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Search of human proteins with 6912676
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|6912676 SKI-interacting protein [Homo sapiens]
(536 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|6912676 SKI-interacting protein [Homo sapiens] 1076 0.0
gi|55741709 RNA binding motif protein 25 [Homo sapiens] 52 2e-06
gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo sa... 49 2e-05
gi|239754909 PREDICTED: hypothetical protein [Homo sapiens] 49 2e-05
gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-li... 48 2e-05
gi|78042577 MAP7 domain containing 1 [Homo sapiens] 48 2e-05
gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo sa... 47 6e-05
gi|239749449 PREDICTED: hypothetical protein [Homo sapiens] 46 1e-04
gi|116008442 zinc finger CCCH-type containing 13 [Homo sapiens] 46 1e-04
gi|239745079 PREDICTED: Putative golgin subfamily A member 6-lik... 45 1e-04
gi|41152097 DNA segment on chromosome X and Y (unique) 155 expre... 45 1e-04
gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-li... 45 2e-04
gi|239747134 PREDICTED: hypothetical protein XP_002343921 [Homo ... 44 3e-04
gi|148746195 trichohyalin [Homo sapiens] 44 4e-04
gi|50513245 chromatin assembly factor 1, subunit A (p150) [Homo ... 44 4e-04
gi|31377595 zinc finger CCCH-type containing 18 [Homo sapiens] 44 4e-04
gi|156766047 GRB10 interacting GYF protein 2 isoform c [Homo sap... 44 5e-04
gi|156766045 GRB10 interacting GYF protein 2 isoform a [Homo sap... 44 5e-04
gi|156766043 GRB10 interacting GYF protein 2 isoform b [Homo sap... 44 5e-04
gi|42476299 GRB10 interacting GYF protein 2 isoform b [Homo sapi... 44 5e-04
gi|239745153 PREDICTED: similar to Putative golgin subfamily A m... 44 5e-04
gi|239745127 PREDICTED: similar to Putative golgin subfamily A m... 44 5e-04
gi|194294523 intersectin 2 isoform 3 [Homo sapiens] 44 5e-04
gi|194294521 intersectin 2 isoform 1 [Homo sapiens] 44 5e-04
gi|194294525 intersectin 2 isoform 2 [Homo sapiens] 44 5e-04
gi|102467235 inner centromere protein antigens 135/155kDa isofor... 44 5e-04
gi|102467242 inner centromere protein antigens 135/155kDa isofor... 44 5e-04
gi|115298682 HBxAg transactivated protein 2 [Homo sapiens] 44 5e-04
gi|193788632 DnaJ (Hsp40) homolog, subfamily C, member 2 isoform... 43 6e-04
gi|154146223 splicing factor, arginine/serine-rich 130 [Homo sap... 43 6e-04
>gi|6912676 SKI-interacting protein [Homo sapiens]
Length = 536
Score = 1076 bits (2783), Expect = 0.0
Identities = 536/536 (100%), Positives = 536/536 (100%)
Query: 1 MALTSFLPAPTQLSQDQLEAEEKARSQRSRQTSLVSSRREPPPYGYRKGWIPRLLEDFGD 60
MALTSFLPAPTQLSQDQLEAEEKARSQRSRQTSLVSSRREPPPYGYRKGWIPRLLEDFGD
Sbjct: 1 MALTSFLPAPTQLSQDQLEAEEKARSQRSRQTSLVSSRREPPPYGYRKGWIPRLLEDFGD 60
Query: 61 GGAFPEIHVAQYPLDMGRKKKMSNALAIQVDSEGKIKYDAIARQGQSKDKVIYSKYTDLV 120
GGAFPEIHVAQYPLDMGRKKKMSNALAIQVDSEGKIKYDAIARQGQSKDKVIYSKYTDLV
Sbjct: 61 GGAFPEIHVAQYPLDMGRKKKMSNALAIQVDSEGKIKYDAIARQGQSKDKVIYSKYTDLV 120
Query: 121 PKEVMNADDPDLQRPDEEAIKEITEKTRVALEKSVSQKVAAAMPVRAADKLAPAQYIRYT 180
PKEVMNADDPDLQRPDEEAIKEITEKTRVALEKSVSQKVAAAMPVRAADKLAPAQYIRYT
Sbjct: 121 PKEVMNADDPDLQRPDEEAIKEITEKTRVALEKSVSQKVAAAMPVRAADKLAPAQYIRYT 180
Query: 181 PSQQGVAFNSGAKQRVIRMVEMQKDPMEPPRFKINKKIPRGPPSPPAPVMHSPSRKMTVK 240
PSQQGVAFNSGAKQRVIRMVEMQKDPMEPPRFKINKKIPRGPPSPPAPVMHSPSRKMTVK
Sbjct: 181 PSQQGVAFNSGAKQRVIRMVEMQKDPMEPPRFKINKKIPRGPPSPPAPVMHSPSRKMTVK 240
Query: 241 EQQEWKIPPCISNWKNAKGYTIPLDKRLAADGRGLQTVHINENFAKLAEALYIADRKARE 300
EQQEWKIPPCISNWKNAKGYTIPLDKRLAADGRGLQTVHINENFAKLAEALYIADRKARE
Sbjct: 241 EQQEWKIPPCISNWKNAKGYTIPLDKRLAADGRGLQTVHINENFAKLAEALYIADRKARE 300
Query: 301 AVEMRAQVERKMAQKEKEKHEEKLREMAQKARERRAGIKTHVEKEDGEARERDEIRHDRR 360
AVEMRAQVERKMAQKEKEKHEEKLREMAQKARERRAGIKTHVEKEDGEARERDEIRHDRR
Sbjct: 301 AVEMRAQVERKMAQKEKEKHEEKLREMAQKARERRAGIKTHVEKEDGEARERDEIRHDRR 360
Query: 361 KERQHDRNLSRAAPDKRSKLQRNENRDISEVIALGVPNPRTSNEVQYDQRLFNQSKGMDS 420
KERQHDRNLSRAAPDKRSKLQRNENRDISEVIALGVPNPRTSNEVQYDQRLFNQSKGMDS
Sbjct: 361 KERQHDRNLSRAAPDKRSKLQRNENRDISEVIALGVPNPRTSNEVQYDQRLFNQSKGMDS 420
Query: 421 GFAGGEDEIYNVYDQAWRGGKDMAQSIYRPSKNLDKDMYGDDLEARIKTNRFVPDKEFSG 480
GFAGGEDEIYNVYDQAWRGGKDMAQSIYRPSKNLDKDMYGDDLEARIKTNRFVPDKEFSG
Sbjct: 421 GFAGGEDEIYNVYDQAWRGGKDMAQSIYRPSKNLDKDMYGDDLEARIKTNRFVPDKEFSG 480
Query: 481 SDRRQRGREGPVQFEEDPFGLDKFLEEAKQHGGSKRPSDSSRPKEHEHEGKKRRKE 536
SDRRQRGREGPVQFEEDPFGLDKFLEEAKQHGGSKRPSDSSRPKEHEHEGKKRRKE
Sbjct: 481 SDRRQRGREGPVQFEEDPFGLDKFLEEAKQHGGSKRPSDSSRPKEHEHEGKKRRKE 536
>gi|55741709 RNA binding motif protein 25 [Homo sapiens]
Length = 843
Score = 51.6 bits (122), Expect = 2e-06
Identities = 57/262 (21%), Positives = 107/262 (40%), Gaps = 29/262 (11%)
Query: 293 IADRKAREAVEMRAQVERKMAQKEKEKHEEKLREMAQKARERRAGIKTHVEKEDGEARER 352
+ + K ++ E R ++E++ ++E+E+ E+ R ++ RER + E+E R+R
Sbjct: 291 LEEEKGKKEKE-RQEIEKERRERERERERERERREREREREREREREKEKERERERERDR 349
Query: 353 DEIR-------------HDRRKERQHDRNLSRAAPDKRSKLQRNENRDISEVIALGVPNP 399
D R DR +ER DRN R+ ++S+ R R+
Sbjct: 350 DRDRTKERDRDRDRERDRDRDRERSSDRNKDRSRSREKSR-DRERERERERERERERERE 408
Query: 400 RTSNEVQYDQRLFNQSKGMDSGFAGGEDEIYNVYDQAWRGGKDMAQSIYRPSKNLDKDMY 459
R + +R + + D EDE + Y++ + + + + + +
Sbjct: 409 REREREREREREREREREKDKKRDREEDE-EDAYER-----RKLERKLREKEAAYQERLK 462
Query: 460 GDDLEARIKTNRFVPDKEFSGSDRRQRGREGP--VQFEEDPFGLDKFLEEAKQHGGS--- 514
++ R KT + + E RR+ +E +F ED D ++ K + GS
Sbjct: 463 NWEIRERKKTREYEKEAEREEERRREMAKEAKRLKEFLED---YDDDRDDPKYYRGSALQ 519
Query: 515 KRPSDSSRPKEHEHEGKKRRKE 536
KR D + E + +KR KE
Sbjct: 520 KRLRDREKEMEADERDRKREKE 541
Score = 40.0 bits (92), Expect = 0.005
Identities = 28/102 (27%), Positives = 46/102 (45%), Gaps = 20/102 (19%)
Query: 303 EMRAQVERKMAQKEKEKHEEKLREMAQKARERRAGIKTHVEKEDG--------------- 347
E+R + + + +KE E+ EE+ REMA++A+ + ++ + + D
Sbjct: 465 EIRERKKTREYEKEAEREEERRREMAKEAKRLKEFLEDYDDDRDDPKYYRGSALQKRLRD 524
Query: 348 -----EARERDEIRHDRRKERQHDRNLSRAAPDKRSKLQRNE 384
EA ERD R E R L+ PD ++LQR E
Sbjct: 525 REKEMEADERDRKREKEELEEIRQRLLAEGHPDPDAELQRME 566
Score = 38.1 bits (87), Expect = 0.020
Identities = 23/93 (24%), Positives = 46/93 (49%), Gaps = 3/93 (3%)
Query: 295 DRKAREAVEMRAQVERKMAQKEKEKHEEKLREMAQKARERRAGIKTHVEKEDGEARERDE 354
D A E E + + + K ++ H++ E +K +ER+ K E+E RER+
Sbjct: 263 DINAIEMEEDKRDLISREISKFRDTHKKLEEEKGKKEKERQEIEKERRERERERERERER 322
Query: 355 IRHDRRKERQHDRNLSRAAPDKRSKLQRNENRD 387
+R +ER+ +R + ++ + +R+ +RD
Sbjct: 323 REREREREREREREKEK---ERERERERDRDRD 352
>gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo
sapiens]
Length = 668
Score = 48.5 bits (114), Expect = 2e-05
Identities = 50/259 (19%), Positives = 118/259 (45%), Gaps = 27/259 (10%)
Query: 282 ENFAKLAEALYIADRKAREAVEMRAQVERKMAQKEKEKHE-EKLREMAQKARERRAGIKT 340
E + E ++ + K R EM + E K+ + E++ HE EK+RE +K R+ I+
Sbjct: 349 EKMRRQEEMMWEKEEKMRRLEEMMWEKEEKIRELEEKMHEQEKIREQEEK-RQEEEKIRE 407
Query: 341 HVEKEDGEA---RERDEIRHDRRKERQHDRNLSRAAP--DKRSKLQRNENRDISEVIALG 395
++++ EA R+ ++IR K R+ ++ + R ++ K++ E R E +
Sbjct: 408 QEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMW-- 465
Query: 396 VPNPRTSNEVQYDQRLFNQSKGMDSGFAGGEDEIYNVYDQAWRGGKDMAQSIYRPSKNLD 455
R +++ + ++ Q + M +++I ++ WR + M + + +
Sbjct: 466 ----RQEEKIREQEEIWRQKEKMHE-----QEKIRKQEEKVWRQEEKMHDQEEKIREQEE 516
Query: 456 KDMYGDDLEARIKTNRFVPDKEFSGSDRRQRGREGPVQFEEDPFGLDKFLEEAKQHGGSK 515
K M+ + + R + +++ + + R +E +Q +E+ G + E+ ++ +
Sbjct: 517 K-MWRQEEKIREQ------EEKIREQEEKIREQEEMMQEQEEKMGEQE--EKMQEQEKMR 567
Query: 516 RPSDSSRPKEHEHEGKKRR 534
R + R +E + +K +
Sbjct: 568 RQEEKIREQEEKIREQKEK 586
Score = 42.4 bits (98), Expect = 0.001
Identities = 29/120 (24%), Positives = 60/120 (50%), Gaps = 15/120 (12%)
Query: 282 ENFAKLAEALYIADRKAREAVEMRAQVERKMAQKEKE--------KHEEKLREMAQKARE 333
E + E + + K RE EM + E KM ++E++ + EEK+RE +K RE
Sbjct: 523 EKIREQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMQEQEKMRRQEEKIREQEEKIRE 582
Query: 334 RRAGIKTHVEK---EDGEARERDEIRHDRRKE--RQHDR--NLSRAAPDKRSKLQRNENR 386
++ I+ EK ++ + RE++E+ ++ ++ Q ++ ++ K++R E +
Sbjct: 583 QKEKIREQEEKIWEQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEK 642
Score = 34.7 bits (78), Expect = 0.23
Identities = 22/93 (23%), Positives = 45/93 (48%), Gaps = 5/93 (5%)
Query: 282 ENFAKLAEALYIADRKAREAVEMRAQVERKMAQKEK-EKHEEKLREMAQKARERRAGIKT 340
E + E + ++ R+ ++R Q E+ QKEK + EEK+ E +K RE+ ++
Sbjct: 551 EKMGEQEEKMQEQEKMRRQEEKIREQEEKIREQKEKIREQEEKIWEQEEKIREQEEMMQE 610
Query: 341 HVEK----EDGEARERDEIRHDRRKERQHDRNL 369
EK E+ + ++++ K R+ + +
Sbjct: 611 QEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKM 643
Score = 31.6 bits (70), Expect = 1.9
Identities = 19/76 (25%), Positives = 40/76 (52%), Gaps = 5/76 (6%)
Query: 307 QVERKMAQKEK-EKHEEKLREMAQKARERRAGIKTHVEKEDGEARERDEIRHDRRKERQH 365
Q E+ Q+EK ++ EEK++E +K RE+ I+ EK R ++E+ ++ ++ +
Sbjct: 298 QEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEK----MRRQEEMMWEKEEKMRR 353
Query: 366 DRNLSRAAPDKRSKLQ 381
+ +K +L+
Sbjct: 354 QEEMMWEKEEKMRRLE 369
>gi|239754909 PREDICTED: hypothetical protein [Homo sapiens]
Length = 245
Score = 48.5 bits (114), Expect = 2e-05
Identities = 26/90 (28%), Positives = 50/90 (55%), Gaps = 1/90 (1%)
Query: 297 KAREAVEMRAQVERKMAQKEKEKHEEKLREMAQKARERRAGIKTHVEKEDGEARERDEIR 356
K RE E + + +++ +KE+E+ E++ +E ++ R R+ K KE E ++ + +
Sbjct: 156 KERERKERKKRERKQVGEKEEERKEKERKERKKRERNRKERKKERERKERRERKKERKKK 215
Query: 357 HDRRKERQHDRNLSRAAPDKRSKLQRNENR 386
+R+KERQ DR + +R K +R E +
Sbjct: 216 EERKKERQKDRQ-TNWREKERGKRERKERK 244
Score = 48.1 bits (113), Expect = 2e-05
Identities = 30/93 (32%), Positives = 50/93 (53%), Gaps = 3/93 (3%)
Query: 297 KAREAVEMRAQVERKMAQKEKEKHEEKLREMAQKARERR-AGIK--THVEKEDGEARERD 353
K RE E R + ERK +++KE+ E++ +K RER+ G K EKE E ++R+
Sbjct: 131 KERERKEERKREERKERERKKEEREKERERKERKKRERKQVGEKEEERKEKERKERKKRE 190
Query: 354 EIRHDRRKERQHDRNLSRAAPDKRSKLQRNENR 386
R +R+KER+ R K+ + ++ E +
Sbjct: 191 RNRKERKKERERKERRERKKERKKKEERKKERQ 223
Score = 43.9 bits (102), Expect = 4e-04
Identities = 26/94 (27%), Positives = 48/94 (51%), Gaps = 2/94 (2%)
Query: 296 RKAREAVEMRAQVERKMAQKEKE--KHEEKLREMAQKARERRAGIKTHVEKEDGEARERD 353
+K ++ + + ERK ++EKE + EEK + ++ +ER K E+E E R+R+
Sbjct: 83 KKEKKGERKKEERERKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKRE 142
Query: 354 EIRHDRRKERQHDRNLSRAAPDKRSKLQRNENRD 387
E + RK+ + ++ R KR + Q E +
Sbjct: 143 ERKERERKKEEREKERERKERKKRERKQVGEKEE 176
Score = 42.4 bits (98), Expect = 0.001
Identities = 25/95 (26%), Positives = 47/95 (49%), Gaps = 3/95 (3%)
Query: 296 RKAREAVEMRAQVERKMAQKEKEKHEEKLREMAQKARERRAGIKTHVEKEDGEARERDEI 355
R ++E E + ERK +E+ K E+ +E +K RER+ K ++ + ER E
Sbjct: 125 RTSKEGKERERKEERK---REERKERERKKEEREKERERKERKKRERKQVGEKEEERKEK 181
Query: 356 RHDRRKERQHDRNLSRAAPDKRSKLQRNENRDISE 390
RK+R+ +R + +++ + +R + R E
Sbjct: 182 ERKERKKRERNRKERKKERERKERRERKKERKKKE 216
Score = 41.2 bits (95), Expect = 0.002
Identities = 24/92 (26%), Positives = 42/92 (45%)
Query: 295 DRKAREAVEMRAQVERKMAQKEKEKHEEKLREMAQKARERRAGIKTHVEKEDGEARERDE 354
+RK R + + E K +K+KEK E K RER+ K KE +E E
Sbjct: 96 ERKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKERERKKEERE 155
Query: 355 IRHDRRKERQHDRNLSRAAPDKRSKLQRNENR 386
+R++ ++ +R ++R + +R E +
Sbjct: 156 KERERKERKKRERKQVGEKEEERKEKERKERK 187
Score = 39.3 bits (90), Expect = 0.009
Identities = 47/244 (19%), Positives = 92/244 (37%), Gaps = 39/244 (15%)
Query: 293 IADRKAREAVEMRAQVERKMAQKEKEKHEEKLREMAQKARERRAGIKTHVEKEDGEARER 352
I +R+ + ER+ +K++ + EK + +K R+R G K ++ GE ++
Sbjct: 38 IREREREIETRKEGKKERESERKKERREREKRKREREKERKRERGKK----EKKGERKKE 93
Query: 353 DEIRHDRRKERQHDRNLSRAAPDKRSKLQRNENRDISEVIALGVPNPRTSNEVQYDQRLF 412
+ R RR+E+++ + K+ K +R RTS E + +R
Sbjct: 94 ERERKKRRREKENKEGEEKEKRKKKEKKERG----------------RTSKEGKERERKE 137
Query: 413 NQSKGMDSGFAGGEDEIYNVYDQAWRGGKDMAQSIYRPSKNLDKDMYGDDLEARIKTNRF 472
+ + ++E ++ R ++ Q + + +K+ R NR
Sbjct: 138 ERKREERKERERKKEEREKERERKERKKRERKQVGEKEEERKEKERKERKKRER---NRK 194
Query: 473 VPDKEFSGSDRRQRGREGPVQFEEDPFGLDKFLEEAKQHGGSKRPSDSSRPKEHEHEGKK 532
KE +RR+R +E + K+ +R D + GK+
Sbjct: 195 ERKKERERKERRERKKE----------------RKKKEERKKERQKDRQTNWREKERGKR 238
Query: 533 RRKE 536
RKE
Sbjct: 239 ERKE 242
Score = 30.0 bits (66), Expect = 5.5
Identities = 18/69 (26%), Positives = 35/69 (50%), Gaps = 1/69 (1%)
Query: 295 DRKAREAVEMRAQVE-RKMAQKEKEKHEEKLREMAQKARERRAGIKTHVEKEDGEARERD 353
+RK +E E + + RK +KE+E+ E + R+ +K +E R + + + +ER
Sbjct: 177 ERKEKERKERKKRERNRKERKKERERKERRERKKERKKKEERKKERQKDRQTNWREKERG 236
Query: 354 EIRHDRRKE 362
+ RK+
Sbjct: 237 KRERKERKK 245
>gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-like
[Homo sapiens]
Length = 828
Score = 48.1 bits (113), Expect = 2e-05
Identities = 50/250 (20%), Positives = 101/250 (40%), Gaps = 23/250 (9%)
Query: 289 EALYIADRKAREAVEMRAQVERKMAQKEKEKHEEKLREMAQKARERRAGIKTHVEKEDGE 348
E ++ D + RE E + E+ Q+EK + EE++RE +K RE +T E+E+
Sbjct: 359 ERMWEQDERLREKEERMREQEKMWEQEEKMQEEERIREREKKMREEE---ETMREQEEKM 415
Query: 349 ARERDEIRHDRRKERQHDRNLSRAAPDKRSKLQRNENRDISEVIALGVPNPRTSNEVQYD 408
++ + + KE Q R P+++ KL E E +++
Sbjct: 416 QKQEENMWEQEEKEWQQQR-----LPEQKEKLWEQEKMQEQEEKIW-----EQEEKIRDQ 465
Query: 409 QRLFNQSKGMDSGFAGGEDEIYNVYDQAWRGGKDMAQSIYRPSKNLDKD--MYGDDLEAR 466
+ ++ Q K M ++++ DQ W + M + K D++ M+ D R
Sbjct: 466 EEMWGQEKKM-----WRQEKMREQEDQMWEQEEKMRD---QEQKMWDQEERMWEQDERLR 517
Query: 467 IKTNRFVPDKEFSGSDRRQRGREGPVQFEEDPFGLDKFLEEAKQHGGSKRPSDSSRPKEH 526
K R K+ + + R + + E+ + ++ + E ++ ++
Sbjct: 518 EKEERMREQKKMWQQEEKMREEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMR 577
Query: 527 EHEGKKRRKE 536
E E K + +E
Sbjct: 578 EQEEKMQEQE 587
Score = 42.7 bits (99), Expect = 8e-04
Identities = 45/245 (18%), Positives = 106/245 (43%), Gaps = 34/245 (13%)
Query: 296 RKAREAVEMRAQVERKMAQKEKEKHEEKLREMAQKARERRAGI---KTHVEKEDGEARER 352
RK A + QV+ Q+E + EE+LRE +K R++ + + + +++G+ RE+
Sbjct: 215 RKLERAKFLLPQVQTNTLQEEMWRQEEELREQEKKIRKQEEKMWRQEERLREQEGKMREQ 274
Query: 353 DE-IRHDRRKERQHDRNLSRAAPDKRSKLQRNENRDISEVIALGVPNPRTSNEVQYDQRL 411
+E +R ++ R+ ++ L + R + + E + + + ++++
Sbjct: 275 EEKMRRQEKRLREQEKELREQEKELREQKKLREQEEQMQ---------------EQEEKM 319
Query: 412 FNQSKGMDSGFAGGEDEIYNVYDQAWRGGKDMAQSIYRPSKNLDKDMYGDDLEARIKTNR 471
+ Q + M E++++ ++ W K M + + ++ ++ M+ D R K R
Sbjct: 320 WEQEEKMRE----QEEKMWRQEERLWEQEKQMREQ-EQKMRDQEERMWEQDERLREKEER 374
Query: 472 FVPDKEFSGSDRRQRGREGPVQFEEDPFGLDKFLEEAKQHGGSKRPSDSSRPKEHEHEGK 531
+ +E +Q EE +K + E ++ + R + K+ E+ +
Sbjct: 375 M-------REQEKMWEQEEKMQEEERIREREKKMREEEE---TMREQEEKMQKQEENMWE 424
Query: 532 KRRKE 536
+ KE
Sbjct: 425 QEEKE 429
Score = 38.9 bits (89), Expect = 0.012
Identities = 40/247 (16%), Positives = 102/247 (41%), Gaps = 15/247 (6%)
Query: 289 EALYIADRKAREAVEMRAQVERKMAQKEKEKHEEKLREMAQKA--RERRAGIKTHVEKED 346
E ++ D + RE E + ++ Q+EK + E+K +E +K +E + + + + +
Sbjct: 507 ERMWEQDERLREKEERMREQKKMWQQEEKMREEKKTQEQEKKTWDQEEKMREEERMRERE 566
Query: 347 GEARERDEIRHDRRKERQHDRNLSRAAPDK----RSKLQRNENRDISEVIALGVPNPRTS 402
+ RE +E+ ++ ++ Q R +K K+Q E + + +
Sbjct: 567 KKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEEDK 626
Query: 403 NEVQYDQRLFNQSKGM--DSGFAGGEDEIYNVYDQAWRGGKDMAQSIYRPSKNLDKDMYG 460
+ Q ++ ++ Q + M ++E ++ R ++ Q + ++ M G
Sbjct: 627 MQEQ-EEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMREQEEKMQG 685
Query: 461 DDLEARIKTNRFVPDKEFSGSDRRQRGREGPVQFEEDPFGLDKFLEEAKQHGGSKRPSDS 520
+ + R + +++ G + + G+E + +E+ + + E ++ ++
Sbjct: 686 QEEKMREQ------EEKMRGQEEKMWGQEEKMWGQEEKMWGQEEMREKEERIRDQKEKMQ 739
Query: 521 SRPKEHE 527
R EHE
Sbjct: 740 ERLPEHE 746
Score = 35.8 bits (81), Expect = 0.10
Identities = 55/278 (19%), Positives = 107/278 (38%), Gaps = 41/278 (14%)
Query: 295 DRKAREAVEMRAQVERKMAQKEKE-KHEEKLREMAQK--------------ARERRAGIK 339
+++ RE ++R Q E+ Q+EK + EEK+RE +K RE+ ++
Sbjct: 296 EKELREQKKLREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMR 355
Query: 340 THVEK---EDGEARERDE-IRHDRRKERQHDRNLSRAAPDKRSKLQRNEN---RDISEVI 392
E+ +D RE++E +R + Q ++ +R K R E R+ E +
Sbjct: 356 DQEERMWEQDERLREKEERMREQEKMWEQEEKMQEEERIREREKKMREEEETMREQEEKM 415
Query: 393 ALGVPNPRTSNEVQYDQ--------RLFNQSKGMDSGFAGGEDEIYNVYDQAWRGGKDMA 444
N E ++ Q +L+ Q K + E E + DQ G++
Sbjct: 416 QKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQE-EKIRDQEEMWGQEKK 474
Query: 445 QSIYRPSKNLDKDMYGDDLEARIKTNRFVPDKEFSGS------DRRQRGREGPVQFEEDP 498
+ + M+ + + R + + +E ++ +R RE ++++
Sbjct: 475 MWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMWEQDERLREKEERMREQKKMWQQE- 533
Query: 499 FGLDKFLEEAKQHGGSKRPSDSSRPKEHEHEGKKRRKE 536
+K EE K K+ D E ++R K+
Sbjct: 534 ---EKMREEKKTQEQEKKTWDQEEKMREEERMREREKK 568
Score = 33.1 bits (74), Expect = 0.66
Identities = 21/105 (20%), Positives = 50/105 (47%), Gaps = 3/105 (2%)
Query: 282 ENFAKLAEALYIADRKAREAVEMRAQVERKMAQKEKEKHEEKLREMAQKARERRAGIKTH 341
E + E ++ + K +E E + E KM ++E+E ++ EM + E+ +
Sbjct: 588 EKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEEDKMQEQEEMMWEQEEKMQEQEEK 647
Query: 342 VEKEDGEARERDEIRHDRRKERQHDRNLSRAAPDKRSKLQRNENR 386
+ +++ + RE++E ++ ++ Q R ++ K+Q E +
Sbjct: 648 MWEQEEKMREQEEKMREQEEKMQGQEEKMR---EQEEKMQGQEEK 689
Score = 31.2 bits (69), Expect = 2.5
Identities = 46/252 (18%), Positives = 107/252 (42%), Gaps = 24/252 (9%)
Query: 286 KLAEALYIADRKAREAV-EMRAQVERKMAQKEKEKHEEK-LREMAQKARERRAGIKTHVE 343
K E ++ + + RE +MR Q E+ Q+++ + +EK LRE ++ RE+ K E
Sbjct: 252 KQEEKMWRQEERLREQEGKMREQEEKMRRQEKRLREQEKELREQEKELREQ----KKLRE 307
Query: 344 KEDGEARERDEIRHDRRKERQHDRNLSRA-----APDKRSKLQRNENRDISEVIALGVPN 398
+E+ + +++ K R+ + + R +K+ + Q + RD E +
Sbjct: 308 QEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDER 367
Query: 399 PRTSNE-VQYDQRLFNQSKGMDSGFAGGEDEIYNVYDQAWRGGKDMAQSIYRPSKNLDKD 457
R E ++ ++++ Q + M E+E ++ R ++ + + +++
Sbjct: 368 LREKEERMREQEKMWEQEEKMQ------EEERIREREKKMREEEETMREQEEKMQKQEEN 421
Query: 458 MYGDDLEARIKTNRFVPDKEFSGSDRRQRGREGPVQFEEDPFGLDKFLEEAKQHGGSKRP 517
M+ + E + R KE + + +E + +E +K ++ + G K+
Sbjct: 422 MWEQE-EKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQE-----EKIRDQEEMWGQEKKM 475
Query: 518 SDSSRPKEHEHE 529
+ +E E +
Sbjct: 476 WRQEKMREQEDQ 487
Score = 29.3 bits (64), Expect = 9.5
Identities = 20/83 (24%), Positives = 40/83 (48%), Gaps = 3/83 (3%)
Query: 282 ENFAKLAEALYIADRKAREAVEMRAQVERKMAQKEKEKHEEKLREMAQKARERRAGIKTH 341
E + E + + E E Q +R QKEK +EK++E +K E+ I+
Sbjct: 406 ETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIR-- 463
Query: 342 VEKEDGEARERDEIRHDRRKERQ 364
++E+ +E+ R ++ +E++
Sbjct: 464 -DQEEMWGQEKKMWRQEKMREQE 485
>gi|78042577 MAP7 domain containing 1 [Homo sapiens]
Length = 841
Score = 48.1 bits (113), Expect = 2e-05
Identities = 59/242 (24%), Positives = 89/242 (36%), Gaps = 42/242 (17%)
Query: 181 PSQQGVAFNSGAKQRVIRMVEMQKDPM--------EPPRFKINKKIPRGPPSPPAPVMHS 232
PS +G + K RV R E ++ P + R N+K P SP S
Sbjct: 495 PSPRGTT--ASPKGRVRRKEEAKESPSAAGPEDKSQSKRRASNEKESAAPASPAPSPAPS 552
Query: 233 PSRKMTVKEQQEWKIPPCISNWKNAKGYTIPLDKRLAADGRGLQTVHINENFAKLAEALY 292
P+ KEQ + P + + P+ G T E LAE
Sbjct: 553 PTPAPPQKEQPPAETPTDAAVLTSPPAPAPPVTPSKPMAG----TTDREEATRLLAEKR- 607
Query: 293 IADRKAREAVEMRAQVERKMAQKEKEKHEEKLREMAQKARERRAGIKTHVE--------- 343
R+ARE E Q R A+++K EE+L A+ ER A + E
Sbjct: 608 ---RQAREQREREEQERRLQAERDKRMREEQLAREAEARAEREAEARRREEQEAREKAQA 664
Query: 344 -----------KEDGEARERDEIRHDRRKERQHDRNLSRAAPDKRSKLQ----RNENRDI 388
KE+ EAR R+E R + +H + + ++R +L+ R ++
Sbjct: 665 EQEEQERLQKQKEEAEARSREEAERQRLEREKHFQQQEQERQERRKRLEEIMKRTRKSEV 724
Query: 389 SE 390
SE
Sbjct: 725 SE 726
Score = 31.6 bits (70), Expect = 1.9
Identities = 59/228 (25%), Positives = 88/228 (38%), Gaps = 34/228 (14%)
Query: 129 DPDLQRPDEEA-IKEITEKTRVALEKSVSQKVAAAMPVRAADKLAPAQYIRYTPSQQGVA 187
DP P A + + T A++ + S K P + ++ P R P Q+
Sbjct: 32 DPSPPPPPMSALVPDTPPDTPPAMKNATSSKQLPLEPESPSGQVGP----RPAPPQEESP 87
Query: 188 FNSGAKQRVIRMVEMQKDPMEPPRFKINKKIPRGPPSPPA-PVMHSPSRKMTVKEQQEWK 246
+S AK R M PPR PSP A P SP K VK+ E
Sbjct: 88 -SSEAKSRGPTPPAMGPRDARPPRRS-------SQPSPTAVPASDSPPTKQEVKKAGE-- 137
Query: 247 IPPCISNWKNAKGYTIPLDKRLAADGRGLQTVHIN-ENFAKLAEALYIADRKAREAVEMR 305
K AK K LAA + V + E AK + +R+ R
Sbjct: 138 ------RHKLAKERREERAKYLAAK----KAVWLEKEEKAKALREKQLQERRRR------ 181
Query: 306 AQVERKMAQKEKEKHEEKLREMAQKARER-RAGIKTHVEKEDGEARER 352
+ +R A++ + EE+ R+ +K +ER A I+ V+K E R++
Sbjct: 182 LEEQRLKAEQRRAALEERQRQKLEKNKERYEAAIQRSVKKTWAEIRQQ 229
>gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo
sapiens]
Length = 750
Score = 46.6 bits (109), Expect = 6e-05
Identities = 51/276 (18%), Positives = 121/276 (43%), Gaps = 32/276 (11%)
Query: 282 ENFAKLAEALYIADRKAREAVEMRAQVERKMAQKEKEKHE-EKLREMAQKARERRAGIKT 340
E + E ++ + K R EM + E K+ + E++ HE EK+RE +K R+ I+
Sbjct: 363 EKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEK-RQEEEKIRE 421
Query: 341 HVEKEDGEA---RERDEIRHDRRKERQHDRNLSRAAP--DKRSKLQRNENRDISEVIALG 395
++++ EA R+ ++IR K R+ ++ + R ++ K++ E R E +
Sbjct: 422 QEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMW-- 479
Query: 396 VPNPRTSNEVQYDQRLFNQSKGMDSGFAGGEDEIYNVYDQAWRGG----------KDMAQ 445
R ++ + ++ Q + M E++I ++ WR ++ +
Sbjct: 480 ----RQEEKIHEQEEIWRQKEKMHE----QEEKIRKQEEKVWRQEEKIREQEEKIREQEE 531
Query: 446 SIYRPSKNL--DKDMYGDDLEARIKTNRFVPDKEFSGSDRRQRGREGPVQFEEDPFGLDK 503
++R + + ++M+ ++ + + + +K D+ R E + EE + ++
Sbjct: 532 KMWRQEEKIREQEEMWREEEKMHEQEKIWEEEKRQEQEDKMWRQEEKIREQEEKVWRQEE 591
Query: 504 FL---EEAKQHGGSKRPSDSSRPKEHEHEGKKRRKE 536
+ EE +Q K + +E E + +++ ++
Sbjct: 592 KIREQEEKRQEQEEKMWKQEEKIREQEEKIQEQEEK 627
Score = 36.2 bits (82), Expect = 0.077
Identities = 29/118 (24%), Positives = 53/118 (44%), Gaps = 10/118 (8%)
Query: 282 ENFAKLAEALYIADRKAREAVEMRAQVERKMAQKEK---------EKHEEKLREMAQKAR 332
E + E ++ + K RE E R + E KM ++E+ ++ EEK+RE +K R
Sbjct: 577 EKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQEEKIREQEEKIQEQEEKIREQEEKIR 636
Query: 333 ERRAGIKTHVEKEDGEARERDEIRHDRRKERQHDRNLSRAAPDKRSKLQRNENRDISE 390
E+ + EK GE E+ + ++ +E++ ++ K R + I E
Sbjct: 637 EQEEMTQEQEEKM-GEQEEKMCEQEEKMQEQEETMWRQEEKIREQEKKIREQEEKIRE 693
Score = 34.3 bits (77), Expect = 0.29
Identities = 25/112 (22%), Positives = 48/112 (42%), Gaps = 8/112 (7%)
Query: 282 ENFAKLAEALYIADRKAREAVEMRAQVERKMAQKEK-------EKHEEKLREMAQKARER 334
E + E ++ + K RE EM + E KM ++EK ++ E+K+ +K RE+
Sbjct: 524 EKIREQEEKMWRQEEKIREQEEMWRE-EEKMHEQEKIWEEEKRQEQEDKMWRQEEKIREQ 582
Query: 335 RAGIKTHVEKEDGEARERDEIRHDRRKERQHDRNLSRAAPDKRSKLQRNENR 386
+ EK + +R E K+ + R ++ K++ E +
Sbjct: 583 EEKVWRQEEKIREQEEKRQEQEEKMWKQEEKIREQEEKIQEQEEKIREQEEK 634
Score = 32.0 bits (71), Expect = 1.5
Identities = 21/79 (26%), Positives = 42/79 (53%), Gaps = 8/79 (10%)
Query: 307 QVERKMAQKEK-EKHEEKLREMAQKARERRAGIKTHVEKEDGEARERDEIRHDRRKERQH 365
Q E+ Q+EK ++ EEK++E +K RE+ I+ EK R ++E+ ++ ++ +
Sbjct: 298 QEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEK----MRRQEEMMWEKEEKMRR 353
Query: 366 DRNLSRAAPDKRSKLQRNE 384
+ +K K++R E
Sbjct: 354 QEEMMW---EKEEKMRRQE 369
Score = 32.0 bits (71), Expect = 1.5
Identities = 30/118 (25%), Positives = 52/118 (44%), Gaps = 11/118 (9%)
Query: 282 ENFAKLAEALYIADRKAREAVE-MRAQVERKMAQKEKEKHEEKLREMAQKARERRAGIKT 340
E + E + + K RE E MR Q E ++EK + +E++ M +K + R +
Sbjct: 314 EKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEM--MWEKEEKMRRQEEM 371
Query: 341 HVEKEDGEARERDEIRHDRRK-----ERQHDRNLSRAAPDKR---SKLQRNENRDISE 390
EKE+ R+ + + K E+ H++ R +KR K++ E R E
Sbjct: 372 MWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQE 429
Score = 32.0 bits (71), Expect = 1.5
Identities = 21/99 (21%), Positives = 45/99 (45%), Gaps = 1/99 (1%)
Query: 289 EALYIADRKAREAVEMRAQVERKMAQKEKE-KHEEKLREMAQKARERRAGIKTHVEKEDG 347
E ++ +++ + +M Q E+ Q+EK + EEK+RE +K +E+ + EK
Sbjct: 557 EKIWEEEKRQEQEDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQEEKIRE 616
Query: 348 EARERDEIRHDRRKERQHDRNLSRAAPDKRSKLQRNENR 386
+ + E R++ + R ++ K+ E +
Sbjct: 617 QEEKIQEQEEKIREQEEKIREQEEMTQEQEEKMGEQEEK 655
Score = 31.2 bits (69), Expect = 2.5
Identities = 18/80 (22%), Positives = 40/80 (50%), Gaps = 5/80 (6%)
Query: 295 DRKAREAVEMRAQVERKMAQKEK-EKHEEKLREMAQKARERRAGIKTHVEK----EDGEA 349
++ + +M+ Q E Q+EK + E+K+RE +K RE+ ++ EK E+
Sbjct: 654 EKMCEQEEKMQEQEETMWRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMC 713
Query: 350 RERDEIRHDRRKERQHDRNL 369
+ ++++ K R+ + +
Sbjct: 714 EQEEKMQEQEEKMRRQEEKM 733
Score = 30.4 bits (67), Expect = 4.2
Identities = 49/273 (17%), Positives = 111/273 (40%), Gaps = 31/273 (11%)
Query: 295 DRKAREAVEMRAQVERKMAQKEK-EKHEEKLREMAQKARERRAGIKTHVEKEDGEARE-- 351
+ K RE + + Q + Q+EK + EEK+RE +K + I + + E R+
Sbjct: 416 EEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQ 475
Query: 352 -----RDEIRHD-----RRKERQHDRNLSRAAPDKRSKLQRNENRDISEVIALGVPNP-R 400
++E H+ R+KE+ H++ +++ Q + R+ E I R
Sbjct: 476 EEMWRQEEKIHEQEEIWRQKEKMHEQEEKIRKQEEKVWRQEEKIREQEEKIREQEEKMWR 535
Query: 401 TSNEVQYDQRLFNQSKGM-DSGFAGGEDEIYNVYDQAWRGG---KDMAQSIYRPSKNL-- 454
+++ + ++ + + M + E++ D+ WR ++ + ++R + +
Sbjct: 536 QEEKIREQEEMWREEEKMHEQEKIWEEEKRQEQEDKMWRQEEKIREQEEKVWRQEEKIRE 595
Query: 455 --------DKDMYGDDLEARIKTNRFVPDKE-FSGSDRRQRGREGPVQFEEDPFG--LDK 503
++ M+ + + R + + +E + + R +E Q +E+ G +K
Sbjct: 596 QEEKRQEQEEKMWKQEEKIREQEEKIQEQEEKIREQEEKIREQEEMTQEQEEKMGEQEEK 655
Query: 504 FLEEAKQHGGSKRPSDSSRPKEHEHEGKKRRKE 536
E+ ++ + K E E K R +E
Sbjct: 656 MCEQEEKMQEQEETMWRQEEKIREQEKKIREQE 688
>gi|239749449 PREDICTED: hypothetical protein [Homo sapiens]
Length = 275
Score = 45.8 bits (107), Expect = 1e-04
Identities = 28/96 (29%), Positives = 48/96 (50%), Gaps = 5/96 (5%)
Query: 295 DRKAREAVEMRAQVERKMAQKEKEKHEEKLREMAQKARERRAGIKTHVEKEDGEARERDE 354
+RK +E + R ER+ ++ K K E+K RE Q+ R R K E+E + R+
Sbjct: 76 ERKRKEREKQRK--ERREKERRKRKKEKKKRERKQRGRRERKKKKERKERERENKQRRER 133
Query: 355 IRHDRRKE---RQHDRNLSRAAPDKRSKLQRNENRD 387
R RRK+ ++ R R +++ K ++ E R+
Sbjct: 134 KRKKRRKKKRRKERKREKERGKRERKRKKRKKEERE 169
Score = 45.1 bits (105), Expect = 2e-04
Identities = 26/101 (25%), Positives = 53/101 (52%), Gaps = 4/101 (3%)
Query: 295 DRKAREAVEMRAQVERKMAQKEKEKHEEKLREMAQKARERRAGIKTHVEKEDGEARERDE 354
+RK RE + + ++ +++K++ +E+ RE + RER+ + E+E R R E
Sbjct: 119 ERKERERENKQRRERKRKKRRKKKRRKERKREKERGKRERKRKKRKKEEREKKRERNRKE 178
Query: 355 IRHDR----RKERQHDRNLSRAAPDKRSKLQRNENRDISEV 391
+ +R R+ER+ +R R +R K ++ + + S+V
Sbjct: 179 RKKERERKERRERKKERKKERRKKKERKKDRKTDRQTDSQV 219
Score = 43.5 bits (101), Expect = 5e-04
Identities = 29/90 (32%), Positives = 48/90 (53%), Gaps = 6/90 (6%)
Query: 295 DRKAREAVEMRAQVERKMAQKEKEKHEEKLREMAQKARERRAGIKTHVEKEDGEARERDE 354
+R+ RE + + ERK + +KEK + K RE K RER+ + EK+ E RE++
Sbjct: 39 ERREREKRKREREKERKRERGKKEKKKRKKRERG-KERERK---RKEREKQRKERREKE- 93
Query: 355 IRHDRRKERQHDRNLSRAAPDKRSKLQRNE 384
R R+KE++ R +++ K +R E
Sbjct: 94 -RRKRKKEKKKRERKQRGRRERKKKKERKE 122
Score = 41.6 bits (96), Expect = 0.002
Identities = 22/92 (23%), Positives = 49/92 (53%), Gaps = 1/92 (1%)
Query: 295 DRKAREAVEMRAQVERKMAQKEKEKHEEKLREMAQKARERRAGIKTHVEKEDGEARERDE 354
+RK R E + + ERK ++E ++ E+ R+ +K ++RR K E+ E + +
Sbjct: 105 ERKQRGRRERKKKKERKERERENKQRRERKRKKRRK-KKRRKERKREKERGKRERKRKKR 163
Query: 355 IRHDRRKERQHDRNLSRAAPDKRSKLQRNENR 386
+ +R K+R+ +R + +++ + +R + R
Sbjct: 164 KKEEREKKRERNRKERKKERERKERRERKKER 195
Score = 40.4 bits (93), Expect = 0.004
Identities = 26/79 (32%), Positives = 46/79 (58%), Gaps = 4/79 (5%)
Query: 296 RKAREAVEMRAQVERKMAQKEKEKHE---EKLREMAQKARERRAGIKTHVEKEDGEARER 352
RK R+ + R + ERK +++KE+ E E+ R+ +K RER+ + E++ E R++
Sbjct: 144 RKERKREKERGKRERKRKKRKKEEREKKRERNRKERKKERERKERRERKKERKK-ERRKK 202
Query: 353 DEIRHDRRKERQHDRNLSR 371
E + DR+ +RQ D + R
Sbjct: 203 KERKKDRKTDRQTDSQVFR 221
Score = 39.7 bits (91), Expect = 0.007
Identities = 20/92 (21%), Positives = 49/92 (53%), Gaps = 1/92 (1%)
Query: 296 RKAREAVEMRAQVERKMAQKEKEKHEEKLREMAQKARER-RAGIKTHVEKEDGEARERDE 354
+K +E E + +++ +K K++ ++K R+ ++ +ER + K K++ ++R+
Sbjct: 115 KKKKERKERERENKQRRERKRKKRRKKKRRKERKREKERGKRERKRKKRKKEEREKKRER 174
Query: 355 IRHDRRKERQHDRNLSRAAPDKRSKLQRNENR 386
R +R+KER+ R K+ + ++ E +
Sbjct: 175 NRKERKKERERKERRERKKERKKERRKKKERK 206
Score = 39.3 bits (90), Expect = 0.009
Identities = 23/94 (24%), Positives = 46/94 (48%), Gaps = 2/94 (2%)
Query: 296 RKAREAVEMRAQVERKMAQKEKEKHEEKLREMAQKARERRAGIKTHVEKEDGEARERD-- 353
RK + R Q R+ +K+KE+ E + ++ R+R+ K KE +ER
Sbjct: 97 RKKEKKKRERKQRGRRERKKKKERKERERENKQRRERKRKKRRKKKRRKERKREKERGKR 156
Query: 354 EIRHDRRKERQHDRNLSRAAPDKRSKLQRNENRD 387
E + +RK+ + ++ R +++ + +R E R+
Sbjct: 157 ERKRKKRKKEEREKKRERNRKERKKERERKERRE 190
Score = 38.5 bits (88), Expect = 0.016
Identities = 21/79 (26%), Positives = 40/79 (50%), Gaps = 1/79 (1%)
Query: 309 ERKMAQKEKEKHEEKLREMAQKARERRAGIKTHVEKEDGE-ARERDEIRHDRRKERQHDR 367
+R+ +K++ + EK + +K R+R G K +++ E +ER+ R +R K+R+ R
Sbjct: 31 QRESERKKERREREKRKREREKERKRERGKKEKKKRKKRERGKERERKRKEREKQRKERR 90
Query: 368 NLSRAAPDKRSKLQRNENR 386
R K K + + R
Sbjct: 91 EKERRKRKKEKKKRERKQR 109
Score = 38.5 bits (88), Expect = 0.016
Identities = 25/79 (31%), Positives = 43/79 (54%), Gaps = 8/79 (10%)
Query: 309 ERKMAQKEKEKHEEKLREMAQKARERRAGIKTHVEKEDGEARERDEIRHDRRKERQHDRN 368
ERK ++E+EK + + +K R+R G K EK+ + RER + R +RKER+ R
Sbjct: 35 ERKKERREREKRKRE----REKERKRERGKK---EKKKRKKRERGKERERKRKEREKQRK 87
Query: 369 LSRAAPDKRSKLQRNENRD 387
R ++R + + + R+
Sbjct: 88 -ERREKERRKRKKEKKKRE 105
Score = 37.7 bits (86), Expect = 0.027
Identities = 20/92 (21%), Positives = 44/92 (47%), Gaps = 6/92 (6%)
Query: 296 RKAREAVEMRAQVERKMAQKEKEKHEEKLREMAQKARERRAGIKTHVEKEDGEARERDEI 355
R RE + + + ER+ K++ + + K R ++ +ER+ EKE G+ + +
Sbjct: 109 RGRRERKKKKERKERERENKQRRERKRKKRRKKKRRKERKR------EKERGKRERKRKK 162
Query: 356 RHDRRKERQHDRNLSRAAPDKRSKLQRNENRD 387
R +E++ +RN ++ K +R ++
Sbjct: 163 RKKEEREKKRERNRKERKKERERKERRERKKE 194
Score = 36.6 bits (83), Expect = 0.059
Identities = 21/88 (23%), Positives = 50/88 (56%), Gaps = 3/88 (3%)
Query: 299 REAVEMRAQVERKMAQKEKEKHEEKLREMAQKARERRAGIKTHVEKEDGEARERDEIRHD 358
RE+ + + ER+ ++E+EK E+ RE +K +++R + E+E + +ER++ R +
Sbjct: 32 RESERKKERREREKRKREREK--ERKRERGKKEKKKRKKRERGKERER-KRKEREKQRKE 88
Query: 359 RRKERQHDRNLSRAAPDKRSKLQRNENR 386
RR++ + R + +++ + +R +
Sbjct: 89 RREKERRKRKKEKKKRERKQRGRRERKK 116
>gi|116008442 zinc finger CCCH-type containing 13 [Homo sapiens]
Length = 1564
Score = 45.8 bits (107), Expect = 1e-04
Identities = 29/97 (29%), Positives = 50/97 (51%), Gaps = 10/97 (10%)
Query: 295 DRKAREAVEMRAQVERKMAQKEKEKHEEKLREMA---QKARERRAGIKTHVEKEDGEARE 351
D +ARE R + + ++E+E+ E+ +E ++ARER E+E RE
Sbjct: 673 DERARERDRERERDRERERERERERDREREKERELERERARERER------EREKERDRE 726
Query: 352 RDEIR-HDRRKERQHDRNLSRAAPDKRSKLQRNENRD 387
RD R HDR +ER+ +R+ + +R + +R R+
Sbjct: 727 RDRDRDHDRERERERERDREKEREREREERERERERE 763
Score = 43.5 bits (101), Expect = 5e-04
Identities = 51/250 (20%), Positives = 100/250 (40%), Gaps = 33/250 (13%)
Query: 295 DRKAREAVEMRAQVERKMAQKEKEKHEEKLREMAQKARERRAGIKTHVEKEDGEARERDE 354
+R+ + + ER+ ++E+E+ E+ RE ++ RA + + + ++D+
Sbjct: 736 ERERERERDREKEREREREERERERERERERERERERERERARERDKERERQRDWEDKDK 795
Query: 355 IRHDRRKERQ---HDRNLSRAAPDKRSKLQRNENRDISEVIALGVPNPRTSNEVQYDQRL 411
R DRR++R+ DRN R D+R +R N G P+PR S + + +
Sbjct: 796 GRDDRREKREEIREDRN-PRDGHDERKSKKRYRNE--------GSPSPRQSPKRRREH-- 844
Query: 412 FNQSKGMDSGFAGGEDEIYNVYDQAWRGGKDMAQSIYRP--SKNLDKDMYGDDLEARIKT 469
+ + YN D + ++Q + RP S++L +D + R K
Sbjct: 845 ------------SPDSDAYNSGDDKNEKHRLLSQ-VVRPQESRSLSPSHLTEDRQGRWKE 891
Query: 470 NRFVPDKEFSGSDRRQRGREGPVQFEEDPFGLDKFLEEAKQHG----GSKRPSDSSRPKE 525
P+++ S ++ + V + + LE ++ G + D
Sbjct: 892 EDRKPERKESSRRYEEQELKEKVSSVDKQREQTEILESSRMRAQDIIGHHQSEDRETSDR 951
Query: 526 HEHEGKKRRK 535
E KK+ K
Sbjct: 952 AHDENKKKAK 961
Score = 36.2 bits (82), Expect = 0.077
Identities = 63/289 (21%), Positives = 112/289 (38%), Gaps = 32/289 (11%)
Query: 265 DKRLAADGRGLQTVHINENFAKLAEALYIADRK-----AREAVEMRAQVERKMAQKEKEK 319
D R DGR + + +L ++ + D + +R+ E R + + + +
Sbjct: 448 DDREPRDGRDRRDARDTRDRRELRDSRDMRDSREMRDYSRDTKESRDPRDSRSTRDAHDY 507
Query: 320 HEEKLREMAQKA----RERRAGIKTHVEKEDGEARERDEIRHDRRKERQHDR-NLSRA-- 372
+ + R+ +K E R+ + H+ +E R+E R++ R E ++DR SR
Sbjct: 508 RDREGRDTHRKEDTYPEESRSYGRNHLREESSRTEIRNESRNESRSEIRNDRMGRSRGRV 567
Query: 373 --APDKRSKLQRNENRDISEVIALGVPNPRTSNEV----QYDQRLFNQSKGMDSGFAGGE 426
P+K S+ R D + + T + +Y +R N+ + DS F
Sbjct: 568 PELPEKGSRGSRGSQIDSHSSNSNYHDSWETRSSYPERDRYPER-DNRDQARDSSFERRH 626
Query: 427 DEIYNVYDQAWRGGKDMAQSIYRPSKNLDKDMYGDDLEARIKTNRFVPDKEFSGSDRR-Q 485
E R +D + RPS + D+LE + D+ DRR +
Sbjct: 627 GE---------RDRRDNRERDQRPSSPIRHQGRNDELERDERREERRVDRV---DDRRDE 674
Query: 486 RGREGPVQFEEDPFGLDKFLEEAKQHGGSKRPSDSSRPKEHEHEGKKRR 534
R RE + E D + E + +R + R +E E E +K R
Sbjct: 675 RARERDRERERDRERERERERERDREREKERELERERAREREREREKER 723
Score = 32.7 bits (73), Expect = 0.86
Identities = 22/94 (23%), Positives = 42/94 (44%), Gaps = 2/94 (2%)
Query: 295 DRKAREAVEMRAQVERKMAQKEKEKHEEKLREMAQKARERRAGIKTHVEKEDGEARERDE 354
+R R + +R Q +++ E+ EE+ + R+ RA + + D E E
Sbjct: 636 ERDQRPSSPIRHQGRNDELERD-ERREERRVDRVDDRRDERARERDRERERDRERERERE 694
Query: 355 IRHDRRKERQHDRNLSRAAPDKRSK-LQRNENRD 387
DR +E++ + RA +R + +R+ RD
Sbjct: 695 RERDREREKERELERERAREREREREKERDRERD 728
Score = 31.2 bits (69), Expect = 2.5
Identities = 25/94 (26%), Positives = 40/94 (42%), Gaps = 7/94 (7%)
Query: 295 DRKAREAVEMRAQVERKMAQKEKEKHEEKLREMAQKARERRAGIKTHVEKEDGEARERDE 354
D + E R R +E+++ E+ RE RER + E+E ER+
Sbjct: 657 DERREERRVDRVDDRRDERARERDRERERDRE-----RERERERERDREREKERELERER 711
Query: 355 IR-HDRRKERQHDRNLSRAAPDKRSKLQRNENRD 387
R +R +E++ DR R R + +R RD
Sbjct: 712 AREREREREKERDRERDRDRDHDRER-ERERERD 744
Score = 30.8 bits (68), Expect = 3.3
Identities = 22/81 (27%), Positives = 34/81 (41%), Gaps = 3/81 (3%)
Query: 311 KMAQKEKEKHEEKLREMAQKARERRAGIKTHVEKEDGEARERDEIRHDRRKERQHDRNLS 370
+ +Q +HE RE + R+R + E E ++ RD R DR DR +
Sbjct: 405 RTSQSHDRRHER--REDTRGKRDREKDSREEREYEQDQSSSRDH-RDDREPRDGRDRRDA 461
Query: 371 RAAPDKRSKLQRNENRDISEV 391
R D+R + RD E+
Sbjct: 462 RDTRDRRELRDSRDMRDSREM 482
Score = 29.6 bits (65), Expect = 7.2
Identities = 21/84 (25%), Positives = 39/84 (46%), Gaps = 9/84 (10%)
Query: 315 KEKEKHE-EKLREMAQKARERRAGIKTHVEKEDGEARERDEIRHDRRKERQH-------D 366
+EK +H+ E+ + + ERR + ++E ++RE E D+ R H D
Sbjct: 396 REKGRHDHERTSQSHDRRHERREDTRGKRDREK-DSREEREYEQDQSSSRDHRDDREPRD 454
Query: 367 RNLSRAAPDKRSKLQRNENRDISE 390
R A D R + + ++RD+ +
Sbjct: 455 GRDRRDARDTRDRRELRDSRDMRD 478
>gi|239745079 PREDICTED: Putative golgin subfamily A member 6-like
protein 6 [Homo sapiens]
Length = 724
Score = 45.4 bits (106), Expect = 1e-04
Identities = 52/263 (19%), Positives = 112/263 (42%), Gaps = 40/263 (15%)
Query: 282 ENFAKLAEALYIADRKAREAVEMRAQVERKMAQKEKEKHE-EKLREMAQKARERRAGIKT 340
E + E ++ + K R EM + E K+ + E++ HE EK+RE +K R+ I+
Sbjct: 410 EKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEK-RQEEEKIRE 468
Query: 341 HVEKEDGEA---RERDEIRHDRRKERQHDRNLSRAAP--DKRSKLQRNENRDISEVIALG 395
++++ EA R+ ++IR K R+ + + R ++ K++ E R E +
Sbjct: 469 QEKRQEQEAKMWRQEEKIREQEEKIREQEEKMWRQEEKIHEQEKIREEEKRQEQEEMW-- 526
Query: 396 VPNPRTSNEVQYDQRLFNQSKGMDSGFAGGEDEIYNVYDQAWRGGKDMAQSIYRPSKNLD 455
R +++ + ++ Q + + E++I ++ WR + M
Sbjct: 527 ----RQEEKIREQEEIWRQKEKIHE----QEEKIRKQEEKMWRQEEKM------------ 566
Query: 456 KDMYGDDLEARIKTNRFVPDKEFSGSDRRQRGREGPVQFEEDPFGLDKFL--EEAKQHGG 513
D E +I+ +++ + + R +E ++ +E+ + + E+ ++ G
Sbjct: 567 -----HDQEEKIREQ----EEKVWRQEEKIREQEEKIREQEEKIREQEEMTQEQEEKMGE 617
Query: 514 SKRPSDSSRPKEHEHEGKKRRKE 536
+ K E E K RR+E
Sbjct: 618 QEEKMCEQEEKMQEQEEKMRRQE 640
Score = 38.5 bits (88), Expect = 0.016
Identities = 26/114 (22%), Positives = 58/114 (50%), Gaps = 9/114 (7%)
Query: 282 ENFAKLAEALYIADRKAREAVEMRAQVERKMAQKEKE--KHEEKLREMAQKARERRAGIK 339
E + E + + K RE EM + E KM ++E++ + EEK++E +K R + I+
Sbjct: 585 EKIREQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEEKMRRQEEKIR 644
Query: 340 THVEK---EDGEARERDEIRHDRRKE--RQHDR--NLSRAAPDKRSKLQRNENR 386
+K ++ + RE++E+ ++ ++ Q ++ ++ K++R E +
Sbjct: 645 EQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEK 698
Score = 36.6 bits (83), Expect = 0.059
Identities = 28/117 (23%), Positives = 56/117 (47%), Gaps = 8/117 (6%)
Query: 282 ENFAKLAEALYIADRKAREAVE-MRAQVERKMAQKEK-EKHEEKLREMAQKARERRAGIK 339
E K E ++ + K + E +R Q E+ Q+EK + EEK+RE +K RE+ +
Sbjct: 550 EKIRKQEEKMWRQEEKMHDQEEKIREQEEKVWRQEEKIREQEEKIREQEEKIREQEEMTQ 609
Query: 340 THVEK----EDGEARERDEIRHDRRKERQHDRNLSRAAPDKRSKLQRNENRDISEVI 392
EK E+ + ++++ K R+ + + +K+ + Q + R+ E++
Sbjct: 610 EQEEKMGEQEEKMCEQEEKMQEQEEKMRRQEEKIRE--QEKKIREQEEKIREQEEMM 664
Score = 32.3 bits (72), Expect = 1.1
Identities = 18/80 (22%), Positives = 41/80 (51%), Gaps = 5/80 (6%)
Query: 295 DRKAREAVEMRAQVERKMAQKEK-EKHEEKLREMAQKARERRAGIKTHVEK----EDGEA 349
++ + +M+ Q E+ Q+EK + E+K+RE +K RE+ ++ EK E+
Sbjct: 620 EKMCEQEEKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMC 679
Query: 350 RERDEIRHDRRKERQHDRNL 369
+ ++++ K R+ + +
Sbjct: 680 EQEEKMQEQEEKMRRQEEKM 699
Score = 30.8 bits (68), Expect = 3.3
Identities = 37/146 (25%), Positives = 65/146 (44%), Gaps = 19/146 (13%)
Query: 264 LDKRLAADGRGLQT-VHINENFAKL----AEALYIADRKAREAVEMRAQVERKMAQKEKE 318
L K L + LQ V NE + +L E ++ + K +E E + E K+ ++E++
Sbjct: 331 LGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEK 390
Query: 319 --KHEEKLRE----MAQKARERRAGIKTHVEKEDGEARERDEIRHDRRK-----ERQHDR 367
+ EEK+R M +K + R + EKE+ R+ + + K E+ H++
Sbjct: 391 IREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQ 450
Query: 368 NLSRAAPDKR---SKLQRNENRDISE 390
R +KR K++ E R E
Sbjct: 451 EKIREQEEKRQEEEKIREQEKRQEQE 476
>gi|41152097 DNA segment on chromosome X and Y (unique) 155
expressed sequence isoform 1 [Homo sapiens]
Length = 695
Score = 45.4 bits (106), Expect = 1e-04
Identities = 29/103 (28%), Positives = 56/103 (54%), Gaps = 6/103 (5%)
Query: 292 YIADRKAREAVEMRAQVERKMAQKEKEKHEEKLREMAQKARERRAGIKTHVEKEDGEARE 351
+++D ++ R +++ Q+E++K EK E Q+A ER+ + +E+ + E +
Sbjct: 262 HLSDASIKKRQLERQKLQELEQQREEQKRREKEAEERQRAEERK---QKELEELERERKR 318
Query: 352 RDEIRHDRRKERQHDRNLSRAAPDKRSKLQRNENRDISEVIAL 394
+++R +R+++Q DR L R K KLQ E + + E I L
Sbjct: 319 EEKLR--KREQKQRDREL-RRNQKKLEKLQAEEQKQLQEKIKL 358
Score = 34.3 bits (77), Expect = 0.29
Identities = 26/81 (32%), Positives = 42/81 (51%), Gaps = 7/81 (8%)
Query: 296 RKAREAVEMRAQVERKMAQKE----KEKHEEKLREMAQKARE---RRAGIKTHVEKEDGE 348
R+ +EA E + ERK + E + K EEKLR+ QK R+ RR K + + +
Sbjct: 290 RREKEAEERQRAEERKQKELEELERERKREEKLRKREQKQRDRELRRNQKKLEKLQAEEQ 349
Query: 349 ARERDEIRHDRRKERQHDRNL 369
+ +++I+ + RK RNL
Sbjct: 350 KQLQEKIKLEERKLLLAQRNL 370
Score = 34.3 bits (77), Expect = 0.29
Identities = 24/97 (24%), Positives = 38/97 (39%), Gaps = 4/97 (4%)
Query: 293 IADRKAREAVEMRAQVERKMAQKEKEKHEEKLREMAQKARERRAGIKTHVEKEDGEARER 352
+ADR RE R R+ + KE+ K + RR+ H R
Sbjct: 595 LADRHKRERSRARRASSREDGRPRKERRPHKKHAYKDDSPRRRSTSPDHTRSR----RSH 650
Query: 353 DEIRHDRRKERQHDRNLSRAAPDKRSKLQRNENRDIS 389
+ RH R + R+ + SR R + +R+ +R S
Sbjct: 651 SKDRHRRERSRERRGSASRKHSRHRRRSERSRSRSPS 687
>gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-like
[Homo sapiens]
Length = 899
Score = 44.7 bits (104), Expect = 2e-04
Identities = 40/209 (19%), Positives = 92/209 (44%), Gaps = 18/209 (8%)
Query: 299 REAVEMRAQV-ERKMAQKEKEKHEEKLREMAQKARERRAGIKTHVEK----EDGEARERD 353
+E +E + Q E+K +EK + EE +RE +K RE ++ EK E+ + +
Sbjct: 689 QEKMEKKTQEQEKKTWDQEKMREEESMREREKKMREEEEMMREQEEKMQEQEEKMQEQEE 748
Query: 354 EIRHDRRKERQHDRNL--SRAAPDKRSKLQRNENRDISEVIALGVPNPRTSNEVQYDQRL 411
E+ K + + + + P+++ KL +E E I R E Q
Sbjct: 749 EMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKIWEQEEKMRDQEEKMRGQE- 807
Query: 412 FNQSKGMDSGFAGGEDEIYNVYDQAWRGGKDM---AQSIYRPSKNLDKDMYGDDLEARIK 468
+ +G + G E++++ ++ W + M + ++ + +++ M G + + R +
Sbjct: 808 -EKMRGQEEKMRGQEEKMWGQEEKMWGQEEKMWGQEEKMWGQEEKMEEKMQGQEEKMREQ 866
Query: 469 TNRFVPDKEFSGSDRRQRGREGPVQFEED 497
+++ G + + R +E ++ +E+
Sbjct: 867 ------EEKMRGQEEKMREQEEKMRGQEE 889
Score = 44.3 bits (103), Expect = 3e-04
Identities = 44/245 (17%), Positives = 104/245 (42%), Gaps = 43/245 (17%)
Query: 296 RKAREAVEMRAQVERKMAQKEKEKHEEKLREMAQKARERRAGI---KTHVEKEDGEARER 352
RK A + QV+ Q+E + EE+LRE +K R++ + + + +++G+ RE+
Sbjct: 253 RKLERAKFLLPQVQTNTLQEEMWRQEEELREQEKKIRKQEEKMWRQEERLREQEGKMREQ 312
Query: 353 DE-IRHDRRKERQHDRNLSRAAPDKRSKLQRNENRDISEVIALGVPNPRTSNEVQYDQRL 411
+E + ++ R+ ++ L + R + + E + + + ++++
Sbjct: 313 EEKMWRQEKRLREQEKELREQEKELREQKELREQEEQMQ---------------EQEEKM 357
Query: 412 FNQSKGMDSGFAGGEDEIYNVYDQAWRGGKDMAQSIYRPSKNLDKDMYGDDLEARIKTNR 471
+ Q + M E++++ ++ W K M + + ++ ++ M+ D R
Sbjct: 358 WEQEEKMRE----QEEKMWRQEERLWEQEKQMREQ-EQKMRDQEERMWEQDERLR----- 407
Query: 472 FVPDKEFSGSDRRQRGREGPVQFEEDPFGLDKFLEEAKQHGGSKRPSDSSRPKEHEHEGK 531
++ +R RE +E+ ++K EE K K+ D + E +
Sbjct: 408 ----------EKEERMREQEKMWEQ----VEKMREEKKMQEQEKKTRDQEEKMQEEERIR 453
Query: 532 KRRKE 536
+R K+
Sbjct: 454 EREKK 458
Score = 42.4 bits (98), Expect = 0.001
Identities = 47/263 (17%), Positives = 107/263 (40%), Gaps = 35/263 (13%)
Query: 289 EALYIADRKAREAVEMRAQVERKMAQKEKEKHEEKLREMAQKARERRAGIKTHVEKEDGE 348
E ++ D + RE E + E+ Q EK + E+K++E +K R++ ++ + E
Sbjct: 397 ERMWEQDERLREKEERMREQEKMWEQVEKMREEKKMQEQEKKTRDQEEKMQEEERIRERE 456
Query: 349 ARERDE---IRHDRRKERQHDRNL---------SRAAPDKRSKLQRNENRDISEVIALGV 396
+ R+E +R K ++ + N+ + P+++ KL E E
Sbjct: 457 KKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIW-- 514
Query: 397 PNPRTSNEVQYDQRLFNQSKGMDSGFAGGEDEIYNVYDQAWRGG---KDMAQSIYRPSKN 453
+++ + ++ Q K M ++++ DQ W +D Q ++ +
Sbjct: 515 ---EQEEKIRDQEEMWGQEKKM-----WRQEKMREQEDQMWEQEEKMRDQEQKMWDQEER 566
Query: 454 LDKDMYGDDLEARIKTNRFVPDKEFSGSDRRQRGREGPVQFEEDPFGLDKFLEEAKQHGG 513
++K + + + + +E + R R RE ++ EE+ + + EE Q
Sbjct: 567 MEK-------KTQEQEKKTWDQEEKMREEERMREREKKMREEEE---MMREQEEKMQEQE 616
Query: 514 SKRPSDSSRPKEHEHEGKKRRKE 536
K + E E + +++ ++
Sbjct: 617 EKMQEQEEKMWEQEEKMQEQEEK 639
Score = 37.0 bits (84), Expect = 0.045
Identities = 28/111 (25%), Positives = 52/111 (46%), Gaps = 9/111 (8%)
Query: 282 ENFAKLAEALYIADRKAREAVE-MRAQVERKMAQ-------KEKEKHEEKLREMAQKARE 333
E + E L+ +++ RE + MR Q ER Q +E+ + +EK+ E +K RE
Sbjct: 369 EKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQVEKMRE 428
Query: 334 RRAGIKTHVEKEDGEARERDEIR-HDRRKERQHDRNLSRAAPDKRSKLQRN 383
+ + + D E + ++E R +R K+ + + R +K K + N
Sbjct: 429 EKKMQEQEKKTRDQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEEN 479
Score = 33.5 bits (75), Expect = 0.50
Identities = 23/99 (23%), Positives = 46/99 (46%), Gaps = 1/99 (1%)
Query: 289 EALYIADRKAREAV-EMRAQVERKMAQKEKEKHEEKLREMAQKARERRAGIKTHVEKEDG 347
E ++ +++ RE E+R Q + QKE + EE+++E +K E+ ++ EK
Sbjct: 314 EKMWRQEKRLREQEKELREQEKELREQKELREQEEQMQEQEEKMWEQEEKMREQEEKMWR 373
Query: 348 EARERDEIRHDRRKERQHDRNLSRAAPDKRSKLQRNENR 386
+ E R++ Q R+ ++ +L+ E R
Sbjct: 374 QEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEER 412
Score = 33.1 bits (74), Expect = 0.66
Identities = 52/267 (19%), Positives = 102/267 (38%), Gaps = 28/267 (10%)
Query: 282 ENFAKLAEALYIADRKAREAVEMRAQVERKMAQKEKEK------HEEKLREMAQKARERR 335
E + E ++ + K E E + +R QKEK +EK++E +K E+
Sbjct: 631 EKMQEQEEKMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKMQEQEEKIWEQE 690
Query: 336 AGIKTHVEKE----DGEARERDEIRHDRRKERQHDRNLSRAAPDKRSKLQRNENRDISEV 391
K E+E D E +E +R K+ + + + R +K + + E+
Sbjct: 691 KMEKKTQEQEKKTWDQEKMREEESMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEEM 750
Query: 392 IALGVPNPRTSNEVQYDQRLFNQSKGMDSGFAGGEDEIYNVYDQAWRGGKDMAQSIYRPS 451
++ QRL Q + + E E ++ W + M
Sbjct: 751 WEQEEKMWEQEEKMWEQQRLPEQKEKL------WEHEKMQEQEKIWEQEEKM-------- 796
Query: 452 KNLDKDMYGDDLEARIKTNRFVPDKE-FSGSDRRQRGREGPVQFEEDP-FGLDKFLEEAK 509
++ ++ M G + + R + + +E G + + G+E + +E+ +G ++ +EE
Sbjct: 797 RDQEEKMRGQEEKMRGQEEKMRGQEEKMWGQEEKMWGQEEKMWGQEEKMWGQEEKMEEKM 856
Query: 510 QHGGSKRPSDSSRPKEHEHEGKKRRKE 536
Q G + K E K R +E
Sbjct: 857 Q--GQEEKMREQEEKMRGQEEKMREQE 881
Score = 32.3 bits (72), Expect = 1.1
Identities = 45/250 (18%), Positives = 106/250 (42%), Gaps = 32/250 (12%)
Query: 295 DRKAREAVEMRAQVERKMAQKEKE--KHEEKLREMAQKARERRAGIKTHVEK--EDGEAR 350
+R + +MR Q E+KM +E+ + +E+LRE ++ RE+ + VEK E+ + +
Sbjct: 376 ERLWEQEKQMREQ-EQKMRDQEERMWEQDERLREKEERMREQEK-MWEQVEKMREEKKMQ 433
Query: 351 ERDEIRHDRRKERQHDRNLSRAAPDKRSKLQRNENRDISEVIALGVPNPRTSNEVQYDQR 410
E+++ D+ ++ Q + + +K+ + + R+ E + N E ++ Q+
Sbjct: 434 EQEKKTRDQEEKMQEEERIRER--EKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQ 491
Query: 411 LFNQSKGMDSGFAGGEDEIYNVYDQAWRGGK--DMAQSIYRPSKNL--DKDMYGDDLEAR 466
+ K ++ W K + + I+ + + ++M+G + +
Sbjct: 492 RLPEQK-----------------EKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMW 534
Query: 467 IKTNRFVPDKEFSGSDRRQRGREGPVQFEEDPFGLDKFLEEAKQHGGSKRPSDSSRPKEH 526
+ + + + + R +E + +E+ +E K ++ + R +E
Sbjct: 535 RQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMEKKTQEQEKKTWDQEEKMREEERMRER 594
Query: 527 EHEGKKRRKE 536
E KK R+E
Sbjct: 595 E---KKMREE 601
Score = 30.8 bits (68), Expect = 3.3
Identities = 27/112 (24%), Positives = 54/112 (48%), Gaps = 11/112 (9%)
Query: 286 KLAEALYIADRKAREAV-EMRAQVERKMAQKEKEKHEEK-LREMAQKARERRAGIKTHVE 343
K E ++ + + RE +MR Q E+ Q+++ + +EK LRE ++ RE+ K E
Sbjct: 290 KQEEKMWRQEERLREQEGKMREQEEKMWRQEKRLREQEKELREQEKELREQ----KELRE 345
Query: 344 KEDGEARERDEIRHDRRKERQHDRNLSRA-----APDKRSKLQRNENRDISE 390
+E+ + +++ K R+ + + R +K+ + Q + RD E
Sbjct: 346 QEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEE 397
Score = 29.6 bits (65), Expect = 7.2
Identities = 41/266 (15%), Positives = 101/266 (37%), Gaps = 16/266 (6%)
Query: 282 ENFAKLAEALYIADRKAREAVEMRAQVERKMAQKEKEKHEEKLREMAQKARERRAGIKTH 341
E + E + + E E Q +R QKEK +EK++E +K E+ I+
Sbjct: 464 ETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQ 523
Query: 342 VE---------KEDGEARERDEIRHDRRKERQHDRNL--SRAAPDKRSKLQRNENRDISE 390
E +++ + D++ K R ++ + +K+++ Q + D E
Sbjct: 524 EEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMEKKTQEQEKKTWDQEE 583
Query: 391 VIALGVPNPRTSNEVQYDQRLFNQSKGMDSGFAGGEDEIYNVYDQAWRGGKDMAQSIYRP 450
+ +++ ++ + + + E+++ ++ W + M + +
Sbjct: 584 KMREEERMREREKKMREEEEMMRE---QEEKMQEQEEKMQEQEEKMWEQEEKMQEQEEKM 640
Query: 451 SKNLDKDMYGDDLEARIKTNRFVPDKEFSGSDRRQRGREGPVQFEEDPFGLDKFLEEAKQ 510
+ +K + E + R KE + + +E + EE + +K ++ ++
Sbjct: 641 WEQEEK--MWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKMQEQEEKIWEQEKMEKKTQE 698
Query: 511 HGGSKRPSDSSRPKEHEHEGKKRRKE 536
+ R +E E +K+ +E
Sbjct: 699 QEKKTWDQEKMREEESMREREKKMRE 724
>gi|239747134 PREDICTED: hypothetical protein XP_002343921 [Homo
sapiens]
Length = 600
Score = 44.3 bits (103), Expect = 3e-04
Identities = 55/242 (22%), Positives = 95/242 (39%), Gaps = 12/242 (4%)
Query: 296 RKAREAVEMRAQVERKMAQKEKEKHEEKLREMAQKARERRAGIKTHVEKEDGEARERDEI 355
+K RE + R + + Q+EKE E + RER +T E++ RERD
Sbjct: 176 QKEREREKNRQERRERERQREKENKTEDRHSERGRERERERETETETERKRQTDRERDRQ 235
Query: 356 RH-DRRKERQHDRNLSRAAPDKRSK-LQRNENRDISEVIALGVPNPRTSNEVQYDQRLFN 413
R +R +E+Q +R + +R K +R +RD + E Q D++
Sbjct: 236 RKTEREREKQAERERASERETERDKERERERDRDRDR------DRRQKERERQTDRKRQR 289
Query: 414 QSKGMDSGFAGGEDEIYNVYDQAWRGGKDMAQSIYRPSKNLDKDMYGDDLEARIKTNRFV 473
+++ E + ++ ++ + R + + + E K R
Sbjct: 290 RTERDRETERKRERQRERERERERNRKRERERERERERERQRETERDREKERERKRKR-- 347
Query: 474 PDKEFSGSDRRQRGREGPVQFE-EDPFGLDKFLEEAKQHGGSKRPSDSSRPKEHEHEGKK 532
E RQ GREG Q E E ++ + A++ +R D R KE E + +K
Sbjct: 348 -QTEMDRERNRQTGREGRRQAERERERERERDRQSAREREERERDRDRDRQKERERQTEK 406
Query: 533 RR 534
R
Sbjct: 407 DR 408
Score = 40.8 bits (94), Expect = 0.003
Identities = 24/94 (25%), Positives = 46/94 (48%), Gaps = 3/94 (3%)
Query: 295 DRKAREAVEMRAQVERKMAQKEKEKHEEKLREMAQKARERRAGIKTHVEKEDGEARERDE 354
+R+ E + Q +R+ ++ K + E + + ++A ER + E+E R+RD
Sbjct: 215 ERETETETERKRQTDRERDRQRKTEREREKQAERERASERET--ERDKERERERDRDRDR 272
Query: 355 IRHDRRKERQHDRNLSRAAP-DKRSKLQRNENRD 387
R + +ERQ DR R D+ ++ +R R+
Sbjct: 273 DRRQKERERQTDRKRQRRTERDRETERKRERQRE 306
Score = 40.8 bits (94), Expect = 0.003
Identities = 28/98 (28%), Positives = 44/98 (44%), Gaps = 2/98 (2%)
Query: 295 DRKAREAVEMRAQVERKMAQKEKEKHEEKLRE-MAQKARERRAGIKTHVEKEDGEARERD 353
DR R+ R ++ + E+++ E+ RE ++ RER K E+E RER
Sbjct: 271 DRDRRQKERERQTDRKRQRRTERDRETERKRERQRERERERERNRKRERERERERERERQ 330
Query: 354 -EIRHDRRKERQHDRNLSRAAPDKRSKLQRNENRDISE 390
E DR KER+ R +R++ E R +E
Sbjct: 331 RETERDREKERERKRKRQTEMDRERNRQTGREGRRQAE 368
Score = 40.4 bits (93), Expect = 0.004
Identities = 32/92 (34%), Positives = 47/92 (51%), Gaps = 6/92 (6%)
Query: 295 DRKAREAVEMRAQVERKMAQKEKEKHEEKLRE---MAQKARERRAGIKTHVEKEDGEARE 351
DR++ E R + + QKE+E+ EK R+ +K RER ++ +E G RE
Sbjct: 378 DRQSAREREERERDRDRDRQKERERQTEKDRDGQRETEKQREREKDRESERGRERGRERE 437
Query: 352 RDEIRHDRRKERQHDRNLSRAAPDKRSKLQRN 383
+ + R +R +ERQ DR R KRS L N
Sbjct: 438 KQKGR-ERDRERQTDRQAGRQR--KRSTLYVN 466
Score = 38.9 bits (89), Expect = 0.012
Identities = 30/105 (28%), Positives = 51/105 (48%), Gaps = 13/105 (12%)
Query: 295 DRKAREAVEMRAQVERKMA---------QKEKEKHEEKLREMAQKARERRAGIKTH--VE 343
DR+ + E Q ER+ A ++E+E+ ++ R+ QK RER+ K E
Sbjct: 233 DRQRKTEREREKQAERERASERETERDKERERERDRDRDRDRRQKERERQTDRKRQRRTE 292
Query: 344 KEDGEARERDEIRHDRRKERQHDRNLSRAAPDKRSK-LQRNENRD 387
++ R+R+ R +R +ER+ +R R +R + QR RD
Sbjct: 293 RDRETERKRERQR-ERERERERNRKRERERERERERERQRETERD 336
Score = 38.5 bits (88), Expect = 0.016
Identities = 28/98 (28%), Positives = 45/98 (45%), Gaps = 10/98 (10%)
Query: 295 DRKAREAVEMRAQVERKMAQKEKEKHE-EKLREMAQKARERRAGIKTHVEKEDGEARERD 353
DR+ + E Q ER+ + +E+ E E+ RE K +R + E G RER+
Sbjct: 164 DRERQRQTERNRQKEREREKNRQERRERERQREKENKTEDRHS--------ERGRERERE 215
Query: 354 -EIRHDRRKERQHDRNLSRAAPDKRSKLQRNENRDISE 390
E + ++RQ DR R +R + ++ E SE
Sbjct: 216 RETETETERKRQTDRERDRQRKTEREREKQAERERASE 253
Score = 38.1 bits (87), Expect = 0.020
Identities = 31/93 (33%), Positives = 46/93 (49%), Gaps = 7/93 (7%)
Query: 299 REAVEMRAQVERKMAQKEKEKHEEKLREMAQKARER---RAGIKTHVEKEDGEARERDEI 355
RE R + + +E+++ EK R QK RER R G + + DG+ RER+
Sbjct: 95 RERQRDREKERERQTDRERDRQREKERNR-QKERERETEREGERGRDRQTDGQ-RERERQ 152
Query: 356 RH-DRRKERQHDRNLSRAAPDKRSK-LQRNENR 386
R ++ +ERQ DR R R K +R +NR
Sbjct: 153 RDAEKERERQTDRERQRQTERNRQKEREREKNR 185
Score = 38.1 bits (87), Expect = 0.020
Identities = 26/97 (26%), Positives = 47/97 (48%), Gaps = 8/97 (8%)
Query: 296 RKAREAVEMRAQVERKMAQKEKEKHEEKLREMA---QKARERRAGI--KTHVEKEDGEAR 350
++ RE R + ++ ++++EK E+ R+ + R R+ G + E+E R
Sbjct: 316 KRERERERERERERQRETERDREKERERKRKRQTEMDRERNRQTGREGRRQAERERERER 375
Query: 351 ERDEIRHDRRKERQHDRNLSRAAPDKRSKLQRNENRD 387
ERD R+ER+ DR+ R K + Q ++RD
Sbjct: 376 ERDRQSAREREERERDRDRDR---QKERERQTEKDRD 409
Score = 37.7 bits (86), Expect = 0.027
Identities = 56/263 (21%), Positives = 100/263 (38%), Gaps = 35/263 (13%)
Query: 296 RKAREAVEMRAQVERKMAQKEKEKHEEKLREM---------------AQKARERRAGIKT 340
++ RE R + Q+EKE++ +K RE Q+ RER+ +
Sbjct: 98 QRDREKERERQTDRERDRQREKERNRQKERERETEREGERGRDRQTDGQRERERQRDAEK 157
Query: 341 HVEKEDGEARERDEIRHDRRKERQHDRNLSRAAPDKRSKLQRNENRDISEVIALGVPNPR 400
E++ R+R R+ R+KER+ ++N +R + + N+ D R
Sbjct: 158 ERERQTDRERQRQTERN-RQKEREREKNRQERRERERQREKENKTEDRHSERGRERERER 216
Query: 401 -----TSNEVQYDQRLFNQSKGMDSGFAGGEDEIYNVYDQAWRGGKDMAQSIYRPSKNLD 455
T + Q D+ Q K E E ++ K+ + ++ D
Sbjct: 217 ETETETERKRQTDRERDRQRKTEREREKQAERE--RASERETERDKERER---ERDRDRD 271
Query: 456 KDMYGDDLEA---RIKTNRFVPDKEFSGSDRRQRGREGPVQFEEDPFGLDKFLEEAKQHG 512
+D + E R + R D+E RQR RE + K E ++
Sbjct: 272 RDRRQKERERQTDRKRQRRTERDRETERKRERQRERERERERNR------KRERERERER 325
Query: 513 GSKRPSDSSRPKEHEHEGKKRRK 535
+R ++ R +E E E K++R+
Sbjct: 326 ERERQRETERDREKERERKRKRQ 348
Score = 37.4 bits (85), Expect = 0.035
Identities = 32/117 (27%), Positives = 55/117 (47%), Gaps = 5/117 (4%)
Query: 296 RKAREAVEMRAQVERKMAQKEKEKHEEKLREMAQKARERRAGIKTHVEKEDGEARERDEI 355
R+A E + +R+ A++ +E+ ++ R+ QK RER+ ++E + RER++
Sbjct: 365 RQAERERERERERDRQSAREREERERDRDRDR-QKERERQTEKDRDGQRETEKQREREKD 423
Query: 356 RH-DRRKERQHDRNLSRAAP-DKRSKLQRNENRDISEVIALGVPNPRT--SNEVQYD 408
R +R +ER +R + D+ + R R P PRT S VQ D
Sbjct: 424 RESERGRERGREREKQKGRERDRERQTDRQAGRQRKRSTLYVNPPPRTARSGVVQSD 480
Score = 37.0 bits (84), Expect = 0.045
Identities = 29/84 (34%), Positives = 39/84 (46%), Gaps = 7/84 (8%)
Query: 310 RKMAQKEKEKHEEKLREMAQKARERRAGIKTHVEKEDGEARER--DEIRH---DRRKERQ 364
R + Q K+ + QK RERR K E+E RER ++ RH DR +ERQ
Sbjct: 40 RGLGQAHKDADGDDRERNRQKERERRRE-KRQTERETDRKRERRREKDRHRKRDRHRERQ 98
Query: 365 HDRNLSR-AAPDKRSKLQRNENRD 387
DR R D+ QR + R+
Sbjct: 99 RDREKERERQTDRERDRQREKERN 122
Score = 34.7 bits (78), Expect = 0.23
Identities = 21/77 (27%), Positives = 38/77 (49%), Gaps = 9/77 (11%)
Query: 314 QKEKEKHEEKLREMAQ------KARERRAGIKTHVEKEDGEARERDEIRHDRRKERQHDR 367
++ ++K E+ RE Q + RERR H +++ R+RD ++ +ERQ DR
Sbjct: 55 ERNRQKERERRREKRQTERETDRKRERRREKDRHRKRDRHRERQRD---REKERERQTDR 111
Query: 368 NLSRAAPDKRSKLQRNE 384
R +R++ + E
Sbjct: 112 ERDRQREKERNRQKERE 128
Score = 34.3 bits (77), Expect = 0.29
Identities = 23/93 (24%), Positives = 43/93 (46%), Gaps = 2/93 (2%)
Query: 296 RKAREAVEMRAQVERKMAQKEKEKHEEKLREMAQKARERRAGIKTHVEKEDGEARERD-E 354
+K RE + Q ER+ +K + + E+ + RER+ + E++ R+R E
Sbjct: 59 QKERERRREKRQTERETDRKRERRREKDRHRKRDRHRERQRDREKERERQTDRERDRQRE 118
Query: 355 IRHDRRKERQHD-RNLSRAAPDKRSKLQRNENR 386
+R+KER+ + D+++ QR R
Sbjct: 119 KERNRQKERERETEREGERGRDRQTDGQRERER 151
Score = 33.9 bits (76), Expect = 0.38
Identities = 21/90 (23%), Positives = 43/90 (47%), Gaps = 6/90 (6%)
Query: 295 DRKAREAVEMRAQVERKMAQKEKEKHEEKLREMAQKARERRAGIKTHVEKEDGEARERDE 354
DR+ E + E++ ++E ++ E+ RE + + R H E++ +ER E
Sbjct: 53 DRERNRQKERERRREKRQTERETDRKRERRREKDRHRKRDR-----HRERQRDREKER-E 106
Query: 355 IRHDRRKERQHDRNLSRAAPDKRSKLQRNE 384
+ DR ++RQ ++ +R +R + E
Sbjct: 107 RQTDRERDRQREKERNRQKERERETEREGE 136
Score = 33.9 bits (76), Expect = 0.38
Identities = 20/76 (26%), Positives = 37/76 (48%), Gaps = 6/76 (7%)
Query: 315 KEKEKHEEKLREMAQKARERRAGIKTHVEKEDGEARERDEIR---HDRRKERQHDRNLSR 371
+E+ + +E+ R ++ ER K +E R+RD R DR KER+ + R
Sbjct: 54 RERNRQKERERRREKRQTERETDRKRERRREKDRHRKRDRHRERQRDREKERERQTDRER 113
Query: 372 AAPDKRSKLQRNENRD 387
D++ + +RN ++
Sbjct: 114 ---DRQREKERNRQKE 126
Score = 32.7 bits (73), Expect = 0.86
Identities = 29/91 (31%), Positives = 43/91 (47%), Gaps = 21/91 (23%)
Query: 299 REAVEMRAQVERKMAQKEKEKHEEKLREMAQKARERRAGIKTHVEKEDGEARERDEIRHD 358
RE + R+ A++E+E+ E+ R Q ARER E RERD R D
Sbjct: 353 RERNRQTGREGRRQAERERERERERDR---QSARER-------------EERERDRDR-D 395
Query: 359 RRKER----QHDRNLSRAAPDKRSKLQRNEN 385
R+KER + DR+ R +R + + E+
Sbjct: 396 RQKERERQTEKDRDGQRETEKQREREKDRES 426
Score = 32.0 bits (71), Expect = 1.5
Identities = 26/98 (26%), Positives = 48/98 (48%), Gaps = 3/98 (3%)
Query: 295 DRKAREAVEMRAQVERKMAQKEKEKHEEKLRE-MAQKARERRAGIKTHVEKEDGEARERD 353
DRK RE + + ++ +E+++ EK RE + R+R+ + + +KE ER+
Sbjct: 76 DRK-RERRREKDRHRKRDRHRERQRDREKERERQTDRERDRQREKERNRQKERERETERE 134
Query: 354 -EIRHDRRKERQHDRNLSRAAPDKRSKLQRNENRDISE 390
E DR+ + Q +R R A +R + E + +E
Sbjct: 135 GERGRDRQTDGQRERERQRDAEKERERQTDRERQRQTE 172
Score = 30.8 bits (68), Expect = 3.3
Identities = 21/65 (32%), Positives = 32/65 (49%), Gaps = 3/65 (4%)
Query: 325 REMAQKARERRAGIKTHVEKEDGEARERD--EIRHDRRKERQHDRNLSRAAPDKRSKLQR 382
R + RR G+ + DG+ RER+ + R RR++RQ +R R +R K R
Sbjct: 29 RRPGSQESPRRRGLGQAHKDADGDDRERNRQKERERRREKRQTERETDRKRERRREK-DR 87
Query: 383 NENRD 387
+ RD
Sbjct: 88 HRKRD 92
>gi|148746195 trichohyalin [Homo sapiens]
Length = 1943
Score = 43.9 bits (102), Expect = 4e-04
Identities = 54/262 (20%), Positives = 115/262 (43%), Gaps = 20/262 (7%)
Query: 282 ENFAKLAEALYIADRKAREAVEMRAQVERK----MAQKEKEKHEEKLREMAQKARERRAG 337
E + KL E ++ RE R Q ER+ Q+E+E+ +++LR Q RE+
Sbjct: 486 ERWLKLEEEERREQQERREQQLRREQEERREQRLKRQEEEERLQQRLRSEQQLRREQEER 545
Query: 338 IKTHVEKEDGEA--RERDEIRHDRRKERQHDRNLSRAAPDKRSKLQRNENRDISEVIALG 395
+ +++E+ + +ER E R R +E + D+ L R ++ +L+R + + + +
Sbjct: 546 REQLLKREEEKRLEQERREQRLKREQEERRDQLLKREEERRQQRLKREQEERLEQRLKRE 605
Query: 396 VPNPRTSNEVQYDQRLFNQSKGMDSGFAGGEDEIYNVYDQAWRGGKDM-AQSIYRPSKNL 454
R E + +QRL + + ++ +Q R + + + R + L
Sbjct: 606 EVE-RLEQEERREQRLKREEPEEER-----RQQLLKSEEQEERRQQQLRREQQERREQRL 659
Query: 455 DKDMYGDDLEARIKTNRFVPDKEFSGSDRRQRGREGPVQFEEDPFGLDKFLEEAKQHGGS 514
++ + LE R+K +E ++ Q ++ + K+ + + +
Sbjct: 660 KREEEEERLEQRLKREHEEERREQELAEEEQEQARERIKSR-----IPKWQWQLESEADA 714
Query: 515 KRPSDSSRPKEHEHEGKKRRKE 536
++ SRP+ + EG++RR+E
Sbjct: 715 RQSKVYSRPR--KQEGQRRRQE 734
Score = 42.7 bits (99), Expect = 8e-04
Identities = 22/89 (24%), Positives = 52/89 (58%), Gaps = 1/89 (1%)
Query: 303 EMRAQVERKMAQKEKEKHEEKLREMAQKARERRAGIKTHVEKEDGEARERDEIRHDRRKE 362
E + + E+++ ++++ + E++LR Q RE++ + + +E RE++E RH+++ E
Sbjct: 380 EQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQEEERHEQKHE 439
Query: 363 RQ-HDRNLSRAAPDKRSKLQRNENRDISE 390
++ ++ L R ++R L+R E + E
Sbjct: 440 QERREQRLKREQEERRDWLKREEETERHE 468
Score = 40.4 bits (93), Expect = 0.004
Identities = 30/116 (25%), Positives = 57/116 (49%), Gaps = 8/116 (6%)
Query: 281 NENFAKLAEALYIADRKAREAVEMRAQVERKMAQKEKE----KHEEKLREMAQKARERRA 336
+E + E L + + E + R + + ++ Q+E+E K E LR+ +K +E
Sbjct: 206 DEEQLRRRELLELRRKGREEKQQQRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEP 265
Query: 337 GIKTHVEKEDGEAR--ERDEIRHDRRKERQHDRNLSRAAPDKRSKLQRNENRDISE 390
+ +++E+ + R ER E+R +R++E Q + L R +R Q E R+ E
Sbjct: 266 QRQRELQEEEEQLRKLERQELRRERQEEEQQQQRLRREQQLRRK--QEEERREQQE 319
Score = 40.4 bits (93), Expect = 0.004
Identities = 60/284 (21%), Positives = 116/284 (40%), Gaps = 33/284 (11%)
Query: 282 ENFAKLAEALYIADRKAREAVEMRAQV---------ERKMAQKEKEKHEEKLREMAQKAR 332
E + E L +R+ R E+ Q E ++ ++E EK + RE +
Sbjct: 1054 EELQQEEEQLLGEERETRRRQELERQYRKEEELQQEEEQLLREEPEKRRRQERERQCREE 1113
Query: 333 ERRAGIKTHVEKEDGEARERDEIRHDRRKE---RQHDRNLSRAAPDKRSKLQ-----RNE 384
E + + +E+ E R R E+ R+E +Q + L R P+KR + + R E
Sbjct: 1114 EELQQEEEQLLREEREKRRRQELERQYREEEEVQQEEEQLLREEPEKRRRQELERQYREE 1173
Query: 385 ---NRDISEVIALGVPNPRTSNEVQYDQRLFNQSKGMDSGFAGGEDEIYNVYDQAWRGGK 441
++ +++ R E QY + Q + + ED+ ++ Q W K
Sbjct: 1174 EELQQEEEQLLREEQEKRRQERERQYREEEELQRQKRKQRYR-DEDQRSDLKWQ-WEPEK 1231
Query: 442 DMA---QSIYRPSKNLDKDMYGDDLEARIKTNRFVPDKEFSGSDRRQRGREGP---VQFE 495
+ A +Y K + + + +++++ + D + ++++R RE Q
Sbjct: 1232 ENAVRDNKVY--CKGRENEQFRQLEDSQLRDRQSQQDLQHLLGEQQERDREQERRRWQQR 1289
Query: 496 EDPFGLDKFLEEAKQHGGSKRPSDSSRPKE---HEHEGKKRRKE 536
+ F ++ LE +Q +R S K+ E E K+RR+E
Sbjct: 1290 DRHFPEEEQLEREEQKEAKRRDRKSQEEKQLLREEREEKRRRQE 1333
Score = 38.9 bits (89), Expect = 0.012
Identities = 23/90 (25%), Positives = 47/90 (52%), Gaps = 2/90 (2%)
Query: 297 KAREAVEMRAQVERKMAQKEKEKHEEKLREMAQKARERRAGIKTHVEKEDGEARERDEIR 356
+ ++ E R Q E + Q+E+ + +E+ RE Q RE+ + + +E E R ++R
Sbjct: 307 RRKQEEERREQQEERREQQERREQQEERREQ-QLRREQEERREQQLRREQEEERREQQLR 365
Query: 357 HDRRKERQHDRNLSRAAPDKRSKLQRNENR 386
++ +ER+ ++ L R +R + R E +
Sbjct: 366 REQEEERR-EQQLRREQQLRREQQLRREQQ 394
Score = 38.9 bits (89), Expect = 0.012
Identities = 22/93 (23%), Positives = 52/93 (55%), Gaps = 4/93 (4%)
Query: 295 DRKAREAVEMRAQVERKMAQKEKEKH-EEKLREMAQKARERRAGIKTHVEKEDGEARERD 353
DRK RE + ERK ++E++ H +++ R+ Q+ ++ R + ++D + + R+
Sbjct: 1500 DRKFREQELRSQEPERKFLEEEQQLHRQQRQRKFLQEEQQLRRQERGQQRRQDRDRKFRE 1559
Query: 354 EIRHDRRKERQHDRNLSRAAPDKRSKLQRNENR 386
E ++ ++ + ++ LSR D++ +L+ + R
Sbjct: 1560 E---EQLRQEREEQQLSRQERDRKFRLEEQKVR 1589
Score = 37.7 bits (86), Expect = 0.027
Identities = 20/89 (22%), Positives = 44/89 (49%)
Query: 296 RKAREAVEMRAQVERKMAQKEKEKHEEKLREMAQKARERRAGIKTHVEKEDGEARERDEI 355
R RE R Q E + Q+E+ + +++ RE ++ RE++ + +E RE++E
Sbjct: 299 RLRREQQLRRKQEEERREQQEERREQQERREQQEERREQQLRREQEERREQQLRREQEEE 358
Query: 356 RHDRRKERQHDRNLSRAAPDKRSKLQRNE 384
R +++ R+ + + +L+R +
Sbjct: 359 RREQQLRREQEEERREQQLRREQQLRREQ 387
Score = 37.7 bits (86), Expect = 0.027
Identities = 49/242 (20%), Positives = 99/242 (40%), Gaps = 31/242 (12%)
Query: 298 AREAVEMRAQVERKMAQKEKEKHEEKLREMAQKARERRAGIKTHVEKEDGEARERDEIRH 357
A+ A++ + + E+++ Q+E EE+L+ ++ R R+ + + E+E + E +R
Sbjct: 891 AKPALQEQLRKEQQLLQEE----EEELQREEREKRRRQEQERQYREEEQLQQEEEQLLRE 946
Query: 358 DRRKERQHDRNLSRAAPDKRSKLQRNENRDISEVIALGVPNPRTSNEVQYDQRLFNQSKG 417
+R K R+ +R K KLQ+ E + + E P R E + R
Sbjct: 947 EREKRRRQERERQYR---KDKKLQQKEEQLLGE-----EPEKRRRQEREKKYR------- 991
Query: 418 MDSGFAGGEDEIYNVYDQAWRGGKDMAQSIYRPSKNLDKDMYGDDLEARIKTNRFVPDKE 477
E+E+ +Q R ++ + + KD + E ++ R +
Sbjct: 992 -------EEEELQQEEEQLLREEREKRRRQEWERQYRKKDELQQEEEQLLREER--EKRR 1042
Query: 478 FSGSDRRQRGREGPVQFEEDPFGLDKFLEEAKQHGGSKRPSDSSRPKEHE---HEGKKRR 534
+R+ R E Q EE G ++ ++ R + + +E + E +KRR
Sbjct: 1043 LQERERQYREEEELQQEEEQLLGEERETRRRQELERQYRKEEELQQEEEQLLREEPEKRR 1102
Query: 535 KE 536
++
Sbjct: 1103 RQ 1104
Score = 37.0 bits (84), Expect = 0.045
Identities = 22/107 (20%), Positives = 51/107 (47%), Gaps = 2/107 (1%)
Query: 282 ENFAKLAEALYIADRKAREAVEMRAQVERKMAQKEKEKHEEKLREMA--QKARERRAGIK 339
E KL +R+ E + R + E+++ +K++E+ E+ E Q+ RE++ +
Sbjct: 276 EQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQERREQQEERR 335
Query: 340 THVEKEDGEARERDEIRHDRRKERQHDRNLSRAAPDKRSKLQRNENR 386
+ + E R ++R ++ +ER+ + ++R + R E +
Sbjct: 336 EQQLRREQEERREQQLRREQEEERREQQLRREQEEERREQQLRREQQ 382
Score = 36.6 bits (83), Expect = 0.059
Identities = 30/119 (25%), Positives = 54/119 (45%), Gaps = 4/119 (3%)
Query: 299 REAVEMRAQVERKMAQKEKEKHEEKLREMAQKARERRAGIKTHVEKEDGEARERDEIRHD 358
RE R Q R+ Q +E+ EE+ + ++ R + + E+ D RE + RH+
Sbjct: 409 REQQLRREQQLRREQQLRREQEEERHEQKHEQERREQRLKREQEERRDWLKREEETERHE 468
Query: 359 R-RKERQHDRNLSRAAPDKRSKLQRNENRDISEVIALGVPNPRTSNEVQYDQRLFNQSK 416
+ R+++Q R+ ++ KL+ E R+ E R E + +QRL Q +
Sbjct: 469 QERRKQQLKRDQEEERRERWLKLEEEERREQQE---RREQQLRREQEERREQRLKRQEE 524
Score = 35.8 bits (81), Expect = 0.10
Identities = 50/253 (19%), Positives = 100/253 (39%), Gaps = 17/253 (6%)
Query: 296 RKAREAVEMRAQVERKMAQKE---KEKHEEKLREMAQKARERRAGIKTHVEKEDGEARER 352
R+ RE R + +RK ++E +E+ E+ LR + + R ++ H E+ E
Sbjct: 1322 REEREEKRRRQETDRKFREEEQLLQEREEQPLRRQERDRKFREEELR-HQEQGRKFLEEE 1380
Query: 353 DEIRHDRRKERQHDRNLSRAAPDKRSKLQRNENRDISEVIALGVPNPRTSNEVQYDQRLF 412
+R R+ + ++ +L+++ +R E R + +Q++
Sbjct: 1381 QRLRRQERERKFLKEEQQLRCQEREQQLRQDRDRKFREEEQQLSRQERDRKFREEEQQVR 1440
Query: 413 NQSKGMDSGFAGGEDEIYNVYDQAWRGGKDMAQSIYRPSKNLDK-DMYGDDLEARIKTNR 471
Q + + F E ++ + +R + + Q R + L + + LE + R
Sbjct: 1441 RQER--ERKFLEEEQQLRQERHRKFREEEQLLQE--REEQQLHRQERDRKFLEEEQQLRR 1496
Query: 472 FVPDKEFSGSDRRQRGREGPVQFEEDPFGLD----KFLEE----AKQHGGSKRPSDSSRP 523
D++F + R + E EE KFL+E +Q G +R D R
Sbjct: 1497 QERDRKFREQELRSQEPERKFLEEEQQLHRQQRQRKFLQEEQQLRRQERGQQRRQDRDRK 1556
Query: 524 KEHEHEGKKRRKE 536
E + ++ R+E
Sbjct: 1557 FREEEQLRQEREE 1569
Score = 35.4 bits (80), Expect = 0.13
Identities = 56/258 (21%), Positives = 108/258 (41%), Gaps = 28/258 (10%)
Query: 295 DRKAREAVEMRAQVERK---MAQKEKEKHEEKLREMAQKA---RERRAGIKTHVEKEDGE 348
+++ RE R Q ER+ ++E E+HE++ R+ K ERR E+E E
Sbjct: 439 EQERREQRLKREQEERRDWLKREEETERHEQERRKQQLKRDQEEERRERWLKLEEEERRE 498
Query: 349 ARERDEIRHDRRKERQHDRNLSRAAPDKRSKLQ-------RNENRDISEVIALGVPNPRT 401
+ER E + R +E + ++ L R ++R + + R E + E + R
Sbjct: 499 QQERREQQLRREQEERREQRLKRQEEEERLQQRLRSEQQLRREQEERREQLLKREEEKRL 558
Query: 402 SNEVQYDQRLFNQSKGMDSGFAGGEDEIYNVYDQAWRGGKDMAQSIYRPSKNLDKDMYGD 461
E + +QRL + + E+E + R ++ + + + K + +
Sbjct: 559 EQE-RREQRLKREQEERRDQLLKREEE-----RRQQRLKREQEERLEQRLKREEVERLEQ 612
Query: 462 DLEARIKTNRFVPDKEFSGSDRRQRGREGPVQFEEDPFGLDKFLEEAKQHGGSKRPSDSS 521
+ + R P++E RRQ+ + Q E L + +E ++ KR +
Sbjct: 613 EERREQRLKREEPEEE-----RRQQLLKSEEQEERRQQQLRREQQERREQ-RLKREEEEE 666
Query: 522 RPKE---HEHEGKKRRKE 536
R ++ EHE ++R +E
Sbjct: 667 RLEQRLKREHEEERREQE 684
Score = 34.7 bits (78), Expect = 0.23
Identities = 20/85 (23%), Positives = 42/85 (49%), Gaps = 5/85 (5%)
Query: 303 EMRAQVERKMAQKEKEKHEEKLREMAQKARERRAGIKTHVEKEDGEARERDEIRHDRRKE 362
E + Q E Q+E ++ EE+LR++ ++ R + E++ R ++R + +E
Sbjct: 257 EEKLQEEEPQRQRELQEEEEQLRKLERQELRRE---RQEEEQQQQRLRREQQLRRKQEEE 313
Query: 363 RQHDRNLSRAAPDKRSKLQRNENRD 387
R+ + R ++R Q+ E R+
Sbjct: 314 RREQQEERREQQERRE--QQEERRE 336
Score = 34.7 bits (78), Expect = 0.23
Identities = 49/265 (18%), Positives = 109/265 (41%), Gaps = 14/265 (5%)
Query: 286 KLAEALYIADRKAREAVEMRAQVERKMAQKEK---EKHEEKLREMAQKARERRAGIKTHV 342
KL E R+ +E E ++ER+ ++E+ E+ +++LR Q R++ +
Sbjct: 259 KLQEEEPQRQRELQEEEEQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQ 318
Query: 343 E--KEDGEARERDEIRHD----RRKERQHDRNLSRAAPDKR--SKLQRNENRDISEVIAL 394
E +E E RE+ E R + R +E + ++ L R ++R +L+R + + E
Sbjct: 319 EERREQQERREQQEERREQQLRREQEERREQQLRREQEEERREQQLRREQEEERREQQLR 378
Query: 395 GVPNPRTSNEVQYDQRLFNQSKGMDSGFAGGEDEIYNVYDQAWRGGKDMAQSIYRPSKNL 454
R +++ +Q+L + + E ++ Q R +
Sbjct: 379 REQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQEEERHEQKH 438
Query: 455 DKDMYGDDLEARIKTNRFVPDKEFSGSDRRQRGREGPVQFEEDPFGLDKFL---EEAKQH 511
+++ L+ + R +E Q R+ ++ +++ +++L EE ++
Sbjct: 439 EQERREQRLKREQEERRDWLKREEETERHEQERRKQQLKRDQEEERRERWLKLEEEERRE 498
Query: 512 GGSKRPSDSSRPKEHEHEGKKRRKE 536
+R R +E E + +R+E
Sbjct: 499 QQERREQQLRREQEERREQRLKRQE 523
Score = 33.9 bits (76), Expect = 0.38
Identities = 50/246 (20%), Positives = 105/246 (42%), Gaps = 34/246 (13%)
Query: 295 DRKAREAVEMRAQVERKMAQKEKEKHEEKLREMAQKARERRAGIKTHVEKEDGEARERDE 354
+++ R+ E + + ++K+ QKE E+ L E +K R R+ K + E+E+ + E
Sbjct: 949 EKRRRQERERQYRKDKKLQQKE----EQLLGEEPEK-RRRQEREKKYREEEELQQEEEQL 1003
Query: 355 IRHDRRKERQHDRNLSRAAPDKRSKLQRNENRDISEVIALGVPNPRTSNEVQYDQRLFNQ 414
+R +R K R+ + K+ +LQ+ E + + E R +Q +R + +
Sbjct: 1004 LREEREKRRRQEWERQYR---KKDELQQEEEQLLRE--------EREKRRLQERERQYRE 1052
Query: 415 SKGMDSGFAGGEDEIYNVYDQAWRGGKDMAQSIYRPSKNLDKDMYGDDLEARIKTNRFVP 474
+ + E+E ++ R +++ + YR + L ++ + R P
Sbjct: 1053 EEELQQ-----EEEQLLGEERETRRRQELERQ-YRKEEELQQE--------EEQLLREEP 1098
Query: 475 DKEFSGSDRRQRGREGPVQFEEDPFGLDKFLEEAKQHGGSKRPSDSSRPKEHE----HEG 530
+K RQ E +Q EE+ ++ + +Q + + +E E E
Sbjct: 1099 EKRRRQERERQCREEEELQQEEEQLLREEREKRRRQELERQYREEEEVQQEEEQLLREEP 1158
Query: 531 KKRRKE 536
+KRR++
Sbjct: 1159 EKRRRQ 1164
Score = 32.7 bits (73), Expect = 0.86
Identities = 30/115 (26%), Positives = 49/115 (42%), Gaps = 16/115 (13%)
Query: 282 ENFAKLAEALYIADRKAREAVEMRAQVERKMAQKEKEKHEEKLREMAQKAR--ERRAGIK 339
E + E L +R+ R E Q +K +++E E+ LRE +K R ER +
Sbjct: 994 EELQQEEEQLLREEREKRRRQEWERQYRKKDELQQEE--EQLLREEREKRRLQERERQYR 1051
Query: 340 THVEKEDGEARERDEIRHDRRKE------------RQHDRNLSRAAPDKRSKLQR 382
E + E + E R RR++ +Q + L R P+KR + +R
Sbjct: 1052 EEEELQQEEEQLLGEERETRRRQELERQYRKEEELQQEEEQLLREEPEKRRRQER 1106
Score = 32.3 bits (72), Expect = 1.1
Identities = 22/93 (23%), Positives = 48/93 (51%), Gaps = 5/93 (5%)
Query: 296 RKAREAVEMRAQVERKMAQKEKEKHEEKLREMAQKARERRAGIKTHVEKEDGEARERDEI 355
RK E ++R ER+ Q +++ + K RE ++ R+ R + ++ D + RE +++
Sbjct: 1747 RKILEEEQLRP--EREEQQLRRQERDRKFRE-EEQLRQEREEQQLRSQESDRKFREEEQL 1803
Query: 356 RHDRRKE--RQHDRNLSRAAPDKRSKLQRNENR 386
R +R ++ R R+ +++ +L+ E R
Sbjct: 1804 RQEREEQQLRPQQRDGKYRWEEEQLQLEEQEQR 1836
Score = 32.0 bits (71), Expect = 1.5
Identities = 47/252 (18%), Positives = 101/252 (40%), Gaps = 32/252 (12%)
Query: 296 RKAREAVEMRAQVERKMAQKEKEKHEEKLREMAQKARERRAGIKTHVEKEDGEARERDEI 355
R+ + E R Q E++ +E+EK + + ++ RER ++ E+E + RER +
Sbjct: 794 RERQLRAEERQQREQRFLPEEEEKEQRR-----RQRREREKELQFLEEEEQLQRRERAQQ 848
Query: 356 RHDRRKERQHDRNLSRAAPDKRS-----KLQRNENRDISEVIALGVPNPRTSNEVQYDQR 410
+ Q D+ R+ +R +L+ R + A P +++ +Q+
Sbjct: 849 LQEEEDGLQEDQERRRSQEQRRDQKWRWQLEEERKRRRHTLYA----KPALQEQLRKEQQ 904
Query: 411 LFNQSKGMDSGFAGGEDEIYNVYDQAWRGGKDMAQSIYRPSKNL---DKDMYGDDLEARI 467
L + E+E+ + R + Q YR + L ++ + ++ E R
Sbjct: 905 LLQEE----------EEELQREEREKRRRQEQERQ--YREEEQLQQEEEQLLREEREKRR 952
Query: 468 KTNR---FVPDKEFSGSDRRQRGREGPVQFEEDPFGLDKFLEEAKQHGGSKRPSDSSRPK 524
+ R + DK+ + + G E + ++ + EE +Q + + +
Sbjct: 953 RQERERQYRKDKKLQQKEEQLLGEEPEKRRRQEREKKYREEEELQQEEEQLLREEREKRR 1012
Query: 525 EHEHEGKKRRKE 536
E E + R+K+
Sbjct: 1013 RQEWERQYRKKD 1024
Score = 31.2 bits (69), Expect = 2.5
Identities = 23/113 (20%), Positives = 50/113 (44%), Gaps = 19/113 (16%)
Query: 294 ADRKAREAVEMRAQVERKMAQKEK--------------EKHEEKLREMAQKARERRAGIK 339
+DRK RE ++R + E + + ++ E+ E++LR+ R+R+ +
Sbjct: 1793 SDRKFREEEQLRQEREEQQLRPQQRDGKYRWEEEQLQLEEQEQRLRQ----ERDRQYRAE 1848
Query: 340 THVEKEDGEARERDEI-RHDRRKERQHDRNLSRAAPDKRSKLQRNENRDISEV 391
++ RE E+ + + +K RQ R +R + + +R + E+
Sbjct: 1849 EQFATQEKSRREEQELWQEEEQKRRQERERKLREEHIRRQQKEEQRHRQVGEI 1901
Score = 30.8 bits (68), Expect = 3.3
Identities = 27/115 (23%), Positives = 54/115 (46%), Gaps = 14/115 (12%)
Query: 286 KLAEALYIA-------DRKAREAVEMRAQVERKMAQKEKEKH-EEKLREMAQKARERRAG 337
K+A+A Y A D + R + + + + Q+E ++ E + R++ ++ +RR
Sbjct: 80 KVAQACYYALGQATGLDEEKRARCDGKESLLQDRRQEEDQRRFEPRDRQLEEEPGQRRRQ 139
Query: 338 IKTHVEKE--DGEARERDEIRHDRRKERQHDRNLSRAAPDKRSKLQRNENRDISE 390
+ E+E +GE + + R ++R ++ D L R +R + Q E R E
Sbjct: 140 KRQEQERELAEGEEQSEKQERLEQRDRQRRDEELWR----QRQEWQEREERRAEE 190
Score = 30.8 bits (68), Expect = 3.3
Identities = 25/107 (23%), Positives = 53/107 (49%), Gaps = 15/107 (14%)
Query: 295 DRKAREAVEM--RAQVERKMAQKEKE----------KHEEKLREMAQKARERRAGIKTHV 342
DRK RE + R + ERK Q+E++ + EE+LR+ ++ + RR +
Sbjct: 1690 DRKFREEEQQLRRQERERKFLQEEQQLRRQELERKFREEEQLRQETEQEQLRRQERYRKI 1749
Query: 343 EKEDGEARERDE---IRHDRRKERQHDRNLSRAAPDKRSKLQRNENR 386
+E+ ER+E R +R ++ + + L + +++ + Q ++ +
Sbjct: 1750 LEEEQLRPEREEQQLRRQERDRKFREEEQLRQEREEQQLRSQESDRK 1796
Score = 30.4 bits (67), Expect = 4.2
Identities = 22/93 (23%), Positives = 46/93 (49%), Gaps = 4/93 (4%)
Query: 294 ADRKAREAVEMRAQVERKMAQKEKEKHEEKL--REMAQKARERRAGIKTHVEKEDGEARE 351
A R+ +E + R + A+++ E+ ++L R ++ RER+ + ++E E
Sbjct: 754 AHRQQQEEEQRRDFTWQWQAEEKSERGRQRLSARPPLREQRERQLRAEERQQREQRFLPE 813
Query: 352 RDEIRHDRRKERQHDRNLSRAAPDKRSKLQRNE 384
+E RR+ R+ ++ L ++ +LQR E
Sbjct: 814 EEEKEQRRRQRREREKELQFL--EEEEQLQRRE 844
Score = 30.0 bits (66), Expect = 5.5
Identities = 38/170 (22%), Positives = 68/170 (40%), Gaps = 41/170 (24%)
Query: 263 PLDKRLAADGRGLQTVHINENFAKLAEALYIADRKAREAVEMRAQVERKMAQKEKEKHEE 322
P D++L + + E +LAE E +++ + ++ Q+++++ +E
Sbjct: 124 PRDRQLEEEPGQRRRQKRQEQERELAEG------------EEQSEKQERLEQRDRQRRDE 171
Query: 323 KL---REMAQKARERRA------GIKTHVEKE--DGEARERDEIRHDRRKERQHDRNLSR 371
+L R+ Q+ ERRA K H +E D E R E+ RRK R+ + R
Sbjct: 172 ELWRQRQEWQEREERRAEEEQLQSCKGHETEEFPDEEQLRRRELLELRRKGREEKQQQRR 231
Query: 372 AAPD------------KRSKLQRNENRDISEVIALGVPNPRTSNEVQYDQ 409
D KR + R E + E P+ E+Q ++
Sbjct: 232 ERQDRVFQEEEEKEWRKRETVLRKEEEKLQE------EEPQRQRELQEEE 275
Score = 30.0 bits (66), Expect = 5.5
Identities = 18/93 (19%), Positives = 48/93 (51%), Gaps = 7/93 (7%)
Query: 296 RKAREAVEMRAQVERKMAQKEKEKHEEKLREMAQKARERRAGIKTHVEKEDGEARERDE- 354
R+ ++R + +RK + E+ E + +++ ++ R+R+ +E+E R+ E
Sbjct: 1605 RRQEGQQQLRQERDRKFREDEQLLQEREEQQLHRQERDRK-----FLEEEPQLRRQEREQ 1659
Query: 355 -IRHDRRKERQHDRNLSRAAPDKRSKLQRNENR 386
+RHDR ++ + + L + +++ + Q + +
Sbjct: 1660 QLRHDRDRKFREEEQLLQEGEEQQLRRQERDRK 1692
Score = 30.0 bits (66), Expect = 5.5
Identities = 24/105 (22%), Positives = 49/105 (46%), Gaps = 12/105 (11%)
Query: 295 DRKAREAVEM----------RAQVERKMAQKEKE-KHEEKLREMAQKARERRAGIKTHVE 343
DRK RE ++ R + +RK ++E++ + +E+ R+ Q+ ++ R
Sbjct: 1666 DRKFREEEQLLQEGEEQQLRRQERDRKFREEEQQLRRQERERKFLQEEQQLRRQELERKF 1725
Query: 344 KEDGEARERDEIRHDRRKERQHD-RNLSRAAPDKRSKLQRNENRD 387
+E+ + R+ E RR+ER + P++ + R + RD
Sbjct: 1726 REEEQLRQETEQEQLRRQERYRKILEEEQLRPEREEQQLRRQERD 1770
Score = 29.6 bits (65), Expect = 7.2
Identities = 21/97 (21%), Positives = 47/97 (48%), Gaps = 4/97 (4%)
Query: 295 DRKAREAVEMRAQVERKMAQKE----KEKHEEKLREMAQKARERRAGIKTHVEKEDGEAR 350
+RK RE ++R + E++ +++ K EE+LR ++ + RR +E+ +
Sbjct: 1722 ERKFREEEQLRQETEQEQLRRQERYRKILEEEQLRPEREEQQLRRQERDRKFREEEQLRQ 1781
Query: 351 ERDEIRHDRRKERQHDRNLSRAAPDKRSKLQRNENRD 387
ER+E + ++ + R + ++ + R + RD
Sbjct: 1782 EREEQQLRSQESDRKFREEEQLRQEREEQQLRPQQRD 1818
Score = 29.3 bits (64), Expect = 9.5
Identities = 23/99 (23%), Positives = 47/99 (47%), Gaps = 10/99 (10%)
Query: 295 DRKAREAVEMRAQVERKMAQKEKEKHEEK--LREMAQKARER-------RAGIKTHVEKE 345
DR E ++ + +++ +++++ EEK LRE ++ R R R + E+E
Sbjct: 1290 DRHFPEEEQLEREEQKEAKRRDRKSQEEKQLLREEREEKRRRQETDRKFREEEQLLQERE 1349
Query: 346 DGEARERDEIRHDRRKERQHDRNLSRAAPDKRSKLQRNE 384
+ R ++ R R +E +H R ++ +L+R E
Sbjct: 1350 EQPLRRQERDRKFREEELRHQEQ-GRKFLEEEQRLRRQE 1387
Score = 29.3 bits (64), Expect = 9.5
Identities = 18/96 (18%), Positives = 48/96 (50%), Gaps = 3/96 (3%)
Query: 296 RKAREAVEMRAQVERKMAQKEKEKHEEKLREMAQKARERRAGIKTH-VEKEDGEARERDE 354
R+ + R +RK ++E+ + E + ++++++ R+R+ ++ V +++ E + ++
Sbjct: 1541 RRQERGQQRRQDRDRKFREEEQLRQEREEQQLSRQERDRKFRLEEQKVRRQEQERKFMED 1600
Query: 355 IRHDRRKERQHD--RNLSRAAPDKRSKLQRNENRDI 388
+ RR+E Q + R + LQ E + +
Sbjct: 1601 EQQLRRQEGQQQLRQERDRKFREDEQLLQEREEQQL 1636
>gi|50513245 chromatin assembly factor 1, subunit A (p150) [Homo
sapiens]
Length = 956
Score = 43.9 bits (102), Expect = 4e-04
Identities = 29/100 (29%), Positives = 52/100 (52%), Gaps = 10/100 (10%)
Query: 296 RKAREAVEMRAQVERKMAQKEKEKHEEKLREMAQKARERRAGIKTHVEKEDGEARERDE- 354
R R+ + Q++ + ++EKEK +E+ + ++A++++ K EKE E RE+DE
Sbjct: 336 RLQRDQERLGKQLKLRAEREEKEKLKEEAKRAKEEAKKKKEEEKELKEKERREKREKDEK 395
Query: 355 -------IRHDRRKERQHDRNLSRAAPDKRSKLQRNENRD 387
++ +RRKERQ L +KR K + R+
Sbjct: 396 EKAEKQRLKEERRKERQ--EALEAKLEEKRKKEEEKRLRE 433
>gi|31377595 zinc finger CCCH-type containing 18 [Homo sapiens]
Length = 953
Score = 43.9 bits (102), Expect = 4e-04
Identities = 27/99 (27%), Positives = 46/99 (46%), Gaps = 14/99 (14%)
Query: 303 EMRAQVERKMAQKEKEKHEEKLREMAQKARERRAGIKTHVEKEDGEARERDEIRHDRRKE 362
E + ER+ Q+E+E+ E+ RE ++ RER RER+ R R+
Sbjct: 403 ERERERERENRQRERERERERDRERERRQRERE--------------REREHERDKERQR 448
Query: 363 RQHDRNLSRAAPDKRSKLQRNENRDISEVIALGVPNPRT 401
R+ + RA D++ + R+ +R+ G P PR+
Sbjct: 449 RKEEWERERAKRDEKDRQHRDRDREKEREKEKGKPKPRS 487
Score = 35.8 bits (81), Expect = 0.10
Identities = 22/80 (27%), Positives = 39/80 (48%), Gaps = 6/80 (7%)
Query: 295 DRKAREAVEMRAQVERKMAQKEKEKHEEKLREMAQKARERRAGIKTHVEKEDGEARERDE 354
+R+ E ER+ Q+E+E+ E R+ K R+RR K E+E + E+D
Sbjct: 412 NRQRERERERERDRERERRQREREREREHERD---KERQRR---KEEWERERAKRDEKDR 465
Query: 355 IRHDRRKERQHDRNLSRAAP 374
DR +E++ ++ + P
Sbjct: 466 QHRDRDREKEREKEKGKPKP 485
Score = 31.6 bits (70), Expect = 1.9
Identities = 20/85 (23%), Positives = 41/85 (48%), Gaps = 4/85 (4%)
Query: 297 KAREAVEMRAQVERKMAQKEKEKHEEKLREMAQKARERRAGIKTHVEKEDGE---ARERD 353
+ RE Q ER+ ++E+++ E+ + ++ RE + KE+ E A+ +
Sbjct: 404 RERERERENRQRERER-ERERDRERERRQREREREREHERDKERQRRKEEWERERAKRDE 462
Query: 354 EIRHDRRKERQHDRNLSRAAPDKRS 378
+ R R ++R+ +R + P RS
Sbjct: 463 KDRQHRDRDREKEREKEKGKPKPRS 487
>gi|156766047 GRB10 interacting GYF protein 2 isoform c [Homo
sapiens]
Length = 1293
Score = 43.5 bits (101), Expect = 5e-04
Identities = 44/221 (19%), Positives = 94/221 (42%), Gaps = 23/221 (10%)
Query: 171 LAPAQYIRYTPSQQGVAFNSGAKQRVIRMVEMQKDPMEPPRFKINKKIPRGPPSPPAPVM 230
L QY + QQ A +S +Q++ +++ + + +I+ + ++
Sbjct: 625 LIQQQYAQVLAQQQKAALSSQQQQQLALLLQQ----FQTLKMRISDQ----------NII 670
Query: 231 HSPSRKMTVKEQQE-WKIPPCISN---WKNAKGYTIPLDKRLAADGRGLQTVHINENFAK 286
S +R ++V + W++ P S W+ + +PLD G L+ + + K
Sbjct: 671 PSVTRSVSVPDTGSIWELQPTASQPTVWEGGSVWDLPLDT--TTPGPALEQL---QQLEK 725
Query: 287 LAEALYIADRKAREAVEMRAQVERKMAQKEKEKHEEKLREMAQKARERRAGIKTHVEKED 346
A +R+ E R + ERK ++ + + EE LR ++ R+RR + K++
Sbjct: 726 AKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRREEEELARRKQE 785
Query: 347 GEARERDEIRHDRRKERQHDRNLSRAAPDKRSKLQRNENRD 387
R + E R++R+ + + +R + +R E +
Sbjct: 786 EALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEE 826
Score = 35.8 bits (81), Expect = 0.10
Identities = 32/136 (23%), Positives = 59/136 (43%), Gaps = 14/136 (10%)
Query: 282 ENFAKLAEALYIADRKAREAVEMRAQVERKMAQKEKEKHEEKLREMAQKARERRAGIKTH 341
E K E +A RK EA+ + + E + ++ +E+ ++ E ++ ERR
Sbjct: 768 EEERKRREEEELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERR------ 821
Query: 342 VEKEDGEARERDEIRHDRRKERQHDRNLSRAAPDKRSKLQRNENRDISEVIAL---GVPN 398
+E+ E R+++E+ RK+ + +R + + +L+ N R E L
Sbjct: 822 --REEEERRKQEEL---LRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEER 876
Query: 399 PRTSNEVQYDQRLFNQ 414
R EVQ + L Q
Sbjct: 877 KRKELEVQRQKELMRQ 892
Score = 34.3 bits (77), Expect = 0.29
Identities = 28/103 (27%), Positives = 45/103 (43%), Gaps = 11/103 (10%)
Query: 293 IADRKAREAVEMRAQVE-------RKMAQKEKEKHEEKLR----EMAQKARERRAGIKTH 341
IA R+ RE E + Q E R+ ++E+ K EE LR E A+ ARE +
Sbjct: 796 IALRRQREEEERQQQEEALRRLEERRREEEERRKQEELLRKQEEEAAKWAREEEEAQRRL 855
Query: 342 VEKEDGEARERDEIRHDRRKERQHDRNLSRAAPDKRSKLQRNE 384
E E +RH+ + ++ + + R R + Q+ E
Sbjct: 856 EENRLRMEEEAARLRHEEEERKRKELEVQRQKELMRQRQQQQE 898
Score = 32.3 bits (72), Expect = 1.1
Identities = 29/104 (27%), Positives = 49/104 (47%), Gaps = 13/104 (12%)
Query: 289 EALYIADRKAREAVEMRAQVE--RKMAQ------KEKEKHEEKLREMAQKARERRAGIKT 340
EAL + + RE E R Q E RK + +E+E+ + +L E + E A ++
Sbjct: 812 EALRRLEERRREEEERRKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLR- 870
Query: 341 HVEKEDGEARERDEIRHDRRKERQHDRNLSRAAPDKRSKLQRNE 384
H E+E R+R E+ R+KE R + A + + Q+ +
Sbjct: 871 HEEEE----RKRKELEVQRQKELMRQRQQQQEALRRLQQQQQQQ 910
>gi|156766045 GRB10 interacting GYF protein 2 isoform a [Homo
sapiens]
Length = 1320
Score = 43.5 bits (101), Expect = 5e-04
Identities = 44/221 (19%), Positives = 94/221 (42%), Gaps = 23/221 (10%)
Query: 171 LAPAQYIRYTPSQQGVAFNSGAKQRVIRMVEMQKDPMEPPRFKINKKIPRGPPSPPAPVM 230
L QY + QQ A +S +Q++ +++ + + +I+ + ++
Sbjct: 652 LIQQQYAQVLAQQQKAALSSQQQQQLALLLQQ----FQTLKMRISDQ----------NII 697
Query: 231 HSPSRKMTVKEQQE-WKIPPCISN---WKNAKGYTIPLDKRLAADGRGLQTVHINENFAK 286
S +R ++V + W++ P S W+ + +PLD G L+ + + K
Sbjct: 698 PSVTRSVSVPDTGSIWELQPTASQPTVWEGGSVWDLPLDT--TTPGPALEQL---QQLEK 752
Query: 287 LAEALYIADRKAREAVEMRAQVERKMAQKEKEKHEEKLREMAQKARERRAGIKTHVEKED 346
A +R+ E R + ERK ++ + + EE LR ++ R+RR + K++
Sbjct: 753 AKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRREEEELARRKQE 812
Query: 347 GEARERDEIRHDRRKERQHDRNLSRAAPDKRSKLQRNENRD 387
R + E R++R+ + + +R + +R E +
Sbjct: 813 EALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEE 853
Score = 35.8 bits (81), Expect = 0.10
Identities = 32/136 (23%), Positives = 59/136 (43%), Gaps = 14/136 (10%)
Query: 282 ENFAKLAEALYIADRKAREAVEMRAQVERKMAQKEKEKHEEKLREMAQKARERRAGIKTH 341
E K E +A RK EA+ + + E + ++ +E+ ++ E ++ ERR
Sbjct: 795 EEERKRREEEELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERR------ 848
Query: 342 VEKEDGEARERDEIRHDRRKERQHDRNLSRAAPDKRSKLQRNENRDISEVIAL---GVPN 398
+E+ E R+++E+ RK+ + +R + + +L+ N R E L
Sbjct: 849 --REEEERRKQEEL---LRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEER 903
Query: 399 PRTSNEVQYDQRLFNQ 414
R EVQ + L Q
Sbjct: 904 KRKELEVQRQKELMRQ 919
Score = 34.3 bits (77), Expect = 0.29
Identities = 28/103 (27%), Positives = 45/103 (43%), Gaps = 11/103 (10%)
Query: 293 IADRKAREAVEMRAQVE-------RKMAQKEKEKHEEKLR----EMAQKARERRAGIKTH 341
IA R+ RE E + Q E R+ ++E+ K EE LR E A+ ARE +
Sbjct: 823 IALRRQREEEERQQQEEALRRLEERRREEEERRKQEELLRKQEEEAAKWAREEEEAQRRL 882
Query: 342 VEKEDGEARERDEIRHDRRKERQHDRNLSRAAPDKRSKLQRNE 384
E E +RH+ + ++ + + R R + Q+ E
Sbjct: 883 EENRLRMEEEAARLRHEEEERKRKELEVQRQKELMRQRQQQQE 925
Score = 32.3 bits (72), Expect = 1.1
Identities = 29/104 (27%), Positives = 49/104 (47%), Gaps = 13/104 (12%)
Query: 289 EALYIADRKAREAVEMRAQVE--RKMAQ------KEKEKHEEKLREMAQKARERRAGIKT 340
EAL + + RE E R Q E RK + +E+E+ + +L E + E A ++
Sbjct: 839 EALRRLEERRREEEERRKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLR- 897
Query: 341 HVEKEDGEARERDEIRHDRRKERQHDRNLSRAAPDKRSKLQRNE 384
H E+E R+R E+ R+KE R + A + + Q+ +
Sbjct: 898 HEEEE----RKRKELEVQRQKELMRQRQQQQEALRRLQQQQQQQ 937
>gi|156766043 GRB10 interacting GYF protein 2 isoform b [Homo
sapiens]
Length = 1299
Score = 43.5 bits (101), Expect = 5e-04
Identities = 44/221 (19%), Positives = 94/221 (42%), Gaps = 23/221 (10%)
Query: 171 LAPAQYIRYTPSQQGVAFNSGAKQRVIRMVEMQKDPMEPPRFKINKKIPRGPPSPPAPVM 230
L QY + QQ A +S +Q++ +++ + + +I+ + ++
Sbjct: 631 LIQQQYAQVLAQQQKAALSSQQQQQLALLLQQ----FQTLKMRISDQ----------NII 676
Query: 231 HSPSRKMTVKEQQE-WKIPPCISN---WKNAKGYTIPLDKRLAADGRGLQTVHINENFAK 286
S +R ++V + W++ P S W+ + +PLD G L+ + + K
Sbjct: 677 PSVTRSVSVPDTGSIWELQPTASQPTVWEGGSVWDLPLDT--TTPGPALEQL---QQLEK 731
Query: 287 LAEALYIADRKAREAVEMRAQVERKMAQKEKEKHEEKLREMAQKARERRAGIKTHVEKED 346
A +R+ E R + ERK ++ + + EE LR ++ R+RR + K++
Sbjct: 732 AKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRREEEELARRKQE 791
Query: 347 GEARERDEIRHDRRKERQHDRNLSRAAPDKRSKLQRNENRD 387
R + E R++R+ + + +R + +R E +
Sbjct: 792 EALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEE 832
Score = 35.8 bits (81), Expect = 0.10
Identities = 32/136 (23%), Positives = 59/136 (43%), Gaps = 14/136 (10%)
Query: 282 ENFAKLAEALYIADRKAREAVEMRAQVERKMAQKEKEKHEEKLREMAQKARERRAGIKTH 341
E K E +A RK EA+ + + E + ++ +E+ ++ E ++ ERR
Sbjct: 774 EEERKRREEEELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERR------ 827
Query: 342 VEKEDGEARERDEIRHDRRKERQHDRNLSRAAPDKRSKLQRNENRDISEVIAL---GVPN 398
+E+ E R+++E+ RK+ + +R + + +L+ N R E L
Sbjct: 828 --REEEERRKQEEL---LRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEER 882
Query: 399 PRTSNEVQYDQRLFNQ 414
R EVQ + L Q
Sbjct: 883 KRKELEVQRQKELMRQ 898
Score = 34.3 bits (77), Expect = 0.29
Identities = 28/103 (27%), Positives = 45/103 (43%), Gaps = 11/103 (10%)
Query: 293 IADRKAREAVEMRAQVE-------RKMAQKEKEKHEEKLR----EMAQKARERRAGIKTH 341
IA R+ RE E + Q E R+ ++E+ K EE LR E A+ ARE +
Sbjct: 802 IALRRQREEEERQQQEEALRRLEERRREEEERRKQEELLRKQEEEAAKWAREEEEAQRRL 861
Query: 342 VEKEDGEARERDEIRHDRRKERQHDRNLSRAAPDKRSKLQRNE 384
E E +RH+ + ++ + + R R + Q+ E
Sbjct: 862 EENRLRMEEEAARLRHEEEERKRKELEVQRQKELMRQRQQQQE 904
Score = 32.3 bits (72), Expect = 1.1
Identities = 29/104 (27%), Positives = 49/104 (47%), Gaps = 13/104 (12%)
Query: 289 EALYIADRKAREAVEMRAQVE--RKMAQ------KEKEKHEEKLREMAQKARERRAGIKT 340
EAL + + RE E R Q E RK + +E+E+ + +L E + E A ++
Sbjct: 818 EALRRLEERRREEEERRKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLR- 876
Query: 341 HVEKEDGEARERDEIRHDRRKERQHDRNLSRAAPDKRSKLQRNE 384
H E+E R+R E+ R+KE R + A + + Q+ +
Sbjct: 877 HEEEE----RKRKELEVQRQKELMRQRQQQQEALRRLQQQQQQQ 916
>gi|42476299 GRB10 interacting GYF protein 2 isoform b [Homo
sapiens]
Length = 1299
Score = 43.5 bits (101), Expect = 5e-04
Identities = 44/221 (19%), Positives = 94/221 (42%), Gaps = 23/221 (10%)
Query: 171 LAPAQYIRYTPSQQGVAFNSGAKQRVIRMVEMQKDPMEPPRFKINKKIPRGPPSPPAPVM 230
L QY + QQ A +S +Q++ +++ + + +I+ + ++
Sbjct: 631 LIQQQYAQVLAQQQKAALSSQQQQQLALLLQQ----FQTLKMRISDQ----------NII 676
Query: 231 HSPSRKMTVKEQQE-WKIPPCISN---WKNAKGYTIPLDKRLAADGRGLQTVHINENFAK 286
S +R ++V + W++ P S W+ + +PLD G L+ + + K
Sbjct: 677 PSVTRSVSVPDTGSIWELQPTASQPTVWEGGSVWDLPLDT--TTPGPALEQL---QQLEK 731
Query: 287 LAEALYIADRKAREAVEMRAQVERKMAQKEKEKHEEKLREMAQKARERRAGIKTHVEKED 346
A +R+ E R + ERK ++ + + EE LR ++ R+RR + K++
Sbjct: 732 AKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRREEEELARRKQE 791
Query: 347 GEARERDEIRHDRRKERQHDRNLSRAAPDKRSKLQRNENRD 387
R + E R++R+ + + +R + +R E +
Sbjct: 792 EALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEE 832
Score = 35.8 bits (81), Expect = 0.10
Identities = 32/136 (23%), Positives = 59/136 (43%), Gaps = 14/136 (10%)
Query: 282 ENFAKLAEALYIADRKAREAVEMRAQVERKMAQKEKEKHEEKLREMAQKARERRAGIKTH 341
E K E +A RK EA+ + + E + ++ +E+ ++ E ++ ERR
Sbjct: 774 EEERKRREEEELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERR------ 827
Query: 342 VEKEDGEARERDEIRHDRRKERQHDRNLSRAAPDKRSKLQRNENRDISEVIAL---GVPN 398
+E+ E R+++E+ RK+ + +R + + +L+ N R E L
Sbjct: 828 --REEEERRKQEEL---LRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEER 882
Query: 399 PRTSNEVQYDQRLFNQ 414
R EVQ + L Q
Sbjct: 883 KRKELEVQRQKELMRQ 898
Score = 34.3 bits (77), Expect = 0.29
Identities = 28/103 (27%), Positives = 45/103 (43%), Gaps = 11/103 (10%)
Query: 293 IADRKAREAVEMRAQVE-------RKMAQKEKEKHEEKLR----EMAQKARERRAGIKTH 341
IA R+ RE E + Q E R+ ++E+ K EE LR E A+ ARE +
Sbjct: 802 IALRRQREEEERQQQEEALRRLEERRREEEERRKQEELLRKQEEEAAKWAREEEEAQRRL 861
Query: 342 VEKEDGEARERDEIRHDRRKERQHDRNLSRAAPDKRSKLQRNE 384
E E +RH+ + ++ + + R R + Q+ E
Sbjct: 862 EENRLRMEEEAARLRHEEEERKRKELEVQRQKELMRQRQQQQE 904
Score = 32.3 bits (72), Expect = 1.1
Identities = 29/104 (27%), Positives = 49/104 (47%), Gaps = 13/104 (12%)
Query: 289 EALYIADRKAREAVEMRAQVE--RKMAQ------KEKEKHEEKLREMAQKARERRAGIKT 340
EAL + + RE E R Q E RK + +E+E+ + +L E + E A ++
Sbjct: 818 EALRRLEERRREEEERRKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLR- 876
Query: 341 HVEKEDGEARERDEIRHDRRKERQHDRNLSRAAPDKRSKLQRNE 384
H E+E R+R E+ R+KE R + A + + Q+ +
Sbjct: 877 HEEEE----RKRKELEVQRQKELMRQRQQQQEALRRLQQQQQQQ 916
>gi|239745153 PREDICTED: similar to Putative golgin subfamily A
member 6-like protein 6 [Homo sapiens]
Length = 655
Score = 43.5 bits (101), Expect = 5e-04
Identities = 50/252 (19%), Positives = 111/252 (44%), Gaps = 25/252 (9%)
Query: 276 QTVHINENFAKLAEALYIADRKAREAVEMRAQVERKMAQKEKE-KHEEKLREMAQKARER 334
Q I E K+ E ++ R+ ++R Q E+ Q+E+ + EEK+RE +K +E+
Sbjct: 351 QEEKIREQEEKIREQ---EEKMWRQEEKIREQDEKIQEQEEEMWRQEEKIREQEEKRQEK 407
Query: 335 RAGIKTHVEKEDGEARERDEIRHDRRKERQHDRNLSRAAPDKRSKLQRNENRDISEVIAL 394
+ + ++D + RE++E + ++ + R L D+ KL+ E + E +
Sbjct: 408 MWRQEKKMREQDEKIREQEE---EMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEEKM 464
Query: 395 GVPNPRTSNE----VQYDQRLFNQSKGMDSGFAGGEDEIYNVYDQAWRGGKDMAQSIYRP 450
+ + + +++ + Q K + E++I+ ++ WR + M +
Sbjct: 465 QEQEEKIQRQEEKIQEQEEKTWRQEKLLKQ-----EEKIWEQEEKMWRQEEKMWE----- 514
Query: 451 SKNLDKDMYGDDLEARIKTNRFVPDKEFSGSDRRQRGREGPVQFEEDPFGLDKFLEEAKQ 510
++ + E + + ++E + ++ +E V+ +E L K ++A+
Sbjct: 515 ----QEEKMQEQEEKMQRQEEKMREQEVRLWQQEEKMQEQEVRLQELEERLGKLGQKAEL 570
Query: 511 HGGSKRPSDSSR 522
GG+ R S S R
Sbjct: 571 LGGAGRESGSQR 582
Score = 32.0 bits (71), Expect = 1.5
Identities = 51/245 (20%), Positives = 98/245 (40%), Gaps = 31/245 (12%)
Query: 307 QVERKMAQKEK-EKHEEKLREMAQKARER-----RAGIKTHV------EKEDGEARERDE 354
Q E+ Q+EK ++ EEK+ E K RE+ R K H E+ED R+ ++
Sbjct: 295 QEEKMWRQEEKIQEQEEKMCEQELKIREQEEKMWRQEEKMHEQEEKIREQEDKMWRQEEK 354
Query: 355 IRHDRRKERQHDRNLSRAAPDKRSKLQRNENRDISEVIALGVPNPRTSNEVQYDQRLFNQ 414
IR K R+ + + R R +++E E E + ++++ Q
Sbjct: 355 IREQEEKIREQEEKMWRQEEKIR---EQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQ 411
Query: 415 SKGM---DSGFAGGEDEIYNVYDQAWRGGKDMAQSIYRPSKNLDKDMYGDDLEARIKTNR 471
K M D E+E++ ++ R ++M Q + +++ M ++
Sbjct: 412 EKKMREQDEKIREQEEEMWR-QEEKIRELEEMMQDQEEKLREVEEKMQEEE--------- 461
Query: 472 FVPDKEFSGSDRRQRGREGPVQFEEDPFGLDKFLEEAKQHGGSKRPSDSSRPKEHEHEGK 531
+K ++ QR E + EE + +K L++ ++ + K E E K
Sbjct: 462 ---EKMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQEEKMWRQEEKMWEQEEK 518
Query: 532 KRRKE 536
+ +E
Sbjct: 519 MQEQE 523
>gi|239745127 PREDICTED: similar to Putative golgin subfamily A
member 6-like protein 6 [Homo sapiens]
Length = 655
Score = 43.5 bits (101), Expect = 5e-04
Identities = 50/252 (19%), Positives = 111/252 (44%), Gaps = 25/252 (9%)
Query: 276 QTVHINENFAKLAEALYIADRKAREAVEMRAQVERKMAQKEKE-KHEEKLREMAQKARER 334
Q I E K+ E ++ R+ ++R Q E+ Q+E+ + EEK+RE +K +E+
Sbjct: 351 QEEKIREQEEKIREQ---EEKMWRQEEKIREQDEKIQEQEEEMWRQEEKIREQEEKRQEK 407
Query: 335 RAGIKTHVEKEDGEARERDEIRHDRRKERQHDRNLSRAAPDKRSKLQRNENRDISEVIAL 394
+ + ++D + RE++E + ++ + R L D+ KL+ E + E +
Sbjct: 408 MWRQEKKMREQDEKIREQEE---EMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEEKM 464
Query: 395 GVPNPRTSNE----VQYDQRLFNQSKGMDSGFAGGEDEIYNVYDQAWRGGKDMAQSIYRP 450
+ + + +++ + Q K + E++I+ ++ WR + M +
Sbjct: 465 QEQEEKIQRQEEKIQEQEEKTWRQEKLLKQ-----EEKIWEQEEKMWRQEEKMWE----- 514
Query: 451 SKNLDKDMYGDDLEARIKTNRFVPDKEFSGSDRRQRGREGPVQFEEDPFGLDKFLEEAKQ 510
++ + E + + ++E + ++ +E V+ +E L K ++A+
Sbjct: 515 ----QEEKMQEQEEKMQRQEEKMREQEVRLWQQEEKMQEQEVRLQELEERLGKLGQKAEL 570
Query: 511 HGGSKRPSDSSR 522
GG+ R S S R
Sbjct: 571 LGGAGRESGSQR 582
Score = 32.0 bits (71), Expect = 1.5
Identities = 51/245 (20%), Positives = 98/245 (40%), Gaps = 31/245 (12%)
Query: 307 QVERKMAQKEK-EKHEEKLREMAQKARER-----RAGIKTHV------EKEDGEARERDE 354
Q E+ Q+EK ++ EEK+ E K RE+ R K H E+ED R+ ++
Sbjct: 295 QEEKMWRQEEKIQEQEEKMCEQELKIREQEEKMWRQEEKMHEQEEKIREQEDKMWRQEEK 354
Query: 355 IRHDRRKERQHDRNLSRAAPDKRSKLQRNENRDISEVIALGVPNPRTSNEVQYDQRLFNQ 414
IR K R+ + + R R +++E E E + ++++ Q
Sbjct: 355 IREQEEKIREQEEKMWRQEEKIR---EQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQ 411
Query: 415 SKGM---DSGFAGGEDEIYNVYDQAWRGGKDMAQSIYRPSKNLDKDMYGDDLEARIKTNR 471
K M D E+E++ ++ R ++M Q + +++ M ++
Sbjct: 412 EKKMREQDEKIREQEEEMWR-QEEKIRELEEMMQDQEEKLREVEEKMQEEE--------- 461
Query: 472 FVPDKEFSGSDRRQRGREGPVQFEEDPFGLDKFLEEAKQHGGSKRPSDSSRPKEHEHEGK 531
+K ++ QR E + EE + +K L++ ++ + K E E K
Sbjct: 462 ---EKMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQEEKMWRQEEKMWEQEEK 518
Query: 532 KRRKE 536
+ +E
Sbjct: 519 MQEQE 523
>gi|194294523 intersectin 2 isoform 3 [Homo sapiens]
Length = 1670
Score = 43.5 bits (101), Expect = 5e-04
Identities = 31/106 (29%), Positives = 59/106 (55%), Gaps = 9/106 (8%)
Query: 297 KAREAV--EMRAQVERKMAQKEKEKHEEKLREMAQKARERRAGIKTHVEKEDGEARERDE 354
K R+A+ + + + ERK AQKEKE+ E K RE+ ++ +++ ++ +EK+ R+R+E
Sbjct: 380 KRRQALMEQQQREAERK-AQKEKEEWERKQRELQEQEWKKQLELEKRLEKQRELERQREE 438
Query: 355 IRH---DRRKERQHDRNLSRAAP---DKRSKLQRNENRDISEVIAL 394
R +RR+ + + R +R +L +NR+ E++ L
Sbjct: 439 ERRKDIERREAAKQELERQRRLEWERIRRQELLNQKNREQEEIVRL 484
Score = 32.0 bits (71), Expect = 1.5
Identities = 22/91 (24%), Positives = 42/91 (46%), Gaps = 7/91 (7%)
Query: 296 RKAREAVEMRAQVERKMAQKEKEKHEEKLREMAQKARERRAGIKTHVEKEDGEARERDEI 355
+K E + + + E EK + L E Q+ ER+A EKE+ E ++R+
Sbjct: 357 KKLPVTFEDKRKANYERGNMELEKRRQALMEQQQREAERKA----QKEKEEWERKQRELQ 412
Query: 356 RHDRRKERQHDRNLSRAAPDKRSKLQRNENR 386
+ +K+ + ++ L + + + QR E R
Sbjct: 413 EQEWKKQLELEKRLEK---QRELERQREEER 440
Score = 31.6 bits (70), Expect = 1.9
Identities = 18/59 (30%), Positives = 34/59 (57%), Gaps = 6/59 (10%)
Query: 294 ADRKAREAVE------MRAQVERKMAQKEKEKHEEKLREMAQKARERRAGIKTHVEKED 346
A RKA++ E +R + E K + ++EK +EK++E +KA E++ K ++ E+
Sbjct: 665 AARKAKQGKENLWKENLRKEEEEKQKRLQEEKTQEKIQEEERKAEEKQRKDKDTLKAEE 723
>gi|194294521 intersectin 2 isoform 1 [Homo sapiens]
Length = 1697
Score = 43.5 bits (101), Expect = 5e-04
Identities = 31/106 (29%), Positives = 59/106 (55%), Gaps = 9/106 (8%)
Query: 297 KAREAV--EMRAQVERKMAQKEKEKHEEKLREMAQKARERRAGIKTHVEKEDGEARERDE 354
K R+A+ + + + ERK AQKEKE+ E K RE+ ++ +++ ++ +EK+ R+R+E
Sbjct: 380 KRRQALMEQQQREAERK-AQKEKEEWERKQRELQEQEWKKQLELEKRLEKQRELERQREE 438
Query: 355 IRH---DRRKERQHDRNLSRAAP---DKRSKLQRNENRDISEVIAL 394
R +RR+ + + R +R +L +NR+ E++ L
Sbjct: 439 ERRKDIERREAAKQELERQRRLEWERIRRQELLNQKNREQEEIVRL 484
Score = 32.0 bits (71), Expect = 1.5
Identities = 22/91 (24%), Positives = 42/91 (46%), Gaps = 7/91 (7%)
Query: 296 RKAREAVEMRAQVERKMAQKEKEKHEEKLREMAQKARERRAGIKTHVEKEDGEARERDEI 355
+K E + + + E EK + L E Q+ ER+A EKE+ E ++R+
Sbjct: 357 KKLPVTFEDKRKANYERGNMELEKRRQALMEQQQREAERKA----QKEKEEWERKQRELQ 412
Query: 356 RHDRRKERQHDRNLSRAAPDKRSKLQRNENR 386
+ +K+ + ++ L + + + QR E R
Sbjct: 413 EQEWKKQLELEKRLEK---QRELERQREEER 440
Score = 31.6 bits (70), Expect = 1.9
Identities = 18/59 (30%), Positives = 34/59 (57%), Gaps = 6/59 (10%)
Query: 294 ADRKAREAVE------MRAQVERKMAQKEKEKHEEKLREMAQKARERRAGIKTHVEKED 346
A RKA++ E +R + E K + ++EK +EK++E +KA E++ K ++ E+
Sbjct: 692 AARKAKQGKENLWKENLRKEEEEKQKRLQEEKTQEKIQEEERKAEEKQRKDKDTLKAEE 750
>gi|194294525 intersectin 2 isoform 2 [Homo sapiens]
Length = 1249
Score = 43.5 bits (101), Expect = 5e-04
Identities = 31/106 (29%), Positives = 59/106 (55%), Gaps = 9/106 (8%)
Query: 297 KAREAV--EMRAQVERKMAQKEKEKHEEKLREMAQKARERRAGIKTHVEKEDGEARERDE 354
K R+A+ + + + ERK AQKEKE+ E K RE+ ++ +++ ++ +EK+ R+R+E
Sbjct: 380 KRRQALMEQQQREAERK-AQKEKEEWERKQRELQEQEWKKQLELEKRLEKQRELERQREE 438
Query: 355 IRH---DRRKERQHDRNLSRAAP---DKRSKLQRNENRDISEVIAL 394
R +RR+ + + R +R +L +NR+ E++ L
Sbjct: 439 ERRKDIERREAAKQELERQRRLEWERIRRQELLNQKNREQEEIVRL 484
Score = 32.0 bits (71), Expect = 1.5
Identities = 22/91 (24%), Positives = 42/91 (46%), Gaps = 7/91 (7%)
Query: 296 RKAREAVEMRAQVERKMAQKEKEKHEEKLREMAQKARERRAGIKTHVEKEDGEARERDEI 355
+K E + + + E EK + L E Q+ ER+A EKE+ E ++R+
Sbjct: 357 KKLPVTFEDKRKANYERGNMELEKRRQALMEQQQREAERKA----QKEKEEWERKQRELQ 412
Query: 356 RHDRRKERQHDRNLSRAAPDKRSKLQRNENR 386
+ +K+ + ++ L + + + QR E R
Sbjct: 413 EQEWKKQLELEKRLEK---QRELERQREEER 440
Score = 31.6 bits (70), Expect = 1.9
Identities = 18/59 (30%), Positives = 34/59 (57%), Gaps = 6/59 (10%)
Query: 294 ADRKAREAVE------MRAQVERKMAQKEKEKHEEKLREMAQKARERRAGIKTHVEKED 346
A RKA++ E +R + E K + ++EK +EK++E +KA E++ K ++ E+
Sbjct: 692 AARKAKQGKENLWKENLRKEEEEKQKRLQEEKTQEKIQEEERKAEEKQRKDKDTLKAEE 750
>gi|102467235 inner centromere protein antigens 135/155kDa isoform 1
[Homo sapiens]
Length = 918
Score = 43.5 bits (101), Expect = 5e-04
Identities = 56/286 (19%), Positives = 115/286 (40%), Gaps = 43/286 (15%)
Query: 192 AKQRVIRMVEMQKDPMEPPRFKINKKIPRGPPSPPAPVMHSPSRKMTVKEQQEWKIPPCI 251
A++RV +M E +K +E +I++K + A +K K+ +E
Sbjct: 584 ARERVEQMKEEKKKQIEQKFAQIDEKTEKAKEERLAE--EKAKKKAAAKKMEE------- 634
Query: 252 SNWKNAKGYTIPLDKRLAADGRGLQTVHINENFAKLAEALYIADRKAREAVEMRAQVERK 311
+ ++ + R L+ + E + E L + +E + A+ +R
Sbjct: 635 ----------VEARRKQEEEARRLRWLQQEEEERRHQELLQKKKEEEQERLRKAAEAKRL 684
Query: 312 MAQKEKEKHEEKLREMAQKARERRAGIKTHVEKEDGEARERDEIRHDRRKER---QHDRN 368
Q+E+E+ E++ RE ++ +ERR +++ +ER +RR+E+ Q +R
Sbjct: 685 AEQREQERREQERREQERREQERR--------EQERREQERQLAEQERRREQERLQAERE 736
Query: 369 LSRAAPDKRSKLQRNE-NRDISEVIALGVPNPRTSNEVQYDQRLFNQSKGMDSGFAGGED 427
L +K +LQ+ + R++ E + + + +R + + + A G
Sbjct: 737 LQER--EKALRLQKEQLQRELEE-------KKKKEEQQRLAERQLQEEQEKKAKEAAGAS 787
Query: 428 EIYNV---YDQAWRGGKDMAQSIYRPSKNLDKDMYGDDLEARIKTN 470
+ NV M +R ++ D YG DL + T+
Sbjct: 788 KALNVTVDVQSPACTSYQMTPQGHRAPPKINPDNYGMDLNSDDSTD 833
Score = 42.0 bits (97), Expect = 0.001
Identities = 51/206 (24%), Positives = 86/206 (41%), Gaps = 36/206 (17%)
Query: 201 EMQKDPMEPPRFKINKKIPRGPPSPPAPVMHSPSRKMTVKEQQEWKIPPCISNWKNAKGY 260
+M P PR + I R P+ P KE+Q + + +
Sbjct: 503 QMLMTPTSAPRSVMKSFIKRN-----TPLRMDPKCSFVEKERQRLENLRRKEEAEQLRRQ 557
Query: 261 TIPLDKRLAADGRGLQTVHINENFAKLAEALYIADRKAREAVEM-----RAQVERKMAQK 315
+ DKR R L+ V + +L + L +ARE VE + Q+E+K AQ
Sbjct: 558 KVEEDKR-----RRLEEVKLKRE-ERLRKVL-----QARERVEQMKEEKKKQIEQKFAQI 606
Query: 316 EKEKHEEKLREMAQKARERRAGIKTHVE-----KEDGEAR-------ERDEIRHD---RR 360
+++ + K +A++ +++A K E K++ EAR E +E RH ++
Sbjct: 607 DEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQEEEERRHQELLQK 666
Query: 361 KERQHDRNLSRAAPDKRSKLQRNENR 386
K+ + L +AA KR QR + R
Sbjct: 667 KKEEEQERLRKAAEAKRLAEQREQER 692
>gi|102467242 inner centromere protein antigens 135/155kDa isoform 2
[Homo sapiens]
Length = 914
Score = 43.5 bits (101), Expect = 5e-04
Identities = 56/286 (19%), Positives = 115/286 (40%), Gaps = 43/286 (15%)
Query: 192 AKQRVIRMVEMQKDPMEPPRFKINKKIPRGPPSPPAPVMHSPSRKMTVKEQQEWKIPPCI 251
A++RV +M E +K +E +I++K + A +K K+ +E
Sbjct: 580 ARERVEQMKEEKKKQIEQKFAQIDEKTEKAKEERLAE--EKAKKKAAAKKMEE------- 630
Query: 252 SNWKNAKGYTIPLDKRLAADGRGLQTVHINENFAKLAEALYIADRKAREAVEMRAQVERK 311
+ ++ + R L+ + E + E L + +E + A+ +R
Sbjct: 631 ----------VEARRKQEEEARRLRWLQQEEEERRHQELLQKKKEEEQERLRKAAEAKRL 680
Query: 312 MAQKEKEKHEEKLREMAQKARERRAGIKTHVEKEDGEARERDEIRHDRRKER---QHDRN 368
Q+E+E+ E++ RE ++ +ERR +++ +ER +RR+E+ Q +R
Sbjct: 681 AEQREQERREQERREQERREQERR--------EQERREQERQLAEQERRREQERLQAERE 732
Query: 369 LSRAAPDKRSKLQRNE-NRDISEVIALGVPNPRTSNEVQYDQRLFNQSKGMDSGFAGGED 427
L +K +LQ+ + R++ E + + + +R + + + A G
Sbjct: 733 LQER--EKALRLQKEQLQRELEE-------KKKKEEQQRLAERQLQEEQEKKAKEAAGAS 783
Query: 428 EIYNV---YDQAWRGGKDMAQSIYRPSKNLDKDMYGDDLEARIKTN 470
+ NV M +R ++ D YG DL + T+
Sbjct: 784 KALNVTVDVQSPACTSYQMTPQGHRAPPKINPDNYGMDLNSDDSTD 829
Score = 41.2 bits (95), Expect = 0.002
Identities = 32/110 (29%), Positives = 55/110 (50%), Gaps = 20/110 (18%)
Query: 297 KAREAVEM-----RAQVERKMAQKEKEKHEEKLREMAQKARERRAGIKTHVE-----KED 346
+ARE VE + Q+E+K AQ +++ + K +A++ +++A K E K++
Sbjct: 579 QARERVEQMKEEKKKQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQE 638
Query: 347 GEAR-------ERDEIRHD---RRKERQHDRNLSRAAPDKRSKLQRNENR 386
EAR E +E RH ++K+ + L +AA KR QR + R
Sbjct: 639 EEARRLRWLQQEEEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQER 688
Score = 32.7 bits (73), Expect = 0.86
Identities = 37/169 (21%), Positives = 69/169 (40%), Gaps = 27/169 (15%)
Query: 201 EMQKDPMEPPRFKINKKIPRGPPSPPAPVMHSPSRKMTVKEQQEWKIPPCISNWKNAKGY 260
+M P PR + I R P P R ++ ++E + +
Sbjct: 503 QMLMTPTSAPRSVMKSFIKRNTPLRMDPKEKERQRLENLRRKEEAE---------QLRRQ 553
Query: 261 TIPLDKRLAADGRGLQTVHINENFAKLAEALYIADRKAREAVEMRAQVERKMAQKEKEKH 320
+ DKR R L+ V + +L + L +R + E + Q+E+K AQ +++
Sbjct: 554 KVEEDKR-----RRLEEVKLKRE-ERLRKVLQARERVEQMKEEKKKQIEQKFAQIDEKTE 607
Query: 321 EEKLREMAQKARERRAGIKTHVEKEDGEARERDEIRHDRRKERQHDRNL 369
+ K +A++ +++A K + E+ EAR RK+ + R L
Sbjct: 608 KAKEERLAEEKAKKKAAAK---KMEEVEAR---------RKQEEEARRL 644
>gi|115298682 HBxAg transactivated protein 2 [Homo sapiens]
Length = 2817
Score = 43.5 bits (101), Expect = 5e-04
Identities = 56/270 (20%), Positives = 108/270 (40%), Gaps = 23/270 (8%)
Query: 123 EVMNADDPDLQRPDEEAIKEITEKTRVALEKSVSQKVAAAMPVRAADKLAPAQYIRYTPS 182
E +N D D Q + ++ A E + ++K + + PAQ PS
Sbjct: 330 EQLNFSDDDEQGSNSPKENNSEDQGSKASENNENKKETDEVSNTKSSSQIPAQ-----PS 384
Query: 183 QQGVAFNSGAKQRVIRMVEMQKDPMEPPRFKINKKIPRGPPSPPAPVMHSPSRKMTVKEQ 242
V + G R P PP+ + P + P PS++ E
Sbjct: 385 VAKVPYGKGPSFNQERGTSSHLPP--PPKLLAQQHPPPDRQAVPGRPGPFPSKQQVADED 442
Query: 243 QEWKIPPCISNWKNAKGYTIPLD---KRLAADGRGLQTVH---INENFAKLAEALYIADR 296
+ WK + + ++ KR + R ++ E +L E L I ++
Sbjct: 443 EIWK-----QRRRQQSEISAAVERARKRREEEERRMEEQRKAACAEKLKRLDEKLGILEK 497
Query: 297 K-AREAVEMRAQVERKMAQKEKEKHEEKLREMA-QKARERRAGIKTHVEKEDGEARERDE 354
+ + E + R + + + +KE EK +E+ RE +K RER+ + +EKE + RE ++
Sbjct: 498 QPSPEEIREREREKEREREKELEKEQEQEREKEREKDRERQQEKEKELEKEQEKQREMEK 557
Query: 355 IRHDRRKERQHDRNLSRAAPDKRSKLQRNE 384
+R++E++ + + + K++ E
Sbjct: 558 ---ERKQEKEKELERQKEKEKELQKMKEQE 584
Score = 31.2 bits (69), Expect = 2.5
Identities = 20/91 (21%), Positives = 44/91 (48%), Gaps = 1/91 (1%)
Query: 297 KAREAVEMRAQVERKMAQKEKEKHEEKLREMAQKARERRAGIKTHVEKEDGEARERDEIR 356
K RE R Q + K +KE+EK E +E Q+ +E+ + EKE + +E+++
Sbjct: 529 KEREKDRERQQEKEKELEKEQEKQREMEKERKQE-KEKELERQKEKEKELQKMKEQEKEC 587
Query: 357 HDRRKERQHDRNLSRAAPDKRSKLQRNENRD 387
++ + + + P+ +++ E+ +
Sbjct: 588 ELEKEREKLEEKIEPREPNLEPMVEKQESEN 618
Score = 30.0 bits (66), Expect = 5.5
Identities = 24/95 (25%), Positives = 45/95 (47%), Gaps = 5/95 (5%)
Query: 295 DRKAREAVEMRAQVER-KMAQKEKEKHEEKLREMA-QKARERRAGIKTHVEKEDGEARER 352
DR+ ++ E + E+ K + EKE+ +EK +E+ QK +E+ EKE +ER
Sbjct: 534 DRERQQEKEKELEKEQEKQREMEKERKQEKEKELERQKEKEKELQKMKEQEKECELEKER 593
Query: 353 DEIRHDRRKERQHDRNLSRAAPDKRSKLQRNENRD 387
+++ K + NL + S+ N+ +
Sbjct: 594 EKL---EEKIEPREPNLEPMVEKQESENSCNKEEE 625
Score = 29.6 bits (65), Expect = 7.2
Identities = 20/86 (23%), Positives = 42/86 (48%), Gaps = 8/86 (9%)
Query: 299 REAVEMRAQVERKMAQKEKEKHEEKLREMAQKARERRAGIKTHVEKEDGEARERDEIRHD 358
RE + + ++ +KE EK +EK REM ++ ++ + EKE +E+++
Sbjct: 527 REKEREKDRERQQEKEKELEKEQEKQREMEKERKQEK-------EKELERQKEKEK-ELQ 578
Query: 359 RRKERQHDRNLSRAAPDKRSKLQRNE 384
+ KE++ + L + K++ E
Sbjct: 579 KMKEQEKECELEKEREKLEEKIEPRE 604
>gi|193788632 DnaJ (Hsp40) homolog, subfamily C, member 2 isoform 2
[Homo sapiens]
Length = 568
Score = 43.1 bits (100), Expect = 6e-04
Identities = 29/89 (32%), Positives = 45/89 (50%), Gaps = 3/89 (3%)
Query: 294 ADRKAREAVEMRAQVERKMAQKEKEKHEEKLREMAQKARERRAGIKTHVEKEDGEARER- 352
A RK +EA E + Q E + A+ KEK EE++R+ A A++ + K ++KE + R
Sbjct: 301 AKRKEQEAKEKQRQAELEAARLAKEKEEEEVRQQALLAKKEKDIQKKAIKKERQKLRNSC 360
Query: 353 --DEIRHDRRKERQHDRNLSRAAPDKRSK 379
+EI RKE++ R A K
Sbjct: 361 KIEEINEQIRKEKEEAEARMRQASKNTEK 389
Score = 33.9 bits (76), Expect = 0.38
Identities = 33/139 (23%), Positives = 57/139 (41%), Gaps = 7/139 (5%)
Query: 294 ADRKAREAVEMRAQVERKMA---QKEKEKHEEKLREMAQKARERRAGIKTHVEKEDGEAR 350
A RK E +R V+ + + +K K EEK ++ A+K + A K KE
Sbjct: 256 AQRKKEEMNRIRTLVDNAYSCDPRIKKFKEEEKAKKEAEKKAKAEAKRKEQEAKEKQRQA 315
Query: 351 ERDEIRHDRRKERQHDRN---LSRAAPDKRSKLQRNENRDISEVIALGVPNPRTSNE-VQ 406
E + R + KE + R L++ D + K + E + + + N + E +
Sbjct: 316 ELEAARLAKEKEEEEVRQQALLAKKEKDIQKKAIKKERQKLRNSCKIEEINEQIRKEKEE 375
Query: 407 YDQRLFNQSKGMDSGFAGG 425
+ R+ SK + GG
Sbjct: 376 AEARMRQASKNTEKSTGGG 394
Score = 30.8 bits (68), Expect = 3.3
Identities = 27/116 (23%), Positives = 51/116 (43%), Gaps = 8/116 (6%)
Query: 249 PCISNWKNAKGYTIPLDKRLAADGRGLQTVHINENFAKLAEALYIADRKAREAVEMRAQV 308
P I +K + +K+ A+ + + E K +A A R A+E E +
Sbjct: 278 PRIKKFKEEEKAKKEAEKKAKAEAKRKE----QEAKEKQRQAELEAARLAKEKEEEEVRQ 333
Query: 309 ERKMAQKEKEKHEEKLREMAQKARE----RRAGIKTHVEKEDGEARERDEIRHDRR 360
+ +A+KEK+ ++ +++ QK R + EKE+ EAR R ++ +
Sbjct: 334 QALLAKKEKDIQKKAIKKERQKLRNSCKIEEINEQIRKEKEEAEARMRQASKNTEK 389
>gi|154146223 splicing factor, arginine/serine-rich 130 [Homo
sapiens]
Length = 805
Score = 43.1 bits (100), Expect = 6e-04
Identities = 55/243 (22%), Positives = 90/243 (37%), Gaps = 32/243 (13%)
Query: 310 RKMAQKEKEKHEEKLREMAQKARERRAGIKTHVEKEDGEARE--RDEIRHDRRK-ERQHD 366
R + K K++H + R R ++ E AR RD R +R ER+
Sbjct: 548 RSSSPKRKKRHSRSRSPTIKARRSRSRSYSRRIKIESNRARVKIRDRRRSNRNSIERERR 607
Query: 367 RNLSRAAPDKRSKLQRNENRDISEVIALGVPNPRTSNEVQYDQRLFNQSKGMDSGFAGGE 426
RN S + +RS+ + + R R S D+R + +G SG
Sbjct: 608 RNRSPSRERRRSRSRSRDRR-----------TNRASRSRSRDRRKIDDQRGNLSG----N 652
Query: 427 DEIYNVYDQAWRGGKDMAQSIYRPSKNLDKDMYGDDLEARIKTNRFVPDKEFSG-SDRRQ 485
+ + K+ ++SI + K DK+ + + + K R D +FS DR +
Sbjct: 653 SHKHKGEAKEQERKKERSRSIDKDRKKKDKEREREQDKRKEKQKREEKDFKFSSQDDRLK 712
Query: 486 RGREGPVQFEEDPFGLDKFL-------------EEAKQHGGSKRPSDSSRPKEHEHEGKK 532
R RE F K + +++K+H GS SS + KK
Sbjct: 713 RKRESERTFSRSGSISVKIIRHDSRQDSKKSTTKDSKKHSGSDSSGRSSSESPGSSKEKK 772
Query: 533 RRK 535
+K
Sbjct: 773 AKK 775
Score = 35.8 bits (81), Expect = 0.10
Identities = 24/108 (22%), Positives = 50/108 (46%), Gaps = 9/108 (8%)
Query: 295 DRKAREAVEMRAQVERKMAQKE------KEKHEEKLREMAQKARERRAGIKTHVEKEDGE 348
DR+ A R++ RK+ + KH+ + +E +K R+ K +K+
Sbjct: 625 DRRTNRASRSRSRDRRKIDDQRGNLSGNSHKHKGEAKEQERKKERSRSIDKDRKKKDKER 684
Query: 349 ARERDEIRHDRRKERQHDRNLSRAAPDKRSKLQRNENRDISEVIALGV 396
RE+D+ + K+++ +++ ++ D R K +R R S ++ V
Sbjct: 685 EREQDK---RKEKQKREEKDFKFSSQDDRLKRKRESERTFSRSGSISV 729
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.312 0.130 0.370
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 22,109,012
Number of Sequences: 37866
Number of extensions: 1119339
Number of successful extensions: 10488
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 187
Number of HSP's successfully gapped in prelim test: 415
Number of HSP's that attempted gapping in prelim test: 6340
Number of HSP's gapped (non-prelim): 2613
length of query: 536
length of database: 18,247,518
effective HSP length: 107
effective length of query: 429
effective length of database: 14,195,856
effective search space: 6090022224
effective search space used: 6090022224
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.