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Search of human proteins with 6912602
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|6912602 ADP-ribosylation factor interacting protein 2 [Homo
sapiens]
(341 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|6912602 ADP-ribosylation factor interacting protein 2 [Homo s... 678 0.0
gi|71040092 ADP-ribosylation factor interacting protein 1 isofor... 414 e-116
gi|7657210 ADP-ribosylation factor interacting protein 1 isoform... 414 e-116
gi|71040094 ADP-ribosylation factor interacting protein 1 isofor... 399 e-111
gi|88758603 protein interacting with C kinase 1 [Homo sapiens] 63 4e-10
gi|88758600 protein interacting with C kinase 1 [Homo sapiens] 63 4e-10
gi|7110697 protein interacting with C kinase 1 [Homo sapiens] 63 4e-10
gi|22095388 islet cell autoantigen 1,69kDa-like isoform 1 [Homo ... 44 2e-04
gi|209862841 islet cell autoantigen 1 [Homo sapiens] 39 0.007
gi|94721350 islet cell autoantigen 1 [Homo sapiens] 39 0.007
gi|12545395 islet cell autoantigen 1 [Homo sapiens] 39 0.007
gi|150418009 transforming, acidic coiled-coil containing protein... 37 0.033
gi|7657138 golgi integral membrane protein 4 [Homo sapiens] 36 0.043
gi|239757810 PREDICTED: similar to protein phosphatase 1, regula... 36 0.057
gi|58761532 protein phosphatase 1, regulatory (inhibitor) subuni... 36 0.057
gi|93102371 polybromo 1 isoform 2 [Homo sapiens] 36 0.057
gi|50897852 coiled-coil domain containing 88A isoform 2 [Homo sa... 35 0.074
gi|208022632 coiled-coil domain containing 88A isoform 1 [Homo s... 35 0.074
gi|115334682 SNAP25-interacting protein [Homo sapiens] 35 0.13
gi|114688046 TBC1 domain family, member 4 [Homo sapiens] 34 0.22
gi|4885399 structural maintenance of chromosomes 3 [Homo sapiens] 33 0.28
gi|55770888 early endosome antigen 1, 162kD [Homo sapiens] 33 0.28
gi|30794372 polybromo 1 isoform 1 [Homo sapiens] 33 0.48
gi|41281917 polybromo 1 isoform 4 [Homo sapiens] 33 0.48
gi|239756953 PREDICTED: hypothetical protein XP_002345113 [Homo ... 32 0.63
gi|239751432 PREDICTED: hypothetical protein XP_002347870 [Homo ... 32 0.63
gi|239745936 PREDICTED: hypothetical protein XP_002343581 [Homo ... 32 0.63
gi|118130809 endothelial cell-specific chemotaxis regulator [Hom... 32 1.1
gi|31559829 keratin 25 [Homo sapiens] 31 1.4
gi|5032173 nuclear receptor subfamily 2, group F, member 1 [Homo... 31 1.4
>gi|6912602 ADP-ribosylation factor interacting protein 2 [Homo
sapiens]
Length = 341
Score = 678 bits (1750), Expect = 0.0
Identities = 341/341 (100%), Positives = 341/341 (100%)
Query: 1 MTDGILGKAATMEIPIHGNGEARQLPEDDGLEQDLQQVMVSGPNLNETSIVSGGYGGSGD 60
MTDGILGKAATMEIPIHGNGEARQLPEDDGLEQDLQQVMVSGPNLNETSIVSGGYGGSGD
Sbjct: 1 MTDGILGKAATMEIPIHGNGEARQLPEDDGLEQDLQQVMVSGPNLNETSIVSGGYGGSGD 60
Query: 61 GLIPTGSGRHPSHSTTPSGPGDEVARGIAGEKFDIVKKWGINTYKCTKQLLSERFGRGSR 120
GLIPTGSGRHPSHSTTPSGPGDEVARGIAGEKFDIVKKWGINTYKCTKQLLSERFGRGSR
Sbjct: 61 GLIPTGSGRHPSHSTTPSGPGDEVARGIAGEKFDIVKKWGINTYKCTKQLLSERFGRGSR 120
Query: 121 TVDLELELQIELLRETKRKYESVLQLGRALTAHLYSLLQTQHALGDAFADLSQKSPELQE 180
TVDLELELQIELLRETKRKYESVLQLGRALTAHLYSLLQTQHALGDAFADLSQKSPELQE
Sbjct: 121 TVDLELELQIELLRETKRKYESVLQLGRALTAHLYSLLQTQHALGDAFADLSQKSPELQE 180
Query: 181 EFGYNAETQKLLCKNGETLLGAVNFFVSSINTLVTKTMEDTLMTVKQYEAARLEYDAYRT 240
EFGYNAETQKLLCKNGETLLGAVNFFVSSINTLVTKTMEDTLMTVKQYEAARLEYDAYRT
Sbjct: 181 EFGYNAETQKLLCKNGETLLGAVNFFVSSINTLVTKTMEDTLMTVKQYEAARLEYDAYRT 240
Query: 241 DLEELSLGPRDAGTRGRLESAQATFQAHRDKYEKLRGDVAIKLKFLEENKIKVMHKQLLL 300
DLEELSLGPRDAGTRGRLESAQATFQAHRDKYEKLRGDVAIKLKFLEENKIKVMHKQLLL
Sbjct: 241 DLEELSLGPRDAGTRGRLESAQATFQAHRDKYEKLRGDVAIKLKFLEENKIKVMHKQLLL 300
Query: 301 FHNAVSAYFAGNQKQLEQTLQQFNIKLRPPGAEKPSWLEEQ 341
FHNAVSAYFAGNQKQLEQTLQQFNIKLRPPGAEKPSWLEEQ
Sbjct: 301 FHNAVSAYFAGNQKQLEQTLQQFNIKLRPPGAEKPSWLEEQ 341
>gi|71040092 ADP-ribosylation factor interacting protein 1 isoform 2
[Homo sapiens]
Length = 341
Score = 414 bits (1065), Expect = e-116
Identities = 203/337 (60%), Positives = 265/337 (78%), Gaps = 5/337 (1%)
Query: 8 KAATMEIPIHGNGEARQLPEDDGLEQDLQQVMVSGPNLNETSIVSGGYGGSGDGLIPTGS 67
K + EIP+ NGE E +DL+ + SG L+ET I S G+ + +G+I G+
Sbjct: 7 KNSAAEIPVTSNGEVDDSREHS-FNRDLKHSLPSGLGLSETQITSHGFDNTKEGVIEAGA 65
Query: 68 GRHPSHSTTPSGP---GDEVARGIAGEKFDIVKKWGINTYKCTKQLLSERFGRGSRTVDL 124
+ + T SGP DE+ + A EK ++V+KW +NTYKCT+Q++SE+ GRGSRTVDL
Sbjct: 66 FQGGQRTQTKSGPVILADEI-KNPAMEKLELVRKWSLNTYKCTRQIISEKLGRGSRTVDL 124
Query: 125 ELELQIELLRETKRKYESVLQLGRALTAHLYSLLQTQHALGDAFADLSQKSPELQEEFGY 184
ELE QI++LR+ K+KYE++L+L + L+ L+ ++ TQ LGDAFADLS KS EL EEFGY
Sbjct: 125 ELEAQIDILRDNKKKYENILKLAQTLSTQLFQMVHTQRQLGDAFADLSLKSLELHEEFGY 184
Query: 185 NAETQKLLCKNGETLLGAVNFFVSSINTLVTKTMEDTLMTVKQYEAARLEYDAYRTDLEE 244
NA+TQKLL KNGETLLGA+NFF++S+NTLV KT+EDTLMTVKQYE+AR+EYDAYRTDLEE
Sbjct: 185 NADTQKLLAKNGETLLGAINFFIASVNTLVNKTIEDTLMTVKQYESARIEYDAYRTDLEE 244
Query: 245 LSLGPRDAGTRGRLESAQATFQAHRDKYEKLRGDVAIKLKFLEENKIKVMHKQLLLFHNA 304
L+LGPRDA T ++E +Q FQAH++KY+K+R DV++KLKFLEENK+KV+H QL+LFHNA
Sbjct: 245 LNLGPRDANTLPKIEQSQHLFQAHKEKYDKMRNDVSVKLKFLEENKVKVLHNQLVLFHNA 304
Query: 305 VSAYFAGNQKQLEQTLQQFNIKLRPPGAEKPSWLEEQ 341
++AYFAGNQKQLEQTL+QF+IKL+ PG + PSWLEEQ
Sbjct: 305 IAAYFAGNQKQLEQTLKQFHIKLKTPGVDAPSWLEEQ 341
>gi|7657210 ADP-ribosylation factor interacting protein 1 isoform 2
[Homo sapiens]
Length = 341
Score = 414 bits (1065), Expect = e-116
Identities = 203/337 (60%), Positives = 265/337 (78%), Gaps = 5/337 (1%)
Query: 8 KAATMEIPIHGNGEARQLPEDDGLEQDLQQVMVSGPNLNETSIVSGGYGGSGDGLIPTGS 67
K + EIP+ NGE E +DL+ + SG L+ET I S G+ + +G+I G+
Sbjct: 7 KNSAAEIPVTSNGEVDDSREHS-FNRDLKHSLPSGLGLSETQITSHGFDNTKEGVIEAGA 65
Query: 68 GRHPSHSTTPSGP---GDEVARGIAGEKFDIVKKWGINTYKCTKQLLSERFGRGSRTVDL 124
+ + T SGP DE+ + A EK ++V+KW +NTYKCT+Q++SE+ GRGSRTVDL
Sbjct: 66 FQGGQRTQTKSGPVILADEI-KNPAMEKLELVRKWSLNTYKCTRQIISEKLGRGSRTVDL 124
Query: 125 ELELQIELLRETKRKYESVLQLGRALTAHLYSLLQTQHALGDAFADLSQKSPELQEEFGY 184
ELE QI++LR+ K+KYE++L+L + L+ L+ ++ TQ LGDAFADLS KS EL EEFGY
Sbjct: 125 ELEAQIDILRDNKKKYENILKLAQTLSTQLFQMVHTQRQLGDAFADLSLKSLELHEEFGY 184
Query: 185 NAETQKLLCKNGETLLGAVNFFVSSINTLVTKTMEDTLMTVKQYEAARLEYDAYRTDLEE 244
NA+TQKLL KNGETLLGA+NFF++S+NTLV KT+EDTLMTVKQYE+AR+EYDAYRTDLEE
Sbjct: 185 NADTQKLLAKNGETLLGAINFFIASVNTLVNKTIEDTLMTVKQYESARIEYDAYRTDLEE 244
Query: 245 LSLGPRDAGTRGRLESAQATFQAHRDKYEKLRGDVAIKLKFLEENKIKVMHKQLLLFHNA 304
L+LGPRDA T ++E +Q FQAH++KY+K+R DV++KLKFLEENK+KV+H QL+LFHNA
Sbjct: 245 LNLGPRDANTLPKIEQSQHLFQAHKEKYDKMRNDVSVKLKFLEENKVKVLHNQLVLFHNA 304
Query: 305 VSAYFAGNQKQLEQTLQQFNIKLRPPGAEKPSWLEEQ 341
++AYFAGNQKQLEQTL+QF+IKL+ PG + PSWLEEQ
Sbjct: 305 IAAYFAGNQKQLEQTLKQFHIKLKTPGVDAPSWLEEQ 341
>gi|71040094 ADP-ribosylation factor interacting protein 1 isoform 1
[Homo sapiens]
Length = 373
Score = 399 bits (1026), Expect = e-111
Identities = 206/369 (55%), Positives = 266/369 (72%), Gaps = 37/369 (10%)
Query: 8 KAATMEIPIHGNGEARQLPEDDGLEQDLQQVMVSGPNLNETSIVSGGYGGSGDGLIPTG- 66
K + EIP+ NGE E +DL+ + SG L+ET I S G+ + +G+I G
Sbjct: 7 KNSAAEIPVTSNGEVDDSREHS-FNRDLKHSLPSGLGLSETQITSHGFDNTKEGVIEAGA 65
Query: 67 ----------SGRHPSH---------------------STTPSGP---GDEVARGIAGEK 92
S PS + T SGP DE+ + A EK
Sbjct: 66 FQGSPAPPLPSVMSPSRVAASRLAQQGSDLIVPAGGQRTQTKSGPVILADEI-KNPAMEK 124
Query: 93 FDIVKKWGINTYKCTKQLLSERFGRGSRTVDLELELQIELLRETKRKYESVLQLGRALTA 152
++V+KW +NTYKCT+Q++SE+ GRGSRTVDLELE QI++LR+ K+KYE++L+L + L+
Sbjct: 125 LELVRKWSLNTYKCTRQIISEKLGRGSRTVDLELEAQIDILRDNKKKYENILKLAQTLST 184
Query: 153 HLYSLLQTQHALGDAFADLSQKSPELQEEFGYNAETQKLLCKNGETLLGAVNFFVSSINT 212
L+ ++ TQ LGDAFADLS KS EL EEFGYNA+TQKLL KNGETLLGA+NFF++S+NT
Sbjct: 185 QLFQMVHTQRQLGDAFADLSLKSLELHEEFGYNADTQKLLAKNGETLLGAINFFIASVNT 244
Query: 213 LVTKTMEDTLMTVKQYEAARLEYDAYRTDLEELSLGPRDAGTRGRLESAQATFQAHRDKY 272
LV KT+EDTLMTVKQYE+AR+EYDAYRTDLEEL+LGPRDA T ++E +Q FQAH++KY
Sbjct: 245 LVNKTIEDTLMTVKQYESARIEYDAYRTDLEELNLGPRDANTLPKIEQSQHLFQAHKEKY 304
Query: 273 EKLRGDVAIKLKFLEENKIKVMHKQLLLFHNAVSAYFAGNQKQLEQTLQQFNIKLRPPGA 332
+K+R DV++KLKFLEENK+KV+H QL+LFHNA++AYFAGNQKQLEQTL+QF+IKL+ PG
Sbjct: 305 DKMRNDVSVKLKFLEENKVKVLHNQLVLFHNAIAAYFAGNQKQLEQTLKQFHIKLKTPGV 364
Query: 333 EKPSWLEEQ 341
+ PSWLEEQ
Sbjct: 365 DAPSWLEEQ 373
>gi|88758603 protein interacting with C kinase 1 [Homo sapiens]
Length = 415
Score = 62.8 bits (151), Expect = 4e-10
Identities = 49/194 (25%), Positives = 92/194 (47%), Gaps = 13/194 (6%)
Query: 129 QIELLRETKRKYESVLQLGRALTAHLYSLLQTQHALGDAFADLSQKSPE--LQEEFGYNA 186
++E L T Y+ + + + L Y L QT A GD F+ + + P+ E F A
Sbjct: 152 RLEELERTAELYKGMTEHTKNLLRAFYELSQTHRAFGDVFSVIGVREPQPAASEAFVKFA 211
Query: 187 ETQKLLCKNGETLLGAVNFFVSSINTLVTKTMEDTLMTVKQYEAARLEYDAYRTDLEE-- 244
+ + + K G LL + ++ +NT + K + DT +T+K+Y + EY +Y ++E
Sbjct: 212 DAHRSIEKFGIRLLKTIKPMLTDLNTYLNKAIPDTRLTIKKYLDVKFEYLSYCLKVKEMD 271
Query: 245 ------LSLG-PRDAGTRGRLE--SAQATFQAHRDKYEKLRGDVAIKLKFLEENKIKVMH 295
++LG P + G E Q R ++ ++R DV K++ L++ ++ +
Sbjct: 272 DEEYSCIALGEPLYRVSTGNYEYRLILRCRQEARARFSQMRKDVLEKMELLDQKHVQDIV 331
Query: 296 KQLLLFHNAVSAYF 309
QL + +S Y+
Sbjct: 332 FQLQRLVSTMSKYY 345
>gi|88758600 protein interacting with C kinase 1 [Homo sapiens]
Length = 415
Score = 62.8 bits (151), Expect = 4e-10
Identities = 49/194 (25%), Positives = 92/194 (47%), Gaps = 13/194 (6%)
Query: 129 QIELLRETKRKYESVLQLGRALTAHLYSLLQTQHALGDAFADLSQKSPE--LQEEFGYNA 186
++E L T Y+ + + + L Y L QT A GD F+ + + P+ E F A
Sbjct: 152 RLEELERTAELYKGMTEHTKNLLRAFYELSQTHRAFGDVFSVIGVREPQPAASEAFVKFA 211
Query: 187 ETQKLLCKNGETLLGAVNFFVSSINTLVTKTMEDTLMTVKQYEAARLEYDAYRTDLEE-- 244
+ + + K G LL + ++ +NT + K + DT +T+K+Y + EY +Y ++E
Sbjct: 212 DAHRSIEKFGIRLLKTIKPMLTDLNTYLNKAIPDTRLTIKKYLDVKFEYLSYCLKVKEMD 271
Query: 245 ------LSLG-PRDAGTRGRLE--SAQATFQAHRDKYEKLRGDVAIKLKFLEENKIKVMH 295
++LG P + G E Q R ++ ++R DV K++ L++ ++ +
Sbjct: 272 DEEYSCIALGEPLYRVSTGNYEYRLILRCRQEARARFSQMRKDVLEKMELLDQKHVQDIV 331
Query: 296 KQLLLFHNAVSAYF 309
QL + +S Y+
Sbjct: 332 FQLQRLVSTMSKYY 345
>gi|7110697 protein interacting with C kinase 1 [Homo sapiens]
Length = 415
Score = 62.8 bits (151), Expect = 4e-10
Identities = 49/194 (25%), Positives = 92/194 (47%), Gaps = 13/194 (6%)
Query: 129 QIELLRETKRKYESVLQLGRALTAHLYSLLQTQHALGDAFADLSQKSPE--LQEEFGYNA 186
++E L T Y+ + + + L Y L QT A GD F+ + + P+ E F A
Sbjct: 152 RLEELERTAELYKGMTEHTKNLLRAFYELSQTHRAFGDVFSVIGVREPQPAASEAFVKFA 211
Query: 187 ETQKLLCKNGETLLGAVNFFVSSINTLVTKTMEDTLMTVKQYEAARLEYDAYRTDLEE-- 244
+ + + K G LL + ++ +NT + K + DT +T+K+Y + EY +Y ++E
Sbjct: 212 DAHRSIEKFGIRLLKTIKPMLTDLNTYLNKAIPDTRLTIKKYLDVKFEYLSYCLKVKEMD 271
Query: 245 ------LSLG-PRDAGTRGRLE--SAQATFQAHRDKYEKLRGDVAIKLKFLEENKIKVMH 295
++LG P + G E Q R ++ ++R DV K++ L++ ++ +
Sbjct: 272 DEEYSCIALGEPLYRVSTGNYEYRLILRCRQEARARFSQMRKDVLEKMELLDQKHVQDIV 331
Query: 296 KQLLLFHNAVSAYF 309
QL + +S Y+
Sbjct: 332 FQLQRLVSTMSKYY 345
>gi|22095388 islet cell autoantigen 1,69kDa-like isoform 1 [Homo
sapiens]
Length = 482
Score = 43.9 bits (102), Expect = 2e-04
Identities = 39/201 (19%), Positives = 83/201 (41%), Gaps = 7/201 (3%)
Query: 123 DLELELQIELLRETKRKYESVLQLGRALTAHLYSLLQTQHALGDAFADLSQKSPELQEEF 182
D EL+ ++E+ + +L++ L + + ++ LG F + Q
Sbjct: 46 DAELDAKLEVFHSVQETCTELLKIIEKYQLRLNVISEEENELG-LFLKFQAERDATQAGK 104
Query: 183 GYNAETQKLLCKNGETLLGA---VNFFVSSINTLVTKTMEDTLMTVKQYEAARLEYDAYR 239
+A T K LC + + L ++ + T + + DTLMT+ + E AR EY
Sbjct: 105 MMDA-TGKALCSSAKQRLALCTPLSRLKQEVATFSQRAVSDTLMTINRMEQARTEYRGAL 163
Query: 240 TDLEELS--LGPRDAGTRGRLESAQATFQAHRDKYEKLRGDVAIKLKFLEENKIKVMHKQ 297
++++S L P + Q + + ++KL+ DV K+ L ++ ++
Sbjct: 164 LWMKDVSQELDPDTLKQMEKFRKVQMQVRNSKASFDKLKMDVCQKVDLLGASRCNMLSHS 223
Query: 298 LLLFHNAVSAYFAGNQKQLEQ 318
L + + ++ + + Q
Sbjct: 224 LTTYQRTLLGFWKKTARMMSQ 244
>gi|209862841 islet cell autoantigen 1 [Homo sapiens]
Length = 483
Score = 38.9 bits (89), Expect = 0.007
Identities = 42/196 (21%), Positives = 81/196 (41%), Gaps = 23/196 (11%)
Query: 123 DLELELQIELLRETKRKYESVLQLGRALTAH---LYSLLQTQHALG-----DAFADLSQK 174
D +L+ ++EL +R + L L +A+ + + L Q ++ LG F D ++
Sbjct: 53 DADLDAKLELFHSIQR---TCLDLSKAIVLYQKRICFLSQEENELGKFLRSQGFQDKTRA 109
Query: 175 SPELQEEFGYNAETQKLLCKNGETLLGAVN---FFVSSINTLVTKTMEDTLMTVKQYEAA 231
+Q T K LC + + L N F + T + + DT +TV + E
Sbjct: 110 GKMMQA-------TGKALCFSSQQRLALRNPLCRFHQEVETFRHRAISDTWLTVNRMEQC 162
Query: 232 RLEYDAYRTDLEELS--LGPRDAGTRGRLESAQATFQAHRDKYEKLRGDVAIKLKFLEEN 289
R EY ++++S L P + Q + + ++KL+ DV K+ L +
Sbjct: 163 RTEYRGALLWMKDVSQELDPDLYKQMEKFRKVQTQVRLAKKNFDKLKMDVCQKVDLLGAS 222
Query: 290 KIKVMHKQLLLFHNAV 305
+ ++ L + +
Sbjct: 223 RCNLLSHMLATYQTTL 238
>gi|94721350 islet cell autoantigen 1 [Homo sapiens]
Length = 483
Score = 38.9 bits (89), Expect = 0.007
Identities = 42/196 (21%), Positives = 81/196 (41%), Gaps = 23/196 (11%)
Query: 123 DLELELQIELLRETKRKYESVLQLGRALTAH---LYSLLQTQHALG-----DAFADLSQK 174
D +L+ ++EL +R + L L +A+ + + L Q ++ LG F D ++
Sbjct: 53 DADLDAKLELFHSIQR---TCLDLSKAIVLYQKRICFLSQEENELGKFLRSQGFQDKTRA 109
Query: 175 SPELQEEFGYNAETQKLLCKNGETLLGAVN---FFVSSINTLVTKTMEDTLMTVKQYEAA 231
+Q T K LC + + L N F + T + + DT +TV + E
Sbjct: 110 GKMMQA-------TGKALCFSSQQRLALRNPLCRFHQEVETFRHRAISDTWLTVNRMEQC 162
Query: 232 RLEYDAYRTDLEELS--LGPRDAGTRGRLESAQATFQAHRDKYEKLRGDVAIKLKFLEEN 289
R EY ++++S L P + Q + + ++KL+ DV K+ L +
Sbjct: 163 RTEYRGALLWMKDVSQELDPDLYKQMEKFRKVQTQVRLAKKNFDKLKMDVCQKVDLLGAS 222
Query: 290 KIKVMHKQLLLFHNAV 305
+ ++ L + +
Sbjct: 223 RCNLLSHMLATYQTTL 238
>gi|12545395 islet cell autoantigen 1 [Homo sapiens]
Length = 483
Score = 38.9 bits (89), Expect = 0.007
Identities = 42/196 (21%), Positives = 81/196 (41%), Gaps = 23/196 (11%)
Query: 123 DLELELQIELLRETKRKYESVLQLGRALTAH---LYSLLQTQHALG-----DAFADLSQK 174
D +L+ ++EL +R + L L +A+ + + L Q ++ LG F D ++
Sbjct: 53 DADLDAKLELFHSIQR---TCLDLSKAIVLYQKRICFLSQEENELGKFLRSQGFQDKTRA 109
Query: 175 SPELQEEFGYNAETQKLLCKNGETLLGAVN---FFVSSINTLVTKTMEDTLMTVKQYEAA 231
+Q T K LC + + L N F + T + + DT +TV + E
Sbjct: 110 GKMMQA-------TGKALCFSSQQRLALRNPLCRFHQEVETFRHRAISDTWLTVNRMEQC 162
Query: 232 RLEYDAYRTDLEELS--LGPRDAGTRGRLESAQATFQAHRDKYEKLRGDVAIKLKFLEEN 289
R EY ++++S L P + Q + + ++KL+ DV K+ L +
Sbjct: 163 RTEYRGALLWMKDVSQELDPDLYKQMEKFRKVQTQVRLAKKNFDKLKMDVCQKVDLLGAS 222
Query: 290 KIKVMHKQLLLFHNAV 305
+ ++ L + +
Sbjct: 223 RCNLLSHMLATYQTTL 238
>gi|150418009 transforming, acidic coiled-coil containing protein 2
isoform a [Homo sapiens]
Length = 2948
Score = 36.6 bits (83), Expect = 0.033
Identities = 26/85 (30%), Positives = 33/85 (38%), Gaps = 1/85 (1%)
Query: 1 MTDGILGKAATMEIPIHGNGEARQLPEDDGLEQDLQQVMVSGPNLNETSIVSGGYGGSGD 60
+ G+ AAT E+P+ + P G E Q + SG ETS +G G
Sbjct: 1556 LASGLPSPAATQELPVERAAAFQVAPHSHGEEAVAQDRIPSGKQHQETSACDSPHGEDGP 1615
Query: 61 G-LIPTGSGRHPSHSTTPSGPGDEV 84
G TG H ST P EV
Sbjct: 1616 GDFAHTGVPGHVPRSTCAPSPQREV 1640
>gi|7657138 golgi integral membrane protein 4 [Homo sapiens]
Length = 696
Score = 36.2 bits (82), Expect = 0.043
Identities = 63/252 (25%), Positives = 98/252 (38%), Gaps = 47/252 (18%)
Query: 134 RETKRKYESVLQL----GRALTAHLYSLLQTQHALGDAFADLSQK-----SPELQEEFGY 184
R+ KR ++++L L G A LY LQTQ +A A Q+ S +LQ + +
Sbjct: 8 RKQKRIFQTLLLLTVVFGFLYGAMLYYELQTQLRKAEAVALKYQQHQESLSAQLQVVYEH 67
Query: 185 NAETQKLLCKNG-ETLLGAVNFFVSSINTLVT--KTMEDTLMTVKQYEAARLEYDAYRTD 241
+ +K L K E +F V + T K +D+ +Y A +++ ++
Sbjct: 68 RSRLEKSLQKERLEHKKAKEDFLVYKLEAQETLNKGRQDSN---SRYSALNVQHQMLKSQ 124
Query: 242 LEELSLGPRDAGTRGRL--ESAQATFQAHRDKYEKLRGDVAIKLKFL--------EENK- 290
EEL D R E TF H+ KY +L+ + +L L EEN+
Sbjct: 125 HEELKKQHSDLEEEHRKQGEDFSRTFNDHKQKYLQLQQEKEQELSKLKETVYNLREENRQ 184
Query: 291 --------------IKVMHKQLLLFHNAV-------SAYFAGNQKQLEQTLQQFNIKLRP 329
+K HK LL H + + A Q Q+ + Q + R
Sbjct: 185 LRKAHQDIHTQLQDVKQQHKNLLSEHEQLVVTLEDHKSALAAAQTQVAEYKQLKDTLNRI 244
Query: 330 PGAEKPSWLEEQ 341
P KP E+Q
Sbjct: 245 PSLRKPDPAEQQ 256
>gi|239757810 PREDICTED: similar to protein phosphatase 1,
regulatory (inhibitor) subunit 3F [Homo sapiens]
Length = 724
Score = 35.8 bits (81), Expect = 0.057
Identities = 31/122 (25%), Positives = 54/122 (44%), Gaps = 31/122 (25%)
Query: 22 ARQLPEDDGLEQDLQQVMVSGPNLNETSIVSGGYGGSGDGLIPTGSGRHPSHSTTPSGPG 81
+ +L +D ++Q+L+Q+ +S + ++ +GG GG G+G T G PSH
Sbjct: 475 SEELLGEDTIDQELEQLYLSHLSRLRAAVAAGGAGGGGEG--STDGGMSPSHPL------ 526
Query: 82 DEVARGIAGEKFDIVKKWGINTYKCTKQLLSE------RFGRGSRTVDLELELQIELLRE 135
GI ++ D++ KW L E R GRG +EL+++
Sbjct: 527 -----GILTDR-DLILKWPGPERALNSALAEEITLHYARLGRG-----------VELIKD 569
Query: 136 TK 137
T+
Sbjct: 570 TE 571
>gi|58761532 protein phosphatase 1, regulatory (inhibitor) subunit
3F [Homo sapiens]
Length = 799
Score = 35.8 bits (81), Expect = 0.057
Identities = 31/122 (25%), Positives = 54/122 (44%), Gaps = 31/122 (25%)
Query: 22 ARQLPEDDGLEQDLQQVMVSGPNLNETSIVSGGYGGSGDGLIPTGSGRHPSHSTTPSGPG 81
+ +L +D ++Q+L+Q+ +S + ++ +GG GG G+G T G PSH
Sbjct: 475 SEELLGEDTIDQELEQLYLSHLSRLRAAVAAGGAGGGGEG--STDGGMSPSHPL------ 526
Query: 82 DEVARGIAGEKFDIVKKWGINTYKCTKQLLSE------RFGRGSRTVDLELELQIELLRE 135
GI ++ D++ KW L E R GRG +EL+++
Sbjct: 527 -----GILTDR-DLILKWPGPERALNSALAEEITLHYARLGRG-----------VELIKD 569
Query: 136 TK 137
T+
Sbjct: 570 TE 571
>gi|93102371 polybromo 1 isoform 2 [Homo sapiens]
Length = 1582
Score = 35.8 bits (81), Expect = 0.057
Identities = 44/185 (23%), Positives = 81/185 (43%), Gaps = 36/185 (19%)
Query: 153 HLYSLLQTQHALGDAFADLSQKSPELQEEFGYNAETQKLLCKNGETLLG-AVNFFVSSIN 211
H++ +L+ + +++ + + ELQ+ F + + LCKNGE LL A+++ ++
Sbjct: 843 HMFEVLERARRMNRTDSEIYEDAVELQQFF---IKIRDELCKNGEILLSPALSYTTKHLH 899
Query: 212 TLVTKTMEDTLMTVKQYEAARLEYDAYRTDLEELSLGPRDAGTRG--------------- 256
V K ++ L K+ E +L+ + + + E+ AG G
Sbjct: 900 NDVEKERKEKL--PKEIEEDKLKREEEKREAEKSEDSSGAAGLSGLHRTYSQDCSFKNSM 957
Query: 257 -------RLESAQATFQAHRDKYEKLRGDVAIKLKFLEE--NKI---KVMHKQLLLFHNA 304
+E A+A Q H E+L D A K F + NK+ K++ K +++F
Sbjct: 958 YHVGDYVYVEPAEANLQPHIVCIERLWEDSAEKEVFKSDYYNKVPVSKILGKCVVMF--- 1014
Query: 305 VSAYF 309
V YF
Sbjct: 1015 VKEYF 1019
>gi|50897852 coiled-coil domain containing 88A isoform 2 [Homo
sapiens]
Length = 1843
Score = 35.4 bits (80), Expect = 0.074
Identities = 52/200 (26%), Positives = 82/200 (41%), Gaps = 33/200 (16%)
Query: 126 LELQIELLRETKRKYESVLQLGRALTAHLYSLLQTQHALGDAFADL----------SQKS 175
LE + L RK + L + LT L SL + L + +L S K
Sbjct: 661 LEQENSELERENRKLKKTLDSFKNLTFQLESLEKENSQLDEENLELRRNVESLKCASMKM 720
Query: 176 PELQEEFGYNAETQKLLCKNGETLLGA---------VNFFVSSI-NTLVTKTMEDTLMTV 225
+LQ E E++K K G LL A V++ I N + KT+E++ +
Sbjct: 721 AQLQLE-NKELESEKEQLKKGLELLKASFKKTERLEVSYQGLDIENQRLQKTLENSNKKI 779
Query: 226 KQYEAA----RLEYDAYRTDLEELSLGPR--DAGTRGRLESAQATFQAHRDKYE------ 273
+Q E+ +E + +LEEL + + + + Q T Q +DK +
Sbjct: 780 QQLESELQDLEMENQTLQKNLEELKISSKRLEQLEKENKSLEQETSQLEKDKKQLEKENK 839
Query: 274 KLRGDVAIKLKFLEENKIKV 293
+LR IK LEEN +K+
Sbjct: 840 RLRQQAEIKDTTLEENNVKI 859
>gi|208022632 coiled-coil domain containing 88A isoform 1 [Homo
sapiens]
Length = 1870
Score = 35.4 bits (80), Expect = 0.074
Identities = 52/200 (26%), Positives = 82/200 (41%), Gaps = 33/200 (16%)
Query: 126 LELQIELLRETKRKYESVLQLGRALTAHLYSLLQTQHALGDAFADL----------SQKS 175
LE + L RK + L + LT L SL + L + +L S K
Sbjct: 661 LEQENSELERENRKLKKTLDSFKNLTFQLESLEKENSQLDEENLELRRNVESLKCASMKM 720
Query: 176 PELQEEFGYNAETQKLLCKNGETLLGA---------VNFFVSSI-NTLVTKTMEDTLMTV 225
+LQ E E++K K G LL A V++ I N + KT+E++ +
Sbjct: 721 AQLQLE-NKELESEKEQLKKGLELLKASFKKTERLEVSYQGLDIENQRLQKTLENSNKKI 779
Query: 226 KQYEAA----RLEYDAYRTDLEELSLGPR--DAGTRGRLESAQATFQAHRDKYE------ 273
+Q E+ +E + +LEEL + + + + Q T Q +DK +
Sbjct: 780 QQLESELQDLEMENQTLQKNLEELKISSKRLEQLEKENKSLEQETSQLEKDKKQLEKENK 839
Query: 274 KLRGDVAIKLKFLEENKIKV 293
+LR IK LEEN +K+
Sbjct: 840 RLRQQAEIKDTTLEENNVKI 859
>gi|115334682 SNAP25-interacting protein [Homo sapiens]
Length = 1183
Score = 34.7 bits (78), Expect = 0.13
Identities = 44/194 (22%), Positives = 71/194 (36%), Gaps = 35/194 (18%)
Query: 30 GLEQDLQQVMVSGPNLNETSIVSGGYGGSGDGLIPTGSGRHPSHSTTPSGPGDEVA---- 85
G E + + G N T G GG G P PS S+TP+G V+
Sbjct: 591 GSEPETPSEKIEGSNGAATPSAPCGSGGRSSGATPVSGPPPPSASSTPAGQPTAVSRLQM 650
Query: 86 ----RGIAGEKFDI------VKKWGINTYKCTKQLLSERFGRGSRTVDLELELQIELLRE 135
RG+ D+ ++K + + + LL + + EL +++ E
Sbjct: 651 QLHLRGLQNSASDLRGQLQQLRKLQLQNQESVRALL--------KRTEAELSMRVS---E 699
Query: 136 TKRKYESVLQLGRALT-AHLYSLLQTQHALGDAFADLSQKSPELQEEFGYN--------A 186
R+ E LQ R L L + + DL + ++Q + +N
Sbjct: 700 AARRQEDPLQRQRTLVEEERLRYLNDEELITQQLNDLEKSVEKIQRDVSHNHRLVPGPEL 759
Query: 187 ETQKLLCKN-GETL 199
E + L+ K GETL
Sbjct: 760 EEKALVLKQLGETL 773
>gi|114688046 TBC1 domain family, member 4 [Homo sapiens]
Length = 1298
Score = 33.9 bits (76), Expect = 0.22
Identities = 30/109 (27%), Positives = 50/109 (45%), Gaps = 8/109 (7%)
Query: 188 TQKLLCKNGETLLGAVNFFVSSINTLVTKTMEDTLMTV------KQYEAARLEYDAYRTD 241
+Q+ L E+ V F +++ + T ME + V KQ A +EY + +
Sbjct: 1126 SQETLIMECESFENIVEFLKNTLPDMNTSEMEKIITQVFEMDISKQLHAYEVEYHVLQDE 1185
Query: 242 LEELSLGPRDAGTRGRLESAQATF-QAHRDKYEKLRGDVAIKLKFLEEN 289
L+E S D+ T +LE A + + + D EKL+ K++ LE N
Sbjct: 1186 LQESSYSCEDSETLEKLERANSQLKRQNMDLLEKLQ-VAHTKIQALESN 1233
>gi|4885399 structural maintenance of chromosomes 3 [Homo sapiens]
Length = 1217
Score = 33.5 bits (75), Expect = 0.28
Identities = 54/239 (22%), Positives = 94/239 (39%), Gaps = 33/239 (13%)
Query: 95 IVKKWGIN---TYKCTKQLLSERFGRGSRTVDLELELQIELLRETKRKYESVLQLGRALT 151
IVK+ IN T +++L R G+R D E I L++ET+ K E + +L + +
Sbjct: 138 IVKQGKINQMATAPDSQRLKLLREVAGTRVYDERKEESISLMKETEGKREKINELLKYIE 197
Query: 152 AHLYSLLQTQHALGDAFADLSQKSPELQEEFGYNAETQKLLCKNGETLLGAVNFFVSSIN 211
L++L + + L QK +++ Y Q+L N
Sbjct: 198 ERLHTLEEEKEELAQ-----YQKWDKMRRALEYTIYNQEL-------------------N 233
Query: 212 TLVTKTMEDTLMTVKQYEAARLEYDAY---RTDLEELSLGPRDAGTR-GRLESAQATFQA 267
K E + E +R DA R +E++ R+ T+ ++ + A
Sbjct: 234 ETRAKLDELSAKRETSGEKSRQLRDAQQDARDKMEDIERQVRELKTKISAMKEEKEQLSA 293
Query: 268 HRDKYEKLRGDVAIKLKFLEENKI--KVMHKQLLLFHNAVSAYFAGNQKQLEQTLQQFN 324
R + K R + +K K L++ K+LL + QK+L +T +FN
Sbjct: 294 ERQEQIKQRTKLELKAKDLQDELAGNSEQRKRLLKERQKLLEKIEEKQKELAETEPKFN 352
>gi|55770888 early endosome antigen 1, 162kD [Homo sapiens]
Length = 1411
Score = 33.5 bits (75), Expect = 0.28
Identities = 47/216 (21%), Positives = 86/216 (39%), Gaps = 23/216 (10%)
Query: 126 LELQIELLRETKRKYESVLQLGRALTAHLYSLLQTQHALGDAFADLSQKSPELQEEFGYN 185
L+ Q EL + +++ E+ QL L + L+Q Q+ L + Q + E +
Sbjct: 909 LKEQKELKKSLEKEKEASHQLKLELNSMQEQLIQAQNTLKQNEKEEQQLQGNINE-LKQS 967
Query: 186 AETQKLLCKNGETLLGAVNFFVSSINTLVTKTMEDTLMTVKQYEAARLEYDAYRTDLEEL 245
+E +K K E L G + V L K + ++ A + + + + E+
Sbjct: 968 SEQKK---KQIEALQGELKIAVLQKTELENKLQQQLTQAAQELAAEKEKISVLQNNYEK- 1023
Query: 246 SLGPRDAGTRGRLESAQATFQAHRDKYEKLRGDVAIKLKFLEENKIKVMHKQLLLFHNAV 305
++ + Q+ F + R D LK +EE K+ + + L+ N +
Sbjct: 1024 --------SQETFKQLQSDFYGRESELLATRQD----LKSVEE-KLSLAQEDLISNRNQI 1070
Query: 306 SAYFAGNQKQLEQTLQQFNIKLRPPGAEKPSWLEEQ 341
GNQ +L Q L+ L A+K L+E+
Sbjct: 1071 -----GNQNKLIQELKTAKATLEQDSAKKEQQLQER 1101
>gi|30794372 polybromo 1 isoform 1 [Homo sapiens]
Length = 1602
Score = 32.7 bits (73), Expect = 0.48
Identities = 25/105 (23%), Positives = 52/105 (49%), Gaps = 6/105 (5%)
Query: 153 HLYSLLQTQHALGDAFADLSQKSPELQEEFGYNAETQKLLCKNGETLLG-AVNFFVSSIN 211
H++ +L+ + +++ + + ELQ+ F + + LCKNGE LL A+++ ++
Sbjct: 811 HMFEVLERARRMNRTDSEIYEDAVELQQFF---IKIRDELCKNGEILLSPALSYTTKHLH 867
Query: 212 TLVTKTMEDTLMTVKQYEAARLEYDAYRTDLEELSLGPRDAGTRG 256
V K ++ L K+ E +L+ + + + E+ AG G
Sbjct: 868 NDVEKERKEKL--PKEIEEDKLKREEEKREAEKSEDSSGAAGLSG 910
>gi|41281917 polybromo 1 isoform 4 [Homo sapiens]
Length = 1582
Score = 32.7 bits (73), Expect = 0.48
Identities = 25/105 (23%), Positives = 52/105 (49%), Gaps = 6/105 (5%)
Query: 153 HLYSLLQTQHALGDAFADLSQKSPELQEEFGYNAETQKLLCKNGETLLG-AVNFFVSSIN 211
H++ +L+ + +++ + + ELQ+ F + + LCKNGE LL A+++ ++
Sbjct: 843 HMFEVLERARRMNRTDSEIYEDAVELQQFF---IKIRDELCKNGEILLSPALSYTTKHLH 899
Query: 212 TLVTKTMEDTLMTVKQYEAARLEYDAYRTDLEELSLGPRDAGTRG 256
V K ++ L K+ E +L+ + + + E+ AG G
Sbjct: 900 NDVEKERKEKL--PKEIEEDKLKREEEKREAEKSEDSSGAAGLSG 942
>gi|239756953 PREDICTED: hypothetical protein XP_002345113 [Homo
sapiens]
Length = 161
Score = 32.3 bits (72), Expect = 0.63
Identities = 18/46 (39%), Positives = 23/46 (50%)
Query: 141 ESVLQLGRALTAHLYSLLQTQHALGDAFADLSQKSPELQEEFGYNA 186
E+VLQLG +T + +LQ H + F Q ELQ E G A
Sbjct: 28 ETVLQLGAWMTVRGWVVLQKGHGMKQLFGSELQAESELQAELGTGA 73
>gi|239751432 PREDICTED: hypothetical protein XP_002347870 [Homo
sapiens]
Length = 161
Score = 32.3 bits (72), Expect = 0.63
Identities = 18/46 (39%), Positives = 23/46 (50%)
Query: 141 ESVLQLGRALTAHLYSLLQTQHALGDAFADLSQKSPELQEEFGYNA 186
E+VLQLG +T + +LQ H + F Q ELQ E G A
Sbjct: 28 ETVLQLGAWMTVRGWVVLQKGHGMKQLFGSELQAESELQAELGTGA 73
>gi|239745936 PREDICTED: hypothetical protein XP_002343581 [Homo
sapiens]
Length = 161
Score = 32.3 bits (72), Expect = 0.63
Identities = 18/46 (39%), Positives = 23/46 (50%)
Query: 141 ESVLQLGRALTAHLYSLLQTQHALGDAFADLSQKSPELQEEFGYNA 186
E+VLQLG +T + +LQ H + F Q ELQ E G A
Sbjct: 28 ETVLQLGAWMTVRGWVVLQKGHGMKQLFGSELQAESELQAELGTGA 73
>gi|118130809 endothelial cell-specific chemotaxis regulator [Homo
sapiens]
Length = 205
Score = 31.6 bits (70), Expect = 1.1
Identities = 17/50 (34%), Positives = 22/50 (44%), Gaps = 9/50 (18%)
Query: 41 SGPNLNETSIVSGGYGG---------SGDGLIPTGSGRHPSHSTTPSGPG 81
S P + +TS GG GG S G IP+ PSH ++ PG
Sbjct: 24 SQPTMTQTSSSQGGLGGLSLTTEPVSSNPGYIPSSEANRPSHLSSTGTPG 73
>gi|31559829 keratin 25 [Homo sapiens]
Length = 450
Score = 31.2 bits (69), Expect = 1.4
Identities = 40/154 (25%), Positives = 61/154 (39%), Gaps = 22/154 (14%)
Query: 150 LTAHLYSLLQTQHALGDAFADLSQKSPELQEEFGYNAETQKLLCKNGETLLGAVNFFVSS 209
L L S L + HAL +A ADL QK E+FG + C+ + +
Sbjct: 86 LNDRLASYLDSVHALEEANADLEQKIKGWYEKFGPGS------CRGLDHDYSRYFPIIDD 139
Query: 210 INTLVTKTMEDTLMTVKQYEAARLEYDAYRTDLE-ELSLGPRDAGTRGRLESAQATFQAH 268
+ + + V Q + ARL D +R E EL+L +S +A
Sbjct: 140 LKNQIIASTTSNANAVLQIDNARLTADDFRLKYENELALH----------QSVEADVNGL 189
Query: 269 R---DKYEKLRGDVAIKLKFLEENK--IKVMHKQ 297
R D+ R D+ I+ + L E +K HK+
Sbjct: 190 RRVLDEITLCRTDLEIQYETLSEEMTYLKKNHKE 223
>gi|5032173 nuclear receptor subfamily 2, group F, member 1 [Homo
sapiens]
Length = 423
Score = 31.2 bits (69), Expect = 1.4
Identities = 20/51 (39%), Positives = 23/51 (45%), Gaps = 2/51 (3%)
Query: 42 GPNLNETSIVSGGYGGSGDGLIPTGSGRHPSHSTTPSGPGDEVARGIAGEK 92
GPN GG GG+G+ GSG P TP PG G AG+K
Sbjct: 22 GPN-PAAQAARGGGGGAGEQQQQAGSGA-PHTPQTPGQPGAPATPGTAGDK 70
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.314 0.133 0.374
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 13,240,456
Number of Sequences: 37866
Number of extensions: 621619
Number of successful extensions: 1943
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 22
Number of HSP's successfully gapped in prelim test: 43
Number of HSP's that attempted gapping in prelim test: 1902
Number of HSP's gapped (non-prelim): 88
length of query: 341
length of database: 18,247,518
effective HSP length: 103
effective length of query: 238
effective length of database: 14,347,320
effective search space: 3414662160
effective search space used: 3414662160
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.