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Search of human proteins with 13899267
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|13899267 nudix-type motif 12 [Homo sapiens]
(462 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|13899267 nudix-type motif 12 [Homo sapiens] 948 0.0
gi|50593112 nudix-type motif 13 [Homo sapiens] 163 3e-40
gi|4506499 regulatory factor X-associated ankyrin-containing pro... 59 9e-09
gi|12746412 ankyrin repeat, family A (RFXANK-like), 2 [Homo sapi... 59 1e-08
gi|225543463 tetratricopeptide repeat, ankyrin repeat and coiled... 54 3e-07
gi|225543461 tetratricopeptide repeat, ankyrin repeat and coiled... 54 3e-07
gi|50511945 cajalin 2 isoform a [Homo sapiens] 54 3e-07
gi|19924156 regulatory factor X-associated ankyrin-containing pr... 51 3e-06
gi|148596917 fibronectin type III and ankyrin repeat domains 1 [... 50 3e-06
gi|32967601 ankyrin 3 isoform 1 [Homo sapiens] 50 3e-06
gi|140161500 ankyrin repeat and sterile alpha motif domain conta... 50 4e-06
gi|46519154 ankyrin repeat and KH domain containing 1 isoform 3 ... 50 4e-06
gi|46519151 ankyrin repeat and KH domain containing 1 isoform 2 ... 50 4e-06
gi|46519147 ankyrin repeat and KH domain containing 1 isoform 1 ... 50 4e-06
gi|37620163 ANKHD1-EIF4EBP3 protein [Homo sapiens] 50 4e-06
gi|21264330 mindbomb homolog 2 [Homo sapiens] 50 4e-06
gi|154354990 ankyrin repeat domain 26 [Homo sapiens] 50 4e-06
gi|116325987 ankyrin repeat domain 42 [Homo sapiens] 50 4e-06
gi|90186267 ankyrin repeat domain 55 isoform 1 [Homo sapiens] 50 6e-06
gi|156142199 euchromatic histone-lysine N-methyltransferase 2 is... 49 7e-06
gi|156142197 euchromatic histone-lysine N-methyltransferase 2 is... 49 7e-06
gi|157743284 ankyrin repeat domain 52 [Homo sapiens] 49 7e-06
gi|38683807 ankyrin repeat domain protein 17 isoform a [Homo sap... 49 7e-06
gi|38683816 ankyrin repeat domain protein 17 isoform b [Homo sap... 49 7e-06
gi|224465233 euchromatic histone-lysine N-methyltransferase 1 is... 49 1e-05
gi|156142184 ankyrin repeat domain 39 [Homo sapiens] 49 1e-05
gi|37221184 krev interaction trapped 1 isoform 1 [Homo sapiens] 48 2e-05
gi|37221182 krev interaction trapped 1 isoform 1 [Homo sapiens] 48 2e-05
gi|37221187 krev interaction trapped 1 isoform 1 [Homo sapiens] 48 2e-05
gi|31581522 krev interaction trapped 1 isoform 1 [Homo sapiens] 48 2e-05
>gi|13899267 nudix-type motif 12 [Homo sapiens]
Length = 462
Score = 948 bits (2450), Expect = 0.0
Identities = 462/462 (100%), Positives = 462/462 (100%)
Query: 1 MSSVKRSLKQEIVTQFHCSAAEGDIAKLTGILSHSPSLLNETSENGWTALMYAARNGHPE 60
MSSVKRSLKQEIVTQFHCSAAEGDIAKLTGILSHSPSLLNETSENGWTALMYAARNGHPE
Sbjct: 1 MSSVKRSLKQEIVTQFHCSAAEGDIAKLTGILSHSPSLLNETSENGWTALMYAARNGHPE 60
Query: 61 IVQFLLEKGCDRSIVNKSRQTALDIAVFWGYKHIANLLATAKGGKKPWFLTNEVEECENY 120
IVQFLLEKGCDRSIVNKSRQTALDIAVFWGYKHIANLLATAKGGKKPWFLTNEVEECENY
Sbjct: 61 IVQFLLEKGCDRSIVNKSRQTALDIAVFWGYKHIANLLATAKGGKKPWFLTNEVEECENY 120
Query: 121 FSKTLLDRKSEKRNNSDWLLAKESHPATVFILFSDLNPLVTLGGNKESFQQPEVRLCQLN 180
FSKTLLDRKSEKRNNSDWLLAKESHPATVFILFSDLNPLVTLGGNKESFQQPEVRLCQLN
Sbjct: 121 FSKTLLDRKSEKRNNSDWLLAKESHPATVFILFSDLNPLVTLGGNKESFQQPEVRLCQLN 180
Query: 181 YTDIKDYLAQPEKITLIFLGVELEIKDKLLNYAGEVPREEEDGLVAWFALGIDPIAAEEF 240
YTDIKDYLAQPEKITLIFLGVELEIKDKLLNYAGEVPREEEDGLVAWFALGIDPIAAEEF
Sbjct: 181 YTDIKDYLAQPEKITLIFLGVELEIKDKLLNYAGEVPREEEDGLVAWFALGIDPIAAEEF 240
Query: 241 KQRHENCYFLHPPMPALLQLKEKEAGVVAQARSVLAWHSRYKFCPTCGNATKIEEGGYKR 300
KQRHENCYFLHPPMPALLQLKEKEAGVVAQARSVLAWHSRYKFCPTCGNATKIEEGGYKR
Sbjct: 241 KQRHENCYFLHPPMPALLQLKEKEAGVVAQARSVLAWHSRYKFCPTCGNATKIEEGGYKR 300
Query: 301 LCLKEDCPSLNGVHNTSYPRVDPVVIMQVIHPDGTKCLLGRQKRFPPGMFTCLAGFIEPG 360
LCLKEDCPSLNGVHNTSYPRVDPVVIMQVIHPDGTKCLLGRQKRFPPGMFTCLAGFIEPG
Sbjct: 301 LCLKEDCPSLNGVHNTSYPRVDPVVIMQVIHPDGTKCLLGRQKRFPPGMFTCLAGFIEPG 360
Query: 361 ETIEDAVRREVEEESGVKVGHVQYVACQPWPMPSSLMIGCLALAVSTEIKVDKNEIEDAR 420
ETIEDAVRREVEEESGVKVGHVQYVACQPWPMPSSLMIGCLALAVSTEIKVDKNEIEDAR
Sbjct: 361 ETIEDAVRREVEEESGVKVGHVQYVACQPWPMPSSLMIGCLALAVSTEIKVDKNEIEDAR 420
Query: 421 WFTREQVLDVLTKGKQQAFFVPPSRAIAHQLIKHWIRINPNL 462
WFTREQVLDVLTKGKQQAFFVPPSRAIAHQLIKHWIRINPNL
Sbjct: 421 WFTREQVLDVLTKGKQQAFFVPPSRAIAHQLIKHWIRINPNL 462
>gi|50593112 nudix-type motif 13 [Homo sapiens]
Length = 352
Score = 163 bits (413), Expect = 3e-40
Identities = 116/307 (37%), Positives = 164/307 (53%), Gaps = 45/307 (14%)
Query: 176 LCQLNYTDIKDYLAQPEKITLIFLGVELEIKDKLLNYAGEVPREEEDGLV-------AWF 228
L L T YLA + LE++ L + + R E+ L+ AWF
Sbjct: 55 LAPLLQTSAHQYLAPRHSL--------LELERLLGKFGQDAQRIEDSVLIGCSEQQEAWF 106
Query: 229 AL--GIDP---IAAEEFKQRHENCY---FLHPPMPALLQLKEKEAGVVAQARSVLAWHSR 280
AL G+D I+A K E F+ AL QL ++A +++ A+++L WH
Sbjct: 107 ALDLGLDSSFSISASLHKPEMETELKGSFIEL-RKALFQLNARDASLLSTAQALLRWHDA 165
Query: 281 YKFCPTCGNATKIEEGGYKRLCLKEDCPSLNGVHNTSYPRVDPVVIMQVIHPDGTKCLLG 340
++FC G TK G KR+C PS N ++ YP++ PV I V DGT+CLL
Sbjct: 166 HQFCSRSGQPTKKNVAGSKRVC-----PSNNIIY---YPQMAPVAITLV--SDGTRCLLA 215
Query: 341 RQKRFPPGMFTCLAGFIEPGETIEDAVRREVEEESGVKVGHVQYVACQPWPMPS-SLMIG 399
RQ FP GM++ LAGF + GE++E+ +RREV EE G++V +QY A Q WP PS SLMI
Sbjct: 216 RQSSFPKGMYSALAGFCDIGESVEETIRREVAEEVGLEVESLQYYASQHWPFPSGSLMIA 275
Query: 400 CLALAV--STEIKVDKNEIEDARWFTREQVLDVLTK----GKQQ----AFFVPPSRAIAH 449
C A TEI+V+ E+E A WF+ ++V L + +QQ F++PP AI+H
Sbjct: 276 CHATVKPGQTEIQVNLRELETAAWFSHDEVATALKRKGPYTQQQNGTFPFWLPPKLAISH 335
Query: 450 QLIKHWI 456
QLIK W+
Sbjct: 336 QLIKEWV 342
>gi|4506499 regulatory factor X-associated ankyrin-containing
protein isoform a [Homo sapiens]
Length = 260
Score = 58.9 bits (141), Expect = 9e-09
Identities = 33/82 (40%), Positives = 49/82 (59%)
Query: 17 HCSAAEGDIAKLTGILSHSPSLLNETSENGWTALMYAARNGHPEIVQFLLEKGCDRSIVN 76
H AA+G++ +L L +L+N+ E G+T L++A+ G E V+FLLE G D I+
Sbjct: 95 HQLAAQGELDQLKEHLRKGDNLVNKPDERGFTPLIWASAFGEIETVRFLLEWGADPHILA 154
Query: 77 KSRQTALDIAVFWGYKHIANLL 98
K R++AL +A GY I LL
Sbjct: 155 KERESALSLASTGGYTDIVGLL 176
Score = 46.6 bits (109), Expect = 5e-05
Identities = 25/79 (31%), Positives = 40/79 (50%)
Query: 20 AAEGDIAKLTGILSHSPSLLNETSENGWTALMYAARNGHPEIVQFLLEKGCDRSIVNKSR 79
A+ G + G+L +N NG T L+YA R H + V+ LL +G D + S
Sbjct: 164 ASTGGYTDIVGLLLERDVDINIYDWNGGTPLLYAVRGNHVKCVEALLARGADLTTEADSG 223
Query: 80 QTALDIAVFWGYKHIANLL 98
T +D+AV GY+ + ++
Sbjct: 224 YTPMDLAVALGYRKVQQVI 242
>gi|12746412 ankyrin repeat, family A (RFXANK-like), 2 [Homo
sapiens]
Length = 313
Score = 58.5 bits (140), Expect = 1e-08
Identities = 30/82 (36%), Positives = 49/82 (59%), Gaps = 1/82 (1%)
Query: 17 HCSAAEGDIAKLTGILSHSPSLLNETSENGWTALMYAARNGHPEIVQFLLEKGCDRSIVN 76
H AA+G++ L + +++N T E G+T LM+AA +G +V+FLL+ G D ++
Sbjct: 154 HQLAAQGEMLYLATRIEQE-NVINHTDEEGFTPLMWAAAHGQIAVVEFLLQNGADPQLLG 212
Query: 77 KSRQTALDIAVFWGYKHIANLL 98
K R++AL +A GY I +L
Sbjct: 213 KGRESALSLACSKGYTDIVKML 234
Score = 48.1 bits (113), Expect = 2e-05
Identities = 29/89 (32%), Positives = 43/89 (48%), Gaps = 3/89 (3%)
Query: 10 QEIVTQFHCSAAEGDIAKLTGILSHSPSLLNETSENGWTALMYAARNGHPEIVQFLLEKG 69
+E CS DI K+ L +NE NG T L+YA H + V+ LLE G
Sbjct: 215 RESALSLACSKGYTDIVKM---LLDCGVDVNEYDWNGGTPLLYAVHGNHVKCVKMLLESG 271
Query: 70 CDRSIVNKSRQTALDIAVFWGYKHIANLL 98
D +I S ++D+AV GY+ + ++
Sbjct: 272 ADPTIETDSGYNSMDLAVALGYRSVQQVI 300
>gi|225543463 tetratricopeptide repeat, ankyrin repeat and coiled-coil
containing 1 isoform 2 [Homo sapiens]
Length = 1390
Score = 53.9 bits (128), Expect = 3e-07
Identities = 50/176 (28%), Positives = 78/176 (44%), Gaps = 19/176 (10%)
Query: 14 TQFHCSAAEGDIAKLTGILSHSPSLLNETSENGWTALMYAARNGHPEIVQFLLEKGCDRS 73
T +A EG ++ + +LS +L + + G +AL +A GH +VQ+L+E+G
Sbjct: 1139 TPLMVAACEGHLSTVEFLLSKGAAL-SSLDKEGLSALSWACLKGHRAVVQYLVEEGAAID 1197
Query: 74 IVNKSRQTALDIAVFWGYKHIANLLATAKG---------GKKPWFLTNEVEECENYFSKT 124
+K+ +T LD+A F+G L KG G +P + C N
Sbjct: 1198 QTDKNGRTPLDLAAFYGDAETV-LYLVEKGAVIEHVDHSGMRP---LDRAIGCRNTSVVV 1253
Query: 125 LLDRKSEKRNNSDWLLAKESHPATVFILFSDL----NPLVTLGGNKESFQQPEVRL 176
L RK K N+ W +A S P + IL L N + G KE+ Q+ + L
Sbjct: 1254 ALLRKGAKLGNAAWAMA-TSKPDILIILLQKLMEEGNVMYKKGKMKEAAQRYQYAL 1308
Score = 45.4 bits (106), Expect = 1e-04
Identities = 26/78 (33%), Positives = 42/78 (53%), Gaps = 1/78 (1%)
Query: 14 TQFHCSAAEGDIAKLTGILSHSPSLLNETSENGWTALMYAARNGHPEIVQFLLEKGCDRS 73
T +A G + +L H ++ + T+ G L AAR GH +IV+ LLE+GCD +
Sbjct: 1073 TALTAAAGRGKLEVCELLLGHGAAV-SRTNRRGVPPLFCAARQGHWQIVRLLLERGCDVN 1131
Query: 74 IVNKSRQTALDIAVFWGY 91
+ +K +T L +A G+
Sbjct: 1132 LSDKQGRTPLMVAACEGH 1149
Score = 43.5 bits (101), Expect = 4e-04
Identities = 27/69 (39%), Positives = 36/69 (52%)
Query: 39 LNETSENGWTALMYAARNGHPEIVQFLLEKGCDRSIVNKSRQTALDIAVFWGYKHIANLL 98
L+ TSENG TAL YAA GH ++V L +KG ++K Q AL + G+ I L
Sbjct: 953 LDGTSENGMTALCYAAAAGHMKLVCLLTKKGVRVDHLDKKGQCALVHSALRGHGDILQYL 1012
Query: 99 ATAKGGKKP 107
T + P
Sbjct: 1013 LTCEWSPGP 1021
Score = 31.2 bits (69), Expect = 2.1
Identities = 16/49 (32%), Positives = 27/49 (55%)
Query: 18 CSAAEGDIAKLTGILSHSPSLLNETSENGWTALMYAARNGHPEIVQFLL 66
C AA KL +L+ ++ + G AL+++A GH +I+Q+LL
Sbjct: 965 CYAAAAGHMKLVCLLTKKGVRVDHLDKKGQCALVHSALRGHGDILQYLL 1013
>gi|225543461 tetratricopeptide repeat, ankyrin repeat and coiled-coil
containing 1 isoform 1 [Homo sapiens]
Length = 1861
Score = 53.9 bits (128), Expect = 3e-07
Identities = 50/176 (28%), Positives = 78/176 (44%), Gaps = 19/176 (10%)
Query: 14 TQFHCSAAEGDIAKLTGILSHSPSLLNETSENGWTALMYAARNGHPEIVQFLLEKGCDRS 73
T +A EG ++ + +LS +L + + G +AL +A GH +VQ+L+E+G
Sbjct: 1147 TPLMVAACEGHLSTVEFLLSKGAAL-SSLDKEGLSALSWACLKGHRAVVQYLVEEGAAID 1205
Query: 74 IVNKSRQTALDIAVFWGYKHIANLLATAKG---------GKKPWFLTNEVEECENYFSKT 124
+K+ +T LD+A F+G L KG G +P + C N
Sbjct: 1206 QTDKNGRTPLDLAAFYGDAETV-LYLVEKGAVIEHVDHSGMRP---LDRAIGCRNTSVVV 1261
Query: 125 LLDRKSEKRNNSDWLLAKESHPATVFILFSDL----NPLVTLGGNKESFQQPEVRL 176
L RK K N+ W +A S P + IL L N + G KE+ Q+ + L
Sbjct: 1262 ALLRKGAKLGNAAWAMA-TSKPDILIILLQKLMEEGNVMYKKGKMKEAAQRYQYAL 1316
Score = 45.4 bits (106), Expect = 1e-04
Identities = 26/78 (33%), Positives = 42/78 (53%), Gaps = 1/78 (1%)
Query: 14 TQFHCSAAEGDIAKLTGILSHSPSLLNETSENGWTALMYAARNGHPEIVQFLLEKGCDRS 73
T +A G + +L H ++ + T+ G L AAR GH +IV+ LLE+GCD +
Sbjct: 1081 TALTAAAGRGKLEVCELLLGHGAAV-SRTNRRGVPPLFCAARQGHWQIVRLLLERGCDVN 1139
Query: 74 IVNKSRQTALDIAVFWGY 91
+ +K +T L +A G+
Sbjct: 1140 LSDKQGRTPLMVAACEGH 1157
Score = 43.5 bits (101), Expect = 4e-04
Identities = 27/69 (39%), Positives = 36/69 (52%)
Query: 39 LNETSENGWTALMYAARNGHPEIVQFLLEKGCDRSIVNKSRQTALDIAVFWGYKHIANLL 98
L+ TSENG TAL YAA GH ++V L +KG ++K Q AL + G+ I L
Sbjct: 961 LDGTSENGMTALCYAAAAGHMKLVCLLTKKGVRVDHLDKKGQCALVHSALRGHGDILQYL 1020
Query: 99 ATAKGGKKP 107
T + P
Sbjct: 1021 LTCEWSPGP 1029
Score = 31.2 bits (69), Expect = 2.1
Identities = 16/49 (32%), Positives = 27/49 (55%)
Query: 18 CSAAEGDIAKLTGILSHSPSLLNETSENGWTALMYAARNGHPEIVQFLL 66
C AA KL +L+ ++ + G AL+++A GH +I+Q+LL
Sbjct: 973 CYAAAAGHMKLVCLLTKKGVRVDHLDKKGQCALVHSALRGHGDILQYLL 1021
>gi|50511945 cajalin 2 isoform a [Homo sapiens]
Length = 1248
Score = 53.9 bits (128), Expect = 3e-07
Identities = 30/87 (34%), Positives = 49/87 (56%), Gaps = 2/87 (2%)
Query: 17 HCSAAEGDIAKLTGILSHSPS--LLNETSENGWTALMYAARNGHPEIVQFLLEKGCDRSI 74
H +A +GD+ + ++ H PS +NE + TAL AA+ GH E+V LLE+ D +I
Sbjct: 97 HLAAWKGDVEIVKILIHHGPSHSRVNEQNNENETALHCAAQYGHSEVVAVLLEELTDPTI 156
Query: 75 VNKSRQTALDIAVFWGYKHIANLLATA 101
N +T LD+A +G + ++ +A
Sbjct: 157 RNSKLETPLDLAALYGRLRVVKMIISA 183
Score = 38.1 bits (87), Expect = 0.017
Identities = 28/90 (31%), Positives = 43/90 (47%), Gaps = 1/90 (1%)
Query: 11 EIVTQFHCSAAEGDIAKLTGILSHSPSLLNETSENGWTALMYAARNGHPEIVQFLLEKGC 70
++ T +A G + + I+S P+L++ + T L AARNGH +VQ LLE G
Sbjct: 160 KLETPLDLAALYGRLRVVKMIISAHPNLMSCNTRKH-TPLHLAARNGHKAVVQVLLEAGM 218
Query: 71 DRSIVNKSRQTALDIAVFWGYKHIANLLAT 100
D S + + A+F + LL T
Sbjct: 219 DVSCQTEKGSALHEAALFGKVDVVRVLLET 248
Score = 35.4 bits (80), Expect = 0.11
Identities = 19/60 (31%), Positives = 32/60 (53%)
Query: 39 LNETSENGWTALMYAARNGHPEIVQFLLEKGCDRSIVNKSRQTALDIAVFWGYKHIANLL 98
+N T +G+TAL +AA NGH +IV LL+ ++ + + +A + G I +L
Sbjct: 52 VNCTDSSGYTALHHAALNGHKDIVLKLLQYEASTNVADNKGYFPIHLAAWKGDVEIVKIL 111
Score = 32.3 bits (72), Expect = 0.93
Identities = 25/88 (28%), Positives = 39/88 (44%), Gaps = 4/88 (4%)
Query: 14 TQFHCSAAEGDIAKLTGILSHSPSLLNETSENGWTALMYAARNGHPEIVQFLLEKGCDRS 73
T H +A G + +L + S N G+ + AA G EIV+ L+ G S
Sbjct: 61 TALHHAALNGHKDIVLKLLQYEAST-NVADNKGYFPIHLAAWKGDVEIVKILIHHGPSHS 119
Query: 74 IVNK---SRQTALDIAVFWGYKHIANLL 98
VN+ +TAL A +G+ + +L
Sbjct: 120 RVNEQNNENETALHCAAQYGHSEVVAVL 147
Score = 32.0 bits (71), Expect = 1.2
Identities = 23/72 (31%), Positives = 36/72 (50%), Gaps = 2/72 (2%)
Query: 14 TQFHCSAAEGDIAKLTGILSHSPSLLNETSENGWTALMYAARNGHPEIVQFLLEKGCDRS 73
T H +A G A + +L + +T + +AL AA G ++V+ LLE G D +
Sbjct: 196 TPLHLAARNGHKAVVQVLLEAGMDVSCQTEKG--SALHEAALFGKVDVVRVLLETGIDAN 253
Query: 74 IVNKSRQTALDI 85
I + +T LDI
Sbjct: 254 IKDSLGRTVLDI 265
>gi|19924156 regulatory factor X-associated ankyrin-containing
protein isoform b [Homo sapiens]
Length = 237
Score = 50.8 bits (120), Expect = 3e-06
Identities = 27/62 (43%), Positives = 39/62 (62%)
Query: 37 SLLNETSENGWTALMYAARNGHPEIVQFLLEKGCDRSIVNKSRQTALDIAVFWGYKHIAN 96
+L+N+ E G+T L++A+ G E V+FLLE G D I+ K R++AL +A GY I
Sbjct: 92 NLVNKPDERGFTPLIWASAFGEIETVRFLLEWGADPHILAKERESALSLASTGGYTDIVG 151
Query: 97 LL 98
LL
Sbjct: 152 LL 153
Score = 46.6 bits (109), Expect = 5e-05
Identities = 25/79 (31%), Positives = 40/79 (50%)
Query: 20 AAEGDIAKLTGILSHSPSLLNETSENGWTALMYAARNGHPEIVQFLLEKGCDRSIVNKSR 79
A+ G + G+L +N NG T L+YA R H + V+ LL +G D + S
Sbjct: 141 ASTGGYTDIVGLLLERDVDINIYDWNGGTPLLYAVRGNHVKCVEALLARGADLTTEADSG 200
Query: 80 QTALDIAVFWGYKHIANLL 98
T +D+AV GY+ + ++
Sbjct: 201 YTPMDLAVALGYRKVQQVI 219
>gi|148596917 fibronectin type III and ankyrin repeat domains 1
[Homo sapiens]
Length = 345
Score = 50.4 bits (119), Expect = 3e-06
Identities = 29/89 (32%), Positives = 49/89 (55%), Gaps = 1/89 (1%)
Query: 19 SAAEGDIAKLTGILSHSPSLLNETSENGWTALMYAARNGHPEIVQFLLEKGCDRSIVNKS 78
SA G+ ++ +L + + +N NG T LM A N H E+VQ LL+KG D S+ N+
Sbjct: 252 SAVSGN-QRVASLLIDAGANVNVKDRNGKTPLMVAVLNNHEELVQLLLDKGADASVKNEF 310
Query: 79 RQTALDIAVFWGYKHIANLLATAKGGKKP 107
+ L++A + + + +LL K ++P
Sbjct: 311 GKGVLEMARVFDRQSVVSLLEERKKKQRP 339
Score = 38.9 bits (89), Expect = 0.010
Identities = 23/82 (28%), Positives = 43/82 (52%)
Query: 17 HCSAAEGDIAKLTGILSHSPSLLNETSENGWTALMYAARNGHPEIVQFLLEKGCDRSIVN 76
H + + D L IL ++ ++ G+TALM AA+ G+ +V+ L+ G D ++ N
Sbjct: 115 HRAVSVNDEDLLVRILQGGRVKVDVPNKFGFTALMVAAQKGYTRLVKILVSNGTDVNLKN 174
Query: 77 KSRQTALDIAVFWGYKHIANLL 98
S + +L +A + G+ + L
Sbjct: 175 GSGKDSLMLACYAGHLDVVKYL 196
Score = 33.1 bits (74), Expect = 0.55
Identities = 16/58 (27%), Positives = 33/58 (56%), Gaps = 2/58 (3%)
Query: 46 GWTALMYAARNGHPEIVQFLLEKGCDRSIVNKSR--QTALDIAVFWGYKHIANLLATA 101
G TAL +AA GH +++++++ GC+ +V+ + ++ G + +A+LL A
Sbjct: 210 GCTALHWAADGGHCSVIEWMIKDGCEVDVVDTGSGWTPLMRVSAVSGNQRVASLLIDA 267
>gi|32967601 ankyrin 3 isoform 1 [Homo sapiens]
Length = 4377
Score = 50.4 bits (119), Expect = 3e-06
Identities = 27/85 (31%), Positives = 49/85 (57%), Gaps = 1/85 (1%)
Query: 14 TQFHCSAAEGDIAKLTGILSHSPSLLNETSENGWTALMYAARNGHPEIVQFLLEKGCDRS 73
T H ++ G A++ +L + + +N S+NG+T L AA+ H E+V+FLL+ G +S
Sbjct: 109 TALHIASLAGQ-AEVVKVLVTNGANVNAQSQNGFTPLYMAAQENHLEVVKFLLDNGASQS 167
Query: 74 IVNKSRQTALDIAVFWGYKHIANLL 98
+ + T L +A+ G+ + +LL
Sbjct: 168 LATEDGFTPLAVALQQGHDQVVSLL 192
Score = 48.9 bits (115), Expect = 1e-05
Identities = 30/85 (35%), Positives = 42/85 (49%), Gaps = 1/85 (1%)
Query: 14 TQFHCSAAEGDIAKLTGILSHSPSLLNETSENGWTALMYAARNGHPEIVQFLLEKGCDRS 73
T H SA G + +L S N + +G+T L +AR GH ++ FLL+ G S
Sbjct: 501 TPLHISARLGKADIVQQLLQQGASP-NAATTSGYTPLHLSAREGHEDVAAFLLDHGASLS 559
Query: 74 IVNKSRQTALDIAVFWGYKHIANLL 98
I K T L +A +G +ANLL
Sbjct: 560 ITTKKGFTPLHVAAKYGKLEVANLL 584
Score = 46.2 bits (108), Expect = 6e-05
Identities = 46/153 (30%), Positives = 66/153 (43%), Gaps = 17/153 (11%)
Query: 14 TQFHCSAAEGDIAKLTGILSHSPSLLNETSENGWTALMYAARNGHPEIVQFLLEKGCDRS 73
T H SA EG +L H SL + T++ G+T L AA+ G E+ LL+K
Sbjct: 534 TPLHLSAREGHEDVAAFLLDHGASL-SITTKKGFTPLHVAAKYGKLEVANLLLQKSASPD 592
Query: 74 IVNKSRQTALDIAVFWGYKHIANLL--------ATAKGGKKPWFLTNEVEECENYFSKTL 125
KS T L +A + + +A LL A AK G P + + + + + TL
Sbjct: 593 AAGKSGLTPLHVAAHYDNQKVALLLLDQGASPHAAAKNGYTPLHIAAKKNQMD--IATTL 650
Query: 126 L----DRKSEKRNN--SDWLLAKESHPATVFIL 152
L D + R S L A+E H V +L
Sbjct: 651 LEYGADANAVTRQGIASVHLAAQEGHVDMVSLL 683
Score = 44.3 bits (103), Expect = 2e-04
Identities = 27/85 (31%), Positives = 42/85 (49%), Gaps = 1/85 (1%)
Query: 14 TQFHCSAAEGDIAKLTGILSHSPSLLNETSENGWTALMYAARNGHPEIVQFLLEKGCDRS 73
T H G+I + +L HS + N ++NG+T L AA+ GH I+ LL+ +
Sbjct: 732 TPLHVGCHYGNIKIVNFLLQHSAKV-NAKTKNGYTPLHQAAQQGHTHIINVLLQNNASPN 790
Query: 74 IVNKSRQTALDIAVFWGYKHIANLL 98
+ + TAL IA GY + + L
Sbjct: 791 ELTVNGNTALGIARRLGYISVVDTL 815
Score = 42.7 bits (99), Expect = 7e-04
Identities = 28/86 (32%), Positives = 43/86 (50%), Gaps = 1/86 (1%)
Query: 13 VTQFHCSAAEGDIAKLTGILSHSPSLLNETSENGWTALMYAARNGHPEIVQFLLEKGCDR 72
+T H +A G + ++ ++ H S N T+ G TAL AAR+G E+V++L++ G
Sbjct: 434 LTPIHVAAFMGHVNIVSQLMHHGASP-NTTNVRGETALHMAARSGQAEVVRYLVQDGAQV 492
Query: 73 SIVNKSRQTALDIAVFWGYKHIANLL 98
K QT L I+ G I L
Sbjct: 493 EAKAKDDQTPLHISARLGKADIVQQL 518
Score = 40.8 bits (94), Expect = 0.003
Identities = 26/95 (27%), Positives = 43/95 (45%), Gaps = 1/95 (1%)
Query: 6 RSLKQEIVTQFHCSAAEGDIAKLTGILSHSPSLLNETSENGWTALMYAARNGHPEIVQFL 65
R K + + +A G + K + + + N ++NG AL A++ GH E+V L
Sbjct: 35 RKKKSDANASYLRAARAGHLEKALDYIKNGVDI-NICNQNGLNALHLASKEGHVEVVSEL 93
Query: 66 LEKGCDRSIVNKSRQTALDIAVFWGYKHIANLLAT 100
L++ + K TAL IA G + +L T
Sbjct: 94 LQREANVDAATKKGNTALHIASLAGQAEVVKVLVT 128
Score = 40.0 bits (92), Expect = 0.004
Identities = 26/90 (28%), Positives = 41/90 (45%), Gaps = 1/90 (1%)
Query: 13 VTQFHCSAAEGDIAKLTGILSHSPSLLNETSENGWTALMYAARNGHPEIVQFLLEKGCDR 72
+T HC A G + +L + +L++T +NG + L A + H VQ LL+
Sbjct: 302 LTPLHCGARSGHEQVVEMLLDRAAPILSKT-KNGLSPLHMATQGDHLNCVQLLLQHNVPV 360
Query: 73 SIVNKSRQTALDIAVFWGYKHIANLLATAK 102
V TAL +A G+ +A +L K
Sbjct: 361 DDVTNDYLTALHVAAHCGHYKVAKVLLDKK 390
Score = 35.8 bits (81), Expect = 0.084
Identities = 24/85 (28%), Positives = 37/85 (43%), Gaps = 1/85 (1%)
Query: 14 TQFHCSAAEGDIAKLTGILSHSPSLLNETSENGWTALMYAARNGHPEIVQFLLEKGCDRS 73
T H + + I + +L H S+ +E+G T + AA GH IV L+ G +
Sbjct: 402 TPLHIACKKNRIKVMELLLKHGASI-QAVTESGLTPIHVAAFMGHVNIVSQLMHHGASPN 460
Query: 74 IVNKSRQTALDIAVFWGYKHIANLL 98
N +TAL +A G + L
Sbjct: 461 TTNVRGETALHMAARSGQAEVVRYL 485
Score = 35.8 bits (81), Expect = 0.084
Identities = 24/86 (27%), Positives = 42/86 (48%), Gaps = 1/86 (1%)
Query: 13 VTQFHCSAAEGDIAKLTGILSHSPSLLNETSENGWTALMYAARNGHPEIVQFLLEKGCDR 72
+T H +A E D + +L + + ++ ++ G+T L G+ +IV FLL+
Sbjct: 698 LTPLHLAAQE-DRVNVAEVLVNQGAHVDAQTKMGYTPLHVGCHYGNIKIVNFLLQHSAKV 756
Query: 73 SIVNKSRQTALDIAVFWGYKHIANLL 98
+ K+ T L A G+ HI N+L
Sbjct: 757 NAKTKNGYTPLHQAAQQGHTHIINVL 782
Score = 34.3 bits (77), Expect = 0.24
Identities = 22/85 (25%), Positives = 41/85 (48%), Gaps = 1/85 (1%)
Query: 14 TQFHCSAAEGDIAKLTGILSHSPSLLNETSENGWTALMYAARNGHPEIVQFLLEKGCDRS 73
T H +A + + T +L + N + G ++ AA+ GH ++V LL + + +
Sbjct: 633 TPLHIAAKKNQMDIATTLLEYGADA-NAVTRQGIASVHLAAQEGHVDMVSLLLGRNANVN 691
Query: 74 IVNKSRQTALDIAVFWGYKHIANLL 98
+ NKS T L +A ++A +L
Sbjct: 692 LSNKSGLTPLHLAAQEDRVNVAEVL 716
Score = 29.3 bits (64), Expect = 7.9
Identities = 23/73 (31%), Positives = 34/73 (46%), Gaps = 5/73 (6%)
Query: 14 TQFHCSAAEGDIAKLTGILSHSPSLLNETSENGWTALMYAARNGHPEIVQFLLEKGCDRS 73
T + +A E + + +L + S T E+G+T L A + GH ++V LLE
Sbjct: 142 TPLYMAAQENHLEVVKFLLDNGASQSLAT-EDGFTPLAVALQQGHDQVVSLLLE----ND 196
Query: 74 IVNKSRQTALDIA 86
K R AL IA
Sbjct: 197 TKGKVRLPALHIA 209
>gi|140161500 ankyrin repeat and sterile alpha motif domain
containing 1 [Homo sapiens]
Length = 1134
Score = 50.1 bits (118), Expect = 4e-06
Identities = 31/88 (35%), Positives = 51/88 (57%), Gaps = 4/88 (4%)
Query: 17 HCSAAEGDIAKLTGILSH---SPSLLNETSENGWTALMYAARNGHPEIVQFLLEKGCDRS 73
H +A +GD A++ +L H S + +NE + + TAL AA+ GH E+V+ LLE+ D +
Sbjct: 118 HLAAWKGD-AQIVRLLIHQGPSHTRVNEQNNDNETALHCAAQYGHTEVVKVLLEELTDPT 176
Query: 74 IVNKSRQTALDIAVFWGYKHIANLLATA 101
+ N +T LD+A +G + +L A
Sbjct: 177 MRNNKFETPLDLAALYGRLEVVKMLLNA 204
Score = 37.0 bits (84), Expect = 0.038
Identities = 28/88 (31%), Positives = 43/88 (48%), Gaps = 2/88 (2%)
Query: 14 TQFHCSAAEGDIAKLTGILSHSPSLLNETSENGWTALMYAARNGHPEIVQFLLEKGCDRS 73
T +A G + + +L+ P+LL+ ++ T L AARNGH +VQ LL+ G D S
Sbjct: 184 TPLDLAALYGRLEVVKMLLNAHPNLLSCNTKKH-TPLHLAARNGHKAVVQVLLDAGMD-S 241
Query: 74 IVNKSRQTALDIAVFWGYKHIANLLATA 101
+AL A +G + +L A
Sbjct: 242 NYQTEMGSALHEAALFGKTDVVQILLAA 269
Score = 33.1 bits (74), Expect = 0.55
Identities = 18/60 (30%), Positives = 29/60 (48%)
Query: 39 LNETSENGWTALMYAARNGHPEIVQFLLEKGCDRSIVNKSRQTALDIAVFWGYKHIANLL 98
+N G+T L +AA NGH ++V+ LL ++ + L +A + G I LL
Sbjct: 73 VNCVDSTGYTPLHHAALNGHKDVVEVLLRNDALTNVADSKGCYPLHLAAWKGDAQIVRLL 132
>gi|46519154 ankyrin repeat and KH domain containing 1 isoform 3
[Homo sapiens]
Length = 627
Score = 50.1 bits (118), Expect = 4e-06
Identities = 29/83 (34%), Positives = 47/83 (56%), Gaps = 1/83 (1%)
Query: 20 AAEGDIAKLTGILSHSPSLLNETSENGWTALMYAARNGHPEIVQFLLEKGCD-RSIVNKS 78
AA G +L +L + L E ++ G+T LM AAR GH E+V LL +G + + ++
Sbjct: 445 AACGGHVELAALLIERGANLEEVNDEGYTPLMEAAREGHEEMVALLLAQGANINAQTEET 504
Query: 79 RQTALDIAVFWGYKHIANLLATA 101
++TAL +A G+ +A+ L A
Sbjct: 505 QETALTLACCGGFSEVADFLIKA 527
Score = 41.2 bits (95), Expect = 0.002
Identities = 24/83 (28%), Positives = 43/83 (51%), Gaps = 1/83 (1%)
Query: 20 AAEGDIAKLTGILSHSPSLLNETSENGWTALMYAARNGHPEIVQFLLEKGCD-RSIVNKS 78
A G + +L + + + + +ENG T LM AA GH E+ + LL+ G + N+
Sbjct: 312 ACAGGFVDIVKVLLNEGANIEDHNENGHTPLMEAASAGHVEVARVLLDHGAGINTHSNEF 371
Query: 79 RQTALDIAVFWGYKHIANLLATA 101
+++AL +A + G+ + L A
Sbjct: 372 KESALTLACYKGHLDMVRFLLEA 394
Score = 41.2 bits (95), Expect = 0.002
Identities = 25/80 (31%), Positives = 39/80 (48%)
Query: 19 SAAEGDIAKLTGILSHSPSLLNETSENGWTALMYAARNGHPEIVQFLLEKGCDRSIVNKS 78
+A+ G + +L H + ++E +AL A GH ++V+FLLE G D+
Sbjct: 345 AASAGHVEVARVLLDHGAGINTHSNEFKESALTLACYKGHLDMVRFLLEAGADQEHKTDE 404
Query: 79 RQTALDIAVFWGYKHIANLL 98
TAL A G+ +A LL
Sbjct: 405 MHTALMEACMDGHVEVARLL 424
Score = 36.6 bits (83), Expect = 0.049
Identities = 27/75 (36%), Positives = 38/75 (50%), Gaps = 3/75 (4%)
Query: 24 DIAKLTGILSHSPSLLNETSENGWTALMYAARNGHPEIVQFLLEKGCDRSIVNKSRQTAL 83
DI KL +L H + N S G TAL YA G +IV+ LL +G + N++ T L
Sbjct: 286 DIVKL--LLLHDADV-NSQSATGNTALTYACAGGFVDIVKVLLNEGANIEDHNENGHTPL 342
Query: 84 DIAVFWGYKHIANLL 98
A G+ +A +L
Sbjct: 343 MEAASAGHVEVARVL 357
Score = 34.7 bits (78), Expect = 0.19
Identities = 19/54 (35%), Positives = 30/54 (55%)
Query: 48 TALMYAARNGHPEIVQFLLEKGCDRSIVNKSRQTALDIAVFWGYKHIANLLATA 101
T LM A++ GH E+V++LL G + + TAL A G+ +A++L A
Sbjct: 537 TPLMEASQEGHLELVKYLLASGANVHATTATGDTALTYACENGHTDVADVLLQA 590
Score = 34.7 bits (78), Expect = 0.19
Identities = 19/53 (35%), Positives = 30/53 (56%), Gaps = 1/53 (1%)
Query: 19 SAAEGDIAKLTGILSHSPSLLNETSENGWTALMYAARNGHPEIVQFLLEKGCD 71
++ EG + +L L S + ++ T+ G TAL YA NGH ++ LL+ G D
Sbjct: 542 ASQEGHL-ELVKYLLASGANVHATTATGDTALTYACENGHTDVADVLLQAGAD 593
Score = 34.3 bits (77), Expect = 0.24
Identities = 18/51 (35%), Positives = 29/51 (56%)
Query: 48 TALMYAARNGHPEIVQFLLEKGCDRSIVNKSRQTALDIAVFWGYKHIANLL 98
TALM A +GH E+ + LL+ G ++ S ++ L +A G+ +A LL
Sbjct: 407 TALMEACMDGHVEVARLLLDSGAQVNMPADSFESPLTLAACGGHVELAALL 457
Score = 31.6 bits (70), Expect = 1.6
Identities = 23/81 (28%), Positives = 39/81 (48%), Gaps = 3/81 (3%)
Query: 18 CSAAEGDIAKLTGILSHSPSLLNETSENGWTALMYAARNGHPEIVQFLLEKGCDRSIVNK 77
C ++A+L L S + +N +++ + L AA GH E+ L+E+G + VN
Sbjct: 413 CMDGHVEVARL---LLDSGAQVNMPADSFESPLTLAACGGHVELAALLIERGANLEEVND 469
Query: 78 SRQTALDIAVFWGYKHIANLL 98
T L A G++ + LL
Sbjct: 470 EGYTPLMEAAREGHEEMVALL 490
Score = 30.0 bits (66), Expect = 4.6
Identities = 27/83 (32%), Positives = 38/83 (45%), Gaps = 6/83 (7%)
Query: 19 SAAEGDIAKLTGILSHSPSLLNETSENGWTALMYAARNGHPEIVQFLLEKGC---DRSIV 75
+ ++GD+ + +L S+ NE +E G + L A G+ E+ Q LL DR
Sbjct: 212 ACSDGDVNAVRKLLDEGRSV-NEHTEEGESLLCLACSAGYYELAQVLLAMHANVEDRG-- 268
Query: 76 NKSRQTALDIAVFWGYKHIANLL 98
NK T L A GY I LL
Sbjct: 269 NKGDITPLMAASSGGYLDIVKLL 291
Score = 30.0 bits (66), Expect = 4.6
Identities = 19/76 (25%), Positives = 35/76 (46%), Gaps = 6/76 (7%)
Query: 19 SAAEGDIAKLTGILSHSPSLLNETSENGWTALMYAARNGHPEIVQFLL------EKGCDR 72
+A EG + +L+ ++ +T E TAL A G E+ FL+ E GC
Sbjct: 478 AAREGHEEMVALLLAQGANINAQTEETQETALTLACCGGFSEVADFLIKAGADIELGCST 537
Query: 73 SIVNKSRQTALDIAVF 88
++ S++ L++ +
Sbjct: 538 PLMEASQEGHLELVKY 553
>gi|46519151 ankyrin repeat and KH domain containing 1 isoform 2
[Homo sapiens]
Length = 616
Score = 50.1 bits (118), Expect = 4e-06
Identities = 29/83 (34%), Positives = 47/83 (56%), Gaps = 1/83 (1%)
Query: 20 AAEGDIAKLTGILSHSPSLLNETSENGWTALMYAARNGHPEIVQFLLEKGCD-RSIVNKS 78
AA G +L +L + L E ++ G+T LM AAR GH E+V LL +G + + ++
Sbjct: 434 AACGGHVELAALLIERGANLEEVNDEGYTPLMEAAREGHEEMVALLLAQGANINAQTEET 493
Query: 79 RQTALDIAVFWGYKHIANLLATA 101
++TAL +A G+ +A+ L A
Sbjct: 494 QETALTLACCGGFSEVADFLIKA 516
Score = 41.2 bits (95), Expect = 0.002
Identities = 24/83 (28%), Positives = 43/83 (51%), Gaps = 1/83 (1%)
Query: 20 AAEGDIAKLTGILSHSPSLLNETSENGWTALMYAARNGHPEIVQFLLEKGCD-RSIVNKS 78
A G + +L + + + + +ENG T LM AA GH E+ + LL+ G + N+
Sbjct: 301 ACAGGFVDIVKVLLNEGANIEDHNENGHTPLMEAASAGHVEVARVLLDHGAGINTHSNEF 360
Query: 79 RQTALDIAVFWGYKHIANLLATA 101
+++AL +A + G+ + L A
Sbjct: 361 KESALTLACYKGHLDMVRFLLEA 383
Score = 41.2 bits (95), Expect = 0.002
Identities = 25/80 (31%), Positives = 39/80 (48%)
Query: 19 SAAEGDIAKLTGILSHSPSLLNETSENGWTALMYAARNGHPEIVQFLLEKGCDRSIVNKS 78
+A+ G + +L H + ++E +AL A GH ++V+FLLE G D+
Sbjct: 334 AASAGHVEVARVLLDHGAGINTHSNEFKESALTLACYKGHLDMVRFLLEAGADQEHKTDE 393
Query: 79 RQTALDIAVFWGYKHIANLL 98
TAL A G+ +A LL
Sbjct: 394 MHTALMEACMDGHVEVARLL 413
Score = 36.6 bits (83), Expect = 0.049
Identities = 27/75 (36%), Positives = 38/75 (50%), Gaps = 3/75 (4%)
Query: 24 DIAKLTGILSHSPSLLNETSENGWTALMYAARNGHPEIVQFLLEKGCDRSIVNKSRQTAL 83
DI KL +L H + N S G TAL YA G +IV+ LL +G + N++ T L
Sbjct: 275 DIVKL--LLLHDADV-NSQSATGNTALTYACAGGFVDIVKVLLNEGANIEDHNENGHTPL 331
Query: 84 DIAVFWGYKHIANLL 98
A G+ +A +L
Sbjct: 332 MEAASAGHVEVARVL 346
Score = 34.7 bits (78), Expect = 0.19
Identities = 19/54 (35%), Positives = 30/54 (55%)
Query: 48 TALMYAARNGHPEIVQFLLEKGCDRSIVNKSRQTALDIAVFWGYKHIANLLATA 101
T LM A++ GH E+V++LL G + + TAL A G+ +A++L A
Sbjct: 526 TPLMEASQEGHLELVKYLLASGANVHATTATGDTALTYACENGHTDVADVLLQA 579
Score = 34.7 bits (78), Expect = 0.19
Identities = 19/53 (35%), Positives = 30/53 (56%), Gaps = 1/53 (1%)
Query: 19 SAAEGDIAKLTGILSHSPSLLNETSENGWTALMYAARNGHPEIVQFLLEKGCD 71
++ EG + +L L S + ++ T+ G TAL YA NGH ++ LL+ G D
Sbjct: 531 ASQEGHL-ELVKYLLASGANVHATTATGDTALTYACENGHTDVADVLLQAGAD 582
Score = 34.3 bits (77), Expect = 0.24
Identities = 18/51 (35%), Positives = 29/51 (56%)
Query: 48 TALMYAARNGHPEIVQFLLEKGCDRSIVNKSRQTALDIAVFWGYKHIANLL 98
TALM A +GH E+ + LL+ G ++ S ++ L +A G+ +A LL
Sbjct: 396 TALMEACMDGHVEVARLLLDSGAQVNMPADSFESPLTLAACGGHVELAALL 446
Score = 31.6 bits (70), Expect = 1.6
Identities = 23/81 (28%), Positives = 39/81 (48%), Gaps = 3/81 (3%)
Query: 18 CSAAEGDIAKLTGILSHSPSLLNETSENGWTALMYAARNGHPEIVQFLLEKGCDRSIVNK 77
C ++A+L L S + +N +++ + L AA GH E+ L+E+G + VN
Sbjct: 402 CMDGHVEVARL---LLDSGAQVNMPADSFESPLTLAACGGHVELAALLIERGANLEEVND 458
Query: 78 SRQTALDIAVFWGYKHIANLL 98
T L A G++ + LL
Sbjct: 459 EGYTPLMEAAREGHEEMVALL 479
Score = 30.0 bits (66), Expect = 4.6
Identities = 27/83 (32%), Positives = 38/83 (45%), Gaps = 6/83 (7%)
Query: 19 SAAEGDIAKLTGILSHSPSLLNETSENGWTALMYAARNGHPEIVQFLLEKGC---DRSIV 75
+ ++GD+ + +L S+ NE +E G + L A G+ E+ Q LL DR
Sbjct: 201 ACSDGDVNAVRKLLDEGRSV-NEHTEEGESLLCLACSAGYYELAQVLLAMHANVEDRG-- 257
Query: 76 NKSRQTALDIAVFWGYKHIANLL 98
NK T L A GY I LL
Sbjct: 258 NKGDITPLMAASSGGYLDIVKLL 280
Score = 30.0 bits (66), Expect = 4.6
Identities = 19/76 (25%), Positives = 35/76 (46%), Gaps = 6/76 (7%)
Query: 19 SAAEGDIAKLTGILSHSPSLLNETSENGWTALMYAARNGHPEIVQFLL------EKGCDR 72
+A EG + +L+ ++ +T E TAL A G E+ FL+ E GC
Sbjct: 467 AAREGHEEMVALLLAQGANINAQTEETQETALTLACCGGFSEVADFLIKAGADIELGCST 526
Query: 73 SIVNKSRQTALDIAVF 88
++ S++ L++ +
Sbjct: 527 PLMEASQEGHLELVKY 542
>gi|46519147 ankyrin repeat and KH domain containing 1 isoform 1
[Homo sapiens]
Length = 2542
Score = 50.1 bits (118), Expect = 4e-06
Identities = 29/83 (34%), Positives = 47/83 (56%), Gaps = 1/83 (1%)
Query: 20 AAEGDIAKLTGILSHSPSLLNETSENGWTALMYAARNGHPEIVQFLLEKGCD-RSIVNKS 78
AA G +L +L + L E ++ G+T LM AAR GH E+V LL +G + + ++
Sbjct: 445 AACGGHVELAALLIERGANLEEVNDEGYTPLMEAAREGHEEMVALLLAQGANINAQTEET 504
Query: 79 RQTALDIAVFWGYKHIANLLATA 101
++TAL +A G+ +A+ L A
Sbjct: 505 QETALTLACCGGFSEVADFLIKA 527
Score = 43.9 bits (102), Expect = 3e-04
Identities = 30/86 (34%), Positives = 45/86 (52%), Gaps = 3/86 (3%)
Query: 20 AAEGDIAKLTGILSHSPSLLNET--SENGWTALMYAARNGHPEIVQFLLEKGCD-RSIVN 76
AA G + IL ++ + +N S+ G + LM AA NGH V+ LL+ G D + +
Sbjct: 1162 AASGGYVNIIKILLNAGAEINSRTGSKLGISPLMLAAMNGHVPAVKLLLDMGSDINAQIE 1221
Query: 77 KSRQTALDIAVFWGYKHIANLLATAK 102
+R TAL +A F G + +LL K
Sbjct: 1222 TNRNTALTLACFQGRAEVVSLLLDRK 1247
Score = 41.2 bits (95), Expect = 0.002
Identities = 24/83 (28%), Positives = 43/83 (51%), Gaps = 1/83 (1%)
Query: 20 AAEGDIAKLTGILSHSPSLLNETSENGWTALMYAARNGHPEIVQFLLEKGCD-RSIVNKS 78
A G + +L + + + + +ENG T LM AA GH E+ + LL+ G + N+
Sbjct: 312 ACAGGFVDIVKVLLNEGANIEDHNENGHTPLMEAASAGHVEVARVLLDHGAGINTHSNEF 371
Query: 79 RQTALDIAVFWGYKHIANLLATA 101
+++AL +A + G+ + L A
Sbjct: 372 KESALTLACYKGHLDMVRFLLEA 394
Score = 41.2 bits (95), Expect = 0.002
Identities = 25/80 (31%), Positives = 39/80 (48%)
Query: 19 SAAEGDIAKLTGILSHSPSLLNETSENGWTALMYAARNGHPEIVQFLLEKGCDRSIVNKS 78
+A+ G + +L H + ++E +AL A GH ++V+FLLE G D+
Sbjct: 345 AASAGHVEVARVLLDHGAGINTHSNEFKESALTLACYKGHLDMVRFLLEAGADQEHKTDE 404
Query: 79 RQTALDIAVFWGYKHIANLL 98
TAL A G+ +A LL
Sbjct: 405 MHTALMEACMDGHVEVARLL 424
Score = 40.4 bits (93), Expect = 0.003
Identities = 26/88 (29%), Positives = 45/88 (51%), Gaps = 2/88 (2%)
Query: 20 AAEGDIAKLTGILSHSPSLLNETSENGWTALMYAARNGHPEIVQFLLEKGCD-RSIVNKS 78
A G +L +L + + + G+T L+ AA GH +V+ LL+KG D + ++
Sbjct: 1062 ACAGGHEELVSVLIARDAKIEHRDKKGFTPLILAATAGHVGVVEILLDKGGDIEAQSERT 1121
Query: 79 RQTALDIAVFWGYKHIANLLATAKGGKK 106
+ T L +A G + + +LL A+G K
Sbjct: 1122 KDTPLSLACSGGRQEVVDLL-LARGANK 1148
Score = 39.7 bits (91), Expect = 0.006
Identities = 30/98 (30%), Positives = 44/98 (44%), Gaps = 11/98 (11%)
Query: 26 AKLTGILSHSPSLLNETSENGWTALMYAARNGHPEIVQFLLEKGCDRSI--VNKSRQTAL 83
A++ +L + + ++ G T LM AA G+ E+ + LL+KG D + V SR TAL
Sbjct: 1237 AEVVSLLLDRKANVEHRAKTGLTPLMEAASGGYAEVGRVLLDKGADVNAPPVPSSRDTAL 1296
Query: 84 DIAVFWGYKHIANLL---------ATAKGGKKPWFLTN 112
IA G+ LL KG W +N
Sbjct: 1297 TIAADKGHYKFCELLIHRGAHIDVRNKKGNTPLWLASN 1334
Score = 39.3 bits (90), Expect = 0.008
Identities = 31/94 (32%), Positives = 43/94 (45%), Gaps = 13/94 (13%)
Query: 17 HCSAAEGDIA----------KLTGILSHSPSLLNETSENGWTALMYAARNGHPEIVQFLL 66
H + A GD A + +L + + L SE G T LM AAR GH VQFL+
Sbjct: 562 HATTATGDTALTYACENGHTDVADVLLQAGADLEHESEGGRTPLMKAARAGHLCTVQFLI 621
Query: 67 EKGC--DRSIVNKSRQTALDIAVFWGYKHIANLL 98
KG +R+ N T + +A G+ + LL
Sbjct: 622 SKGANVNRATANND-HTVVSLACAGGHLAVVELL 654
Score = 36.6 bits (83), Expect = 0.049
Identities = 27/75 (36%), Positives = 38/75 (50%), Gaps = 3/75 (4%)
Query: 24 DIAKLTGILSHSPSLLNETSENGWTALMYAARNGHPEIVQFLLEKGCDRSIVNKSRQTAL 83
DI KL +L H + N S G TAL YA G +IV+ LL +G + N++ T L
Sbjct: 286 DIVKL--LLLHDADV-NSQSATGNTALTYACAGGFVDIVKVLLNEGANIEDHNENGHTPL 342
Query: 84 DIAVFWGYKHIANLL 98
A G+ +A +L
Sbjct: 343 MEAASAGHVEVARVL 357
Score = 35.4 bits (80), Expect = 0.11
Identities = 22/68 (32%), Positives = 35/68 (51%), Gaps = 8/68 (11%)
Query: 48 TALMYAARNGHPEIVQFLLEKGCDRSIVNKSRQTALDIAVFWGYKHIANLLATA------ 101
T LM A++ GH E+V++LL G + + TAL A G+ +A++L A
Sbjct: 537 TPLMEASQEGHLELVKYLLASGANVHATTATGDTALTYACENGHTDVADVLLQAGADLEH 596
Query: 102 --KGGKKP 107
+GG+ P
Sbjct: 597 ESEGGRTP 604
Score = 35.4 bits (80), Expect = 0.11
Identities = 21/65 (32%), Positives = 35/65 (53%), Gaps = 1/65 (1%)
Query: 19 SAAEGDIAKLTGILSHSPSLLNETSENGWTALMYAARNGHPEIVQFLLEKGCDRSIVNKS 78
++ EG + +L L S + ++ T+ G TAL YA NGH ++ LL+ G D ++
Sbjct: 542 ASQEGHL-ELVKYLLASGANVHATTATGDTALTYACENGHTDVADVLLQAGADLEHESEG 600
Query: 79 RQTAL 83
+T L
Sbjct: 601 GRTPL 605
Score = 35.4 bits (80), Expect = 0.11
Identities = 22/83 (26%), Positives = 36/83 (43%)
Query: 19 SAAEGDIAKLTGILSHSPSLLNETSENGWTALMYAARNGHPEIVQFLLEKGCDRSIVNKS 78
+A G + + +L + ++ T L A G E+V LL +G ++ N S
Sbjct: 1095 AATAGHVGVVEILLDKGGDIEAQSERTKDTPLSLACSGGRQEVVDLLLARGANKEHRNVS 1154
Query: 79 RQTALDIAVFWGYKHIANLLATA 101
T L +A GY +I +L A
Sbjct: 1155 DYTPLSLAASGGYVNIIKILLNA 1177
Score = 34.3 bits (77), Expect = 0.24
Identities = 18/51 (35%), Positives = 29/51 (56%)
Query: 48 TALMYAARNGHPEIVQFLLEKGCDRSIVNKSRQTALDIAVFWGYKHIANLL 98
TALM A +GH E+ + LL+ G ++ S ++ L +A G+ +A LL
Sbjct: 407 TALMEACMDGHVEVARLLLDSGAQVNMPADSFESPLTLAACGGHVELAALL 457
Score = 33.1 bits (74), Expect = 0.55
Identities = 21/79 (26%), Positives = 37/79 (46%)
Query: 20 AAEGDIAKLTGILSHSPSLLNETSENGWTALMYAARNGHPEIVQFLLEKGCDRSIVNKSR 79
AA+ K +L H + ++ ++ G T L A+ GH ++VQ L++ G D + +
Sbjct: 1299 AADKGHYKFCELLIHRGAHIDVRNKKGNTPLWLASNGGHFDVVQLLVQAGADVDAADNRK 1358
Query: 80 QTALDIAVFWGYKHIANLL 98
T L A G+ + L
Sbjct: 1359 ITPLMSAFRKGHVKVVQYL 1377
Score = 32.3 bits (72), Expect = 0.93
Identities = 20/80 (25%), Positives = 36/80 (45%)
Query: 19 SAAEGDIAKLTGILSHSPSLLNETSENGWTALMYAARNGHPEIVQFLLEKGCDRSIVNKS 78
+A G + + ++S ++ T+ N T + A GH +V+ LL G D + K
Sbjct: 608 AARAGHLCTVQFLISKGANVNRATANNDHTVVSLACAGGHLAVVELLLAHGADPTHRLKD 667
Query: 79 RQTALDIAVFWGYKHIANLL 98
T L A G+ ++ + L
Sbjct: 668 GSTMLIEAAKGGHTNVVSYL 687
Score = 31.6 bits (70), Expect = 1.6
Identities = 23/81 (28%), Positives = 39/81 (48%), Gaps = 3/81 (3%)
Query: 18 CSAAEGDIAKLTGILSHSPSLLNETSENGWTALMYAARNGHPEIVQFLLEKGCDRSIVNK 77
C ++A+L L S + +N +++ + L AA GH E+ L+E+G + VN
Sbjct: 413 CMDGHVEVARL---LLDSGAQVNMPADSFESPLTLAACGGHVELAALLIERGANLEEVND 469
Query: 78 SRQTALDIAVFWGYKHIANLL 98
T L A G++ + LL
Sbjct: 470 EGYTPLMEAAREGHEEMVALL 490
Score = 31.6 bits (70), Expect = 1.6
Identities = 18/54 (33%), Positives = 26/54 (48%)
Query: 48 TALMYAARNGHPEIVQFLLEKGCDRSIVNKSRQTALDIAVFWGYKHIANLLATA 101
TAL AA GH + + L+ +G + NK T L +A G+ + LL A
Sbjct: 1294 TALTIAADKGHYKFCELLIHRGAHIDVRNKKGNTPLWLASNGGHFDVVQLLVQA 1347
Score = 30.8 bits (68), Expect = 2.7
Identities = 37/148 (25%), Positives = 60/148 (40%), Gaps = 15/148 (10%)
Query: 19 SAAEGDIAKLTGILSHSPSLLNETSENGWTALMYAARNGHPEIVQFLL------EKGCDR 72
+A EG + +L+ ++ +T E TAL A G E+ FL+ E GC
Sbjct: 478 AAREGHEEMVALLLAQGANINAQTEETQETALTLACCGGFSEVADFLIKAGADIELGCST 537
Query: 73 SIVNKSRQTALDIAVFWGYKHIANLLATAKGGKKPWFLTNEVEECENYFSKTLLDRKSEK 132
++ S++ L++ V + AN+ AT G LT E + LL ++
Sbjct: 538 PLMEASQEGHLEL-VKYLLASGANVHATTATGDTA--LTYACENGHTDVADVLLQAGADL 594
Query: 133 RNNSD------WLLAKESHPATVFILFS 154
+ S+ A+ H TV L S
Sbjct: 595 EHESEGGRTPLMKAARAGHLCTVQFLIS 622
Score = 30.0 bits (66), Expect = 4.6
Identities = 27/83 (32%), Positives = 38/83 (45%), Gaps = 6/83 (7%)
Query: 19 SAAEGDIAKLTGILSHSPSLLNETSENGWTALMYAARNGHPEIVQFLLEKGC---DRSIV 75
+ ++GD+ + +L S+ NE +E G + L A G+ E+ Q LL DR
Sbjct: 212 ACSDGDVNAVRKLLDEGRSV-NEHTEEGESLLCLACSAGYYELAQVLLAMHANVEDRG-- 268
Query: 76 NKSRQTALDIAVFWGYKHIANLL 98
NK T L A GY I LL
Sbjct: 269 NKGDITPLMAASSGGYLDIVKLL 291
Score = 29.6 bits (65), Expect = 6.0
Identities = 18/66 (27%), Positives = 33/66 (50%), Gaps = 1/66 (1%)
Query: 2 SSVKRSLKQEIVTQFHCSAAEGDIAKLTGILSHSPSLLNETSENGWTALMYAARNGHPEI 61
++V R+ T + A G +A + +L+H + + G T L+ AA+ GH +
Sbjct: 625 ANVNRATANNDHTVVSLACAGGHLAVVELLLAHGADPTHRLKD-GSTMLIEAAKGGHTNV 683
Query: 62 VQFLLE 67
V +LL+
Sbjct: 684 VSYLLD 689
Score = 29.3 bits (64), Expect = 7.9
Identities = 33/148 (22%), Positives = 56/148 (37%), Gaps = 14/148 (9%)
Query: 19 SAAEGDIAKLTGILSHSPSLLNETSENGWTALMYAARNGHPEIVQFLLEKGCDRSIVNKS 78
+A G + + +L + + N TAL A G E+V LL++ + K+
Sbjct: 1197 AAMNGHVPAVKLLLDMGSDINAQIETNRNTALTLACFQGRAEVVSLLLDRKANVEHRAKT 1256
Query: 79 RQTALDIAVFWGYKHIANLL--------ATAKGGKKPWFLTNEVEECENYFSKTLLDR-- 128
T L A GY + +L A + LT ++ F + L+ R
Sbjct: 1257 GLTPLMEAASGGYAEVGRVLLDKGADVNAPPVPSSRDTALTIAADKGHYKFCELLIHRGA 1316
Query: 129 ----KSEKRNNSDWLLAKESHPATVFIL 152
+++K N WL + H V +L
Sbjct: 1317 HIDVRNKKGNTPLWLASNGGHFDVVQLL 1344
>gi|37620163 ANKHD1-EIF4EBP3 protein [Homo sapiens]
Length = 2617
Score = 50.1 bits (118), Expect = 4e-06
Identities = 29/83 (34%), Positives = 47/83 (56%), Gaps = 1/83 (1%)
Query: 20 AAEGDIAKLTGILSHSPSLLNETSENGWTALMYAARNGHPEIVQFLLEKGCD-RSIVNKS 78
AA G +L +L + L E ++ G+T LM AAR GH E+V LL +G + + ++
Sbjct: 445 AACGGHVELAALLIERGANLEEVNDEGYTPLMEAAREGHEEMVALLLAQGANINAQTEET 504
Query: 79 RQTALDIAVFWGYKHIANLLATA 101
++TAL +A G+ +A+ L A
Sbjct: 505 QETALTLACCGGFSEVADFLIKA 527
Score = 43.9 bits (102), Expect = 3e-04
Identities = 30/86 (34%), Positives = 45/86 (52%), Gaps = 3/86 (3%)
Query: 20 AAEGDIAKLTGILSHSPSLLNET--SENGWTALMYAARNGHPEIVQFLLEKGCD-RSIVN 76
AA G + IL ++ + +N S+ G + LM AA NGH V+ LL+ G D + +
Sbjct: 1162 AASGGYVNIIKILLNAGAEINSRTGSKLGISPLMLAAMNGHVPAVKLLLDMGSDINAQIE 1221
Query: 77 KSRQTALDIAVFWGYKHIANLLATAK 102
+R TAL +A F G + +LL K
Sbjct: 1222 TNRNTALTLACFQGRAEVVSLLLDRK 1247
Score = 41.2 bits (95), Expect = 0.002
Identities = 24/83 (28%), Positives = 43/83 (51%), Gaps = 1/83 (1%)
Query: 20 AAEGDIAKLTGILSHSPSLLNETSENGWTALMYAARNGHPEIVQFLLEKGCD-RSIVNKS 78
A G + +L + + + + +ENG T LM AA GH E+ + LL+ G + N+
Sbjct: 312 ACAGGFVDIVKVLLNEGANIEDHNENGHTPLMEAASAGHVEVARVLLDHGAGINTHSNEF 371
Query: 79 RQTALDIAVFWGYKHIANLLATA 101
+++AL +A + G+ + L A
Sbjct: 372 KESALTLACYKGHLDMVRFLLEA 394
Score = 41.2 bits (95), Expect = 0.002
Identities = 25/80 (31%), Positives = 39/80 (48%)
Query: 19 SAAEGDIAKLTGILSHSPSLLNETSENGWTALMYAARNGHPEIVQFLLEKGCDRSIVNKS 78
+A+ G + +L H + ++E +AL A GH ++V+FLLE G D+
Sbjct: 345 AASAGHVEVARVLLDHGAGINTHSNEFKESALTLACYKGHLDMVRFLLEAGADQEHKTDE 404
Query: 79 RQTALDIAVFWGYKHIANLL 98
TAL A G+ +A LL
Sbjct: 405 MHTALMEACMDGHVEVARLL 424
Score = 40.4 bits (93), Expect = 0.003
Identities = 26/88 (29%), Positives = 45/88 (51%), Gaps = 2/88 (2%)
Query: 20 AAEGDIAKLTGILSHSPSLLNETSENGWTALMYAARNGHPEIVQFLLEKGCD-RSIVNKS 78
A G +L +L + + + G+T L+ AA GH +V+ LL+KG D + ++
Sbjct: 1062 ACAGGHEELVSVLIARDAKIEHRDKKGFTPLILAATAGHVGVVEILLDKGGDIEAQSERT 1121
Query: 79 RQTALDIAVFWGYKHIANLLATAKGGKK 106
+ T L +A G + + +LL A+G K
Sbjct: 1122 KDTPLSLACSGGRQEVVDLL-LARGANK 1148
Score = 39.7 bits (91), Expect = 0.006
Identities = 30/98 (30%), Positives = 44/98 (44%), Gaps = 11/98 (11%)
Query: 26 AKLTGILSHSPSLLNETSENGWTALMYAARNGHPEIVQFLLEKGCDRSI--VNKSRQTAL 83
A++ +L + + ++ G T LM AA G+ E+ + LL+KG D + V SR TAL
Sbjct: 1237 AEVVSLLLDRKANVEHRAKTGLTPLMEAASGGYAEVGRVLLDKGADVNAPPVPSSRDTAL 1296
Query: 84 DIAVFWGYKHIANLL---------ATAKGGKKPWFLTN 112
IA G+ LL KG W +N
Sbjct: 1297 TIAADKGHYKFCELLIHRGAHIDVRNKKGNTPLWLASN 1334
Score = 39.3 bits (90), Expect = 0.008
Identities = 31/94 (32%), Positives = 43/94 (45%), Gaps = 13/94 (13%)
Query: 17 HCSAAEGDIA----------KLTGILSHSPSLLNETSENGWTALMYAARNGHPEIVQFLL 66
H + A GD A + +L + + L SE G T LM AAR GH VQFL+
Sbjct: 562 HATTATGDTALTYACENGHTDVADVLLQAGADLEHESEGGRTPLMKAARAGHLCTVQFLI 621
Query: 67 EKGC--DRSIVNKSRQTALDIAVFWGYKHIANLL 98
KG +R+ N T + +A G+ + LL
Sbjct: 622 SKGANVNRATANND-HTVVSLACAGGHLAVVELL 654
Score = 36.6 bits (83), Expect = 0.049
Identities = 27/75 (36%), Positives = 38/75 (50%), Gaps = 3/75 (4%)
Query: 24 DIAKLTGILSHSPSLLNETSENGWTALMYAARNGHPEIVQFLLEKGCDRSIVNKSRQTAL 83
DI KL +L H + N S G TAL YA G +IV+ LL +G + N++ T L
Sbjct: 286 DIVKL--LLLHDADV-NSQSATGNTALTYACAGGFVDIVKVLLNEGANIEDHNENGHTPL 342
Query: 84 DIAVFWGYKHIANLL 98
A G+ +A +L
Sbjct: 343 MEAASAGHVEVARVL 357
Score = 35.4 bits (80), Expect = 0.11
Identities = 22/68 (32%), Positives = 35/68 (51%), Gaps = 8/68 (11%)
Query: 48 TALMYAARNGHPEIVQFLLEKGCDRSIVNKSRQTALDIAVFWGYKHIANLLATA------ 101
T LM A++ GH E+V++LL G + + TAL A G+ +A++L A
Sbjct: 537 TPLMEASQEGHLELVKYLLASGANVHATTATGDTALTYACENGHTDVADVLLQAGADLEH 596
Query: 102 --KGGKKP 107
+GG+ P
Sbjct: 597 ESEGGRTP 604
Score = 35.4 bits (80), Expect = 0.11
Identities = 21/65 (32%), Positives = 35/65 (53%), Gaps = 1/65 (1%)
Query: 19 SAAEGDIAKLTGILSHSPSLLNETSENGWTALMYAARNGHPEIVQFLLEKGCDRSIVNKS 78
++ EG + +L L S + ++ T+ G TAL YA NGH ++ LL+ G D ++
Sbjct: 542 ASQEGHL-ELVKYLLASGANVHATTATGDTALTYACENGHTDVADVLLQAGADLEHESEG 600
Query: 79 RQTAL 83
+T L
Sbjct: 601 GRTPL 605
Score = 35.4 bits (80), Expect = 0.11
Identities = 22/83 (26%), Positives = 36/83 (43%)
Query: 19 SAAEGDIAKLTGILSHSPSLLNETSENGWTALMYAARNGHPEIVQFLLEKGCDRSIVNKS 78
+A G + + +L + ++ T L A G E+V LL +G ++ N S
Sbjct: 1095 AATAGHVGVVEILLDKGGDIEAQSERTKDTPLSLACSGGRQEVVDLLLARGANKEHRNVS 1154
Query: 79 RQTALDIAVFWGYKHIANLLATA 101
T L +A GY +I +L A
Sbjct: 1155 DYTPLSLAASGGYVNIIKILLNA 1177
Score = 34.3 bits (77), Expect = 0.24
Identities = 18/51 (35%), Positives = 29/51 (56%)
Query: 48 TALMYAARNGHPEIVQFLLEKGCDRSIVNKSRQTALDIAVFWGYKHIANLL 98
TALM A +GH E+ + LL+ G ++ S ++ L +A G+ +A LL
Sbjct: 407 TALMEACMDGHVEVARLLLDSGAQVNMPADSFESPLTLAACGGHVELAALL 457
Score = 33.1 bits (74), Expect = 0.55
Identities = 21/79 (26%), Positives = 37/79 (46%)
Query: 20 AAEGDIAKLTGILSHSPSLLNETSENGWTALMYAARNGHPEIVQFLLEKGCDRSIVNKSR 79
AA+ K +L H + ++ ++ G T L A+ GH ++VQ L++ G D + +
Sbjct: 1299 AADKGHYKFCELLIHRGAHIDVRNKKGNTPLWLASNGGHFDVVQLLVQAGADVDAADNRK 1358
Query: 80 QTALDIAVFWGYKHIANLL 98
T L A G+ + L
Sbjct: 1359 ITPLMSAFRKGHVKVVQYL 1377
Score = 32.3 bits (72), Expect = 0.93
Identities = 20/80 (25%), Positives = 36/80 (45%)
Query: 19 SAAEGDIAKLTGILSHSPSLLNETSENGWTALMYAARNGHPEIVQFLLEKGCDRSIVNKS 78
+A G + + ++S ++ T+ N T + A GH +V+ LL G D + K
Sbjct: 608 AARAGHLCTVQFLISKGANVNRATANNDHTVVSLACAGGHLAVVELLLAHGADPTHRLKD 667
Query: 79 RQTALDIAVFWGYKHIANLL 98
T L A G+ ++ + L
Sbjct: 668 GSTMLIEAAKGGHTNVVSYL 687
Score = 31.6 bits (70), Expect = 1.6
Identities = 23/81 (28%), Positives = 39/81 (48%), Gaps = 3/81 (3%)
Query: 18 CSAAEGDIAKLTGILSHSPSLLNETSENGWTALMYAARNGHPEIVQFLLEKGCDRSIVNK 77
C ++A+L L S + +N +++ + L AA GH E+ L+E+G + VN
Sbjct: 413 CMDGHVEVARL---LLDSGAQVNMPADSFESPLTLAACGGHVELAALLIERGANLEEVND 469
Query: 78 SRQTALDIAVFWGYKHIANLL 98
T L A G++ + LL
Sbjct: 470 EGYTPLMEAAREGHEEMVALL 490
Score = 31.6 bits (70), Expect = 1.6
Identities = 18/54 (33%), Positives = 26/54 (48%)
Query: 48 TALMYAARNGHPEIVQFLLEKGCDRSIVNKSRQTALDIAVFWGYKHIANLLATA 101
TAL AA GH + + L+ +G + NK T L +A G+ + LL A
Sbjct: 1294 TALTIAADKGHYKFCELLIHRGAHIDVRNKKGNTPLWLASNGGHFDVVQLLVQA 1347
Score = 30.8 bits (68), Expect = 2.7
Identities = 37/148 (25%), Positives = 60/148 (40%), Gaps = 15/148 (10%)
Query: 19 SAAEGDIAKLTGILSHSPSLLNETSENGWTALMYAARNGHPEIVQFLL------EKGCDR 72
+A EG + +L+ ++ +T E TAL A G E+ FL+ E GC
Sbjct: 478 AAREGHEEMVALLLAQGANINAQTEETQETALTLACCGGFSEVADFLIKAGADIELGCST 537
Query: 73 SIVNKSRQTALDIAVFWGYKHIANLLATAKGGKKPWFLTNEVEECENYFSKTLLDRKSEK 132
++ S++ L++ V + AN+ AT G LT E + LL ++
Sbjct: 538 PLMEASQEGHLEL-VKYLLASGANVHATTATGDTA--LTYACENGHTDVADVLLQAGADL 594
Query: 133 RNNSD------WLLAKESHPATVFILFS 154
+ S+ A+ H TV L S
Sbjct: 595 EHESEGGRTPLMKAARAGHLCTVQFLIS 622
Score = 30.0 bits (66), Expect = 4.6
Identities = 27/83 (32%), Positives = 38/83 (45%), Gaps = 6/83 (7%)
Query: 19 SAAEGDIAKLTGILSHSPSLLNETSENGWTALMYAARNGHPEIVQFLLEKGC---DRSIV 75
+ ++GD+ + +L S+ NE +E G + L A G+ E+ Q LL DR
Sbjct: 212 ACSDGDVNAVRKLLDEGRSV-NEHTEEGESLLCLACSAGYYELAQVLLAMHANVEDRG-- 268
Query: 76 NKSRQTALDIAVFWGYKHIANLL 98
NK T L A GY I LL
Sbjct: 269 NKGDITPLMAASSGGYLDIVKLL 291
Score = 29.6 bits (65), Expect = 6.0
Identities = 18/66 (27%), Positives = 33/66 (50%), Gaps = 1/66 (1%)
Query: 2 SSVKRSLKQEIVTQFHCSAAEGDIAKLTGILSHSPSLLNETSENGWTALMYAARNGHPEI 61
++V R+ T + A G +A + +L+H + + G T L+ AA+ GH +
Sbjct: 625 ANVNRATANNDHTVVSLACAGGHLAVVELLLAHGADPTHRLKD-GSTMLIEAAKGGHTNV 683
Query: 62 VQFLLE 67
V +LL+
Sbjct: 684 VSYLLD 689
Score = 29.3 bits (64), Expect = 7.9
Identities = 33/148 (22%), Positives = 56/148 (37%), Gaps = 14/148 (9%)
Query: 19 SAAEGDIAKLTGILSHSPSLLNETSENGWTALMYAARNGHPEIVQFLLEKGCDRSIVNKS 78
+A G + + +L + + N TAL A G E+V LL++ + K+
Sbjct: 1197 AAMNGHVPAVKLLLDMGSDINAQIETNRNTALTLACFQGRAEVVSLLLDRKANVEHRAKT 1256
Query: 79 RQTALDIAVFWGYKHIANLL--------ATAKGGKKPWFLTNEVEECENYFSKTLLDR-- 128
T L A GY + +L A + LT ++ F + L+ R
Sbjct: 1257 GLTPLMEAASGGYAEVGRVLLDKGADVNAPPVPSSRDTALTIAADKGHYKFCELLIHRGA 1316
Query: 129 ----KSEKRNNSDWLLAKESHPATVFIL 152
+++K N WL + H V +L
Sbjct: 1317 HIDVRNKKGNTPLWLASNGGHFDVVQLL 1344
>gi|21264330 mindbomb homolog 2 [Homo sapiens]
Length = 1013
Score = 50.1 bits (118), Expect = 4e-06
Identities = 29/89 (32%), Positives = 49/89 (55%), Gaps = 1/89 (1%)
Query: 14 TQFHCSAAEGDIAKLTGILSHSPSLLNETSENGWTALMYAARNGHPEIVQFLLEKG-CDR 72
T H ++ +G + IL+ + L++ E+G+TAL AA N H E+ Q L+ +G CD
Sbjct: 660 TLLHHASLKGHALAVRKILARARQLVDAKKEDGFTALHLAALNNHREVAQILIREGRCDV 719
Query: 73 SIVNKSRQTALDIAVFWGYKHIANLLATA 101
++ N+ Q+ L +AV + + LL A
Sbjct: 720 NVRNRKLQSPLHLAVQQAHVGLVPLLVDA 748
Score = 42.4 bits (98), Expect = 9e-04
Identities = 21/55 (38%), Positives = 29/55 (52%)
Query: 44 ENGWTALMYAARNGHPEIVQFLLEKGCDRSIVNKSRQTALDIAVFWGYKHIANLL 98
+ G TAL YAA PE + LL GC +N ++ TAL +AV G+ + L
Sbjct: 554 DEGNTALHYAALGNQPEATRVLLSAGCRADAINSTQSTALHVAVQRGFLEVVRAL 608
Score = 32.7 bits (73), Expect = 0.71
Identities = 21/71 (29%), Positives = 35/71 (49%)
Query: 20 AAEGDIAKLTGILSHSPSLLNETSENGWTALMYAARNGHPEIVQFLLEKGCDRSIVNKSR 79
AA G+ + T +L + + + TAL A + G E+V+ L E+GCD ++ +
Sbjct: 563 AALGNQPEATRVLLSAGCRADAINSTQSTALHVAVQRGFLEVVRALCERGCDVNLPDAHS 622
Query: 80 QTALDIAVFWG 90
T L A+ G
Sbjct: 623 DTPLHSAISAG 633
Score = 31.2 bits (69), Expect = 2.1
Identities = 23/90 (25%), Positives = 47/90 (52%), Gaps = 7/90 (7%)
Query: 14 TQFHCSAAEGDIAK-LTGILSHSPSL-LNETSENGWTALMYAARNGHPEIVQFLLEKGCD 71
T H + + G A + +L+ P++ + T+ G+T L +A+ GH V+ +L +
Sbjct: 624 TPLHSAISAGTGASGIVEVLTEVPNIDVTATNSQGFTLLHHASLKGHALAVRKILARA-- 681
Query: 72 RSIVNKSRQ---TALDIAVFWGYKHIANLL 98
R +V+ ++ TAL +A ++ +A +L
Sbjct: 682 RQLVDAKKEDGFTALHLAALNNHREVAQIL 711
Score = 30.8 bits (68), Expect = 2.7
Identities = 22/81 (27%), Positives = 35/81 (43%), Gaps = 1/81 (1%)
Query: 21 AEGDIAKLTGILSHSPSLLNETSENGWTALMYAARNGHPEIVQFLLEKGCDRSIVNKSRQ 80
A G+ A+ +L P + +T G TAL AA G E+++ LL+ + +
Sbjct: 499 ALGNAARALDLLRRRPEQV-DTKNQGRTALQVAAYLGQVELIRLLLQARAGVDLPDDEGN 557
Query: 81 TALDIAVFWGYKHIANLLATA 101
TAL A +L +A
Sbjct: 558 TALHYAALGNQPEATRVLLSA 578
>gi|154354990 ankyrin repeat domain 26 [Homo sapiens]
Length = 1710
Score = 50.1 bits (118), Expect = 4e-06
Identities = 26/73 (35%), Positives = 43/73 (58%)
Query: 15 QFHCSAAEGDIAKLTGILSHSPSLLNETSENGWTALMYAARNGHPEIVQFLLEKGCDRSI 74
+ H +A+ G++AK+ IL + LN+ + TAL A NGHPE+V L+++ C ++
Sbjct: 49 KIHKAASAGNVAKVQQILLLRKNGLNDRDKMNRTALHLACANGHPEVVTLLVDRKCQLNV 108
Query: 75 VNKSRQTALDIAV 87
+ +TAL AV
Sbjct: 109 CDNENRTALMKAV 121
>gi|116325987 ankyrin repeat domain 42 [Homo sapiens]
Length = 389
Score = 50.1 bits (118), Expect = 4e-06
Identities = 26/82 (31%), Positives = 45/82 (54%)
Query: 17 HCSAAEGDIAKLTGILSHSPSLLNETSENGWTALMYAARNGHPEIVQFLLEKGCDRSIVN 76
H +A +GD+ L ++ +NE ++NG T + AA GH E +Q+L++ G D +I N
Sbjct: 241 HVAAFKGDLGMLKKLVEDGVININERADNGSTPMHKAAGQGHIECLQWLIKMGADSNITN 300
Query: 77 KSRQTALDIAVFWGYKHIANLL 98
K+ + D+A + + LL
Sbjct: 301 KAGERPSDVAKRFAHLAAVKLL 322
Score = 36.2 bits (82), Expect = 0.064
Identities = 22/77 (28%), Positives = 36/77 (46%), Gaps = 1/77 (1%)
Query: 14 TQFHCSAAEGDIAKLTGILSHSPSLLNETSENGWTALMYAARNGHPEIVQFLLEKGCDRS 73
T H +A G A + ++ + +L + + G T L AA +GH +Q +L G D S
Sbjct: 67 TASHIAAIRGQDACVQALIMNGANLTAQ-DDRGCTPLHLAATHGHSFTLQIMLRSGVDPS 125
Query: 74 IVNKSRQTALDIAVFWG 90
+ +K + A F G
Sbjct: 126 VTDKREWRPVHYAAFHG 142
Score = 29.6 bits (65), Expect = 6.0
Identities = 23/89 (25%), Positives = 38/89 (42%), Gaps = 5/89 (5%)
Query: 14 TQFHCSAAEGDIAKLTGILSHS--PSLLNETSENGWTALMYAARNGHPEIVQFLLEKGCD 71
T H +A G L +L PS+ T + W + YAA +G +Q L++ GC
Sbjct: 100 TPLHLAATHGHSFTLQIMLRSGVDPSV---TDKREWRPVHYAAFHGRLGCLQLLVKWGCS 156
Query: 72 RSIVNKSRQTALDIAVFWGYKHIANLLAT 100
V+ + + +A G+ H L +
Sbjct: 157 IEDVDYNGNLPVHLAAMEGHLHCFKFLVS 185
>gi|90186267 ankyrin repeat domain 55 isoform 1 [Homo sapiens]
Length = 614
Score = 49.7 bits (117), Expect = 6e-06
Identities = 31/89 (34%), Positives = 49/89 (55%), Gaps = 1/89 (1%)
Query: 17 HCSAAEGDIAKLTGILSHSP-SLLNETSENGWTALMYAARNGHPEIVQFLLEKGCDRSIV 75
H + AE D+ LT +L S S +N G T L +AA + P+ Q LL+KG D ++V
Sbjct: 132 HAATAEPDMRLLTVLLQQSNISEINHQDNEGMTPLHWAAFHNQPQHTQMLLKKGADPTLV 191
Query: 76 NKSRQTALDIAVFWGYKHIANLLATAKGG 104
+K +TAL AV G + + +++ + G
Sbjct: 192 DKDFKTALHWAVQSGNRILCSIILSHHQG 220
Score = 44.3 bits (103), Expect = 2e-04
Identities = 22/79 (27%), Positives = 43/79 (54%)
Query: 13 VTQFHCSAAEGDIAKLTGILSHSPSLLNETSENGWTALMYAARNGHPEIVQFLLEKGCDR 72
+T + +A+ GD+ LT ++ PS+L G T LM+A + V+ LL+ G +
Sbjct: 28 LTMVYQAASNGDVNALTAVIREDPSILECCDSEGCTPLMHAVSGRQADTVKLLLKMGANI 87
Query: 73 SIVNKSRQTALDIAVFWGY 91
++ + +T+L +A + G+
Sbjct: 88 NMQDAYGRTSLCLATYLGW 106
Score = 32.3 bits (72), Expect = 0.93
Identities = 19/52 (36%), Positives = 28/52 (53%)
Query: 48 TALMYAARNGHPEIVQFLLEKGCDRSIVNKSRQTALDIAVFWGYKHIANLLA 99
T L +AA G E VQ LLE G D ++ + + T L A++ G+ LL+
Sbjct: 267 TPLHWAAAAGKAECVQSLLELGMDSNLRDINESTPLAYALYCGHTACVKLLS 318
>gi|156142199 euchromatic histone-lysine N-methyltransferase 2
isoform b [Homo sapiens]
Length = 1176
Score = 49.3 bits (116), Expect = 7e-06
Identities = 27/96 (28%), Positives = 50/96 (52%)
Query: 7 SLKQEIVTQFHCSAAEGDIAKLTGILSHSPSLLNETSENGWTALMYAARNGHPEIVQFLL 66
S +++ T H +A G++ ++ +LS +N GWT +++AA + H E+++ LL
Sbjct: 712 SKEEDGSTCLHHAAKIGNLEMVSLLLSTGQVDVNAQDSGGWTPIIWAAEHKHIEVIRMLL 771
Query: 67 EKGCDRSIVNKSRQTALDIAVFWGYKHIANLLATAK 102
+G D ++ + L A F G IA +L A+
Sbjct: 772 TRGADVTLTDNEENICLHWASFTGSAAIAEVLLNAR 807
Score = 29.3 bits (64), Expect = 7.9
Identities = 17/60 (28%), Positives = 30/60 (50%)
Query: 26 AKLTGILSHSPSLLNETSENGWTALMYAARNGHPEIVQFLLEKGCDRSIVNKSRQTALDI 85
A + +L ++ L+ + +G T L AAR + + V L +G + + NK TA D+
Sbjct: 797 AAIAEVLLNARCDLHAVNYHGDTPLHIAARESYHDCVLLFLSRGANPELRNKEGDTAWDL 856
>gi|156142197 euchromatic histone-lysine N-methyltransferase 2
isoform a [Homo sapiens]
Length = 1210
Score = 49.3 bits (116), Expect = 7e-06
Identities = 27/96 (28%), Positives = 50/96 (52%)
Query: 7 SLKQEIVTQFHCSAAEGDIAKLTGILSHSPSLLNETSENGWTALMYAARNGHPEIVQFLL 66
S +++ T H +A G++ ++ +LS +N GWT +++AA + H E+++ LL
Sbjct: 746 SKEEDGSTCLHHAAKIGNLEMVSLLLSTGQVDVNAQDSGGWTPIIWAAEHKHIEVIRMLL 805
Query: 67 EKGCDRSIVNKSRQTALDIAVFWGYKHIANLLATAK 102
+G D ++ + L A F G IA +L A+
Sbjct: 806 TRGADVTLTDNEENICLHWASFTGSAAIAEVLLNAR 841
Score = 29.3 bits (64), Expect = 7.9
Identities = 17/60 (28%), Positives = 30/60 (50%)
Query: 26 AKLTGILSHSPSLLNETSENGWTALMYAARNGHPEIVQFLLEKGCDRSIVNKSRQTALDI 85
A + +L ++ L+ + +G T L AAR + + V L +G + + NK TA D+
Sbjct: 831 AAIAEVLLNARCDLHAVNYHGDTPLHIAARESYHDCVLLFLSRGANPELRNKEGDTAWDL 890
>gi|157743284 ankyrin repeat domain 52 [Homo sapiens]
Length = 1076
Score = 49.3 bits (116), Expect = 7e-06
Identities = 29/86 (33%), Positives = 49/86 (56%), Gaps = 2/86 (2%)
Query: 14 TQFHCSAAEGDIAKLTGILSHSPSLLNETSENGWTALMYAARNGHPEIVQFLLEKG-CDR 72
T H +A +++ L +L H + N T G TALM AA NG V+FLL +G D
Sbjct: 860 TPLHAAAFADNVSGLRMLLQHQAEV-NATDHTGRTALMTAAENGQTAAVEFLLYRGKADL 918
Query: 73 SIVNKSRQTALDIAVFWGYKHIANLL 98
+++++++ TAL +A G++ A ++
Sbjct: 919 TVLDENKNTALHLACSKGHEKCALMI 944
Score = 43.1 bits (100), Expect = 5e-04
Identities = 28/85 (32%), Positives = 40/85 (47%), Gaps = 1/85 (1%)
Query: 14 TQFHCSAAEGDIAKLTGILSHSPSLLNETSENGWTALMYAARNGHPEIVQFLLEKGCDRS 73
T H +AA K L+ S LN +G +AL +A +GH E V LL KG +
Sbjct: 109 TPLHVAAANR-ATKCAEALAPLLSSLNVADRSGRSALHHAVHSGHLETVNLLLNKGASLN 167
Query: 74 IVNKSRQTALDIAVFWGYKHIANLL 98
+ +K + L A F G+ + LL
Sbjct: 168 VCDKKERQPLHWAAFLGHLEVLKLL 192
Score = 34.3 bits (77), Expect = 0.24
Identities = 23/72 (31%), Positives = 31/72 (43%), Gaps = 2/72 (2%)
Query: 14 TQFHCSAAEGDIAKLTGILSHSP--SLLNETSENGWTALMYAARNGHPEIVQFLLEKGCD 71
T H +AA G L ++ + + G T LM A NGH + V LLEKG
Sbjct: 654 TPLHAAAASGHTDSLHLLIDSGERADITDVMDAYGQTPLMLAIMNGHVDCVHLLLEKGST 713
Query: 72 RSIVNKSRQTAL 83
+ +TAL
Sbjct: 714 ADAADLRGRTAL 725
Score = 32.0 bits (71), Expect = 1.2
Identities = 20/56 (35%), Positives = 28/56 (50%)
Query: 46 GWTALMYAARNGHPEIVQFLLEKGCDRSIVNKSRQTALDIAVFWGYKHIANLLATA 101
G+ L AA +G E+V++LL G + N TAL IA + G +A L A
Sbjct: 206 GYGLLHTAAASGQIEVVKYLLRMGAEIDEPNAFGNTALHIACYLGQDAVAIELVNA 261
Score = 32.0 bits (71), Expect = 1.2
Identities = 20/72 (27%), Positives = 38/72 (52%), Gaps = 5/72 (6%)
Query: 31 ILSHSPSLLNETSENGWTALMYAARNGHPEIVQFLLEKGCDRS----IVNKSRQTALDIA 86
+ +H S L + + WT L AA +GH + + L++ G +R+ +++ QT L +A
Sbjct: 637 LTAHGASALIKERKRKWTPLHAAAASGHTDSLHLLIDSG-ERADITDVMDAYGQTPLMLA 695
Query: 87 VFWGYKHIANLL 98
+ G+ +LL
Sbjct: 696 IMNGHVDCVHLL 707
Score = 29.3 bits (64), Expect = 7.9
Identities = 22/85 (25%), Positives = 38/85 (44%), Gaps = 1/85 (1%)
Query: 17 HCSAAEGDIAKLTGILSHSPSLLNETSENGWTALMYAARNGHPEIVQFLLEKGCDRSIVN 76
H +A G + + IL + S ++ + G T L AAR GH ++ L+ G D +
Sbjct: 311 HMAAIHGRFTR-SQILIQNGSEIDCADKFGNTPLHVAARYGHELLISTLMTNGADTARRG 369
Query: 77 KSRQTALDIAVFWGYKHIANLLATA 101
L +AV +G+ L ++
Sbjct: 370 IHDMFPLHLAVLFGFSDCCRKLLSS 394
>gi|38683807 ankyrin repeat domain protein 17 isoform a [Homo
sapiens]
Length = 2603
Score = 49.3 bits (116), Expect = 7e-06
Identities = 29/83 (34%), Positives = 47/83 (56%), Gaps = 1/83 (1%)
Query: 20 AAEGDIAKLTGILSHSPSLLNETSENGWTALMYAARNGHPEIVQFLLEKGCD-RSIVNKS 78
AA G +L +L + L E ++ G+T LM AAR GH E+V LL +G + + ++
Sbjct: 474 AACGGHVELAALLIERGASLEEVNDEGYTPLMEAAREGHEEMVALLLGQGANINAQTEET 533
Query: 79 RQTALDIAVFWGYKHIANLLATA 101
++TAL +A G+ +A+ L A
Sbjct: 534 QETALTLACCGGFLEVADFLIKA 556
Score = 44.3 bits (103), Expect = 2e-04
Identities = 30/86 (34%), Positives = 45/86 (52%), Gaps = 3/86 (3%)
Query: 20 AAEGDIAKLTGILSHSPSLLNET--SENGWTALMYAARNGHPEIVQFLLEKGCD-RSIVN 76
AA G + IL ++ + +N S+ G + LM AA NGH V+ LL+ G D + +
Sbjct: 1190 AASGGYVNIIKILLNAGAEINSRTGSKLGISPLMLAAMNGHTAAVKLLLDMGSDINAQIE 1249
Query: 77 KSRQTALDIAVFWGYKHIANLLATAK 102
+R TAL +A F G + +LL K
Sbjct: 1250 TNRNTALTLACFQGRTEVVSLLLDRK 1275
Score = 43.1 bits (100), Expect = 5e-04
Identities = 26/87 (29%), Positives = 45/87 (51%), Gaps = 4/87 (4%)
Query: 16 FHCSAAEGDIAKLTGILSHSPSLLNETSENGWTALMYAARNGHPEIVQFLLEKGCD-RSI 74
+ C+ D+ K +L S + + + +ENG T LM A GH E+ + LLE G +
Sbjct: 340 YACAGGYVDVVK---VLLESGASIEDHNENGHTPLMEAGSAGHVEVARLLLENGAGINTH 396
Query: 75 VNKSRQTALDIAVFWGYKHIANLLATA 101
N+ +++AL +A + G+ + L A
Sbjct: 397 SNEFKESALTLACYKGHLEMVRFLLEA 423
Score = 41.6 bits (96), Expect = 0.002
Identities = 27/80 (33%), Positives = 40/80 (50%)
Query: 19 SAAEGDIAKLTGILSHSPSLLNETSENGWTALMYAARNGHPEIVQFLLEKGCDRSIVNKS 78
+AA G K+ +L + +N S G TAL YA G+ ++V+ LLE G N++
Sbjct: 307 AAANGGHVKIVKLLLAHKADVNAQSSTGNTALTYACAGGYVDVVKVLLESGASIEDHNEN 366
Query: 79 RQTALDIAVFWGYKHIANLL 98
T L A G+ +A LL
Sbjct: 367 GHTPLMEAGSAGHVEVARLL 386
Score = 40.8 bits (94), Expect = 0.003
Identities = 32/94 (34%), Positives = 43/94 (45%), Gaps = 13/94 (13%)
Query: 17 HCSAAEGDIA----------KLTGILSHSPSLLNETSENGWTALMYAARNGHPEIVQFLL 66
H + A GD A + +L + + L SE G T LM AAR GH VQFL+
Sbjct: 591 HATTATGDTALTYACENGHTDVADVLLQAGADLEHESEGGRTPLMKAARAGHVCTVQFLI 650
Query: 67 EKGC--DRSIVNKSRQTALDIAVFWGYKHIANLL 98
KG +R+ N T L +A G+ + LL
Sbjct: 651 SKGANVNRTTANND-HTVLSLACAGGHLAVVELL 683
Score = 40.4 bits (93), Expect = 0.003
Identities = 27/80 (33%), Positives = 41/80 (51%), Gaps = 2/80 (2%)
Query: 19 SAAEGDIAKLTGILSHSPSLLNETSENGWTALMYAARNGHPEIVQFLLEKGCDRSIVNKS 78
SA ++A+L +L + + ++E +AL A GH E+V+FLLE G D+
Sbjct: 376 SAGHVEVARL--LLENGAGINTHSNEFKESALTLACYKGHLEMVRFLLEAGADQEHKTDE 433
Query: 79 RQTALDIAVFWGYKHIANLL 98
TAL A G+ +A LL
Sbjct: 434 MHTALMEACMDGHVEVARLL 453
Score = 38.5 bits (88), Expect = 0.013
Identities = 35/128 (27%), Positives = 54/128 (42%), Gaps = 23/128 (17%)
Query: 27 KLTGILSHSPSLLNETSENGWTALMYAARNGHPEIVQFLLEKGCDRSI--VNKSRQTALD 84
++ +L + + ++ G T LM AA G+ E+ + LL+KG D + V SR TAL
Sbjct: 1266 EVVSLLLDRKANVEHRAKTGLTPLMEAASGGYAEVGRVLLDKGADVNAPPVPSSRDTALT 1325
Query: 85 IAVFWGYKHIANLLATAKGGKKPWFLTNEVEECENYFSKTLLDRKSEKRNNSDWLLAKES 144
IA G+ LL +G +D +++K N WL A
Sbjct: 1326 IAADKGHYKFCELL-IGRGAH--------------------IDVRNKKGNTPLWLAANGG 1364
Query: 145 HPATVFIL 152
H V +L
Sbjct: 1365 HLDVVQLL 1372
Score = 37.4 bits (85), Expect = 0.029
Identities = 25/88 (28%), Positives = 42/88 (47%), Gaps = 2/88 (2%)
Query: 20 AAEGDIAKLTGILSHSPSLLNETSENGWTALMYAARNGHPEIVQFLLEKGCD-RSIVNKS 78
A G +L L + + + G+T L+ AA GH +V+ LL+ G D + ++
Sbjct: 1090 ACAGGHEELVQTLLERGASIEHRDKKGFTPLILAATAGHVGVVEILLDNGADIEAQSERT 1149
Query: 79 RQTALDIAVFWGYKHIANLLATAKGGKK 106
+ T L +A G + + LL A+G K
Sbjct: 1150 KDTPLSLACSGGRQEVVELL-LARGANK 1176
Score = 37.4 bits (85), Expect = 0.029
Identities = 22/83 (26%), Positives = 38/83 (45%)
Query: 19 SAAEGDIAKLTGILSHSPSLLNETSENGWTALMYAARNGHPEIVQFLLEKGCDRSIVNKS 78
+A G + + +L + + ++ T L A G E+V+ LL +G ++ N S
Sbjct: 1123 AATAGHVGVVEILLDNGADIEAQSERTKDTPLSLACSGGRQEVVELLLARGANKEHRNVS 1182
Query: 79 RQTALDIAVFWGYKHIANLLATA 101
T L +A GY +I +L A
Sbjct: 1183 DYTPLSLAASGGYVNIIKILLNA 1205
Score = 36.2 bits (82), Expect = 0.064
Identities = 23/68 (33%), Positives = 35/68 (51%), Gaps = 8/68 (11%)
Query: 48 TALMYAARNGHPEIVQFLLEKGCDRSIVNKSRQTALDIAVFWGYKHIANLLATA------ 101
T LM AA+ GH E+V++LL G + + TAL A G+ +A++L A
Sbjct: 566 TPLMEAAQEGHLELVKYLLAAGANVHATTATGDTALTYACENGHTDVADVLLQAGADLEH 625
Query: 102 --KGGKKP 107
+GG+ P
Sbjct: 626 ESEGGRTP 633
Score = 35.4 bits (80), Expect = 0.11
Identities = 20/65 (30%), Positives = 35/65 (53%), Gaps = 1/65 (1%)
Query: 19 SAAEGDIAKLTGILSHSPSLLNETSENGWTALMYAARNGHPEIVQFLLEKGCDRSIVNKS 78
+A EG + + +L+ ++ + T+ G TAL YA NGH ++ LL+ G D ++
Sbjct: 571 AAQEGHLELVKYLLAAGANV-HATTATGDTALTYACENGHTDVADVLLQAGADLEHESEG 629
Query: 79 RQTAL 83
+T L
Sbjct: 630 GRTPL 634
Score = 35.4 bits (80), Expect = 0.11
Identities = 21/58 (36%), Positives = 29/58 (50%)
Query: 41 ETSENGWTALMYAARNGHPEIVQFLLEKGCDRSIVNKSRQTALDIAVFWGYKHIANLL 98
+T N TAL A GH E+VQ LLE+G +K T L +A G+ + +L
Sbjct: 1078 QTESNHDTALTLACAGGHEELVQTLLERGASIEHRDKKGFTPLILAATAGHVGVVEIL 1135
Score = 35.0 bits (79), Expect = 0.14
Identities = 24/81 (29%), Positives = 41/81 (50%), Gaps = 2/81 (2%)
Query: 18 CSAAEGDIAKLTGILSHSPSLLNETSENGWTALMYAARNGHPEIVQFLLEKGCDRSIVNK 77
CSA ++A++ +L+ ++ + + T LM AA GH +IV+ LL D + +
Sbjct: 275 CSAGYYELAQV--LLAMHANVEDRGIKGDITPLMAAANGGHVKIVKLLLAHKADVNAQSS 332
Query: 78 SRQTALDIAVFWGYKHIANLL 98
+ TAL A GY + +L
Sbjct: 333 TGNTALTYACAGGYVDVVKVL 353
Score = 34.3 bits (77), Expect = 0.24
Identities = 18/51 (35%), Positives = 29/51 (56%)
Query: 48 TALMYAARNGHPEIVQFLLEKGCDRSIVNKSRQTALDIAVFWGYKHIANLL 98
TALM A +GH E+ + LL+ G ++ S ++ L +A G+ +A LL
Sbjct: 436 TALMEACMDGHVEVARLLLDSGAQVNMPADSFESPLTLAACGGHVELAALL 486
Score = 32.0 bits (71), Expect = 1.2
Identities = 18/54 (33%), Positives = 26/54 (48%)
Query: 48 TALMYAARNGHPEIVQFLLEKGCDRSIVNKSRQTALDIAVFWGYKHIANLLATA 101
TAL AA GH + + L+ +G + NK T L +A G+ + LL A
Sbjct: 1322 TALTIAADKGHYKFCELLIGRGAHIDVRNKKGNTPLWLAANGGHLDVVQLLVQA 1375
Score = 31.6 bits (70), Expect = 1.6
Identities = 20/76 (26%), Positives = 33/76 (43%)
Query: 19 SAAEGDIAKLTGILSHSPSLLNETSENGWTALMYAARNGHPEIVQFLLEKGCDRSIVNKS 78
+A G + + ++S ++ T+ N T L A GH +V+ LL G D + K
Sbjct: 637 AARAGHVCTVQFLISKGANVNRTTANNDHTVLSLACAGGHLAVVELLLAHGADPTHRLKD 696
Query: 79 RQTALDIAVFWGYKHI 94
T L A G+ +
Sbjct: 697 GSTMLIEAAKGGHTSV 712
Score = 31.2 bits (69), Expect = 2.1
Identities = 23/81 (28%), Positives = 38/81 (46%), Gaps = 3/81 (3%)
Query: 18 CSAAEGDIAKLTGILSHSPSLLNETSENGWTALMYAARNGHPEIVQFLLEKGCDRSIVNK 77
C ++A+L L S + +N +++ + L AA GH E+ L+E+G VN
Sbjct: 442 CMDGHVEVARL---LLDSGAQVNMPADSFESPLTLAACGGHVELAALLIERGASLEEVND 498
Query: 78 SRQTALDIAVFWGYKHIANLL 98
T L A G++ + LL
Sbjct: 499 EGYTPLMEAAREGHEEMVALL 519
Score = 31.2 bits (69), Expect = 2.1
Identities = 21/79 (26%), Positives = 36/79 (45%)
Query: 20 AAEGDIAKLTGILSHSPSLLNETSENGWTALMYAARNGHPEIVQFLLEKGCDRSIVNKSR 79
AA+ K +L + ++ ++ G T L AA GH ++VQ L++ G D + +
Sbjct: 1327 AADKGHYKFCELLIGRGAHIDVRNKKGNTPLWLAANGGHLDVVQLLVQAGADVDAADNRK 1386
Query: 80 QTALDIAVFWGYKHIANLL 98
T L A G+ + L
Sbjct: 1387 ITPLMAAFRKGHVKVVRYL 1405
>gi|38683816 ankyrin repeat domain protein 17 isoform b [Homo
sapiens]
Length = 2352
Score = 49.3 bits (116), Expect = 7e-06
Identities = 29/83 (34%), Positives = 47/83 (56%), Gaps = 1/83 (1%)
Query: 20 AAEGDIAKLTGILSHSPSLLNETSENGWTALMYAARNGHPEIVQFLLEKGCD-RSIVNKS 78
AA G +L +L + L E ++ G+T LM AAR GH E+V LL +G + + ++
Sbjct: 474 AACGGHVELAALLIERGASLEEVNDEGYTPLMEAAREGHEEMVALLLGQGANINAQTEET 533
Query: 79 RQTALDIAVFWGYKHIANLLATA 101
++TAL +A G+ +A+ L A
Sbjct: 534 QETALTLACCGGFLEVADFLIKA 556
Score = 44.3 bits (103), Expect = 2e-04
Identities = 30/86 (34%), Positives = 45/86 (52%), Gaps = 3/86 (3%)
Query: 20 AAEGDIAKLTGILSHSPSLLNET--SENGWTALMYAARNGHPEIVQFLLEKGCD-RSIVN 76
AA G + IL ++ + +N S+ G + LM AA NGH V+ LL+ G D + +
Sbjct: 939 AASGGYVNIIKILLNAGAEINSRTGSKLGISPLMLAAMNGHTAAVKLLLDMGSDINAQIE 998
Query: 77 KSRQTALDIAVFWGYKHIANLLATAK 102
+R TAL +A F G + +LL K
Sbjct: 999 TNRNTALTLACFQGRTEVVSLLLDRK 1024
Score = 43.1 bits (100), Expect = 5e-04
Identities = 26/87 (29%), Positives = 45/87 (51%), Gaps = 4/87 (4%)
Query: 16 FHCSAAEGDIAKLTGILSHSPSLLNETSENGWTALMYAARNGHPEIVQFLLEKGCD-RSI 74
+ C+ D+ K +L S + + + +ENG T LM A GH E+ + LLE G +
Sbjct: 340 YACAGGYVDVVK---VLLESGASIEDHNENGHTPLMEAGSAGHVEVARLLLENGAGINTH 396
Query: 75 VNKSRQTALDIAVFWGYKHIANLLATA 101
N+ +++AL +A + G+ + L A
Sbjct: 397 SNEFKESALTLACYKGHLEMVRFLLEA 423
Score = 41.6 bits (96), Expect = 0.002
Identities = 27/80 (33%), Positives = 40/80 (50%)
Query: 19 SAAEGDIAKLTGILSHSPSLLNETSENGWTALMYAARNGHPEIVQFLLEKGCDRSIVNKS 78
+AA G K+ +L + +N S G TAL YA G+ ++V+ LLE G N++
Sbjct: 307 AAANGGHVKIVKLLLAHKADVNAQSSTGNTALTYACAGGYVDVVKVLLESGASIEDHNEN 366
Query: 79 RQTALDIAVFWGYKHIANLL 98
T L A G+ +A LL
Sbjct: 367 GHTPLMEAGSAGHVEVARLL 386
Score = 40.8 bits (94), Expect = 0.003
Identities = 32/94 (34%), Positives = 43/94 (45%), Gaps = 13/94 (13%)
Query: 17 HCSAAEGDIA----------KLTGILSHSPSLLNETSENGWTALMYAARNGHPEIVQFLL 66
H + A GD A + +L + + L SE G T LM AAR GH VQFL+
Sbjct: 591 HATTATGDTALTYACENGHTDVADVLLQAGADLEHESEGGRTPLMKAARAGHVCTVQFLI 650
Query: 67 EKGC--DRSIVNKSRQTALDIAVFWGYKHIANLL 98
KG +R+ N T L +A G+ + LL
Sbjct: 651 SKGANVNRTTANND-HTVLSLACAGGHLAVVELL 683
Score = 40.4 bits (93), Expect = 0.003
Identities = 27/80 (33%), Positives = 41/80 (51%), Gaps = 2/80 (2%)
Query: 19 SAAEGDIAKLTGILSHSPSLLNETSENGWTALMYAARNGHPEIVQFLLEKGCDRSIVNKS 78
SA ++A+L +L + + ++E +AL A GH E+V+FLLE G D+
Sbjct: 376 SAGHVEVARL--LLENGAGINTHSNEFKESALTLACYKGHLEMVRFLLEAGADQEHKTDE 433
Query: 79 RQTALDIAVFWGYKHIANLL 98
TAL A G+ +A LL
Sbjct: 434 MHTALMEACMDGHVEVARLL 453
Score = 38.5 bits (88), Expect = 0.013
Identities = 35/128 (27%), Positives = 54/128 (42%), Gaps = 23/128 (17%)
Query: 27 KLTGILSHSPSLLNETSENGWTALMYAARNGHPEIVQFLLEKGCDRSI--VNKSRQTALD 84
++ +L + + ++ G T LM AA G+ E+ + LL+KG D + V SR TAL
Sbjct: 1015 EVVSLLLDRKANVEHRAKTGLTPLMEAASGGYAEVGRVLLDKGADVNAPPVPSSRDTALT 1074
Query: 85 IAVFWGYKHIANLLATAKGGKKPWFLTNEVEECENYFSKTLLDRKSEKRNNSDWLLAKES 144
IA G+ LL +G +D +++K N WL A
Sbjct: 1075 IAADKGHYKFCELL-IGRGAH--------------------IDVRNKKGNTPLWLAANGG 1113
Query: 145 HPATVFIL 152
H V +L
Sbjct: 1114 HLDVVQLL 1121
Score = 37.4 bits (85), Expect = 0.029
Identities = 25/88 (28%), Positives = 42/88 (47%), Gaps = 2/88 (2%)
Query: 20 AAEGDIAKLTGILSHSPSLLNETSENGWTALMYAARNGHPEIVQFLLEKGCD-RSIVNKS 78
A G +L L + + + G+T L+ AA GH +V+ LL+ G D + ++
Sbjct: 839 ACAGGHEELVQTLLERGASIEHRDKKGFTPLILAATAGHVGVVEILLDNGADIEAQSERT 898
Query: 79 RQTALDIAVFWGYKHIANLLATAKGGKK 106
+ T L +A G + + LL A+G K
Sbjct: 899 KDTPLSLACSGGRQEVVELL-LARGANK 925
Score = 37.4 bits (85), Expect = 0.029
Identities = 22/83 (26%), Positives = 38/83 (45%)
Query: 19 SAAEGDIAKLTGILSHSPSLLNETSENGWTALMYAARNGHPEIVQFLLEKGCDRSIVNKS 78
+A G + + +L + + ++ T L A G E+V+ LL +G ++ N S
Sbjct: 872 AATAGHVGVVEILLDNGADIEAQSERTKDTPLSLACSGGRQEVVELLLARGANKEHRNVS 931
Query: 79 RQTALDIAVFWGYKHIANLLATA 101
T L +A GY +I +L A
Sbjct: 932 DYTPLSLAASGGYVNIIKILLNA 954
Score = 36.2 bits (82), Expect = 0.064
Identities = 23/68 (33%), Positives = 35/68 (51%), Gaps = 8/68 (11%)
Query: 48 TALMYAARNGHPEIVQFLLEKGCDRSIVNKSRQTALDIAVFWGYKHIANLLATA------ 101
T LM AA+ GH E+V++LL G + + TAL A G+ +A++L A
Sbjct: 566 TPLMEAAQEGHLELVKYLLAAGANVHATTATGDTALTYACENGHTDVADVLLQAGADLEH 625
Query: 102 --KGGKKP 107
+GG+ P
Sbjct: 626 ESEGGRTP 633
Score = 35.4 bits (80), Expect = 0.11
Identities = 20/65 (30%), Positives = 35/65 (53%), Gaps = 1/65 (1%)
Query: 19 SAAEGDIAKLTGILSHSPSLLNETSENGWTALMYAARNGHPEIVQFLLEKGCDRSIVNKS 78
+A EG + + +L+ ++ + T+ G TAL YA NGH ++ LL+ G D ++
Sbjct: 571 AAQEGHLELVKYLLAAGANV-HATTATGDTALTYACENGHTDVADVLLQAGADLEHESEG 629
Query: 79 RQTAL 83
+T L
Sbjct: 630 GRTPL 634
Score = 35.4 bits (80), Expect = 0.11
Identities = 21/58 (36%), Positives = 29/58 (50%)
Query: 41 ETSENGWTALMYAARNGHPEIVQFLLEKGCDRSIVNKSRQTALDIAVFWGYKHIANLL 98
+T N TAL A GH E+VQ LLE+G +K T L +A G+ + +L
Sbjct: 827 QTESNHDTALTLACAGGHEELVQTLLERGASIEHRDKKGFTPLILAATAGHVGVVEIL 884
Score = 35.0 bits (79), Expect = 0.14
Identities = 24/81 (29%), Positives = 41/81 (50%), Gaps = 2/81 (2%)
Query: 18 CSAAEGDIAKLTGILSHSPSLLNETSENGWTALMYAARNGHPEIVQFLLEKGCDRSIVNK 77
CSA ++A++ +L+ ++ + + T LM AA GH +IV+ LL D + +
Sbjct: 275 CSAGYYELAQV--LLAMHANVEDRGIKGDITPLMAAANGGHVKIVKLLLAHKADVNAQSS 332
Query: 78 SRQTALDIAVFWGYKHIANLL 98
+ TAL A GY + +L
Sbjct: 333 TGNTALTYACAGGYVDVVKVL 353
Score = 34.3 bits (77), Expect = 0.24
Identities = 18/51 (35%), Positives = 29/51 (56%)
Query: 48 TALMYAARNGHPEIVQFLLEKGCDRSIVNKSRQTALDIAVFWGYKHIANLL 98
TALM A +GH E+ + LL+ G ++ S ++ L +A G+ +A LL
Sbjct: 436 TALMEACMDGHVEVARLLLDSGAQVNMPADSFESPLTLAACGGHVELAALL 486
Score = 32.0 bits (71), Expect = 1.2
Identities = 18/54 (33%), Positives = 26/54 (48%)
Query: 48 TALMYAARNGHPEIVQFLLEKGCDRSIVNKSRQTALDIAVFWGYKHIANLLATA 101
TAL AA GH + + L+ +G + NK T L +A G+ + LL A
Sbjct: 1071 TALTIAADKGHYKFCELLIGRGAHIDVRNKKGNTPLWLAANGGHLDVVQLLVQA 1124
Score = 31.6 bits (70), Expect = 1.6
Identities = 20/76 (26%), Positives = 33/76 (43%)
Query: 19 SAAEGDIAKLTGILSHSPSLLNETSENGWTALMYAARNGHPEIVQFLLEKGCDRSIVNKS 78
+A G + + ++S ++ T+ N T L A GH +V+ LL G D + K
Sbjct: 637 AARAGHVCTVQFLISKGANVNRTTANNDHTVLSLACAGGHLAVVELLLAHGADPTHRLKD 696
Query: 79 RQTALDIAVFWGYKHI 94
T L A G+ +
Sbjct: 697 GSTMLIEAAKGGHTSV 712
Score = 31.2 bits (69), Expect = 2.1
Identities = 23/81 (28%), Positives = 38/81 (46%), Gaps = 3/81 (3%)
Query: 18 CSAAEGDIAKLTGILSHSPSLLNETSENGWTALMYAARNGHPEIVQFLLEKGCDRSIVNK 77
C ++A+L L S + +N +++ + L AA GH E+ L+E+G VN
Sbjct: 442 CMDGHVEVARL---LLDSGAQVNMPADSFESPLTLAACGGHVELAALLIERGASLEEVND 498
Query: 78 SRQTALDIAVFWGYKHIANLL 98
T L A G++ + LL
Sbjct: 499 EGYTPLMEAAREGHEEMVALL 519
Score = 31.2 bits (69), Expect = 2.1
Identities = 21/79 (26%), Positives = 36/79 (45%)
Query: 20 AAEGDIAKLTGILSHSPSLLNETSENGWTALMYAARNGHPEIVQFLLEKGCDRSIVNKSR 79
AA+ K +L + ++ ++ G T L AA GH ++VQ L++ G D + +
Sbjct: 1076 AADKGHYKFCELLIGRGAHIDVRNKKGNTPLWLAANGGHLDVVQLLVQAGADVDAADNRK 1135
Query: 80 QTALDIAVFWGYKHIANLL 98
T L A G+ + L
Sbjct: 1136 ITPLMAAFRKGHVKVVRYL 1154
>gi|224465233 euchromatic histone-lysine N-methyltransferase 1
isoform 1 [Homo sapiens]
Length = 1298
Score = 48.9 bits (115), Expect = 1e-05
Identities = 28/89 (31%), Positives = 44/89 (49%)
Query: 14 TQFHCSAAEGDIAKLTGILSHSPSLLNETSENGWTALMYAARNGHPEIVQFLLEKGCDRS 73
T H +A +G + +LS+ +N + GWT +++A H ++V+ LL KG D +
Sbjct: 841 TCLHLAAKKGHYEVVQYLLSNGQMDVNCQDDGGWTPMIWATEYKHVDLVKLLLSKGSDIN 900
Query: 74 IVNKSRQTALDIAVFWGYKHIANLLATAK 102
I + L A F G IA +L AK
Sbjct: 901 IRDNEENICLHWAAFSGCVDIAEILLAAK 929
Score = 33.5 bits (75), Expect = 0.42
Identities = 18/50 (36%), Positives = 27/50 (54%)
Query: 20 AAEGDIAKLTGILSHSPSLLNETSENGWTALMYAARNGHPEIVQFLLEKG 69
AAE + + L + +L++ G T L AA+ GH E+VQ+LL G
Sbjct: 813 AAENNHLEAVKYLIKAGALVDPKDAEGSTCLHLAAKKGHYEVVQYLLSNG 862
Score = 33.1 bits (74), Expect = 0.55
Identities = 22/80 (27%), Positives = 38/80 (47%)
Query: 19 SAAEGDIAKLTGILSHSPSLLNETSENGWTALMYAARNGHPEIVQFLLEKGCDRSIVNKS 78
+AAE + +L + + ++ SE+ T LM AA N H E V++L++ G +
Sbjct: 779 AAAEAGHVDICHMLVQAGANIDTCSEDQRTPLMEAAENNHLEAVKYLIKAGALVDPKDAE 838
Query: 79 RQTALDIAVFWGYKHIANLL 98
T L +A G+ + L
Sbjct: 839 GSTCLHLAAKKGHYEVVQYL 858
>gi|156142184 ankyrin repeat domain 39 [Homo sapiens]
Length = 183
Score = 48.5 bits (114), Expect = 1e-05
Identities = 28/80 (35%), Positives = 42/80 (52%), Gaps = 1/80 (1%)
Query: 19 SAAEGDIAKLTGILSHSPSLLNETSENGWTALMYAARNGHPEIVQFLLEKGCDRSIVNKS 78
+A GD+ ++ ++ + ++ G+TAL YA+RNGH + QFLLE G
Sbjct: 38 AALNGDLGRVKHLIQKAEDP-SQPDSAGYTALHYASRNGHYAVCQFLLESGAKCDAQTHG 96
Query: 79 RQTALDIAVFWGYKHIANLL 98
TAL A + G+ IA LL
Sbjct: 97 GATALHRASYCGHTEIARLL 116
Score = 35.0 bits (79), Expect = 0.14
Identities = 26/85 (30%), Positives = 40/85 (47%), Gaps = 1/85 (1%)
Query: 14 TQFHCSAAEGDIAKLTGILSHSPSLLNETSENGWTALMYAARNGHPEIVQFLLEKGCDRS 73
T H ++ G A + L S + + + G TAL A+ GH EI + LL G +
Sbjct: 66 TALHYASRNGHYA-VCQFLLESGAKCDAQTHGGATALHRASYCGHTEIARLLLSHGSNPR 124
Query: 74 IVNKSRQTALDIAVFWGYKHIANLL 98
+V+ T+L A G+ I +LL
Sbjct: 125 VVDDDGMTSLHKAAERGHGDICSLL 149
>gi|37221184 krev interaction trapped 1 isoform 1 [Homo sapiens]
Length = 736
Score = 47.8 bits (112), Expect = 2e-05
Identities = 34/101 (33%), Positives = 51/101 (50%), Gaps = 4/101 (3%)
Query: 1 MSSVKRSLKQEIVTQF--HCSAAEGDIAKLTGILSHSPSLLNETSENGWTALMYAARNGH 58
MSSV +++ V F H SA EGD L+ +LS S+ N+ + W + YA G
Sbjct: 275 MSSVTEDKERQWVDDFPLHRSACEGDSELLSRLLSERFSV-NQLDSDHWAPIHYACWYGK 333
Query: 59 PEIVQFLLEKG-CDRSIVNKSRQTALDIAVFWGYKHIANLL 98
E + LLEKG C+ +++N + L A G+ I +L
Sbjct: 334 VEATRILLEKGKCNPNLLNGQLSSPLHFAAGGGHAEIVQIL 374
>gi|37221182 krev interaction trapped 1 isoform 1 [Homo sapiens]
Length = 736
Score = 47.8 bits (112), Expect = 2e-05
Identities = 34/101 (33%), Positives = 51/101 (50%), Gaps = 4/101 (3%)
Query: 1 MSSVKRSLKQEIVTQF--HCSAAEGDIAKLTGILSHSPSLLNETSENGWTALMYAARNGH 58
MSSV +++ V F H SA EGD L+ +LS S+ N+ + W + YA G
Sbjct: 275 MSSVTEDKERQWVDDFPLHRSACEGDSELLSRLLSERFSV-NQLDSDHWAPIHYACWYGK 333
Query: 59 PEIVQFLLEKG-CDRSIVNKSRQTALDIAVFWGYKHIANLL 98
E + LLEKG C+ +++N + L A G+ I +L
Sbjct: 334 VEATRILLEKGKCNPNLLNGQLSSPLHFAAGGGHAEIVQIL 374
>gi|37221187 krev interaction trapped 1 isoform 1 [Homo sapiens]
Length = 736
Score = 47.8 bits (112), Expect = 2e-05
Identities = 34/101 (33%), Positives = 51/101 (50%), Gaps = 4/101 (3%)
Query: 1 MSSVKRSLKQEIVTQF--HCSAAEGDIAKLTGILSHSPSLLNETSENGWTALMYAARNGH 58
MSSV +++ V F H SA EGD L+ +LS S+ N+ + W + YA G
Sbjct: 275 MSSVTEDKERQWVDDFPLHRSACEGDSELLSRLLSERFSV-NQLDSDHWAPIHYACWYGK 333
Query: 59 PEIVQFLLEKG-CDRSIVNKSRQTALDIAVFWGYKHIANLL 98
E + LLEKG C+ +++N + L A G+ I +L
Sbjct: 334 VEATRILLEKGKCNPNLLNGQLSSPLHFAAGGGHAEIVQIL 374
>gi|31581522 krev interaction trapped 1 isoform 1 [Homo sapiens]
Length = 736
Score = 47.8 bits (112), Expect = 2e-05
Identities = 34/101 (33%), Positives = 51/101 (50%), Gaps = 4/101 (3%)
Query: 1 MSSVKRSLKQEIVTQF--HCSAAEGDIAKLTGILSHSPSLLNETSENGWTALMYAARNGH 58
MSSV +++ V F H SA EGD L+ +LS S+ N+ + W + YA G
Sbjct: 275 MSSVTEDKERQWVDDFPLHRSACEGDSELLSRLLSERFSV-NQLDSDHWAPIHYACWYGK 333
Query: 59 PEIVQFLLEKG-CDRSIVNKSRQTALDIAVFWGYKHIANLL 98
E + LLEKG C+ +++N + L A G+ I +L
Sbjct: 334 VEATRILLEKGKCNPNLLNGQLSSPLHFAAGGGHAEIVQIL 374
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.319 0.136 0.417
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 18,757,893
Number of Sequences: 37866
Number of extensions: 856711
Number of successful extensions: 3067
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 236
Number of HSP's successfully gapped in prelim test: 51
Number of HSP's that attempted gapping in prelim test: 1884
Number of HSP's gapped (non-prelim): 1137
length of query: 462
length of database: 18,247,518
effective HSP length: 106
effective length of query: 356
effective length of database: 14,233,722
effective search space: 5067205032
effective search space used: 5067205032
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.