260 PP+ A T + +H LLQ A PS + SPP++ Sbjct: 414 SPPLSPLA--------TPSPQAPNALAVH-LLQ---APFSPPPSPPVQAPFSPPASPPVS 461 Query: 261 MLNGMIKQEPGTVTALPLH--------PTRAPSPPWPPQGPLSPGPGSLPLSIARVQTPP 312 Q P ++ A PL P +PS PPQ P P + PL +A+ PP Sbjct: 462 PSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAP--PPLAAPPLQLAK--PPP 517 Query: 313 WHPPGAPSPGL 323 PP +P L Sbjct: 518 QAPPALATPPL 528 Score = 57.4 bits (137), Expect = 7e-08 Identities = 74/271 (27%), Positives = 99/271 (36%), Gaps = 31/271 (11%) Query: 73 PSPGRHGPLPPPGYGTPLNCNNNNGMGAAPKPFPGGTGPPIKAEPKAPYAPGTLPDSPPD 132 PSP P G G + + A P P +GP + P+AP P P Sbjct: 220 PSPAARRR-PSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAP----AHPSQPKP 274 Query: 133 SGSEAYSPQQVNEPH--LLRTITPETLCHVGVPS-----RLEHPPPPPA---------HL 176 G +A P QV P + P + + PS + + PP PA L Sbjct: 275 KGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAALQSQAPPTLPATPHSSSLTCQL 334 Query: 177 PGPPPPPPPPPHYPVLQRDLYMKAEPPIPHYAAMGQGLVPTDLHHTQQSQMLHQLLQQHG 236 P P PP P P + L P P A G H+ L Sbjct: 335 ATPLPLAPPSPSAPPSLQTLPSPPATP-PSQATTSLGSPTLQATHSFLPSPPLSPLATPP 393 Query: 237 AELPTHPSKKRKHSESPPSTLNAQMLNGMIKQEPGTVTALPLHPTRAP--SPPWPP-QGP 293 + P P+ ++PPS + L+ + P AL +H +AP PP PP Q P Sbjct: 394 PQAP--PALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAP 451 Query: 294 LSPGPGSLPLSIARVQTPPWH-PPGAPSPGL 323 SP P S P+S + TPP PP +P L Sbjct: 452 FSP-PASPPVSPS--ATPPSQAPPSLAAPPL 479 Score = 52.0 bits (123), Expect = 3e-06 Identities = 68/285 (23%), Positives = 93/285 (32%), Gaps = 47/285 (16%) Query: 66 LSPPGGGPSPGRHGPLPPPGYGTPLNCNNNNGMGAAPKPFPGGTGPPIKAEPKAPYAPGT 125 L P PSP PL P +P N + PF PP++A P++P Sbjct: 402 LPPLQAPPSPPASPPLSPLATPSP-QAPNALAVHLLQAPFSPPPSPPVQA----PFSPPA 456 Query: 126 LPDSPPDSGSEAYSPQQVNEPHLLRTITPETLCHVGVPSRLEHPPPPPAHLPGPPPPPPP 185 P P + + +P + P L + PP PPA P P PP Sbjct: 457 SPPVSPSATPPSQAPPSLAAPPL------------------QVPPSPPASPPMSPSATPP 498 Query: 186 PPHYPVLQRDLYMKAEPPIPHYAAMGQGLVPTDLHHTQQSQMLHQLLQQHGAELPTHPSK 245 P P L A+PP A+ T Q L + P PS Sbjct: 499 PQAPPPLAAPPLQLAKPPPQAPPALA----------TPPLQALPSPPASFPGQAPFSPSA 548 Query: 246 KRKHS--ESPPSTLNAQMLNGMIKQEPGTVTALPLHPTRAPSPPWPPQGPLSPGPGSLPL 303 S +PP + +++ P + L R P P P P L L Sbjct: 549 SLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGP---RLTL 605 Query: 304 SIARVQTPPWHPPGAPSPGLLQDSDSLSGSYLDPNYQSIKWQPHQ 348 ++A PG P P S +LSG L + S P + Sbjct: 606 ALA---------PGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEE 641 Score = 38.1 bits (87), Expect = 0.047 Identities = 82/355 (23%), Positives = 107/355 (30%), Gaps = 81/355 (22%) Query: 42 SAPASSASYSHGQPAM-PGSSGVHHLSPPGGGPSPG------------RHGPL------- 81 + P SA S PA P +SG +PP SPG R GPL Sbjct: 77 AGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRI 136 Query: 82 ------------------------------PPPGYGTPLNCNNNNGMG---AAPKPFPGG 108 P PG +P + G P+P P Sbjct: 137 SAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSA 196 Query: 109 TGPPIKAEPKAPYAPGTLPDSPPDSGSEAYSP------QQVNEPHLLRTITPETL----- 157 P P+ + + + S + P Q+ L + TP + Sbjct: 197 RPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSG 256 Query: 158 -CHVGVPSRLEHP-PPPPAHLPGPPPPPPPPPHYPVLQRDLYMKAEP-PIPHYAAMGQGL 214 G P HP P P L PP PP + + P P +A Q Sbjct: 257 PSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAALQSQ 316 Query: 215 VPTDLHHTQQSQMLHQLLQQHGAELPTHPS--KKRKHSESPPSTLNAQMLNGM----IKQ 268 P L T S L L P PS + SPP+T +Q + ++ Sbjct: 317 APPTLPATPHSSSLTCQLATPLPLAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQA 376 Query: 269 EPGTVTALPLHPTRAPSPPWPPQGPLSP--GPGSLPLSIARVQTPPWHPPGAPSP 321 + + PL P P P PP L P P S P S PP P PSP Sbjct: 377 THSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPAS------PPLSPLATPSP 425 Score = 34.3 bits (77), Expect = 0.67 Identities = 30/88 (34%), Positives = 36/88 (40%), Gaps = 8/88 (9%) Query: 801 TTQLRQSPLTTGLPGIQPSLLLVTTSLTSSAPGSAVRTLDMCSSHPCPVICCSSPTTNPT 860 + L SPL T P P L + S P S TL P P P T+ Sbjct: 547 SASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASP--TLQAPRRPPTP-----GPDTS-V 598 Query: 861 TGPSLGPSFNPGHVLSPSPSPSTNRSGP 888 +GP L + PG PS SPS+ SGP Sbjct: 599 SGPRLTLALAPGPPPPPSRSPSSTLSGP 626 Score = 32.3 bits (72), Expect = 2.6 Identities = 36/129 (27%), Positives = 49/129 (37%), Gaps = 29/129 (22%) Query: 29 SKEDASDLCFPDISAPASSASYSHGQPAM--PGSSGVHHLSPPGGG------PSPGRHGP 80 S+ +S L PD++ +SSA+ + + G G SPP P+ GP Sbjct: 616 SRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGP 675 Query: 81 LPPPGYGTPLNCNNNNGMGAAPKPFPGGTGP----------PIKAEPKAPYAPGTLP--D 128 PP + G AP P+P TGP + A APG L Sbjct: 676 APPLAF---------RGAPGAPLPWPPATGPGSADGLCTIYETEGPESATPAPGALDPGP 726 Query: 129 SPPDSGSEA 137 SP SG +A Sbjct: 727 SPGTSGGKA 735 >gi|5032069 splicing factor 3b, subunit 4 [Homo sapiens] Length = 424 Score = 58.5 bits (140), Expect = 3e-08 Identities = 68/251 (27%), Positives = 82/251 (32%), Gaps = 59/251 (23%) Query: 68 PPGGGPSP---GRHGPLPPPGYGTPLNCNNNNGMGAAPKPFPGGTGPPIK-AEPKAPYAP 123 PP P+P LPPPG P G P P PG P I A P P P Sbjct: 216 PPPSAPNPVVSSLGSGLPPPGMPPP-------GSFPPPVPPPGALPPGIPPAMPPPPMPP 268 Query: 124 GTLPDSPPDSGSEA--YSPQQVNEPHLLRTITPETLCHVGV---------PSRLEHPPPP 172 G PP +G+ + + PH P + H G+ P L HP Sbjct: 269 GAAGHGPPSAGTPGAGHPGHGHSHPH---PFPPGGMPHPGMSQMQLAHHGPHGLGHPHAG 325 Query: 173 PAHLPGPPPPPPPPPHYPVLQRDLYMKAEPPIPHYAAMGQGLVPTDLHHTQQSQMLHQLL 232 P G PPP PPP +PH G+ P Sbjct: 326 PPGSGGQPPPRPPPG----------------MPHPGPPPMGMPPRGPPFGSP-------- 361 Query: 233 QQHGAELPTHPSKKRKHSESPPSTLNAQMLNGMIKQEPGTVTALPLHPTR-APSPPWPPQ 291 H +P H + PP + G + P PL P R P PP PP+ Sbjct: 362 MGHPGPMPPHGMR------GPPPLMPPHGYTGPPRPPPYGYQRGPLPPPRPTPRPPVPPR 415 Query: 292 GPLSPGPGSLP 302 GPL G LP Sbjct: 416 GPLR---GPLP 423 Score = 55.1 bits (131), Expect = 4e-07 Identities = 57/170 (33%), Positives = 63/170 (37%), Gaps = 38/170 (22%) Query: 44 PASSASYSHGQPAM-------PGSSGVH-HLSPPGGGPSPG-------RHGP--LPPPGY 86 P + HG P+ PG H H PPGG P PG HGP L P Sbjct: 265 PMPPGAAGHGPPSAGTPGAGHPGHGHSHPHPFPPGGMPHPGMSQMQLAHHGPHGLGHPHA 324 Query: 87 GTPLNCNNNNGMGAAPKPFPGGTGPPIKAEPKAPYAPGTLPDSPPDSGSEAYSPQQVNEP 146 G P G G P P P PP P P P +P P GS P + P Sbjct: 325 GPP-------GSGGQPPPRP----PPGMPHPGPP--PMGMPPRGPPFGSPMGHPGPM-PP 370 Query: 147 HLLRTITPETLCH--VGVPSRLEHPPPPPAHLPGPPPPPPPPPHYPVLQR 194 H +R P H G P PPP + GP PPP P P PV R Sbjct: 371 HGMRGPPPLMPPHGYTGPPR-----PPPYGYQRGPLPPPRPTPRPPVPPR 415 Score = 46.6 bits (109), Expect = 1e-04 Identities = 54/183 (29%), Positives = 59/183 (32%), Gaps = 33/183 (18%) Query: 163 PSRLEHPPPPPAHLP-GPPPPPPPPPHYPVLQRDLYMKAEPPIPHYAAMGQG----LVPT 217 P P PPP LP G PP PPPP P A P + G P Sbjct: 240 PGSFPPPVPPPGALPPGIPPAMPPPPMPPGAAGHGPPSAGTPGAGHPGHGHSHPHPFPPG 299 Query: 218 DLHHTQQSQML------HQLLQQH------GAELPTHPSKKRKHSESPPSTLNAQMLNGM 265 + H SQM H L H G + P P H PP GM Sbjct: 300 GMPHPGMSQMQLAHHGPHGLGHPHAGPPGSGGQPPPRPPPGMPHPGPPPM--------GM 351 Query: 266 IKQEP------GTVTALPLHPTRAPSPPWPPQGPLSPGPGSLPLSIARVQTPPWHP-PGA 318 + P G +P H R P P PP G P P P R PP P P Sbjct: 352 PPRGPPFGSPMGHPGPMPPHGMRGPPPLMPPHGYTGP-PRPPPYGYQRGPLPPPRPTPRP 410 Query: 319 PSP 321 P P Sbjct: 411 PVP 413 Score = 35.0 bits (79), Expect = 0.39 Identities = 19/42 (45%), Positives = 20/42 (47%), Gaps = 3/42 (7%) Query: 284 PSPPWPPQG---PLSPGPGSLPLSIARVQTPPWHPPGAPSPG 322 P P PP G P P PG+LP I PP PPGA G Sbjct: 233 PPPGMPPPGSFPPPVPPPGALPPGIPPAMPPPPMPPGAAGHG 274 >gi|112382226 atrophin-1 like protein isoform b [Homo sapiens] Length = 1012 Score = 58.5 bits (140), Expect = 3e-08 Identities = 76/256 (29%), Positives = 95/256 (37%), Gaps = 46/256 (17%) Query: 83 PPGYGTPLNCNNNNGMGAAPKPFPGGTGPPIKAEPKAPYAPGTLPDSP--PDSGSEAYSP 140 PP P G+ AP P GT P+ P PG P + P GS S Sbjct: 184 PPALQAP------TGVTPAPSSAPPGT-------PQLP-TPGPTPSATAVPPQGSPTAS- 228 Query: 141 QQVNEPHLLRTITPETLCHVGVPSRLEHPPPPPAHLPGPPPPPPPPPHYPVLQRDLYMKA 200 Q N+P P T H+ L HP PP+ P PPP P PH P LQ Sbjct: 229 QAPNQPQAPTAPVPHT--HIQQAPAL-HPQRPPS----PHPPPHPSPH-PPLQPLTGSAG 280 Query: 201 EPPIPHYA---AMGQGLVPTDLHHTQQSQMLHQLLQQHGAELPTHPSKKRKHSESPPSTL 257 +P P +A GQG P H Q LLQ G P + ++P T Sbjct: 281 QPSAPSHAQPPLHGQG--PPGPHSLQAG----PLLQHPGPPQPFGLPPQASQGQAPLGTS 334 Query: 258 NAQMLNGMIKQEPGTVTALPLHPTRAPSPPWPPQGPLSPGPGSLPLSIARVQTPPWHP-P 316 A P T LP + S P + PL P P ++P ++ PP P P Sbjct: 335 PAAAY-------PHTSLQLPASQSALQSQQPPREQPLPPAPLAMP----HIKPPPTTPIP 383 Query: 317 GAPSPGLLQDSDSLSG 332 P+P + LSG Sbjct: 384 QLPAPQAHKHPPHLSG 399 Score = 43.5 bits (101), Expect = 0.001 Identities = 55/204 (26%), Positives = 69/204 (33%), Gaps = 37/204 (18%) Query: 129 SPPDSGSEAYSPQQVNEPHLLRTITPETLCHVGVPSRLEHPPPPPAHLPGPPPPPP---- 184 SP D+ S++ S Q +L+ P GV PP LP P P P Sbjct: 163 SPQDNESDSDSSAQ---QQMLQAQPPALQAPTGVTPAPSSAPPGTPQLPTPGPTPSATAV 219 Query: 185 PPPHYPVLQRDLYMKAEP--PIPHYAAMGQGLVPTDLHHTQQSQMLHQLLQQHGAELPTH 242 PP P + P P+PH H QQ+ LH + P H Sbjct: 220 PPQGSPTASQAPNQPQAPTAPVPH-------------THIQQAPALHP-QRPPSPHPPPH 265 Query: 243 PSKKRKHSESPPSTLNAQMLNGMIKQEPGTVTALPLHPTRAPSPPWPPQGPL-----SPG 297 PS H P T +A + +P PLH P P GPL P Sbjct: 266 PS---PHPPLQPLTGSAGQPSAPSHAQP------PLHGQGPPGPHSLQAGPLLQHPGPPQ 316 Query: 298 PGSLPLSIARVQTPPWHPPGAPSP 321 P LP ++ Q P P A P Sbjct: 317 PFGLPPQASQGQAPLGTSPAAAYP 340 Score = 43.1 bits (100), Expect = 0.001 Identities = 59/240 (24%), Positives = 83/240 (34%), Gaps = 31/240 (12%) Query: 34 SDLCFPDISAPASSASYSHGQPAMPGSSGVHHLSPPGGGPSPGRHGPL----PPPGYG-T 88 + L P + S QP P + H+ PP P P P PP G + Sbjct: 342 TSLQLPASQSALQSQQPPREQPLPPAPLAMPHIKPPPTTPIPQLPAPQAHKHPPHLSGPS 401 Query: 89 PLNCNNNNGMGAAPKPF--------PGGTGPPIKAEPKAPYAPGTLPDSPPDSGSEAYSP 140 P + N N A KP P PP++ P++ P + P + S+ P Sbjct: 402 PFSMNANLPPPPALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPGLTQSQNLPP 461 Query: 141 QQVNEPHL-LRTITPETLCHVGVPSRLEHPPPPPAHLPGPPPP--PPPPPHYPVLQRDLY 197 + P L + P+ P +HP +PG PPP PP P Sbjct: 462 PPASHPPTGLHQVAPQ-------PPFAQHP-----FVPGGPPPITPPTCPSTSTPPAGPG 509 Query: 198 MKAEPPIPHYAAMGQGLVPTDLHHTQQSQMLHQLLQQHGAELPTHPSKKRKHSESPPSTL 257 A+PP AA G + Q+ + L AE P P + S SP T+ Sbjct: 510 TSAQPPCSGAAASGGSIAGGSSCPLPTVQIKEEALDD--AEEPESPPPPPR-SPSPEPTV 566 Score = 37.0 bits (84), Expect = 0.10 Identities = 56/209 (26%), Positives = 73/209 (34%), Gaps = 63/209 (30%) Query: 39 PDISAPASSASYSHGQPAMPGSSGVHHLSPP--GGGPSPGRH----GPL-----PPPGYG 87 P P + S GQP+ P H PP G GP PG H GPL PP +G Sbjct: 266 PSPHPPLQPLTGSAGQPSAPS-----HAQPPLHGQGP-PGPHSLQAGPLLQHPGPPQPFG 319 Query: 88 TPLNCNNNNG-MGAAPKPFPGGTGPPIKAEPKA------------PYAPGTLPDSPPDSG 134 P + +G +P T + A A P AP +P P Sbjct: 320 LPPQASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPREQPLPPAPLAMPHIKPPPT 379 Query: 135 S---EAYSPQQVNEPHLLRTITPETL-CHVGVPSRLE--------HPP---PPPAHL--- 176 + + +PQ P L +P ++ ++ P L+ HPP PPP L Sbjct: 380 TPIPQLPAPQAHKHPPHLSGPSPFSMNANLPPPPALKPLSSLSTHHPPSAHPPPLQLMPQ 439 Query: 177 -------PGPPP--------PPPPPPHYP 190 P PP PPPP H P Sbjct: 440 SQPLPSSPAQPPGLTQSQNLPPPPASHPP 468 Score = 33.5 bits (75), Expect = 1.1 Identities = 64/279 (22%), Positives = 91/279 (32%), Gaps = 35/279 (12%) Query: 51 SHGQPAMPGSSGVHHLSPPGGG-PSPGRHGPLPPPGYGTPLNCNNNNGMGAAPKPFPGGT 109 S QP PG + +L PP P G H P P + A PF G Sbjct: 446 SPAQP--PGLTQSQNLPPPPASHPPTGLHQVAPQPPF--------------AQHPFVPGG 489 Query: 110 GPPIK-----AEPKAPYAPGTLPDSPPDSGSEAYSPQQVNE---PHLLRTITPETLCHVG 161 PPI + P PGT PP SG+ A P I E L Sbjct: 490 PPPITPPTCPSTSTPPAGPGTSAQ-PPCSGAAASGGSIAGGSSCPLPTVQIKEEALDDAE 548 Query: 162 VPSRLEHPPPPPAHLPGPPPPPPPPPHYPVLQRDLYMKAEPPIPHYAAMGQGLVPTDLHH 221 P E PPPPP P P P P + Y + A +P L Sbjct: 549 EP---ESPPPPP-RSPSPEPTVVDTPSHASQSARFYKHLDRGYNSCARTDLYFMP--LAG 602 Query: 222 TQQSQMLHQLLQQHGAELPTHPSKKRKHSESPPSTLNAQMLNGMIKQEPGTVTALPLHPT 281 ++ ++ + +++ E ++R+ + + + E + H Sbjct: 603 SKLAKKREEAIEKAKREAEQKAREEREREKEKEKERERERERER-EAERAAKASSSAHEG 661 Query: 282 RAPSPPWPPQGPLSPGPGSLPLSIARVQTPPWHPPGAPS 320 R P G + P P +IA V PP+ P P+ Sbjct: 662 RLSDPQLSGPGHMRPSFEPPPTTIAAV--PPYIGPDTPA 698 >gi|112382224 atrophin-1 like protein isoform a [Homo sapiens] Length = 1566 Score = 58.5 bits (140), Expect = 3e-08 Identities = 76/256 (29%), Positives = 95/256 (37%), Gaps = 46/256 (17%) Query: 83 PPGYGTPLNCNNNNGMGAAPKPFPGGTGPPIKAEPKAPYAPGTLPDSP--PDSGSEAYSP 140 PP P G+ AP P GT P+ P PG P + P GS S Sbjct: 738 PPALQAP------TGVTPAPSSAPPGT-------PQLP-TPGPTPSATAVPPQGSPTAS- 782 Query: 141 QQVNEPHLLRTITPETLCHVGVPSRLEHPPPPPAHLPGPPPPPPPPPHYPVLQRDLYMKA 200 Q N+P P T H+ L HP PP+ P PPP P PH P LQ Sbjct: 783 QAPNQPQAPTAPVPHT--HIQQAPAL-HPQRPPS----PHPPPHPSPH-PPLQPLTGSAG 834 Query: 201 EPPIPHYA---AMGQGLVPTDLHHTQQSQMLHQLLQQHGAELPTHPSKKRKHSESPPSTL 257 +P P +A GQG P H Q LLQ G P + ++P T Sbjct: 835 QPSAPSHAQPPLHGQG--PPGPHSLQAG----PLLQHPGPPQPFGLPPQASQGQAPLGTS 888 Query: 258 NAQMLNGMIKQEPGTVTALPLHPTRAPSPPWPPQGPLSPGPGSLPLSIARVQTPPWHP-P 316 A P T LP + S P + PL P P ++P ++ PP P P Sbjct: 889 PAAAY-------PHTSLQLPASQSALQSQQPPREQPLPPAPLAMP----HIKPPPTTPIP 937 Query: 317 GAPSPGLLQDSDSLSG 332 P+P + LSG Sbjct: 938 QLPAPQAHKHPPHLSG 953 Score = 43.5 bits (101), Expect = 0.001 Identities = 55/204 (26%), Positives = 69/204 (33%), Gaps = 37/204 (18%) Query: 129 SPPDSGSEAYSPQQVNEPHLLRTITPETLCHVGVPSRLEHPPPPPAHLPGPPPPPP---- 184 SP D+ S++ S Q +L+ P GV PP LP P P P Sbjct: 717 SPQDNESDSDSSAQ---QQMLQAQPPALQAPTGVTPAPSSAPPGTPQLPTPGPTPSATAV 773 Query: 185 PPPHYPVLQRDLYMKAEP--PIPHYAAMGQGLVPTDLHHTQQSQMLHQLLQQHGAELPTH 242 PP P + P P+PH H QQ+ LH + P H Sbjct: 774 PPQGSPTASQAPNQPQAPTAPVPH-------------THIQQAPALHP-QRPPSPHPPPH 819 Query: 243 PSKKRKHSESPPSTLNAQMLNGMIKQEPGTVTALPLHPTRAPSPPWPPQGPL-----SPG 297 PS H P T +A + +P PLH P P GPL P Sbjct: 820 PS---PHPPLQPLTGSAGQPSAPSHAQP------PLHGQGPPGPHSLQAGPLLQHPGPPQ 870 Query: 298 PGSLPLSIARVQTPPWHPPGAPSP 321 P LP ++ Q P P A P Sbjct: 871 PFGLPPQASQGQAPLGTSPAAAYP 894 Score = 43.1 bits (100), Expect = 0.001 Identities = 59/240 (24%), Positives = 83/240 (34%), Gaps = 31/240 (12%) Query: 34 SDLCFPDISAPASSASYSHGQPAMPGSSGVHHLSPPGGGPSPGRHGPL----PPPGYG-T 88 + L P + S QP P + H+ PP P P P PP G + Sbjct: 896 TSLQLPASQSALQSQQPPREQPLPPAPLAMPHIKPPPTTPIPQLPAPQAHKHPPHLSGPS 955 Query: 89 PLNCNNNNGMGAAPKPF--------PGGTGPPIKAEPKAPYAPGTLPDSPPDSGSEAYSP 140 P + N N A KP P PP++ P++ P + P + S+ P Sbjct: 956 PFSMNANLPPPPALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPGLTQSQNLPP 1015 Query: 141 QQVNEPHL-LRTITPETLCHVGVPSRLEHPPPPPAHLPGPPPP--PPPPPHYPVLQRDLY 197 + P L + P+ P +HP +PG PPP PP P Sbjct: 1016 PPASHPPTGLHQVAPQ-------PPFAQHP-----FVPGGPPPITPPTCPSTSTPPAGPG 1063 Query: 198 MKAEPPIPHYAAMGQGLVPTDLHHTQQSQMLHQLLQQHGAELPTHPSKKRKHSESPPSTL 257 A+PP AA G + Q+ + L AE P P + S SP T+ Sbjct: 1064 TSAQPPCSGAAASGGSIAGGSSCPLPTVQIKEEALDD--AEEPESPPPPPR-SPSPEPTV 1120 Score = 37.0 bits (84), Expect = 0.10 Identities = 56/209 (26%), Positives = 73/209 (34%), Gaps = 63/209 (30%) Query: 39 PDISAPASSASYSHGQPAMPGSSGVHHLSPP--GGGPSPGRH----GPL-----PPPGYG 87 P P + S GQP+ P H PP G GP PG H GPL PP +G Sbjct: 820 PSPHPPLQPLTGSAGQPSAPS-----HAQPPLHGQGP-PGPHSLQAGPLLQHPGPPQPFG 873 Query: 88 TPLNCNNNNG-MGAAPKPFPGGTGPPIKAEPKA------------PYAPGTLPDSPPDSG 134 P + +G +P T + A A P AP +P P Sbjct: 874 LPPQASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPREQPLPPAPLAMPHIKPPPT 933 Query: 135 S---EAYSPQQVNEPHLLRTITPETL-CHVGVPSRLE--------HPP---PPPAHL--- 176 + + +PQ P L +P ++ ++ P L+ HPP PPP L Sbjct: 934 TPIPQLPAPQAHKHPPHLSGPSPFSMNANLPPPPALKPLSSLSTHHPPSAHPPPLQLMPQ 993 Query: 177 -------PGPPP--------PPPPPPHYP 190 P PP PPPP H P Sbjct: 994 SQPLPSSPAQPPGLTQSQNLPPPPASHPP 1022 Score = 33.5 bits (75), Expect = 1.1 Identities = 64/279 (22%), Positives = 91/279 (32%), Gaps = 35/279 (12%) Query: 51 SHGQPAMPGSSGVHHLSPPGGG-PSPGRHGPLPPPGYGTPLNCNNNNGMGAAPKPFPGGT 109 S QP PG + +L PP P G H P P + A PF G Sbjct: 1000 SPAQP--PGLTQSQNLPPPPASHPPTGLHQVAPQPPF--------------AQHPFVPGG 1043 Query: 110 GPPIK-----AEPKAPYAPGTLPDSPPDSGSEAYSPQQVNE---PHLLRTITPETLCHVG 161 PPI + P PGT PP SG+ A P I E L Sbjct: 1044 PPPITPPTCPSTSTPPAGPGTSAQ-PPCSGAAASGGSIAGGSSCPLPTVQIKEEALDDAE 1102 Query: 162 VPSRLEHPPPPPAHLPGPPPPPPPPPHYPVLQRDLYMKAEPPIPHYAAMGQGLVPTDLHH 221 P E PPPPP P P P P + Y + A +P L Sbjct: 1103 EP---ESPPPPP-RSPSPEPTVVDTPSHASQSARFYKHLDRGYNSCARTDLYFMP--LAG 1156 Query: 222 TQQSQMLHQLLQQHGAELPTHPSKKRKHSESPPSTLNAQMLNGMIKQEPGTVTALPLHPT 281 ++ ++ + +++ E ++R+ + + + E + H Sbjct: 1157 SKLAKKREEAIEKAKREAEQKAREEREREKEKEKERERERERER-EAERAAKASSSAHEG 1215 Query: 282 RAPSPPWPPQGPLSPGPGSLPLSIARVQTPPWHPPGAPS 320 R P G + P P +IA V PP+ P P+ Sbjct: 1216 RLSDPQLSGPGHMRPSFEPPPTTIAAV--PPYIGPDTPA 1252 >gi|112382216 atrophin-1 like protein isoform a [Homo sapiens] Length = 1566 Score = 58.5 bits (140), Expect = 3e-08 Identities = 76/256 (29%), Positives = 95/256 (37%), Gaps = 46/256 (17%) Query: 83 PPGYGTPLNCNNNNGMGAAPKPFPGGTGPPIKAEPKAPYAPGTLPDSP--PDSGSEAYSP 140 PP P G+ AP P GT P+ P PG P + P GS S Sbjct: 738 PPALQAP------TGVTPAPSSAPPGT-------PQLP-TPGPTPSATAVPPQGSPTAS- 782 Query: 141 QQVNEPHLLRTITPETLCHVGVPSRLEHPPPPPAHLPGPPPPPPPPPHYPVLQRDLYMKA 200 Q N+P P T H+ L HP PP+ P PPP P PH P LQ Sbjct: 783 QAPNQPQAPTAPVPHT--HIQQAPAL-HPQRPPS----PHPPPHPSPH-PPLQPLTGSAG 834 Query: 201 EPPIPHYA---AMGQGLVPTDLHHTQQSQMLHQLLQQHGAELPTHPSKKRKHSESPPSTL 257 +P P +A GQG P H Q LLQ G P + ++P T Sbjct: 835 QPSAPSHAQPPLHGQG--PPGPHSLQAG----PLLQHPGPPQPFGLPPQASQGQAPLGTS 888 Query: 258 NAQMLNGMIKQEPGTVTALPLHPTRAPSPPWPPQGPLSPGPGSLPLSIARVQTPPWHP-P 316 A P T LP + S P + PL P P ++P ++ PP P P Sbjct: 889 PAAAY-------PHTSLQLPASQSALQSQQPPREQPLPPAPLAMP----HIKPPPTTPIP 937 Query: 317 GAPSPGLLQDSDSLSG 332 P+P + LSG Sbjct: 938 QLPAPQAHKHPPHLSG 953 Score = 43.5 bits (101), Expect = 0.001 Identities = 55/204 (26%), Positives = 69/204 (33%), Gaps = 37/204 (18%) Query: 129 SPPDSGSEAYSPQQVNEPHLLRTITPETLCHVGVPSRLEHPPPPPAHLPGPPPPPP---- 184 SP D+ S++ S Q +L+ P GV PP LP P P P Sbjct: 717 SPQDNESDSDSSAQ---QQMLQAQPPALQAPTGVTPAPSSAPPGTPQLPTPGPTPSATAV 773 Query: 185 PPPHYPVLQRDLYMKAEP--PIPHYAAMGQGLVPTDLHHTQQSQMLHQLLQQHGAELPTH 242 PP P + P P+PH H QQ+ LH + P H Sbjct: 774 PPQGSPTASQAPNQPQAPTAPVPH-------------THIQQAPALHP-QRPPSPHPPPH 819 Query: 243 PSKKRKHSESPPSTLNAQMLNGMIKQEPGTVTALPLHPTRAPSPPWPPQGPL-----SPG 297 PS H P T +A + +P PLH P P GPL P Sbjct: 820 PS---PHPPLQPLTGSAGQPSAPSHAQP------PLHGQGPPGPHSLQAGPLLQHPGPPQ 870 Query: 298 PGSLPLSIARVQTPPWHPPGAPSP 321 P LP ++ Q P P A P Sbjct: 871 PFGLPPQASQGQAPLGTSPAAAYP 894 Score = 43.1 bits (100), Expect = 0.001 Identities = 59/240 (24%), Positives = 83/240 (34%), Gaps = 31/240 (12%) Query: 34 SDLCFPDISAPASSASYSHGQPAMPGSSGVHHLSPPGGGPSPGRHGPL----PPPGYG-T 88 + L P + S QP P + H+ PP P P P PP G + Sbjct: 896 TSLQLPASQSALQSQQPPREQPLPPAPLAMPHIKPPPTTPIPQLPAPQAHKHPPHLSGPS 955 Query: 89 PLNCNNNNGMGAAPKPF--------PGGTGPPIKAEPKAPYAPGTLPDSPPDSGSEAYSP 140 P + N N A KP P PP++ P++ P + P + S+ P Sbjct: 956 PFSMNANLPPPPALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPGLTQSQNLPP 1015 Query: 141 QQVNEPHL-LRTITPETLCHVGVPSRLEHPPPPPAHLPGPPPP--PPPPPHYPVLQRDLY 197 + P L + P+ P +HP +PG PPP PP P Sbjct: 1016 PPASHPPTGLHQVAPQ-------PPFAQHP-----FVPGGPPPITPPTCPSTSTPPAGPG 1063 Query: 198 MKAEPPIPHYAAMGQGLVPTDLHHTQQSQMLHQLLQQHGAELPTHPSKKRKHSESPPSTL 257 A+PP AA G + Q+ + L AE P P + S SP T+ Sbjct: 1064 TSAQPPCSGAAASGGSIAGGSSCPLPTVQIKEEALDD--AEEPESPPPPPR-SPSPEPTV 1120 Score = 37.0 bits (84), Expect = 0.10 Identities = 56/209 (26%), Positives = 73/209 (34%), Gaps = 63/209 (30%) Query: 39 PDISAPASSASYSHGQPAMPGSSGVHHLSPP--GGGPSPGRH----GPL-----PPPGYG 87 P P + S GQP+ P H PP G GP PG H GPL PP +G Sbjct: 820 PSPHPPLQPLTGSAGQPSAPS-----HAQPPLHGQGP-PGPHSLQAGPLLQHPGPPQPFG 873 Query: 88 TPLNCNNNNG-MGAAPKPFPGGTGPPIKAEPKA------------PYAPGTLPDSPPDSG 134 P + +G +P T + A A P AP +P P Sbjct: 874 LPPQASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPREQPLPPAPLAMPHIKPPPT 933 Query: 135 S---EAYSPQQVNEPHLLRTITPETL-CHVGVPSRLE--------HPP---PPPAHL--- 176 + + +PQ P L +P ++ ++ P L+ HPP PPP L Sbjct: 934 TPIPQLPAPQAHKHPPHLSGPSPFSMNANLPPPPALKPLSSLSTHHPPSAHPPPLQLMPQ 993 Query: 177 -------PGPPP--------PPPPPPHYP 190 P PP PPPP H P Sbjct: 994 SQPLPSSPAQPPGLTQSQNLPPPPASHPP 1022 Score = 33.5 bits (75), Expect = 1.1 Identities = 64/279 (22%), Positives = 91/279 (32%), Gaps = 35/279 (12%) Query: 51 SHGQPAMPGSSGVHHLSPPGGG-PSPGRHGPLPPPGYGTPLNCNNNNGMGAAPKPFPGGT 109 S QP PG + +L PP P G H P P + A PF G Sbjct: 1000 SPAQP--PGLTQSQNLPPPPASHPPTGLHQVAPQPPF--------------AQHPFVPGG 1043 Query: 110 GPPIK-----AEPKAPYAPGTLPDSPPDSGSEAYSPQQVNE---PHLLRTITPETLCHVG 161 PPI + P PGT PP SG+ A P I E L Sbjct: 1044 PPPITPPTCPSTSTPPAGPGTSAQ-PPCSGAAASGGSIAGGSSCPLPTVQIKEEALDDAE 1102 Query: 162 VPSRLEHPPPPPAHLPGPPPPPPPPPHYPVLQRDLYMKAEPPIPHYAAMGQGLVPTDLHH 221 P E PPPPP P P P P + Y + A +P L Sbjct: 1103 EP---ESPPPPP-RSPSPEPTVVDTPSHASQSARFYKHLDRGYNSCARTDLYFMP--LAG 1156 Query: 222 TQQSQMLHQLLQQHGAELPTHPSKKRKHSESPPSTLNAQMLNGMIKQEPGTVTALPLHPT 281 ++ ++ + +++ E ++R+ + + + E + H Sbjct: 1157 SKLAKKREEAIEKAKREAEQKAREEREREKEKEKERERERERER-EAERAAKASSSAHEG 1215 Query: 282 RAPSPPWPPQGPLSPGPGSLPLSIARVQTPPWHPPGAPS 320 R P G + P P +IA V PP+ P P+ Sbjct: 1216 RLSDPQLSGPGHMRPSFEPPPTTIAAV--PPYIGPDTPA 1252 >gi|24308073 protein tyrosine phosphatase, non-receptor type 23 [Homo sapiens] Length = 1636 Score = 58.2 bits (139), Expect = 4e-08 Identities = 90/362 (24%), Positives = 114/362 (31%), Gaps = 112/362 (30%) Query: 68 PPGGGPS---PGRH---GPLPPPGYGTPLNCNNNNGMGAAPKPFPGGTGPPIKAEPKAPY 121 PP PS PG H GPLPP Y P G P P GP + P Sbjct: 772 PPSPFPSSTGPGPHYLSGPLPPGTYSGPTQLIQPRAPG--PHAMPVAPGPALYPAPAYTP 829 Query: 122 APGTLPDS-----------------PPDSGSEAYSPQQVNEPHLLRTITPETLCHVGVPS 164 G +P S PP +G + P Q + P L + P T + + Sbjct: 830 ELGLVPRSSPQHGVVSSPYVGVGPAPPVAGLPSAPPPQFSGPELAMAVRPATTTVDSIQA 889 Query: 165 RL-EHPPPPPAHLPGPPPP--PPPPPHYPVLQRDLYMKAEPPIP---HYAA--------- 209 + H P P P PPPP P PPP A+ PIP H+++ Sbjct: 890 PIPSHTAPRPNPTPAPPPPCFPVPPPQPLPTPYTYPAGAKQPIPAQHHFSSGIPAGFPAP 949 Query: 210 -MGQGLVPTDLHHTQQS------------QMLHQLLQQHGAELPTHPSKKRKHSESP--- 253 +G P H Q+ Q H Q LP P ++ P Sbjct: 950 RIGPQPQPHPQPHPSQAFGPQPPQQPLPLQHPHLFPPQAPGLLP--PQSPYPYAPQPGVL 1007 Query: 254 ---PSTLNAQMLNGMIKQEPGTVTALPLH----PTRAPSPPWPPQGPL------------ 294 P L+ Q+ G Q+P LP H P +P PP PP PL Sbjct: 1008 GQPPPPLHTQLYPGPA-QDP-----LPAHSGALPFPSPGPPQPPHPPLAYGPAPSTRPMG 1061 Query: 295 -----------------------------SPGPGSLPLSIARVQTPPWHPPGAPSPGLLQ 325 SPGPG +P + PP GA + LL Sbjct: 1062 PQAAPLTIRGPSSAGQSTPSPHLVPSPAPSPGPGPVPPRPPAAEPPPCLRRGAAAADLLS 1121 Query: 326 DS 327 S Sbjct: 1122 SS 1123 Score = 44.7 bits (104), Expect = 5e-04 Identities = 47/143 (32%), Positives = 57/143 (39%), Gaps = 27/143 (18%) Query: 57 MPGSSGVHHLSPPG--GGPSPGRHGPLPPPGYGTPLNCNNNNGMGAAPKPFPGGTGPPIK 114 +P S + PG G P P H L P PL ++ GA P P PG PP Sbjct: 992 LPPQSPYPYAPQPGVLGQPPPPLHTQLYPGPAQDPLPAHS----GALPFPSPGPPQPP-- 1045 Query: 115 AEPKAPYAPGTLPDSPPDSGSEAYSPQQVNEPHLLRTITPETLCHVGVPSRLEHPPPPPA 174 P A G P + P G +A +P + P TP P + P P P Sbjct: 1046 ---HPPLAYGPAPSTRP-MGPQA-APLTIRGPSSAGQSTPS-------PHLVPSPAPSPG 1093 Query: 175 HLPGPPPPPPP---PPHYPVLQR 194 PGP PP PP PP P L+R Sbjct: 1094 --PGPVPPRPPAAEPP--PCLRR 1112 Score = 35.0 bits (79), Expect = 0.39 Identities = 25/75 (33%), Positives = 31/75 (41%), Gaps = 11/75 (14%) Query: 106 PGGTGPPIKAEPKAPYAPGTLPDSPPDSGSEAYSPQQVNEPHLLRTITPETLCHVGVPSR 165 PGG P+ + P PG P S P+S +P + P L + PE P Sbjct: 1510 PGGLESPVASLPGPAEPPGLPPASLPES-----TPIPSSSPPPLSSPLPE------APQP 1558 Query: 166 LEHPPPPPAHLPGPP 180 E PP P A GPP Sbjct: 1559 KEEPPVPEAPSSGPP 1573 Score = 33.9 bits (76), Expect = 0.88 Identities = 30/94 (31%), Positives = 37/94 (39%), Gaps = 18/94 (19%) Query: 66 LSPPGGGPSP--GRHGPLPPPGYGTPLNCNNNNGMGAAPKPF--PGGTGPPIKAEPKAPY 121 + PPGG SP GP PPG + ++P P P P K EP P Sbjct: 1507 IRPPGGLESPVASLPGPAEPPGLPPASLPESTPIPSSSPPPLSSPLPEAPQPKEEPPVPE 1566 Query: 122 APGTLPDSPPDSGSEAYSPQQVNEPHLLRTITPE 155 AP + PP S E LL ++TPE Sbjct: 1567 APSS---GPPSSSLE-----------LLASLTPE 1586 Score = 33.5 bits (75), Expect = 1.1 Identities = 20/52 (38%), Positives = 23/52 (44%), Gaps = 2/52 (3%) Query: 162 VPSRLEHPPPPPAHLPGPPPPPP--PPPHYPVLQRDLYMKAEPPIPHYAAMG 211 +P E P PPA LP P P PPP L K EPP+P + G Sbjct: 1520 LPGPAEPPGLPPASLPESTPIPSSSPPPLSSPLPEAPQPKEEPPVPEAPSSG 1571 >gi|21237805 SWI/SNF-related matrix-associated actin-dependent regulator of chromatin c2 isoform a [Homo sapiens] Length = 1214 Score = 58.2 bits (139), Expect = 4e-08 Identities = 79/301 (26%), Positives = 94/301 (31%), Gaps = 91/301 (30%) Query: 55 PAMPGSSGVHHLSPPGGGPSPGRHGPLPPPGYGTPLNCNNNNGMGAAPKPF--------P 106 PA+P G + P G P HG P P G GA P Sbjct: 963 PALP--PGSQPIPPTGAAGPPAVHGLAVAPASVVPAPA----GSGAPPGSLGPSEQIGQA 1016 Query: 107 GGTGPPIKAEPKAPYAPGTLPDSPPDSGSEAYSP--QQVNEPHLLRTITPETLCHVGVPS 164 G T P + +P PG +P P G SP Q P ++ P + H GV Sbjct: 1017 GSTAGPQQQQPAGAPQPGAVPPGVPPPGPHGPSPFPNQQTPPSMMPGAVPGS-GHPGVAG 1075 Query: 165 RLEHPPPPPAHLPGPPPPPPPPPHYPVLQRDLYMKAEPPIPHYAAMGQGL-----VPTDL 219 P LP PPPPPPP P I + ++ + P +L Sbjct: 1076 NA------PLGLPFGMPPPPPPP-------------APSIIPFGSLADSISINLPAPPNL 1116 Query: 220 HHTQQSQMLHQLLQQHGAELPTHPSKKRKHSESPPSTLNAQMLNGMIKQEPGTVTALPLH 279 H H LP P PP L M N PLH Sbjct: 1117 HG-------------HHHHLPFAPGTL------PPPNLPVSMAN-------------PLH 1144 Query: 280 PTRAPSPPWPPQGPLSPGPGSL----PLSIARVQ--------------TPPWHPPGAPSP 321 P + P PL PG GS P +A VQ TP P APSP Sbjct: 1145 PNLPATTTMPSSLPLGPGLGSAAAQSPAIVAAVQGNLLPSASPLPDPGTPLPPDPTAPSP 1204 Query: 322 G 322 G Sbjct: 1205 G 1205 Score = 43.9 bits (102), Expect = 9e-04 Identities = 56/198 (28%), Positives = 69/198 (34%), Gaps = 56/198 (28%) Query: 41 ISAPASSASYSHGQPAMPGSSGVHHLSPPGGGPSPGRHGPLPPPGYGTPLNC-------N 93 I S+A QPA G + P G P PG HGP P P TP + + Sbjct: 1013 IGQAGSTAGPQQQQPAGAPQPG----AVPPGVPPPGPHGPSPFPNQQTPPSMMPGAVPGS 1068 Query: 94 NNNGM-GAAPKPFPGGTGPP---------------------IKAEPK-------APYAPG 124 + G+ G AP P G PP + A P P+APG Sbjct: 1069 GHPGVAGNAPLGLPFGMPPPPPPPAPSIIPFGSLADSISINLPAPPNLHGHHHHLPFAPG 1128 Query: 125 TLPDSPPDSGSEAYSPQQVNEPHLLRTITPETL-CHVGVPSRLEHPP-----------PP 172 TLP PP+ +P N P T P +L G+ S P P Sbjct: 1129 TLP--PPNLPVSMANPLHPNLP--ATTTMPSSLPLGPGLGSAAAQSPAIVAAVQGNLLPS 1184 Query: 173 PAHLPGPPPPPPPPPHYP 190 + LP P P PP P P Sbjct: 1185 ASPLPDPGTPLPPDPTAP 1202 Score = 36.2 bits (82), Expect = 0.18 Identities = 52/175 (29%), Positives = 64/175 (36%), Gaps = 34/175 (19%) Query: 171 PPPAHLPGPPPPPPPPPHYPVLQRDLYMKAEPPIPHYAAMGQGLVPTDLHHTQQ-----S 225 PPPA PG P PP P L + +P A G G P L ++Q S Sbjct: 961 PPPALPPGSQPIPPTGAAGPPAVHGLAVAPASVVP--APAGSGAPPGSLGPSEQIGQAGS 1018 Query: 226 QMLHQLLQQHGAELP-----------THPSKKRKHSESPPSTLNAQMLNGMI--KQEPGT 272 Q Q GA P H + ++PPS M+ G + PG Sbjct: 1019 TAGPQQQQPAGAPQPGAVPPGVPPPGPHGPSPFPNQQTPPS-----MMPGAVPGSGHPGV 1073 Query: 273 VTALPLH-PTRAPSPPWPPQGPLSPGPGSLPLSIA-RVQTPP------WHPPGAP 319 PL P P PP PP + P GSL SI+ + PP H P AP Sbjct: 1074 AGNAPLGLPFGMPPPPPPPAPSIIPF-GSLADSISINLPAPPNLHGHHHHLPFAP 1127 >gi|18959210 WIRE protein [Homo sapiens] Length = 440 Score = 58.2 bits (139), Expect = 4e-08 Identities = 51/162 (31%), Positives = 64/162 (39%), Gaps = 37/162 (22%) Query: 69 PGGGPSPGRHGPLPPPGYG---TPLNCNNN-NGMGAAPKPFPGGTGPPIKAEPKAPYAPG 124 PG PGR GP PP +P+N +G AP P PP + P P P Sbjct: 213 PGQRLHPGREGPPAPPPVKPPPSPVNIRTGPSGQSLAPPP------PPYRQPPGVPNGP- 265 Query: 125 TLPDSPPDSGSEAYSPQQVNEPHL-----LRTITPETLCHVGVPSRLEHPPPPPAH---- 175 S P + S PQ+ N H +R + P PS L + PPPPA Sbjct: 266 ----SSPTNESAPELPQRHNSLHRKTPGPVRGLAPPPPTSAS-PSLLSNRPPPPARDPPS 320 Query: 176 ---LPGPPPP---------PPPPPHYPVLQRDLYMKAEPPIP 205 P PPPP PPPPP Y + + + +PP P Sbjct: 321 RGAAPPPPPPVIRNGARDAPPPPPPYRMHGSEPPSRGKPPPP 362 Score = 53.1 bits (126), Expect = 1e-06 Identities = 74/321 (23%), Positives = 104/321 (32%), Gaps = 61/321 (19%) Query: 32 DASDLCFPDISAPASSASYSHGQPAMPGSSGVHHLSPPGGGPSPGRHGPLPPPGYGTPLN 91 D+S P++ + +P S+G+ H S P PGR PP TPL Sbjct: 139 DSSRASLPELPRMQRPSLPDLSRPNTTSSTGMKHSSSAPPPPPPGRRANAPP----TPLP 194 Query: 92 CNNNNGMGA-APKPFPGGTGPPIKAEPKAPYAPGTLPDSPPDSGSEAYSPQQVNEPHLLR 150 +++ KP P G + + P AP P PP S P + + Sbjct: 195 MHSSKAPAYNREKPLPPTPGQRLHPGREGPPAPP--PVKPPPS------PVNIRTGPSGQ 246 Query: 151 TITPETLCHVGVPSRLEHPPPPPAHLPGPPPPPPPP-----PHYPVLQRDLYMKAEPPIP 205 ++ P PPPP PG P P P P P L+ K P+ Sbjct: 247 SLAP--------------PPPPYRQPPGVPNGPSSPTNESAPELPQRHNSLHRKTPGPV- 291 Query: 206 HYAAMGQGLVPTDLHHTQQSQMLHQLLQQHGAELPTHPSKKRKHSESPPSTLNAQMLNGM 265 +GL P S + ++ P P++ PPS G Sbjct: 292 ------RGLAPPPPTSASPSLLSNR---------PPPPAR------DPPS-------RGA 323 Query: 266 IKQEPGTVTALPLHPTRAPSPPWPPQGPLSPGPGSLPLSIARVQTPPWHPPGAPSPGLLQ 325 P V P PP+ G P G P +R P PP P + Sbjct: 324 APPPPPPVIRNGARDAPPPPPPYRMHGSEPPSRGKPPPPPSRTPAGPPPPPPPPLRNGHR 383 Query: 326 DSDSLSGSYLDPNYQSIKWQP 346 DS + S+LD + P Sbjct: 384 DSITTVRSFLDDFESKYSFHP 404 Score = 44.3 bits (103), Expect = 7e-04 Identities = 82/347 (23%), Positives = 111/347 (31%), Gaps = 90/347 (25%) Query: 34 SDLCFPDISAP-ASSASYSHGQPAMPGSSGVHH-----LSPPGGGPSPGRHGPLPPPGYG 87 +D P + P SS Y G A+ G+ L P G G P Sbjct: 57 NDRSAPILEKPKGSSGGYGSGGAALQPKGGLFQGGVLKLRPVGA--KDGSENLAGKPALQ 114 Query: 88 TPLNCNNNNGMGAAPKPFPGGTGPPIKAEPKAPYAPGTLPDSPPDSGSEAYSPQQVNEPH 147 P + AAP+P P+ A A G D S + ++ P Sbjct: 115 IP------SSRAAAPRP-------PVSA------ASGRPQDDTDSSRASLPELPRMQRPS 155 Query: 148 LLRTITPETLCHVGVPSRLEHPPPPP----AHLP-------------------------- 177 L P T G+ PPPPP A+ P Sbjct: 156 LPDLSRPNTTSSTGMKHSSSAPPPPPPGRRANAPPTPLPMHSSKAPAYNREKPLPPTPGQ 215 Query: 178 -------GPPPPPP-PPPHYPVLQR---DLYMKAEPPIPHYAAMGQGLVPTDLHHTQQSQ 226 GPP PPP PP PV R A PP P+ G P+ + ++ Sbjct: 216 RLHPGREGPPAPPPVKPPPSPVNIRTGPSGQSLAPPPPPYRQPPGVPNGPS----SPTNE 271 Query: 227 MLHQLLQQHGAELPTHPSKKRKHSESPPSTLNAQMLNGMIKQEPGTVTALPLHPTRAPSP 286 +L Q+H + P R + PP++ + +L+ P P P+R +P Sbjct: 272 SAPELPQRHNSLHRKTPGPVRGLAPPPPTSASPSLLS----NRPPPPARDP--PSRGAAP 325 Query: 287 PWPP--------QGPLSPGP----GSLPLSIARVQTPPWHPPGAPSP 321 P PP P P P GS P S + PP P P P Sbjct: 326 PPPPPVIRNGARDAPPPPPPYRMHGSEPPSRGKPPPPPSRTPAGPPP 372 Score = 37.4 bits (85), Expect = 0.080 Identities = 52/182 (28%), Positives = 69/182 (37%), Gaps = 22/182 (12%) Query: 190 PVLQRDLYMKAEPPIPHYAAMGQGLVPTDLHHTQQSQMLHQLLQQHGAELP------THP 243 P LQ A P P AA G+ TD L +L + LP T Sbjct: 111 PALQIPSSRAAAPRPPVSAASGRPQDDTDSSRAS----LPELPRMQRPSLPDLSRPNTTS 166 Query: 244 SKKRKHSES-PPSTLNAQMLNGMIKQEPGTVTALPLHPTRAPSPPWPPQGPLSPGPGSLP 302 S KHS S PP + N T LP+H ++AP+ + + PL P PG Sbjct: 167 STGMKHSSSAPPPPPPGRRANA-------PPTPLPMHSSKAPA--YNREKPLPPTPGQR- 216 Query: 303 LSIARVQTPPWHPPGAPSPGLLQDSDSLSGSYLDPNYQSIKWQPHQQNKWATLYDANYKE 362 L R + PP PP P P + SG L P + P N ++ + + E Sbjct: 217 LHPGR-EGPPAPPPVKPPPSPVNIRTGPSGQSLAPPPPPYRQPPGVPNGPSSPTNESAPE 275 Query: 363 LP 364 LP Sbjct: 276 LP 277 Score = 32.3 bits (72), Expect = 2.6 Identities = 17/32 (53%), Positives = 17/32 (53%), Gaps = 8/32 (25%) Query: 169 PPPPPAHLPGPPPPPPPPPH-----YPVLQRD 195 PPPPP P P PPPPP H P L RD Sbjct: 4 PPPPP---PPPGPPPPPTFHQANTEQPKLSRD 32 >gi|153792074 proline rich 12 [Homo sapiens] Length = 2036 Score = 57.8 bits (138), Expect = 6e-08 Identities = 57/182 (31%), Positives = 70/182 (38%), Gaps = 33/182 (18%) Query: 18 NIDTSILEEYISKEDASDLCFPDISAPASSASYSHGQPAMPGSSGVHHLSPPGGGP-SPG 76 N++T L + S E+ S D+ SSA + P + G S P G P +P Sbjct: 1373 NLET--LPSFSSDEEDSVAKNRDLQESISSAISALDDPPLAGPKDT---STPDGPPLAPA 1427 Query: 77 RHGPLPPPGYGTPLNCNNNNGMGAAPKPFPGGTGPPIKAEPKAPYAPGTLPDSPPDSGSE 136 P PPP G P + N+N GT P E K P P P P Sbjct: 1428 AAVPGPPPLPGLP-SANSN------------GTPEPPLLEEKPPPTPPPAPTPQPQPPPP 1474 Query: 137 AYSPQQ-VNEPHLLRTITPETLCHVGVPSRLEHPPPPPAHLPGPPPPPPP-------PPH 188 PQ + P L TP + P PPPPP +P PPPPPPP PP Sbjct: 1475 PPPPQPALPSPPPLVAPTPSS------PPPPPLPPPPPPAMPSPPPPPPPAAAPLAAPPE 1528 Query: 189 YP 190 P Sbjct: 1529 EP 1530 Score = 57.0 bits (136), Expect = 1e-07 Identities = 83/299 (27%), Positives = 106/299 (35%), Gaps = 54/299 (18%) Query: 39 PDISAPASSASYSHGQPAMPGSSGVHHLSPPGGGPSPGRHGPLP---PPGYGTPLNCNNN 95 P + P+ + + + G+ P ++G GGG G G P PGY T Sbjct: 346 PSKAGPSGATAGASGRATGPEAAG-------GGGAGGGGGGYRPIIQSPGYKTGKGGYGA 398 Query: 96 NGMGAAPKPFPGGTGPPIKAE----PKAPYAPGTLPDSPPDSGSEAYSPQQVNEPHLLRT 151 GA P P T P K + P A YA G + +G +AYSP Q P L Sbjct: 399 AAGGATRPPPPRSTATP-KCQSLGGPAAAYATGKASGAG-GAGGQAYSPGQ---PQGL-- 451 Query: 152 ITPETLCHVGVPSRLEHPPPPPAHLPGPPPPP--PPPPHYPV--------LQRDLYMKAE 201 + P+ + + P++ GPP PP PPPP LQ LY Sbjct: 452 LGPQAYGQGFGGGQAQDLSKAPSYSGGPPQPPSGPPPPGLATCQSYSPDQLQGQLYGVQG 511 Query: 202 PPIPHYAAMGQGLVPTDLHHTQQSQMLHQLLQQHGAELPTHPSKKRKHSESPPSTLNAQM 261 P P AA QGL PT S L HG PS E+ PS + Sbjct: 512 EPYPGPAAHSQGL-PTASPSLSYSTGHSPALSGHGGGWG--PSSLGGGGEASPSHI---- 564 Query: 262 LNGMIKQEPGTVTALPLHPTRAPSPPWPPQGPLSPGPGSLPLSIARVQTPPWHPPGAPS 320 + P ++P P G SPG LS P PPGA S Sbjct: 565 ----------------IRPLQSPPATGRPPGVGSPGAPGKYLSSVLASAPFLAPPGAGS 607 Score = 53.1 bits (126), Expect = 1e-06 Identities = 46/157 (29%), Positives = 57/157 (36%), Gaps = 31/157 (19%) Query: 34 SDLCFPDISAPASSASYSHGQPAMPGSSGVHHLSPPGGGPSPGRHGPLPPPGYGTPLNCN 93 + +CFPD S+ M G G G+ GP P G P Sbjct: 930 TSICFPDSLLQDEERSFFPTMEEMFGG---------GAADDYGKAGP--PEDEGDPK--- 975 Query: 94 NNNGMGAAPKPFPGGTGPPIKAEPKAPYAPGTLPDSPPDSGSEAYSPQQVNEPHLLRTIT 153 GA P P GPP +P PY PG + P++ P + P L T+ Sbjct: 976 ----AGAGPPP-----GPPAY-DPYGPYCPGRASGAGPETPGLGLDPNK--PPELPSTVN 1023 Query: 154 PETLCHVGVPSRLEHPPPPPAHLPGPPPPPPPPPHYP 190 E L + PPPPP PPPPPP P P Sbjct: 1024 AEPLGLIQSGPHQAAPPPPP-----PPPPPPAPASEP 1055 Score = 49.7 bits (117), Expect = 2e-05 Identities = 34/93 (36%), Positives = 38/93 (40%), Gaps = 21/93 (22%) Query: 100 AAPKPFPGGTGPPIKAEPKAPYAPGTLPDSPPDSGSEAYSPQQVNEPHLLRTITPETLCH 159 A PK GPP+ AP A +P PP G + + EP LL P Sbjct: 1411 AGPKDTSTPDGPPL-----APAA--AVPGPPPLPGLPSANSNGTPEPPLLEEKPP----- 1458 Query: 160 VGVPSRLEHPPPPPAHLPGPPPPPPPPPHYPVL 192 P PPPA P P PPPPPPP P L Sbjct: 1459 ---------PTPPPAPTPQPQPPPPPPPPQPAL 1482 Score = 41.2 bits (95), Expect = 0.006 Identities = 76/293 (25%), Positives = 95/293 (32%), Gaps = 82/293 (27%) Query: 51 SHGQPAMPGSS--GVHHLSPPGGGPSPGRHGPLPPPGYGTPLNCN---NNNGM-GAAPKP 104 SH P +S GVH L P +P P PPP PL ++G+ AAP P Sbjct: 807 SHAPSPSPSASKVGVHLLEPATRDGAPQPPPPPPPPPPPMPLQLEAHLRSHGLEPAAPSP 866 Query: 105 F---------PGGTGPPIKAEPKAPYAPGTLPDSPPDSGSE----AY---SPQQVNEPHL 148 PG + A P APG PP+S + AY SPQ P Sbjct: 867 RLRPEESLDPPGAMQELLGALEPLPPAPGDTGVGPPNSEGKDPAGAYRSPSPQGTKAPRF 926 Query: 149 L----------------RTITPETLCHVGVPSRLEHPPPPPAHLPGPPP----PPPPPPH 188 + R+ P G + ++ P G P PPP PP Sbjct: 927 VPLTSICFPDSLLQDEERSFFPTMEEMFGGGAADDYGKAGPPEDEGDPKAGAGPPPGPPA 986 Query: 189 YPVLQRDLYMKAEPPIPHYAAMGQGLVPTDLHHTQQSQMLHQLLQQHGAELPTHPSKKRK 248 Y +P P+ G G E P K Sbjct: 987 Y-----------DPYGPYCPGRASGA---------------------GPETPGLGLDPNK 1014 Query: 249 HSESPPSTLNAQMLNGMIKQEPGTVTALPLHPTRAPSPPWPPQGPLSPGPGSL 301 E PST+NA+ L G+I+ P P P PP PP P S G L Sbjct: 1015 PPEL-PSTVNAEPL-GLIQSGPHQAAPPP------PPPPPPPPAPASEPKGGL 1059 Score = 40.8 bits (94), Expect = 0.007 Identities = 57/246 (23%), Positives = 75/246 (30%), Gaps = 47/246 (19%) Query: 80 PLPPP----GYGTPLNCNNNNGMGAAPKPFPGGTGPPIKAEPKAPYAPGTLPDSPPDSGS 135 P PPP G G L + G+G G P + + + TLP D Sbjct: 1333 PHPPPSGAFGLGGALEAAESEGLGL------GCPSPCKRLDEELKRNLETLPSFSSDEED 1386 Query: 136 EAYSPQQVNEPHLLRTITPETLCHVGVPSRLEHPPPPPAHLPGPPPPPPPPPHYPVLQRD 195 + + E + S + PP P P PP P Sbjct: 1387 SVAKNRDLQE---------------SISSAISALDDPPLAGPKDTSTPDGPPLAPAAA-- 1429 Query: 196 LYMKAEPPIPHYAAMGQGLVPTDLHHTQQSQMLHQLLQQHGAELPTHPSKKRKHSESPPS 255 + PP+P GL + + T + +L + PT P + PP Sbjct: 1430 --VPGPPPLP-------GLPSANSNGTPEPPLLEE------KPPPTPPPAPTPQPQPPPP 1474 Query: 256 TLNAQMLNGMIKQEPGTVTALPLHPTRAPSPPWPPQGPLSPGPGSLPLSIARVQTPPWHP 315 Q + P V P P P PP PP P P P P A P Sbjct: 1475 PPPPQPA---LPSPPPLVAPTPSSPPPPPLPPPPP--PAMPSPPPPPPPAAAPLAAPPEE 1529 Query: 316 PGAPSP 321 P APSP Sbjct: 1530 PAAPSP 1535 Score = 40.0 bits (92), Expect = 0.012 Identities = 33/90 (36%), Positives = 43/90 (47%), Gaps = 9/90 (10%) Query: 103 KPFPGGTGPPIKAEPKAPYAPGTLPDSPPDSGSEAYSPQQVNEPHLLRTITPETLCHVGV 162 +PFP + ++ P +P A G L SP D P Q P + ++ E L GV Sbjct: 160 RPFPVPSSLSLQDPPFSPPANGLL--SPHDVLH--LKPSQA--PTVPSSLGFERLAGGGV 213 Query: 163 --PSRLEHPPPPPAHLPGPPPPPPPPPHYP 190 P+ L P P + PGPP PPPPP H P Sbjct: 214 LGPAGLG-PAQTPPYRPGPPDPPPPPRHLP 242 Score = 38.9 bits (89), Expect = 0.027 Identities = 40/133 (30%), Positives = 48/133 (36%), Gaps = 31/133 (23%) Query: 104 PFPGGTGPPIKAEPKAPYAPGT------LPDSPPDSGSEAYSPQQVNEPHLLRTITPETL 157 P GG P A Y G L SPP A S Q LL P+ Sbjct: 732 PERGGETPEGLATSVVHYGAGAKELGAFLQKSPPPPPPTAQSTQPTPHGLLLEAGGPDLP 791 Query: 158 CHVG------VPSRLEHPPPPP-------AHL---------PGPPPPPPPPPHYPVLQRD 195 + +PS L H P P HL P PPPPPPPPP LQ + Sbjct: 792 LVLPPPPPQLLPSVLSHAPSPSPSASKVGVHLLEPATRDGAPQPPPPPPPPPPPMPLQLE 851 Query: 196 LYMKA---EPPIP 205 ++++ EP P Sbjct: 852 AHLRSHGLEPAAP 864 Score = 37.4 bits (85), Expect = 0.080 Identities = 48/182 (26%), Positives = 58/182 (31%), Gaps = 53/182 (29%) Query: 44 PASSASYSHGQPAMPGS------SGVHHLSPPGGGPSPGRHGP-----LPPPGYGTPLNC 92 P+SSA ++ PA GS S + PP P+ G P L P T + Sbjct: 143 PSSSALSAYQHPASFGSRPFPVPSSLSLQDPPFSPPANGLLSPHDVLHLKPSQAPTVPSS 202 Query: 93 NNNNGMGAAPKPFPGGTGPPIKAEPKAPYAPGTLPDSPPD------------SGSEAYSP 140 + P G GP PY PG PD PP S S A + Sbjct: 203 LGFERLAGGGVLGPAGLGPA----QTPPYRPGP-PDPPPPPRHLPTQFNLLASSSAAAAA 257 Query: 141 QQVNEPHLLRTITPETLCHVGVPSRLEHPPPPPAHLP--------------GPPPPPPPP 186 + + P L PPPP LP PPPPPPP Sbjct: 258 AEQSSPQLYN-----------FSGAAPGPPPPERALPRQDTVIKHYQRPASAQPPPPPPP 306 Query: 187 PH 188 H Sbjct: 307 AH 308 Score = 35.8 bits (81), Expect = 0.23 Identities = 26/71 (36%), Positives = 30/71 (42%), Gaps = 8/71 (11%) Query: 271 GTVTALPLHPTRAPSPPWPPQGPLSPG--------PGSLPLSIARVQTPPWHPPGAPSPG 322 G L P+ + PP PP GP PG P L + VQ P+ P A S G Sbjct: 464 GQAQDLSKAPSYSGGPPQPPSGPPPPGLATCQSYSPDQLQGQLYGVQGEPYPGPAAHSQG 523 Query: 323 LLQDSDSLSGS 333 L S SLS S Sbjct: 524 LPTASPSLSYS 534 Score = 34.3 bits (77), Expect = 0.67 Identities = 49/177 (27%), Positives = 64/177 (36%), Gaps = 32/177 (18%) Query: 172 PPAHLPG--PP--PPPPPPPHYPVLQRDLYMKAEPPIPH-------------YAAMGQGL 214 PP + G PP PP PP P A P +PH AA +GL Sbjct: 1296 PPLYQAGLTPPLSPPKSVPPSVPARGLQPQPPATPAVPHPPPSGAFGLGGALEAAESEGL 1355 Query: 215 VPTDLHHTQQSQMLHQLLQQHGAELPTHPS-------KKRKHSESPPSTLNA---QMLNG 264 L + L + L+++ LP+ S K R ES S ++A L G Sbjct: 1356 ---GLGCPSPCKRLDEELKRNLETLPSFSSDEEDSVAKNRDLQESISSAISALDDPPLAG 1412 Query: 265 MIKQEPGTVTALPLHPTRAPSPPWPPQGPLSPGPGSLPLSIARVQTPPWHPPGAPSP 321 ++ T PL P A P P G S P + PP PP AP+P Sbjct: 1413 --PKDTSTPDGPPLAPAAAVPGPPPLPGLPSANSNGTPEPPLLEEKPPPTPPPAPTP 1467 Score = 33.1 bits (74), Expect = 1.5 Identities = 31/117 (26%), Positives = 38/117 (32%), Gaps = 12/117 (10%) Query: 70 GGGPSPGRHGPLPPPGYGTPLNCNNNNGMGAAPKPFPGGTGPPIKAEPKAPYAPGTLPDS 129 GG +P P PPP TP + KP P T EP AP P L Sbjct: 1687 GGSSAPPPKAPAPPPKPETPEKTTSE-------KP-PEQTPETAMPEPPAPEKPSLLRPV 1738 Query: 130 PPDSGSEAYS----PQQVNEPHLLRTITPETLCHVGVPSRLEHPPPPPAHLPGPPPP 182 + E + P + R PE G P+ P P + PPP Sbjct: 1739 EKEKEKEKVTRGERPLRGERATSGRQTRPERSLATGQPATSRLPKARPTKVKAEPPP 1795 Score = 32.0 bits (71), Expect = 3.3 Identities = 24/82 (29%), Positives = 32/82 (39%), Gaps = 19/82 (23%) Query: 54 QPAMPGSSGVHHLSPPGGGPSPGRHGPLPPPGYGTPLNCNNNNGMGAAPKPFPGGTGPPI 113 QPA+P + ++P P P P PPP +P P P P+ Sbjct: 1479 QPALPSPPPL--VAPTPSSPPPPPLPPPPPPAM-------------PSPPPPPPPAAAPL 1523 Query: 114 KAEPKAPYAPG----TLPDSPP 131 A P+ P AP LPD+ P Sbjct: 1524 AAPPEEPAAPSPEDPELPDTRP 1545 >gi|55750053 atrophin-1 [Homo sapiens] Length = 1190 Score = 57.4 bits (137), Expect = 7e-08 Identities = 85/298 (28%), Positives = 104/298 (34%), Gaps = 57/298 (19%) Query: 44 PASSA--SYSHGQPAMPGSSGVHHLSPPGGGPS-PGR----HGPLPPPGYGTPLNCNNNN 96 PAS A SY H P P S V + P PS P + GP PPP YG L +N Sbjct: 400 PASQALPSYPHSFPP-PTSLSVSNQPPKYTQPSLPSQAVWSQGPPPPPPYGRLLANSN-- 456 Query: 97 GMGAAPKPFPGGTGPPIKAEPKAPYAPGTLPDSPPDSGSEAYSPQQVNEPHLLRTITPET 156 A P PFP TG A P + QQ + H P Sbjct: 457 ---AHPGPFPPSTGAQSTAHPPVSTHHHHHQQQQQQQQQQQQQQQQQQQHHGNSGPPPPG 513 Query: 157 LCHVGVPSRLEHPPPPPAHLPG-----PPPPPP---PPPHYPVLQRDLYMKAEPPIPHYA 208 + H P A P P PP P PPPH V Y +A P P + Sbjct: 514 AFPHPLEGGSSHHAHPYAMSPSLGSLRPYPPGPAHLPPPHSQVS----YSQAGPNGPPVS 569 Query: 209 AMG-------QGLVPTDLHHTQQSQMLHQLLQQHGAELPTHPSKKRKHSESPPSTLNAQM 261 + QG P H SQ GA P P P T ++ Sbjct: 570 SSSNSSSSTSQGSYPCS--HPSPSQ------GPQGAPYPFPPV--------PTVTTSSAT 613 Query: 262 LNGMIKQEPGTVTALPLHPTRAPSPPWPPQGPLSPGPGSLPLSIARVQTPPWHPPGAP 319 L+ +I TV + P A P PP G +P PG+ + TPP + PG+P Sbjct: 614 LSTVI----ATVASSPAGYKTASPPGPPPYGKRAPSPGAY-----KTATPPGYKPGSP 662 Score = 56.2 bits (134), Expect = 2e-07 Identities = 84/314 (26%), Positives = 106/314 (33%), Gaps = 38/314 (12%) Query: 42 SAPASSASYSHGQPAMPGSSGVHHL-----SPPGGGPSPGRHGPLPPPGY------GTPL 90 SAP A++ H P +P + L SPPG G P G LP P G P Sbjct: 287 SAPPP-ANFPHVTPNLPPPPALRPLNNASASPPGLGAQP-LPGHLPSPHAMGQGMGGLPP 344 Query: 91 NCNNNNGMGAAPKPFPGGTG----PPIKAEPKAPYAPGTLPDSPPDSGSEAYSPQQVNE- 145 + +P P + PP++ + + S S S + SP ++ Sbjct: 345 GPEKGPTLAPSPHSLPPASSSAPAPPMRFPYSSSSSSSAAASSSSSSSSSSASPFPASQA 404 Query: 146 -PHLLRTITPETLCHVG-VPSRLEHPPPPPAHLPGPPPPPPPPPHYPVLQRDLYMKAEPP 203 P + P T V P + P P + PPPPPP Y L + P Sbjct: 405 LPSYPHSFPPPTSLSVSNQPPKYTQPSLPSQAVWSQGPPPPPP--YGRLLANSNAHPGPF 462 Query: 204 IPHYAAMGQGLVP--TDLHHTQQSQMLHQLLQQHGAELPTHPSKKRKHSESPPSTLNAQM 261 P A P T HH QQ Q Q QQ + H +S PP Sbjct: 463 PPSTGAQSTAHPPVSTHHHHHQQQQQQQQQQQQQQQQQQQH----HGNSGPPPPGAFPHP 518 Query: 262 LNGMIKQEPGTVTALPLHPTRAPSPPWPPQGPLSPGPGSLPLSIARVQTPPWHPPGAPSP 321 L G HP A SP P PGP LP ++V P G P Sbjct: 519 LEGGSSHH--------AHP-YAMSPSLGSLRPYPPGPAHLPPPHSQVSYSQAGPNGPPVS 569 Query: 322 GLLQDSDSLS-GSY 334 S S S GSY Sbjct: 570 SSSNSSSSTSQGSY 583 Score = 52.8 bits (125), Expect = 2e-06 Identities = 75/294 (25%), Positives = 104/294 (35%), Gaps = 59/294 (20%) Query: 56 AMPGSSGVHHLSPPGGGPSPGRHGPLPPPGYGTPLNCNNNNGMGAAPKPFP-------GG 108 A PG+ H PGG P+ P G G + NG P P G Sbjct: 208 APPGAPPPHPQLYPGGTGGVLSGPPMGPKGGGAASSVGGPNGGKQHPPPTTPISVSSSGA 267 Query: 109 TGPPIKAEPKAPYAPGTLPDSPPDSGSEAYSPQQVNEPHLLRTITPETLCHVGVPSRLEH 168 +G P P P G LP +PP + +P + P LR + + G+ ++ Sbjct: 268 SGAPPTKPPTTPVGGGNLPSAPPPANFPHVTP-NLPPPPALRPLNNASASPPGLGAQ--- 323 Query: 169 PPPPPAHLPGP----------PPPP------PPPPHYPVLQRDLYMKAEPPI--PHYAAM 210 P P HLP P PP P P PH L PP+ P+ ++ Sbjct: 324 --PLPGHLPSPHAMGQGMGGLPPGPEKGPTLAPSPH--SLPPASSSAPAPPMRFPYSSSS 379 Query: 211 GQGLVPTDLHHTQQSQMLHQLLQQHGAELPTHPSKKRKHSESPPSTLNAQMLNGMIKQEP 270 + + S Q LP++P HS PP++L+ + +P Sbjct: 380 SSSAAASSSSSSSSSSASPFPASQ---ALPSYP-----HSFPPPTSLS-------VSNQP 424 Query: 271 GTVTALPLHPTRA----PSPPWPPQGPL----SPGPGSLPLSIARVQTPPWHPP 316 T P P++A PP PP G L + PG P S T HPP Sbjct: 425 PKYTQ-PSLPSQAVWSQGPPPPPPYGRLLANSNAHPGPFPPSTGAQSTA--HPP 475 Score = 50.1 bits (118), Expect = 1e-05 Identities = 47/164 (28%), Positives = 59/164 (35%), Gaps = 33/164 (20%) Query: 38 FPDISAPASSASYSHGQPAMPGSS--GVHHLSPPGG------GPSPGRHGPLPPPGY--G 87 FP + +S++ A SS G SPPG PSPG + PPGY G Sbjct: 601 FPPVPTVTTSSATLSTVIATVASSPAGYKTASPPGPPPYGKRAPSPGAYKTATPPGYKPG 660 Query: 88 TPLNCNNNNGMGAAPKPFPGGTG------PPIKAEPKAPYAPGTLPDSPPDSGSEAYSPQ 141 +P + G P G G P + P P P LP PP + A P Sbjct: 661 SPPSFRTGTPPGYRGTSPPAGPGTFKPGSPTVGPGPLPPAGPSGLPSLPPPPAAPASGPP 720 Query: 142 ----QVNEPHLLRTITPETLCHVGVPSRLEHPPPPPAHLPGPPP 181 Q+ + TPE+ P PPA P PPP Sbjct: 721 LSATQIKQEPAEEYETPES-------------PVPPARSPSPPP 751 Score = 45.1 bits (105), Expect = 4e-04 Identities = 65/275 (23%), Positives = 93/275 (33%), Gaps = 60/275 (21%) Query: 42 SAPASSASYSHGQPAMPGSSGVHHLSPPGGGPSPGRHGPLPP-PGY-------------- 86 S P ++ H P GSS HH P PS G P PP P + Sbjct: 507 SGPPPPGAFPH--PLEGGSS--HHAHPYAMSPSLGSLRPYPPGPAHLPPPHSQVSYSQAG 562 Query: 87 --GTPLNCNNNNGMGAAPKPFPGGTGPPIKAEPKAPYAPGTLPDSPPDSGSEAYSPQQV- 143 G P++ ++N+ + +P P + APY +P S + + V Sbjct: 563 PNGPPVSSSSNSSSSTSQGSYPCSHPSPSQGPQGAPYPFPPVPTVTTSSATLSTVIATVA 622 Query: 144 NEPHLLRTITPETLCHVGVPSRLEHPPPPPAHLPGPPP--PPPPPPHYPVLQRDLYMKAE 201 + P +T +P G P + P P A+ PP P PP + Y Sbjct: 623 SSPAGYKTASPP-----GPPPYGKRAPSPGAYKTATPPGYKPGSPPSFRTGTPPGYRGTS 677 Query: 202 PPI------PHYAAMGQGLVPTDLHHTQQSQMLHQLLQQHGAELPTHPSKKRKHSESPPS 255 PP P +G G +P + LP+ P + PP Sbjct: 678 PPAGPGTFKPGSPTVGPGPLPP----------------AGPSGLPSLPPPPAAPASGPPL 721 Query: 256 TLNAQMLNGMIKQEPGT---VTALPLHPTRAPSPP 287 + IKQEP P+ P R+PSPP Sbjct: 722 SAT------QIKQEPAEEYETPESPVPPARSPSPP 750 Score = 40.0 bits (92), Expect = 0.012 Identities = 73/279 (26%), Positives = 89/279 (31%), Gaps = 71/279 (25%) Query: 117 PKAPYAPGTL-PDSPPDSGSEAYSPQQVNEPHLLRTITPETLCHVGVPSRLEHPPPPPAH 175 P PY P L P SP S P+ EPH T P+ P PP Sbjct: 155 PARPYHPPPLFPPSPQPPDSTPRQPEASFEPHPSVT-----------PTGYHAPMEPPTS 203 Query: 176 LPGPPPPPPPPPH---YP-----VLQ--------------------RDLYMKAEPPIPHY 207 PP PPPH YP VL + PI Sbjct: 204 RMFQAPPGAPPPHPQLYPGGTGGVLSGPPMGPKGGGAASSVGGPNGGKQHPPPTTPISVS 263 Query: 208 AAMGQGLVPTDLHHTQQSQMLHQLLQQHGAELPTHPSKKRKHSESP--PSTLNAQMLNGM 265 ++ G PT T G LP+ P +P P + LN Sbjct: 264 SSGASGAPPTKPPTTPVG----------GGNLPSAPPPANFPHVTPNLPPPPALRPLNNA 313 Query: 266 IKQEPGTVTALPLHPTRAPS-----------PPWPPQGP-LSPGPGSLPLSIARVQTPPW 313 PG + A PL P PS PP P +GP L+P P SLP + + PP Sbjct: 314 SASPPG-LGAQPL-PGHLPSPHAMGQGMGGLPPGPEKGPTLAPSPHSLPPASSSAPAPPM 371 Query: 314 HPP---GAPSPGLLQDSDSLSGSYLD--PNYQSIKWQPH 347 P + S S S S S P Q++ PH Sbjct: 372 RFPYSSSSSSSAAASSSSSSSSSSASPFPASQALPSYPH 410 Score = 31.2 bits (69), Expect = 5.7 Identities = 45/181 (24%), Positives = 61/181 (33%), Gaps = 24/181 (13%) Query: 164 SRLEHPPPPPAHLPGPPPPPPPPPHYPVLQRDLYMKAEPPIPHYAAMGQGLVPTDLHHTQ 223 S L P P H P PP P PP Q + + P + PT H Sbjct: 149 SGLSQGPARPYHPPPLFPPSPQPPDSTPRQPEASFEPHPSV----------TPTGYHAPM 198 Query: 224 QSQMLHQLLQQHGAELP---THPSKKRKHSESPP-------STLNAQMLNGMIKQEPGTV 273 + GA P +P PP + + NG KQ P Sbjct: 199 EPPTSRMFQAPPGAPPPHPQLYPGGTGGVLSGPPMGPKGGGAASSVGGPNGG-KQHPPPT 257 Query: 274 TALPLHPTRAPSPPWPPQGPLSP-GPGSLPLSIARVQTPPWHPPGAPSPGLLQDSDSLSG 332 T + + + A P P + P +P G G+LP S P P P P L+ ++ S Sbjct: 258 TPISVSSSGASGAP-PTKPPTTPVGGGNLP-SAPPPANFPHVTPNLPPPPALRPLNNASA 315 Query: 333 S 333 S Sbjct: 316 S 316 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.314 0.132 0.403 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 56,927,570 Number of Sequences: 37866 Number of extensions: 3790423 Number of successful extensions: 47121 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 528 Number of HSP's successfully gapped in prelim test: 1269 Number of HSP's that attempted gapping in prelim test: 19276 Number of HSP's gapped (non-prelim): 13982 length of query: 1111 length of database: 18,247,518 effective HSP length: 113 effective length of query: 998 effective length of database: 13,968,660 effective search space: 13940722680 effective search space used: 13940722680 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 42 (22.0 bits) S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.